WorldWideScience

Sample records for previous modelling results

  1. Columnar modelling of nucleation burst evolution in the convective boundary layer – first results from a feasibility study Part IV: A compilation of previous observations for valuation of simulation results from a columnar modelling study

    Directory of Open Access Journals (Sweden)

    O. Hellmuth

    2006-01-01

    Full Text Available In the preceding Papers I, II and III a revised columnar high-order modelling approach to model gas-aerosol-turbulence interactions in the convective boundary layer (CBL was proposed, and simulation results of two synthetic nucleation scenarios (binary vs. ternary on new particle formation (NPF in the anthropogenically influenced CBL were presented and discussed. The purpose of the present finishing Paper IV is twofold: Firstly, an attempt is made to compile previous observational findings on NPF bursts in the CBL, obtained from a number of field experiments. Secondly, the scenario simulations discussed in Paper III will be evaluated with respect to the role of CBL turbulence in NPF burst evolution. It was demonstrated, that completely different nucleation mechanisms can lead to the occurrence of NPF bursts in the surface layer, but the corresponding evolution patterns strongly differ with respect to the origin, amplitude and phase of the NPF burst as well as with respect to the time-height evolution of turbulent vertical fluxes and double correlation terms of physicochemical and aerosoldynamical variables. The large differences between the binary and ternary case scenario indicate, that ammonia (NH3 can not be considered as a time-independent tuning parameter in nucleation modelling. Its contribution to the evolution of the NPF burst pattern is much more complicated and reflects the influence of CBL turbulence as well as the strong non-linearity of the ternary nucleation rate. The impact of water (H2O vapour on the nucleation rate is quite varying depending on the considered nucleation mechanism. According to the classical theory of binary nucleation involving H2O and sulphuric acid (H2SO4, H2O vapour favours NPF, according to the classical theory of ternary nuncleation involving H2O, H2SO4 and NH3 and according to organic nucleation via chemical reactions involving stabilised Criegee intermediates (SCIs, H2O vapour disfavours nucleation, and

  2. Previous Experience a Model of Practice UNAE

    OpenAIRE

    Ormary Barberi Ruiz; María Dolores Pesántez Palacios

    2017-01-01

    The statements presented in this article represents a preliminary version of the proposed model of pre-professional practices (PPP) of the National University of Education (UNAE) of Ecuador, an urgent institutional necessity is revealed in the descriptive analyzes conducted from technical support - administrative (reports, interviews, testimonials), pedagogical foundations of UNAE (curricular directionality, transverse axes in practice, career plan, approach and diagnostic examination as subj...

  3. Previous Experience a Model of Practice UNAE

    Directory of Open Access Journals (Sweden)

    Ormary Barberi Ruiz

    2017-02-01

    Full Text Available The statements presented in this article represents a preliminary version of the proposed model of pre-professional practices (PPP of the National University of Education (UNAE of Ecuador, an urgent institutional necessity is revealed in the descriptive analyzes conducted from technical support - administrative (reports, interviews, testimonials, pedagogical foundations of UNAE (curricular directionality, transverse axes in practice, career plan, approach and diagnostic examination as subject nature of the pre professional practice and the demand of socio educational contexts where the practices have been emerging to resize them. By relating these elements allowed conceiving the modeling of the processes of the pre-professional practices for the development of professional skills of future teachers through four components: contextual projective, implementation (tutoring, accompaniment (teaching couple and monitoring (meetings at the beginning, during and end of practice. The initial training of teachers is inherent to teaching (academic and professional training, research and links with the community, these are fundamental pillars of Ecuadorian higher education.

  4. MCNP HPGe detector benchmark with previously validated Cyltran model.

    Science.gov (United States)

    Hau, I D; Russ, W R; Bronson, F

    2009-05-01

    An exact copy of the detector model generated for Cyltran was reproduced as an MCNP input file and the detection efficiency was calculated similarly with the methodology used in previous experimental measurements and simulation of a 280 cm(3) HPGe detector. Below 1000 keV the MCNP data correlated to the Cyltran results within 0.5% while above this energy the difference between MCNP and Cyltran increased to about 6% at 4800 keV, depending on the electron cut-off energy.

  5. A website evaluation model by integration of previous evaluation models using a quantitative approach

    Directory of Open Access Journals (Sweden)

    Ali Moeini

    2015-01-01

    Full Text Available Regarding the ecommerce growth, websites play an essential role in business success. Therefore, many authors have offered website evaluation models since 1995. Although, the multiplicity and diversity of evaluation models make it difficult to integrate them into a single comprehensive model. In this paper a quantitative method has been used to integrate previous models into a comprehensive model that is compatible with them. In this approach the researcher judgment has no role in integration of models and the new model takes its validity from 93 previous models and systematic quantitative approach.

  6. Determination of the Boltzmann constant with cylindrical acoustic gas thermometry: new and previous results combined

    Science.gov (United States)

    Feng, X. J.; Zhang, J. T.; Lin, H.; Gillis, K. A.; Mehl, J. B.; Moldover, M. R.; Zhang, K.; Duan, Y. N.

    2017-10-01

    We report a new determination of the Boltzmann constant k B using a cylindrical acoustic gas thermometer. We determined the length of the copper cavity from measurements of its microwave resonance frequencies. This contrasts with our previous work (Zhang et al 2011 Int. J. Thermophys. 32 1297, Lin et al 2013 Metrologia 50 417, Feng et al 2015 Metrologia 52 S343) that determined the length of a different cavity using two-color optical interferometry. In this new study, the half-widths of the acoustic resonances are closer to their theoretical values than in our previous work. Despite significant changes in resonator design and the way in which the cylinder length is determined, the value of k B is substantially unchanged. We combined this result with our four previous results to calculate a global weighted mean of our k B determinations. The calculation follows CODATA’s method (Mohr and Taylor 2000 Rev. Mod. Phys. 72 351) for obtaining the weighted mean value of k B that accounts for the correlations among the measured quantities in this work and in our four previous determinations of k B. The weighted mean {{\\boldsymbol{\\hat{k}}}{B}} is 1.380 6484(28)  ×  10-23 J K-1 with the relative standard uncertainty of 2.0  ×  10-6. The corresponding value of the universal gas constant is 8.314 459(17) J K-1 mol-1 with the relative standard uncertainty of 2.0  ×  10-6.

  7. Validation of SWAT+ at field level and comparison with previous SWAT models in simulating hydrologic quantity

    Science.gov (United States)

    GAO, J.; White, M. J.; Bieger, K.; Yen, H.; Arnold, J. G.

    2017-12-01

    Over the past 20 years, the Soil and Water Assessment Tool (SWAT) has been adopted by many researches to assess water quantity and quality in watersheds around the world. As the demand increases in facilitating model support, maintenance, and future development, the SWAT source code and data have undergone major modifications over the past few years. To make the model more flexible in terms of interactions of spatial units and processes occurring in watersheds, a completely revised version of SWAT (SWAT+) was developed to improve SWAT's ability in water resource modelling and management. There are only several applications of SWAT+ in large watersheds, however, no study pays attention to validate the new model at field level and assess its performance. To test the basic hydrologic function of SWAT+, it was implemented in five field cases across five states in the U.S. and compared the SWAT+ created results with that from the previous models at the same fields. Additionally, an automatic calibration tool was used to test which model is easier to be calibrated well in a limited number of parameter adjustments. The goal of the study was to evaluate the performance of SWAT+ in simulating stream flow on field level at different geographical locations. The results demonstrate that SWAT+ demonstrated similar performance with previous SWAT model, but the flexibility offered by SWAT+ via the connection of different spatial objects can result in a more accurate simulation of hydrological processes in spatial, especially for watershed with artificial facilities. Autocalibration shows that SWAT+ is much easier to obtain a satisfied result compared with the previous SWAT. Although many capabilities have already been enhanced in SWAT+, there exist inaccuracies in simulation. This insufficiency will be improved with advancements in scientific knowledge on hydrologic process in specific watersheds. Currently, SWAT+ is prerelease, and any errors are being addressed.

  8. Initial results of CyberKnife treatment for recurrent previously irradiated head and neck cancer

    International Nuclear Information System (INIS)

    Himei, Kengo; Katsui, Kuniaki; Yoshida, Atsushi

    2003-01-01

    The purpose of this study was to evaluate the efficacy of CyberKnife for recurrent previously irradiated head and neck cancer. Thirty-one patients with recurrent previously irradiated head and neck cancer were treated with a CyberKnife from July 1999 to March 2002 at Okayama Kyokuto Hospital were retrospectively studied. The accumulated dose was 28-80 Gy (median 60 Gy). The interval between CyberKnife treatment and previous radiotherapy was 0.4-429.5 months (median 16.3 months). Primary lesions were nasopharynx: 7, maxillary sinus: 6, tongue: 5, ethmoid sinus: 3, and others: 1. The pathology was squamous cell carcinoma: 25, adenoid cystic carcinoma: 4, and others: 2. Symptoms were pain: 8, and nasal bleeding: 2. The prescribed dose was 15.0-40.3 Gy (median 32.3 Gy) as for the marginal dose. The response rate (complete response (CR)+partial response (PR)) and local control rate (CR+PR+no change (NC)) was 74% and 94% respectively. Pain disappeared for 4 cases, relief was obtained for 4 cases and no change for 2 cases and nasal bleeding disappeared for 2 cases for an improvement of symptoms. An adverse effects were observed as mucositis in 5 cases and neck swelling in one case. Prognosis of recurrent previously irradiated head and neck cancer was estimated as poor. Our early experience shows that CyberKnife is expected to be feasible treatment for recurrent previously irradiated head and neck cancer, and for the reduction adverse effects and maintenance of useful quality of life (QOL) for patients. (author)

  9. Atmospheric Deposition Modeling Results

    Data.gov (United States)

    U.S. Environmental Protection Agency — This asset provides data on model results for dry and total deposition of sulfur, nitrogen and base cation species. Components include deposition velocities, dry...

  10. Does a previous prostate biopsy-related acute bacterial prostatitis affect the results of radical prostatectomy?

    Directory of Open Access Journals (Sweden)

    Hakan Türk

    Full Text Available ABSTRACT Objective To The standard technique for obtaining a histologic diagnosis of prostatic carcinomas is transrectal ultrasound guided prostate biopsy. Acute prostatitis which might develop after prostate biopsy can cause periprostatic inflammation and fibrosis. In this study, we performed a retrospective review of our database to determine whether ABP history might affect the outcome of RP. Materials and Methods 441 RP patients who were operated in our clinic from 2002 to 2014 were included in our study group. All patients’ demographic values, PSA levels, biopsy and radical prostatectomy specimen pathology results and their perioperative/ postoperative complications were evaluated. Results There were 41 patients in patients with acute prostatitis following biopsy and 397 patients that did not develop acute prostatitis. Mean blood loss, transfusion rate and operation period were found to be significantly higher in ABP patients. Hospitalization period and reoperation rates were similar in both groups. However, post-op complications were significantly higher in ABP group. Conclusion Even though it does not affect oncological outcomes, we would like to warn the surgeons for potential complaints during surgery in ABP patients.

  11. Does a previous prostate biopsy-related acute bacterial prostatitis affect the results of radical prostatectomy?

    Science.gov (United States)

    Türk, Hakan; Ün, Sitki; Arslan, Erkan; Zorlu, Ferruh

    2018-01-01

    To The standard technique for obtaining a histologic diagnosis of prostatic carcinomas is transrectal ultrasound guided prostate biopsy. Acute prostatitis which might develop after prostate biopsy can cause periprostatic inflammation and fibrosis. In this study, we performed a retrospective review of our database to determine whether ABP history might affect the outcome of RP. 441 RP patients who were operated in our clinic from 2002 to 2014 were included in our study group. All patients' demographic values, PSA levels, biopsy and radical prostatectomy specimen pathology results and their perioperative/postoperative complications were evaluated. There were 41 patients in patients with acute prostatitis following biopsy and 397 patients that did not develop acute prostatitis. Mean blood loss, transfusion rate and operation period were found to be significantly higher in ABP patients. Hospitalization period and reoperation rates were similar in both groups. However, post-op complications were significantly higher in ABP group. Even though it does not affect oncological outcomes, we would like to warn the surgeons for potential complaints during surgery in ABP patients. Copyright® by the International Brazilian Journal of Urology.

  12. A methodology for modeling photocatalytic reactors for indoor pollution control using previously estimated kinetic parameters

    Energy Technology Data Exchange (ETDEWEB)

    Passalia, Claudio; Alfano, Orlando M. [INTEC - Instituto de Desarrollo Tecnologico para la Industria Quimica, CONICET - UNL, Gueemes 3450, 3000 Santa Fe (Argentina); FICH - Departamento de Medio Ambiente, Facultad de Ingenieria y Ciencias Hidricas, Universidad Nacional del Litoral, Ciudad Universitaria, 3000 Santa Fe (Argentina); Brandi, Rodolfo J., E-mail: rbrandi@santafe-conicet.gov.ar [INTEC - Instituto de Desarrollo Tecnologico para la Industria Quimica, CONICET - UNL, Gueemes 3450, 3000 Santa Fe (Argentina); FICH - Departamento de Medio Ambiente, Facultad de Ingenieria y Ciencias Hidricas, Universidad Nacional del Litoral, Ciudad Universitaria, 3000 Santa Fe (Argentina)

    2012-04-15

    Highlights: Black-Right-Pointing-Pointer Indoor pollution control via photocatalytic reactors. Black-Right-Pointing-Pointer Scaling-up methodology based on previously determined mechanistic kinetics. Black-Right-Pointing-Pointer Radiation interchange model between catalytic walls using configuration factors. Black-Right-Pointing-Pointer Modeling and experimental validation of a complex geometry photocatalytic reactor. - Abstract: A methodology for modeling photocatalytic reactors for their application in indoor air pollution control is carried out. The methodology implies, firstly, the determination of intrinsic reaction kinetics for the removal of formaldehyde. This is achieved by means of a simple geometry, continuous reactor operating under kinetic control regime and steady state. The kinetic parameters were estimated from experimental data by means of a nonlinear optimization algorithm. The second step was the application of the obtained kinetic parameters to a very different photoreactor configuration. In this case, the reactor is a corrugated wall type using nanosize TiO{sub 2} as catalyst irradiated by UV lamps that provided a spatially uniform radiation field. The radiative transfer within the reactor was modeled through a superficial emission model for the lamps, the ray tracing method and the computation of view factors. The velocity and concentration fields were evaluated by means of a commercial CFD tool (Fluent 12) where the radiation model was introduced externally. The results of the model were compared experimentally in a corrugated wall, bench scale reactor constructed in the laboratory. The overall pollutant conversion showed good agreement between model predictions and experiments, with a root mean square error less than 4%.

  13. Surgical Results of Trabeculectomy and Ahmed Valve Implantation Following a Previous Failed Trabeculectomy in Primary Congenital Glaucoma Patients

    OpenAIRE

    Lee, Naeun; Ma, Kyoung Tak; Bae, Hyoung Won; Hong, Samin; Seong, Gong Je; Hong, Young Jae; Kim, Chan Yun

    2015-01-01

    Purpose To compare the surgical results of trabeculectomy and Ahmed glaucoma valve implantation after a previous failed trabeculectomy. Methods A retrospective comparative case series review was performed on 31 eye surgeries in 20 patients with primary congenital glaucoma who underwent trabeculectomy or Ahmed glaucoma valve implantation after a previous failed trabeculectomy with mitomycin C. Results The preoperative mean intraocular pressure was 25.5 mmHg in the trabeculectomy group and 26.9...

  14. The Importance of Business Model Factors for Cloud Computing Adoption: Role of Previous Experiences

    Directory of Open Access Journals (Sweden)

    Bogataj Habjan Kristina

    2017-08-01

    Full Text Available Background and Purpose: Bringing several opportunities for more effective and efficient IT governance and service exploitation, cloud computing is expected to impact the European and global economies significantly. Market data show that despite many advantages and promised benefits the adoption of cloud computing is not as fast and widespread as foreseen. This situation shows the need for further exploration of the potentials of cloud computing and its implementation on the market. The purpose of this research was to identify individual business model factors with the highest impact on cloud computing adoption. In addition, the aim was to identify the differences in opinion regarding the importance of business model factors on cloud computing adoption according to companies’ previous experiences with cloud computing services.

  15. Surgical results of trabeculectomy and Ahmed valve implantation following a previous failed trabeculectomy in primary congenital glaucoma patients.

    Science.gov (United States)

    Lee, Naeun; Ma, Kyoung Tak; Bae, Hyoung Won; Hong, Samin; Seong, Gong Je; Hong, Young Jae; Kim, Chan Yun

    2015-04-01

    To compare the surgical results of trabeculectomy and Ahmed glaucoma valve implantation after a previous failed trabeculectomy. A retrospective comparative case series review was performed on 31 eye surgeries in 20 patients with primary congenital glaucoma who underwent trabeculectomy or Ahmed glaucoma valve implantation after a previous failed trabeculectomy with mitomycin C. The preoperative mean intraocular pressure was 25.5 mmHg in the trabeculectomy group and 26.9 mmHg in the Ahmed glaucoma valve implantation group (p = 0.73). The 48-month postoperative mean intraocular pressure was 19.6 mmHg in the trabeculectomy group and 20.2 mmHg in the Ahmed glaucoma valve implantation group (p = 0.95). The 12-month trabeculectomy success rate was 69%, compared with 64% for Ahmed glaucoma valve implantation, and the 48-month success rates were 42% and 36% for trabeculectomy and valve implantation, respectively. The success rates following the entire follow-up period were not significantly different between the two groups (p > 0.05 by log rank test). Postoperative complications occurred in 25% of the trabeculectomy-operated eyes and 9% of the Ahmed-implanted eyes (p = 0.38). There was no significant difference in surgical outcome between the trabeculectomy and Ahmed glaucoma valve implantation groups, neither of which had favorable results. However, the trabeculectomy group demonstrated a higher prevalence of adverse complications such as post-operative endophthalmitis.

  16. Everolimus for Previously Treated Advanced Gastric Cancer: Results of the Randomized, Double-Blind, Phase III GRANITE-1 Study

    Science.gov (United States)

    Ohtsu, Atsushi; Ajani, Jaffer A.; Bai, Yu-Xian; Bang, Yung-Jue; Chung, Hyun-Cheol; Pan, Hong-Ming; Sahmoud, Tarek; Shen, Lin; Yeh, Kun-Huei; Chin, Keisho; Muro, Kei; Kim, Yeul Hong; Ferry, David; Tebbutt, Niall C.; Al-Batran, Salah-Eddin; Smith, Heind; Costantini, Chiara; Rizvi, Syed; Lebwohl, David; Van Cutsem, Eric

    2013-01-01

    Purpose The oral mammalian target of rapamycin inhibitor everolimus demonstrated promising efficacy in a phase II study of pretreated advanced gastric cancer. This international, double-blind, phase III study compared everolimus efficacy and safety with that of best supportive care (BSC) in previously treated advanced gastric cancer. Patients and Methods Patients with advanced gastric cancer that progressed after one or two lines of systemic chemotherapy were randomly assigned to everolimus 10 mg/d (assignment schedule: 2:1) or matching placebo, both given with BSC. Randomization was stratified by previous chemotherapy lines (one v two) and region (Asia v rest of the world [ROW]). Treatment continued until disease progression or intolerable toxicity. Primary end point was overall survival (OS). Secondary end points included progression-free survival (PFS), overall response rate, and safety. Results Six hundred fifty-six patients (median age, 62.0 years; 73.6% male) were enrolled. Median OS was 5.4 months with everolimus and 4.3 months with placebo (hazard ratio, 0.90; 95% CI, 0.75 to 1.08; P = .124). Median PFS was 1.7 months and 1.4 months in the everolimus and placebo arms, respectively (hazard ratio, 0.66; 95% CI, 0.56 to 0.78). Common grade 3/4 adverse events included anemia, decreased appetite, and fatigue. The safety profile was similar in patients enrolled in Asia versus ROW. Conclusion Compared with BSC, everolimus did not significantly improve overall survival for advanced gastric cancer that progressed after one or two lines of previous systemic chemotherapy. The safety profile observed for everolimus was consistent with that observed for everolimus in other cancers. PMID:24043745

  17. Passive acoustic monitoring using a towed hydrophone array results in identification of a previously unknown beaked whale habitat.

    Science.gov (United States)

    Yack, Tina M; Barlow, Jay; Calambokidis, John; Southall, Brandon; Coates, Shannon

    2013-09-01

    Beaked whales are diverse and species rich taxa. They spend the vast majority of their time submerged, regularly diving to depths of hundreds to thousands of meters, typically occur in small groups, and behave inconspicuously at the surface. These factors make them extremely difficult to detect using standard visual survey methods. However, recent advancements in acoustic detection capabilities have made passive acoustic monitoring (PAM) a viable alternative. Beaked whales can be discriminated from other odontocetes by the unique characteristics of their echolocation clicks. In 2009 and 2010, PAM methods using towed hydrophone arrays were tested. These methods proved highly effective for real-time detection of beaked whales in the Southern California Bight (SCB) and were subsequently implemented in 2011 to successfully detect and track beaked whales during the ongoing Southern California Behavioral Response Study. The three year field effort has resulted in (1) the successful classification and tracking of Cuvier's (Ziphius cavirostris), Baird's (Berardius bairdii), and unidentified Mesoplodon beaked whale species and (2) the identification of areas of previously unknown beaked whale habitat use. Identification of habitat use areas will contribute to a better understanding of the complex relationship between beaked whale distribution, occurrence, and preferred habitat characteristics on a relatively small spatial scale. These findings will also provide information that can be used to promote more effective management and conservation of beaked whales in the SCB, a heavily used Naval operation and training region.

  18. COMPARISON OF THE RESULTS OF BLOOD GLUCOSE SELFMONITORING AND CONTINUOUS GLUCOSE MONITORING IN PREGNANT WOMEN WITH PREVIOUS DIABETES MELLITUS

    Directory of Open Access Journals (Sweden)

    A. V. Dreval'

    2015-01-01

    Full Text Available Background: Pregnancy is one of the indications for continuous glucose monitoring (CGM. The data on its efficiency in pregnant women are contradictory.Aim: To compare the results of blood glucose self-monitoring (SMBG and CGM in pregnant women with previous diabetes mellitus.Materials and methods: We performed a cross-sectional comparative study of glycemia in 18 pregnant women with previous type 1 (87.8% of patients and type 2 diabetes (22.2% of patients with various degrees of glycemic control. Their age was 27.7 ± 4.9 year. At study entry, the patients were at 17.2 ± 6.1 weeks of gestation. CGM and SMBG were performed in and by all patients for the duration of 5.4 ± 1.5 days. Depending on their HbA1c levels, all patients were divided into two groups: group 1 – 12 women with the HbA1c above the target (8.5 ± 1%, and group 2 – 6 women with the HbA1c levels within the target (5.6 ± 0.3%.Results: According to SMBG results, women from group 2 had above-the-target glycemia levels before breakfast, at 1 hour after breakfast and at bedtime: 6.2 ± 1.6, 8.7 ± 2.1, and 5.7 ± 1.9 mmol/L, respectively. According to CGM, patients from group 1 had higher postprandial glycemia than those from group 2 (8.0 ± 2.1 and 6.9 ± 1.8 mmol/L, respectively, p = 0.03. The analysis of glycemia during the day time revealed significant difference between the groups only at 1 hour after dinner (7.1 ± 1.4 mmol/L in group 1 and 5.8 ± 0.9 mmol/L in group 2, р = 0.041 and the difference was close to significant before lunch (6.0 ± 2.2 mmol/L in group 1 and 4.8 ± 1.0 mmol/L in group 2, р = 0.053. Comparison of SMBG and CGM results demonstrated significant difference only at one timepoint (at 1 hour after lunch and only in group 1: median glycemia was 7.4 [6.9; 8.1] mmol/L by SMBG and 6 [5.4; 6.6] mmol/L by CGM measurement (р = 0.001. Lower median values by CGM measurement could be explained by averaging of three successive measurements carried out in the

  19. Third metacarpal condylar fatigue fractures in equine athletes occur within previously modelled subchondral bone.

    Science.gov (United States)

    Whitton, R Christopher; Trope, Gareth D; Ghasem-Zadeh, Ali; Anderson, Garry A; Parkin, Timothy D H; Mackie, Eleanor J; Seeman, Ego

    2010-10-01

    Bone modelling and remodelling reduce the risk of fatigue fractures; the former by adapting bone to its loading circumstances, the latter by replacing fatigued bone. Remodelling transiently increases porosity because of the normal delay in onset of the formation phase of the remodelling sequence. Protracted intense loading suppresses remodelling leaving modelling as the only means of maintaining bone strength. We therefore hypothesized that race horses with fatigue fractures of the distal third metacarpal bone (MC3) will have reduced porosity associated with suppressed remodelling while continued adaptive modelling will result in higher volume fraction (BV/TV) at this site. Using high resolution peripheral quantitative computed tomography (HR-pQCT), we measured the distal aspect of the MC3 obtained at postmortem from 13 thoroughbred race horses with condylar fractures of the MC3 (cases), 8 horses without fractures (training controls), 14 horses with a fracture at another site (fractured controls) and 9 horses resting from training (resting controls). Porosity of the subchondral bone of MC3 was lower in cases than resting controls (12±1.4% vs. 18±1.6%, P=0.017) although areas of focal porosity were observed adjacent to fractures in 6/13 horses. BV/TV of the distal metacarpal epiphysis tended to be higher in horses with condylar fractures (0.79±0.015) than training controls (0.74±0.019, P=0.070), but also higher in controls with a fracture elsewhere (0.79±0.014) than the training controls (0.74±0.019, P=0.040). BV/TV was higher in horses over three years of age than those aged two or three years (0.79±0.01 vs. 0.74±0.01, P=0.016). All metacarpal condylar fractures occurred within focal areas of high BV/TV. We infer that intense training in equine athletes suppresses remodelling of third metacarpal subchondral bone limiting damage repair while modelling increases regional bone volume in an attempt to minimise local stresses but may fail to offset bone

  20. New Ages for Gorgona Island, Colombia: Implications for Previous Petrogenetic and Tectonic Models

    Science.gov (United States)

    Serrano Duran, L.; Lopez Martinez, M.; Ferrari, L.

    2007-05-01

    reliable plateau and/or isochron ages. Only one basaltic sample, located in the western coast, yielded an age comparable with those previously reported in the literature. For two basalts intercalated with komatiites and a gabbro exposed in the north-eastern coast of the island we obtained younger ages, similar to those reported for some mafic and ultramafic rocks along the Pacific coast of Colombia. The two sets of ages for the ultramafic suite of Gorgona also correspond to different petrologic types. The depleted rocks in the eastern coast are younger than the enriched basalts and picrites located in the southern and western part of the island with ages around 90 Ma, suggesting a more complex tectonic evolution with the accretion of at least two different blocks. This eventually questions the "single plume" model for the formation of the Gorgona Island plateau.

  1. Overview of JET post-mortem results following the 2007-9 operational period, and comparisons with previous campaigns

    International Nuclear Information System (INIS)

    Coad, J P; Gruenhagen, S; Widdowson, A; Hole, D E; Hakola, A; Koivuranta, S; Likonen, J; Rubel, M

    2011-01-01

    In 2010, all the plasma-facing components were removed from JET so that the carbon-based surfaces could be replaced with beryllium (Be) or tungsten as part of the ITER-like wall (ILW) project. This gives unprecedented opportunities for post-mortem analyses of these plasma-facing surfaces; this paper reviews the data obtained so far and relates the information to studies of tiles removed during previous JET shutdowns. The general pattern of erosion/deposition at the JET divertor has been maintained, with deposition of impurities in the scrape-off layer (SOL) at the inner divertor and preferential removal of carbon and transport into the corner. However, the remaining films in the SOL contain very high Be/C ratios at the surface. The first measurements of erosion using a tile profiler have been completed, with up to 200 microns erosion being recorded at points on the inner wall guard limiters.

  2. Mechanical and histological characterization of the abdominal muscle. A previous step to modelling hernia surgery.

    Science.gov (United States)

    Hernández, B; Peña, E; Pascual, G; Rodríguez, M; Calvo, B; Doblaré, M; Bellón, J M

    2011-04-01

    The aims of this study are to experimentally characterize the passive elastic behaviour of the rabbit abdominal wall and to develop a mechanical constitutive law which accurately reproduces the obtained experimental results. For this purpose, tissue samples from New Zealand White rabbits 2150±50 (g) were mechanically tested in vitro. Mechanical tests, consisting of uniaxial loading on tissue samples oriented along the craneo-caudal and the perpendicular directions, respectively, revealed the anisotropic non-linear mechanical behaviour of the abdominal tissues. Experiments were performed considering the composite muscle (including external oblique-EO, internal oblique-IO and transverse abdominis-TA muscle layers), as well as separated muscle layers (i.e., external oblique, and the bilayer formed by internal oblique and transverse abdominis). Both the EO muscle layer and the IO-TA bilayer demonstrated a stiffer behaviour along the transversal direction to muscle fibres than along the longitudinal one. The fibre arrangement was measured by means of a histological study which confirmed that collagen fibres are mainly responsible for the passive mechanical strength and stiffness. Furthermore, the degree of anisotropy of the abdominal composite muscle turned out to be less pronounced than those obtained while studying the EO and IO-TA separately. Moreover, a phenomenological constitutive law was used to capture the measured experimental curves. A Levenberg-Marquardt optimization algorithm was used to fit the model constants to reproduce the experimental curves. Copyright © 2010 Elsevier Ltd. All rights reserved.

  3. Ifosfamide in previously untreated disseminated neuroblastoma. Results of Study 3A of the European Neuroblastoma Study Group.

    Science.gov (United States)

    Kellie, S J; De Kraker, J; Lilleyman, J S; Bowman, A; Pritchard, J

    1988-05-01

    A prospective study of the effectiveness of ifosfamide as a single agent in the management of previously untreated patients with Evans stage IV neuroblastoma was undertaken. Eighteen children aged more than 1 year were treated with ifosfamide (IFX) 3 g/m2 daily for 2 days immediately after diagnosis and 3 weeks later. Treatment was continued with combination chemotherapy using vincristine, cyclophosphamide, cisplatinum and etoposide (OPEC) or a variant. Mesna (2-mercaptoethane sulphonate) was given to all patients during IFX treatment to prevent urotoxicity. Eight of the 18 patients (44%) responded to IFX. Nine had greater than 66% reduction in baseline tumor volume. Of 15 evaluable patients with raised pre-treatment urinary catecholamine excretion, six (40%) achieved greater than 50% reduction in pretreatment levels. Two of 10 patients evaluable for bone marrow response had complete clearance. Toxicity was mild in all patients. Upon completing 'first line' therapy, only four patients (22%) achieved a good partial remission (GPR) or complete response (CR). Median survival was 11 months. There was a lower rate of attaining GPR and shortened median survival in patients receiving phase II IFX before OPEC or variant, compared to patients with similar pre-treatment characteristics treated with OPEC from diagnosis in an earlier study.

  4. Long-term follow-up results of 131I treatment of recurrent hyperthyroidism previously treated by subtotal thyroidectomy

    International Nuclear Information System (INIS)

    Bal, C.S.; Padhy, A.K.; Nair, P.G.

    1998-01-01

    Full text: In patients with recurrent hyperthyroidism following previous subtotal thyroidectomy for Graves' disease or toxic MNG, radioiodine therapy is often recommended. However, our knowledge of the long-term effect of 131 I in this subset of patient is limited. 47 patients presented with post surgery recurrence at thyroid clinic of Nuclear Medicine Department from 1972 to 1996. Mean age of patients at presentation was 43 years (range 23-67 years), 10 were males and 28 had Graves' and rest toxic-MNG. Time of recurrence following surgery varied widely from 6 months to 32 years, 21% recurrent within a year and 75% before tenth year. However, 15% recurred beyond 20 years. 11 patients (23.4%) were aged more than 50 years at the time of recurrence. 34 patients (72%) needed single dose of 131 I (mean dose 288 MBq and range 107 - 740 MBq) and remaining 13 patients multiple doses of 131 I, to be free of thyrotoxicosis (7 patients: 2 doses, 3 patients: 3 doses, 2 patients: 4 doses and the last one 5 doses). 38 patients required ≤370 MBq for this purpose. One individual needed the maximum which was 1480 MBq in divided doses to be euthyroid. The maximum duration of follow-up was 26 years with mean follow up of 10 years. 5 patients were lost to follow-up after their 131 I therapy. The end point considered was confirmed hypothyroidism or euthyroidism in the last visit. 26 patients (62%) were euthyroid and 16 (38%) were hypothyroid after 10 years of mean follow-up period. However, hypothyroidism at the end of one year was in eleven patients (26%). Comparing age, sex, type of gland, time of 131 I treatment and RAIU matched non-operated thyrotoxic patients revealed hypothyroidism rate at first year was 9% and cumulative hypothyroidism after 9.8 years of follow-up (ranging 1-26 years) 36%. This study reveals 15% of patients recur even after 20 years, indicating life-long follow-up after thyroidectomy. The 131 I treatment in these patients shows high initial hypothyroidism rate

  5. Continuation of the summarizing interim report on previous results of the Gorleben site survey as of May 1983

    International Nuclear Information System (INIS)

    1990-04-01

    In addition to results from the 1983 interim report, this report contains, in order to supplement the surface explorations, seismic reflection measurements, hydrogeologic and seismologic investigations, sorption experiments, and studies of glacial development in the site region and of long-term safety of final waste repositories in salt domes. The site's high grade of suitability for becoming a final radioactive waste repository, the legal basis as well as quality assurance are evaluated. (orig.) [de

  6. Effects of 60 Hz electromagnetic fields on early growth in three plant species and a replication of previous results

    Energy Technology Data Exchange (ETDEWEB)

    Davis, M.S. [Univ. of Sunderland (United Kingdom). Ecology Centre

    1996-05-01

    In an attempt to replicate the findings of Smith et al., seeds of Raphanus sativus L. (radish), Sinapsis alba L. (mustard), and Hordeum vulgare L. (barley) were grown for between 9 and 21 days in continuous electromagnetic fields (EMFs) at ion-cyclotron resonance conditions for stimulation of Ca{sup 2+} (B{sub H} = 78.3 {micro}T, B{sub HAC} = 40 {micro}T peak-peak at 60 Hz, B{sub v} = 0). On harvesting, radish showed results similar to those of Smith et al. Dry stem weight and plant height were both significantly greater (Mann-Whitney tests, Ps < 0.05) in EMF-exposed plants than in control plants in each EMF experiment. Wet root weight was significantly greater in EMF-exposed plants in two out of three experiments, as were dry leaf weight, dry whole weight, and stem diameter. Dry root weight, wet leaf weight, and wet whole weight were significantly greater in EMF-exposed plants in one of three experiments. All significant differences indicated an increase in weight or size in the EMF-exposed plants. In each of the sham experiments, no differences between exposed and control plants were evident. Mustard plants failed to respond to the EMFs in any of the plant parameters measured. In one experiment, barley similarly failed to respond; but in another showed significantly greater wet root weight and significantly smaller stem diameter and dry seed weight at the end of the experiment in exposed plants compared to control plants. Although these results give no clue about the underlying bioelectromagnetic mechanism, they demonstrate that, at least for one EMF-sensitive biosystem, results can be independently replicated in another laboratory. Such replication is crucial in establishing the validity of bioelectromagnetic science.

  7. Locating previously unknown patterns in data-mining results: a dual data- and knowledge-mining method

    Directory of Open Access Journals (Sweden)

    Knaus William A

    2006-03-01

    Full Text Available Abstract Background Data mining can be utilized to automate analysis of substantial amounts of data produced in many organizations. However, data mining produces large numbers of rules and patterns, many of which are not useful. Existing methods for pruning uninteresting patterns have only begun to automate the knowledge acquisition step (which is required for subjective measures of interestingness, hence leaving a serious bottleneck. In this paper we propose a method for automatically acquiring knowledge to shorten the pattern list by locating the novel and interesting ones. Methods The dual-mining method is based on automatically comparing the strength of patterns mined from a database with the strength of equivalent patterns mined from a relevant knowledgebase. When these two estimates of pattern strength do not match, a high "surprise score" is assigned to the pattern, identifying the pattern as potentially interesting. The surprise score captures the degree of novelty or interestingness of the mined pattern. In addition, we show how to compute p values for each surprise score, thus filtering out noise and attaching statistical significance. Results We have implemented the dual-mining method using scripts written in Perl and R. We applied the method to a large patient database and a biomedical literature citation knowledgebase. The system estimated association scores for 50,000 patterns, composed of disease entities and lab results, by querying the database and the knowledgebase. It then computed the surprise scores by comparing the pairs of association scores. Finally, the system estimated statistical significance of the scores. Conclusion The dual-mining method eliminates more than 90% of patterns with strong associations, thus identifying them as uninteresting. We found that the pruning of patterns using the surprise score matched the biomedical evidence in the 100 cases that were examined by hand. The method automates the acquisition of

  8. A modification of a previous model fo r inflammatory tooth pain: Effects of different capsaicin and formalin concentrations and ibuprofen

    Directory of Open Access Journals (Sweden)

    Maryam Raoof DDS, MS

    2012-09-01

    Full Text Available BACKGROUND AND AIM:This study aimed to solve the problems faced with the previous model of inflammatory tooth painin rats.METHODS:After cutting 2 mm of the distal extremities, the polyethylene crownswere placed on the mandibularincisors. In contrast to the original model, we used flow composite instead of wire in order to maximize the retention ofcrowns. Different concentrations of capsaicin (10, 25 and 100 mg/ml and formalin were administrated into the cavitiesunder the crowns. The algesic agent-induced behaviors were evaluated.RESULTS:The modified model had no liquid leakage. Furthermore, composite allowed the crowns to remain for alonger period of time. Capsaicin 25, 100 mg/ml and formalin applications induced significantly more painfulstimulation compared with control groups (P < 0.001. These responses were significantly reduced by theadministration of ibuprofen, 20 minutes prior to the capsaicin 100 mg/ml injection.CONCLUSIONS:This model seems to be adequate for long-term pain related experiments in which fluid leakageelimination is important.

  9. Making the best use of our previous results as a clue for interpreting kinetics of scintigraphic agents

    Directory of Open Access Journals (Sweden)

    Tsuyoshi Sato

    2011-08-01

    Full Text Available Up to now, we have performed scintigraphy with 201-thallium chloride (201-TlCl and 99m-Tc-hexakis-2-methoxy-isobutyl-isonitrile (99m-Tc-MIBI for malignant tumors and lymphoscintigraphy with 99m-Tc-rhenium-colloid (99m-Tc-Re and 99m-Tc-human-serum-albumin-diethylene-triamine-penta-acetic-acid (99m-Tc-HSA-D for lymph node metastasis. In this article, we re-evaluated scintigraphic images retrospectively with a hope that the results might be a clue, even if it is small, for dentists to try to improve the accuracy of diagnosis of malignant tumors. From scintigraphy, we obtained the tumor retention index as a factor to estimate the uptake of radioactive agents in tumor cells. Moreover, we estimated transport proteins of Na+/K+-ATPase and permeability-glycoprotein (P-gp expressed on the cell membrane that might regulate the kinetic condition of radioactive agents. Among the tumor retention index, the transport protein and the histopathologic finding of tumors, there were relatively well correlations. The tumor retention index showed a difference clearly between malignant tumor and benign tumor. The transport protein revealed a distinct expression in accordance with the malignancy of tumor, and the uptake clearly depended upon the expression of transport protein. Moreover, the lymph node metastasis was detected well by lymphoscintigraphy with 99m-Tc-Re and 99m-Tc-HSA-D.

  10. Bomb-Pulse Chlorine-36 At The Proposed Yucca Mountain Repository Horizon: An Investigation Of Previous Conflicting Results And Collection Of New Data

    International Nuclear Information System (INIS)

    J. Cizdziel

    2006-01-01

    Previous studies by scientists at Los Alamos National Laboratory (LANL) found elevated ratios of chlorine-36 to total chloride ( 36 Cl/Cl) in samples of rock collected from the Exploratory Studies Facility (ESF) and the Enhanced Characterization of the Repository Block (ECRB) at Yucca Mountain as the tunnels were excavated. The data were interpreted as an indication that fluids containing 'bomb-pulse' 36 Cl reached the repository horizon in the ∼50 years since the peak period of above-ground nuclear testing. Moreover, the data support the concept that so-called fast pathways for infiltration not only exist but are active, possibly through a combination of porous media, faults and/or other geologic features. Due to the significance of 36 Cl data to conceptual models of unsaturated zone flow and transport, the United States Geological Survey (USGS) was requested by the Department of Energy (DOE) to design and implement a study to validate the LANL findings. The USGS chose to drill new boreholes at select locations across zones where bomb-pulse ratios had previously been identified. The drill cores were analyzed at Lawrence Livermore National Laboratory (LLNL) for 36 Cl/Cl using both active and passive leaches, with the USGS/LLNL concluding that the active leach extracted too much rock-Cl and the passive leach did not show bomb-pulse ratios. Because consensus was not reached between the USGS/LLNL and LANL on several fundamental points, including the conceptual strategy for sampling, interpretation and use of tritium ( 3 H) data, and the importance and interpretation of blanks, in addition to the presence or absence of bomb-pulse 36 Cl, an evaluation by an independent entity, the University of Nevada, Las Vegas (UNLV), using new samples was initiated. This report is the result of that study. The overall objectives of the UNLV study were to investigate the source or sources of the conflicting results from the previous validation study, and to obtain additional data to

  11. Transcriptomic analysis in a Drosophila model identifies previously implicated and novel pathways in the therapeutic mechanism in neuropsychiatric disorders

    Directory of Open Access Journals (Sweden)

    Priyanka eSingh

    2011-03-01

    Full Text Available We have taken advantage of a newly described Drosophila model to gain insights into the potential mechanism of antiepileptic drugs (AEDs, a group of drugs that are widely used in the treatment of several neurological and psychiatric conditions besides epilepsy. In the recently described Drosophila model that is inspired by pentylenetetrazole (PTZ induced kindling epileptogenesis in rodents, chronic PTZ treatment for seven days causes a decreased climbing speed and an altered CNS transcriptome, with the latter mimicking gene expression alterations reported in epileptogenesis. In the model, an increased climbing speed is further observed seven days after withdrawal from chronic PTZ. We used this post-PTZ withdrawal regime to identify potential AED mechanism. In this regime, treatment with each of the five AEDs tested, namely, ethosuximide (ETH, gabapentin (GBP, vigabatrin (VGB, sodium valproate (NaVP and levetiracetam (LEV, resulted in rescuing of the altered climbing behavior. The AEDs also normalized PTZ withdrawal induced transcriptomic perturbation in fly heads; whereas AED untreated flies showed a large number of up- and down-regulated genes which were enriched in several processes including gene expression and cell communication, the AED treated flies showed differential expression of only a small number of genes that did not enrich gene expression and cell communication processes. Gene expression and cell communication related upregulated genes in AED untreated flies overrepresented several pathways - spliceosome, RNA degradation, and ribosome in the former category, and inositol phosphate metabolism, phosphatidylinositol signaling, endocytosis and hedgehog signaling in the latter. Transcriptome remodeling effect of AEDs was overall confirmed by microarray clustering that clearly separated the profiles of AED treated and untreated flies. Besides being consistent with previously implicated pathways, our results provide evidence for a role of

  12. Improved ability of biological and previous caries multimarkers to predict caries disease as revealed by multivariate PLS modelling

    Directory of Open Access Journals (Sweden)

    Ericson Thorild

    2009-11-01

    Full Text Available Abstract Background Dental caries is a chronic disease with plaque bacteria, diet and saliva modifying disease activity. Here we have used the PLS method to evaluate a multiplicity of such biological variables (n = 88 for ability to predict caries in a cross-sectional (baseline caries and prospective (2-year caries development setting. Methods Multivariate PLS modelling was used to associate the many biological variables with caries recorded in thirty 14-year-old children by measuring the numbers of incipient and manifest caries lesions at all surfaces. Results A wide but shallow gliding scale of one fifth caries promoting or protecting, and four fifths non-influential, variables occurred. The influential markers behaved in the order of plaque bacteria > diet > saliva, with previously known plaque bacteria/diet markers and a set of new protective diet markers. A differential variable patterning appeared for new versus progressing lesions. The influential biological multimarkers (n = 18 predicted baseline caries better (ROC area 0.96 than five markers (0.92 and a single lactobacilli marker (0.7 with sensitivity/specificity of 1.87, 1.78 and 1.13 at 1/3 of the subjects diagnosed sick, respectively. Moreover, biological multimarkers (n = 18 explained 2-year caries increment slightly better than reported before but predicted it poorly (ROC area 0.76. By contrast, multimarkers based on previous caries predicted alone (ROC area 0.88, or together with biological multimarkers (0.94, increment well with a sensitivity/specificity of 1.74 at 1/3 of the subjects diagnosed sick. Conclusion Multimarkers behave better than single-to-five markers but future multimarker strategies will require systematic searches for improved saliva and plaque bacteria markers.

  13. Engineering model cryocooler test results

    International Nuclear Information System (INIS)

    Skimko, M.A.; Stacy, W.D.; McCormick, J.A.

    1992-01-01

    This paper reports that recent testing of diaphragm-defined, Stirling-cycle machines and components has demonstrated cooling performance potential, validated the design code, and confirmed several critical operating characteristics. A breadboard cryocooler was rebuilt and tested from cryogenic to near-ambient cold end temperatures. There was a significant increase in capacity at cryogenic temperatures and the performance results compared will with code predictions at all temperatures. Further testing on a breadboard diaphragm compressor validated the calculated requirement for a minimum axial clearance between diaphragms and mating heads

  14. Modelling the response of stable water isotopes in Greenland precipitation to orbital configurations of the previous interglacial

    Directory of Open Access Journals (Sweden)

    Jesper Sjolte

    2014-09-01

    Full Text Available The relation between δ 18O of precipitation and temperature has been used in numerous studies to reconstruct past temperatures at ice core sites in Greenland and Antarctica. During the past two decades, it has become clear that the slope between δ 18O and temperature varies in both space and time. Here, we use a general circulation model driven by changes in orbital parameters to investigate the Greenland δ 18O–temperature relation for the previous interglacial, the Eemian. In our analysis, we focus on changes in the moisture source regions, and the results underline the importance of taking the seasonality of climate change into account. The orbitally driven experiments show that continental evaporation over North America increases during summer in the warm parts of the Eemian, while marine evaporation decreases. This likely flattens the Greenland δ 18O response to temperature during summer. Since the main climate change in the experiments occurs during summer this adds to a limited response of δ 18O, which is more strongly tied to temperature during winter than during summer. A south–west to north–east gradient in the δ 18O–temperature slope is also evident for Greenland, with low slopes in the south–west and steeper slopes in the north–east. This probably reflects the proportion of continental moisture and Arctic moisture arriving in Greenland, with more continental moisture in the south–west and less in the north–east, and vice versa for the Arctic moisture.

  15. Validation of a Previously Developed Geospatial Model That Predicts the Prevalence of Listeria monocytogenes in New York State Produce Fields.

    Science.gov (United States)

    Weller, Daniel; Shiwakoti, Suvash; Bergholz, Peter; Grohn, Yrjo; Wiedmann, Martin; Strawn, Laura K

    2016-02-01

    Technological advancements, particularly in the field of geographic information systems (GIS), have made it possible to predict the likelihood of foodborne pathogen contamination in produce production environments using geospatial models. Yet, few studies have examined the validity and robustness of such models. This study was performed to test and refine the rules associated with a previously developed geospatial model that predicts the prevalence of Listeria monocytogenes in produce farms in New York State (NYS). Produce fields for each of four enrolled produce farms were categorized into areas of high or low predicted L. monocytogenes prevalence using rules based on a field's available water storage (AWS) and its proximity to water, impervious cover, and pastures. Drag swabs (n = 1,056) were collected from plots assigned to each risk category. Logistic regression, which tested the ability of each rule to accurately predict the prevalence of L. monocytogenes, validated the rules based on water and pasture. Samples collected near water (odds ratio [OR], 3.0) and pasture (OR, 2.9) showed a significantly increased likelihood of L. monocytogenes isolation compared to that for samples collected far from water and pasture. Generalized linear mixed models identified additional land cover factors associated with an increased likelihood of L. monocytogenes isolation, such as proximity to wetlands. These findings validated a subset of previously developed rules that predict L. monocytogenes prevalence in produce production environments. This suggests that GIS and geospatial models can be used to accurately predict L. monocytogenes prevalence on farms and can be used prospectively to minimize the risk of preharvest contamination of produce. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  16. Validation of a Previously Developed Geospatial Model That Predicts the Prevalence of Listeria monocytogenes in New York State Produce Fields

    Science.gov (United States)

    Weller, Daniel; Shiwakoti, Suvash; Bergholz, Peter; Grohn, Yrjo; Wiedmann, Martin

    2015-01-01

    Technological advancements, particularly in the field of geographic information systems (GIS), have made it possible to predict the likelihood of foodborne pathogen contamination in produce production environments using geospatial models. Yet, few studies have examined the validity and robustness of such models. This study was performed to test and refine the rules associated with a previously developed geospatial model that predicts the prevalence of Listeria monocytogenes in produce farms in New York State (NYS). Produce fields for each of four enrolled produce farms were categorized into areas of high or low predicted L. monocytogenes prevalence using rules based on a field's available water storage (AWS) and its proximity to water, impervious cover, and pastures. Drag swabs (n = 1,056) were collected from plots assigned to each risk category. Logistic regression, which tested the ability of each rule to accurately predict the prevalence of L. monocytogenes, validated the rules based on water and pasture. Samples collected near water (odds ratio [OR], 3.0) and pasture (OR, 2.9) showed a significantly increased likelihood of L. monocytogenes isolation compared to that for samples collected far from water and pasture. Generalized linear mixed models identified additional land cover factors associated with an increased likelihood of L. monocytogenes isolation, such as proximity to wetlands. These findings validated a subset of previously developed rules that predict L. monocytogenes prevalence in produce production environments. This suggests that GIS and geospatial models can be used to accurately predict L. monocytogenes prevalence on farms and can be used prospectively to minimize the risk of preharvest contamination of produce. PMID:26590280

  17. Ignition and Growth Modeling of Detonating LX-04 (85% HMX / 15% VITON) Using New and Previously Obtained Experimental Data

    Science.gov (United States)

    Tarver, Craig

    2017-06-01

    An Ignition and Growth reactive flow model for detonating LX-04 (85% HMX / 15% Viton) was developed using new and previously obtained experimental data on: cylinder test expansion; wave curvature; failure diameter; and laser interferometric copper and tantalum foil free surface velocities and LiF interface particle velocity histories. A reaction product JWL EOS generated by the CHEETAH code compared favorably with the existing, well normalized LX-04 product JWL when both were used with the Ignition and Growth model. Good agreement with all existing experimental data was obtained. Keywords: LX-04, HMX, detonation, Ignition and Growth PACS:82.33.Vx, 82.40.Fp This work was performed under the auspices of the U. S. Department of Energy by the Lawrence Livermore National Laboratory under Contract No. DE-AC52-07NA27344.

  18. Results of the naive quark model

    International Nuclear Information System (INIS)

    Gignoux, C.

    1987-10-01

    The hypotheses and limits of the naive quark model are recalled and results on nucleon-nucleon scattering and possible multiquark states are presented. Results show that with this model, ropers do not come. For hadron-hadron interactions, the model predicts Van der Waals forces that the resonance group method does not allow. Known many-body forces are not found in the model. The lack of mesons shows up in the absence of a far reaching force. However, the model does have strengths. It is free from spuriousness of center of mass, and allows a democratic handling of flavor. It has few parameters, and its predictions are very good [fr

  19. Antimicrobial usage in German acute care hospitals: results of the third national point prevalence survey and comparison with previous national point prevalence surveys.

    Science.gov (United States)

    Aghdassi, Seven Johannes Sam; Gastmeier, Petra; Piening, Brar Christian; Behnke, Michael; Peña Diaz, Luis Alberto; Gropmann, Alexander; Rosenbusch, Marie-Luise; Kramer, Tobias Siegfried; Hansen, Sonja

    2018-04-01

    Previous point prevalence surveys (PPSs) revealed the potential for improving antimicrobial usage (AU) in German acute care hospitals. Data from the 2016 German national PPS on healthcare-associated infections and AU were used to evaluate efforts in antimicrobial stewardship (AMS). A national PPS in Germany was organized by the German National Reference Centre for Surveillance of Nosocomial Infections in 2016 as part of the European PPS initiated by the ECDC. The data were collected in May and June 2016. Results were compared with data from the PPS 2011. A total of 218 hospitals with 64 412 observed patients participated in the PPS 2016. The prevalence of patients with AU was 25.9% (95% CI 25.6%-26.3%). No significant increase or decrease in AU prevalence was revealed in the group of all participating hospitals. Prolonged surgical prophylaxis was found to be common (56.1% of all surgical prophylaxes on the prevalence day), but significantly less prevalent than in 2011 (P < 0.01). The most frequently administered antimicrobial groups were penicillins plus β-lactamase inhibitors (BLIs) (23.2%), second-generation cephalosporins (12.9%) and fluoroquinolones (11.3%). Significantly more penicillins plus BLIs and fewer second-generation cephalosporins and fluoroquinolones were used in 2016. Overall, an increase in the consumption of broad-spectrum antimicrobials was noted. For 68.7% of all administered antimicrobials, the indication was documented in the patient notes. The current data reaffirm the points of improvement that previous data identified and reveal that recent efforts in AMS in German hospitals require further intensification.

  20. Previous exercise training has a beneficial effect on renal and cardiovascular function in a model of diabetes.

    Directory of Open Access Journals (Sweden)

    Kleiton Augusto dos Santos Silva

    Full Text Available Exercise training (ET is an important intervention for chronic diseases such as diabetes mellitus (DM. However, it is not known whether previous exercise training intervention alters the physiological and medical complications of these diseases. We investigated the effects of previous ET on the progression of renal disease and cardiovascular autonomic control in rats with streptozotocin (STZ-induced DM. Male Wistar rats were divided into five groups. All groups were followed for 15 weeks. Trained control and trained diabetic rats underwent 10 weeks of exercise training, whereas previously trained diabetic rats underwent 14 weeks of exercise training. Renal function, proteinuria, renal sympathetic nerve activity (RSNA and the echocardiographic parameters autonomic modulation and baroreflex sensitivity (BRS were evaluated. In the previously trained group, the urinary albumin/creatinine ratio was reduced compared with the sedentary diabetic and trained diabetic groups (p<0.05. Additionally, RSNA was normalized in the trained diabetic and previously trained diabetic animals (p<0.05. The ejection fraction was increased in the previously trained diabetic animals compared with the diabetic and trained diabetic groups (p<0.05, and the myocardial performance index was improved in the previously trained diabetic group compared with the diabetic and trained diabetic groups (p<0.05. In addition, the previously trained rats had improved heart rate variability and BRS in the tachycardic response and bradycardic response in relation to the diabetic group (p<0.05. This study demonstrates that previous ET improves the functional damage that affects DM. Additionally, our findings suggest that the development of renal and cardiac dysfunction can be minimized by 4 weeks of ET before the induction of DM by STZ.

  1. Interpreting Results from the Multinomial Logit Model

    DEFF Research Database (Denmark)

    Wulff, Jesper

    2015-01-01

    This article provides guidelines and illustrates practical steps necessary for an analysis of results from the multinomial logit model (MLM). The MLM is a popular model in the strategy literature because it allows researchers to examine strategic choices with multiple outcomes. However, there see...... suitable for both interpretation and communication of results. The pratical steps are illustrated through an application of the MLM to the choice of foreign market entry mode.......This article provides guidelines and illustrates practical steps necessary for an analysis of results from the multinomial logit model (MLM). The MLM is a popular model in the strategy literature because it allows researchers to examine strategic choices with multiple outcomes. However, there seem...... to be systematic issues with regard to how researchers interpret their results when using the MLM. In this study, I present a set of guidelines critical to analyzing and interpreting results from the MLM. The procedure involves intuitive graphical representations of predicted probabilities and marginal effects...

  2. Office and ambulatory blood pressure control with a fixed-dose combination of candesartan and hydrochlorothiazide in previously uncontrolled hypertensive patients: results of CHILI CU Soon

    Science.gov (United States)

    Mengden, Thomas; Hübner, Reinhold; Bramlage, Peter

    2011-01-01

    Background Fixed-dose combinations of candesartan 32 mg and hydrochlorothiazide (HCTZ) have been shown to be effective in clinical trials. Upon market entry we conducted a noninterventional study to document the safety and effectiveness of this fixed-dose combination in an unselected population in primary care and to compare blood pressure (BP) values obtained during office measurement (OBPM) with ambulatory blood pressure measurement (ABPM). Methods CHILI CU Soon was a prospective, noninterventional, noncontrolled, open-label, multicenter study with a follow-up of at least 10 weeks. High-risk patients aged ≥18 years with previously uncontrolled hypertension were started on candesartan 32 mg in a fixed-dose combination with either 12.5 mg or 25 mg HCTZ. OBPM and ABPM reduction and adverse events were documented. Results A total of 4131 patients (52.8% male) with a mean age of 63.0 ± 11.0 years were included. BP was 162.1 ± 14.8/94.7 ± 9.2 mmHg during office visits at baseline. After 10 weeks of candesartan 32 mg/12.5 mg or 25 mg HCTZ, mean BP had lowered to 131.7 ± 10.5/80.0 ± 6.6 mmHg (P good (r = 0.589 for systolic BP and r = 0.389 for diastolic BP during the day). Of those who were normotensive upon OBPM, 35.1% had high ABPM during the day, 49.3% were nondippers, and 3.4% were inverted dippers. Forty-nine adverse events (1.19%) were reported, of which seven (0.17%) were regarded as serious. Conclusion Candesartan 32 mg in a fixed-dose combination with either 12.5 mg or 25 mg HCTZ is safe and effective for further BP lowering irrespective of prior antihypertensive drug class not being able to control BP. PMID:22241950

  3. Results of steel containment vessel model test

    International Nuclear Information System (INIS)

    Luk, V.K.; Ludwigsen, J.S.; Hessheimer, M.F.; Komine, Kuniaki; Matsumoto, Tomoyuki; Costello, J.F.

    1998-05-01

    A series of static overpressurization tests of scale models of nuclear containment structures is being conducted by Sandia National Laboratories for the Nuclear Power Engineering Corporation of Japan and the US Nuclear Regulatory Commission. Two tests are being conducted: (1) a test of a model of a steel containment vessel (SCV) and (2) a test of a model of a prestressed concrete containment vessel (PCCV). This paper summarizes the conduct of the high pressure pneumatic test of the SCV model and the results of that test. Results of this test are summarized and are compared with pretest predictions performed by the sponsoring organizations and others who participated in a blind pretest prediction effort. Questions raised by this comparison are identified and plans for posttest analysis are discussed

  4. Constructing a paleo-DEM in an urban area by the example of the city of Aachen, Germany: Methods and previous results

    Science.gov (United States)

    Pröschel, Bernhard; Lehmkuhl, Frank

    2017-04-01

    Reconstructing paleo-landscapes in urban areas is always a special challenge since the research area often witnessed constant human impact over long time periods. Dense building development is a major difficulty, particularly in regard to accessibility to in-situ soils and archaeological findings. It is therefore necessary to use data from various sources and combine methods from different fields to gain a detailed picture of the former topography. The area, which is occupied by the city of Aachen today, looks back on a long history of human influence. Traces of human activity can be dated back to Neolithic time. The first architectural structures and the first road network were built by the Romans about 2000 years ago. From then on, the area of Aachen was more or less continuously inhabited forming today's city. This long history is represented by archaeological findings throughout the city. Several meters of settlement deposits, covering different eras, are present in many locations. Therefore, it can be assumed that the modern topography significantly differs from the pre-roman topography. The main objective of this project is a reconstruction of the paleo-topography of Aachen in order to gain new insights on the spatial preconditions that the first settlers found. Moreover, further attention is given to the question whether and to what extent a paleo-DEM can help to clarify specific open archaeological and historical questions. The main database for the reconstruction are the archaeological excavation reports of the past 150 years, provided by municipal and regional archives. After analyzing these written accounts, we linked this information to drill data, provided by the Geological Service of North Rhine-Westphalia. Together with additional sources like geological and hydrological maps, we generated a GIS-based terrain model. The result is a high-resolution terrain model, representing the undisturbed pre-roman topography of the inner city of Aachen without any

  5. Office and ambulatory blood pressure control with a fixed-dose combination of candesartan and hydrochlorothiazide in previously uncontrolled hypertensive patients: results of CHILI CU Soon

    Directory of Open Access Journals (Sweden)

    Bramlage P

    2011-12-01

    Full Text Available Thomas Mengden1, Reinhold Hübner2, Peter Bramlage31Kerckhoff-Klinik GmbH, Bad Nauheim, 2Takeda Pharma GmbH, Aachen, 3Institut für Kardiovaskuläre Pharmakologie und Epidemiologie, Mahlow, GermanyBackground: Fixed-dose combinations of candesartan 32 mg and hydrochlorothiazide (HCTZ have been shown to be effective in clinical trials. Upon market entry we conducted a noninterventional study to document the safety and effectiveness of this fixed-dose combination in an unselected population in primary care and to compare blood pressure (BP values obtained during office measurement (OBPM with ambulatory blood pressure measurement (ABPM.Methods: CHILI CU Soon was a prospective, noninterventional, noncontrolled, open-label, multicenter study with a follow-up of at least 10 weeks. High-risk patients aged ≥18 years with previously uncontrolled hypertension were started on candesartan 32 mg in a fixed-dose combination with either 12.5 mg or 25 mg HCTZ. OBPM and ABPM reduction and adverse events were documented.Results: A total of 4131 patients (52.8% male with a mean age of 63.0 ± 11.0 years were included. BP was 162.1 ± 14.8/94.7 ± 9.2 mmHg during office visits at baseline. After 10 weeks of candesartan 32 mg/12.5 mg or 25 mg HCTZ, mean BP had lowered to 131.7 ± 10.5/80.0 ± 6.6 mmHg (P < 0.0001 for both comparisons. BP reduction was comparable irrespective of prior or concomitant medication. In patients for whom physicians regarded an ABPM to be necessary (because of suspected noncontrol over 24 hours, ABP at baseline was 158.2/93.7 mmHg during the day and 141.8/85.2 mmHg during the night. At the last visit, BP had significantly reduced to 133.6/80.0 mmHg and 121.0/72.3 mmHg, respectively, resulting in 20.8% being normotensive over 24 hours (<130/80 mmHg. The correlation between OBPM and ABPM was good (r = 0.589 for systolic BP and r = 0.389 for diastolic BP during the day. Of those who were normotensive upon OBPM, 35.1% had high ABPM during the

  6. The EURAD model: Design and first results

    International Nuclear Information System (INIS)

    1989-01-01

    The contributions are abridged versions of lectures delivered on the occasion of the presentation meeting of the EURAD project on the 20th and 21st of February 1989 in Cologne. EURAD stands for European Acid Deposition Model. The project takes one of the possible and necessary ways to search for scientific answers to the questions which the modifications of the atmosphere caused by anthropogenic influence raise. One of the objectives is to develop a realistic numeric model of long-distance transport of harmful substances in the troposphere over Europe and to use this model for the investigation of pollutant distribution but also for the support of their experimental study. The EURAD Model consists of two parts: a meteorologic mesoscale model and a chemical transport model. In the first part of the presentation, these parts are introduced and questions concerning the implementation of the entire model on the computer system CRAY X-MP/22 discussed. Afterwards it is reported upon the results of the test calculations for the cases 'Chernobyl' and 'Alpex'. Thereafter selected problems concerning the treatments of meteorological and air-chemistry processes as well as the parametrization of subscale processes within the model are discussed. The conclusion is made by two lectures upon emission evaluations and emission scenarios. (orig./KW) [de

  7. A physiological production model for cacao : results of model simulations

    NARCIS (Netherlands)

    Zuidema, P.A.; Leffelaar, P.A.

    2002-01-01

    CASE2 is a physiological model for cocoa (Theobroma cacao L.) growth and yield. This report introduces the CAcao Simulation Engine for water-limited production in a non-technical way and presents simulation results obtained with the model.

  8. Culture Negative Listeria monocytogenes Meningitis Resulting in Hydrocephalus and Severe Neurological Sequelae in a Previously Healthy Immunocompetent Man with Penicillin Allergy

    DEFF Research Database (Denmark)

    Gaini, Shahin; Karlsen, Gunn Hege; Nandy, Anirban

    2015-01-01

    A previously healthy 74-year-old Caucasian man with penicillin allergy was admitted with evolving headache, confusion, fever, and neck stiffness. Treatment for bacterial meningitis with dexamethasone and monotherapy ceftriaxone was started. The cerebrospinal fluid showed negative microscopy...... the catheter. The patient had severe neurological sequelae. This case report emphasises the importance of covering empirically for Listeria monocytogenes in all patients with penicillin allergy with suspected bacterial meningitis. The case also shows that it is possible to have significant infection...

  9. Treatment of Previously Treated Facial Capillary Malformations: Results of Single-Center Retrospective Objective 3-Dimensional Analysis of the Efficacy of Large Spot 532 nm Lasers.

    Science.gov (United States)

    Kwiek, Bartłomiej; Ambroziak, Marcin; Osipowicz, Katarzyna; Kowalewski, Cezary; Rożalski, Michał

    2018-06-01

    Current treatment of facial capillary malformations (CM) has limited efficacy. To assess the efficacy of large spot 532 nm lasers for the treatment of previously treated facial CM with the use of 3-dimensional (3D) image analysis. Forty-three white patients aged 6 to 59 were included in this study. Patients had 3D photography performed before and after treatment with a 532 nm Nd:YAG laser with large spot and contact cooling. Objective analysis of percentage improvement based on 3D digital assessment of combined color and area improvement (global clearance effect [GCE]) were performed. The median maximal improvement achieved during the treatment (GCE) was 59.1%. The mean number of laser procedures required to achieve this improvement was 6.2 (range 1-16). Improvement of minimum 25% (GCE25) was achieved by 88.4% of patients, a minimum of 50% (GCE50) by 61.1%, a minimum of 75% (GCE75) by 25.6%, and a minimum of 90% (GCE90) by 4.6%. Patients previously treated with pulsed dye lasers had a significantly less response than those treated with other modalities (GCE 37.3% vs 61.8%, respectively). A large spot 532 nm laser is effective in previously treated patients with facial CM.

  10. THE INFLUENCE OF THE ASSESSMENT MODEL AND METHOD TOWARD THE SCIENCE LEARNING ACHIEVEMENT BY CONTROLLING THE STUDENTS? PREVIOUS KNOWLEDGE OF MATHEMATICS.

    OpenAIRE

    Adam rumbalifar; I. g. n. Agung; Burhanuddin tola.

    2018-01-01

    This research aims to study the influence of the assessment model and method toward the science learning achievement by controlling the students? previous knowledge of mathematics. This study was conducted at SMP East Seram district with the population of 295 students. This study applied a quasi-experimental method with 2 X 2 factorial design using the ANCOVA model. The findings after controlling the students\\' previous knowledge of mathematics show that the science learning achievement of th...

  11. Modelling rainfall erosion resulting from climate change

    Science.gov (United States)

    Kinnell, Peter

    2016-04-01

    It is well known that soil erosion leads to agricultural productivity decline and contributes to water quality decline. The current widely used models for determining soil erosion for management purposes in agriculture focus on long term (~20 years) average annual soil loss and are not well suited to determining variations that occur over short timespans and as a result of climate change. Soil loss resulting from rainfall erosion is directly dependent on the product of runoff and sediment concentration both of which are likely to be influenced by climate change. This presentation demonstrates the capacity of models like the USLE, USLE-M and WEPP to predict variations in runoff and erosion associated with rainfall events eroding bare fallow plots in the USA with a view to modelling rainfall erosion in areas subject to climate change.

  12. INTRAVAL test case 1b - modelling results

    International Nuclear Information System (INIS)

    Jakob, A.; Hadermann, J.

    1991-07-01

    This report presents results obtained within Phase I of the INTRAVAL study. Six different models are fitted to the results of four infiltration experiments with 233 U tracer on small samples of crystalline bore cores originating from deep drillings in Northern Switzerland. Four of these are dual porosity media models taking into account advection and dispersion in water conducting zones (either tubelike veins or planar fractures), matrix diffusion out of these into pores of the solid phase, and either non-linear or linear sorption of the tracer onto inner surfaces. The remaining two are equivalent porous media models (excluding matrix diffusion) including either non-linear sorption onto surfaces of a single fissure family or linear sorption onto surfaces of several different fissure families. The fits to the experimental data have been carried out by Marquardt-Levenberg procedure yielding error estimates of the parameters, correlation coefficients and also, as a measure for the goodness of the fits, the minimum values of the χ 2 merit function. The effects of different upstream boundary conditions are demonstrated and the penetration depth for matrix diffusion is discussed briefly for both alternative flow path scenarios. The calculations show that the dual porosity media models are significantly more appropriate to the experimental data than the single porosity media concepts. Moreover, it is matrix diffusion rather than the non-linearity of the sorption isotherm which is responsible for the tailing part of the break-through curves. The extracted parameter values for some models for both the linear and non-linear (Freundlich) sorption isotherms are consistent with the results of independent static batch sorption experiments. From the fits, it is generally not possible to discriminate between the two alternative flow path geometries. On the basis of the modelling results, some proposals for further experiments are presented. (author) 15 refs., 23 figs., 7 tabs

  13. Per-Oral Endoscopic Myotomy (POEM) After Previous Laparoscopic Heller Myotomy Is Feasible and Safe in a Porcine Model.

    Science.gov (United States)

    Miles, Luke F; Frelich, Matthew J; Gould, Jon C; Dua, Kulwinder S; Jensen, Eric S; Kastenmeier, Andrew S

    2015-10-01

    We sought to evaluate the feasibility, safety, and difficulty of performing the per-oral endoscopic myotomy (POEM) procedure in the setting of a prior Heller myotomy using a survival porcine model. Four pigs underwent laparoscopic Heller myotomy with Dor partial anterior fundoplication followed by the POEM performed 4 weeks later. Two additional pigs served as controls, undergoing only the POEM. All procedures were completed without complications. The revisional POEM was not significantly more difficult than POEM controls based on procedure time, POEM procedure components, or procedure difficulty scores. Revisional POEM had a longer mean operative time when compared with Heller myotomy (126.0 vs. 83.8 min; PHeller myotomy is safe and feasible in the porcine model and has potential as an option for patients suffering from recurrent or persistent symptoms after failed surgical myotomy.

