WorldWideScience

Sample records for previous geologic studies

  1. Geologic studies

    International Nuclear Information System (INIS)

    Wayland, T.E.; Rood, A.

    1983-01-01

    The modern Great Divide Basin is the end product of natural forces influenced by the Green River lake system, Laramide tectonism, and intermittent volcanic events. It ranks as one of the most complex structural and stratigtaphic features within the Tertiary basins of Wyoming. Portions of the Great Divide Basin and adjoining areas in Wyoming have been investigated by applying detailed and region exploration methods to known uranium deposits located within the Red Desert portions of the basin. Geologic field investigations conducted by Bendix Field Engineering Corporaton (Bendix) were restricted to reconnaissance observations made during infrequent visits to the project area by various Bendix personnel. Locations of the most comprehensive field activities are shown in Figure II-1. The principal source fo data for geologic studies of the Red Desert project area has been information and materials furnished by industry. Several hundred holes have been drilled by various groups to delineate the uranium deposits. Results from Bendix-drilled holes at selected locations within the project area are summarized in Table II-1. Additional details and gross subsurface characteristics are illustrated in cross sections; pertinent geologic features are illustrated in plan maps. Related details of continental sedimentation that pertain to the Wyoming Basins generally, and the project area specificially, are discussed in subsections of this Geologic Studies section

  2. Thermoluminescence studies in geology

    International Nuclear Information System (INIS)

    Sankaran, A.V.; Sunta, C.M.; Nambi, K.S.V.; Bapat, V.N.

    1980-01-01

    Even though the phenomenon of thermoluminescence is well studied, particularly over last 3 decades, its potentialities in the field of geology have not been adequately evaluated. In this report several useful applications of TL in mineralogy, petrogenesis, stratigraphy, tectonics, ore-prospecting and other branches have been identified with particular emphasis to the Indian scene. Important areas in the country that may provide the basic material for such studies are indicated at the end along with brief geological or mineralogical accounts. (auth.)

  3. Review of previous geophysical and geological studies

    Digital Repository Service at National Institute of Oceanography (India)

    Levchenko, O.V.; Neprochnov, Y.P.; Rao, D.G.; Subrahmanyam, C.; Murthy, K.S.R.

    stream_size 5 stream_content_type text/plain stream_name Mem_Geol_Soc_India_39_5.pdf.txt stream_source_info Mem_Geol_Soc_India_39_5.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 ...

  4. Geologic environmental study

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chun Soo; Bae, Dae Seok; Kim, Kyung Su; Park, Byung Yoon; Koh, Young Kown; Chun, Kwan Sik; Kim, Jhin Wung

    2000-05-01

    The geoscience research works are focused on the production of geologic basic data accompanying with the technical development of geology and hydrogeologic characterization. The lithology of the Korean peninsula consists of a complex structure of 29 rock types from Archean to Quaternary. The wide distribution of Mesozoic plutonic rock is an important consideration as a potential host rock allowing flexibility of siting. The recent tectonic activities are limited to localized particular area, which can be avoided by excluding in the early stage of siting. Three rock types such as plutonic rocks, crystalline gneisses and massive volcanic rocks were suggested as the preferred host rocks for the further study on HLW disposal system. This report contains grouping of regional faults, and on the distributional characteristics of faults and fractures(zones) in terms of lithological domain and tectonical provinces. The regional groundwater regime can be grouped into 3 regimes by tectonic setting and four groundwater regions based on an altitute. Groundwaters can be grouped by their chemistry and host rocks. The origin of groundwater was proposed by isotope ({sup 1}8O, {sup 2}H, {sup 1}3C, {sup 3}4S, {sup 8}7Sr, {sup 1}5N) studies and the residence time of groundwater was inferred from their tritium contents. Based on the geochemical and isotope characteristics, the geochemical evolutions of each types of groundwater were simulated using SOLVEQ/CHILLER and PHREEQC programs.

  5. Discovery of previously unrecognised local faults in London, UK, using detailed 3D geological modelling

    Science.gov (United States)

    Aldiss, Don; Haslam, Richard

    2013-04-01

    In parts of London, faulting introduces lateral heterogeneity to the local ground conditions, especially where construction works intercept the Palaeogene Lambeth Group. This brings difficulties to the compilation of a ground model that is fully consistent with the ground investigation data, and so to the design and construction of engineering works. However, because bedrock in the London area is rather uniform at outcrop, and is widely covered by Quaternary deposits, few faults are shown on the geological maps of the area. This paper discusses a successful resolution of this problem at a site in east central London, where tunnels for a new underground railway station are planned. A 3D geological model was used to provide an understanding of the local geological structure, in faulted Lambeth Group strata, that had not been possible by other commonly-used methods. This model includes seven previously unrecognised faults, with downthrows ranging from about 1 m to about 12 m. The model was constructed in the GSI3D geological modelling software using about 145 borehole records, including many legacy records, in an area of 850 m by 500 m. The basis of a GSI3D 3D geological model is a network of 2D cross-sections drawn by a geologist, generally connecting borehole positions (where the borehole records define the level of the geological units that are present), and outcrop and subcrop lines for those units (where shown by a geological map). When the lines tracing the base of each geological unit within the intersecting cross-sections are complete and mutually consistent, the software is used to generate TIN surfaces between those lines, so creating a 3D geological model. Even where a geological model is constructed as if no faults were present, changes in apparent dip between two data points within a single cross-section can indicate that a fault is present in that segment of the cross-section. If displacements of similar size with the same polarity are found in a series

  6. A Study of the Education of Geology

    Science.gov (United States)

    Berglin, R. S.; Baldridge, A. M.; Buxner, S.; Crown, D. A.

    2013-12-01

    An Evaluation and Assessment Method for Workshops in Science Education and Resources While many professional development workshops train teachers with classroom activities for students, Workshops in Science Education and Resources (WISER): Planetary Perspectives is designed to give elementary and middle school teachers the deeper knowledge necessary to be confident teaching the earth and space science content in their classrooms. Two WISER workshops, Deserts of the Solar System and Volcanoes of the Solar System, place an emphasis on participants being able to use learned knowledge to describe or 'tell the story of' a given rock. In order to understand how participants' knowledge and ability to tell the story changes with instruction, we are investigating new ways of probing the understanding of geologic processes. The study will include results from both college level geology students and teachers, focusing on their understanding of geologic processes and the rock cycle. By studying how new students process geologic information, teachers may benefit by learning how to better teach similar information. This project will help to transfer geologic knowledge to new settings and assess education theories for how people learn. Participants in this study include teachers participating in the WISER program in AZ and introductory level college students at St. Mary's College of California. Participants will be videotaped drawing out their thought process on butcher paper as they describe a given rock. When they are done, they will be asked to describe what they have put on the paper and this interview will be recorded. These techniques will be initially performed with students at St. Mary's College of California to understand how to best gather information. An evaluation of their prior knowledge and previous experience will be determined, and a code of their thought process will be recorded. The same students will complete a semester of an introductory college level Physical

  7. Age determination and geological studies

    International Nuclear Information System (INIS)

    Stevens, R.D.; Delabio, R.N.; Lachance, G.R.

    1982-01-01

    Two hundred and eight potassium-argon age determinations carried out on Canadian rocks and minerals are reported. Each age determination is accompanied by a description of the rock and mineral concentrate used; brief interpretative comments regarding the geological significance of each age are also provided where possible. The experimental procedures employed are described in brief outline and the constants used in the calculation of ages are listed. Two geological time-scales are reproduced in tabular form for ready reference and an index of all Geological Survey of Canada K-Ar age determinations published in this format has been prepared using NTS quadrangles as the primary reference

  8. The laboratories of geological studies

    International Nuclear Information System (INIS)

    1994-01-01

    This educational document comprises 4 booklets in a folder devoted to the presentation of the ANDRA's activities in geological research laboratories. The first booklet gives a presentation of the missions of the ANDRA (the French agency for the management of radioactive wastes) in the management of long life radioactive wastes. The second booklet describes the approach of waste disposal facilities implantation. The third booklet gives a brief presentation of the scientific program concerning the underground geologic laboratories. The last booklet is a compilation of questions and answers about long-life radioactive wastes, the research and works carried out in geologic laboratories, the public information and the local socio-economic impact, and the storage of radioactive wastes in deep geological formations. (J.S.)

  9. Geology

    Data.gov (United States)

    Kansas Data Access and Support Center — This database is an Arc/Info implementation of the 1:500,000 scale Geology Map of Kansas, M­23, 1991. This work wasperformed by the Automated Cartography section of...

  10. A quantitative geologic study of heterogeneity

    International Nuclear Information System (INIS)

    Davis, J.M.; Phillips, F.M.

    1990-01-01

    Spatial variation of hydraulic conductivity has been generally recognized as the dominant medium-dependent control on the transport and dispersion of contaminants in ground water. An empirical study focusing on the relationship between patters of sedimentology and patterns of permeability is being conducted at an outcrop of the Pliocene/Pleistocene Sierra Ladrones formation, central New Mexico. Methods of geostatistics and sedimentary basin analysis are employed to study the problem of aquifer heterogeneity. An air permeameter provides a means of obtaining extensive field measurements of air-flow rates through the sediments. These flow rates are subsequently used to characterize the permeability distribution of the outcrop. Both the geologic information and the air-flow rate data provide the basis for analysis of aquifer heterogeneity. Preliminary geologic mapping indicates that the sediments in the study area are the products of an arid fluvial/interfluvial depositional environment. Probability distribution analysis of the air-flow rate data suggests that the permeability of these sediments is log-normally distributed. The air permeability data are used to estimate variograms and correlation lengths in both the horizontal and vertical directions. At the scale of 10's of centimeters, the horizontal variograms exhibit exponential variogram behaviour . When two distinct lithologies are present, the correlation structure appears to be a nested exponential. Variogram analysis of estimated mean permeability at the scale of meters also shows evidence of a nested correlation structure in the horizontal direction and a periodic correlation structure in the vertical direction. Results of this study suggest that there is a direct connection between observable geologic structure and permeability statistics. (Author) (35 refs., 10 figs., 5 tabs.)

  11. Studies of natural analogues and geological systems

    International Nuclear Information System (INIS)

    Brandberg, F.; Grundfelt, B.; Hoeglund, L.; Skagius K.; Karlsson, F.; Smellie, J.

    1993-04-01

    This review has involved studies of natural analogues and natural geological systems leading to the identification and quantification of processes and features of importance to the performance and safety of repositories for radioactive waste. The features and processes selected for the study comprise general geochemical issues related to the performance of the near- and far-field, the performance and durability of construction materials and the effects of glaciation. For each of these areas a number of potentially important processes for repository performance have been described, and evidence for their existence, as well as quantification of parameters of models describing the processes have been sought from major natural analogue studies and site investigations. The review has aimed at covering a relatively broad range of issues at the expense of in-depth analysis. The quantitative data presented are in most cases compilations of data from the literature; in a few cases results of evaluations made within the current project are included

  12. Geological studies in Alaska by the U.S. Geological Survey, 1999

    Science.gov (United States)

    Gough, Larry P.; Wilson, Frederic H.

    2001-01-01

    The collection of nine papers that follow continue the series of U.S. Geological Survey (USGS) investigative reports in Alaska under the broad umbrella of the geologic sciences. The series presents new and sometimes preliminary findings that are of interest to earth scientists in academia, government, and industry; to land and resource managers; and to the general public. Reports presented in Geologic Studies in Alaska cover a broad spectrum of topics from various parts of the State (fig. 1), serving to emphasize the diversity of USGS efforts to meet the Nation's needs for earth-science information in Alaska.

  13. Radon anomalies prior to earthquakes (1). Review of previous studies

    International Nuclear Information System (INIS)

    Ishikawa, Tetsuo; Tokonami, Shinji; Yasuoka, Yumi; Shinogi, Masaki; Nagahama, Hiroyuki; Omori, Yasutaka; Kawada, Yusuke

    2008-01-01

    The relationship between radon anomalies and earthquakes has been studied for more than 30 years. However, most of the studies dealt with radon in soil gas or in groundwater. Before the 1995 Hyogoken-Nanbu earthquake, an anomalous increase of atmospheric radon was observed at Kobe Pharmaceutical University. The increase was well fitted with a mathematical model related to earthquake fault dynamics. This paper reports the significance of this observation, reviewing previous studies on radon anomaly before earthquakes. Groundwater/soil radon measurements for earthquake prediction began in 1970's in Japan as well as foreign countries. One of the most famous studies in Japan is groundwater radon anomaly before the 1978 Izu-Oshima-kinkai earthquake. We have recognized the significance of radon in earthquake prediction research, but recently its limitation was also pointed out. Some researchers are looking for a better indicator for precursors; simultaneous measurements of radon and other gases are new trials in recent studies. Contrary to soil/groundwater radon, we have not paid much attention to atmospheric radon before earthquakes. However, it might be possible to detect precursors in atmospheric radon before a large earthquake. In the next issues, we will discuss the details of the anomalous atmospheric radon data observed before the Hyogoken-Nanbu earthquake. (author)

  14. Reflection seismology systems for planetary geology : A feasibility study

    NARCIS (Netherlands)

    Batenburg, P.A.W.; Gill, E.K.A.; Drijkoningen, G.G.; Foing, B.H.; Toxopeus, G.

    2009-01-01

    A feasibility study is conducted to determine whether reflection seismology systems can be used for planetary geology research. The focus is on systems with up to 20,000 seismic detectors, such as used today in Earth geological research and energy companies. The study follows a top-down systems

  15. Evaluating Boy Scout Geology Education, A Pilot Study

    Science.gov (United States)

    Hintz, R. S.; Thomson, B.

    2008-12-01

    This study investigated geology knowledge acquisition by Boy Scouts through use of the Boy Scout Geology Merit Handbook. In this study, boys engaged in hands-on interactive learning following the requirements set forth in the Geology Merit Badge Handbook. The purposes of this study were to determine the amount of geology content knowledge engendered in adolescent males through the use of the Geology Merit Badge Handbook published by the Boy Scouts of America; to determine if single sex, activity oriented, free-choice learning programs can be effective in promoting knowledge development in young males; and to determine if boys participating in the Scouting program believed their participation helped them succeed in school. Members of a local Boy Scout Troop between the ages of 11 and 18 were invited to participate in a Geology Merit Badge program. Boys who did not already possess the badge were allowed to self-select participation. The boys' content knowledge of geology, rocks, and minerals was pre- and post-tested. Boys were interviewed about their school and Scouting experiences; whether they believed their Scouting experiences and work in Merit Badges contributed to their success in school. Contributing educational theories included single-sex education, informal education with free-choice learning, learning styles, hands-on activities, and the social cognitive theory concept of self-efficacy. Boys who completed this study seemed to possess a greater knowledge of geology than they obtained in school. If boys who complete the Boy Scout Geology Merit Badge receive additional geological training, their field experiences and knowledge acquired through this learning experience will be beneficial, and a basis for continued scaffolding of geologic knowledge.

  16. Synthetic Study on the Geological and Hydrogeological Model around KURT

    International Nuclear Information System (INIS)

    Park, Kyung Woo; Kim, Kyung Su; Koh, Yong Kwon; Choi, Jong Won

    2011-01-01

    To characterize the site specific properties of a study area for high-level radioactive waste disposal research in KAERI, the several geological investigations such as surface geological surveys and borehole drillings were carried out since 1997. Especially, KURT (KAERI Underground Research Tunnel) was constructed to understand the further study of geological environments in 2006. As a result, the first geological model of a study area was constructed by using the results of geological investigation. The objective of this research is to construct a hydrogeological model around KURT area on the basis of the geological model. Hydrogeological data which were obtained from in-situ hydraulic tests in the 9 boreholes were estimated to accomplish the objective. And, the hydrogeological properties of the 4 geological elements in the geological model, which were the subsurface weathering zone, the log angle fracture zone, the fracture zones and the bedrock were suggested. The hydrogeological model suggested in this study will be used as input parameters to carry out the groundwater flow modeling as a next step of the site characterization around KURT area

  17. Mathematical geology studies of deposit prospect types

    International Nuclear Information System (INIS)

    Liu Guangping

    1998-08-01

    Exact certainty prospect type of uranium deposit, not only can assure the quality of deposit prospects, but also increase economic benefits. Based on the standard of geological prospect of uranium deposit, the author introduces a method of Fuzzy Synthetical Comment for dividing prospect type of uranium deposit. The practical applications demonstrate that the regression accuracy, discriminated by Zadeh operator, of 15 known deposits is 100%

  18. New study reveals twice as many asteroids as previously believed

    Science.gov (United States)

    2002-05-01

    The ISO satellite Credits: ESA ISO An artist's impression of the ISO spacecraft. The ISO Deep Asteroid Search indicates that there are between 1.1 million and 1.9 million 'space rocks' larger than 1 kilometre in diameter in the so-called 'main asteroid belt', about twice as many as previously believed. However, astronomers think it is premature to revise current assessments of the risk of the Earth being hit by an asteroid. Despite being in our own Solar System, asteroids can be more difficult to study than very distant galaxies. With sizes of up to one thousand kilometres in diameter, the brightness of these rocky objects may vary considerably in just a few minutes. They move very quickly with respect to the stars - they have been dubbed 'vermin of the sky' because they often appear as trails on long exposure images. This elusiveness explains why their actual number and size distribution remains uncertain. Most of the almost 40,000 asteroids catalogued so far (1) orbit the Sun forming the 'main asteroid belt', between Mars and Jupiter, too far to pose any threat to Earth. However, space-watchers do keep a closer eye on another category of asteroids, the 'Near Earth Asteroids' or 'NEAs', which are those whose orbits cross, or are likely to cross, that of our planet. The ISO Deep Asteroid Search (IDAS), the first systematic search for these objects performed in infrared light, focused on main belt asteroids. Because it is impossible to simply point the telescope at the whole main belt and count, astronomers choose selected regions of the belt and then use a theoretical model to extrapolate the data to the whole belt. Edward Tedesco (TerraSystems, Inc., New Hampshire, United States) and François-Xavier Desert (Observatoire de Grenoble, France) observed their main belt selected areas in 1996 and 1997 with ESA's ISO. They found that in the middle region of the belt the density of asteroids was 160 asteroids larger than 1 kilometre per square degree - an area of the

  19. Application of remote sensing to the geological study of the alkaline complex region of Itatiaia. [Brazil

    Science.gov (United States)

    Dejesusparada, N. (Principal Investigator); Rodrigues, J. E.

    1980-01-01

    The methodology of remote sensing applied to geological study in a complex area was evaluated. Itatiaia was selected as a test area, which covers the alkaline massives and its precambrian basement. LANDSAT-MSS and radar mosaic of the RADAMBRASIL Project were used for photointerpretation. Previous geological works were consulted and many discrepancies in the distribution of stratigraphic units were found. Moreover, structural lineaments and talus deposits were clearly delineated.

  20. Geological Study of Monica Pintado mine. Florida town

    International Nuclear Information System (INIS)

    Medina, E.; Carrion, R.

    1988-01-01

    This work is about the geological study carried in Monica Pintado mine in Florida town by photointepretation - scale 1.20.000. In the area were found rocks granites, deep metamorfites and black granite

  1. Astronaut Neil Armstrong studies rock samples during geological field trip

    Science.gov (United States)

    1969-01-01

    Astronaut Neil Armstrong, commander of the Apollo 11 lunar landing mission, studies rock samples during a geological field trip to the Quitman Mountains area near the Fort Quitman ruins in far west Texas.

  2. Geologic studies of the Columbia Plateau: a status report

    International Nuclear Information System (INIS)

    Myers, C.W.; Price, S.M.

    1979-10-01

    The results of recent geologic studies of the Columbia Plateau, with emphasis on work completed under the Basalt Waste Isolation Project, Rockwell Hanford Operations, are summarized in this report. Geologic studies were performed mostly during the period from 1977 to 1979. The major objective of these studies was to examine the feasibility of using deep underground tunnels mined into Columbia River basalt beneath the Hanford Site for final storage of nuclear waste. The results are presented in four chapters: Introduction; Regional Geology; Pasco Basin Geology; and Seismicity and Tectonics. Results from surface mapping and remote sensing studies in the Washington State portion of the Columbia Plateau are presented in the Regional Geology chapter. Results from surface mapping, borehole studies, and geophysical surveys in the Pasco Basin are presented in the Pasco Basin Geology chapter. Results that relate to the tectonic stability of the Pasco Basin and Columbia Plateau and discussion of findings from earthquake monitoring in the region for the past ten years are summarized in the Seismicity and Tectonics chapter. A volume of Appendices is included. This volume contains a description of study tasks, a description of the methodology used in geophysical surveys the geophysical survey results, a summary of earthquake records in eastern Washington, a description of tectonic provinces, and a preliminary description of the regional tectonic setting of the Columbia Plateau

  3. Study of hydrogeological and engineering-geological conditions of deposits

    International Nuclear Information System (INIS)

    1985-01-01

    Methods for hydrogeological and engineering-geological studies are considered as a part of the complex works dUring eXploration of hydrogenic uranium deposits to develop them by Underground ieaching (UL). Problems are enumerated and peculiarities Of hydrogeologic and engipeering-geological works at different stages are outlined (prospeccing - evaluating works, preliminary and detailed survey). Attention is paid to boring and equipment for hydrogeological and engineering - geological boreholes. Testing-filtering works are described, the latter includes: evacuations, fulnesses ( forcings), and tests of fulness-evacuation. The problem on steady-state observations in boreholes and laboratory studies of rocks and underground waters is discussed. Geological and geophysical methods for evaluation of rock and ore filtering properties are presented. Necessity of hydrogeological zonation of deposits as applied to UL is marked

  4. Geologic studies in Alaska by the U.S. Geological Survey, 1992

    Science.gov (United States)

    Dusel-Bacon, Cynthia; Till, Alison B.

    1993-01-01

    This collection of 19 papers continues the annual series of U.S. Geological Survey reports on the geology of Alaska. The contributions, which include full-length Articles and shorter Geologic Notes, cover a broad range of topics including dune formation, stratigraphy, paleontology, isotopic dating, mineral resources, and tectonics. Articles, grouped under four regional headings, span nearly the entire State from the North Slope to southwestern, south-central, and southeastern Alaska (fig. 1).In the section on northern Alaska, Galloway and Carter use new data on dune morphology and radiocarbon ages from the western Arctic Coastal Plain to develop a late Holocene chronology of multiple episodes of dune stabilization and reactivation for the region. Their study has important implications for climatic changes in northern Alaska during the past 4,000 years. In two papers, Dumoulin and her coauthors describe lithofacies and conodont faunas of Carboniferous strata in the western Brooks Range, discuss depositional environments, and propose possible correlations and source areas for some of the strata. Schenk and Bird propose a preliminary division of the Lower Cretaceous stratigraphic section in the central part of the North Slope into depositional sequences. Aleinikoff and others present new U-Pb data for zircons from metaigneous rocks from the central Brooks Range. Karl and Mull, reacting to a proposal regarding terrane nomenclature for northern Alaska that was published in last year's Alaskan Studies Bulletin, provide a historical perspective of the evolution of terminology for tectonic units in the Brooks Range and present their own recommendations.

  5. Natural analogues: studies of geological processes relevant to radioactive waste disposal in deep geological repositories

    International Nuclear Information System (INIS)

    Russel, A.W.; Reijonen, H.M.; McKinley, I.G.

    2015-01-01

    The geological disposal of radioactive wastes is generally accepted to be the most practicable approach to handling the waste inventory built up from over 70 years accumulation of power production, research-medical-industrial and military wastes. Here, a brief overview of the approach to geological disposal is presented along with some information on repository design and the assessment of repository post-closure safety. One of the significant challenges for repository safety assessment is how to extrapolate the likely long-term (i.e. ten thousand to a million years) behaviour of the repository from the necessarily short term data from analytical laboratories and underground rock laboratories currently available. One approach, common to all fields of the geosciences, but also in such diverse fields as philosophy, biology, linguistics, law, etc., is to utilise the analogue argumentation methodology. For the specific case of radioactive waste management, the term 'natural analogue' has taken on a particular meaning associated with providing supporting arguments for a repository safety assessment. This approach is discussed here with a brief overview of how the study of natural (and, in particular, geological) systems can provide supporting information on the likely long-term evolution of a deep geological waste repository. The overall approach is discussed and some relevant examples are presented, including the use of uranium ore bodies to assess waste form stability, the investigation of native metals to define the longevity of waste containers and how natural clays can provide information on the stability of waste tunnel backfill material. (authors)

  6. Natural analogues: studies of geological processes relevant to radioactive waste disposal in deep geological repositories

    Energy Technology Data Exchange (ETDEWEB)

    Russel, A.W. [Bedrock Geosciences, Auenstein (Switzerland); Reijonen, H.M. [Saanio and Rickkola Oy, Helsinki (Finland); McKinley, I.G. [MCM Consulting, Baden-Daettwil (Switzerland)

    2015-06-15

    The geological disposal of radioactive wastes is generally accepted to be the most practicable approach to handling the waste inventory built up from over 70 years accumulation of power production, research-medical-industrial and military wastes. Here, a brief overview of the approach to geological disposal is presented along with some information on repository design and the assessment of repository post-closure safety. One of the significant challenges for repository safety assessment is how to extrapolate the likely long-term (i.e. ten thousand to a million years) behaviour of the repository from the necessarily short term data from analytical laboratories and underground rock laboratories currently available. One approach, common to all fields of the geosciences, but also in such diverse fields as philosophy, biology, linguistics, law, etc., is to utilise the analogue argumentation methodology. For the specific case of radioactive waste management, the term 'natural analogue' has taken on a particular meaning associated with providing supporting arguments for a repository safety assessment. This approach is discussed here with a brief overview of how the study of natural (and, in particular, geological) systems can provide supporting information on the likely long-term evolution of a deep geological waste repository. The overall approach is discussed and some relevant examples are presented, including the use of uranium ore bodies to assess waste form stability, the investigation of native metals to define the longevity of waste containers and how natural clays can provide information on the stability of waste tunnel backfill material. (authors)

  7. Geology - Background complementary studies. Forsmark modelling stage 2.2

    Energy Technology Data Exchange (ETDEWEB)

    Stephens, Michael B. [Geological Survey of Sweden, Uppsala (Sweden); Skagius, Kristina [Kemakta Konsult AB, Stockholm (Sweden)] (eds.)

    2007-09-15

    During Forsmark model stage 2.2, seven complementary geophysical and geological studies were initiated by the geological modelling team, in direct connection with and as a background support to the deterministic modelling of deformation zones. One of these studies involved a field control on the character of two low magnetic lineaments with NNE and NE trends inside the target volume. The interpretation of these lineaments formed one of the late deliveries to SKB that took place after the data freeze for model stage 2.2 and during the initial stage of the modelling work. Six studies involved a revised processing and analysis of reflection seismic, refraction seismic and selected oriented borehole radar data, all of which had been presented earlier in connection with the site investigation programme. A prime aim of all these studies was to provide a better understanding of the geological significance of indirect geophysical data to the geological modelling team. Such essential interpretative work was lacking in the material acquired in connection with the site investigation programme. The results of these background complementary studies are published together in this report. The titles and authors of the seven background complementary studies are presented below. Summaries of the results of each study, with a focus on the implications for the geological modelling of deformation zones, are presented in the master geological report, SKB-R--07-45. The sections in the master report, where reference is made to each background complementary study and where the summaries are placed, are also provided. The individual reports are listed in the order that they are referred to in the master geological report and as they appear in this report. 1. Scan line fracture mapping and magnetic susceptibility measurements across two low magnetic lineaments with NNE and NE trend, Forsmark. Jesper Petersson, Ulf B. Andersson and Johan Berglund. 2. Integrated interpretation of surface and

  8. Sorption studies of radioelements on geological materials

    International Nuclear Information System (INIS)

    Berry, John A.; Yui, Mikazu; Kitamura, Akira

    2007-11-01

    Batch sorption experiments have been carried out to study the sorption of uranium, technetium, curium, neptunium, actinium, protactinium, polonium, americium and plutonium onto bentonite, granodiorite and tuff. Mathematical modelling using the HARPHRQ program and the HATCHES database was carried out to predict the speciation of uranium and technetium in the equilibrated seawater, and neptunium, americium and plutonium in the rock equilibrated water. Review of the literature for thermodynamic data for curium, actinium, protactinium and polonium was carried out. Where sufficient data were available, predictions of the speciation and solubility were made. This report is a summary report of the experimental work conducted by AEA Technology during April 1991-March 1998, and the main results have been presented at Material Research Society Symposium Proceedings and published as proceedings of them. (author)

  9. Preliminary study on geology, mineral potential and characteristics ...

    African Journals Online (AJOL)

    Preliminary study on geology, mineral potential and characteristics of hot springs from Dallol area, Afar rift, northeastern Ethiopia: Implications for natural ... Although low, the up to 902 ppm TOC concentrations in the hydrothermal fluids could suggest the presence of hydrocarbon containing rocks at depth and/or fluid mixing ...

  10. The JABE project: geological studies with a backpack drilling system.

    Science.gov (United States)

    Jago, Alban; van Vynckt, Delphine; de Crombrugghe, Guerric; Denies, Jonathan; Le Maire, Victor; Reydams, Marc

    Besides those geological surveys, we will also study how this drilling system could be used to fix some installations on the ground. As part of the JUMP mission we are also developing a cosmic ray detector and a radio telescope. Those experiments have to be securely fixed and this is what we will try to do using the backpack drilling system and EVA's suits. We shall report on the science and technical results, and implications for Earth-Mars compar-ative studies.

  11. Study on geological environment model using geostatistics method

    International Nuclear Information System (INIS)

    Honda, Makoto; Suzuki, Makoto; Sakurai, Hideyuki; Iwasa, Kengo; Matsui, Hiroya

    2005-03-01

    The purpose of this study is to develop the geostatistical procedure for modeling geological environments and to evaluate the quantitative relationship between the amount of information and the reliability of the model using the data sets obtained in the surface-based investigation phase (Phase 1) of the Horonobe Underground Research Laboratory Project. This study lasts for three years from FY2004 to FY2006 and this report includes the research in FY2005 as the second year of three-year study. In FY2005 research, the hydrogeological model was built as well as FY2004 research using the data obtained from the deep boreholes (HDB-6, 7 and 8) and the ground magnetotelluric (AMT) survey which were executed in FY2004 in addition to the data sets used in the first year of study. Above all, the relationship between the amount of information and the reliability of the model was demonstrated through a comparison of the models at each step which corresponds to the investigation stage in each FY. Furthermore, the statistical test was applied for detecting the difference of basic statistics of various data due to geological features with a view to taking the geological information into the modeling procedures. (author)

  12. Study on high-level waste geological disposal metadata model

    International Nuclear Information System (INIS)

    Ding Xiaobin; Wang Changhong; Zhu Hehua; Li Xiaojun

    2008-01-01

    This paper expatiated the concept of metadata and its researches within china and abroad, then explain why start the study on the metadata model of high-level nuclear waste deep geological disposal project. As reference to GML, the author first set up DML under the framework of digital underground space engineering. Based on DML, a standardized metadata employed in high-level nuclear waste deep geological disposal project is presented. Then, a Metadata Model with the utilization of internet is put forward. With the standardized data and CSW services, this model may solve the problem in the data sharing and exchanging of different data form A metadata editor is build up in order to search and maintain metadata based on this model. (authors)

  13. 40 CFR 152.93 - Citation of a previously submitted valid study.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Citation of a previously submitted... Data Submitters' Rights § 152.93 Citation of a previously submitted valid study. An applicant may... the citation is necessary. (b) Study previously submitted by another person. If the applicant is not...

  14. Study geology and uranium mineralization of ririt-amir engkala - tiga dara sector West Kalimantan

    International Nuclear Information System (INIS)

    Bambang Soetopo

    2009-01-01

    The results of previous research from Ririt, Amir Engkala, Tiga Dara sector which consist of geology, geophysics and drilling data show that all of the areas has similar in geology and Uranium mineralization. The purpose of this study is to know the relationship between geological condition and Uranium mineralization in Ririt, Amir Engkala and Tiga Dara sector. In general the geology of Ririt and Amir Engkala is similar with Tiga Dara sector. Those areas consist of tourmaline quartzite, muscovite quartzite, meta ignimbrite, biotite quartz schist, muscovite quartz schist, and micro diorite. The direction of the stratification is NE - SW and dipping to SE and the direction of the stochasticity is W - E and dipping to N. The dextral faults have WNW-ESE and NNE - SSW trends, while the sinistral one is WSW - ENE direction. There are also a thrust fault and a normal fault with WSW-ESE and NW-SE striking respectively. Uranium mineralization as a uraninite fill in the stochasticity and fracture N2600-30° E37°-59° in orientation which associated with magnetite, chalcopyrite, pyrite, arsenopyrite,. rutile, ilmenite, tourmaline and quartz. Radiometric value of Uranium mineralization is in the range of 500-15.000 c/s. The mineral association and the present of calcite, gypsum and quartz veins suggest that Uranium mineralization was resulted by hydrothermal magmatic processes. (author)

  15. Geologic study of Kettle dome, northeast Washington. Final report

    International Nuclear Information System (INIS)

    1980-10-01

    This geologic study of Kettle dome, northeast Washington, encompasses an area of approximately 800 square miles (2048 sq km). The evaluation of uranium occurrences associated with the igneous and metamorphic rocks of the dome and the determination of the relationship between uranium mineralization and stratigraphic, structural, and metamorphic features of the dome are the principal objectives. Evaluation of the validity of a gneiss dome model is a specific objective. The principal sources of data are detailed geologic mapping, surface radiometric surveys, and chemical analyses of rock samples. Uranium mineralization is directly related to the presence of pegmatite dikes and sills in biotite gneiss and amphibolite. Other characteristics of the uranium occurrences include the associated migmatization and high-grade metamorphism of wallrock adjacent to the pegmatite and the abrupt decrease in uranium mineralization at the pegmatite-gneiss contact. Subtle chemical characteristics found in mineralized pegmatites include: (1) U increase as K 2 O increases, (2) U decreases as Na 2 O increases, and (3) U increases as CaO increases at CaO values above 3.8%. The concentration of uranium occurrences in biotite gneiss and amphibolite units results from the preferential intrusion of pegmitites into these well-foliated rocks. Structural zones of weakness along dome margins permit intrusive and migmatitic activity to affect higher structural levels of the dome complex. As a result, uranium mineralization is localized along dome margins. The uranium occurrences in the Kettle dome area are classified as pegmatitic. Sufficient geologic similarities exist between Kettle dome and the Rossing uranium deposit to propose the existence of economic uranium targets within Kettle dome

  16. Parametric study of geohydrologic performance characteristics for geologic waste repositories

    International Nuclear Information System (INIS)

    Bailey, C.E.; Marine, I.W.

    1980-11-01

    One of the major objectives of the National Waste Terminal Storage Program is to identify potential geologic sites for storage and isolation of radioactive waste (and possibly irradiated fuel). Potential sites for the storage and isolation of radioactive waste or spent fuel in a geologic rock unit are being carefully evaluated to ensure that radionuclides from the stored waste or fuel will never appear in the biosphere in amounts that would constitute a hazard to the health and safety of the public. The objective of this report is to quantify and present in graphical form the effects of significant geohydrologic and other performance characteristics that would influence the movement of radionuclides from a storage site in a rock unit to the biosphere. The effort in this study was focused on transport by groundwater because that is the most likely method of radionuclide escape. Graphs of the major performance characteristics that influence the transport of radionuclides from a repository to the biosphere by groundwater are presented. The major characteristics addressed are radioactive decay, leach rate, hydraulic conductivity, porosity, groundwater gradient, hydrodynamic dispersion, ion exchange, and distance to the biosphere. These major performance characteristics are combind with each other and with the results of certain other combinations and presented in graphical form to provide the interrelationships of values measured during field studies. The graphical form of presentation should be useful in the screening process of site selection. An appendix illustrates the use of these graphs to assess the suitability of a site

  17. Summary of Previous Chamber or Controlled Anthrax Studies and Recommendations for Possible Additional Studies

    Energy Technology Data Exchange (ETDEWEB)

    Piepel, Gregory F.; Amidan, Brett G.; Morrow, Jayne B.

    2010-12-29

    This report and an associated Excel file(a) summarizes the investigations and results of previous chamber and controlled studies(b) to characterize the performance of methods for collecting, storing and/or transporting, extracting, and analyzing samples from surfaces contaminated by Bacillus anthracis (BA) or related simulants. This report and the Excel are the joint work of the Pacific Northwest National Laboratory (PNNL) and the National Institute of Standards and Technology (NIST) for the Department of Homeland Security, Science and Technology Directorate. The report was originally released as PNNL-SA-69338, Rev. 0 in November 2009 with limited distribution, but was subsequently cleared for release with unlimited distribution in this Rev. 1. Only minor changes were made to Rev. 0 to yield Rev. 1. A more substantial update (including summarizing data from other studies and more condensed summary tables of data) is underway

  18. Geologic Interpretation of Data Sets Collected by Planetary Analog Geology Traverses and by Standard Geologic Field Mapping. Part 1; A Comparison Study

    Science.gov (United States)

    Eppler, Dean B.; Bleacher, Jacob F.; Evans, Cynthia A.; Feng, Wanda; Gruener, John; Hurwitz, Debra M.; Skinner, J. A., Jr.; Whitson, Peggy; Janoiko, Barbara

    2013-01-01

    Geologic maps integrate the distributions, contacts, and compositions of rock and sediment bodies as a means to interpret local to regional formative histories. Applying terrestrial mapping techniques to other planets is challenging because data is collected primarily by orbiting instruments, with infrequent, spatiallylimited in situ human and robotic exploration. Although geologic maps developed using remote data sets and limited "Apollo-style" field access likely contain inaccuracies, the magnitude, type, and occurrence of these are only marginally understood. This project evaluates the interpretative and cartographic accuracy of both field- and remote-based mapping approaches by comparing two 1:24,000 scale geologic maps of the San Francisco Volcanic Field (SFVF), north-central Arizona. The first map is based on traditional field mapping techniques, while the second is based on remote data sets, augmented with limited field observations collected during NASA Desert Research & Technology Studies (RATS) 2010 exercises. The RATS mission used Apollo-style methods not only for pre-mission traverse planning but also to conduct geologic sampling as part of science operation tests. Cross-comparison demonstrates that the Apollo-style map identifies many of the same rock units and determines a similar broad history as the field-based map. However, field mapping techniques allow markedly improved discrimination of map units, particularly unconsolidated surficial deposits, and recognize a more complex eruptive history than was possible using Apollo-style data. Further, the distribution of unconsolidated surface units was more obvious in the remote sensing data to the field team after conducting the fieldwork. The study raises questions about the most effective approach to balancing mission costs with the rate of knowledge capture, suggesting that there is an inflection point in the "knowledge capture curve" beyond which additional resource investment yields progressively

  19. A geological reconnaissance study of the Lac du Bonnet batholith

    International Nuclear Information System (INIS)

    Tammemagi, H.Y.; Kerford, P.S.; Requeima, J.C.; Temple, C.A.

    1980-02-01

    A geological reconnaissance survey was carried out of the Lac du Bonnet batholith, southeastern Manitoba, as part of the concept verification phase of the nuclear fuel waste disposal program for Canada. This report summarizes available geological information, presents the results of field mapping and discusses the geochemical analyses of rock samples. The geological and structural aspects of the batholith are described as well as its regional setting and possible genesis. (auth)

  20. Geotechnical support and topical studies for nuclear waste geologic repositories

    International Nuclear Information System (INIS)

    1989-01-01

    The present report lists the technical reviews and comments made during the fiscal year 1988 and summarizes the technical progress of the topical studies. In the area of technical assistance, there were numerous activities detailed in the next section. These included 24 geotechnical support activities, including reviews of 6 Study Plans (SP) and participation in 6 SP Review Workshops, review of one whole document Site Characterization Plan (SCP) and participation in the Assembled Document SCP Review Workshops by 6 LBL reviewers; the hosting of a DOE program review, the rewriting of the project statement of work, 2 trips to technical and planning meetings; preparation of proposed work statements for two new topics for DOE, and 5 instances of technical assistance to DOE. These activities are described in a Table in the following section entitled ''Geoscience Technical Support for Nuclear Waste Geologic Repositories.''

  1. Geotechnical support and topical studies for nuclear waste geologic repositories

    Energy Technology Data Exchange (ETDEWEB)

    1989-01-01

    The present report lists the technical reviews and comments made during the fiscal year 1988 and summarizes the technical progress of the topical studies. In the area of technical assistance, there were numerous activities detailed in the next section. These included 24 geotechnical support activities, including reviews of 6 Study Plans (SP) and participation in 6 SP Review Workshops, review of one whole document Site Characterization Plan (SCP) and participation in the Assembled Document SCP Review Workshops by 6 LBL reviewers; the hosting of a DOE program review, the rewriting of the project statement of work, 2 trips to technical and planning meetings; preparation of proposed work statements for two new topics for DOE, and 5 instances of technical assistance to DOE. These activities are described in a Table in the following section entitled Geoscience Technical Support for Nuclear Waste Geologic Repositories.''

  2. Geological, geochemical, and geophysical studies by the U.S. Geological Survey in Big Bend National Park, Texas

    Science.gov (United States)

    Page, W.R.; Turner, K.J.; Bohannon, R.G.; Berry, M.E.; Williams, V.S.; Miggins, D.P.; Ren, M.; Anthony, E.Y.; Morgan, L.A.; Shanks, P.W.C.; Gray, J. E.; Theodorakos, P.M.; Krabbenhoft, D. P.; Manning, A.H.; Gemery-Hill, P. A.; Hellgren, E.C.; Stricker, C.A.; Onorato, D.P.; Finn, C.A.; Anderson, E.; Gray, J. E.; Page, W.R.

    2008-01-01

    Big Bend National Park (BBNP), Tex., covers 801,163 acres (3,242 km2) and was established in 1944 through a transfer of land from the State of Texas to the United States. The park is located along a 118-mile (190-km) stretch of the Rio Grande at the United States-Mexico border. The park is in the Chihuahuan Desert, an ecosystem with high mountain ranges and basin environments containing a wide variety of native plants and animals, including more than 1,200 species of plants, more than 450 species of birds, 56 species of reptiles, and 75 species of mammals. In addition, the geology of BBNP, which varies widely from high mountains to broad open lowland basins, also enhances the beauty of the park. For example, the park contains the Chisos Mountains, which are dominantly composed of thick outcrops of Tertiary extrusive and intrusive igneous rocks that reach an altitude of 7,832 ft (2,387 m) and are considered the southernmost mountain range in the United States. Geologic features in BBNP provide opportunities to study the formation of mineral deposits and their environmental effects; the origin and formation of sedimentary and igneous rocks; Paleozoic, Mesozoic, and Cenozoic fossils; and surface and ground water resources. Mineral deposits in and around BBNP contain commodities such as mercury (Hg), uranium (U), and fluorine (F), but of these, the only significant mining has been for Hg. Because of the biological and geological diversity of BBNP, more than 350,000 tourists visit the park each year. The U.S. Geological Survey (USGS) has been investigating a number of broad and diverse geologic, geochemical, and geophysical topics in BBNP to provide fundamental information needed by the National Park Service (NPS) to address resource management goals in this park. Scientists from the USGS Mineral Resources and National Cooperative Geologic Mapping Programs have been working cooperatively with the NPS and several universities on several research studies within BBNP

  3. Geological Study Collection of the Mercury Mine in Idrija

    NARCIS (Netherlands)

    Car, J.; Rezun, B.

    2004-01-01

    The collection and classification of various geological samples has a long tradition in the Idrija Mercury Mine. In the second half of the 19th century geological collection was prepared and arranged by M.V. Lipold. In 1956, a rich petrographic-palaeontological collection was created at the

  4. Influence Of Geology On Pavement Performance: A Case Study Of ...

    African Journals Online (AJOL)

    The Shagamu-Benin city Road, a major link highway to the commercial capital of Nigeria in southwestern Nigeria is oriented approximately east-west and traverse geologic formations with extremely variable engineering properties. Field and laboratory investigations which involved geologic mapping, auger boring, ...

  5. Geologic studies in the Sierra de Pena Blanca, Chihuahua, Mexico

    Science.gov (United States)

    Reyes-Cortes, Ignacio Alfonso

    The Sierra del Cuervo has been endowed with uranium mineralization, which has attracted many geological studies, and recently the author was part of a team with the goal of selecting a site of a radioactive waste repository. The first part of the work adds to the regional framework of stratigraphy and tectonics of the area. It includes the idea of a pull apart basin development, which justifies the local great thickness of the Cuervo Formation. It includes the regional structural frame work and the composite stratigraphic column of the Chihuahua Trough and the equivalent Cretaceous Mexican Sea. The general geologic features of the NE part of the Sierra del Cuervo are described, which include the folded ignimbrites and limestones in that area; the irregular large thicknesses of the Cuervo Formation; and the western vergence of the main folding within the area. Sanidine phenocrystals gave ages of 54.2 Ma and 51.8 Ma ± 2.3 Ma. This is the first time these dates have been reported in print. This age indicates a time before the folded structures which outcrop in the area, and 44 Ma is a date after the Cuervo Formation was folded. The Hidalgoan orogeny cycle affected the rocks between this lapse of time. Since then the area has been partially affected by three tensional overlapped stages, which resulted in the actual Basin and Range physiography. The jarosite related to the tectonic activity mineralization has been dated by the Ar-Ar method and yields an age of 9.8 Ma. This is the first report of a date of mineralization timing at Pena Blanca Uranium District in the Sierra del Cuervo. These are some of the frame work features that justify the allocation of a radioactive waste repository in the Sierra del Cuervo. An alluvial fan system within the Boquilla Colorada microbasin was selected as the best target for more detailed site assessment. The study also included the measurement of the alluvium thicknesses by geoelectric soundings; studies of petrography and weathered

  6. Geologic and remote sensing studies of Rima Mozart

    Science.gov (United States)

    Coombs, Cassandra R.; Hawke, B. Ray; Wilson, Lionel

    1988-01-01

    Geologic, photographic, and remote sensing data on Rima Mozart are analyzed to study the processes responsible for the formation of lunar sinuous rilles. The results show that it is unlikely that a complete lava tube could have existed along the Rima Mozart rille. A total eruptive volume of 6372 cu km has been determined for an open channel or tube with an eruption rate of about 80,000 cu m/s and a duration of 947 days. Near-infrared spectral reflectance data and 2.8-cm and 70-cm radar observations indicate that volcanic activity was responsible for the formation of the rille and that pyroclastic deposits are present around Kathleen and Ann as well as at the base of the Apennines.

  7. Geological reconnaissance and chronologic studies. Technical report No. 33

    International Nuclear Information System (INIS)

    Davis, J.

    1983-03-01

    There are several possible scenarios by which a radioactive waste storage facility in the unsaturated zone could be compromised; among them erosion, water table rise, or downward percolation of water. In order to assess these risks, the geologic and climatic events of the past few million years can be used to project the future of the unsaturated deposits. Geologic reconnaissance on and around the NTS was undertaken to identify specific evidence of depositional, erosional, and hydrologic events, as well as to develop an understanding of the timing of these events. Several kinds of evidence were noted and studied: layers or volcanic ash in the basin-fill sediments were discovered and dated at 11 to 5 m.y. old, showing the modern valleys and ranges are at least 11 m.y. old. Exposure of these ash layers by erosion has taken 5 m.y., implying that additional millions of years must pass before modern closed basins on the NTS are eroded. Detailed study of young sediments in Las Vegas Valley suggest that water tables stood at 926 m as recently as 14,000 y ago. To the northeast or the NTS, sediments in basin bottoms also reflect high water tables until about 7000 y ago, but sediments on the NTS proper do not show this effect during the last 700,000 y. The observed relation between erosion due to downwearing or mountain ranges and infilling of valleys suggests that these processes continue, only the uppermost parts of present alluvial fans will be eroded

  8. GIS-technologies as a mechanism to study geological structures

    Science.gov (United States)

    Sharapatov, Abish

    2014-05-01

    Specialized GIS-technologies allow creating multi-parameter models, completing multi-criteria optimisation tasks, and issues of geological profile forecasts using miscellaneous data. Pictorial and attributive geological and geophysical information collected to create GIS database is supplemented by the ERS (Earth's Remote Sensing) data, air spectrometry, space images, and topographic data. Among the important tasks are as follows: a unification of initial geological, geophysical and other types of information on a tectonic position, rock classification and stratigraphic scale; topographic bases (various projectures, scales); the levels of detail and exhaustibility; colors and symbols of legends; data structures and their correlation; units of measurement of physical quantities, and attribute systems of descriptions. Methods of the geological environment investigation using GIS-technology are based on a principle of the research target analogy with a standard. A similarity ratio is quantitative estimate. A geological forecast model is formed by structuring of geological information based on detailed analysis and aggregation of geological and formal knowledge bases on standard targets. Development of a bank of models of the analyzed geological structures of various range, ore-bearing features described by numerous prospecting indicators is the way to aggregate geological knowledge. The south terrain of the Valerianovskaya structure-facies zone (SFZ) of the Torgai paleo-rift structure covered with thick Mesozoic and Cenozoic rocks up to 2,000m is considered a so-called training ground for the development of GIS-technology. Parameters of known magnetite deposits located in the north of the SFZ (Sarybaiskoye, Sokolovskoye, etc.) are used to create the standard model. A meaning of the job implemented involves the following: - A goal-seeking nature of the research being performed and integration of the geological, geo-physical and other data (in many cases, efforts of the

  9. Study on the Geological Structure around KURT Using a Deep Borehole Investigation

    International Nuclear Information System (INIS)

    Park, Kyung Woo; Kim, Kyung Su; Koh, Yong Kwon; Choi, Jong Won

    2010-01-01

    To characterize geological features in study area for high-level radioactive waste disposal research, KAERI (Korea Atomic Energy Research Institute) has been performing the several geological investigations such as geophysical surveys and borehole drilling since 1997. Especially, the KURT (KAERI Underground Research Tunnel) constructed to understand the deep geological environments in 2006. Recently, the deep borehole of 500 m depths was drilled to confirm and validate the geological model at the left research module of the KURT. The objective of this research was to identify the geological structures around KURT using the data obtained from the deep borehole investigation. To achieve the purpose, several geological investigations such as geophysical and borehole fracture surveys were carried out simultaneously. As a result, 7 fracture zones were identified in deep borehole located in the KURT. As one of important parts of site characterization on KURT area, the results will be used to revise the geological model of the study area

  10. Identification of multidrug resistance in previously treated tuberculosis patients: a mixed methods study in Cambodia

    Science.gov (United States)

    Royce, S; Khann, S; Yadav, RP; Mao, ET; Cattamanchi, A; Sam, S; Handley, MA

    2014-01-01

    SUMMARY Setting Previously treated tuberculosis (TB) patients are a priority for drug susceptibility testing (DST) to identify cases with multidrug resistance (MDR). In Cambodia, a recent study found that only one-third of smear-positive previously treated patients had DST results. Objective To quantify the gaps in detecting MDR in previously treated TB patients in Cambodia, and describe health workers’ perspectives on barriers, facilitators and potential interventions. Design We analyzed case notifications in Cambodia (2004–2012) and conducted semi-structured interviews with key stakeholders Results The proportion of previously treated notifications varied significantly across provinces 2010–12, in the context of longer term trends of decreasing relapse and increasing “other” retreatment notifications. Correct classification of patients’ TB treatment history and ensuring specimens from previously-treated patients are collected and reach the laboratory could nearly double the number of detected MDR-TB cases. Identified barriers include patients’ reluctance to disclose and staff difficulty eliciting treatment history, partly due to availability of streptomycin only in hospitals. Facilitators include trained health workers, collection of sputum for DST even if previously treated patients are not taking streptomycin, streamlining sputum transportation and promptly reporting results. Conclusion Improved monitoring, supportive supervision, and correctly classifying previously treated patients are essential for improving detection of MDR-TB. PMID:25299861

  11. Matched cohort study of external cephalic version in women with previous cesarean delivery.

    Science.gov (United States)

    Keepanasseril, Anish; Anand, Keerthana; Soundara Raghavan, Subrahmanian

    2017-07-01

    To evaluate the efficacy and safety of external cephalic version (ECV) among women with previous cesarean delivery. A retrospective study was conducted using data for women with previous cesarean delivery and breech presentation who underwent ECV at or after 36 weeks of pregnancy during 2011-2016. For every case, two multiparous women without previous cesarean delivery who underwent ECV and were matched for age and pregnancy duration were included. Characteristics and outcomes were compared between groups. ECV was successful for 32 (84.2%) of 38 women with previous cesarean delivery and 62 (81.6%) in the control group (P=0.728). Multivariate regression analysis confirmed that previous cesarean was not associated with ECV success (odds ratio 1.89, 95% confidence interval 0.19-18.47; P=0.244). Successful vaginal delivery after successful ECV was reported for 19 (59.4%) women in the previous cesarean delivery group and 52 (83.9%) in the control group (Pcesarean delivery. To avoid a repeat cesarean delivery, ECV can be offered to women with breech presentation and previous cesarean delivery who are otherwise eligible for a trial of labor. © 2017 International Federation of Gynecology and Obstetrics.

  12. A study on site characterization of the deep geological environment around KURT

    International Nuclear Information System (INIS)

    Park, Kw; Kim, Gy; Koh, Yk; Kim, Ks; Choi, Jw

    2009-01-01

    KURT (KAERI Underground Research Tunnel) is a small scale research tunnel which was constructed from 2005 to 2006 at Korea Atomic Energy Research Institute (KAERI). To understand the deep geological environment around KURT area, the surface geological surveys such as lineaments analysis and geophysical survey and borehole investigation were performed. For this study, a 3 dimensional geological model has been constructed using the surface and borehole geological data. The regional lineaments were determined using a topographical map and the surface geophysical survey data were collected for the geological model. In addition, statistical methods were applied to fracture data from borehole televiewer loggings to identify fracture zones in boreholes. For a hydro geological modeling, fixed interval hydraulic tests were carried out for all boreholes. The results of the hydraulic tests were analyzed and classified by the fracture zone data of geological model. At result, the hydrogeological elements were decided and the properties of each element were assessed around the KURT area

  13. Geotechnical support and topical studies for nuclear waste geologic repositories

    International Nuclear Information System (INIS)

    1990-12-01

    This multidisciplinary project was initiated in fiscal year 1986. It comprises two major interrelated tasks, technical assistance and topical studies. The present report lists the technical reviews and comments made during the fiscal year 1989 and summarizes the technical progress of the topical studies. The major task was a study of the mechanical, hydraulic, geophysical and geochemical properties of fractures in geologic rock masses. In the area of technical assistance, there were a total of 30 geotechnical support activities, including reviews of 15 study plans (SP) and participation in 5 SP Review Workshops; in-depth multidisciplinary review of 5 Exploratory Shaft Facility (ESF) Study Plans and presentation of results to DOE; preparation and revision of a white paper and proposed work statement on preclosure monitoring and performance confirmation as an outgrowth of a request made by DOE to LBL; the hosting of a DOE program review; with DOE's encouragement, preparation of 8 papers for the International High-Level Radioactive Waste Management Conference to be held in April, 1990 in Las Vegas, Nevada; and 5 instances of general technical assistance to DOE

  14. Study of microorganisms present in deep geologic formations

    International Nuclear Information System (INIS)

    Camus, H.; Lion, R.; Bianchi, A.; Garcin, J.