  14. Drug-Induced QT Prolongation as a Result of an Escitalopram Overdose in a Patient with Previously Undiagnosed Congenital Long QT Syndrome

    Directory of Open Access Journals (Sweden)

    Paul Singh

    2014-01-01

    Full Text Available We present a case of drug-induced QT prolongation caused by an escitalopram overdose in a patient with previously undiagnosed congenital LQTS. A 15-year-old Caucasian female presented following a suicide attempt via an escitalopram overdose. The patient was found to have a prolonged QT interval with episodes of torsades de pointes. The patient was admitted to the telemetry unit and treated. Despite the resolution of the torsades de pointes, she continued to demonstrate a persistently prolonged QT interval. She was seen by the cardiology service and diagnosed with congenital long QT syndrome. This case illustrates the potential for an escitalopram overdose to cause an acute QT prolongation in a patient with congenital LQTS and suggests the importance of a screening electrocardiogram prior to the initiation of SSRIs, especially in patients at high risk for QT prolongation.

  15. Two new prediction rules for spontaneous pregnancy leading to live birth among subfertile couples, based on the synthesis of three previous models.

    NARCIS (Netherlands)

    C.C. Hunault; J.D.F. Habbema (Dik); M.J.C. Eijkemans (René); J.A. Collins (John); J.L.H. Evers (Johannes); E.R. te Velde (Egbert)

    2004-01-01

    textabstractBACKGROUND: Several models have been published for the prediction of spontaneous pregnancy among subfertile patients. The aim of this study was to broaden the empirical basis for these predictions by making a synthesis of three previously published models. METHODS:

  16. Late tamoxifen in patients previously operated for breast cancer without postoperative tamoxifen: 5-year results of a single institution randomised study

    International Nuclear Information System (INIS)

    Veronesi, Andrea; Miolo, GianMaria; Magri, Maria D; Crivellari, Diana; Scalone, Simona; Bidoli, Ettore; Lombardi, Davide

    2010-01-01

    A population of breast cancer patients exists who, for various reasons, never received adjuvant post-operative tamoxifen (TAM). This study was aimed to evaluate the role of late TAM in these patients. From 1997 to 2003, patients aged 35 to 75 years, operated more than 2 years previously for monolateral breast cancer without adjuvant TAM, with no signs of metastases and no contraindication to TAM were randomized to TAM 20 mg/day orally for 2 years or follow-up alone. Events were categorized as locoregional relapse, distant metastases, metachronous breast cancer, tumours other than breast cancer and death from any causes, whichever occurred first. The sample size (197 patients per arm, plus 10% allowance) was based on the assumption of a 30% decrease in the number of events occurring at a rate of 5% annually in the 10 years following randomization. Four hundred and thirty-three patients were randomized in the study (TAM 217, follow-up 216). Patients characteristics (TAM/follow-up) included: median age 55/55 years, median time from surgery 25/25 months (range, 25-288/25-294), in situ carcinoma 18/24, oestrogen receptor (ER) positive in 75/68, negative in 70/57, unknown in 72/91 patients. Previous adjuvant treatment included chemotherapy in 131/120 and an LHRH analogue in 11/13 patients. Thirty-six patients prematurely discontinued TAM after a median of 1 month, mostly because of subjective intolerance. Eighty-three events (TAM 39, follow-up 44) occurred: locoregional relapse in 10/8, distant metastases in 14/16, metachronous breast cancer in 4/10, other tumours in 11/10 patients. Less ER-positive secondary breast cancers occurred in the TAM treated patients than in follow-up patients (1 vs 10, p = 0.005). Event-free survival was similar in both groups of patients. This 5-year analysis revealed significantly less metachronous ER-positive breast cancers in the TAM treated patients. No other statistically significant differences have emerged thus far

  17. Lack of association of variants previously associated with anti-TNF medication response in rheumatoid arthritis patients: results from a homogeneous Greek population.

    Directory of Open Access Journals (Sweden)

    Maria I Zervou

    Full Text Available Treatment strategies blocking tumor necrosis factor (anti-TNF have proven very successful in patients with rheumatoid arthritis (RA, showing beneficial effects in approximately 50-60% of the patients. However, a significant subset of patients does not respond to anti-TNF agents, for reasons that are still unknown. The aim of this study was to validate five single nucleotide polymorphisms (SNPs of PTPRC, CD226, AFF3, MyD88 and CHUK gene loci that have previously been reported to predict anti-TNF outcome. In addition, two markers of RA susceptibility, namely TRAF1/C5 and STAT4 were assessed, in a cohort of anti-TNF-treated RA patients, from the homogeneous Greek island of Crete, Greece. The RA patient cohort consisted of 183 patients treated with either of 3 anti-TNF biologic agents (infliximab, adalimumab and etanercept from the Clinic of Rheumatology of the University Hospital of Crete. The SNPs were genotyped by TaqMan assays or following the Restriction Fragments Length Polymorphisms (RFLPs approach. Disease activity score in 28 joints (DAS28 at baseline and after 6 months were available for all patients and analysis of good versus poor response at 6 months was performed for each SNP. None of the 7 genetic markers correlated with treatment response. We conclude that the gene polymorphisms under investigation are not strongly predictive of anti-TNF response in RA patients from Greece.

  18. Lack of association of variants previously associated with anti-TNF medication response in rheumatoid arthritis patients: results from a homogeneous Greek population.

    Science.gov (United States)

    Zervou, Maria I; Myrthianou, Efsevia; Flouri, Irene; Plant, Darren; Chlouverakis, Gregory; Castro-Giner, Francesc; Rapsomaniki, Panayiota; Barton, Anne; Boumpas, Dimitrios T; Sidiropoulos, Prodromos; Goulielmos, George N

    2013-01-01

    Treatment strategies blocking tumor necrosis factor (anti-TNF) have proven very successful in patients with rheumatoid arthritis (RA), showing beneficial effects in approximately 50-60% of the patients. However, a significant subset of patients does not respond to anti-TNF agents, for reasons that are still unknown. The aim of this study was to validate five single nucleotide polymorphisms (SNPs) of PTPRC, CD226, AFF3, MyD88 and CHUK gene loci that have previously been reported to predict anti-TNF outcome. In addition, two markers of RA susceptibility, namely TRAF1/C5 and STAT4 were assessed, in a cohort of anti-TNF-treated RA patients, from the homogeneous Greek island of Crete, Greece. The RA patient cohort consisted of 183 patients treated with either of 3 anti-TNF biologic agents (infliximab, adalimumab and etanercept) from the Clinic of Rheumatology of the University Hospital of Crete. The SNPs were genotyped by TaqMan assays or following the Restriction Fragments Length Polymorphisms (RFLPs) approach. Disease activity score in 28 joints (DAS28) at baseline and after 6 months were available for all patients and analysis of good versus poor response at 6 months was performed for each SNP. None of the 7 genetic markers correlated with treatment response. We conclude that the gene polymorphisms under investigation are not strongly predictive of anti-TNF response in RA patients from Greece.

  19. Culture Negative Listeria monocytogenes Meningitis Resulting in Hydrocephalus and Severe Neurological Sequelae in a Previously Healthy Immunocompetent Man with Penicillin Allergy

    Directory of Open Access Journals (Sweden)

    Shahin Gaini

    2015-01-01

    Full Text Available A previously healthy 74-year-old Caucasian man with penicillin allergy was admitted with evolving headache, confusion, fever, and neck stiffness. Treatment for bacterial meningitis with dexamethasone and monotherapy ceftriaxone was started. The cerebrospinal fluid showed negative microscopy for bacteria, no bacterial growth, and negative polymerase chain reaction for bacterial DNA. The patient developed hydrocephalus on a second CT scan of the brain on the 5th day of admission. An external ventricular catheter was inserted and Listeria monocytogenes grew in the cerebrospinal fluid from the catheter. The patient had severe neurological sequelae. This case report emphasises the importance of covering empirically for Listeria monocytogenes in all patients with penicillin allergy with suspected bacterial meningitis. The case also shows that it is possible to have significant infection and inflammation even with negative microscopy, negative cultures, and negative broad range polymerase chain reaction in cases of Listeria meningitis. Follow-up spinal taps can be necessary to detect the presence of Listeria monocytogenes.

  20. Discussion of gas trade model (GTM) results

    International Nuclear Information System (INIS)

    Manne, A.

    1989-01-01

    This is in response to your invitation to comment on the structure of GTM and also upon the differences between its results and those of other models participating in EMF9. First a word upon the structure. GTM was originally designed to provide both regional and sectoral detail within the North American market for natural gas at a single point in time, e.g. the year 2000. It is a spatial equilibrium model in which a solution is obtained by maximizing a nonlinear function, the sum of consumers and producers surplus. Since transport costs are included in producers cost, this formulation automatically ensures that geographical price differentials will not differ by more than transport costs. For purposes of EMF9, GTM was modified to allow for resource development and depletion over time

  1. The Danish national passenger modelModel specification and results

    DEFF Research Database (Denmark)

    Rich, Jeppe; Hansen, Christian Overgaard

    2016-01-01

    The paper describes the structure of the new Danish National Passenger model and provides on this basis a general discussion of large-scale model design, cost-damping and model validation. The paper aims at providing three main contributions to the existing literature. Firstly, at the general level......, the paper provides a description of a large-scale forecast model with a discussion of the linkage between population synthesis, demand and assignment. Secondly, the paper gives specific attention to model specification and in particular choice of functional form and cost-damping. Specifically we suggest...... a family of logarithmic spline functions and illustrate how it is applied in the model. Thirdly and finally, we evaluate model sensitivity and performance by evaluating the distance distribution and elasticities. In the paper we present results where the spline-function is compared with more traditional...

  2. Superconducting solenoid model magnet test results

    Energy Technology Data Exchange (ETDEWEB)

    Carcagno, R.; Dimarco, J.; Feher, S.; Ginsburg, C.M.; Hess, C.; Kashikhin, V.V.; Orris, D.F.; Pischalnikov, Y.; Sylvester, C.; Tartaglia, M.A.; Terechkine, I.; /Fermilab

    2006-08-01

    Superconducting solenoid magnets suitable for the room temperature front end of the Fermilab High Intensity Neutrino Source (formerly known as Proton Driver), an 8 GeV superconducting H- linac, have been designed and fabricated at Fermilab, and tested in the Fermilab Magnet Test Facility. We report here results of studies on the first model magnets in this program, including the mechanical properties during fabrication and testing in liquid helium at 4.2 K, quench performance, and magnetic field measurements. We also describe new test facility systems and instrumentation that have been developed to accomplish these tests.

  3. Superconducting solenoid model magnet test results

    International Nuclear Information System (INIS)

    Carcagno, R.; Dimarco, J.; Feher, S.; Ginsburg, C.M.; Hess, C.; Kashikhin, V.V.; Orris, D.F.; Pischalnikov, Y.; Sylvester, C.; Tartaglia, M.A.; Terechkine, I.; Tompkins, J.C.; Wokas, T.; Fermilab

    2006-01-01

    Superconducting solenoid magnets suitable for the room temperature front end of the Fermilab High Intensity Neutrino Source (formerly known as Proton Driver), an 8 GeV superconducting H- linac, have been designed and fabricated at Fermilab, and tested in the Fermilab Magnet Test Facility. We report here results of studies on the first model magnets in this program, including the mechanical properties during fabrication and testing in liquid helium at 4.2 K, quench performance, and magnetic field measurements. We also describe new test facility systems and instrumentation that have been developed to accomplish these tests

  4. Can GSTM1 and GSTT1 polymorphisms predict clinical outcomes of chemotherapy in gastric and colorectal cancers? A result based on the previous reports

    Directory of Open Access Journals (Sweden)

    Liu H

    2016-06-01

    Full Text Available Haixia Liu,1,* Wei Shi,2,* Lianli Zhao,3 Dianlu Dai,4 Jinghua Gao,5 Xiangjun Kong6 1Department of Ultrasound, 2Office of Medical Statistics, 3Human Resource Department, 4Department of Surgical Oncology, 5Department of Medical Oncology, 6Central Laboratory, Cangzhou Central Hospital, Yunhe District, Cangzhou, People’s Republic of China *These authors contributed equally to this study and should be considered cofirst authors Background: Gastric and colorectal cancers remain the major causes of cancer-related death. Although chemotherapy improves the prognosis of the patients with gastrointestinal cancers, some patients do not benefit from therapy and are exposed to the adverse effects. The polymorphisms in genes including GSTM1 and GSTT1 have been explored to predict therapeutic efficacy; however, the results were inconsistent and inconclusive. Materials and methods: A systematic review and meta-analysis was performed by searching relevant studies about the association between the GSTM1 and GSTT1 polymorphisms and chemotherapy efficacy in gastrointestinal cancers in databases such as PubMed, EMBASE, Web of Science, Chinese National Knowledge Infrastructure, and Wanfang database up to January 10, 2016. Subgroup analyses were also performed according to ethnicity, cancer type, evaluation criteria, study type, chemotherapy type, and age. Results: A total of 19 articles containing 3,217 cases were finally included. Overall analysis suggested that no significance was found between overall toxicity, neurotoxicity, neutropenia, gastrointestinal toxicity, tumor response, and progression-free survival, and the polymorphisms in GSTM1 and GSTT1, while GSTM1 polymorphism associated with overall survival (OS; hazard ratio =1.213, 95% confidence interval =1.060–1.388, P=0.005. Subgroup analyses suggested that neurotoxicity was associated with GSTM1 polymorphism in the Asian population, neutropenia was associated with GSTM1 polymorphism in palliative

  5. Contamination of the Alluvium of the Nitra River in Slovakia by Cadmium, Mercury and Lead as a Result of Previous Intense Industrial Activity.

    Science.gov (United States)

    Vollmannova, A; Kujovsky, M; Stanovic, R; Arvay, J; Harangozo, L

    2016-10-01

    The Nitra river is one of the most polluted rivers in the Slovak Republic. The aim of the study was to estimate the risk of Cd, Pb and Hg contamination of riverside sediments and alluvial soil in the vicinity of the Nitra river. The pseudototal Cd (all Cd forms except for residual fraction) and total Hg contents in riverside sediments (0.74-1.88 and 0.06-5.44 mg/kg, respectively) exceeded the limits for Cd and Hg in sandy soils (0.4 and 0.15 mg/kg). In three chosen localities in the flood plain of the Nitra river the soil content of mobile Pb forms (0.10-0.32 mg/kg), the pseudototal Cd (0.25-2.52 mg/kg) and total Hg content (0.03-1.6 mg/kg) exceeded the limits for Pb, Cd and Hg in loamy soils (0.1, 0.7 and 0.5 mg/kg, respectively). The obtained results confirmed the risk of Pb, Cd, Hg contamination caused by industrial activity in the vicinity of the Nitra river.

  6. Scale Model Thruster Acoustic Measurement Results

    Science.gov (United States)

    Vargas, Magda; Kenny, R. Jeremy

    2013-01-01

    The Space Launch System (SLS) Scale Model Acoustic Test (SMAT) is a 5% scale representation of the SLS vehicle, mobile launcher, tower, and launch pad trench. The SLS launch propulsion system will be comprised of the Rocket Assisted Take-Off (RATO) motors representing the solid boosters and 4 Gas Hydrogen (GH2) thrusters representing the core engines. The GH2 thrusters were tested in a horizontal configuration in order to characterize their performance. In Phase 1, a single thruster was fired to determine the engine performance parameters necessary for scaling a single engine. A cluster configuration, consisting of the 4 thrusters, was tested in Phase 2 to integrate the system and determine their combined performance. Acoustic and overpressure data was collected during both test phases in order to characterize the system's acoustic performance. The results from the single thruster and 4- thuster system are discussed and compared.

  7. CMS standard model Higgs boson results

    Directory of Open Access Journals (Sweden)

    Garcia-Abia Pablo

    2013-11-01

    Full Text Available In July 2012 CMS announced the discovery of a new boson with properties resembling those of the long-sought Higgs boson. The analysis of the proton-proton collision data recorded by the CMS detector at the LHC, corresponding to integrated luminosities of 5.1 fb−1 at √s = 7 TeV and 19.6 fb−1 at √s = 8 TeV, confirm the Higgs-like nature of the new boson, with a signal strength associated with vector bosons and fermions consistent with the expectations for a standard model (SM Higgs boson, and spin-parity clearly favouring the scalar nature of the new boson. In this note I review the updated results of the CMS experiment.

  8. Modelling Extortion Racket Systems: Preliminary Results

    Science.gov (United States)

    Nardin, Luis G.; Andrighetto, Giulia; Székely, Áron; Conte, Rosaria

    Mafias are highly powerful and deeply entrenched organised criminal groups that cause both economic and social damage. Overcoming, or at least limiting, their harmful effects is a societally beneficial objective, which renders its dynamics understanding an objective of both scientific and political interests. We propose an agent-based simulation model aimed at understanding how independent and combined effects of legal and social norm-based processes help to counter mafias. Our results show that legal processes are effective in directly countering mafias by reducing their activities and changing the behaviour of the rest of population, yet they are not able to change people's mind-set that renders the change fragile. When combined with social norm-based processes, however, people's mind-set shifts towards a culture of legality rendering the observed behaviour resilient to change.

  9. New results in the Dual Parton Model

    International Nuclear Information System (INIS)

    Van, J.T.T.; Capella, A.

    1984-01-01

    In this paper, the similarity between the x distribution for particle production and the fragmentation functions are observed in e+e- collisions and in deep inelastic scattering are presented. Based on the observation, the authors develop a complete approach to multiparticle production which incorporates the most important features and concepts learned about high energy collisions. 1. Topological expansion : the dominant diagram at high energy corresponds to the simplest topology. 2. Unitarity : diagrams of various topology contribute to the cross sections in a way that unitary is preserved. 3. Regge behaviour and Duality. 4. Partonic structure of hadrons. These general theoretical ideas, result from many joint experimental and theoretical efforts on the study of soft hadron physics. The dual parton model is able to explain all the experimental features from FNAL to SPS collider energies. It has all the properties of an S-matrix theory and provides a unified description of hadron-hadron, hadron-nucleus and nucleus-nucleus collisions

  10. Results From the Phase III Randomized Trial of Onartuzumab Plus Erlotinib Versus Erlotinib in Previously Treated Stage IIIB or IV Non-Small-Cell Lung Cancer: METLung.

    Science.gov (United States)

    Spigel, David R; Edelman, Martin J; O'Byrne, Kenneth; Paz-Ares, Luis; Mocci, Simonetta; Phan, See; Shames, David S; Smith, Dustin; Yu, Wei; Paton, Virginia E; Mok, Tony

    2017-02-01

    Purpose The phase III OAM4971g study (METLung) examined the efficacy and safety of onartuzumab plus erlotinib in patients with locally advanced or metastatic non-small-cell lung cancer selected by MET immunohistochemistry whose disease had progressed after treatment with a platinum-based chemotherapy regimen. Patients and Methods Patients were randomly assigned at a one-to-one ratio to receive onartuzumab (15 mg/kg intravenously on day 1 of each 21-day cycle) plus daily oral erlotinib 150 mg or intravenous placebo plus daily oral erlotinib 150 mg. The primary end point was overall survival (OS) in the intent-to-treat population. Secondary end points included median progression-free survival, overall response rate, biomarker analysis, and safety. Results A total of 499 patients were enrolled (onartuzumab, n = 250; placebo, n = 249). Median OS was 6.8 versus 9.1 months for onartuzumab versus placebo (stratified hazard ratio [HR], 1.27; 95% CI, 0.98 to 1.65; P = .067), with a greater number of deaths in the onartuzumab arm (130 [52%] v 114 [46%]). Median progression-free survival was 2.7 versus 2.6 months (stratified HR, 0.99; 95% CI, 0.81 to 1.20; P = .92), and overall response rate was 8.4% and 9.6% for onartuzumab versus placebo, respectively. Exploratory analyses using MET fluorescence in situ hybridization status and gene expression showed no benefit for onartuzumab; patients with EGFR mutations showed a trend toward shorter OS with onartuzumab treatment (HR, 4.68; 95% CI, 0.97 to 22.63). Grade 3 to 5 adverse events were reported by 56.0% and 51.2% of patients, with serious AEs in 33.9% and 30.7%, for experimental versus control arms, respectively. Conclusion Onartuzumab plus erlotinib did not improve clinical outcomes, with shorter OS in the onartuzumab arm, compared with erlotinib in patients with MET-positive non-small-cell lung cancer.

  11. Evidence of previous but not current transmission of chikungunya virus in southern and central Vietnam: Results from a systematic review and a seroprevalence study in four locations.

    Directory of Open Access Journals (Sweden)

    Tran Minh Quan

    2018-02-01

    Full Text Available Arbovirus infections are a serious concern in tropical countries due to their high levels of transmission and morbidity. With the outbreaks of chikungunya (CHIKV in surrounding regions in recent years and the fact that the environment in Vietnam is suitable for the vectors of CHIKV, the possibility of transmission of CHIKV in Vietnam is of great interest. However, information about CHIKV activity in Vietnam remains limited.In order to address this question, we performed a systematic review of CHIKV in Vietnam and a CHIKV seroprevalence survey. The seroprevalence survey tested for CHIKV IgG in population serum samples from individuals of all ages in 2015 from four locations in Vietnam.The four locations were An Giang province (n = 137, Ho Chi Minh City (n = 136, Dak Lak province (n = 137, and Hue City (n = 136. The findings give us evidence of some CHIKV activity: 73/546 of overall samples were seropositive (13.4%. The age-adjusted seroprevalences were 12.30% (6.58-18.02, 13.42% (7.16-19.68, 7.97% (3.56-12.38, and 3.72% (1.75-5.69 in An Giang province, Ho Chi Minh City, Dak Lak province, and Hue City respectively. However, the age-stratified seroprevalence suggests that the last transmission ended around 30 years ago, consistent with results from the systematic review. We see no evidence for on-going transmission in three of the locations, though with some evidence of recent exposure in Dak Lak, most likely due to transmission in neighbouring countries. Before the 1980s, when transmission was occurring, we estimate on average 2-4% of the population were infected each year in HCMC and An Giang and Hue (though transmision ended earlier in Hue. We estimate lower transmission in Dak Lak, with around 1% of the population infected each year.In conclusion, we find evidence of past CHIKV transmission in central and southern Vietnam, but no evidence of recent sustained transmission. When transmission of CHIKV did occur, it appeared to be widespread and

  12. Finiteness results for Abelian tree models

    NARCIS (Netherlands)

    Draisma, J.; Eggermont, R.H.

    2015-01-01

    Equivariant tree models are statistical models used in the reconstruction of phylogenetic trees from genetic data. Here equivariant refers to a symmetry group imposed on the root distribution and on the transition matrices in the model. We prove that if that symmetry group is Abelian, then the

  13. Finiteness results for Abelian tree models

    NARCIS (Netherlands)

    Draisma, J.; Eggermont, R.H.

    2012-01-01

    Equivariant tree models are statistical models used in the reconstruction of phylogenetic trees from genetic data. Here equivariant refers to a symmetry group imposed on the root distribution and on the transition matrices in the model. We prove that if that symmetry group is Abelian, then the

  14. Finiteness results for Abelian tree models

    NARCIS (Netherlands)

    Draisma, J.; Eggermont, R.H.

    2015-01-01

    Equivariant tree models are statistical models used in the reconstruction of phylogenetic trees from genetic data. Here equivariant§ refers to a symmetry group imposed on the root distribution and on the transition matrices in the model. We prove that if that symmetry group is Abelian, then the

  15. Immersive visualization of dynamic CFD model results

    International Nuclear Information System (INIS)

    Comparato, J.R.; Ringel, K.L.; Heath, D.J.

    2004-01-01

    With immersive visualization the engineer has the means for vividly understanding problem causes and discovering opportunities to improve design. Software can generate an interactive world in which collaborators experience the results of complex mathematical simulations such as computational fluid dynamic (CFD) modeling. Such software, while providing unique benefits over traditional visualization techniques, presents special development challenges. The visualization of large quantities of data interactively requires both significant computational power and shrewd data management. On the computational front, commodity hardware is outperforming large workstations in graphical quality and frame rates. Also, 64-bit commodity computing shows promise in enabling interactive visualization of large datasets. Initial interactive transient visualization methods and examples are presented, as well as development trends in commodity hardware and clustering. Interactive, immersive visualization relies on relevant data being stored in active memory for fast response to user requests. For large or transient datasets, data management becomes a key issue. Techniques for dynamic data loading and data reduction are presented as means to increase visualization performance. (author)

  16. Linkage of PRA models. Phase 1, Results

    Energy Technology Data Exchange (ETDEWEB)

    Smith, C.L.; Knudsen, J.K.; Kelly, D.L.

    1995-12-01

    The goal of the Phase I work of the ``Linkage of PRA Models`` project was to postulate methods of providing guidance for US Nuclear Regulator Commission (NRC) personnel on the selection and usage of probabilistic risk assessment (PRA) models that are best suited to the analysis they are performing. In particular, methods and associated features are provided for (a) the selection of an appropriate PRA model for a particular analysis, (b) complementary evaluation tools for the analysis, and (c) a PRA model cross-referencing method. As part of this work, three areas adjoining ``linking`` analyses to PRA models were investigated: (a) the PRA models that are currently available, (b) the various types of analyses that are performed within the NRC, and (c) the difficulty in trying to provide a ``generic`` classification scheme to groups plants based upon a particular plant attribute.

  17. Linkage of PRA models. Phase 1, Results

    International Nuclear Information System (INIS)

    Smith, C.L.; Knudsen, J.K.; Kelly, D.L.

    1995-12-01

    The goal of the Phase I work of the ''Linkage of PRA Models'' project was to postulate methods of providing guidance for US Nuclear Regulator Commission (NRC) personnel on the selection and usage of probabilistic risk assessment (PRA) models that are best suited to the analysis they are performing. In particular, methods and associated features are provided for (a) the selection of an appropriate PRA model for a particular analysis, (b) complementary evaluation tools for the analysis, and (c) a PRA model cross-referencing method. As part of this work, three areas adjoining ''linking'' analyses to PRA models were investigated: (a) the PRA models that are currently available, (b) the various types of analyses that are performed within the NRC, and (c) the difficulty in trying to provide a ''generic'' classification scheme to groups plants based upon a particular plant attribute

  18. Engineering Glass Passivation Layers -Model Results

    Energy Technology Data Exchange (ETDEWEB)

    Skorski, Daniel C.; Ryan, Joseph V.; Strachan, Denis M.; Lepry, William C.

    2011-08-08

    The immobilization of radioactive waste into glass waste forms is a baseline process of nuclear waste management not only in the United States, but worldwide. The rate of radionuclide release from these glasses is a critical measure of the quality of the waste form. Over long-term tests and using extrapolations of ancient analogues, it has been shown that well designed glasses exhibit a dissolution rate that quickly decreases to a slow residual rate for the lifetime of the glass. The mechanistic cause of this decreased corrosion rate is a subject of debate, with one of the major theories suggesting that the decrease is caused by the formation of corrosion products in such a manner as to present a diffusion barrier on the surface of the glass. Although there is much evidence of this type of mechanism, there has been no attempt to engineer the effect to maximize the passivating qualities of the corrosion products. This study represents the first attempt to engineer the creation of passivating phases on the surface of glasses. Our approach utilizes interactions between the dissolving glass and elements from the disposal environment to create impermeable capping layers. By drawing from other corrosion studies in areas where passivation layers have been successfully engineered to protect the bulk material, we present here a report on mineral phases that are likely have a morphological tendency to encrust the surface of the glass. Our modeling has focused on using the AFCI glass system in a carbonate, sulfate, and phosphate rich environment. We evaluate the minerals predicted to form to determine the likelihood of the formation of a protective layer on the surface of the glass. We have also modeled individual ions in solutions vs. pH and the addition of aluminum and silicon. These results allow us to understand the pH and ion concentration dependence of mineral formation. We have determined that iron minerals are likely to form a complete incrustation layer and we plan

  19. CIEMAT model results for Esthwaite Water

    International Nuclear Information System (INIS)

    Aguero, A.; Garcia-Olivares, A.

    2000-01-01

    This study used the transfer model PRYMA-LO, developed by CIEMAT-IMA, Madrid, Spain, to simulate the transfer of Cs-137 in watershed scenarios. The main processes considered by the model include: transfer of the fallout to the ground, incorporation of the fallout radioisotopes into the water flow, and their removal from the system. The model was tested against observation data obtained in water and sediments of Esthwaite Water, Lake District, UK. This comparison made it possible to calibrate the parameters of the model to the specific scenario

  20. Flying Training Capacity Model: Initial Results

    National Research Council Canada - National Science Library

    Lynch, Susan

    2005-01-01

    OBJECTIVE: (1) Determine the flying training capacity for 6 bases: * Sheppard AFB * Randolph AFB * Moody AFB * Columbus AFB * Laughlin AFB * Vance AFB * (2) Develop versatile flying training capacity simulation model for AETC...

  1. Graphical interpretation of numerical model results

    International Nuclear Information System (INIS)

    Drewes, D.R.

    1979-01-01

    Computer software has been developed to produce high quality graphical displays of data from a numerical grid model. The code uses an existing graphical display package (DISSPLA) and overcomes some of the problems of both line-printer output and traditional graphics. The software has been designed to be flexible enough to handle arbitrarily placed computation grids and a variety of display requirements

  2. Ignalina NPP Safety Analysis: Models and Results

    International Nuclear Information System (INIS)

    Uspuras, E.

    1999-01-01

    Research directions, linked to safety assessment of the Ignalina NPP, of the scientific safety analysis group are presented: Thermal-hydraulic analysis of accidents and operational transients; Thermal-hydraulic assessment of Ignalina NPP Accident Localization System and other compartments; Structural analysis of plant components, piping and other parts of Main Circulation Circuit; Assessment of RBMK-1500 reactor core and other. Models and main works carried out last year are described. (author)

  3. Meteorological Uncertainty of atmospheric Dispersion model results (MUD)

    DEFF Research Database (Denmark)

    Havskov Sørensen, Jens; Amstrup, Bjarne; Feddersen, Henrik

    The MUD project addresses assessment of uncertainties of atmospheric dispersion model predictions, as well as optimum presentation to decision makers. Previously, it has not been possible to estimate such uncertainties quantitatively, but merely to calculate the 'most likely' dispersion scenario....

  4. Meteorological uncertainty of atmospheric dispersion model results (MUD)

    Energy Technology Data Exchange (ETDEWEB)

    Havskov Soerensen, J.; Amstrup, B.; Feddersen, H. [Danish Meteorological Institute, Copenhagen (Denmark)] [and others

    2013-08-15

    The MUD project addresses assessment of uncertainties of atmospheric dispersion model predictions, as well as possibilities for optimum presentation to decision makers. Previously, it has not been possible to estimate such uncertainties quantitatively, but merely to calculate the 'most likely' dispersion scenario. However, recent developments in numerical weather prediction (NWP) include probabilistic forecasting techniques, which can be utilised also for long-range atmospheric dispersion models. The ensemble statistical methods developed and applied to NWP models aim at describing the inherent uncertainties of the meteorological model results. These uncertainties stem from e.g. limits in meteorological observations used to initialise meteorological forecast series. By perturbing e.g. the initial state of an NWP model run in agreement with the available observational data, an ensemble of meteorological forecasts is produced from which uncertainties in the various meteorological parameters are estimated, e.g. probabilities for rain. Corresponding ensembles of atmospheric dispersion can now be computed from which uncertainties of predicted radionuclide concentration and deposition patterns can be derived. (Author)

  5. Meteorological uncertainty of atmospheric dispersion model results (MUD)

    International Nuclear Information System (INIS)

    Havskov Soerensen, J.; Amstrup, B.; Feddersen, H.

    2013-08-01

    The MUD project addresses assessment of uncertainties of atmospheric dispersion model predictions, as well as possibilities for optimum presentation to decision makers. Previously, it has not been possible to estimate such uncertainties quantitatively, but merely to calculate the 'most likely' dispersion scenario. However, recent developments in numerical weather prediction (NWP) include probabilistic forecasting techniques, which can be utilised also for long-range atmospheric dispersion models. The ensemble statistical methods developed and applied to NWP models aim at describing the inherent uncertainties of the meteorological model results. These uncertainties stem from e.g. limits in meteorological observations used to initialise meteorological forecast series. By perturbing e.g. the initial state of an NWP model run in agreement with the available observational data, an ensemble of meteorological forecasts is produced from which uncertainties in the various meteorological parameters are estimated, e.g. probabilities for rain. Corresponding ensembles of atmospheric dispersion can now be computed from which uncertainties of predicted radionuclide concentration and deposition patterns can be derived. (Author)

  6. Microplasticity of MMC. Experimental results and modelling

    International Nuclear Information System (INIS)

    Maire, E.; Lormand, G.; Gobin, P.F.; Fougeres, R.

    1993-01-01

    The microplastic behavior of several MMC is investigated by means of tension and compression tests. This behavior is assymetric : the proportional limit is higher in tension than in compression but the work hardening rate is higher in compression. These differences are analysed in terms of maxium of the Tresca's shear stress at the interface (proportional limit) and of the emission of dislocation loops during the cooling (work hardening rate). On another hand, a model is proposed to calculate the value of the yield stress, describing the composite as a material composed of three phases : inclusion, unaffected matrix and matrix surrounding the inclusion having a gradient in the density of the thermally induced dilocations. (orig.)

  7. Microplasticity of MMC. Experimental results and modelling

    Energy Technology Data Exchange (ETDEWEB)

    Maire, E. (Groupe d' Etude de Metallurgie Physique et de Physique des Materiaux, INSA, 69 Villeurbanne (France)); Lormand, G. (Groupe d' Etude de Metallurgie Physique et de Physique des Materiaux, INSA, 69 Villeurbanne (France)); Gobin, P.F. (Groupe d' Etude de Metallurgie Physique et de Physique des Materiaux, INSA, 69 Villeurbanne (France)); Fougeres, R. (Groupe d' Etude de Metallurgie Physique et de Physique des Materiaux, INSA, 69 Villeurbanne (France))

    1993-11-01

    The microplastic behavior of several MMC is investigated by means of tension and compression tests. This behavior is assymetric : the proportional limit is higher in tension than in compression but the work hardening rate is higher in compression. These differences are analysed in terms of maxium of the Tresca's shear stress at the interface (proportional limit) and of the emission of dislocation loops during the cooling (work hardening rate). On another hand, a model is proposed to calculate the value of the yield stress, describing the composite as a material composed of three phases : inclusion, unaffected matrix and matrix surrounding the inclusion having a gradient in the density of the thermally induced dilocations. (orig.).

  8. Dermal uptake of phthalates from clothing: Comparison of model to human participant results

    DEFF Research Database (Denmark)

    Morrison, G. C.; Weschler, Charles J.; Beko, G.

    2017-01-01

    In this research, we extend a model of transdermal uptake of phthalates to include a layer of clothing. When compared with experimental results, this model better estimates dermal uptake of diethylphthalate and di-n-butylphthalate (DnBP) than a previous model. The model predictions are consistent...

  9. Interpreting "Personality" Taxonomies: Why Previous Models Cannot Capture Individual-Specific Experiencing, Behaviour, Functioning and Development. Major Taxonomic Tasks Still Lay Ahead.

    Science.gov (United States)

    Uher, Jana

    2015-12-01

    As science seeks to make generalisations, a science of individual peculiarities encounters intricate challenges. This article explores these challenges by applying the Transdisciplinary Philosophy-of-Science Paradigm for Research on Individuals (TPS-Paradigm) and by exploring taxonomic "personality" research as an example. Analyses of researchers' interpretations of the taxonomic "personality" models, constructs and data that have been generated in the field reveal widespread erroneous assumptions about the abilities of previous methodologies to appropriately represent individual-specificity in the targeted phenomena. These assumptions, rooted in everyday thinking, fail to consider that individual-specificity and others' minds cannot be directly perceived, that abstract descriptions cannot serve as causal explanations, that between-individual structures cannot be isomorphic to within-individual structures, and that knowledge of compositional structures cannot explain the process structures of their functioning and development. These erroneous assumptions and serious methodological deficiencies in widely used standardised questionnaires have effectively prevented psychologists from establishing taxonomies that can comprehensively model individual-specificity in most of the kinds of phenomena explored as "personality", especially in experiencing and behaviour and in individuals' functioning and development. Contrary to previous assumptions, it is not universal models but rather different kinds of taxonomic models that are required for each of the different kinds of phenomena, variations and structures that are commonly conceived of as "personality". Consequently, to comprehensively explore individual-specificity, researchers have to apply a portfolio of complementary methodologies and develop different kinds of taxonomies, most of which have yet to be developed. Closing, the article derives some meta-desiderata for future research on individuals' "personality".

  10. Allometric Models to Predict Aboveground Woody Biomass of Black Locust (Robinia pseudoacacia L. in Short Rotation Coppice in Previous Mining and Agricultural Areas in Germany

    Directory of Open Access Journals (Sweden)

    Christin Carl

    2017-09-01

    Full Text Available Black locust is a drought-resistant tree species with high biomass productivity during juvenility; it is able to thrive on wastelands, such as former brown coal fields and dry agricultural areas. However, research conducted on this species in such areas is limited. This paper aims to provide a basis for predicting tree woody biomass for black locust based on tree, competition, and site variables at 14 sites in northeast Germany that were previously utilized for mining or agriculture. The study areas, which are located in an area covering 320 km × 280 km, are characterized by a variety of climatic and soil conditions. Influential variables, including tree parameters, competition, and climatic parameters were considered. Allometric biomass models were employed. The findings show that the most important parameters are tree and competition variables. Different former land utilizations, such as mining or agriculture, as well as growth by cores or stumps, significantly influenced aboveground woody biomass production. The new biomass models developed as part of this study can be applied to calculate woody biomass production and carbon sequestration of Robinia pseudoacacia L. in short rotation coppices in previous mining and agricultural areas.

  11. Laparoscopy After Previous Laparotomy

    Directory of Open Access Journals (Sweden)

    Zulfo Godinjak

    2006-11-01

    Full Text Available Following the abdominal surgery, extensive adhesions often occur and they can cause difficulties during laparoscopic operations. However, previous laparotomy is not considered to be a contraindication for laparoscopy. The aim of this study is to present that an insertion of Veres needle in the region of umbilicus is a safe method for creating a pneumoperitoneum for laparoscopic operations after previous laparotomy. In the last three years, we have performed 144 laparoscopic operations in patients that previously underwent one or two laparotomies. Pathology of digestive system, genital organs, Cesarean Section or abdominal war injuries were the most common causes of previouslaparotomy. During those operations or during entering into abdominal cavity we have not experienced any complications, while in 7 patients we performed conversion to laparotomy following the diagnostic laparoscopy. In all patients an insertion of Veres needle and trocar insertion in the umbilical region was performed, namely a technique of closed laparoscopy. Not even in one patient adhesions in the region of umbilicus were found, and no abdominal organs were injured.

  12. Modelling of near-field radionuclide transport phenomena in a KBS-3V type of repository for nuclear waste with Goldsim Code - and verification against previous methods

    International Nuclear Information System (INIS)

    Pulkkanen, V.-M.; Nordman, H.

    2010-03-01

    Traditional radionuclide transport models overestimate significantly some phenomena, or completely ignore them. This motivates the development of new more precise models. As a result, this work is a description of commissioning of a new KBS-3V near-field radionuclide transport model, which has been done with a commercial software called GoldSim. According to earlier models, GoldSim model uses rz coordinates, but the solubilities of radionuclides have been treated more precisely. To begin with, the physical phenomena concerning near-field transport have been introduced according to GoldSim way of thinking. Also, the computational methods of GoldSim have been introduced and compared to methods used earlier. The actual verification of GoldSim model has been carried out by comparing the GoldSim results from simple cases to the corresponding results obtained with REPCOM, a software developed by VTT and used in several safety assessments. The results agree well. Finally, a few complicated cases were studied. In these cases, the REPCOM's limitations in handling of some phenomena become evident. The differences in the results are caused especially by the extension of the solubility limit to the whole computational domain, and the element-wise treatment of the solubilities which was used instead of nuclide-wise treatment. This work has been carried out as a special assignment to the former laboratory of Advanced Energy Systems in Helsinki University of Technology. The work was done at VTT. (orig.)

  13. Golimumab in patients with active rheumatoid arthritis who have previous experience with tumour necrosis factor inhibitors: results of a long-term extension of the randomised, double-blind, placebo-controlled GO-AFTER study through week 160

    NARCIS (Netherlands)

    Smolen, Josef S.; Kay, Jonathan; Landewé, Robert B. M.; Matteson, Eric L.; Gaylis, Norman; Wollenhaupt, Jurgen; Murphy, Frederick T.; Zhou, Yiying; Hsia, Elizabeth C.; Doyle, Mittie K.

    2012-01-01

    The aim of this study was to assess long-term golimumab therapy in patients with rheumatoid arthritis (RA) who discontinued previous tumour necrosis factor alpha (TNFα) inhibitor(s) for any reason. Results through week 24 of this multicentre, randomised, double-blind, placebo-controlled study of

  14. Results and Error Estimates from GRACE Forward Modeling over Antarctica

    Science.gov (United States)

    Bonin, Jennifer; Chambers, Don

    2013-04-01

    Forward modeling using a weighted least squares technique allows GRACE information to be projected onto a pre-determined collection of local basins. This decreases the impact of spatial leakage, allowing estimates of mass change to be better localized. The technique is especially valuable where models of current-day mass change are poor, such as over Antarctica. However when tested previously, the least squares technique has required constraints in the form of added process noise in order to be reliable. Poor choice of local basin layout has also adversely affected results, as has the choice of spatial smoothing used with GRACE. To develop design parameters which will result in correct high-resolution mass detection and to estimate the systematic errors of the method over Antarctica, we use a "truth" simulation of the Antarctic signal. We apply the optimal parameters found from the simulation to RL05 GRACE data across Antarctica and the surrounding ocean. We particularly focus on separating the Antarctic peninsula's mass signal from that of the rest of western Antarctica. Additionally, we characterize how well the technique works for removing land leakage signal from the nearby ocean, particularly that near the Drake Passage.

  15. Some exact results for the three-layer Zamolodchikov model

    International Nuclear Information System (INIS)

    Boos, H.E.; Mangazeev, V.V.

    2001-01-01

    In this paper we continue the study of the three-layer Zamolodchikov model started in our previous works (H.E. Boos, V.V. Mangazeev, J. Phys. A 32 (1999) 3041-3054 and H.E. Boos, V.V. Mangazeev, J. Phys. A 32 (1999) 5285-5298). We analyse numerically the solutions to the Bethe ansatz equations obtained in H.E. Boos, V.V. Mangazeev, J. Phys. A 32 (1999) 5285-5298. We consider two regimes I and II which differ by the signs of the spherical sides (a 1 ,a 2 ,a 3 )→(-a 1 ,-a 2 ,-a 3 ). We accept the two-line hypothesis for the regime I and the one-line hypothesis for the regime II. In the thermodynamic limit we derive integral equations for distribution densities and solve them exactly. We calculate the partition function for the three-layer Zamolodchikov model and check a compatibility of this result with the functional relations obtained in H.E. Boos, V.V. Mangazeev, J. Phys. A 32 (1999) 5285-5298. We also do some numeric checkings of our results

  16. First Results of Modeling Radiation Belt Electron Dynamics with the SAMI3 Plasmasphere Model

    Science.gov (United States)

    Komar, C. M.; Glocer, A.; Huba, J.; Fok, M. C. H.; Kang, S. B.; Buzulukova, N.

    2017-12-01

    The radiation belts were one of the first discoveries of the Space Age some sixty years ago and radiation belt models have been improving since the discovery of the radiation belts. The plasmasphere is one region that has been critically important to determining the dynamics of radiation belt populations. This region of space plays a critical role in describing the distribution of chorus and magnetospheric hiss waves throughout the inner magnetosphere. Both of these waves have been shown to interact with energetic electrons in the radiation belts and can result in the energization or loss of radiation belt electrons. However, radiation belt models have been historically limited in describing the distribution of cold plasmaspheric plasma and have relied on empirically determined plasmasphere models. Some plasmasphere models use an azimuthally symmetric distribution of the plasmasphere which can fail to capture important plasmaspheric dynamics such as the development of plasmaspheric drainage plumes. Previous work have coupled the kinetic bounce-averaged Comprehensive Inner Magnetosphere-Ionosphere (CIMI) model used to model ring current and radiation belt populations with the Block-adaptive Tree Solar wind Roe-type Upwind Scheme (BATSRUS) global magnetohydrodynamic model to self-consistently obtain the magnetospheric magnetic field and ionospheric potential. The present work will utilize this previous coupling and will additionally couple the SAMI3 plasmasphere model to better represent the dynamics on the plasmasphere and its role in determining the distribution of waves throughout the inner magnetosphere. First results on the relevance of chorus, hiss, and ultralow frequency waves on radiation belt electron dynamics will be discussed in context of the June 1st, 2013 storm-time dropout event.

  17. Previous ISD Program Review.

    Science.gov (United States)

    1981-03-01

    report. The detail required for such a review would be unwieldy and would comsume inordinate amounts of time. The result of the document review will...attempts have been made at writing specific behavioral objectives (SBOs). These, however, have proven to be inadequate in that they are not stated in... behavioral terms (e.g., "will understand," "will have a knowledge of," etc.). C. Development of CRO/CRTs? In nearly all cases, ISD teams are just

  18. Meteorological Uncertainty of atmospheric Dispersion model results (MUD)

    DEFF Research Database (Denmark)

    Havskov Sørensen, Jens; Amstrup, Bjarne; Feddersen, Henrik

    The MUD project addresses assessment of uncertainties of atmospheric dispersion model predictions, as well as possibilities for optimum presentation to decision makers. Previously, it has not been possible to estimate such uncertainties quantitatively, but merely to calculate the ‘most likely’ di...

  19. The uncertainty analysis of model results a practical guide

    CERN Document Server

    Hofer, Eduard

    2018-01-01

    This book is a practical guide to the uncertainty analysis of computer model applications. Used in many areas, such as engineering, ecology and economics, computer models are subject to various uncertainties at the level of model formulations, parameter values and input data. Naturally, it would be advantageous to know the combined effect of these uncertainties on the model results as well as whether the state of knowledge should be improved in order to reduce the uncertainty of the results most effectively. The book supports decision-makers, model developers and users in their argumentation for an uncertainty analysis and assists them in the interpretation of the analysis results.

  20. V and V Efforts of Auroral Precipitation Models: Preliminary Results

    Science.gov (United States)

    Zheng, Yihua; Kuznetsova, Masha; Rastaetter, Lutz; Hesse, Michael

    2011-01-01

    Auroral precipitation models have been valuable both in terms of space weather applications and space science research. Yet very limited testing has been performed regarding model performance. A variety of auroral models are available, including empirical models that are parameterized by geomagnetic indices or upstream solar wind conditions, now casting models that are based on satellite observations, or those derived from physics-based, coupled global models. In this presentation, we will show our preliminary results regarding V&V efforts of some of the models.

  1. Verification of aseismic design model by using experimental results

    International Nuclear Information System (INIS)

    Mizuno, N.; Sugiyama, N.; Suzuki, T.; Shibata, Y.; Miura, K.; Miyagawa, N.

    1985-01-01

    A lattice model is applied as an analysis model for an aseismic design of the Hamaoka nuclear reactor building. With object to verify an availability of this design model, two reinforced concrete blocks are constructed on the ground and the forced vibration tests are carried out. The test results are well followed by simulation analysis using the lattice model. Damping value of the ground obtained from the test is more conservative than the design value. (orig.)

  2. Identifiability Results for Several Classes of Linear Compartment Models.

    Science.gov (United States)

    Meshkat, Nicolette; Sullivant, Seth; Eisenberg, Marisa

    2015-08-01

    Identifiability concerns finding which unknown parameters of a model can be estimated, uniquely or otherwise, from given input-output data. If some subset of the parameters of a model cannot be determined given input-output data, then we say the model is unidentifiable. In this work, we study linear compartment models, which are a class of biological models commonly used in pharmacokinetics, physiology, and ecology. In past work, we used commutative algebra and graph theory to identify a class of linear compartment models that we call identifiable cycle models, which are unidentifiable but have the simplest possible identifiable functions (so-called monomial cycles). Here we show how to modify identifiable cycle models by adding inputs, adding outputs, or removing leaks, in such a way that we obtain an identifiable model. We also prove a constructive result on how to combine identifiable models, each corresponding to strongly connected graphs, into a larger identifiable model. We apply these theoretical results to several real-world biological models from physiology, cell biology, and ecology.

  3. Results of the Marine Ice Sheet Model Intercomparison Project, MISMIP

    Directory of Open Access Journals (Sweden)

    F. Pattyn

    2012-05-01

    Full Text Available Predictions of marine ice-sheet behaviour require models that are able to robustly simulate grounding line migration. We present results of an intercomparison exercise for marine ice-sheet models. Verification is effected by comparison with approximate analytical solutions for flux across the grounding line using simplified geometrical configurations (no lateral variations, no effects of lateral buttressing. Unique steady state grounding line positions exist for ice sheets on a downward sloping bed, while hysteresis occurs across an overdeepened bed, and stable steady state grounding line positions only occur on the downward-sloping sections. Models based on the shallow ice approximation, which does not resolve extensional stresses, do not reproduce the approximate analytical results unless appropriate parameterizations for ice flux are imposed at the grounding line. For extensional-stress resolving "shelfy stream" models, differences between model results were mainly due to the choice of spatial discretization. Moving grid methods were found to be the most accurate at capturing grounding line evolution, since they track the grounding line explicitly. Adaptive mesh refinement can further improve accuracy, including fixed grid models that generally perform poorly at coarse resolution. Fixed grid models, with nested grid representations of the grounding line, are able to generate accurate steady state positions, but can be inaccurate over transients. Only one full-Stokes model was included in the intercomparison, and consequently the accuracy of shelfy stream models as approximations of full-Stokes models remains to be determined in detail, especially during transients.

  4. Generalised Chou-Yang model and recent results

    International Nuclear Information System (INIS)

    Fazal-e-Aleem; Rashid, H.

    1995-09-01

    It is shown that most recent results of E710 and UA4/2 collaboration for the total cross section and ρ together with earlier measurements give good agreement with measurements for the differential cross section at 546 and 1800 GeV the framework of Generalised Chou-Yang model. These results are also compared with the predictions of other models. (author). 16 refs, 2 figs

  5. Generalised Chou-Yang model and recent results

    Energy Technology Data Exchange (ETDEWEB)

    Fazal-e-Aleem [International Centre for Theoretical Physics, Trieste (Italy); Rashid, H. [Punjab Univ., Lahore (Pakistan). Centre for High Energy Physics

    1996-12-31

    It is shown that most recent results of E710 and UA4/2 collaboration for the total cross section and {rho} together with earlier measurements give good agreement with measurements for the differential cross section at 546 and 1800 GeV within the framework of Generalised Chou-Yang model. These results are also compared with the predictions of other models. (author) 16 refs.

  6. Generalised Chou-Yang model and recent results

    International Nuclear Information System (INIS)

    Fazal-e-Aleem; Rashid, H.

    1996-01-01

    It is shown that most recent results of E710 and UA4/2 collaboration for the total cross section and ρ together with earlier measurements give good agreement with measurements for the differential cross section at 546 and 1800 GeV within the framework of Generalised Chou-Yang model. These results are also compared with the predictions of other models. (author)

  7. Results from the IAEA benchmark of spallation models

    International Nuclear Information System (INIS)

    Leray, S.; David, J.C.; Khandaker, M.; Mank, G.; Mengoni, A.; Otsuka, N.; Filges, D.; Gallmeier, F.; Konobeyev, A.; Michel, R.

    2011-01-01

    Spallation reactions play an important role in a wide domain of applications. In the simulation codes used in this field, the nuclear interaction cross-sections and characteristics are computed by spallation models. The International Atomic Energy Agency (IAEA) has recently organised a benchmark of the spallation models used or that could be used in the future into high-energy transport codes. The objectives were, first, to assess the prediction capabilities of the different spallation models for the different mass and energy regions and the different exit channels and, second, to understand the reason for the success or deficiency of the models. Results of the benchmark concerning both the analysis of the prediction capabilities of the models and the first conclusions on the physics of spallation models are presented. (authors)

  8. The effect of bathymetric filtering on nearshore process model results

    Science.gov (United States)

    Plant, N.G.; Edwards, K.L.; Kaihatu, J.M.; Veeramony, J.; Hsu, L.; Holland, K.T.

    2009-01-01

    Nearshore wave and flow model results are shown to exhibit a strong sensitivity to the resolution of the input bathymetry. In this analysis, bathymetric resolution was varied by applying smoothing filters to high-resolution survey data to produce a number of bathymetric grid surfaces. We demonstrate that the sensitivity of model-predicted wave height and flow to variations in bathymetric resolution had different characteristics. Wave height predictions were most sensitive to resolution of cross-shore variability associated with the structure of nearshore sandbars. Flow predictions were most sensitive to the resolution of intermediate scale alongshore variability associated with the prominent sandbar rhythmicity. Flow sensitivity increased in cases where a sandbar was closer to shore and shallower. Perhaps the most surprising implication of these results is that the interpolation and smoothing of bathymetric data could be optimized differently for the wave and flow models. We show that errors between observed and modeled flow and wave heights are well predicted by comparing model simulation results using progressively filtered bathymetry to results from the highest resolution simulation. The damage done by over smoothing or inadequate sampling can therefore be estimated using model simulations. We conclude that the ability to quantify prediction errors will be useful for supporting future data assimilation efforts that require this information.

  9. More performance results and implementation of an object oriented track reconstruction model in different OO frameworks

    International Nuclear Information System (INIS)

    Gaines, Irwin; Qian Sijin

    2001-01-01

    This is an update of the report about an Object Oriented (OO) track reconstruction model, which was presented in the previous AIHENP'99 at Crete, Greece. The OO model for the Kalman filtering method has been designed for high energy physics experiments at high luminosity hadron colliders. It has been coded in the C++ programming language and successfully implemented into a few different OO computing environments of the CMS and ATLAS experiments at the future Large Hadron Collider at CERN. We shall report: (1) more performance result: (2) implementing the OO model into the new SW OO framework 'Athena' of ATLAS experiment and some upgrades of the OO model itself

  10. Cost-Effectiveness Model for Chemoimmunotherapy Options in Patients with Previously Untreated Chronic Lymphocytic Leukemia Unsuitable for Full-Dose Fludarabine-Based Therapy.

    Science.gov (United States)

    Becker, Ursula; Briggs, Andrew H; Moreno, Santiago G; Ray, Joshua A; Ngo, Phuong; Samanta, Kunal

    2016-06-01

    To evaluate the cost-effectiveness of treatment with anti-CD20 monoclonal antibody obinutuzumab plus chlorambucil (GClb) in untreated patients with chronic lymphocytic leukemia unsuitable for full-dose fludarabine-based therapy. A Markov model was used to assess the cost-effectiveness of GClb versus other chemoimmunotherapy options. The model comprised three mutually exclusive health states: "progression-free survival (with/without therapy)", "progression (refractory/relapsed lines)", and "death". Each state was assigned a health utility value representing patients' quality of life and a specific cost value. Comparisons between GClb and rituximab plus chlorambucil or only chlorambucil were performed using patient-level clinical trial data; other comparisons were performed via a network meta-analysis using information gathered in a systematic literature review. To support the model, a utility elicitation study was conducted from the perspective of the UK National Health Service. There was good agreement between the model-predicted progression-free and overall survival and that from the CLL11 trial. On incorporating data from the indirect treatment comparisons, it was found that GClb was cost-effective with a range of incremental cost-effectiveness ratios below a threshold of £30,000 per quality-adjusted life-year gained, and remained so during deterministic and probabilistic sensitivity analyses under various scenarios. GClb was estimated to increase both quality-adjusted life expectancy and treatment costs compared with several commonly used therapies, with incremental cost-effectiveness ratios below commonly referenced UK thresholds. This article offers a real example of how to combine direct and indirect evidence in a cost-effectiveness analysis of oncology drugs. Copyright © 2016 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  11. Circulation in the Gulf of Trieste: measurements and model results

    International Nuclear Information System (INIS)

    Bogunovici, B.; Malacic, V.

    2008-01-01

    The study presents seasonal variability of currents in the southern part of the Gulf of Trieste. A time series analysis of currents and wind stress for the period 2003-2006, which were measured by the coastal oceanographic buoy, was conducted. A comparison between these data and results obtained from a numerical model of circulation in the Gulf was performed to validate model results. Three different approaches were applied to the wind data to determine the wind stress. Similarities were found between Kondo and Smith approaches while the method of Vera shows differences which were particularly noticeable for lower (= 1 m/s) and higher wind speeds (= 15 m/s). Mean currents in the surface layer are generally outflow currents from the Gulf due to wind forcing (bora). However in all other depth layers inflow currents are dominant. With the principal component analysis (Pca) major and minor axes were determined for all seasons. The major axis of maximum variance in years between 2003 and 2006 is prevailing in Ne-Sw direction, which is parallel to the coastline. Comparison of observation and model results is showing that currents are similar (in direction) for the surface and bottom layers but are significantly different for the middle layer (5-13 m). At a depth between 14-21 m velocities are comparable in direction as well as in magnitude even though model values are higher. Higher values of modelled currents at the surface and near the bottom are explained by higher values of wind stress that were used in the model as driving input with respect to the stress calculated from the measured winds. Larger values of modelled currents near the bottom are related to the larger inflow that needs to compensate for the larger modelled outflow at the surface. However, inspection of the vertical structure of temperature, salinity and density shows that the model is reproducing a weaker density gradient which enables the penetration of the outflow surface currents to larger depths.

  12. Melt coolability modeling and comparison to MACE test results

    International Nuclear Information System (INIS)

    Farmer, M.T.; Sienicki, J.J.; Spencer, B.W.

    1992-01-01

    An important question in the assessment of severe accidents in light water nuclear reactors is the ability of water to quench a molten corium-concrete interaction and thereby terminate the accident progression. As part of the Melt Attack and Coolability Experiment (MACE) Program, phenomenological models of the corium quenching process are under development. The modeling approach considers both bulk cooldown and crust-limited heat transfer regimes, as well as criteria for the pool thermal hydraulic conditions which separate the two regimes. The model is then compared with results of the MACE experiments

  13. Global history of the ancient monocot family Araceae inferred with models accounting for past continental positions and previous ranges based on fossils.

    Science.gov (United States)

    Nauheimer, Lars; Metzler, Dirk; Renner, Susanne S

    2012-09-01

    The family Araceae (3790 species, 117 genera) has one of the oldest fossil records among angiosperms. Ecologically, members of this family range from free-floating aquatics (Pistia and Lemna) to tropical epiphytes. Here, we infer some of the macroevolutionary processes that have led to the worldwide range of this family and test how the inclusion of fossil (formerly occupied) geographical ranges affects biogeographical reconstructions. Using a complete genus-level phylogeny from plastid sequences and outgroups representing the 13 other Alismatales families, we estimate divergence times by applying different clock models and reconstruct range shifts under different models of past continental connectivity, with or without the incorporation of fossil locations. Araceae began to diversify in the Early Cretaceous (when the breakup of Pangea was in its final stages), and all eight subfamilies existed before the K/T boundary. Early lineages persist in Laurasia, with several relatively recent entries into Africa, South America, South-East Asia and Australia. Water-associated habitats appear to be ancestral in the family, and DNA substitution rates are especially high in free-floating Araceae. Past distributions inferred when fossils are included differ in nontrivial ways from those without fossils. Our complete genus-level time-scale for the Araceae may prove to be useful for ecological and physiological studies. © 2012 The Authors. New Phytologist © 2012 New Phytologist Trust.

  14. Higher plant modelling for life support applications: first results of a simple mechanistic model

    Science.gov (United States)

    Hezard, Pauline; Dussap, Claude-Gilles; Sasidharan L, Swathy

    2012-07-01

    In the case of closed ecological life support systems, the air and water regeneration and food production are performed using microorganisms and higher plants. Wheat, rice, soybean, lettuce, tomato or other types of eatable annual plants produce fresh food while recycling CO2 into breathable oxygen. Additionally, they evaporate a large quantity of water, which can be condensed and used as potable water. This shows that recycling functions of air revitalization and food production are completely linked. Consequently, the control of a growth chamber for higher plant production has to be performed with efficient mechanistic models, in order to ensure a realistic prediction of plant behaviour, water and gas recycling whatever the environmental conditions. Purely mechanistic models of plant production in controlled environments are not available yet. This is the reason why new models must be developed and validated. This work concerns the design and test of a simplified version of a mathematical model coupling plant architecture and mass balance purposes in order to compare its results with available data of lettuce grown in closed and controlled chambers. The carbon exchange rate, water absorption and evaporation rate, biomass fresh weight as well as leaf surface are modelled and compared with available data. The model consists of four modules. The first one evaluates plant architecture, like total leaf surface, leaf area index and stem length data. The second one calculates the rate of matter and energy exchange depending on architectural and environmental data: light absorption in the canopy, CO2 uptake or release, water uptake and evapotranspiration. The third module evaluates which of the previous rates is limiting overall biomass growth; and the last one calculates biomass growth rate depending on matter exchange rates, using a global stoichiometric equation. All these rates are a set of differential equations, which are integrated with time in order to provide

  15. Relationship Marketing results: proposition of a cognitive mapping model

    Directory of Open Access Journals (Sweden)

    Iná Futino Barreto

    2015-12-01

    Full Text Available Objective - This research sought to develop a cognitive model that expresses how marketing professionals understand the relationship between the constructs that define relationship marketing (RM. It also tried to understand, using the obtained model, how objectives in this field are achieved. Design/methodology/approach – Through cognitive mapping, we traced 35 individual mental maps, highlighting how each respondent understands the interactions between RM elements. Based on the views of these individuals, we established an aggregate mental map. Theoretical foundation – The topic is based on a literature review that explores the RM concept and its main elements. Based on this review, we listed eleven main constructs. Findings – We established an aggregate mental map that represents the RM structural model. Model analysis identified that CLV is understood as the final result of RM. We also observed that the impact of most of the RM elements on CLV is brokered by loyalty. Personalization and quality, on the other hand, proved to be process input elements, and are the ones that most strongly impact others. Finally, we highlight that elements that punish customers are much less effective than elements that benefit them. Contributions - The model was able to insert core elements of RM, but absent from most formal models: CLV and customization. The analysis allowed us to understand the interactions between the RM elements and how the end result of RM (CLV is formed. This understanding improves knowledge on the subject and helps guide, assess and correct actions.

  16. Functional results-oriented healthcare leadership: a novel leadership model.

    Science.gov (United States)

    Al-Touby, Salem Said

    2012-03-01

    This article modifies the traditional functional leadership model to accommodate contemporary needs in healthcare leadership based on two findings. First, the article argues that it is important that the ideal healthcare leadership emphasizes the outcomes of the patient care more than processes and structures used to deliver such care; and secondly, that the leadership must strive to attain effectiveness of their care provision and not merely targeting the attractive option of efficient operations. Based on these premises, the paper reviews the traditional Functional Leadership Model and the three elements that define the type of leadership an organization has namely, the tasks, the individuals, and the team. The article argues that concentrating on any one of these elements is not ideal and proposes adding a new element to the model to construct a novel Functional Result-Oriented healthcare leadership model. The recommended Functional-Results Oriented leadership model embosses the results element on top of the other three elements so that every effort on healthcare leadership is directed towards attaining excellent patient outcomes.

  17. Previously unknown species of Aspergillus.

    Science.gov (United States)

    Gautier, M; Normand, A-C; Ranque, S

    2016-08-01

    The use of multi-locus DNA sequence analysis has led to the description of previously unknown 'cryptic' Aspergillus species, whereas classical morphology-based identification of Aspergillus remains limited to the section or species-complex level. The current literature highlights two main features concerning these 'cryptic' Aspergillus species. First, the prevalence of such species in clinical samples is relatively high compared with emergent filamentous fungal taxa such as Mucorales, Scedosporium or Fusarium. Second, it is clearly important to identify these species in the clinical laboratory because of the high frequency of antifungal drug-resistant isolates of such Aspergillus species. Matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) has recently been shown to enable the identification of filamentous fungi with an accuracy similar to that of DNA sequence-based methods. As MALDI-TOF MS is well suited to the routine clinical laboratory workflow, it facilitates the identification of these 'cryptic' Aspergillus species at the routine mycology bench. The rapid establishment of enhanced filamentous fungi identification facilities will lead to a better understanding of the epidemiology and clinical importance of these emerging Aspergillus species. Based on routine MALDI-TOF MS-based identification results, we provide original insights into the key interpretation issues of a positive Aspergillus culture from a clinical sample. Which ubiquitous species that are frequently isolated from air samples are rarely involved in human invasive disease? Can both the species and the type of biological sample indicate Aspergillus carriage, colonization or infection in a patient? Highly accurate routine filamentous fungi identification is central to enhance the understanding of these previously unknown Aspergillus species, with a vital impact on further improved patient care. Copyright © 2016 European Society of Clinical Microbiology and

  18. Value of the distant future: Model-independent results

    Science.gov (United States)

    Katz, Yuri A.

    2017-01-01

    This paper shows that the model-independent account of correlations in an interest rate process or a log-consumption growth process leads to declining long-term tails of discount curves. Under the assumption of an exponentially decaying memory in fluctuations of risk-free real interest rates, I derive the analytical expression for an apt value of the long run discount factor and provide a detailed comparison of the obtained result with the outcome of the benchmark risk-free interest rate models. Utilizing the standard consumption-based model with an isoelastic power utility of the representative economic agent, I derive the non-Markovian generalization of the Ramsey discounting formula. Obtained analytical results allowing simple calibration, may augment the rigorous cost-benefit and regulatory impact analysis of long-term environmental and infrastructure projects.

  19. Storm-time ring current: model-dependent results

    Directory of Open Access Journals (Sweden)

    N. Yu. Ganushkina

    2012-01-01

    Full Text Available The main point of the paper is to investigate how much the modeled ring current depends on the representations of magnetic and electric fields and boundary conditions used in simulations. Two storm events, one moderate (SymH minimum of −120 nT on 6–7 November 1997 and one intense (SymH minimum of −230 nT on 21–22 October 1999, are modeled. A rather simple ring current model is employed, namely, the Inner Magnetosphere Particle Transport and Acceleration model (IMPTAM, in order to make the results most evident. Four different magnetic field and two electric field representations and four boundary conditions are used. We find that different combinations of the magnetic and electric field configurations and boundary conditions result in very different modeled ring current, and, therefore, the physical conclusions based on simulation results can differ significantly. A time-dependent boundary outside of 6.6 RE gives a possibility to take into account the particles in the transition region (between dipole and stretched field lines forming partial ring current and near-Earth tail current in that region. Calculating the model SymH* by Biot-Savart's law instead of the widely used Dessler-Parker-Sckopke (DPS relation gives larger and more realistic values, since the currents are calculated in the regions with nondipolar magnetic field. Therefore, the boundary location and the method of SymH* calculation are of key importance for ring current data-model comparisons to be correctly interpreted.

  20. Test results of the SMES model coil. Pulse performance

    International Nuclear Information System (INIS)

    Hamajima, Takataro; Shimada, Mamoru; Ono, Michitaka

    1998-01-01

    A model coil for superconducting magnetic energy storage (SMES model coil) has been developed to establish the component technologies needed for a small-scale 100 kWh SMES device. The SMES model coil was fabricated, and then performance tests were carried out in 1996. The coil was successfully charged up to around 30 kA and down to zero at the same ramp rate of magnetic field experienced in a 100 kWh SMES device. AC loss in the coil was measured by an enthalpy method as parameters of ramp rate and flat top current. The results were evaluated by an analysis and compared with short-sample test results. The measured hysteresis loss is in good agreement with that estimated from the short-sample results. It was found that the coupling loss of the coil consists of two major coupling time constants. One is a short time constant of about 200 ms, which is in agreement with the test results of a short real conductor. The other is a long time constant of about 30 s, which could not be expected from the short sample test results. (author)

  1. Modeling Results For the ITER Cryogenic Fore Pump. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Pfotenhauer, John M. [University of Wisconsin, Madison, WI (United States); Zhang, Dongsheng [University of Wisconsin, Madison, WI (United States)

    2014-03-31

    A numerical model characterizing the operation of a cryogenic fore-pump (CFP) for ITER has been developed at the University of Wisconsin – Madison during the period from March 15, 2011 through June 30, 2014. The purpose of the ITER-CFP is to separate hydrogen isotopes from helium gas, both making up the exhaust components from the ITER reactor. The model explicitly determines the amount of hydrogen that is captured by the supercritical-helium-cooled pump as a function of the inlet temperature of the supercritical helium, its flow rate, and the inlet conditions of the hydrogen gas flow. Furthermore the model computes the location and amount of hydrogen captured in the pump as a function of time. Throughout the model’s development, and as a calibration check for its results, it has been extensively compared with the measurements of a CFP prototype tested at Oak Ridge National Lab. The results of the model demonstrate that the quantity of captured hydrogen is very sensitive to the inlet temperature of the helium coolant on the outside of the cryopump. Furthermore, the model can be utilized to refine those tests, and suggests methods that could be incorporated in the testing to enhance the usefulness of the measured data.

  2. Methodology and Results of Mathematical Modelling of Complex Technological Processes

    Science.gov (United States)

    Mokrova, Nataliya V.

    2018-03-01

    The methodology of system analysis allows us to draw a mathematical model of the complex technological process. The mathematical description of the plasma-chemical process was proposed. The importance the quenching rate and initial temperature decrease time was confirmed for producing the maximum amount of the target product. The results of numerical integration of the system of differential equations can be used to describe reagent concentrations, plasma jet rate and temperature in order to achieve optimal mode of hardening. Such models are applicable both for solving control problems and predicting future states of sophisticated technological systems.

  3. Modeling vertical loads in pools resulting from fluid injection

    International Nuclear Information System (INIS)

    Lai, W.; McCauley, E.W.

    1978-01-01

    Table-top model experiments were performed to investigate pressure suppression pool dynamics effects due to a postulated loss-of-coolant accident (LOCA) for the Peachbottom Mark I boiling water reactor containment system. The results guided subsequent conduct of experiments in the 1 / 5 -scale facility and provided new insight into the vertical load function (VLF). Model experiments show an oscillatory VLF with the download typically double-spiked followed by a more gradual sinusoidal upload. The load function contains a high frequency oscillation superimposed on a low frequency one; evidence from measurements indicates that the oscillations are initiated by fluid dynamics phenomena

  4. Results of the eruptive column model inter-comparison study

    Science.gov (United States)

    Costa, Antonio; Suzuki, Yujiro; Cerminara, M.; Devenish, Ben J.; Esposti Ongaro, T.; Herzog, Michael; Van Eaton, Alexa; Denby, L.C.; Bursik, Marcus; de' Michieli Vitturi, Mattia; Engwell, S.; Neri, Augusto; Barsotti, Sara; Folch, Arnau; Macedonio, Giovanni; Girault, F.; Carazzo, G.; Tait, S.; Kaminski, E.; Mastin, Larry G.; Woodhouse, Mark J.; Phillips, Jeremy C.; Hogg, Andrew J.; Degruyter, Wim; Bonadonna, Costanza

    2016-01-01

    This study compares and evaluates one-dimensional (1D) and three-dimensional (3D) numerical models of volcanic eruption columns in a set of different inter-comparison exercises. The exercises were designed as a blind test in which a set of common input parameters was given for two reference eruptions, representing a strong and a weak eruption column under different meteorological conditions. Comparing the results of the different models allows us to evaluate their capabilities and target areas for future improvement. Despite their different formulations, the 1D and 3D models provide reasonably consistent predictions of some of the key global descriptors of the volcanic plumes. Variability in plume height, estimated from the standard deviation of model predictions, is within ~ 20% for the weak plume and ~ 10% for the strong plume. Predictions of neutral buoyancy level are also in reasonably good agreement among the different models, with a standard deviation ranging from 9 to 19% (the latter for the weak plume in a windy atmosphere). Overall, these discrepancies are in the range of observational uncertainty of column height. However, there are important differences amongst models in terms of local properties along the plume axis, particularly for the strong plume. Our analysis suggests that the simplified treatment of entrainment in 1D models is adequate to resolve the general behaviour of the weak plume. However, it is inadequate to capture complex features of the strong plume, such as large vortices, partial column collapse, or gravitational fountaining that strongly enhance entrainment in the lower atmosphere. We conclude that there is a need to more accurately quantify entrainment rates, improve the representation of plume radius, and incorporate the effects of column instability in future versions of 1D volcanic plume models.

  5. Initial CGE Model Results Summary Exogenous and Endogenous Variables Tests

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, Brian Keith [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Boero, Riccardo [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Rivera, Michael Kelly [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-08-07

    The following discussion presents initial results of tests of the most recent version of the National Infrastructure Simulation and Analysis Center Dynamic Computable General Equilibrium (CGE) model developed by Los Alamos National Laboratory (LANL). The intent of this is to test and assess the model’s behavioral properties. The test evaluated whether the predicted impacts are reasonable from a qualitative perspective. This issue is whether the predicted change, be it an increase or decrease in other model variables, is consistent with prior economic intuition and expectations about the predicted change. One of the purposes of this effort is to determine whether model changes are needed in order to improve its behavior qualitatively and quantitatively.

  6. Theoretical results on the tandem junction solar cell based on its Ebers-Moll transistor model

    Science.gov (United States)

    Goradia, C.; Vaughn, J.; Baraona, C. R.

    1980-01-01

    A one-dimensional theoretical model of the tandem junction solar cell (TJC) with base resistivity greater than about 1 ohm-cm and under low level injection has been derived. This model extends a previously published conceptual model which treats the TJC as an npn transistor. The model gives theoretical expressions for each of the Ebers-Moll type currents of the illuminated TJC and allows for the calculation of the spectral response, I(sc), V(oc), FF and eta under variation of one or more of the geometrical and material parameters and 1MeV electron fluence. Results of computer calculations based on this model are presented and discussed. These results indicate that for space applications, both a high beginning of life efficiency, greater than 15% AM0, and a high radiation tolerance can be achieved only with thin (less than 50 microns) TJC's with high base resistivity (greater than 10 ohm-cm).

  7. Lattice Hamiltonian approach to the Schwinger model. Further results from the strong coupling expansion

    International Nuclear Information System (INIS)

    Szyniszewski, Marcin; Manchester Univ.; Cichy, Krzysztof; Poznan Univ.; Kujawa-Cichy, Agnieszka

    2014-10-01

    We employ exact diagonalization with strong coupling expansion to the massless and massive Schwinger model. New results are presented for the ground state energy and scalar mass gap in the massless model, which improve the precision to nearly 10 -9 %. We also investigate the chiral condensate and compare our calculations to previous results available in the literature. Oscillations of the chiral condensate which are present while increasing the expansion order are also studied and are shown to be directly linked to the presence of flux loops in the system.

  8. First experiments results about the engineering model of Rapsodie

    International Nuclear Information System (INIS)

    Chalot, A.; Ginier, R.; Sauvage, M.

    1964-01-01

    This report deals with the first series of experiments carried out on the engineering model of Rapsodie and on an associated sodium facility set in a laboratory hall of Cadarache. It conveys more precisely: 1/ - The difficulties encountered during the erection and assembly of the engineering model and a compilation of the results of the first series of experiments and tests carried out on this installation (loading of the subassemblies preheating, thermal chocks...). 2/ - The experiments and tests carried out on the two prototypes control rod drive mechanisms which brought to the choice for the design of the definitive drive mechanism. As a whole, the results proved the validity of the general design principles adopted for Rapsodie. (authors) [fr

  9. Acoustic results of the Boeing model 360 whirl tower test

    Science.gov (United States)

    Watts, Michael E.; Jordan, David

    1990-09-01

    An evaluation is presented for whirl tower test results of the Model 360 helicopter's advanced, high-performance four-bladed composite rotor system intended to facilitate over-200-knot flight. During these performance measurements, acoustic data were acquired by seven microphones. A comparison of whirl-tower tests with theory indicate that theoretical prediction accuracies vary with both microphone position and the inclusion of ground reflection. Prediction errors varied from 0 to 40 percent of the measured signal-to-peak amplitude.

  10. Exact results for the one dimensional asymmetric exclusion model

    International Nuclear Information System (INIS)

    Derrida, B.; Evans, M.R.; Pasquier, V.

    1993-01-01

    The asymmetric exclusion model describes a system of particles hopping in a preferred direction with hard core repulsion. These particles can be thought of as charged particles in a field, as steps of an interface, as cars in a queue. Several exact results concerning the steady state of this system have been obtained recently. The solution consists of representing the weights of the configurations in the steady state as products of non-commuting matrices. (author)

  11. Review of Current Standard Model Results in ATLAS

    CERN Document Server

    Brandt, Gerhard; The ATLAS collaboration

    2018-01-01

    This talk highlights results selected from the Standard Model research programme of the ATLAS Collaboration at the Large Hadron Collider. Results using data from $p-p$ collisions at $\\sqrt{s}=7,8$~TeV in LHC Run-1 as well as results using data at $\\sqrt{s}=13$~TeV in LHC Run-2 are covered. The status of cross section measurements from soft QCD processes and jet production as well as photon production are presented. The presentation extends to vector boson production with associated jets. Precision measurements of the production of $W$ and $Z$ bosons, including a first measurement of the mass of the $W$ bosons, $m_W$, are discussed. The programme to measure electroweak processes with di-boson and tri-boson final states is outlined. All presented measurements are compatible with Standard Model descriptions and allow to further constrain it. In addition they allow to probe new physics which would manifest through extra gauge couplings, or Standard Model gauge couplings deviating from their predicted value.

  12. Comparison of transient PCRV model test results with analysis

    International Nuclear Information System (INIS)

    Marchertas, A.H.; Belytschko, T.B.

    1979-01-01

    Comparisons are made of transient data derived from simple models of a reactor containment vessel with analytical solutions. This effort is a part of the ongoing process of development and testing of the DYNAPCON computer code. The test results used in these comparisons were obtained from scaled models of the British sodium cooled fast breeder program. The test structure is a scaled model of a cylindrically shaped reactor containment vessel made of concrete. This concrete vessel is prestressed axially by holddown bolts spanning the top and bottom slabs along the cylindrical walls, and is also prestressed circumferentially by a number of cables wrapped around the vessel. For test purposes this containment vessel is partially filled with water, which comes in direct contact with the vessel walls. The explosive charge is immersed in the pool of water and is centrally suspended from the top of the vessel. The load history was obtained from an ICECO analysis, using the equations of state for the source and the water. A detailed check of this solution was made to assure that the derived loading did provide the correct input. The DYNAPCON code was then used for the analysis of the prestressed concrete containment model. This analysis required the simulation of prestressing and the response of the model to the applied transient load. The calculations correctly predict the magnitudes of displacements of the PCRV model. In addition, the displacement time histories obtained from the calculations reproduce the general features of the experimental records: the period elongation and amplitude increase as compared to an elastic solution, and also the absence of permanent displacement. However, the period still underestimates the experiment, while the amplitude is generally somewhat large

  13. Thermal-Chemical Model Of Subduction: Results And Tests

    Science.gov (United States)

    Gorczyk, W.; Gerya, T. V.; Connolly, J. A.; Yuen, D. A.; Rudolph, M.

    2005-12-01

    Seismic structures with strong positive and negative velocity anomalies in the mantle wedge above subduction zones have been interpreted as thermally and/or chemically induced phenomena. We have developed a thermal-chemical model of subduction, which constrains the dynamics of seismic velocity structure beneath volcanic arcs. Our simulations have been calculated over a finite-difference grid with (201×101) to (201×401) regularly spaced Eulerian points, using 0.5 million to 10 billion markers. The model couples numerical thermo-mechanical solution with Gibbs energy minimization to investigate the dynamic behavior of partially molten upwellings from slabs (cold plumes) and structures associated with their development. The model demonstrates two chemically distinct types of plumes (mixed and unmixed), and various rigid body rotation phenomena in the wedge (subduction wheel, fore-arc spin, wedge pin-ball). These thermal-chemical features strongly perturb seismic structure. Their occurrence is dependent on the age of subducting slab and the rate of subduction.The model has been validated through a series of test cases and its results are consistent with a variety of geological and geophysical data. In contrast to models that attribute a purely thermal origin for mantle wedge seismic anomalies, the thermal-chemical model is able to simulate the strong variations of seismic velocity existing beneath volcanic arcs which are associated with development of cold plumes. In particular, molten regions that form beneath volcanic arcs as a consequence of vigorous cold wet plumes are manifest by > 20% variations in the local Poisson ratio, as compared to variations of ~ 2% expected as a consequence of temperature variation within the mantle wedge.

  14. Measurement model choice influenced randomized controlled trial results.

    Science.gov (United States)

    Gorter, Rosalie; Fox, Jean-Paul; Apeldoorn, Adri; Twisk, Jos

    2016-11-01

    In randomized controlled trials (RCTs), outcome variables are often patient-reported outcomes measured with questionnaires. Ideally, all available item information is used for score construction, which requires an item response theory (IRT) measurement model. However, in practice, the classical test theory measurement model (sum scores) is mostly used, and differences between response patterns leading to the same sum score are ignored. The enhanced differentiation between scores with IRT enables more precise estimation of individual trajectories over time and group effects. The objective of this study was to show the advantages of using IRT scores instead of sum scores when analyzing RCTs. Two studies are presented, a real-life RCT, and a simulation study. Both IRT and sum scores are used to measure the construct and are subsequently used as outcomes for effect calculation. The bias in RCT results is conditional on the measurement model that was used to construct the scores. A bias in estimated trend of around one standard deviation was found when sum scores were used, where IRT showed negligible bias. Accurate statistical inferences are made from an RCT study when using IRT to estimate construct measurements. The use of sum scores leads to incorrect RCT results. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. Conceptual aspects: analyses law, ethical, human, technical, social factors of development ICT, e-learning and intercultural development in different countries setting out the previous new theoretical model and preliminary findings

    NARCIS (Netherlands)

    Kommers, Petrus A.M.; Smyrnova-Trybulska, Eugenia; Morze, Natalia; Issa, Tomayess; Issa, Theodora

    2015-01-01

    This paper, prepared by an international team of authors focuses on the conceptual aspects: analyses law, ethical, human, technical, social factors of ICT development, e-learning and intercultural development in different countries, setting out the previous and new theoretical model and preliminary

  16. SR-Site groundwater flow modelling methodology, setup and results

    International Nuclear Information System (INIS)

    Selroos, Jan-Olof; Follin, Sven

    2010-12-01

    As a part of the license application for a final repository for spent nuclear fuel at Forsmark, the Swedish Nuclear Fuel and Waste Management Company (SKB) has undertaken three groundwater flow modelling studies. These are performed within the SR-Site project and represent time periods with different climate conditions. The simulations carried out contribute to the overall evaluation of the repository design and long-term radiological safety. Three time periods are addressed; the Excavation and operational phases, the Initial period of temperate climate after closure, and the Remaining part of the reference glacial cycle. The present report is a synthesis of the background reports describing the modelling methodology, setup, and results. It is the primary reference for the conclusions drawn in a SR-Site specific context concerning groundwater flow during the three climate periods. These conclusions are not necessarily provided explicitly in the background reports, but are based on the results provided in these reports. The main results and comparisons presented in the present report are summarised in the SR-Site Main report

  17. Geochemical controls on shale groundwaters: Results of reaction path modeling

    International Nuclear Information System (INIS)

    Von Damm, K.L.; VandenBrook, A.J.

    1989-03-01

    The EQ3NR/EQ6 geochemical modeling code was used to simulate the reaction of several shale mineralogies with different groundwater compositions in order to elucidate changes that may occur in both the groundwater compositions, and rock mineralogies and compositions under conditions which may be encountered in a high-level radioactive waste repository. Shales with primarily illitic or smectitic compositions were the focus of this study. The reactions were run at the ambient temperatures of the groundwaters and to temperatures as high as 250/degree/C, the approximate temperature maximum expected in a repository. All modeling assumed that equilibrium was achieved and treated the rock and water assemblage as a closed system. Graphite was used as a proxy mineral for organic matter in the shales. The results show that the presence of even a very small amount of reducing mineral has a large influence on the redox state of the groundwaters, and that either pyrite or graphite provides essentially the same results, with slight differences in dissolved C, Fe and S concentrations. The thermodynamic data base is inadequate at the present time to fully evaluate the speciation of dissolved carbon, due to the paucity of thermodynamic data for organic compounds. In the illitic cases the groundwaters resulting from interaction at elevated temperatures are acid, while the smectitic cases remain alkaline, although the final equilibrium mineral assemblages are quite similar. 10 refs., 8 figs., 15 tabs

  18. Loss of spent fuel pool cooling PRA: Model and results

    International Nuclear Information System (INIS)

    Siu, N.; Khericha, S.; Conroy, S.; Beck, S.; Blackman, H.

    1996-09-01

    This letter report documents models for quantifying the likelihood of loss of spent fuel pool cooling; models for identifying post-boiling scenarios that lead to core damage; qualitative and quantitative results generated for a selected plant that account for plant design and operational practices; a comparison of these results and those generated from earlier studies; and a review of available data on spent fuel pool accidents. The results of this study show that for a representative two-unit boiling water reactor, the annual probability of spent fuel pool boiling is 5 x 10 -5 and the annual probability of flooding associated with loss of spent fuel pool cooling scenarios is 1 x 10 -3 . Qualitative arguments are provided to show that the likelihood of core damage due to spent fuel pool boiling accidents is low for most US commercial nuclear power plants. It is also shown that, depending on the design characteristics of a given plant, the likelihood of either: (a) core damage due to spent fuel pool-associated flooding, or (b) spent fuel damage due to pool dryout, may not be negligible

  19. SR-Site groundwater flow modelling methodology, setup and results

    Energy Technology Data Exchange (ETDEWEB)

    Selroos, Jan-Olof (Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden)); Follin, Sven (SF GeoLogic AB, Taeby (Sweden))

    2010-12-15

    As a part of the license application for a final repository for spent nuclear fuel at Forsmark, the Swedish Nuclear Fuel and Waste Management Company (SKB) has undertaken three groundwater flow modelling studies. These are performed within the SR-Site project and represent time periods with different climate conditions. The simulations carried out contribute to the overall evaluation of the repository design and long-term radiological safety. Three time periods are addressed; the Excavation and operational phases, the Initial period of temperate climate after closure, and the Remaining part of the reference glacial cycle. The present report is a synthesis of the background reports describing the modelling methodology, setup, and results. It is the primary reference for the conclusions drawn in a SR-Site specific context concerning groundwater flow during the three climate periods. These conclusions are not necessarily provided explicitly in the background reports, but are based on the results provided in these reports. The main results and comparisons presented in the present report are summarised in the SR-Site Main report.

  20. Probabilistic Modeling of Updating Epistemic Uncertainty In Pile Capacity Prediction With a Single Failure Test Result

    Directory of Open Access Journals (Sweden)

    Indra Djati Sidi

    2017-12-01

    Full Text Available The model error N has been introduced to denote the discrepancy between measured and predicted capacity of pile foundation. This model error is recognized as epistemic uncertainty in pile capacity prediction. The statistics of N have been evaluated based on data gathered from various sites and may be considered only as a eneral-error trend in capacity prediction, providing crude estimates of the model error in the absence of more specific data from the site. The results of even a single load test to failure, should provide direct evidence of the pile capacity at a given site. Bayes theorem has been used as a rational basis for combining new data with previous data to revise assessment of uncertainty and reliability. This study is devoted to the development of procedures for updating model error (N, and subsequently the predicted pile capacity with a results of single failure test.

  1. Results of the benchmark for blade structural models, part A

    DEFF Research Database (Denmark)

    Lekou, D.J.; Chortis, D.; Belen Fariñas, A.

    2013-01-01

    A benchmark on structural design methods for blades was performed within the InnWind.Eu project under WP2 “Lightweight Rotor” Task 2.2 “Lightweight structural design”. The present document is describes the results of the comparison simulation runs that were performed by the partners involved within...... Task 2.2 of the InnWind.Eu project. The benchmark is based on the reference wind turbine and the reference blade provided by DTU [1]. "Structural Concept developers/modelers" of WP2 were provided with the necessary input for a comparison numerical simulation run, upon definition of the reference blade...

  2. Preliminary results of steel containment vessel model test

    International Nuclear Information System (INIS)

    Matsumoto, T.; Komine, K.; Arai, S.

    1997-01-01

    A high pressure test of a mixed-scaled model (1:10 in geometry and 1:4 in shell thickness) of a steel containment vessel (SCV), representing an improved boiling water reactor (BWR) Mark II containment, was conducted on December 11-12, 1996 at Sandia National Laboratories. This paper describes the preliminary results of the high pressure test. In addition, the preliminary post-test measurement data and the preliminary comparison of test data with pretest analysis predictions are also presented

  3. Results of the ITER toroidal field model coil project

    International Nuclear Information System (INIS)

    Salpietro, E.; Maix, R.

    2001-01-01

    In the scope of the ITER EDA one of the seven largest projects was devoted to the development, manufacture and testing of a Toroidal Field Model Coil (TFMC). The industry consortium AGAN manufactured the TFMC based on on a conceptual design developed by the ITER EDA EU Home Team. The TFMC was completed and assembled in the test facility TOSKA of the Forschungszentrum Karlsruhe in the first half of 2001. The first testing phase started in June 2001 and lasted till October 2001. The first results have shown that the main goals of the project have been achieved

  4. Dermal uptake of phthalates from clothing: comparison of model to human participant results

    DEFF Research Database (Denmark)

    Morrison, Glenn; Weschler, Charles J.; Bekö, Gabriel

    2016-01-01

    In this research, we extend a model of transdermal uptake of phthalates to include a layer of clothing. When compared with experimental results, this model better estimates dermal uptake of diethylphthalate (DEP) and di-n-butylphthalate (DnBP) than a previous model. It also demonstrates that uptake...... is sensitive to both the gap between skin and clothing and the time clothing is allowed to adsorb phthalates. The model predictions are consistent with the observation that exposed clothing increases dermal uptake when compared with uptake observed in bare-skin participants. Extension of this model beyond...... the cotton-phthalate system will be challenging until data on partition coefficients are quantified for other combinations of SVOCs, fabric materials and environmental conditions....

  5. Comparison of transient PCRV model test results with analysis

    International Nuclear Information System (INIS)

    Marchertas, A.H.; Belytschko, T.B.

    1979-01-01

    Comparisons are made of transient data derived from simple models of a reactor containment vessel with analytical solutions. This effort is a part of the ongoing process of development and testing of the DYNAPCON computer code. The test results used in these comparisons were obtained from scaled models of the British sodium cooled fast breeder program. The test structure is a scaled model of a cylindrically shaped reactor containment vessel made of concrete. This concrete vessel is prestressed axially by holddown bolts spanning the top and bottom slabs along the cylindrical walls, and is also prestressed circumferentially by a number of cables wrapped around the vessel. For test purposes this containment vessel is partially filled with water, which comes in direct contact with the vessel walls. The explosive charge is immersed in the pool of water and is centrally suspended from the top of the vessel. The tests are very similar to the series of tests made for the COVA experimental program, but the vessel here is the prestressed concrete container. (orig.)

  6. The similia principle: results obtained in a cellular model system.

    Science.gov (United States)

    Wiegant, Fred; Van Wijk, Roeland

    2010-01-01

    This paper describes the results of a research program focused on the beneficial effect of low dose stress conditions that were applied according to the similia principle to cells previously disturbed by more severe stress conditions. In first instance, we discuss criteria for research on the similia principle at the cellular level. Then, the homologous ('isopathic') approach is reviewed, in which the initial (high dose) stress used to disturb cellular physiology and the subsequent (low dose) stress are identical. Beneficial effects of low dose stress are described in terms of increased cellular survival capacity and at the molecular level as an increase in the synthesis of heat shock proteins (hsps). Both phenomena reflect a stimulation of the endogenous cellular self-recovery capacity. Low dose stress conditions applied in a homologous approach stimulate the synthesis of hsps and enhance survival in comparison with stressed cells that were incubated in the absence of low dose stress conditions. Thirdly, the specificity of the low dose stress condition is described where the initial (high dose) stress is different in nature from the subsequently applied (low dose) stress; the heterologous or 'heteropathic' approach. The results support the similia principle at the cellular level and add to understanding of how low dose stress conditions influence the regulatory processes underlying self-recovery. In addition, the phenomenon of 'symptom aggravation' which is also observed at the cellular level, is discussed in the context of self-recovery. Finally, the difference in efficiency between the homologous and the heterologous approach is discussed; a perspective is indicated for further research; and the relationship between studies on the similia principle and the recently introduced concept of 'postconditioning hormesis' is emphasized. Copyright 2009 The Faculty of Homeopathy. Published by Elsevier Ltd. All rights reserved.

  7. Comparison of analytical models and experimental results for single-event upset in CMOS SRAMs

    International Nuclear Information System (INIS)

    Mnich, T.M.; Diehl, S.E.; Shafer, B.D.

    1983-01-01

    In an effort to design fully radiation-hardened memories for satellite and deep-space applications, a 16K and a 2K CMOS static RAM were modeled for single-particle upset during the design stage. The modeling resulted in the addition of a hardening feedback resistor in the 16K remained tentatively unaltered. Subsequent experiments, using the Lawrence Berkeley Laboratories' 88-inch cyclotron to accelerate krypton and oxygen ions, established an upset threshold for the 2K and the 16K without resistance added, as well as a hardening threshold for the 16K with feedback resistance added. Results for the 16K showed it to be hardenable to the higher level than previously published data for other unhardened 16K RAMs. The data agreed fairly well with the modeling results; however, a close look suggests that modification of the simulation methodology is required to accurately predict the resistance necessary to harden the RAM cell

  8. INTRAVAL Finnsjoen Test - modelling results for some tracer experiments

    International Nuclear Information System (INIS)

    Jakob, A.; Hadermann, J.

    1994-09-01

    This report presents the results within Phase II of the INTRAVAL study. Migration experiments performed at the Finnsjoen test site were investigated. The study was done to gain an improved understanding of not only the mechanisms of tracer transport, but also the accuracy and limitations of the model used. The model is based on the concept of a dual porosity medium, taking into account one dimensional advection, longitudinal dispersion, sorption onto the fracture surfaces, diffusion into connected pores of the matrix rock, and sorption onto matrix surfaces. The number of independent water carrying zones, represented either as planar fractures or tubelike veins, may be greater than one, and the sorption processes are described either by linear or non-linear Freundlich isotherms assuming instantaneous sorption equilibrium. The diffusion of the tracer out of the water-carrying zones into connected pore space of the adjacent rock is calculated perpendicular to the direction of the advective/dispersive flow. In the analysis, the fluid flow parameters are calibrated by the measured breakthrough curves for the conservative tracer (iodide). Subsequent fits to the experimental data for the two sorbing tracers strontium and cesium then involve element dependent parameters providing information on the sorption processes and on its representation in the model. The methodology of fixing all parameters except those for sorption with breakthrough curves for non-sorbing tracers generally worked well. The investigation clearly demonstrates the necessity of taking into account pump flow rate variations at both boundaries. If this is not done, reliable conclusions on transport mechanisms or geometrical factors can not be achieved. A two flow path model reproduces the measured data much better than a single flow path concept. (author) figs., tabs., 26 refs

  9. Portfolio Effects of Renewable Energies - Basics, Models, Exemplary Results

    Energy Technology Data Exchange (ETDEWEB)

    Wiese, Andreas; Herrmann, Matthias

    2007-07-01

    The combination of sites and technologies to so-called renewable energy portfolios, which are being developed and implemented under the same financing umbrella, is currently the subject of intense discussion in the finance world. The resulting portfolio effect may allow the prediction of a higher return with the same risk or the same return with a lower risk - always in comparison with the investment in a single project. Models are currently being developed to analyse this subject and derive the portfolio effect. In particular, the effect of the spatial distribution, as well as the effects of using different technologies, suppliers and cost assumptions with different level of uncertainties, are of importance. Wind parks, photovoltaic, biomass, biogas and hydropower are being considered. The status of the model development and first results are being presented in the current paper. In a first example, the portfolio effect has been calculated and analysed using selected parameters for a wind energy portfolio of 39 sites distributed over Europe. Consequently it has been shown that the predicted yield, with the predetermined probabilities between 75 to 90%, is 3 - 8% higher than the sum of the yields for the individual wind parks using the same probabilities. (auth)

  10. Preliminary time-phased TWRS process model results

    International Nuclear Information System (INIS)

    Orme, R.M.

    1995-01-01

    This report documents the first phase of efforts to model the retrieval and processing of Hanford tank waste within the constraints of an assumed tank farm configuration. This time-phased approach simulates a first try at a retrieval sequence, the batching of waste through retrieval facilities, the batching of retrieved waste through enhanced sludge washing, the batching of liquids through pretreatment and low-level waste (LLW) vitrification, and the batching of pretreated solids through high-level waste (HLW) vitrification. The results reflect the outcome of an assumed retrieval sequence that has not been tailored with respect to accepted measures of performance. The batch data, composition variability, and final waste volume projects in this report should be regarded as tentative. Nevertheless, the results provide interesting insights into time-phased processing of the tank waste. Inspection of the composition variability, for example, suggests modifications to the retrieval sequence that will further improve the uniformity of feed to the vitrification facilities. This model will be a valuable tool for evaluating suggested retrieval sequences and establishing a time-phased processing baseline. An official recommendation on tank retrieval sequence will be made in September, 1995

  11. Usefulness of indirect alcohol biomarkers for predicting recidivism of drunk-driving among previously convicted drunk-driving offenders: results from the recidivism of alcohol-impaired driving (ROAD) study.

    Science.gov (United States)

    Maenhout, Thomas M; Poll, Anneleen; Vermassen, Tijl; De Buyzere, Marc L; Delanghe, Joris R

    2014-01-01

    In several European countries, drivers under the influence (DUI), suspected of chronic alcohol abuse are referred for medical and psychological examination. This study (the ROAD study, or Recidivism Of Alcohol-impaired Driving) investigated the usefulness of indirect alcohol biomarkers for predicting drunk-driving recidivism in previously convicted drunk-driving offenders. The ROAD study is a prospective study (2009-13) that was performed on 517 randomly selected drivers in Belgium. They were convicted for drunk-driving for which their licence was confiscated. The initial post-arrest blood samples were collected and analysed for percentage carbohydrate-deficient transferrin (%CDT), transaminsase activities [alanine amino transferase (ALT), aspartate amino transferase (AST)], gamma-glutamyltransferase (γGT) and red cell mean corpuscular volume (MCV). The observation time for each driver was 3 years and dynamic. A logistic regression analysis revealed that ln(%CDT) (P drunk-driving. The ROAD index (which includes ln(%CDT), ln(γGT), -ln(ALT) and the sex of the driver) was calculated and had a significantly higher area under the receiver operator characteristic curve (0.71) than the individual biomarkers for drunk-driving recidivism. Drivers with a high risk of recidivating (ROAD index ≥ 25%; third tertile) could be distinguished from drivers with an intermediate risk (16% ≤ ROAD index drunk-driving. The association with gamma-glutamyltransferase, alanine amino transferase and the sex of the driver could have additional value for identifying drunk-drivers at intermediate risk of recidivism. Non-specific indirect alcohol markers, such as alanine amino transferase, gamma-glutamyltransferase, aspartate amino transferase and red cell mean corpuscular volume have minimal added value to % carbohydrate-deficient transferrin for distinguishing drunk drivers with a low or high risk of recidivism. © 2013 Society for the Study of Addiction.

  12. CT-guided Irreversible Electroporation in an Acute Porcine Liver Model: Effect of Previous Transarterial Iodized Oil Tissue Marking on Technical Parameters, 3D Computed Tomographic Rendering of the Electroporation Zone, and Histopathology

    International Nuclear Information System (INIS)

    Sommer, C. M.; Fritz, S.; Vollherbst, D.; Zelzer, S.; Wachter, M. F.; Bellemann, N.; Gockner, T.; Mokry, T.; Schmitz, A.; Aulmann, S.; Stampfl, U.; Pereira, P.; Kauczor, H. U.; Werner, J.; Radeleff, B. A.

    2015-01-01

    PurposeTo evaluate the effect of previous transarterial iodized oil tissue marking (ITM) on technical parameters, three-dimensional (3D) computed tomographic (CT) rendering of the electroporation zone, and histopathology after CT-guided irreversible electroporation (IRE) in an acute porcine liver model as a potential strategy to improve IRE performance.MethodsAfter Ethics Committee approval was obtained, in five landrace pigs, two IREs of the right and left liver (RL and LL) were performed under CT guidance with identical electroporation parameters. Before IRE, transarterial marking of the LL was performed with iodized oil. Nonenhanced and contrast-enhanced CT examinations followed. One hour after IRE, animals were killed and livers collected. Mean resulting voltage and amperage during IRE were assessed. For 3D CT rendering of the electroporation zone, parameters for size and shape were analyzed. Quantitative data were compared by the Mann–Whitney test. Histopathological differences were assessed.ResultsMean resulting voltage and amperage were 2,545.3 ± 66.0 V and 26.1 ± 1.8 A for RL, and 2,537.3 ± 69.0 V and 27.7 ± 1.8 A for LL without significant differences. Short axis, volume, and sphericity index were 16.5 ± 4.4 mm, 8.6 ± 3.2 cm 3 , and 1.7 ± 0.3 for RL, and 18.2 ± 3.4 mm, 9.8 ± 3.8 cm 3 , and 1.7 ± 0.3 for LL without significant differences. For RL and LL, the electroporation zone consisted of severely widened hepatic sinusoids containing erythrocytes and showed homogeneous apoptosis. For LL, iodized oil could be detected in the center and at the rim of the electroporation zone.ConclusionThere is no adverse effect of previous ITM on technical parameters, 3D CT rendering of the electroporation zone, and histopathology after CT-guided IRE of the liver

  13. CT-guided Irreversible Electroporation in an Acute Porcine Liver Model: Effect of Previous Transarterial Iodized Oil Tissue Marking on Technical Parameters, 3D Computed Tomographic Rendering of the Electroporation Zone, and Histopathology

    Energy Technology Data Exchange (ETDEWEB)

    Sommer, C. M., E-mail: christof.sommer@med.uni-heidelberg.de [University Hospital Heidelberg, Department of Diagnostic and Interventional Radiology (Germany); Fritz, S., E-mail: stefan.fritz@med.uni-heidelberg.de [University Hospital Heidelberg, Department of General Visceral and Transplantation Surgery (Germany); Vollherbst, D., E-mail: dominikvollherbst@web.de [University Hospital Heidelberg, Department of Diagnostic and Interventional Radiology (Germany); Zelzer, S., E-mail: s.zelzer@dkfz-heidelberg.de [German Cancer Research Center (dkfz), Medical and Biological Informatics (Germany); Wachter, M. F., E-mail: fredericwachter@googlemail.com; Bellemann, N., E-mail: nadine.bellemann@med.uni-heidelberg.de; Gockner, T., E-mail: theresa.gockner@med.uni-heidelberg.de; Mokry, T., E-mail: theresa.mokry@med.uni-heidelberg.de; Schmitz, A., E-mail: anne.schmitz@med.uni-heidelberg.de [University Hospital Heidelberg, Department of Diagnostic and Interventional Radiology (Germany); Aulmann, S., E-mail: sebastian.aulmann@mail.com [University Hospital Heidelberg, Department of General Pathology (Germany); Stampfl, U., E-mail: ulrike.stampfl@med.uni-heidelberg.de [University Hospital Heidelberg, Department of Diagnostic and Interventional Radiology (Germany); Pereira, P., E-mail: philippe.pereira@slk-kliniken.de [SLK Kliniken Heilbronn GmbH, Clinic for Radiology, Minimally-invasive Therapies and Nuclear Medicine (Germany); Kauczor, H. U., E-mail: hu.kauczor@med.uni-heidelberg.de [University Hospital Heidelberg, Department of Diagnostic and Interventional Radiology (Germany); Werner, J., E-mail: jens.werner@med.uni-heidelberg.de [University Hospital Heidelberg, Department of General Visceral and Transplantation Surgery (Germany); Radeleff, B. A., E-mail: boris.radeleff@med.uni-heidelberg.de [University Hospital Heidelberg, Department of Diagnostic and Interventional Radiology (Germany)

    2015-02-15

    PurposeTo evaluate the effect of previous transarterial iodized oil tissue marking (ITM) on technical parameters, three-dimensional (3D) computed tomographic (CT) rendering of the electroporation zone, and histopathology after CT-guided irreversible electroporation (IRE) in an acute porcine liver model as a potential strategy to improve IRE performance.MethodsAfter Ethics Committee approval was obtained, in five landrace pigs, two IREs of the right and left liver (RL and LL) were performed under CT guidance with identical electroporation parameters. Before IRE, transarterial marking of the LL was performed with iodized oil. Nonenhanced and contrast-enhanced CT examinations followed. One hour after IRE, animals were killed and livers collected. Mean resulting voltage and amperage during IRE were assessed. For 3D CT rendering of the electroporation zone, parameters for size and shape were analyzed. Quantitative data were compared by the Mann–Whitney test. Histopathological differences were assessed.ResultsMean resulting voltage and amperage were 2,545.3 ± 66.0 V and 26.1 ± 1.8 A for RL, and 2,537.3 ± 69.0 V and 27.7 ± 1.8 A for LL without significant differences. Short axis, volume, and sphericity index were 16.5 ± 4.4 mm, 8.6 ± 3.2 cm{sup 3}, and 1.7 ± 0.3 for RL, and 18.2 ± 3.4 mm, 9.8 ± 3.8 cm{sup 3}, and 1.7 ± 0.3 for LL without significant differences. For RL and LL, the electroporation zone consisted of severely widened hepatic sinusoids containing erythrocytes and showed homogeneous apoptosis. For LL, iodized oil could be detected in the center and at the rim of the electroporation zone.ConclusionThere is no adverse effect of previous ITM on technical parameters, 3D CT rendering of the electroporation zone, and histopathology after CT-guided IRE of the liver.

  14. Graph and model transformation tools for model migration : empirical results from the transformation tool contest

    NARCIS (Netherlands)

    Rose, L.M.; Herrmannsdoerfer, M.; Mazanek, S.; Van Gorp, P.M.E.; Buchwald, S.; Horn, T.; Kalnina, E.; Koch, A.; Lano, K.; Schätz, B.; Wimmer, M.

    2014-01-01

    We describe the results of the Transformation Tool Contest 2010 workshop, in which nine graph and model transformation tools were compared for specifying model migration. The model migration problem—migration of UML activity diagrams from version 1.4 to version 2.2—is non-trivial and practically

  15. Preoperative screening: value of previous tests.

    Science.gov (United States)

    Macpherson, D S; Snow, R; Lofgren, R P

    1990-12-15

    To determine the frequency of tests done in the year before elective surgery that might substitute for preoperative screening tests and to determine the frequency of test results that change from a normal value to a value likely to alter perioperative management. Retrospective cohort analysis of computerized laboratory data (complete blood count, sodium, potassium, and creatinine levels, prothrombin time, and partial thromboplastin time). Urban tertiary care Veterans Affairs Hospital. Consecutive sample of 1109 patients who had elective surgery in 1988. At admission, 7549 preoperative tests were done, 47% of which duplicated tests performed in the previous year. Of 3096 previous results that were normal as defined by hospital reference range and done closest to the time of but before admission (median interval, 2 months), 13 (0.4%; 95% CI, 0.2% to 0.7%), repeat values were outside a range considered acceptable for surgery. Most of the abnormalities were predictable from the patient's history, and most were not noted in the medical record. Of 461 previous tests that were abnormal, 78 (17%; CI, 13% to 20%) repeat values at admission were outside a range considered acceptable for surgery (P less than 0.001, frequency of clinically important abnormalities of patients with normal previous results with those with abnormal previous results). Physicians evaluating patients preoperatively could safely substitute the previous test results analyzed in this study for preoperative screening tests if the previous tests are normal and no obvious indication for retesting is present.

  16. Analytical results for a stochastic model of gene expression with arbitrary partitioning of proteins

    Science.gov (United States)

    Tschirhart, Hugo; Platini, Thierry

    2018-05-01

    In biophysics, the search for analytical solutions of stochastic models of cellular processes is often a challenging task. In recent work on models of gene expression, it was shown that a mapping based on partitioning of Poisson arrivals (PPA-mapping) can lead to exact solutions for previously unsolved problems. While the approach can be used in general when the model involves Poisson processes corresponding to creation or degradation, current applications of the method and new results derived using it have been limited to date. In this paper, we present the exact solution of a variation of the two-stage model of gene expression (with time dependent transition rates) describing the arbitrary partitioning of proteins. The methodology proposed makes full use of the PPA-mapping by transforming the original problem into a new process describing the evolution of three biological switches. Based on a succession of transformations, the method leads to a hierarchy of reduced models. We give an integral expression of the time dependent generating function as well as explicit results for the mean, variance, and correlation function. Finally, we discuss how results for time dependent parameters can be extended to the three-stage model and used to make inferences about models with parameter fluctuations induced by hidden stochastic variables.

  17. Further Results on Dynamic Additive Hazard Rate Model

    Directory of Open Access Journals (Sweden)

    Zhengcheng Zhang

    2014-01-01

    Full Text Available In the past, the proportional and additive hazard rate models have been investigated in the works. Nanda and Das (2011 introduced and studied the dynamic proportional (reversed hazard rate model. In this paper we study the dynamic additive hazard rate model, and investigate its aging properties for different aging classes. The closure of the model under some stochastic orders has also been investigated. Some examples are also given to illustrate different aging properties and stochastic comparisons of the model.

  18. Extending positive CLASS results across multiple instructors and multiple classes of Modeling Instruction

    Science.gov (United States)

    Brewe, Eric; Traxler, Adrienne; de la Garza, Jorge; Kramer, Laird H.

    2013-12-01

    We report on a multiyear study of student attitudes measured with the Colorado Learning Attitudes about Science Survey in calculus-based introductory physics taught with the Modeling Instruction curriculum. We find that five of six instructors and eight of nine sections using Modeling Instruction showed significantly improved attitudes from pre- to postcourse. Cohen’s d effect sizes range from 0.08 to 0.95 for individual instructors. The average effect was d=0.45, with a 95% confidence interval of (0.26-0.64). These results build on previously published results showing positive shifts in attitudes from Modeling Instruction classes. We interpret these data in light of other published positive attitudinal shifts and explore mechanistic explanations for similarities and differences with other published positive shifts.

  19. Extending positive CLASS results across multiple instructors and multiple classes of Modeling Instruction

    Directory of Open Access Journals (Sweden)

    Eric Brewe

    2013-10-01

    Full Text Available We report on a multiyear study of student attitudes measured with the Colorado Learning Attitudes about Science Survey in calculus-based introductory physics taught with the Modeling Instruction curriculum. We find that five of six instructors and eight of nine sections using Modeling Instruction showed significantly improved attitudes from pre- to postcourse. Cohen’s d effect sizes range from 0.08 to 0.95 for individual instructors. The average effect was d=0.45, with a 95% confidence interval of (0.26–0.64. These results build on previously published results showing positive shifts in attitudes from Modeling Instruction classes. We interpret these data in light of other published positive attitudinal shifts and explore mechanistic explanations for similarities and differences with other published positive shifts.

  20. VNIR spectral modeling of Mars analogue rocks: first results

    Science.gov (United States)

    Pompilio, L.; Roush, T.; Pedrazzi, G.; Sgavetti, M.

    Knowledge regarding the surface composition of Mars and other bodies of the inner solar system is fundamental to understanding of their origin, evolution, and internal structures. Technological improvements of remote sensors and associated implications for planetary studies have encouraged increased laboratory and field spectroscopy research to model the spectral behavior of terrestrial analogues for planetary surfaces. This approach has proven useful during Martian surface and orbital missions, and petrologic studies of Martian SNC meteorites. Thermal emission data were used to suggest two lithologies occurring on Mars surface: basalt with abundant plagioclase and clinopyroxene and andesite, dominated by plagioclase and volcanic glass [1,2]. Weathered basalt has been suggested as an alternative to the andesite interpretation [3,4]. Orbital VNIR spectral imaging data also suggest the crust is dominantly basaltic, chiefly feldspar and pyroxene [5,6]. A few outcrops of ancient crust have higher concentrations of olivine and low-Ca pyroxene, and have been interpreted as cumulates [6]. Based upon these orbital observations future lander/rover missions can be expected to encounter particulate soils, rocks, and rock outcrops. Approaches to qualitative and quantitative analysis of remotely-acquired spectra have been successfully used to infer the presence and abundance of minerals and to discover compositionally associated spectral trends [7-9]. Both empirical [10] and mathematical [e.g. 11-13] methods have been applied, typically with full compositional knowledge, to chiefly particulate samples and as a result cannot be considered as objective techniques for predicting the compositional information, especially for understanding the spectral behavior of rocks. Extending the compositional modeling efforts to include more rocks and developing objective criteria in the modeling are the next required steps. This is the focus of the present investigation. We present results of

  1. Tapering of the CHESS-APS undulator: Results and modelling

    International Nuclear Information System (INIS)

    Lai, B.; Viccaro, P.J.; Dejus, R.; Gluskin, E.; Yun, W.B.; McNulty, I.; Henderson, C.; White, J.; Shen, Q.; Finkelstein, K.

    1992-01-01

    When the magnetic gap of an undulator is tapered along the beam direction, the slowly varying peak field B o introduces a spread in the value of the deflection parameter K. The result is a broad energy-band undulator that still maintains high degree of spatial collimation. These properties are very useful for EXAFS and energy dispersive techniques. We have characterized the CHESS-APS undulator (1 υ = 3.3cm) at one tapered configuration (10% change of the magnetic gap from one end of the undulator to the other). Spatial distribution and energy spectra of the first three harmonics through a pinhole were measured. The on-axis first harmonic width increased from 0.27 keV to 0.61 keV (FWHM) at the central energy of E 1 = 6.6 keV (K average = 0.69). Broadening in the angular distribution due to tapering was minimal. These results will be compared with computer modelling which simulates the actual electron trajectory in the tapered case

  2. Conception of spent fuel and radioactive wastes management in Poland based on the results of the previous work performed in the frames of Governmental Strategic Programme realised under patronate of National Atomic Energy Agency

    International Nuclear Information System (INIS)

    Wlodarski, J.; Chwaszczewski, S.; Slizowski, K.; Frankowski, Z.

    1999-01-01

    About 300 cubic meters of solid and solidified radioactive wastes of low and medium activity are produced each year in Poland. Such materials, after processing, are stored in the Institute of Atomic Energy at Swierk or in the National Repository for Radioactive Wastes in Rozan. About 6000 spent fuel elements are temporarily stored in water pools at Swierk. Assumptions and strategy of future spent fuel and radioactive wastes management are presented taking into account operation of the first nuclear power plants (after 2010). Then Governmental Strategic Programme (GSP) for the year 1997-1999 concerning such topic is described and some results of the work performed in the frames of the GSP are given

  3. Intensive versus Guideline Blood Pressure and Lipid Lowering in Patients with Previous Stroke: Main Results from the Pilot ‘Prevention of Decline in Cognition after Stroke Trial’ (PODCAST) Randomised Controlled Trial

    Science.gov (United States)

    Scutt, Polly; Blackburn, Daniel J.; Ankolekar, Sandeep; Krishnan, Kailash; Ballard, Clive; Burns, Alistair; Mant, Jonathan; Passmore, Peter; Pocock, Stuart; Reckless, John; Sprigg, Nikola; Stewart, Rob; Wardlaw, Joanna M.; Ford, Gary A.

    2017-01-01

    Background Stroke is associated with the development of cognitive impairment and dementia. We assessed the effect of intensive blood pressure (BP) and/or lipid lowering on cognitive outcomes in patients with recent stroke in a pilot trial. Methods In a multicentre, partial-factorial trial, patients with recent stroke, absence of dementia, and systolic BP (SBP) 125–170 mmHg were assigned randomly to at least 6 months of intensive (target SBP Addenbrooke’s Cognitive Examination-Revised (ACE-R). Results We enrolled 83 patients, mean age 74.0 (6.8) years, and median 4.5 months after stroke. The median follow-up was 24 months (range 1–48). Mean BP was significantly reduced with intensive compared to guideline treatment (difference –10·6/–5·5 mmHg; pcognition, intensive BP and lipid lowering were feasible and safe, but did not alter cognition over two years. The association between intensive lipid lowering and improved scores for some secondary outcomes suggests further trials are warranted. Trial Registration ISRCTN ISRCTN85562386 PMID:28095412

  4. Demixing in a metal halide lamp, results from modelling

    NARCIS (Netherlands)

    Beks, M.L.; Hartgers, A.; Mullen, van der J.J.A.M.

    2006-01-01

    Convection and diffusion in the discharge region of a metal halide lamp is studied using a computer model built with the plasma modeling package Plasimo. A model lamp contg. mercury and sodium iodide is studied. The effects of the total lamp pressure on the degree of segregation of the light

  5. A Duality Result for the Generalized Erlang Risk Model

    Directory of Open Access Journals (Sweden)

    Lanpeng Ji

    2014-11-01

    Full Text Available In this article, we consider the generalized Erlang risk model and its dual model. By using a conditional measure-preserving correspondence between the two models, we derive an identity for two interesting conditional probabilities. Applications to the discounted joint density of the surplus prior to ruin and the deficit at ruin are also discussed.

  6. Waste glass corrosion modeling: Comparison with experimental results

    International Nuclear Information System (INIS)

    Bourcier, W.L.

    1994-01-01

    Models for borosilicate glass dissolution must account for the processes of (1) kinetically-controlled network dissolution, (2) precipitation of secondary phases, (3) ion exchange, (4) rate-limiting diffusive transport of silica through a hydrous surface reaction layer, and (5) specific glass surface interactions with dissolved cations and anions. Current long-term corrosion models for borosilicate glass employ a rate equation consistent with transition state theory embodied in a geochemical reaction-path modeling program that calculates aqueous phase speciation and mineral precipitation/dissolution. These models are currently under development. Future experimental and modeling work to better quantify the rate-controlling processes and validate these models are necessary before the models can be used in repository performance assessment calculations

  7. Argonne Fuel Cycle Facility ventilation system -- modeling and results

    International Nuclear Information System (INIS)

    Mohr, D.; Feldman, E.E.; Danielson, W.F.

    1995-01-01

    This paper describes an integrated study of the Argonne-West Fuel Cycle Facility (FCF) interconnected ventilation systems during various operations. Analyses and test results include first a nominal condition reflecting balanced pressures and flows followed by several infrequent and off-normal scenarios. This effort is the first study of the FCF ventilation systems as an integrated network wherein the hydraulic effects of all major air systems have been analyzed and tested. The FCF building consists of many interconnected regions in which nuclear fuel is handled, transported and reprocessed. The ventilation systems comprise a large number of ducts, fans, dampers, and filters which together must provide clean, properly conditioned air to the worker occupied spaces of the facility while preventing the spread of airborne radioactive materials to clean am-as or the atmosphere. This objective is achieved by keeping the FCF building at a partial vacuum in which the contaminated areas are kept at lower pressures than the other worker occupied spaces. The ventilation systems of FCF and the EBR-II reactor are analyzed as an integrated totality, as demonstrated. We then developed the network model shown in Fig. 2 for the TORAC code. The scope of this study was to assess the measured results from the acceptance/flow balancing testing and to predict the effects of power failures, hatch and door openings, single-failure faulted conditions, EBR-II isolation, and other infrequent operations. The studies show that the FCF ventilation systems am very controllable and remain stable following off-normal events. In addition, the FCF ventilation system complex is essentially immune to reverse flows and spread of contamination to clean areas during normal and off-normal operation

  8. ExEP yield modeling tool and validation test results

    Science.gov (United States)

    Morgan, Rhonda; Turmon, Michael; Delacroix, Christian; Savransky, Dmitry; Garrett, Daniel; Lowrance, Patrick; Liu, Xiang Cate; Nunez, Paul

    2017-09-01

    EXOSIMS is an open-source simulation tool for parametric modeling of the detection yield and characterization of exoplanets. EXOSIMS has been adopted by the Exoplanet Exploration Programs Standards Definition and Evaluation Team (ExSDET) as a common mechanism for comparison of exoplanet mission concept studies. To ensure trustworthiness of the tool, we developed a validation test plan that leverages the Python-language unit-test framework, utilizes integration tests for selected module interactions, and performs end-to-end crossvalidation with other yield tools. This paper presents the test methods and results, with the physics-based tests such as photometry and integration time calculation treated in detail and the functional tests treated summarily. The test case utilized a 4m unobscured telescope with an idealized coronagraph and an exoplanet population from the IPAC radial velocity (RV) exoplanet catalog. The known RV planets were set at quadrature to allow deterministic validation of the calculation of physical parameters, such as working angle, photon counts and integration time. The observing keepout region was tested by generating plots and movies of the targets and the keepout zone over a year. Although the keepout integration test required the interpretation of a user, the test revealed problems in the L2 halo orbit and the parameterization of keepout applied to some solar system bodies, which the development team was able to address. The validation testing of EXOSIMS was performed iteratively with the developers of EXOSIMS and resulted in a more robust, stable, and trustworthy tool that the exoplanet community can use to simulate exoplanet direct-detection missions from probe class, to WFIRST, up to large mission concepts such as HabEx and LUVOIR.

  9. Final model independent result of DAMA/LIBRA-phase1

    Energy Technology Data Exchange (ETDEWEB)

    Bernabei, R.; D' Angelo, S.; Di Marco, A. [Universita di Roma ' ' Tor Vergata' ' , Dipartimento di Fisica, Rome (Italy); INFN, sez. Roma ' ' Tor Vergata' ' , Rome (Italy); Belli, P. [INFN, sez. Roma ' ' Tor Vergata' ' , Rome (Italy); Cappella, F.; D' Angelo, A.; Prosperi, D. [Universita di Roma ' ' La Sapienza' ' , Dipartimento di Fisica, Rome (Italy); INFN, sez. Roma, Rome (Italy); Caracciolo, V.; Castellano, S.; Cerulli, R. [INFN, Laboratori Nazionali del Gran Sasso, Assergi (Italy); Dai, C.J.; He, H.L.; Kuang, H.H.; Ma, X.H.; Sheng, X.D.; Wang, R.G. [Chinese Academy, IHEP, Beijing (China); Incicchitti, A. [INFN, sez. Roma, Rome (Italy); Montecchia, F. [INFN, sez. Roma ' ' Tor Vergata' ' , Rome (Italy); Universita di Roma ' ' Tor Vergata' ' , Dipartimento di Ingegneria Civile e Ingegneria Informatica, Rome (Italy); Ye, Z.P. [Chinese Academy, IHEP, Beijing (China); University of Jing Gangshan, Jiangxi (China)

    2013-12-15

    The results obtained with the total exposure of 1.04 ton x yr collected by DAMA/LIBRA-phase1 deep underground at the Gran Sasso National Laboratory (LNGS) of the I.N.F.N. during 7 annual cycles (i.e. adding a further 0.17 ton x yr exposure) are presented. The DAMA/LIBRA-phase1 data give evidence for the presence of Dark Matter (DM) particles in the galactic halo, on the basis of the exploited model independent DM annual modulation signature by using highly radio-pure NaI(Tl) target, at 7.5{sigma} C.L. Including also the first generation DAMA/NaI experiment (cumulative exposure 1.33 ton x yr, corresponding to 14 annual cycles), the C.L. is 9.3{sigma} and the modulation amplitude of the single-hit events in the (2-6) keV energy interval is: (0.0112{+-}0.0012) cpd/kg/keV; the measured phase is (144{+-}7) days and the measured period is (0.998{+-}0.002) yr, values well in agreement with those expected for DM particles. No systematic or side reaction able to mimic the exploited DM signature has been found or suggested by anyone over more than a decade. (orig.)

  10. Innovation ecosystem model for commercialization of research results

    Directory of Open Access Journals (Sweden)

    Vlăduţ Gabriel

    2017-07-01

    Full Text Available Innovation means Creativity and Added value recognise by the market. The first step in creating a sustainable commercialization of research results, Technological Transfer – TT mechanism, on one hand is to define the “technology” which will be transferred and on other hand to define the context in which the TT mechanism work, the ecosystem. The focus must be set on technology as an entity, not as a science or a study of the practical industrial arts and certainly not any specific applied science. The transfer object, the technology, must rely on a subjectively determined but specifiable set of processes and products. Focusing on the product is not sufficient to the transfer and diffusion of technology. It is not merely the product that is transferred but also knowledge of its use and application. The innovation ecosystem model brings together new companies, experienced business leaders, researchers, government officials, established technology companies, and investors. This environment provides those new companies with a wealth of technical expertise, business experience, and access to capital that supports innovation in the early stages of growth.

  11. Results from the Savannah River Laboratory model validation workshop

    International Nuclear Information System (INIS)

    Pepper, D.W.

    1981-01-01

    To evaluate existing and newly developed air pollution models used in DOE-funded laboratories, the Savannah River Laboratory sponsored a model validation workshop. The workshop used Kr-85 measurements and meteorology data obtained at SRL during 1975 to 1977. Individual laboratories used models to calculate daily, weekly, monthly or annual test periods. Cumulative integrated air concentrations were reported at each grid point and at each of the eight sampler locations

  12. Waste glass corrosion modeling: Comparison with experimental results

    International Nuclear Information System (INIS)

    Bourcier, W.L.

    1993-11-01

    A chemical model of glass corrosion will be used to predict the rates of release of radionuclides from borosilicate glass waste forms in high-level waste repositories. The model will be used both to calculate the rate of degradation of the glass, and also to predict the effects of chemical interactions between the glass and repository materials such as spent fuel, canister and container materials, backfill, cements, grouts, and others. Coupling between the degradation processes affecting all these materials is expected. Models for borosilicate glass dissolution must account for the processes of (1) kinetically-controlled network dissolution, (2) precipitation of secondary phases, (3) ion exchange, (4) rate-limiting diffusive transport of silica through a hydrous surface reaction layer, and (5) specific glass surface interactions with dissolved cations and anions. Current long-term corrosion models for borosilicate glass employ a rate equation consistent with transition state theory embodied in a geochemical reaction-path modeling program that calculates aqueous phase speciation and mineral precipitation/dissolution. These models are currently under development. Future experimental and modeling work to better quantify the rate-controlling processes and validate these models are necessary before the models can be used in repository performance assessment calculations

  13. Regionalization of climate model results for the North Sea

    Energy Technology Data Exchange (ETDEWEB)

    Kauker, F.

    1999-07-01

    A dynamical downscaling is presented that allows an estimation of potential effects of climate change on the North Sea. Therefore, the ocean general circulation model OPYC is adapted for application on a shelf by adding a lateral boundary formulation and a tide model. In this set-up the model is forced, first, with data from the ECMWF reanalysis for model validation and the study of the natural variability, and, second, with data from climate change experiments to estimate the effects of climate change on the North Sea. (orig.)

  14. results

    Directory of Open Access Journals (Sweden)

    Salabura Piotr

    2017-01-01

    Full Text Available HADES experiment at GSI is the only high precision experiment probing nuclear matter in the beam energy range of a few AGeV. Pion, proton and ion beams are used to study rare dielectron and strangeness probes to diagnose properties of strongly interacting matter in this energy regime. Selected results from p + A and A + A collisions are presented and discussed.

  15. Spinal cord stimulation: modeling results and clinical data

    NARCIS (Netherlands)

    Struijk, Johannes J.; Struijk, J.J.; Holsheimer, J.; Barolat, Giancarlo; He, Jiping

    1992-01-01

    The potential distribution in volume couductor models of the spinal cord at cervical, midthoracic and lowthoracic levels, due to epidural stimulation, was calculated. Treshold stimuli of modeled myelhated dorsal column and dorsal root fibers were calculated and were compared with perception

  16. How to: understanding SWAT model uncertainty relative to measured results

    Science.gov (United States)

    Watershed models are being relied upon to contribute to most policy-making decisions of watershed management, and the demand for an accurate accounting of complete model uncertainty is rising. Generalized likelihood uncertainty estimation (GLUE) is a widely used method for quantifying uncertainty i...

  17. Urban traffic noise assessment by combining measurement and model results

    NARCIS (Netherlands)

    Eerden, F.J.M. van der; Graafland, F.; Wessels, P.W.; Basten, T.G.H.

    2013-01-01

    A model based monitoring system is applied on a local scale in an urban area to obtain a better understanding of the traffic noise situation. The system consists of a scalable sensor network and an engineering model. A better understanding is needed to take appropriate and cost efficient measures,

  18. Noise and dose modeling for pediatric CT optimization: preliminary results

    International Nuclear Information System (INIS)

    Miller Clemente, Rafael A.; Perez Diaz, Marlen; Mora Reyes, Yudel; Rodriguez Garlobo, Maikel; Castillo Salazar, Rafael

    2008-01-01

    Full text: A Multiple Linear Regression Model was developed to predict noise and dose in computed tomography pediatric imaging for head and abdominal examinations. Relative values of Noise and Volumetric Computed Tomography Dose Index was used to estimate de model respectively. 54 images of physical phantoms were performed. Independent variables considered included: phantom diameter, tube current and kilovolts, x ray beam collimation, reconstruction diameter and equipment's post processing filters. Predicted values show good agreement with measurements, which were better in noise model (R 2 adjusted =0.953) than the dose model (R 2 adjusted =0.744). Tube current, object diameter, beam collimation and reconstruction filter were identified as the most influencing factors in models. (author)

  19. Exact results for quantum chaotic systems and one-dimensional fermions from matrix models

    International Nuclear Information System (INIS)

    Simons, B.D.; Lee, P.A.; Altshuler, B.L.

    1993-01-01

    We demonstrate a striking connection between the universal parametric correlations of the spectra of quantum chaotic systems and a class of integrable quantum hamiltonians. We begin by deriving a non-perturbative expression for the universal m-point correlation function of the spectra of random matrix ensembles in terms of a non-linear supermatrix σ-model. These results are shown to coincide with those from previous studies of weakly disordered metallic systems. We then introduce a continuous matrix model which describes the quantum mechanics of the Sutherland hamiltonian describing particles interacting through an inverse-square pairwise potential. We demonstrate that a field theoretic approach can be employed to determine exact analytical expressions for correlations of the quantum hamiltonian. The results, which are expressed in terms of a non-linear σ-model, are shown to coincide with those for analogous correlation functions of random matrix ensembles after an appropriate change of variables. We also discuss possible generalizations of the matrix model to higher dimensions. These results reveal a common mathematical structure which underlies branches of theoretical physics ranging from continuous matrix models to strongly interacting quantum hamiltonians, and universalities in the spectra of quantum chaotic systems. (orig.)

  20. Results on a Binding Neuron Model and Their Implications for Modified Hourglass Model for Neuronal Network

    Directory of Open Access Journals (Sweden)

    Viswanathan Arunachalam

    2013-01-01

    Full Text Available The classical models of single neuron like Hodgkin-Huxley point neuron or leaky integrate and fire neuron assume the influence of postsynaptic potentials to last till the neuron fires. Vidybida (2008 in a refreshing departure has proposed models for binding neurons in which the trace of an input is remembered only for a finite fixed period of time after which it is forgotten. The binding neurons conform to the behaviour of real neurons and are applicable in constructing fast recurrent networks for computer modeling. This paper develops explicitly several useful results for a binding neuron like the firing time distribution and other statistical characteristics. We also discuss the applicability of the developed results in constructing a modified hourglass network model in which there are interconnected neurons with excitatory as well as inhibitory inputs. Limited simulation results of the hourglass network are presented.

  1. Verification of Simulation Results Using Scale Model Flight Test Trajectories

    National Research Council Canada - National Science Library

    Obermark, Jeff

    2004-01-01

    .... A second compromise scaling law was investigated as a possible improvement. For ejector-driven events at minimum sideslip, the most important variables for scale model construction are the mass moment of inertia and ejector...

  2. Box photosynthesis modeling results for WRF/CMAQ LSM

    Data.gov (United States)

    U.S. Environmental Protection Agency — Box Photosynthesis model simulations for latent heat and ozone at 6 different FLUXNET sites. This dataset is associated with the following publication: Ran, L., J....

  3. Some Econometric Results for the Blanchard-Watson Bubble Model

    DEFF Research Database (Denmark)

    Johansen, Soren; Lange, Theis

    The purpose of the present paper is to analyse a simple bubble model suggested by Blanchard and Watson. The model is defined by y(t) =s(t)¿y(t-1)+e(t), t=1,…,n, where s(t) is an i.i.d. binary variable with p=P(s(t)=1), independent of e(t) i.i.d. with mean zero and finite variance. We take ¿>1 so...

  4. The 3D Reference Earth Model: Status and Preliminary Results

    Science.gov (United States)

    Moulik, P.; Lekic, V.; Romanowicz, B. A.

    2017-12-01

    In the 20th century, seismologists constructed models of how average physical properties (e.g. density, rigidity, compressibility, anisotropy) vary with depth in the Earth's interior. These one-dimensional (1D) reference Earth models (e.g. PREM) have proven indispensable in earthquake location, imaging of interior structure, understanding material properties under extreme conditions, and as a reference in other fields, such as particle physics and astronomy. Over the past three decades, new datasets motivated more sophisticated efforts that yielded models of how properties vary both laterally and with depth in the Earth's interior. Though these three-dimensional (3D) models exhibit compelling similarities at large scales, differences in the methodology, representation of structure, and dataset upon which they are based, have prevented the creation of 3D community reference models. As part of the REM-3D project, we are compiling and reconciling reference seismic datasets of body wave travel-time measurements, fundamental mode and overtone surface wave dispersion measurements, and normal mode frequencies and splitting functions. These reference datasets are being inverted for a long-wavelength, 3D reference Earth model that describes the robust long-wavelength features of mantle heterogeneity. As a community reference model with fully quantified uncertainties and tradeoffs and an associated publically available dataset, REM-3D will facilitate Earth imaging studies, earthquake characterization, inferences on temperature and composition in the deep interior, and be of improved utility to emerging scientific endeavors, such as neutrino geoscience. Here, we summarize progress made in the construction of the reference long period dataset and present a preliminary version of REM-3D in the upper-mantle. In order to determine the level of detail warranted for inclusion in REM-3D, we analyze the spectrum of discrepancies between models inverted with different subsets of the

  5. The animal model determines the results of Aeromonas virulence factors

    Directory of Open Access Journals (Sweden)

    Alejandro Romero

    2016-10-01

    Full Text Available The selection of an experimental animal model is of great importance in the study of bacterial virulence factors. Here, a bath infection of zebrafish larvae is proposed as an alternative model to study the virulence factors of A. hydrophila. Intraperitoneal infections in mice and trout were compared with bath infections in zebrafish larvae using specific mutants. The great advantage of this model is that bath immersion mimics the natural route of infection, and injury to the tail also provides a natural portal of entry for the bacteria. The implication of T3SS in the virulence of A. hydrophila was analysed using the AH-1::aopB mutant. This mutant was less virulent than the wild-type strain when inoculated into zebrafish larvae, as described in other vertebrates. However, the zebrafish model exhibited slight differences in mortality kinetics only observed using invertebrate models. Infections using the mutant AH-1∆vapA lacking the gene coding for the surface S-layer suggested that this protein was not totally necessary to the bacteria once it was inside the host, but it contributed to the inflammatory response. Only when healthy zebrafish larvae were infected did the mutant produce less mortality than the wild type. Variations between models were evidenced using the AH-1∆rmlB, which lacks the O-antigen lipopolysaccharide (LPS, and the AH-1∆wahD, which lacks the O-antigen LPS and part of the LPS outer-core. Both mutants showed decreased mortality in all of the animal models, but the differences between them were only observed in injured zebrafish larvae, suggesting that residues from the LPS outer core must be important for virulence. The greatest differences were observed using the AH-1ΔFlaB-J (lacking polar flagella and unable to swim and the AH-1::motX (non-motile but producing flagella. They were as pathogenic as the wild-type strain when injected into mice and trout, but no mortalities were registered in zebrafish larvae. This study

  6. Recent shell-model results for exotic nuclei

    Directory of Open Access Journals (Sweden)

    Utsuno Yusuke

    2014-03-01

    Full Text Available We report on our recent advancement in the shell model and its applications to exotic nuclei, focusing on the shell evolution and large-scale calculations with the Monte Carlo shell model (MCSM. First, we test the validity of the monopole-based universal interaction (VMU as a shell-model interaction by performing large-scale shell-model calculations in two different mass regions using effective interactions which partly comprise VMU. Those calculations are successful and provide a deeper insight into the shell evolution beyond the single-particle model, in particular showing that the evolution of the spin-orbit splitting due to the tensor force plays a decisive role in the structure of the neutron-rich N ∼ 28 region and antimony isotopes. Next, we give a brief overview of recent developments in MCSM, and show that it is applicable to exotic nuclei that involve many valence orbits. As an example of its applications to exotic nuclei, shape coexistence in 32Mg is examined.

  7. A model for hot electron phenomena: Theory and general results

    International Nuclear Information System (INIS)

    Carrillo, J.L.; Rodriquez, M.A.

    1988-10-01

    We propose a model for the description of the hot electron phenomena in semiconductors. Based on this model we are able to reproduce accurately the main characteristics observed in experiments of electric field transport, optical absorption, steady state photoluminescence and relaxation process. Our theory does not contain free nor adjustable parameters, it is very fast computerwise, and incorporates the main collision mechanisms including screening and phonon heating effects. Our description on a set of nonlinear rate equations in which the interactions are represented by coupling coefficients or effective frequencies. We calculate three coefficients from the characteristic constants and the band structure of the material. (author). 22 refs, 5 figs, 1 tab

  8. Results from Development of Model Specifications for Multifamily Energy Retrofits

    Energy Technology Data Exchange (ETDEWEB)

    Brozyna, K.

    2012-08-01

    Specifications, modeled after CSI MasterFormat, provide the trade contractors and builders with requirements and recommendations on specific building materials, components and industry practices that comply with the expectations and intent of the requirements within the various funding programs associated with a project. The goal is to create a greater level of consistency in execution of energy efficiency retrofits measures across the multiple regions a developer may work. IBACOS and Mercy Housing developed sample model specifications based on a common building construction type that Mercy Housing encounters.

  9. Results From Development of Model Specifications for Multifamily Energy Retrofits

    Energy Technology Data Exchange (ETDEWEB)

    Brozyna, Kevin [IBACOS, Inc., Pittsburgh, PA (United States)

    2012-08-01

    Specifications, modeled after CSI MasterFormat, provide the trade contractors and builders with requirements and recommendations on specific building materials, components and industry practices that comply with the expectations and intent of the requirements within the various funding programs associated with a project. The goal is to create a greater level of consistency in execution of energy efficiency retrofits measures across the multiple regions a developer may work. IBACOS and Mercy Housing developed sample model specifications based on a common building construction type that Mercy Housing encounters.

  10. Analytical results for the Sznajd model of opinion formation

    Czech Academy of Sciences Publication Activity Database

    Slanina, František; Lavička, H.

    2003-01-01

    Roč. 35, - (2003), s. 279-288 ISSN 1434-6028 R&D Projects: GA ČR GA202/01/1091 Institutional research plan: CEZ:AV0Z1010914 Keywords : agent models * sociophysics Subject RIV: BE - Theoretical Physics Impact factor: 1.457, year: 2003

  11. Some Results On The Modelling Of TSS Manufacturing Lines

    Directory of Open Access Journals (Sweden)

    Viorel MÎNZU

    2000-12-01

    Full Text Available This paper deals with the modelling of a particular class of manufacturing lines, governed by a decentralised control strategy so that they balance themselves. Such lines are known as “bucket brigades” and also as “TSS lines”, after their first implementation, at Toyota, in the 70’s. A first study of their behaviour was based upon modelling as stochastic dynamic systems, which emphasised, in the frame of the so-called “Normative Model”, a sufficient condition for self-balancing, that means for autonomous functioning at a steady production rate (stationary behaviour. Under some particular conditions, a simulation analysis of TSS lines could be made on non-linear block diagrams, showing that the state trajectories are piecewise continuous in between occurrences of certain discrete events, which determine their discontinuity. TSS lines may therefore be modelled as hybrid dynamic systems, more specific, with autonomous switching and autonomous impulses (jumps. A stability analysis of such manufacturing lines is allowed by modelling them as hybrid dynamic systems with discontinuous motions.