    1987-01-01

    This work has been executed in the scope of the studies on high activity radioactive wastes storage in deep geological environments. The authors make reference to an as complete as possible literature on the existence of microorganisms in those environments or under similar conditions. Then they describe the equipment and methods they have implemented to perform their study of the populations present in three deep-reaching drill-holes in Auriat (France), Mol (Belgique) and Troon (Great Britain). The results of the study exhibit the presence of a certain biological activity, well adapted to that particular life environment. Strains appear to be very varied from the taxonomic point of view and seemingly show an important potential of mineral alteration when provided with an adequate source of energy. Complementary studies, using advanced techniques such as those employed during the work forming the basis of this paper, seem necessary for a more accurate evaluation of long-term risks of perturbation of a deep storage site [fr

  15. New approaches in geological studies of tsunami deposits

    Science.gov (United States)

    Szczucinski, Witold

    2017-04-01

    During the last dozen of years tsunamis have appeared to be the most disastrous natural process worldwide. The dramatic, large tsunamis on Boxing Day, 2004 in the Indian Ocean and on March 11, 2011 offshore Japan caused catastrophes listed as the worst in terms of the number of victims and the economic losses, respectively. In the aftermath, they have become a topic of high public and scientific interest. The record of past tsunamis, mainly in form of tsunami deposits, is often the only way to identify tsunami risk at a particular coast due to relatively low frequency of their occurrence. The identification of paleotsunami deposits is often difficult mainly because the tsunami deposits are represented by various sediment types, may be similar to storm deposits or altered by post-depositional processes. There is no simple universal diagnostic set of criteria that can be applied to interpret tsunami deposits with certainty. Thus, there is a need to develop new methods, which would enhance 'classical', mainly sedimentological and stratigraphic approach. The objective of the present contribution is to show recent progress and application of new approaches including geochemistry (Chagué-Goff et al. 2017) and paleogenetics (Szczuciński et al. 2016) in studies of geological impacts of recent tsunamis from various geographical regions, namely in monsoonal-tropical, temperate and polar zones. It is mainly based on own studies of coastal zones affected by 2004 Indian Ocean Tsunami in Thailand, 2011 Tohoku-oki tsunami and older paleotsunamis in Japan, catastrophic saltwater inundations at the coasts of Baltic Sea and 2000 landslide-generated tsunami in Vaigat Strait (west Greenland). The study was partly funded by Polish National Science Centre grant No. 2011/01/B/ST10/01553. Chagué-Goff C., Szczuciński W., Shinozaki T., 2017. Applications of geochemistry in tsunami research: A review. Earth-Science Reviews 165: 203-244. Szczuciński W., Pawłowska J., Lejzerowicz F

  16. Developing Reading Comprehension through Metacognitive Strategies: A Review of Previous Studies

    Science.gov (United States)

    Channa, Mansoor Ahmed; Nordin, Zaimuariffudin Shukri; Siming, Insaf Ali; Chandio, Ali Asgher; Koondher, Mansoor Ali

    2015-01-01

    This paper has reviewed the previous studies on metacognitive strategies based on planning, monitoring, and evaluating in order to develop reading comprehension. The main purpose of this review in metacognition, and reading domain is to help readers to enhance their capabilities and power reading through these strategies. The researchers reviewed…

  17. Study of some physical aspects previous to design of an exponential experiment

    International Nuclear Information System (INIS)

    Caro, R.; Francisco, J. L. de

    1961-01-01

    This report presents the theoretical study of some physical aspects previous to the design of an exponential facility. The are: Fast and slow flux distribution in the multiplicative medium and in the thermal column, slowing down in the thermal column, geometrical distribution and minimum needed intensity of sources access channels and perturbations produced by possible variations in its position and intensity. (Author) 4 refs

  18. Study of functional-performance deficits in athletes with previous ankle sprains

    Directory of Open Access Journals (Sweden)

    hamid Babaee

    2008-04-01

    Full Text Available Abstract Background: Despite the importance of functional-performance deficits in athletes with history of ankle sprain few, studies have been carried out in this area. The aim of this research was to study relationship between previous ankle sprains and functional-performance deficits in athletes. Materials and methods: The subjects were 40 professional athletes selected through random sampling among volunteer participants in soccer, basketball, volleyball and handball teams of Lorestan province. The subjects were divided into 2 groups: Injured group (athletes with previous ankle sprains and healthy group (athletes without previous ankle sprains. In this descriptive study we used Functional-performance tests (figure 8 hop test and side hop test to determine ankle deficits and limitations. They participated in figure 8 hop test including hopping in 8 shape course with the length of 5 meters and side hop test including 10 side hop repetitions in course with the length of 30 centimeters. Time were recorded via stopwatch. Results: After data gathering and assessing information distributions, Pearson correlation was used to assess relationships, and independent T test to assess differences between variables. Finally the results showed that there is a significant relationship between previous ankle sprains and functional-performance deficits in the athletes. Conclusion: The athletes who had previous ankle sprains indicated functional-performance deficits more than healthy athletes in completion of mentioned functional-performance tests. The functional-performance tests (figure 8 hop test and side hop test are sensitive and suitable to assess and detect functional-performance deficits in athletes. Therefore we can use the figure 8 hop and side hop tests for goals such as prevention, assessment and rehabilitation of ankle sprains without spending too much money and time.

  19. Previous treatment influences fingolimod efficacy in relapsing-remitting multiple sclerosis: results from an observational study.

    Science.gov (United States)

    Baldi, Eleonora; Guareschi, Angelica; Vitetta, Francesca; Senesi, Caterina; Curti, Erica; Montepietra, Sara; Simone, Anna Maria; Immovilli, Paolo; Caniatti, Luisa; Tola, Maria Rosaria; Pesci, Ilaria; Montanari, Enrico; Sola, Patrizia; Granella, Franco; Motti, Luisa; Ferraro, Diana

    2014-09-01

    Fingolimod (FTY) is licensed as a disease-modifying treatment in highly active relapsing-remitting multiple sclerosis. The aim of the study was to evaluate the efficacy and safety of FTY in a real-life setting and to explore the possible role of clinical and MRI parameters, including previous treatment type, in predicting its efficacy. Clinical and MRI data was collected on 127 patients assigned to treatment with FTY in six multiple sclerosis centers in Emilia-Romagna, Italy, between August 2011 and June 2013. During a mean follow-up period of 10 months (range 1-22), we observed a total of 47 relapses in 39 patients (30.7%); new T2 lesions or gadolinium-enhancing (Gd+) lesions were present at follow-up MRI in 32/71 patients (45%). Expanded disability status scale (EDSS) at the end of the follow-up period was not different when compared to the baseline EDSS. Serious adverse events occurred in three patients (2.4%). A higher proportion of patients previously treated with natalizumab showed clinical (41%) or MRI activity (54%). Previous treatment with natalizumab increased the risk of a relapse within 30 days (versus immunomodulatory drugs; OR: 4.3; p = 0.011) and at survival analysis (versus remaining patients; HR: 1.9; p = 0.046). Study limitations include a small population sample, a short observation period with variable timing of follow-up MRI and different baseline characteristics of patients previously treated with natalizumab compared to those treated with immunomodulatory drugs. This study confirms the efficacy of FTY in reducing relapse rate in patients previously treated with immunomodulatory drugs, while it seems to be less effective in patients discontinuing natalizumab. Due to the short duration of follow-up it is not possible to evaluate disability progression; however, no difference was observed between the groups.

  20. Previous infection and the risk of ischaemic stroke in Italy: the IN2 study.

    Science.gov (United States)

    Consoli, D; Vidale, S; Aguglia, U; Bassi, P; Cavallini, A; Galati, F; Guidetti, D; Marcello, N; Micieli, G; Pracucci, G; Rasura, M; Siniscalchi, A; Sterzi, R; Toni, D; Inzitari, D

    2015-03-01

    There is an increasing interest in new risk factors for ischaemic stroke. Acute and chronic infections could contribute to different aetiological mechanisms of atherosclerosis that lead to cerebrovascular disease. The aim of this study was to investigate the hypothesis that previous infections and Chlamydia pneumoniae in particular increase the risk of ischaemic stroke in the population. This was a prospective case-control study involving 11 Italian stroke units. Controls were age- and sex-matched with cases, represented by patients admitted to hospital for acute ischaemic stroke. For each participant classical vascular risk factors and previous inflammatory and infectious events up to 1 month before were registered. Blood samples were collected to analyse inflammatory markers and titres of antibodies against C. pneumoniae. A total of 1002 participants were included (mean age 69 years) with 749 ischaemic stroke patients. Infections occurred within 1 month previously in 12% of the entire sample with a higher prevalence in the case group (14.4% vs. 3.9%). At multivariate analysis of the seropositivity of IgA antibodies against C. pneumoniae increased the risk of stroke significantly (relative risk 2.121; 95% confidence interval 1.255-3.584) and an early previous infection (up to 7 days before the event) contributed to a rise in probability of acute cerebral ischaemia (relative risk 3.692; 95% confidence interval 1.134-6.875). Early previous infections and persistent chronic infection of C. pneumoniae could contribute to increase the risk of ischaemic stroke significantly, in the elderly especially. © 2014 EAN.

  1. Sand resources, regional geology, and coastal processes for shoreline restoration: case study of Barataria shoreline, Louisiana

    Science.gov (United States)

    Kindinger, Jack G.; Flocks, James G.; Kulp, Mark; Penland, Shea; Britsch, Louis D.

    2002-01-01

    The Louisiana barrier shoreline of Barataria Basin, which lies within the western Mississippi River delta, has undergone significant retreat during the past 100 years. The most practical restoration method to rebuild these shorelines is sand nourishment. Seismic and sonar interpretations verified with geologic samples (vibracores and borings) indicate that there are nine sand targets within the Barataria study area that meet or exceed the minimum criteria for potential resource sites. However, the near surface lithology in the basin is typically silts and clays. Locating suitable sand resources for shoreline restoration is challenging. The sand units are associated with geologic depositional systems such as ebb-tidal deltas, distributary mouth bars, and channel fill (undifferentiated fluvial or tidal inlet channels). The nine potential sand targets consist primarily of fine sand and can be delineated into three surficial and six buried features. The surficial features contain approximately 10% of the total sand resources identified. At least 90% of the sand resources need overburden sediment removed prior to use; almost 570 million yd3 (438.5 mil m3) of overburden will need to be removed if the entire resource is mined. In this study, we identified 396 to 532 mil yd3 (305.8 to 410.8 mil m3) of potential sand deposits for shoreline restoration. Previous studies using less dense survey methods greatly over-estimated sand resources available in this area. Many fluvial channels reported previously as sand-filled are mud-filled. Contrary to these previous studies, few fluvial subsystems in this region have abundant sand resources.

  2. Habitat geology studies on and near Georges Bank, off New England

    Science.gov (United States)

    Valentine, P.C.

    2001-01-01

    Marine habitat geology is the study of the distribution of geologic materials that form the seabed, the geologic processes (such as sediment movement and deposition) that affect the seabed, and the interplay of geologic factors and species behavior that gives rise to biological habitats in general and to specific habitats deemed essential to the success of a particular species (essential fish habitats, EFH's). Georges Bank was once the premier East Coast fishing ground for groundfish and scallops. The decline of groundfish species due to overfishing contributed to the increasingly restrictive management of fish stocks and a need to identify and protect EFH's.

  3. Study of uranium oxidation states in geological material.

    Science.gov (United States)

    Pidchenko, I; Salminen-Paatero, S; Rothe, J; Suksi, J

    2013-10-01

    A wet chemical method to determine uranium (U) oxidation states in geological material has been developed and tested. The problem faced in oxidation state determinations with wet chemical methods is that U redox state may change when extracted from the sample material, thereby leading to erroneous results. In order to quantify and monitor U redox behavior during the acidic extraction in the procedure, an analysis of added isotopic redox tracers, (236)U(VI) and (232)U(IV), and of variations in natural uranium isotope ratio ((234)U/(238)U) of indigenous U(IV) and U(VI) fractions was performed. Two sample materials with varying redox activity, U bearing rock and U-rich clayey lignite sediment, were used for the tests. The Fe(II)/Fe(III) redox-pair of the mineral phases was postulated as a potentially disturbing redox agent. The impact of Fe(III) on U was studied by reducing Fe(III) with ascorbic acid, which was added to the extraction solution. We observed that ascorbic acid protected most of the U from oxidation. The measured (234)U/(238)U ratio in U(IV) and U(VI) fractions in the sediment samples provided a unique tool to quantify U oxidation caused by Fe(III). Annealing (sample heating) to temperatures above 500 °C was supposed to heal ionizing radiation induced defects in the material that can disturb U redox state during extraction. Good agreement between two independent methods was obtained for DL-1a material: an average 38% of U(IV) determined by redox tracer corrected wet chemistry and 45% for XANES. Copyright © 2013 Elsevier Ltd. All rights reserved.

  4. U.S. Geological Survey Rewarding Environment Culture Study, 2002

    Science.gov (United States)

    Nash, Janis C.; Paradise-Tornow, Carol A.; Gray, Vicki K.; Griffin-Bemis, Sarah P.; Agnew, Pamela R.; Bouchet, Nicole M.

    2010-01-01

    In its 2001 review of the U.S. Geological Survey (USGS), the National Research Council (NRC, p. 126) cautioned that ?high-quality personnel are essential for developing high-quality science information? and urged the USGS to ?devote substantial efforts to recruiting and retaining excellent staff.? Recognizing the importance of the NRC recommendation, the USGS has committed time and resources to create a rewarding work environment with the goal of achieving the following valued outcomes: ? USGS science vitality ? Customer satisfaction with USGS products and services ? Employee perceptions of the USGS as a rewarding place to work ? Heightened employee morale and commitment ? The ability to recruit and retain employees with critical skills To determine whether this investment of time and resources was proving to be successful, the USGS Human Resources Office conducted a Rewarding Environment Culture Study to answer the following four questions. ? Question 1: Does a rewarding work environment lead to the valued outcomes (identified above) that the USGS is seeking? ? Question 2: Which management, supervisory, and leadership behaviors contribute most to creating a rewarding work environment and to achieving the valued outcomes that the USGS is seeking? ? Question 3: Do USGS employees perceive that the USGS is a rewarding place to work? ? Question 4: What actions can and should be taken to enhance the USGS work environment? To begin the study, a conceptual model of a rewarding USGS environment was developed to test assumptions about a rewarding work environment. The Rewarding Environment model identifies the key components that are thought to contribute to a rewarding work environment and the valued outcomes that are thought to result from having a rewarding work environment. The 2002 Organizational Assessment Survey (OAS) was used as the primary data source for the study because it provided the most readily available data. Additional survey data were included as they

  5. Engineering geology studies in the National Petroleum Reserve, Alaska

    Science.gov (United States)

    Kachadoorian, Reuben; Crory, F.E.

    1984-01-01

    Engineering geology studies were conducted in direct support of the exploration program in the National Petroleum Reserve, Alaska. The studies included laboratory and field tests and observations to address design and construction problems of airfields, roads, drill pads and foundations, and to evaluate their actual performance. Permafrost containing large amounts of near surface ground ice as wedges, masses, and intergranular ice, required that all construction activity not disturb the thermal regime of the ground surface, which could lead to thaw of permafrost and ground subsidence. Summer activity, therefore was not allowable, yet the winter climate was so harsh that winter work was slow and inefficient. To allow summer operations at well sites planned for all year activity, it was necessary to adapt existing techniques for arctic construction and to devise new ones. The design and construction of facilities at the deep exploration wells at Inigok, Tunalik, and Lisburne posed the greatest challenge. These sites, requiring a year or more to drill, could only be attempted if continuous access to drilling and logistic supplies could be assured throughout the year, including the possibility of bringing in another drill rig, in the event of a blowout. Thus all-seasons airstrips were required at these wells. Sufficient quantities of local gravel were not readily available at the Inigok and Tunalik sites to construct the airstrips with the required 6 feet or more of gravel to prevent the underlying permafrost from thawing. Therefore, insulation was used to maintain the subbase of local sands in a continuously frozen state, which in turn was overlain by 15 inches of gravel or sandy gravel. Tests at the U.S. Army Waterways Experimental Station defined the minimum thickness of gravel required above the insulation to provide the desired bearing capacity for the C-130 type aircraft without crushing the insulation. Field testing also included the evaluation of another design

  6. HIV-related neuropsychological impairment in patients with previous substance use: A preliminary study

    OpenAIRE

    García-Torres, Amalia; Vergara-Moragues, Esperanza (UNIR); Piñón-Blanco, Adolfo; Pérez-García, Miguel

    2015-01-01

    Human immunodeficiency virus (HIV) can result in cognitive disorders that significantly interfere with the daily activities of HIV patients. These disorders may be worse when there is a history of psychoactive substance use. Our objective is to assess the neuropsychological profile in a group of HIV patients with previous drug use compared to a group of HIV-negative patients with a history of drug use. The study included a total of 28 Spanish adult subjects, of which 14 were HIV-infected and ...

  7. Data from studies of previous radioactive waste disposal in Massachusetts Bay

    International Nuclear Information System (INIS)

    Curtis, W.R.; Mardis, H.M.

    1984-12-01

    This report presents the results of studies conducted in Massachusetts Bay during 1981 and 1982. Included are data from: (1) a side scan sonar survey of disposal areas in the Bay that was carried out by the National Oceanic and Atmospheric Administration (NOAA) for EPA; (2) Collections of sediment and biota by NOAA for radiochemical analysis by EPA; (3) collections of marketplace seafood samples by the Food and Drug Administration (FDA) for radioanalysis by both FDA and EPA; and (4) a radiological monitoring survey of LLW disposal areas by EPA to determine whether there should be any concern for public health resulting from previous LLW disposals in the Bay

  8. Cystic echinococcosis in Jordan: A review of causative species, previous studies, serological and radiological diagnosis.

    Science.gov (United States)

    Hijjawi, Nawal S; Al-Radaideh, Ali M; Rababah, Eman M; Al-Qaoud, Khaled M; Bani-Hani, Kamal E

    2018-03-01

    Cystic echinococcosis (CE)/hydatidosis is a zoonotic disease which occur in human and herbivore animals as a result of infection with the larval stage of the taeniid cestode Echinococcus granulosus sensu lato (s. l.). In human, CE is a serious public health concern in many parts of the world including Jordan. The present review will cover CE causative agent: E. granulosus species/genotypes; life cycle of E. granulosus parasite, all published previous studies on CE in Jordan (humans, intermediate hosts, definitive host) as well as its diagnostic methods in human. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Study on systematic integration technology of design and safety assessment for HLW geological disposal

    International Nuclear Information System (INIS)

    Ishihara, Yoshinao; Fukui, Hiroshi; Sagawa, Hiroshi; Matsunaga, Kenichi; Ito, Takaya; Kohanawa, Osamu; Kuwayama, Yuki

    2002-03-01

    The present study was carried out relating to basic design of the Geological Disposal Technology Integration System' that will be systematized as knowledge base for analysis and assessment of geological disposal by integrating organically and hierarchically analysis and evaluation method in three study field. The key conclusions are summarized as follows: (1) The examination to construct the virtual geological disposal system which contained the geological environment on the computer was executed aiming at the development of integration and the analysis systems which became working common basic to execute the design and the performance assessment of the geological disposal system. (2) Technological information (I/O information) which became the base was associated with work (evaluation) item of 'Disposal technology (design)' and 'Performance assessment' in the Second Progress Report by JNC, and the evaluation flow by which a series of work concerning the design and the safety assessment of the geological disposal system was brought together was made. (3) The subject concerning the detailed model development in the R and D activity of the geological disposal system in the future was extracted aiming at the systematization of the performance and safety assessment, and was arranged as information to take these detailed models into the 'Geological Disposal Technology Integration System'. (author)

  10. Inference of a seismic gap from geological data: Thessaly ( Central Greece as a case study

    Directory of Open Access Journals (Sweden)

    R. Caputo

    1995-06-01

    Full Text Available As a result of neotectonic, morphotectonic and seismotectonic research it is now possible to draw detailed maps of the major active faults affecting Thessaly, a large region of continental Greece. For many of these faults, where specific studies have been carried out, the degree of fault activity (i.e. the long-term slip-rate has been also assigned ranging from 0.05 to 4 mm/yr-l. In the present work, the main morphotectonic features and seismotectonic characteristics of the more important faults are recalled from previous works, while the recent tectonic activity is compared with the seismic activity of the area. The occuuence of both large (M ?x2264; 6.0 and moderate (M ?x2265; 6.0 earthquakes during the present century is concentrated in the southern sector. Earthquakes have been virtually absent in the northern part of the region during the same period. In contrast, according to geological and geomorphological criteria, the recent (Late Quaternary tectonic evolution of the region and the overall extensional rate do not seem to djffer significantly in the two sectors. Although palaeosejsmological trenches, geodetic surveying and the record of the microseismic activity may enhance our knowledge of this problem, on the basis of available geological (structural and morphological data, it is likely that the northern sector of Thessaly represents a large seismic gap. The implications on seismic hazard in one of the more populated regions of Greece are also discussed.

  11. Does the previous diagnosis of arterial hypertension affect one's daily life? Pro-Saude Study.

    Science.gov (United States)

    Goffredo Filho, Gilberto Senechal de; Lopes, Claudia de Souza; Faerstein, Eduardo

    2013-12-01

    In addition to damaging several target organs, arterial hypertension may negatively impact patients' activities of daily living. Biological and behavioral mechanisms underlying such limitations have yet to be clarified. The objectives of this study were to investigate whether having been previously told of a hypertension diagnosis is associated with the frequency and duration of temporary limitations in activities of daily living, and whether these relationships differ by gender, age, or socioeconomic position. We analyzed sectional data from 2,666 participants (56% women; 55% with high school or lower schooling) at the baseline phase (1999 - 2001) of a longitudinal investigation of university employees in Rio de Janeiro, Brazil (Pró-Saúde Study), asking participants whether they had ever been diagnosed with hypertension by a health professional, if they had been unable to perform any activities of daily living due to a health problem in the previous 2 weeks, and for how many days that had occurred. Multinomial logistic regression models were fitted for the overall study population and for age, gender, educational level, and per capita household income strata. Associations between hypertension diagnosis and temporary limitations were not observed in the overall study population and in gender, education and income strata. However, there were higher odds of temporary limitations among participants aged 55 years old or more with hypertension diagnosis (adjusted OR = 9.5; 95%CI 1.5 - 58.6), regardless of blood pressure levels and use of antihypertensive medication. Elderly people may keep an attitude of higher vigilance regarding conditions or events potentially worsening their health status.

  12. Using improved technology for widespread application of a geological carbon sequestration study

    Science.gov (United States)

    Raney, J.

    2013-12-01

    The Kansas Geological Survey is part of an ongoing collaboration between DOE-NETL, academia, and the petroleum industry to investigate the feasibility of carbon utilization and storage in Kansas. Latest findings in the 25,000 mi2 study area in southern Kansas estimate CO2 storage capacity ranges from 8.8 to 75.5 billion metric tons in a deep Lower Orodovican-age Arbuckle saline aquifer. In addition, an estimated 100 million tonnes of CO2 could be used for extracting additional oil from Kansas' fields, making transitions to carbon management economic. This partnership has a rare opportunity to synchronize abundant, yet previously disseminated knowledge into a cohesive scientific process to optimize sequestration site selection and implementation strategies. Following a thorough characterization, a small-scale CO2 injection of 70,000 tonnes will be implemented in Wellington Field in Sumner County, including a five-plot miscible CO2-EOR flood of a Mississippian reservoir followed by the underlying Arbuckle saline aquifer. Best practices and lessons learned from the field study will improve estimates on CO2 storage capacity, plume migration models, and identify potential leakage pathways to pursue safe and effective geological carbon sequestration at commercial scales. A highly accessible and multifunctional online database is being developed throughout the study that integrates all acquired geological, physical, chemical, and hydrogeologic knowledge. This public database incorporates tens of thousands of data points into easily viewable formats for user downloads. An Interactive Project Map Viewer is a key mechanism to present the scientific research, and will delineate compartment candidates and reservoirs matching reference criteria or user defined attributes. This tool uses a familiar pan and zoom interface to filter regional project data or scale down to detailed digitized information from over 3,300 carefully selected preexisting Kansas wells. A Java-based log

  13. A longitudinal study of plasma insulin and glucagon in women with previous gestational diabetes

    DEFF Research Database (Denmark)

    Damm, P; Kühl, C; Hornnes, P

    1995-01-01

    OBJECTIVE: To investigate whether plasma insulin or glucagon predicts later development of diabetes in women with gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS: The subjects studied were 91 women with diet-treated GDM and 33 healthy women. Plasma insulin and glucagon during a 50...... at follow-up (2 had insulin-dependent diabetes mellitus, 13 had non-insulin-dependent diabetes mellitus, and 12 had impaired glucose tolerance). Compared with the control subjects, women with previous GDM had relatively impaired insulin secretion (decreased insulinogenic index and delayed peak insulin...... for subsequent development of overt diabetes (logistic regression analysis). CONCLUSIONS: Women who develop GDM have a relative insulin secretion deficiency, the severity of which is predictive for later development of diabetes. Furthermore, our data indicate that their relatively reduced beta-cell function may...

  14. Case-control study for colorectal cancer genetic susceptibility in EPICOLON: previously identified variants and mucins

    International Nuclear Information System (INIS)

    Abulí, Anna; Morillas, Juan D; Rigau, Joaquim; Latorre, Mercedes; Fernández-Bañares, Fernando; Peña, Elena; Riestra, Sabino; Payá, Artemio; Jover, Rodrigo; Xicola, Rosa M; Llor, Xavier; Fernández-Rozadilla, Ceres; Carvajal-Carmona, Luis; Villanueva, Cristina M; Moreno, Victor; Piqué, Josep M; Carracedo, Angel; Castells, Antoni; Andreu, Montserrat; Ruiz-Ponte, Clara; Castellví-Bel, Sergi; Alonso-Espinaco, Virginia; Muñoz, Jenifer; Gonzalo, Victoria; Bessa, Xavier; González, Dolors; Clofent, Joan; Cubiella, Joaquin

    2011-01-01

    Colorectal cancer (CRC) is the second leading cause of cancer death in developed countries. Familial aggregation in CRC is also important outside syndromic forms and, in this case, a polygenic model with several common low-penetrance alleles contributing to CRC genetic predisposition could be hypothesized. Mucins and GALNTs (N-acetylgalactosaminyltransferase) are interesting candidates for CRC genetic susceptibility and have not been previously evaluated. We present results for ten genetic variants linked to CRC risk in previous studies (previously identified category) and 18 selected variants from the mucin gene family in a case-control association study from the Spanish EPICOLON consortium. CRC cases and matched controls were from EPICOLON, a prospective, multicenter, nationwide Spanish initiative, comprised of two independent stages. Stage 1 corresponded to 515 CRC cases and 515 controls, whereas stage 2 consisted of 901 CRC cases and 909 controls. Also, an independent cohort of 549 CRC cases and 599 controls outside EPICOLON was available for additional replication. Genotyping was performed for ten previously identified SNPs in ADH1C, APC, CCDN1, IL6, IL8, IRS1, MTHFR, PPARG, VDR and ARL11, and 18 selected variants in the mucin gene family. None of the 28 SNPs analyzed in our study was found to be associated with CRC risk. Although four SNPs were significant with a P-value < 0.05 in EPICOLON stage 1 [rs698 in ADH1C (OR = 1.63, 95% CI = 1.06-2.50, P-value = 0.02, recessive), rs1800795 in IL6 (OR = 1.62, 95% CI = 1.10-2.37, P-value = 0.01, recessive), rs3803185 in ARL11 (OR = 1.58, 95% CI = 1.17-2.15, P-value = 0.007, codominant), and rs2102302 in GALNTL2 (OR = 1.20, 95% CI = 1.00-1.44, P-value = 0.04, log-additive 0, 1, 2 alleles], only rs3803185 achieved statistical significance in EPICOLON stage 2 (OR = 1.34, 95% CI = 1.06-1.69, P-value = 0.01, recessive). In the joint analysis for both stages, results were only significant for rs3803185 (OR = 1.12, 95% CI = 1

  15. Case-control study for colorectal cancer genetic susceptibility in EPICOLON: previously identified variants and mucins

    Directory of Open Access Journals (Sweden)

    Moreno Victor

    2011-08-01

    Full Text Available Abstract Background Colorectal cancer (CRC is the second leading cause of cancer death in developed countries. Familial aggregation in CRC is also important outside syndromic forms and, in this case, a polygenic model with several common low-penetrance alleles contributing to CRC genetic predisposition could be hypothesized. Mucins and GALNTs (N-acetylgalactosaminyltransferase are interesting candidates for CRC genetic susceptibility and have not been previously evaluated. We present results for ten genetic variants linked to CRC risk in previous studies (previously identified category and 18 selected variants from the mucin gene family in a case-control association study from the Spanish EPICOLON consortium. Methods CRC cases and matched controls were from EPICOLON, a prospective, multicenter, nationwide Spanish initiative, comprised of two independent stages. Stage 1 corresponded to 515 CRC cases and 515 controls, whereas stage 2 consisted of 901 CRC cases and 909 controls. Also, an independent cohort of 549 CRC cases and 599 controls outside EPICOLON was available for additional replication. Genotyping was performed for ten previously identified SNPs in ADH1C, APC, CCDN1, IL6, IL8, IRS1, MTHFR, PPARG, VDR and ARL11, and 18 selected variants in the mucin gene family. Results None of the 28 SNPs analyzed in our study was found to be associated with CRC risk. Although four SNPs were significant with a P-value ADH1C (OR = 1.63, 95% CI = 1.06-2.50, P-value = 0.02, recessive, rs1800795 in IL6 (OR = 1.62, 95% CI = 1.10-2.37, P-value = 0.01, recessive, rs3803185 in ARL11 (OR = 1.58, 95% CI = 1.17-2.15, P-value = 0.007, codominant, and rs2102302 in GALNTL2 (OR = 1.20, 95% CI = 1.00-1.44, P-value = 0.04, log-additive 0, 1, 2 alleles], only rs3803185 achieved statistical significance in EPICOLON stage 2 (OR = 1.34, 95% CI = 1.06-1.69, P-value = 0.01, recessive. In the joint analysis for both stages, results were only significant for rs3803185 (OR = 1

  16. Planetary geology

    CERN Document Server

    Gasselt, Stephan

    2018-01-01

    This book provides an up-to-date interdisciplinary geoscience-focused overview of solid solar system bodies and their evolution, based on the comparative description of processes acting on them. Planetary research today is a strongly multidisciplinary endeavor with efforts coming from engineering and natural sciences. Key focal areas of study are the solid surfaces found in our Solar System. Some have a direct interaction with the interplanetary medium and others have dynamic atmospheres. In any of those cases, the geological records of those surfaces (and sub-surfaces) are key to understanding the Solar System as a whole: its evolution and the planetary perspective of our own planet. This book has a modular structure and is divided into 4 sections comprising 15 chapters in total. Each section builds upon the previous one but is also self-standing. The sections are:  Methods and tools Processes and Sources  Integration and Geological Syntheses Frontiers The latter covers the far-reaching broad topics of exo...

  17. 2009 U.S. Geological Survey (USGS) Lidar: Umpqua River Study Area

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Watershed Sciences, Inc. collected Light Detection and Ranging (LiDAR) data for the U.S. Geological Survey (USGS) Umpqua River study site in collaboration with the...

  18. Regional geology, tectonic, geomorphology and seismology studies to interest to nuclear power plants at Itaorna beach

    International Nuclear Information System (INIS)

    Hasui, Y.; Almeida, F.F.M. de; Mioto, J.A.; Melo, M.S. de.

    1982-01-01

    The study prepared for the nuclear power plants to be located at Itaorna comprised, the analysis and integration of Geologic, tectonic, geomorphologic and seismologic information and satisfactory results of regional stability were obtained. (L.H.L.L.) [pt

  19. Studies from the history of soil science and geology

    Science.gov (United States)

    Landa, Edward R.; Cohen, Benjamin R.

    2010-01-01

    The United Nations proclaimed the year 2008 as the official International Year of Planet Earth (IYPE), with science and outreach activities spanning 2007–2009. IYPE-sponsored outreach helped focus the attention of the general public on topics such as human health and the environment; ocean and natural resources sustainability; mitigating natural hazards and community resilience; and the effects of climate change. Within the earth science community, the IYPE was a stimulus for retrospection, and for efforts aimed at bridging divides within the community. One such effort was the first joint meeting of the Geological Society of America (GSA) and the Soil Science Society of America (SSSA), held in Houston, Texas, 5–9 October 2008.

  20. A study about the interest and previous contact of high school students with Astronomy

    Science.gov (United States)

    Carvalho, C. L.; Zanitti, M. H. R.; Felicidade, B. L.; Gomes, A. D. T.; Dias, E. W.; Coelho, F. O.

    2016-04-01

    The currently problems in Astronomy teaching in Brazilian Basic Education contrast with the space, and the popularity that astronomical themes have in various media in the country. In this work, we present the results of a study about the interest, and previous contact of high school students from a public school in the city of "São João del-Rei"/MG with topics related to Astronomy. The study and the pedagogical intervention were carried out by students of the PIBID/CAPES/UFSJ. The intervention was performed through an oral exposition with the students' participation, followed by the use of the Stellarium program. The results suggest the majority of students surveyed are interested in Astronomy, and have had some contact with the area. However, some inconsistencies in their responses were identified and examined. The implications for research and for Astronomy Education are discussed. We also make some considerations about relationship between the lack of specific knowledge and the misinformation as one possible reason for the little interest of students in various areas of Science.

  1. Biosystematic studies on Dactylis L. l. Review of the previous studies. 1.2. Cytology, genetics, experimental studies, and evolution

    Directory of Open Access Journals (Sweden)

    Marta Mizianty

    2014-01-01

    Full Text Available In this paper the author presents a review of the previous studies on Dactylis L., dealing with cytology,genetics, experimental studies and evolution. Following cytotypes of Dactylis are distributed mostly in Central Europe: 16 diploids, 7 tetraploids and also 2 hexaploids in North Africa. Some aneuploids and accessory chromosomes were also found in this genus. Data dealing with karyotypes of some taxa, and geographical distribution of cytotypes are also listed. Selected problems concerning crossing within diploids as well as tetraploids and also between diploids and teraploids were presented. Some opinions regarding the evolution in the genus Dactylis were also demonstrated. In all these hypotheses the following diploids are considered to be the oldest: D. smithii Link subsp. smithii, D. g. subsp. aschersoniana (Greabn. Thell. and D. g. subsp. himalayensis Dom.

  2. Hydro-geological studies at the PINSTECH quadrangle

    International Nuclear Information System (INIS)

    Mehmood, K.; Qureshi, A.A.; Khattak, N.; Akram, M.; Farooq, M.

    2000-05-01

    In order to save the huge amount of water bill and to overcome the shortage of water supply during summer, a resistivity survey was carried out to locate some suitable water bearing horizons within the PINSTECH Quadrangle. Eight shallow bore holes yielding limited amount of water supply were also drilled on trial basis. The work so far done indicates the existence of two water-bearing horizons in this area. a. A shallow water bearing horizon present at the contact of recent alluvium with bedrock at a depth between 7-20 meters. b. A deep water bearing horizon present erratically in the sandstone of Kamlial Formation at a depth between 85-180 meters. On the basis of resistivity measurements, thirteen sites have been earmarked which may contain water bearing zones in the deep horizon. Out of these, nine sites have been classified as the favorable and four as semi-favorable sites. A geological survey of the area was also carried out. The Kamlial sandstone, indicated by the resistivity survey to contain water bearing zones, is less porous with low permeability. Therefore it is not a favorable lithology to contain an aquifer to produce a good water discharge. However, the hole/s penetrating through a faulted/fractured zone being charged through a stream in the vicinity may yield water. (author)

  3. Geotourism, Medical Geology and local development: Cape Verde case study

    Science.gov (United States)

    Rocha, F.; Ferreira da Silva, E.

    2014-11-01

    Geotourism and Geoparks in particular are real opportunities to rural developments promoting the rate decline of unemployment and emigration through engaging the local communities in geopark activities and tourism marketing in the form of adventure tourism, ecotourism, rural tourism and health geotourism. Geotourism is closely linked with Medical Geology. The intake of minerals and chemical elements for food, water, soil (through geophagy) or dust can be accomplished by ingestion, inhalation or dermal absorption. Pelotherapy or “Mudtherapy” is the use of mud/clay for therapeutic applications, internal or external. Cape Verde archipelago is located in Atlantic ocean, 400 km westwards of Senegal coast. Geotourism is being developed, mainly focused on the development of a geopark in Fogo island huge caldera, but also trying to take advantage of their potentialities for Geomedecine. A cooperative program established between Cape Verde University (UCV) and Aveiro University (UA, Portugal) is under way, aiming, on a first stage, to identify Geotouristic potentialities and, on a second stage, to develop products. Geotourism is being developed, mainly focused on the development of a geopark in Fogo isl. huge caldera, but also trying to take advantage of their potentialities for Geomedecine.

  4. Study on geological environment in the Tono area. An approach to surface-based investigation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-12-01

    Mizunami Underground Research (MIU) Project has aimed at preparation of basis of investigation, analysis and evaluation of geology of deep underground and basis of engineering technologies of ultra deep underground. This report stated an approach and information of surface-based investigation for ground water flow system and MIU Project by the following contents, 1) objects and preconditions, 2) information of geological environment for analysis of material transition and design of borehole, 3) modeling, 4) tests and investigations and 5) concept of investigation. The reference data consists of results of studies such as the geological construction model, topography, geologic map, structural map, linear structure and estimated fault, permeability, underground stream characteristics, the quality of underground water and rock mechanics. (S.Y.)

  5. The part played by applied geology in nuclear power plant site studies

    International Nuclear Information System (INIS)

    Giafferi, J.L.

    1994-01-01

    Site-related geological problems are one of the constraints affecting the environment of nuclear power plants. The natural features (soil and subsoil) at the nuclear power plant site affect numerous factors in the design, construction and operation of the civil engineering structures. The site geological criteria are not solely restricted to the soil as a static support for the structures. Earth tremors in France are of moderate intensity but the likelihood of their occurrence must nevertheless be taken into account for each site. Studies must concern the geological and seismic features of the region as well as the soil and subsoil configurations and composition in the immediate vicinity of the site in order to determine the physical characteristics of the earthquakes so that the safety of the plant can be guaranteed; in many cases, water tables have also to be taken into consideration. Geologic survey techniques are discussed. 13 figs., 7 refs

  6. The biomechanics of running in athletes with previous hamstring injury: A case-control study.

    Science.gov (United States)

    Daly, C; Persson, U McCarthy; Twycross-Lewis, R; Woledge, R C; Morrissey, D

    2016-04-01

    Hamstring injury is prevalent with persistently high reinjury rates. We aim to inform hamstring rehabilitation by exploring the electromyographic and kinematic characteristics of running in athletes with previous hamstring injury. Nine elite male Gaelic games athletes who had returned to sport after hamstring injury and eight closely matched controls sprinted while lower limb kinematics and muscle activity of the previously injured biceps femoris, bilateral gluteus maximus, lumbar erector spinae, rectus femoris, and external oblique were recorded. Intergroup comparisons of muscle activation ratios and kinematics were performed. Previously injured athletes demonstrated significantly reduced biceps femoris muscle activation ratios with respect to ipsilateral gluteus maximus (maximum difference -12.5%, P = 0.03), ipsilateral erector spinae (maximum difference -12.5%, P = 0.01), ipsilateral external oblique (maximum difference -23%, P = 0.01), and contralateral rectus femoris (maximum difference -22%, P = 0.02) in the late swing phase. We also detected sagittal asymmetry in hip flexion (maximum 8°, P = 0.01), pelvic tilt (maximum 4°, P = 0.02), and medial rotation of the knee (maximum 6°, P = 0.03) effectively putting the hamstrings in a lengthened position just before heel strike. Previous hamstring injury is associated with altered biceps femoris associated muscle activity and potentially injurious kinematics. These deficits should be considered and addressed during rehabilitation. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  7. Generalizing geological maps with the GeoScaler software: The case study approach

    Science.gov (United States)

    Smirnoff, Alex; Huot-Vézina, Gabriel; Paradis, Serge J.; Boivin, Ruth

    2012-03-01

    Map generalization is rapidly becoming an important task in surficial and bedrock geology as broader regional and cross-boundary compilations are made from maps originally describing more specific areas. However, the entire process is still not defined in sufficient detail and relatively few automated tools are available. Moreover, the existing tools are primarily designed for generalization of topographic maps and do not address the needs specific to geology. Here we present two case studies describing our approach to the generalization of surficial and bedrock geology maps, respectively. To accomplish the task, we employed the GeoScaler software developed at the Laboratoire de cartographie numérique et de photogrammétrie (LCNP) of the Quebec division of the Geological Survey of Canada (Version 2009). The software is free over the Internet but requires an ArcGIS (ArcInfo) license. Four surficial geology maps at 1:250,000 scale were produced from 14 maps scaled at 1:100,000, while a single compilation of six bedrock maps was generalized from 1:125,000 to 1:500,000 scale. We describe the general considerations required to approach any generalization exercise, applied software, objectives, input data, major generalization steps, and the final results. All generalized maps were favorably evaluated by experts in geological mapping and the surficial maps have been published.

  8. Rancidity inhibition study in frozen whole mackerel (scomber scombrus by a previous plant extract treatment.

    Directory of Open Access Journals (Sweden)

    Aubourg, Santiago P.

    2005-09-01

    Full Text Available The effect of flaxseeds (Linum usitatissimum on rancidity development in frozen whole mackerel (Scomber scombrus was studied. For it, fresh mackerel were dipped in flaxseeds aqueous extract during 60 min, frozen at –80 ºC during 24 hours and kept frozen (–20 ºC up to 12 months. Sampling was carried out on the initial material and at months 1, 3, 5, 7, 9 and 12 of frozen storage at –20 ºC. A parallel experiment with non treated fish was carried out in the same conditions. Rancidity development was measured by several biochemical indices (free fatty acids, peroxides, conjugated dienes and trienes, secondary oxidation products and lipoxygenase activity and complemented by the sensory analysis (skin, flesh odour, consistency and flesh appearance. As a result of the previous antioxidant treatment, peroxides showed to breakdown faster (pSe ha estudiado el efecto del lino (Linum usitatissimum en el desarrollo de rancidez en caballa entera congelada (Scomber scombrus. Para ello, caballas frescas fueron sumergidas en extractos acuosos de semillas de lino durante 60 min, congeladas a -80 ºC durante 24 h y mantenidas congeladas ( -20 ºC durante 12 meses. Se tomaron muestras del material inicial y tras 1, 3, 5, 7, 9 y 12 meses de congelación a -20 ºC . Un experimento paralelo con pescado no tratado fue llevado acabo en las mismas condiciones. El desarrollo de la rancidez fue medido por varios índices bioquímicos (ácidos grasos libres, peróxidos, dienos y trienos conjugados, productos secundarios de oxidación y actividad lipoxigenasa y completado con análisis sensorial (piel, olor de la carne, consistencia y apariencia de la carne. Como resultado del tratamiento antioxidante, los peróxidos se degradaron más rápidos (p < 0.05 después del mes 7, y por tanto, contenidos mayores (p < 0.05 de dienos y trienos conjugados pudieron ser detectados en el pescado tratado. El tratamiento antioxidante también condujo a un

  9. Study of geological details towards feasibility of uranium project: Indian case studies

    International Nuclear Information System (INIS)

    Sarangi, A.

    2014-01-01

    Appropriate technical evaluation of geological details at early stage of exploration is the key to minimising the lead-time between discovery and production. This has a major influence on economic viability of the deposits. Indian uranium deposits are of medium-tonnage and low-grade occurring in dissimilar geological provinces. Detailed studies of geological characteristics of these deposits are very vital to the proper selection of technology and subsequent successful operation. The method of mining (underground/open pit/in-situ recovery) is influenced by the ore body depth, size, grade, configuration, hostrock and adjoining strata characteristics, hydrological condition etc. The ore processing technology is also subjective to mineralogical characteristics of the ore. In order to draw the flowsheet, determine process parameters and selection of reagents, a comprehensive study on identification of minerals and their probable metallurgical characteristics, general physical relationship between various minerals, mineral liberation size etc is of great significance. The technology for disposal of tailings is also influenced by geological/geo-hydrological characteristics. The key to successful operation of Indian uranium deposits lies in outlining a pre-development strategy as the exploration advances to different stages. This phase called ''exploratory mining'' - which starts with detailed exploration and ends with approval of the project is very critical for early commissioning of the project. The activities during this period include collection of representative drill core samples during exploration, laboratory studies, geo-technical studies and determination of geomechanical properties of ore and waste rock etc. Later, the ore lenses are accessed through limited entry(ies). Developments along the ore body helps in better understanding of the configuration of the lenses. Studies for strata control in case of underground mining are carried out

  10. Effect of Previous Irradiation on Vascular Thrombosis of Microsurgical Anastomosis: A Preclinical Study in Rats

    Science.gov (United States)

    Gallardo-Calero, Irene; López-Fernández, Alba; Romagosa, Cleofe; Vergés, Ramona; Aguirre-Canyadell, Marius; Soldado, Francisco; Velez, Roberto

    2016-01-01

    Background: The objective of the present investigation was to compare the effect of neoadjuvant irradiation on the microvascular anastomosis in cervical bundle using an experimental model in rats. Methods: One hundred forty male Sprague–Dawley rats were allocated into 4 groups: group I, control, arterial microanastomosis; group II, control, venous microanastomosis; group III, arterial microanastomosis with previous irradiation (20 Gy); and group IV, venous microanastomosis with previous irradiation (20 Gy). Clinical parameters, technical values of anastomosis, patency, and histopathological parameters were evaluated. Results: Irradiated groups (III and IV) and vein anastomosis groups (II and IV) showed significantly increased technical difficulties. Group IV showed significantly reduced patency rates (7/35) when compared with the control group (0/35). Radiotherapy significantly decreased the patency rates of the vein (7/35) when compared with the artery (1/35). Groups III and IV showed significantly reduced number of endothelial cells and also showed the presence of intimal thickening and adventitial fibrosis as compared with the control group. Conclusion: Neoadjuvant radiotherapy reduces the viability of the venous anastomosis in a preclinical rat model with a significant increase in the incidence of vein thrombosis. PMID:27975009

  11. STUDI PENDAHULUAN GEOLOGI GUA LAWA DI PURBALINGGA, JAWA TENGAH

    Directory of Open Access Journals (Sweden)

    Asmoro Widagdo

    2007-08-01

    Full Text Available Lawa Cave in Purbalingga Regency is a special type of cave as it formed not at calcareous rocks like at the usual cave. It is formed by lava flow processes. So, it is made of an igneous rock and it has an andesit basaltic rock type. Lawa Cave formed due to lava flow of the volcanic eruption of the Old Slamet Volcano. The rocks composition of Lawa Cave consists of primary minerals that are plagioclase and volcanic glass and some secondary mineral like calcite and ferri oxide which is fill the previous gas pores. Generally, rock fractures in Lawa Cave is formed as primary joint when the lava flow was cooling down, tectonic joints is found very limited. Lawa Cave’s direction is controlled by the flow direction of the melting lava. It’s direction indicate the paleomorphology of the volcano.

  12. Geologic and radiometric study in the Picacho, Arizpe's Municipality, Sorora (Mexico) area

    International Nuclear Information System (INIS)

    Garcia y Barragan, J.C.

    1975-01-01

    This research work was aimed chiefly at studying the geology and radiometry of the El Picacho area in order to establish its uranium mineralization potential. Another purpose was to ascertain the factors favouring deposition of radioactive material in areas bordering on the Sierra del Manzanal, where the work was carried out. Detailed geological-radiometric surveys were made, both inside the El Picacho mine and at the surface. The geological surveys were carried out by means of compass bearings and stadia, while scintillometers and spectrometers were used for the radiometric studies. The work was supported by a general geological exploration of the central part of the Serra del Manzanal. To ascertain the radiometric anomalies, the distribution of the population of values was determined by statistical methods, the frequency, cumulative frequency and frequency percentage being evaluated for that purpose. The geological survey at the El Picacho mine revealed a group of fractures enclosing the following minerals: torbernite, iriginite and autunite. These fractures are no thicker than 5 cm and tend to wedge out after 3 meters. Primary uraniferous ore is likely to be found in this zone, so surveys based on (a) radon gas emanometry and (b) sediment geochemistry in the Siera del Manzanal are recommended. The basic data relating to this area could be supplemented by mineragraphic and X-ray studies, which would provide a fuller picture of the class of mineralogical species and of the paragenesis of radioactive material presnent in the zone. (author)

  13. Geological Fieldwork: A Study Carried out with Portuguese Secondary School Students

    Science.gov (United States)

    Esteves, Helena; Ferreira, Paulo; Vasconcelos, Clara; Fernandes, Isabel

    2013-01-01

    Recognizing the relevance that fieldwork and field trips have in the teaching of geosciences and related learning processes, this study presents two geological fieldwork studies that were established with Portuguese secondary school students. Both studies were focused on geoscience content knowledge, and attempted to increase environmental…

  14. Study on the background information for the R and D of geological disposal

    International Nuclear Information System (INIS)

    Matsui, Kazuaki; Hirusawa, Shigenobu; Komoto, Harumi

    2001-02-01

    It is quite important for Japan Nuclear Cycle Development Institute (JNC) to analyze the R and D items after 'H12 report' and also provide their results of R and D activities to general public effectively. Recognizing the importance of the social consensus to the geological disposal, relating background informations were to be picked up. In this fiscal year, following two main topics were selected and studied. 1. Research and analysis on the options for the geological disposal concept. The major nuclear power-generating countries have almost all chosen deep geological disposal as preferred method for HLW disposal. Since 1990's, to make the geological disposal flexible, the alternative concepts for the disposal of HLW have been discussed promoting the social acceptance. In this context, recent optional discussions and international evaluations on the following topics were studied and summarized. (1) Reversibility of waste disposal/Retrievability of waste/Waste monitoring, (2) Long-term storage concept and its effectiveness, (3) Present position and role of international disposal. 2. Research and analysis on some educational materials collected from foreign countries. Although geological disposals is scheduled to start still in future, it is quite important to study the procedures to attract younger generation and get their proper perceptions on the nuclear energy and waste problems. As the supporting analysis to implement strategically the public relational activities for JNC's geological disposal R and D, particular attention was focused on the educational materials obtained in the last year's survey. Representative educational materials were selected and following items were studied and summarized. (1) Basic approach, positioning and characteristics of the educational materials, (2) Detailed analysis of the representatively selected educational materials, (3) Comparison of the analyzed characteristics and study on its feedback to Japanese materials. (author)

  15. Application of Remote Sensing in Geological Mapping, Case Study al Maghrabah Area - Hajjah Region, Yemen

    Science.gov (United States)

    Al-Nahmi, F.; Saddiqi, O.; Hilali, A.; Rhinane, H.; Baidder, L.; El arabi, H.; Khanbari, K.

    2017-11-01

    Remote sensing technology plays an important role today in the geological survey, mapping, analysis and interpretation, which provides a unique opportunity to investigate the geological characteristics of the remote areas of the earth's surface without the need to gain access to an area on the ground. The aim of this study is achievement a geological map of the study area. The data utilizes is Sentinel-2 imagery, the processes used in this study, the OIF Optimum Index Factor is a statistic value that can be used to select the optimum combination of three bands in a satellite image. It's based on the total variance within bands and correlation coefficient between bands, ICA Independent component analysis (3, 4, 6) is a statistical and computational technique for revealing hidden factors that underlie sets of random variables, measurements, or signals, MNF Minimum Noise Fraction (1, 2, 3) is used to determine the inherent dimensionality of image data to segregate noise in the data and to reduce the computational requirements for subsequent processing, Optimum Index Factor is a good method for choosing the best band for lithological mapping. ICA, MNF, also a practical way to extract the structural geology maps. The results in this paper indicate that, the studied area can be divided into four main geological units: Basement rocks (Meta volcanic, Meta sediments), Sedimentary rocks, Intrusive rocks, volcanic rocks. The method used in this study offers great potential for lithological mapping, by using Sentinel-2 imagery, the results were compared with existing geologic maps and were superior and could be used to update the existing maps.

  16. Late preterm birth and previous cesarean section: a population-based cohort study.

    Science.gov (United States)

    Yasseen Iii, Abdool S; Bassil, Kate; Sprague, Ann; Urquia, Marcelo; Maguire, Jonathon L

    2018-02-21

    Late preterm birth (LPB) is increasingly common and associated with higher morbidity and mortality than term birth. Yet, little is known about the influence of previous cesarean section (PCS) and the occurrence of LPB in subsequent pregnancies. We aim to evaluate this association along with the potential mediation by cesarean sections in the current pregnancy. We use population-based birth registry data (2005-2012) to establish a cohort of live born singleton infants born between 34 and 41 gestational weeks to multiparous mothers. PCS was the primary exposure, LPB (34-36 weeks) was the primary outcome, and an unplanned or emergency cesarean section in the current pregnancy was the potential mediator. Associations were quantified using propensity weighted multivariable Poisson regression, and mediating associations were explored using the Baron-Kenny approach. The cohort included 481,531 births, 21,893 (4.5%) were LPB, and 119,983 (24.9%) were predated by at least one PCS. Among mothers with at least one PCS, 6307 (5.26%) were LPB. There was increased risk of LPB among women with at least one PCS (adjusted Relative Risk (aRR): 1.20 (95%CI [1.16, 1.23]). Unplanned or emergency cesarean section in the current pregnancy was identified as a strong mediator to this relationship (mediation ratio = 97%). PCS was associated with higher risk of LPB in subsequent pregnancies. This may be due to an increased risk of subsequent unplanned or emergency preterm cesarean sections. Efforts to minimize index cesarean sections may reduce the risk of LPB in subsequent pregnancies.

  17. Study on advanced systematic function of the JNC geological disposal technical information integration system. Research document

    International Nuclear Information System (INIS)

    Ishihara, Yoshinao; Fukui, Hiroshi; Sagawa, Hiroshi; Matsunaga, Kenichi; Ito Takaya

    2004-02-01

    In this study, while attaining systematization about the technical know-how mutually utilized between geology environmental field, disposal technology (design) field and safety assessment field, the share function of general information in which the formation of an information share and the use promotion between the technical information management databases built for every field were aimed at as an advancement of the function of JNC Geological Disposal Technical Information Integration System considered, and the system function for realizing considered in integration of technical information. (1) Since the concrete information about geology environment which is gradually updated with progress of stratum disposal research, or increases in reflected suitable for research of design and safety assessment. After arranging the form suitable for systematizing technical information, while arranging the technical information in both the fields of design and safety assessment with the form of two classes based on tasks/works, it systematized planning adjustment about delivery of technical information with geology environmental field. (2) In order to aim at integration of 3-fields technical information of geological disposal, based on the examination result of systematization of technical information, the function of mutual use of the information managed in two or more databases was considered. Moreover, while considering system functions, such as management of the use history of technical information, connection of information use, and a notice of common information, the system operation windows in consideration of the ease of operation was examined. (author)

  18. Study of delayed behaviour of clays in deep geologic formations

    International Nuclear Information System (INIS)

    Rousset, G.; Bazargan, B.; Ouvry, J.F.; Bouilleau, M.

    1993-01-01

    This study is a cost-sharing contract with the European Atomic Energy Community within the framework of Research and Development Program on Management, Storage and Radioactive Waste Disposal. The aim of the work presented in this report is to study the time-dependent behaviour of deep clays in Laboratory or in situ, by means of tests of similar geometry, in order to get easy comparisons and to study scale effect. The cylindrical geometry has been chosen as it resembles in situ works (tunnels, galleries) more closely. The first part of the study concerns a new test on hollow-cylinder. The experimental system, set up specially for this study, has allowed to conduct experiments in which 3 loading parameters may be controlled independently. Different types of experiments can therefore be conducted to study various aspects of mechanical behavior of rocks. A comprehensive experimental program was conducted in the particular case of Boom clay. In the second part of the report devoted to in situ creep or relaxation dilatometer tests, by using new techniques or loading paths, it was shown that time-dependent convergence of boreholes can reach significant values, and is dependent on the direction of the borehole. The anisotropy of the initial state of stress was also put in evidence. The proposed constitutive model (part III) appears to be very suitable to explain the behavior of the Boom clay, in view of the experimental results. In particular, the scale effect is low for Boom clay. 15 refs., 58 figs., 10 tabs

  19. Geologic and geochemical studies of the New Albany Shale Group (Devonian-Mississippian) in Illinois. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Bergstrom, R.E.; Shimp, N.F.

    1980-06-30

    The Illinois State Geological Survey is conducting geological and geochemical investigations to evaluate the potential of New Albany Group shales as a source of hydrocarbons, particularly natural gas. Geological studies include stratigraphy and structure, mineralogic and petrographic characterization; analyses of physical properties; and development of a computer-based resources evaluation system. Geochemical studies include organic carbon content and trace elements; hydrocarbon content and composition; and adsorption/desorption studies of gas through shales. Separate abstracts have been prepared for each task reported.

  20. The study of the national context in support of planning geological disposal in Romania - 15232

    International Nuclear Information System (INIS)

    Andrei, V.; Prisecary, I.

    2015-01-01

    In this paper a risk management process was studied to assess the Romanian national context concerning the setting of a geological disposal of radioactive waste. A PESTEL analysis involving political, economical, social, technical, environmental and legal issues, has been performed to identify factors that could endanger the project. The analysis of a pessimistic scenario indicates the national context could delay the schedule of the siting and site licensing process by 17.5 years. The estimation of a maximum time of 38 years for this process was considered realistic since this value was met in the countries which were confronted with suspensions/reconsiderations of the siting process of a geological disposal facility

  1. What Motivates Introductory Geology Students to Study for an Exam?

    Science.gov (United States)

    Lukes, Laura A.; McConnell, David A.

    2014-01-01

    There is a need to understand why some students succeed and persist in STEM fields and others do not. While numerous studies have focused on the positive results of using empirically validated teaching methods in introductory science, technology, engineering, and math (STEM) courses, little data has been collected about the student experience in…

  2. Radon diffusion coefficients for soils. Previous studies and their application to uranium-bearing wastes

    International Nuclear Information System (INIS)

    Sasaki, Tomozo; Gunji, Yasuyoshi; Iida, Takao

    2008-01-01

    Radon diffusion in soils has been studied over the years by many researchers. The application of such studies to the evaluation of radiation exposure caused by radon from uranium-bearing wastes disposed in a shallow land site is very important. The present paper surveyed closely relevant studies and elucidated the inherent nature of radon diffusion in terms of the definition of radon diffusion coefficients. Then, basic features of measurement methods for determining radon diffusion coefficients in soils were explained. Furthermore, theoretical aspects of radon diffusion in soils were discussed in terms of microscopic radon diffusion in soils and large-scale radon diffusion through cover soil defects for uranium mill tailings. Finally, in order to apply the radon diffusion studies to uranium-bearing waste disposal in shallow land sites, new challenges were presented: elucidation of radon diffusion in uranium-bearing wastes and cover-soil cracks, and demonstration of the validity of applying only radon diffusion in the evaluation of radiation exposure caused by radon, which would come through Japanese cover soils for uranium-bearing waste disposal. (author)

  3. A time marker instrument for kinematics movement studies: a development of previous versions

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo Laburú

    2009-03-01

    Full Text Available This article presents a time marker to study movements in kinematics. It contributes to elaborate a version of time marker which low cost and more efficient in comparison with the marker presented in another work as well as the earlier commercial version.

  4. Introduction to thematic collection "Historical and geological studies of earthquakes"

    Science.gov (United States)

    Satake, Kenji; Wang, Jian; Hammerl, Christa; Malik, Javed N.