  12. Recent numerical results on the two dimensional Hubbard model

    Energy Technology Data Exchange (ETDEWEB)

    Parola, A.; Sorella, S.; Baroni, S.; Car, R.; Parrinello, M.; Tosatti, E. (SISSA, Trieste (Italy))

    1989-12-01

    A new method for simulating strongly correlated fermionic systems, has been applied to the study of the ground state properties of the 2D Hubbard model at various fillings. Comparison has been made with exact diagonalizations in the 4 x 4 lattices where very good agreement has been verified in all the correlation functions which have been studied: charge, magnetization and momentum distribution. (orig.).

  13. Recent numerical results on the two dimensional Hubbard model

    International Nuclear Information System (INIS)

    Parola, A.; Sorella, S.; Baroni, S.; Car, R.; Parrinello, M.; Tosatti, E.

    1989-01-01

    This paper reports a new method for simulating strongly correlated fermionic systems applied to the study of the ground state properties of the 2D Hubbard model at various fillings. Comparison has been made with exact diagonalizations in the 4 x 4 lattices where very good agreement has been verified in all the correlation functions which have been studied: charge, magnetization and momentum distribution

  14. Some rigorous results on the Hopfield neural network model

    International Nuclear Information System (INIS)

    Koch, H.; Piasko, J.

    1989-01-01

    The authors analyze the thermal equilibrium distribution of 2 p mean field variables for the Hopfield model with p stored patterns, in the case where 2 p is small compared to the number of spins. In particular, they give a full description of the free energy density in the thermodynamic limit, and of the so-called symmetric solutions for the mean field equations

  15. The thermochemical, two-phase dynamics of subduction zones: results from new, fully coupled models

    Science.gov (United States)

    Rees Jones, D. W.; Katz, R. F.; May, D.; Tian, M.; Rudge, J. F.

    2017-12-01

    Subduction zones are responsible for most of Earth's subaerial volcanism. However, previous geodynamic modelling of subduction zones has largely neglected magmatism. We previously showed that magmatism has a significant thermal impact, by advecting sensible heat into the lithosphere beneath arc volcanos [1]. Inclusion of this effect helps reconcile subduction zone models with petrological and heat flow observations. Many important questions remain, including how magma-mantle dynamics of subduction zones affects the position of arc volcanos and the character of their lavas. In this presentation, we employ a fully coupled, thermochemical, two-phase flow theory to investigate the dynamics of subduction zones. We present the first results from our new software (SubFUSc), which solves the coupled equations governing conservation of mass, momentum, energy and chemical species. The presence and migration of partial melts affect permeability and mantle viscosity (both directly and through their thermal impact); these, in turn, feed back on the magma-mantle flow. Thus our fully coupled modelling improves upon previous two-phase models that decoupled the governing equations and fixed the thermal structure [2]. To capture phase change, we use a novel, simplified model of the mantle melting in the presence of volatile species. As in the natural system, volatiles are associated with low-degree melting at temperatures beneath the anhydrous solidus; dehydration reactions in the slab supply volatiles into the wedge, triggering silicic melting. We simulate the migration of melts under buoyancy forces and dynamic pressure gradients. We thereby demonstrate the dynamical controls on the pattern of subduction-zone volcanism (particularly its location, magnitude, and chemical composition). We build on our previous study of the thermal consequences of magma genesis and segregation. We address the question of what controls the location of arc volcanoes themselves [3]. [1] Rees Jones, D. W

  16. Sudbury project (University of Muenster-Ontario Geological Survey): Summary of results - an updated impact model

    Science.gov (United States)

    Avermann, M.; Bischoff, L.; Brockmeyer, P.; Buhl, D.; Deutsch, A.; Dressler, B. O.; Lakomy, R.; Mueller-Mohr, V.; Stoeffler, D.

    1992-01-01

    In 1984 the Ontario Geological Survey initiated a research project on the Sudbury structure (SS) in cooperation with the University of Muenster. The project included field mapping (1984-1989) and petrographic, chemical, and isotope analyses of the major stratigraphic units of the SS. Four diploma theses and four doctoral theses were performed during the project (1984-1992). Specific results of the various investigations are reported. Selected areas of the SS were mapped and sampled: Footwall rocks; Footwall breccia and parts of the sublayer and lower section of the Sudbury Igneous Complex (SIC); Onaping Formation and the upper section of the SIC; and Sudbury breccia and adjacent Footwall rocks along extended profiles up to 55 km from the SIC. All these stratigraphic units of the SS were studied in substantial detail by previous workers. The most important characteristic of the previous research is that it was based either on a volcanic model or on a mixed volcanic-impact model for the origin of the SS. The present project was clearly directed toward a test of the impact origin of the SS without invoking an endogenic component. In general, our results confirm the most widely accepted stratigraphic division of the SS. However, our interpretation of some of the major stratigraphic units is different from most views expressed. The stratigraphy of the SS and its new interpretation is given as a basis for discussion.

  17. Regionalization of climate model results for the North Sea

    Energy Technology Data Exchange (ETDEWEB)

    Kauker, F. [Alfred-Wegener-Institut fuer Polar- und Meeresforschung, Bremerhaven (Germany); Storch, H. von [GKSS-Forschungszentrum Geesthacht GmbH (Germany). Inst. fuer Hydrophysik

    2000-07-01

    A dynamical downscaling for the North Sea is presented. The numerical model used for the study is the coupled ice-ocean model OPYC. In a hindcast of the years 1979 to 1993 it was forced with atmospheric forcing of the ECMWF reanalysis. The models capability in simulating the observed mean state and variability in the North Sea is demonstrated by the hindcast. Two time scale ranges, from weekly to seasonal and the longer-than-seasonal time scales are investigated. Shorter time scales, for storm surges, are not captured by the model formulation. The main modes of variability of sea level, sea-surface circulation, sea-surface temperature, and sea-surface salinity are described and connections to atmospheric phenomena, like the NAO, are discussed. T106 ''time-slice'' simulations with a ''2 x CO{sub 2}'' horizon are used to estimate the effects of a changing climate on the shelf sea ''North Sea''. The ''2 x CO{sub 2}'' changes in the surface forcing are accompanied by changes in the lateral oceanic boundary conditions taken from a global coupled climate model. For ''2 x CO{sub 2}'' the time mean sea level increases up to 25 cm in the German Bight in the winter, where 15 cm are due to the surface forcing and 10 cm due to thermal expansion. This change is compared to the ''natural'' variability as simulated in the ECMWF integration and found to be not outside the range spanned by it. The variability of sea level on the weekly-to-seasonal time-scales is significantly reduced in the scenario integration. The variability on the longer-than-seasonal time-scales in the control and scenario runs is much smaller then in the ECMWF integration. This is traced back to the use of ''time-slice'' experiments. Discriminating between locally forced changes and changes induced at the lateral oceanic boundaries of the model in the circulation and

  18. Modeling of rock friction 1. Experimental results and constitutive equations

    International Nuclear Information System (INIS)

    Dieterich, J.H.

    1979-01-01

    Direct shear experiments on ground surfaces of a granodiorite from Raymond, California, at normal stresses of approx.6 MPa demonstrate that competing time, displacement, and velocity, effects control rock friction. It is proposed that the strength of the population of points of contacts between sliding surfaces determines frictional strength and that the population of contacts changes continuously with displacements. Previous experiments demonstrate that the strength of the contacts increases with the age of the contacts. The present experiments establish that a characteristic displacement, proportional to surface roughness, is required to change the population of contacts. Hence during slip the average age of the points of contact and therefore frictional strength decrease as slip velocity increases. Displacement weakening and consequently the potential for unstable slip occur whenever displacement reduces the average age of the contacts. In addition to this velocity dependency, which arises from displacement dependency and time dependency, the experiments also show a competing but transient increase in friction whenever slip velocity increases. Creep of the sliding surface at stresses below that for steady state slip also observed. Constitutive relationships are developed that permit quantitative simulation of the friction versus displacement data as a function of surface roughness and for different time and velocity histories. Unstable slip in experiments is controlled by these constitutive effects and by the stiffness of the experimental system. It is argued that analogous properties control earthquake instability

  19. Guiding center model to interpret neutral particle analyzer results

    Science.gov (United States)

    Englert, G. W.; Reinmann, J. J.; Lauver, M. R.

    1974-01-01

    The theoretical model is discussed, which accounts for drift and cyclotron components of ion motion in a partially ionized plasma. Density and velocity distributions are systematically precribed. The flux into the neutral particle analyzer (NPA) from this plasma is determined by summing over all charge exchange neutrals in phase space which are directed into apertures. Especially detailed data, obtained by sweeping the line of sight of the apertures across the plasma of the NASA Lewis HIP-1 burnout device, are presented. Selection of randomized cyclotron velocity distributions about mean azimuthal drift yield energy distributions which compared well with experiment. Use of data obtained with a bending magnet on the NPA showed that separation between energy distribution curves of various mass species correlate well with a drift divided by mean cyclotron energy parameter of the theory. Use of the guiding center model in conjunction with NPA scans across the plasma aid in estimates of ion density and E field variation with plasma radius.

  20. Use of results from microscopic methods in optical model calculations

    International Nuclear Information System (INIS)

    Lagrange, C.

    1985-11-01

    A concept of vectorization for coupled-channel programs based upon conventional methods is first presented. This has been implanted in our program for its use on the CRAY-1 computer. In a second part we investigate the capabilities of a semi-microscopic optical model involving fewer adjustable parameters than phenomenological ones. The two main ingredients of our calculations are, for spherical or well-deformed nuclei, the microscopic optical-model calculations of Jeukenne, Lejeune and Mahaux and nuclear densities from Hartree-Fock-Bogoliubov calculations using the density-dependent force D1. For transitional nuclei deformation-dependent nuclear structure wave functions are employed to weigh the scattering potentials for different shapes and channels [fr

  1. 1-g model loading tests: methods and results

    Czech Academy of Sciences Publication Activity Database

    Feda, Jaroslav

    1999-01-01

    Roč. 2, č. 4 (1999), s. 371-381 ISSN 1436-6517. [Int.Conf. on Soil - Structure Interaction in Urban Civ. Engineering. Darmstadt, 08.10.1999-09.10.1999] R&D Projects: GA MŠk OC C7.10 Keywords : shallow foundation * model tests * sandy subsoil * bearing capacity * subsoil failure * volume deformation Subject RIV: JM - Building Engineering

  2. Considerations on Modeling Strategies of the Financial Result

    Directory of Open Access Journals (Sweden)

    Lucian Cernuşca

    2012-12-01

    Full Text Available This study's objective is to highlight some of the strategies to maximize or minimize the accounting result, situated un-der the impulse of bad accounting. Although we assist the manipulation of the accounting result, this procedure is done according to the law, been exploited by some entities in knowledge of the lack of justice and accounting regulations.

  3. The physical model of a terraced plot: first results

    Science.gov (United States)

    Perlotto, Chiara; D'Agostino, Vincenzo; Buzzanca, Giacomo

    2017-04-01

    Terrace building have been expanded in the 19th century because of the increased demographic pressure and the need to crop additional areas at steeper slopes. Terraces are also important to regulate the hydrological behavior of the hillslope. Few studies are available in literature on rainfall-runoff processes and flood risk mitigation in terraced areas. Bench terraces, reducing the terrain slope and the length of the overland flow, quantitatively control the runoff flow velocity, facilitating the drainage and thus leading to a reduction of soil erosion. The study of the hydrologic-hydraulic function of terraced slopes is essential in order to evaluate their possible use to cooperate for flood-risk mitigation also preserving the landscape value. This research aims to better focus the times of the hydrological response, which are determined by a hillslope plot bounded by a dry-stone wall, considering both the overland flow and the groundwater. A physical model, characterized by a quasi-real scale, has been built to reproduce the behavior of a 3% outward sloped terrace at bare soil condition. The model consists of a steel metal box (1 m large, 3.3 m long, 2 m high) containing the hillslope terrain. The terrain is equipped with two piezometers, 9 TDR sensors measuring the volumetric water content, a surface spillway at the head releasing the steady discharge under test, a scale at the wall base to measure the outflowing discharge. The experiments deal with different initial moisture condition (non-saturated and saturated), and discharges of 19.5, 12.0 and 5.0 l/min. Each experiment has been replicated, conducting a total number of 12 tests. The volumetric water content analysis produced by the 9 TDR sensors was able to provide a quite satisfactory representation of the soil moisture during the runs. Then, different lag times at the outlet since the inflow initiation were measured both for runoff and groundwater. Moreover, the time of depletion and the piezometer

  4. DISCRETE DEFORMATION WAVE DYNAMICS IN SHEAR ZONES: PHYSICAL MODELLING RESULTS

    Directory of Open Access Journals (Sweden)

    S. A. Bornyakov

    2016-01-01

    Full Text Available Observations of earthquake migration along active fault zones [Richter, 1958; Mogi, 1968] and related theoretical concepts [Elsasser, 1969] have laid the foundation for studying the problem of slow deformation waves in the lithosphere. Despite the fact that this problem has been under study for several decades and discussed in numerous publications, convincing evidence for the existence of deformation waves is still lacking. One of the causes is that comprehensive field studies to register such waves by special tools and equipment, which require sufficient organizational and technical resources, have not been conducted yet.The authors attempted at finding a solution to this problem by physical simulation of a major shear zone in an elastic-viscous-plastic model of the lithosphere. The experiment setup is shown in Figure 1 (A. The model material and boundary conditions were specified in accordance with the similarity criteria (described in detail in [Sherman, 1984; Sherman et al., 1991; Bornyakov et al., 2014]. The montmorillonite clay-and-water paste was placed evenly on two stamps of the installation and subject to deformation as the active stamp (1 moved relative to the passive stamp (2 at a constant speed. The upper model surface was covered with fine sand in order to get high-contrast photos. Photos of an emerging shear zone were taken every second by a Basler acA2000-50gm digital camera. Figure 1 (B shows an optical image of a fragment of the shear zone. The photos were processed by the digital image correlation method described in [Sutton et al., 2009]. This method estimates the distribution of components of displacement vectors and strain tensors on the model surface and their evolution over time [Panteleev et al., 2014, 2015].Strain fields and displacements recorded in the optical images of the model surface were estimated in a rectangular box (220.00×72.17 mm shown by a dot-and-dash line in Fig. 1, A. To ensure a sufficient level of

  5. Analysis of inelastic neutron scattering results on model compounds ...

    Indian Academy of Sciences (India)

    Vibrational spectroscopy; nitrogenous bases; inelastic neutron scattering. PACS No. ... obtain good quality, high resolution results in this region. Here the .... knowledge of the character of each molecular transition as well as the calculated.

  6. An Outcrop-based Detailed Geological Model to Test Automated Interpretation of Seismic Inversion Results

    NARCIS (Netherlands)

    Feng, R.; Sharma, S.; Luthi, S.M.; Gisolf, A.

    2015-01-01

    Previously, Tetyukhina et al. (2014) developed a geological and petrophysical model based on the Book Cliffs outcrops that contained eight lithotypes. For reservoir modelling purposes, this model is judged to be too coarse because in the same lithotype it contains reservoir and non-reservoir

  7. MCNP Modeling Results for Location of Buried TRU Waste Drums

    International Nuclear Information System (INIS)

    Steinman, D K; Schweitzer, J S

    2006-01-01

    In the 1960's, fifty-five gallon drums of TRU waste were buried in shallow pits on remote U.S. Government facilities such as the Idaho National Engineering Laboratory (now split into the Idaho National Laboratory and the Idaho Completion Project [ICP]). Subsequently, it was decided to remove the drums and the material that was in them from the burial pits and send the material to the Waste Isolation Pilot Plant in New Mexico. Several technologies have been tried to locate the drums non-intrusively with enough precision to minimize the chance for material to be spread into the environment. One of these technologies is the placement of steel probe holes in the pits into which wireline logging probes can be lowered to measure properties and concentrations of material surrounding the probe holes for evidence of TRU material. There is also a concern that large quantities of volatile organic compounds (VOC) are also present that would contaminate the environment during removal. In 2001, the Idaho National Engineering and Environmental Laboratory (INEEL) built two pulsed neutron wireline logging tools to measure TRU and VOC around the probe holes. The tools are the Prompt Fission Neutron (PFN) and the Pulsed Neutron Gamma (PNG), respectively. They were tested experimentally in surrogate test holes in 2003. The work reported here estimates the performance of the tools using Monte-Carlo modelling prior to field deployment. A MCNP model was constructed by INEEL personnel. It was modified by the authors to assess the ability of the tools to predict quantitatively the position and concentration of TRU and VOC materials disposed around the probe holes. The model was used to simulate the tools scanning the probe holes vertically in five centimetre increments. A drum was included in the model that could be placed near the probe hole and at other locations out to forty-five centimetres from the probe-hole in five centimetre increments. Scans were performed with no chlorine in the

  8. Delta-tilde interpretation of standard linear mixed model results

    DEFF Research Database (Denmark)

    Brockhoff, Per Bruun; Amorim, Isabel de Sousa; Kuznetsova, Alexandra

    2016-01-01

    effects relative to the residual error and to choose the proper effect size measure. For multi-attribute bar plots of F-statistics this amounts, in balanced settings, to a simple transformation of the bar heights to get them transformed into depicting what can be seen as approximately the average pairwise...... data set and compared to actual d-prime calculations based on Thurstonian regression modeling through the ordinal package. For more challenging cases we offer a generic "plug-in" implementation of a version of the method as part of the R-package SensMixed. We discuss and clarify the bias mechanisms...

  9. Solar activity variations of ionosonde measurements and modeling results

    Czech Academy of Sciences Publication Activity Database

    Altadill, D.; Arrazola, D.; Blanch, E.; Burešová, Dalia

    2008-01-01

    Roč. 42, č. 4 (2008), s. 610-616 ISSN 0273-1177 R&D Projects: GA AV ČR 1QS300120506 Grant - others:MCYT(ES) REN2003-08376-C02-02; CSIC(XE) 2004CZ0002; AGAUR(XE) 2006BE00112; AF Research Laboratory(XE) FA8718-L-0072 Institutional research plan: CEZ:AV0Z30420517 Keywords : mid-latitude ionosphere * bottomside modeling * ionospheric variability Subject RIV: DG - Athmosphere Sciences, Meteorology Impact factor: 0.860, year: 2008 http://www.sciencedirect.com/science/journal/02731177

  10. NASA Air Force Cost Model (NAFCOM): Capabilities and Results

    Science.gov (United States)

    McAfee, Julie; Culver, George; Naderi, Mahmoud

    2011-01-01

    NAFCOM is a parametric estimating tool for space hardware. Uses cost estimating relationships (CERs) which correlate historical costs to mission characteristics to predict new project costs. It is based on historical NASA and Air Force space projects. It is intended to be used in the very early phases of a development project. NAFCOM can be used at the subsystem or component levels and estimates development and production costs. NAFCOM is applicable to various types of missions (crewed spacecraft, uncrewed spacecraft, and launch vehicles). There are two versions of the model: a government version that is restricted and a contractor releasable version.

  11. The calculation of exchange forces: General results and specific models

    International Nuclear Information System (INIS)

    Scott, T.C.; Babb, J.F.; Dalgarno, A.; Morgan, J.D. III

    1993-01-01

    In order to clarify questions about the calculation of the exchange energy of a homonuclear molecular ion, an analysis is carried out of a model problem consisting of the one-dimensional limit of H 2 + . It is demonstrated that the use of the infinite polarization expansion for the localized wave function in the Holstein--Herring formula yields an approximate exchange energy which at large internuclear distances R has the correct leading behavior to O(e -R ) and is close to but not equal to the exact exchange energy. The extension to the n-dimensional double-well problem is presented

  12. Guiding center model to interpret neutral particle analyzer results

    International Nuclear Information System (INIS)

    Englert, G.W.; Reinmann, J.J.; Lauver, M.R.

    1974-01-01

    The theoretical model is discussed, which accounts for drift and cyclotron components of ion motion in a partially ionized plasma. Density and velocity distributions are systematically prescribed. The flux into the neutron particle analyzer (NPA) from this plasma is determined by summing over all charge exchange neutrals in phase space which are directed into apertures. Especially detailed data, obtained by sweeping the line of sight of the apertures across the plasma of the NASA Lewis HIP-1 burnout device, are presented. Selection of randomized cyclotron velocity distributions about mean azimuthal drift yield energy distributions which compared well with experiment. Use of data obtained with a bending magnet on the NPA showed that separation between energy distribution curves of various mass species correlate well with a drift divided by mean cyclotron energy parameter of the theory. Use of the guiding center model in conjunction with NPA scans across the plasma aid in estimates of ion density and E field variation with plasma radius. (U.S.)

  13. Comparison of numerical and experimental results of the flow in the U9 Kaplan turbine model

    Science.gov (United States)

    Petit, O.; Mulu, B.; Nilsson, H.; Cervantes, M.

    2010-08-01

    The present work compares simulations made using the OpenFOAM CFD code with experimental measurements of the flow in the U9 Kaplan turbine model. Comparisons of the velocity profiles in the spiral casing and in the draft tube are presented. The U9 Kaplan turbine prototype located in Porjus and its model, located in Älvkarleby, Sweden, have curved inlet pipes that lead the flow to the spiral casing. Nowadays, this curved pipe and its effect on the flow in the turbine is not taken into account when numerical simulations are performed at design stage. To study the impact of the inlet pipe curvature on the flow in the turbine, and to get a better overview of the flow of the whole system, measurements were made on the 1:3.1 model of the U9 turbine. Previously published measurements were taken at the inlet of the spiral casing and just before the guide vanes, using the laser Doppler anemometry (LDA) technique. In the draft tube, a number of velocity profiles were measured using the LDA techniques. The present work extends the experimental investigation with a horizontal section at the inlet of the draft tube. The experimental results are used to specify the inlet boundary condition for the numerical simulations in the draft tube, and to validate the computational results in both the spiral casing and the draft tube. The numerical simulations were realized using the standard k-e model and a block-structured hexahedral wall function mesh.

  14. Comparison of numerical and experimental results of the flow in the U9 Kaplan turbine model

    International Nuclear Information System (INIS)

    Petit, O; Nilsson, H; Mulu, B; Cervantes, M

    2010-01-01

    The present work compares simulations made using the OpenFOAM CFD code with experimental measurements of the flow in the U9 Kaplan turbine model. Comparisons of the velocity profiles in the spiral casing and in the draft tube are presented. The U9 Kaplan turbine prototype located in Porjus and its model, located in Alvkarleby, Sweden, have curved inlet pipes that lead the flow to the spiral casing. Nowadays, this curved pipe and its effect on the flow in the turbine is not taken into account when numerical simulations are performed at design stage. To study the impact of the inlet pipe curvature on the flow in the turbine, and to get a better overview of the flow of the whole system, measurements were made on the 1:3.1 model of the U9 turbine. Previously published measurements were taken at the inlet of the spiral casing and just before the guide vanes, using the laser Doppler anemometry (LDA) technique. In the draft tube, a number of velocity profiles were measured using the LDA techniques. The present work extends the experimental investigation with a horizontal section at the inlet of the draft tube. The experimental results are used to specify the inlet boundary condition for the numerical simulations in the draft tube, and to validate the computational results in both the spiral casing and the draft tube. The numerical simulations were realized using the standard k-e model and a block-structured hexahedral wall function mesh.

  15. Comparison of numerical and experimental results of the flow in the U9 Kaplan turbine model

    Energy Technology Data Exchange (ETDEWEB)

    Petit, O; Nilsson, H [Division of Fluid Mechanics, Chalmers University of Technology, Hoersalsvaegen 7A, SE-41296 Goeteborg (Sweden); Mulu, B; Cervantes, M, E-mail: olivierp@chalmers.s [Division of Fluid Mechanics, Luleaa University of Technology, SE-971 87 Luleaa (Sweden)

    2010-08-15

    The present work compares simulations made using the OpenFOAM CFD code with experimental measurements of the flow in the U9 Kaplan turbine model. Comparisons of the velocity profiles in the spiral casing and in the draft tube are presented. The U9 Kaplan turbine prototype located in Porjus and its model, located in Alvkarleby, Sweden, have curved inlet pipes that lead the flow to the spiral casing. Nowadays, this curved pipe and its effect on the flow in the turbine is not taken into account when numerical simulations are performed at design stage. To study the impact of the inlet pipe curvature on the flow in the turbine, and to get a better overview of the flow of the whole system, measurements were made on the 1:3.1 model of the U9 turbine. Previously published measurements were taken at the inlet of the spiral casing and just before the guide vanes, using the laser Doppler anemometry (LDA) technique. In the draft tube, a number of velocity profiles were measured using the LDA techniques. The present work extends the experimental investigation with a horizontal section at the inlet of the draft tube. The experimental results are used to specify the inlet boundary condition for the numerical simulations in the draft tube, and to validate the computational results in both the spiral casing and the draft tube. The numerical simulations were realized using the standard k-e model and a block-structured hexahedral wall function mesh.

  16. A Risk Prediction Model for Sporadic CRC Based on Routine Lab Results.

    Science.gov (United States)

    Boursi, Ben; Mamtani, Ronac; Hwang, Wei-Ting; Haynes, Kevin; Yang, Yu-Xiao

    2016-07-01

    Current risk scores for colorectal cancer (CRC) are based on demographic and behavioral factors and have limited predictive values. To develop a novel risk prediction model for sporadic CRC using clinical and laboratory data in electronic medical records. We conducted a nested case-control study in a UK primary care database. Cases included those with a diagnostic code of CRC, aged 50-85. Each case was matched with four controls using incidence density sampling. CRC predictors were examined using univariate conditional logistic regression. Variables with p value CRC prediction models which included age, sex, height, obesity, ever smoking, alcohol dependence, and previous screening colonoscopy had an AUC of 0.58 (0.57-0.59) with poor goodness of fit. A laboratory-based model including hematocrit, MCV, lymphocytes, and neutrophil-lymphocyte ratio (NLR) had an AUC of 0.76 (0.76-0.77) and a McFadden's R2 of 0.21 with a NRI of 47.6 %. A combined model including sex, hemoglobin, MCV, white blood cells, platelets, NLR, and oral hypoglycemic use had an AUC of 0.80 (0.79-0.81) with a McFadden's R2 of 0.27 and a NRI of 60.7 %. Similar results were shown in an internal validation set. A laboratory-based risk model had good predictive power for sporadic CRC risk.

  17. Model unspecific search in CMS. First results at 13 TeV

    Energy Technology Data Exchange (ETDEWEB)

    Roemer, Jonas; Albert, Andreas; Duchardt, Deborah; Hebbeker, Thomas; Knutzen, Simon; Lieb, Jonas; Meyer, Arnd; Pook, Tobias [III. Physikalisches Institut A, RWTH Aachen University (Germany)

    2016-07-01

    Following an upgrade in center of mass energy from √(s) = 8 TeV to 13 TeV, the LHC delivered first proton-proton collisions at this unprecedented energy in 2015. The CMS experiment recorded data corresponding to an integrated luminosity of 3.7 fb{sup -1}. Since many theoretical models predict signal cross sections to increase strongly with the center of mass energy, the data taken at √(s) = 13 TeV are competitive to the previous data taking period even with a lower recorded integrated luminosity. The Model Unspecific Search in CMS (MUSiC) searches for physics beyond the standard model independent of theoretical models. Using an automatic method, kinematic distributions of the data are compared with the standard model expectation in every final state. Therefore, MUSiC reduces the chance of overlooking new physics, since even distributions not covered by dedicated analyses are investigated. This talk outlines changes to the analysis made necessary by the increased center of mass energy and first results with lepton triggered events.

  18. Experimental results and modeling of a dynamic hohlraum on SATURN

    International Nuclear Information System (INIS)

    Derzon, M.S.; Allshouse, G.O.; Deeney, C.; Leeper, R.J.; Nash, T.J.; Matuska, W.; Peterson, D.L.; MacFarlane, J.J.; Ryutov, D.D.

    1998-06-01

    Experiments were performed at SATURN, a high current z-pinch, to explore the feasibility of creating a hohlraum by imploding a tungsten wire array onto a low-density foam. Emission measurements in the 200--280 eV energy band were consistent with a 110--135 eV Planckian before the target shock heated, or stagnated, on-axis. Peak pinch radiation temperatures of nominally 160 eV were obtained. Measured early time x-ray emission histories and temperature estimates agree well with modeled performance in the 200--280 eV band using a 2D radiation magneto-hydrodynamics code. However, significant differences are observed in comparisons of the x-ray images and 2D simulations

  19. Results of modeling advanced BWR fuel designs using CASMO-4

    International Nuclear Information System (INIS)

    Knott, D.; Edenius, M.

    1996-01-01

    Advanced BWR fuel designs from General Electric, Siemens and ABB-Atom have been analyzed using CASMO-4 and compared against fission rate distributions and control rod worths from MCNP. Included in the analysis were fuel storage rack configurations and proposed mixed oxide (MOX) designs. Results are also presented from several cycles of SIMULATE-3 core follow analysis, using nodal data generated by CASMO-4, for cycles in transition from 8x8 designs to advanced fuel designs. (author)

  20. First results from the International Urban Energy Balance Model Comparison: Model Complexity

    Science.gov (United States)

    Blackett, M.; Grimmond, S.; Best, M.

    2009-04-01

    A great variety of urban energy balance models has been developed. These vary in complexity from simple schemes that represent the city as a slab, through those which model various facets (i.e. road, walls and roof) to more complex urban forms (including street canyons with intersections) and features (such as vegetation cover and anthropogenic heat fluxes). Some schemes also incorporate detailed representations of momentum and energy fluxes distributed throughout various layers of the urban canopy layer. The models each differ in the parameters they require to describe the site and the in demands they make on computational processing power. Many of these models have been evaluated using observational datasets but to date, no controlled comparisons have been conducted. Urban surface energy balance models provide a means to predict the energy exchange processes which influence factors such as urban temperature, humidity, atmospheric stability and winds. These all need to be modelled accurately to capture features such as the urban heat island effect and to provide key information for dispersion and air quality modelling. A comparison of the various models available will assist in improving current and future models and will assist in formulating research priorities for future observational campaigns within urban areas. In this presentation we will summarise the initial results of this international urban energy balance model comparison. In particular, the relative performance of the models involved will be compared based on their degree of complexity. These results will inform us on ways in which we can improve the modelling of air quality within, and climate impacts of, global megacities. The methodology employed in conducting this comparison followed that used in PILPS (the Project for Intercomparison of Land-Surface Parameterization Schemes) which is also endorsed by the GEWEX Global Land Atmosphere System Study (GLASS) panel. In all cases, models were run

  1. Exact results for the O( N ) model with quenched disorder

    Science.gov (United States)

    Delfino, Gesualdo; Lamsen, Noel

    2018-04-01

    We use scale invariant scattering theory to exactly determine the lines of renormalization group fixed points for O( N )-symmetric models with quenched disorder in two dimensions. Random fixed points are characterized by two disorder parameters: a modulus that vanishes when approaching the pure case, and a phase angle. The critical lines fall into three classes depending on the values of the disorder modulus. Besides the class corresponding to the pure case, a second class has maximal value of the disorder modulus and includes Nishimori-like multicritical points as well as zero temperature fixed points. The third class contains critical lines that interpolate, as N varies, between the first two classes. For positive N , it contains a single line of infrared fixed points spanning the values of N from √{2}-1 to 1. The symmetry sector of the energy density operator is superuniversal (i.e. N -independent) along this line. For N = 2 a line of fixed points exists only in the pure case, but accounts also for the Berezinskii-Kosterlitz-Thouless phase observed in presence of disorder.

  2. Modeling Framework and Results to Inform Charging Infrastructure Investments

    Energy Technology Data Exchange (ETDEWEB)

    Melaina, Marc W [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Wood, Eric W [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-09-01

    The plug-in electric vehicle (PEV) market is experiencing rapid growth with dozens of battery electric (BEV) and plug-in hybrid electric (PHEV) models already available and billions of dollars being invested by automotive manufacturers in the PEV space. Electric range is increasing thanks to larger and more advanced batteries and significant infrastructure investments are being made to enable higher power fast charging. Costs are falling and PEVs are becoming more competitive with conventional vehicles. Moreover, new technologies such as connectivity and automation hold the promise of enhancing the value proposition of PEVs. This presentation outlines a suite of projects funded by the U.S. Department of Energy's Vehicle Technology Office to conduct assessments of the economic value and charging infrastructure requirements of the evolving PEV market. Individual assessments include national evaluations of PEV economic value (assuming 73M PEVs on the road in 2035), national analysis of charging infrastructure requirements (with community and corridor level resolution), and case studies of PEV ownership in Columbus, OH and Massachusetts.

  3. The Multipole Plasma Trap-PIC Modeling Results

    Science.gov (United States)

    Hicks, Nathaniel; Bowman, Amanda; Godden, Katarina

    2017-10-01

    A radio-frequency (RF) multipole structure is studied via particle-in-cell computer modeling, to assess the response of quasi-neutral plasma to the imposed RF fields. Several regimes, such as pair plasma, antimatter plasma, and conventional (ion-electron) plasma are considered. In the case of equal charge-to-mass ratio of plasma species, the effects of the multipole field are symmetric between positive and negative particles. In the case of a charge-to-mass disparity, the multipole RF parameters (frequency, voltage, structure size) may be chosen such that the light species (e.g. electrons) is strongly confined, while the heavy species (e.g. positive ions) does not respond to the RF field. In this case, the trapped negative space charge creates a potential well that then traps the positive species. 2D and 3D particle-in-cell simulations of this concept are presented, to assess plasma response and trapping dependences on multipole order, consequences of the formation of an RF plasma sheath, and the effects of an axial magnetic field. The scalings of trapped plasma parameters are explored in each of the mentioned regimes, to guide the design of prospective experiments investigating each. Supported by U.S. NSF/DOE Partnership in Basic Plasma Science and Engineering Grant PHY-1619615.

  4. Stirling cryocooler test results and design model verification

    International Nuclear Information System (INIS)

    Shimko, M.A.; Stacy, W.D.; McCormick, J.A.

    1990-01-01

    This paper reports on progress in developing a long-life Stirling cycle cryocooler for space borne applications. It presents the results from tests on a preliminary breadboard version of the cryocooler used to demonstrate the feasibility of the technology and to validate the regenerator design code used in its development. This machine achieved a cold-end temperature of 65 K while carrying a 1/2 Watt cooling load. The basic machine is a double-acting, flexure-bearing, split Stirling design with linear electromagnetic drives for the expander and compressors. Flat metal diaphragms replace pistons for both sweeping and sealing the machine working volumes. In addition, the double-acting expander couples to a laminar-channel counterflow recuperative heat exchanger for regeneration. A PC compatible design code was developed for this design approach that calculates regenerator loss including heat transfer irreversibilities, pressure drop, and axial conduction in the regenerator walls

  5. Storm-time meridional flows: a comparison of CINDI observations and model results

    Directory of Open Access Journals (Sweden)

    M. Hairston

    2014-06-01

    Full Text Available During a large geomagnetic storm, the electric field from the polar ionosphere can expand far enough to affect the mid-latitude and equatorial electric fields. These changes in the equatorial zonal electric field, called the penetration field, will cause changes in the meridional ion flows that can be observed by radars and spacecraft. In general this E × B ion flow near the equator caused by the penetration field during undershielding conditions will be upward on the dayside and downward on the nightside of the Earth. Previous analysis of the equatorial meridional flows observed by CINDI instrument on the C/NOFS spacecraft during the 26 September 2011 storm showed that all of the response flows on the dayside were excess downward flows instead of the expected upward flows. These observed storm-time responses are compared to a prediction from a physics-based coupled model of thermosphere–ionosphere–inner-magnetosphere in an effort to explain these observations. The model results suggest that the equatorial downward flow could be attributed to a combined effect of the overshielding and disturbance dynamo processes. However, some discrepancy between the model and observation indicates a need for improving our understanding of how sensitive the equatorial electric field is to various model input parameters that describe the magnetosphere–ionosphere coupling processes.

  6. Modeling results for a linear simulator of a divertor

    International Nuclear Information System (INIS)

    Hooper, E.B.; Brown, M.D.; Byers, J.A.; Casper, T.A.; Cohen, B.I.; Cohen, R.H.; Jackson, M.C.; Kaiser, T.B.; Molvik, A.W.; Nevins, W.M.; Nilson, D.G.; Pearlstein, L.D.; Rognlien, T.D.

    1993-01-01

    A divertor simulator, IDEAL, has been proposed by S. Cohen to study the difficult power-handling requirements of the tokamak program in general and the ITER program in particular. Projections of the power density in the ITER divertor reach ∼ 1 Gw/m 2 along the magnetic fieldlines and > 10 MW/m 2 on a surface inclined at a shallow angle to the fieldlines. These power densities are substantially greater than can be handled reliably on the surface, so new techniques are required to reduce the power density to a reasonable level. Although the divertor physics must be demonstrated in tokamaks, a linear device could contribute to the development because of its flexibility, the easy access to the plasma and to tested components, and long pulse operation (essentially cw). However, a decision to build a simulator requires not just the recognition of its programmatic value, but also confidence that it can meet the required parameters at an affordable cost. Accordingly, as reported here, it was decided to examine the physics of the proposed device, including kinetic effects resulting from the intense heating required to reach the plasma parameters, and to conduct an independent cost estimate. The detailed role of the simulator in a divertor program is not explored in this report

  7. Modelling combustion reactions for gas flaring and its resulting emissions

    Directory of Open Access Journals (Sweden)

    O. Saheed Ismail

    2016-07-01

    Full Text Available Flaring of associated petroleum gas is an age long environmental concern which remains unabated. Flaring of gas maybe a very efficient combustion process especially steam/air assisted flare and more economical than utilization in some oil fields. However, it has serious implications for the environment. This study considered different reaction types and operating conditions for gas flaring. Six combustion equations were generated using the mass balance concept with varying air and combustion efficiency. These equations were coded with a computer program using 12 natural gas samples of different chemical composition and origin to predict the pattern of emission species from gas flaring. The effect of key parameters on the emission output is also shown. CO2, CO, NO, NO2 and SO2 are the anticipated non-hydrocarbon emissions of environmental concern. Results show that the quantity and pattern of these chemical species depended on percentage excess/deficiency of stoichiometric air, natural gas type, reaction type, carbon mass content, impurities, combustion efficiency of the flare system etc. These emissions degrade the environment and human life, so knowing the emission types, pattern and flaring conditions that this study predicts is of paramount importance to governments, environmental agencies and the oil and gas industry.

  8. Environment modelling in near Earth space: Preliminary LDEF results

    Science.gov (United States)

    Coombs, C. R.; Atkinson, D. R.; Wagner, J. D.; Crowell, L. B.; Allbrooks, M.; Watts, A. J.

    1992-01-01

    Hypervelocity impacts by space debris cause not only local cratering or penetrations, but also cause large areas of damage in coated, painted or laminated surfaces. Features examined in these analyses display interesting morphological characteristics, commonly exhibiting a concentric ringed appearance. Virtually all features greater than 0.2 mm in diameter possess a spall zone in which all of the paint was removed from the aluminum surface. These spall zones vary in size from approximately 2 - 5 crater diameters. The actual craters in the aluminum substrate vary from central pits without raised rims, to morphologies more typical of craters formed in aluminum under hypervelocity laboratory conditions for the larger features. Most features also possess what is referred to as a 'shock zone' as well. These zones vary in size from approximately 1 - 20 crater diameters. In most cases, only the outer-most layer of paint was affected by this impact related phenomenon. Several impacts possess ridge-like structures encircling the area in which this outer-most paint layer was removed. In many ways, such features resemble the lunar impact basins, but on an extremely reduced scale. Overall, there were no noticeable penetrations, bulges or spallation features on the backside of the tray. On Row 12, approximately 85 degrees from the leading edge (RAM direction), there was approximately one impact per 15 cm(exp 2). On the trailing edge, there was approximately one impact per 72 cm(exp 2). Currently, craters on four aluminum experiment trays from Bay E09, directly on the leading edge are being measured and analyzed. Preliminary results have produced more than 2200 craters on approximately 1500 cm(exp 2) - or approximately 1 impact per 0.7 cm(exp 2).

  9. Velocity-mass correlation of the O-type stars: model results

    International Nuclear Information System (INIS)

    Stone, R.C.

    1982-01-01

    This paper presents new model results describing the evolution of massive close binaries from their initial ZAMS to post-supernova stages. Unlike the previous conservative study by Stone [Astrophys. J. 232, 520 (1979) (Paper II)], these results allow explicitly for mass loss from the binary system occurring during the core hydrogen- and helium-burning stages of the primary binary star as well as during the Roche lobe overflow. Because of uncertainties in these rates, model results are given for several reasonable choices for these rates. All of the models consistently predict an increasing relation between the peculiar space velocities and masses for runaway OB stars which agrees well with the observed correlations discussed in Stone [Astron. J. 86, 544 (1981) (Paper III)] and also predict a lower limit at Mroughly-equal11M/sub sun/ for the masses of runaway stars, in agreement with the observational limit found by A. Blaauw (Bull. Astron. Inst. Neth. 15, 265, 1961), both of which support the binary-supernova scenario described by van den Heuvel and Heise for the origin of runaway stars. These models also predict that the more massive O stars will produce correspondingly more massive compact remnants, and that most binaries experiencing supernova-induced kick velocities of magnitude V/sub k/> or approx. =300 km s -1 will disrupt following the explosions. The best estimate for this velocity as established from pulsar observations is V/sub k/roughly-equal150 km s -1 , in which case probably only 15% if these binaries will be disrupted by the supernova explosions, and therefore, almost all runaway stars should have either neutron star or black hole companions

  10. Reconstructing Holocene climate using a climate model: Model strategy and preliminary results

    Science.gov (United States)

    Haberkorn, K.; Blender, R.; Lunkeit, F.; Fraedrich, K.

    2009-04-01

    An Earth system model of intermediate complexity (Planet Simulator; PlaSim) is used to reconstruct Holocene climate based on proxy data. The Planet Simulator is a user friendly general circulation model (GCM) suitable for palaeoclimate research. Its easy handling and the modular structure allow for fast and problem dependent simulations. The spectral model is based on the moist primitive equations conserving momentum, mass, energy and moisture. Besides the atmospheric part, a mixed layer-ocean with sea ice and a land surface with biosphere are included. The present-day climate of PlaSim, based on an AMIP II control-run (T21/10L resolution), shows reasonable agreement with ERA-40 reanalysis data. Combining PlaSim with a socio-technological model (GLUES; DFG priority project INTERDYNAMIK) provides improved knowledge on the shift from hunting-gathering to agropastoral subsistence societies. This is achieved by a data assimilation approach, incorporating proxy time series into PlaSim to initialize palaeoclimate simulations during the Holocene. For this, the following strategy is applied: The sensitivities of the terrestrial PlaSim climate are determined with respect to sea surface temperature (SST) anomalies. Here, the focus is the impact of regionally varying SST both in the tropics and the Northern Hemisphere mid-latitudes. The inverse of these sensitivities is used to determine the SST conditions necessary for the nudging of land and coastal proxy climates. Preliminary results indicate the potential, the uncertainty and the limitations of the method.

  11. PV Performance Modeling Methods and Practices: Results from the 4th PV Performance Modeling Collaborative Workshop.

    Energy Technology Data Exchange (ETDEWEB)

    Stein, Joshua [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-03-01

    In 2014, the IEA PVPS Task 13 added the PVPMC as a formal activity to its technical work plan for 2014-2017. The goal of this activity is to expand the reach of the PVPMC to a broader international audience and help to reduce PV performance modeling uncertainties worldwide. One of the main deliverables of this activity is to host one or more PVPMC workshops outside the US to foster more international participation within this collaborative group. This report reviews the results of the first in a series of these joint IEA PVPS Task 13/PVPMC workshops. The 4th PV Performance Modeling Collaborative Workshop was held in Cologne, Germany at the headquarters of TÜV Rheinland on October 22-23, 2015.

  12. Local Inflammation in Fracture Hematoma: Results from a Combined Trauma Model in Pigs

    Directory of Open Access Journals (Sweden)

    K. Horst

    2015-01-01

    Full Text Available Background. Previous studies showed significant interaction between the local and systemic inflammatory response after severe trauma in small animal models. The purpose of this study was to establish a new combined trauma model in pigs to investigate fracture-associated local inflammation and gain information about the early inflammatory stages after polytrauma. Material and Methods. Combined trauma consisted of tibial fracture, lung contusion, liver laceration, and controlled hemorrhage. Animals were mechanically ventilated and under ICU-monitoring for 48 h. Blood and fracture hematoma samples were collected during the time course of the study. Local and systemic levels of serum cytokines and diverse alarmins were measured by ELISA kit. Results. A statistical significant difference in the systemic serum values of IL-6 and HMGB1 was observed when compared to the sham. Moreover, there was a statistical significant difference in the serum values of the fracture hematoma of IL-6, IL-8, IL-10, and HMGB1 when compared to the systemic inflammatory response. However a decrease of local proinflammatory concentrations was observed while anti-inflammatory mediators increased. Conclusion. Our data showed a time-dependent activation of the local and systemic inflammatory response. Indeed it is the first study focusing on the local and systemic inflammatory response to multiple-trauma in a large animal model.

  13. RC Beams Strengthened with Mechanically Fastened Composites: Experimental Results and Numerical Modeling

    Directory of Open Access Journals (Sweden)

    Enzo Martinelli

    2014-03-01

    Full Text Available The use of mechanically-fastened fiber-reinforced polymer (MF-FRP systems has recently emerged as a competitive solution for the flexural strengthening of reinforced concrete (RC beams and slabs. An overview of the experimental research has proven the effectiveness and the potentiality of the MF-FRP technique which is particularly suitable for emergency repairs or when the speed of installation and immediacy of use are imperative. A finite-element (FE model has been recently developed by the authors with the aim to simulate the behavior of RC beams strengthened in bending by MF-FRP laminates; such a model has also been validated by using a wide experimental database collected from the literature. By following the previous study, the FE model and the assembled database are considered herein with the aim of better exploring the influence of some specific aspects on the structural response of MF-FRP strengthened members, such as the bearing stress-slip relationship assumed for the FRP-concrete interface, the stress-strain law considered for reinforcing steel rebars and the cracking process in RC members resulting in the well-known tension stiffening effect. The considerations drawn from this study will be useful to researchers for the calibration of criteria and design rules for strengthening RC beams through MF-FRP laminates.

  14. Run-of-River Impoundments Can Remain Unfilled While Transporting Gravel Bedload: Numerical Modeling Results

    Science.gov (United States)

    Pearson, A.; Pizzuto, J. E.

    2015-12-01

    Previous work at run-of-river (ROR) dams in northern Delaware has shown that bedload supplied to ROR impoundments can be transported over the dam when impoundments remain unfilled. Transport is facilitated by high levels of sand in the impoundment that lowers the critical shear stresses for particle entrainment, and an inversely sloping sediment ramp connecting the impoundment bed (where the water depth is typically equal to the dam height) with the top of the dam (Pearson and Pizzuto, in press). We demonstrate with one-dimensional bed material transport modeling that bed material can move through impoundments and that equilibrium transport (i.e., a balance between supply to and export from the impoundment, with a constant bed elevation) is possible even when the bed elevation is below the top of the dam. Based on our field work and previous HEC-RAS modeling, we assess bed material transport capacity at the base of the sediment ramp (and ignore detailed processes carrying sediment up and ramp and over the dam). The hydraulics at the base of the ramp are computed using a weir equation, providing estimates of water depth, velocity, and friction, based on the discharge and sediment grain size distribution of the impoundment. Bedload transport rates are computed using the Wilcock-Crowe equation, and changes in the impoundment's bed elevation are determined by sediment continuity. Our results indicate that impoundments pass the gravel supplied from upstream with deep pools when gravel supply rate is low, gravel grain sizes are relatively small, sand supply is high, and discharge is high. Conversely, impoundments will tend to fill their pools when gravel supply rate is high, gravel grain sizes are relatively large, sand supply is low, and discharge is low. The rate of bedload supplied to an impoundment is the primary control on how fast equilibrium transport is reached, with discharge having almost no influence on the timing of equilibrium.

  15. Expression of glial fibrillar acidic protein in the sensorimotor cortex of the cerebral hemispheres in the modeling of transient ischemia against the background of previous sensitization by brain antigen and immunocorrection

    Directory of Open Access Journals (Sweden)

    L. M. Yaremenko

    2017-12-01

    Full Text Available Aim. In order to analyze the dynamics of expression of glial fibrillar acidic protein in the sensorimotor cortex of the large hemispheres in the simulation of transient ischemia against the background of previous sensitization by brain antigen and immunocorrection. Materials and methods. The study is conducted on 185 male mature white rats from Wistar line weighing 260-290 g, in which the damage of the brain was modulated. The brain for study was taken on the 1st, 3rd, 10th, 30th and 90th days after the start of the experiment. The histological, immunohistochemical, morphometric and statistical methods were used. Results. Observations have shown that sensitization by the brain antigen causes neurodegenerative changes in the sensorimotor cortex and a moderate increase in the number of GFAP+-gliocytes, which is gradually increasing. The discirculatory changes that occurred with PO and BCA against the background of previous sensitization practically do not lead to changes in the number of GFAP+-cells. Against the background of sensitization by brain antigen, brain ischemia leads to an increase in the number of gliocytes that are GFAP labeled. In the affected hemisphere, their number reaches a maximum in the end of the acute period of ischemia, after which it decreases. But even in 3 months after transient vascular lesion, there are almost twice as many as in conditionally intact rats. This can be a factor that will significantly affect the function of brain regions after a vascular accident. The increase in the number of GFAP+-gliocytes in the contralateral hemisphere allows us to speak about a certain systemic response of astrocytic glia after ischemic trauma. An early reaction to increase of the number of labeled astrocytes just a day after ischemic attack suggests that some of this type of gliocytes does not expresses GFAP under normal conditions. The action of Imunofan in MEAs results in a less significant decrease in manifestations of

  16. Demand for seasonal gas storage in northwest Europe until 2030. Simulation results with a dynamic model

    International Nuclear Information System (INIS)

    De Joode, J.; Oezdemir, Oe.

    2010-01-01

    The fact that depletion of indigenous gas production increases gas import dependency is widely known and accepted. However, there is considerable less attention for the implications of indigenous resource depletion for the provision of seasonal flexibility. The traditionally largest source of seasonal flexibility in Europe is indigenous gas production, mainly based in the Netherlands and the United Kingdom. With the depletion of indigenous sources the market increasingly needs to rely on other sources for seasonal flexibility, such as gas storage facilities. We investigate the future need for gas storage as a source for seasonal flexibility provision using a dynamic gas market model (GASTALE) in which different potential sources for seasonal flexibility - gas production, imports via pipeline, LNG imports and storage facilities - compete with each other in a market-based environment. The inclusion of seasonal flexibility properties in a gas market model allows a more complex analysis of seasonal flexibility issues than previously documented in literature. This is demonstrated in an analysis of the future demand for gas storage in northwestern Europe until 2030. Our results indicate that there is substantial need for additional gas storage facilities and thus supports current project proposals for new investment in gas storage facilities. (author)

  17. RHF RELAP5 model and preliminary loss-of-offsite-power simulation results for LEU conversion

    Energy Technology Data Exchange (ETDEWEB)

    Licht, J. R. [Argonne National Laboratory (ANL), Argonne, IL (United States). Nuclear Engineering Div.; Bergeron, A. [Argonne National Laboratory (ANL), Argonne, IL (United States). Nuclear Engineering Div.; Dionne, B. [Argonne National Laboratory (ANL), Argonne, IL (United States). Nuclear Engineering Div.; Thomas, F. [Institut Laue-Langevin (ILL), Grenoble (Switzerland). RHF Reactor Dept.

    2014-08-01

    The purpose of this document is to describe the current state of the RELAP5 model for the Institut Laue-Langevin High Flux Reactor (RHF) located in Grenoble, France, and provide an update to the key information required to complete, for example, simulations for a loss of offsite power (LOOP) accident. A previous status report identified a list of 22 items to be resolved in order to complete the RELAP5 model. Most of these items have been resolved by ANL and the RHF team. Enough information was available to perform preliminary safety analyses and define the key items that are still required. Section 2 of this document describes the RELAP5 model of RHF. The final part of this section briefly summarizes previous model issues and resolutions. Section 3 of this document describes preliminary LOOP simulations for both HEU and LEU fuel at beginning of cycle conditions.

  18. Books average previous decade of economic misery.

    Science.gov (United States)

    Bentley, R Alexander; Acerbi, Alberto; Ormerod, Paul; Lampos, Vasileios

    2014-01-01

    For the 20(th) century since the Depression, we find a strong correlation between a 'literary misery index' derived from English language books and a moving average of the previous decade of the annual U.S. economic misery index, which is the sum of inflation and unemployment rates. We find a peak in the goodness of fit at 11 years for the moving average. The fit between the two misery indices holds when using different techniques to measure the literary misery index, and this fit is significantly better than other possible correlations with different emotion indices. To check the robustness of the results, we also analysed books written in German language and obtained very similar correlations with the German economic misery index. The results suggest that millions of books published every year average the authors' shared economic experiences over the past decade.

  19. Books Average Previous Decade of Economic Misery

    Science.gov (United States)

    Bentley, R. Alexander; Acerbi, Alberto; Ormerod, Paul; Lampos, Vasileios

    2014-01-01

    For the 20th century since the Depression, we find a strong correlation between a ‘literary misery index’ derived from English language books and a moving average of the previous decade of the annual U.S. economic misery index, which is the sum of inflation and unemployment rates. We find a peak in the goodness of fit at 11 years for the moving average. The fit between the two misery indices holds when using different techniques to measure the literary misery index, and this fit is significantly better than other possible correlations with different emotion indices. To check the robustness of the results, we also analysed books written in German language and obtained very similar correlations with the German economic misery index. The results suggest that millions of books published every year average the authors' shared economic experiences over the past decade. PMID:24416159

  20. Uncertainty in parameterisation and model structure affect simulation results in coupled ecohydrological models

    Directory of Open Access Journals (Sweden)

    S. Arnold

    2009-10-01

    Full Text Available In this paper we develop and apply a conceptual ecohydrological model to investigate the effects of model structure and parameter uncertainty on the simulation of vegetation structure and hydrological dynamics. The model is applied for a typical water limited riparian ecosystem along an ephemeral river: the middle section of the Kuiseb River in Namibia. We modelled this system by coupling an ecological model with a conceptual hydrological model. The hydrological model is storage based with stochastical forcing from the flood. The ecosystem is modelled with a population model, and represents three dominating riparian plant populations. In appreciation of uncertainty about population dynamics, we applied three model versions with increasing complexity. Population parameters were found by Latin hypercube sampling of the parameter space and with the constraint that three species should coexist as observed. Two of the three models were able to reproduce the observed coexistence. However, both models relied on different coexistence mechanisms, and reacted differently to change of long term memory in the flood forcing. The coexistence requirement strongly constrained the parameter space for both successful models. Only very few parameter sets (0.5% of 150 000 samples allowed for coexistence in a representative number of repeated simulations (at least 10 out of 100 and the success of the coexistence mechanism was controlled by the combination of population parameters. The ensemble statistics of average values of hydrologic variables like transpiration and depth to ground water were similar for both models, suggesting that they were mainly controlled by the applied hydrological model. The ensemble statistics of the fluctuations of depth to groundwater and transpiration, however, differed significantly, suggesting that they were controlled by the applied ecological model and coexistence mechanisms. Our study emphasizes that uncertainty about ecosystem

  1. Impact of the volume of gaseous phase in closed reactors on ANC results and modelling

    Science.gov (United States)

    Drapeau, Clémentine; Delolme, Cécile; Lassabatere, Laurent; Blanc, Denise

    2016-04-01

    ) and real reactors conditions (semi-closed systems). The solid phases tested are pure phases (calcite, sulfides, etc.) and synthetic assemblages mimicking complex polluted matrices. The modeling clearly shows that the systems are sensitive to the opening to the atmosphere. If the open system and the system with no gas are entirely different, "real" reactors also differ significantly from the other systems. Apparently, the presence of the gaseous phase in reactors greatly impacts pH and element release. This parameter should be accounted for in ANC experimental procedures and modeling. In addition to this numerical study, experimental results, previously obtained for urban polluted sediments, are analyzed in lights of the findings of the numerical study. This step allows us to strengthen conclusions and to pinpoint at the necessity to account for the gaseous phase when performing and modeling ANC experiments.

  2. AN ANIMAL MODEL OF SCHIZOPHRENIA BASED ON CHRONIC LSD ADMINISTRATION: OLD IDEA, NEW RESULTS

    Science.gov (United States)

    Marona-Lewicka, Danuta; Nichols, Charles D.; Nichols, David E.

    2011-01-01

    Many people who take LSD experience a second temporal phase of LSD intoxication that is qualitatively different, and was described by Daniel Freedman as “clearly a paranoid state.” We have previously shown that the discriminative stimulus effects of LSD in rats also occur in two temporal phases, with initial effects mediated by activation of 5-HT2A receptors (LSD30), and the later temporal phase mediated by dopamine D2-like receptors (LSD90). Surprisingly, we have now found that non-competitive NMDA antagonists produced full substitution in LSD90 rats, but only in older animals, whereas in LSD30, or in younger animals, these drugs did not mimic LSD. Chronic administration of low doses of LSD (>3 months, 0.16 mg/kg every other day) induces a behavioral state characterized by hyperactivity and hyperirritability, increased locomotor activity, anhedonia, and impairment in social interaction that persists at the same magnitude for at least three months after cessation of LSD treatment. These behaviors, which closely resemble those associated with psychosis in humans, are not induced by withdrawal from LSD; rather, they are the result of neuroadaptive changes occurring in the brain during the chronic administration of LSD. These persistent behaviors are transiently reversed by haloperidol and olanzapine, but are insensitive to MDL-100907. Gene expression analysis data show that chronic LSD treatment produced significant changes in multiple neurotransmitter system-related genes, including those for serotonin and dopamine. Thus, we propose that chronic treatment of rats with low doses of LSD can serve as a new animal model of psychosis that may mimic the development and progression of schizophrenia, as well as model the established disease better than current acute drug administration models utilizing amphetamine or NMDA antagonists such as PCP. PMID:21352832

  3. An animal model of schizophrenia based on chronic LSD administration: old idea, new results.

    Science.gov (United States)

    Marona-Lewicka, Danuta; Nichols, Charles D; Nichols, David E

    2011-09-01

    Many people who take LSD experience a second temporal phase of LSD intoxication that is qualitatively different, and was described by Daniel Freedman as "clearly a paranoid state." We have previously shown that the discriminative stimulus effects of LSD in rats also occur in two temporal phases, with initial effects mediated by activation of 5-HT(2A) receptors (LSD30), and the later temporal phase mediated by dopamine D2-like receptors (LSD90). Surprisingly, we have now found that non-competitive NMDA antagonists produced full substitution in LSD90 rats, but only in older animals, whereas in LSD30, or in younger animals, these drugs did not mimic LSD. Chronic administration of low doses of LSD (>3 months, 0.16 mg/kg every other day) induces a behavioral state characterized by hyperactivity and hyperirritability, increased locomotor activity, anhedonia, and impairment in social interaction that persists at the same magnitude for at least three months after cessation of LSD treatment. These behaviors, which closely resemble those associated with psychosis in humans, are not induced by withdrawal from LSD; rather, they are the result of neuroadaptive changes occurring in the brain during the chronic administration of LSD. These persistent behaviors are transiently reversed by haloperidol and olanzapine, but are insensitive to MDL-100907. Gene expression analysis data show that chronic LSD treatment produced significant changes in multiple neurotransmitter system-related genes, including those for serotonin and dopamine. Thus, we propose that chronic treatment of rats with low doses of LSD can serve as a new animal model of psychosis that may mimic the development and progression of schizophrenia, as well as model the established disease better than current acute drug administration models utilizing amphetamine or NMDA antagonists such as PCP. Copyright © 2011 Elsevier Ltd. All rights reserved.

  4. Differential fracture healing resulting from fixation stiffness variability. A mouse model

    International Nuclear Information System (INIS)

    Gardner, M.J.; Putnam, S.M.; Wong, A.; Streubel, P.N.; Kotiya, A.; Silva, M.J.

    2011-01-01

    The mechanisms underlying the interaction between the local mechanical environment and fracture healing are not known. We developed a mouse femoral fracture model with implants of different stiffness, and hypothesized that differential fracture healing would result. Femoral shaft fractures were created in 70 mice, and were treated with an intramedullary nail made of either tungsten (Young's modulus=410 GPa) or aluminium (Young's modulus=70 GPa). Mice were then sacrificed at 2 or 5 weeks. Fracture calluses were analyzed using standard microCT, histological, and biomechanical methods. At 2 weeks, callus volume was significantly greater in the aluminium group than in the tungsten group (61.2 vs. 40.5 mm 3 , p=0.016), yet bone volume within the calluses was no different between the groups (13.2 vs. 12.3 mm 3 ). Calluses from the tungsten group were stiffer on mechanical testing (18.7 vs. 9.7 N/mm, p=0.01). The percent cartilage in the callus was 31.6% in the aluminium group and 22.9% in the tungsten group (p=0.40). At 5 weeks, there were no differences between any of the healed femora. In this study, fracture implants of different stiffness led to different fracture healing in this mouse fracture model. Fractures treated with a stiffer implant had more advanced healing at 2 weeks, but still healed by callus formation. Although this concept has been well documented previously, this particular model could be a valuable research tool to study the healing consequences of altered fixation stiffness, which may provide insight into the pathogenesis and ideal treatment of fractures and non-unions. (author)

  5. Constraining performance assessment models with tracer test results: a comparison between two conceptual models

    Science.gov (United States)

    McKenna, Sean A.; Selroos, Jan-Olof

    Tracer tests are conducted to ascertain solute transport parameters of a single rock feature over a 5-m transport pathway. Two different conceptualizations of double-porosity solute transport provide estimates of the tracer breakthrough curves. One of the conceptualizations (single-rate) employs a single effective diffusion coefficient in a matrix with infinite penetration depth. However, the tracer retention between different flow paths can vary as the ratio of flow-wetted surface to flow rate differs between the path lines. The other conceptualization (multirate) employs a continuous distribution of multiple diffusion rate coefficients in a matrix with variable, yet finite, capacity. Application of these two models with the parameters estimated on the tracer test breakthrough curves produces transport results that differ by orders of magnitude in peak concentration and time to peak concentration at the performance assessment (PA) time and length scales (100,000 years and 1,000 m). These differences are examined by calculating the time limits for the diffusive capacity to act as an infinite medium. These limits are compared across both conceptual models and also against characteristic times for diffusion at both the tracer test and PA scales. Additionally, the differences between the models are examined by re-estimating parameters for the multirate model from the traditional double-porosity model results at the PA scale. Results indicate that for each model the amount of the diffusive capacity that acts as an infinite medium over the specified time scale explains the differences between the model results and that tracer tests alone cannot provide reliable estimates of transport parameters for the PA scale. Results of Monte Carlo runs of the transport models with varying travel times and path lengths show consistent results between models and suggest that the variation in flow-wetted surface to flow rate along path lines is insignificant relative to variability in

  6. MSFC Stream Model Preliminary Results: Modeling Recent Leonid and Perseid Encounters

    Science.gov (United States)

    Cooke, William J.; Moser, Danielle E.

    2004-01-01

    The cometary meteoroid ejection model of Jones and Brown (1996b) was used to simulate ejection from comets 55P/Tempel-Tuttle during the last 12 revolutions, and the last 9 apparitions of 109P/Swift-Tuttle. Using cometary ephemerides generated by the Jet Propulsion Laboratory s (JPL) HORIZONS Solar System Data and Ephemeris Computation Service, two independent ejection schemes were simulated. In the first case, ejection was simulated in 1 hour time steps along the comet s orbit while it was within 2.5 AU of the Sun. In the second case, ejection was simulated to occur at the hour the comet reached perihelion. A 4th order variable step-size Runge-Kutta integrator was then used to integrate meteoroid position and velocity forward in time, accounting for the effects of radiation pressure, Poynting-Robertson drag, and the gravitational forces of the planets, which were computed using JPL s DE406 planetary ephemerides. An impact parameter was computed for each particle approaching the Earth to create a flux profile, and the results compared to observations of the 1998 and 1999 Leonid showers, and the 1993 and 2004 Perseids.

  7. Numerical model of the lowermost Mississippi River as an alluvial-bedrock reach: preliminary results

    Science.gov (United States)

    Viparelli, E.; Nittrouer, J. A.; Mohrig, D. C.; Parker, G.

    2012-12-01

    Recent field studies reveal that the river bed of the Lower Mississippi River is characterized by a transition from alluvium (upstream) to bedrock (downstream). In particular, in the downstream 250 km of the river, fields of actively migrating bedforms alternate with deep zones where a consolidated substratum is exposed. Here we present a first version of a one-dimensional numerical model able to capture the alluvial-bedrock transition in the lowermost Mississippi River, defined herein as the 500-km reach between the Old River Control Structure and the Gulf of Mexico. The flow is assumed to be steady, and the cross-section is divided in two regions, the river channel and the floodplain. The streamwise variation of channel and floodplain geometry is described with synthetic relations derived from field observations. Flow resistance in the river channel is computed with the formulation for low-slope, large sand bed rivers due to Wright and Parker, while a Chezy-type formulation is implemented on the floodplain. Sediment is modeled in terms of bed material and wash load. Suspended load is computed with the Wright-Parker formulation. This treatment allows either uniform sediment or a mixture of different grain sizes, and accounts for stratification effects. Bedload transport rates are estimated with the relation for sediment mixtures of Ashida and Michiue. Previous work documents reasonable agreement between these load relations and field measurements. Washload is routed through the system solving the equation of mass conservation of sediment in suspension in the water column. The gradual transition from the alluvial reach to the bedrock reach is modeled in terms of a "mushy" layer of specified thickness overlying the non-erodible substrate. In the case of a fully alluvial reach, the channel bed elevation is above this mushy layer, while in the case of partial alluvial cover of the substratum, the channel bed elevation is within the mushy layer. Variations in base

  8. Metal fires and their implications for advanced reactors. Part 3: Experimental and modeling results

    International Nuclear Information System (INIS)

    Nowlen, Steven Patrick; Figueroa, Victor G.; Olivier, Tara Jean; Hewson, John C.; Blanchat, Thomas K.

    2010-01-01

    This report details the primary results of the Laboratory Directed Research and Development project (LDRD 08-0857) Metal Fires and Their Implications for Advance Reactors. Advanced reactors may employ liquid metal coolants, typically sodium, because of their many desirable qualities. This project addressed some of the significant challenges associated with the use of liquid metal coolants, primary among these being the extremely rapid oxidation (combustion) that occurs at the high operating temperatures in reactors. The project has identified a number of areas for which gaps existed in knowledge pertinent to reactor safety analyses. Experimental and analysis capabilities were developed in these areas to varying degrees. In conjunction with team participation in a DOE gap analysis panel, focus was on the oxidation of spilled sodium on thermally massive surfaces. These are spills onto surfaces that substantially cool the sodium during the oxidation process, and they are relevant because standard risk mitigation procedures seek to move spill environments into this regime through rapid draining of spilled sodium. While the spilled sodium is not quenched, the burning mode is different in that there is a transition to a smoldering mode that has not been comprehensively described previously. Prior work has described spilled sodium as a pool fire, but there is a crucial, experimentally-observed transition to a smoldering mode of oxidation. A series of experimental measurements have comprehensively described the thermal evolution of this type of sodium fire for the first time. A new physics-based model has been developed that also predicts the thermal evolution of this type of sodium fire for the first time. The model introduces smoldering oxidation through porous oxide layers to go beyond traditional pool fire analyses that have been carried out previously in order to predict experimentally observed trends. Combined, these developments add significantly to the safety

  9. Comparison of model results obtained with several European regional air quality models

    NARCIS (Netherlands)

    Hass, H.; Builtjes, P.J.H.; Simpson, D.; Stern, R.

    1997-01-01

    An intercomparison study has been performed with four photo-oxidant dispersion models (EMEP, EURAD, LOTOS and REM3) which are currently capable of performing photo-oxidant formation calculations over larger path of Europe. The models, in principle, were run in the mode in which they are normally

  10. 22 CFR 40.91 - Certain aliens previously removed.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Certain aliens previously removed. 40.91... IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Aliens Previously Removed § 40.91 Certain aliens previously removed. (a) 5-year bar. An alien who has been found inadmissible, whether as a result...

  11. Groundwater travel time uncertainty analysis. Sensitivity of results to model geometry, and correlations and cross correlations among input parameters

    International Nuclear Information System (INIS)

    Clifton, P.M.

    1985-03-01

    This study examines the sensitivity of the travel time distribution predicted by a reference case model to (1) scale of representation of the model parameters, (2) size of the model domain, (3) correlation range of log-transmissivity, and (4) cross correlations between transmissivity and effective thickness. The basis for the reference model is the preliminary stochastic travel time model previously documented by the Basalt Waste Isolation Project. Results of this study show the following. The variability of the predicted travel times can be adequately represented when the ratio between the size of the zones used to represent the model parameters and the log-transmissivity correlation range is less than about one-fifth. The size of the model domain and the types of boundary conditions can have a strong impact on the distribution of travel times. Longer log-transmissivity correlation ranges cause larger variability in the predicted travel times. Positive cross correlation between transmissivity and effective thickness causes a decrease in the travel time variability. These results demonstrate the need for a sound conceptual model prior to conducting a stochastic travel time analysis

  12. Influence of FGR complexity modelling on the practical results in gas pressure calculation of selected fuel elements from Dukovany NPP

    International Nuclear Information System (INIS)

    Lahodova, M.