    2017-12-01

    This thematic collection contains eight papers mostly presented at the 2016 AOGS meeting in Beijing. Four papers describe historical earthquake studies in Europe, Japan, and China; one paper uses modern instrumental data to examine the effect of giant earthquakes on the seismicity rate; and three papers describe paleoseismological studies using tsunami deposit in Japan, marine terraces in Philippines, and active faults in Himalayas. Hammerl (Geosci Lett 4:7, 2017) introduced historical seismological studies in Austria, starting from methodology which is state of the art in most European countries, followed by a case study for an earthquake of July 17, 1670 in Tyrol. Albini and Rovida (Geosci Lett 3:30, 2016) examined 114 historical records for the earthquake on April 6, 1667 on the east coast of the Adriatic Sea, compiled 37 Macroseismic Data Points, and estimated the epicenter and the size of the earthquake. Matsu'ura (Geosci Lett 4:3, 2017) summarized historical earthquake studies in Japan which resulted in about 8700 Intensity Data Points, assigned epicenters for 214 earthquakes between AD 599 and 1872, and estimated focal depth and magnitudes for 134 events. Wang et al. (Geosci Lett 4:4, 2017) introduced historical seismology in China, where historical earthquake archives include about 15,000 sources, and parametric catalogs include about 1000 historical earthquakes between 2300 BC and AD 1911. Ishibe et al. (Geosci Lett 4:5, 2017) tested the Coulomb stress triggering hypothesis for three giant (M 9) earthquakes that occurred in recent years, and found that at least the 2004 Sumatra-Andaman and 2011 Tohoku earthquakes caused the seismicity rate change. Ishimura (2017) re-estimated the ages of 11 tsunami deposits in the last 4000 years along the Sanriku coast of northern Japan and found that the average recurrence interval of those tsunamis as 350-390 years. Ramos et al. (2017) studied 1000-year-old marine terraces on the west coast of Luzon Island, Philippines

  5. Study on the migration of radionuclide through geological media

    International Nuclear Information System (INIS)

    Park, Hun Hwee; Han, Kyung Won; Han, Pil Soo; Cho, Won Jin; Lee, Jae Owan; Park, Chung Kyun; Choi, Heui Joo; Lee, Youn Myoung; Yang, Ho Yeon

    1987-05-01

    In Korea, Two disposal alternatives such as shallow land burial and rock cavern disposal of low- and intermediate- level waste are most applaudable options currently receiving attention. For each disposal method, Safety assessment is necessary to estimate the performance of a disposal system and to predict probable radiological consequences. In the present study, rock cavern disposal method is proposed as a most favorable alternative in view of Korean situation

  6. Loading technique for dynamic response studies of geological materials

    International Nuclear Information System (INIS)

    Butler, R.I.; Forrestal, M.J.

    1979-04-01

    A loading technique to study the dynamic response of tuff was explored. Loading is provided by electrically exploding etched copper mesh patterns with current from a capacitor discharge. Pressure pulses with peak pressures up to 1.25 kbar and 0.10 to 0.20 ms durations were measured with a pressure bar. The upper value of peak pressure was limited by the strength of the experimental apparatus, and higher pressure generation is possible with a redesign of test hardware. 6 figures, 2 tables

  7. Geological Study and Regional Development of Mamberamo Raya Disctrict of Papua Province, Indonesia

    Science.gov (United States)

    Tonggiroh, Adi; Asri Jaya, HS; Ria Irfan, Ulva

    2018-02-01

    The goverment of Mamberamo Raya district was established through Act No. 19 of 2007 dated 15 March 2007 as part of the administrative area of Papua Province. The administrative age of this district is relatively young requires hard work of all components in facing development challenges so that necessary strategic steps of vision and mission of regional development to achieve ideal conditions of spatial which as direction of the desired embodiment in the future. Regional development covers all technical aspects including the geological aspect that the area is located on the morphology of the mountains and Mamberamo watershed. Strategic steps require policy as an action to achieve the goal with the elaboration of operational steps to realize the welfare of peoples equally and sustainably according to the potential physiogeography of Mamberamo watershed. The geological aspect as the consideration of technical that this region belongs to the regional tectonic which is divided into the difference of fault in the north there is Yapen fault and in the south is Mamberamo-Gauttier Fault and also a consideration on the stratigraphic structure of various rock types including the dominance of sedimentary rocks. This study examines geological aspects as an element of earth science in spatial planning in Mamberamo district, especially Kasonaweja and Burmeso. The analysis is presented based on field data, in the form of geographical map data of geological structure, geological map, and earthquake data described by cluster pattern indicating regional motion relationship and rock characteristics that make up Mamberamo watershed. It finds land characteristics controlled by geological structures, rock arrangements and landforms in response to landslide, flood and seismic changes.

  8. Segmental hair analysis after a single dose of zolpidem: comparison with a previous study.

    Science.gov (United States)

    Cui, Xiaopei; Xiang, Ping; Zhang, Jingshuo; Shi, Yan; Shen, Baohua; Shen, Min

    2013-01-01

    Hair is a useful aid and sometimes even the only matrix in the analytical strategy in drug-facilitated crime (DFC) investigations. In this novel study, segmental hair analysis was performed after a single 10 mg dose of zolpidem was given to 20 Chinese volunteers. Hair was collected 1 month after administration and was analyzed using ultra-high-pressure liquid chromatography/electrospray ionization tandem mass spectrometry. Zolpidem concentrations were found to be in the range of 135.0-554.6 pg/mg in the proximal 0-2 cm segments. These results were markedly different from those reported by Villain et al., who used volunteers administered equal doses of zolpidem. The analytical method used, as well as the volunteers' hair color, inter-individual variations such as metabolic capacity, hair growth rate, drug incorporation rates, physical state of the hair, age, gender, body weight, etc. and diffusion from sweat or other secretions are all factors that should be considered when interpreting the DFC results.

  9. Life cycle impact assessment of ammonia production in Algeria: A comparison with previous studies

    International Nuclear Information System (INIS)

    Makhlouf, Ali; Serradj, Tayeb; Cheniti, Hamza

    2015-01-01

    In this paper, a Life Cycle Analysis (LCA) from “cradle to gate” of one anhydrous ton of ammonia with a purity of 99% was achieved. Particularly, the energy and environmental performance of the product (ammonia) were evaluated. The eco-profile of the product and the share of each stage of the Life Cycle on the whole environmental impacts have been evaluated. The flows of material and energy for each phase of the life cycle were counted and the associated environmental problems were identified. Evaluation of the impact was achieved using GEMIS 4.7 software. The primary data collection was executed at the production installations located in Algeria (Annaba locality). The analysis was conducted according to the LCA standards ISO 14040 series. The results show that Cumulative Energy Requirement (CER) is of 51.945 × 10 3 MJ/t of ammonia, which is higher than the global average. Global Warming Potential (GWP) is of 1.44 t CO 2 eq/t of ammonia; this value is lower than the world average. Tropospheric ozone precursor and Acidification are also studied in this article, their values are: 549.3 × 10 −6 t NMVOC eq and 259.3 × 10 −6 t SO 2 eq respectively

  10. Destination: Geology?

    Science.gov (United States)

    Price, Louise

    2016-04-01

    "While we teach, we learn" (Roman philosopher Seneca) One of the most beneficial ways to remember a theory or concept is to explain it to someone else. The offer of fieldwork and visits to exciting destinations is arguably the easiest way to spark a students' interest in any subject. Geology at A-Level (age 16-18) in the United Kingdom incorporates significant elements of field studies into the curriculum with many students choosing the subject on this basis and it being a key factor in consolidating student knowledge and understanding. Geology maintains a healthy annual enrollment with interest in the subject increasing in recent years. However, it is important for educators not to loose sight of the importance of recruitment and retention of students. Recent flexibility in the subject content of the UK curriculum in secondary schools has provided an opportunity to teach the basic principles of the subject to our younger students and fieldwork provides a valuable opportunity to engage with these students in the promotion of the subject. Promotion of the subject is typically devolved to senior students at Hessle High School and Sixth Form College, drawing on their personal experiences to engage younger students. Prospective students are excited to learn from a guest speaker, so why not use our most senior students to engage and promote the subject rather than their normal subject teacher? A-Level geology students embarking on fieldwork abroad, understand their additional responsibility to promote the subject and share their understanding of the field visit. They will typically produce a series of lessons and activities for younger students using their newly acquired knowledge. Senior students also present to whole year groups in seminars, sharing knowledge of the location's geology and raising awareness of the exciting destinations offered by geology. Geology fieldwork is always planned, organised and led by the member of staff to keep costs low, with recent visits

  11. Geological Hazards analysis in Urban Tunneling by EPB Machine (Case study: Tehran subway line 7 tunnel

    Directory of Open Access Journals (Sweden)

    Hassan Bakhshandeh Amnieh

    2016-06-01

    Full Text Available Technological progress in tunneling has led to modern and efficient tunneling methods in vast underground spaces even under inappropriate geological conditions. Identification and access to appropriate and sufficient geological hazard data are key elements to successful construction of underground structures. Choice of the method, excavation machine, and prediction of suitable solutions to overcome undesirable conditions depend on geological studies and hazard analysis. Identifying and investigating the ground hazards in excavating urban tunnels by an EPB machine could augment the strategy for improving soil conditions during excavation operations. In this paper, challenges such as geological hazards, abrasion of the machine cutting tools, clogging around these tools and inside the chamber, diverse work front, severe water level fluctuations, existence of water, and fine-grained particles in the route were recognized in a study of Tehran subway line 7, for which solutions such as low speed boring, regular cutter head checks, application of soil improving agents, and appropriate grouting were presented and discussed. Due to the presence of fine particles in the route, foam employment was suggested as the optimum strategy where no filler is needed.

  12. Effect of Acupressure, Acupuncture and Moxibustion in Women With Pregnancy-Related Anxiety and Previous Depression: A Preliminary Study

    OpenAIRE

    Suzuki, Shunji; Tobe, Chiharu

    2017-01-01

    Background In this preliminary study, we examined the effect of acupressure, acupuncture and moxibustion (oriental treatments) to prevent of the relapse/deterioration of perinatal depression in women with pregnancy-related anxiety and previous depression. Methods and results Between 2014 and 2016, there were 48 women with pregnancy-related anxiety and previous depression who had delivery at ? 22 weeks? gestation in our institute. Of these, oriental treatments were performed in eight and two w...

  13. Combined Use of Remote Sensing Data, Mineralogical Analyses, Microstructure Studies and Geographic Information System for Geological Mapping of Antiparos Island (Greece

    Directory of Open Access Journals (Sweden)

    Konstantinos G. Nikolakopoulos

    2018-03-01

    Full Text Available This study presents the combined use of field mapping, remote sensing data analysis, mineralogy, spectroscopy and GIS techniques for the geological mapping of Antiparos Island. Antiparos is part of the Cyclades Blueschist Belt located in central Aegean, where gneisses, schists and Pliocene volcanic rocks occurred. During the extended field work, a number of volcanic rock samples were collected from the southern part of Antiparos. The sampling strategy was to collect samples from the primary as well as the altered rocks in specific areas in which they were previously located from the remote sensing data processing. In this study, high resolution satellite images have been carried out in order to detect, allocate and separate the different geological formations. Furthermore, the existing geological map was georeferenced and all the tectonic lines and boundaries were digitized. All these features were implemented in a Mobile Mapper CE GPS using Arcpad GIS and checked in situ. The collected samples were analyzed in the laboratory using various techniques including XRD, Petrographic Microscopy and SEM. The qualitative mineralogical analyses were conducted by using XRD. The study was supplemented by the petrographic observations providing a detailed characterization of rock textures. In addition, SEM study and SEM-EDS analyses of the samples were emphasized on the genetic relations of the minerals. The laboratory results revealed that specific corrections should be made in the previous geological map of Antiparos concerning the volcanic rocks, especially at the southern part of the island. A significant conclusion is that the rock described as volcanic in the previous map proved to be a fossiliferous limestone which includes micritic matrix of calcite with an insignificant amount of fossils. All the analogical and digital data and the results of the petrographic analysis were imported in a geodatabase specially designed for geological data. After the

  14. Studies by the U.S. Geological Survey on sources, transport, and fate of agricultural chemicals

    Science.gov (United States)

    Capel, Paul D.; Hamilton, Pixie A.; Erwin, Martha L.

    2004-01-01

    The U.S. Geological Survey's National Water-Quality Assessment (NAWQA) Program is assessing the sources, transport, and fate of chemicals applied to crops in agricultural basins across the Nation (referred to as "study units," see map). Chemicals selected for study include nutrients (nitrogen and phosphorus) and about 50 commonly used pesticides and their transformation products, including triazine and acetanilide herbicides such as atrazine and metolachlor, and organophosphorus insecticides such as chlorpyrifos and diazinon.

  15. Estimating the effect of current, previous and never use of drugs in studies based on prescription registries

    DEFF Research Database (Denmark)

    Nielsen, Lars Hougaard; Løkkegaard, Ellen; Andreasen, Anne Helms

    2009-01-01

    PURPOSE: Many studies which investigate the effect of drugs categorize the exposure variable into never, current, and previous use of the study drug. When prescription registries are used to make this categorization, the exposure variable possibly gets misclassified since the registries do not ca...

  16. Creation of a full color geologic map by computer: A case history from the Port Moller project resource assessment, Alaska Peninsula: A section in Geologic studies in Alaska by the U.S. Geological Survey, 1988

    Science.gov (United States)

    Wilson, Frederic H.

    1989-01-01

    Graphics programs on computers can facilitate the compilation and production of geologic maps, including full color maps of publication quality. This paper describes the application of two different programs, GSMAP and ARC/INFO, to the production of a geologic map of the Port Meller and adjacent 1:250,000-scale quadrangles on the Alaska Peninsula. GSMAP was used at first because of easy digitizing on inexpensive computer hardware. Limitations in its editing capability led to transfer of the digital data to ARC/INFO, a Geographic Information System, which has better editing and also added data analysis capability. Although these improved capabilities are accompanied by increased complexity, the availability of ARC/INFO's data analysis capability provides unanticipated advantages. It allows digital map data to be processed as one of multiple data layers for mineral resource assessment. As a result of development of both software packages, it is now easier to apply both software packages to geologic map production. Both systems accelerate the drafting and revision of maps and enhance the compilation process. Additionally, ARC/ INFO's analysis capability enhances the geologist's ability to develop answers to questions of interest that were previously difficult or impossible to obtain.

  17. Geologic framework for the national assessment of carbon dioxide storage resources: Arkoma Basin, Kansas Basins, and Midcontinent Rift Basin study areas: Chapter F in Geologic framework for the national assessment of carbon dioxide storage resources

    Science.gov (United States)

    Buursink, Marc L.; Craddock, William H.; Blondes, Madalyn S.; Freeman, Phillip A.; Cahan, Steven M.; DeVera, Christina A.; Lohr, Celeste D.

    2013-01-01

    2007 Energy Independence and Security Act (Public Law 110–140) directs the U.S. Geological Survey (USGS) to conduct a national assessment of potential geologic storage resources for carbon dioxide (CO2). The methodology used by the USGS for the national CO2 assessment follows that of previous USGS work. This methodology is non-economic and intended to be used at regional to subbasinal scales. This report identifies and contains geologic descriptions of three storage assessment units (SAUs) in Upper Cambrian to Mississippian sedimentary rocks within the Arkoma Basin study area, and two SAUs in Upper Cambrian to Mississippian sedimentary rocks within the Kansas Basins study area. The Arkoma Basin and Kansas Basins are adjacent with very similar geologic units; although the Kansas Basins area is larger, the Arkoma Basin is more structurally complex. The report focuses on the characteristics, specified in the methodology, that influence the potential CO2 storage resource in the SAUs. Specific descriptions of the SAU boundaries as well as their sealing and reservoir units are included. Properties for each SAU, such as depth to top, gross thickness, porosity, permeability, groundwater quality, and structural reservoir traps, are usually provided to illustrate geologic factors critical to the assessment. Although assessment results are not contained in this report, the geologic information herein was employed, as specified in the USGS methodology, to calculate a probabilistic distribution of potential storage resources in each SAU. The Midcontinent Rift Basin study area was not assessed, because no suitable storage formations meeting our size, depth, reservoir quality, and regional seal guidelines were found. Figures in this report show study area boundaries along with the SAU boundaries and cell maps of well penetrations through sealing units into the top of the storage formations. The cell maps show the number of penetrating wells within one-square mile and are

  18. Maternal and perinatal outcomes of delivery after a previous Cesarean section in Enugu, Southeast Nigeria: a prospective observational study.

    Science.gov (United States)

    Ugwu, George O; Iyoke, Chukwuemeka A; Onah, Hyacinth E; Egwuatu, Vincent E; Ezugwu, Frank O

    2014-01-01

    Obstetricians in developing countries appear generally reluctant to conduct vaginal delivery in women with a previous Cesarean because of lack of adequate facilities for optimal fetomaternal monitoring. To describe delivery outcomes among women with one previous Cesarean section at a tertiary hospital in Southeast Nigeria. This was a prospective observational study to determine maternal and perinatal outcomes of attempted vaginal birth after Cesarean sections (VBAC) following one previous Cesarean section. Analysis was done with SPSS statistical software version 17.0 for Windows using descriptive and inferential statistics at 95% level of confidence. Two thousand six hundred and ten women delivered in the center during the study period, of whom 395 had one previous Cesarean section. A total of 370 women with one previous Cesarean section had nonrecurrent indications, of whom 355 consenting pregnant women with one previous Cesarean section were studied. A majority of the women (320/355, 90.1%) preferred to have vaginal delivery despite the one previous Cesarean section. However, only approximately 54% (190/355) were found suitable for trial of VBAC, out of whom 50% (95/190 had successful VBAC. Ninety-five women (50.0%) had failed attempt at VBAC and were delivered by emergency Cesarean section while 35 women (9.8%) had emergency Cesarean section for other obstetric indications (apart from failed VBAC). There was no case of uterine rupture or neonatal and maternal deaths recorded in any group. Apgar scores of less than 7 in the first minute were significantly more frequent amongst women who had vaginal delivery when compared to those who had elective repeat Cesarean section (P=0.03). Most women who had one previous Cesarean delivery chose to undergo trial of VBAC, although only about half were considered suitable for VBAC. The maternal and fetal outcomes of trial of VBAC in selected women with one previous Cesarean delivery for non-recurrent indications were good

  19. Bibliography of U.S. Geological Survey studies of lakes and reservoirs; the first 100 years

    Science.gov (United States)

    Winter, Thomas C.

    1982-01-01

    For more than 100 years, the U.S. Geological Survey has pursued its mission of assessing and mapping the earth resources of the United States, including assessment of the Nation's water resources. Although the Survey has never been a water-management or development agency, it has assisted agencies that are responsible for such developments, and commonly provides data and information for such purposes. Because reservoirs are an intergral part of most water-development projects, the Survey has been involved in reservoir-related studies since the 1880's. The largest and longest involvement has centered on providing information on streamflows and sediment transport related to existing and proposed reservoirs. During the late 1940's, the Survey greatly expanded its activities in evaporation research. More recently, ground water, including bank storage, has gained increased attention. Most of these studies were related primarily to questions of water quantity, and the Survey continues to be involved in studies of physical hydrology. In addition, in response to the increased concern with environmental quality during the past 20 years, the number of Survey studies of the chemical and biological aspects of lakes and reservoirs have increased considerably. Prompted by the recent Centennial (1879-1979) of the U.S. Geological Survey, it is appropriate to assess the Survey's contributions to the hydrology of lakes and reservoirs. Both natural lakes and manmade reservoirs are included in this report. 1 This report includes studies in which lakes or reservoirs are the principal topics. It does not include reports of general water resources of an area in which lakes are discussed as part of that area. This report also does not include data reports in which the data are merely tabulated. The types of reports listed herein include studies of existing or proposed water bodies and associated fluxes of water to and from these water bodies. This report does not include geological or

  20. Geological Geophysical and structural studies in Mina Ratones (Pluton de Albala)

    International Nuclear Information System (INIS)

    Perez-Estaun, A.; Carbonell, R.; Marti, D.; Flecha, I.; Escuder Viruete, J.

    2002-01-01

    Mina Ratones environmental restoration project included petrological, structural,geophysical, hydrogeological and hydrogeochemical studies. The main objective of the geologic-structural and geophysical studies was the Albala granite structural characterization around the Mina Ratones uranium mine. The location of facies, fault zones (faults and dykes) as well as the distribution of some physical properties inside the rock massif was obtained for a granitic black of 900, 500, and 500 m. The geologic-structural and geophysical techniques applied to Mina Ratones provided a multidisciplinary approach for high resolution characterization of rock massif, and the structures potentially containing fluids,able to be applied to the hydrogeological modelling to a particular area. Geological studies included a detailed structural mapping of the area surrounding the mine (1:5,000 scale), the geometric, kinematics, and dynamics analysis of fractures of all scales, the petrology and geochemistry of fault rocks and altered areas surrounding fractures, and the microstructural studies of samples from surface and core lags. The construction of geostatistical models in two and three dimensions had helped to characterize the Mina Ratones rock massif showing the spatial distribution of fault zones, fracture intensity, granite composition heterogeneities, fluid-rock interaction zones, and physical properties. (Author)

  1. Study concerning the geological storage of radioactive waste in the Netherlands

    International Nuclear Information System (INIS)

    1987-03-01

    This report presents an intermediate state of affairs in the execution of the first stage of the program of research concerning the geological storage of nuclear waste in the Netherlands (OPLA-program). This first stage consists of desk studies and laboratory investigations in view of the judgement of the desirability of continuation of this program in eventual next steps with field research. 19 refs.; 11 figs.; 1 table

  2. Treatment of osteochondral defects of the talus with a metal resurfacing inlay implant after failed previous surgery: a prospective study

    NARCIS (Netherlands)

    van Bergen, C. J. A.; van Eekeren, I. C. M.; Reilingh, M. L.; Sierevelt, I. N.; van Dijk, C. N.

    2013-01-01

    We have evaluated the clinical effectiveness of a metal resurfacing inlay implant for osteochondral defects of the medial talar dome after failed previous surgical treatment. We prospectively studied 20 consecutive patients with a mean age of 38 years (20 to 60), for a mean of three years (2 to 5)

  3. Geologic and radiometric study of the Santa Rosalia area, Arizpe Department, Sonora Mexico

    International Nuclear Information System (INIS)

    Sanchez M, C.A.

    1977-01-01

    The importance of the radiometrical anomaly, discovered in the Santa Rosalia area, Arizpe Department, Sonota, is defined in this study through topographical and geological surveying of the area by the outline and systematical survey of rocks for sampling and registration of the radioactivity. Two radioactive anomalies were defined and called IIIA and IIIB, identifying the existence of secondary uranium minerals (Torbernite) in the IIIB anomaly. According to the results of the work which was carried out we can't deduce that both localities present signs of the existence of important uranium concentrations. We can conclude that the presence of uranium minerals obliges us to realize a more detailed exploration, suggesting the opening of little excavations and ditches and stretching out of the geochemical, geological and radiometrical exploration to adjacent areas. (author)

  4. An fMRI study of neuronal activation in schizophrenia patients with and without previous cannabis use

    Directory of Open Access Journals (Sweden)

    Else-Marie eLøberg

    2012-10-01

    Full Text Available Previous studies have mostly shown positive effects of cannabis use on cognition in patients with schizophrenia, which could reflect lower neurocognitive vulnerability. There are however no studies comparing whether such cognitive differences have neuronal correlates. Thus, the aim of the present study was to compare whether patients with previous cannabis use differ in brain activation from patients who has never used cannabis. The patients groups were compared on the ability to up-regulate an effort mode network during a cognitive task and down-regulate activation in the same network during a task-absent condition. Task-present and task-absent brain activation was measured by functional magnetic resonance neuroimaging (fMRI. Twenty-six patients with a DSM-IV and ICD-10 diagnosis of schizophrenia were grouped into a previous cannabis user group and a no-cannabis group. An auditory dichotic listening task with instructions of attention focus on either the right or left ear stimulus was used to tap verbal processing, attention and cognitive control, calculated as an aggregate score. When comparing the two groups, there were remaining activations in the task-present condition for the cannabis group, not seen in the no-cannabis group, while there was remaining activation in the task-absent condition for the no-cannabis group, not seen in the cannabis group. Thus, the patients with previous cannabis use showed increased activation in an effort mode network and decreased activation in the default mode network as compared to the no-cannabis group. It is concluded that the present study show some differences in brain activation to a cognitively challenging task between previous cannabis and no-cannabis schizophrenia patients.

  5. Underground geotechnical and geological investigations at Ekati Mine-Koala North: case study

    Science.gov (United States)

    Jakubec, Jaroslav; Long, Larry; Nowicki, Tom; Dyck, Darren

    2004-09-01

    Since 1998, BHP Billiton has mined diamonds at the Ekati Diamond Mine™ near Lac de Gras in the Northwest Territories of Canada. Current operations are based on mining multiple pipes by the open-pit method, but as some pits deepen, converting to underground mining is being considered. As a test of underground mining methods and to provide access to the lower elevations of the Panda and Koala pipes, the Koala North pipe is being developed for underground mining. Initially, the top 40 m of the pipe were mined as an open pit to provide grade information and a prepared surface for the transition to underground mining. Currently, Koala North is being developed as an open-benching, mechanized, trackless operation. Although the method was successfully used at several De Beers diamond operations in South Africa, it has never been tested in an Arctic environment. This case study describes basic geology, mining method layout and ongoing geological and geotechnical investigation. From the beginning of underground development, geotechnical daily routines have been fully integrated within the technical services department, which supports the operation. Geotechnical, geological and structural information obtained from underground mapping and core logging is compiled, processed, reviewed and analyzed on site by the geotechnical staff. Conclusions and recommendations are implemented as part of the operations in a timely manner. This ongoing ;live; process enables the operators to make the most efficient use of resources both for ground support and excavations as well as to address safety issues, which are the top priority.

  6. Contribution on the Northeastern Minas Gerais geologic-geochronologic study, Brazil

    International Nuclear Information System (INIS)

    Siga Junior, O.; Cordani, U.G.; Basei, M.A.S.; Teixeira, W.; Kawashita, K.

    1987-01-01

    This work demonstrates the potential of integrated Rb-Sr, K-Ar, and U-Pb determinations, when applied to basic regional geology. The different interpretative values of these methodologies contribute to the understanding of the tectonic processes developed in the south-eastern border of the Sao Francisco Craton (northeastern Minas Gerais). The Brazilian Orogenic Cycle is characterized in the area by the Salinas metasediments and the gneissic-migmatitic rocks of the eastern sector. Rb-Sr and U-Pb data indicate the generation of most or even all of these rocks in the 660-570 Ma, interval. No indications of ancient terrains were obtained, and previous ideas of a pervasive reworking of an Archean or Lower Proterozoic crust must be discarded. The K-Ar analyses indicate a crustal level in which temperature remained above 250 O C until at least 480 Ma. (author)

  7. Final inform of the studies carried out by the Geological Institute of Uruguay in the zone of Paso Severino of Santa Lucia small river

    International Nuclear Information System (INIS)

    1973-01-01

    This inform is about the geological conditions study carried out in Paso Severino zone of the Santa Lucia small river to make a dam to provide water to Montevideo. The techniques used were photo interpretation and general geological studies.

  8. Geologic framework for the national assessment of carbon dioxide storage resources: Williston Basin, Central Montana Basins, and Montana Thrust Belt study areas: Chapter J in Geologic framework for the national assessment of carbon dioxide storage resources

    Science.gov (United States)

    Buursink, Marc L.; Merrill, Matthew D.; Craddock, William H.; Roberts-Ashby, Tina L.; Brennan, Sean T.; Blondes, Madalyn S.; Freeman, P.A.; Cahan, Steven M.; DeVera, Christina A.; Lohr, Celeste D.; Warwick, Peter D.; Corum, Margo D.

    2014-01-01

    The 2007 Energy Independence and Security Act directs the U.S. Geological Survey (USGS) to conduct a national assessment of potential geologic storage resources for carbon dioxide (CO2). The methodology used by the USGS for the national CO2 assessment follows that of previous USGS work. This methodology is non-economic and is intended to be used at regional to sub-basinal scales.

  9. Study of heat diffusion in a granitic geologic formation of high level radioactive wastes

    International Nuclear Information System (INIS)

    Goldstein, S.; Juignet, N.

    1980-06-01

    Thermal study of granitic underground storage of vitrified high level radioactive wastes in a regular network of shafts and galleries. The aim is to show influence on temperature rise of the geologic formation of main parameters to define the storage zone and to determine the network dimension in function of the rock properties. Two models were studied allowing a rapid variation of geometrical and physical parameters. A numerical method using finite element method or Green functions were used for calculations. Temperatures are determined either for the whole storage site or a unit cell of the lattice [fr

  10. Changes in association between previous therapeutic abortion and preterm birth in Scotland, 1980 to 2008: a historical cohort study.

    Directory of Open Access Journals (Sweden)

    Clare Oliver-Williams

    Full Text Available Numerous studies have demonstrated that therapeutic termination of pregnancy (abortion is associated with an increased risk of subsequent preterm birth. However, the literature is inconsistent, and methods of abortion have changed dramatically over the last 30 years. We hypothesized that the association between previous abortion and the risk of preterm first birth changed in Scotland between 1 January 1980 and 31 December 2008.We studied linked Scottish national databases of births and perinatal deaths. We analysed the risk of preterm birth in relation to the number of previous abortions in 732,719 first births (≥24 wk, adjusting for maternal characteristics. The risk (adjusted odds ratio [95% CI] of preterm birth was modelled using logistic regression, and associations were expressed for a one-unit increase in the number of previous abortions. Previous abortion was associated with an increased risk of preterm birth (1.12 [1.09-1.16]. When analysed by year of delivery, the association was strongest in 1980-1983 (1.32 [1.21-1.43], progressively declined between 1984 and 1999, and was no longer apparent in 2000-2003 (0.98 [0.91-1.05] or 2004-2008 (1.02 [0.95-1.09]. A statistical test for interaction between previous abortion and year was highly statistically significant (p<0.001. Analysis of data for abortions among nulliparous women in Scotland 1992-2008 demonstrated that the proportion that were surgical without use of cervical pre-treatment decreased from 31% to 0.4%, and that the proportion of medical abortions increased from 18% to 68%.Previous abortion was a risk factor for spontaneous preterm birth in Scotland in the 1980s and 1990s, but the association progressively weakened and disappeared altogether by 2000. These changes were paralleled by increasing use of medical abortion and cervical pre-treatment prior to surgical abortion. Although it is plausible that the two trends were related, we could not test this directly as the data on

  11. Previous early antenatal service utilization improves timely booking: cross-sectional study at university of Gondar hospital, northwest Ethiopia.

    Science.gov (United States)

    Belayneh, Tadesse; Adefris, Mulat; Andargie, Gashaw

    2014-01-01

    Early booking of antenatal care (ANC) is regarded as a cornerstone of maternal and neonatal health care. However, existing evidence from developing countries indicate that lots of pregnant woman begin ANC booking lately. Objective. It was aimed to assess timing of ANC booking and associated factors among pregnant women attending ANC clinic at University of Gondar Hospital, 2013. An institution based cross-sectional study design was used to collect data with a face-to-face interview technique. Bivariate and multivariate analysis was used to identify associated factors for early ANC visit using SPSS version 20. From total women (N = 369) interviewed, 47.4% were timely booked. Mothers with younger age (AOR = 3.83, 95% CI: 1.89, 10.53), formal education (AOR = 1.06, 95% CI: 1.03, -7.61), previous early ANC visit (AOR = 2.39, 95% CI: 2.23, 9.86), and perceived ANC visit per pregnancy of four and greater were significantly associated with early ANC visit. Although late booking is a problem in this study, previous early utilization of ANC visit favors current timely booking. This indicates that the importance of early booking was appropriately addressed from previous visits. Counseling of timely booking during ANC visit should be strengthened. Moreover, empowering through education is also recommended.

  12. Effect of Acupressure, Acupuncture and Moxibustion in Women With Pregnancy-Related Anxiety and Previous Depression: A Preliminary Study.

    Science.gov (United States)

    Suzuki, Shunji; Tobe, Chiharu

    2017-06-01

    In this preliminary study, we examined the effect of acupressure, acupuncture and moxibustion (oriental treatments) to prevent of the relapse/deterioration of perinatal depression in women with pregnancy-related anxiety and previous depression. Between 2014 and 2016, there were 48 women with pregnancy-related anxiety and previous depression who had delivery at ≥ 22 weeks' gestation in our institute. Of these, oriental treatments were performed in eight and two women (totally 10, 21%) during pregnancy and postpartum, respectively. One of the 10 (10%) who received oriental treatments admitted depressive symptoms during pregnancy or postpartum, while 18 of the rest 38 who did not receive oriental treatments admitted depressive symptoms (47%, P = 0.065). The oriental treatments may be useful for pregnant women who need perinatal mental health care.

  13. [Cervical ripening after previous cesarean section with Foley catheter: A prospective study of 41 patients].

    Science.gov (United States)

    Lamourdedieu, C; Gnisci, A; Marcelli, M; Heckenroth, H; Gamerre, M; Agostini, A

    2015-05-01

    Effectiveness of cervical ripening with Foley catheter for patients requiring labor induction with a previous cesarean section and unfavorable cervical conditions. Prospective unicentric study conducted between 1 April 2011 and 31 October 2013 on 41 patients with medical indication for labor induction with a Bishop's scorecesarean section. Outcomes evaluated were mode of delivery, Bishop's score variations and maternal or neonatal complications. Cervical ripening was performed in 39 patients and 17 (43.5%) were delivered vaginally. A total of 24/39 (61.5%) patients were put into work and 10/39 (25.6%) came into work immediately after removal of the Foley catheter. The average score improvement Bishop was 2.7±0.6 points. No maternal or fetal complication was reported. Foley catheter is an interesting procedure in patients with previous cesarean section and unfavorable cervical conditions requiring labor induction. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  14. Geotechnical support and topical studies for nuclear waste geologic repositories: Annual report, fiscal year 1987

    International Nuclear Information System (INIS)

    1988-01-01

    This multidisciplinary project was initiated in fiscal year 1986. It comprises 11 reports in two major interrelated tasks: The technical assistance part of the project includes reviewing the progress of the major projects in the DOE Office of Civilian Radioactive waste Management (OCRWM) Program and advising the Engineering and Geotechnology Division on significant technical issues facing each project; analyzing geotechnical data, reports, tests, surveys and plans for the different projects; reviewing and commenting on major technical reports and other program documents such as Site Characterization Plans (SCP) and Study Plans; and providing scientific and technical input at technical meetings. The topical studies activity comprises studies on scientific and technical ions and issues of significance to in-situ testing, test analysis methods, and site characterization of nuclear waste geologic repositories. The subjects of study were selected based on discussions with DOE staff. One minor topic is a preliminary consideration and planning exercise for postclosure monitoring studies. The major task, with subtasks involving various geoscience disciplines, is a study of the mechanical, hydraulic, geophysical and geochemical properties of fractures in geologic rock masses

  15. Feasibility studies for alpha waste disposal on geological formations in France

    International Nuclear Information System (INIS)

    Jaouen, C.; Boulanger, A.

    1986-01-01

    Since 1977, SGN has been involved in many feasibility studies and consultant works in the fields of HLW storages. Starting as nuclear consultant company in the KBS review of the long term storage of HLW, SGN and GEOSTOCK were entrusted in 1978 by the EEC for the basic design and evaluation of the deep storage into granite rock of HLW, followed by a participation in the thermal sensitivity study of such a storage. The cooperation with GEOSTOCK was first extended in 1981 to a preliminary study of HLW storage conditions in granite for a Japanese company, and then in France for several feasibility studies of HLW and TRU waste geological disposal. Three kinds of scenarios have been forecasted and evaluated in the case of vitrified HLW storage, allowing the thermal power to be decreased and the whole management scheme to be optimized. More recently, SGN participation to French engineering studies has been extended by ANDRA to the TRU waste repository evaluation. All these works for French authorities have been performed in a close connection with several specialized departments in the CEA group, and with the help of geological specialists, under the leadership of ANDRA [fr

  16. Feasibility studies for alpha waste disposal on geological formations in France

    International Nuclear Information System (INIS)

    Jaouen, C.; Boulanger, A.

    1985-01-01

    Since 1977, SGN has been involved in many feasibility studies and consultant works in the fields of HLW storages. Starting as nuclear consultant company in the KBS review of the long term storage of HLW, SGN and Geostock were entrusted in 1978 by the EEC for the basic design and evaluation of the deep storage into granite rock of HLW, followed by a participation in the thermal sensitivity study of such a storage. The cooperation with Geostock was first extended in 1981 to a preliminary study of HLW storage conditions in granite for a Japanese company, and then in France for several feasibility studies of HLW and TRU waste geological disposal. Three kinds of scenarios have been forecasted and evaluated in the case of vitrified HLW storage, allowing the thermal power to be decreased and the whole management scheme to be optimized. More recently, SGN participation to French engineering studies has been extended by ANDRA to the TRU waste repository evaluation. All these works for French authorities have been performed in a close connection with several specialized departments in the CEA group, and with the help of geological specialists, under the leadership of ANDRA [fr

  17. Hydrologic studies of the U.S. Geological Survey related to coal development on Colorado

    Science.gov (United States)

    ,

    1976-01-01

    This report summarizes the hydrologic studies related to coal development being conducted by the U.S. Geological Survey in the State of Colorado. The objective of the hydrologic data-acquisition program is to collect surface-water quality and quantity data and ground-water level records. These data are needed to define predevelopment conditions and to monitor the effects of construction and operation of coal mines and waste-disposal areas. Data-acquisition activities related to coal development in Colorado have concentrated on the Yampa River basin. A description of the hydrologic data-acquisition activities, including parameters collected and frequency of collection, precedes the summaries of the three interpretive studies currently in progress. Each study summary consists of the project title, definition of the problem being studied, objective of the study, approach of the study, and when known, the schedule for completion of the study and proposed report products resulting from the study. (Woodard-USGS)

  18. Data base dictionary for the Oak Ridge Reservation Hydrology and Geology Study Groundwater Data Base

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, B.K.

    1993-04-01

    The Oak Ridge Reservation Hydrology and Geology Study (ORRHAGS) Groundwater Data Base has been compiled to consolidate groundwater data from the three US Department of Energy facilities located on the Oak Ridge Reservation: the Oak Ridge K-25 Site, the Oak Ridge National Laboratory, and the Oak Ridge Y-12 Plant. Each of these facilities maintains its own groundwater and well construction data bases. Data were extracted from the existing data bases, converted to a consistent format, and integrated into the ORRHAGS Groundwater Data Base structures. This data base dictionary describes the data contained in the ORRHAGS Groundwater Data Base and contains information on data base structure, conventions, contents, and use.

  19. Intercomparison NaI(Tl) and HPGe spectrometry to studies of natural radioactivity on geological samples.

    Science.gov (United States)

    Hung, Nguyen Quoc; Chuong, Huynh Dinh; Vuong, Le Quang; Thanh, Tran Thien; Tao, Chau Van

    2016-11-01

    In this study, in situ gamma spectra using NaI(Tl) detector have been compared with the laboratory measurements by using HPGe detector on geological samples. The results for measuring naturally occurring terrestrial gamma radiation of 4 0 K and the decay series of 232 Th and, 238 U respectively of both detectors show a maximum deviation about 5%. The mass activities series from both detectors were checked for coherence using proficiency test procedure from the International Atomic Energy Agency. The reliability and precision pass for final scores for all the analytical determinations of are received "acceptable" for all radionuclides. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Previous experiences and emotional baggage as barriers to lifestyle change - a qualitative study of Norwegian Healthy Life Centre participants.

    Science.gov (United States)

    Følling, Ingrid S; Solbjør, Marit; Helvik, Anne-S

    2015-06-23

    Changing lifestyle is challenging and difficult. The Norwegian Directorate of Health recommends that all municipalities establish Healthy Life Centres targeted to people with lifestyle issues. Little is known about the background, experiences and reflections of participants. More information is needed about participants to shape effective lifestyle interventions with lasting effect. This study explores how participants in a lifestyle intervention programme describe previous life experiences in relation to changing lifestyle. Semi-structured qualitative in-depth interviews were performed with 23 participants (16 women and 7 men) aged 18 - 70 years. The data were analysed using systematic text condensation searching for issues describing participants' responses, and looking for the essence, aiming to share the basis of life-world experiences as valid knowledge. Participants identified two main themes: being stuck in old habits, and being burdened with emotional baggage from their previous negative experiences. Participants expressed a wish to change their lifestyles, but were unable to act in accordance with the health knowledge they possessed. Previous experiences with lifestyle change kept them from initiating attempts without professional assistance. Participants also described being burdened by an emotional baggage with problems from childhood and/or with family, work and social life issues. Respondents said that they felt that emotional baggage was an important explanation for why they were stuck in old habits and that conversely, being stuck in old habits added load to their already emotional baggage and made it heavier. Behavioural change can be hard to perform as psychological distress from life baggage can influence the ability to change. The study participants' experience of being stuck in old habits and having substantial emotional baggage raises questions as to whether or not Healthy Life Centres are able to help participants who need to make a lifestyle

  1. Hydrothermal diamond-anvil cell: Application to studies of geologic fluids

    Science.gov (United States)

    Chou, I.-Ming

    2003-01-01

    The hydrothermal diamond-anvil cell (HDAC) was designed to simulate the geologic conditions of crustal processes in the presence of water or other fluids. The HDAC has been used to apply external pressure to both synthetic and natural fluid inclusions in quartz to minimize problems caused by stretching or decrepitation of inclusions during microthermometric analysis. When the HDAC is loaded with a fluid sample, it can be considered as a large synthetic fluid inclusion and therefore, can be used to study the PVTX properties as well as phase relations of the sample fluid. Because the HDAC has a wide measurement pressure-temperature range and also allows in-situ optical observations, it has been used to study critical phenomena of various chemical systems, such as the geologically important hydrous silicate melts. It is possible, when the HDAC is combined with synchrotron X-ray sources, to obtain basic information on speciation and structure of metal including rare-earth elements (REE) complexes in hydrothermal solutions as revealed by X-ray absorption fine structure (XAFS) spectra. Recent modifications of the HDAC minimize the loss of intensity of X-rays due to scattering and absorption by the diamonds. These modifications are especially important for studying elements with absorption edges below 10 keV and therefore particularly valuable for our understanding of transport and deposition of first-row transition elements and REE in hydrothermal environments.

  2. Outcomes of induction of labour in women with previous caesarean delivery: a retrospective cohort study using a population database.

    Directory of Open Access Journals (Sweden)

    Sarah J Stock

    Full Text Available There is evidence that induction of labour (IOL around term reduces perinatal mortality and caesarean delivery rates when compared to expectant management of pregnancy (allowing the pregnancy to continue to await spontaneous labour or definitive indication for delivery. However, it is not clear whether IOL in women with a previous caesarean section confers the same benefits. The aim of this study was to describe outcomes of IOL at 39-41 weeks in women with one previous caesarean delivery and to compare outcomes of IOL or planned caesarean delivery to those of expectant management.We performed a population-based retrospective cohort study of singleton births greater than 39 weeks gestation, in women with one previous caesarean delivery, in Scotland, UK 1981-2007 (n = 46,176. Outcomes included mode of delivery, perinatal mortality, neonatal unit admission, postpartum hemorrhage and uterine rupture. 40.1% (2,969/7,401 of women who underwent IOL 39-41 weeks were ultimately delivered by caesarean. When compared to expectant management IOL was associated with lower odds of caesarean delivery (adjusted odds ratio [AOR] after IOL at 39 weeks of 0.81 [95% CI 0.71-0.91]. There was no significant effect on the odds of perinatal mortality but greater odds of neonatal unit admission (AOR after IOL at 39 weeks of 1.29 [95% CI 1.08-1.55]. In contrast, when compared with expectant management, elective repeat caesarean delivery was associated with lower perinatal mortality (AOR after planned caesarean at 39 weeks of 0.23 [95% CI 0.07-0.75] and, depending on gestation, the same or lower neonatal unit admission (AOR after planned caesarean at 39 weeks of 0.98 [0.90-1.07] at 40 weeks of 1.08 [0.94-1.23] and at 41 weeks of 0.77 [0.60-1.00].A more liberal policy of IOL in women with previous caesarean delivery may reduce repeat caesarean delivery, but increases the risks of neonatal complications.

  3. Birth outcome in women with previously treated breast cancer--a population-based cohort study from Sweden.

    Directory of Open Access Journals (Sweden)

    Kristina Dalberg

    2006-09-01

    Full Text Available Data on birth outcome and offspring health after the appearance of breast cancer are limited. The aim of this study was to assess the risk of adverse birth outcomes in women previously treated for invasive breast cancer compared with the general population of mothers.Of all 2,870,932 singleton births registered in the Swedish Medical Birth Registry during 1973-2002, 331 first births following breast cancer surgery--with a mean time to pregnancy of 37 mo (range 7-163--were identified using linkage with the Swedish Cancer Registry. Logistic regression analysis was used. The estimates were adjusted for maternal age, parity, and year of delivery. Odds ratios (ORs and 95% confidence intervals (CIs were used to estimate infant health and mortality, delivery complications, the risk of preterm birth, and the rates of instrumental delivery and cesarean section. The large majority of births from women previously treated for breast cancer had no adverse events. However, births by women exposed to breast cancer were associated with an increased risk of delivery complications (OR 1.5, 95% CI 1.2-1.9, cesarean section (OR 1.3, 95% CI 1.0-1.7, very preterm birth (<32 wk (OR 3.2, 95% CI 1.7-6.0, and low birth weight (<1500 g (OR 2.9, 95% CI 1.4-5.8. A tendency towards an increased risk of malformations among the infants was seen especially in the later time period (1988-2002 (OR 2.1, 95% CI 1.2-3.7.It is reassuring that births overall were without adverse events, but our findings indicate that pregnancies in previously treated breast cancer patients should possibly be regarded as higher risk pregnancies, with consequences for their surveillance and management.

  4. High-level waste canister corrosion studies pertinent to geologic isolation

    International Nuclear Information System (INIS)

    Braithwaite, J.W.; Molecke, M.A.

    1978-12-01

    The compatibility of candidate high-level waste (HLW) canister materials with deep geologic isolation environments is addressed. Results are presented which are applicable to the following repositories or test facilities: bedded and domed salt, sub-seabed sediment, and various types of hardrock. Such studies are an essential portion of the technological basis for terminal waste management. These studies will identify HLW canister or overpack materials satisfying appropriate requirements for barrier lifetime. Mechanical properties, as well as constraints on cost and consumption of critically limited materials, are also selection criteria. Lifetime objectives range from a minimum of several years for retrievability constraints up to several hundred years for retardation of near-field interactions (e.g., waste form leaching with potential radionuclide release to the geosphere) during the period of greatest HLW thermal output. A review of present and prior applicable corrosion results is presented. However, emphasis is on the results obtained from current laboratory and in situ HLW canister/corrosion programs at Sandia Laboratories. The effects of multiple variables on corrosion susceptibility and rates are briefly discussed and some applicable data given. It is possible to provide a canister/overpack barrier which can survive geologic isolation environments for periods of several hundred years

  5. An integrated approach to the study of catastrophic debris-flows: geological hazard and human influence

    Science.gov (United States)

    Del Ventisette, C.; Garfagnoli, F.; Ciampalini, A.; Battistini, A.; Gigli, G.; Moretti, S.; Casagli, N.

    2012-09-01

    On 1 October 2009, a prolonged and intense rainstorm triggered hundreds of landslides (predominantly debris flows) in an area of about 50 km2 in the north-eastern sector of Sicily (Italy). Debris flows swept the highest parts of many villages and passed over the SS114 state highway and the Messina-Catania railway, causing more than 30 fatalities. This region has a high relief, due to recent uplift. The peculiar geological and geomorphological framework represents one of the most common predisposing causes of rainstorm-triggered debris flows. This paper deals with the geological and hydro-geomorphological studies performed as a part of the post-disaster activities operated in collaboration with Civil Protection Authority, with the aim at examining landslides effects and mechanisms. The data were elaborated into a GIS platform, to evaluate the influence of urbanisation on the drainage pattern, and were correlated with the lithological and structural framework of the area. Our study points at the evaluation of the volume involved, the detection of triggering mechanisms and the precise reconstruction of the influence of urbanisation as fundamental tools for understanding the dynamics of catastrophic landslides. This kind of analysis, including all the desirable approaches for the correct management of debris flow should be the starting point for robust urban planning.

  6. The study of fracture mineralization and relationship with high level radioactive waste of deep geological repository

    International Nuclear Information System (INIS)

    Reyes, Cristina N.

    2003-01-01

    Extensive investigations of the Ordovician, Dinantian and Permo-Triassic rocks of the Sellafield area of northwest England were undertaken by United Kingdom Nirex Ltd. as a possible national site for geological disposal of intermediate and low-level radioactive waste. Very detailed studies of fracture mineralisation at Sellafield were thus put in hand by Nirex Ltd. and the results summarised by the British Geological Survey. Deep (up to 2 km) boreholes were put down with excellent core recovery. It is generally agreed that the most significant pathway for the escape of all but a very few radionuclides is by solution in and advection of groundwater. In this context, rock fracture systems are particularly important because they offer a potentially rapid pathway to the surface and the biosphere. One striking aspect of this work is that the fracture mineralisation seemingly records major and rapid fluctuations in redox conditions -sometimes during apparently continuous precipitation of cements (ferroan and non-ferroan calcites, dolomite). Carbonate cements record variations in Fe 2+ availability. Fe(III) precipitates also as oxide (hematite) and Fe(II) as sulphide (pyrite). This study focuses on these elements and valence states and also on Mn; another element susceptible to redox controls but known to respond differently from Fe. Shallow sub-surface stores or repositories would be more likely to have oxidising or fluctuating redox conditions. The mineralisation sequences documented at Sellafield are potentially promising in this context. Ferroan carbonate cements are sensitive indicators of later movement of oxidising ground waters. (author)

  7. Study on establishing database system for marine geological and geophysical data 1

    Energy Technology Data Exchange (ETDEWEB)

    Han, Hyun Chul; Bahng, Hyo Ky; Lee, Chi Won; Kang, Jung Seock; Chang, Se Won; Lee, Ho Young [Korea Inst. of Geology Mining and Materials, Taejon (Korea, Republic of); Park, Soo Chul [Chungnam National University, Taejon (Korea, Republic of)

    1995-12-01

    Most marine geological and geophysical data collected from the institutes of Korea are an analogue type, and stored in several data acquisition institutes according to their own data management systems and input formats. Thus, if someone wants to use the data, he must visit institute(s) to collect the data. It is also necessary to manipulate the collected data based on the user`s own data management system because data input formats differ from each institute. Consequently, it requires lots of time to do searching, managing and analyzing the data. The purpose of the study, therefore, is to establish database system for the standardization of the data input formats and to develop the data output conversion software for the commonly used database management system. Marine geological and geophysical data input formats are set up through the detailed analyses for the input formats used in the domestic as well as foreign countries. PC-based output conversion software for the bathymetry, gravity and magnetic data is also developed. Thus, if all institutes use the data input formats introduced in this study, it is possible to minimize the redundancy, to keep the consistency, and to make a standardization of data. (author). 6 refs., 22 figs., 10 tabs.

  8. U.S. Geological Survey geohydrologic studies and monitoring at the Idaho National Laboratory, southeastern Idaho

    Science.gov (United States)

    Bartholomay, Roy C.

    2017-09-14

    BackgroundThe U.S. Geological Survey (USGS) geohydrologic studies and monitoring at the Idaho National Laboratory (INL) is an ongoing, long-term program. This program, which began in 1949, includes hydrologic monitoring networks and investigative studies that describe the effects of waste disposal on water contained in the eastern Snake River Plain (ESRP) aquifer and the availability of water for long-term consumptive and industrial use. Interpretive reports documenting study findings are available to the U.S. Department of Energy (DOE) and its contractors; other Federal, State, and local agencies; private firms; and the public at https://id.water.usgs.gov/INL/Pubs/index.html. Information contained within these reports is crucial to the management and use of the aquifer by the INL and the State of Idaho. USGS geohydrologic studies and monitoring are done in cooperation with the DOE Idaho Operations Office.

  9. Non-destructive spectrometry methods to study the distribution of archaeological and geological chert samples.

    Science.gov (United States)

    Olivares, Maitane; Tarriño, Andoni; Murelaga, Xabier; Baceta, Juan Ignacio; Castro, Kepa; Etxebarria, Nestor

    2009-08-01

    The study of lithic raw materials recovered from archaeological sites offers relevant data on source catchment areas. Additionally, it can provide first hand information on artefact displacement, interchange networks and it can reflect the way in which the artefacts were employed. In order to characterize geological and archaeological chert samples and with the aim of finding an analytical fingerprint infrared and Raman spectroscopies were used for molecular analysis and X-ray Fluorescence spectrometry for elemental analysis. In this work, different chert samples coming from several localities with geological and archaeological importance from the Basque Country have been collected and analysed. As a consequence, Raman spectroscopy allowed to distinguish between alpha-quartz and moganite in chert samples without organic matter and it is suggested that the ratio of those two components is related to the source of the chert. In addition, the impurities that appear in the samples (CaCO(3), iron oxides and organic matter) can open new features to distinguish the samples and in this way, it would be possible to discuss the use and transport of the lithic artifacts from the sources to the final settlements.

  10. STUDY OF INFLUENCE OF PREVIOUS ORAL APPLICATION OF DIPHTHERIA ANTIGENIC PREPARATIONS ON RABBIT ALLERGIC REACTION FORMING AFTER SKIN TEST

    Directory of Open Access Journals (Sweden)

    Babych YeM

    2013-03-01

    Full Text Available It’s studied an influence of previous oral application of diphtheria antigenic preparations on allergic inflammation forming after skin test. It’s used destroyed by ultrasonic microbe cells C.diphtheriae var. gravis tox+ massachusets, free from destroyed cells by the use of centrifugation supernatant and refined concentrated diphteria toxoid. Experimental rabbits are fed to 3,5 ml of one of antigenic preparations (the total protein dose is 33,6 mg, control ones are fed to saline. In a week all animals were injected intracutaneously 0,2 ml each of corresponding antigenic preparation. The findings testify to decreasing manifestation tendency of rabbit skin reactions on antigenic preparations.

  11. Studies on the immune response of previously infected lambs to vaccination with the radiation attenuated Dictyocaulus filaria vaccine

    International Nuclear Information System (INIS)

    Dhar, D.N.; Sharma, R.L.

    1976-01-01

    The immune response of lambs infected with the lungworm, Dictyocaulus filaria to vaccination with the radiation attenuated D.filaria vaccine was studied under experimental conditions. Healthy, un-infected lambs, 4-6 months of age were randomly distributed into three groups. Group one lambs were previously exposed to single or trickle infections of D.filaria before being vaccinated, group two lambs were vaccinated only whereas the group three lambs received neither infection nor were vaccinated. All the lambs were subsequently challanged with normal infective D.filaria larvae. The results of the experiment indicate that the vaccine confers very little or practically no immunity in lambs already exposed to the infection. The significance of these findings in the use of the vaccine for the control of lungworm disease in sheep under field conditions is discussed. (author)

  12. The suitability of XRF analysis for compositional classification of archaeological ceramic fabric: A comparison with a previous NAA study

    Energy Technology Data Exchange (ETDEWEB)

    Padilla, R. [Centro de Aplicaciones Tecnologicas y Desarrollo Nuclear (CEADEN), Laboratorio de Analisis Quimico, Calle 30 no. 502, Playa, Ciudad Habana (Cuba)]. E-mail: roman.padilla@infomed.sld.cu; Espen, P. van [University of Antwerp (Belgium); Torres, P.P. Godo [Centro de Antropologia, Havana (Cuba)

    2006-02-03

    The main drawbacks of EDXRF techniques, restricting its more frequent use for the specific purpose of compositional analysis of archaeological ceramic fabric, have been the insufficient sensitivity to determine some important elements (like Cr, REE, among others), a somewhat worse precision and the inability to perform standard-less quantitative procedures in the absence of suitable certified reference materials (CRM) for ceramic fabric. This paper presents the advantages of combining two energy dispersive X-ray fluorescence methods for fast and non-destructive analysis of ceramic fabric with increased sensitivity. Selective polarized excitation using secondary targets (EDPXRF) and radioisotope excitation (R-XRF) using a {sup 241}Am source. The analytical performance of the methods was evaluated by analyzing several CRM of sediment type, and the fitness for the purpose of compositional classification was compared with that obtained by using Instrumental Neutron Activation Analysis in a previous study of Cuban aborigine pottery.