    2001-01-01

    A modernization fuel system and advanced fuel for operation up to the high burnup are used in present time in Dukovany NPP. Reloading of the cores are evaluated using computer codes for thermomechanical behavior of the most loaded fuel rods. The paper presents results of parametric calculations performed by the NRI Rez integral code PIN, version 2000 (PIN2k) to assess influence of fission gas release modelling complexity on achieved results. The representative Dukovany NPP fuel rod irradiation history data are used and two cases of fuel parameter variables (soft and hard) are chosen for the comparison. Involved FGR models where the GASREL diffusion model developed in the NRI Rez plc and standard Weisman model that is recommended in the previous version of the PIN integral code. FGR calculation by PIN2k with GASREL model represents more realistic results than standard Weisman's model. Results for linear power, fuel centre temperature, FGR and gas pressure versus burnup are given for two fuel rods

  13. Large-Scale Features of Pliocene Climate: Results from the Pliocene Model Intercomparison Project

    Science.gov (United States)

    Haywood, A. M.; Hill, D.J.; Dolan, A. M.; Otto-Bliesner, B. L.; Bragg, F.; Chan, W.-L.; Chandler, M. A.; Contoux, C.; Dowsett, H. J.; Jost, A.; hide

    2013-01-01

    Climate and environments of the mid-Pliocene warm period (3.264 to 3.025 Ma) have been extensively studied.Whilst numerical models have shed light on the nature of climate at the time, uncertainties in their predictions have not been systematically examined. The Pliocene Model Intercomparison Project quantifies uncertainties in model outputs through a coordinated multi-model and multi-mode data intercomparison. Whilst commonalities in model outputs for the Pliocene are clearly evident, we show substantial variation in the sensitivity of models to the implementation of Pliocene boundary conditions. Models appear able to reproduce many regional changes in temperature reconstructed from geological proxies. However, data model comparison highlights that models potentially underestimate polar amplification. To assert this conclusion with greater confidence, limitations in the time-averaged proxy data currently available must be addressed. Furthermore, sensitivity tests exploring the known unknowns in modelling Pliocene climate specifically relevant to the high latitudes are essential (e.g. palaeogeography, gateways, orbital forcing and trace gasses). Estimates of longer-term sensitivity to CO2 (also known as Earth System Sensitivity; ESS), support previous work suggesting that ESS is greater than Climate Sensitivity (CS), and suggest that the ratio of ESS to CS is between 1 and 2, with a "best" estimate of 1.5.

  14. Three-component model of solar wind--interstellar medium interaction: some numerical results

    International Nuclear Information System (INIS)

    Baranov, V.; Ermakov, M.; Lebedev, M.

    1981-01-01

    A three-component (electrons, protons, H atoms) model for the interaction between the local interstellar medium and the solar wind is considered. A numerical analysis has been performed to determine how resonance charge exchange in interstellar H atoms that have penetrated the solar wind would affect the two-shock model developed previously by Baranov et al. In particular, if n/sub Hinfinity//n/sub e/infinity>10 (n/sub Hinfinity/, n/sub e/infinity denote the number density of H atoms and electrons in the local ISM) the inner shock may approach the sun as closely as the outer planetary orbits

  15. Different Mechanisms of Soil Microbial Response to Global Change Result in Different Outcomes in the MIMICS-CN Model

    Science.gov (United States)

    Kyker-Snowman, E.; Wieder, W. R.; Grandy, S.

    2017-12-01

    Microbial-explicit models of soil carbon (C) and nitrogen (N) cycling have improved upon simulations of C and N stocks and flows at site-to-global scales relative to traditional first-order linear models. However, the response of microbial-explicit soil models to global change factors depends upon which parameters and processes in a model are altered by those factors. We used the MIcrobial-MIneral Carbon Stabilization Model with coupled N cycling (MIMICS-CN) to compare modeled responses to changes in temperature and plant inputs at two previously-modeled sites (Harvard Forest and Kellogg Biological Station). We spun the model up to equilibrium, applied each perturbation, and evaluated 15 years of post-perturbation C and N pools and fluxes. To model the effect of increasing temperatures, we independently examined the impact of decreasing microbial C use efficiency (CUE), increasing the rate of microbial turnover, and increasing Michaelis-Menten kinetic rates of litter decomposition, plus several combinations of the three. For plant inputs, we ran simulations with stepwise increases in metabolic litter, structural litter, whole litter (structural and metabolic), or labile soil C. The cumulative change in soil C or N varied in both sign and magnitude across simulations. For example, increasing kinetic rates of litter decomposition resulted in net releases of both C and N from soil pools, while decreasing CUE produced short-term increases in respiration but long-term accumulation of C in litter pools and shifts in soil C:N as microbial demand for C increased and biomass declined. Given that soil N cycling constrains the response of plant productivity to global change and that soils generate a large amount of uncertainty in current earth system models, microbial-explicit models are a critical opportunity to advance the modeled representation of soils. However, microbial-explicit models must be improved by experiments to isolate the physiological and stoichiometric

  16. Cerebrospinal fluid pressures resulting from experimental traumatic spinal cord injuries in a pig model.

    Science.gov (United States)

    Jones, Claire F; Lee, Jae H T; Burstyn, Uri; Okon, Elena B; Kwon, Brian K; Cripton, Peter A

    2013-10-01

    Despite considerable effort over the last four decades, research has failed to translate into consistently effective treatment options for spinal cord injury (SCI). This is partly attributed to differences between the injury response of humans and rodent models. Some of this difference could be because the cerebrospinal fluid (CSF) layer of the human spine is relatively large, while that of the rodents is extremely thin. We sought to characterize the fluid impulse induced in the CSF by experimental SCIs of moderate and high human-like severity, and to compare this with previous studies in which fluid impulse has been associated with neural tissue injury. We used a new in vivo pig model (n = 6 per injury group, mean age 124.5 days, 20.9 kg) incorporating four miniature pressure transducers that were implanted in pairs in the subarachnoid space, cranial, and caudal to the injury at 30 mm and 100 mm. Tissue sparing was assessed with Eriochrome Cyanine and Neutral Red staining. The median peak pressures near the injury were 522.5 and 868.8 mmHg (range 96.7-1430.0) and far from the injury were 7.6 and 36.3 mmHg (range 3.8-83.7), for the moderate and high injury severities, respectively. Pressure impulse (mmHg.ms), apparent wave speed, and apparent attenuation factor were also evaluated. The data indicates that the fluid pressure wave may be sufficient to affect the severity and extent of primary tissue damage close to the injury site. However, the CSF pressure was close to normal physiologic values at 100 mm from the injury. The high injury severity animals had less tissue sparing than the moderate injury severity animals; this difference was statistically significant only within 1.6 mm of the epicenter. These results indicate that future research seeking to elucidate the mechanical origins of primary tissue damage in SCI should consider the effects of CSF. This pig model provides advantages for basic and preclinical SCI research due to its

  17. Underestimation of Severity of Previous Whiplash Injuries

    Science.gov (United States)

    Naqui, SZH; Lovell, SJ; Lovell, ME

    2008-01-01

    INTRODUCTION We noted a report that more significant symptoms may be expressed after second whiplash injuries by a suggested cumulative effect, including degeneration. We wondered if patients were underestimating the severity of their earlier injury. PATIENTS AND METHODS We studied recent medicolegal reports, to assess subjects with a second whiplash injury. They had been asked whether their earlier injury was worse, the same or lesser in severity. RESULTS From the study cohort, 101 patients (87%) felt that they had fully recovered from their first injury and 15 (13%) had not. Seventy-six subjects considered their first injury of lesser severity, 24 worse and 16 the same. Of the 24 that felt the violence of their first accident was worse, only 8 had worse symptoms, and 16 felt their symptoms were mainly the same or less than their symptoms from their second injury. Statistical analysis of the data revealed that the proportion of those claiming a difference who said the previous injury was lesser was 76% (95% CI 66–84%). The observed proportion with a lesser injury was considerably higher than the 50% anticipated. CONCLUSIONS We feel that subjects may underestimate the severity of an earlier injury and associated symptoms. Reasons for this may include secondary gain rather than any proposed cumulative effect. PMID:18201501

  18. Effect of Estimated Daily Global Solar Radiation Data on the Results of Crop Growth Models

    Directory of Open Access Journals (Sweden)

    Herbert Formayer

    2007-10-01

    Full Text Available The results of previous studies have suggested that estimated daily globalradiation (RG values contain an error that could compromise the precision of subsequentcrop model applications. The following study presents a detailed site and spatial analysis ofthe RG error propagation in CERES and WOFOST crop growth models in Central Europeanclimate conditions. The research was conducted i at the eight individual sites in Austria andthe Czech Republic where measured daily RG values were available as a reference, withseven methods for RG estimation being tested, and ii for the agricultural areas of the CzechRepublic using daily data from 52 weather stations, with five RG estimation methods. In thelatter case the RG values estimated from the hours of sunshine using the ångström-Prescottformula were used as the standard method because of the lack of measured RG data. At thesite level we found that even the use of methods based on hours of sunshine, which showedthe lowest bias in RG estimates, led to a significant distortion of the key crop model outputs.When the ångström-Prescott method was used to estimate RG, for example, deviationsgreater than ±10 per cent in winter wheat and spring barley yields were noted in 5 to 6 percent of cases. The precision of the yield estimates and other crop model outputs was lowerwhen RG estimates based on the diurnal temperature range and cloud cover were used (mean bias error 2.0 to 4.1 per cent. The methods for estimating RG from the diurnal temperature range produced a wheat yield bias of more than 25 per cent in 12 to 16 per cent of the seasons. Such uncertainty in the crop model outputs makes the reliability of any seasonal yield forecasts or climate change impact assessments questionable if they are based on this type of data. The spatial assessment of the RG data uncertainty propagation over the winter wheat yields also revealed significant differences within the study area. We

  19. Photovoltaic Grid-Connected Modeling and Characterization Based on Experimental Results

    Science.gov (United States)

    Humada, Ali M.; Hojabri, Mojgan; Sulaiman, Mohd Herwan Bin; Hamada, Hussein M.; Ahmed, Mushtaq N.

    2016-01-01

    A grid-connected photovoltaic (PV) system operates under fluctuated weather condition has been modeled and characterized based on specific test bed. A mathematical model of a small-scale PV system has been developed mainly for residential usage, and the potential results have been simulated. The proposed PV model based on three PV parameters, which are the photocurrent, IL, the reverse diode saturation current, Io, the ideality factor of diode, n. Accuracy of the proposed model and its parameters evaluated based on different benchmarks. The results showed that the proposed model fitting the experimental results with high accuracy compare to the other models, as well as the I-V characteristic curve. The results of this study can be considered valuable in terms of the installation of a grid-connected PV system in fluctuated climatic conditions. PMID:27035575

  20. Photovoltaic Grid-Connected Modeling and Characterization Based on Experimental Results.

    Science.gov (United States)

    Humada, Ali M; Hojabri, Mojgan; Sulaiman, Mohd Herwan Bin; Hamada, Hussein M; Ahmed, Mushtaq N

    2016-01-01

    A grid-connected photovoltaic (PV) system operates under fluctuated weather condition has been modeled and characterized based on specific test bed. A mathematical model of a small-scale PV system has been developed mainly for residential usage, and the potential results have been simulated. The proposed PV model based on three PV parameters, which are the photocurrent, IL, the reverse diode saturation current, Io, the ideality factor of diode, n. Accuracy of the proposed model and its parameters evaluated based on different benchmarks. The results showed that the proposed model fitting the experimental results with high accuracy compare to the other models, as well as the I-V characteristic curve. The results of this study can be considered valuable in terms of the installation of a grid-connected PV system in fluctuated climatic conditions.

  1. [Computer optical topography: a study of the repeatability of the results of human body model examination].

    Science.gov (United States)

    Sarnadskiĭ, V N

    2007-01-01

    The problem of repeatability of the results of examination of a plastic human body model is considered. The model was examined in 7 positions using an optical topograph for kyphosis diagnosis. The examination was performed under television camera monitoring. It was shown that variation of the model position in the camera view affected the repeatability of the results of topographic examination, especially if the model-to-camera distance was changed. A study of the repeatability of the results of optical topographic examination can help to increase the reliability of the topographic method, which is widely used for medical screening of children and adolescents.

  2. A dynamic bivariate Poisson model for analysing and forecasting match results in the English Premier League

    NARCIS (Netherlands)

    Koopman, S.J.; Lit, R.

    2015-01-01

    Summary: We develop a statistical model for the analysis and forecasting of football match results which assumes a bivariate Poisson distribution with intensity coefficients that change stochastically over time. The dynamic model is a novelty in the statistical time series analysis of match results

  3. Seeking for the rational basis of the Median Model: the optimal combination of multi-model ensemble results

    Directory of Open Access Journals (Sweden)

    A. Riccio

    2007-12-01

    Full Text Available In this paper we present an approach for the statistical analysis of multi-model ensemble results. The models considered here are operational long-range transport and dispersion models, also used for the real-time simulation of pollutant dispersion or the accidental release of radioactive nuclides.

    We first introduce the theoretical basis (with its roots sinking into the Bayes theorem and then apply this approach to the analysis of model results obtained during the ETEX-1 exercise. We recover some interesting results, supporting the heuristic approach called "median model", originally introduced in Galmarini et al. (2004a, b.

    This approach also provides a way to systematically reduce (and quantify model uncertainties, thus supporting the decision-making process and/or regulatory-purpose activities in a very effective manner.

  4. Automatic electromagnetic valve for previous vacuum

    International Nuclear Information System (INIS)

    Granados, C. E.; Martin, F.

    1959-01-01

    A valve which permits the maintenance of an installation vacuum when electric current fails is described. It also lets the air in the previous vacuum bomb to prevent the oil ascending in the vacuum tubes. (Author)

  5. Computational Fluid Dynamics Modeling Of Scaled Hanford Double Shell Tank Mixing - CFD Modeling Sensitivity Study Results

    International Nuclear Information System (INIS)

    Jackson, V.L.

    2011-01-01

    The primary purpose of the tank mixing and sampling demonstration program is to mitigate the technical risks associated with the ability of the Hanford tank farm delivery and celtification systems to measure and deliver a uniformly mixed high-level waste (HLW) feed to the Waste Treatment and Immobilization Plant (WTP) Uniform feed to the WTP is a requirement of 24590-WTP-ICD-MG-01-019, ICD-19 - Interface Control Document for Waste Feed, although the exact definition of uniform is evolving in this context. Computational Fluid Dynamics (CFD) modeling has been used to assist in evaluating scaleup issues, study operational parameters, and predict mixing performance at full-scale.

  6. Test results of the SMES model coil. Cool-down and thermal characteristics

    International Nuclear Information System (INIS)

    Hamada, Kazuya; Kato, Takashi; Kawano, Katsumi

    1998-01-01

    A model coil of a superconducting magnetic energy storage (SMES) device, which is a forced-cooled Nb-Ti coil, has been fabricated and a performance test at cryogenic temperatures has been carried out. The SMES model coil is composed of 4 dual pancakes and its total weight is 4.5 t. The applied conductors are cable-in-conduit conductors cooled by supercritical helium (SHe) at 4.5 K and 0.7 MPa. SHe is supplied to the SMES model coil and the structure by a reciprocating bellows pump. The test facility is located at the International Thermonuclear Experimental Reactor (ITER) common test facility, was constructed for the testing of an ITER central solenoid model coil. In the experiments, cool-down was finished within 10 days under controlled temperature differences in the SMES model coil. During cool-down and 4.5 K operation, pressure drop characteristics of the conductor were measured and the friction factor estimated. The pressure drop characteristics of the SMES model coil were in good agreement with those of the previous cable-in-conduit conductor. During static operation without current, the heat load and refrigerator operation conditions were measured. The heat load of the SMES model coil is 7.5 W, which is within the expected value. (author)

  7. Numerical modelling of radon-222 entry into houses: An outline of techniques and results

    DEFF Research Database (Denmark)

    Andersen, C.E.

    2001-01-01

    Numerical modelling is a powerful tool for studies of soil gas and radon-222 entry into houses. It is the purpose of this paper to review some main techniques and results. In the past, modelling has focused on Darcy flow of soil gas (driven by indoor–outdoor pressure differences) and combined...... diffusive and advective transport of radon. Models of different complexity have been used. The simpler ones are finite-difference models with one or two spatial dimensions. The more complex models allow for full three-dimensional and time dependency. Advanced features include: soil heterogeneity, anisotropy......, fractures, moisture, non-uniform soil temperature, non-Darcy flow of gas, and flow caused by changes in the atmospheric pressure. Numerical models can be used to estimate the importance of specific factors for radon entry. Models are also helpful when results obtained in special laboratory or test structure...

  8. Updating the CHAOS series of field models using Swarm data and resulting candidate models for IGRF-12

    DEFF Research Database (Denmark)

    Finlay, Chris; Olsen, Nils; Tøffner-Clausen, Lars

    th order spline representation with knot points spaced at 0.5 year intervals. The resulting field model is able to consistently fit data from six independent low Earth orbit satellites: Oersted, CHAMP, SAC-C and the three Swarm satellites. As an example, we present comparisons of the excellent model...... therefore conclude that Swarm data is suitable for building high-resolution models of the large-scale internal field, and proceed to extract IGRF-12 candidate models for the main field in epochs 2010 and 2015, as well as the predicted linear secular variarion for 2015-2020. The properties of these IGRF...... candidate models are briefly presented....

  9. A regional climate model for northern Europe: model description and results from the downscaling of two GCM control simulations

    Science.gov (United States)

    Rummukainen, M.; Räisänen, J.; Bringfelt, B.; Ullerstig, A.; Omstedt, A.; Willén, U.; Hansson, U.; Jones, C.

    This work presents a regional climate model, the Rossby Centre regional Atmospheric model (RCA1), recently developed from the High Resolution Limited Area Model (HIRLAM). The changes in the HIRLAM parametrizations, necessary for climate-length integrations, are described. A regional Baltic Sea ocean model and a modeling system for the Nordic inland lake systems have been coupled with RCA1. The coupled system has been used to downscale 10-year time slices from two different general circulation model (GCM) simulations to provide high-resolution regional interpretation of large-scale modeling. A selection of the results from the control runs, i.e. the present-day climate simulations, are presented: large-scale free atmospheric fields, the surface temperature and precipitation results and results for the on-line simulated regional ocean and lake surface climates. The regional model modifies the surface climate description compared to the GCM simulations, but it is also substantially affected by the biases in the GCM simulations. The regional model also improves the representation of the regional ocean and the inland lakes, compared to the GCM results.

  10. A regional climate model for northern Europe: model description and results from the downscaling of two GCM control simulations

    Energy Technology Data Exchange (ETDEWEB)

    Rummukainen, M.; Raeisaenen, J.; Bringfelt, B.; Ullerstig, A.; Omstedt, A.; Willen, U.; Hansson, U.; Jones, C. [Rossby Centre, Swedish Meteorological and Hydrological Inst., Norrkoeping (Sweden)

    2001-03-01

    This work presents a regional climate model, the Rossby Centre regional Atmospheric model (RCA1), recently developed from the High Resolution Limited Area Model (HIRLAM). The changes in the HIRLAM parametrizations, necessary for climate-length integrations, are described. A regional Baltic Sea ocean model and a modeling system for the Nordic inland lake systems have been coupled with RCA1. The coupled system has been used to downscale 10-year time slices from two different general circulation model (GCM) simulations to provide high-resolution regional interpretation of large-scale modeling. A selection of the results from the control runs, i.e. the present-day climate simulations, are presented: large-scale free atmospheric fields, the surface temperature and precipitation results and results for the on-line simulated regional ocean and lake surface climates. The regional model modifies the surface climate description compared to the GCM simulations, but it is also substantially affected by the biases in the GCM simulations. The regional model also improves the representation of the regional ocean and the inland lakes, compared to the GCM results. (orig.)

  11. Study on driver model for hybrid truck based on driving simulator experimental results

    Directory of Open Access Journals (Sweden)

    Dam Hoang Phuc

    2018-04-01

    Full Text Available In this paper, a proposed car-following driver model taking into account some features of both the compensatory and anticipatory model representing the human pedal operation has been verified by driving simulator experiments with several real drivers. The comparison between computer simulations performed by determined model parameters with the experimental results confirm the correctness of this mathematical driver model and identified model parameters. Then the driver model is joined to a hybrid vehicle dynamics model and the moderate car following maneuver simulations with various driver parameters are conducted to investigate influences of driver parameters on vehicle dynamics response and fuel economy. Finally, major driver parameters involved in the longitudinal control of drivers are clarified. Keywords: Driver model, Driver-vehicle closed-loop system, Car Following, Driving simulator/hybrid electric vehicle (B1

  12. Oxidation of hazardous waste in supercritical water: A comparison of modeling and experimental results for methanol destruction

    International Nuclear Information System (INIS)

    Butler, P.B.; Bergan, N.E.; Bramlette, T.T.; Pitz, W.J.; Westbrook, C.K.

    1991-01-01

    Recent experiments at Sandia National Laboratories conducted in conjunction with MODEC Corporation have demonstrated successful clean- up of contaminated water in a supercritical water reactor. These experiments targeted wastes of interest to Department of Energy production facilities. In this paper we present modeling and experimental results for a surrogate waste containing 98% water, 2% methanol, and parts per million of chlorinated hydrocarbons and laser dyes. Our initial modeling results consider only methanol and water. Experimental data are available for inlet and outlet conditions and axial temperature profiles along the outside reactor wall. The purpose of our model is to study the chemical and physical processes inside the reactor. We are particularly interested in the parameters that control the location of the reaction zone. The laboratory-scale reactor operates at 25 MPa., between 300 K and 900 K; it is modeled as a plug-flow reactor with a specified temperature profile. We use Chemkin Real-Gas to calculate mixture density, with the Peng-Robinson equation of state. The elementary reaction set for methanol oxidation and reactions of other C 1 and C 2 hydrocarbons is based on previous models for gas-phase kinetics. Results from our calculations show that the methanol is 99.9% destroyed at 1/3 the total reactor length. Although we were not able to measure composition of the fluid inside the experimental reactor, this prediction occurs near the location of the highest reactor temperature. This indicates that the chemical reaction is triggered by thermal effects, not kinetic rates. Results from ideal-gas calculations show nearly identical chemical profiles inside the reactor in dimensionless distance. However, reactor residence times are overpredicted by nearly 150% using an ideal-gas assumption. Our results indicate that this oxidation process can be successfully modeled using gas-phase chemical mechanisms. 23 refs., 8 figs

  13. Influence of Various Irradiance Models and Their Combination on Simulation Results of Photovoltaic Systems

    Directory of Open Access Journals (Sweden)

    Martin Hofmann

    2017-09-01

    Full Text Available We analyze the output of various state-of-the-art irradiance models for photovoltaic systems. The models include two sun position algorithms, three types of input data time series, nine diffuse fraction models and five transposition models (for tilted surfaces, resulting in 270 different model chains for the photovoltaic (PV system simulation. These model chains are applied to 30 locations worldwide and three different module tracking types, totaling in 24,300 simulations. We show that the simulated PV yearly energy output varies between −5% and +8% for fixed mounted PV modules and between −26% and +14% for modules with two-axis tracking. Model quality varies strongly between locations; sun position algorithms have negligible influence on the simulation results; diffuse fraction models add a lot of variability; and transposition models feature the strongest influence on the simulation results. To highlight the importance of irradiance with high temporal resolution, we present an analysis of the influence of input temporal resolution and simulation models on the inverter clipping losses at varying PV system sizing factors for Lindenberg, Germany. Irradiance in one-minute resolution is essential for accurately calculating inverter clipping losses.

  14. Variability in results from negative binomial models for Lyme disease measured at different spatial scales.

    Science.gov (United States)

    Tran, Phoebe; Waller, Lance

    2015-01-01

    Lyme disease has been the subject of many studies due to increasing incidence rates year after year and the severe complications that can arise in later stages of the disease. Negative binomial models have been used to model Lyme disease in the past with some success. However, there has been little focus on the reliability and consistency of these models when they are used to study Lyme disease at multiple spatial scales. This study seeks to explore how sensitive/consistent negative binomial models are when they are used to study Lyme disease at different spatial scales (at the regional and sub-regional levels). The study area includes the thirteen states in the Northeastern United States with the highest Lyme disease incidence during the 2002-2006 period. Lyme disease incidence at county level for the period of 2002-2006 was linked with several previously identified key landscape and climatic variables in a negative binomial regression model for the Northeastern region and two smaller sub-regions (the New England sub-region and the Mid-Atlantic sub-region). This study found that negative binomial models, indeed, were sensitive/inconsistent when used at different spatial scales. We discuss various plausible explanations for such behavior of negative binomial models. Further investigation of the inconsistency and sensitivity of negative binomial models when used at different spatial scales is important for not only future Lyme disease studies and Lyme disease risk assessment/management but any study that requires use of this model type in a spatial context. Copyright © 2014 Elsevier Inc. All rights reserved.

  15. Field studies of the thermal plume from the D. C. Cook submerged discharge with comparisons to hydraulic-model results

    International Nuclear Information System (INIS)

    Frigo, A.A.; Paddock, R.A.; McCown, D.L.

    1975-06-01

    The Donald C. Cook Nuclear Plant at Bridgman, Michigan, uses submerged-diffuser discharges as a means of disposing waste heat into Lake Michigan. Preliminary results of temperature surveys of the thermal plume at the D. C. Cook Plant are presented. Indications are that the spatial extent of the plume at the surface is much smaller than previous results for surface shoreline discharges, particularly in the near and intermediate portions of the plume. Comparisons of limited prototype data with hydraulic (tank)-model predictions indicate that the model predictions for centerline temperature decay at the surface are too high for the initial 200 m from the discharge, but are generally correct beyond this point to the limits of the model. In addition, the hydraulic-model results underestimate the areal extent of the near and intermediate portions of the plume at the surface. Because this is the first report of a new field program, several inadequacies in the field-measurement techniques are noted and discussed. New techniques that have been developed to remedy these deficiencies, and which will be implemented for future field work, are also described. (auth)

  16. Some important results from the air pollution distribution model STACKS (1988-1992)

    International Nuclear Information System (INIS)

    Erbrink, J.J.

    1993-01-01

    Attention is paid to the results of the study on the distribution of air pollutants by high chimney-stacks of electric power plants. An important product of the study is the integrated distribution model STACKS (Short Term Air-pollutant Concentrations Kema modelling System). The improvements and the extensions of STACKS are described in relation to the National Model, which has been used to estimate the environmental effects of individual chimney-stacks. The National Model shows unacceptable variations for high pollutant sources. Based on the results of STACKS revision of the National model has been taken into consideration. By means of the revised National Model a more realistic estimation of the environmental effects of electric power plants can be carried out

  17. 78 FR 36089 - Airworthiness Directives; Hawker Beechcraft Corporation (Type Certificate Previously Held by...

    Science.gov (United States)

    2013-06-17

    ... Corporation (Type Certificate Previously Held by Raytheon Aircraft Company) Model BAe.125 Series 800A... structural damage or lead to divergent flutter, and result in loss of integrity of the wing, loss of control... to divergent flutter, and result in loss of integrity of the wing, loss of control of the airplane...

  18. Planck intermediate results XXIX. All-sky dust modelling with Planck, IRAS, and WISE observations

    DEFF Research Database (Denmark)

    Ade, P. A. R.; Aghanim, N.; Alves, M. I. R.

    2016-01-01

    We present all-sky modelling of the high resolution Planck, IRAS, andWISE infrared (IR) observations using the physical dust model presented by Draine & Li in 2007 (DL, ApJ, 657, 810). We study the performance and results of this model, and discuss implications for future dust modelling....... The present work extends the DL dust modelling carried out on nearby galaxies using Herschel and Spitzer data to Galactic dust emission. We employ the DL dust model to generate maps of the dust mass surface density Sigma(Md), the dust optical extinction A(V), and the starlight intensity heating the bulk...... of the dust, parametrized by U-min. The DL model reproduces the observed spectral energy distribution (SED) satisfactorily over most of the sky, with small deviations in the inner Galactic disk and in low ecliptic latitude areas, presumably due to zodiacal light contamination. In the Andromeda galaxy (M31...

  19. GENERAL APROACH TO MODELING NONLINEAR AMPLITUDE AND FREQUENCY DEPENDENT HYSTERESIS EFFECTS BASED ON EXPERIMENTAL RESULTS

    Directory of Open Access Journals (Sweden)

    Christopher Heine

    2014-08-01

    Full Text Available A detailed description of the rubber parts’ properties is gaining in importance in the current simulation models of multi-body simulation. One application example is a multi-body simulation of the washing machine movement. Inside the washing machine, there are different force transmission elements, which consist completely or partly of rubber. Rubber parts or, generally, elastomers usually have amplitude-dependant and frequency-dependent force transmission properties. Rheological models are used to describe these properties. A method for characterization of the amplitude and frequency dependence of such a rheological model is presented within this paper. Within this method, the used rheological model can be reduced or expanded in order to illustrate various non-linear effects. An original result is given with the automated parameter identification. It is fully implemented in Matlab. Such identified rheological models are intended for subsequent implementation in a multi-body model. This allows a significant enhancement of the overall model quality.

  20. Crustal Structure of the Andean Foreland in Northern Argentina: Results From Data-Integrative Three-Dimensional Density Modeling

    Science.gov (United States)

    Meeßen, C.; Sippel, J.; Scheck-Wenderoth, M.; Heine, C.; Strecker, M. R.

    2018-02-01

    Previous thermomechanical modeling studies indicated that variations in the temperature and strength of the crystalline crust might be responsible for the juxtaposition of domains with thin-skinned and thick-skinned crustal deformation along strike the foreland of the central Andes. However, there is no evidence supporting this hypothesis from data-integrative models. We aim to derive the density structure of the lithosphere by means of integrated 3-D density modeling, in order to provide a new basis for discussions of compositional variations within the crust and for future thermal and rheological modeling studies. Therefore, we utilize available geological and geophysical data to obtain a structural and density model of the uppermost 200 km of the Earth. The derived model is consistent with the observed Bouguer gravity field. Our results indicate that the crystalline crust in northern Argentina can be represented by a lighter upper crust (2,800 kg/m3) and a denser lower crust (3,100 kg/m3). We find new evidence for high bulk crustal densities >3,000 kg/m3 in the northern Pampia terrane. These could originate from subducted Puncoviscana wackes or pelites that ponded to the base of the crystalline crust in the late Proterozoic or indicate increasing bulk content of mafic material. The precise composition of the northern foreland crust, whether mafic or felsic, has significant implications for further thermomechanical models and the rheological behavior of the lithosphere. A detailed sensitivity analysis of the input parameters indicates that the model results are robust with respect to the given uncertainties of the input data.

  1. Linear regression metamodeling as a tool to summarize and present simulation model results.

    Science.gov (United States)

    Jalal, Hawre; Dowd, Bryan; Sainfort, François; Kuntz, Karen M

    2013-10-01

    Modelers lack a tool to systematically and clearly present complex model results, including those from sensitivity analyses. The objective was to propose linear regression metamodeling as a tool to increase transparency of decision analytic models and better communicate their results. We used a simplified cancer cure model to demonstrate our approach. The model computed the lifetime cost and benefit of 3 treatment options for cancer patients. We simulated 10,000 cohorts in a probabilistic sensitivity analysis (PSA) and regressed the model outcomes on the standardized input parameter values in a set of regression analyses. We used the regression coefficients to describe measures of sensitivity analyses, including threshold and parameter sensitivity analyses. We also compared the results of the PSA to deterministic full-factorial and one-factor-at-a-time designs. The regression intercept represented the estimated base-case outcome, and the other coefficients described the relative parameter uncertainty in the model. We defined simple relationships that compute the average and incremental net benefit of each intervention. Metamodeling produced outputs similar to traditional deterministic 1-way or 2-way sensitivity analyses but was more reliable since it used all parameter values. Linear regression metamodeling is a simple, yet powerful, tool that can assist modelers in communicating model characteristics and sensitivity analyses.

  2. The Plumbing of Land Surface Models: Is Poor Performance a Result of Methodology or Data Quality?

    Science.gov (United States)

    Haughton, Ned; Abramowitz, Gab; Pitman, Andy J.; Or, Dani; Best, Martin J.; Johnson, Helen R.; Balsamo, Gianpaolo; Boone, Aaron; Cuntz, Matthais; Decharme, Bertrand; hide

    2016-01-01

    The PALS Land sUrface Model Benchmarking Evaluation pRoject (PLUMBER) illustrated the value of prescribing a priori performance targets in model intercomparisons. It showed that the performance of turbulent energy flux predictions from different land surface models, at a broad range of flux tower sites using common evaluation metrics, was on average worse than relatively simple empirical models. For sensible heat fluxes, all land surface models were outperformed by a linear regression against downward shortwave radiation. For latent heat flux, all land surface models were outperformed by a regression against downward shortwave, surface air temperature and relative humidity. These results are explored here in greater detail and possible causes are investigated. We examine whether particular metrics or sites unduly influence the collated results, whether results change according to time-scale aggregation and whether a lack of energy conservation in fluxtower data gives the empirical models an unfair advantage in the intercomparison. We demonstrate that energy conservation in the observational data is not responsible for these results. We also show that the partitioning between sensible and latent heat fluxes in LSMs, rather than the calculation of available energy, is the cause of the original findings. Finally, we present evidence suggesting that the nature of this partitioning problem is likely shared among all contributing LSMs. While we do not find a single candidate explanation forwhy land surface models perform poorly relative to empirical benchmarks in PLUMBER, we do exclude multiple possible explanations and provide guidance on where future research should focus.

  3. Predicting ecosystem functioning from plant traits: Results from a multi-scale ecophsiological modeling approach

    NARCIS (Netherlands)

    Wijk, van M.T.

    2007-01-01

    Ecosystem functioning is the result of processes working at a hierarchy of scales. The representation of these processes in a model that is mathematically tractable and ecologically meaningful is a big challenge. In this paper I describe an individual based model (PLACO¿PLAnt COmpetition) that

  4. 77 FR 70176 - Previous Participation Certification

    Science.gov (United States)

    2012-11-23

    ... participants' previous participation in government programs and ensure that the past record is acceptable prior... information is designed to be 100 percent automated and digital submission of all data and certifications is... government programs and ensure that the past record is acceptable prior to granting approval to participate...

  5. On the Tengiz petroleum deposit previous study

    International Nuclear Information System (INIS)

    Nysangaliev, A.N.; Kuspangaliev, T.K.

    1997-01-01

    Tengiz petroleum deposit previous study is described. Some consideration about structure of productive formation, specific characteristic properties of petroleum-bearing collectors are presented. Recommendation on their detail study and using of experience on exploration and development of petroleum deposit which have analogy on most important geological and industrial parameters are given. (author)

  6. Subsequent pregnancy outcome after previous foetal death

    NARCIS (Netherlands)

    Nijkamp, J. W.; Korteweg, F. J.; Holm, J. P.; Timmer, A.; Erwich, J. J. H. M.; van Pampus, M. G.

    Objective: A history of foetal death is a risk factor for complications and foetal death in subsequent pregnancies as most previous risk factors remain present and an underlying cause of death may recur. The purpose of this study was to evaluate subsequent pregnancy outcome after foetal death and to

  7. User's guide to Model Viewer, a program for three-dimensional visualization of ground-water model results

    Science.gov (United States)

    Hsieh, Paul A.; Winston, Richard B.

    2002-01-01

    Model Viewer is a computer program that displays the results of three-dimensional groundwater models. Scalar data (such as hydraulic head or solute concentration) may be displayed as a solid or a set of isosurfaces, using a red-to-blue color spectrum to represent a range of scalar values. Vector data (such as velocity or specific discharge) are represented by lines oriented to the vector direction and scaled to the vector magnitude. Model Viewer can also display pathlines, cells or nodes that represent model features such as streams and wells, and auxiliary graphic objects such as grid lines and coordinate axes. Users may crop the model grid in different orientations to examine the interior structure of the data. For transient simulations, Model Viewer can animate the time evolution of the simulated quantities. The current version (1.0) of Model Viewer runs on Microsoft Windows 95, 98, NT and 2000 operating systems, and supports the following models: MODFLOW-2000, MODFLOW-2000 with the Ground-Water Transport Process, MODFLOW-96, MOC3D (Version 3.5), MODPATH, MT3DMS, and SUTRA (Version 2D3D.1). Model Viewer is designed to directly read input and output files from these models, thus minimizing the need for additional postprocessing. This report provides an overview of Model Viewer. Complete instructions on how to use the software are provided in the on-line help pages.

  8. AFSC/RACE/GAP/Laman: Model Results of Aleutian Island POP distributions

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data supporting the "Model Results of Aleutian Island POP distributions" manuscript are distribution and abundance of Pacific ocean perch from RACEBase,...

  9. First results with the general equilibrium model GEM-E3 Switzerland

    International Nuclear Information System (INIS)

    Bahn, O.; Frei, C.

    2000-01-01

    The GEM-E3 model has been implemented and applied for Switzerland. It has been in particular used to assess an ecological tax reform in Switzerland. Results of this analysis are presented here. (author)

  10. Removal of arsenic from wastewaters by cryptocrystalline magnesite: complimenting experimental results with modelling

    CSIR Research Space (South Africa)

    Masindi, Vhahangwele

    2016-02-01

    Full Text Available -1 Journal of Cleaner Production Removal of arsenic from wastewaters by cryptocrystalline magnesite: complimenting experimental results with modelling Vhahangwele Masindi W. Mugera Gitari Keywords: Arsenic Mine leachates Cryptocrystalline...

  11. Experimental and modelling results of a parallel-plate based active magnetic regenerator

    DEFF Research Database (Denmark)

    Tura, A.; Nielsen, Kaspar Kirstein; Rowe, A.

    2012-01-01

    The performance of a permanent magnet magnetic refrigerator (PMMR) using gadolinium parallel plates is described. The configuration and operating parameters are described in detail. Experimental results are compared to simulations using an established twodimensional model of an active magnetic...

  12. Groundwater travel time uncertainty analysis: Sensitivity of results to model geometry, and correlations and cross correlations among input parameters

    International Nuclear Information System (INIS)

    Clifton, P.M.

    1984-12-01

    The deep basalt formations beneath the Hanford Site are being investigated for the Department of Energy (DOE) to assess their suitability as a host medium for a high level nuclear waste repository. Predicted performance of the proposed repository is an important part of the investigation. One of the performance measures being used to gauge the suitability of the host medium is pre-waste-emplacement groundwater travel times to the accessible environment. Many deterministic analyses of groundwater travel times have been completed by Rockwell and other independent organizations. Recently, Rockwell has completed a preliminary stochastic analysis of groundwater travel times. This document presents analyses that show the sensitivity of the results from the previous stochastic travel time study to: (1) scale of representation of model parameters, (2) size of the model domain, (3) correlation range of log-transmissivity, and (4) cross-correlation between transmissivity and effective thickness. 40 refs., 29 figs., 6 tabs

  13. Modeling the radiation transfer of discontinuous canopies: results for gap probability and single-scattering contribution

    Science.gov (United States)

    Zhao, Feng; Zou, Kai; Shang, Hong; Ji, Zheng; Zhao, Huijie; Huang, Wenjiang; Li, Cunjun

    2010-10-01

    In this paper we present an analytical model for the computation of radiation transfer of discontinuous vegetation canopies. Some initial results of gap probability and bidirectional gap probability of discontinuous vegetation canopies, which are important parameters determining the radiative environment of the canopies, are given and compared with a 3- D computer simulation model. In the model, negative exponential attenuation of light within individual plant canopies is assumed. Then the computation of gap probability is resolved by determining the entry points and exiting points of the ray with the individual plants via their equations in space. For the bidirectional gap probability, which determines the single-scattering contribution of the canopy, a gap statistical analysis based model was adopted to correct the dependence of gap probabilities for both solar and viewing directions. The model incorporates the structural characteristics, such as plant sizes, leaf size, row spacing, foliage density, planting density, leaf inclination distribution. Available experimental data are inadequate for a complete validation of the model. So it was evaluated with a three dimensional computer simulation model for 3D vegetative scenes, which shows good agreement between these two models' results. This model should be useful to the quantification of light interception and the modeling of bidirectional reflectance distributions of discontinuous canopies.

  14. Preliminary results on 3D channel modeling: From theory to standardization

    KAUST Repository

    Kammoun, Abla

    2014-06-01

    Three dimensional (3D) beamforming (also elevation beamforming) is now gaining interest among researchers in wireless communication. The reason can be attributed to its potential for enabling a variety of strategies such as sector or user specific elevation beamforming and cell-splitting. Since these techniques cannot be directly supported by current LTE releases, the 3GPP is now working on defining the required technical specifications. In particular, a large effort is currently being made to get accurate 3D channel models that support the elevation dimension. This step is necessary as it will evaluate the potential of 3D and full dimensional (FD) beamforming techniques to benefit from the richness of real channels. This work aims at presenting the on-going 3GPP study item \\'study on 3D-channel model for elevation beamforming and FD-MIMO studies for LTE\\' and positioning it with respect to previous standardization works. © 2014 IEEE.

  15. Preliminary results on 3D channel modeling: From theory to standardization

    KAUST Repository

    Kammoun, Abla; Khanfir, Hajer; Altman, Zwi; Debbah, Mé roú ane; Kamoun, Mohamed Amine

    2014-01-01

    Three dimensional (3D) beamforming (also elevation beamforming) is now gaining interest among researchers in wireless communication. The reason can be attributed to its potential for enabling a variety of strategies such as sector or user specific elevation beamforming and cell-splitting. Since these techniques cannot be directly supported by current LTE releases, the 3GPP is now working on defining the required technical specifications. In particular, a large effort is currently being made to get accurate 3D channel models that support the elevation dimension. This step is necessary as it will evaluate the potential of 3D and full dimensional (FD) beamforming techniques to benefit from the richness of real channels. This work aims at presenting the on-going 3GPP study item 'study on 3D-channel model for elevation beamforming and FD-MIMO studies for LTE' and positioning it with respect to previous standardization works. © 2014 IEEE.

  16. Application of Physics Model in prediction of the Hellas National election results

    Directory of Open Access Journals (Sweden)

    L. Magafas

    2009-01-01

    Full Text Available In this paper we use a new scientific field called “DemoscopoPhysics” based on chaos theory to predict the Hellenic Na-tional election results in the form of time series for Hellenic political parties, New Democracy (ND, Panhellenic Socialistic Movement (PASOK, Hellenic Communistic Party (KKE, Coalition of the Radical Left (SYRIZA and (Popular Orthodox Rally LAOS”. Using the results of our previous article we reconstruct of the corresponding strange attractor for each political party achieved up to a 30 time steps out of sample

  17. Computation and experiment results of the grounding model of Three Gorges Power Plant

    Energy Technology Data Exchange (ETDEWEB)

    Wen Xishan; Zhang Yuanfang; Yu Jianhui; Chen Cixuan [Wuhan University of Hydraulic and Electrical Engineering (China); Qin Liming; Xu Jun; Shu Lianfu [Yangtze River Water Resources Commission, Wuhan (China)

    1999-07-01

    A model for the computation of the grounding parameters of the grids of Three Gorges Power Plant (TGPP) on the Yangtze River is presented in this paper. Using this model computation and analysis of grounding grids is carried out. The results show that reinforcing the grid of the dam is the main body of current dissipation. It must be reliably welded to form a good grounding grid. The experimental results show that the method and program of the computations are correct. (UK)

  18. New Results on Robust Model Predictive Control for Time-Delay Systems with Input Constraints

    Directory of Open Access Journals (Sweden)

    Qing Lu

    2014-01-01

    Full Text Available This paper investigates the problem of model predictive control for a class of nonlinear systems subject to state delays and input constraints. The time-varying delay is considered with both upper and lower bounds. A new model is proposed to approximate the delay. And the uncertainty is polytopic type. For the state-feedback MPC design objective, we formulate an optimization problem. Under model transformation, a new model predictive controller is designed such that the robust asymptotical stability of the closed-loop system can be guaranteed. Finally, the applicability of the presented results are demonstrated by a practical example.

  19. Modelling of tracer-kinetic results using xylene isomerization as an example

    International Nuclear Information System (INIS)

    Bauer, F.J.; Dermietzel, J.; Roesseler, M.; Koch, H.

    1976-01-01

    The analysis of results from differential or/and integral reactor experiments often admits the interpretation of a chemical reaction in several ways. In addition, the use of mathematical methods for the model selection and planning of experiments is rendered more difficult by great confidence intervals of the ascertained model parameters. The application of radioactively labelled molecules results in improving the knowledge of reaction mechanisms as well as the assessment of parameters obtained. This is shown on the basis of modelling the isomerization of xylene. (author)

  20. Modelling lung cancer due to radon and smoking in WISMUT miners: Preliminary results

    International Nuclear Information System (INIS)

    Bijwaard, H.; Dekkers, F.; Van Dillen, T.

    2011-01-01

    A mechanistic two-stage carcinogenesis model has been applied to model lung-cancer mortality in the largest uranium-miner cohort available. Models with and without smoking action both fit the data well. As smoking information is largely missing from the cohort data, a method has been devised to project this information from a case-control study onto the cohort. Model calculations using 256 projections show that the method works well. Preliminary results show that if an explicit smoking action is absent in the model, this is compensated by the values of the baseline parameters. This indicates that in earlier studies performed without smoking information, the results obtained for the radiation parameters are still valid. More importantly, the inclusion of smoking-related parameters shows that these mainly influence the later stages of lung-cancer development. (authors)

  1. Recent results on the spatiotemporal modelling and comparative analysis of Black Death and bubonic plague epidemics

    Science.gov (United States)

    Christakos, G.; Olea, R.A.; Yu, H.-L.

    2007-01-01

    Background: This work demonstrates the importance of spatiotemporal stochastic modelling in constructing maps of major epidemics from fragmentary information, assessing population impacts, searching for possible etiologies, and performing comparative analysis of epidemics. Methods: Based on the theory previously published by the authors and incorporating new knowledge bases, informative maps of the composite space-time distributions were generated for important characteristics of two major epidemics: Black Death (14th century Western Europe) and bubonic plague (19th-20th century Indian subcontinent). Results: The comparative spatiotemporal analysis of the epidemics led to a number of interesting findings: (1) the two epidemics exhibited certain differences in their spatiotemporal characteristics (correlation structures, trends, occurrence patterns and propagation speeds) that need to be explained by means of an interdisciplinary effort; (2) geographical epidemic indicators confirmed in a rigorous quantitative manner the partial findings of isolated reports and time series that Black Death mortality was two orders of magnitude higher than that of bubonic plague; (3) modern bubonic plague is a rural disease hitting harder the small villages in the countryside whereas Black Death was a devastating epidemic that indiscriminately attacked large urban centres and the countryside, and while the epidemic in India lasted uninterruptedly for five decades, in Western Europe it lasted three and a half years; (4) the epidemics had reverse areal extension features in response to annual seasonal variations. Temperature increase at the end of winter led to an expansion of infected geographical area for Black Death and a reduction for bubonic plague, reaching a climax at the end of spring when the infected area in Western Europe was always larger than in India. Conversely, without exception, the infected area during winter was larger for the Indian bubonic plague; (5) during the

  2. Influence of delayed neutron parameter calculation accuracy on results of modeled WWER scram experiments

    International Nuclear Information System (INIS)

    Artemov, V.G.; Gusev, V.I.; Zinatullin, R.E.; Karpov, A.S.

    2007-01-01

    Using modeled WWER cram rod drop experiments, performed at the Rostov NPP, as an example, the influence of delayed neutron parameters on the modeling results was investigated. The delayed neutron parameter values were taken from both domestic and foreign nuclear databases. Numerical modeling was carried out on the basis of SAPFIR 9 5andWWERrogram package. Parameters of delayed neutrons were acquired from ENDF/B-VI and BNAB-78 validated data files. It was demonstrated that using delay fraction data from different databases in reactivity meters led to significantly different reactivity results. Based on the results of numerically modeled experiments, delayed neutron parameters providing the best agreement between calculated and measured data were selected and recommended for use in reactor calculations (Authors)

  3. Planck 2013 results. XI. All-sky model of thermal dust emission

    CERN Document Server

    Abergel, A; Aghanim, N; Alina, D; Alves, M I R; Armitage-Caplan, C; Arnaud, M; Ashdown, M; Atrio-Barandela, F; Aumont, J; Baccigalupi, C; Banday, A J; Barreiro, R B; Bartlett, J G; Battaner, E; Benabed, K; Benoît, A; Benoit-Lévy, A; Bernard, J -P; Bersanelli, M; Bielewicz, P; Bobin, J; Bock, J J; Bonaldi, A; Bond, J R; Borrill, J; Bouchet, F R; Boulanger, F; Bridges, M; Bucher, M; Burigana, C; Butler, R C; Cardoso, J -F; Catalano, A; Chamballu, A; Chary, R -R; Chiang, H C; Chiang, L -Y; Christensen, P R; Church, S; Clemens, M; Clements, D L; Colombi, S; Colombo, L P L; Combet, C; Couchot, F; Coulais, A; Crill, B P; Curto, A; Cuttaia, F; Danese, L; Davies, R D; Davis, R J; de Bernardis, P; de Rosa, A; de Zotti, G; Delabrouille, J; Delouis, J -M; Désert, F -X; Dickinson, C; Diego, J M; Dole, H; Donzelli, S; Doré, O; Douspis, M; Dupac, X; Efstathiou, G; Enßlin, T A; Eriksen, H K; Falgarone, E; Finelli, F; Forni, O; Frailis, M; Fraisse, A A; Franceschi, E; Galeotta, S; Ganga, K; Ghosh, T; Giard, M; Giardino, G; Giraud-Héraud, Y; González-Nuevo, J; Górski, K M; Gratton, S; Gregorio, A; Grenier, I A; Gruppuso, A; Guillet, V; Hansen, F K; Hanson, D; Harrison, D; Helou, G; Henrot-Versillé, S; Hernández-Monteagudo, C; Herranz, D; Hildebrandt, S R; Hivon, E; Hobson, M; Holmes, W A; Hornstrup, A; Hovest, W; Huffenberger, K M; Jaffe, A H; Jaffe, T R; Jewell, J; Joncas, G; Jones, W C; Juvela, M; Keihänen, E; Keskitalo, R; Kisner, T S; Knoche, J; Knox, L; Kunz, M; Kurki-Suonio, H; Lagache, G; Lähteenmäki, A; Lamarre, J -M; Lasenby, A; Laureijs, R J; Lawrence, C R; Leonardi, R; León-Tavares, J; Lesgourgues, J; Levrier, F; Liguori, M; Lilje, P B; Linden-Vørnle, M; López-Caniego, M; Lubin, P M; Macías-Pérez, J F; Maffei, B; Maino, D; Mandolesi, N; Maris, M; Marshall, D J; Martin, P G; Martínez-González, E; Masi, S; Massardi, M; Matarrese, S; Matthai, F; Mazzotta, P; McGehee, P; Melchiorri, A; Mendes, L; Mennella, A; Migliaccio, M; Mitra, S; Miville-Deschênes, M -A; Moneti, A; Montier, L; Morgante, G; Mortlock, D; Munshi, D; Murphy, J A; Naselsky, P; Nati, F; Natoli, P; Netterfield, C B; Nørgaard-Nielsen, H U; Noviello, F; Novikov, D; Novikov, I; Osborne, S; Oxborrow, C A; Paci, F; Pagano, L; Pajot, F; Paladini, R; Paoletti, D; Pasian, F; Patanchon, G; Perdereau, O; Perotto, L; Perrotta, F; Piacentini, F; Piat, M; Pierpaoli, E; Pietrobon, D; Plaszczynski, S; Pointecouteau, E; Polenta, G; Ponthieu, N; Popa, L; Poutanen, T; Pratt, G W; Prézeau, G; Prunet, S; Puget, J -L; Rachen, J P; Reach, W T; Rebolo, R; Reinecke, M; Remazeilles, M; Renault, C; Ricciardi, S; Riller, T; Ristorcelli, I; Rocha, G; Rosset, C; Roudier, G; Rowan-Robinson, M; Rubiño-Martín, J A; Rusholme, B; Sandri, M; Santos, D; Savini, G; Scott, D; Seiffert, M D; Shellard, E P S; Spencer, L D; Starck, J -L; Stolyarov, V; Stompor, R; Sudiwala, R; Sunyaev, R; Sureau, F; Sutton, D; Suur-Uski, A -S; Sygnet, J -F; Tauber, J A; Tavagnacco, D; Terenzi, L; Toffolatti, L; Tomasi, M; Tristram, M; Tucci, M; Tuovinen, J; Türler, M; Umana, G; Valenziano, L; Valiviita, J; Van Tent, B; Vielva, P; Villa, F; Vittorio, N; Wade, L A; Wandelt, B D; Welikala, N; Yvon, D; Zacchei, A; Zonca, A

    2014-01-01

    This paper presents an all-sky model of dust emission from the Planck 857, 545 and 353 GHz, and IRAS 100 micron data. Using a modified black-body fit to the data we present all-sky maps of the dust optical depth, temperature, and spectral index over the 353-3000 GHz range. This model is a tight representation of the data at 5 arcmin. It shows variations of the order of 30 % compared with the widely-used model of Finkbeiner, Davis, and Schlegel. The Planck data allow us to estimate the dust temperature uniformly over the whole sky, providing an improved estimate of the dust optical depth compared to previous all-sky dust model, especially in high-contrast molecular regions. An increase of the dust opacity at 353 GHz, tau_353/N_H, from the diffuse to the denser interstellar medium (ISM) is reported. It is associated with a decrease in the observed dust temperature, T_obs, that could be due at least in part to the increased dust opacity. We also report an excess of dust emission at HI column densities lower than...

  4. Subsequent childbirth after a previous traumatic birth.

    Science.gov (United States)

    Beck, Cheryl Tatano; Watson, Sue

    2010-01-01

    Nine percent of new mothers in the United States who participated in the Listening to Mothers II Postpartum Survey screened positive for meeting the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for posttraumatic stress disorder after childbirth. Women who have had a traumatic birth experience report fewer subsequent children and a longer length of time before their second baby. Childbirth-related posttraumatic stress disorder impacts couples' physical relationship, communication, conflict, emotions, and bonding with their children. The purpose of this study was to describe the meaning of women's experiences of a subsequent childbirth after a previous traumatic birth. Phenomenology was the research design used. An international sample of 35 women participated in this Internet study. Women were asked, "Please describe in as much detail as you can remember your subsequent pregnancy, labor, and delivery following your previous traumatic birth." Colaizzi's phenomenological data analysis approach was used to analyze the stories of the 35 women. Data analysis yielded four themes: (a) riding the turbulent wave of panic during pregnancy; (b) strategizing: attempts to reclaim their body and complete the journey to motherhood; (c) bringing reverence to the birthing process and empowering women; and (d) still elusive: the longed-for healing birth experience. Subsequent childbirth after a previous birth trauma has the potential to either heal or retraumatize women. During pregnancy, women need permission and encouragement to grieve their prior traumatic births to help remove the burden of their invisible pain.

  5. A hierarchy of models for simulating experimental results from a 3D heterogeneous porous medium

    Science.gov (United States)

    Vogler, Daniel; Ostvar, Sassan; Paustian, Rebecca; Wood, Brian D.

    2018-04-01

    In this work we examine the dispersion of conservative tracers (bromide and fluorescein) in an experimentally-constructed three-dimensional dual-porosity porous medium. The medium is highly heterogeneous (σY2 = 5.7), and consists of spherical, low-hydraulic-conductivity inclusions embedded in a high-hydraulic-conductivity matrix. The bimodal medium was saturated with tracers, and then flushed with tracer-free fluid while the effluent breakthrough curves were measured. The focus for this work is to examine a hierarchy of four models (in the absence of adjustable parameters) with decreasing complexity to assess their ability to accurately represent the measured breakthrough curves. The most information-rich model was (1) a direct numerical simulation of the system in which the geometry, boundary and initial conditions, and medium properties were fully independently characterized experimentally with high fidelity. The reduced-information models included; (2) a simplified numerical model identical to the fully-resolved direct numerical simulation (DNS) model, but using a domain that was one-tenth the size; (3) an upscaled mobile-immobile model that allowed for a time-dependent mass-transfer coefficient; and, (4) an upscaled mobile-immobile model that assumed a space-time constant mass-transfer coefficient. The results illustrated that all four models provided accurate representations of the experimental breakthrough curves as measured by global RMS error. The primary component of error induced in the upscaled models appeared to arise from the neglect of convection within the inclusions. We discuss the necessity to assign value (via a utility function or other similar method) to outcomes if one is to further select from among model options. Interestingly, these results suggested that the conventional convection-dispersion equation, when applied in a way that resolves the heterogeneities, yields models with high fidelity without requiring the imposition of a more

  6. Ex-plant consequence assessment for NUREG-1150: models, typical results, uncertainties

    International Nuclear Information System (INIS)

    Sprung, J.L.

    1988-01-01

    The assessment of ex-plant consequences for NUREG-1150 source terms was performed using the MELCOR Accident Consequence Code System (MACCS). This paper briefly discusses the following elements of MACCS consequence calculations: input data, phenomena modeled, computational framework, typical results, controlling phenomena, and uncertainties. Wherever possible, NUREG-1150 results will be used to illustrate the discussion. 28 references

  7. Empirical Results of Modeling EUR/RON Exchange Rate using ARCH, GARCH, EGARCH, TARCH and PARCH models

    Directory of Open Access Journals (Sweden)

    Andreea – Cristina PETRICĂ

    2017-03-01

    Full Text Available The aim of this study consists in examining the changes in the volatility of daily returns of EUR/RON exchange rate using on the one hand symmetric GARCH models (ARCH and GARCH and on the other hand the asymmetric GARCH models (EGARCH, TARCH and PARCH, since the conditional variance is time-varying. The analysis takes into account daily quotations of EUR/RON exchange rate over the period of 04th January 1999 to 13th June 2016. Thus, we are modeling heteroscedasticity by applying different specifications of GARCH models followed by looking for significant parameters and low information criteria (minimum Akaike Information Criterion. All models are estimated using the maximum likelihood method under the assumption of several distributions of the innovation terms such as: Normal (Gaussian distribution, Student’s t distribution, Generalized Error distribution (GED, Student’s with fixed df. Distribution, and GED with fixed parameter distribution. The predominant models turned out to be EGARCH and PARCH models, and the empirical results point out that the best model for estimating daily returns of EUR/RON exchange rate is EGARCH(2,1 with Asymmetric order 2 under the assumption of Student’s t distributed innovation terms. This can be explained by the fact that in case of EGARCH model, the restriction regarding the positivity of the conditional variance is automatically satisfied.

  8. Previous utilization of service does not improve timely booking in ...

    African Journals Online (AJOL)

    Previous utilization of service does not improve timely booking in antenatal care: Cross sectional study ... Journal Home > Vol 24, No 3 (2010) > ... Results: Past experience on antenatal care service utilization did not come out as a predictor for ...

  9. Deriving user-informed climate information from climate model ensemble results

    Science.gov (United States)

    Huebener, Heike; Hoffmann, Peter; Keuler, Klaus; Pfeifer, Susanne; Ramthun, Hans; Spekat, Arne; Steger, Christian; Warrach-Sagi, Kirsten

    2017-07-01

    Communication between providers and users of climate model simulation results still needs to be improved. In the German regional climate modeling project ReKliEs-De a midterm user workshop was conducted to allow the intended users of the project results to assess the preliminary results and to streamline the final project results to their needs. The user feedback highlighted, in particular, the still considerable gap between climate research output and user-tailored input for climate impact research. Two major requests from the user community addressed the selection of sub-ensembles and some condensed, easy to understand information on the strengths and weaknesses of the climate models involved in the project.

  10. Assessing flood risk at the global scale: model setup, results, and sensitivity

    International Nuclear Information System (INIS)

    Ward, Philip J; Jongman, Brenden; Weiland, Frederiek Sperna; Winsemius, Hessel C; Bouwman, Arno; Ligtvoet, Willem; Van Beek, Rens; Bierkens, Marc F P

    2013-01-01

    Globally, economic losses from flooding exceeded $19 billion in 2012, and are rising rapidly. Hence, there is an increasing need for global-scale flood risk assessments, also within the context of integrated global assessments. We have developed and validated a model cascade for producing global flood risk maps, based on numerous flood return-periods. Validation results indicate that the model simulates interannual fluctuations in flood impacts well. The cascade involves: hydrological and hydraulic modelling; extreme value statistics; inundation modelling; flood impact modelling; and estimating annual expected impacts. The initial results estimate global impacts for several indicators, for example annual expected exposed population (169 million); and annual expected exposed GDP ($1383 billion). These results are relatively insensitive to the extreme value distribution employed to estimate low frequency flood volumes. However, they are extremely sensitive to the assumed flood protection standard; developing a database of such standards should be a research priority. Also, results are sensitive to the use of two different climate forcing datasets. The impact model can easily accommodate new, user-defined, impact indicators. We envisage several applications, for example: identifying risk hotspots; calculating macro-scale risk for the insurance industry and large companies; and assessing potential benefits (and costs) of adaptation measures. (letter)

  11. Comparison of the 1981 INEL dispersion data with results from a number of different models

    Energy Technology Data Exchange (ETDEWEB)

    Lewellen, W S; Sykes, R I; Parker, S F

    1985-05-01

    The results from simulations by 12 different dispersion models are compared with observations from an extensive field experiment conducted by the Nuclear Regulatory Commission at the Idaho National Engineering Laboratory in July, 1981. Comparisons were made on the bases of hourly SF/sub 6/ samples taken at the surface, out to approximately 10 km from the 46 m release tower, both during and following 7 different 8-hour releases. Comparisons are also made for total integrated doses collected out to approximately 40 km. Three classes of models are used. Within the limited range appropriate for Class A models this data comparison shows that neither the puff models or the transport and diffusion models agree with the data any better than the simple Gaussian plume models. The puff and transport and diffusion models do show a slight edge in performance in comparison with the total dose over the extended range approximate for class B models. The best model results for the hourly samples show approximately 40% calculated within a factor of two when a 15/sup 0/ uncertainty in plume position is permitted and it is assumed that higher data samples may occur at stations between the actual sample sites. This is increased to 60% for the 12 hour integrated dose and 70% for the total integrated dose when the same performance measure is used. None of the models reproduce the observed patchy dose patterns. This patchiness is consistent with the discussion of the inherent uncertainty associated with time averaged plume observations contained in our companion reports on the scientific critique of available models.

  12. The use of the k - {epsilon} turbulence model within the Rossby Centre regional ocean climate model: parameterization development and results

    Energy Technology Data Exchange (ETDEWEB)

    Markus Meier, H.E. [Swedish Meteorological and Hydrological Inst., Norrkoeping (Sweden). Rossby Centre

    2000-09-01

    As mixing plays a dominant role for the physics of an estuary like the Baltic Sea (seasonal heat storage, mixing in channels, deep water mixing), different mixing parameterizations for use in 3D Baltic Sea models are discussed and compared. For this purpose two different OGCMs of the Baltic Sea are utilized. Within the Swedish regional climate modeling program, SWECLIM, a 3D coupled ice-ocean model for the Baltic Sea has been coupled with an improved version of the two-equation k - {epsilon} turbulence model with corrected dissipation term, flux boundary conditions to include the effect of a turbulence enhanced layer due to breaking surface gravity waves and a parameterization for breaking internal waves. Results of multi-year simulations are compared with observations. The seasonal thermocline is simulated satisfactory and erosion of the halocline is avoided. Unsolved problems are discussed. To replace the controversial equation for dissipation the performance of a hierarchy of k-models has been tested and compared with the k - {epsilon} model. In addition, it is shown that the results of the mixing parameterization depend very much on the choice of the ocean model. Finally, the impact of two mixing parameterizations on Baltic Sea climate is investigated. In this case the sensitivity of mean SST, vertical temperature and salinity profiles, ice season and seasonal cycle of heat fluxes is quite large.

  13. A computer model to forecast wetland vegetation changes resulting from restoration and protection in coastal Louisiana

    Science.gov (United States)

    Visser, Jenneke M.; Duke-Sylvester, Scott M.; Carter, Jacoby; Broussard, Whitney P.

    2013-01-01

    The coastal wetlands of Louisiana are a unique ecosystem that supports a diversity of wildlife as well as a diverse community of commercial interests of both local and national importance. The state of Louisiana has established a 5-year cycle of scientific investigation to provide up-to-date information to guide future legislation and regulation aimed at preserving this critical ecosystem. Here we report on a model that projects changes in plant community distribution and composition in response to environmental conditions. This model is linked to a suite of other models and requires input from those that simulate the hydrology and morphology of coastal Louisiana. Collectively, these models are used to assess how alternative management plans may affect the wetland ecosystem through explicit spatial modeling of the physical and biological processes affected by proposed modifications to the ecosystem. We have also taken the opportunity to advance the state-of-the-art in wetland plant community modeling by using a model that is more species-based in its description of plant communities instead of one based on aggregated community types such as brackish marsh and saline marsh. The resulting model provides an increased level of ecological detail about how wetland communities are expected to respond. In addition, the output from this model provides critical inputs for estimating the effects of management on higher trophic level species though a more complete description of the shifts in habitat.

  14. Soil gas and radon entry into a simple test structure: Comparison of experimental and modelling results

    DEFF Research Database (Denmark)

    Andersen, C.E.; Søgaard-Hansen, J.; Majborn, B.

    1994-01-01

    A radon test structure has been established at a field site at Riso National Laboratory. Measurements have been made of soil gas entry rates, pressure couplings and radon depletion. The experimental results have been compared with results obtained from measured soil parameters and a two......-dimensional steady-state numerical model of Darcy flow and combined diffusive and advective transport of radon. For most probe locations, the calculated values of the pressure couplings and the radon depletion agree well with the measured values, thus verifying important elements of the Darcy flow approximation......, and the ability of the model to treat combined diffusive and advective transport of radon. However, the model gives an underestimation of the soil gas entry rate. Even if it is assumed that the soil has a permeability equal to the highest of the measured values, the model underestimates the soil gas entry rate...

  15. Ecosystem Model Performance at Wetlands: Results from the North American Carbon Program Site Synthesis

    Science.gov (United States)

    Sulman, B. N.; Desai, A. R.; Schroeder, N. M.; NACP Site Synthesis Participants

    2011-12-01

    Northern peatlands contain a significant fraction of the global carbon pool, and their responses to hydrological change are likely to be important factors in future carbon cycle-climate feedbacks. Global-scale carbon cycle modeling studies typically use general ecosystem models with coarse spatial resolution, often without peatland-specific processes. Here, seven ecosystem models were used to simulate CO2 fluxes at three field sites in Canada and the northern United States, including two nutrient-rich fens and one nutrient-poor, sphagnum-dominated bog, from 2002-2006. Flux residuals (simulated - observed) were positively correlated with measured water table for both gross ecosystem productivity (GEP) and ecosystem respiration (ER) at the two fen sites for all models, and were positively correlated with water table at the bog site for the majority of models. Modeled diurnal cycles at fen sites agreed well with eddy covariance measurements overall. Eddy covariance GEP and ER were higher during dry periods than during wet periods, while model results predicted either the opposite relationship or no significant difference. At the bog site, eddy covariance GEP had no significant dependence on water table, while models predicted higher GEP during wet periods. All models significantly over-estimated GEP at the bog site, and all but one over-estimated ER at the bog site. Carbon cycle models in peatland-rich regions could be improved by incorporating better models or measurements of hydrology and by inhibiting GEP and ER rates under saturated conditions. Bogs and fens likely require distinct treatments in ecosystem models due to differences in nutrients, peat properties, and plant communities.

  16. Insight into collision zone dynamics from topography: numerical modelling results and observations

    OpenAIRE

    A. D. Bottrill; J. van Hunen; M. B. Allen

    2012-01-01

    Dynamic models of subduction and continental collision are used to predict dynamic topography changes on the overriding plate. The modelling results show a distinct evolution of topography on the overriding plate, during subduction, continental collision and slab break-off. A prominent topographic feature is a temporary (few Myrs) deepening in the area of the back arc-basin after initial collision. This collisional mantle dynamic basin (CMDB) is caused by slab steepening drawing material away...

  17. Conditional Tests of Factor Augmented Asset Pricing Models with Human Capital and Housing: Some New Results

    OpenAIRE

    Olga Klinkowska

    2009-01-01

    In this paper I develop the asset pricing model in which the wealth portfolio is enriched with human capital and housing capital. These two types of capital account for a significant portion of the total wealth. Additionally I introduce dynamics into the model and represent conditioning information by common factors estimated with dynamic factor methodology. In this way I can use more accurate representative of the unobservable information set of the investors. Obtained results prove that ind...

  18. Research on PCPV for BWR - physical model as design tool - main results

    International Nuclear Information System (INIS)

    Fumagalli, E.; Verdelli, G.

    1975-01-01

    ISMES (Experimental Institute for Models and Structures) is now carrying out a series of tests on physical models as a part of a research programme sponsored by DSR (Studies and Research Direction) of ENEL (Italian State Electricity Board) on behalf of CPN (Nuclear Design and Construction Centre) of ENEL with the aim to experience a 'Thin'-walled PCPV for 'BWR'. The physical model, together with the mathematical model and the rheological model of the materials, is intended as a meaningful design tool. The mathematical model covers the overall structural design phase, (geometries) and the linear behaviour, whereas the physical model, besides of a global information to be compared with the results of the mathematical model, supplies a number of data as the non-linear behaviour up to failure and local conditions (penetration area etc.) are concerned. The aim of the first phase of this research programme is to make a comparison between the calculation and experiment tests as the thicknesses of the wall and the bottom slab are concerned, whereas the second phase of the research deals with the behaviour of the removable lid and its connection with the main structure. To do this, a model in scale 1:10 has been designed which symmetrically reproduces with respect to the equator, the bottom part of the structure. In the bottom slab the penetrations of the prototype design are reproduced, whereas the upper slab is plain. This paper describes the model, and illustrates the main results, underlining the different behaviour of the upper and bottom slabs up to collapse

  19. [DESCRIPTION AND PRESENTATION OF THE RESULTS OF ELECTROENCEPHALOGRAM PROCESSING USING AN INFORMATION MODEL].