  13. Treatment satisfaction with paliperidone extended-release tablets: open-label study in schizophrenia patients dissatisfied with previous antipsychotic medication

    Directory of Open Access Journals (Sweden)

    Yang FD

    2017-04-01

    Full Text Available Fu De Yang,1 Juan Li,1 Yun Long Tan,1 Wei Ye Liang,1 Rongzhen Zhang,1 Ning Wang,1 Wei Feng,1 Shangli Cai,2 Jian Min Zhuo,2 Li Li Zhang2 1Beijing Hui-Long-Guan Hospital, 2Department of Medical Affairs, Xian Janssen Pharmaceutical Ltd, Beijing, People’s Republic of China Objective: The aim of this study was to evaluate the changes in treatment satisfaction after switching to paliperidone extended-release (ER in Chinese schizophrenia patients dissatisfied with their previous antipsychotic treatment.Methods: In this 8-week, open-label, single-arm, multicenter, prospective study, 1,693 patients dissatisfied with previous antipsychotic medication were enrolled and switched to paliperidone ER tablets (3–12 mg/d based on clinical judgment. The primary efficacy end point was change in Medication Satisfaction Questionnaire (MSQ score from baseline to week 8. The secondary end points included percentage of patients with MSQ score ≥4, as well as changes in Clinical Global Improvement-Severity (CGI-S and Personal and Social Performance (PSP scores.Results: MSQ scores increased significantly from baseline (mean [standard deviation {SD}]: 2.48 [0.55] to week 8 (5.47 [0.89], P<0.0001; primary end point, full analysis set. The percentage of patients with MSQ score ≥4 was 95.9% at week 8, indicating that most of the patients were satisfied with their treatment. Significant (P<0.0001 improvements from baseline to week 8 were noted in CGI-S score (2.37 [1.20] and PSP score (25.5 [15.0]. A total of 174 (10.28% patients experienced adverse events (AEs. The most common (>10 patients events were extrapyramidal disorder (n=84, 4.96%, poor quality sleep (n=18, 1.06% and akathisia (n=13, 0.77%. The majority of AEs were mild to moderate in severity. No deaths occurred.Conclusion: Treatment satisfaction improved after switching to paliperidone ER from the previous antipsychotic in Chinese patients with schizophrenia. Keywords: atypical antipsychotics, open label

  14. Evaluation of questionnaire-based information on previous physical work loads. Stockholm MUSIC 1 Study Group. Musculoskeletal Intervention Center.

    Science.gov (United States)

    Torgén, M; Winkel, J; Alfredsson, L; Kilbom, A

    1999-06-01

    The principal aim of the present study was to evaluate questionnaire-based information on past physical work loads (6-year recall). Effects of memory difficulties on reproducibility were evaluated for 82 subjects by comparing previously reported results on current work loads (test-retest procedure) with the same items recalled 6 years later. Validity was assessed by comparing self-reports in 1995, regarding work loads in 1989, with worksite measurements performed in 1989. Six-year reproducibility, calculated as weighted kappa coefficients (k(w)), varied between 0.36 and 0.86, with the highest values for proportion of the workday spent sitting and for perceived general exertion and the lowest values for trunk and neck flexion. The six-year reproducibility results were similar to previously reported test-retest results for these items; this finding indicates that memory difficulties was a minor problem. The validity of the questionnaire responses, expressed as rank correlations (r(s)) between the questionnaire responses and workplace measurements, varied between -0.16 and 0.78. The highest values were obtained for the items sitting and repetitive work, and the lowest and "unacceptable" values were for head rotation and neck flexion. Misclassification of exposure did not appear to be differential with regard to musculoskeletal symptom status, as judged by the calculated risk estimates. The validity of some of these self-administered questionnaire items appears sufficient for a crude assessment of physical work loads in the past in epidemiologic studies of the general population with predominantly low levels of exposure.

  15. Studies of natural analogues and geological systems. Their importance to performance assessment

    International Nuclear Information System (INIS)

    Brandberg, F.; Grundfelt, B.; Hoeglund, L.O.; Skagius, K.; Karlsson, Fred; Smellie, J.

    1992-04-01

    This review has involved studies of natural analogues and natural geological systems leading to the identification and quantification of processes and features of importance to the performance and safety of repositories for radioactive waste. The features and processes selected for the study comprise general geochemical issues related to the performance of the near- and of the far-field, the performance and durability of construction materials and the effects of glaciation. For each of these areas a number of potentially important processes for repository performance have been described, and evidence for their existence, as well as quantification of parameters of models describing the processes, have been sought from major natural analogue studies and site investigations. The review has aimed at covering a relatively broad range of issues at the expense of in-depth analysis. The quantitative data presented are in most cases compilations of data from the literature; in a few cases results of evaluations made within the current project are included. The results of the study show that studies of natural analogues and natural geological systems have provided significant information regarding many issues of importance to repository performance. In several cases the evidence from natural analogues has demonstrated that processes assumed to take place in repositories actually occur in natural systems or under conditions similar to those predicted to prevail in a future repository. One example of such a process is coprecipitation of fission products and ferric oxyhydroxides as an analogue to corrosion products from a steel canister. In addition, the study of concentration gradients of uranium and other trace substances in the rock surrounding groundwater conduits confirm that matrix diffusion occurs in nature and that the diffusivities in the rock matrix measured in the laboratory are consistent with the observations in nature

  16. A comprehensive study of oculocutaneous albinism type 1 reveals three previously unidentified alleles on the TYR gene.

    Science.gov (United States)

    Lin, Yu-Ying; Wei, Ai-Hua; He, Xin; Zhou, Zhi-Yong; Lian, Shi; Zhu, Wei

    2014-01-01

    Oculocutaneous albinism (OCA) is a congenital genetic disorder characterized by defects in melanin production. OCA type 1 (OCA1) is the most serious and common type of OCA. This study characterized mutations associated with OCA1 in a series of Chinese patients. We recruited 41 unrelated patients with OCA and 100 healthy subjects from the Chinese Han population. Genomic DNA was extracted from their blood samples. Mutational analysis of tyrosinase (TYR) genes was conducted using polymerase chain reaction (PCR) and direct sequencing, specifically to test the 100 control subjects and exclude the possibility of polymorphism. Mutational analysis and bioinformatics study were performed in TYR mutations. Among the 24 (58.5%) patients with OCA1, 21 different TYR mutations were identified, including three previously unidentified alleles (PUAs): one frameshift mutation (c.216delA) and two missense mutations (A241T and N364K). The proband mutation A241T carries three possible mutations in complex OCA. The findings of this study expand current knowledge and data of mutations associated with OCA1 in China and allow us to estimate or explore the mutation spectrum and relative frequencies of the TYR gene in the Chinese population.

  17. Barriers to postpartum screening for type 2 diabetes: a qualitative study of women with previous gestational diabetes.

    Science.gov (United States)

    Rafii, Forough; Rahimparvar, Seyedeh Fatemeh Vasegh; Mehrdad, Neda; Keramat, Afsaneh

    2017-01-01

    Risk of developing type 2 diabetes is increased in women with previous gestational diabetes mellitus (GDM). Postpartum glycemic screening is recommended in women with recent GDM. But this screening rate is low and the reasons are unclear. The aim of this study was to explore the experiences of Iranian women with recent GDM on barriers of postpartum screening for diabetes. This qualitative study was conducted in Tehran, Iran in 2016. Semi-structured interview was used for data collection. 22 women with recent GDM were interviewed. These women gave birth in Tehran hospitals at a minimum of 6 months before interview. The missed screening defined as not attending to laboratory for Fasting Blood Sugar and/or Oral Glucose Tolerance Test, 6 week to 6 month after their child birthing. The data was analyzed by content analysis method. Themes and sub-themes that illustrated the barriers to postpartum diabetes screening were: inadequate education (about developing diabetes in the future, implementation of the screening, and glucometer validity in diagnosis of diabetes), perceiving the screening as difficult (feeling comfortable with the glucometer, poor laboratory conditions, issues related to the baby/babies, and financial problems), improper attitudes toward the screening (unwilling to get diagnosed, not giving priority to oneself, having false beliefs) and procrastination (gap to intention and action, self-deception and self-regulation failure). Women with recent GDM reported several barriers for postpartum diabetes screening. This study help to develop the evidence-based interventions for improving this screening rate.

  18. Value and reliability of findings from previous epidemiologic studies in the assessment of radiation-related cancer risks. Pt. 3

    International Nuclear Information System (INIS)

    Frasch, G.; Martignoni, K.

    1990-01-01

    The theories put forward here are predominantly based on pooled data from previous studies in a number of cohorts made up by mostly non-average individuals. These studies were carried out by various researchers and differed in procedures and aims. Factors of major importance to the validity and reliability of the conclusions drawn from this study are pointed out. In one chapter some light is thrown on factors known to bear a relation to the incidence of radiation-induced cancer of the breast, even though at present this can only very vaguely be described on a quantitative basis. These factors include fractionated dose regimens, pregnancies and parturitions, menarche, menopause, synergisms as well as secondary cancer of the breast. The available body of evidence suggests that exposure of each of 1 million women to a dose of 10 mGy (rad) can be linked with approx. 3 additional cases of mammary cancer reported on an average per year after the latency period. The fact that there is some statistical scatter around this value is chiefly attributable to age-related causes at the beginning of exposure. Differences in ethnic and cultural characteristics between the populations investigated appeared to be less important here. (orig./MG) [de

  19. A Flexible-Dose Study of Paliperidone ER in Patients With Nonacute Schizophrenia Previously Treated Unsuccessfully With Oral Olanzapine

    Science.gov (United States)

    KOTLER, MOSHE; DILBAZ, NESRIN; ROSA, FERNANDA; PATERAKIS, PERIKLIS; MILANOVA, VIHRA; SMULEVICH, ANATOLY B.; LAHAYE, MARJOLEIN

    2016-01-01

    Objective: The goal of this study was to explore the tolerability, safety, and treatment response of switching from oral olanzapine to paliperidone extended release (ER). Methods: Adult patients with nonacute schizophrenia who had been treated unsuccessfully with oral olanzapine were switched to flexible doses of paliperidone ER (3 to 12 mg/d). The primary efficacy outcome was a ≥20% improvement in Positive and Negative Syndrome Scale (PANSS) total scores from baseline to endpoint for patients who switched medications because of lack of efficacy with olanzapine and noninferiority versus previous olanzapine treatment (mean endpoint change in PANSS total scores vs. baseline of ≤5 points) for patients who switched for reasons other than lack of efficacy. Safety and tolerability were assessed by monitoring adverse events, extrapyramidal symptoms, and weight change. Results: Of 396 patients, 65.2% were men, mean age was 40.0±12.0 years, and 75.5% had paranoid schizophrenia. Among the patients whose main reason for switching was lack of efficacy, an improvement in the PANSS total score of ≥20% occurred in 57.4% of patients. Noninferiority was confirmed for each subgroup of patients whose main reason for switching was something other than lack of efficacy. Paliperidone ER was generally well tolerated. Extrapyramidal symptoms as measured by total Extrapyramidal Symptom Rating Scale scores showed statistically significant and clinically relevant improvements at endpoint, the average weight decreased by 0.8±5.2 kg at endpoint, and a clinically relevant weight gain of ≥7% occurred in 8.0% of patients. Conclusion: Paliperidone ER flexibly-dosed over 6 months was well tolerated and associated with a meaningful clinical response in patients with nonacute schizophrenia who had previously been unsuccessfully treated with oral olanzapine. PMID:26813484

  20. A Flexible-Dose Study of Paliperidone ER in Patients With Nonacute Schizophrenia Previously Treated Unsuccessfully With Oral Olanzapine.

    Science.gov (United States)

    Kotler, Moshe; Dilbaz, Nesrin; Rosa, Fernanda; Paterakis, Periklis; Milanova, Vihra; Smulevich, Anatoly B; Lahaye, Marjolein; Schreiner, Andreas

    2016-01-01

    The goal of this study was to explore the tolerability, safety, and treatment response of switching from oral olanzapine to paliperidone extended release (ER). Adult patients with nonacute schizophrenia who had been treated unsuccessfully with oral olanzapine were switched to flexible doses of paliperidone ER (3 to 12 mg/d). The primary efficacy outcome was a ≥ 20% improvement in Positive and Negative Syndrome Scale (PANSS) total scores from baseline to endpoint for patients who switched medications because of lack of efficacy with olanzapine and noninferiority versus previous olanzapine treatment (mean endpoint change in PANSS total scores vs. baseline of ≤ 5 points) for patients who switched for reasons other than lack of efficacy. Safety and tolerability were assessed by monitoring adverse events, extrapyramidal symptoms, and weight change. Of 396 patients, 65.2% were men, mean age was 40.0 ± 12.0 years, and 75.5% had paranoid schizophrenia. Among the patients whose main reason for switching was lack of efficacy, an improvement in the PANSS total score of ≥ 20% occurred in 57.4% of patients. Noninferiority was confirmed for each subgroup of patients whose main reason for switching was something other than lack of efficacy. Paliperidone ER was generally well tolerated. Extrapyramidal symptoms as measured by total Extrapyramidal Symptom Rating Scale scores showed statistically significant and clinically relevant improvements at endpoint, the average weight decreased by 0.8 ± 5.2 kg at endpoint, and a clinically relevant weight gain of ≥ 7% occurred in 8.0% of patients. Paliperidone ER flexibly-dosed over 6 months was well tolerated and associated with a meaningful clinical response in patients with nonacute schizophrenia who had previously been unsuccessfully treated with oral olanzapine.

  1. Current status of regional hydrogeological studies and numerical simulations on geological disposal

    International Nuclear Information System (INIS)

    Nakao, Shinsuke; Kikuchi, Tsuneo; Ishido, Tsuneo

    2004-01-01

    Current status of regional hydrogeological studies on geological disposal including hydrogeological modeling using numerical simulators is reviewed in this report. A regional scale and boundary conditions of numerical models are summarized mainly from the results of the RHS (regional hydrogeological study) project conducted by Japan Nuclear Cycle Development Institute (JNC) in the Tono area. We also refer to the current conceptual modes of hydrology and numerical models of unsaturated zone flow at Yucca Mountain, Nevada, which is the arid site proposed for consideration as the United States' first underground high-level radioactive waste repository. Understanding behavior of a freshwater-saltwater transition zone seems to play a key role in the hydrogeological modeling in a coastal region. Technical features of a numerical simulator as a tool for geothermal reservoir modeling is also briefly described. (author)

  2. Structural mapping from MSS-LANDSAT imagery: A proposed methodology for international geological correlation studies

    Science.gov (United States)

    Dejesusparada, N. (Principal Investigator); Crepani, E.; Martini, P. R.

    1980-01-01

    A methodology is proposed for international geological correlation studies based on LANDSAT-MSS imagery, Bullard's model of continental fit and compatible structural trends between Northeast Brazil and the West African counterpart. Six extensive lineaments in the Brazilian study area are mapped and discussed according to their regional behavior and in relation to the adjacent continental margin. Among the first conclusions, correlations were found between the Sobral Pedro II Lineament and the megafaults that surround the West African craton; and the Pernambuco Lineament with the Ngaurandere Linemanet in Cameroon. Ongoing research to complete the methodological stages includes the mapping of the West African structural framework, reconstruction of the pre-drift puzzle, and an analysis of the counterpart correlations.

  3. Hydrological and geological preliminary studies in the scope of the RMB project

    International Nuclear Information System (INIS)

    Ferreira, Vinicius V.M.; Barreto, Alberto A.; Aleixo, Bruna L.

    2011-01-01

    The RMB - Brazilian Multipurpose Reactor is a project that will contribute decisively in order to develop the science and the technology of the country. However, the licensing process of this facility is not a simple task, since it involves nuclear and environmental questions. The utilization of geoprocessing tools became in the last years an important technique to aid the development of several studies, and will be necessary also in this project. The objective of this work is to present the first hydrological and geological geoprocessing studies done in order to support the future environmental licensing process of the facility. The results show that further efforts should be done since there is a lack of many data needed for the next steps. (author)

  4. Drone photogrammetry for geological research: field digital stratigraphic logs for turbiditic reservoir analog studies in Calabria, Southern Italy.

    Science.gov (United States)

    Guillois, Maxime; Brocheray, Sandra; Paron, Paolo

    2017-04-01

    Drone technology combined with new algorithms like Structure from Motion (SfM) has revived and expanded the uses of photogrammetry bringing new flexibility and the capacity to carry on close range photogrammetry to inaccessible areas. This characteristics are particularly appealing in field geology offering the option to reconstruct continuous digital outcrop models of vertical or difficult to reach outcrops. In this light we present the results of a digital outcrop modelling of a Miocene turbiditic system (mainly sandstone) in Calabria (Southern Italy) generated through field data collected by means of a light-weight commercial drone, a detailed geological field survey and cloud point photogrammetric analyses comparing different software for this purpose (Agisoft Photoscan, Drone deploy, Arc3D). The geological model has been used as an input for preliminary reservoir modelling. We generated digital geological sections (stratigraphic logs) of 1,200 m of sections using expert digital image and terrain model interprepation from the DTM generated with drone data, with the goal to reconstruct the real thickness of each layer. We then compared the results with previously created detailed field geological cross sections. The comparison between drone-derived sections and field-survey sections shows a global accuracy of the thickness ranging between 1% to 10%. Although this new methodology still has to be validated in other morpho-lithological context it already demonstrating its usefulness for preliminary geological outcrop investigation and modelling in remote areas. We also compared the different softwares used and we made recommendations for future deployment. This research has been made possible thanks to a collaboration between UNESCO-IHE, The Netherlands, and UniLaSalle Beauvais, France.

  5. Gas geochemistry of natural analogues for the studies of geological CO2 sequestration

    International Nuclear Information System (INIS)

    Voltattorni, N.; Sciarra, A.; Caramanna, G.; Cinti, D.; Pizzino, L.; Quattrocchi, F.

    2009-01-01

    Geological sequestration of anthropogenic CO 2 appears to be a promising method for reducing the amount of greenhouse gases released to the atmosphere. Geochemical modelling of the storage capacity for CO 2 in saline aquifers, sandstones and/or carbonates should be based on natural analogues both in situ and in the laboratory. The main focus of this paper has been to study natural gas emissions representing extremely attractive surrogates for the study and prediction of the possible consequences of leakage from geological sequestration sites of anthropogenic CO 2 (i.e., the return to surface, potentially causing localised environmental problems). These include a comparison among three different Italian case histories: (i) the Solfatara crater (Phlegraean Fields caldera, southern Italy) is an ancient Roman spa. The area is characterised by intense and diffuse hydrothermal activity, testified by hot acidic mud pools, thermal springs and a large fumarolic field. Soil gas flux measurements show that the entire area discharges between 1200 and 1500 tons of CO 2 per day; (ii) the Panarea Island (Aeolian Islands, southern Italy) where a huge submarine volcanic-hydrothermal gas burst occurred in November, 2002. The submarine gas emissions chemically modified seawater causing a strong modification of the marine ecosystem. All of the collected gases are CO 2 -dominant (maximum value: 98.43 vol.%); (iii) the Tor Caldara area (Central Italy), located in a peripheral sector of the quiescent Alban Hills volcano, along the faults of the Ardea Basin transfer structure. The area is characterised by huge CO 2 degassing both from water and soil. Although the above mentioned areas do not represent a storage scenario, these sites do provide many opportunities to study near-surface processes and to test monitoring methodologies.

  6. CO2-Brine Displacement in Geological CO2 Sequestration: Microfluidic Flow Model Study

    Science.gov (United States)

    Cao, S. C.; Jung, J.

    2014-12-01

    Geological CO2 sequestration is a promising method to reduce atmospheric CO2 and deep saline aquifers is one of the most important options due to their capacity for CO2 storage. Thus, a better understanding of two immiscible brine-CO2 mobility and its saturation, including invading patterns in deep saline aquifers as CO2 storage sites is required. Lenormand (1990) explored the invading patterns of two immiscible fluids in porous media with a transition region and three dominant regions: capillary fingering, viscous fingering, and stable displacement. These are determined by two main aspect ratios Nm and Nc through experimental studies using micromodel. Micromodel provides the opportunity to discover unrecognized processes, and test existing theories and assumptions in fluid flow through porous media. In this study, the micromodel was used to explore the effects of the scCO2 injecting velocity and ionic strength on invading patterns in geological CO2 sequestration. When scCO2 was injected into the micromodel that has already saturated with brine, the brine in the micromodel was displaced by injected scCO2. Continuous scCO2 injection into the micromodel leaded the scCO2 to pass through the micromodel. And the scCO2-brine displacement distribution in the micromodel remained constant during additional 100 PV scCO2 injection after injecting scCO2 passed through micromodel. When scCO2 passed through the porous media, the scCO2-brine displacement distribution represented the maximum displacement ratio. Results showed that scCO2-brine displacement ratios increased with: elevated pressures in the range of 3MPa~8MPa, decreased ionic strength from 5M to 1M NaCl, and increased scCO2 injecting velocity up to 40 μL/min. Also, Nm and Nc obtained in this study are located in transition region of the invading patterns suggested by Lenormand (1990).

  7. Effect of local geology on indoor radon levels: a case study

    Energy Technology Data Exchange (ETDEWEB)

    Hawthorne, A.R.; Gammage, R.B.; Dudney, C.S.

    1984-01-01

    This paper presents the results of radon monitoring in 40 East Tennessee homes that were a component of a larger study to evaluate indoor air quality. Measurements were conducted during two 3-month time periods with passive integrating track etch monitors in each of the forty homes. In a subset of homes, measurements were also conducted with a real-time monitor that provided readings on an hourly basis. The results of the monitoring indicate that about 30% of the homes had radon levels were associated with local variations in geology; most of the homes having higher levels were located on the porous dolomite ridge partially surrounding Oak Ridge, Tennessee. 7 references, 3 figures, 2 tables.

  8. Effect of local geology on indoor radon levels: a case study

    International Nuclear Information System (INIS)

    Hawthorne, A.R.; Gammage, R.B.; Dudney, C.S.

    1984-01-01

    This paper presents the results of radon monitoring in 40 East Tennessee homes that were a component of a larger study to evaluate indoor air quality. Measurements were conducted during two 3-month time periods with passive integrating track etch monitors in each of the forty homes. In a subset of homes, measurements were also conducted with a real-time monitor that provided readings on an hourly basis. The results of the monitoring indicate that about 30% of the homes had radon levels were associated with local variations in geology; most of the homes having higher levels were located on the porous dolomite ridge partially surrounding Oak Ridge, Tennessee. 7 references, 3 figures, 2 tables

  9. The use of lidar images in Costa Rica : case studies applied in geology, engineering, and archaeology

    International Nuclear Information System (INIS)

    Ruiz, Paulo; Garro, Jose F.; Soto, Gerardo J.

    2014-01-01

    A historical review is made about evolution of technology Lidar (Laser Imaging Detection and Ranging). The improvements of this technology and additions from other technologies are annotated in the last 15 years. The information of the aerial and terrestrial lidar operation, technical parameters for data acquisition and resolutions are presented. The results from four studies are presented in Costa Rica: 1) The discovery of pre-Columbian trails in the area of Volcan Arenal, 2) A case of geological mapping and discovery of new volcanic structures in the North area of the Volcan Poas, 3) The characterization of a landslide near Palmares that represents a hazard for the road network, 4) A detail survey of a pre-Columbian sphere. The results from new Lidar will become more frequent in the following years because its cost will be more affordable. The transference of data between institutions will generate new applications in different fields. (author) [es

  10. Geological and radiometric study of the anomaly ''San Martin'' municipality of Sierra Mojada, Coahuila

    International Nuclear Information System (INIS)

    Ibarra Mora, P.

    1975-01-01

    When it first became known that there were uranium ores at the mine known as San Martin (72 hectares, Mining Agency, Sabinas, Mexico), exploration work was started with the sinking of two wells at the sites of maximum radiometric intensity. A short while afterwards, however, this work was suspended. In 1974, the work required for evaluation of the locality was begun. Geological and radiometric studies carried out both at the surface and underground pointed to the conclusion that the San Martin anomaly, down to the depth explored (40 metres), is a stockwork-type deposit or a tabular seam of the fissure type. It was concluded that in view of the grades obtained (0.0227%U 3 O 6 ) down to 40 metres, the deposit cannot be considered of econimic importance at the present time. (author)

  11. Effect of local geology on indoor radon levels: a case study

    International Nuclear Information System (INIS)

    Hawthorne, A.R.; Gammage, R.B.; Dudney, C.S.

    1984-01-01

    This paper presents the results of radon monitoring in 40 East Tennessee homes that were a component of a larger study to evaluate indoor air quality. Measurements were conducted during two 3-month time periods with passive integrating track etch monitors in each of the forty homes. In a subset of homes, measurements were also conducted with a real-time monitor that provided readings on an hourly basis. The results of the monitoring indicate that about 30% of the homes had radon levels greater that 4 pCi/L in the living space. Homes with elevated radon levels were associated with local variations in geology; most of the homes having higher levels were located on the porous dolomite ridge partially surrounding Oad Ridge, Tennessee. (Author)

  12. Study of gases in six geologic faults in the Narino Department

    International Nuclear Information System (INIS)

    Moran Rodriguez, C; Chica Sanchez, A; Garzon Valencia, G

    2001-01-01

    Radon-222 and Carbon Dioxide emissions on the Manchabajoy, Pasto, Buesaco, Guaitara, Ancuya and Magdalena geological faults in the Narino Department were studied. As example of environmental influences like rainfall on the gas emissions in the San Francisco station, located in the Manchabajoy, Ancuya and Guaitara faults intersection was presented. Another environmental perturbations, like air temperature and atmospheric pressure no varies too much and minimum influence gas emissions from soils. In the first semester of the 2000, several radon anomalies in six stations of the volcanological and seismological observatory of Pasto were registered. After cited Radon anomalies inhabitants of Pasto city filled a seismic swarm in July months, and probably a correlation between radon anomalies and detected seismic signals have to be taken into account

  13. Study of gases in six geologic faults in the Department of Narino

    International Nuclear Information System (INIS)

    Moran Rodriguez, C; Chica Sanchez, A; Garzon Valencia, G

    2001-01-01

    Radon-222 and carbon dioxide emissions on the Manchabajoy, Pasto, Buesaco, Guaitara, Ancuya and Magdalena geological faults in the Narino Department were studied. As example of environmental influences like rainfall on the gas emissions in the San Francisco Station, located in the Manchabajoy, Ancuya and Guaitara faults intersection was presented. Another environmental perturbations, like air temperature and atmospheric pressure no varies too much and minimum influence gas emissions from soils. In the first semester of the 2000, several radon anomalies in six stations of the volcanological and seismological observatory of Pasto were registered. After cited radon anomalies a seismic swarm were filled by inhabitants of Pasto City in July months, and probably a correlation between radon anomalies and detected seismic signals have to be taken into account

  14. Preliminary geologic studies of Sierra El Aguajito (Baja California, Mexico): a resurgent-type caldera

    Science.gov (United States)

    Garduño-Monroy, V. H.; Vargas-Ledezma, H.; Campos-Enriquez, J. O.

    1993-12-01

    Geologic field studies conducted in the Quaternary volcanic field of Tres Virgenes (State of Baja California Sur, Mexico) revealed the existence of a resurgent caldera. The caldera's eruptive products, the Aguajito sequence, overlie the products of the nearby Reforma caldera (Reforma sequence) whose youngest products have already been dated as Quaternary. The rim of the Aguajito caldera is inferred by the existence of an arcuate alignment of rhyolitic domes. The mean diameter of this subcircular feature is 10 km. The volume of its mapped acidic products is a minimum of 10 km 3. Several horizons within the sequence contain shells. K/Ar dates of the ignimbrites and domes of El Aguajito formation confirm that the unit are Pleistocene. The detailed stratigraphy also shows the evolution of a marine regression partly related to the caldera.

  15. Geology of Mars

    International Nuclear Information System (INIS)

    Soderblom, L.A.

    1988-01-01

    The geology of Mars and the results of the Mariner 4, 6/7, and 9 missions and the Viking mission are reviewed. The Mars chronology and geologic modification are examined, including chronological models for the inactive planet, the active planet, and crater flux. The importance of surface materials is discussed and a multispectral map of Mars is presented. Suggestions are given for further studies of the geology of Mars using the Viking data. 5 references

  16. Studies of nuclear-waste migration in geologic media. Annual report, November 1976--October 1977

    International Nuclear Information System (INIS)

    Seitz, M.G.; Rickert, P.G.; Fried, S.M.; Friedman, A.M.; Steindler, M.J.

    1978-03-01

    The confinement of nuclear wastes in geologic formations is being considered as a method of permanently disposing of the waste. Laboratory experiments (column infiltration, static absorption, and batch partitioning experiments) were performed with nuclides of Cs, Pu, Np, and Am to examine the migratory characteristics of long-lived radionuclides that could be mobilized by groundwaters infiltrating a nuclear waste repository and the surrounding geologic body. In column infiltration experiments, the positions of peak concentrations of Cs in chalk or shale columns; Pu in limestone; Am in limestone, sandstone, or tuff; and Np in a limestone column did not move when the columns were infiltrated with water. However, fractions of each of the nuclides were seen downstream from the peaks, indicating that there was a large dispersion in the relative migration rates of each of the trace elements in the lithic materials studied. The results of static absorption experiments indicate that Pu and Am are strongly absorbed from solution by the common rocks studied and that their migration relative to ground-water flow is thereby retarded. In addition, the reaction rates of dissolved nuclides with rocks were found to vary considerably in different rock-element systems. Batch partitioning experiments were performed to test whether absorption processes are reversible. After granulated basalt and americium-bearing water were contacted in an absorption step, part of the water was replaced with water free of Am and the Am repartitioned between rock and solution. The distribution of Am after desorption was comparable to its distribution after absorption. In cntrast, when tablets of various rocks were allowed to dry between absorption and desorption tests, Pu and Am were not generally desorbed from the tablets. This suggests that reversible reactions of nuclides, between waters and rocks may be upset by treatments such as drying

  17. Marapi an active West-Central Sumatra Volcano: a geological and petrological study

    Science.gov (United States)

    Del Marmol, M.; Budianto, A.; Fournelle, J.; Jacobs, P.; Elburg, M. A.

    2010-12-01

    Marapi volcano (West - Central Sumatra), Sumatra’s most active volcano (not to be confused with Merapi on Java), located in a densely populated area and where more than 50 explosive eruptions have been recorded in the last 200 years has been studied in detail in the field to gain fundamental understanding of the volcano's activity in terms of its basic geology, petrology and geochemistry. Marapi is one of a few active volcanoes among many dormant volcanoes of this island. Large deposits of the nearby Maninjau caldera, dated 50 ka (n=3), associated with very silica-rich volcanic products is another reason for concern, since caldera formation is linked with severe explosive activity. Those deposits are found at the base of the volcano and largely in the deeply incised valley which follows the Sumatra fault extending parallel to the Sumatra volcanic front. A possible landslide parallel to the Sumatra fault is recognized on the LANDSAT image. Landslides on the external old external side have allowed the collection of the oldest part of the volcano as most of it is covered with a thick primary forest. These landslides occurring on old volcanic terrain are a threat to the surrounding population living nearby the rivers especially during the heavy rainy seasons. A 20 m high stratigraphic column has been studied, with the volcano’s explosive nature seen in the collected samples (i.e. bombs and pumices). A new sketch map of the area of the craters (6 over 2km) replaces the one made in 1921 at the Dutch colonial time. A geological and hazard map have been created showing the extension of the various deposits.

  18. Patterns and Determinants of Treatment Seeking among Previously Untreated Psychotic Patients in Aceh Province, Indonesia: A Qualitative Study

    Directory of Open Access Journals (Sweden)

    Marthoenis Marthoenis

    2016-01-01

    Full Text Available Immediate treatment of first-episode psychosis is essential in order to achieve a positive outcome. However, Indonesian psychiatric patients often delay accessing health services, the reason for which is not yet fully understood. The current study aimed to understand patterns of treatment seeking and to reveal determinants of the delay in accessing psychiatric care among first-time user psychotic patients. Qualitative interviews were conducted with sixteen family members who accompanied the patients to a psychiatric hospital. Many families expressed beliefs that mental illness appertains to village sickness and not hospital sickness; therefore, they usually take the patients to traditional or religious healers before taking them to a health professional. They also identified various factors that potentially delay accessing psychiatric treatment: low literacy and beliefs about the cause of the illness, stigmatisation, the role of extended family, financial problems, and long distance to the psychiatric hospital. On the other hand, the family mentioned various factors related to timely help seeking, including being a well-educated family, living closer to health facilities, previous experience of successful psychotic therapy, and having more positive symptoms of psychosis. The findings call for mental health awareness campaigns in the community.

  19. Pilot Study of an Individualised Early Postpartum Intervention to Increase Physical Activity in Women with Previous Gestational Diabetes

    Directory of Open Access Journals (Sweden)

    Harold David McIntyre

    2012-01-01

    Full Text Available Optimal strategies to prevent progression towards overt diabetes in women with recent gestational diabetes remain ill defined. We report a pilot study of a convenient, home based exercise program with telephone support, suited to the early post-partum period. Twenty eight women with recent gestational diabetes were enrolled at six weeks post-partum into a 12 week randomised controlled trial of Usual Care (n=13 versus Supported Care (individualised exercise program with regular telephone support; n=15. Baseline characteristics (Mean ± SD were: Age  33±4  years; Weight 80 ± 20 kg and Body Mass Index (BMI 30.0±9.7 kg/m2. The primary outcome, planned physical activity {Median (Range}, increased by 60 (0–540 mins/week in the SC group versus 0 (0–580 mins/week in the UC group (P=0.234. Walking was the predominant physical activity. Body weight, BMI, waist circumference, % body fat, fasting glucose and insulin did not change significantly over time in either group. This intervention designed to increase physical activity in post-partum women with previous gestational diabetes proved feasible. However, no measurable improvement in metabolic or biometric parameters was observed over a three month period.

  20. Prediction of hidden Au and Cu-Ni ores from depleted mines in Northwestern China: four case studies of integrated geological and geophysical investigations

    Science.gov (United States)

    Shen, Ping; Shen, Yuanchao; Liu, Tiebing; Li, Guangming; Zeng, Qingdong

    2008-07-01

    Integrated geological and geophysical investigations were carried out in 26 active mines in Northwestern China during the period 2001-2006 to explore for hidden extensions of known ore bodies and to search for new mineralization. This paper presents four case studies from northwest China: the Kuoerzhenkuoa volcanogenic hydrothermal gold deposit, the Nanjinshan breccia-associated gold deposit, the Duolanasayi deposit, associated with a ductile-shear zone, and the Hulu magmatic Cu-Ni sulfide deposit. In these studies, detailed mine-scale geological studies were carried out to determine the location and controls on ore formation. Based on these investigations and a review of previous exploration data, genetic models for the deposits were evaluated, and specific new targets were generated. These target areas were tested with surface geophysical surveys using the Stratagem EH4 system, a hybrid-source magnetotellurics (MT) method. Analysis of the data obtained in the surveys identified geophysical target anomalies that were subsequently drilled. Many of these test holes demonstrate the presence of Au and Cu-Ni mineralization. Evaluation of the geological models was crucial in developing conceptual targets as a basis for surface geophysical surveys. These models established the most likely target areas where Au and Cu-Ni mineralization could occur, but they did not define the limits or the geometries of the mineralized zones. Hybrid MT surveys played an important role in defining the location of buried mineralized systems and in testing the validity of the conceptual targets. The resistivity cross-sections obtained by imaging the MT data established the boundaries and geometries of the host rocks, including the distribution of lithology, structures, alteration, and mineralization. The four case studies in this paper show how this integrated geological and geophysical approach was used successfully to discover hidden mineral deposits.

  1. Transboundary study of the Milk River aquifer (Canada, USA): geological, conceptual and numerical models for the sound management of the regional groundwater resources

    Science.gov (United States)

    Pétré, Marie-Amélie; Rivera, Alfonso; Lefebvre, René

    2016-04-01

    The Milk River transboundary aquifer straddles southern Alberta (Canada) and northern Montana (United States), a semi-arid and water-short region. The extensive use of this regional sandstone aquifer over the 20th century has led to a major drop in water levels locally, and concerns about the durability of the resources have been raised since the mid-1950. Even though the Milk River Aquifer (MRA) has been studied for decades, most of the previous studies were limited by the international border, preventing a sound understanding of the aquifer dynamics. Yet, a complete portrait of the aquifer is required for proper management of this shared resource. The transboundary study of the MRA aims to overcome transboundary limitations by providing a comprehensive characterization of the groundwater resource at the aquifer scale, following a three-stage approach: 1) The development of a 3D unified geological model of the MRA (50,000 km2). The stratigraphic framework on both sides of the border was harmonized and various sources of geological data were unified to build the transboundary geological model. The delineation of the aquifer and the geometry and thicknesses of the geological units were defined continuously across the border. 2) Elaboration of a conceptual hydrogeological model by linking hydrogeological and geochemical data with the 3D unified geological model. This stage is based on a thorough literature review and focused complementary field work on both sides of the border. The conceptual model includes the determination of the groundwater flow pattern, the spatial distribution of hydraulic properties, a groundwater budget and the definition of the groundwater types. Isotopes (3H, 14C, 36Cl) were used to delineate the recharge area as well as the active and low-flow areas. 3) The building of a 3D numerical groundwater flow model of the MRA (26,000 km2). This model is a transposition of the geological and hydrogeological conceptual models. A pre

  2. Using a pregnancy decision support program for women choosing birth after a previous caesarean in Japan: A mixed methods study.

    Science.gov (United States)

    Torigoe, Ikuyo; Shorten, Allison

    2018-02-01

    Opportunities for women and providers to use decision aids and share decisions about birth after caesarean in practice are currently limited in Japan. This is despite known benefits of decision aids to support value-sensitive healthcare decisions. To explore Japanese women's decision making experiences using a decision aid program for birth choices after caesarean. A mixed methods study was conducted among 33 consenting pregnant women with previous caesarean in five obstetrics institutions located in the western part of Japan. Outcome measures included change in level of decisional conflict, change in knowledge, and preference for birth method. Semi-structured interviews examined women's decision making experiences, and qualitative data were analyzed using thematic analysis. The participants in the program experienced a statistically significant improvement in knowledge and reduction in decisional conflict about birth after caesarean. Four themes were identified in the qualitative data related to decision making: change in women's knowledge about birth choices, clarifying women's birth preference, feelings about shared decision making, and contrasting feelings after receiving information. This study confirmed potential benefits of using the decision aid program. However, uncertainty about mode of birth continued for some women immediately prior to the birth. This finding emphasized the need to identify additional ways to support women emotionally throughout the process of decision making about birth after caesarean. It was feasible to adapt the decision aid for use in clinical practice. Future research is necessary to examine its effectiveness when implemented in Japanese clinical settings. Copyright © 2017 Australian College of Midwives. Published by Elsevier Ltd. All rights reserved.

  3. Geological setting of silica in Dehnow-Abid region (Eshghabad northeast using fluid inclusions studies

    Directory of Open Access Journals (Sweden)

    Omid Yazdanpanah

    2017-02-01

    Full Text Available Introduction Dehnow-Abid area is a part of the geological map of Eshghabad with scale 1:100000 (Aghanabati, 1994 that is located about 20 kilometers northeast of Eshghabad and in the coordinates of 57° 6´ 0" to 57° 10´ 0" eastern longitude and 34° 28´ 0" to 34 21´ 0" northern latitude. The Dehnow-Abid area is located in Tabas block and east of central Iran structural zone. The small continent east central Iran (Takin, 1972 includes blocks: Loot, Tabas and Yazd that constitute Iran's eastern part (Davoudzadeh and Schmidt, 1982. In geology, we can acquire more information about temperature forming minerals and rocks, pressure, density of the fluid and the chemical composition of the ore bearing fluids by fluid inclusions studies. Properties as well as their role in our understanding of the sources and evolution of ore bearing hydrothermal fluids and genesis of mineral deposits are very important (Rodder, 1979. In this study, we tried to use both field and laboratory studies, including petrography and thermometry studies of fluid inclusions, environment formation of quartz in the specified Dehno-Abid. Materials and methods At first, in order to identify the area, the 1:100000 map of Eshghabad was used. Then, for a complete cognition of mentioned area, after a few field visits and sampling of outcrops of quartz, we prepared 16 double polishing sections from some crystalline and milky quartz. Then, 10 thin sections of sandstones of that area were prepared for identification the host rock. Microscopic examinations on fluid inclusions were done by a LEICA DMLSP polarizing light microscope. Fluid inclusion micro-thermometry studies were done by using a Linkam THM S600 heating and freezing stage and with a TMS94 controller. Also, a cooling LNP which is mounted on an Olympus BX-41 microscope in Laboratory Fluid inclusion of Earth Sciences, Damghan University was used. Discussion and results Lithology of the Dehnow-Abid area included dark shale

  4. Study on fine geological modelling of the fluvial sandstone reservoir in Daqing oilfield

    Energy Technology Data Exchange (ETDEWEB)

    Zhoa Han-Qing [Daqing Research Institute, Helongjiang (China)

    1997-08-01

    These paper aims at developing a method for fine reservoir description in maturing oilfields by using close spaced well logging data. The main productive reservoirs in Daqing oilfield is a set of large fluvial-deltaic deposits in the Songliao Lake Basin, characterized by multi-layers and serious heterogeneities. Various fluvial channel sandstone reservoirs cover a fairly important proportion of reserves. After a long period of water flooding, most of them have turned into high water cut layers, but there are considerable residual reserves within them, which are difficult to find and tap. Making fine reservoir description and developing sound a geological model is essential for tapping residual oil and enhancing oil recovery. The principal reason for relative lower precision of predicting model developed by using geostatistics is incomplete recognition of complex distribution of fluvial reservoirs and their internal architecture`s. Tasking advantage of limited outcrop data from other regions (suppose no outcrop data available in oilfield) can only provide the knowledge of subtle changing of reservoir parameters and internal architecture. For the specific geometry distribution and internal architecture of subsurface reservoirs (such as in produced regions) can be gained only from continuous infilling logging well data available from studied areas. For developing a geological model, we think the first important thing is to characterize sandbodies geometries and their general architecture`s, which are the framework of models, and then the slight changing of interwell parameters and internal architecture`s, which are the contents and cells of the model. An excellent model should possess both of them, but the geometry is the key to model, because it controls the contents and cells distribution within a model.

  5. A Study on Using Hands-On Science Inquiries to Promote the Geology Learning of Preservice Teachers

    Science.gov (United States)

    Lai, Ching-San

    2015-01-01

    This study aims to investigate the geology learning performance of preservice teachers. A total of 31 sophomores (including 11 preservice teachers) from an educational university in Taiwan participated in this study. The course arrangements include class teaching and hands-on science inquiry activities. The study searches both quantitative and…

  6. Discovery of previously undetected intellectual disability by psychological assessment: a study of consecutively referred child and adolescent psychiatric inpatients.

    Science.gov (United States)

    Pogge, David L; Stokes, John; Buccolo, Martin L; Pappalardo, Stephen; Harvey, Philip D

    2014-07-01

    Intellectual disability is associated with an increased risk of behavioral disturbances and also complicates their treatment. Despite increases in the sophistication of medical detection of early risk for intellectual disability, there is remarkably little data about the detection of intellectual disability in cases referred for psychiatric treatment. In this study, we used a 10-year sample of 23,629 consecutive child and adolescent admissions (ages between 6 and 17) to inpatient psychiatric treatment. Eleven percent (n=2621) of these cases were referred for psychological assessment and were examined with a general measure of intellectual functioning (i.e., WISC-IV). Of these cases, 16% had Full Scale IQs below 70. Of the cases whose therapists then referred them for formal assessment of their adaptive functioning (i.e., ABAS-II) 81% were found to have composite scores below 70 as well. Only one of the cases whose Full Scale IQ was less than 70 had a referral diagnosis of intellectual disability. Cases with previously undetected intellectual disability were found to be significantly more likely to have a diagnosis of a psychotic disorder and less likely to have a diagnosis of mood disorder than cases with IQs over 70. Disruptive behavior disorder diagnoses did not differ as a function of intellectual performance. These data suggest a high rate of undetected intellectual disability in cases with a psychiatric condition serious enough to require hospitalization and this raises the possibility that many such cases may be misdiagnosed, the basis of their problems may be misconceptualized, and they may be receiving treatments that do not take into account their intellectual level. Copyright © 2014 Elsevier Ltd. All rights reserved.

  7. Uranium series radioactive disequilibria study using gamma spectrometry with low energy and application to the dating in geology

    International Nuclear Information System (INIS)

    Khoukhi, T. El.

    1992-01-01

    In this work, the gamma spectrometry with low energy has been used with the help of Ge high purity planar detector, and the means and limits of this spectrometry in the applications to the dating in geology has been studied. A geological sample taken from the moroccan phosphatic deposit of Gantour, having a secondary mineralization wealth of uranium has principally been studied in application. In addition, physical models of uranium genesis have been elaborated in the course of this work in order to interpret the achieved results. 60 figs., 18 tabs., 53 refs. (F.M.)

  8. Using Significant Geologic Hazards and Disasters to Focus Geoethics Case Studies

    Science.gov (United States)

    Cronin, V. S.

    2015-12-01

    Ethics education since classical times has involved the consideration of stories, parables, myths, fables, allegories and histories. These are the ancient equivalents of case studies. Modern case studies are used in applied-ethics courses in law, engineering, business, and science. When used in a geoscience course, geoethical case studies can enrich a student's understanding of the relationships between issues of geoscience, engineering, sociology, business, public policy and law - all with an ethical dimension. Perhaps more importantly, real cases affected real people. Students develop a strong empathetic connection to the people involved, enhancing students' drive to understand the interconnected layers of the cases. Students might begin to appreciate that geoscientists can help to avoid or alleviate human suffering -- that their careers can have meaning and purpose beyond simply earning a paycheck. Geologic disasters in which losses could have been predicted, avoided or minimized are quite effective as cases. Coupling a "disaster" case with a comparable "hazard" case is particularly effective. For example, there are many places along the San Andreas Fault in California where [1] significant coseismic displacement has occurred during historical times, [2] structures that are still inhabited were built along or across active traces prior to the Alquist-Priolo Earthquake Fault Zoning Act in 1971, and [3] inhabited structures have been built legally since 1971 within a few tens of feet of active traces. The question students confront is whether society ought to allow habitable structures to be built very near to a major active fault. This topic allows students to work with issues of law, history, seismology, seismic site response, crustal deformation adjacent to active faults, building codes and, ultimately, ethics. Similar progressions can be developed for other major geologic hazards, both natural and man-made, such as floods, landslides, erosion along rivers and

  9. Geologic Time.

    Science.gov (United States)

    Newman, William L.

    One of a series of general interest publications on science topics, the booklet provides those interested in geologic time with an introduction to the subject. Separate sections discuss the relative time scale, major divisions in geologic time, index fossils used as guides for telling the age of rocks, the atomic scale, and the age of the earth.…

  10. Associations of obesity with newly diagnosed and previously known atopic diseases in Chinese adults: a case-control study

    OpenAIRE

    Xie, Biao; Wang, Zhiqiang; Wang, Yupeng; Liu, Meina; Wang, Yongchen

    2017-01-01

    To assess the associations of obesity with newly diagnosed and previously known atopic disorders in Chinese adults. 4,629 adults aged 18 years or older were recruited in Harbin, China. Among them, 1,114 were previously diagnosed atopic cases, 1,298 were newly diagnosed cases, and 2,217 non-atopic controls. Obesity and overweight are defined according to the criteria established by the Working Group on Obesity in China. The associations of obesity with known and newly diagnosed atopic disorder...

  11. The laboratories of geological studies; Les laboratoires d`etudes geologiques

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-01-01

    This educational document comprises 4 booklets in a folder devoted to the presentation of the ANDRA`s activities in geological research laboratories. The first booklet gives a presentation of the missions of the ANDRA (the French agency for the management of radioactive wastes) in the management of long life radioactive wastes. The second booklet describes the approach of waste disposal facilities implantation. The third booklet gives a brief presentation of the scientific program concerning the underground geologic laboratories. The last booklet is a compilation of questions and answers about long-life radioactive wastes, the research and works carried out in geologic laboratories, the public information and the local socio-economic impact, and the storage of radioactive wastes in deep geological formations. (J.S.)

  12. 2010 Oregon Department of Geology and Mineral Industries (DOGAMI) Lidar: Eagle Point Study Area

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Oregon Department of Geology & Mineral Industries (DOGAMI) contracted with Watershed Sciences, Inc. to collect high resolution topographic LiDAR data for...

  13. 2010 Oregon Department of Geology and Mineral Industries (DOGAMI) Lidar: Klamath Study Area

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Oregon Department of Geology & Mineral Industries (DOGAMI) contracted with Watershed Sciences, Inc. to collect high resolution topographic LiDAR data for...

  14. 2011 Oregon Department of Geology and Mineral Industries (DOGAMI) Lidar: Pine Creek Study Area

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Oregon Department of Geology & Mineral Industries (DOGAMI) contracted with Watershed Sciences, Inc. to collect high resolution topographic LiDAR data for...

  15. Geology of the seashore

    OpenAIRE

    Institute, Marine

    2013-01-01

    There are many different types of beaches around Ireland. By looking at the geology of the seashore, students can study its rocks, soil, and minerals and learn about its origins. The geology of the seashore also offers a natural environment for many species and plants to live.

  16. Laparoscopy After Previous Laparotomy

    Directory of Open Access Journals (Sweden)

    Zulfo Godinjak

    2006-11-01

    Full Text Available Following the abdominal surgery, extensive adhesions often occur and they can cause difficulties during laparoscopic operations. However, previous laparotomy is not considered to be a contraindication for laparoscopy. The aim of this study is to present that an insertion of Veres needle in the region of umbilicus is a safe method for creating a pneumoperitoneum for laparoscopic operations after previous laparotomy. In the last three years, we have performed 144 laparoscopic operations in patients that previously underwent one or two laparotomies. Pathology of digestive system, genital organs, Cesarean Section or abdominal war injuries were the most common causes of previouslaparotomy. During those operations or during entering into abdominal cavity we have not experienced any complications, while in 7 patients we performed conversion to laparotomy following the diagnostic laparoscopy. In all patients an insertion of Veres needle and trocar insertion in the umbilical region was performed, namely a technique of closed laparoscopy. Not even in one patient adhesions in the region of umbilicus were found, and no abdominal organs were injured.

  17. Micro-CT in situ study of carbonate rock microstructural evolution for geologic CO2 storage

    Science.gov (United States)

    Zheng, Y.; Yang, Y.; Rogowska, M.; Gundlach, C.

    2017-09-01

    To achieve the 2°C target made in the 2016 Paris Agreement, it is essential to reduce the emission of CO2 into the atmosphere. Carbon Capture and Storage (CCS) has been given increasing importance over the last decade. One of the suggested methods for CCS is to inject CO2 into geologic settings such as the carbonate reservoirs in the North Sea. The final aim of our project is to find out how to control the evolution of petrophysical parameters during CO2 injection using an optimal combination of flow rate, injection pressure and chemical composition of the influent. The first step to achieve this is to find a suitable condition to create a stable 3D space in carbonate rock by injecting liquid to prepare space for the later CO2 injection. Micro-CT imaging is a non-destructive 3D method that can be used to study the property changes of carbonate rocks during and after CO2 injection. The advance in lab source based micro-CT has made it capable of in situ experiments. We used a commercial bench top micro-CT (Zeiss Versa XRM410) to study the microstructure changes of chalk during liquid injection. Flexible temporal CT resolution is essential in this study because that the time scales of coupled physical and chemical processes can be very different. The results validated the feasibility of using a bench top CT system with a pressure cell to monitor the mesoscale multiphase interactions in chalk.

  18. Geology's Impact on Culture

    Science.gov (United States)

    Pizzorusso, Ann

    2017-04-01

    Most people consider geology boring, static and difficult. The fields of astronomy and physics have "rebranded" themselves with exciting programs formatted so as to be readily understandable to the general public. The same thing can be done for geology. My research on geology's influence on other disciplines has resulted in a book, Tweeting da Vinci, in which I was able to show how geology affected Italy's art, architecture, medicine, religion, literature, engineering and just about everything else. The reaction to the book and my lectures by both students and the general public has been very positive, including four gold medals, with reviews and comments indicating that they never knew geology could be so exciting. The book is very user friendly, packed with facts, full-color photos, paintings, sketches and illustrations. Complex aspects of geology are presented in an easily understandable style. Widely diverse topics—such as gemology, folk remedies, grottoes, painting, literature, physics and religion—are stitched together using geology as a thread. Quoting everyone from Pliny the Elder to NASA physicist Friedemann Freund, the work is solidly backed scholarship that reads as easily as a summer novel. The book can be used in classes such as physics, chemistry, literature, art history, medicine, Classical Studies, Latin, Greek and Italian. By incorporating a "geologic perspective" in these courses, it can be perceived as a more "all encompassing" discipline and encourage more students to study it. The lectures I have given on college campuses have resulted in students seeing their own majors from a different perspective and some have even signed up for introductory geology courses. One college organized summer course to the Bay of Naples based on the book. We followed the geology as well as the culture of the area and the students were profoundly moved. To encourage dialog, the book is linked to Facebook, Twitter and Instagram. This has enabled followers from

  19. Associations of obesity with newly diagnosed and previously known atopic diseases in Chinese adults: a case-control study.

    Science.gov (United States)

    Xie, Biao; Wang, Zhiqiang; Wang, Yupeng; Liu, Meina; Wang, Yongchen

    2017-03-02

    To assess the associations of obesity with newly diagnosed and previously known atopic disorders in Chinese adults. 4,629 adults aged 18 years or older were recruited in Harbin, China. Among them, 1,114 were previously diagnosed atopic cases, 1,298 were newly diagnosed cases, and 2,217 non-atopic controls. Obesity and overweight are defined according to the criteria established by the Working Group on Obesity in China. The associations of obesity with known and newly diagnosed atopic disorders were assessed using logistic regressions. Obesity was significantly associated with known atopic disorders (adjusted OR = 2.41 (95% CI: 1.81, 3.22)). The association of obesity with newly diagnosed atopic cases was not as strong as that with known cases, and was not statistically significant (adjusted OR = 1.27 (95% CI: 0.94, 1.72)). The similar pattern was observed in different allergic diseases, gender and age stratifications. The association between overweight and atopic diseases were not significant. Obesity is strongly associated with previously diagnosed atopic cases but not so with newly diagnosed atopic cases in Chinese adults. It is likely that people with atopic disorders have a higher risk of developing obesity. Our findings are important for the management of atopic disorders and chronic disease prevention among atopic disease patients.

  20. Prototype of Web-based Geological Data Sharing System using Free and Open Source Software

    Science.gov (United States)

    Nonogaki, S.; Masumoto, S.; Nemoto, T.

    2017-12-01

    Two-dimensional (2D) geological data, such as geological maps and geological cross-sections, have been shared to the public on the Web, due to its importance in understanding subsurface geological conditions. However, ordinary people cannot figure out subsurface geological conditions only from these 2D data. The purpose of this study is to share various types of geological data to the public in easy-to-understand style on the Web. For this purpose, we developed a prototype of web-based geological data sharing system using free and open source software. As a result, the developed system allows the users (1) to map locations of borehole logs with a geological map, (2) to search database for borehole logs by keywords, (3) to browse a surface-based geological model within arbitrary range, and (4) to generate a geological cross-section along arbitrary lines. The geological map and surface-based geological model have been constructed based on borehole logs beforehand. The geological cross-section can be generated from the surface-based geological model on-demand. In this system, all functions can be performed through a Web browser. In addition, a distribution of borehole logs and the surface-based geological model can be visualized in three-dimension (3D). The 3D visualization of geological data on the Web assists users in understanding subsurface geological conditions quickly and correctly with or without previous knowledge of geology. In conclusion, the developed system contributes to create better environments for promoting utilization of geological data. This work was supported by JSPS KAKENHI Grant Number JP16K21677.

  1. Radioimmunotherapy with Y-90-epratuzumab in patients with previously treated B-cell lymphoma. A fractionated dose-escalation study

    International Nuclear Information System (INIS)

    Linden, O.; Cavallin-Stahl, E.; Tennvall, J.; Hindorf, C.; Olsson, T.; Strand, S.E.; Stenberg, L.; Wingardh, K.

    2002-01-01

    Aim: Fractionated RIT may improve outcome by decreasing heterogeneity in absorbed dose and by increasing therapeutic window. The humanised anti-CD22 antibody, Epratuzumab, (Immunomedics, Inc., Morris Plains, NJ) can be given repeatedly with minimal risk of neutralising Ab (HAHA), making fractionated treatment with 90 Y-labelled epratuzumab possible. Materials and Methods: Patients with previously treated B-cell lymphoma received increasing number (2-4) of weekly infusions of 90 Y-epratuzumab. Patients received either 185 MBq/m 2 per infusion (group A), or, if they had a history of high-dose chemotherapy with stem-cell rescue, 92.5 MBq/m 2 per infusion (group B). The first infusion included 150 MBq of 111 Indium for scintigraphic verification of tumour targeting and dosimetry. 1.5 mg/kg epratuzumab was administered with each infusion. The treatment could be repeated once after 3 m. Results: Of 23 patients, 16 in group A and 6 in group B were evaluable for response. The RR in group A was 62% objective response (OR) and 25% CR/CRu. One patient in group B showed OR. OR was seen in aggressive and indolent lymphoma. Response was also long-lasting and event-free survival of patients showing CR/CRu was 14 to 25+ months. In group A all seven patient, receiving three infusions, showed less than grade 3 platelet and neutrophil toxicity, except for two patients suffering grade 3 neutropenia. Of five patients with 4 weekly infusions there were two patients with dose-limiting haematological toxicity (DLT), both recently treated with high dose cytosar before RIT. With criteria used the maximal tolerated dose was three infusions 185 MBq/m 2 . In group B no patient suffered DLT and one patient exhibited OR. Seven patients were retreated after 3 months with minor toxicity, but improvement in OR in two cases. No patient has developed HAHA. CD22 expression on tumour cells, as assessed by flow cytometry, is available in 18 of 22 patients. In group A, seven of eight patients with

  2. Pilot Study Using the Augmented Reality Sandbox to Teach Topographic Maps and Surficial Processes in Introductory Geology Labs

    Science.gov (United States)

    Woods, Terri L.; Reed, Sarah; Hsi, Sherry; Woods, John A.; Woods, Michael R.