    Science.gov (United States)

    Myznikov, I L; Nabokov, N L; Rogovanov, D Yu; Khankevich, Yu R

    2016-01-01

    The paper proposes to apply the informational modeling of correlation matrix developed by I.L. Myznikov in early 1990s in neurophysiological investigations, such as electroencephalogram recording and analysis, coherence description of signals from electrodes on the head surface. The authors demonstrate information models built using the data from studies of inert gas inhalation by healthy human subjects. In the opinion of the authors, information models provide an opportunity to describe physiological processes with a high level of generalization. The procedure of presenting the EEG results holds great promise for the broad application.

  20. The design, results and future development of the National Energy Strategy Environmental Analysis Model (NESEAM)

    International Nuclear Information System (INIS)

    Fisher, R.E.; Boyd, G.A.; Breed, W.S.

    1991-01-01

    The National Energy Strategy Environmental Model (NESEAM) has been developed to project emissions for the National Energy Strategy (NES). Two scenarios were evaluated for the NES, a Current Policy Base Case and a NES Action Case. The results from the NES Actions Case project much lower emissions than the Current Policy Base Case. Future enhancements to NESEAM will focus on fuel cycle analysis, including future technologies and additional pollutants to model. NESEAM's flexibility will allow it to model other future legislative issues. 7 refs., 4 figs., 2 tabs

  1. Results and Error Estimates from GRACE Forward Modeling over Greenland, Canada, and Alaska

    Science.gov (United States)

    Bonin, J. A.; Chambers, D. P.

    2012-12-01

    Forward modeling using a weighted least squares technique allows GRACE information to be projected onto a pre-determined collection of local basins. This decreases the impact of spatial leakage, allowing estimates of mass change to be better localized. The technique is especially valuable where models of current-day mass change are poor, such as over Greenland and Antarctica. However, the accuracy of the forward model technique has not been determined, nor is it known how the distribution of the local basins affects the results. We use a "truth" model composed of hydrology and ice-melt slopes as an example case, to estimate the uncertainties of this forward modeling method and expose those design parameters which may result in an incorrect high-resolution mass distribution. We then apply these optimal parameters in a forward model estimate created from RL05 GRACE data. We compare the resulting mass slopes with the expected systematic errors from the simulation, as well as GIA and basic trend-fitting uncertainties. We also consider whether specific regions (such as Ellesmere Island and Baffin Island) can be estimated reliably using our optimal basin layout.

  2. Exploring the uncertainties of early detection results: model-based interpretation of mayo lung project

    Directory of Open Access Journals (Sweden)

    Berman Barbara

    2011-03-01

    Full Text Available Abstract Background The Mayo Lung Project (MLP, a randomized controlled clinical trial of lung cancer screening conducted between 1971 and 1986 among male smokers aged 45 or above, demonstrated an increase in lung cancer survival since the time of diagnosis, but no reduction in lung cancer mortality. Whether this result necessarily indicates a lack of mortality benefit for screening remains controversial. A number of hypotheses have been proposed to explain the observed outcome, including over-diagnosis, screening sensitivity, and population heterogeneity (initial difference in lung cancer risks between the two trial arms. This study is intended to provide model-based testing for some of these important arguments. Method Using a micro-simulation model, the MISCAN-lung model, we explore the possible influence of screening sensitivity, systematic error, over-diagnosis and population heterogeneity. Results Calibrating screening sensitivity, systematic error, or over-diagnosis does not noticeably improve the fit of the model, whereas calibrating population heterogeneity helps the model predict lung cancer incidence better. Conclusions Our conclusion is that the hypothesized imperfection in screening sensitivity, systematic error, and over-diagnosis do not in themselves explain the observed trial results. Model fit improvement achieved by accounting for population heterogeneity suggests a higher risk of cancer incidence in the intervention group as compared with the control group.

  3. Does inequality erode social trust? Results from multilevel models of US states and counties.

    Science.gov (United States)

    Fairbrother, Malcolm; Martin, Isaac W

    2013-03-01

    Previous research has argued that income inequality reduces people's trust in other people, and that declining social trust in the United States in recent decades has been due to rising levels of income inequality. Using multilevel models fitted to data from the General Social Survey, this paper substantially qualifies these arguments. We show that while people are less trusting in US states with higher income inequality, this association holds only cross-sectionally, not longitudinally; since the 1970s, states experiencing larger increases in inequality have not suffered systematically larger declines in trust. For counties, there is no statistically significant relationship either cross-sectionally or longitudinally. There is therefore only limited empirical support for the argument that inequality influences generalized social trust; and the declining trust of recent decades certainly cannot be attributed to rising inequality. Copyright © 2012 Elsevier Inc. All rights reserved.

  4. Empowerment perceptions of educational managers from previously ...

    African Journals Online (AJOL)

    Erna Kinsey

    by means of statistical methods such as analysis of variance and correlation ... plify a move away from the authoritarian models of decision-making towards .... lists, parents and learners. ... Encouraged to use self-evaluation and reflection.

  5. Implant breast reconstruction after salvage mastectomy in previously irradiated patients.

    Science.gov (United States)

    Persichetti, Paolo; Cagli, Barbara; Simone, Pierfranco; Cogliandro, Annalisa; Fortunato, Lucio; Altomare, Vittorio; Trodella, Lucio

    2009-04-01

    The most common surgical approach in case of local tumor recurrence after quadrantectomy and radiotherapy is salvage mastectomy. Breast reconstruction is the subsequent phase of the treatment and the plastic surgeon has to operate on previously irradiated and manipulated tissues. The medical literature highlights that breast reconstruction with tissue expanders is not a pursuable option, considering previous radiotherapy a contraindication. The purpose of this retrospective study is to evaluate the influence of previous radiotherapy on 2-stage breast reconstruction (tissue expander/implant). Only patients with analogous timing of radiation therapy and the same demolitive and reconstructive procedures were recruited. The results of this study prove that, after salvage mastectomy in previously irradiated patients, implant reconstruction is still possible. Further comparative studies are, of course, advisable to draw any conclusion on the possibility to perform implant reconstruction in previously irradiated patients.

  6. An analytical model for backscattered luminance in fog: comparisons with Monte Carlo computations and experimental results

    International Nuclear Information System (INIS)

    Taillade, Frédéric; Dumont, Eric; Belin, Etienne

    2008-01-01

    We propose an analytical model for backscattered luminance in fog and derive an expression for the visibility signal-to-noise ratio as a function of meteorological visibility distance. The model uses single scattering processes. It is based on the Mie theory and the geometry of the optical device (emitter and receiver). In particular, we present an overlap function and take the phase function of fog into account. The results of the backscattered luminance obtained with our analytical model are compared to simulations made using the Monte Carlo method based on multiple scattering processes. An excellent agreement is found in that the discrepancy between the results is smaller than the Monte Carlo standard uncertainties. If we take no account of the geometry of the optical device, the results of the model-estimated backscattered luminance differ from the simulations by a factor 20. We also conclude that the signal-to-noise ratio computed with the Monte Carlo method and our analytical model is in good agreement with experimental results since the mean difference between the calculations and experimental measurements is smaller than the experimental uncertainty

  7. THE EFFECTS OF COOPERATIVE LEARNING MODEL GROUP INVESTIGATION AND MOTIVATION TOWARD PHYSICS LEARNING RESULTS MAN TANJUNGBALAI

    Directory of Open Access Journals (Sweden)

    Amalia Febri Aristi

    2014-12-01

    Full Text Available This study aimed to determine: (1 Is there a difference in student's learning outcomes with the application of learning models Investigation Group and Direct Instruction teaching model. (2 Is there a difference in students' motivation with the application of learning models Investigation Group and Direct Instruction teaching model, (3 Is there an interaction between learning models Investigation Group and Direct Instruction to improve students' motivation in learning outcomes Physics. This research is a quasi experimental. The study population was a student of class XII Tanjung Balai MAN. Random sample selection is done by randomizing the class. The instrument used consisted of: (1 achievement test (2 students' motivation questionnaire. The tests are used to obtain the data is shaped essay. The data in this study were analyzed using ANOVA analysis of two paths. The results showed that: (1 there were differences in learning outcomes between students who used the physics model of Group Investigation learning compared with students who used the Direct Instruction teaching model. (2 There was a difference in student's learning outcomes that had a low learning motivation and high motivation to learn both in the classroom and in the classroom Investigation Group Direct Instruction. (3 There was interaction between learning models Instruction Direct Group Investigation and motivation to learn in improving learning outcomes Physics.

  8. Comparison of inverse modeling results with measured and interpolated hydraulic head data

    International Nuclear Information System (INIS)

    Jacobson, E.A.

    1986-12-01

    Inverse modeling of aquifers involves identification of effective parameters, such as transmissivities, based on hydraulic head data. The result of inverse modeling is a calibrated ground water flow model that reproduces the measured hydraulic head data as closely as is statistically possible. An inverse method that includes prior information about the parameters (i.e., kriged log transmissivity) was applied to the Avra Valley aquifer of southern Arizona using hydraulic heads obtained in three ways: measured at well locations, estimated at nodes by hand contouring, and estimated at nodes by kriging. Hand contouring yields only estimates of hydraulic head at node points, whereas kriging yields hydraulic head estimates at node points and their corresponding estimation errors. A comparison of the three inverse applications indicates the variations in the ground water flow model caused by the different treatments of the hydraulic head data. Estimates of hydraulic head computed by all three inverse models were more representative of the measured or interpolated hydraulic heads than those computed using the kriged estimates of log transmissivity. The large-scale trends in the estimates of log transmissivity determined by the three inverse models were generally similar except in the southern portion of the study area. The hydraulic head values and gradients produced by the three inverse models were similar in the interior of the study area, while the major differences between the inverse models occurred along the boundaries. 17 refs., 18 figs., 1 tab

  9. Microstructure evolution during homogenization of Al–Mn–Fe–Si alloys: Modeling and experimental results

    International Nuclear Information System (INIS)

    Du, Q.; Poole, W.J.; Wells, M.A.; Parson, N.C.

    2013-01-01

    Microstructure evolution during the homogenization heat treatment of Al–Mn–Fe–Si, or AA3xxx, alloys has been investigated using a combination of modeling and experimental studies. The model is fully coupled to CALculation PHAse Diagram (CALPHAD) software and has explicitly taken into account the two different length scales for diffusion encountered in modeling the homogenization process. The model is able to predict the evolution of all the important microstructural features during homogenization, including the inhomogeneous spatial distribution of dispersoids and alloying elements in solution, the dispersoid number density and the size distribution, and the type and fraction of intergranular constituent particles. Experiments were conducted using four direct chill (DC) cast AA3xxx alloys subjected to various homogenization treatments. The resulting microstructures were then characterized using a range of characterization techniques, including optical and electron microscopy, electron micro probe analysis, field emission gun scanning electron microscopy, and electrical resistivity measurements. The model predictions have been compared with the experimental measurements to validate the model. Further, it has been demonstrated that the validated model is able to predict the effects of alloying elements (e.g. Si and Mn) on microstructure evolution. It is concluded that the model provides a time and cost effective tool in optimizing and designing industrial AA3xxx alloy chemistries and homogenization heat treatments

  10. Results of the first tests of the SIDRA satellite-borne instrument breadboard model

    International Nuclear Information System (INIS)

    Dudnik, O.V.; Kurbatov, E.V.; Avilov, A.M.; Titov, K.G.; Prieto, M; Sanchez, S.; Spassky, A.V.; Sylwester, J.; Gburek, S.; Podgorski, P.

    2013-01-01

    In this work, the results of the calibration of the solid-state detectors and electronic channels of the SIDRA satellite borne energetic charged particle spectrometer-telescope breadboard model are presented. The block schemes and experimental equipment used to conduct the thermal vacuum and electromagnetic compatibility tests of the assemblies and modules of the compact satellite equipment are described. The results of the measured thermal conditions of operation of the signal analog and digital processing critical modules of the SIDRA instrument prototype are discussed. Finally, the levels of conducted interference generated by the instrument model in the primary vehicle-borne power circuits are presented.

  11. Modelled and Observed Diurnal SST Signals: "SSTDV:R.EX.-IM.A.M." Project Preliminary Results

    DEFF Research Database (Denmark)

    Karagali, Ioanna; Høyer, Jacob; LeBorgne, Pierre

    2013-01-01

    This study presents some of the preliminary results from the ESA Support To Science Element (STSE) funded project on the Diurnal Variability of the Sea Surface Temperature, regarding its Regional Extend and Implications in Atmospheric Modelling (SSTDV:R.EX.–IM.A.M.). During this phase of the proj......This study presents some of the preliminary results from the ESA Support To Science Element (STSE) funded project on the Diurnal Variability of the Sea Surface Temperature, regarding its Regional Extend and Implications in Atmospheric Modelling (SSTDV:R.EX.–IM.A.M.). During this phase...

  12. Comparison of Experimental Surface and Flow Field Measurements to Computational Results of the Juncture Flow Model

    Science.gov (United States)

    Roozeboom, Nettie H.; Lee, Henry C.; Simurda, Laura J.; Zilliac, Gregory G.; Pulliam, Thomas H.

    2016-01-01

    Wing-body juncture flow fields on commercial aircraft configurations are challenging to compute accurately. The NASA Advanced Air Vehicle Program's juncture flow committee is designing an experiment to provide data to improve Computational Fluid Dynamics (CFD) modeling in the juncture flow region. Preliminary design of the model was done using CFD, yet CFD tends to over-predict the separation in the juncture flow region. Risk reduction wind tunnel tests were requisitioned by the committee to obtain a better understanding of the flow characteristics of the designed models. NASA Ames Research Center's Fluid Mechanics Lab performed one of the risk reduction tests. The results of one case, accompanied by CFD simulations, are presented in this paper. Experimental results suggest the wall mounted wind tunnel model produces a thicker boundary layer on the fuselage than the CFD predictions, resulting in a larger wing horseshoe vortex suppressing the side of body separation in the juncture flow region. Compared to experimental results, CFD predicts a thinner boundary layer on the fuselage generates a weaker wing horseshoe vortex resulting in a larger side of body separation.

  13. Conversion of IVA Human Computer Model to EVA Use and Evaluation and Comparison of the Result to Existing EVA Models

    Science.gov (United States)

    Hamilton, George S.; Williams, Jermaine C.

    1998-01-01

    This paper describes the methods, rationale, and comparative results of the conversion of an intravehicular (IVA) 3D human computer model (HCM) to extravehicular (EVA) use and compares the converted model to an existing model on another computer platform. The task of accurately modeling a spacesuited human figure in software is daunting: the suit restricts the human's joint range of motion (ROM) and does not have joints collocated with human joints. The modeling of the variety of materials needed to construct a space suit (e. g. metal bearings, rigid fiberglass torso, flexible cloth limbs and rubber coated gloves) attached to a human figure is currently out of reach of desktop computer hardware and software. Therefore a simplified approach was taken. The HCM's body parts were enlarged and the joint ROM was restricted to match the existing spacesuit model. This basic approach could be used to model other restrictive environments in industry such as chemical or fire protective clothing. In summary, the approach provides a moderate fidelity, usable tool which will run on current notebook computers.

  14. Preliminary results of Physiological plant growth modelling for human life support in space

    Science.gov (United States)

    Sasidharan L, Swathy; Dussap, Claude-Gilles; Hezard, Pauline

    2012-07-01

    physiological plant model, in the case of lettuce (since the leaf metabolic model predominates), the developed model was verified with the carbon consumption of plant, as input. The model predicts the biomass production (as output) with respect to the quantum of light absorbed by the plant. The obtained result was found satisfying for the first initiation in the physiological plant modelling.

  15. Robustness of life cycle assessment results : influence of data variation and modelling choices on results for beverage packaging materials

    NARCIS (Netherlands)

    Harst-Wintraecken, van der E.J.M.

    2015-01-01

    Life cycle assessment (LCA) is a well-established method to evaluate the potential environmental impacts of product and service systems throughout their life cycles. However, it can happen that LCAs for the same product have different and even conflicting outcomes. LCA results need to be robust

  16. Downscaling Ocean Conditions: Initial Results using a Quasigeostrophic and Realistic Ocean Model

    Science.gov (United States)

    Katavouta, Anna; Thompson, Keith

    2014-05-01

    Previous theoretical work (Henshaw et al, 2003) has shown that the small-scale modes of variability of solutions of the unforced, incompressible Navier-Stokes equation, and Burgers' equation, can be reconstructed with surprisingly high accuracy from the time history of a few of the large-scale modes. Motivated by this theoretical work we first describe a straightforward method for assimilating information on the large scales in order to recover the small scale oceanic variability. The method is based on nudging in specific wavebands and frequencies and is similar to the so-called spectral nudging method that has been used successfully for atmospheric downscaling with limited area models (e.g. von Storch et al., 2000). The validity of the method is tested using a quasigestrophic model configured to simulate a double ocean gyre separated by an unstable mid-ocean jet. It is shown that important features of the ocean circulation including the position of the meandering mid-ocean jet and associated pinch-off eddies can indeed be recovered from the time history of a small number of large-scales modes. The benefit of assimilating additional time series of observations from a limited number of locations, that alone are too sparse to significantly improve the recovery of the small scales using traditional assimilation techniques, is also demonstrated using several twin experiments. The final part of the study outlines the application of the approach using a realistic high resolution (1/36 degree) model, based on the NEMO (Nucleus for European Modelling of the Ocean) modeling framework, configured for the Scotian Shelf of the east coast of Canada. The large scale conditions used in this application are obtained from the HYCOM (HYbrid Coordinate Ocean Model) + NCODA (Navy Coupled Ocean Data Assimilation) global 1/12 degree analysis product. Henshaw, W., Kreiss, H.-O., Ystrom, J., 2003. Numerical experiments on the interaction between the larger- and the small-scale motion of

  17. 77 FR 33622 - Airworthiness Directives; Alpha Aviation Concept Limited (Type Certificate Previously Held by...

    Science.gov (United States)

    2012-06-07

    ... Airworthiness Directives; Alpha Aviation Concept Limited (Type Certificate Previously Held by Alpha Aviation... Aviation Concept Limited Model R2160 Airplanes. This AD results from mandatory continuing airworthiness... condition on an aviation product. The MCAI describes the unsafe condition as oil lines fitted to affected...

  18. Reasoning with Previous Decisions: Beyond the Doctrine of Precedent

    DEFF Research Database (Denmark)

    Komárek, Jan

    2013-01-01

    in different jurisdictions use previous judicial decisions in their argument, we need to move beyond the concept of precedent to a wider notion, which would embrace practices and theories in legal systems outside the Common law tradition. This article presents the concept of ‘reasoning with previous decisions...... law method’, but they are no less rational and intellectually sophisticated. The reason for the rather conceited attitude of some comparatists is in the dominance of the common law paradigm of precedent and the accompanying ‘case law method’. If we want to understand how courts and lawyers......’ as such an alternative and develops its basic models. The article first points out several shortcomings inherent in limiting the inquiry into reasoning with previous decisions by the common law paradigm (1). On the basis of numerous examples provided in section (1), I will present two basic models of reasoning...

  19. Results of a modeling workshop concerning preservation and protection of wetlands in North Dakota

    Science.gov (United States)

    Andrews, Austin K.; Auble, Gregor T.; Ellison, Richard A.; Hamilton, David B.; Roelle, James E.

    1981-01-01

    consideration. The modeling process is used to promote communication, identify pertinent issues, identify key data gaps and uncertainties, direct research efforts to fill those gaps, and explore the possible consequences of various management alternatives. The workshop, which was facilitated by the AEA Group of the U.S. Fish and Wildlife Service (FWS), was attended by approximately 25 invited participants representing a variety of interests concerned with the wetlands protection issue in North Dakota. During the week workshop participants conceptualized and constructed a computerized simulation model incorporating many of the hydrologic, agricultural, and wildlife aspects of the wetlands issue. During the process of constructing this model and examining its behavior, participants identified several interesting alternative strategies that may prove useful in an overall wetland protection program, along with a variety of constraints associated with each. Perhaps the most interesting of these alternatives revolve around the idea that there may be a variety of cases in which water can be retained on the land, with concommitant benefits both for wildlife and flood control, without detriment to agricultural productivity. Examples of this kind of activity include flooding of previously drained Type I wetlands in summer fallow areas, installation of smaller drains in Type I and III wetlands to reduce the rate at which water runs off in the spring, and use of strategically located gates in drainage channels associated with the state highway system to slow runoff and create wetland habitat. Several other alternatives discussed at the workshop are related to the notion of using available, uncommitted water supplied to enhance or create wetlands. Several cases were cited in which more certain water supplies would be useful in increasing waterfowl production or reducing disease problems, especially in dry years. Water for such purposes might come from a variety of current of proposed water

  20.  Functional Results-Oriented Healthcare Leadership: A Novel Leadership Model

    Directory of Open Access Journals (Sweden)

    Salem Said Al-Touby

    2012-03-01

    Full Text Available  This article modifies the traditional functional leadership model to accommodate contemporary needs in healthcare leadership based on two findings. First, the article argues that it is important that the ideal healthcare leadership emphasizes the outcomes of the patient care more than processes and structures used to deliver such care; and secondly, that the leadership must strive to attain effectiveness of their care provision and not merely targeting the attractive option of efficient operations. Based on these premises, the paper reviews the traditional Functional Leadership Model and the three elements that define the type of leadership an organization has namely, the tasks, the individuals, and the team. The article argues that concentrating on any one of these elements is not ideal and proposes adding a new element to the model to construct a novel Functional Result-Oriented healthcare leadership model. The recommended Functional-Results Oriented leadership model embosses the results element on top of the other three elements so that every effort on healthcare leadership is directed towards attaining excellent patient outcomes.

  1. Computations for the 1:5 model of the THTR pressure vessel compared with experimental results

    International Nuclear Information System (INIS)

    Stangenberg, F.

    1972-01-01

    In this report experimental results measured at the 1:5-model of the prestressed concrete pressure vessel of the THTR-nuclear power station Schmehausen in 1971, are compared with the results of axis-symmetrical computations. Linear-elastic computations were performed as well as approximate computations for overload pressures taking into consideration the influences of the load history (prestressing, temperature, creep) and the effects of the steel components. (orig.) [de

  2. Comparison of vibration test results for Atucha II NPP and large scale concrete block models

    International Nuclear Information System (INIS)

    Iizuka, S.; Konno, T.; Prato, C.A.

    2001-01-01

    In order to study the soil structure interaction of reactor building that could be constructed on a Quaternary soil, a comparison study of the soil structure interaction springs was performed between full scale vibration test results of Atucha II NPP and vibration test results of large scale concrete block models constructed on Quaternary soil. This comparison study provides a case data of soil structure interaction springs on Quaternary soil with different foundation size and stiffness. (author)

  3. Models of Automation Surprise: Results of a Field Survey in Aviation

    Directory of Open Access Journals (Sweden)

    Robert De Boer

    2017-09-01

    Full Text Available Automation surprises in aviation continue to be a significant safety concern and the community’s search for effective strategies to mitigate them are ongoing. The literature has offered two fundamentally divergent directions, based on different ideas about the nature of cognition and collaboration with automation. In this paper, we report the results of a field study that empirically compared and contrasted two models of automation surprises: a normative individual-cognition model and a sensemaking model based on distributed cognition. Our data prove a good fit for the sense-making model. This finding is relevant for aviation safety, since our understanding of the cognitive processes that govern human interaction with automation drive what we need to do to reduce the frequency of automation-induced events.

  4. Results on Standard Model Higgs Boson searches at high mass at the LHC

    International Nuclear Information System (INIS)

    Gao, Yanyan

    2014-01-01

    We present results from searches for the standard model Higgs boson with a mass greater than 200 GeV in pp collisions at √(s)=7 TeV. The data are collected at the LHC with both ATLAS and CMS detectors, and correspond to integrated luminosity of 5 fb -1 each. Searches are performed in the 2 main decay modes WW and ZZ. No significant excess of events above the standard model background expectations is observed, and upper limits on the Higgs boson production relative to the standard model expectation are derived. A standard model Higgs boson is excluded in the mass range up to 539 GeV or 600 GeV at 95% confidence level by the ATLAS or CMS experiments respectively. (author)

  5. Model unspecific search in CMS. Results at 8 TeV

    Energy Technology Data Exchange (ETDEWEB)

    Albert, Andreas; Duchardt, Deborah; Hebbeker, Thomas; Knutzen, Simon; Lieb, Jonas; Meyer, Arnd; Pook, Tobias; Roemer, Jonas [III. Physikalisches Institut A, RWTH Aachen University (Germany)

    2016-07-01

    In the year 2012, CMS collected a total data set of approximately 20 fb{sup -1} in proton-proton collisions at √(s)=8 TeV. Dedicated searches for physics beyond the standard model are commonly designed with the signatures of a given theoretical model in mind. While this approach allows for an optimised sensitivity to the sought-after signal, it may cause unexpected phenomena to be overlooked. In a complementary approach, the Model Unspecific Search in CMS (MUSiC) analyses CMS data in a general way. Depending on the reconstructed final state objects (e.g. electrons), collision events are sorted into classes. In each of the classes, the distributions of selected kinematic variables are compared to standard model simulation. An automated statistical analysis is performed to quantify the agreement between data and prediction. In this talk, the analysis concept is introduced and selected results of the analysis of the 2012 CMS data set are presented.

  6. Maritime Aerosol Network as a Component of AERONET - First Results and Comparison with Global Aerosol Models and Satellite Retrievals

    Science.gov (United States)

    Smirnov, A.; Holben, B. N.; Giles, D. M.; Slutsker, I.; O'Neill, N. T.; Eck, T. F.; Macke, A.; Croot, P.; Courcoux, Y.; Sakerin, S. M.; hide

    2011-01-01

    The Maritime Aerosol Network (MAN) has been collecting data over the oceans since November 2006. Over 80 cruises were completed through early 2010 with deployments continuing. Measurement areas included various parts of the Atlantic Ocean, the Northern and Southern Pacific Ocean, the South Indian Ocean, the Southern Ocean, the Arctic Ocean and inland seas. MAN deploys Microtops handheld sunphotometers and utilizes a calibration procedure and data processing traceable to AERONET. Data collection included areas that previously had no aerosol optical depth (AOD) coverage at all, particularly vast areas of the Southern Ocean. The MAN data archive provides a valuable resource for aerosol studies in maritime environments. In the current paper we present results of AOD measurements over the oceans, and make a comparison with satellite AOD retrievals and model simulations.

  7. Maritime aerosol network as a component of AERONET – first results and comparison with global aerosol models and satellite retrievals

    Directory of Open Access Journals (Sweden)

    A. Smirnov

    2011-03-01

    Full Text Available The Maritime Aerosol Network (MAN has been collecting data over the oceans since November 2006. Over 80 cruises were completed through early 2010 with deployments continuing. Measurement areas included various parts of the Atlantic Ocean, the Northern and Southern Pacific Ocean, the South Indian Ocean, the Southern Ocean, the Arctic Ocean and inland seas. MAN deploys Microtops hand-held sunphotometers and utilizes a calibration procedure and data processing traceable to AERONET. Data collection included areas that previously had no aerosol optical depth (AOD coverage at all, particularly vast areas of the Southern Ocean. The MAN data archive provides a valuable resource for aerosol studies in maritime environments. In the current paper we present results of AOD measurements over the oceans, and make a comparison with satellite AOD retrievals and model simulations.

  8. Global Monthly CO2 Flux Inversion Based on Results of Terrestrial Ecosystem Modeling

    Science.gov (United States)

    Deng, F.; Chen, J.; Peters, W.; Krol, M.

    2008-12-01

    Most of our understanding of the sources and sinks of atmospheric CO2 has come from inverse studies of atmospheric CO2 concentration measurements. However, the number of currently available observation stations and our ability to simulate the diurnal planetary boundary layer evolution over continental regions essentially limit the number of regions that can be reliably inverted globally, especially over continental areas. In order to overcome these restrictions, a nested inverse modeling system was developed based on the Bayesian principle for estimating carbon fluxes of 30 regions in North America and 20 regions for the rest of the globe. Inverse modeling was conducted in monthly steps using CO2 concentration measurements of 5 years (2000 - 2005) with the following two models: (a) An atmospheric transport model (TM5) is used to generate the transport matrix where the diurnal variation n of atmospheric CO2 concentration is considered to enhance the use of the afternoon-hour average CO2 concentration measurements over the continental sites. (b) A process-based terrestrial ecosystem model (BEPS) is used to produce hourly step carbon fluxes, which could minimize the limitation due to our inability to solve the inverse problem in a high resolution, as the background of our inversion. We will present our recent results achieved through a combination of the bottom-up modeling with BEPS and the top-down modeling based on TM5 driven by offline meteorological fields generated by the European Centre for Medium Range Weather Forecast (ECMFW).

  9. Comparison of results of experimental research with numerical calculations of a model one-sided seal

    Directory of Open Access Journals (Sweden)

    Joachimiak Damian

    2015-06-01

    Full Text Available Paper presents the results of experimental and numerical research of a model segment of a labyrinth seal for a different wear level. The analysis covers the extent of leakage and distribution of static pressure in the seal chambers and the planes upstream and downstream of the segment. The measurement data have been compared with the results of numerical calculations obtained using commercial software. Based on the flow conditions occurring in the area subjected to calculations, the size of the mesh defined by parameter y+ has been analyzed and the selection of the turbulence model has been described. The numerical calculations were based on the measurable thermodynamic parameters in the seal segments of steam turbines. The work contains a comparison of the mass flow and distribution of static pressure in the seal chambers obtained during the measurement and calculated numerically in a model segment of the seal of different level of wear.

  10. Technogenic Rock Dumps Physical Properties' Prognosis via Results of the Structure Numerical Modeling

    Directory of Open Access Journals (Sweden)

    Markov Sergey

    2017-01-01

    Full Text Available Understanding of internal structure of the technogenic rock dumps (gob dumps is required condition for estimation of using ones as filtration massifs for treatment of mine wastewater. Internal structure of gob piles greatly depends on dumping technology to applying restrictions for use them as filtration massifs. Numerical modelling of gob dumps allows adequately estimate them physical parameters, as a filtration coefficient, density, etc. The gob dumps numerical modelling results given in this article, in particular was examined grain size distribution of determined fractions depend on dump height. Shown, that filtration coefficient is in a nonlinear dependence on amount of several fractions of rock in gob dump. The numerical model adequacy both the gob structure and the dependence of filtration coefficient from gob height acknowledged equality of calculated and real filtration coefficient values. The results of this research can be apply to peripheral dumping technology.

  11. Previous experiences shape adaptive mate preferences

    NARCIS (Netherlands)

    Fawcett, Tim W.; Bleay, Colin

    2009-01-01

    Existing models of mate choice assume that individuals have perfect knowledge of their own ability to attract a mate and can adjust their preferences accordingly. However, real animals will typically be uncertain of their own attractiveness. A potentially useful source of information on this is the

  12. Results of an interactively coupled atmospheric chemistry - general circulation model. Comparison with observations

    Energy Technology Data Exchange (ETDEWEB)

    Hein, R.; Dameris, M.; Schnadt, C. [and others

    2000-01-01

    An interactively coupled climate-chemistry model which enables a simultaneous treatment of meteorology and atmospheric chemistry and their feedbacks is presented. This is the first model, which interactively combines a general circulation model based on primitive equations with a rather complex model of stratospheric and tropospheric chemistry, and which is computational efficient enough to allow long-term integrations with currently available computer resources. The applied model version extends from the Earth's surface up to 10 hPa with a relatively high number (39) of vertical levels. We present the results of a present-day (1990) simulation and compare it to available observations. We focus on stratospheric dynamics and chemistry relevant to describe the stratospheric ozone layer. The current model version ECHAM4.L39(DLR)/CHEM can realistically reproduce stratospheric dynamics in the Arctic vortex region, including stratospheric warming events. This constitutes a major improvement compared to formerly applied model versions. However, apparent shortcomings in Antarctic circulation and temperatures persist. The seasonal and interannual variability of the ozone layer is simulated in accordance with observations. Activation and deactivation of chlorine in the polar stratospheric vortices and their interhemispheric differences are reproduced. The consideration of the chemistry feedback on dynamics results in an improved representation of the spatial distribution of stratospheric water vapor concentrations, i.e., the simulated meriodional water vapor gradient in the stratosphere is realistic. The present model version constitutes a powerful tool to investigate, for instance, the combined direct and indirect effects of anthropogenic trace gas emissions, and the future evolution of the ozone layer. (orig.)

  13. From sub-source to source: Interpreting results of biological trace investigations using probabilistic models

    NARCIS (Netherlands)

    Oosterman, W.T.; Kokshoorn, B.; Maaskant-van Wijk, P.A.; de Zoete, J.

    2015-01-01

    The current method of reporting a putative cell type is based on a non-probabilistic assessment of test results by the forensic practitioner. Additionally, the association between donor and cell type in mixed DNA profiles can be exceedingly complex. We present a probabilistic model for

  14. An Associative Index Model for the Results List Based on Vannevar Bush's Selection Concept

    Science.gov (United States)

    Cole, Charles; Julien, Charles-Antoine; Leide, John E.

    2010-01-01

    Introduction: We define the results list problem in information search and suggest the "associative index model", an ad-hoc, user-derived indexing solution based on Vannevar Bush's description of an associative indexing approach for his memex machine. We further define what selection means in indexing terms with reference to Charles…

  15. Predictive Modeling of a Paradigm Mechanical Cooling Tower Model: II. Optimal Best-Estimate Results with Reduced Predicted Uncertainties

    Directory of Open Access Journals (Sweden)

    Ruixian Fang

    2016-09-01

    Full Text Available This work uses the adjoint sensitivity model of the counter-flow cooling tower derived in the accompanying PART I to obtain the expressions and relative numerical rankings of the sensitivities, to all model parameters, of the following model responses: (i outlet air temperature; (ii outlet water temperature; (iii outlet water mass flow rate; and (iv air outlet relative humidity. These sensitivities are subsequently used within the “predictive modeling for coupled multi-physics systems” (PM_CMPS methodology to obtain explicit formulas for the predicted optimal nominal values for the model responses and parameters, along with reduced predicted standard deviations for the predicted model parameters and responses. These explicit formulas embody the assimilation of experimental data and the “calibration” of the model’s parameters. The results presented in this work demonstrate that the PM_CMPS methodology reduces the predicted standard deviations to values that are smaller than either the computed or the experimentally measured ones, even for responses (e.g., the outlet water flow rate for which no measurements are available. These improvements stem from the global characteristics of the PM_CMPS methodology, which combines all of the available information simultaneously in phase-space, as opposed to combining it sequentially, as in current data assimilation procedures.

  16. Assessment of Energy Removal Impacts on Physical Systems: Hydrodynamic Model Domain Expansion and Refinement, and Online Dissemination of Model Results

    International Nuclear Information System (INIS)

    Yang, Zhaoqing; Khangaonkar, Tarang; Wang, Taiping

    2010-01-01

    In this report we describe the (1) the expansion of the PNNL hydrodynamic model domain to include the continental shelf along the coasts of Washington, Oregon, and Vancouver Island; and (2) the approach and progress in developing the online/Internet disseminations of model results and outreach efforts in support of the Puget Sound Operational Forecast System (PS-OPF). Submittal of this report completes the work on Task 2.1.2, Effects of Physical Systems, Subtask 2.1.2.1, Hydrodynamics, for fiscal year 2010 of the Environmental Effects of Marine and Hydrokinetic Energy project.

  17. Dynamic analysis of ITER tokamak. Based on results of vibration test using scaled model

    International Nuclear Information System (INIS)

    Takeda, Nobukazu; Kakudate, Satoshi; Nakahira, Masataka

    2005-01-01

    The vibration experiments of the support structures with flexible plates for the ITER major components such as toroidal field coil (TF coil) and vacuum vessel (VV) were performed using small-sized flexible plates aiming to obtain its basic mechanical characteristics such as dependence of the stiffness on the loading angle. The experimental results were compared with the analytical ones in order to estimate an adequate analytical model for ITER support structure with flexible plates. As a result, the bolt connection of the flexible plates on the base plate strongly affected on the stiffness of the flexible plates. After studies of modeling the connection of the bolts, it is found that the analytical results modeling the bolts with finite stiffness only in the axial direction and infinite stiffness in the other directions agree well with the experimental ones. Based on this, numerical analysis regarding the actual support structure of the ITER VV and TF coil was performed. The support structure composed of flexible plates and connection bolts was modeled as a spring composed of only two spring elements simulating the in-plane and out-of-plane stiffness of the support structure with flexible plates including the effect of connection bolts. The stiffness of both spring models for VV and TF coil agree well with that of shell models, simulating actual structures such as flexible plates and connection bolts based on the experimental results. It is therefore found that the spring model with the only two values of stiffness enables to simplify the complicated support structure with flexible plates for the dynamic analysis of the VV and TF coil. Using the proposed spring model, the dynamic analysis of the VV and TF coil for the ITER were performed to estimate the integrity under the design earthquake. As a result, it is found that the maximum relative displacement of 8.6 mm between VV and TF coil is much less than 100 mm, so that the integrity of the VV and TF coil of the

  18. [Electronic cigarettes - effects on health. Previous reports].

    Science.gov (United States)

    Napierała, Marta; Kulza, Maksymilian; Wachowiak, Anna; Jabłecka, Katarzyna; Florek, Ewa

    2014-01-01

    Currently very popular in the market of tobacco products have gained electronic cigarettes (ang. E-cigarettes). These products are considered to be potentially less harmful in compared to traditional tobacco products. However, current reports indicate that the statements of the producers regarding to the composition of the e- liquids not always are sufficient, and consumers often do not have reliable information on the quality of the product used by them. This paper contain a review of previous reports on the composition of e-cigarettes and their impact on health. Most of the observed health effects was related to symptoms of the respiratory tract, mouth, throat, neurological complications and sensory organs. Particularly hazardous effects of the e-cigarettes were: pneumonia, congestive heart failure, confusion, convulsions, hypotension, aspiration pneumonia, face second-degree burns, blindness, chest pain and rapid heartbeat. In the literature there is no information relating to passive exposure by the aerosols released during e-cigarette smoking. Furthermore, the information regarding to the use of these products in the long term are not also available.

  19. Furthering our Understanding of Land Surface Interactions using SVAT modelling: Results from SimSphere's Validation

    Science.gov (United States)

    North, Matt; Petropoulos, George; Ireland, Gareth; Rendal, Daisy; Carlson, Toby

    2015-04-01

    With current predicted climate change, there is an increased requirement to gain knowledge on the terrestrial biosphere, for numerous agricultural, hydrological and meteorological applications. To this end, Soil Vegetation Atmospheric Transfer (SVAT) models are quickly becoming the preferred scientific tool to monitor, at fine temporal and spatial resolutions, detailed information on numerous parameters associated with Earth system interactions. Validation of any model is critical to assess its accuracy, generality and realism to distinctive ecosystems and subsequently acts as important step before its operational distribution. In this study, the SimSphere SVAT model has been validated to fifteen different sites of the FLUXNET network, where model performance was statistically evaluated by directly comparing the model predictions vs in situ data, for cloud free days with a high energy balance closure. Specific focus is given to the models ability to simulate parameters associated with the energy balance, namely Shortwave Incoming Solar Radiation (Rg), Net Radiation (Rnet), Latent Heat (LE), Sensible Heat (H), Air Temperature at 1.3m (Tair 1.3m) and Air temperature at 50m (Tair 50m). Comparisons were performed for a number distinctive ecosystem types and for 150 days in total using in-situ data from ground observational networks acquired from the year 2011 alone. Evaluation of the models' coherence to reality was evaluated on the basis of a series of statistical parameters including RMSD, R2, Scatter, Bias, MAE , NASH index, Slope and Intercept. Results showed good to very good agreement between predicted and observed datasets, particularly so for LE, H, Tair 1.3m and Tair 50m where mean error distribution values indicated excellent model performance. Due to the systematic underestimation, poorer simulation accuracies were exhibited for Rg and Rnet, yet all values reported are still analogous to other validatory studies of its kind. In overall, the model

  20. Is Previous Respiratory Disease a Risk Factor for Lung Cancer?

    Science.gov (United States)

    Denholm, Rachel; Schüz, Joachim; Straif, Kurt; Stücker, Isabelle; Jöckel, Karl-Heinz; Brenner, Darren R.; De Matteis, Sara; Boffetta, Paolo; Guida, Florence; Brüske, Irene; Wichmann, Heinz-Erich; Landi, Maria Teresa; Caporaso, Neil; Siemiatycki, Jack; Ahrens, Wolfgang; Pohlabeln, Hermann; Zaridze, David; Field, John K.; McLaughlin, John; Demers, Paul; Szeszenia-Dabrowska, Neonila; Lissowska, Jolanta; Rudnai, Peter; Fabianova, Eleonora; Dumitru, Rodica Stanescu; Bencko, Vladimir; Foretova, Lenka; Janout, Vladimir; Kendzia, Benjamin; Peters, Susan; Behrens, Thomas; Vermeulen, Roel; Brüning, Thomas; Kromhout, Hans

    2014-01-01

    Rationale: Previous respiratory diseases have been associated with increased risk of lung cancer. Respiratory conditions often co-occur and few studies have investigated multiple conditions simultaneously. Objectives: Investigate lung cancer risk associated with chronic bronchitis, emphysema, tuberculosis, pneumonia, and asthma. Methods: The SYNERGY project pooled information on previous respiratory diseases from 12,739 case subjects and 14,945 control subjects from 7 case–control studies conducted in Europe and Canada. Multivariate logistic regression models were used to investigate the relationship between individual diseases adjusting for co-occurring conditions, and patterns of respiratory disease diagnoses and lung cancer. Analyses were stratified by sex, and adjusted for age, center, ever-employed in a high-risk occupation, education, smoking status, cigarette pack-years, and time since quitting smoking. Measurements and Main Results: Chronic bronchitis and emphysema were positively associated with lung cancer, after accounting for other respiratory diseases and smoking (e.g., in men: odds ratio [OR], 1.33; 95% confidence interval [CI], 1.20–1.48 and OR, 1.50; 95% CI, 1.21–1.87, respectively). A positive relationship was observed between lung cancer and pneumonia diagnosed 2 years or less before lung cancer (OR, 3.31; 95% CI, 2.33–4.70 for men), but not longer. Co-occurrence of chronic bronchitis and emphysema and/or pneumonia had a stronger positive association with lung cancer than chronic bronchitis “only.” Asthma had an inverse association with lung cancer, the association being stronger with an asthma diagnosis 5 years or more before lung cancer compared with shorter. Conclusions: Findings from this large international case–control consortium indicate that after accounting for co-occurring respiratory diseases, chronic bronchitis and emphysema continue to have a positive association with lung cancer. PMID:25054566

  1. Diffusion and sorption on hardened cement pastes - experiments and modelling results

    Energy Technology Data Exchange (ETDEWEB)

    Jakob, A.; Sarott, F.-A.; Spieler, P.

    1999-08-01

    estimates of the fit-parameter values, correlation coefficients and also, as a measure of the goodness of the fits, the minimum values for the {chi}{sup 2}-merit function. Most of the models yielded an excellent agreement between measurements and calculated breakthrough curves but with best-fit values which are inconsistent with independent measurements. K{sub d} -values from modelling through-diffusion experiments may be orders of magnitude smaller than values obtained using batch sorption experiments. The inadequacy of the models became obvious when the predicted tracer uptake based on the preceding best-fit parameter values was compared with measurements. As a rule, the models failed to predict the correct time behaviour of the amount of tracer taken up. Only caesium seems to act as a conservative tracer, because the simplest models approximately reproduce both the breakthrough curves and the experimental data for tracer uptake. Finally, to obtain further information on the homogeneity of the specimens and retarding mechanisms, for two of the four nickel experiments, the boundary condition at the high-concentration side was changed to measure the out-diffusion of the tracer previously taken up. This was done by quickly replacing the high tracer concentration reservoir by a compartment with artificial pore water. In steady-state the concentration profile across the sample should be a linear function of space, and predictions based on a simple model are possible provided that the porous material is homogeneous. With such an experiment we were able to test this underlying assumption for a homogeneous tracer distribution. The analysis of both experiments, however, clearly demonstrated that such an assumption - for nickel as tracer - must be rejected. (author)

  2. Implementing a continuum of care model for older people - results from a Swedish case study

    Directory of Open Access Journals (Sweden)

    Anna Duner

    2011-11-01

    Full Text Available Introduction: There is a need for integrated care and smooth collaboration between care-providing organisations and professions to create a continuum of care for frail older people. However, collaboration between organisations and professions is often problematic. The aim of this study was to examine the process of implementing a new continuum of care model in a complex organisational context, and illuminate some of the challenges involved. The introduced model strived to connect three organisations responsible for delivering health and social care to older people: the regional hospital, primary health care and municipal eldercare.Methods: The actions of the actors involved in the process of implementing the model were understood to be shaped by the actors' understanding, commitment and ability. This article is based on 44 qualitative interviews performed on four occasions with 26 key actors at three organisational levels within these three organisations.Results and conclusions: The results point to the importance of paying regard to the different cultures of the organisations when implementing a new model. The role of upper management emerged as very important. Furthermore, to be accepted, the model has to be experienced as effectively dealing with real problems in the everyday practice of the actors in the organisations, from the bottom to the top.

  3. Results from a 2 x CO2 simulation with the Canadian Climate Centre general circulation model

    International Nuclear Information System (INIS)

    Boer, G.J.

    1990-01-01

    The Canadian Climate Centre's general circulation model (GCM), GCMII, was used to simulate a doubling of atmospheric carbon dioxide concentration. The experiment was a standard greenhouse gas climate change study, using a three-dimensional atmospheric circulation model coupled to a simple 'slab' ocean and a thermodynamic ice model. This standard experiment retains the sophistication and generality of an atmospheric GCM, is straightforward in its use of simplified ocean and ice models, is comparatively economical of computer time, and permits comparison of results from different models. Features of the second generation GCMII include: higher resolution at T32L10 with a transform grid of 3.75 x 3.75 degree; full diurnal and annual cycles; ocean and sea ice treatment involving specification of ocean transports; modified treatment of land surface processes and hydrology; a parameterization of cloud optical feedback; and a retention of the special application data sets of surface parameters for North America and Europe. Results of the simulation were a globally averaged surface temperature increase of 3.5 degree C; a precipitation and evaporation increase of 3%; an average decrease in soil moisture of 6.6%; a decrease in cloud cover of 2.2%; a 66% decrease in mass of sea ice; and marked changes in other quantities in the polar region. 2 refs., 2 figs., 2 tabs

  4. Implementing a continuum of care model for older people - results from a Swedish case study

    Directory of Open Access Journals (Sweden)

    Anna Duner

    2011-11-01

    Full Text Available Introduction: There is a need for integrated care and smooth collaboration between care-providing organisations and professions to create a continuum of care for frail older people. However, collaboration between organisations and professions is often problematic. The aim of this study was to examine the process of implementing a new continuum of care model in a complex organisational context, and illuminate some of the challenges involved. The introduced model strived to connect three organisations responsible for delivering health and social care to older people: the regional hospital, primary health care and municipal eldercare. Methods: The actions of the actors involved in the process of implementing the model were understood to be shaped by the actors' understanding, commitment and ability. This article is based on 44 qualitative interviews performed on four occasions with 26 key actors at three organisational levels within these three organisations. Results and conclusions: The results point to the importance of paying regard to the different cultures of the organisations when implementing a new model. The role of upper management emerged as very important. Furthermore, to be accepted, the model has to be experienced as effectively dealing with real problems in the everyday practice of the actors in the organisations, from the bottom to the top.

  5. Development of Test-Analysis Models (TAM) for correlation of dynamic test and analysis results

    Science.gov (United States)

    Angelucci, Filippo; Javeed, Mehzad; Mcgowan, Paul

    1992-01-01

    The primary objective of structural analysis of aerospace applications is to obtain a verified finite element model (FEM). The verified FEM can be used for loads analysis, evaluate structural modifications, or design control systems. Verification of the FEM is generally obtained as the result of correlating test and FEM models. A test analysis model (TAM) is very useful in the correlation process. A TAM is essentially a FEM reduced to the size of the test model, which attempts to preserve the dynamic characteristics of the original FEM in the analysis range of interest. Numerous methods for generating TAMs have been developed in the literature. The major emphasis of this paper is a description of the procedures necessary for creation of the TAM and the correlation of the reduced models with the FEM or the test results. Herein, three methods are discussed, namely Guyan, Improved Reduced System (IRS), and Hybrid. Also included are the procedures for performing these analyses using MSC/NASTRAN. Finally, application of the TAM process is demonstrated with an experimental test configuration of a ten bay cantilevered truss structure.

  6. Response of a laminar premixed flame to flow oscillations: A kinematic model and thermoacoustic instability results

    Energy Technology Data Exchange (ETDEWEB)

    Fleifil, M.; Annaswamy, A.M.; Ghoneim, A.F. [Massachusetts Inst. of Technology, Cambridge, MA (United States); Ghoneim, Z.A. [Ain Shams Univ., Abassia (Egypt)

    1996-09-01

    Combustion instability is a resonance phenomenon that arises due to the coupling between the system acoustics and the unsteady heat release. The constructive feedback between the two processes, which is known to occur as a certain phase relationship between the pressure and the unsteady heat release rate is satisfied, depends on many parameters among which is the acoustic mode, the flame holder characteristics, and the dominant burning pattern. In this paper, the authors construct an analytical model to describe the dynamic response of a laminar premixed flame stabilized on the rim of a tube to velocity oscillation. They consider uniform and nonuniform velocity perturbations superimposed on a pipe flow velocity profile. The model results show that the magnitude of heat release perturbation and its phase with respect to the dynamic perturbation dependent primarily on the flame Strohal number, representing the ratio of the dominant frequency times the tube radius to the laminar burning velocity. In terms of this number, high-frequency perturbations pass through the flame while low frequencies lead to a strong response. The phase with respect to the velocity perturbation behaves in the opposite way. Results of this model are shown to agree with experimental observations and to be useful in determining how the combustion excited model is selected among all the acoustic unstable modes. The model is then used to obtain a time-domain differential equation describing the relationship between the velocity perturbation and the heat release response over the entire frequency range.

  7. Friction torque of wind-turbine pitch bearings – comparison of experimental results with available models

    Directory of Open Access Journals (Sweden)

    M. Stammler

    2018-03-01

    Full Text Available Pitch bearings of wind turbines are large, grease-lubricated rolling bearings that connect the rotor blades with the rotor hub. They are used to turn the rotor blades to control the power output and/or structural loads of the turbine. Common actuators turning the blades are hydraulic cylinders or electrical motor–gearbox combinations. In order to design pitch actuator systems that are able to turn the blades reliably without imposing an excessive power demand, it is necessary to predict the friction torque of pitch bearings for different operating conditions. In this paper, the results of torque measurements under load are presented and compared to results obtained using different calculation models. The results of this comparison indicate the various sources of friction that should be taken into account for a reliable calculation model.

  8. The Agricultural Model Intercomparison and Improvement Project (AgMIP): Progress and Preliminary Results

    Science.gov (United States)

    Rosenzweig, C.

    2011-12-01

    The Agricultural Model Intercomparison and Improvement Project (AgMIP) is a distributed climate-scenario simulation exercise for historical model intercomparison and future climate change conditions with participation of multiple crop and agricultural trade modeling groups around the world. The goals of AgMIP are to improve substantially the characterization of risk of hunger and world food security due to climate change and to enhance adaptation capacity in both developing and developed countries. Recent progress and the current status of AgMIP will be presented, highlighting three areas of activity: preliminary results from crop pilot studies, outcomes from regional workshops, and emerging scientific challenges. AgMIP crop modeling efforts are being led by pilot studies, which have been established for wheat, maize, rice, and sugarcane. These crop-specific initiatives have proven instrumental in testing and contributing to AgMIP protocols, as well as creating preliminary results for aggregation and input to agricultural trade models. Regional workshops are being held to encourage collaborations and set research activities in motion for key agricultural areas. The first of these workshops was hosted by Embrapa and UNICAMP and held in Campinas, Brazil. Outcomes from this meeting have informed crop modeling research activities within South America, AgMIP protocols, and future regional workshops. Several scientific challenges have emerged and are currently being addressed by AgMIP researchers. Areas of particular interest include geospatial weather generation, ensemble methods for climate scenarios and crop models, spatial aggregation of field-scale yields to regional and global production, and characterization of future changes in climate variability.

  9. Results of an interactively coupled atmospheric chemistry – general circulation model: Comparison with observations

    Directory of Open Access Journals (Sweden)

    R. Hein

    Full Text Available The coupled climate-chemistry model ECHAM4.L39(DLR/CHEM is presented which enables a simultaneous treatment of meteorology and atmospheric chemistry and their feedbacks. This is the first model which interactively combines a general circulation model with a chemical model, employing most of the important reactions and species necessary to describe the stratospheric and upper tropospheric ozone chemistry, and which is computationally fast enough to allow long-term integrations with currently available computer resources. This is possible as the model time-step used for the chemistry can be chosen as large as the integration time-step for the dynamics. Vertically the atmosphere is discretized by 39 levels from the surface up to the top layer which is centred at 10 hPa, with a relatively high vertical resolution of approximately 700 m near the extra-tropical tropopause. We present the results of a control simulation representing recent conditions (1990 and compare it to available observations. The focus is on investigations of stratospheric dynamics and chemistry relevant to describe the stratospheric ozone layer. ECHAM4.L39(DLR/CHEM reproduces main features of stratospheric dynamics in the arctic vortex region, including stratospheric warming events. This constitutes a major improvement compared to earlier model versions. However, apparent shortcomings in Antarctic circulation and temperatures persist. The seasonal and interannual variability of the ozone layer is simulated in accordance with observations. Activation and deactivation of chlorine in the polar stratospheric vortices and their inter-hemispheric differences are reproduced. Considering methane oxidation as part of the dynamic-chemistry feedback results in an improved representation of the spatial distribution of stratospheric water vapour concentrations. The current model constitutes a powerful tool to investigate, for instance, the combined direct and indirect effects of anthropogenic

  10. A method for modeling laterally asymmetric proton beamlets resulting from collimation

    Energy Technology Data Exchange (ETDEWEB)

    Gelover, Edgar; Wang, Dongxu; Flynn, Ryan T.; Hyer, Daniel E. [Department of Radiation Oncology, University of Iowa, 200 Hawkins Drive, Iowa City, Iowa 52242 (United States); Hill, Patrick M. [Department of Human Oncology, University of Wisconsin, 600 Highland Avenue, Madison, Wisconsin 53792 (United States); Gao, Mingcheng; Laub, Steve; Pankuch, Mark [Division of Medical Physics, CDH Proton Center, 4455 Weaver Parkway, Warrenville, Illinois 60555 (United States)

    2015-03-15

    Purpose: To introduce a method to model the 3D dose distribution of laterally asymmetric proton beamlets resulting from collimation. The model enables rapid beamlet calculation for spot scanning (SS) delivery using a novel penumbra-reducing dynamic collimation system (DCS) with two pairs of trimmers oriented perpendicular to each other. Methods: Trimmed beamlet dose distributions in water were simulated with MCNPX and the collimating effects noted in the simulations were validated by experimental measurement. The simulated beamlets were modeled analytically using integral depth dose curves along with an asymmetric Gaussian function to represent fluence in the beam’s eye view (BEV). The BEV parameters consisted of Gaussian standard deviations (sigmas) along each primary axis (σ{sub x1},σ{sub x2},σ{sub y1},σ{sub y2}) together with the spatial location of the maximum dose (μ{sub x},μ{sub y}). Percent depth dose variation with trimmer position was accounted for with a depth-dependent correction function. Beamlet growth with depth was accounted for by combining the in-air divergence with Hong’s fit of the Highland approximation along each axis in the BEV. Results: The beamlet model showed excellent agreement with the Monte Carlo simulation data used as a benchmark. The overall passing rate for a 3D gamma test with 3%/3 mm passing criteria was 96.1% between the analytical model and Monte Carlo data in an example treatment plan. Conclusions: The analytical model is capable of accurately representing individual asymmetric beamlets resulting from use of the DCS. This method enables integration of the DCS into a treatment planning system to perform dose computation in patient datasets. The method could be generalized for use with any SS collimation system in which blades, leaves, or trimmers are used to laterally sharpen beamlets.

  11. A method for modeling laterally asymmetric proton beamlets resulting from collimation

    International Nuclear Information System (INIS)

    Gelover, Edgar; Wang, Dongxu; Flynn, Ryan T.; Hyer, Daniel E.; Hill, Patrick M.; Gao, Mingcheng; Laub, Steve; Pankuch, Mark

    2015-01-01

    Purpose: To introduce a method to model the 3D dose distribution of laterally asymmetric proton beamlets resulting from collimation. The model enables rapid beamlet calculation for spot scanning (SS) delivery using a novel penumbra-reducing dynamic collimation system (DCS) with two pairs of trimmers oriented perpendicular to each other. Methods: Trimmed beamlet dose distributions in water were simulated with MCNPX and the collimating effects noted in the simulations were validated by experimental measurement. The simulated beamlets were modeled analytically using integral depth dose curves along with an asymmetric Gaussian function to represent fluence in the beam’s eye view (BEV). The BEV parameters consisted of Gaussian standard deviations (sigmas) along each primary axis (σ x1 ,σ x2 ,σ y1 ,σ y2 ) together with the spatial location of the maximum dose (μ x ,μ y ). Percent depth dose variation with trimmer position was accounted for with a depth-dependent correction function. Beamlet growth with depth was accounted for by combining the in-air divergence with Hong’s fit of the Highland approximation along each axis in the BEV. Results: The beamlet model showed excellent agreement with the Monte Carlo simulation data used as a benchmark. The overall passing rate for a 3D gamma test with 3%/3 mm passing criteria was 96.1% between the analytical model and Monte Carlo data in an example treatment plan. Conclusions: The analytical model is capable of accurately representing individual asymmetric beamlets resulting from use of the DCS. This method enables integration of the DCS into a treatment planning system to perform dose computation in patient datasets. The method could be generalized for use with any SS collimation system in which blades, leaves, or trimmers are used to laterally sharpen beamlets

  12. A method for modeling laterally asymmetric proton beamlets resulting from collimation

    Science.gov (United States)

    Gelover, Edgar; Wang, Dongxu; Hill, Patrick M.; Flynn, Ryan T.; Gao, Mingcheng; Laub, Steve; Pankuch, Mark; Hyer, Daniel E.

    2015-01-01

    Purpose: To introduce a method to model the 3D dose distribution of laterally asymmetric proton beamlets resulting from collimation. The model enables rapid beamlet calculation for spot scanning (SS) delivery using a novel penumbra-reducing dynamic collimation system (DCS) with two pairs of trimmers oriented perpendicular to each other. Methods: Trimmed beamlet dose distributions in water were simulated with MCNPX and the collimating effects noted in the simulations were validated by experimental measurement. The simulated beamlets were modeled analytically using integral depth dose curves along with an asymmetric Gaussian function to represent fluence in the beam’s eye view (BEV). The BEV parameters consisted of Gaussian standard deviations (sigmas) along each primary axis (σx1,σx2,σy1,σy2) together with the spatial location of the maximum dose (μx,μy). Percent depth dose variation with trimmer position was accounted for with a depth-dependent correction function. Beamlet growth with depth was accounted for by combining the in-air divergence with Hong’s fit of the Highland approximation along each axis in the BEV. Results: The beamlet model showed excellent agreement with the Monte Carlo simulation data used as a benchmark. The overall passing rate for a 3D gamma test with 3%/3 mm passing criteria was 96.1% between the analytical model and Monte Carlo data in an example treatment plan. Conclusions: The analytical model is capable of accurately representing individual asymmetric beamlets resulting from use of the DCS. This method enables integration of the DCS into a treatment planning system to perform dose computation in patient datasets. The method could be generalized for use with any SS collimation system in which blades, leaves, or trimmers are used to laterally sharpen beamlets. PMID:25735287

  13. Updated Results from the Michigan Titan Thermospheric General Circulation Model (TTGCM)

    Science.gov (United States)

    Bell, J. M.; Bougher, S. W.; de Lahaye, V.; Waite, J. H.; Ridley, A.

    2006-05-01

    This paper presents updated results from the Michigan Titan Thermospheric General Circulation Model (TTGCM) that was recently unveiled in operational form (Bell et al 2005 Spring AGU). Since then, we have incorporated a suite of chemical reactions for the major neutral constituents in Titan's upper atmosphere (N2, CH4). Additionally, some selected minor neutral constituents and major ionic species are also supported in the framework. At this time, HCN, which remains one of the critical thermally active species in the upper atmosphere, remains specified at all altitudes, utilizing profiles derived from recent Cassini-Huygen's measurements. In addition to these improvements, a parallel effort is underway to develop a non-hydrostatic Titan Thermospheric General Circulation Model for further comparisons. In this work, we emphasize the impacts of self-consistent chemistry on the results of the updated TTGCM relative to its frozen chemistry predecessor. Meanwhile, the thermosphere's thermodynamics remains determined by the interplay of solar EUV forcing and HCN rotational cooling, which is calculated by a full line- by-line radiative transfer routine along the lines of Yelle (1991) and Mueller-Wodarg (2000, 2002). In addition to these primary drivers, a treatment of magnetospheric heating is further tested. The model's results will be compared with both the Cassini INMS data and the model of Mueller-Wodarg (2000,2002).

  14. Energy consumption and economic growth in New Zealand: Results of trivariate and multivariate models

    International Nuclear Information System (INIS)

    Bartleet, Matthew; Gounder, Rukmani

    2010-01-01

    This study examines the energy consumption-growth nexus in New Zealand. Causal linkages between energy and macroeconomic variables are investigated using trivariate demand-side and multivariate production models. Long run and short run relationships are estimated for the period 1960-2004. The estimated results of demand model reveal a long run relationship between energy consumption, real GDP and energy prices. The short run results indicate that real GDP Granger-causes energy consumption without feedback, consistent with the proposition that energy demand is a derived demand. Energy prices are found to be significant for energy consumption outcomes. Production model results indicate a long run relationship between real GDP, energy consumption and employment. The Granger-causality is found from real GDP to energy consumption, providing additional evidence to support the neoclassical proposition that energy consumption in New Zealand is fundamentally driven by economic activities. Inclusion of capital in the multivariate production model shows short run causality from capital to energy consumption. Also, changes in real GDP and employment have significant predictive power for changes in real capital.

  15. Solar Deployment System (SolarDS) Model: Documentation and Sample Results

    Energy Technology Data Exchange (ETDEWEB)

    Denholm, P.; Drury, E.; Margolis, R.

    2009-09-01

    The Solar Deployment System (SolarDS) model is a bottom-up, market penetration model that simulates the potential adoption of photovoltaics (PV) on residential and commercial rooftops in the continental United States through 2030. NREL developed SolarDS to examine the market competitiveness of PV based on regional solar resources, capital costs, electricity prices, utility rate structures, and federal and local incentives. The model uses the projected financial performance of PV systems to simulate PV adoption for building types and regions then aggregates adoption to state and national levels. The main components of SolarDS include a PV performance simulator, a PV annual revenue calculator, a PV financial performance calculator, a PV market share calculator, and a regional aggregator. The model simulates a variety of installed PV capacity for a range of user-specified input parameters. PV market penetration levels from 15 to 193 GW by 2030 were simulated in preliminary model runs. SolarDS results are primarily driven by three model assumptions: (1) future PV cost reductions, (2) the maximum PV market share assumed for systems with given financial performance, and (3) PV financing parameters and policy-driven assumptions, such as the possible future cost of carbon emissions.

  16. A Compact Synchronous Cellular Model of Nonlinear Calcium Dynamics: Simulation and FPGA Synthesis Results.

    Science.gov (United States)

    Soleimani, Hamid; Drakakis, Emmanuel M

    2017-06-01

    Recent studies have demonstrated that calcium is a widespread intracellular ion that controls a wide range of temporal dynamics in the mammalian body. The simulation and validation of such studies using experimental data would benefit from a fast large scale simulation and modelling tool. This paper presents a compact and fully reconfigurable cellular calcium model capable of mimicking Hopf bifurcation phenomenon and various nonlinear responses of the biological calcium dynamics. The proposed cellular model is synthesized on a digital platform for a single unit and a network model. Hardware synthesis, physical implementation on FPGA, and theoretical analysis confirm that the proposed cellular model can mimic the biological calcium behaviors with considerably low hardware overhead. The approach has the potential to speed up large-scale simulations of slow intracellular dynamics by sharing more cellular units in real-time. To this end, various networks constructed by pipelining 10 k to 40 k cellular calcium units are compared with an equivalent simulation run on a standard PC workstation. Results show that the cellular hardware model is, on average, 83 times faster than the CPU version.

  17. Financial analysis and forecasting of the results of small businesses performance based on regression model

    Directory of Open Access Journals (Sweden)

    Svetlana O. Musienko

    2017-03-01

    Full Text Available Objective to develop the economicmathematical model of the dependence of revenue on other balance sheet items taking into account the sectoral affiliation of the companies. Methods using comparative analysis the article studies the existing approaches to the construction of the company management models. Applying the regression analysis and the least squares method which is widely used for financial management of enterprises in Russia and abroad the author builds a model of the dependence of revenue on other balance sheet items taking into account the sectoral affiliation of the companies which can be used in the financial analysis and prediction of small enterprisesrsquo performance. Results the article states the need to identify factors affecting the financial management efficiency. The author analyzed scientific research and revealed the lack of comprehensive studies on the methodology for assessing the small enterprisesrsquo management while the methods used for large companies are not always suitable for the task. The systematized approaches of various authors to the formation of regression models describe the influence of certain factors on the company activity. It is revealed that the resulting indicators in the studies were revenue profit or the company relative profitability. The main drawback of most models is the mathematical not economic approach to the definition of the dependent and independent variables. Basing on the analysis it was determined that the most correct is the model of dependence between revenues and total assets of the company using the decimal logarithm. The model was built using data on the activities of the 507 small businesses operating in three spheres of economic activity. Using the presented model it was proved that there is direct dependence between the sales proceeds and the main items of the asset balance as well as differences in the degree of this effect depending on the economic activity of small

  18. First Test Results of the 150 mm Aperture IR Quadrupole Models for the High Luminosity LHC

    CERN Document Server

    Ambrosio, G; Wanderer, P; Ferracin, P; Sabbi, G

    2017-01-01

    The High Luminosity upgrade of the LHC at CERN will use large aperture (150 mm) quadrupole magnets to focus the beams at the interaction points. The high field in the coils requires Nb$_{3}$Sn superconductor technology, which has been brought to maturity by the LHC Accelerator Re-search Program (LARP) over the last 10 years. The key design targets for the new IR quadrupoles were established in 2012, and fabrication of model magnets started in 2014. This paper discusses the results from the first single short coil test and from the first short quadrupole model test. Remaining challenges and plans to address them are also presented and discussed.

  19. Exact results for survival probability in the multistate Landau-Zener model

    International Nuclear Information System (INIS)

    Volkov, M V; Ostrovsky, V N

    2004-01-01

    An exact formula is derived for survival probability in the multistate Landau-Zener model in the special case where the initially populated state corresponds to the extremal (maximum or minimum) slope of a linear diabatic potential curve. The formula was originally guessed by S Brundobler and V Elzer (1993 J. Phys. A: Math. Gen. 26 1211) based on numerical calculations. It is a simple generalization of the expression for the probability of diabatic passage in the famous two-state Landau-Zener model. Our result is obtained via analysis and summation of the entire perturbation theory series

  20. Parameter uncertainty and model predictions: a review of Monte Carlo results

    International Nuclear Information System (INIS)

    Gardner, R.H.; O'Neill, R.V.

    1979-01-01

    Studies of parameter variability by Monte Carlo analysis are reviewed using repeated simulations of the model with randomly selected parameter values. At the beginning of each simulation, parameter values are chosen from specific frequency distributions. This process is continued for a number of iterations sufficient to converge on an estimate of the frequency distribution of the output variables. The purpose was to explore the general properties of error propagaton in models. Testing the implicit assumptions of analytical methods and pointing out counter-intuitive results produced by the Monte Carlo approach are additional points covered

  1. A Module for Graphical Display of Model Results with the CBP Toolbox

    Energy Technology Data Exchange (ETDEWEB)

    Smith, F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-04-21

    This report describes work performed by the Savannah River National Laboratory (SRNL) in fiscal year 2014 to add enhanced graphical capabilities to display model results in the Cementitious Barriers Project (CBP) Toolbox. Because Version 2.0 of the CBP Toolbox has just been released, the graphing enhancements described in this report have not yet been integrated into a new version of the Toolbox. Instead they have been tested using a standalone GoldSim model and, while they are substantially complete, may undergo further refinement before full implementation. Nevertheless, this report is issued to document the FY14 development efforts which will provide a basis for further development of the CBP Toolbox.

  2. First Test Results of the 150 mm Aperture IR Quadrupole Models for the High Luminosity LHC

    Energy Technology Data Exchange (ETDEWEB)

    Ambrosio, G. [Fermilab; Chlachidze, G. [Fermilab; Wanderer, P. [Brookhaven; Ferracin, P. [CERN; Sabbi, G. [LBNL, Berkeley

    2016-10-06

    The High Luminosity upgrade of the LHC at CERN will use large aperture (150 mm) quadrupole magnets to focus the beams at the interaction points. The high field in the coils requires Nb3Sn superconductor technology, which has been brought to maturity by the LHC Accelerator Re-search Program (LARP) over the last 10 years. The key design targets for the new IR quadrupoles were established in 2012, and fabrication of model magnets started in 2014. This paper discusses the results from the first single short coil test and from the first short quadrupole model test. Remaining challenges and plans to address them are also presented and discussed.

  3. Strategy for magnetic resonance imaging of the head: results of a semi-empirical model. Part 1

    International Nuclear Information System (INIS)

    Droege, R.T.; Wiener, S.N.; Rzeszotarski, M.S.