    2016-01-01

    Spatial thinking is often challenging for introductory geology students. A pilot study using the Augmented Reality sandbox (AR sandbox) suggests it can be a powerful tool for bridging the gap between two-dimensional (2D) representations and real landscapes, as well as enhancing the spatial thinking and modeling abilities of students. The AR…

  3. Ion beam studies in the field of arts, archaeology and geology

    International Nuclear Information System (INIS)

    Elekes, Z.; Uzonyi, I.; Rajta, I.; Kiss, A.Z.; Gratuze, B.; Bugoi, R.; Constantinescu, B.; Sasianu, A.; Torbagyi, M.

    2000-01-01

    Complete text of publication follows. Obsidian [1]. The natural volcanic glass material means a great interest both in archaeometry and in geology. It was important trade item for prehistoric people as a raw material of many kind of artefact. From the geological point of view different type of obsidian melts are sensitive geochemical indictors for Earth processes. The accurate determination of elemental constituents of obsidians in both research fields is important. Based on the light element concentration data measured by Proton Induced Gamma-Ray-Emission (PIGE) method a distinction among samples resulted via various magmatic processes with diverse provenances is achieved. This was made possible by exploiting the excellent characteristics of our Clover-Ge-BGO detector system [2]. Using this instrument the determination of the concentration of lithium, an important trace element, became available. A comparison with the analysis of heavier elements carried out by Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry (LA-ICP-MS) technique is done. Dyrrhachium Silver Coins [3]. Analytical characterization of ancient silver coins (drachmas) issued by the Greek city Dyrrhachium 68-43 years BC was carried out by micro-PIXE method. Out of a 153 pieces Dyrrhachium drachma collection of the Coin Cabinet of the Hungarian National Museum 27 ones were analysed including four ancient imitations. The aim of this investigation was to involve the Hungarian artefacts into a comprehensive and systematic study of the coin-hoards discovered in the neighbourhood of Hungary (e.g. in Romania) in the framework of an international collaboration (COST G1). For the Hungarian and Romanian coins the same extent of degradation of the fineness of silver was observed (Ag = 92%) comparing to the ones minted in the second century BC. Sn proved to be a characteristic element for imitations (Sn = 1%). Another new result is that iron x-ray peaks are localized into <20 μm regions, i.e. iron is

  4. A Geological and Geophysical Study of the Geothermal Energy Potential of Pilgrim Springs, Alaska

    Energy Technology Data Exchange (ETDEWEB)

    Turner, Donald L.; Forbes, Robert B. [eds.

    1980-01-01

    The Pilgrim Springs geothermal area, located about 75 km north of Nome, was the subject of an intensive, reconnaissance-level geophysical and geological study during a 90-day period in the summer of 1979. The thermal springs are located in a northeast-oriented, oval area of thawed ground approximately 1.5 km{sup 2} in size, bordered on the north by the Pilgrim River. A second, much smaller, thermal anomaly was discovered about 3 km northeast of the main thawed area. Continuous permafrost in the surrounding region is on the order of 100 m thick. Present surface thermal spring discharge is {approx} 4.2 x 10{sup -3} m{sup 3} s{sup -1} (67 gallons/minute) of alkali-chloride-type water at a temperature of 81 C. The reason for its high salinity is not yet understood because of conflicting evidence for seawater vs. other possible water sources. Preliminary Na-K-Ca geothermometry suggests deep reservoir temperatures approaching 150 C, but interpretation of these results is difficult because of their dependence on an unknown water mixing history. Based on these estimates, and present surface and drill hole water temperatures, Pilgrim Springs would be classified as an intermediate-temperature, liquid-dominated geothermal system.

  5. Outlier detection by robust Mahalanobis distance in geological data obtained by INAA to provenance studies

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Jose O. dos, E-mail: osmansantos@ig.com.br [Instituto Federal de Educacao, Ciencia e Tecnologia de Sergipe (IFS), Lagarto, SE (Brazil); Munita, Casimiro S., E-mail: camunita@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Soares, Emilio A.A., E-mail: easoares@ufan.edu.br [Universidade Federal do Amazonas (UFAM), Manaus, AM (Brazil). Dept. de Geociencias

    2013-07-01

    The detection of outlier in geochemical studies is one of the main difficulties in the interpretation of dataset because they can disturb the statistical method. The search for outliers in geochemical studies is usually based in the Mahalanobis distance (MD), since points in multivariate space that are a distance larger the some predetermined values from center of the data are considered outliers. However, the MD is very sensitive to the presence of discrepant samples. Many robust estimators for location and covariance have been introduced in the literature, such as Minimum Covariance Determinant (MCD) estimator. When MCD estimators are used to calculate the MD leads to the so-called Robust Mahalanobis Distance (RD). In this context, in this work RD was used to detect outliers in geological study of samples collected from confluence of Negro and Solimoes rivers. The purpose of this study was to study the contributions of the sediments deposited by the Solimoes and Negro rivers in the filling of the tectonic depressions at Parana do Ariau. For that 113 samples were analyzed by Instrumental Neutron Activation Analysis (INAA) in which were determined the concentration of As, Ba, Ce, Co, Cr, Cs, Eu, Fe, Hf, K, La, Lu, Na, Nd, Rb, Sb, Sc, Sm, U, Yb, Ta, Tb, Th and Zn. In the dataset was possible to construct the ellipse corresponding to robust Mahalanobis distance for each group of samples. The samples found outside of the tolerance ellipse were considered an outlier. The results showed that Robust Mahalanobis Distance was more appropriate for the identification of the outliers, once it is a more restrictive method. (author)

  6. Outlier detection by robust Mahalanobis distance in geological data obtained by INAA to provenance studies

    International Nuclear Information System (INIS)

    Santos, Jose O. dos; Munita, Casimiro S.; Soares, Emilio A.A.

    2013-01-01

    The detection of outlier in geochemical studies is one of the main difficulties in the interpretation of dataset because they can disturb the statistical method. The search for outliers in geochemical studies is usually based in the Mahalanobis distance (MD), since points in multivariate space that are a distance larger the some predetermined values from center of the data are considered outliers. However, the MD is very sensitive to the presence of discrepant samples. Many robust estimators for location and covariance have been introduced in the literature, such as Minimum Covariance Determinant (MCD) estimator. When MCD estimators are used to calculate the MD leads to the so-called Robust Mahalanobis Distance (RD). In this context, in this work RD was used to detect outliers in geological study of samples collected from confluence of Negro and Solimoes rivers. The purpose of this study was to study the contributions of the sediments deposited by the Solimoes and Negro rivers in the filling of the tectonic depressions at Parana do Ariau. For that 113 samples were analyzed by Instrumental Neutron Activation Analysis (INAA) in which were determined the concentration of As, Ba, Ce, Co, Cr, Cs, Eu, Fe, Hf, K, La, Lu, Na, Nd, Rb, Sb, Sc, Sm, U, Yb, Ta, Tb, Th and Zn. In the dataset was possible to construct the ellipse corresponding to robust Mahalanobis distance for each group of samples. The samples found outside of the tolerance ellipse were considered an outlier. The results showed that Robust Mahalanobis Distance was more appropriate for the identification of the outliers, once it is a more restrictive method. (author)

  7. Gulf Coast Salt Domes geologic Area Characterization Report, East Texas Study Area. Volume II. Technical report

    International Nuclear Information System (INIS)

    1982-07-01

    The East Texas Area Characterization Report (ACR) is a compilation of data gathered during the Area Characterization phase of the Department of Energy's National Waste Terminal Storage program in salt. The characterization of Gulf Coast Salt Domes as a potential site for storage of nuclear waste is an ongoing process. This report summarizes investigations covering an area of approximately 2590 km 2 (1000 mi 2 ). Data on Oakwood, Keechi, and Palestine Domes are given. Subsequent phases of the program will focus on smaller land areas and fewer specific salt domes, with progressively more detailed investigations, possibly culminating with a license application to the Nuclear Regulatory Commission. The data in this report are a result of drilling and sampling, geophysical and geologic field work, and intensive literature review. The ACR contains text discussing data usage, interpretations, results and conclusions based on available geologic and hydrologic data, and figures including diagrams showing data point locations, geologic and hydrologic maps, geologic cross sections, and other geologic and hydrologic information. An appendix contains raw data gathered during this phase of the project and used in the preparation of these reports

  8. The growth of the continent through geological time studied by Nd isotope analysis of shales

    International Nuclear Information System (INIS)

    Allegre, C.J.; Rousseau, D.; Paris-7 Univ., 75

    1984-01-01

    We determined the Nd isotopic composition and the Sm/Nd ratios in a series of Australian shales ranging from 0.2 Gy to 3.3 Gy. The first result of this study is the constancy of the Sm/Nd ratio in these shales, as in granitoids. Secondly, the initial ( 143 Nd/ 144 Nd) ratio gives a regular curve decreasing through geological time. Both results confirm that shales are representative samples of the continental crust, when insoluble elements, like REE, are studied. We calculated their Nd model ages of crustal differentiation. The model ages regularly decrease with the stratigraphic ages and after 2 Gy, the curve flattens and tends to an asymptotic value at around 1.8 Gy. The significance of the shales is that they represent a mixture of continental materials and we consider the model age of such a mixture directly linked with the mean age of the continental portion feeding the sedimentary basin. From these results, we deduce a quantitative model of the growth curve of the continental source of the shales taking into account the effects of erosion which selectively sample recent mountains relative to shield areas. We propose that the results obtained here are representative of the whole Gondwana continent. Having studied the case of the Australian shales, we try to extend our study. First we applied our quantitative approach to the recent results obtained by O'Nions et al. on North Atlantic provinces. The continental growth curves obtained by our inversion procedure are quite distinct from the Australian shales showing the regional character of shales. (orig./WB)

  9. Bibliography of geologic studies: Columbia Plateau (Columbia River Basalt) and adjacent areas in Idaho

    International Nuclear Information System (INIS)

    Strowd, W.

    1978-11-01

    The objective of this compilation is to present a comprehensive listing of published, unpublished, and open-file references pertaining to the geology of the Columbia Plateau and adjacent areas in the State of Idaho. The bibliography was compiled in support of Rockwell's Basalt Waste Isolation Program that is evaluating the feasibility of nuclear waste storage in the Columbia River Basalt Group. The emphasis is on stratigraphy, structural geology, seismicity, and tectonics, although the nature of Columbia River Basalt distribution in Idaho has necessitated the inclusion of a sizeable collection of references on geology marginal to the Columbia Plateau and associated mineral resources. The bibliography is divided into two major sections, the alphabetical listing of all references and the subject index. The subject index is divided into 19 categories to facilitate locating a specific reference in the user's field of interest

  10. Capability Study For Using the Impulse Graphite Reactor For Activation Analysis of Geological Materials

    International Nuclear Information System (INIS)

    Azarov, V.A.; Silaev, M.E.

    1998-01-01

    The IGR reactor facility available in the Institute of Atomic Energy NNC RK is mainly used for testing the going and newly developed fuel compositions and reactor materials. In connection with a decrease of the demand in investigations like that there was considered the capability to use the reactor for solving another research and, particularly, applied problems. A mineral exploration is one of the urgent objectives in the Republic of Kazakstan, and in Semipalatinsk region in particular. To perform the exploration like that it's required, in addition to rough field investigations, the methods of analysis for element composition of geological materials, the difference of which is in their effectiveness, quality and low first cost. Activation methods of analysis allow to provide with a high analysis quality and effectiveness. Therefore, there was proposed to study the capability to use the IGR reactor for the activation analysis of geological materials. To solve this goal the following activity in three basic trends is required: 1. To create the needed theoretical and, on its basis, the methodical base for performing the analytical activity; 2. To create the experimental and technical and organizational infrastructure for the investigations, providing with a high productivity and low prime cost of work; 3. To conduct works on marketing and to use the going methodical and technical base on the market of services. Major objectives for the creation of the theoretical and methodical base for analysis are: a) the study of neutron and physical IGR reactor characteristics under various operation modes; b) the study of the radiation effect on the results of activation analysis; c) the simulation of the temperature mode for irradiation of samples in the reactor and experimental model survey; d) the study of the capability to use non-traditional elements and materials as neutron reactor flux monitors; e) the development of the technique for the experimental and computational

  11. Geological and Geophysical Study of the Hidalgo´s Scenic View South Hillside in Ciudad Juarez, Chihuahua

    Directory of Open Access Journals (Sweden)

    Dena-Ornelas O.S.

    2011-10-01

    Full Text Available Geologic risks are associated to the different processes inherited by the dynamic condition of the natural environment. Often, these processes have reached a natural state of equilibrium or stability. Nevertheless, in some instances human activity interferes with the natural order, modifying the existing equilibrium or balance state. Such is the example of some geologic rock outcrops, originally generated under pressure and temperature conditions, different from the ones found at the surface of the earth. These outcrops, when subjected to surface atmospheric conditions experience a sudden release of large forces associated to the potential energy accumulated over long periods of time (thousands to millions of years. The goal of this study is to focus on the anthropogenic disequilibrium induced over a segment of the Sierra de Juarez, consequence of the removal of large rock masses in the construction of a scenic point (Mirador Hidalgo and a traversing highway (Camino Real. The applied methodology consisted in the integration through a Geographic Information System (GIS of high-resolution topographic maps, terrain analysis, geologic mapping, electric resistivity tomography and time domain electromagnetic soundings as a mean to evaluate the potential hazard that the Mirador Hidalgo represents in terms of an arbitrary Geologic Susceptibility Index (GSI. Based on the obtained results, a series of immediate actions are proposed, which are to be considered in order to avoid continuing damage to the highway infrastructure as well as the potential loss of human lives.

  12. Evaluation of a rapid dipstick (Crystal VC for the diagnosis of cholera in Zanzibar and a comparison with previous studies.

    Directory of Open Access Journals (Sweden)

    Benedikt Ley

    Full Text Available The gold standard for the diagnosis of cholera is stool culture, but this requires laboratory facilities and takes at least 24 hours. A rapid diagnostic test (RDT that can be used by minimally trained staff at treatment centers could potentially improve the reporting and management of cholera outbreaks.We evaluated the Crystal VC™ RDT under field conditions in Zanzibar in 2009. Patients presenting to treatment centers with watery diarrhea provided a stool sample for rapid diagnostic testing. Results were compared to stool culture performed in a reference laboratory. We assessed the overall performance of the RDT and evaluated whether previous intake of antibiotics, intravenous fluids, location of testing, and skill level of the technician affected the RDT results.We included stool samples from 624 patients. Compared to culture, the overall sensitivity of the RDT was 93.1% (95%CI: 88.7 to 96.2%, specificity was 49.2% (95%CI: 44.3 to 54.1%, the positive predictive value was 47.0% (95%CI: 42.1 to 52.0% and the negative predictive value was 93.6% (95%CI: 89.6 to 96.5%. The overall false positivity rate was 50.8% (213/419; fieldworkers frequently misread very faint test lines as positive.The observed sensitivity of the Crystal VC RDT evaluated was similar compared to earlier versions, while specificity was poorer. The current version of the RDT could potentially be used as a screening tool in the field. Because of the high proportion of false positive results when field workers test stool specimens, positive results will need to be confirmed with stool culture.

  13. 2009 - 2010 Oregon Department of Geology and Mineral Industries (DOGAMI) Lidar: Deschutes Study Area

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Oregon Department of Geology June 14, 2010 30,161 31,969 10 Oct 12 - 17, 2009; May 29 - June 17, 2010 48,746 50,833 11 Oct 16 - Nov 5, 2009; May 28 - July 3,...

  14. Uncertainty studies and risk assessment for CO2 storage in geological formations

    International Nuclear Information System (INIS)

    Walter, Lena Sophie

    2013-01-01

    Carbon capture and storage (CCS) in deep geological formations is one possible option to mitigate the greenhouse gas effect by reducing CO 2 emissions into the atmosphere. The assessment of the risks related to CO 2 storage is an important task. Events such as CO 2 leakage and brine displacement could result in hazards for human health and the environment. In this thesis, a systematic and comprehensive risk assessment concept is presented to investigate various levels of uncertainties and to assess risks using numerical simulations. Depending on the risk and the processes, which should be assessed, very complex models, large model domains, large time scales, and many simulations runs for estimating probabilities are required. To reduce the resulting high computational costs, a model reduction technique (the arbitrary polynomial chaos expansion) and a method for model coupling in space are applied. The different levels of uncertainties are: statistical uncertainty in parameter distributions, scenario uncertainty, e.g. different geological features, and recognized ignorance due to assumptions in the conceptual model set-up. Recognized ignorance and scenario uncertainty are investigated by simulating well defined model set-ups and scenarios. According to damage values, which are defined as a model output, the set-ups and scenarios can be compared and ranked. For statistical uncertainty probabilities can be determined by running Monte Carlo simulations with the reduced model. The results are presented in various ways: e.g., mean damage, probability density function, cumulative distribution function, or an overall risk value by multiplying the damage with the probability. If the model output (damage) cannot be compared to provided criteria (e.g. water quality criteria), analytical approximations are presented to translate the damage into comparable values. The overall concept is applied for the risks related to brine displacement and infiltration into drinking water

  15. Recovery of total Hg from geological matrices: a methodological intercomparison study (W6)

    International Nuclear Information System (INIS)

    Bloom, N.S.; Vondergeest, E.J.; Preus, E.M.; Horvat, M.; Prosenc, N.; Kingston, S.; Apte, S.; Pobbs, C.

    2002-01-01

    Full text: Aqua regia is commonly used for the extraction of Hg from soils prior to cold vapor spectrometry, but mass balance studies suggested it is not sufficiently robust to recover all Hg from more recalcitrant materials such as crystalline ores. As a result, an intercomparison exercise was undertaken between the following methods: (a) aqua regia digestion (EPA 7471) followed by SnCl 2 reduction, gold trapping and CVAFS detection, (b) Teflon bomb digestion at 110 o C with a 10:5:2 HNO 3 + HF + HCl mixture followed by SnCl 2 reduction, gold trapping and CVAFS, (c) 800 o C pyrolysis with gold trapping and CVAAS detection (EPA 7473), and (d) NAA followed by radiochemical separations using oxidative combustion and gold trapping. All methods gave quantitative recoveries from soil and sediment CRMs, but only the HF/HCI/HNO 3 digestion gave quantitative recoveries in all media. Pyrolysis resulted in approximately 88 ± 10 % recovery, while aqua regia digestion resulted in only about 61 ± 24 % recovery in bauxite ores and residues. RNAA generally gave the best agreement with the HF based digestion, although in a significant number of samples, particularly bauxite ores, recoveries were as low as 50 %. Based on these findings, we recommend that bomb digestions which include the use HF be applied to the analysis of Hg in geological solids, unless the matrix is documented to be fully extractable by a less rigorous procedure. We suggest a reference value for Hg in bauxite reference material (NIST-600) of 79.0 ± 2.0 ng/g, based on the pooled results of three laboratories. (author)

  16. Study on Regional Geology and Uranium Mineralization of Schwaner Mountains West and Central Kalimantan

    International Nuclear Information System (INIS)

    Soepradto-Tjokrokardono; Djoko-Soetarno; MS; Liliek-Subiantoro; Retno-Witjahyati

    2004-01-01

    Uranium occurrences indication in Kalimantan has been discovered at metamorphic and granites rocks of Schwaner Mountains as the radioactivity and geochemical anomalies. A regional geology of Schwaner Mountains show a watershed of West and East Kalimantan consist of Pinoh metamorphic rocks that was intruded by tonalitic and granitic batholite. The goal of this study is to observe the mechanism of the Uranium occurrences related to the regional tectonic, metamorphic rocks, tonalite and granitic batholite. Permokarbonaferrous metamorphic rocks as the big masses of roof pendant within tonalite mass. The metamorphic rocks originally as the big masses of roof pendant within tonalite mass. The metamorphic rocks originally derived from sedimentary process that produce a high content of uranium as well as a fine grained volcanic material. This uranium is deposited within neritic facies. Those sediments have been metamorphosed by low grade Abukuma regional metamorphism at the condition about 540 o C and 2000 bar. In early Cretaceous Tonalite of Sep auk intruded the rock and both metamorphics and tonalites. Those rocks were intruded by Late Cretaceous alkalin granite of Sukadana. Those crystalline rocks overlaid by an unconformity-related Kampari and Tebidah Formations that including within Melawi Group of Tertiary age. Uranium mineralization as the centimetric-metric veins related to tectonic N 100 o -110 o E and N 50 o E lineaments. Uranium was interpreted as a volcanic sedimentary origin, than it re mobilized by low grade regional metamorphism process. This enuchment process was carried out by fluor, boron and other metalliferous mineral within hydrothermal solutions of Sukadana granite. (author)

  17. Preliminary results of geologic and remote sensing studies of Rima Mozart

    International Nuclear Information System (INIS)

    Coombs, C.R.; Hawke, B.R.

    1987-01-01

    In order to better understand the processes responsible for the formation of lunar sinuous rilles, a study of Rima Mozart was conducted using a variety of geologic, photographic, and remote sensing data. The apparent source of this rille is located in a highlands unit of known composition and it is hypothesized that thermal and mechanical erosion played an important role in the formation of Rima Mozart. Excellent photographic, topographic, multispectral, and radar data exist for this rille. The preliminary results of an analysis of this data are presented. Photographic data indicates the presence of two volcanic source vents for Rima Mozart: Kathleen and Ann. It is suggested that Rima Mozart, like many other lunar sinuous rilles, was most likely formed by a combination of events. Rima Mozart does follow a pre-existing, dominant NW/SE structural trend suggesting the influence of structural features on the rille, however, the tectonic influence is not the sole source for the formation of the rille, as suggested by the presence of the two source vents and the spatter around Ann. It is suggested that the rille formation began with an explosive eruption at Kathleen which later calmed down to a pulsating, high volume, low-viscosity lava flow. The rapid effusion rate of the magma as well as its high temperature and turbid nature helped carve the sinuous rille into the fractured and structurally weak Apennine Bench Formation underneath. Similar eruptions and subsequent flows were also created at Ann and joined to the main channel by a NE-trending secondary rille

  18. Preliminary results of geologic and remote sensing studies of Rima Mozart

    Science.gov (United States)

    Coombs, C. R.; Hawke, B. R.

    1987-01-01

    In order to better understand the processes responsible for the formation of lunar sinuous rilles, a study of Rima Mozart was conducted using a variety of geologic, photographic, and remote sensing data. The apparent source of this rille is located in a highlands unit of known composition and it is hypothesized that thermal and mechanical erosion played an important role in the formation of Rima Mozart. Excellent photographic, topographic, multispectral, and radar data exist for this rille. The preliminary results of an analysis of this data are presented. Photographic data indicates the presence of two volcanic source vents for Rima Mozart: Kathleen and Ann. It is suggested that Rima Mozart, like many other lunar sinuous rilles, was most likely formed by a combination of events. Rima Mozart does follow a pre-existing, dominant NW/SE structural trend suggesting the influence of structural features on the rille, however, the tectonic influence is not the sole source for the formation of the rille, as suggested by the presence of the two source vents and the spatter around Ann. It is suggested that the rille formation began with an explosive eruption at Kathleen which later calmed down to a pulsating, high volume, low-viscosity lava flow. The rapid effusion rate of the magma as well as its high temperature and turbid nature helped carve the sinuous rille into the fractured and structurally weak Apennine Bench Formation underneath. Similar eruptions and subsequent flows were also created at Ann and joined to the main channel by a NE-trending secondary rille.

  19. Geological study of Ujungwatu area as support for NPP planning in Muria Central Java

    International Nuclear Information System (INIS)

    Srijono

    1995-01-01

    In accordance with growth of life in Java, the need for electricity is also growing accordingly. Efforts to provide electricity such as planning to build nuclear power plant (NPP) has been in the debate for a while. There are many factors to be considered in this planning, such as its environmental condition. Geological factor is one of the important one to be considered. Surface geological conditions around NPP area at Ujungwatu needed include stratigraphy, geological structure, geomorphology, and environmental geology. Geology in Ujungwatu at radius 5 km is quite interesting. This area is part of Genuk volcano group which is laid at south and Ujungwatu coast at north. Genuk mountain group is divided into mountain slope, mountain back, and mountain skeleton. Coastal area is composed of coast sand. Sand up to broken rock was present along river gullies. Others were volcanic rocks which was composed of lapili tuff, trachite, pyroxene andesite, tuff breccia, tephrite-andesitic tuff breccia, and basaltic tuff breccia. Volcanic structure is well reflected by morphological feature as lineaments and half circular form in mount Genuk. This structure was predominantly in NW-SE direction, and less dominant in NE-SW direction. Ujungwatu, from environmental view, is deserved to be developed because of its underground potency. Iron sand, fluvial tuff, kaolin, mud, riverstone, volcanic rock, tuff and marble were easily found underground. Those could be benefited to the people in the area so that it could change socio-economical condition of the people which in turn electricity is becoming a necessity. Last but not least, Portuguese fort as potential touristic object is also situated at Kartini beach near Ujungwatu. (author). 15 refs, 3 tabs, 5 figs

  20. The application of structure from motion (SfM) to identify the geological structure and outcrop studies

    Science.gov (United States)

    Saputra, Aditya; Rahardianto, Trias; Gomez, Christopher

    2017-07-01

    Adequate knowledge of geological structure is an essential for most studies in geoscience, mineral exploration, geo-hazard and disaster management. The geological map is still one the datasets the most commonly used to obtain information about the geological structure such as fault, joint, fold, and unconformities, however in rural areas such as Central Java data is still sparse. Recent progress in data acquisition technologies and computing have increased the interest in how to capture the high-resolution geological data effectively and for a relatively low cost. Some methods such as Airborne Laser Scanning (ALS), Terrestrial Laser Scanning (TLS), and Unmanned Aerial Vehicles (UAVs) have been widely used to obtain this information, however, these methods need a significant investment in hardware, software, and time. Resolving some of those issues, the photogrammetric method structure from motion (SfM) is an image-based method, which can provide solutions equivalent to laser technologies for a relatively low-cost with minimal time, specialization and financial investment. Using SfM photogrammetry, it is possible to generate high resolution 3D images rock surfaces and outcrops, in order to improve the geological understanding of Indonesia. In the present contribution, it is shown that the information about fault and joint can be obtained at high-resolution and in a shorter time than with the conventional grid mapping and remotely sensed topographic surveying. The SfM method produces a point-cloud through image matching and computing. This task can be run with open- source or commercial image processing and 3D reconstruction software. As the point cloud has 3D information as well as RGB values, it allows for further analysis such as DEM extraction and image orthorectification processes. The present paper describes some examples of SfM to identify the fault in the outcrops and also highlight the future possibilities in terms of earthquake hazard assessment, based on

  1. FY12 ARRA-NRAP Report – Studies to Support Risk Assessment of Geologic Carbon Sequestration

    Energy Technology Data Exchange (ETDEWEB)

    Cantrell, Kirk J.; Shao, Hongbo; Thompson, C. J.; Zhong, Lirong; Jung, Hun Bok; Um, Wooyong

    2011-09-27

    This report summarizes results of research conducted during FY2012 to support the assessment of environmental risks associated with geologic carbon dioxide (CO2) sequestration and storage. Several research focus areas are ongoing as part of this project. This includes the quantification of the leachability of metals and organic compounds from representative CO2 storage reservoir and caprock materials, the fate of metals and organic compounds after release, and the development of a method to measure pH in situ under supercritical CO2 (scCO2) conditions. Metal leachability experiments were completed on 6 different rock samples in brine in equilibrium with scCO2 at representative geologic reservoir conditions. In general, the leaching of RCRA metals and other metals of concern was found to be limited and not likely to be a significant issue (at least, for the rocks tested). Metals leaching experiments were also completed on 1 rock sample with scCO2 containing oxygen at concentrations of 0, 1, 5, and 10% to simulate injection of CO2 originating from the oxy-fuel combustion process. Significant differences in the leaching behavior of certain metals were observed when oxygen is present in the CO2. These differences resulted from oxidation of sulfides, release of sulfate, ferric iron and other metals, and subsequent precipitation of iron oxides and some sulfates such as barite. Experiments to evaluate the potential for mobilization of organic compounds from representative reservoir materials and cap rock and their fate in porous media (quartz sand) have been conducted. Results with Fruitland coal and Gothic shale indicate that lighter organic compounds were more susceptible to mobilization by scCO2 compared to heavier compounds. Alkanes demonstrated very low extractability by scCO2. No significant differences were observed between the extractability of organic compounds by dry or water saturated scCO2. Reaction equilibrium appears to have been reached by 96 hours. When

  2. PREVIOUS SECOND TRIMESTER ABORTION

    African Journals Online (AJOL)

    PNLC

    PREVIOUS SECOND TRIMESTER ABORTION: A risk factor for third trimester uterine rupture in three ... for accurate diagnosis of uterine rupture. KEY WORDS: Induced second trimester abortion - Previous uterine surgery - Uterine rupture. ..... scarred uterus during second trimester misoprostol- induced labour for a missed ...

  3. Structural Geology

    Science.gov (United States)

    Weber, John; Frankel, Kurt L.

    2011-05-01

    Structural geology and continental tectonics were ushered in to the modern quantitative age of geosciences with the arrival of the global plate tectonics paradigm (circa 1968), derived using new data from the oceans' depths, and John Ramsay's 1967 seminal work, Folding and Fracturing of Rocks. Fossen is to be applauded for crafting a unique, high-caliber, and accessible undergraduate textbook on structural geology that faithfully reflects this advance and the subsequent evolution of the discipline. This well-written text draws on Fossen's wealth of professional experience, including his broad and diverse academic research and experience in the petroleum industry. This book is beautifully illustrated, with excellent original color diagrams and with impressive color field photographs that are all keyed to locations and placed into geologic context.

  4. Quantification of rock heterogeneities by structural geological field studies combined with laboratory analyses

    Science.gov (United States)

    Reyer, Dorothea; Afsar, Filiz; Philipp, Sonja

    2013-04-01

    Heterogeneous rock properties in terms of layering and complex infrastructure of fault zones are typical in sedimentary successions. The knowledge of in-situ mechanical rock properties is crucial for a better understanding of processes such as fracturing and fluid transport in fractured reservoirs. To estimate in situ rock properties at different depths it is important to understand how rocks from outcrops differ from rocks at depth, for example due to alteration and removal of the overburden load. We aim at quantifying these properties by performing structural geological field studies in outcrop analogues combined with laboratory analyses of outcrop samples and drill-cores. The field studies focus on 1) fault zone infrastructure and 2) host rock fracture systems in two different study areas with different lithologies, the North German and the Bristol Channel Basin. We analyse quantitatively the dimension, geometry, persistence and connectivity of fracture systems. The field studies are complemented by systematic sampling to obtain the parameters Young's modulus, compressive and tensile strengths and elastic strain energy (also referred to as destruction work) from which we estimate rock and fracture toughnesses. The results show that in rocks with distinctive layering fractures are often restricted to individual layers, that is, stratabound. The probability of arrest seems to depend on the stiffness contrast between two single layers as well as on the thickness of the softer layer. The results also show that there are clear differences between fault zones in the different lithologies in terms of damage zone thicknesses and fracture system parameters. The results of laboratory analyses show that the mechanical properties vary considerably and for many samples there are clear directional differences. That is, samples taken perpendicular to layering commonly have higher stiffnesses and strengths than those taken parallel to layering. We combine the results of

  5. SMART-1 highlights and relevant studies on early bombardment and geological processes on rocky planets

    International Nuclear Information System (INIS)

    Foing, B H; Koschny, D; Frew, D; Almeida, M; Zender, J; Heather, D; Peters, S; Racca, G D; Marini, A; Stagnaro, L; Josset, J L; Beauvivre, S; Grande, M; Kellett, B; Huovelin, J; Nathues, A; Mall, U; Ehrenfreund, P; McCannon, P

    2008-01-01

    present here SMART-1 results relevant to the study of the early bombardment and geological processes on rocky planets. Further information and updates on the SMART-1 mission can be found on the ESA Science and Technology web pages, at: http://sci.esa.int/smart-1/

  6. Studies in iodine metabolism: 33 year summary, 1948-1979 (as previously submitted) with appendix, 1979-1982

    International Nuclear Information System (INIS)

    Middlesworth, L.V.

    1982-01-01

    The results of research into iodine metabolism from 1948 to 1982 are summarized. Study areas included the monitoring of iodine 131 from fallout in the thyroid glands of cattle and humans, the biological functions and metabolism of thyroid hormones, and methods to reduce the retention of radioiodine in the thyroid

  7. Fever-Induced Brugada Syndrome Is More Common Than Previously Suspected: A Cross-Sectional Study from an Endemic Area.

    Science.gov (United States)

    Rattanawong, Pattara; Vutthikraivit, Wasawat; Charoensri, Attawit; Jongraksak, Tanawat; Prombandankul, Awapa; Kanjanahattakij, Napatt; Rungaramsin, Sakda; Wisaratapong, Treechada; Ngarmukos, Tachapong

    2016-03-01

    Brugada syndrome (BrS) is defined as presenting of type-1 Brugada pattern (BrP). BrS can also be induced by fever. This study demonstrated a highest prevalence of fever-induced BrS ever reported. During May 2014, febrile (oral temperature ≥ 38 °C) and nonfebrile patients underwent standard and high leads (V1 and V2 at 2nd intercostal space) electrocardiogram. Risk factor and cardiac symptoms were recorded. Patients with a persistent of type-1 BrP after fever had subsided were excluded. The prevalence of BrS, type-2 BrP and early repolarization pattern (ERP) were demonstrated. A total of 401 patients, 152 febrile, and 249 nonfebrile, were evaluated. BrS was identified in six febrile patients (five males and one female) and two males in nonfebrile patients. The study demonstrated higher prevalence of BrS in febrile group compared to nonfebrile group (4.0% vs 0.8%, respectively, P = 0.037). Among fever-induced BrS patients, three patients (50.0%) experienced cardiac symptoms before and at the time of presentation and two patients (33.3%) had history of first-degree relative sudden death. No ventricular arrhythmia was observed. All of type-1 BrP disappeared after fever had subsided. We found no difference in prevalence of type-2 BrP in febrile and nonfebrile group (2.0% vs 2.8%, respectively, P > 0.05) as well as ERP (3.3% vs 6.4%, respectively, P > 0.05). Our study showed a highest prevalence of fever induced BrS ever reported. A larger study of prevalence, risk stratification, genetic test and management of fever-induced BrS should be done, especially in an endemic area. © 2015, Wiley Periodicals, Inc.

  8. Venlafaxine extended release versus conventional antidepressants in the remission of depressive disorders after previous antidepressant failure: ARGOS study.

    Science.gov (United States)

    Baldomero, E Baca; Ubago, J Giner; Cercós, C Leal; Ruiloba, J Vallejo; Calvo, C García; López, R Prieto

    2005-01-01

    Serotonin-norepinephrine reuptake inhibitors (SNRIs) may be used as an alternative treatment for depressed patients who do not tolerate or respond adequately to treatment with a conventional antidepressant. This randomized, open-label, multicenter study compared the effectiveness of the SNRI venlafaxine extended release (VXR) with that of conventional antidepressants (CA) in patients who were referred to an outpatient psychiatric specialty care setting for treatment after failure to tolerate or respond to at least 4 weeks of treatment with a CA in a primary care setting. Patients with a Hamilton Depression Rating Scale (HAM-D17) score > or =17 were randomly assigned to treatment with an alternative CA or VXR. Remission was defined as a score < or =7 on the HAM-D17. Efficacy analyses were carried out on 3,097 patients from the intent-to-treat (ITT) population (1,632 VXR; 1,465 CA). The antidepressants prescribed most frequently in the CA group were paroxetine (21.3%), citalopram (20.1%), sertraline (19.1%), fluoxetine (17.0%), and mirtazapine (7.9%). After 24 weeks of treatment, the VXR group demonstrated a significantly higher remission rate than did the CA group (59.3% VXR; 51.5% CA; P<.0001; odds ratio: 1.37; 95% CI: 1.19-1.58; P<.01). Despite the limitations of the open design, the results of this study suggest that venlafaxine extended release may be more effective than the conventional antidepressants used in this study when treating depressed patients who do not tolerate or respond adequately to treatment with a conventional antidepressant.

  9. CHRONOVAC VOYAGEUR: A study of the immune response to yellow fever vaccine among infants previously immunized against measles.

    Science.gov (United States)

    Goujon, Catherine; Gougeon, Marie-Lise; Tondeur, Laura; Poirier, Béatrice; Seffer, Valérie; Desprès, Philippe; Consigny, Paul-Henri; Vray, Muriel

    2017-10-27

    For administration of multiple live attenuated vaccines, the Advisory Committee on Immunization Practices recommends either simultaneous immunization or period of at least 28days between vaccines, due to a possible reduction in the immune response to either vaccine. The main objective of this study was to compare the immune response to measles (alone or combined with mumps and rubella) and yellow fever vaccines among infants aged 6-24months living in a yellow fever non-endemic country who had receivedmeasles and yellow fever vaccines before travelling to a yellow fever endemic area. A retrospective, multicenter case-control study was carried out in 7 travel clinics in the Paris area from February 1st 2011 to march 31, 2015. Cases were defined as infants immunized with the yellow fever vaccine and with the measles vaccine, either alone or in combination with mumps and rubella vaccine, with a period of 1-27days between each immunization. For each case, two controls were matched based on sex and age: a first control group (control 1) was defined as infants having received the measles vaccine and the yellow fever vaccine simultaneously; a second control group (control 2) was defined as infants who had a period of more than 27days between receiving the measles vaccine and yellow fever vaccine. The primary endpoint of the study was the percentage of infants with protective immunity against yellow fever, measured by the titer of neutralizing antibodies in a venous blood sample. One hundred and thirty-one infants were included in the study (62 cases, 50 infants in control 1 and 19 infants in control 2). Of these, 127 (96%) were shown to have a protective titer of yellow fever antibodies. All 4 infants without a protective titer of yellow fever antibodies were part of control group 1. The measles vaccine, alone or combined with mumps and rubella vaccines, appears to have no influence on humoral immune response to the yellow fever vaccine when administered between 1 and 27

  10. Self-shielding effects in burnup of Gd used as burnable absorber. Previous studies on its experimental verification

    International Nuclear Information System (INIS)

    Abbate, Maximo J.; Sbaffoni, Maria M.

    2003-01-01

    Continuing with the domestic 'Burnable Absorbers Research Plan' studies were done to estimate self-shielding effects during Gd 2 O 3 burnup as burnable absorber included in fuel pins of a CAREM geometry. In this way, its burnup was calculated without and with self-shielding. For the second case, were obtained values depending on internal pin radius and the effective one for the homogenized pin. For Gd 157, the burnup corresponding to the first case resulted 52.6 % and of 1.23 % for the effective one. That shows the magnitude of the effects under study. Considering that is necessary to perform one experimental verification, also are presented calculational results for the case to irradiate a pellet containing UO 2 (natural) and 8 wt % of Gd 2 O 3 , as a function of cooling time, that include: measurable isotopes concentrations, expected activities, and photon spectra for conditions able to be compared with bidimensional calculations with self-shielding. The irradiation time was supposed 30 dpp using RA-3 reactor at 10 MW. (author)

  11. Groundwater Flow Modeling in the KURT site for a Case Study about a Hypothetical Geological Disposal Facility of Radioactive Wastes

    International Nuclear Information System (INIS)

    Ko, Nak Youl; Park, Kyung Woo; Kim, Kyung Su; Choi, Jong Won

    2012-01-01

    Groundwater flow simulations were performed to obtain data of groundwater flow used in a safety assessment for a hypothetical geological disposal facility assumed to be located in the KURT (KAERI Underground Research Tunnel) site. A regional scale modeling of the groundwater flow system was carried out to make boundary conditions for a local scale modeling. And, fracture zones identified at the study site were involved in the local scale groundwater flow model. From the results of the local scale modeling, a hydraulic head distribution was indicated and it was used in a particle tracking simulation for searching pathway of groundwater from the location of the hypothetical disposal facility to the surface where the groundwater reached. The flow distance and discharge rate of the groundwater in the KURT site were calculated. It was thought that the modeling methods used in this study was available to prepare the data of groundwater flow in a safety assessment for a geological disposal facility of radioactive wastes.

  12. A genome-wide association study confirms previously reported loci for type 2 diabetes in Han Chinese.

    Directory of Open Access Journals (Sweden)

    Bin Cui

    Full Text Available BACKGROUND: Genome-wide association study (GWAS has identified more than 30 loci associated with type 2 diabetes (T2D in Caucasians. However, genomic understanding of T2D in Asians, especially Han Chinese, is still limited. METHODS AND PRINCIPAL FINDINGS: A two-stage GWAS was performed in Han Chinese from Mainland China. The discovery stage included 793 T2D cases and 806 healthy controls genotyped using Illumina Human 660- and 610-Quad BeadChips; and the replication stage included two independent case-control populations (a total of 4445 T2D cases and 4458 controls genotyped using TaqMan assay. We validated the associations of KCNQ1 (rs163182, p = 2.085×10(-17, OR 1.28 and C2CD4A/B (rs1370176, p = 3.677×10(-4, OR 1.124; rs1436953, p = 7.753×10(-6, OR 1.141; rs7172432, p = 4.001×10(-5, OR 1.134 in Han Chinese. CONCLUSIONS AND SIGNIFICANCE: Our study represents the first GWAS of T2D with both discovery and replication sample sets recruited from Han Chinese men and women residing in Mainland China. We confirmed the associations of KCNQ1 and C2CD4A/B with T2D, with the latter for the first time being examined in Han Chinese. Arguably, eight more independent loci were replicated in our GWAS.

  13. Studies of cesium and strontium migration in unconsolidated Canadian geological materials

    International Nuclear Information System (INIS)

    Gillham, R.W.; Lindsay, L.E.; Reynolds, W.D.; Kewen, T.J.; Cherry, J.A.; Reddy, M.R.

    1981-06-01

    Distribution coefficients (Ksub(d)) were measured for cesium and strontium in 16 samples of Canadian unconsolidated geological materials. The samples were collected to cover a wide range of grain size, clay-mineral composition, cation exchange capacity and carbonate mineral content. Distribution coefficients ranged between 10 2 and 2.0 x 10 4 ml/g for cesium and between 2.5 and 10 2 ml/g for strontium, indicating that most unconsolidated geological materials have a substantial ability to retard the migration of cesium, while strontium could generally be expected to be somewhat more mobile. The measured K values were not significantly correlated with the measured soil properties, but appeared to be significantly affected by the background concentration of stable isotopes of the respective radionuclides

  14. Geologic map of Mars

    Science.gov (United States)

    Tanaka, Kenneth L.; Skinner, James A.; Dohm, James M.; Irwin, Rossman P.; Kolb, Eric J.; Fortezzo, Corey M.; Platz, Thomas; Michael, Gregory G.; Hare, Trent M.

    2014-01-01

    This global geologic map of Mars, which records the distribution of geologic units and landforms on the planet's surface through time, is based on unprecedented variety, quality, and quantity of remotely sensed data acquired since the Viking Orbiters. These data have provided morphologic, topographic, spectral, thermophysical, radar sounding, and other observations for integration, analysis, and interpretation in support of geologic mapping. In particular, the precise topographic mapping now available has enabled consistent morphologic portrayal of the surface for global mapping (whereas previously used visual-range image bases were less effective, because they combined morphologic and albedo information and, locally, atmospheric haze). Also, thermal infrared image bases used for this map tended to be less affected by atmospheric haze and thus are reliable for analysis of surface morphology and texture at even higher resolution than the topographic products.

  15. Geology of Io

    Science.gov (United States)

    Greeley, R.; Craddock, R. A.; Crown, D. A.; Leshin, L. A.; Schaber, G. G.

    1987-01-01

    Geologic mapping of the Jovian satellite Io has been completed at 1:15,000,000 scale for an area lying between +40 and -90 deg latitude and 230 and 45 deg longitude, which includes portions of the Ruwa Patera quadrangle (Ji2) and the Lerna Region (Ji4) and the westernmost section of the Colchis Region (Ji3). Image resolution in the mapped area is commonly 0.5 to 2 km/pxl. High resolution areas (less than .5 km/pxl) are located near the south pole (Lerna Region) and in eastern Ruwa Patera quadrangle. Geologic maps for the Ruwa Patera quadrangle (Ji2) and the Lerna Region (Ji4) have been produced at 1:5,000,000 scale. The present effort reexamines the previously mapped areas and synthesizes the geology of Io on a global scale.

  16. What does hydraulic tomography tell us about fractured geological media? A field study and synthetic experiments

    Science.gov (United States)

    Zha, Yuanyuan; Yeh, Tian-Chyi J.; Illman, Walter A.; Tanaka, Tatsuya; Bruines, Patrick; Onoe, Hironori; Saegusa, Hiromitsu

    2015-12-01

    Between 2005 and 2010, Japan Atomic Energy Agency conducted four long-term, independent pumping tests in a fractured granite formation at the Mizunami Underground Research Laboratory (MIU) site in Mizunami city, central Japan. During these tests, drawdowns were monitored at different depths along several deep boreholes. These tests become one of the few, if not the only, hydraulic tomographic survey conducted in the world over thousands of meters in a fractured geologic medium with several fault zones. We analyzed the drawdown-time data set associated with each pumping test independently, and then the data sets from all pumping tests jointly to derive the spatial distributions of hydraulic conductivity (K) and specific storage (Ss) of the medium. These estimated distributions revealed some large-scale high K and low K zones. While the low K zones corroborated well with known low permeable layers and fault based on geological investigations, there were no clear geological features that can be related to the large-scale high K zones. In order to understand and substantiate these high and low K zones, we simulated a hydraulic tomographic survey in a synthetic fractured aquifer, which bears similar geologic features (i.e., formations, fractures, and faults) at the MIU site, with exception that the hydraulic properties, fracture and fault distributions were known exactly. Results of the simulation show that not only are the identified high K zones related to fracture networks connected with pumping and observation locations of each pumping test but also their values reflect the degree of connectivity of the network. Afterward, we investigated the extent of the improvement of characterization of the fault and fractures through the use of deploying dense monitoring intervals and late-time flux measurements.

  17. Outline of performance assessment study on geological isolation system in Japan

    International Nuclear Information System (INIS)

    Masuda, S.; Umeki, H.; Ishiguro, K.; Suzuki, A.

    1990-01-01

    This paper discusses the goals of current R and D activities which are to ensure the feasibility of geological isolation of HLW in japan and then to establish the social acceptance. The strategic plan for overall performance assessment is examined. The plan includes scenario development by systematic approach and consequence analysis in which the emphasis of developing simulation models are mainly placed on near-field phenomena. Recent developments in performance assessment have been summarized

  18. Regional Geology of the Southern Lake Erie (Ohio) Bottom: A Seismic Reflection and Vibracore Study.

    Science.gov (United States)

    1982-12-01

    vibratory coring apparatus used to collect sediment cores is shown being lifted off the platform for deployment on the lake floor. A 36-meter-long scow from...the U.S. Army Engineer District, Buffalo, was used as the platform for phase II coring. The scow was transported by the Corps tugboat Washington (Fig...on the geologic history of the lake, and of use. II. PHYSICAL SETTING 1. Introduction. The Lake Erie basin is underlain by middle Paleozoic sedimentary

  19. Pore-scale studies of multiphase flow and reaction involving CO2 sequestration in geologic formations

    Science.gov (United States)

    Kang, Q.; Wang, M.; Lichtner, P. C.

    2008-12-01

    In geologic CO2 sequestration, pore-scale interfacial phenomena ultimately govern the key processes of fluid mobility, chemical transport, adsorption, and reaction. However, spatial heterogeneity at the pore scale cannot be resolved at the continuum scale, where averaging occurs over length scales much larger than typical pore sizes. Natural porous media, such as sedimentary rocks and other geological media encountered in subsurface formations, are inherently heterogeneous. This pore-scale heterogeneity can produce variabilities in flow, transport, and reaction processes that take place within a porous medium, and can result in spatial variations in fluid velocity, aqueous concentrations, and reaction rates. Consequently, the unresolved spatial heterogeneity at the pore scale may be important for reactive transport modeling at the larger scale. In addition, current continuum models of surface complexation reactions ignore a fundamental property of physical systems, namely conservation of charge. Therefore, to better understand multiphase flow and reaction involving CO2 sequestration in geologic formations, it is necessary to quantitatively investigate the influence of the pore-scale heterogeneity on the emergent behavior at the field scale. We have applied the lattice Boltzmann method to simulating the injection of CO2 saturated brine or supercritical CO2 into geological formations at the pore scale. Multiple pore-scale processes, including advection, diffusion, homogeneous reactions among multiple aqueous species, heterogeneous reactions between the aqueous solution and minerals, ion exchange and surface complexation, as well as changes in solid and pore geometry are all taken into account. The rich pore scale information will provide a basis for upscaling to the continuum scale.

  20. Comparative study of a novel application of automated HR HPV assay and stability in a previously untested Preservative media.

    Science.gov (United States)

    Morel, Mike E; McBride, Simon E; Gomez, Maria P

    2017-12-01

    The suitability and stability of cervical cells in Novaprep media (NHQ) for certain HPV assays is unknown. We evaluated the accuracy of an automated HPV assay (Abbott RealTime HR HPV) for cervical cells prepared in NHQ and NHQ with a pre-treatment to mimic a worst case clinical use, compared to the assay manufacturers media; repeatability and reproducibility of HPV results and the stability of detectable HPV in NHQ over time compared to CE marked liquid based cytology preservatives. Cell lines were used to simulate patient samples. Cells stored in NHQ produced accurate, repeatable and reproducible results. Stability in NHQ was comparable to the best performing LBC, with at least 7 months' stability at 18-25°C, 2-8°C, -20°C and -80°C; and at least 3 months' stability at 40°C. Similar results were obtained for pre-treated NHQ except only 3.5 months' stability at 18-25°C. Cell line samples in all media and concentrations tested were detected appropriately by the assay. Based on this first stage validation analytical study, cervical cells stored in NHQ are suitable for the Realtime HPV assay. There should be no reservations for inclusion of NHQ in any further validation and clinical performance evaluation of this assay. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  1. Study on improvement in reliability of inventory assessment in vitrified waste for long-term safety of geological disposal

    International Nuclear Information System (INIS)

    Ishikawa, Masumi; Kaneko, Satoru; Kitayama, Kazumi; Ishiguro, Katsuhiko; Ueda, Hiroyoshi; Wakasugi, Keiichiro; Shinohara, Nobuo; Okumura, Keisuke; Chino, Masamichi; Moriya, Noriyasu

    2009-01-01

    Since quality control issues for vitrified waste are defined mainly with the focus on the transport and interim storage of the waste rather than the long-term safety of geological disposal, they do not cover inventories of long-lived nuclides that are of most interest in the safety assessment of geological disposal. Therefore, we suggest a flow chart for the assessment of inventories of long-lived nuclides in the vitrified waste focusing on the measured values. This includes an indirect assessment with indicative nuclides that have been already measured in the returned vitrified wastes from abroad. In order to apply this flow chart for commercial operation, its applicability should be examined for cases with a variation in burn-up history and with an uncertainty associated with carry-over fraction at reprocessing. We started an R and D program to examine the applicability as well as to improve the reliability of the nuclide generation/decay code and the nuclear data library using liquid waste from spent fuel with a clear irradiation history. To solve the issue of quality control for vitrified waste, a comprehensive study is needed in aspects not only of geological disposal field but also of operation of a nuclear power plant, reprocessing of spent fuel and vitrification of liquid waste. This study is a pioneering study conducted to integrate them. (author)

  2. Knowledge of stroke risk factors among primary care patients with previous stroke or TIA: a questionnaire study

    Directory of Open Access Journals (Sweden)

    Strender Lars-Erik

    2010-06-01

    Full Text Available Abstract Background Survivers of stroke or transient ischaemic attacks (TIA are at risk of new vascular events. Our objective was to study primary health care patients with stroke/TIA regarding their knowledge about risk factors for having a new event of stroke/TIA, possible associations between patient characteristics and patients' knowledge about risk factors, and patients' knowledge about their preventive treatment for stroke/TIA. Methods A questionnaire was distributed to 240 patients with stroke/TIA diagnoses, and 182 patients (76% responded. We asked 13 questions about diseases/conditions and lifestyle factors known to be risk factors and four questions regarding other diseases/conditions ("distractors". The patients were also asked whether they considered each disease/condition to be one of their own. Additional questions concerned the patients' social and functional status and their drug use. The t-test was used for continuous variables, chi-square test for categorical variables, and a regression model with variables influencing patient knowledge was created. Results Hypertension, hyperlipidemia and smoking were identified as risk factors by nearly 90% of patients, and atrial fibrillation and diabetes by less than 50%. Few patients considered the distractors as stroke/TIA risk factors (3-6%. Patients with a family history of cardiovascular disease, and patients diagnosed with carotid stenosis, atrial fibrillation or diabetes, knew these were stroke/TIA risk factors to a greater extent than patients without these conditions. Atrial fibrillation or a family history of cardiovascular disease was associated with better knowledge about risk factors, and higher age, cerebral haemorrhage and living alone with poorer knowledge. Only 56% of those taking anticoagulant drugs considered this as intended for prevention, while 48% of those taking platelet aggregation inhibitors thought this was for prevention. Conclusions Knowledge about hypertension

  3. Geologic and Seismologic Investigation

    Science.gov (United States)

    1988-12-01

    Utah, Embankment Criteria and Performance Report, August 1994 2. Caliente Creek Stream Group Investigation California, Draft Feasibility Report. June...trenching and soil-stratigraphic investigations east of Sacramento, north of the study area ( Tierra Engineering Consultants, 1983) at Folsom Dam showed...Geologic Map of California, Olaf P. Jenkins edition, Mariposa Sheet: California Division qf Mines and Geology, Scale 1:250,000. Tierra Entgineering

  4. Geology and geohydrology of the east Texas Basin. Report on the progress of nuclear waste isolation feasibility studies (1979)

    International Nuclear Information System (INIS)

    Kreitler, C.W.; Agagu, O.K.; Basciano, J.M.

    1980-01-01

    The program to investigate the suitability of salt domes in the east Texas Basin for long-term nuclear waste repositories addresses the stability of specific domes for potential repositories and evaluates generically the geologic and hydrogeologic stability of all the domes in the region. Analysis during the second year was highlighted by a historical characterization of East Texas Basin infilling, the development of a model to explain the growth history of the domes, the continued studies of the Quaternary in East Texas, and a better understanding of the near-dome and regional hydrology of the basin. Each advancement represents a part of the larger integrated program addressing the critical problems of geologic and hydrologic stabilities of salt domes in the East Texas Basin

  5. Geologic studies on the Rio Una region (Iguape - Sao Paulo County), Brazil, for the construction of nuclear power plants

    International Nuclear Information System (INIS)

    Hassano, S.; Mueller, M.; Stein, J.H.

    1984-01-01

    The main objective of the project was the geological and seismological characterization of 230 Km 2 along the coastal region between the Barro Branco and Jureia massifs in order to pinpoint one or more local areas showing adequate geological, morphological and geotechnical conditions suitable for construction of nuclear power plants. Results of the investigations, as well as the methodology used for determination of main interesting areas are presented. The best areas for construction are believed to be situated along the coast where Precambrian basement rocks crop out close to the shoreline. The Tertiary-Quaternary sedimentary cover reaches a thickness of 50 or more meters and the character of the sediments does not allow direct emplacement of foundations for heavy-weight constructions. Historical analysis of seismic activity of the region, as well as the study of faults and fracture zones identified in the area demonstrate the absence of active faults such as defined by internationally accepted safety criteria. (Author) [pt

  6. Geological mapping by geobotanical and geophysical means: a case study from the Bükk Mountains (NE Hungary)

    Science.gov (United States)

    Németh, Norbert; Petho, Gabor

    2009-03-01

    Geological mapping of an unexposed area can be supported by indirect methods. Among these, the use of mushrooms as geobotanical indicators and the shallow-penetration electromagnetic VLF method proved to be useful in the Bükk Mountains. Mushrooms have not been applied to geological mapping before. Common species like Boletus edulis and Leccinum aurantiacum are correlated with siliciclastic and magmatic formations while Calocybe gambosa is correlated with limestone. The validity of this correlation observed in the eastern part of the Bükk Mts. was controlled on a site where there was an indicated (by the mushrooms only) but unexposed occurrence of siliciclastic rocks not mapped before. The extent and structure of this occurrence were explored with the VLF survey and a trial-and-error method was applied for the interpretation. This case study presented here demonstrates the effectiveness of the combination of these relatively simple and inexpensive methods.

  7. Technical support for GEIS: radioactive waste isolation in geologic formations. Volume 8. Repository preconceptual design studies: salt

    International Nuclear Information System (INIS)

    1978-04-01

    This volume, Volume 8 ''Repository Preconceptual Design Studies: Salt,'' is one of a 23-volume series, ''Technical Support for GEIS: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-36, which supplements the ''Contribution to Draft Generic Environmental Impact Statement on Commercial Waste Management: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-44. The series provides a more complete technical basis for the preconceptual designs, resource requirements, and environmental source terms associated with isolating commercial LWR wastes in underground repositories in salt, granite, shale and basalt. Wastes are considered from three fuel cycles: uranium and plutonium recycling, no recycling of spent fuel and uranium-only recycling. This document describes a preconceptual design for a nuclear waste storage facility in salt. The facility design consists of several chambers excavated deep within a geologic formation together with access shafts and supportive surface structures. The facility design provides for: receiving and unloading waste containers; lowering them down shafts to the mine level; transporting them to the proper storage area, and emplacing them in mined storage rooms. Drawings of the facility design are contained in TM-36/9, ''Drawings for Repository Preconceptual Design Studies: Salt.''

  8. Technical support for GEIS: radioactive waste isolation in geologic formations. Volume 10. Repository preconceptual design studies: granite

    International Nuclear Information System (INIS)

    1978-04-01

    This volume, Volume 10 ''Repository Preconceptual Design Studies: Granite,'' is one of a 23-volume series, ''Technical Support for GEIS: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-36, which supplements the ''Contribution to Draft Generic Environmental Impact Statement on Commercial Waste Management: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-44. The series provides a more complete technical basis for the preconceptual designs, resource requirements, and environmental source terms associated with isolating commercial LWR wastes in underground repositories in salt, granite, shale and basalt. Wastes are considered from three fuel cycles: uranium and plutonium recycling, no recycling of spent fuel and uranium-only recycling. This document describes a preconceptual design for a nuclear waste storage facility in granite. The facility design consists of several chambers excavated deep within a geologic formation together with access shafts and supportive surface structures. The facility design provides for: receiving and unloading waste containers; lowering them down shafts to the mine level; transporting them to the proper storage area, and emplacing them in mined storage rooms. Drawings of the facility design are contained in TM-36/11, ''Drawings for Repository Preconceptual Design Studies: Granite.''

  9. Additions and corrections to the bibliography of geologic studies, Columbia Plateau (Columbia River Besalt) and adjacent Areas, in Idaho, 1980

    International Nuclear Information System (INIS)

    Strowd, W.

    1980-01-01

    This bibliography is an update to Idaho Bureau of Mines and Geology Open-File Report 78-6, Bibliography of Geological Studies, Columbia Plateau (Columbia River Basalt Group) and adjacent areas in Idaho (also known as Rockwell Hanford Operations' contractor report RHO-BWI-C-44). To keep the original document current, this additions and corrections report was prepared for the Basalt Waste Isolation Project of Rockwell Hanford Operations. This update is supplementary; therefore, references cited in the original document have not been included here. What is included are materials that have become available since the original publication and pertinent literature that had originally been overlooked. Accompany this updated bubliography are index maps that show locations of geologic studies and geochemical petrographic, remanent paleomagnetic, and radiometric age-dated sites within the Columbia River Basalt Group field within Idaho; also identified are archeological sites, test wells, mines, quarries, and other types of excavations. References on the index maps are keyed to the bibliography and cover the Spokane, Pullman, Hamilton, Grangeville, Elk City, Baker, Boise, and Jordan Valley Army Map Service two-degree quadrangles

  10. Geologic and Geophysicsal Studies of Natural Hazards and Risks in the Gulf of Peter the Great, Japan Sea

    Science.gov (United States)

    Anokhin, Vladimir; Shcherbakov, Viktor; Motychko, Viktor; Slinchenkov, Vladimir; Sokolov, Georgy; Kotov, Sergey; Kartashov, Sergey

    2013-04-01

    The area of the Gulf of Peter the Great is socially, economically and culturally one of the most important regions for the Russian Far East. At the same time, there have been reported palpable natural hazards, which pose a real threat to local infrastructure. Complex field team of the Gramaberg VNIIOkeangeologia institute carried out geological and geophysical studies of natural hazards in the water area and coastal zone of the gulf in the summer and autumn of 2012. The research program included - geodetic deformation monitoring of the coastal zone by the HDS 3000 Leica tachometer; - echo sounding of the underwater part of the coastal slope by the LCX-37C depth sounder equipped with active external 12-channel GPS Lowrance antenna LGC-3000; - high-frequency acoustic profiling by GeoPulse Subbotom Profilier with oscillator frequency of 12.2 kHz for the study of bottom sediments to a depth of 40 m; - hydromagnetic measurements by SeaSPY Marine Magnetics magnetometer for investigation of deep geological structure; - sonar measurements by GEO SM C-MAX, 325 kHz frequency emitters for studying seafloor features; - studies of the water column (sensing and sampling); - bottom sediment sampling. Analytic work was performed by mass spectrometry, atomic absorption spectrophotometry, chromatography, gas chromatography-mass spectrometry, gamma spectrometry and included the following. For water - the content of Fe, Mn, Cd, As, Pb, Cu, Co, Ni, Cr, Zn, Hg in solution and in suspension, polycyclic aromatic compounds, organochlorine pesticides, oil, methane. For sediments - grade analysis, mineralogical analysis of sand, determination of Fe, Mn, Cd, As, Pb, Cu, Co, Ni, Cr, Zn, Hg content; identification of petroleum products, polychlorinated biphenyls, organochlorine pesticides, the specific activity of Cs-137. As a result, a set of geological maps was composed: maps of pre-Quaternary and Quaternary rocks and deposits, lithological map, geomorphological map, map of engineering

  11. Geologic mapping of the Reull Vallis Region, Mars

    Science.gov (United States)

    Mest, Scott C.; Crown, David A.

    1997-03-01

    Geologic mapping of the Reull Vallis region is being undertaken in order to determine the sequence of events that formed the Reull Vallis outflow channel system and to understand the geologic processes that modified the Martian southern highlands. The region is situated on the northeast rim of the Hellas Basin in the heavily cratered highlands and shows evidence of fluvial activity, volcanism, mass wasting, and tectonism. The western portion of the Reull Vallis region was previously mapped in a study of Hadriaca Patera.

  12. A SKOS-based multilingual thesaurus of geological time scale for interopability of online geological maps

    NARCIS (Netherlands)

    Ma, X.; Carranza, E.J.M.; Wu, C.; Meer, F.D. van der; Liu, G.

    2011-01-01

    The usefulness of online geological maps is hindered by linguistic barriers. Multilingual geoscience thesauri alleviate linguistic barriers of geological maps. However, the benefits of multilingual geoscience thesauri for online geological maps are less studied. In this regard, we developed a

  13. Building The Bigger Picture - Using a field study geology programme to link and contextualise classroom topics.

    Science.gov (United States)

    Allen, Lesley

    2013-04-01

    Cornwall, UK, has been designated a World Heritage Site for industrial heritage, based on the extensive mining history built around hydrothermal deposits of tin and copper suite deposits. These deposits are found in a very varied and complex geological setting. The tectonic activity which emplaced the deposits also produced intense folding and faulting of Carboniferous and Devonian marine sediments, major and minor igneous intrusions, regional and contact metamorphism, and the emplacement of an ophiolite sequence on the Lizard peninsula. The region is targeted by college and university geology student groups from across the UK. It is also the home of the world famous Camborne School of Mines, part of the University of Exeter. We have developed a comprehensive series of field visits to cover all these geological aspects. We also use the history of mining as a context within which to teach the social, environmental and economic aspects of the geology curriculum at A Level. By this means we can reveal how disparate geological topics link together through 3 physical dimensions plus time. Field visits motivate students; they enthuse and excite them and help them to understand the large-scale and 3D visualisation aspects of geology, the timescales involved, and also assist students in developing observational and practical field and mapping skills. The series of visits also helps to bring many aspects of the curriculum together into a more complete picture. Site 1 - Bude. Intense folding of marine sediments with tectonic and sedimentary structures in cyclical sands and shales and some turbidites. Competent and incompetent rocks, axial planar cleavage, etc. Site 2 - Praa Sands. Minor porphyritic intrusion with baked & chilled margins and flow aligned feldspars. (Also incidental raised beach due to post-glacial isostatic rebound.) Site 3 - Rinsey Cove. Contact zone where 'roof' of major granitic intrusion intrudes slates. Pegmatites, classic marginal features, xenoliths

  14. Geology Fulbrights

    Science.gov (United States)

    Fulbright grants in geology for 1988-89 remain open. Specific opportunities are available in Egypt, German Democratic Republic, Hungary, Iceland, Iraq, Kuwait, Morocco, Mozambique, Oman, Poland, Sudan, Syria, Tanzania, Turkey, U.S.S.R., West Bank, Yemen, and Zimbabwe. Other countries are also open to applications in any discipline, and geology is among their preferred fields.The grants are available until awarded and are open only to U.S. citizens. In Central and South America and French-speaking Africa, knowledge of host-country language is required. For more information, contact the Council for International Exchange of Scholars (CIES), 11 Dupont Circle N.W., Suite 300, Washington, DC 20036; tel. 202-939-5401.

  15. A Study of the Relationship of Geological Formation to the NORM

    International Nuclear Information System (INIS)

    Bursh, Talmage P.; Chriss, Derald

    1999-01-01

    Naturally Occurring Radioactive Materials (NORM) is a common and costly contaminant of produced waters associated with natural gas production and exploration. One way of combating this problem is by identifying the problem beforehand. Our approach to this problem involves development of NORM prediction capabilities based on the geological environment. During the tenth quarter of this project, emphasis again remained on two major tasks; identifying new sampling sites and seeking approval for final project revisions. In light of the delays experienced, the project has been granted a one year extension, and a revision is currently under review

  16. A study on nuclide migration in buffer materials and rocks for geological disposal of radioactive waste

    International Nuclear Information System (INIS)

    Sato, Haruo

    1998-01-01

    This thesis summarizes the results investigated in order to establish a basic theory on the predictive method of diffusion coefficients of nuclides in compacted sodium bentonite which is a candidate buffer material and in representative rocks for the geological disposal of radioactive waste by measuring the pore structural factors of the compacted bentonite and rocks such as porosity and tortuosity, measuring diffusion coefficients of nuclides in the bentonite and rocks, acquiring basic data on diffusion and developing diffusion models which can quantitatively predict nuclide migration in long-term. (J.P.N.). 117 refs

  17. A Study of the Relationship of Geological Formation to the NORM

    International Nuclear Information System (INIS)

    Bursh, Talmage P.; Chriss, Derald

    1999-01-01

    Naturally Occurring Radioactive Materials (NORM) is a common and costly contaminant of produced waters associated with natural gas production and exploration. One way of combating this problem is by identifying the problem beforehand. Our approach to this problem involves development of NORM prediction capabilities based on the geological environment. During quarter fifteen of this project, work has continued under the recently approved revisions. We have selected sampling sites and are awaiting samples for analysis. In addition, the QA/QC plans are in the final stages in anticipation of sample acquisition

  18. Geo-Chemo-Mechanical Studies for Permanent CO{sub 2} Storage in Geologic Reservoirs

    Energy Technology Data Exchange (ETDEWEB)

    Kelemen, Peter; Park, Ah-hyung; Matter, Jurg; Gadikota, Greeshma; Lisabeth, Harrison; Zhu, Wenlu

    2013-09-30

    This two-pronged study investigated the rates and mechanisms of formation of Ca and Mg carbonate minerals via reaction of aqueous fluids with silicate minerals and rocks, and the geomechanical effects of such reactions. The kinetic studies focused on the separation of variables, following from previous studies demonstrating rapid formation of carbonates via reaction of the mineral olivine with aqueous fluids rich in NaHCO{sub 3} (plus KHCO{sub 3} and RbHCO{sub 3}) and NaCl at a high partial pressure of CO{sub 2}. We wished to separate and quantify the effects of NaHCO{sub 3} and NaCl, and to investigate whether bicarbonate-rich, aqueous fluids would also cause rapid formation of carbonates via reaction with other minerals and rocks. Further, we wished to improve upon previous work by adding precise characterization of grain size distributions and surface area, and their changes as a result of reaction. We confirmed previous reports of very rapid olivine carbonation. We found that at a given temperature and CO{sub 2} partial pressure the previously observed rate enhancement in olivine carbonation is due mainly to NaHCO{sub 3}, and not to dissolved NaCl. Further, though reaction of the mineral plagioclase, and two rock compositions, were all faster in the presence of NaHCO{sub 3}-rich fluids, compared with saline and de-ionized water, they were all much slower than reaction of olivine. In the experiments showing the fastest reaction rate, average grain size tended to increase during experiments, presumably due to dissolution of small reactant grains plus growth of product phases on reactant surfaces. Porosity/surface area of grains tended to change with reaction progress, due to the formation of dissolution pits and irregular growth of product phases on reactant grain surfaces. Development of a passivating phase (e.g., a layer of silica) due to incongruent dissolution of solid reactants and/or precipitation of solid products was detected, but was relatively minor and

  19. Experimental study of the time of dissolution of the RN 222 in water and some implications in geology

    International Nuclear Information System (INIS)

    Garcia Vindas, J.R.

    2001-01-01

    The study of radon like a tracer in Geology involves the study of radon's dissolution in water. The objective of this work is to study the time required to dissolve a volume of radon in water and to expel it from water. For this purpose a device has been built that allows dissolving or expelling a volume of radon in water. The results show that it is possible to dissolve or expel, in a short time, a volume of radon from water. (Author) [es

  20. Study to optimize a disposal tunnel layout taking into account heterogeneous characteristics of the geological environment

    International Nuclear Information System (INIS)

    Suyama, Yasuhiro; Toida, Masaru; Yanagizawa, Koichi

    2007-01-01

    The geological environment has spatially heterogeneous characteristics with varied host rock types, fractures and so on. In this case the generic disposal tunnel layout, which has been designed by JNC, is not the most suitable for HLW disposal in Japan. The existence of spatially heterogeneous characteristics means that in the repository region there exist sub-regions that are more favorable from the perspective of long-term safety and ones that are less favorable. In order that the spatially heterogeneous environment itself may be utilized most effectively as an NBS, an alternative design of disposal tunnel layout is required. Focusing on the geological environment with spatially heterogeneous characteristics, the authors have developed an alternative design of disposal tunnel layout. The alternative design adopts an optimization approach using a 'variable disposal tunnel layout'. The optimization approach minimizes the number of locations where major water conducting fractures are intersected, and maximizes the number of emplacement locations for waste packages. This paper will outline the variable disposal tunnel layout and its applicability. (author)

  1. Multidisciplinary study of Wyoming test sites. [hydrology, biology, geology, lithology, geothermal, and land use

    Science.gov (United States)

    Houston, R. S. (Principal Investigator); Marrs, R. W.; Agard, S. S.; Downing, K. G.; Earle, J. L.; Froman, N. L.; Gordon, R.; Kolm, K. E.; Tomes, B.; Vietti, J.

    1974-01-01

    The author has identified the following significant results. Investigation of a variety of applications of EREP photographic data demonstrated that EREP S-190 data offer a unique combination of synoptic coverage and image detail. The broad coverage is ideal for regional geologic mapping and tectonic analysis while the detail is adequate for mapping of crops, mines, urban areas, and other relatively small features. The investigative team at the University of Wyoming has applied the EREP S-190 data to: (1) analysis of photolinear elements of the Powder River Basin, southern Montana, and the Wind River Mountains; (2) drainage analysis of the Powder River Basin and Beartooth Mountains; (3) lithologic and geologic mapping in the Powder River Basin, Black Hills, Green River Basin, Bighorn Basin and Southern Bighorn Mountains; (4) location of possible mineralization in the Absaroka Range; and (5) land use mapping near Riverton and Gillette. All of these applications were successful to some degree. Image enhancement procedures were useful in some efforts requiring distinction of small objects or subtle contrasts.

  2. Great Meteor East (distal Madeira Abyssal Plain): geological studies of its suitability for disposal of heat-emitting radioactive wastes

    International Nuclear Information System (INIS)

    Searle, R.C.; Schultheiss, P.J.; Weaver, P.P.E.; Noel, M.; Kidd, R.B.; Jacobs, C.L.; Huggett, Q.J.

    1985-01-01

    This report summarises geological and geophysical studies carried out by the Institute of Oceanographic Sciences up to December 1983 in an area of the Madeira Abyssal Plain in order to assess its suitability for the disposal of heat-emitting radioactive waste. The results of work carried out in the same area by the Rijks Geologische Dienst of the Netherlands are also reviewed in the report. Other oceanographic studies in the area in the fields of geochemistry, biology and oceanography are briefly touched upon. (author)

  3. Geologic Framework Model (GFM2000)

    Energy Technology Data Exchange (ETDEWEB)

    T. Vogt

    2004-08-26

    The purpose of this report is to document the geologic framework model, version GFM2000 with regard to input data, modeling methods, assumptions, uncertainties, limitations, and validation of the model results, and the differences between GFM2000 and previous versions. The version number of this model reflects the year during which the model was constructed. This model supersedes the previous model version, documented in Geologic Framework Model (GFM 3.1) (CRWMS M&O 2000 [DIRS 138860]). The geologic framework model represents a three-dimensional interpretation of the geology surrounding the location of the monitored geologic repository for spent nuclear fuel and high-level radioactive waste at Yucca Mountain. The geologic framework model encompasses and is limited to an area of 65 square miles (168 square kilometers) and a volume of 185 cubic miles (771 cubic kilometers). The boundaries of the geologic framework model (shown in Figure 1-1) were chosen to encompass the exploratory boreholes and to provide a geologic framework over the area of interest for hydrologic flow and radionuclide transport modeling through the unsaturated zone (UZ). The upper surface of the model is made up of the surface topography and the depth of the model is constrained by the inferred depth of the Tertiary-Paleozoic unconformity. The geologic framework model was constructed from geologic map and borehole data. Additional information from measured stratigraphic sections, gravity profiles, and seismic profiles was also considered. The intended use of the geologic framework model is to provide a geologic framework over the area of interest consistent with the level of detailed needed for hydrologic flow and radionuclide transport modeling through the UZ and for repository design. The model is limited by the availability of data and relative amount of geologic complexity found in an area. The geologic framework model is inherently limited by scale and content. The grid spacing used in the

  4. Geologic Framework Model (GFM2000)

    International Nuclear Information System (INIS)

    T. Vogt

    2004-01-01

    The purpose of this report is to document the geologic framework model, version GFM2000 with regard to input data, modeling methods, assumptions, uncertainties, limitations, and validation of the model results, and the differences between GFM2000 and previous versions. The version number of this model reflects the year during which the model was constructed. This model supersedes the previous model version, documented in Geologic Framework Model (GFM 3.1) (CRWMS M and O 2000 [DIRS 138860]). The geologic framework model represents a three-dimensional interpretation of the geology surrounding the location of the monitored geologic repository for spent nuclear fuel and high-level radioactive waste at Yucca Mountain. The geologic framework model encompasses and is limited to an area of 65 square miles (168 square kilometers) and a volume of 185 cubic miles (771 cubic kilometers). The boundaries of the geologic framework model (shown in Figure 1-1) were chosen to encompass the exploratory boreholes and to provide a geologic framework over the area of interest for hydrologic flow and radionuclide transport modeling through the unsaturated zone (UZ). The upper surface of the model is made up of the surface topography and the depth of the model is constrained by the inferred depth of the Tertiary-Paleozoic unconformity. The geologic framework model was constructed from geologic map and borehole data. Additional information from measured stratigraphic sections, gravity profiles, and seismic profiles was also considered. The intended use of the geologic framework model is to provide a geologic framework over the area of interest consistent with the level of detailed needed for hydrologic flow and radionuclide transport modeling through the UZ and for repository design. The model is limited by the availability of data and relative amount of geologic complexity found in an area. The geologic framework model is inherently limited by scale and content. The grid spacing used in

  5. Studies of nuclear waste migration in geologic media. Annual report, October 1978-September 1979

    International Nuclear Information System (INIS)

    Seitz, M.G.; Rickert, P.G.; Couture, R.A.; Williams, J.; Meldgin, N.; Fried, S.M.; Friedman, A.M.; Steindler, M.J.

    1980-01-01

    Experimental results obtained this year confirm the results obtained in previous years - that nuclides migrating by fluid flow in rock often exhibit complex behavior not predicted by simple chromatographic-type models. A phenomenon found previously to lead to complex behavior for leached radionuclides is that the amount of adsorbed nuclide was not proportional to the nuclide concentration in solution (nonlinear adsorption isotherm). For cesium adsorption on limestone and on basalt, nonlinear isotherms were found this year to occur in the range of cesium concentrations in the groundwater of about 10 -3 to 10 -9 M. Because cesium concentrations in this range can readily be attained by the leaching of solid waste by groundwater, the effects of nonlinear isotherms are germane to nuclide migration. This dependence of cesium migration on the leached concentration of cesium emphasizes the importance of treating the leaching and migration processes simultaneously such as is done in the leach-migration experiments performed in this work. The existence of nonlinear isotherms precludes the use of a single partition coefficient (K/sub d/) to describe cesium migration at an arbitrary cesium concentration above 10 -9 M. Nonetheless, nonlinear isotherms can be studied experimentally (e.g., to give K/sub d/ as a function of concentration) and effects of nonlinear adsorption can be predicted quantitatively. Comparison of results from column and batch tests indicate that, in addition to nonlinear adsorption, kinetic effects need to be considered in predicting nuclide migration from the partition coefficients measured in batch tests. Results of batch experiments of 2 weeks or longer duration pertained to migration expected only at the very lowest (< 50 m/y) groundwater flow rates of interest

  6. Polychlorinated biphenyl exposure, diabetes and endogenous hormones: a cross-sectional study in men previously employed at a capacitor manufacturing plant.

    Science.gov (United States)

    Persky, Victoria; Piorkowski, Julie; Turyk, Mary; Freels, Sally; Chatterton, Robert; Dimos, John; Bradlow, H Leon; Chary, Lin Kaatz; Burse, Virlyn; Unterman, Terry; Sepkovic, Daniel W; McCann, Kenneth

    2012-08-29

    Studies have shown associations of diabetes and endogenous hormones with exposure to a wide variety of organochlorines. We have previously reported positive associations of polychlorinated biphenyls (PCBs) and inverse associations of selected steroid hormones with diabetes in postmenopausal women previously employed in a capacitor manufacturing plant. This paper examines associations of PCBs with diabetes and endogenous hormones in 63 men previously employed at the same plant who in 1996 underwent surveys of their exposure and medical history and collection of bloods and urine for measurements of PCBs, lipids, liver function, hematologic markers and endogenous hormones. PCB exposure was positively associated with diabetes and age and inversely associated with thyroid stimulating hormone and triiodothyronine-uptake. History of diabetes was significantly related to total PCBs and all PCB functional groupings, but not to quarters worked and job score, after control for potential confounders. None of the exposures were related to insulin resistance (HOMA-IR) in non-diabetic men. Associations of PCBs with specific endogenous hormones differ in some respects from previous findings in postmenopausal women employed at the capacitor plant. Results from this study, however, do confirm previous reports relating PCB exposure to diabetes and suggest that these associations are not mediated by measured endogenous hormones.

  7. Paleocorrosion studies in deep sea sediments and the geological disposal of nuclear wastes

    International Nuclear Information System (INIS)

    Fehrenbach, L.; Maurette, M.; Guichard, F.; Havette, A.; Monaco, A.

    1984-01-01

    Uncertainties still surround assessment of the safety of disposal of nuclear wastes incorporated into 'radwaste' matrices. This is mostly due to the long time required for radioactive decay of 237 Np. The present work explores the usefulness of an experimental approach in 'paleocorrosion', which should help in minimizing such uncertainties. In this approach, polished sections of sediments containing high concentrations of natural analogues of radwaste matrices are subjected to element micromapping. Thus it is possible to characterize the long-term interactions of such analogues in their geological repositories, and to identify which generate reaction aureoles and protective and/or unprotective coatings. These analogues include grains incorporated in deep sea sediments (uraninite and quartz from the Oklo uranium ore deposit; volcanic ash particles; magnetic cosmic spherules). The present results indicate that uraninite should be a much more durable radwaste matrix than any type of glass in deep sea sediments. (orig./TWO)

  8. Study of gamma ray analysis software's. Application to activation analysis of geological samples

    International Nuclear Information System (INIS)

    Silva, Luiz Roberto Nogueira da

    1998-01-01

    A comparative evaluation of the gamma-ray analysis software VISPECT, in relation to two commercial gamma-ray analysis software packages, OMNIGAM (EG and G Ortec) and SAMPO 90 (Canberra) was performed. For this evaluation, artificial gamma ray spectra were created, presenting peaks of different intensities and located at four different regions of the spectrum. Multiplet peaks with equal and different intensities, but with different channel separations, were also created. The results obtained showed a good performance of VISPECT in detecting and analysing single and multiplet peaks of different intensities in the gamma-ray spectrum. Neutron activation analysis of the geological reference material GS-N (IWG-GIT) and of the granite G-94, used in a Proficiency Testing Trial of Analytical Geochemistry Laboratories, was also performed , in order to evaluate the VISEPCT software in the analysis of real samples. The results obtained by using VISPECT were as good or better than the ones obtained using the other programs. (author)

  9. Surficial geology of Mars: A study in support of a penetrator mission to Mars

    Science.gov (United States)

    Spudis, P.; Greeley, R.

    1976-01-01

    Physiographic and surficial cover information were combined into unified surficial geology maps (30 quadrangles and 1 synoptic map). The surface of Mars is heterogeneous and is modified by wind, water, volcanism, tectonism, mass wasting and other processes. Surficial mapping identifies areas modified by these processes on a regional basis. Viking I mission results indicate that, at least in the landing site area, the surficial mapping based on Mariner data is fairly accurate. This area was mapped as a lightly cratered plain with thin or discontinuous eolian sediment. Analysis of lander images indicates that this interpretation is very close to actual surface conditions. These initial results do not imply that all surficial units are mapped correctly, but they do increase confidence in estimates based on photogeologic interpretations of orbital pictures.

  10. Active fault and other geological studies for seismic assessment: present state and problems

    Energy Technology Data Exchange (ETDEWEB)

    Kakimi, Toshihiro [Nuclear Power Engineering Corp., Tokyo (Japan)

    1997-03-01

    Evaluation system of earthquakes from an active fault is, in Japan, based on the characteristic earthquake model of a wide sense that postulates essentially the same (nearly the maximum) magnitude and recurrence interval during the recent geological times. Earthquake magnitude M is estimated by empirical relations among M, surface rupture length L, and surface fault displacement D per event of the earthquake faults on land in Japan. Recurrence interval R of faulting/earthquake is calculated from D and the long-term slip rate S of a fault as R=D/S. Grouping or segmentation of complicatedly distributed faults is an important, but difficult problem in order to distinguish a seismogenic fault unit corresponding to an individual characteristic earthquake. If the time t of the latest event is obtained, the `cautiousness` of a fault can be judged from R-t or t/R. According to this idea, several faults whose t/R exceed 0.5 have been designated as the `precaution faults` having higher probability of earthquake occurrence than the others. A part of above evaluation has been introduced at first into the seismic-safety examination system of NPPs in 1978. According to the progress of research on active faults, the weight of interest in respect to the seismic hazard assessment shifted gradually from the historic data to the fault data. Most of recent seismic hazard maps have been prepared in consideration with active faults on land in Japan. Since the occurrence of the 1995 Hyogoken-Nanbu earthquake, social attention has been concentrated upon the seismic hazard due to active faults, because this event was generated from a well-known active fault zone that had been warned as a `precaution fault`. In this paper, a few recent topics on other geological and geotechnical researches aiming at improving the seismic safety of NPPs in Japan were also introduced. (J.P.N.)

  11. Design study on containers for geological disposal of high-level radioactive waste. Phase 2

    International Nuclear Information System (INIS)

    1986-01-01

    This study has considered the feasibility of three designs for containers which would isolate the waste from the environment for a minimum period of 500 to 1000 years. The candidate container designs were taken from the results of a previous study by Ove Arup and Partners (1985) and were developed as the study progressed. Their major features can be summarized as follows: Type A: A thin-walled corrosion-resistant metal shell filled with lead or cement grout. Type B: An unfilled thick-walled carbon steel shell. Type C: an unfilled carbon steel shell plated externally with corrosion-resistant metal. Reference repository conditions in clay, granite and salt, reference disposal operations and metals corrosion data have been taken from various European Community radioactive waste management research and engineering projects. The study concludes that design types A and B are feasible in manufacturing terms but design Type C is not. Furthermore, a titanium-palladium alloy is considered the most suitable metal for Type A container shells and lead is the preferred filler. The analysis shows that design Types A and B both have adequate resistance to pressure and temperature loadings and both would resist accidental impact damage when upright. A reduction in waste heat output at disposal would lower the stress levels in Type A containers but would have virtually no effect on Type B. There is insufficient data to compare the relative costs and benefits of design Types A and B. In conclusion design Types A and B are both considered feasible but Type A would require more development than Type B. In both cases further research is needed to confirm the long-term corrosion performance of the candidate materials. It is recommended that model containers should be produced to demonstrate the proposed methods of manufacture and that they should be tested to validate the analytical techniques used

  12. Assembling of a low energy ion beam analysis facility and use of Nuclear Microprobe techniques in geological studies

    International Nuclear Information System (INIS)

    Utui, R.

    1996-11-01

    In this work, both PIXE and ion beam induced luminescence, or just Ionoluminescence (IL) were used for geochemical studies. The possibility of rapid absolute quantification of elements in the ppm level by PIXE combined with the yet higher sensitivity of IL to transition metals and Rare Earth Elements (REE) activators, in the absence of quenching phenomena, allow for a synergic use of the two methods in geological applications with enhanced sensitivity. IL and PIXE were combined for studying REE distribution in apatite minerals and ion beam induced damage in inorganic material in general with emphasis to synthetically grown zircon crystals doped with REE. Due to the sensitivity of IL to changes in chemical bonding in the material, beam damage effects can be studied even at low integrated doses, through wavelength shift or fading of the induced light. Micro PIXE technique was used for studying profile concentrations of trace elements in pyrite grains and of elements used as geothermometers. Geothermometry allowed to assess the cooling rates in iron meteorites and the mineralization conditions in metamorphic rocks, attempting to describe the tectonic history of the terranes, with application in petrologic studies and geological prospecting. 148 refs

  13. Assembling of a low energy ion beam analysis facility and use of Nuclear Microprobe techniques in geological studies

    Energy Technology Data Exchange (ETDEWEB)

    Utui, R.

    1996-11-01

    In this work, both PIXE and ion beam induced luminescence, or just Ionoluminescence (IL) were used for geochemical studies. The possibility of rapid absolute quantification of elements in the ppm level by PIXE combined with the yet higher sensitivity of IL to transition metals and Rare Earth Elements (REE) activators, in the absence of quenching phenomena, allow for a synergic use of the two methods in geological applications with enhanced sensitivity. IL and PIXE were combined for studying REE distribution in apatite minerals and ion beam induced damage in inorganic material in general with emphasis to synthetically grown zircon crystals doped with REE. Due to the sensitivity of IL to changes in chemical bonding in the material, beam damage effects can be studied even at low integrated doses, through wavelength shift or fading of the induced light. Micro PIXE technique was used for studying profile concentrations of trace elements in pyrite grains and of elements used as geothermometers. Geothermometry allowed to assess the cooling rates in iron meteorites and the mineralization conditions in metamorphic rocks, attempting to describe the tectonic history of the terranes, with application in petrologic studies and geological prospecting. 148 refs.

  14. Radiation damage studies on natural rock salt from various geological localities of interest to the radioactive waste disposal program

    International Nuclear Information System (INIS)

    Levy, P.W.

    1981-01-01

    As part of a program to investigate radiation damage in geological materials of interest to the radioactive waste disposal program, radiation damage, particularly radiation induced sodium metal colloid formation, has been studied in 14 natural rock salt samples. All measurements were made with equipment for making optical absorption and other measurements on samples, in a temperature controlled irradiation chamber, during and after 0.5 to 3.0 MeV electron irradiation. Samples were chosen for practical and scientific purposes, from localities that are potential repository sites and from different horizons at certain localities

  15. Data base dictionary for the Oak Ridge Reservation Hydrology and Geology Study Groundwater Data Base. Environmental Restoration Program

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, B.K.

    1993-04-01

    The Oak Ridge Reservation Hydrology and Geology Study (ORRHAGS) Groundwater Data Base has been compiled to consolidate groundwater data from the three US Department of Energy facilities located on the Oak Ridge Reservation: the Oak Ridge K-25 Site, the Oak Ridge National Laboratory, and the Oak Ridge Y-12 Plant. Each of these facilities maintains its own groundwater and well construction data bases. Data were extracted from the existing data bases, converted to a consistent format, and integrated into the ORRHAGS Groundwater Data Base structures. This data base dictionary describes the data contained in the ORRHAGS Groundwater Data Base and contains information on data base structure, conventions, contents, and use.

  16. Technical support for GEIS: radioactive waste isolation in geologic formations. Volume 12. Repository preconceptual design studies: shale

    International Nuclear Information System (INIS)

    1978-04-01

    This document describes a preconceptual design for a nuclear waste storage facility in shale. The facility design consists of several chambers excavated deep within a geologic formation together with access shafts and supportive surface structures. The facility design provides for: receiving and unloading waste containers; lowering them down shafts to the mine level; transporting them to the proper storage area, and emplacing them in mined storage rooms. Drawings of the facility design are contained in TM-36/13, ''Drawings for Repository Preconceptual Design Studies: Shale.''

  17. Technical support for GEIS: radioactive waste isolation in geologic formations. Volume 14. Repository preconceptual design studies: basalt

    International Nuclear Information System (INIS)

    1978-04-01

    This document describes a preconceptual design for a nuclear waste storage facility in basalt. The facility design consists of several chambers excavated deep within a geologic formation together with access shafts and supportive surface structures. The facility design provides for: receiving and unloading waste containers; lowering them down shafts to the mine level; transporting them to the proper storage area and emplacing them in mined storage rooms. Drawings of the facility design are contained in TM-36/15, ''Drawings for Repository Preconceptual Design Studies: Basalt.''

  18. Study of some physical aspects previous to design of an exponential experiment; Estudio de algunos aspectos fisicos previos al diseno de una experiencia exponencial

    Energy Technology Data Exchange (ETDEWEB)

    Caro, R.; Francisco, J. L. de

    1961-07-01

    This report presents the theoretical study of some physical aspects previous to the design of an exponential facility. The are: Fast and slow flux distribution in the multiplicative medium and in the thermal column, slowing down in the thermal column, geometrical distribution and minimum needed intensity of sources access channels and perturbations produced by possible variations in its position and intensity. (Author) 4 refs.

  19. Quantifying the influence of previously burned areas on suppression effectiveness and avoided exposure: A case study of the Las Conchas Fire

    Science.gov (United States)

    Matthew P. Thompson; Patrick Freeborn; Jon D. Rieck; Dave Calkin; Julie W. Gilbertson-Day; Mark A. Cochrane; Michael S. Hand

    2016-01-01

    We present a case study of the Las Conchas Fire (2011) to explore the role of previously burned areas (wildfires and prescribed fires) on suppression effectiveness and avoided exposure. Methodological innovations include characterisation of the joint dynamics of fire growth and suppression activities, development of a fire line effectiveness framework, and...

  20. Perturbation of lipids and glucose metabolism associated with previous 2,4-D exposure: a cross-sectional study of NHANES III data, 1988-1994

    Science.gov (United States)

    Background Results from previous population studies showed that mortality rates from acute myocardial infarction and type-2 diabetes during the 1980s and 1990s in rural, agricultural counties of Minnesota, Montana, North and South Dakota, were higher in counties with a higher le...

  1. Study of Geological Analogues for Understanding the Radar Sounder Response of the RIME Targets

    Science.gov (United States)

    Thakur, S.; Bruzzone, L.

    2017-12-01

    Radar for Icy Moon Exploration (RIME), the radar sounder onboard the Jupiter Icy Moons Explorer (JUICE), is aimed at characterizing the ice shells of the Jovian moons - Ganymede, Europa and Callisto. RIME is optimized to operate at 9 MHz central frequency with bandwidth of 1 MHz and 2.7 MHz to achieve a penetration depth up to 9 km through ice. We have developed an approach to the definition of a database of simulated RIME radargrams by leveraging the data available from airborne and orbital radar sounder acquisitions over geological analogues of the expected icy moon features. These simulated radargrams are obtained by merging real radar sounder data with models of the subsurface of the Jupiter icy moons. They will be useful for geological interpretation of the RIME radargrams and for better predicting the performance of RIME. The database will also be useful in developing pre-processing and automatic feature extraction algorithms to support data analysis during the mission phase of RIME. Prior to the JUICE mission exploring the Jovian satellites with RIME, there exist radar sounders such as SHARAD (onboard MRO) and MARSIS (onboard MEX) probing Mars, the LRS (onboard SELENE) probing the Moon, and many airborne sounders probing the polar regions of Earth. Analogues have been identified in these places based on similarity in geo-morphological expression. Moreover, other analogues have been identified on the Earth for possible dedicated acquisition campaigns before the RIME operations. By assuming that the subsurface structure of the RIME targets is approximately represented in the analogue radargrams, the difference in composition is accounted for by imposing different dielectric and subsurface attenuation models. The RIME radargrams are simulated from the analogue radargrams using the radar equation and the RIME processing chain and accounting for different possible scenarios in terms of subsurface structure, dielectric properties and instrument parameters. For

  2. A cross-sectional study of tuberculosis drug resistance among previously treated patients in a tertiary hospital in Accra, Ghana: public health implications of standardized regimens.

    Science.gov (United States)

    Forson, Audrey; Kwara, Awewura; Kudzawu, Samuel; Omari, Michael; Otu, Jacob; Gehre, Florian; de Jong, Bouke; Antonio, Martin

    2018-04-02

    Mycobacterium tuberculosis drug resistance is a major challenge to the use of standardized regimens for tuberculosis (TB) therapy, especially among previously treated patients. We aimed to investigate the frequency and pattern of drug resistance among previously treated patients with smear-positive pulmonary tuberculosis at the Korle-Bu Teaching Hospital Chest Clinic, Accra. This was a cross-sectional survey of mycobacterial isolates from previously treated patients referred to the Chest Clinic Laboratory between October 2010 and October 2013. The Bactec MGIT 960 system for mycobactrerial culture and drug sensitivity testing (DST) was used for sputum culture of AFB smear-positive patients with relapse, treatment failure, failure of smear conversion, or default. Descriptive statistics were used to summarize patient characteristics, and frequency and patterns of drug resistance. A total of 112 isolates were studied out of 155 from previously treated patients. Twenty contaminated (12.9%) and 23 non-viable isolates (14.8%) were excluded. Of the 112 studied isolates, 53 (47.3%) were pan-sensitive to all first-line drugs tested Any resistance (mono and poly resistance) to isoniazid was found in 44 isolates (39.3%) and any resistance to streptomycin in 43 (38.4%). Thirty-one (27.7%) were MDR-TB. Eleven (35.5%) out of 31 MDR-TB isolates were pre-XDR. MDR-TB isolates were more likely than non-MDR isolates to have streptomycin and ethambutol resistance. The main findings of this study were the high prevalence of MDR-TB and streptomycin resistance among previously treated TB patients, as well as a high prevalence of pre-XDR-TB among the MDR-TB patients, which suggest that first-line and second-line DST is essential to aid the design of effective regimens for these groups of patients in Ghana.

  3. Preliminary geological study in kabupaten Pamekasan area to support the selection of candidate site of nuclear desalination plant

    International Nuclear Information System (INIS)

    Ngadenin; Lilik Subiantoro; Kurnia Setiawan Widana

    2014-01-01

    The area around the southern coast Pamekasan is one of the candidates for the alternatives location of nuclear desalination plant site. In 1949 around Sampang Madura ever tectonic earthquake measuring 5 on the Richter scale with its epicenter on land. Tectonic earthquake with epicenter on land is likely related to the presence of active faults on the Madura island. Location prospective nuclear desalination plant site should be away or free of active faults. The study aimed to obtain geological information and find out the characteristics of tectonics including active fault to support site studies of nuclear desalination plant on the island of Madura. The method used is the geological mapping scale, 1 : 50,000. Lithology in the area along the south coast district Pamekasan is alluvium Holocene age and conglomerate units of Pleistocene age. There were no indications of active faults in the region. Candidates site at this location is less attractive in terms of geotechnical foundation as can be ascertained bedrock will be found sufficient in that building construction will require expensive. (author)

  4. Numerical Verification Of Geotechnical Structure In Unfavourable Geological Conditions – Case Study

    Directory of Open Access Journals (Sweden)

    Drusa Marián

    2015-06-01

    Full Text Available Numerical modelling represents a powerful tool not only for special geotechnical calculations in cases of complicated and difficult structure design or their foundation conditions, but also for regular tasks of structure foundation. Finite element method is the most utilized method of numerical modelling. This method was used for calculations of the retaining wall monitored during 5 years after construction. Retaining wall of the parking lot with the facing from gabion blocks was chosen for numerical model. Besides the unfavourable geological conditions, a soft nature of the facing was also a difficult part of the modelling. This paper presents the results of the modelling when exact geometry, material characteristics and construction stages were simulated. The results capture the trend of displacements even though the basic material models were utilized. The modelling proved the ability of the finite element method to model the retaining structure with sufficient accuracy as well as reasonable demand on quality and quantity of input data. This method can then be used as a regular design tool during project preparation.

  5. Consolidation of geologic studies of geopressured-geothermal resources in Texas. 1990 Annual report

    Energy Technology Data Exchange (ETDEWEB)

    Raney, J.A.; Seni, S.J.; DuBar, J.R.; Walter, T.G.

    1991-03-01

    In a five-county area of South Texas, geopressured-geothermal reservoirs in the upper Wilcox Group colocated with heavy-oil reservoirs in the overlying Jackson Group. In 1990, research at the Bureau of Economic Geology concentrated on evaluating the potential of using geopressured-geothermal water for hot-water flooding of heavy-oil reservoirs. Favorable geothermal reservoirs are defined by thick deltaic sandstones and growth-fault-bounded compartments. Potential geothermal reservoirs are present at a depth of 11,000 ft (3,350 m) to 15,000 ft (4,570 m) and contain water at temperatures of 350 F (177 C) to 383 F (195 C) in Fandango field, Zapata County. One potential geothermal reservoir sandstone in the upper Wilcox (R sandstone) is composed of a continuous sand body 100 ft (30 m) to greater than 200 ft (>61 m) thick. Fault blocks average 2 to 4 mi{sup 2} (5.2 to 10.4 km{sup 2}) in area.

  6. The polar layered deposits on Mars: Inference from thermal inertia modeling and geologic studies

    Science.gov (United States)

    Herkenhoff, K. E.

    1992-01-01

    It is widely believed that the Martian polar layered deposits record climate variations over at least the last 10 to 100 m.y., but the details of the processes involved and their relative roles in layer formation and evolution remain obscure. Weathering of the Martian layered deposits by sublimation of water ice can account for the thermal inertias, water vapor abundances, and geologic relationships observed in the Martian polar regions. The nonvolatile components of the layered deposits appears to consist mainly of bright red dust, with small amounts of dark dust. Dark dust, perhaps similar to the magnetic material found at the Viking Lander sites, may preferentially form filamentary residue particles upon weathering of the deposits. Once eroded, these particles may saltate to form the dark dunes found in both polar regions. This scenario for the origin and evolution of the dark material within the polar layered deposits is consistent with the available imaging and thermal data. Further experimental measurements of the thermophysical properties of magnetite and maghemite under Martian conditions are needed to better test this hypothesis.

  7. A geological reconnaissance study of the Dyfi Valley region, Gwynedd/Powys, Wales

    International Nuclear Information System (INIS)

    Martin, B.A.; Howells, M.F.; Reedman, A.J.

    1981-01-01

    A collation of existing maps and data backed up by localised checking, reinterpretation and modification, employing sampling, structural measurements and aerial photograph interpretation, have updated the geological information available on the Dyfi Valley region. The region comprises an argillaceous-dominated Ordovician and Silurian sedimentary pile of approximately 4 km thickness. Thick formations of mudstones and silty mudstones with thin intercalations of silty sandstone and fine-grained sandstone predominate and exhibit fewer variations in thickness and extent than the subordinate formations with a higher proportion of sand-grade material. Three periods of deformation (D 1 -D 3 ) are distinguished, with the D 1 phase dominating the structure of the region by forming upright, asymmetrical, large (km) scale folds (F 1 ) of a NNE-SSW to NE-SW trend and producing an almost ubiquitous slaty cleavage (S 1 ). The succeeding deformations produced localised crenulation cleavages, kink bands and box folds. Data on the faulting and jointing associated with this deformation history are also presented. (author)

  8. Prediction Study of Tunnel Collapse Risk in Advance based on Efficacy Coefficient Method and Geological Forecast

    Directory of Open Access Journals (Sweden)

    QIU Daohong

    2014-08-01

    Full Text Available Collapse is one of the most common accidents in underground constructions. Risk evaluation is the method of measuring the risk of chamber collapse. To ensure the safety of construction, a risk evaluation model of tunnel collapse based on an efficacy coefficient method and geological prediction was put forward. Based on the comprehensive analysis of collapse factors, five main factors including rock uniaxial compressive strength, surrounding rock integrated coefficient, state of discontinuous structural planes, the angle between tunnel axis and major structural plane and underground water were chosen as the risk evaluation indices of tunnel collapse. The evaluation indices were quantitatively described by using TSP203 system and core-drilling to establish the risk early warning model of tunnel collapse based on the basic principle of the efficacy coefficient method. The model established in this research was applied in the collapse risk recognition of Kiaochow Bay subsea tunnel in Qingdao, China. The results showed that the collapse risk recognition method presents higher prediction accuracy and provided a new idea for the risk prediction of tunnel collapse.

  9. A preliminary study on the geochemical environment for deep geological disposal of high level radioactive waste in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chun Soo; Bae, Dae Seok; Kim, Kyung Su; Koh, Yong Kwon; Park, Byoung Yun

    2000-03-01

    Geochemical study on the groundwater from crystalline rocks (granite and gneiss) for the deep geological disposal of high-level radioactive waste was carried out in order to elucidate the hydrogeochemical and isotope characteristics and geochemical evolution of the groundwater. Study areas are Jungwon, Chojeong, Youngcheon and Yusung for granite region, Cheongyang for gneiss region, and Yeosu for volcanic region. Groundwaters of each study areas weree sampled and analysed systematically. Groundwaters can be grouped by their chemistry and host rock. Origin of the groundwater was proposed by isotope ({sup 18}O, {sup 2}H, {sup 13}C, {sup 34}S, {sup 87}Sr, {sup 15}N) studies and the age of groundwater was inferred from their tritium contents. Based ont the geochemical and isotope characteristics, the geochemical evolutions of each types of groundwater were simulated using SOLVEQ/CHILLER and PHREEQC programs.

  10. Metallogeny of Mesoproterozoic Sedimentary Rocks in Idaho and Montana - Studies by the Mineral Resources Program, U.S. Geological Survey, 2004-2007

    Science.gov (United States)

    O'Neill, J. Michael

    2007-01-01

    -central Idaho are integrated and summarized by Bookstrom and others (chapter B, this volume). In particular, their field investigations and analysis of evidence and previous arguments for synsedimentary versus epigenetic mineral deposit types, both of which have been postulated by earlier workers, led them to conclude that both processes were likely instrumental in forming the ore deposits of the Blackbird district. Finally, this report supplies new data on isotopic ratios of sulfur, oxygen, carbon, and helium in minerals associated with cobalt-bearing ores of the cobalt belt. Slack (chapter C, this volume) identified several previously unrecognized rare-earth-element minerals in Blackbird ores: monazite (Ce,La,Y,Th)PO4, xenotime (YPO4), allanite (CaCe)2(Al,Fe)3Si3O12(OH), and gadolinite (Be2FeY2Si2O10). Light rare-earth elements reside mostly in monazite, whereas yttrium and heavy rare-earth minerals reside mostly in xenotime. Dated monazite, which in the Blackbird district is interstitial to cobaltite, is Cretaceous. This date brings into question the otherwise geologically convincing interpretation of Blackbird ores as being of Mesoproterozoic age and synsedimentary origin. This volume consists of three summary articles: A. Great Divide megashear, Montana, Idaho, and Washington: An intraplate crustal-scale shear zone recurrently active since the Mesoproterozoic by J. Michael O'Neill, Edward T. Ruppel, and David A. Lopez B. Blackbird Fe-Cu-Co-Au-REE deposits by Arthur A. Bookstrom, Craig A. Johnson, Gary P. Landis, and Thomas P. Frost C. Geochemical and mineralogical studies of sulfide and iron oxide deposits in the Idaho cobalt belt by John F. Slack

  11. Experimental methodology to study radionuclide sorption and migration in geological formations and engineered barriers of waste repositories

    International Nuclear Information System (INIS)

    Rojo Sanz, H.

    2010-01-01

    In Spain, the waste management options include either the possibility of a final storage in a deep geological repository (DGR) or the centralized temporal surface disposal (CTS). DGRs are based in a multi-barrier concept with the geological barrier and including the vitrified waste, the metal containers and engineered barriers such as compacted bentonite and cement-based materials. On the other hand, CTS mainly considers concrete and cement to confine the metal canisters containing the waste. Radionuclide migration will mainly take place by the existence of chemical concentration gradients being thus diffusion the main transport mechanism or by the existence of hydraulic gradients due to the existence of water-conductive fractures. Radionuclide sorption/retention on the materials composing the natural and engineered barriers is the fundamental process controlling contaminant migration. The evaluation of sorption parameters and the understanding of the different mechanisms leading to radionuclide retention are very important issues. The study of diffusion processes is very relevant as well. This paper describes the main experimental methodologies applied to analyse radionuclide transport in the different barriers of radioactive repositories. Particularly we focused on obtaining of retention parameters as distribution coefficients, kd, or retardation factors, Rf, and diffusion coefficients of radionuclides. (Author) 6 refs.

  12. Integrated geophysical survey for the geological structural and hydrogeothermal study of the North-western Gargano promontory (Southern Italy

    Directory of Open Access Journals (Sweden)

    D. Schiavone

    1996-06-01

    Full Text Available A multimethodological geophysical survey was performed in the north-western part of the Gargano promontory to study the geological structural setting and the underground fluid flow characteristics. The area has a complex tectonics with some magmatic outcrops and shallow low-enthalpy waters. Electrical, seismic reflection, gravimetric and magnetic surveys were carried out to reconstruct the geological structures; and in order to delineate the hydrogeothermal characteristics of the area, the self-potential survey was mainly used. Moreover magnetic and self-potential measurements were also performed in the Lesina lake. The joint three-dimensional interpretation of the geophysical data disclosed a large horst and graben structure covering a large part of the area. In the central part of the horst a large ramified volcanic body was modelled. The models show some intrusions rising from it to or near to the surface. The main structures are well deep-seated in the Crust and along them deep warm fluids rise as the SP data interpretation indicates.

  13. Strategic Petroleum Reserve (SPR) additional geologic site characterization studies, Bayou Choctaw salt dome, Louisiana

    Energy Technology Data Exchange (ETDEWEB)

    Neal, J.T. [Sandia National Labs., Albuquerque, NM (United States); Magorian, T.R. [Magorian (Thomas R.), Amherst, NY (United States); Byrne, K.O.; Denzler, S. [Acres International Corp., Amherst, NY (United States)

    1993-09-01

    This report revises and updates the geologic site characterization report that was published in 1980. Revised structure maps and sections show interpretative differences in the dome shape and caprock structural contours, especially a major east-west trending shear zone, not mapped in the 1980 report. Excessive gas influx in Caverns 18 and 20 may be associated with this shear zone. Subsidence values at Bayou Choctaw are among the lowest in the SPR system, averaging only about 10 mm/yr but measurement and interpretation issues persist, as observed values often approximate measurement accuracy. Periodic, temporary flooding is a continuing concern because of the low site elevation (less than 10 ft), and this may intensify as future subsidence lowers the surface even further. Cavern 4 was re-sonared in 1992 and the profiles suggest that significant change has not occurred since 1980, thereby reducing the uncertainty of possible overburden collapse -- as occurred at Cavern 7 in 1954. Other potential integrity issues persist, such as the proximity of Cavern 20 to the dome edge, and the narrow web separating Caverns 15 and 17. Injection wells have been used for the disposal of brine but have been only marginally effective thus far; recompletions into more permeable lower Pleistocene gravels may be a practical way of increasing injection capacity and brinefield efficiency. Cavern storage space is limited on this already crowded dome, but 15 MMBBL could be gained by enlarging Cavern 19 and by constructing a new cavern beneath and slightly north of abandoned Cavern 13. Environmental issues center on the low site elevation: the backswamp environment combined with the potential for periodic flooding create conditions that will require continuing surveillance.

  14. The impact of smoking and previous periodontal disease on peri-implant microbiota and health: a retrospective study up to 7-year follow-up.

    Science.gov (United States)

    Quaranta, Alessandro; Assenza, Bartolomeo; D'Isidoro, Orlando; Profili, Fabia; Polimeni, Antonella; Vozza, Iole

    2015-01-01

    To evaluate the impact of smoking and previous periodontal disease on peri-implant microbiota and health in medium to long-term maintained patients. A retrospective evaluation of partial edentulous patients restored with dental implants and enrolled in a regular supportive therapy was performed. Inclusion criteria were: medium to long-term periodontal and implant maintenance (at least 5 years), a minimum of 2 implants placed in each patient, absence of systemic diseases that may affect osseointegration. 30 implants in 15 patients were included in the study. Subjects were divided in smokers or non-smokers and between patients previously affected by periodontal disease and periodontally healthy. Peri-implant and periodontal parameters were assessed (PD,BoP, mPI). Microbiological samples were collected around implant and an adjacent tooth. Real- Time Polymerase Chain Reaction (RT-PCR) analysis was performed. In all the three groups no differences in bacterial counts between dental and implant sites were observed. Non smoker, healthy patients: healthy clinical parameters, significant counts of spirochetes in isolated patients. Non smokers with previous periodontal disease: occasional positive BoP values, significant high counts of pathogenic bacteria. Smokers with previous periodontal disease: clinical signs of inflammation including deep pockets and slight bone resorption, significant counts of pathogenic bacteria. Over a follow-up of 5 to 7 years, it is possible to state that the absence of smoking habit and previous periodontal disease positively influences the peri-implant microbiological and clinical conditions in partial edentulous patients restored with dental implants and enrolled in a strict regular supportive therapy.

  15. Geological study on the metal flux and ore deposit formation in the ocean

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Se-Won; Lee, Sung-Rock; Choi, Hun-Soo [Korea Institute of Geology Mining and Materials, Taejon (KR)] (and others)

    1999-12-01

    The resource potential of the Mn-crusts is increasing by the growth of the world cobalt demand. Platinum and phosphate are also assumed to be recovered as well as cobalt, nickel, copper, and ferromanganese. The behaviour of the platinum group elements and the rare earth elements in the Mn-crust were reported in the previous studies, but the characteristics of the other rare elements were still not known in detail. Major, minor, and trace elements of the characteristic and representative 40 Mn-crust samples in the Pacific, Atlantic. and Indian Ocean were analyzed. Mn-crusts can be divided into three genetic types, such as, hydrogenetic type, hydrothermal type, and hydrothermal-hydrogenetic type. Te, Mo, Tl, Sb, Bi and etc. were enriched in general. And it is considered that such elements could be by-products in die Mn-crusts as well as economically important elements, such as Co, Ni, Mn, and Pt. The variation according to the genetic types and locations was observed. The chemical compositions of the each genetic type were also analyzed by the method of the Q-mode factor analysis. One objective of the Research voyage SAA3 (TAN 9909) was to conduct sea floor sampling and camera towing along the transacts across the known flow path of the Deep Western Boundary Current (DWBC) perpendicular to the lowermost margin of the Campbell Plateau and Bollons Seamount, primarily to collect Mn nodules. During the cruise, two successful camera and dredge transacts were completed. The first transect was located at the southern end of Leg 1 traversing the abyssal plain from the flank of Campbell Plateau through flow associated with the Antarctic Circumpolar Current and the overlying Subantarctic Front (SAF). The second was located at the northern end of Leg 2 traversing towards Bounty Platform through flow associated with the DWBC and the overlying SAF. As a result, from the 12 successful dredges, over 4000 manganese nodules, ranging in size from <2-40 cm, and cumulatively weighing

  16. Hydrogeological Properties of Geological Elements in Geological Model around KURT

    International Nuclear Information System (INIS)

    Park, Kyung Woo; Kim, Kyung Soo; Koh, Yong Kwon; Choi, Jong Won

    2012-01-01

    To develop site characterization technologies for a radioactive waste disposal research in KAERI, the geological and hydrogeological investigations have been carried out since 1997. In 2006, the KURT (KAERI Underground Research Tunnel) was constructed to study a solute migration, a microbiology and an engineered barrier system as well as deeply to understand geological environments in in-situ condition. This study is performed as one of the site characterization works around KURT. Several investigations such as a lineament analysis, a borehole/tunnel survey, a geophyscial survey and logging in borehole, were used to construct the geological model. As a result, the geological model is constructed, which includes the lithological model and geo-structural model in this study. Moreover, from the results of the in-situ hydraulic tests, the hydrogeological properties of elements in geological model were evaluated.

  17. Geological Corrections in Gravimetry

    Science.gov (United States)

    Mikuška, J.; Marušiak, I.

    2015-12-01

    Applying corrections for the known geology to gravity data can be traced back into the first quarter of the 20th century. Later on, mostly in areas with sedimentary cover, at local and regional scales, the correction known as gravity stripping has been in use since the mid 1960s, provided that there was enough geological information. Stripping at regional to global scales became possible after releasing the CRUST 2.0 and later CRUST 1.0 models in the years 2000 and 2013, respectively. Especially the later model provides quite a new view on the relevant geometries and on the topographic and crustal densities as well as on the crust/mantle density contrast. Thus, the isostatic corrections, which have been often used in the past, can now be replaced by procedures working with an independent information interpreted primarily from seismic studies. We have developed software for performing geological corrections in space domain, based on a-priori geometry and density grids which can be of either rectangular or spherical/ellipsoidal types with cells of the shapes of rectangles, tesseroids or triangles. It enables us to calculate the required gravitational effects not only in the form of surface maps or profiles but, for instance, also along vertical lines, which can shed some additional light on the nature of the geological correction. The software can work at a variety of scales and considers the input information to an optional distance from the calculation point up to the antipodes. Our main objective is to treat geological correction as an alternative to accounting for the topography with varying densities since the bottoms of the topographic masses, namely the geoid or ellipsoid, generally do not represent geological boundaries. As well we would like to call attention to the possible distortions of the corrected gravity anomalies. This work was supported by the Slovak Research and Development Agency under the contract APVV-0827-12.