    1984-01-01

    This paper is an introduction to lesion detection problems of MR. A mathematical model previously developed for normal anatomy has been extended to predict the appearance of any hypothetical lesion in magnetic (MR) images of the head. The model is applied to selected clinical images to demonstrate the loss of lesion visibility attributable to ''crossover'' and ''boundary effect.'' The model is also used to explain the origins of these problems, and to demonstrate that appropriate gray-scale manipulations can remedy these problems

  4. Performances of the snow accumulation melting model SAMM: results in the Northern Apennines test area

    Science.gov (United States)

    Lagomarsino, Daniela; Martelloni, Gianluca; Segoni, Samuele; Catani, Filippo; Fanti, Riccardo

    2013-04-01

    In this work we propose a snow accumulation-melting model (SAMM) to forecast the snowpack height and we compare the results with a simple temperature index model and an improved version of the latter.For this purpose we used rainfall, temperature and snowpack thickness 5-years data series from 7 weather stations in the Northern Apennines (Emilia Romagna Region, Italy). SAMM is based on two modules modelling the snow accumulation and the snowmelt processes. Each module is composed by two equations: a mass conservation equation is solved to model snowpack thickness and an empirical equation is used for the snow density. The processes linked to the accumulation/depletion of the snowpack (e.g. compression of the snowpack due to newly fallen snow and effects of rainfall) are modelled identifying limiting and inhibitory factors according to a kinetic approach. The model depends on 13 empirical parameters, whose optimal values were defined with an optimization algorithm (simplex flexible) using calibration measures of snowpack thickness. From an operational point of view, SAMM uses as input data only temperature and rainfall measurements, bringing the additional advantage of a relatively easy implementation. In order to verify the improvement of SAMM with respect to a temperature-index model, the latter was applied considering, for the amount of snow melt, the following equation: M = fm(T-T0), where M is hourly melt, fm is the melting factor and T0 is a threshold temperature. In this case the calculation of the depth of the snowpack requires the use of 3 parameters: fm, T0 and ?0 (the mean density of the snowpack). We also performed a simulation by replacing the SAMM melting module with the above equation and leaving unchanged the accumulation module: in this way we obtained a model with 9 parameters. The simulations results suggest that any further extension of the simple temperature index model brings some improvements with a consequent decrease of the mean error

  5. Channel flow and trichloroethylene treatment in a partly iron-filled fracture: Experimental and model results

    Science.gov (United States)

    Cai, Zuansi; Merly, Corrine; Thomson, Neil R.; Wilson, Ryan D.; Lerner, David N.

    2007-08-01

    Technical developments have now made it possible to emplace granular zero-valent iron (Fe 0) in fractured media to create a Fe 0 fracture reactive barrier (Fe 0 FRB) for the treatment of contaminated groundwater. To evaluate this concept, we conducted a laboratory experiment in which trichloroethylene (TCE) contaminated water was flushed through a single uniform fracture created between two sandstone blocks. This fracture was partly filled with what was intended to be a uniform thickness of iron. Partial treatment of TCE by iron demonstrated that the concept of a Fe 0 FRB is practical, but was less than anticipated for an iron layer of uniform thickness. When the experiment was disassembled, evidence of discrete channelised flow was noted and attributed to imperfect placement of the iron. To evaluate the effect of the channel flow, an explicit Channel Model was developed that simplifies this complex flow regime into a conceptualised set of uniform and parallel channels. The mathematical representation of this conceptualisation directly accounts for (i) flow channels and immobile fluid arising from the non-uniform iron placement, (ii) mass transfer from the open fracture to iron and immobile fluid regions, and (iii) degradation in the iron regions. A favourable comparison between laboratory data and the results from the developed mathematical model suggests that the model is capable of representing TCE degradation in fractures with non-uniform iron placement. In order to apply this Channel Model concept to a Fe 0 FRB system, a simplified, or implicit, Lumped Channel Model was developed where the physical and chemical processes in the iron layer and immobile fluid regions are captured by a first-order lumped rate parameter. The performance of this Lumped Channel Model was compared to laboratory data, and benchmarked against the Channel Model. The advantages of the Lumped Channel Model are that the degradation of TCE in the system is represented by a first

  6. A comparison of results from groundwater flow modelling for two conceptual hydrogeological models for the Konrad site

    International Nuclear Information System (INIS)

    Arens, G.; Fein, E.; Storck, R.

    1991-01-01

    Radioactive wastes with negligible heat production are planned to be disposed of into a deep iron ore formation at the Konrad site. This repository will be bedded in a low permeable formation called Oxfordian in a depth of 800 - 1300 m below the surface. The host formation is largely covered with clay of a few hundred meters thickness. The hydrogeological model area has an extension of 14 km in the west-east and 47 km in the north-south direction. The geological formations within the model area are disturbed by several fractured zones with a vertical extension of several hundred meters intersecting different horizontal layers. Due to this fact two hydrogeological models have been developed: The first one handles the fractured zones by globally increased permeabilities of the geological formations. The second handles the fractured zones by locally increased permeabilities, leaving the permeabilities of undisturbed areas unchanged. For both models, groundwater flow calculations have been carried out including parameter variations of permeability values. The results of the calculations are presented as flow paths which are compared for both models. Computer code used: SWIFT. 1 fig., 3 tabs., 3 refs

  7. A comparison of simulation results from two terrestrial carbon cycle models using three climate data sets

    International Nuclear Information System (INIS)

    Ito, Akihiko; Sasai, Takahiro

    2006-01-01

    This study addressed how different climate data sets influence simulations of the global terrestrial carbon cycle. For the period 1982-2001, we compared the results of simulations based on three climate data sets (NCEP/NCAR, NCEP/DOE AMIP-II and ERA40) employed in meteorological, ecological and biogeochemical studies and two different models (BEAMS and Sim-CYCLE). The models differed in their parameterizations of photosynthetic and phenological processes but used the same surface climate (e.g. shortwave radiation, temperature and precipitation), vegetation, soil and topography data. The three data sets give different climatic conditions, especially for shortwave radiation, in terms of long-term means, linear trends and interannual variability. Consequently, the simulation results for global net primary productivity varied by 16%-43% only from differences in the climate data sets, especially in these regions where the shortwave radiation data differed markedly: differences in the climate data set can strongly influence simulation results. The differences among the climate data set and between the two models resulted in slightly different spatial distribution and interannual variability in the net ecosystem carbon budget. To minimize uncertainty, we should pay attention to the specific climate data used. We recommend developing an accurate standard climate data set for simulation studies

  8. Multimillennium changes in dissolved oxygen under global warming: results from an AOGCM and offline ocean biogeochemical model

    Science.gov (United States)

    Yamamoto, A.; Abe-Ouchi, A.; Shigemitsu, M.; Oka, A.; Takahashi, K.; Ohgaito, R.; Yamanaka, Y.

    2016-12-01

    Long-term oceanic oxygen change due to global warming is still unclear; most future projections (such as CMIP5) are only performed until 2100. Indeed, few previous studies using conceptual models project oxygen change in the next thousands of years, showing persistent global oxygen reduction by about 30% in the next 2000 years, even after atmospheric carbon dioxide stops rising. Yet, these models cannot sufficiently represent the ocean circulation change: the key driver of oxygen change. Moreover, considering serious effect oxygen reduction has on marine life and biogeochemical cycling, long-term oxygen change should be projected for higher validity. Therefore, we used a coupled atmosphere-ocean general circulation model (AOGCM) and an offline ocean biogeochemical model, investigating realistic long-term changes in oceanic oxygen concentration and ocean circulation. We integrated these models for 2000 years under atmospheric CO2 doubling and quadrupling. After global oxygen reduction in the first 500 years, oxygen concentration in deep ocean globally recovers and overshoots, despite surface oxygen decrease and weaker Atlantic Meridional Overturning Circulation. Deep ocean convection in the Weddell Sea recovers and overshoots, after initial cessation. Thus, enhanced deep convection and associated Antarctic Bottom Water supply oxygen-rich surface waters to deep ocean, resulting global deep ocean oxygenation. We conclude that the change in ocean circulation in the Southern Ocean potentially drives millennial-scale oxygenation in the deep ocean; contrary to past reported long-term oxygen reduction and general expectation. In presentation, we will discuss the mechanism of response of deep ocean convection in the Weddell Sea and show the volume changes of hypoxic waters.

  9. Advanced Modeling and Uncertainty Quantification for Flight Dynamics; Interim Results and Challenges

    Science.gov (United States)

    Hyde, David C.; Shweyk, Kamal M.; Brown, Frank; Shah, Gautam

    2014-01-01

    into a real-time simulation capability, generating techniques for uncertainty modeling that draw data from multiple modeling sources, and providing a unified database model that includes nominal plus increments for each flight condition. This paper presents status of testing in the BR&T water tunnel and analysis of the resulting data and efforts to characterize these data using alternative modeling methods. Program challenges and issues are also presented.

  10. SAFEGUARDS ENVELOPE: PREVIOUS WORK AND EXAMPLES

    International Nuclear Information System (INIS)

    Metcalf, Richard; Bevill, Aaron; Charlton, William; Bean, Robert

    2008-01-01

    The future expansion of nuclear power will require not just electricity production but fuel cycle facilities such as fuel fabrication and reprocessing plants. As large reprocessing facilities are built in various states, they must be built and operated in a manner to minimize the risk of nuclear proliferation. Process monitoring has returned to the spotlight as an added measure that can increase confidence in the safeguards of special nuclear material (SNM). Process monitoring can be demonstrated to lengthen the allowable inventory period by reducing accountancy requirements, and to reduce the false positive indications. The next logical step is the creation of a Safeguards Envelope, a set of operational parameters and models to maximize anomaly detection and inventory period by process monitoring while minimizing operator impact and false positive rates. A brief example of a rudimentary Safeguards Envelope is presented, and shown to detect synthetic diversions overlaying a measured processing plant data set. This demonstration Safeguards Envelope is shown to increase the confidence that no SNM has been diverted with minimal operator impact, even though it is based on an information sparse environment. While the foundation on which a full Safeguards Envelope can be built has been presented in historical demonstrations of process monitoring, several requirements remain yet unfulfilled. Future work will require reprocessing plant transient models, inclusion of 'non-traditional' operating data, and exploration of new methods of identifying subtle events in transient processes

  11. The impact of air traffic in the NAFC. Model results and measurements

    Energy Technology Data Exchange (ETDEWEB)

    Wauben, W M.F.; Velthoven, P F.J. van; Kelder, H M [Koninklijk Nederlands Meteorologisch Inst., De Bilt (Netherlands)

    1998-12-31

    The impact of aircraft emissions on the atmospheric composition has been investigated with a global chemistry transport model. The model calculations show that aircraft emissions of nitrogen oxides contribute to about 40-80% of the background values of nitrogen oxides in the North Atlantic Flight Corridor (NAFC), and lead to an increase of the background ozone concentrations by about 3-4% in winter and 5-7% in summer. The three-dimensional distributions of ozone, nitrogen oxides and nitric acid, calculated by using analysed meteorological data, have been compared with airborne measurements performed in the North Atlantic Flight Corridor as part of the EC POLINAT project. The agreement between modelled results and observations is reasonably good for ozone, but worse for nitrogen oxides and nitric acid. (author) 12 refs.

  12. Non-local energy density functionals: models plus some exact general results

    International Nuclear Information System (INIS)

    March, N.H.

    2001-02-01

    Holas and March (Phys. Rev. A51, 2040, 1995) gave a formally exact expression for the force - δV xc (r-tilde)/δr-tilde associated with the exchange-correlation potential V xc (r-tilde) of density functional theory. This forged a precise link between first- and second-order density matrices and V xc (r-tilde). Here models are presented in which these low-order matrices can be related to the ground-state electron density. This allows non-local energy density functionals to be constructed within the framework of such models. Finally, results emerging from these models have led to the derivation of some exact 'nuclear cusp' relations for exchange and correlation energy densities in molecules, clusters and condensed phases. (author)

  13. The impact of air traffic in the NAFC. Model results and measurements

    Energy Technology Data Exchange (ETDEWEB)

    Wauben, W.M.F.; Velthoven, P.F.J. van; Kelder, H.M. [Koninklijk Nederlands Meteorologisch Inst., De Bilt (Netherlands)

    1997-12-31

    The impact of aircraft emissions on the atmospheric composition has been investigated with a global chemistry transport model. The model calculations show that aircraft emissions of nitrogen oxides contribute to about 40-80% of the background values of nitrogen oxides in the North Atlantic Flight Corridor (NAFC), and lead to an increase of the background ozone concentrations by about 3-4% in winter and 5-7% in summer. The three-dimensional distributions of ozone, nitrogen oxides and nitric acid, calculated by using analysed meteorological data, have been compared with airborne measurements performed in the North Atlantic Flight Corridor as part of the EC POLINAT project. The agreement between modelled results and observations is reasonably good for ozone, but worse for nitrogen oxides and nitric acid. (author) 12 refs.

  14. Mathematical modeling of ignition of woodlands resulted from accident on the pipeline

    Science.gov (United States)

    Perminov, V. A.; Loboda, E. L.; Reyno, V. V.

    2014-11-01

    Accidents occurring at the sites of pipelines, accompanied by environmental damage, economic loss, and sometimes loss of life. In this paper we calculated the sizes of the possible ignition zones in emergency situations on pipelines located close to the forest, accompanied by the appearance of fireballs. In this paper, using the method of mathematical modeling calculates the maximum size of the ignition zones of vegetation as a result of accidental releases of flammable substances. The paper suggested in the context of the general mathematical model of forest fires give a new mathematical setting and method of numerical solution of a problem of a forest fire modeling. The boundary-value problem is solved numerically using the method of splitting according to physical processes. The dependences of the size of the forest fuel for different amounts of leaked flammable substances and moisture content of vegetation.

  15. The t-J model at small t/j: Numerical, perturbative, and supersymmetric results

    International Nuclear Information System (INIS)

    Barnes, T.; Tennessee Univ., Knoxville, TN

    1991-02-01

    We discuss some recent results for one- and two-hole states in the t-J model at small t/J. These include numerical results (bandwidth determinations and accurate t/J values for 4 x 4 lattice one-hole ground-state level crossings), hopping-parameter perturbation theory (which gives the small-t/J one-hole bandwidth in terms of the static-vacancy ground state), and results at the supersymmetric point t/J = 1/2 (exact results for energies and bandwidths.) The perturbative results leads us to a new conjecture regarding the staggered magnetization of higher-spin states in the two-dimensional Heisenberg model. We also discuss extrapolation of small-t/J results to high-T c parameter values; in the two-hole ground states we find (t/J) λ behavior in the rms hole-hole separation, and an extrapolation to t/J = 3 gives a bulk-limit rms hole-hole separation of ∼ 7 angstrom. 18 refs., 6 figs

  16. Comparison of simulation and experimental results for a model aqueous tert-butanol solution

    Science.gov (United States)

    Overduin, S. D.; Patey, G. N.

    2017-07-01

    Molecular dynamics simulations are used to investigate the behavior of aqueous tert-butanol (TBA) solutions for a range of temperatures, using the CHARMM generalized force field (CGenFF) to model TBA and the TIP4P/2005 or TIP4P-Ew water model. Simulation results for the density, isothermal compressibility, constant pressure heat capacity, and self-diffusion coefficients are in good accord with experimental measurements. Agreement with the experiment is particularly good at low TBA concentration, where experiments have revealed anomalies in a number of thermodynamic properties. Importantly, the CGenFF model does not exhibit liquid-liquid demixing at temperatures between 290 and 320 K (for systems of 32 000 molecules), in contrast with the situation for several other common TBA models [R. Gupta and G. N. Patey, J. Chem. Phys. 137, 034509 (2012)]. However, whereas real water and TBA are miscible at all temperatures where the liquid is stable, we observe some evidence of demixing at 340 K and above. To evaluate the structural properties at low concentrations, we compare with both neutron scattering and recent spectroscopic measurements. This reveals that while the CGenFF model is a definite improvement over other models that have been considered, the TBA molecules still exhibit a tendency to associate at low concentrations that is somewhat stronger than that indicated by experiments. Finally, we discuss the range and decay times of the long-range correlations, providing an indication of the system size and simulation times that are necessary in order to obtain reliable results for certain properties.

  17. Sea ice thermohaline dynamics and biogeochemistry in the Arctic Ocean: Empirical and model results

    Science.gov (United States)

    Duarte, Pedro; Meyer, Amelie; Olsen, Lasse M.; Kauko, Hanna M.; Assmy, Philipp; Rösel, Anja; Itkin, Polona; Hudson, Stephen R.; Granskog, Mats A.; Gerland, Sebastian; Sundfjord, Arild; Steen, Harald; Hop, Haakon; Cohen, Lana; Peterson, Algot K.; Jeffery, Nicole; Elliott, Scott M.; Hunke, Elizabeth C.; Turner, Adrian K.

    2017-07-01

    Large changes in the sea ice regime of the Arctic Ocean have occurred over the last decades justifying the development of models to forecast sea ice physics and biogeochemistry. The main goal of this study is to evaluate the performance of the Los Alamos Sea Ice Model (CICE) to simulate physical and biogeochemical properties at time scales of a few weeks and to use the model to analyze ice algal bloom dynamics in different types of ice. Ocean and atmospheric forcing data and observations of the evolution of the sea ice properties collected from 18 April to 4 June 2015, during the Norwegian young sea ICE expedition, were used to test the CICE model. Our results show the following: (i) model performance is reasonable for sea ice thickness and bulk salinity; good for vertically resolved temperature, vertically averaged Chl a concentrations, and standing stocks; and poor for vertically resolved Chl a concentrations. (ii) Improving current knowledge about nutrient exchanges, ice algal recruitment, and motion is critical to improve sea ice biogeochemical modeling. (iii) Ice algae may bloom despite some degree of basal melting. (iv) Ice algal motility driven by gradients in limiting factors is a plausible mechanism to explain their vertical distribution. (v) Different ice algal bloom and net primary production (NPP) patterns were identified in the ice types studied, suggesting that ice algal maximal growth rates will increase, while sea ice vertically integrated NPP and biomass will decrease as a result of the predictable increase in the area covered by refrozen leads in the Arctic Ocean.

  18. National Rates of Uterine Rupture are not Associated with Rates of Previous Caesarean Delivery

    DEFF Research Database (Denmark)

    Colmorn, Lotte B.; Langhoff-Roos, Jens; Jakobsson, Maija

    2017-01-01

    % of all Nordic deliveries. Information on the comparison population was retrieved from the national medical birth registers. Incidence rate ratios by previous caesarean delivery and intended mode of delivery after caesarean were modelled using Poisson regression. RESULTS: The incidence of uterine rupture......BACKGROUND: Previous caesarean delivery and intended mode of delivery after caesarean are well-known individual risk factors for uterine rupture. We examined if different national rates of uterine rupture are associated with differences in national rates of previous caesarean delivery and intended...... was 7.8/10 000 in Finland and 4.6/10 000 in Denmark. Rates of caesarean (21.3%) and previous caesarean deliveries (11.5%) were highest in Denmark, while the rate of intended vaginal delivery after caesarean was highest in Finland (72%). National rates of uterine rupture were not associated...

  19. Results from flamelet and non-flamelet models for supersonic combustion

    Science.gov (United States)

    Ladeinde, Foluso; Li, Wenhai

    2017-11-01

    Air-breathing propulsion systems (scramjets) have been identified as a viable alternative to rocket engines for improved efficiency. A scramjet engine, which operates at flight Mach numbers around 7 or above, is characterized by the existence of supersonic flow conditions in the combustor. In a dual-mode scramjet, this phenomenon is possible because of the relatively low value of the equivalence ratio and high stagnation temperature, which, together, inhibits thermal choking downstream of transverse injectors. The flamelet method has been our choice for turbulence-combustion interaction modeling and we have extended the basic approach in several dimensions, with a focus on the way the pressure and progress variable are modeled. Improved results have been obtained. We have also examined non-flamelet models, including laminar chemistry (QL), eddy dissipation concept (EDC), and partially-stirred reactor (PaSR). The pressure/progress variable-corrected simulations give better results compared with the original model, with reaction rates that are lower than those from EDC and PaSR. In general, QL tends to over-predict the reaction rate for the supersonic combustion problems investigated in our work.

  20. An analytical model for nanoparticles concentration resulting from infusion into poroelastic brain tissue.

    Science.gov (United States)

    Pizzichelli, G; Di Michele, F; Sinibaldi, E

    2016-02-01

    We consider the infusion of a diluted suspension of nanoparticles (NPs) into poroelastic brain tissue, in view of relevant biomedical applications such as intratumoral thermotherapy. Indeed, the high impact of the related pathologies motivates the development of advanced therapeutic approaches, whose design also benefits from theoretical models. This study provides an analytical expression for the time-dependent NPs concentration during the infusion into poroelastic brain tissue, which also accounts for particle binding onto cells (by recalling relevant results from the colloid filtration theory). Our model is computationally inexpensive and, compared to fully numerical approaches, permits to explicitly elucidate the role of the involved physical aspects (tissue poroelasticity, infusion parameters, NPs physico-chemical properties, NP-tissue interactions underlying binding). We also present illustrative results based on parameters taken from the literature, by considering clinically relevant ranges for the infusion parameters. Moreover, we thoroughly assess the model working assumptions besides discussing its limitations. While not laying any claims of generality, our model can be used to support the development of more ambitious numerical approaches, towards the preliminary design of novel therapies based on NPs infusion into brain tissue. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Daily air quality forecast (gases and aerosols) over Switzerland. Modeling tool description and first results analysis.

    Science.gov (United States)

    Couach, O.; Kirchner, F.; Porchet, P.; Balin, I.; Parlange, M.; Balin, D.

    2009-04-01

    Map3D, the acronym for "Mesoscale Air Pollution 3D modelling", was developed at the EFLUM laboratory (EPFL) and received an INNOGRANTS awards in Summer 2007 in order to move from a research phase to a professional product giving daily air quality forecast. It is intended to give an objective base for political decisions addressing the improvement of regional air quality. This tool is a permanent modelling system which provides daily forecast of the local meteorology and the air pollutant (gases and particles) concentrations. Map3D has been successfully developed and calculates each day at the EPFL site a three days air quality forecast over Europe and the Alps with 50 km and 15 km resolution, respectively (see http://map3d.epfl.ch). The Map3D user interface is a web-based application with a PostgreSQL database. It is written in object-oriented PHP5 on a MVC (Model-View-Controller) architecture. Our prediction system is operational since August 2008. A first validation of the calculations for Switzerland is performed for the period of August 2008 - January 2009 comparing the model results for O3, NO2 and particulates with the results of the Nabel measurements stations. The subject of air pollution regimes (NOX/VOC) and specific indicators application with the forecast will be also addressed.

  2. Modelling of carcinogenic effects resulting from the combined action of radon and smoking

    Energy Technology Data Exchange (ETDEWEB)

    Ryabova, S.V.; Petin, V.G. [Medical Radiological Research Centre, Obninsk (Russian Federation)

    2002-03-01

    A simple mathematical model designed for the description of cell survival [1] and later developed for the evaluation of mutagenic effects [2] was proposed for the optimisation of the determination and prognosis of levels of carcinogenic effects in organisms, resulting from the combined action of different agents. The model postulates that the occurrence of synergism is to be expected as a result of additional carcinogenic damage arising from the interaction of sublesions induced by the two agents under investigation. These molecular sublesions are suggested to be non-carcinogenic, if each agent is taken separately. The main conclusion pertaining to this model is the existence of the highest level of synergistic effect. The model predicts the input values and conditions under which this level is reached. The synergistic effect appeared to decline with any deviation from the optimal value for the ratio of carcinogenic effects produced by each agent alone. These conclusions were verified by comparison with experimental data published by other researchers. (orig.)

  3. Application of the IPCC model to a Brazilian landfill: First results

    International Nuclear Information System (INIS)

    Penteado, Roger; Cavalli, Massimo; Magnano, Enrico; Chiampo, Fulvia

    2012-01-01

    The Intergovernmental Panel on Climate Change gave a methodology to estimate the methane emissions from Municipal Solid Wastes landfills, based on a First Order Decay (FOD) model that assumes biodegradation kinetics depending on the type of wastes. This model can be used to estimate both the National greenhouse gas emissions in the industrialized countries as well as the reductions of these emissions in the developing ones when the Clean Development Mechanism, as defined by the Kyoto Protocol, is implemented. In this paper, the FOD model has been use to evaluate the biogas flow rates emitted by a Brazilian landfill and the results have been compared to the extracted ones: some first results can be useful to evidence the weight of key parameters and do a correct use of the model. - Highlights: ► Landfill biogas is greenhouse gas and fuel at the same time. ► In developing countries its collection can implement Kyoto Protocol mechanisms. ► Biogas collection and exploiting become part of energy policy. ► Project economical balance is based on reliable estimates of generated quantities.

  4. Recent Result from E821 Experiment on Muon g-2 and Unconstrained Minimal Supersymemtric Standard Model

    CERN Document Server

    Komine, S; Yamaguchi, M; Komine, Shinji; Moroi, Takeo; Yamaguchi, Masahiro

    2001-01-01

    Recently, the E821 experiment at the Brookhaven National Laboratory announced their latest result of their muon g-2 measurement which is about 2.6-\\sigma away from the standard model prediction. Taking this result seriously, we examine the possibility to explain this discrepancy by the supersymmetric contribution. Our analysis is performed in the framework of the unconstrained supersymmetric standard model which has free seven parameters relevant to muon g-2. We found that, in the case of large \\tan\\beta, sparticle masses are allowed to be large in the region where the SUSY contribution to the muon g-2 is large enough, and hence the conventional SUSY search may fail even at the LHC. On the contrary, to explain the discrepancy in the case of small \\tan\\beta, we found that (i) sleptons and SU(2)_L gauginos should be light, and (ii) negative search for the Higgs boson severely constrains the model in the framework of the mSUGRA and gauge-mediated model.

  5. The Effect of Treatment Advances on the Mortality Results of Breast Cancer Screening Trials: A Microsimulation Model.

    Science.gov (United States)

    Birnbaum, Jeanette; Gadi, Vijayakrishna K; Markowitz, Elan; Etzioni, Ruth

    2016-02-16

    Mammography trials, which are the primary sources of evidence for screening benefit, were conducted decades ago. Whether advances in systemic therapies have rendered previously observed benefits of screening less significant is unknown. To compare the outcomes of breast cancer screening trials had they been conducted using contemporary systemic treatments with outcomes of trials conducted with previously used treatments. Computer simulation model of 3 virtual screening trials with similar reductions in advanced-stage cancer cases but reflecting treatment patterns in 1975 (prechemotherapy era), 1999, or 2015 (treatment according to receptor status). Meta-analyses of screening and treatment trials; study of dissemination of primary systemic treatments; SEER (Surveillance, Epidemiology, and End Results) registry. U.S. women aged 50 to 74 years. 10 and 25 years. Population. Mammography, chemotherapy, tamoxifen, aromatase inhibitors, and trastuzumab. Breast cancer mortality rate ratio (MRR) and absolute risk reduction (ARR) obtained by the difference in cumulative breast cancer mortality between control and screening groups. At 10 years, screening in a 1975 trial yielded an MRR of 90% and an ARR of 5 deaths per 10,000 women. A 2015 screening trial yielded a 10-year MRR of 90% and an ARR of 3 deaths per 10,000 women. Greater reductions in advanced-stage disease yielded a greater screening effect, but MRRs remained similar across trials. However, ARRs were consistently lower under contemporary treatments. When contemporary treatments were available only for early-stage cases, the MRR was 88%. Disease models simplify reality and cannot capture all breast cancer subtypes. Advances in systemic therapies for breast cancer have not substantively reduced the relative benefits of screening but have likely reduced the absolute benefits because of their positive effect on breast cancer survival. University of Washington and National Cancer Institute.

  6. Turbulence modeling with fractional derivatives: Derivation from first principles and initial results

    Science.gov (United States)

    Epps, Brenden; Cushman-Roisin, Benoit

    2017-11-01

    Fluid turbulence is an outstanding unsolved problem in classical physics, despite 120+ years of sustained effort. Given this history, we assert that a new mathematical framework is needed to make a transformative breakthrough. This talk offers one such framework, based upon kinetic theory tied to the statistics of turbulent transport. Starting from the Boltzmann equation and ``Lévy α-stable distributions'', we derive a turbulence model that expresses the turbulent stresses in the form of a fractional derivative, where the fractional order is tied to the transport behavior of the flow. Initial results are presented herein, for the cases of Couette-Poiseuille flow and 2D boundary layers. Among other results, our model is able to reproduce the logarithmic Law of the Wall in shear turbulence.

  7. Comparison of pellet acceleration model results to experimentally observed penetration depths

    Energy Technology Data Exchange (ETDEWEB)

    Szepesi, T., E-mail: szepesi.tamas@gmail.co [KFKI - Research Institute for Particle and Nuclear Physics, EURATOM Association, MTA KFKI-RMKI, P.O. Box 49, H-1525 Budapest-114 (Hungary); Kalvin, S.; Kocsis, G. [KFKI - Research Institute for Particle and Nuclear Physics, EURATOM Association, MTA KFKI-RMKI, P.O. Box 49, H-1525 Budapest-114 (Hungary); Lang, P.T. [Max-Planck-Institut fuer Plasmaphysik, EURATOM Association, Boltzmannstr. 2, 85748 Garching (Germany); Senichenkov, I. [Saint Petersburg State Polytechnical University, Polytehnicheskaya 29, 195251 St. Petersburg (Russian Federation)

    2009-06-15

    Cryogenic hydrogen isotope fuelling pellets were observed to undergo strong radial acceleration in the confined plasma. The reason for pellet acceleration is believed to originate from drift effects: the ionised part of pellet cloud is affected by the grad-B drift, therefore, the cloud becomes polarised. The E x B drift then deforms the pellet cloud so that it can no longer follow the original flux bundle - this results in a less efficient shielding on the pellet's HFS region, where the subsequently enhanced ablation pushes the pellet towards LFS, like a rocket. In order to study this effect, a simple and a comprehensive ablation model was developed. Results from both models show quantitatively acceptable agreement with ASDEX-Upgrade experiments concerning trajectory curvature, corresponding to radial acceleration in the range of 10{sup 4}-10{sup 7} m/s{sup 2}.

  8. Lead/acid batteries for photovoltaic applications. Test results and modelling

    Energy Technology Data Exchange (ETDEWEB)

    Copetti, J B [CIEMAT, Inst. de Energias Renovables, Madrid (Spain); Chenlo, F [CIEMAT, Inst. de Energias Renovables, Madrid (Spain)

    1994-01-01

    This work presents the results of experiments carried out on lead/acid batteries during charge and discharge processes at different currents and temperatures, selected to a cover a large range of operating conditions, including those encountered in photovoltaic (PV) system applications. The results allow us to verify the relations among the battery external parameters (voltage, current, state-of-charge and temperature), the behaviour of the internal resistance, and to deduce a model that represents the discharge and charge processes, including the overcharge. Finally, normalized equations with respect to the battery capacity are proposed, which allow us to fix the values of parameters and hence the model is valid for any type and size of lead/acid battery. (orig.)

  9. Non-SUSY Beyond Standard Model Searches: Recent Results from ATLAS and CMS

    International Nuclear Information System (INIS)

    Malek, Fairouz

    2015-01-01

    The Standard Model of particle physics is a sensational success, especially since the discovery of the 125 GeV Higgs boson. However, there are still numerous unanswered questions. Why is the Higgs so light? Do the interactions couplings unify and how can gravity be included? Why three fermion generations? What is dark matter? Theories Beyond the Standard Model (BSM), such as Grand Unified Theories, Extra Dimensions or Technicolour are trying to answer these questions. In these proceedings, we will focus on the most recent results obtained by the ATLAS and CMS experiments at the LHC for BSM searches, excluding Higgs and supersymmetry searches. New results on Dark Matter, heavy narrow-width resonances, new heavy quarks and third generation leptoquarks are presented. A summary of the prospects at 14 TeV and at the High Luminosity LHC period is given. (paper)

  10. Non-SUSY Beyond Standard Model Searches: Recent Results from ATLAS and CMS

    CERN Document Server

    Malek, Fairouz; The ATLAS collaboration

    2015-01-01

    The Standard Model of particle physics is a sensational success, especially since the discovery of the 125 GeV Higgs boson. However, there are still numerous unanswered questions. Why is the Higgs so light? Do the interactions couplings unify and how can gravity be included? Why three fermion generations? What is dark matter? Theories Beyond the Standard Model (BSM), such as Grand Unified Theories, Extra Dimensions or Technicolour are trying to answer these questions. In this proceedings, we will focus on the most recent results obtained by the ATLAS and CMS experiments at the LHC for BSM searches, excluding Higgs and supersymmetry searches. New results on Dark matter, heavy narrow bosons, new heavy quarks and third generation leptoquarks are presented. A summary of the prospects at 14 TeV and at the High Luminosity LHC period is given.

  11. (hydronsan) in previously untreated cases of pulmo

    African Journals Online (AJOL)

    B., M.D., King George V. Hospital, Durban. SUMMARY. The results of a randomized, single-blind, between-paTienI trial of various combinations of rifampicin, .... clearing after 16 weeks of trial is higher in the rifampicin- treated groups than in the ethambutol-plus-Hydronsan group. Table III shows the radiological clearing.

  12. Deep Learning Based Solar Flare Forecasting Model. I. Results for Line-of-sight Magnetograms

    Science.gov (United States)

    Huang, Xin; Wang, Huaning; Xu, Long; Liu, Jinfu; Li, Rong; Dai, Xinghua

    2018-03-01

    Solar flares originate from the release of the energy stored in the magnetic field of solar active regions, the triggering mechanism for these flares, however, remains unknown. For this reason, the conventional solar flare forecast is essentially based on the statistic relationship between solar flares and measures extracted from observational data. In the current work, the deep learning method is applied to set up the solar flare forecasting model, in which forecasting patterns can be learned from line-of-sight magnetograms of solar active regions. In order to obtain a large amount of observational data to train the forecasting model and test its performance, a data set is created from line-of-sight magnetogarms of active regions observed by SOHO/MDI and SDO/HMI from 1996 April to 2015 October and corresponding soft X-ray solar flares observed by GOES. The testing results of the forecasting model indicate that (1) the forecasting patterns can be automatically reached with the MDI data and they can also be applied to the HMI data; furthermore, these forecasting patterns are robust to the noise in the observational data; (2) the performance of the deep learning forecasting model is not sensitive to the given forecasting periods (6, 12, 24, or 48 hr); (3) the performance of the proposed forecasting model is comparable to that of the state-of-the-art flare forecasting models, even if the duration of the total magnetograms continuously spans 19.5 years. Case analyses demonstrate that the deep learning based solar flare forecasting model pays attention to areas with the magnetic polarity-inversion line or the strong magnetic field in magnetograms of active regions.

  13. GREET 1.5 - transportation fuel-cycle model - Vol. 1 : methodology, development, use, and results

    International Nuclear Information System (INIS)

    Wang, M. Q.

    1999-01-01

    This report documents the development and use of the most recent version (Version 1.5) of the Greenhouse Gases, Regulated Emissions, and Energy Use in Transportation (GREET) model. The model, developed in a spreadsheet format, estimates the full fuel-cycle emissions and energy associated with various transportation fuels and advanced vehicle technologies for light-duty vehicles. The model calculates fuel-cycle emissions of five criteria pollutants (volatile organic compounds, carbon monoxide, nitrogen oxides, particulate matter with diameters of 10 micrometers or less, and sulfur oxides) and three greenhouse gases (carbon dioxide, methane, and nitrous oxide). The model also calculates total energy consumption, fossil fuel consumption, and petroleum consumption when various transportation fuels are used. The GREET model includes the following cycles: petroleum to conventional gasoline, reformulated gasoline, conventional diesel, reformulated diesel, liquefied petroleum gas, and electricity via residual oil; natural gas to compressed natural gas, liquefied natural gas, liquefied petroleum gas, methanol, Fischer-Tropsch diesel, dimethyl ether, hydrogen, and electricity; coal to electricity; uranium to electricity; renewable energy (hydropower, solar energy, and wind) to electricity; corn, woody biomass, and herbaceous biomass to ethanol; soybeans to biodiesel; flared gas to methanol, dimethyl ether, and Fischer-Tropsch diesel; and landfill gases to methanol. This report also presents the results of the analysis of fuel-cycle energy use and emissions associated with alternative transportation fuels and advanced vehicle technologies to be applied to passenger cars and light-duty trucks

  14. Compilation of publication and results from project C2: Modelling of microclimates in collectors

    Energy Technology Data Exchange (ETDEWEB)

    Holck, O. [ed.

    1999-08-01

    It is important to avoid condensation in solar collectors, most of all because wetness of the absorber can damage the selective surface and cause corrosion on the absorber plate. During night time the cover of collectors will cool below ambient temperature due to thermal radiation to the cold sky. In climates where the air during night time becomes saturated with humidity (the relative humidity is 100%), condensation will form on the outside and inside of the collector glazing. If too much condensation takes place on the inside of the glazing, it will start to fall off on to the absorber surface. The intent of the present work is improvement of a existing computer model for calculation of microclimates data in collectors. Calculations with the model give insight in the humidity and temperature for artificial or realistic climatic data. This design tool makes it possible to calculate the effect of ventilation and insulation materials. Results from investigation of ventilation rates together with a model of the moisture inside the collector are built into the computer program. It has been found that modelling of the moisture transfer in backside insulation is essential to determine the humidity in the air gap of the collector. The objective is to develop guidelines for solar collector design to achieve the most favourable microclimates condition for materials. As a tool the computer model will be useful to fulfil this. Guidelines for collectors will be essential for manufactures to improve the long-term durability of solar collectors. (au)

  15. Verification of simulation model with COBRA-IIIP code by confrontment of experimental results

    International Nuclear Information System (INIS)

    Silva Galetti, M.R. da; Pontedeiro, A.C.; Oliveira Barroso, A.C. de

    1985-01-01

    It is presented an evaluation of the COBRA IIIP/MIT code (of thermal hydraulic analysis by subchannels), comparing their results with experimental data obtained in stationary and transient regimes. It was done a study to calculate the spatial and temporal critical heat flux. It is presented a sensitivity study of simulation model related to the turbulent mixture and the number of axial intervals. (M.C.K.) [pt

  16. Some results of model calculations of the solar S-component radio emission

    International Nuclear Information System (INIS)

    Krueger, A.; Hildebrandt, J.

    1985-01-01

    Numerical calculations of special characteristics of the solar S-component microwave radiation are presented on the basis of recent sunspot and plage models. Quantitative results are discussed and can be used for the plasma diagnostics of solar active regions by comparisons with observations with high spatial and spectral resolution. The possibility of generalized applications to magnetic stars and stellar activity is briefly noted. (author)

  17. Fuel models and results from the TRAC-PF1/MIMAS TMI-2 accident calculation

    International Nuclear Information System (INIS)

    Schwegler, E.C.; Maudlin, P.J.

    1983-01-01

    A brief description of several fuel models used in the TRAC-PF1/MIMAS analysis of the TMI-2 accident is presented, and some of the significant fuel-rod behavior results from this analysis are given. Peak fuel-rod temperatures, oxidation heat production, and embrittlement and failure behavior calculated for the TMI-2 accident are discussed. Other aspects of fuel behavior, such as cladding ballooning and fuel-cladding eutectic formation, were found not to significantly affect the accident progression

  18. Carbon dioxide /V2/ radiance results using a new nonequilibrium model

    Science.gov (United States)

    Sharma, R. D.; Nadile, R. M.

    1981-01-01

    It was observed during the SPIRE experiment (Spectral Infrared Rocket Experiment) that the 15 micron limb radiance stays constant from 95 to 110 km despite the fact that CO2 concentration over this altitude range decreases by a factor of 20. The results of a 15 micron CO2 radiance model are presented which explain the observed anomaly. It is shown that CO2 deactivation by oxygen is the predominant factor in 15 micron emission above 95 km.

  19. Analytical results for entanglement in the five-qubit anisotropic Heisenberg model

    International Nuclear Information System (INIS)

    Wang Xiaoguang

    2004-01-01

    We solve the eigenvalue problem of the five-qubit anisotropic Heisenberg model, without use of Bethe's ansatz, and give analytical results for entanglement and mixedness of two nearest-neighbor qubits. The entanglement takes its maximum at Δ=1 (Δ>1) for the case of zero (finite) temperature with Δ being the anisotropic parameter. In contrast, the mixedness takes its minimum at Δ=1 (Δ>1) for the case of zero (finite) temperature

  20. [Prevalence of previously diagnosed diabetes mellitus in Mexico.

    Science.gov (United States)

    Rojas-Martínez, Rosalba; Basto-Abreu, Ana; Aguilar-Salinas, Carlos A; Zárate-Rojas, Emiliano; Villalpando, Salvador; Barrientos-Gutiérrez, Tonatiuh

    2018-01-01

    To compare the prevalence of previously diagnosed diabetes in 2016 with previous national surveys and to describe treatment and its complications. Mexico's national surveys Ensa 2000, Ensanut 2006, 2012 and 2016 were used. For 2016, logistic regression models and measures of central tendency and dispersion were obtained. The prevalence of previously diagnosed diabetes in 2016 was 9.4%. The increase of 2.2% relative to 2012 was not significant and only observed in patients older than 60 years. While preventive measures have increased, the access to medical treatment and lifestyle has not changed. The treatment has been modified, with an increase in insulin and decrease in hypoglycaemic agents. Population aging, lack of screening actions and the increase in diabetes complications will lead to an increase on the burden of disease. Policy measures targeting primary and secondary prevention of diabetes are crucial.

  1. Results of heater induced quenches on a 1-m SSC model dipole

    International Nuclear Information System (INIS)

    Hassenzahl, W.V.

    1985-10-01

    This report describes the results of a series of heater induced quenches on the 1-m long SSC model dipole D-12C-7 constructed at LBL. Test results of the following types are described: quench propagation velocities - axial; quench propagation velocities - transverse; and rate of temperature rise in the conductor. The primary purpose of these tests was to measure quench velocities at a variety of locations and for several currents/fields which can be used to refine the quench predictions for longer magnets. Because of limited data in the low field region of this magnet, it is recommended that it be retested with additional voltage taps. 20 figs., 6 tabs

  2. Comprehensive Interpretation of the Laboratory Experiments Results to Construct Model of the Polish Shale Gas Rocks

    Science.gov (United States)

    Jarzyna, Jadwiga A.; Krakowska, Paulina I.; Puskarczyk, Edyta; Wawrzyniak-Guz, Kamila; Zych, Marcin

    2018-03-01

    More than 70 rock samples from so-called sweet spots, i.e. the Ordovician Sa Formation and Silurian Ja Member of Pa Formation from the Baltic Basin (North Poland) were examined in the laboratory to determine bulk and grain density, total and effective/dynamic porosity, absolute permeability, pore diameters size, total surface area, and natural radioactivity. Results of the pyrolysis, i.e., TOC (Total Organic Carbon) together with S1 and S2 - parameters used to determine the hydrocarbon generation potential of rocks, were also considered. Elemental composition from chemical analyses and mineral composition from XRD measurements were also included. SCAL analysis, NMR experiments, Pressure Decay Permeability measurements together with water immersion porosimetry and adsorption/ desorption of nitrogen vapors method were carried out along with the comprehensive interpretation of the outcomes. Simple and multiple linear statistical regressions were used to recognize mutual relationships between parameters. Observed correlations and in some cases big dispersion of data and discrepancies in the property values obtained from different methods were the basis for building shale gas rock model for well logging interpretation. The model was verified by the result of the Monte Carlo modelling of spectral neutron-gamma log response in comparison with GEM log results.

  3. Vulnerability of hydropower generation to climate change in China: Results based on Grey forecasting model

    International Nuclear Information System (INIS)

    Wang, Bing; Liang, Xiao-Jie; Zhang, Hao; Wang, Lu; Wei, Yi-Ming

    2014-01-01

    This paper analyzes the long-term relationships between hydropower generation and climate factors (precipitation), hydropower generation capacity (installed capacity of hydropower station) to quantify the vulnerability of renewable energy production in China for the case of hydropower generation. Furthermore, this study applies Grey forecasting model to forecast precipitation in different provinces, and then sets up different scenarios for precipitation based on the IPCC Special Report on Emission Scenarios and results from PRECIS (Providing Regional Climate projections for Impacts Studies) model. The most important result found in this research is the increasing hydropower vulnerability of the poorest regions and the main hydropower generation provinces of China to climate change. Other main empirical results reveal that the impacts of climate change on the supply of hydropower generation in China will be noteworthy for the society. Different scenarios have different effects on hydropower generation, of which A2 scenario (pessimistic, high emission) has the largest. Meanwhile, the impacts of climate change on hydropower generation of every province are distinctly different, of which the Southwest part has the higher vulnerability than the average level while the central part lower. - Highlights: • The hydropower vulnerability will be enlarged with the rapid increase of hydropower capacity. • Modeling the vulnerability of hydropower in different scenarios and different provinces. • The increasing hydropower vulnerability of the poorest regions to climate change. • The increasing hydropower vulnerability of the main hydropower generation provinces. • Rainfall pattern caused by climate change would be the reason for the increasing vulnerability

  4. Lessons from wet gas flow metering systems using differential measurements devices: Testing and flow modelling results

    Energy Technology Data Exchange (ETDEWEB)

    Cazin, J.; Couput, J.P.; Dudezert, C. et al

    2005-07-01

    A significant number of wet gas meters used for high GVF and very high GVF are based on differential pressure measurements. Recent high pressure tests performed on a variety of different DP devices on different flow loops are presented. Application of existing correlations is discussed for several DP devices including Venturi meters. For Venturi meters, deviations vary from 9% when using the Murdock correlation to less than 3 % with physical based models. The use of DP system in a large domain of conditions (Water Liquid Ratio) especially for liquid estimation will require information on the WLR This obviously raises the question of the gas and liquid flow metering accuracy in wet gas meters and highlight needs to understand AP systems behaviour in wet gas flows (annular / mist / annular mist). As an example, experimental results obtained on the influence of liquid film characteristics on a Venturi meter are presented. Visualizations of the film upstream and inside the Venturi meter are shown. They are completed by film characterization. The AP measurements indicate that for a same Lockhart Martinelli parameter, the characteristics of the two phase flow have a major influence on the correlation coefficient. A 1D model is defined and the results are compared with the experiments. These results indicate that the flow regime influences the AP measurements and that a better modelling of the flow phenomena is needed even for allocation purposes. Based on that, lessons and way forward in wet gas metering systems improvement for allocation and well metering are discussed and proposed. (author) (tk)

  5. Mercury Studies around the Mediterranean Sea Basin: Ten years of Measurements and Modeling results

    Directory of Open Access Journals (Sweden)

    Sprovieri F.

    2013-04-01

    Full Text Available Only a few years ago the presence of Reactive Gaseous Mercury (RGM was believed to be almost exclusively the result of anthropogenic emissions and that sustained high RGM concentrations in the MBL were not considered likely. During the past ten years, an in-depth investigation was carried out in the Marine Boundary Layer (MBL of the Mediterranean Sea to quantify and possibly explain spatial and temporal patterns of Hg-species concentrations. This paper provides an overview of modeling results and atmospheric measurements performed during several cruise campaigns performed aboard the Research Vessel (RV URANIA of the CNR over the Mediterranean sea basin. RGM concentrations have been modelled using a photochemical box model of the MBL and compared to measured data obtained during the research cruises. The comparison results supports the hypothesis that there are daytime mercury oxidation reactions occurring which have not yet been identified. Major findings of key studies carried out during ten years of ship-borne activities have been highlighted.

  6. Gamma spectroscopy modelization intercomparison of the modelization results using two different codes (MCNP, and Pascalys-mercure)

    International Nuclear Information System (INIS)

    Luneville, L.; Chiron, M.; Toubon, H.; Dogny, S.; Huver, M.; Berger, L.

    2001-01-01

    The research performed in common these last 3 years by the French Atomic Commission CEA, COGEMA and Eurisys Mesures had for main subject the realization of a complete tool of modelization for the largest range of realistic cases, the Pascalys modelization software. The main purpose of the modelization was to calculate the global measurement efficiency, which delivers the most accurate relationship between the photons emitted by the nuclear source in volume, punctual or deposited form and the germanium hyper pure detector, which detects and analyzes the received photons. It has been stated since long time that experimental global measurement efficiency becomes more and more difficult to address especially for complex scene as we can find in decommissioning and dismantling or in case of high activities for which the use of high activity reference sources become difficult to use for both health physics point of view and regulations. The choice of a calculation code is fundamental if accurate modelization is searched. MCNP represents the reference code but its use is long time calculation consuming and then not practicable in line on the field. Direct line-of-sight point kernel code as the French Atomic Commission 3-D analysis Mercure code can represent the practicable compromise between the most accurate MCNP reference code and the realistic performances needed in modelization. The comparison between the results of Pascalys-Mercure and MCNP code taking in account the last improvements of Mercure in the low energy range where the most important errors can occur, is presented in this paper, Mercure code being supported in line by the recent Pascalys 3-D modelization scene software. The incidence of the intrinsic efficiency of the Germanium detector is also approached for the total efficiency of measurement. (authors)

  7. Modelling the effects of phase change materials on the energy use in buildings. Results of Experiments and System Dynamics Modelling

    Energy Technology Data Exchange (ETDEWEB)

    Prins, J.

    2012-02-15

    The current era is in need for more and more sustainable energy solutions. Phase Change Materials (PCM's) are a solution for a more sustainable build environment because they can help to reduce the energy use of buildings during heating and cooling of the indoor air. This paper presents the results of recent experiments that have been executed with test boxes. In addition a System Dynamics model has been developed to find out how PCM's can be used efficiently without testing in reality. The first experiment, in which PCM's were applied in a concrete floor, shows a reduction of peak temperatures with 4C {+-} 0.7C on maximum temperatures and over 1.5C {+-} 0.7C on minimum temperatures during warm periods. The model confirmed these findings, although the predicted reductions were slightly. During the second experiment more PCM's were applied by mounting them into the walls using gypsum plasterboard to increase the latent heat capacity. Remarkably, both the experimental set-up as the model showed that the increase of PCM's (of almost 98%) causes hardly any difference compared to the first situation. Adapting the exterior in a way to absorb more solar energy, increases the average indoor temperature but decreases the reduction of peak temperatures. Again the model confirmed these findings of the experiment. These results show that the effect of PCM's varies on different climatological contexts and with different construction components physics. This means no straight forward advice on the use of PCM's for a building design can be given. The solution for this problem is provided by the model, showing that the effects of PCM's can be modelled in order to use PCM's in an effective way in different climatological contexts and with different characteristics of construction components. The research shows that a simple model is already capable of predicting PCM performance in test boxes with reasonable accuracy. Therefore it can be

  8. Discrete Element Modeling Results of Proppant Rearrangement in the Cooke Conductivity Cell

    Energy Technology Data Exchange (ETDEWEB)

    Earl Mattson; Hai Huang; Michael Conway; Lisa O' Connell

    2014-02-01

    The study of propped fracture conductivity began in earnest with the development of the Cooke cell which later became part of the initial API standard. Subsequent developments included a patented multicell design to conduct 4 tests in a press at the same time. Other modifications have been used by various investigators. Recent studies by the Stim-Lab proppant consortium have indicated that the flow field across a Cooke proppant conductivity testing cell may not be uniform as initially believed which resulted is significantly different conductivity results. Post test analysis of low temperature metal alloy injections at the termination of proppant testing prior to the release of the applied stress suggest that higher flow is to be expected along the sides and top of the proppant pack than compared to the middle of the pack. To evaluate these experimental findings, a physics-based two-dimensional (2-D) discrete element model (DEM) was developed and applied to simulate proppant rearrangement during stress loading in the Cooke conductivity cell and the resulting porosity field. Analysis of these simulations are critical to understanding the impact of modification to the testing cell as well as understanding key proppant conductivity issues such as how these effects are manifested in proppant concentration testing results. The 2-D DEM model was constructed to represent a realistic cross section of the Cooke cell with a distribution of four material properties, three that represented the Cooke cell (steel, sandstone,square rings), and one representing the proppant. In principle, Cooke cell materials can be approximated as assemblies of independent discrete elements (particles) of various sizes and material properties that interact via cohesive interactions, repulsive forces, and frictional forces. The macroscopic behavior can then be modeled as the collective behavior of many interacting discrete elements. This DEM model is particularly suitable for modeling proppant

  9. Health and budget impact of combined HIV prevention - first results of the BELHIVPREV model.

    Science.gov (United States)

    Vermeersch, Sebastian; Callens, Steven; De Wit, Stéphane; Goffard, Jean-Christophe; Laga, Marie; Van Beckhoven, Dominique; Annemans, Lieven

    2018-02-01

    We developed a pragmatic modelling approach to estimate the impact of treatment as prevention (TasP); outreach testing strategies; and pre-exposure prophylaxis (PrEP) on the epidemiology of HIV and its associated pharmaceutical expenses. Our model estimates the incremental health (in terms of new HIV diagnoses) and budget impact of two prevention scenarios (outreach+TasP and outreach+TasP+PrEP) against a 'no additional prevention' scenario. Model parameters were estimated from reported Belgian epidemiology and literature data. The analysis was performed from a healthcare payer perspective with a 15-year-time horizon. It considers subpopulation differences, HIV infections diagnosed in Belgium having occurred prior to migration, and the effects of an ageing HIV population. Without additional prevention measures, the annual number of new HIV diagnoses rises to over 1350 new diagnoses in 2030 as compared to baseline, resulting in a budget expenditure of €260.5 million. Implementation of outreach+TasP and outreach+TasP+PrEP results in a decrease in the number of new HIV diagnoses to 865 and 663 per year, respectively. Respective budget impacts decrease by €20.6 million and €33.7 million. Foregoing additional investments in prevention is not an option. An approach combining TasP, outreach and PrEP is most effective in reducing the number of new HIV diagnoses and the HIV treatment budget. Our model is the first pragmatic HIV model in Belgium estimating the consequences of a combined preventive approach on the HIV epidemiology and its economic burden assuming other prevention efforts such as condom use and harm reduction strategies remain the same.

  10. A Mathematical Model for Reactions During Top-Blowing in the AOD Process: Validation and Results

    Science.gov (United States)

    Visuri, Ville-Valtteri; Järvinen, Mika; Kärnä, Aki; Sulasalmi, Petri; Heikkinen, Eetu-Pekka; Kupari, Pentti; Fabritius, Timo

    2017-06-01

    In earlier work, a fundamental mathematical model was proposed for side-blowing operation in the argon oxygen decarburization (AOD) process. In the preceding part "Derivation of the Model," a new mathematical model was proposed for reactions during top-blowing in the AOD process. In this model it was assumed that reactions occur simultaneously at the surface of the cavity caused by the gas jet and at the surface of the metal droplets ejected from the metal bath. This paper presents validation and preliminary results with twelve industrial heats. In the studied heats, the last combined-blowing stage was altered so that oxygen was introduced from the top lance only. Four heats were conducted using an oxygen-nitrogen mixture (1:1), while eight heats were conducted with pure oxygen. Simultaneously, nitrogen or argon gas was blown via tuyères in order to provide mixing that is comparable to regular practice. The measured carbon content varied from 0.4 to 0.5 wt pct before the studied stage to 0.1 to 0.2 wt pct after the studied stage. The results suggest that the model is capable of predicting changes in metal bath composition and temperature with a reasonably high degree of accuracy. The calculations indicate that the top slag may supply oxygen for decarburization during top-blowing. Furthermore, it is postulated that the metal droplets generated by the shear stress of top-blowing create a large mass exchange area, which plays an important role in enabling the high decarburization rates observed during top-blowing in the AOD process. The overall rate of decarburization attributable to top-blowing in the last combined-blowing stage was found to be limited by the mass transfer of dissolved carbon.

  11. Tracer simulation using a global general circulation model: Results from a midlatitude instantaneous source experiment

    International Nuclear Information System (INIS)

    Mahlman, J.D.; Moxim, W.J.

    1978-01-01

    An 11-level general circulation model with seasonal variation is used to perform an experiment on the dispersion of passive tracers. Specially constructed time-dependent winds from this model are used as input to a separate tracer model. The methodologies employed to construct the tracer model are described.The experiment presented is the evolution of a hypothetical instantaneous source of tracer on 1 Janaury with maximum initial concentration at 65 mb, 36 0 N, 180 0 E. The tracer is assumed to have no sources or sinks in the stratosphere, but is subject to removal processes in the lower troposphere.The experimental results reveal a number of similarities to observed tracer behavior, including the average poleward-downward slope of mixing ratio isopleths, strong tracer gradients across the tropopause, intrusion of tracer into the Southern Hemisphere lower stratosphere, and the long-term interhemispheric exchange rate. The model residence times show behavior intermediate to those exhibited for particulate radioactive debris and gaseous C 14 O 2 . This suggests that caution should be employed when either radioactive debris or C 14 O 2 data are used to develop empirical models for prediction of gaseous tracers which are efficiently removed in the troposphere.In this experiment, the tracer mixing ratio and potential vorticity evolve to very high correlations. Mechanisms for this correlation are discussed. The zonal mean tracer balances exhibit complex behavior among the various transport terms. At early stages, the tracer evolution is dominated by eddy effects. Later, a very large degree of self-cancellation between mean cell and eddy effects is observed. During seasonal transitions, however, this self-cancellation diminishes markedly, leading to significant changes in the zonal mean tracer distribution. A possible theoretical explanation is presented

  12. U.S. Department of Energy Reference Model Program RM1: Experimental Results

    Energy Technology Data Exchange (ETDEWEB)

    Hill, Craig [Univ. of Minnesota, Minneapolis, MN (United States); Neary, Vincent Sinclair [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gunawan, Budi [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Guala, Michele [Univ. of Minnesota, Minneapolis, MN (United States); Sotiropoulos, Fotis [Univ. of Minnesota, Minneapolis, MN (United States)

    2014-10-01

    The Reference Model Project (RMP), sponsored by the U.S. Department of Energy’s (DOE) Wind and Water Power Technologies Program within the Office of Energy Efficiency & Renewable Energy (EERE), aims at expediting industry growth and efficiency by providing non-proprietary Reference Models (RM) of MHK technology designs as study objects for open-source research and development (Neary et al. 2014a,b). As part of this program, MHK turbine models were tested in a large open channel facility at the University of Minnesota’s St. Anthony Falls Laboratory (UMN-SAFL). Reference Model 1 (RM2) is a 1:40 geometric scale dual-rotor axial flow horizontal axis device with counter-rotating rotors, each with a rotor diameter dT = 0.5m. Precise blade angular position and torque measurements were synchronized with three acoustic Doppler velocimeters (ADVs) aligned with each rotor and the midpoint for RM1. Flow conditions for each case were controlled such that depth, h = 1m, and volumetric flow rate, Qw = 2.425m3s-1, resulting in a hub height velocity of approximately Uhub = 1.05ms-1 and blade chord length Reynolds numbers of Rec ≈ 3.0x105. Vertical velocity profiles collected in the wake of each device from 1 to 10 rotor diameters are used to estimate the velocity recovery and turbulent characteristics in the wake, as well as the interaction of the counter-rotating rotor wakes. The development of this high resolution laboratory investigation provides a robust dataset that enables assessing turbulence performance models and their ability to accurately predict device performance metrics, including computational fluid dynamics (CFD) models that can be used to predict turbulent inflow environments, reproduce wake velocity deficit, recovery and higher order turbulent statistics, as well as device performance metrics.

  13. U.S. Department of Energy Reference Model Program RM1: Experimental Results.

    Energy Technology Data Exchange (ETDEWEB)

    Hill, Craig [Univ. of Minnesota, Minneapolis, MN (United States); Neary, Vincent Sinclair [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gunawan, Budi [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Guala, Michele [Univ. of Minnesota, Minneapolis, MN (United States); Sotiropoulos, Fotis [Univ. of Minnesota, Minneapolis, MN (United States)

    2017-08-01

    The Reference Model Project (RMP), sponsored by the U.S. Department of Energy’s (DOE) Wind and Water Power Technologies Program within the Office of Energy Efficiency & Renewable Energy (EERE), aims at expediting industry growth and efficiency by providing nonproprietary Reference Models (RM) of MHK technology designs as study objects for opensource research and development (Neary et al. 2014a,b). As part of this program, MHK turbine models were tested in a large open channel facility at the University of Minnesota’s St. Anthony Falls Laboratory (UMN-SAFL). Reference Model 1 (RM1) is a 1:40 geometric scale dual-rotor axial flow horizontal axis device with counter-rotating rotors, each with a rotor diameter dT = 0.5m. Precise blade angular position and torque measurements were synchronized with three acoustic Doppler velocimeters (ADVs) aligned with each rotor and the midpoint for RM1. Flow conditions for each case were controlled such that depth, h = 1m, and volumetric flow rate, Qw = 2.425m3s-1, resulting in a hub height velocity of approximately Uhub = 1.05ms-1 and blade chord length Reynolds numbers of Rec ≈ 3.0x105. Vertical velocity profiles collected in the wake of each device from 1 to 10 rotor diameters are used to estimate the velocity recovery and turbulent characteristics in the wake, as well as the interaction of the counter-rotating rotor wakes. The development of this high resolution laboratory investigation provides a robust dataset that enables assessing turbulence performance models and their ability to accurately predict device performance metrics, including computational fluid dynamics (CFD) models that can be used to predict turbulent inflow environments, reproduce wake velocity deficit, recovery and higher order turbulent statistics, as well as device performance metrics.

  14. The Formation of the Model of Diagnosing the Results Implementation of of Consulting Projects for Enterprises

    Directory of Open Access Journals (Sweden)

    Kuzmin Oleh Ye.

    2017-11-01

    Full Text Available In the article the graphic-analytical model of diagnostics of results of implementation of consulting projects is formed, which allows to: take into consideration interests of participants to the project on choice of methods and methodologies of diagnosing; allocate alternative sets of business indicators for each object of impact in terms of consulting project; establish economic and non-economic criteria for evaluating the effectiveness of consulting, as well as monitoring of indicators and automated processing of diagnostic results to control deviations from the optimal values of the diagnosed project results. A structural-logical model of formation of alternative sets of indicators and choice of indicators for diagnostics of results of consulting projects has been developed. The elements of the enterprise management system have been codified to harmonize the corresponding indicators with their subsequent combination within the proposed sets. The control system objects and their elements have been allocated. The groups of indicators according to the technology of Balanced Score Card (BSC have been presented. The prospect of further research is the economic assessment of implementation of the diagnosed consulting projects, which will reveal the links between the parameters of production-economic activity and the assessment of projects, and allows choose the most significant ones.

  15. QCD thermodynamics from an imaginary μB: Results on the four flavor lattice model

    International Nuclear Information System (INIS)

    D'Elia, Massimo; Lombardo, Maria-Paola

    2004-01-01

    We study four flavor QCD at nonzero temperature and density by analytic continuation from an imaginary chemical potential. The explored region is T=0.95T c c , and the baryochemical potentials range from 0 to ≅500 MeV. Observables include the number density, the order parameter for chiral symmetry, and the pressure, which is calculated via an integral method at fixed temperature and quark mass. The simulations are carried out on a 16 3 x4 lattice, and the mass dependence of the results is estimated by exploiting the Maxwell relations. In the hadronic region, we confirm that the results are consistent with a simple resonance hadron gas model, and we estimate the critical density by combining the results for the number density with those for the critical line. In the hot phase, above the end point of the Roberge-Weiss transition T E ≅1.1T c , the results are consistent with a free lattice model with a fixed effective number of flavor slightly different from four. We confirm that confinement and chiral symmetry are coincident by a further analysis of the critical line, and we discuss the interrelation between thermodynamics and critical behavior. We comment on the strength and weakness of the method, and propose further developments

  16. Exergy analysis of an industrial unit of catalyst regeneration based on the results of modeling and simulation

    International Nuclear Information System (INIS)

    Toghyani, Mahboubeh; Rahimi, Amir

    2015-01-01

    An industrial process is synthesized and developed for decoking of de-hydrogenation catalyst, used in LAB (Linear Alkyl Benzene) production. A multi-tube fixed bed reactor, with short length tubes is designed for decoking of catalyst as the main equipment of the process. This study provides a microscopic exergy analysis for decoking reactor and a macroscopic exergy analysis for synthesized regeneration process. The dynamic mathematical modeling technique and the simulation of process by a commercial software are applied simultaneously. The used model was previously developed for performance analysis of decoking reactor. An appropriate exergy model is developed and adopted to estimate the enthalpy, exergetic efficiency and irreversibility. The model is validated with respect to some operating data measured in a commercial regeneration unit for variations in gas and particle characteristics along the reactor. In coke-combustion period, in spite of high reaction rate, the reactor has low exergetic efficiency due to entropy production during heat and mass transfer processes. The effects of inlet gas flow rate, temperature and oxygen concentration are investigated on the exergetic efficiency and irreversibilities. Macroscopic results indicate that the fan has the highest irreversibilities among the other equipment. Applying proper operating variables reduces the cycle irreversibilities at least by 20%. - Highlights: • A microscopic exergy analysis for a multi-tube fixed bed reactor is conducted. • Controlling the O_2 concentration upgrades the reactor exergetic performance. • A macroscopic exergy analysis for synthesized regeneration process is conducted. • The fan is one of the main sources of the regeneration cycle irreversibility. • The proposed strategies can reduce the cycle irreversibilities at least by 20%.

  17. Depression storage and infiltration effects on overland flow depth-velocity-friction at desert conditions: field plot results and model

    Directory of Open Access Journals (Sweden)

    M. J. Rossi

    2012-09-01

    Full Text Available Water infiltration and overland flow are relevant in considering water partition among plant life forms, the sustainability of vegetation and the design of sustainable hydrological models and management. In arid and semi-arid regions, these processes present characteristic trends imposed by the prevailing physical conditions of the upper soil as evolved under water-limited climate. A set of plot-scale field experiments at the semi-arid Patagonian Monte (Argentina were performed in order to estimate the effect of depression storage areas and infiltration rates on depths, velocities and friction of overland flows. The micro-relief of undisturbed field plots was characterized at z-scale 1 mm through close-range stereo-photogrammetry and geo-statistical tools. The overland flow areas produced by controlled water inflows were video-recorded and the flow velocities were measured with image processing software. Antecedent and post-inflow moisture were measured, and texture, bulk density and physical properties of the upper soil were estimated based on soil core analyses. Field data were used to calibrate a physically-based, mass balanced, time explicit model of infiltration and overland flows. Modelling results reproduced the time series of observed flow areas, velocities and infiltration depths. Estimates of hydrodynamic parameters of overland flow (Reynolds-Froude numbers are informed. To our knowledge, the study here presented is novel in combining several aspects that previous studies do not address simultaneously: (1 overland flow and infiltration parameters were obtained in undisturbed field conditions; (2 field measurements of overland flow movement were coupled to a detailed analysis of soil microtopography at 1 mm depth scale; (3 the effect of depression storage areas in infiltration rates and depth-velocity friction of overland flows is addressed. Relevance of the results to other similar desert areas is justified by the accompanying

  18. SEMI-ANALYTIC GALAXY EVOLUTION (SAGE): MODEL CALIBRATION AND BASIC RESULTS

    Energy Technology Data Exchange (ETDEWEB)

    Croton, Darren J.; Stevens, Adam R. H.; Tonini, Chiara; Garel, Thibault; Bernyk, Maksym; Bibiano, Antonio; Hodkinson, Luke; Mutch, Simon J.; Poole, Gregory B.; Shattow, Genevieve M. [Centre for Astrophysics and Supercomputing, Swinburne University of Technology, P.O. Box 218, Hawthorn, Victoria 3122 (Australia)

    2016-02-15

    This paper describes a new publicly available codebase for modeling galaxy formation in a cosmological context, the “Semi-Analytic Galaxy Evolution” model, or sage for short.{sup 5} sage is a significant update to the 2006 model of Croton et al. and has been rebuilt to be modular and customizable. The model will run on any N-body simulation whose trees are organized in a supported format and contain a minimum set of basic halo properties. In this work, we present the baryonic prescriptions implemented in sage to describe the formation and evolution of galaxies, and their calibration for three N-body simulations: Millennium, Bolshoi, and GiggleZ. Updated physics include the following: gas accretion, ejection due to feedback, and reincorporation via the galactic fountain; a new gas cooling–radio mode active galactic nucleus (AGN) heating cycle; AGN feedback in the quasar mode; a new treatment of gas in satellite galaxies; and galaxy mergers, disruption, and the build-up of intra-cluster stars. Throughout, we show the results of a common default parameterization on each simulation, with a focus on the local galaxy population.

  19. The European Integrated Tokamak Modelling (ITM) effort: achievements and first physics results

    International Nuclear Information System (INIS)

    Falchetto, G.L.; Nardon, E.; Artaud, J.F.; Basiuk, V.; Huynh, Ph.; Imbeaux, F.; Coster, D.; Scott, B.D.; Coelho, R.; Alves, L.L.; Bizarro, João P.S.; Ferreira, J.; Figueiredo, A.; Figini, L.; Nowak, S.; Farina, D.; Kalupin, D.; Boulbe, C.; Faugeras, B.; Dinklage, A.