  18. Old Geology and New Geology

    Science.gov (United States)

    2003-01-01

    [figure removed for brevity, see original site] Released 28 May 2003Mangala Vallis one of the large outflow channels that channeled large quantities of water into the northern lowlands, long ago on geological timescales. This valley is one of the few in the southern hemisphere, as well as one of the few west of the Tharsis bulge. A closer look at the channel shows more recent weathering of the old water channel: the walls of the channel show small, dark slope streaks that form in dusty areas; and much of the surrounding terrain has subtle linear markings trending from the upper left to the lower right, which are probably features sculpted and streamlined by the wind. Geology still shapes the surface of Mars today, but its methods over the eons have changed.Image information: VIS instrument. Latitude -6, Longitude 209.6 East (150.4 West). 19 meter/pixel resolution.Note: this THEMIS visual image has not been radiometrically nor geometrically calibrated for this preliminary release. An empirical correction has been performed to remove instrumental effects. A linear shift has been applied in the cross-track and down-track direction to approximate spacecraft and planetary motion. Fully calibrated and geometrically projected images will be released through the Planetary Data System in accordance with Project policies at a later time.NASA's Jet Propulsion Laboratory manages the 2001 Mars Odyssey mission for NASA's Office of Space Science, Washington, D.C. The Thermal Emission Imaging System (THEMIS) was developed by Arizona State University, Tempe, in collaboration with Raytheon Santa Barbara Remote Sensing. The THEMIS investigation is led by Dr. Philip Christensen at Arizona State University. Lockheed Martin Astronautics, Denver, is the prime contractor for the Odyssey project, and developed and built the orbiter. Mission operations are conducted jointly from Lockheed Martin and from JPL, a division of the California Institute of Technology in Pasadena.

  19. Study on the interaction mechanism between the special geological environment and their extreme geo-microbes in Dagang Oilfield by combined methods

    Science.gov (United States)

    Yao, Jun

    2010-05-01

    Geo-microbes and their function were widespread ever since life appeared on the earth. Geo-microbiological process has left a rich and colorful material record in the geological body of earth, the most critical record of which is all sorts of organic hieroglyph and various forms of organic matter derived from bio-organisms, and oil field is the most ideal geological location to preserve these organic matters. It have already produced or might produce petroleum and natural gas sedimentary rocks under natural conditions, also known as olefiant (gas) rock or the parent rock, which is the product of the interaction between the life-system and earth environmental system in the specific geological conditions and integrate the whole microbial ecosystem in the geological time. The microbial community under extreme geological environment of Dagang Oilfield is relatively simple, therefore it is quite easy to investigate the special relationship between geo-microbes and biogeochemistry. We have mastered a large number of information related with the geological condition and biological species of Dagang Oilfield; what's more we also have isolated a number of archimycetes strains with different extremophiles capacity from the core samples collected in the Dagang oil field. At present, we are to proceed with the cooperative research at Environment School of Yale University and Institute of the Earth's biosphere using these strains. In the future, we will work together to carry out geological surveys in the field using international first-class equipment and methods and study the geological environment of Dagang Oilfield utilizing isotope techniques and mineral phase analysis method. Meanwhile we are going to undertake the on-line monitoring of the overall microbial activity of these collected geological samples, the specific metabolic activity of these extreme strains of microorganisms and the biomarkers produced during their metabolic processes under laboratory conditions

  20. Mortality and cardiovascular risk associated with different insulin secretagogues compared with metformin in type 2 diabetes, with or without a previous myocardial infarction: a nationwide study

    DEFF Research Database (Denmark)

    Schramm, Tina Ken; Gislason, Gunnar Hilmar; Vaag, Allan

    2011-01-01

    Aims The impact of insulin secretagogues (ISs) on long-term major clinical outcomes in type 2 diabetes remains unclear. We examined mortality and cardiovascular risk associated with all available ISs compared with metformin in a nationwide study. Methods and results All Danish residents >20 years......, initiating single-agent ISs or metformin between 1997 and 2006 were followed for up to 9 years (median 3.3 years) by individual-level linkage of nationwide registers. All-cause mortality, cardiovascular mortality, and the composite of myocardial infarction (MI), stroke, and cardiovascular mortality...... associated with individual ISs were investigated in patients with or without previous MI by multivariable Cox proportional-hazard analyses including propensity analyses. A total of 107 806 subjects were included, of whom 9607 had previous MI. Compared with metformin, glimepiride (hazard ratios and 95...

  1. A preliminary study on the long-term geologic stability for deep geological disposal of high level radioactive waste in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chun Soo; Bae, Dae Seok; Kim, Kyung Su; Park, Byoung Yoon; Koh, Young Kown [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2000-03-01

    Geology of the Korean peninsula could be grouped by 7 rock types such as plutonic rocks, crystalline gneisses, metasedimentary rocks, Paleozoic and Mesozoic sedimentary rocks, porous and massive volcanic rocks. The plutonic rock type is the largest rock groups occupying about 35.2% over the peninsula. Tectonic movement could be classified as four great stages as Precambrian, Songnim, Daebo and Bulkuksa even though the ambiguous of prior Songnim. It would be supposed to deep relationship between tectonic movement, orogeny and magmatism. And also, the magmatism within the peninsula could be divided into 5 stages such as 1st stage of Precambrian(>570Ma), 2nd stage of late Paleozoic(>250Ma), 3rd stage of early to mid Mesozoic(200-300Ma), 4th stage of late Mesozoic(135-60Ma) and 5th stage of post early Tertiary(50Ma>). In the seismicities, the peninsula has some characteristics that of the intra-plate seismic characteristics located at south eastern part of the Eurasian plate apart from the boundary of the Pacific and Philippine plate. Eurasian plate is under the two stress direction acting eastward stresses induced the collision of Indo- Australlian plate and westward stresses due to the subduction of due the Pacific and Philippine plate. For the purpose of the quantitative analysis for the safety assessment of HLW disposal, it would be desired to have the long range approach concept for the characterization of FEPs such as upper stated including climate, sae level change, uplift and subsidence, erosion and sedimentation. 38 refs., 18 figs., 25 tabs. (Author)

  2. R and D program concerning radioactive waste disposal in deep geologic formation (Study of an argilaceous formation in Belgium)

    International Nuclear Information System (INIS)

    1982-01-01

    In 1974 it was decided to start up research with a view to safe disposal of conditioned waste in geological formations in Belgium. A first R and D programme was set up for study of the Boom clay in the Mol region. Multiple research projects have been undertaken; both experimental research in the field and in the laboratory and theoretical studies. Different exploratory drillings for geohydrological and geotechnical research were performed at the potential site. Teledetection and seismic prospection campaigns have provided data on the dimensions of the argillaceous layer and on the absence of major faults. Clay samples collected during drilling campaigns have been submitted to a number of analyses in laboratory as well as analyses of possible interactions between the clay and the conditioned waste to be stored. Some of these laboratory analyses, in particular, those concerning heat transfer and corrosion have been completed by more representative experiments in a clay pit. Various mathematical models have been developed and adapted with a view to better understanding of physical and physico-chemical phenomena like heat transfer, migration and retardation of radionuclides. A feasibility study was performed. Concerning safety analyses, a probabilistic study was undertaken on the behaviour of the geological barrier. The fault tree analysis technique was applied and the study was carried out in close collaboration with the Joint Rsearch Centre in Ispra. The underground experimental room at about 220 m depth was not yet relised but the technico-economical dossier has made such progress that the excavation can start in the very beginning of the next five-year programme

  3. Geology and bedrock engineering

    International Nuclear Information System (INIS)

    1985-11-01

    This book deals with geology of Korea which includes summary, geology in central part and southern part in Korea and characteristic of geology structure, limestone like geology property of limestone, engineered property of limestone, and design and construction case in limestone area. It also introduces engineered property of the cenozoic, clay rock and shale, geologic and engineered property of phyllite and stratum.

  4. A state geological survey commitment to environmental geology - the Texas Bureau of Economic Geology

    International Nuclear Information System (INIS)

    Wermund, E.G.

    1990-01-01

    In several Texas environmental laws, the Bureau of Economic Geology is designated as a planning participant and review agency in the process of fulfilling environmental laws. Two examples are legislation on reclamation of surface mines and regulation of processing low level radioactive wastes. Also, the Bureau is the principal geological reviewer of all Environmental Assessments and Environmental Impact Statements which the Office of the Governor circulates for state review on all major developmental activities in Texas. The BEG continues its strong interest in environmental geology. In February 1988, it recommitted its Land Resources Laboratory, initiated in 1974, toward fulfilling needs of state, county, and city governments for consultation and research on environmental geologic problems. An editorial from another state geological survey would resemble the about description of texas work in environmental geology. State geological surveys have led federal agencies into many developments of environmental geology, complemented federal efforts in their evolution, and continued a strong commitment to the maintenance of a quality environment through innovative geologic studies

  5. California Geological Survey Geologic Map Index

    Data.gov (United States)

    California Natural Resource Agency — All the individual maps from the Geologic Atlas of California and the Regional Geologic map series have been georeferenced for display in a GIS (and viewable online...

  6. California Geological Survey Geologic Map Index

    Data.gov (United States)

    California Department of Resources — All the individual maps from the Geologic Atlas of California and the Regional Geologic map series have been georeferenced for display in a GIS (and viewable online...

  7. Risk for high depressive symptoms in diagnosed and previously undetected diabetes: 5-year follow-up results of the Heinz Nixdorf Recall study.

    Directory of Open Access Journals (Sweden)

    Andrea Icks

    Full Text Available OBJECTIVE: The objective of this study was to determine the risk for the development of high depressive symptoms in study participants with diagnosed and previously undetected diabetes mellitus compared to those without diabetes in a prospective population-based cohort study in Germany. METHODS: We estimated the 5-year cumulative incidence of high depressive symptoms in participants without high depressive symptoms at baseline (n = 3,633, 51.4% men, mean age (SD 59.1 (7.6 years, 7.0% diagnosed diabetes, 5.3% previously undetected diabetes from the population-based Heinz Nixdorf Recall study. Diabetes was assessed by self-report, medication, and blood glucose. High depressive symptoms were assessed using CES-D. We calculated odds ratios and their corresponding 95% confidence interval, using multiple logistic regression analyses. RESULT: Cumulative 5-year incidences (95% CI of high depressive symptoms in participants with diagnosed, undetected, and without diabetes were 7.1 (4.2-10.9, 4.1 (1.8-8.0, and 6.5 (5.6-7.4, respectively. The age-sex-adjusted OR for developing high depressive symptoms was 1.22 (0.74-2.03 in participants with diagnosed compared to those without diabetes, and 1.00 (0.59-1.68 after adjustment for BMI, physical activity, education, stroke, and myocardial infarction. The age-sex adjusted OR for developing high depressive symptoms in participants with previously undetected diabetes compared to those without diabetes was 0.72; 0.35-1.48; and fully adjusted 0.62; 0.30-1.30. CONCLUSION: We found no significant associations, maybe due to low power. However, our results are in line with a recent meta-analysis suggesting that risk of developing high depressive symptoms in patients with diagnosed diabetes may be moderately higher than in those without diabetes, and that comorbidity may explain in part this association. In participants with previously undetected diabetes, this first longitudinal study indicates that the risk is not

  8. New developments in measurement technology relevant to the studies of deep geological repositories in domed salt and basalt

    International Nuclear Information System (INIS)

    Ramirez, A.L.; Mao, N.H.

    1980-01-01

    This report briefly describes recent geophysical and geotechnical instrumentation developments relevant to the studies of deep geologic repositories. Special emphasis has been placed on techniques that appear to minimize measurement problems associated with repositories constructed in basalt or domed salt. Included in the listing are existing measurement capabilities and deficiencies that have been identified by a few authors and instrumentation workshops that have assessed the capabilities of existing instrumentation with respect to repository applications. These deficiencies have been compared with the reported advantages and limitations of the new developments described. Based on these comparisons, areas that merit further research and development have been identified. The report is based on a thorough literature review and on discussions with several instrumentation specialists involved in instrumentation development

  9. Comparison of time until elective intestinal resection regarding previous anti-tumor necrosis factor exposure: a Brazilian study on patients with Crohn's disease

    Directory of Open Access Journals (Sweden)

    Paulo Gustavo Kotze

    2018-01-01

    Full Text Available Background/Aims: The use of anti-tumor necrosis factor (anti-TNF agents seems to reduce surgical rates and delay surgical procedures in prospective trials and population-based studies in the management of Crohn's disease (CD. This study aimed to identify whether preoperative anti-TNF agents influence the time from diagnosis to surgery. Methods: An observational retrospective cohort study was conducted on patients with CD submitted to intestinal resections due to complications or medical therapy failure in a period of 7 years. The patients were allocated into 2 groups according to their previous exposure to anti-TNF agents in the preoperative period. Epidemiological aspects regarding age at diagnosis, smoking, perianal disease, and preoperative conventional therapy were considered. A Kaplan-Meier survival analysis was used to outline possible differences between the groups regarding the time to surgery. Results: A total of 123 patients were included (71 and 52 with and without previous exposure to biologics, respectively. The overall time to surgery was 108±6.9 months (maximum, 276 months. The survival estimation revealed no difference in the mean time to intestinal resection between the groups (99.78±10.62 months in the patients without and 114.01±9.07 months in those with previous anti-TNF use (log-rank P=0.35. There was no significant difference in the time to surgery regarding perianal CD (P=0.49, smoking (P=0.63, preoperative azathioprine (P=0.073 and steroid use (P=0.58. Conclusions: The time from diagnosis to surgery was not influenced by the preoperative use of anti-TNF therapy in this cohort of patients.

  10. A geological-acoustical framework for an integrated environmental evaluation in Mediterranean marine protected areas. Marettimo Island, a case study

    Science.gov (United States)

    Agate, M.; Catalano, R.; Chemello, R.; Lo Iacono, C.; Riggio, S.

    2003-04-01

    A GEOLOGICAL-ACOUSTICAL FRAMEWORK FOR AN INTEGRATED ENVIRONMENTAL EVALUATION IN MEDITERRANEAN MARINE PROTECTED AREAS. MARETTIMO ISLAND, A CASE STUDY. M. Agate (1), R. Catalano (1), R. Chemello (2), C. Lo Iacono (1) &S. Riggio (2) (1)Dipartimento di Geologia e Geodesia dell'Università di Palermo, via Archirafi 26, 90123 Palermo, clageo@katamail.com, rcatal@unipa.it (2)Dipartimento di Biologia animale dell'Università di Palermo, via Archirafi 18, 90123 Palermo,rchemello@unipa.it New analytical methods have been designed to support an objective quantitative evaluation of geological components whose results dictate the lines for a sustainable use of the natural resources. We tried to adopt the fundaments of the seascape concept, based on the thematic elements of landscape ecology and translated into terms fitting with the principles of coastal ecology. The seascape concept is central to our view of the environment and is referred to as an integrated unit (Environmental Unit) resulting from a long multidisciplinary approach, carried out in both the field and the laboratory by an interdisciplinary team of experts. Side Scan Sonar and Multi Beam acoustical data collected in the Marettimo and Ustica Islands (south-western Tyrrhenian Sea))inner shelves, make possible to sketch geomorphological and sedimentological maps, whose details have been tested as deep as 45 m in diving surveys. On the basis of the collected data sets, the inner shelf (0-60 m) has been subdivided into different portions, following the concept of the Environmental Unit (E.U). Every E.U. presents constant morphological and sedimentological features that, probably, can be associated to specified biological communities. In order to find the relationships between physical settings and communities, geological thematic maps are eventually overlaid and fitted to macrobenthic and fishery spatial distribution maps. The result, based on the rule of the Environmental Impact Assessment, puts into evidence the

  11. Study of (U,Pu)O2 spent fuel matrix alteration under geological disposal conditions: Experimental approach and geochemical modeling

    International Nuclear Information System (INIS)

    Odorowski, Melina

    2015-01-01

    To assess the performance of direct disposal of spent fuel in a nuclear waste repository, researches are performed on the long-term behavior of spent fuel (UO x and MO x ) under environmental conditions close to those of the French disposal site. The objective of this study is to determine whether the geochemistry of the Callovian-Oxfordian (CO x ) clay geological formation and the steel overpack corrosion (producing iron and hydrogen) have an impact on the oxidative dissolution of the (U,Pu)O 2 matrix under alpha radiolysis of water. Leaching experiments have been performed with UO 2 pellets doped with alpha emitters (Pu) and MIMAS MO x fuel (un-irradiated or spent fuel) to study the effect of the CO x groundwater and of the presence of metallic iron upon the oxidative dissolution of these materials induced by the radiolysis of water. Results indicate an inhibiting effect of the CO x water on the oxidative dissolution. In the presence of iron, two different behaviors are observed. Under alpha irradiation as the one expected in the geological disposal, the alteration of UO 2 matrix and MO x fuel is very strongly inhibited because of the consumption of radiolytic oxidative species by iron in solution leading to the precipitation of Fe(III)-hydroxides on the pellets surface. On the contrary, under a strong beta/gamma irradiation field, alteration tracers indicate that the oxidative dissolution goes on and that uranium concentration in solution is controlled by the solubility of UO 2 (am,hyd). This is explained by the shifting of the redox front from the fuel surface to the bulk solution not protecting the fuel anymore. The developed geochemical (CHESS) and reactive transport (HYTEC) models correctly represent the main results and occurring mechanisms. (author) [fr

  12. Food intake during the previous 24 h as a percentage of usual intake: a marker of hypoxia in infants with bronchiolitis: an observational, prospective, multicenter study

    Directory of Open Access Journals (Sweden)

    Corrard François

    2013-01-01

    Full Text Available Abstract Background Hypoxia associated with bronchiolitis is not always easy to assess on clinical grounds alone. The aim of this study was to determine the value of food intake during the previous 24 hours (bottle and spoon feeding, as a percentage of usual intake (24h FI, as a marker of hypoxia, and to compare its diagnostic value with that of usual clinical signs. Methods In this observational, prospective, multicenter study, 18 community pediatricians, enrolled 171 infants, aged from 0 to 6 months, with bronchiolitis (rhinorrhea + dyspnea + cough + expiratory sounds. Infants with risk factors (history of prematurity, chronic heart or lung disorders, breast-fed infants, and infants having previously been treated for bronchial disorders were excluded. The 24h FI, subcostal, intercostal, supracostal retractions, nasal flaring, respiratory rate, pauses, cyanosis, rectal temperature and respiratory syncytial virus test results were noted. The highest stable value of transcutaneous oxygen saturation (SpO2 was recorded. Hypoxia was noted if SpO2 was below 95% and verified. Results 24h FI ≥ 50% was associated with a 96% likelihood of SpO2 ≥ 95% [95% CI, 91–99]. In univariate analysis, 24h FI  Conclusion In practice, the measure of 24 h FI may be useful in identifying hypoxia and deserves further study.

  13. Accuracy of preoperative real-time dynamic transvaginal ultrasound sliding sign in prediction of pelvic adhesions in women with previous abdominopelvic surgery: prospective, multicenter, double-blind study.

    Science.gov (United States)

    Ayachi, A; Bouchahda, R; Derouich, S; Mkaouer, L; Kehila, M; Abouda, H; Channoufi, B; Bouyahia, M; Braham, M; Zhioua, F; Bouchahda, H; Mourali, M

    2018-02-01

    To investigate the role of the transvaginal sonographic (TVS) sliding sign in predicting pelvic adhesions in women with previous abdominopelvic surgery. This was a multicenter, prospective, interventional, double-blind study of patients with a history of abdominopelvic surgery who were undergoing laparoscopy or laparotomy during the 6-month period from March to August 2016 in one of three academic obstetrics and gynecology departments. Prior to surgery, patients were examined by TVS to assess the vesicouterine pouch, uterus, ovaries and pouch of Douglas, using the TVS pelvic sliding sign. Ultrasound findings and medical and surgical data were recorded. We assessed the accuracy of the preoperative TVS sliding sign in the prediction of pelvic adhesions overall and in each compartment separately. During the study period, complete TVS sliding sign and laparoscopic or laparotomic data were available for 107 women. Their mean age was 44.0 (95% CI, 41.6-46.4; range, 20-79) years. Their mean parity was 2.0 (95% CI, 1.7-2.3; range, 0-9) and the mean number of previous abdominal surgical procedures per patient was 1.3 (95% CI, 1.2-1.5; range, 1-4). Adhesions were noted in 27/107 (25.2%) patients. The TVS sliding sign had a sensitivity of 96.3% and specificity of 92.6% in predicting pelvic adhesions. There was a significant relationship between adhesions in each compartment and the TVS sliding sign (P sign is an effective means to detect preoperatively pelvic adhesions in patients with previous abdominopelvic surgery. Use of such a non-invasive and well-tolerated technique could help in the planning of laparoscopy or laparotomy and counseling of these patients. Copyright © 2017 ISUOG. Published by John Wiley & Sons Ltd. Copyright © 2017 ISUOG. Published by John Wiley & Sons Ltd.

  14. Electromagnetic characterization of fractured rock for geological disposal studies of spent nuclear fuel

    Energy Technology Data Exchange (ETDEWEB)

    Eloranta, E. [Radiation and Nuclear Safety Authority, Helsinki (Finland); Ermutlu, M. [Nokia Research Center, Helsinki (Finland); Flykt, M.; Lindell, I.; Nikoskinen, K.; Sihvola, A. [Helsinki Univ. of Technology, Espoo (Finland). Electromagnetics Lab.

    1998-04-01

    In the report, the results of a joint research project carried out in 1991-1997 by the Finnish Radiation and Nuclear Safety Authority (STUK) and the Electromagnetics Laboratory of the Helsinki University of Technology are presented. The main purpose was to create computational models for electric potential responses when the medium is anisotropic and is bounded by a perfect magnetic conductor, a perfect electric conductor, and an anisotropic impedance surface. Furthermore, the geometry of two anisotropic half spaces and a layered medium were considered. The solutions of the problems were made using image theory. For modeling the electric potential in anisotropic medium with inhomogeneities, an integral equation was formulated. Also a wedge structure was treated as an extension to the traditional two parallel plate model of fracture geometry. The equivalentization of fracturing with anisotropy is a research area that still continues that still continues 46 refs. The publication contains also fourteen previous publications by authors

  15. Deconstructing geologic slip rates

    Science.gov (United States)

    Gold, R. D.

    2017-12-01

    Discrepancies between geologic and geodetic slip rates are recognized globally. However, understanding the significance of those discrepancies requires a complete inventory of the sources of uncertainty often deeply hidden or ignored in slip-rate estimates. In this presentation, I will examine underappreciated complexities associated with geologic estimates of fault slip rates along strike-slip faults. Slip-rate measurements are made from geomorphic features displaced by faulting and age constraints derived from chronologic or stratigraphic data. Sources of uncertainty associated with offset measurements include measurement errors, ambiguities in feature reconstructions, and distributed faulting and bulk off-fault deformation. Sources of uncertainty associated with age constraints include analytical uncertainties, inheritance in the sample material, post-depositional contamination, and often most critically, ambiguity in how to associate sample ages with the landforms or deposits from which they were collected. Additional sources of uncertainty associated with slip-rate measurements include the time interval over which geologic slip rates are determined (e.g., number of earthquake cycles) and the impact of secular variation in slip. I will use case studies from the San Andreas fault system, the Walker Lane, and Tibet to explore sources of uncertainty in geologic slip rates and highlight practices that can mitigate those uncertainties. I will emphasize the need for bracketing the age of faulted landforms using numerous geochronometers, documenting numerous offset landforms, and sampling a range of magnitudes of slip in a probabilistic framework.

  16. A preliminary assessment of geologic framework and sediment thickness studies relevant to prospective US submission on extended continental shelf

    Science.gov (United States)

    Hutchinson, Deborah R.; Childs, Jonathan R.; Hammar-Klose, Erika; Dadisman, Shawn; Edgar, N. Terrence; Barth, Ginger A.

    2004-01-01

    Under the provisions of Articles 76 and 77 of the United Nations Convention on the Law of the Sea (UNCLOS), coastal States have sovereign rights over the continental shelf territory beyond 200-nautical mile (nm) from the baseline from which the territorial sea is measured if certain conditions are met regarding the geologic and physiographic character of the legal continental shelf as defined in those articles. These claims to an extended continental shelf must be supported by relevant bathymetric, geophysical and geological data according to guidelines established by the Commission on the Limits of the Continental Shelf (CLCS, 1999). In anticipation of the United States becoming party to UNCLOS, Congress in 2001 directed the Joint Hydrographic Center/Center for Coastal and Ocean Mapping at the University of New Hampshire to conduct a study to evaluate data relevant to establishing the outer limit of the juridical continental shelf beyond 200 nm and to recommend what additional data might be needed to substantiate such an outer limit (Mayer and others, 2002). The resulting report produced an impressive and sophisticated GIS database of data sources. Because of the short time allowed to complete the report, all seismic reflection data were classified together; the authors therefore recommended that USGS perform additional analysis on seismic and related data holdings. The results of this additional analysis are the substance of this report, including the status of geologic framework, sediment isopach research, and resource potential in the eight regions1 identified by Mayer and others (2002) where analysis of seismic data might be crucial for establishing an outer limit . Seismic reflection and refraction data are essential in determining sediment thickness, one of the criteria used in establishing the outer limits of the juridical continental shelf. Accordingly, the initial task has been to inventory public-domain seismic data sources, primarily those regionally

  17. The contribution of previous lameness events and body condition score to the occurrence of lameness in dairy herds: A study of 2 herds.

    Science.gov (United States)

    Randall, L V; Green, M J; Green, L E; Chagunda, M G G; Mason, C; Archer, S C; Huxley, J N

    2018-02-01

    It has been demonstrated that low body condition and previous occurrence of lameness increase the risk of future lameness in dairy cows. To date the population attributable fraction (PAF), which provides an estimate of the contribution that a risk factor makes toward the total number of disease events in a population, has not been explored for lameness using longitudinal data with repeated measures. Estimation of PAF helps to identify control measures that could lead to the largest improvements on-farm. The aim of this study was to use longitudinal data to evaluate the proportion of lameness that could be avoided in 2 separate herds (2 populations) through (1) reduced recurrence of previous lameness events, (2) and moving body condition score (BCS) into more optimal ranges. Data were obtained from 2 UK dairy herds: herd A, a 200-cow herd with 8 yr of data from a total of 724 cows where lameness events were based on weekly locomotion scores (LS; 1 to 5 scale), and herd B, a 600-cow herd with data recorded over 44 mo from a total of 1,040 cows where treatment of clinical cases was used to identify lameness events. The PAF for categories of BCS were estimated using a closed equation appropriate for multiple exposure categories. Simulation models were used to explore theoretical scenarios to reflect changes in BCS and recurrence of previous lameness events in each herd. For herd A, 21.5% of the total risk periods (cow-weeks) contained a lameness event (LS 3, 4, or 5), 96% of which were repeat events and 19% were recorded with BCS events were based on 2 consecutive weeks of LS 4 or 5, 4% of risk periods were recorded as lame, of which 89.5% were repeat events. For herd B, 16.3% of the total risk periods (consecutive 30 d) contained a lameness event (72.6% were repeat events) and 20% were recorded with BCS ≤2 (0 to 120 d previously). The median PAF for all previous lameness was between 79 and 83% in the 2 herds. Between 9 and 21% of lameness events could be attributed

  18. A pilot study of a metronomic chemotherapy regimen with weekly low-dose docetaxel for previously treated non-small cell lung cancer

    Directory of Open Access Journals (Sweden)

    Yokoi T

    2012-05-01

    Full Text Available Takashi Yokoi, Takeshi Tamaki, Toshiki Shimizu, Shosaku NomuraFirst Department of Internal Medicine, Kansai Medical University, Moriguchi City, Osaka, JapanBackground: Low-dose metronomic (LDM chemotherapy is a novel approach that involves frequent administration of a low dose of chemotherapeutic agent without a long interval.Purpose: The aim of this clinical pilot study was to evaluate the toxicity and efficacy of LDM chemotherapy with weekly low-dose docetaxel for previously treated non-small cell lung cancer (NSCLC.Patients and methods: The enrolled patients received 15 mg/m2 of docetaxel intravenously on a weekly basis without any interval.Results: Twenty-seven patients were enrolled in the study; 20 were men, and seven were women. The median age was 62 years (range: 32–75. Eleven patients were stage IIIB, and 16 were stage IV. The Eastern Cooperative Oncology Group performance status was 0 or 1. There was no severe hematological adverse effect; importantly, there was no neutropenia or thrombocytopenia. The objective response rate was 7.4% and the disease control rate was 51.9%. The median survival time was 16.4 months (95% CI: 5.7–36.4.Conclusion: Our preliminary results indicate that our metronomic regimen was well tolerated and active in patients with previously treated NSCLC. Thus, further investigation of this LDM regimen is warranted.Keywords: optimal biological dose, metronomic chemotherapy, docetaxel

  19. Outcome of secondary high-grade glioma in children previously treated for a malignant condition: A study of the Canadian Pediatric Brain Tumour Consortium

    International Nuclear Information System (INIS)

    Carret, Anne-Sophie; Tabori, Uri; Crooks, Bruce; Hukin, Juliette; Odame, Isaac; Johnston, Donna L.; Keene, Daniel L.; Freeman, Carolyn; Bouffet, Eric

    2006-01-01

    Background and purpose: Reports of secondary high-grade glioma (HGG) in survivors of childhood cancer are scarce. The aim of this study was to review the pattern of diagnosis, the treatment, and outcome of secondary pediatric HGG. Patients and methods: We performed a multi-center retrospective study among the 17 paediatric institutions participating in the Canadian Pediatric Brain Tumour Consortium (CPBTC). Results: We report on 18 patients (14 males, 4 females) treated in childhood for a primary cancer, who subsequently developed a HGG as a second malignancy. All patients had previously received radiation therapy +/- chemotherapy for either acute lymphoblastic leukaemia (n = 9) or solid tumour (n = 9). All HGG occurred within the previous radiation fields. At the last follow-up, 17 patients have died and the median survival time is 9.75 months. Conclusion: Although aggressive treatment seems to provide sustained remissions in some patients, the optimal management is still to be defined. Further documentation of such cases is necessary in order to better understand the pathogenesis, the natural history and the prevention of these tumours

  20. Indoor Radon in Micro-geological Setting of an Indigenous Community in Canada: A Pilot Study for Hazard Identification.

    Science.gov (United States)

    Sarkar, Atanu; Wilton, Derek Hc; Fitzgerald, Erica

    2017-04-01

    Radon is the second leading cause of lung cancer after smoking. In Canada, the health authorities have no access to comprehensive profile of the communities built over uranium-rich micro-geological settings. The present indoor radon monitoring guideline is unable to provide an accurate identification of health hazards due to discounting several parameters of housing characteristics. To explore indoor radon levels in a micro-geological setting known for high uranium in bedrock and to develop a theoretical model for a revised radon testing protocol. We surveyed a remote Inuit community in Labrador, located in the midst of uranium belt. We selected 25 houses by convenience sampling and placed electret-ion-chamber radon monitoring devices in the lowest levels of the house (basement/crawl space). The standard radon study questionnaire developed and used by Health Canada was used. 7 (28%) houses had radon levels above the guideline value (range 249 to 574 Bq/m 3 ). Housing characteristics, such as floors, sump holes, ventilation, and heating systems were suspected for high indoor radon levels and health consequences. There is a possibility of the existence of high-risk community in a low-risk region. The regional and provincial health authorities would be benefited by consulting geologists to identify potentially high-risk communities across the country. Placing testing devices in the lowest levels provides more accurate assessment of indoor radon level. The proposed protocol, based on synchronized testing of radon (at the lowest level of houses and in rooms of normal occupancy) and thorough inspection of the houses will be a more effective lung cancer prevention strategy.

  1. Does using testicular sperm retrieval rather than ejaculated spermatozoa improve reproductive outcomes in couples with previous ART failure and poor ovarian response? A case-controlled study.

    Science.gov (United States)

    Gilman, A R; Younes, G; Tannus, S; Son, W Y; Chan, P; Buckett, W

    2018-01-01

    The objective of this study was to assess whether testicular-retrieved spermatozoa improve reproductive outcomes compared to fresh ejaculate in women with poor ovarian response and a history of previous ART failure. The study was performed as a retrospective case-control study at a university-based reproductive center in Montreal, Quebec, Canada. Eighteen poor-responder patients were matched 3 : 1 with 54 controls. Poor responders were defined as those with ≤3 oocytes retrieved at oocyte pickup. Cases were identified as poor responders, and only those with previous IVF failure(s) as an indication for testicular-retrieved spermatozoa were included. Controls were age and cycle attempt number matched. All patients were included only once. From January 1, 2009 to December 31, 2015, all patients and controls underwent an IVF cycle using ICSI with either testicular spermatozoa or ejaculated spermatozoa, respectively. Outcomes included live birth rate, pregnancy rate, miscarriage rate, oocyte number, and embryo transfer (ET) day. The results showed live birth rates, pregnancy rates, and miscarriage rates were similar. There were fewer day 2 ETs (8.5% vs. 48.6%, p = 0.01) and more day 5 blastocyst transfers (25.0% vs. 5.4%, p = 0.05) in the testicular sperm retrieval group compared to controls and thus an overall suggestion of better embryo quality in the testicular sperm group. Overall, however, the use of testicular sperm retrieval appears to add little. Women with poor ovarian response typically have a poor prognosis with respect to live birth rates, and this is further supported in this study. The suggestion of better embryo quality in the testicular-retrieved sperm group would need to be further assessed in a larger multicentered study. © 2017 American Society of Andrology and European Academy of Andrology.

  2. Geological exploration for a high-temperature aquifer thermal energy storage (HT-ATES) system: a case study from Oman

    Science.gov (United States)

    Winterleitner, Gerd; Schütz, Felina; Huenges, Ernst

    2017-04-01

    A collaborative research programme between the German Research Centre for Geoscience, Potsdam (GFZ) and The Research Council of Oman (TRC) is underway, which aims to develop and implement an innovative concept of a sustainable thermally driven cooling system in combination with a HT-ATES in northern Oman. The system will use an absorption chiller for cold supply, which nominally requires water of around 100°C as energy source. Solar collectors will provide this thermal energy and energy surpluses during daytimes will be stored to ensure a continuous operation of the cooling system. An integral part of this project is, therefore, the development of an efficient HT-ATES (100°C), which is based on temporary storage and recovery of thermal energy through hot water injection in subsurface aquifer horizons. Thus, an accurate thermal and fluid flow characterisation of potential reservoir horizons is essential to ensure optimal efficiency of the cooling system. The study area is located in the Al Khwad area, approximately 40 km to the west of Muscat. The area is characterised by a thick Cenozoic mixed carbonate-siliciclastic sedimentary succession, containing at least 3 aquifer horizons. We use a multidisciplinary approach for the initial ATES exploration and development phase, including traditional geological fieldwork dovetailed with virtual outcrop geology, thin-section analyses, geological modelling and reservoir fluid flow forecasting analyses. Our first results indicate two potential storage horizons: (1) a Miocene-aged clastic-dominated alluvial fan system and (2) an Eocene carbonate-dominated sequence. The alluvial fan system is characterised by a more than 300 m thick, coarse-clastic succession of coalesced individual fans. Thermal and hydraulic parameters are favourable for gravel and sandstone intervals but reservoir architecture is complex due to multiple generations of interconnecting fans with highly heterogeneous facies distributions. The Eocene carbonates

  3. Design studies on the engineered barrier system and on the in-situ experiments under the conditions of geological environment in Horonobe

    International Nuclear Information System (INIS)

    Kurihara, Yuji; Yui, Mikazu; Tanai, Kenji

    2004-04-01

    Following studies have been done in this papers in order to apply the technologies based on H12 report to the actual geological conditions of Horonobe underground research laboratory. 1) Reconsidering the process of repository design, the design process charts of a repository were presented. In the H12 report, the design process of the engineering barrier system was followed by the facility design process. In this paper, the both processes were placed in parallel position. 2) The relation between geological conditions and the performance of engineering barrier systems and the specifications of engineering barrier systems was arranged and the geological information needed for design of engineering barrier were selected. 3) The appropriate form of geological information as input-data for design were showed and the procedure for setting input-data was presented. 4) Based on the state of geological investigations at Horonobe, mechanical input-data were arranged for the design of the in-situ experiments on engineered barrier system at HORONOBE. 5) The stability of the hall for the in-situ experiments was studied by numerical analysis and the results indicated that there are difference in stability between the depth of 500 m and 570 m. (author)

  4. Preliminary Study of Long-term Geological Stability for HLW Disposal in Korea

    International Nuclear Information System (INIS)

    Hwang, Jae Ha; Kim, Ju Yong; Cho, Deung Lyong

    2004-02-01

    It was summarized previous works of the Al-in-hornblende geobarometer to quantify emplacement depths of the Cretaceous Bulgugsa granites and the Triassic-Jurassic Daebo granites in Korea. When calculated using the equation of Schmidt, the emplacement pressures of the Bulgugsa granites are less than 2.8 kb and those of the Daebo granites range from 3.4 to 7.8 kb. Assuming that the crustal thickness varies simply due to erosion and uplift, the crustal thickness of South Korea during the Jurassic can be calculated by adding average emplacement depth of the Jurassic granites to average thickness of present-day crust, which corresponds to about 50 km. The lower I terrace among the marine terraces had been formed in the Last Interglacial culmination stage(MIS 5e) by the amino-acid date, the identification of Ata tephra, the pollen assemblage and the relationships with the thalassostatic terrace of the Last Interglacial culmination stage, respectively. Ancient shoreline height of the lower marine terrace I is 18m on the whole southeastern coast of Korea. Therefore, if we assume that the sea level of the last Interglacial culmination period(125ka BP) was 6m higher than that of the present, the amount of net uplift since the last Interglacial culmination is about 12m, and if we suppose a constant-rate uplift, then the uplift rate in the southeastern coast area will be about 0.1m/ka

  5. Vitamin D deficiency in medical patients at a central hospital in Malawi: a comparison with TB patients from a previous study.

    Directory of Open Access Journals (Sweden)

    Yamikani Mastala

    Full Text Available OBJECTIVES: To determine the prevalence of vitamin D deficiency (VDD in adult medical, non-tuberculous (non-TB patients. To investigate associations with VDD. To compare the results with a similar study in TB patients at the same hospital. DESIGN: Cross-sectional sample. SETTING: Central hospital in Malawi. PARTICIPANTS: Adult non-TB patients (n = 157, inpatients and outpatients. OUTCOME MEASURES: The primary outcome was the prevalence of VDD. Potentially causal associations sought included nutritional status, in/outpatient status, HIV status, anti-retroviral therapy (ART and, by comparison with a previous study, a diagnosis of tuberculosis (TB. RESULTS: Hypovitaminosis D (≤75 nmol/L occurred in 47.8% (75/157 of patients, 16.6% (26/157 of whom had VDD (≤50 nmol/L. None had severe VDD (≤25 nmol/L. VDD was found in 22.8% (23/101 of in-patients and 5.4% (3/56 of out-patients. In univariable analysis in-patient status, ART use and low dietary vitamin D were significant predictors of VDD. VDD was less prevalent than in previously studied TB patients in the same hospital (68/161 = 42%. In multivariate analysis of the combined data set from both studies, having TB (OR 3.61, 95%CI 2.02-6.43 and being an in-patient (OR 2.70, 95%CI 1.46-5.01 were significant independent predictors of VDD. CONCLUSIONS: About half of adult medical patients without TB have suboptimal vitamin D status, which is more common in in-patients. VDD is much more common in TB patients than non-TB patients, even when other variables are controlled for, suggesting that vitamin D deficiency is associated with TB.

  6. Reduced live-birth rates after IVF/ICSI in women with previous unilateral oophorectomy: results of a multicentre cohort study.

    Science.gov (United States)

    Lind, Tekla; Holte, Jan; Olofsson, Jan I; Hadziosmanovic, Nermin; Gudmundsson, Johannes; Nedstrand, Elizabeth; Lood, Mikael; Berglund, Lars; Rodriguez-Wallberg, Kenny

    2018-02-01

    Is there a reduced live-birth rate (LBR) after IVF/ICSI treatment in women with a previous unilateral oophorectomy (UO)? A significantly reduced LBR after IVF/ICSI was found in women with previous UO when compared with women with intact ovaries in this large multicentre cohort, both crudely and after adjustment for age, BMI, fertility centre and calendar period and regardless of whether the analysis was based on transfer of embryos in the fresh cycle only or on cumulative results including transfers using frozen-thawed embryos. Similar pregnancy rates after IVF/ICSI have been previously reported in case-control studies and small cohort studies of women with previous UO versus women without ovarian surgery. In all previous studies multiple embryos were transferred. No study has previously evaluated LBR in a large cohort of women with a history of UO. This research was a multicentre cohort study, including five reproductive medicine centres in Sweden: Carl von Linné Clinic (A), Karolinska University Hospital (B), Uppsala University Hospital (C), Linköping University Hospital (D) and Örebro University Hospital (E). The women underwent IVF/ICSI between January 1999 and November 2015. Single embryo transfer (SET) was performed in approximately 70% of all treatments, without any significant difference between UO exposed women versus controls (68% versus 71%), respectively (P = 0.32), and a maximum of two embryos were transferred in the remaining cases. The dataset included all consecutive treatments and fresh and frozen-thawed cycles. The exposed cohort included 154 women with UO who underwent 301 IVF/ICSI cycles and the unexposed control cohort consisted of 22 693 women who underwent 41 545 IVF/ICSI cycles. Overall, at the five centres (A-E), the exposed cohort underwent 151, 34, 35, 41 and 40 treatments, respectively, and they were compared with controls of the same centre (18 484, 8371, 5575, 4670 and 4445, respectively). The primary outcome was LBR, which was

  7. Everolimus Plus Exemestane in Advanced Breast Cancer: Safety Results of the BALLET Study on Patients Previously Treated Without and with Chemotherapy in the Metastatic Setting.

    Science.gov (United States)

    Generali, Daniele; Montemurro, Filippo; Bordonaro, Roberto; Mafodda, Antonino; Romito, Sante; Michelotti, Andrea; Piovano, Pierluigi; Ionta, Maria Teresa; Bighin, Claudia; Sartori, Donata; Frassoldati, Antonio; Cazzaniga, Marina Elena; Riccardi, Ferdinando; Testore, Franco; Vici, Patrizia; Barone, Carlo Antonio; Schirone, Alessio; Piacentini, Federico; Nolè, Franco; Molino, Annamaria; Latini, Luciano; Simoncini, Edda Lucia; Roila, Fausto; Cognetti, Francesco; Nuzzo, Francesco; Foglietta, Jennifer; Minisini, Alessandro Marco; Goffredo, Francesca; Portera, Giuseppe; Ascione, Gilda; Mariani, Gabriella

    2017-06-01

    The BALLET study was an open-label, multicenter, expanded access study designed to allow treatment with everolimus plus exemestane in postmenopausal women with hormone receptor-positive metastatic breast cancer progressed following prior endocrine therapy. A post hoc analysis to evaluate if previous chemotherapy in the metastatic setting affects the safety profile of the combination regimen of everolimus and exemestane was conducted on the Italian subset, as it represented the major part of the patients enrolled (54%). One thousand one hundred and fifty-one Italian patients were included in the present post hoc analysis, which focused on two sets of patients: patients who never received chemotherapy in the metastatic setting (36.1%) and patients who received at least one chemotherapy treatment in the metastatic setting (63.9%). One thousand one hundred and sixteen patients (97.0%) prematurely discontinued the study drug, and the main reasons reported were disease progression (39.1%), local reimbursement of everolimus (31.1%), and adverse events (AEs) (16.1%). The median duration of study treatment exposure was 139.5 days for exemestane and 135.0 days for everolimus. At least one AE was experienced by 92.5% of patients. The incidence of everolimus-related AEs was higher (83.9%) when compared with those that occurred with exemestane (29.1%), and the most commonly reported everolimus-related AE was stomatitis (51.3%). However, no significant difference in terms of safety related to the combination occurred between patients without and with chemotherapy in the metastatic setting. Real-life data of the Italian patients BALLET-related cohort were an adequate setting to state that previous chemotherapy did not affect the safety profile of the combination regimen of everolimus and exemestane. With the advent of new targeted agents for advanced or metastatic breast cancer, multiple lines of therapy may be possible, and components of the combined regimens can overlap from

  8. Higher frequency of hamstring injuries in elite track and field athletes who had a previous injury to the ankle - a 17 years observational cohort study.

    Science.gov (United States)

    Malliaropoulos, Nikolaos; Bikos, Georgios; Meke, Maria; Vasileios, Korakakis; Valle, Xavier; Lohrer, Heinz; Maffulli, Nicola; Padhiar, Nat

    2018-01-01

    Inversion injury to the ankle and hamstring injuries are common problems in most sports. It is not known whether these injuries constitute a predisposing factor or a precursor of injury or re-injury of these anatomical locations. Therefore, we wished to test the hypothesis that a previous inversion ankle injury exerted a significant effect on the chance of an athlete suffering from a subsequent ipsilateral hamstring injury and vice versa. In an observational cohort study over 17 years (1998-2015), 367 elite track and field athletes, were grouped according to their first traumatic isolated ankle or hamstring injury. Fifty athletes experienced both injuries. The Mann-Whitney U and Chi-square tests ( p  < 0.05) were performed to test possible associations of ankle and hamstring injury with age, gender, athletics discipline, grade, and type of antecedent injury. Athletes with a preceding ankle injury had a statistically significantly higher chance of experiencing a subsequent hamstring injury compared with athletes who had experienced a hamstring injury as their first traumatic event (x 2  = 4.245, p  = 0.039). The proportion of both ankle and hamstring injury events was not statistically different between female (18%) and male (11%) athletes. Age and grade of injury did not influence the proportion of ankle and/or hamstring injury events. There is a statistically significantly higher frequency of hamstring injuries in elite track and field athletes having experienced a previous ankle ligament injury.

  9. A longitudinal study of relationships between previous academic achievement, emotional intelligence and personality traits with psychological health of medical students during stressful periods.

    Science.gov (United States)

    Yusoff, Muhamad Saiful Bahri; Esa, Ab Rahman; Mat Pa, Mohamad Najib; Mey, See Ching; Aziz, Rosniza Abdul; Abdul Rahim, Ahmad Fuad

    2013-01-01

    There is considerable evidence that emotional intelligence, previous academic achievement (i.e. cumulative grade point average (GPA)) and personality are associated with success in various occupational settings. This study evaluated the relationships of these variables with psychological health of first year medical students during stressful periods. A 1-year prospective study was done with students accepted into the School of Medical Sciences, Universiti Sains Malaysia. Information on emotional intelligence, GPA and personality traits were obtained prior to admission. The validated Universiti Sains Malaysia Emotional Quotient Inventory and Universiti Sains Malaysia Personality Inventory were used to measure emotional intelligence and personality traits, respectively. Stress, anxiety and depression were measured by the 21-item Depression Anxiety Stress Scale during the end-of-course (time 1) and final (time 2) examinations. At the less stressful period (time 1), stress level was associated with agreeableness and the final GPA, anxiety level was associated with emotional control and emotional conscientiousness and depression level was associated with the final GPA and extraversion. At the more stressful period (time 2), neuroticism associated with stress level, anxiety level was associated with neuroticism and emotional expression, and depression level was associated with neuroticism. This study found that neuroticism was the strongest associated factor of psychological health of medical students during their most stressful testing period. Various personality traits, emotional intelligence and previous academic performance were associated factors of psychological health during a less stressful period. These data suggest that early identification of medical students who are vulnerable to the stressful environment of medical schools might help them maintain psychological well-being during medical training.

  10. A COMPARATIVE STUDY OF PERINATAL OUTCOME IN WOMEN WITH RECURRENT PREECLAMPSIA TO WOMEN WITH PRE-ECLAMPSIA WHO WERE NORMOTENSIVE DURING THEIR PREVIOUS PREGNANCIES

    Directory of Open Access Journals (Sweden)

    Beena Guhan

    2016-08-01

    Full Text Available BACKGROUND AND OBJECTIVE Pre-eclampsia is a systemic syndrome that occurs in 3-5% of the pregnant women and is the leading cause of maternal/neonatal morbidity and mortality. We designed a study to compare perinatal outcome in women with recurrent preeclampsia to women with women with pre-eclampsia who were normotensive during their previous pregnancies. MATERIALS AND METHODS This study was conducted in Dept. of Obstetrics and Gynaecology, Institute of Maternal and Child Health, Government Medical College, Kozhikode for a period of 1 year from March 2013 to February 2014. We conducted this study in multiparous women who developed pre-eclampsia in index pregnancy (n=110. Among these, women who had pre-eclampsia in previous pregnancies (n=55 were compared to those who remained normotensive during their prior pregnancies (n=55. Maternal and foetal variables were compared. Multivariate logistic analyses were performed to examine the impact of pre-eclampsia on foetal outcome, preterm delivery, IUGR, still births adjusted for confounding variables. RESULTS No statistical significant difference was observed between the 2 groups in terms of age, gravida, parity. Women who experienced recurrent pre-eclampsia were at elevated risk for early onset of pre-eclampsia, deranged laboratory investigations (Hepatic and Renal parameters, Coagulation Profile, higher chances of maternal complications, foetal mortality and morbidity (Statistically significant P <0.05. Foetal loss was higher in women with recurrent pre-eclampsia (14.5% than in women with pre-eclampsia who had normotensive pregnancy history (1.8%. CONCLUSION Women with recurrent pre-eclampsia had a higher rate of perinatal loss compared to women with pre-eclampsia who were normotensive in their prior pregnancies.

  11. A geologic and geophysic study of the Sierra de Pena Blanca, in the state of Chihuahua, Mexico

    International Nuclear Information System (INIS)

    Lopez S, F.A.

    1976-01-01

    Within the sistematic aerial exploration program realized by the Instituto Nacional de Energia Nuclear, an aeroradiometric study was carried out in the zone which includes Sierra de Pena Blanca. This study took into consideration the former and present geological investigations and compromised the sierra together with the bordering valleys. The main objective consists in the localization of areas presenting favorable conditions for the existence of uranium isotopes minerlization, in order to determine a mineralized body or ore deposit. For that purpose the area was explored with an airplane to which a differential gamma rays spectrometer was adapted, this spectrometer will show us clearly the integration of the number of radiations which fall into the detectors obtaining this way a valuable information about the radiometric anomalous sites of the studied zone and also about the existence of bismuth, thallium and the abundant potassium of the igneous rocks. These anomalies are under the stage of ground verification, this stage includes a superficial study and the study of the underlying rocks through drilling, radiometric logs and chemical analysis of the samples. In fact, through this method we can obtain very truthful data. (author)

  12. Evaluation of geological conditions for coalbed methane occurrence based on 3D seismic information: a case study in Fowa region, Xinjing coal mine, China

    Science.gov (United States)

    Li, Juanjuan; Li, Fanjia; Hu, Mingshun; Zhang, Wei; Pan, Dongming

    2017-04-01

    The research on geological conditions of coalbed methane (CBM) occurrence is of great significance for predicting the high abundance CBM rich region and gas outburst risk area pre-warning. The No. 3 coal seam, in Yangquan coalfield of Qinshui basin, is the research target studied by 3D seismic exploration technique. The geological factors which affect CBM occurrence are interpreted based on the 3D seismic information. First, the geological structure (faults, folds, and collapse columns) is found out by the 3D seismic structural interpretation and the information of buried depth and thickness of the coal seam is calculated by the seismic horizons. Second, 3D elastic impedance (EI) and natural gamma attribute volumes are generated by prestack EI inversion and multi-attribute probabilistic neural network (PNN) inversion techniques which reflect the information of coal structure types and lithology of the roof and floor. Then, the information of metamorphic degree of seam and hydrogeology conditions can be obtained by the geological data. Consequently, geological conditions of CBM occurrence in No. 3 coal seam are evaluated which will provide scientific reference for high abundance CBM rich region prediction and gas outburst risk area pre-warning.

  13. Prevalence of high-risk human papillomavirus and cervical intraepithelial neoplasias in a previously unscreened population--a pooled analysis from three studies.

    Science.gov (United States)

    Basu, Partha; Mittal, Srabani; Bhaumik, Suchismita; Mandal, Shyam Sunder; Samaddar, Anusree; Ray, Chinmayi; Siddiqi, Maqsood; Biswas, Jaydip; Sankaranarayanan, Rengaswamy

    2013-04-01

    Population prevalence of human papillomavirus (HPV) and cervical intraepithelial neoplasias (CIN) is an important indicator to judge the disease burden in the community, to monitor the performance of cervical cancer screening program and to assess the impact of HPV vaccination program. India being a country without any cervical cancer screening program has no published data on the population prevalence of CIN and only a few large community-based studies to report the high-risk HPV prevalence. The objective of our study was to study HPV and CIN prevalence in a previously unscreened population. We pooled together the results of three research studies originally designed to assess the performance of visual inspection after acetic acid application and Hybrid Capture 2 (HC 2). Nearly 60% of the screened women had colposcopy irrespective of their screening test results. The diagnosis and grading of cervical neoplasias were based on histology. The age standardized prevalence of HPV by HC 2 test was 6.0%. Age-adjusted prevalence of CIN1 and CIN2 was 2.3% and 0.5%, respectively. The age-adjusted prevalence of CIN3 was 0.4% and that of invasive cancer was 0.2%. The prevalence of high-risk HPV was relatively low in the population we studied, which is reflected in the low prevalence of high-grade CIN. The prevalence of CIN3 remained constant across age groups due to absence of screening. Copyright © 2012 UICC.

  14. Phase II study of a 3-day schedule with topotecan and cisplatin in patients with previously untreated small cell lung cancer and extensive disease

    DEFF Research Database (Denmark)

    Sorensen, M.; Lassen, Ulrik Niels; Jensen, Peter Buhl

    2008-01-01

    and cisplatin are needed. The aim of this phase II study was to establish the response rate and response duration in chemo-naive patients with SCLC receiving a 3-day topotecan and cisplatin schedule. METHODS: Simons optimal two-stage design was used. Patients with previously untreated extensive disease SCLC......INTRODUCTION: Treatment with a topoisomerase I inhibitor in combination with a platinum results in superior or equal survival compared with etoposide-based treatment in extensive disease small cell lung cancer (SCLC). Five-day topotecan is inconvenient and therefore shorter schedules of topotecan......, adequate organ functions and performance status less than 3 were eligible. Topotecan (2.0 mg/m, intravenously) was administered on days 1 to 3 with cisplatin (50 mg/m, intravenously) on day 3 every 3 weeks for a total of six cycles. RESULTS: Forty-three patients received 219 cycles of chemotherapy. Median...

  15. Status of geological studies undertaken in France on the Oklo deposit since the Libreville Symposium

    International Nuclear Information System (INIS)

    Weber, F.

    1978-01-01

    The questions posed since the Libreville symposium can be grouped under four headings: origin of the deposits and the over-concentrations; degree of burial reached by the series; temperatures attained during the reactions, and effects of the reactions; perturbations subsequent to the reactions. These questions have been the subject of multidisciplinary investigations, including conventional petrographic and mineralogical investigations (Cogema, Fontenay-aux-Roses and the Centre for Sedimentology and Geochemistry of the Surface, Strasbourg), a study of fluid inclusions (Centre for Petrographic and Geochemical Research, Nancy), studies of organic material (French Institute of Petroleum, Rueil, and Cerchar, Verneuil-en-Halatte) and a study of fission traces (Rene Barnas Laboratory, Orsay). (author)

  16. 2011 Oregon Department of Geology and Mineral Industries (DOGAMI) Lidar: Cascade Volcano Observatory (CVO) Newberry Study Area

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Oregon Department of Geology & Mineral Industries (DOGAMI) contracted with Watershed Sciences, Inc. to collect high resolution topographic LiDAR data for...

  17. EXPERIMENTAL CHALLENGE STUDY OF FV3-LIKE RANAVIRUS INFECTION IN PREVIOUSLY FV3-LIKE RANAVIRUS INFECTED EASTERN BOX TURTLES (TERRAPENE CAROLINA CAROLINA) TO ASSESS INFECTION AND SURVIVAL.

    Science.gov (United States)

    Hausmann, Jennifer C; Wack, Allison N; Allender, Matthew C; Cranfield, Mike R; Murphy, Kevin J; Barrett, Kevin; Romero, Jennell L; Wellehan, James F X; Blum, Stella A; Zink, M Christine; Bronson, Ellen

    2015-12-01

    The Maryland Zoo in Baltimore experienced an outbreak of Frog virus-3 (FV3)-like ranavirus during the summer of 2011, during which 14 of 27 (52%) of its captive eastern box turtles (Terrapene carolina carolina) survived. To assess survival, immunity, and viral shedding, an experimental challenge study was performed in which the surviving, previously infected turtles were reinfected with the outbreak strain of FV3-like ranavirus. Seven turtles were inoculated with virus intramuscularly and four control turtles received saline intramuscularly. The turtles were monitored for 8 wk with blood and oral swabs collected for quantitative polymerase chain reaction (qPCR). During that time, one of seven (14%) inoculated turtles and none of the controls (0%) died; there was no significant difference in survival. Clinical signs of the inoculated turtles, except for the turtle that died, were mild compared to the original outbreak. Quantitative PCR for FV3-like ranavirus on blood and oral swabs was positive for all inoculated turtles and negative for all controls. The turtle that died had intracytoplasmic inclusion bodies in multiple organs. Three inoculated and two control turtles were euthanized at the end of the study. No inclusion bodies were present in any of the organs. Quantitative PCR detected FV3-like ranavirus in the spleen of a control turtle, which suggested persistence of the virus. The surviving five turtles were qPCR-negative for FV3-like ranavirus from blood and oral swabs after brumation. Quantitative PCR for Terrapene herpesvirus 1 found no association between ranavirus infection and herpesvirus loads. In conclusion, previously infected eastern box turtles can be reinfected with the same strain of FV3-like ranavirus and show mild to no clinical signs but can shed the virus from the oral cavity.