    2014-01-01

    A selection of achievements and first physics results are presented of the European Integrated Tokamak Modelling Task Force (EFDA ITM-TF) simulation framework, which aims to provide a standardized platform and an integrated modelling suite of validated numerical codes for the simulation and prediction of a complete plasma discharge of an arbitrary tokamak. The framework developed by the ITM-TF, based on a generic data structure including both simulated and experimental data, allows for the development of sophisticated integrated simulations (workflows) for physics application. The equilibrium reconstruction and linear magnetohydrodynamic (MHD) stability simulation chain was applied, in particular, to the analysis of the edge MHD stability of ASDEX Upgrade type-I ELMy H-mode discharges and ITER hybrid scenario, demonstrating the stabilizing effect of an increased Shafranov shift on edge modes. Interpretive simulations of a JET hybrid discharge were performed with two electromagnetic turbulence codes within ITM infrastructure showing the signature of trapped-electron assisted ITG turbulence. A successful benchmark among five EC beam/ray-tracing codes was performed in the ITM framework for an ITER inductive scenario for different launching conditions from the equatorial and upper launcher, showing good agreement of the computed absorbed power and driven current. Selected achievements and scientific workflow applications targeting key modelling topics and physics problems are also presented, showing the current status of the ITM-TF modelling suite. (paper)

  20. Preliminary results in the application of radiobiological models in the evaluation of radiotherapy plans

    International Nuclear Information System (INIS)

    Calderon, Carlos; Napoles, Mysleidis; Asencion, Yudy; Yanes, Yahima; Alfonso, Rodolfo; Gonzalez, Joaquin

    2009-01-01

    Notwithstanding the limitations of radiobiological models in the clinical application, its use is becoming more widespread in order to quantitatively assess the bioequivalence of different regimens of irradiation, the effective comparison between different treatment plans by estimating the probability tumor control (TCP) or the probability of normal tissue complication (NTCP), or solve problems, such as the rescheduling of treatments in case of failure. The response to irradiation in the tissues at risk (OARS) depends on factors such as volume irradiated or its organizational structure and behavior can vary for a given dose distribution. Another important aspect is the sensitivity of these models to the variation of parameters (α, α / β, proliferation, clonogenic density, etc.) Measuring the difference between-subjects. Commercial planning systems do not always possible to estimate the biological response of the OARS and CTV. This study presents an assessment of the results of two applications (free ware) and Albireo Target BIOPLAN Cygnus X1 that calculate statistical parameters of the DVH: equivalent uniform dose (EUD), equivalent biological dose (BED), medium dose and other to estimate TCP (Poisson model) and NTCP (Lyman-Kutcker models-Burman and relative seriality) for the calculation of the objective functions: the probability of uncomplicated control (UTCP) based on generalized EUD (f). We studied the response of both systems to the variation of relevant radiobiological parameters and the shape of the DVH. (Author)

  1. Preliminary results in the application of radiobiological models in the evaluation of radiotherapy plans

    International Nuclear Information System (INIS)

    Calderon, Carlos; Napoles, Mysleidis; Asencion, Yudy; Yanes, Yahima; Alfonso, Rodolfo; Gonzalez Joaquin

    2009-01-01

    Notwithstanding the limitations of radiobiological models in the clinical application, its use is becoming more widespread in order to quantitatively assess the bioequivalence of different regimens of irradiation, the effective comparison between different treatment plans by estimating the probability tumor control (TCP) or the probability of normal tissue complication (NTCP), or solve problems, such as the rescheduling of treatments in case of failure. The response to irradiation in the tissues at risk (OARS) depends on factors such as volume irradiated or its organizational structure and behavior can vary for a given dose distribution. Another important aspect is the sensitivity of these models to the variation of parameters (a, a / β, proliferation, clonogenic density, etc.) Measuring the difference between-subjects. Commercial planning systems do not always possible to estimate the biological response of the OARS and CTV. This study presents an assessment of the results of two applications (free ware) and Albireo Target BIOPLAN Cygnus X1 that calculate statistical parameters of the DVH: equivalent uniform dose (EUD), equivalent biological dose (BED), medium dose and other to estimate TCP (Poisson model) and NTCP (Lyman-models-Kutcker Burman and relative seriality) for the calculation of the objective functions: the probability of uncomplicated control (UTCP) based on generalized EUD (f). We studied the response of both systems to the variation of relevant radiobiological parameters and the shape of the DVH. (author)

  2. Results from an acoustic modelling study of seismic airgun survey noise in Queen Charlotte Basin

    Energy Technology Data Exchange (ETDEWEB)

    MacGillivray, A.O.; Chapman, N.R. [Victoria Univ., BC (Canada). School of Earth and Ocean Sciences

    2005-12-07

    An acoustic modelling study was conducted to examine seismic survey noise propagation in the Queen Charlotte Basin (QCB) and better understand the physical aspects of sound transmission. The study results are intended to help determine the potential physiological and behavioural effects of airgun noise on marine mammals and fish. The scope of the study included a numerical simulation of underwater sound transmission in QCB in areas where oil and gas exploration activities may be conducted; a forecast of received noise levels by combining acoustic transmission loss computations with acoustic source levels representative of seismic exploration activity and, the use of received forecasts to estimate zones of impact for marine mammals. The critical environmental parameters in the QCB are the bathymetry of the ocean, the sound speed profile in the water and the geoacoustic profile of the seabed. The RAM acoustic propagation model developed by the United States Naval Research Laboratory was used to compute acoustic transmission loss in the QCB. The source level and directionality of the seismic array was determined by a full-waveform array source signature model. This modelling study of noise propagation from seismic surveys revealed several key findings. Among them, it showed that received noise levels in the water are affected by the source location, array orientation and the shape of the sound speed profile with respect to water depth. It also showed that noise levels are lowest in shallow bathymetry. 30 refs., 5 tabs., 13 figs.

  3. Energetic neutral atom imaging with the Polar CEPPAD/IPS instrument: Initial forward modeling results

    International Nuclear Information System (INIS)

    Henderson, M.G.; Reeves, G.D.; Moore, K.R.; Spence, H.E.; Jorgensen, A.M.; Roelof, E.C.

    1997-01-01

    Although the primary function of the CEP-PAD/IPS instrument on Polar is the measurement of energetic ions in-situ, it has also proven to be a very capable Energetic neutral Atom (ENA) imager. Raw ENA images are currently being constructed on a routine basis with a temporal resolution of minutes during both active and quiet times. However, while analyses of these images by themselves provide much information on the spatial distribution and dynamics of the energetic ion population in the ring current, detailed modeling is required to extract the actual ion distributions. In this paper, the authors present the initial results of forward modeling an IPS ENA image obtained during a small geo-magnetic storm on June 9, 1997. The equatorial ion distribution inferred with this technique reproduces the expected large noon/midnight and dawn/dusk asymmetries. The limitations of the model are discussed and a number of modifications to the basic forward modeling technique are proposed which should significantly improve its performance in future studies

  4. Biomonitoring of airborne particulate matter emitted from a cement plant and comparison with dispersion modelling results

    Science.gov (United States)

    Abril, Gabriela A.; Wannaz, Eduardo D.; Mateos, Ana C.; Pignata, María L.

    2014-01-01

    The influence of a cement plant that incinerates industrial waste on the air quality of a region in the province of Córdoba, Argentina, was assessed by means of biomonitoring studies (effects of immission) and atmospheric dispersion (effects of emission) of PM10 with the application of the ISC3 model (Industrial Source Complex) developed by the USEPA (Environmental Protection Agency). For the biomonitoring studies, samples from the epiphyte plant Tillandsia capillaris Ruíz & Pav. f. capillaris were transplanted to the vicinities of the cement plant in order to determine the physiological damage and heavy metal accumulation (Ca, Mn, Fe, Co, Ni, Cu, Zn, Cd and Pb). For the application of the ISC3 model, point and area sources from the cement plant were considered to obtain average PM10 concentration results from the biomonitoring exposure period. This model permitted it to be determined that the emissions from the cement plant (point and area sources) were confined to the vicinities, without significant dispersion in the study area. This was also observed in the biomonitoring study, which identified Ca, Cd and Pb, pH and electric conductivity (EC) as biomarkers of this cement plant. Vehicular traffic emissions and soil re-suspension could be observed in the biomonitors, giving a more complete scenario. In this study, biomonitoring studies along with the application of atmospheric dispersion models, allowed the atmospheric pollution to be assessed in more detail.

  5. Evolution in performance assessment modeling as a result of regulatory review

    Energy Technology Data Exchange (ETDEWEB)

    Rowat, J.H.; Dolinar, G.M.; Stephens, M.E. [AECL Chalk River Labs., Ontario (Canada)] [and others

    1995-12-31

    AECL is planning to build the IRUS (Intrusion Resistant Underground Structure) facility for near-surface disposal of LLRW. The PSAR (preliminary safety assessment report) was subject to an initial regulatory review during mid-1992. The regulatory authority provided comments on many aspects of the safety assessment documentation including a number of questions on specific PA (Performance Assessment) modelling assumptions. As a result of these comments as well as a separate detailed review of the IRUS disposal concept, changes were made to the conceptual and mathematical models. The original disposal concept included a non-sorbing vault backfill, with a strong reliance on the wasteform as a barrier. This concept was altered to decrease reliance on the wasteform by replacing the original backfill with a sand/clinoptilolite mix, which is a better sorber of metal cations. This change lead to changes in the PA models which in turn altered the safety case for the facility. This, and other changes that impacted performance assessment modelling are the subject of this paper.

  6. SEMI-ANALYTIC GALAXY EVOLUTION (SAGE): MODEL CALIBRATION AND BASIC RESULTS

    International Nuclear Information System (INIS)

    Croton, Darren J.; Stevens, Adam R. H.; Tonini, Chiara; Garel, Thibault; Bernyk, Maksym; Bibiano, Antonio; Hodkinson, Luke; Mutch, Simon J.; Poole, Gregory B.; Shattow, Genevieve M.

    2016-01-01

    This paper describes a new publicly available codebase for modeling galaxy formation in a cosmological context, the “Semi-Analytic Galaxy Evolution” model, or sage for short. 5 sage is a significant update to the 2006 model of Croton et al. and has been rebuilt to be modular and customizable. The model will run on any N-body simulation whose trees are organized in a supported format and contain a minimum set of basic halo properties. In this work, we present the baryonic prescriptions implemented in sage to describe the formation and evolution of galaxies, and their calibration for three N-body simulations: Millennium, Bolshoi, and GiggleZ. Updated physics include the following: gas accretion, ejection due to feedback, and reincorporation via the galactic fountain; a new gas cooling–radio mode active galactic nucleus (AGN) heating cycle; AGN feedback in the quasar mode; a new treatment of gas in satellite galaxies; and galaxy mergers, disruption, and the build-up of intra-cluster stars. Throughout, we show the results of a common default parameterization on each simulation, with a focus on the local galaxy population

  7. Noninvasive assessment of mitral inertness [correction of inertance]: clinical results with numerical model validation.

    Science.gov (United States)

    Firstenberg, M S; Greenberg, N L; Smedira, N G; McCarthy, P M; Garcia, M J; Thomas, J D

    2001-01-01

    Inertial forces (Mdv/dt) are a significant component of transmitral flow, but cannot be measured with Doppler echo. We validated a method of estimating Mdv/dt. Ten patients had a dual sensor transmitral (TM) catheter placed during cardiac surgery. Doppler and 2D echo was performed while acquiring LA and LV pressures. Mdv/dt was determined from the Bernoulli equation using Doppler velocities and TM gradients. Results were compared with numerical modeling. TM gradients (range: 1.04-14.24 mmHg) consisted of 74.0 +/- 11.0% inertial forcers (range: 0.6-12.9 mmHg). Multivariate analysis predicted Mdv/dt = -4.171(S/D (RATIO)) + 0.063(LAvolume-max) + 5. Using this equation, a strong relationship was obtained for the clinical dataset (y=0.98x - 0.045, r=0.90) and the results of numerical modeling (y=0.96x - 0.16, r=0.84). TM gradients are mainly inertial and, as validated by modeling, can be estimated with echocardiography.

  8. [Economic efficiency of renal denervation in patients with resistant hypertension: results of Markov modeling].

    Science.gov (United States)

    Kontsevaia, A V; Suvorova, E I; Khudiakov, M B

    2014-01-01

    Aim of this study was to evaluate the cost-effectiveness of renal denervation (RD) in resistant arterial hypertension (AH) in Russia. Modeling of Markov conducted economic impact of RD on the Russian population of patients with resistant hypertension in combination with optimal medical therapy (OMT) compared with OMT using a model developed by American researchers based on the results of international research. The model contains data on Russian mortality, and costs of major complications of hypertension. The simulation results showed a significant reduction in relative risk reduction of adverse outcomes in patients with resistant hypertension for 10 years (risk of stroke is reduced by 30%, myocardial infarction - 32%). RD saves 0.9 years of quality-adjusted life (QALY) by an average of 1 patient with resistant hypertension. Costs for 1 year stored in the application of quality of life amounted to RD 203 791.6 rubles. Which is below the 1 gross domestic product and therefore indicates the feasibility of this method in Russia.

  9. The interaction of genetics and environmental toxicants in amyotrophic lateral sclerosis: results from animal models

    Institute of Scientific and Technical Information of China (English)

    Roger B. Sher

    2017-01-01

    Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that results in the progres-sive death of motor neurons, leading to paralysis and eventual death. There is presently no cure for ALS, and only two drugs are available, neither of which provide significant extension of life. The wide variation in onset and progression of the disease, both in sporadic and even in strongly penetrant monogenic famil-ial forms of ALS, indicate that in addition to background genetic variation impacting the disease process, environmental exposures are likely contributors. Epidemiological evidence worldwide implicates exposures to bacterial toxins, heavy metals, pesticides, and trauma as probable environmental factors. Here, we review current advances in gene-environment interactions in ALS animal models. We report our recent discov-eries in a zebrafish model of ALS in relation to exposure to the cyanobacterial toxin BMAA, and discuss several results from mouse models that show interactions with exposure to mercury and statin drugs, both leading to acceleration of the disease process. The increasing research into this combinatorial gene-environ-ment process is just starting, but shows early promise to uncover the underlying biochemical pathways that instigate the initial motor neuron defects and lead to their rapidly progressive dysfunction.

  10. Secondary recurrent miscarriage is associated with previous male birth.

    LENUS (Irish Health Repository)

    Ooi, Poh Veh

    2012-01-31

    Secondary recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses after delivery of a viable infant. Previous reports suggest that a firstborn male child is associated with less favourable subsequent reproductive potential, possibly due to maternal immunisation against male-specific minor histocompatibility antigens. In a retrospective cohort study of 85 cases of secondary RM we aimed to determine if secondary RM was associated with (i) gender of previous child, maternal age, or duration of miscarriage history, and (ii) increased risk of pregnancy complications. Fifty-three women (62.0%; 53\\/85) gave birth to a male child prior to RM compared to 32 (38.0%; 32\\/85) who gave birth to a female child (p=0.002). The majority (91.7%; 78\\/85) had uncomplicated, term deliveries and normal birth weight neonates, with one quarter of the women previously delivered by Caesarean section. All had routine RM investigations and 19.0% (16\\/85) had an abnormal result. Fifty-seven women conceived again and 33.3% (19\\/57) miscarried, but there was no significant difference in failure rates between those with a previous male or female child (13\\/32 vs. 6\\/25, p=0.2). When patients with abnormal results were excluded, or when women with only one previous child were considered, there was still no difference in these rates. A previous male birth may be associated with an increased risk of secondary RM but numbers preclude concluding whether this increases recurrence risk. The suggested association with previous male birth provides a basis for further investigations at a molecular level.

  11. Secondary recurrent miscarriage is associated with previous male birth.

    LENUS (Irish Health Repository)

    Ooi, Poh Veh

    2011-01-01

    Secondary recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses after delivery of a viable infant. Previous reports suggest that a firstborn male child is associated with less favourable subsequent reproductive potential, possibly due to maternal immunisation against male-specific minor histocompatibility antigens. In a retrospective cohort study of 85 cases of secondary RM we aimed to determine if secondary RM was associated with (i) gender of previous child, maternal age, or duration of miscarriage history, and (ii) increased risk of pregnancy complications. Fifty-three women (62.0%; 53\\/85) gave birth to a male child prior to RM compared to 32 (38.0%; 32\\/85) who gave birth to a female child (p=0.002). The majority (91.7%; 78\\/85) had uncomplicated, term deliveries and normal birth weight neonates, with one quarter of the women previously delivered by Caesarean section. All had routine RM investigations and 19.0% (16\\/85) had an abnormal result. Fifty-seven women conceived again and 33.3% (19\\/57) miscarried, but there was no significant difference in failure rates between those with a previous male or female child (13\\/32 vs. 6\\/25, p=0.2). When patients with abnormal results were excluded, or when women with only one previous child were considered, there was still no difference in these rates. A previous male birth may be associated with an increased risk of secondary RM but numbers preclude concluding whether this increases recurrence risk. The suggested association with previous male birth provides a basis for further investigations at a molecular level.

  12. Assessing the Impact of Antidrug Advertising on Adolescent Drug Consumption: Results From a Behavioral Economic Model

    Science.gov (United States)

    Block, Lauren G.; Morwitz, Vicki G.; Putsis, William P.; Sen, Subrata K.

    2002-01-01

    Objectives. This study examined whether adolescents’ recall of antidrug advertising is associated with a decreased probability of using illicit drugs and, given drug use, a reduced volume of use. Methods. A behavioral economic model of influences on drug consumption was developed with survey data from a nationally representative sample of adolescents to determine the incremental impact of antidrug advertising. Results. The findings provided evidence that recall of antidrug advertising was associated with a lower probability of marijuana and cocaine/crack use. Recall of such advertising was not associated with the decision of how much marijuana or cocaine/crack to use. Results suggest that individuals predisposed to try marijuana are also predisposed to try cocaine/crack. Conclusions. The present results provide support for the effectiveness of antidrug advertising programs. (Am J Public Health. 2002;92:1346–1351) PMID:12144995

  13. Dissolved oxygen analysis, TMDL model comparison, and particulate matter shunting—Preliminary results from three model scenarios for the Klamath River upstream of Keno Dam, Oregon

    Science.gov (United States)

    Sullivan, Annett B.; Rounds, Stewart A.; Deas, Michael L.; Sogutlugil, I. Ertugrul

    2012-01-01

    Efforts are underway to identify actions that would improve water quality in the Link River to Keno Dam reach of the Upper Klamath River in south-central Oregon. To provide further insight into water-quality improvement options, three scenarios were developed, run, and analyzed using previously calibrated CE-QUAL-W2 hydrodynamic and water-quality models. Additional scenarios are under development as part of this ongoing study. Most of these scenarios evaluate changes relative to a "current conditions" model, but in some cases a "natural conditions" model was used that simulated the reach without the effect of point and nonpoint sources and set Upper Klamath Lake at its Total Maximum Daily Load (TMDL) targets. These scenarios were simulated using a model developed by the U.S. Geological Survey (USGS) and Watercourse Engineering, Inc. for the years 2006–09, referred to here as the "USGS model." Another model of the reach was developed by Tetra Tech, Inc. for years 2000 and 2002 to support the Klamath River TMDL process; that model is referred to here as the "TMDL model." The three scenarios described in this report included (1) an analysis of whether this reach of the Upper Klamath River would be in compliance with dissolved oxygen standards if sources met TMDL allocations, (2) an application of more recent datasets to the TMDL model with comparison to results from the USGS model, and (3) an examination of the effect on dissolved oxygen in the Klamath River if particulate material were stopped from entering Klamath Project diversion canals. Updates and modifications to the USGS model are in progress, so in the future these scenarios will be reanalyzed with the updated model and the interim results presented here will be superseded. Significant findings from this phase of the investigation include: * The TMDL analysis used depth-averaged dissolved oxygen concentrations from model output for comparison with dissolved oxygen standards. The Oregon dissolved oxygen

  14. GUIDING NONLINEAR FORCE-FREE MODELING USING CORONAL OBSERVATIONS: FIRST RESULTS USING A QUASI-GRAD-RUBIN SCHEME

    Energy Technology Data Exchange (ETDEWEB)

    Malanushenko, A. [Department of Physics, Montana State University, Bozeman, MT (United States); Schrijver, C. J.; DeRosa, M. L. [Lockheed Martin Advanced Technology Center, Palo Alto, CA (United States); Wheatland, M. S.; Gilchrist, S. A. [Sydney Institute for Astronomy, School of Physics, University of Sydney (Australia)

    2012-09-10

    At present, many models of the coronal magnetic field rely on photospheric vector magnetograms, but these data have been shown to be problematic as the sole boundary information for nonlinear force-free field extrapolations. Magnetic fields in the corona manifest themselves in high-energy images (X-rays and EUV) in the shapes of coronal loops, providing an additional constraint that is not at present used as constraints in the computational domain, directly influencing the evolution of the model. This is in part due to the mathematical complications of incorporating such input into numerical models. Projection effects, confusion due to overlapping loops (the coronal plasma is optically thin), and the limited number of usable loops further complicate the use of information from coronal images. We develop and test a new algorithm to use images of coronal loops in the modeling of the solar coronal magnetic field. We first fit projected field lines with those of constant-{alpha} force-free fields to approximate the three-dimensional distribution of currents in the corona along a sparse set of trajectories. We then apply a Grad-Rubin-like iterative technique, which uses these trajectories as volume constraints on the values of {alpha}, to obtain a volume-filling nonlinear force-free model of the magnetic field, modifying a code and method presented by Wheatland. We thoroughly test the technique on known analytical and solar-like model magnetic fields previously used for comparing different extrapolation techniques and compare the results with those obtained by currently available methods relying only on the photospheric data. We conclude that we have developed a functioning method of modeling the coronal magnetic field by combining the line-of-sight component of the photospheric magnetic field with information from coronal images. Whereas we focus on the use of coronal loop information in combination with line-of-sight magnetograms, the method is readily extended to

  15. GUIDING NONLINEAR FORCE-FREE MODELING USING CORONAL OBSERVATIONS: FIRST RESULTS USING A QUASI-GRAD-RUBIN SCHEME

    International Nuclear Information System (INIS)

    Malanushenko, A.; Schrijver, C. J.; DeRosa, M. L.; Wheatland, M. S.; Gilchrist, S. A.

    2012-01-01

    At present, many models of the coronal magnetic field rely on photospheric vector magnetograms, but these data have been shown to be problematic as the sole boundary information for nonlinear force-free field extrapolations. Magnetic fields in the corona manifest themselves in high-energy images (X-rays and EUV) in the shapes of coronal loops, providing an additional constraint that is not at present used as constraints in the computational domain, directly influencing the evolution of the model. This is in part due to the mathematical complications of incorporating such input into numerical models. Projection effects, confusion due to overlapping loops (the coronal plasma is optically thin), and the limited number of usable loops further complicate the use of information from coronal images. We develop and test a new algorithm to use images of coronal loops in the modeling of the solar coronal magnetic field. We first fit projected field lines with those of constant-α force-free fields to approximate the three-dimensional distribution of currents in the corona along a sparse set of trajectories. We then apply a Grad-Rubin-like iterative technique, which uses these trajectories as volume constraints on the values of α, to obtain a volume-filling nonlinear force-free model of the magnetic field, modifying a code and method presented by Wheatland. We thoroughly test the technique on known analytical and solar-like model magnetic fields previously used for comparing different extrapolation techniques and compare the results with those obtained by currently available methods relying only on the photospheric data. We conclude that we have developed a functioning method of modeling the coronal magnetic field by combining the line-of-sight component of the photospheric magnetic field with information from coronal images. Whereas we focus on the use of coronal loop information in combination with line-of-sight magnetograms, the method is readily extended to incorporate

  16. Measurements of entanglement over a kilometric distance to test superluminal models of Quantum Mechanics: preliminary results.

    Science.gov (United States)

    Cocciaro, B.; Faetti, S.; Fronzoni, L.

    2017-08-01

    As shown in the EPR paper (Einstein, Podolsky e Rosen, 1935), Quantum Mechanics is a non-local Theory. The Bell theorem and the successive experiments ruled out the possibility of explaining quantum correlations using only local hidden variables models. Some authors suggested that quantum correlations could be due to superluminal communications that propagate isotropically with velocity vt > c in a preferred reference frame. For finite values of vt and in some special cases, Quantum Mechanics and superluminal models lead to different predictions. So far, no deviations from the predictions of Quantum Mechanics have been detected and only lower bounds for the superluminal velocities vt have been established. Here we describe a new experiment that increases the maximum detectable superluminal velocities and we give some preliminary results.

  17. Efficiency and effects of carbon sequestration through ocean fertilization: results from a model study

    Energy Technology Data Exchange (ETDEWEB)

    Anand Gnanadesikan; Jorge L. Sarmiento; Richard D. Slater [NOAA/Geophysical Fluid Dynamics Laboratory, Princeton, NJ (United States)

    2003-07-01

    Simulations of ocean fertilization, which is patchy in space and time, were carried out using a simple model of nutrient cycling embedded in an ocean general circulation model which is integrated for 100 years. The fraction of the transient pulse of carbon produced by fertilization that comes out of the atmosphere is highly variable (ranging from 2%-44%). This fraction depends on the details of the long-term fate of the nutrients added as part of the fertilization, making verification of carbon sequestration extremely difficult. Additionally, in cases where fertilization removes nutrients from the surface layer, the result is to cause a decrease in production at subsequent times. These effects need to be taken into account when the impacts of fertilization on atmospheric carbon dioxide are evaluated. 10 refs., 1 fig., 1 tab.

  18. Tracking LHC Models with Thick Lens Quadrupoles: Results and Comparisons with the Standard Thin Lens tracking.

    CERN Document Server

    Burkhardt, H; Risselada, T

    2012-01-01

    So far, the massive numerical simulation studies of the LHC dynamic aperture were performed using thin lens models of the machine. This approach has the clear advantage of speed, but it has also the disadvantage of requiring re-matching of the optics from the real thick configuration to the thin one. The figure-of-merit for the re-matching is the agreement between the beta-functions for the two models. However, the quadrupole gradients are left as free parameters, thus, the impact of the magnetic multipoles might be affected by this approach. In turns, the dynamic aperture computation could be changed. In this paper the new approach is described and the results for the dynamic aperture are compared with the old approach, including detailed considerations on the CPU-time requirements.

  19. Field studies of submerged-diffuser thermal plumes with comparisons to predictive model results

    International Nuclear Information System (INIS)

    Frigo, A.A.; Paddock, R.A.; Ditmars, J.D.

    1976-01-01

    Thermal plumes from submerged discharges of cooling water from two power plants on Lake Michigan were studied. The system for the acquisition of water temperatures and ambient conditions permitted the three-dimensional structure of the plumes to be determined. The Zion Nuclear Power Station has two submerged discharge structures separated by only 94 m. Under conditions of flow from both structures, interaction between the two plumes resulted in larger thermal fields than would be predicted by the superposition of single non-interacting plumes. Maximum temperatures in the near-field region of the plume compared favorably with mathematical model predictions. A comparison of physical-model predictions for the plume at the D. C. Cook Nuclear Plant with prototype measurements indicated good agreement in the near-field region, but differences in the far-field occurred as similitude was not preserved there

  20. Gold Nanoparticles as Probes for Nano-Raman Spectroscopy: Preliminary Experimental Results and Modeling

    Directory of Open Access Journals (Sweden)

    V. Le Nader

    2012-01-01

    Full Text Available This paper presents an effective Tip-Enhanced Raman Spectrometer (TERS in backscattering reflection configuration. It combines a tip-probe nanopositioning system with Raman spectroscope. Specific tips were processed by anchoring gold nanoparticles on the apex of tapered optical fibers, prepared by an improved chemical etching method. Hence, it is possible to expose a very small area of the sample (~20 nm2 to the very strong local electromagnetic field generated by the lightning rod effect. This experimental configuration was modelled and optimised using the finite element method, which takes into account electromagnetic effects as well as the plasmon resonance. Finally, TERS measurements on single-wall carbon nanotubes were successfully performed. These results confirm the high Raman scattering enhancement predicted by the modelling, induced by our new nano-Raman device.

  1. Active vibration absorber for CSI evolutionary model: Design and experimental results

    Science.gov (United States)

    Bruner, Anne M.; Belvin, W. Keith; Horta, Lucas G.; Juang, Jer-Nan

    1991-01-01

    The development of control of large flexible structures technology must include practical demonstration to aid in the understanding and characterization of controlled structures in space. To support this effort, a testbed facility was developed to study practical implementation of new control technologies under realistic conditions. The design is discussed of a second order, acceleration feedback controller which acts as an active vibration absorber. This controller provides guaranteed stability margins for collocated sensor/actuator pairs in the absence of sensor/actuator dynamics and computational time delay. The primary performance objective considered is damping augmentation of the first nine structural modes. Comparison of experimental and predicted closed loop damping is presented, including test and simulation time histories for open and closed loop cases. Although the simulation and test results are not in full agreement, robustness of this design under model uncertainty is demonstrated. The basic advantage of this second order controller design is that the stability of the controller is model independent.

  2. Managing previously disposed waste to today's standards

    International Nuclear Information System (INIS)

    1990-01-01

    A Radioactive Waste Management Complex (RWMC) was established at the Idaho National Engineering Laboratory (INEL) in 1952 for controlled disposal of radioactive waste generated at the INEL. Between 1954 and 1970 waste characterized by long lived, alpha emitting radionuclides from the Rocky Flats Plant was also buried at this site. Migration of radionuclides and other hazardous substances from the buried Migration of radionuclides and other hazardous substances from the buried waste has recently been detected. A Buried Waste Program (BWP) was established to manage cleanup of the buried waste. This program has four objectives: (1) determine contaminant sources, (2) determine extent of contamination, (3) mitigate migration, and (4) recommend an alternative for long term management of the waste. Activities designed to meet these objectives have been under way since the inception of the program. The regulatory environment governing these activities is evolving. Pursuant to permitting activities under the Resource Conservation and Recovery Act (RCRA), the Department of Energy (DOE) and the Environmental Protection Agency (EPA) entered into a Consent Order Compliance Agreement (COCA) for cleanup of past practice disposal units at the INEL. Subsequent to identification of the RWMC as a release site, cleanup activities proceeded under dual regulatory coverage of RCRA and the Atomic Energy Act. DOE, EPA, and the State of Idaho are negotiating a RCRA/Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) Interagency Agreement (IAG) for management of waste disposal sites at the INEL as a result of the November 1989 listing of the INEL on the National Priority List (NPL). Decision making for selection of cleanup technology will be conducted under the CERCLA process supplemented as required to meet the requirements of the National Environmental Policy Act (NEPA). 7 figs

  3. Investigation of previously derived Hyades, Coma, and M67 reddenings

    International Nuclear Information System (INIS)

    Taylor, B.J.

    1980-01-01

    New Hyades polarimetry and field star photometry have been obtained to check the Hyades reddening, which was found to be nonzero in a previous paper. The new Hyades polarimetry implies essentially zero reddening; this is also true of polarimetry published by Behr (which was incorrectly interpreted in the previous paper). Four photometric techniques which are presumed to be insensitive to blanketing are used to compare the Hyades to nearby field stars; these four techniques also yield essentially zero reddening. When all of these results are combined with others which the author has previously published and a simultaneous solution for the Hyades, Coma, and M67 reddenings is made, the results are E (B-V) =3 +- 2 (sigma) mmag, -1 +- 3 (sigma) mmag, and 46 +- 6 (sigma) mmag, respectively. No support for a nonzero Hyades reddening is offered by the new results. When the newly obtained reddenings for the Hyades, Coma, and M67 are compared with results from techniques given by Crawford and by users of the David Dunlap Observatory photometric system, no differences between the new and other reddenings are found which are larger than about 2 sigma. The author had previously found that the M67 main-sequence stars have about the same blanketing as that of Coma and less blanketing than the Hyades; this conclusion is essentially unchanged by the revised reddenings

  4. Competency model for dentists in China: Results of a Delphi study.

    Science.gov (United States)

    Geng, Yunxia; Zhao, Liying; Wang, Yu; Jiang, Yiyuan; Meng, Kai; Zheng, Dongxiang

    2018-01-01

    With the increasing awareness of the importance of oral health, patients have an increasing need for integrated care from dentists. In China, the dentistry examination consists of two parts: a practical skills examination and a comprehensive medical examination; to date, no assessment methods that are based on specialized dentistry competencies, unlike the United States, Canada, and other countries, have been established. Therefore, the purpose of this study was to construct a competency model for dentists in China in order to guide the development, admission, training and assessment of dentists. Using a literature review, focus group interviews and in-depth personal interviews, a dentist competency index was developed with an expert consultation questionnaire. A panel of 20 specialist experts was chosen from ten national medical universities to carry out two rounds of Delphi expert analysis, using the boundary value method to filter the indicators and the Analytic Hierarchy Process to calculate the weights of the primary indicators. Two rounds of Delphi results showed that the expert authority, enthusiasm, and coordination coefficients were high. Constructs of the competency model that included seven primary indicators and 62 secondary indicators determined the weight of each index. The seven primary indicators included the following: clinical skills and medical services, disease prevention and health promotion, interpersonal communication skills, core values and professionalism, medical knowledge and lifelong learning ability, teamwork ability and scientific research ability. In conclusion, the use of the Delphi method to construct an initial model of Chinese physician competency is scientific and feasible. The initial competency model conforms to the characteristics and quality requirements of dentists in China and has a strong scientific basis. The dentist competency model should be used in the National Dental Licensing Examination in China.

  5. Deposition By Turbidity Currents In Intraslope Diapiric Minibasins: Results Of 1-D Experiments And Numerical Modeling

    Science.gov (United States)

    Lamb, M.; Toniolo, H.; Parker, G.

    2001-12-01

    The slope of the continental margin of the northern Gulf of Mexico is riddled with small basins resulting from salt tectonics. Each such minibasin is the result of local subsidence due to salt withdrawal, and is isolated from neighboring basins by ridges formed due to compensational uplift. The minibasins are gradually filled by turbidity currents, which are active at low sea stand. Experiments in a 1-D minibasin reveal that a turbidity current flowing into a deep minibasin must undergo a hydraulic jump and form a muddy pond. This pond may not spill out of the basin even with continuous inflow. The reason for this is the detrainment of water across the settling interface that forms at the top of the muddy pond. Results of both experiments and numerical modeling of the flow and the evolution of the deposit are presented. The numerical model is the first of its kind to capture both the hydraulic jump and the effect of detrainment in ponded turbidity currents.

  6. Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression

    Directory of Open Access Journals (Sweden)

    Lemieux Sébastien

    2006-08-01

    Full Text Available Abstract Background The identification of differentially expressed genes (DEGs from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level probe intensities, then deriving significance by comparing these expression levels between conditions. The proposed PL-LM (Probe-Level Linear Model method implements a linear model applied on the probe-level data to directly estimate the treatment effect. A finite mixture of Gaussian components is then used to identify DEGs using the coefficients estimated by the linear model. This approach can readily be applied to experimental design with or without replication. Results On a wholly defined dataset, the PL-LM method was able to identify 75% of the differentially expressed genes within 10% of false positives. This accuracy was achieved both using the three replicates per conditions available in the dataset and using only one replicate per condition. Conclusion The method achieves, on this dataset, a higher accuracy than the best set of tools identified by the authors of the dataset, and does so using only one replicate per condition.

  7. Comparison of five in vitro digestion models to in vivo experimental results: Lead bioaccessibility in the human gastrointestinal tract

    NARCIS (Netherlands)

    Wiele, T.R. van de; Oomen, A.G.; Wragg, J.; Cave, M.; Minekus, M.; Hack, A.; Cornelis, C.; Rompelberg, C.J.M.; Zwart, L.L. de; Klinck, B.; Wijnen, J. van; Verstraete, W.; Sips, A.J.A.M.

    2007-01-01

    This paper presents a multi-laboratory comparison study of in vitro models assessing bioaccessibility of soil-bound lead in the human gastrointestinal tract under simulated fasted and fed conditions. Oral bioavailability data from a previous human in vivo study on the same soil served as a reference

  8. Total hip arthroplasty after a previous pelvic osteotomy: A systematic review and meta-analysis.

    Science.gov (United States)

    Shigemura, T; Yamamoto, Y; Murata, Y; Sato, T; Tsuchiya, R; Wada, Y

    2018-06-01

    There are several reports regarding total hip arthroplasty (THA) after a previous pelvic osteotomy (PO). However, to our knowledge, until now there has been no formal systematic review and meta-analysis published to summarize the clinical results of THA after a previous PO. Therefore, we conducted a systematic review and meta-analysis of results of THA after a previous PO. We focus on these questions as follows: does a previous PO affect the results of subsequent THA, such as clinical outcomes, operative time, operative blood loss, and radiological parameters. Using PubMed, Web of Science, and Cochrane Library, we searched for relevant original papers. The pooling of data was performed using RevMan software (version 5.3, Cochrane Collaboration, Oxford, UK). A p-value50%, significant heterogeneity was assumed and a random-effects model was applied for the meta-analysis. A fixed-effects model was applied in the absence of significant heterogeneity. Eleven studies were included in this meta-analysis. The pooled results indicated that there was no significant difference in postoperative Merle D'Aubigne-Postel score (I 2 =0%, SMD=-0.15, 95% CI: -0.36 to 0.06, p=0.17), postoperative Harris hip score (I 2 =60%, SMD=-0.23, 95% CI: -0.50 to 0.05, p=0.10), operative time (I 2 =86%, SMD=0.37, 95% CI: -0.09 to 0.82, p=0.11), operative blood loss (I 2 =82%, SMD=0.23, 95% CI: -0.17 to 0.63, p=0.25), and cup abduction angle (I 2 =43%, SMD=-0.08, 95% CI: -0.25 to 0.09, p=0.38) between THA with and without a previous PO. However, cup anteversion angle of THA with a previous PO was significantly smaller than that of without a previous PO (I 2 =77%, SMD=-0.63, 95% CI: -1.13 to -0.13, p=0.01). Systematic review and meta-analysis of results of THA after a previous PO was performed. A previous PO did not affect the results of subsequent THA, except for cup anteversion. Because of the low quality evidence currently available, high-quality randomized controlled trials are required

  9. Practical models to estimate horizontal irradiance in clear sky conditions: Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Salazar, German A.; Hernandez, Alejandro L.; Saravia, Luis R. [Department of Physics, School of Exact Sciences, National University of Salta, Bolivia Avenue 5150, 4400 Salta Capital (Argentina); INENCO (Institute of Non Conventional Energy Research), Bolivia Avenue 5150, 4400 Salta Capital (Argentina)

    2010-11-15

    The Argentinean Northwest (ANW) is a high altitude region located alongside Los Andes Mountains. The ANW is also one of the most insolated regions in the world due to its altitude and particular climate. However, the characterization of the solar resource in the region is incomplete as there are no stations to measure solar radiation continuously and methodically. With irradiance data recently having been measured at three sites in the Salta Province, a study was carried out that resulted in a practical model to quickly and efficiently estimate the horizontal irradiance in high altitude sites in clear sky conditions. This model uses the altitude above sea level (A) as a variable and generates a representative clearness index as a result (k{sub t-R}) that is calculated for each site studied. This index k{sub t-R} is then used with the relative optical air mass and the extraterrestrial irradiance to estimate the instantaneous clearness index (k{sub t}). Subsequently, the index k{sub t-R} is corrected by introducing the atmospheric pressure in the definition of relative optical air mass proposed by Kasten. The results are satisfactory as errors in the irradiance estimations with respect to measured values do not exceed 5% for pressure corrected air masses AM{sub c} < 2. This model will be used in a feasibility study to locate sites for the installation of solar thermal power plants in the ANW. A prototype of a CLFR solar power plant is being built in the INENCO Campus, at the National University of Salta. (author)

  10. Community Consultation and Public Disclosure: Preliminary Results From A New Model

    Science.gov (United States)

    Ramsey, Cornelia A.; Quearry, Bonnie; Ripley, Elizabeth

    2011-01-01

    Emergency medicine research conducted under the exception from informed consent (EFIC) regulation enables critical scientific advancements. When EFIC is proposed, there is a requirement for broad community consultation and public disclosure regarding the risks and benefits of the study. At the present time, no clear guidelines or standards exist for conducting and evaluating the community consultation and public disclosure. This preliminary study tested the feasibility and acceptability of a new approach to community consultation and public disclosure for a large-scale EFIC trial by engaging community members in designing and conducting the strategies. The authors enrolled key community members (called Community Advocates for Research, or CARs) to use community-based participatory methods to design and implement community consultation and public disclosure. By partnering with community members who represent target populations for the research study, this new approach has demonstrated a feasible community consultation and public disclosure plan with greater community participation and less cost than previous studies. In a community survey, the percentage of community members reporting having heard about the EFIC trial more than doubled after employing the new approach. This article discusses initial implementation and results. PMID:21729187

  11. Vertical Instability in EAST: Comparison of Model Predictions with Experimental Results

    International Nuclear Information System (INIS)

    Qian Jinping; Wan Baonian; Shen Biao; Xiao Bingjia; Sun Youwen; Shi Yuejiang; Lin Shiyao; Li Jiangang; Gong Xianzu

    2008-01-01

    Growth rates of the axisymmetric mode in elongated plasmas in the experimental advanced superconducting tokamak (EAST) are measured with zero feedback gains and then compared with numerically calculated growth rates for the reconstructed shapes. The comparison is made after loss of vertical position control. The open-loop growth rates were scanned with the number of vessel eigenmodes, which up to 20 is enough to make the growth rates settled. The agreement between the growth rates measured experimentally and the growth rates determined numerically is good. The results show that a linear RZIP model is essentially good enough for the vertical position feedback control.

  12. Mathematic model of regional economy development by the final result of labor resources

    Science.gov (United States)

    Zaitseva, Irina; Malafeev, Oleg; Strekopytov, Sergei; Bondarenko, Galina; Lovyannikov, Denis

    2018-04-01

    This article presents the mathematic model of regional economy development based on the result of labor resources. The solution of a region development-planning problem is considered for the period of long-lasting planning taking into account the beginning and the end of the planned period. The challenge is to find the distribution of investments in the main and additional branches of the regional economy, which will provide simultaneous transaction of all major sectors of the regional economy from the given condition to the predetermined final state.

  13. Active vibration absorber for the CSI evolutionary model - Design and experimental results. [Controls Structures Interaction

    Science.gov (United States)

    Bruner, Anne M.; Belvin, W. Keith; Horta, Lucas G.; Juang, Jer-Nan

    1991-01-01

    The development of control of large flexible structures technology must include practical demonstrations to aid in the understanding and characterization of controlled structures in space. To support this effort, a testbed facility has been developed to study practical implementation of new control technologies under realistic conditions. The paper discusses the design of a second order, acceleration feedback controller which acts as an active vibration absorber. This controller provides guaranteed stability margins for collocated sensor/actuator pairs in the absence of sensor/actuator dynamics and computational time delay. Experimental results in the presence of these factors are presented and discussed. The robustness of this design under model uncertainty is demonstrated.

  14. Snpdat: Easy and rapid annotation of results from de novo snp discovery projects for model and non-model organisms

    Directory of Open Access Journals (Sweden)

    Doran Anthony G

    2013-02-01

    Full Text Available Abstract Background Single nucleotide polymorphisms (SNPs are the most abundant genetic variant found in vertebrates and invertebrates. SNP discovery has become a highly automated, robust and relatively inexpensive process allowing the identification of many thousands of mutations for model and non-model organisms. Annotating large numbers of SNPs can be a difficult and complex process. Many tools available are optimised for use with organisms densely sampled for SNPs, such as humans. There are currently few tools available that are species non-specific or support non-model organism data. Results Here we present SNPdat, a high throughput analysis tool that can provide a comprehensive annotation of both novel and known SNPs for any organism with a draft sequence and annotation. Using a dataset of 4,566 SNPs identified in cattle using high-throughput DNA sequencing we demonstrate the annotations performed and the statistics that can be generated by SNPdat. Conclusions SNPdat provides users with a simple tool for annotation of genomes that are either not supported by other tools or have a small number of annotated SNPs available. SNPdat can also be used to analyse datasets from organisms which are densely sampled for SNPs. As a command line tool it can easily be incorporated into existing SNP discovery pipelines and fills a niche for analyses involving non-model organisms that are not supported by many available SNP annotation tools. SNPdat will be of great interest to scientists involved in SNP discovery and analysis projects, particularly those with limited bioinformatics experience.

  15. Oil Spill Detection and Modelling: Preliminary Results for the Cercal Accident

    Science.gov (United States)

    da Costa, R. T.; Azevedo, A.; da Silva, J. C. B.; Oliveira, A.

    2013-03-01

    Oil spill research has significantly increased mainly as a result of the severe consequences experienced from industry accidents. Oil spill models are currently able to simulate the processes that determine the fate of oil slicks, playing an important role in disaster prevention, control and mitigation, generating valuable information for decision makers and the population in general. On the other hand, satellite Synthetic Aperture Radar (SAR) imagery has demonstrated significant potential in accidental oil spill detection, when they are accurately differentiated from look-alikes. The combination of both tools can lead to breakthroughs, particularly in the development of Early Warning Systems (EWS). This paper presents a hindcast simulation of the oil slick resulting from the Motor Tanker (MT) Cercal oil spill, listed by the Portuguese Navy as one of the major oil spills in the Portuguese Atlantic Coast. The accident took place nearby Leix˜oes Harbour, North of the Douro River, Porto (Portugal) on the 2nd of October 1994. The oil slick was segmented from available European Remote Sensing (ERS) satellite SAR images, using an algorithm based on a simplified version of the K-means clustering formulation. The image-acquired information, added to the initial conditions and forcings, provided the necessary inputs for the oil spill model. Simulations were made considering the tri-dimensional hydrodynamics in a crossscale domain, from the interior of the Douro River Estuary to the open-ocean on the Iberian Atlantic shelf. Atmospheric forcings (from ECMWF - the European Centre for Medium-Range Weather Forecasts and NOAA - the National Oceanic and Atmospheric Administration), river forcings (from SNIRH - the Portuguese National Information System of the Hydric Resources) and tidal forcings (from LNEC - the National Laboratory for Civil Engineering), including baroclinic gradients (NOAA), were considered. The lack of data for validation purposes only allowed the use of the

  16. Comparing offshore wind farm wake observed from satellite SAR and wake model results

    Science.gov (United States)

    Bay Hasager, Charlotte

    2014-05-01

    are modeled by various types of wake models. In the EERA DTOC project the model suite consists of engineering models (Ainslie, DWM, GLC, PARK, WASP/NOJ), simplified CFD models (FUGA, FarmFlow), full CFD models (CRES-flowNS, RANS), mesoscale model (SKIRON, WRF) and coupled meso-scale and microscale models. The comparison analysis between the satellite wind wake and model results will be presented and discussed. It is first time a comprehensive analysis is performed on this subject. The topic gains increasing importance because there is a growing need to precisely model also mid- and far-field wind farms wakes for development and planning of offshore wind farm clusters.

  17. Geochemistry of trace metals in a fresh water sediment: Field results and diagenetic modeling

    International Nuclear Information System (INIS)

    Canavan, R.W.; Cappellen, P. van; Zwolsman, J.J.G.; Berg, G.A. van den; Slomp, C.P.

    2007-01-01

    Concentrations of Fe, Mn, Cd, Co, Ni, Pb, and Zn were determined in pore water and sediment of a coastal fresh water lake (Haringvliet Lake, The Netherlands). Elevated sediment trace metal concentrations reflect anthropogenic inputs from the Rhine and Meuse Rivers. Pore water and sediment analyses, together with thermodynamic calculations, indicate a shift in trace metal speciation from oxide-bound to sulfide-bound over the upper 20 cm of the sediment. Concentrations of reducible Fe and Mn decline with increasing depth, but do not reach zero values at 20 cm depth. The reducible phases are relatively more important for the binding of Co, Ni, and Zn than for Pb and Cd. Pore waters exhibit supersaturation with respect to Zn, Pb, Co, and Cd monosulfides, while significant fractions of Ni and Co are bound to pyrite. A multi-component, diagenetic model developed for organic matter degradation was expanded to include Zn and Ni dynamics. Pore water transport of trace metals is primarily diffusive, with a lesser contribution of bioirrigation. Reactions affecting trace metal mobility near the sediment-water interface, especially sulfide oxidation and sorption to newly formed oxides, strongly influence the modeled estimates of the diffusive effluxes to the overlying water. Model results imply less efficient sediment retention of Ni than Zn. Sensitivity analyses show that increased bioturbation and sulfate availability, which are expected upon restoration of estuarine conditions in the lake, should increase the sulfide bound fractions of Zn and Ni in the sediments

  18. MELMRK 2.0: A description of computer models and results of code testing

    International Nuclear Information System (INIS)

    Wittman, R.S.; Denny, V.; Mertol, A.

    1992-01-01

    An advanced version of the MELMRK computer code has been developed that provides detailed models for conservation of mass, momentum, and thermal energy within relocating streams of molten metallics during meltdown of Savannah River Site (SRS) reactor assemblies. In addition to a mechanistic treatment of transport phenomena within a relocating stream, MELMRK 2.0 retains the MOD1 capability for real-time coupling of the in-depth thermal response of participating assembly heat structure and, further, augments this capability with models for self-heating of relocating melt owing to steam oxidation of metallics and fission product decay power. As was the case for MELMRK 1.0, the MOD2 version offers state-of-the-art numerics for solving coupled sets of nonlinear differential equations. Principal features include application of multi-dimensional Newton-Raphson techniques to accelerate convergence behavior and direct matrix inversion to advance primitive variables from one iterate to the next. Additionally, MELMRK 2.0 provides logical event flags for managing the broad range of code options available for treating such features as (1) coexisting flow regimes, (2) dynamic transitions between flow regimes, and (3) linkages between heatup and relocation code modules. The purpose of this report is to provide a detailed description of the MELMRK 2.0 computer models for melt relocation. Also included are illustrative results for code testing, as well as an integrated calculation for meltdown of a Mark 31a assembly

  19. Modeling of Particle Acceleration at Multiple Shocks Via Diffusive Shock Acceleration: Preliminary Results

    Science.gov (United States)

    Parker, L. N.; Zank, G. P.

    2013-12-01

    Successful forecasting of energetic particle events in space weather models require algorithms for correctly predicting the spectrum of ions accelerated from a background population of charged particles. We present preliminary results from a model that diffusively accelerates particles at multiple shocks. Our basic approach is related to box models (Protheroe and Stanev, 1998; Moraal and Axford, 1983; Ball and Kirk, 1992; Drury et al., 1999) in which a distribution of particles is diffusively accelerated inside the box while simultaneously experiencing decompression through adiabatic expansion and losses from the convection and diffusion of particles outside the box (Melrose and Pope, 1993; Zank et al., 2000). We adiabatically decompress the accelerated particle distribution between each shock by either the method explored in Melrose and Pope (1993) and Pope and Melrose (1994) or by the approach set forth in Zank et al. (2000) where we solve the transport equation by a method analogous to operator splitting. The second method incorporates the additional loss terms of convection and diffusion and allows for the use of a variable time between shocks. We use a maximum injection energy (Emax) appropriate for quasi-parallel and quasi-perpendicular shocks (Zank et al., 2000, 2006; Dosch and Shalchi, 2010) and provide a preliminary application of the diffusive acceleration of particles by multiple shocks with frequencies appropriate for solar maximum (i.e., a non-Markovian process).

  20. Insight into collision zone dynamics from topography: numerical modelling results and observations

    Directory of Open Access Journals (Sweden)

    A. D. Bottrill

    2012-11-01

    Full Text Available Dynamic models of subduction and continental collision are used to predict dynamic topography changes on the overriding plate. The modelling results show a distinct evolution of topography on the overriding plate, during subduction, continental collision and slab break-off. A prominent topographic feature is a temporary (few Myrs basin on the overriding plate after initial collision. This "collisional mantle dynamic basin" (CMDB is caused by slab steepening drawing, material away from the base of the overriding plate. Also, during this initial collision phase, surface uplift is predicted on the overriding plate between the suture zone and the CMDB, due to the subduction of buoyant continental material and its isostatic compensation. After slab detachment, redistribution of stresses and underplating of the overriding plate cause the uplift to spread further into the overriding plate. This topographic evolution fits the stratigraphy found on the overriding plate of the Arabia-Eurasia collision zone in Iran and south east Turkey. The sedimentary record from the overriding plate contains Upper Oligocene-Lower Miocene marine carbonates deposited between terrestrial clastic sedimentary rocks, in units such as the Qom Formation and its lateral equivalents. This stratigraphy shows that during the Late Oligocene–Early Miocene the surface of the overriding plate sank below sea level before rising back above sea level, without major compressional deformation recorded in the same area. Our modelled topography changes fit well with this observed uplift and subsidence.

  1. The comparative analysis of model and prototype test results of Bulb turbine

    International Nuclear Information System (INIS)

    Benisek, M; Bozic, I; Ignjatovic, B

    2010-01-01

    This paper presents the problem of the hydropower plant oblique water inflow and its influence on the turbines operation. Oblique water inflow on the low head hydropower plant with bulb turbines influences turbine characteristics. The characteristics change occurs due to swirl incidence in the turbine inlet which spreads to the guide vanes inlet. Downstream, the flow conditions change is caused in the turbine runner in relation to the flow conditions without swirl inflow. Special attention is paid to the phenomenon of swirl flow incidence in the turbine conduit. With the aim of presenting and analyzing the oblique water inflow consequences on the hydropower plant operation, the existing turbine model tests results, performed in the laboratories, and the in situ prototype testing results have been used.

  2. Creatinine generation from kinetic modeling with or without postdialysis serum creatinine measurement: results from the HEMO study.

    Science.gov (United States)

    Daugirdas, John T; Depner, Thomas A

    2017-11-01

    A convenient method to estimate the creatinine generation rate and measures of creatinine clearance in hemodialysis patients using formal kinetic modeling and standard pre- and postdialysis blood samples has not been described. We used data from 366 dialysis sessions characterized during follow-up month 4 of the HEMO study, during which cross-dialyzer clearances for both urea and creatinine were available. Blood samples taken at 1 h into dialysis and 30 min and 60 min after dialysis were used to determine how well a two-pool kinetic model could predict creatinine concentrations and other kinetic parameters, including the creatinine generation rate. An extrarenal creatinine clearance of 0.038 l/kg/24 h was included in the model. Diffusive cross-dialyzer clearances of urea [230 (SD 37 mL/min] correlated well (R2 = 0.78) with creatinine clearances [164 (SD 30) mL/min]. When the effective diffusion volume flow rate was set at 0.791 times the blood flow rate for the cross-dialyzer clearance measurements at 1 h into dialysis, the mean calculated volume of creatinine distribution averaged 29.6 (SD 7.2) L], compared with 31.6 (SD 7.0) L for urea (P creatinine generation rate [1183 (SD 463) mg/day] averaged 100.1 % (SD 29; median 99.3) of that predicted in nondialysis patients by an anthropometric equation. A simplified method for modeling the creatinine generation rate using the urea distribution volume and urea dialyzer clearance without use of the postdialysis serum creatinine measurement gave results for creatinine generation rate [1187 (SD 475) mg/day; that closely matched the value calculated using the formally modeled value, R2 = 0.971]. Our analysis confirms previous findings of similar distribution volumes for creatinine and urea. After taking extra-renal clearance into consideration, the creatinine generation rate in dialysis patients is similar to that in nondialysis patients. A simplified method based on urea clearance

  3. Squat Biomechanical Modeling Results from Exercising on the Hybrid Ultimate Lifting Kit

    Science.gov (United States)

    Gallo, Christopher A.; Thompson, William K.; Lewandowski, Beth E.; Jagodnik, Kathleen M.

    2016-01-01

    Long duration space travel will expose astronauts to extended periods of reduced gravity. Since gravity is not present to aid loading, astronauts will use resistive and aerobic exercise regimes for the duration of the space flight to minimize loss of bone density, muscle mass and aerobic capacity that occurs during exposure to a reduced gravity environment. Unlike the International Space Station (ISS), the area available for an exercise device in the next generation of spacecraft is limited and therefore compact resistance exercise device prototypes are being developed. The Advanced Resistive Exercise Device (ARED) currently on the ISS is being used as a benchmark for the functional performance of these new devices. Biomechanical data collection and computational modeling aid the device design process by quantifying the joint torques and the musculoskeletal forces that occur during exercises performed on the prototype devices. The computational models currently under development utilize the OpenSim software, an open source code for musculoskeletal modeling, with biomechanical input data from test subjects for estimation of muscle and joint loads. The subjects are instrumented with reflective markers for motion capture data collection while exercising on the Hybrid Ultimate Lifting Kit (HULK) prototype device. Ground reaction force data is collected with force plates under the feet and device loading is recorded through load cells internal to the HULK. Test variables include applied device load, narrow or wide foot stance, slow or fast cadence and the harness or long bar interface between the test subject and the device. Data is also obtained using free weights for a comparison to the resistively loaded exercise device. This data is input into the OpenSim biomechanical model, which has been scaled to match the anthropometrics of the test subject, to calculate the body loads. The focus of this presentation is to summarize the results from the full squat exercises

  4. Cladding oxidation during air ingress. Part II: Synthesis of modelling results

    International Nuclear Information System (INIS)

    Beuzet, E.; Haurais, F.; Bals, C.; Coindreau, O.; Fernandez-Moguel, L.; Vasiliev, A.; Park, S.

    2016-01-01

    Highlights: • A state-of-the-art for air oxidation modelling in the frame of severe accident is done. • Air oxidation models from main severe accident codes are detailed. • Simulations from main severe accident codes are compared against experimental results. • Perspectives in terms of need for further model development and experiments are given. - Abstract: Air ingress is a potential risk in some low probable situations of severe accidents in a nuclear power plant. Air is a highly oxidizing atmosphere that can lead to an enhanced Zr-based cladding oxidation and core degradation affecting the release of fission products. This is particularly true speaking about ruthenium release, due to its high radiotoxicity and its ability to form highly volatile oxides in a significant manner in presence of air. The oxygen affinity is decreasing from the Zircaloy cladding, fuel and ruthenium inclusions. It is consequently of great need to understand the phenomena governing cladding oxidation by air as a prerequisite for the source term issues in such scenarios. In the past years, many works have been done on cladding oxidation by air under severe accident conditions. This paper with in addition the paper “Cladding oxidation during air ingress – Part I: Synthesis of experimental results” of this journal issue aim at assessing the state of the art on this phenomenon. In this paper, the modelling of air ingress phenomena in the main severe accident codes (ASTEC, ATHLET-CD, MAAP, MELCOR, RELAP/SCDAPSIM, SOCRAT) is described in details, as well as the validation against the integral experiments QUENCH-10, QUENCH-16 and PARAMETER-SF4. A full review of cladding oxidation by air is thus established.

  5. SPND detectors response at the control rod drop in WWER-1000. Measurement and modelling results

    International Nuclear Information System (INIS)

    Mitin, V.; Milto, N.; Shishkov, L.; Tsyganov, S.; Kuzmichev, M.

    2006-01-01

    The paper analyzes and discusses possibility of neutron flux inspection in the WWER core during fast dynamic processes applying existing in-core monitoring system. The structure and functions of the system, basic principal of detector functioning and its temporal parameters are described briefly. To assess the ability of such dynamic monitoring the event with control rod drop happened during operation of Kozloduy NPP Unit 5 is observed - at the level of power close to nominal one of the rod from control group shifted to the lowest position at-2 seconds. In-core detectors readings at the process were registered and processed with mathematical methods that allow to single out only the prompt part of the signal. Results of the processing are presented. Furthermore, the process observing have been modeled with 3D dynamic code NOSTRA. Results of modeling are presenting in a paper, and comparing with experimental ones. A good agreement achieved. The analysis of measurements and its imitation give a hope that with an aggregate signal of detectors the measurement of control rod worth could be provided, and it allows to avoid of influence of spatial effects that are significant at standard technique with ex-core ion chambers (Authors)

  6. Hawaii Solar Integration Study: Solar Modeling Developments and Study Results; Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Orwig, K.; Corbus, D.; Piwko, R.; Schuerger, M.; Matsuura, M.; Roose, L.

    2012-12-01

    The Hawaii Solar Integration Study (HSIS) is a follow-up to the Oahu Wind Integration and Transmission Study completed in 2010. HSIS focuses on the impacts of higher penetrations of solar energy on the electrical grid and on other generation. HSIS goes beyond the island of Oahu and investigates Maui as well. The study examines reserve strategies, impacts on thermal unit commitment and dispatch, utilization of energy storage, renewable energy curtailment, and other aspects of grid reliability and operation. For the study, high-frequency (2-second) solar power profiles were generated using a new combined Numerical Weather Prediction model/ stochastic-kinematic cloud model approach, which represents the 'sharp-edge' effects of clouds passing over solar facilities. As part of the validation process, the solar data was evaluated using a variety of analysis techniques including wavelets, power spectral densities, ramp distributions, extreme values, and cross correlations. This paper provides an overview of the study objectives, results of the solar profile validation, and study results.

  7. Application of the results of carbon pellet modeling to the problem of plasma penetration

    International Nuclear Information System (INIS)

    Vahala, L.L.; El Cashlan, A.G.; Gerdin, G.A.; Parks, P.B.

    1990-01-01

    The assumptions of the evaporation model for low-Z pellets interacting with magnetic fusion plasmas developed by P. B. Parks are tested. These assumptions are that the vapor density profile in the region adjacent to the pellet surface, falls off with radial distance as r -α , where 5 zi , is much less than a flow time for the vapor in this same region τ f (i.e. for r zi much-lt τ f , is tested at the sonic radius using the results from atomic physics and the low-Z evaporation model. It is found that indeed τ zi much-lt τ f for plasmas with parameters close to thermonuclear conditions (e.g. TFTR and CIT), but not for those of smaller Tokamaks such as TEXT. The results of pellet penetration calculations for the conditions of the TEXT carbon-pellet injection experiments are presented which show better agreement with experiment if the shielding fraction is calculated at each step of the pellet-penetration calculation, the effect of ionization is ignored, and if the effect of possible uncertainties in the background plasma parameters is included. 14 refs., 3 figs., 3 tabs

  8. Exposure to Engineered Nanomaterial Results in Disruption of Brush Borders in Epithelia Models in vitro

    Science.gov (United States)

    Faust, James J.

    Engineered nanoparticles (NP; 10-9 m) have found use in a variety of consumer goods and medical devices because of the unique changes in material properties that occur when synthesized on the nanoscale. Although many definitions for nanoparticle exist, from the perspective of size, nanoparticle is defined as particles with diameters less than 100 nm in any external dimension. Examples of their use include titanium dioxide added as a pigment in products intended to be ingested by humans, silicon dioxide NPs are used in foods as an anticaking agent, and gold or iron oxide NPs can be used as vectors for drug delivery or contrast agents for specialized medical imaging. Although the intended use of these NPs is often to improve human health, it has come to the attention of investigators that NPs can have unintended or even detrimental effects on the organism. This work describes one such unintended effect of NP exposure from the perspective of exposure via the oral route. First, this Dissertation will explain an event referred to as brush border disruption that occurred after nanoparticles interacted with an in vitro model of the human intestinal epithelium. Second, this Dissertation will identify and characterize several consumer goods that were shown to contain titanium dioxide that are intended to be ingested. Third, this Dissertation shows that sedimentation due to gravity does not artifactually result in disruption of brush borders as a consequence of exposure to food grade titanium dioxide in vitro. Finally, this Dissertation will demonstrate that iron oxide nanoparticles elicited similar effects after exposure to an in vitro brush border expressing model of the human placenta. Together, these data suggest that brush border disruption is not an artifact of the material/cell culture model, but instead represents a bona fide biological response as a result of exposure to nanomaterial.

  9. Response to health insurance by previously uninsured rural children.

    Science.gov (United States)

    Tilford, J M; Robbins, J M; Shema, S J; Farmer, F L

    1999-08-01

    To examine the healthcare utilization and costs of previously uninsured rural children. Four years of claims data from a school-based health insurance program located in the Mississippi Delta. All children who were not Medicaid-eligible or were uninsured, were eligible for limited benefits under the program. The 1987 National Medical Expenditure Survey (NMES) was used to compare utilization of services. The study represents a natural experiment in the provision of insurance benefits to a previously uninsured population. Premiums for the claims cost were set with little or no information on expected use of services. Claims from the insurer were used to form a panel data set. Mixed model logistic and linear regressions were estimated to determine the response to insurance for several categories of health services. The use of services increased over time and approached the level of utilization in the NMES. Conditional medical expenditures also increased over time. Actuarial estimates of claims cost greatly exceeded actual claims cost. The provision of a limited medical, dental, and optical benefit package cost approximately $20-$24 per member per month in claims paid. An important uncertainty in providing health insurance to previously uninsured populations is whether a pent-up demand exists for health services. Evidence of a pent-up demand for medical services was not supported in this study of rural school-age children. States considering partnerships with private insurers to implement the State Children's Health Insurance Program could lower premium costs by assembling basic data on previously uninsured children.

  10. Compound analysis of gallstones using dual energy computed tomography-Results in a phantom model

    Energy Technology Data Exchange (ETDEWEB)

    Bauer, Ralf W., E-mail: ralfwbauer@aol.co [Department of Diagnostic and Interventional Radiology, Clinic of the Goethe University Frankfurt, Theodor-Stern-Kai 7, 60596 Frankfurt (Germany); Schulz, Julian R., E-mail: julian.schulz@t-online.d [Department of Diagnostic and Interventional Radiology, Clinic of the Goethe University Frankfurt, Theodor-Stern-Kai 7, 60596 Frankfurt (Germany); Zedler, Barbara, E-mail: zedler@em.uni-frankfurt.d [Department of Forensic Medicine, Clinic of the Goethe University Frankfurt, Kennedyallee 104, 60596 Frankfurt (Germany); Graf, Thomas G., E-mail: thomas.gt.graf@siemens.co [Siemens AG Healthcare Sector, Computed Tomography, Physics and Applications, Siemensstrasse 1, 91313 Forchheim (Germany); Vogl, Thomas J., E-mail: t.vogl@em.uni-frankfurt.d [Department of Diagnostic and Interventional Radiology, Clinic of the Goethe University Frankfurt, Theodor-Stern-Kai 7, 60596 Frankfurt (Germany)

    2010-07-15

    Purpose: The potential of dual energy computed tomography (DECT) for the analysis of gallstone compounds was investigated. The main goal was to find parameters, that can reliably define high percentage (>70%) cholesterol stones without calcium components. Materials and methods: 35 gallstones were analyzed with DECT using a phantom model. Stone samples were put into specimen containers filled with formalin. Containers were put into a water-filled cylindrical acrylic glass phantom. DECT scans were performed using a tube voltage/current of 140 kV/83 mAs (tube A) and 80 kV/340 mAs (tube B). ROI-measurements to determine CT attenuation of each sector of the stones that had different appearance on the CT images were performed. Finally, semi-quantitative infrared spectroscopy (FTIR) of these sectors was performed for chemical analysis. Results: ROI-measurements were performed in 45 different sectors in 35 gallstones. Sectors containing >70% of cholesterol and no calcium component (n = 20) on FTIR could be identified with 95% sensitivity and 100% specificity on DECT. These sectors showed typical attenuation of -8 {+-} 4 HU at 80 kV and +22 {+-} 3 HU at 140 kV. Even the presence of a small calcium component (<10%) hindered the reliable identification of cholesterol components as such. Conclusion: Dual energy CT allows for reliable identification of gallstones containing a high percentage of cholesterol and no calcium component in this pre-clinical phantom model. Results from in vivo or anthropomorphic phantom trials will have to confirm these results. This may enable the identification of patients eligible for non-surgical treatment options in the future.

  11. Compound analysis of gallstones using dual energy computed tomography-Results in a phantom model

    International Nuclear Information System (INIS)

    Bauer, Ralf W.; Schulz, Julian R.; Zedler, Barbara; Graf, Thomas G.; Vogl, Thomas J.

    2010-01-01

    Purpose: The potential of dual energy computed tomography (DECT) for the analysis of gallstone compounds was investigated. The main goal was to find parameters, that can reliably define high percentage (>70%) cholesterol stones without calcium components. Materials and methods: 35 gallstones were analyzed with DECT using a phantom model. Stone samples were put into specimen containers filled with formalin. Containers were put into a water-filled cylindrical acrylic glass phantom. DECT scans were performed using a tube voltage/current of 140 kV/83 mAs (tube A) and 80 kV/340 mAs (tube B). ROI-measurements to determine CT attenuation of each sector of the stones that had different appearance on the CT images were performed. Finally, semi-quantitative infrared spectroscopy (FTIR) of these sectors was performed for chemical analysis. Results: ROI-measurements were performed in 45 different sectors in 35 gallstones. Sectors containing >70% of cholesterol and no calcium component (n = 20) on FTIR could be identified with 95% sensitivity and 100% specificity on DECT. These sectors showed typical attenuation of -8 ± 4 HU at 80 kV and +22 ± 3 HU at 140 kV. Even the presence of a small calcium component (<10%) hindered the reliable identification of cholesterol components as such. Conclusion: Dual energy CT allows for reliable identification of gallstones containing a high percentage of cholesterol and no calcium component in this pre-clinical phantom model. Results from in vivo or anthropomorphic phantom trials will have to confirm these results. This may enable the identification of patients eligible for non-surgical treatment options in the future.

  12. Effects of stream topology on ecological community results from neutral models

    Science.gov (United States)

    While neutral theory and models have stimulated considerable literature, less well investigated is the effect of topology on neutral metacommunity model simulations. We implemented a neutral metacommunity model using two different stream network topologies, a widely branched netw...

  13. 75 FR 28485 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Science.gov (United States)

    2010-05-21

    ... Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft... Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.): Amendment 39... previously held by Israel Aircraft Industries, Ltd.) Model Gulfstream 100 airplanes; and Model Astra SPX and...

  14. The BirthPlace collaborative practice model: results from the San Diego Birth Center Study.

    Science.gov (United States)

    Swartz; Jackson; Lang; Ecker; Ganiats; Dickinson; Nguyen

    1998-07-01

    compared along with cost-effectiveness and acceptance of the model by patients. Data collection occurred primarily through medical record abstraction with the addition of two patient questionnaires. Comparability of the cohorts was established by using a validated methodology to determine medical/perinatal risk and birth center eligibility, which included assessment by two CNMs and an independent blind review by a perinatologist. The cost analysis uses a resource-utilization approach and new methodologies such as activity-based-costing to compare costs from both the perspective of the payor and the health care provider. Patient satisfaction was measured using a self-administered patient questionnaire.Results: Current preliminary results from approximately 38% of the final expected study sample are available. Crude and adjusted analysis have been conducted. Overall, the preliminary results suggest similar morbidity and mortality in the two groups. Fetal deaths are 0.75% in the index and 0.64% in the comparison group, with early neonatal deaths at 0.26% and 0.23%, respectively. The traditional care group showed adjusted rate differences of 5.83% more major maternal intrapartum complications and 9% more NICU admissions. While the birth center group showed adjusted rate differences of 5.5% more low birth weight and 0.95% more preterm birth. For other outcomes, the birth center group showed an adjusted rate difference of 22.34% more exclusive breastfeeding at discharge. Also, there was less utilization of cesarean section and assisted delivery in the birth center group as compared to the traditional care group. The adjusted rate difference for normal spontaneous vaginal deliveries in nulliparas was 10.23% more in the birth center group, with similar results in multiparas with and without history of cesarean (28.88% and 7.84%, respectively). Preliminary results also show that the average total cost for pregnancy-related services paid by California Medicaid was $4,550 for the

  15. Uranium dioxide-sodium interactions. Development of a theoretical model. Fitting of this model to the experimental results

    International Nuclear Information System (INIS)

    Syrmalenios, Panayotis

    1973-01-01

    This research thesis addresses the issue of safety of fast neutron reactors, and more particularly is a contribution of the study of mechanisms of interaction between molten fuel and sodium. It aims at developing tools of prediction of c