  18. EFFECT OF TOPOGRAPHIC AND GEOLOGIC HETEROGENEITIES ...

    African Journals Online (AJOL)

    Geologic heterogeneities and topographic variations in relation to aquifer distribution ad occurrence in Akwa Ibom State have been assessed based on geologic and geophysical studies sixty-six sounding points together with electric log responses of representative wells together with surface geologic data have been ...

  19. A slingram survey on the Nevada Test Site: part of an integrated geologic geophysical study of site evaluation for nuclear waste disposal

    Science.gov (United States)

    Flanigan, Vincent J.

    1979-01-01

    A slingram geophysical survey was made in early 1978 as part of the integrated geologlcal-geophysical study aimed at evaluating the Eleana Formation as a possible repository for nuclear waste. The slingram data were taken over an alluvial fan and pediments along the eastern flank of Syncline Ridge about 45 km north of Mercury, Nevada, on the Nevada Test Site. The data show that the more conductive argillaceous Eleana Formation varies in depth from 40 to 85 m from west to east along traverse lines. Northeast-trending linear anomalies suggest rather abrupt changes in subsurface geology that may be associated with faults and fractures. The results of the slingram survey will, when interpreted in the light of other geologic and geophysical evidence, assist in understanding the shallow parts of the geologic setting of the Eleana Formation.

  20. Magnetic surveying as an aid to geological mapping: a case study ...

    African Journals Online (AJOL)

    A magnetic map of the Obafemi Awolowo University (OAU) Campus, in Ile-Ife, was produced from ground magnetic measurements on all the roads and footpaths. The study was aimed at improving our knowledge of the structural disposition of the lithologies within the area. The magnetic data obtained were subjected to ...

  1. NChina16: A stable geodetic reference frame for geological hazard studies in North China

    Science.gov (United States)

    Wang, Guoquan; Bao, Yan; Gan, Weijun; Geng, Jianghui; Xiao, Gengru; Shen, Jack S.

    2018-04-01

    We have developed a stable North China Reference Frame 2016 (NChina16) using five years of continuous GPS observations (2011.8-2016.8) from 12 continuously operating reference stations (CORS) fixed to the North China Craton. Applications of NChina16 in landslide and subsidence studies are illustrated in this article. A method for realizing a regional geodetic reference frame is introduced. The primary result of this study is the seven parameters for transforming Cartesian ECEF (Earth-Centered, Earth-Fixed) coordinates X, Y, and Z from the International GNSS Service Reference Frame 2008 (IGS08) to NChina16. The seven parameters include the epoch that is used to align the regional reference frame to IGS08 and the time derivatives of three translations and three rotations. The GIPSY-OASIS (V6.4) software package was used to obtain the precise point positioning (PPP) daily solutions with respect to IGS08. The frame stability of NChina16 is approximately 0.5 mm/year in both horizontal and vertical directions. This study also developed a regional model for correcting seasonal motions superimposed into the vertical component of the GPS-derived displacement time series. Long-term GPS observations (1999-2016) from five CORS in North China were used to develop the seasonal model. According to this study, the PPP daily solutions with respect to NChina16 could achieve 2-3 mm horizontal accuracy and 4-5 mm vertical accuracy after being modified by the regional model. NChina16 will be critical to study geodynamic problems in North China, such as earthquakes, faulting, subsidence, and landslides. The regional reference frame will be periodically updated every few years to mitigate degradation of the frame with time and be synchronized with the update of IGS reference frame.

  2. Women's decision-making processes and the influences on their mode of birth following a previous caesarean section in Taiwan: a qualitative study.

    Science.gov (United States)

    Chen, Shu-Wen; Hutchinson, Alison M; Nagle, Cate; Bucknall, Tracey K

    2018-01-17

    Vaginal birth after caesarean (VBAC) is an alternative option for women who have had a previous caesarean section (CS); however, uptake is limited because of concern about the risks of uterine rupture. The aim of this study was to explore women's decision-making processes and the influences on their mode of birth following a previous CS. A qualitative approach was used. The research comprised three stages. Stage I consisted of naturalistic observation at 33-34 weeks' gestation. Stage II involved interviews with pregnant women at 35-37 weeks' gestation. Stage III consisted of interviews with the same women who were interviewed postnatally, 1 month after birth. The research was conducted in a private medical centre in northern Taiwan. Using a purposive sampling, 21 women and 9 obstetricians were recruited. Data collection involved in-depth interviews, observation and field notes. Constant comparative analysis was employed for data analysis. Ensuring the safety of mother and baby was the focus of women's decisions. Women's decisions-making influences included previous birth experience, concern about the risks of vaginal birth, evaluation of mode of birth, current pregnancy situation, information resources and health insurance. In communicating with obstetricians, some women complied with obstetricians' recommendations for repeat caesarean section (RCS) without being informed of alternatives. Others used four step decision-making processes that included searching for information, listening to obstetricians' professional judgement, evaluating alternatives, and making a decision regarding mode of birth. After birth, women reflected on their decisions in three aspects: reflection on birth choices; reflection on factors influencing decisions; and reflection on outcomes of decisions. The health and wellbeing of mother and baby were the major concerns for women. In response to the decision-making influences, women's interactions with obstetricians regarding birth choices

  3. Introduction to thematic collection “Historical and geological studies of earthquakes”

    Directory of Open Access Journals (Sweden)

    Kenji Satake

    2017-11-01

    Full Text Available Abstract This thematic collection contains eight papers mostly presented at the 2016 AOGS meeting in Beijing. Four papers describe historical earthquake studies in Europe, Japan, and China; one paper uses modern instrumental data to examine the effect of giant earthquakes on the seismicity rate; and three papers describe paleoseismological studies using tsunami deposit in Japan, marine terraces in Philippines, and active faults in Himalayas. Hammerl (Geosci Lett 4:7, 2017 introduced historical seismological studies in Austria, starting from methodology which is state of the art in most European countries, followed by a case study for an earthquake of July 17, 1670 in Tyrol. Albini and Rovida (Geosci Lett 3:30, 2016 examined 114 historical records for the earthquake on April 6, 1667 on the east coast of the Adriatic Sea, compiled 37 Macroseismic Data Points, and estimated the epicenter and the size of the earthquake. Matsu’ura (Geosci Lett 4:3, 2017 summarized historical earthquake studies in Japan which resulted in about 8700 Intensity Data Points, assigned epicenters for 214 earthquakes between AD 599 and 1872, and estimated focal depth and magnitudes for 134 events. Wang et al. (Geosci Lett 4:4, 2017 introduced historical seismology in China, where historical earthquake archives include about 15,000 sources, and parametric catalogs include about 1000 historical earthquakes between 2300 BC and AD 1911. Ishibe et al. (Geosci Lett 4:5, 2017 tested the Coulomb stress triggering hypothesis for three giant (M~9 earthquakes that occurred in recent years, and found that at least the 2004 Sumatra–Andaman and 2011 Tohoku earthquakes caused the seismicity rate change. Ishimura (2017 re-estimated the ages of 11 tsunami deposits in the last 4000 years along the Sanriku coast of northern Japan and found that the average recurrence interval of those tsunamis as 350–390 years. Ramos et al. (2017 studied ~ 1000-year-old marine terraces on the west

  4. Effect of treatment of a previous ectopic pregnancy on in vitro fertilization-intracytoplasmic sperm injection outcomes: a retrospective cohort study.

    Science.gov (United States)

    Xu, Zhen; Yan, Lei; Liu, Wen; Xu, Xinxin; Li, Miao; Ding, Lingling; Ma, Jinlong; Chen, Zi-Jiang

    2015-12-01

    To evaluate the influence of previous ectopic pregnancies (EP) and different EP treatment methods on in vitro fertilization-intracytoplasmic sperm injection (IVF-ICSI) outcomes. Retrospective cohort study. University-based reproductive medicine center. Women undergoing 51,268 fresh cycles of IVF-ICSI. In women who had had an EP before the IVF treatment and women who were diagnosed with fallopian disease without an EP (control group), division into three treatment subgroups: subgroup 1, conservative treatment; subgroup 2, salpingostomy; and subgroup 3 salpingectomy. Estimates of IVF-ICSI outcome and ovarian function based on number of antral follicles and rates of implantation, EP, clinical pregnancy, and delivery. For the experimental group and the control group, there were no statistically significant differences in the rates of implantation, clinical pregnancy, or delivery. However, the risk of recurrent EP was statistically significantly higher in the experimental group compared with the control group. There were no statistically significant differences in IVF-ICSI outcomes between the three treatment subgroups in terms of the basic antral follicle number or the dominant antral follicle numbers (>1.0 cm) after surgical treatment of EP. Our results suggest that women with a prior history of EP have a higher recurrence risk of EP after IVF in comparison with women with no history of EP. Previous EP has no effect on the main IVF-ICSI outcomes. For the treatment of EP, salpingostomy and salpingectomy do not statistically significantly affect ovarian function. Copyright © 2015 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  5. Mining geologic study in black san stones in Aguas Dulces, Rocha Province

    International Nuclear Information System (INIS)

    2002-01-01

    On September of the 2002 black san stones deposit were considered Uruguay mining reservation which it last 6 months. They were selected the best deposits areas which were carried out 37 drillings in 727.046 hectare as. The mineralogical composition and uses of Black san stones sampling were analyzed.. Field and laboratory studies were given as methodology. As conclusion they were found 933.000 tons of mineral like ilmenite, zircon, rut ilo, monazite and titanite equivalent to 65% all heavy metals.

  6. Design study on containers for geological disposal of high-level radioactive waste

    International Nuclear Information System (INIS)

    Arup, O.

    1985-01-01

    A study has been made of the requirements and design features for containers to isolate vitrified high-level radioactive waste from the environment for a period of 500 to 1000 years. The requirements for handling, storing and transporting containers have been identified following a study of disposal operations, and the pressures and temperatures which may possibly be experienced in clay, granite and salt formations have been estimated. A range of possible container designs have been proposed to satisfy the requirements of each of the disposal environments. Alternative design concepts in corrosion resistant or corrosion allowance material have been suggested. Some resist pressure by using a structural shell leaving the contents unstressed whereas others transmit loads to their contents. Potentially suitable container shell materials have been selected following a review of corrosion studies and although metals have not been specified in detail, titanium alloys and low carbon steels are thought to be appropriate for corrosion resistant and corrosion allowance designs respectively. Performance requirements for container filler materials have been identified and candidate materials assessed. However, no entirely suitable materials have been found and further research is required in this area. A preliminary container stress analysis has shown the importance of thermal modelling and that if lead is used as a filler it dominates the stress response of the container. Possible methods of manufacturing disposal containers have been assessed and found to be generally feasible although filling operations and container closure could be difficult

  7. Study on detailed geological modelling for fluvial sandstone reservoir in Daqing oil field

    Energy Technology Data Exchange (ETDEWEB)

    Zhao Hanqing; Fu Zhiguo; Lu Xiaoguang [Institute of Petroleum Exploration and Development, Daqing (China)

    1997-08-01

    Guided by the sedimentation theory and knowledge of modern and ancient fluvial deposition and utilizing the abundant information of sedimentary series, microfacies type and petrophysical parameters from well logging curves of close spaced thousands of wells located in a large area. A new method for establishing detailed sedimentation and permeability distribution models for fluvial reservoirs have been developed successfully. This study aimed at the geometry and internal architecture of sandbodies, in accordance to their hierarchical levels of heterogeneity and building up sedimentation and permeability distribution models of fluvial reservoirs, describing the reservoir heterogeneity on the light of the river sedimentary rules. The results and methods obtained in outcrop and modem sedimentation studies have successfully supported the study. Taking advantage of this method, the major producing layers (PI{sub 1-2}), which have been considered as heterogeneous and thick fluvial reservoirs extending widely in lateral are researched in detail. These layers are subdivided into single sedimentary units vertically and the microfacies are identified horizontally. Furthermore, a complex system is recognized according to their hierarchical levels from large to small, meander belt, single channel sandbody, meander scroll, point bar, and lateral accretion bodies of point bar. The achieved results improved the description of areal distribution of point bar sandbodies, provide an accurate and detailed framework model for establishing high resolution predicting model. By using geostatistic technique, it also plays an important role in searching for enriched zone of residual oil distribution.

  8. Micro-CT in situ study of carbonate rock microstructural evolution for geologic CO2 storage

    DEFF Research Database (Denmark)

    Zheng, Yi; Yang, Yan; Rogowska, M.

    2017-01-01

    settings such as the carbonate reservoirs in the North Sea. The final aim of our project is to find out how to control the evolution of petrophysical parameters during CO2 injection using an optimal combination of flow rate, injection pressure and chemical composition of the influent. The first step...... to achieve this is to find a suitable condition to create a stable 3D space in carbonate rock by injecting liquid to prepare space for the later CO2 injection. Micro-CT imaging is a non-destructive 3D method that can be used to study the property changes of carbonate rocks during and after CO2 injection...

  9. Studies of nuclear-waste migration in geologic media. Annual report, October 1977-September 1978

    International Nuclear Information System (INIS)

    Seitz, M.G.; Rickert, P.G.; Fried, S.M.; Friedman, A.M.; Steindler, M.J.

    1979-07-01

    The first phenomenon studied is incomplete water-nuclide-rock reaction because of slow reaction kinetics. A kinetic factor derived from the experimental results for strontium migration through glauconite (a hydrous silicate) was expressed in terms of the linear flow rate of solution and can be used to predict migration due to solution flow at rates of 0 to about 12 cm/min (60 km/y). Continuous-flow infiltration experiments with americium in fissures gave results that are predicted by a migration model that includes kinetic factors measured in experiments with static fluids. The results suggest that kinetic factors are as important as equilibrium adsorption parameters in predicting nuclide migration. The second phenomenon studied was the amount of adsorbed nuclide not being proportional to the nuclide concentration in solution (nonlinear adsorption isotherm). For cesium adsorption on limestone, a nonlinear isotherm was found to occur in the range of initial cesium concentrations from about 10 -3 to 10 -9 M. This adsorption property was confirmed by results of column-infiltration experiments in which cesium migration through oolitic limestone was found to be sensitive to the amount of cesium in solution. The existence of a nonlinear isotherm precludes the use of a single partition value (K/sub D/) to describe cesium migration in limestone at cesium concentrations above about 10 -9 M. Therefore, the effects of nonlinear isotherms are germane to nuclide migration. 24 figures, 6 tables

  10. Results and synthesis of integrated geologic studies of the carboniferous Lisburne Group of Northeastern Alaska. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Watts, K.F.

    1995-05-01

    The primary objective of this project was to develop an integrated database to characterize reservoir heterogeneities resulting from numerous small-scale shallowing-upward cycles (parasequences) comprising the Pennsylvanian Wahoo 1imestone. The Wahoo Limestone is the upper part of an extensive carbonate platform sequence of the Carboniferous Lisburne Group which is widely exposed in the Brooks Range and is a widespread hydrocarbon reservoir unit in the subsurface of the North Slope of Alaska. A leading goal is to determine lateral and vertical variations in the complex mosaic of carbonate facies comprising the Wahoo. Aspects of rock units adjacent to the Wahoo, the underlying Endicott Group and Alapah Limestone and overlying Echooka Formation are also discussed. This report includes an overview of the regional geological framework; a discussion of biostratigraphic results; a summary of diagenetic studies; and preliminary results of comparative studies of a cored well in the Lisburne oil field. A computerized database system (the Wahoo database) was developed and is explained in a users manual. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.

  11. US Geological Survey studies of commercial low-level radioactive waste disposal sites - a summary of results

    International Nuclear Information System (INIS)

    Fischer, J.N.

    1983-01-01

    The US Geological Survey has completed geohydrologic investigations of five commercial low-level, radioactive-waste disposal sites. Final reports on two of the sites have been released and the remaining three will be published this year. A highly permeable glacial sand, originally thought to be discontinuous, has proven to be continuous in narrow channel deposits at the site near Sheffield, Illinois. These deposits have provided pathways for tritium-contaminated ground water to move off site. At another site, near West Valley, New York, the distribution and geohydrologic characteristics of the fine-grained glacial sediments have been studied and documented. Contaminants have not been detected in ground water away from the site. Studies at the Maxey Flats, Kentucky site, indicated that only 0.1 inches of precipitation percolates through bedrock from the site to the valley floor annually. Investigations at the arid Beatty, Nevada site, have been directed toward the geohydrologic characterization of unaturated sediments at the site. A significant finding of geohydrologic investigation of the Barnwell, South Carolina site, was that cobalt 60 in ground water percolating through the bottom of one trench diminished to undetectable levels of concentration within 6 feet of the trench bottom. This fact suggests that soil characteristisc at the site are effective in impending transport of that, and perhaps other, radionuclides. 6 references

  12. Environmental flow studies of the Fort Collins Science Center, U.S. Geological Survey-Cherry Creek, Arizona

    Science.gov (United States)

    Waddle, Terry J.; Bovee, Ken D.

    2010-01-01

    At the request of the U.S. Forest Service, an instream flow assessment was conducted at Cherry Creek, Ariz., to investigate habitat for native and introduced fish species and to describe the beneficial use of a possible instream flow water right. The U.S. Geological Survey (USGS) Fort Collins Science Center performed an intensive field study of two sections of Cherry Creek in September 2008 to provide base data for hydrodynamic simulation of the flow conditions in the stream. The USGS Arizona Cooperative Fish and Wildlife Research Unit, at the University of Arizona School of Natural Resources, conducted a survey of the habitat requirements of the resident fish species in Cherry Creek and provided the habitat suitability criteria used in this study. The habitat suitability criteria were combined with hydrodynamic simulation results to quantify fish habitat for the full range of daily flow experienced in the creek and to produce maps of habitat occurrence for those flows. The flow record at the Cherry Creek stream gage was used to generate habitat response values over time. The long-term habitat response was incorporated into an Excel (Registered) spreadsheet to allow evaluation of habitat occurrence with and without an instream water right under different hypothetical water withdrawal scenarios. The spreadsheet displays information about the time sequence of habitat events, the duration of critical events, and habitat retention.

  13. Hydrologic monitoring and selected hydrologic and environmental studies by the U.S. Geological Survey in Georgia, 2011–2013

    Science.gov (United States)

    Clarke, John S.; Dalton, Melinda J.

    2013-01-01

    This compendium of papers describes results of hydrologic monitoring and hydrologic and environmental studies completed by the U.S. Geological Survey (USGS) in Georgia during 2011–2013. The USGS addresses a wide variety of water issues in the State of Georgia working with local, State, and Federal partners. As the primary Federal science agency for water resource information, the USGS monitors the quantity and quality of water in the Nation’s rivers and aquifers, assesses the sources and fate of contaminants in aquatic systems, collects and analyzes data on aquatic ecosystems, develops tools to improve the application of hydrologic information, and ensures that its information and tools are available to all potential users. During 2011–2013, the USGS continued a long-term program of monitoring stream and groundwater resources, including flow, water quality, and water use. In addition, a variety of hydrologic and environmental studies were completed to assess water availability, hydrologic hazards, and the impact of development on water resources. Information on USGS activities in Georgia is available online at http://ga.water.usgs.gov/.

  14. Two consecutive phase II studies of oxaliplatin (L-OHP) for treatment of patients with advanced colorectal carcinoma who were resistant to previous treatment with fluoropyrimidines.

    Science.gov (United States)

    Machover, D; Diaz-Rubio, E; de Gramont, A; Schilf, A; Gastiaburu, J J; Brienza, S; Itzhaki, M; Metzger, G; N'Daw, D; Vignoud, J; Abad, A; Francois, E; Gamelin, E; Marty, M; Sastre, J; Seitz, J F; Ychou, M

    1996-01-01

    Oxaliplatin (L-OHP) is a platinum complex that possesses activity against human and murine cells in vitro and in vivo, including colorectal carcinoma-derived cell lines, and cells that have been selected for resistance to cisplatin. We report two consecutive phase II trials of L-OHP for treatment of patients with advanced colorectal carcinoma. Fifty-eight patients were entered in study I, and 51 patients in study II. All of the patients had tumor progression when they were treated, prior to their enrollment, with a fluoropyrimidine-containing regimen. In both trials treatment consisted of L-OHP, 130 mg/m2, by i.v. infusion for two hours; the treatment was repeated every 21 days. Response to therapy: Study I: Fifty-five patients were assessed for response. The response rate was 11% (95% CI, 0.03-0.19). Study II: All 51 patients were assessed for response. The response rate was 10% (95% CI, 0.017-0.18). The overall response rate for the 106 evaluated patients was 10% (95% CI, 0.046-0.16). Times to disease progression in responders were 4, 4, 4.5+, 5, 5, 6, 6, 6, 6+, 9, and 13 months. The dose-limiting toxic effect was sensory peripheral neuropathy. The incidence of severe peripheral neuropathy grades was: Study I: grade 3, 23% of patients, and grade 4, 8% of patients. Severe neuropathy had a favorable course in all of the patients who had long-term neurologic follow-up. Diarrhea and myeloid impairment were minor. L-OHP produced modest, but definite antitumor activity in patients with advanced colorectal carcinoma who were previously resistant to chemotherapy including fluoropyrimidines. Toxicity is within acceptable limits of tolerance at the dose and schedule of oxaliplatin used in this trial.

  15. Geology Data Package for the Single-Shell Tank Waste Management Areas at the Hanford Site

    Energy Technology Data Exchange (ETDEWEB)

    Reidel, Steve P.; Chamness, Mickie A.

    2007-01-01

    This data package discusses the geology of the single-shell tank (SST) farms and the geologic history of the area. The focus of this report is to provide the most recent geologic information available for the SST farms. This report builds upon previous reports on the tank farm geology and Integrated Disposal Facility geology with information available after those reports were published.

  16. Coastal submarine springs in Lebanon and Syria: Geological, Geochemical, and Radio-isotopic study

    International Nuclear Information System (INIS)

    Al-Charideh, A.

    2005-01-01

    The coastal karst aquifer system (Upper Cretaceous) and the submarine springs in the Syrian coast have been studied using chemical and isotopic methods in order to determine the hydraulic connections between the groundwater and the submarine springs. Results show that the groundwater and submarine springs are having the same slope on the δ 18 O/δ 2 H plot indicate the same hydrological origin for both. In addition this relation is very close to the Local Meteoric Water Line (LMWL) reflecting a rapid infiltration of rainfall to recharge coastal aquifer. The calculated percentage of freshwater in the two locations (Bassieh and Tartous) range from 20 to 96%. The estimation rate of the permanent submarines springs (BS1, BS2 and TS2, TS3) is 11m 3 /s or 350 million m 3 /y. The maximum residence time of the groundwater in the Cenomanian/Turonian aquifer was estimated at around 8 years, using the piston-flow model. (Author)

  17. U.S. Geological Survey - Virginia Department of Transportation: Bridge scour pilot study

    Science.gov (United States)

    Austin, Samuel H.

    2018-02-27

    BackgroundCost effective and safe highway bridge designs are required to ensure the long-term sustainability of Virginia’s road systems. The streamflows that, over time, scour streambed sediments from bridge piers inherently affect bridge safety and design costs. To ensure safety, bridge design must anticipate streambed scour at bridge piers over the lifespan of a bridge. Until recently Federal Highway Administration (FHWA) guidance provided only for scour estimates of granular, noncohesive, highly erosive material yielding overestimates of scour potential in instances when streambed materials offer some resistance to scour. This study seeks to estimate stream power and streambed scour for these more resistive sites, with bridge piers potentially established in cohesive soil or erodible rock. This new knowledge may provide significant construction cost savings while ensuring design and construction of safe highway bridges.

  18. Drilling techniques presently in use by the Geothermal Studies Project, US Geological Survey

    Energy Technology Data Exchange (ETDEWEB)

    Moses, T.H. Jr.; Sass, J.H.

    1979-01-01

    The heat-flow studies program has evolved from one in which holes drilled for other purposes (mining and oil exploration, nuclear tests, hydrologic studies, etc.) provided the bulk of the data to a program in which the free holes, while still providing cost-effective and useful data, are being supplemented increasingly by holes drilled specifically for heat-flow determinations at locations where thermal data of high quality are needed, and where nobody else is interested in drilling. Ideally, heat-flow holes should be located in areas with moderate local relief and should be completed so that vertical water movement is inhibited. The most satisfactory test media for heat-flow determinations are crystalline rocks (particularly granites) and unconsolidated sediments; carbonate rocks and volcanic terranes can provide useful heat-flow data, but they present greater challenges both in drilling and interpretation. Drilling techniques have evolved from that of the continuously cored diamond-drilled hole (adapted from mining exploration) to adaptations of the shot-hole and blast-hole techniques used in petroleum exploration, water-well construction, and quarry operations. Spot cores are obtained where necessary to provide specific petrologic, geochemical, and physical data, but primary reliance is placed on ditch samples from rotary or percussion drilling for routine measurements of thermal conductivity and heat production. In shallow (50 to 100 m) holes in low temperature environments, plastic casing is used to maintain access for later temperature measurements. For deeper holes, steel casing is preferred. The annulus between casing and borehole wall in the lowermost 50 to 80 meters of heat-flow holes is routinely grouted off with a specially designed mixture of cement, bentonite, salt, and water to prevent vertical water movement.

  19. Potential for geological sequestration of CO{sub 2} in Switzerland - Final report; Studie zur Abschaetzung des Potenzials fuer CO{sub 2}-Sequestrierung in der Schweiz - Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Diamond, L. W.; Chevalier, G. [Institut fuer Geologie, Universitaet Bern, Bern (Switzerland); Leu, W. [Geoform AG, Geologische Beratungen und Studien, Villeneuve (former Minusio) (Switzerland)

    2010-08-15

    One approach to dispose of the greenhouse gas CO{sub 2} is to inject it into deep, porous geological formations, where is remains safely trapped over periods of many millennia. This report evaluates the potential for this option within Switzerland, based on a literature review. Only geological criteria for CO{sub 2} sequestration are taken into account, following international best-practice principles for reservoir safety. Simultaneous consideration of nine geological attributes (including faulting and natural seismicity) allows the sequestration potential to be mapped at a resolution of a few km{sup 2}, using a scale between 0 (negligible potential) and 1 (high potential). It is concluded that the crystalline rocks of the Alps and the sediments underlying the valleys of Valais, Ticino and Grisons are unsuitable for CO{sub 2} sequestration. However, the sedimentary rocks below the Central Plateau (and to lesser extent below the Jura Chain), locally show moderate to very good potential. At least four formations of porous sandstones and limestones (saline aquifers) underlie large areas of the Plateau within the technically favoured depth interval of 800-2500 m. Approximately 5000 km{sup 2} of the Plateau (mostly in the sector Fribourg-Olten-Lucerne) exhibits sequestration potentials above 0.6, offering a theoretical (unproven) storage capacity for approximately 2680 million tonnes of CO{sub 2}. From a purely geological point of view these results are promising. Although the high potentials do not guarantee the feasibility of CO{sub 2} sequestration, they serve as guides to areas that warrant detailed investigation. If this CO{sub 2} storage option is pursued in Switzerland, then more detailed geological investigations and a pilot study would be necessary to prove its feasibility. The assessed risks, leakage-monitoring procedures and non-geological criteria (proximity to CO{sub 2} point-sources, economics, conflicts of use of the subsurface, etc.) would have to be

  20. Two-step web-mining approach to study geology/geophysics-related open-source software projects

    Science.gov (United States)

    Behrends, Knut; Conze, Ronald

    2013-04-01

    Geology/geophysics is a highly interdisciplinary science, overlapping with, for instance, physics, biology and chemistry. In today's software-intensive work environments, geoscientists often encounter new open-source software from scientific fields that are only remotely related to the own field of expertise. We show how web-mining techniques can help to carry out systematic discovery and evaluation of such software. In a first step, we downloaded ~500 abstracts (each consisting of ~1 kb UTF-8 text) from agu-fm12.abstractcentral.com. This web site hosts the abstracts of all publications presented at AGU Fall Meeting 2012, the world's largest annual geology/geophysics conference. All abstracts belonged to the category "Earth and Space Science Informatics", an interdisciplinary label cross-cutting many disciplines such as "deep biosphere", "atmospheric research", and "mineral physics". Each publication was represented by a highly structured record with ~20 short data attributes, the largest authorship-record being the unstructured "abstract" field. We processed texts of the abstracts with the statistics software "R" to calculate a corpus and a term-document matrix. Using R package "tm", we applied text-mining techniques to filter data and develop hypotheses about software-development activities happening in various geology/geophysics fields. Analyzing the term-document matrix with basic techniques (e.g., word frequencies, co-occurences, weighting) as well as more complex methods (clustering, classification) several key pieces of information were extracted. For example, text-mining can be used to identify scientists who are also developers of open-source scientific software, and the names of their programming projects and codes can also be identified. In a second step, based on the intermediate results found by processing the conference-abstracts, any new hypotheses can be tested in another webmining subproject: by merging the dataset with open data from github

  1. Subsurface geology of the Lusi region: preliminary results from a comprehensive seismic-stratigraphic study.

    Science.gov (United States)

    Moscariello, Andrea; Do Couto, Damien; Lupi, Matteo; Mazzini, Adriano

    2016-04-01

    We investigate the subsurface data of a large sector in the Sidoarjo district (East Java, Indonesia) where the sudden catastrophic Lusi eruption started the 26th May 2006. Our goal is to understand the stratigraphic and structural features which can be genetically related to the surface manifestations of deep hydrothermal fluids and thus allow us to predict possible future similar phenomena in the region. In the framework of the Lusi Lab project (ERC grant n° 308126) we examined a series of densely spaced 2D reflection commercial seismic lines This allowed the reconstruction of the lateral variability of key stratigraphic horizons as well as the main tectonic features. In particular, we shed light on the deep structure of the Watukosek fault system and the associated fracture corridors crossing the entire stratigraphic successions. To the South-West, when approaching the volcanic complex, we could identify a clear contrast in seismic facies between chaotic volcanoclastic wedges and clastic-prone sedimentary successions as well as between the deeper stratigraphic units consisting of carbonates and lateral shales units. The latter show possible ductile deformation associated to fault-controlled diapirism which control in turns deformation of overlying stratigraphic units and deep geo-fluids circulation. Large collapse structures recognized in the study area (e.g. well PRG-1) are interpreted as the results of shale movement at depth. Similarly to Lusi, vertical deformation zones ("pipes"), likely associated with deeply rooted strike-slip systems seem to be often located at the interface between harder carbonate rocks forming isolated build ups and the laterally nearby clastic (shale-prone)-units. The mechanisms of deformation of structural features (strike vs dip slip systems) which may affect either the basement rock or the overlying deeper stratigraphic rocks is also being investigated to understand the relationship between deep and shallower (i.e. meteoric) fluid

  2. Consolidation of geologic studies of geopressured geothermal resources in Texas. 1982 annual report

    Energy Technology Data Exchange (ETDEWEB)

    Morton, R.A.; Ewing, T.E.; Kaiser, W.R.; Finley, R.J.

    1983-03-01

    Detailed structural mapping at several horizons in selected study areas within the Frio growth-fault trend demonstrates a pronounced variability in structural style. At Sarita in South Texas, shale mobilization produced one or more shale ridges, one of which localized a low-angle growth fault trapping a wedge of deltaic sediments. At Corpus Christi, shale mobilization produced a series of large growth faults, shale-cored domed anticlines, and shale-withdrawal basins, which become progressively younger basinward. At Blessing, major growth faults trapped sands of the Greta/Carancahua barrier system with little progradation. At Pleasant Bayou, a major early growth-fault pattern was overprinted by later salt tectonics - the intrusion of Danbury Dome and the development of a salt-withdrawal basin. At Port Arthur, low-displacement, long-lived faults formed on a sand-poor shelf margin contemporaneously with broad salt uplifts and basins. Variability in styles is related to the nature and extent of Frio sedimentation and shelf-margin progradation and to the presence or absence of salt. Structural styles that are conducive to the development of large geothermal reservoirs include blocks between widely spaced growth faults having dip reversal, salt-withdrawal basins, and shale-withdrawal basins. These styles are widespread on the Texas Gulf Coast. However, actually finding a large reservoir depends on demonstrating the existence of sufficient sandstone with adequate quality to support geopressured geothermal energy production.

  3. Feasibility study for automation of the Central Laboratories, Water Resources Division, U.S. Geological Survey

    International Nuclear Information System (INIS)

    Morris, W.F.; Peck, E.S.; Fisher, E.R.; Barton, G.W. Jr.

    1976-01-01

    This study of the feasibility of further automating the Central Laboratories deals specifically with the combined laboratory operations in Salt Lake City, Utah, and Denver, Colorado and is prepared with the understanding that such a system will also be implemented at the Central Laboratories in Atlanta, Georgia, and Albany, New York. The goals of automation are defined in terms of the mission of a water analysis laboratory, propose alternative computer systems for meeting such goals, and evaluate these alternatives in terms of cost effectiveness and other specified criteria. It is found that further automation will be beneficial and an in-house system that incorporates dual minicomputers is recommended: one for time-shared data acquisition, processing, and control; the second for data management. High-use analytical instruments are placed on-line to the time-shared minicomputer, with a terminal at each instrument and backup data storage on magnetic tape. A third, standby computer is switched in manually should the time-shared computer go down. Field-proven, modular hardware and software are chosen. Also recommended is the incorporation of the highly developed, computer-integrated instruments that are commercially available for determining petrochemicals and other organic substances, and are essential to the Laboratories' mission

  4. Study of crustal structure and geological implications of southwestern margin of Northeast India

    Science.gov (United States)

    Saikia, Sowrav; Baruah, Santanu; Chopra, Sumer; Singh, Upendra K.; Gogoi, Bibhuti; Gohain, Himanata B.

    2018-01-01

    It is noticed that few geophysical studies have been carried out to decipher the crustal structure of southwestern part of the Northeast India comprising of Tripura fold belt and Bengal basin as compared to the Shillong plateau and the Brahmaputra basin. This region has a long history of seismicity that is still continuing. We have determined first-order crustal features in terms of Moho depths ( H) and average VP/VS ratios ( κ) using H- κ stacking technique. The inversion of receiver functions data yields near surface thick sedimentary layer in the Bengal basin, which is nearly absent in the Shillong plateau and Tripura fold belt. Our result suggests that the crust is thicker (38-45 km) in the Tripura fold belt region with higher shear-wave velocity in the lower crust than the Shillong plateau. The distribution of VP/VS ratio indicates heterogeneity throughout the whole region. While low to medium value of Poisson's ratio (1.69-1.75) indicates the presence of felsic crust in the Shillong plateau of the extended Indian Archean crust. The medium to high values of VP/VS ratio (> 1.780) in the Bengal basin and the Tripura fold belt region represent mafic crust during the formation of the Bengal delta and the Tripura fold belt creation in the Precambrian to the Permian age. The depth of the sediments in the Bengal basin is up to 8 km on its eastern margin, which get shallower toward its northeastern and southeastern margins.

  5. A study on the radionuclide transport by bacteria in geologic media

    International Nuclear Information System (INIS)

    Han, Byoung Sub

    1997-02-01

    The purpose of this paper is to provide a methodology to develop a predictive model based on a conceptual three phase system and to investigate the influence of bacteria and their generation on the transport of radionuclide in porous and fractured media. The mass balance for bacteria, substrate and radionuclide were formulated. To illustrate the model simply, an equilibrium condition was assumed to partition the substrate, bacteria and radionuclide concentrations between the solid soil matrix, aqueous phase, rock matrix and bacterial surface. From the numerical calculation of the radionuclide transport in the presence of bacteria, it was found that the growth of bacteria and supplied primary substrate as limiting or stimulating growth factor of bacteria are the most important factors of the radionuclide transport. We also found that, depend on the transport of bacteria the temporal and spatial distribution of radionuclide concentration was significantly altered. The model proposed in this study will improve the evaluation of the role of the bacteria in the transport of radionuclide in groundwater systems. Furthermore, this model would be usefully utilized in analyzing the important role of colloidal particulate on the overall performance of radioactive waste safety

  6. Geological remote sensing

    Science.gov (United States)

    Bishop, Charlotte; Rivard, Benoit; de Souza Filho, Carlos; van der Meer, Freek

    2018-02-01

    Geology is defined as the 'study of the planet Earth - the materials of which it is made, the processes that act on these materials, the products formed, and the history of the planet and its life forms since its origin' (Bates and Jackson, 1976). Remote sensing has seen a number of variable definitions such as those by Sabins and Lillesand and Kiefer in their respective textbooks (Sabins, 1996; Lillesand and Kiefer, 2000). Floyd Sabins (Sabins, 1996) defined it as 'the science of acquiring, processing and interpreting images that record the interaction between electromagnetic energy and matter' while Lillesand and Kiefer (Lillesand and Kiefer, 2000) defined it as 'the science and art of obtaining information about an object, area, or phenomenon through the analysis of data acquired by a device that is not in contact with the object, area, or phenomenon under investigation'. Thus Geological Remote Sensing can be considered the study of, not just Earth given the breadth of work undertaken in planetary science, geological features and surfaces and their interaction with the electromagnetic spectrum using technology that is not in direct contact with the features of interest.

  7. The priming effect of previous natural pandemic H1N1 infection on the immunogenicity to subsequent 2010-2011 influenza vaccination in children: a prospective cohort study.

    Science.gov (United States)

    Kang, Eun Kyeong; Eun, Byung Wook; Kim, Nam Hee; Lim, Jung Sub; Lee, Jun Ah; Kim, Dong Ho

    2016-08-22

    The effect of previous natural pandemic H1N1 (H1N1 pdm09) influenza infection on the immunogenicity to subsequent inactivated influenza vaccination in children has not been well studied. We aimed to evaluate the effect of H1N1 pdm09 natural infection and vaccination on the immunogenicity to subsequent 2010-2011 seasonal inactivated influenza vaccination in children. From October 2010 to May 2011, we conducted an open-label, multi-center study in children aged 6 months -18 years in Korea. We measured antibody titers with a hemagglutination-inhibition (HI) assay at baseline, 1 month, and 6 months after vaccination with trivalent split or subunit vaccines containing H1N1 pdm, A/H3N2, and B. The subjects were classified into 4 groups depending on the presence of laboratory-confirmed H1N1 pdm09 infection and/or vaccination in the 2009-2010 season; Group I: vaccination (-)/infection(-), Group II: vaccination (-)/infection(+), Group III: vaccination (+)/infection(-), Group IV: vaccination (+)/infection(+). Among the subjects in group I, 47 subjects who had a baseline titer >1:10 were considered to have an asymptomatic infection. They were included into the final group II (n = 80). We defined the new group II as the infection-primed (IP) group and group III as the vaccine-primed (VP) group. Seroconversion rate (57.5 % vs 35.9 %, p = 0.001), seroprotection rate at 6 months after vaccination (70.8 % vs 61.8 %, p = 0.032), and GMT at 1 month after vaccination (129.9 vs 66.5, p = 0.002) were significantly higher in the IP group than in the VP group. In the 9-18 year-old group, seroconversion rate and immunogenicity at 1 and 6 months were significantly higher in the IP group than in the VP group. However in the 1-7 year-old age group, there was no significant difference between the two groups. Previous H1N1 pdm09 infection appears to have positive effects on immunogenicity of subsequent inactivated influenza vaccines against H1N1 pdm09 in older

  8. Coal and petroleum resources in the Appalachian basin: index maps of included studies: Chapter B.1 in Coal and petroleum resources in the Appalachian basin: distribution, geologic framework, and geochemical character

    Science.gov (United States)

    Ruppert, Leslie F.; Trippi, Michael H.; Kinney, Scott A.; Ruppert, Leslie F.; Ryder, Robert T.

    2014-01-01

    This chapter B.1 of U.S. Geological Survey (USGS) Professional Paper 1708 provides index maps for many of the studies described in other chapters of the report. Scientists of the USGS and State geological surveys studied coal and petroleum resources in the central and southern Appalachian structural basins. In the southern Appalachian basin, studies focused on the coal-bearing parts of the Black Warrior basin in Alabama. The scientists used new and existing geologic data sets to create a common spatial geologic framework for the fossil-fuel-bearing strata of the central Appalachian basin and the Black Warrior basin in Alabama.

  9. Off-platform Silurian sequences in the Ambler River quadrangle: A section in Geologic studies in Alaska by the U.S. Geological Survey during 1987

    Science.gov (United States)

    Dumoulin, Julie A.; Harris, Anita G.

    1988-01-01

    Lithofacies changes in coeval upper Paleozoic rocks have been used to unravel the tectonic history of northern Alaska (for example, Mayfield and others, 1983). Conodont biostratigraphy and detailed petrologic studies are now revealing facies differences in lower Paleozoic rocks that can also be used to constrain their tectono-sedimentary framework (Dumoulin and Harris, 1987). A basic element of basin analysis is the discrimination of shallow-water shelf and platform sequences from deeper water slope and basinal deposits. This report documents several new localities of deeper water, off-platform Silurian deposits in the Ambler River quadrangle and briefly outlines some of their paleogeographic implications.

  10. Using Accretionary Hard Parts to Study Changes in Seasonality over Geologic Time

    Science.gov (United States)

    Ivany, L. C.; Judd, E. J.

    2017-12-01

    Seasonality has been an enigma for deep-time research. Proxies for mean annual temperature (MAT) are the mainstay of paleoclimate studies, and while these are tremendously informative, seasonal extremes are the variables that matter most for many paleoclimatic, paleoceanographic, and physiologic processes. Seasonality has been difficult to constrain in the rock record, however, because of the need for subannual resolution - very few such archives exist. One of the most promising comes in the form of the mineralized hard parts of organisms that grow by accretion, e.g., mollusks, corals, fish otoliths. Such materials carry a chemical signature of temperature at the time of precipitation, allowing for assessment of the seasonal temperature extremes experienced by the organism. Interpretation of these records in the context of climate, however, are complicated by the overprint of biology - organisms don't necessarily grow all year long, resulting in a truncation of the seasonal cycle regardless of sampling resolution. Furthermore, unrecognized differences in depositional environment or taxon ecology among samples can make comparisons over time even more tenuous. Even with internally consistent datasets, assessment of pattern is rarely based on more than visual inspection. An iterative computational procedure predicated on the assumption of sinusoidal variation in temperature and growth rate can circumvent these concerns. Deviations in the shape of oxygen isotope profiles from the predicted sinusoid allow recovery of the mean and amplitude of temperature variation as well as the timing and duration of growth within years. Estimates of such parameters from multiple specimens allow for meaningful comparisons over time, both for seasonality and the growth response of organisms. We apply this approach to datasets of seasonal variation through the Paleogene of the US Gulf Coastal Plain and the Eocene of Antarctica derived largely from marine bivalve mollusks. In the

  11. Geological interpretation of cone penetrometer tests in Norton Sound, Alaska

    Science.gov (United States)

    Hampton, M.A.; Lee, H.J.; Beard, R.M.

    1982-01-01

    In situ cone-penetrometer tests at 11 stations in Norton Sound, Alaska, complement previous studies of geologic processes and provide geotechnical data for an analysis of sediment response to loading. Assessment of the penetrometer records shows that various geologic factors influence penetration resistance. On the Yukon prodelta, penetration resistance increases with the level of storm wave or ice loading. In central and eastern Norton Sound, thermogenic and biogenic gas, as well as variations in sediment texture and composition, effect a wide range of resistance to penetration. ?? 1982 A. M. Dowden, Inc.

  12. Geological studies of the COST GE-1 well, United States South Atlantic outer continental shelf area

    Science.gov (United States)

    Scholle, Peter A.

    1979-01-01

    The COST No. GE-1 well is the first deep stratigraphic test to be drilled in the southern part of the U.S. Atlantic Outer Continental Shelf (AOCS) area. The well was drilled within the Southeast Georgia Embayment to a total depth of 13,254 ft (4,040 m). It penetrated a section composed largely of chalky limestones to a depth of about 3,300 ft (1,000 m) below the drill platform. Limestones and calcareous shales with some dolomite predominate between 3,300 and 7,200 ft (1,000 and 2,200 m), whereas interbedded sandstones and shales are dominant from 7,200 to 11,000 ft (2,200 to 3,350 m). From 11,000 ft (3,350 m) to the bottom, the section consists of highly indurated to weakly metamorphosed pelitic sedimentary rocks and meta-igneous flows or intrusives. Biostratigraphic examination has shown that the section down to approximately 3,500 ft (1,060 m) is Tertiary, the interval from 3,500 to 5,900 ft (1,060 to 1,800 m) is Upper Cretaceous, and the section from 5,900 to 11,000 ft (1,800 to 3,350 m) is apparently Lower Cretaceous. The indurated to weakly metamorphosed section below 11,000 ft (3,350 m) is barren of fauna or flora but is presumed to be Paleozoic based on radiometric age determinations. Rocks deposited at upper-slope water depths were encountered in the Upper Cretaceous, Oligocene, and Miocene parts of the section. All other units were deposited in outer-shelf to terrestrial environments. Examination of cores, well cuttings, and electric logs shows that potential hydrocarbon-reservoir units are present within the chalks in the uppermost part of the section as well as in sandstone beds to a depth of at least 10,000 ft (3,000 m). Sandstones below that depth, and the metamorphic section between 11,000 and 13.250 ft (3,350 and 4,040 m) have extremely low permeabilities and are unlikely to contain potential reservoir rock. Studies of organic geochemistry, vitrinite reflectance, and color alteration of visible organic matter indicate that the chalk section down to

  13. 3D Geological Model for "LUSI" - a Deep Geothermal System

    Science.gov (United States)

    Sohrabi, Reza; Jansen, Gunnar; Mazzini, Adriano; Galvan, Boris; Miller, Stephen A.

    2016-04-01

    Geothermal applications require the correct simulation of flow and heat transport processes in porous media, and many of these media, like deep volcanic hydrothermal systems, host a certain degree of fracturing. This work aims to understand the heat and fluid transport within a new-born sedimentary hosted geothermal system, termed Lusi, that began erupting in 2006 in East Java, Indonesia. Our goal is to develop conceptual and numerical models capable of simulating multiphase flow within large-scale fractured reservoirs such as the Lusi region, with fractures of arbitrary size, orientation and shape. Additionally, these models can also address a number of other applications, including Enhanced Geothermal Systems (EGS), CO2 sequestration (Carbon Capture and Storage CCS), and nuclear waste isolation. Fractured systems are ubiquitous, with a wide-range of lengths and scales, making difficult the development of a general model that can easily handle this complexity. We are developing a flexible continuum approach with an efficient, accurate numerical simulator based on an appropriate 3D geological model representing the structure of the deep geothermal reservoir. Using previous studies, borehole information and seismic data obtained in the framework of the Lusi Lab project (ERC grant n°308126), we present here the first 3D geological model of Lusi. This model is calculated using implicit 3D potential field or multi-potential fields, depending on the geological context and complexity. This method is based on geological pile containing the geological history of the area and relationship between geological bodies allowing automatic computation of intersections and volume reconstruction. Based on the 3D geological model, we developed a new mesh algorithm to create hexahedral octree meshes to transfer the structural geological information for 3D numerical simulations to quantify Thermal-Hydraulic-Mechanical-Chemical (THMC) physical processes.

  14. A prospective flexible-dose study of paliperidone palmitate in nonacute but symptomatic patients with schizophrenia previously unsuccessfully treated with oral antipsychotic agents.

    Science.gov (United States)

    Schreiner, Andreas; Bergmans, Paul; Cherubin, Pierre; Keim, Sofia; Rancans, Elmars; Bez, Yasin; Parellada, Eduard; Carpiniello, Bernardo; Vidailhet, Pierre; Hargarter, Ludger

    2014-10-01

    The goal of this study was to explore the tolerability, safety, and treatment response of flexible doses of once-monthly paliperidone palmitate (PP) in the subset of nonacute but symptomatic adult patients with schizophrenia previously unsuccessfully treated with oral antipsychotic agents in the PALMFlexS (Paliperidone Palmitate Flexible Dosing in Schizophrenia) study. This was an interventional, single-arm, international, multicenter, unblinded, 6-month study performed in patients with schizophrenia. Patients were categorized according to reasons for switching. In patients switching because of lack of efficacy or for other reasons, primary efficacy outcomes were the proportion achieving treatment response (defined as ≥20% improvement in Positive and Negative Syndrome Scale [PANSS] total score from baseline to last-observation-carried-forward end point) and maintained efficacy (defined as noninferiority in the change in PANSS total score at end point versus baseline [Schuirmann's test]), respectively. A total of 593 patients (intention-to-treat population) were enrolled: 63.1% were male; their mean (SD) age was 38.4 (11.8) years; and 78.6% had paranoid schizophrenia. The main reasons for transition to PP were patient's wish (n = 259 [43.7%]), lack of efficacy (n = 144 [24.3%]), lack of compliance (n = 138 [23.3%]), and lack of tolerability (n = 52 [8.8%]) with the previous oral antipsychotic medication. The recommended PP initiation regimen (150 milligram equivalents [mg eq] day 1 and 100 mg eq day 8) was administered in 93.9% of patients. Mean PANSS total score decreased from 71.5 (14.6) at baseline to 59.7 (18.1) at end point (mean change, -11.7 [15.9]; 95% CI, -13.0 to -10.5; P < 0.0001). Sixty-four percent of patients showed an improvement of ≥20% in PANSS total score, and the percentage of patients rated mildly ill or less in Clinical Global Impression-Severity increased from 31.8% to 63.2%. Mean personal and social performance total score (SD) increased

  15. Safety and tolerability of frovatriptan in the acute treatment of migraine and prevention of menstrual migraine: Results of a new analysis of data from five previously published studies.

    Science.gov (United States)

    MacGregor, E Anne; Pawsey, Stephen P; Campbell, John C; Hu, Xiaojun

    2010-04-01

    Triptans are a recommended first-line treatment for moderate to severe migraine. Using clinical trial data, we evaluated the safety and tolerability of frovatriptan as acute treatment (AT) and as short-term preventive (STP) therapy for menstrual migraine (MM). Data from 2 Phase III AT trials (AT1: randomized, placebo controlled, 1 attack; AT2: 12-months, noncomparative, open label) and 3 Phase IIIb STP trials in MM (MMP1 and MMP2: randomized, placebo controlled, double blind, 3 perimenstrual periods; MMP3: open label, noncomparative, 12 perimenstrual periods) were analyzed. In AT1, patients treated each attack with frovatriptan 2.5 mg, sumatriptan 100 mg, or placebo. In AT2, they used frovatriptan 2.5 mg. In MMP1 and MMP2, women administered frovatriptan 2.5 mg for 6 days during the perimenstrual period, taking a loading dose of 2 or 4 tablets on day 1, followed by once-daily or BID frovatriptan 2.5 mg, respectively; in MMP3, they used BID frovatriptan 2.5 mg. In AT1, which was previously published in part, group differences in adverse events (AEs) were analyzed using the Fisher exact test, and response rates were compared using logistic regression. Post hoc analyses of sustained pain-free status with no AEs (SNAE) and sustained pain response with no AEs (SPRNAE) were performed using a 2-sample test for equality of proportions without continuity correction. For AT2 and the STP studies, data were summarized using descriptive statistics. Results of individual safety analyses for the STP studies were previously reported; the present report includes new results from a pooled analysis of MMP1 and MMP2 and a new analysis of MMP3 in which AEs were coded using Medical Dictionary for Regulatory Activities version 8.0. AT1 included 1206 patients in the safety group; AT2 included 496. In the STP studies, safety data were collected for 1487 women. In AT1 and AT2, 85.6% and 88.3%, respectively, of enrolled patients were women. Overall, AEs were generally mild to moderate (AT

  16. Preliminary study on the three-dimensional geoscience information system of high-level radioactive waste geological disposal

    International Nuclear Information System (INIS)

    Li Peinan; Zhu Hehua; Li Xiaojun; Wang Ju; Zhong Xia

    2010-01-01

    The 3D geosciences information system of high-level radioactive waste geological disposal is an important research direction in the current high-level radioactive waste disposal project and a platform of information integration and publishing can be used for the relevant research direction based on the provided data and models interface. Firstly, this paper introduces the basic features about the disposal project of HLW and the function and requirement of the system, which includes the input module, the database management module, the function module, the maintenance module and the output module. Then, the framework system of the high-level waste disposal project information system has been studied, and the overall system architecture has been proposed. Finally, based on the summary and analysis of the database management, the 3D modeling, spatial analysis, digital numerical integration and visualization of underground project, the implementations of key functional modules and the platform have been expounded completely, and the conclusion has been drawn that the component-based software development method should be utilized in system development. (authors)

  17. NATO Advanced Study Institute on Mixed-Valence Compounds : Theory and Applications in Chemistry, Physics, Geology, and Biology

    CERN Document Server

    1980-01-01

    It has been a decade since two seminal reviews demonstrated that mixed-valence compounds share many unique and fascinating features. The insight pro­ vided by those early works has promoted a great deal of both experimental and theoretical study. As a result of extensive efforts, our understanding of the bonding and properties of mixed-valence compounds has advanced substantially. There has been no compre­ hensive treatment of mixed-valence compounds since 1967, and the meeting convened at Oxford in September, 1979, provided a unique opportunity to examine the subject and its many ramifications. Mixed-valence compounds play an important role in many fields. Although the major impact of the subject has been in chemistry, its importance has become increasingly clear in solid state physics, geology, and biology. Extensive interest and effort in the field of molecular metals has demonstrated that mixed-valency is a prerequisite for high elec­ trical conductivity. The intense colors of many minerals have been s...

  18. Geology, Petrography, Geochemistry and Radioactivity Studies on The Dyke Swarms of Gabal Al Aglab area, North Eastern Desert, Egypt

    International Nuclear Information System (INIS)

    Eldabe, M.M.M.

    2016-01-01

    Gabal Al Aglab area is located in the North Eastern Desert of Egypt bounded by lat. 27° 14'-27° 19' N and long. 33° 00'-33° 05' E. It is covered by pan African basement rocks. The present study concern with the geology, petrography, geochemistry and radioactivity of various types of the dyke swarms in Gabal Al Aglab area. The field studies revealed that the area comprises the following litho-tectonic units ; Dokhan volcanic (oldest) and Hamammat sedimentary rocks and younger granites are represented by both Gabal Um Twier and Gabal Al Aglab syenogranites (youngest). Many dykes of acidic, intermediate and basic composition have a large extension and dissect all the mentioned rock units. The dyke swarms intruding Gabal Al Aglab area include the acidic (felsite and granite porphyry) dykes, while the intermediate comprise andesite and andesite porphyry and the basic dykes show basalt and dolerites. The chronologic relations of these dykes indicate the following sequence of emplacement beginning with the oldest acidic, followed by intermediate and then basic ones. The geochemical studies indicate that the acidic dykes were derived from a highly differentiated calc- alkaline magma, while the basic and intermediate dykes were developed from magma of subalkaline nature. The dykes were derived from separate magmas and not by magmatic differentiation of single mother magma. The radioactivity of the studied dyke rocks revealed that the high levels of radioactivity mainly linked to the acidity, differentiation and alkalinity characters. Radioactive granitic spot was observed along the contact with some basic dykes due to their thermal effect during its emplacement on the granite, at the northern part of the studied area. This radioactive spot display anomalies with higher values in U and Th contents, than the normal background value of the younger granite.

  19. In vitro evaluation of oestrogenic/androgenic activity of the serum organochlorine pesticide mixtures previously described in a breast cancer case–control study

    International Nuclear Information System (INIS)

    Rivero, Javier; Luzardo, Octavio P.; Henríquez-Hernández, Luis A.; Machín, Rubén P.; Pestano, José; Zumbado, Manuel; Boada, Luis D.; Camacho, María; Valerón, Pilar F.

    2015-01-01

    Some organochlorine pesticides (OCs) have been individually linked to breast cancer (BC) because they exert oestrogenic effects on mammary cells. However, humans are environmentally exposed to more or less complex mixtures of these organochlorines, and the biological effects of these mixtures must be elucidated. In this work we evaluated the in vitro effects exerted on human BC cells by the OC mixtures that were most frequently detected in two groups of women who participated in a BC case–control study developed in Spain: healthy women and women diagnosed with BC. The cytotoxicity, oestrogenicity, and androgenicity of the most prevalent OC mixtures found in healthy women (H-mixture) and in BC patients (BC-mixture) were tested at concentrations that resembled those found in the serum of the evaluated women. Our results showed that both OC mixtures presented a similar oestrogenic activity and effect on cell viability, but BC-mixture showed an additional anti-androgenic effect. These results indicate that although the proliferative effect exerted by these mixtures on human breast cells seems to depend mainly on their oestrogenic action, the BC-mixture might additionally induce cell proliferation due to its anti-androgenic activity, therefore increasing the carcinogenic potential of this mixture. The findings of this study demonstrate that subtle variations in the composition of a mixture may induce relevant changes in its biological action. - Highlights: • E-screen and A-screen of two mixtures of organochlorine pesticides (OCP) • Assay concentrations based on a previous breast cancer case–control study • Only non-cytotoxic concentrations assayed • Both OCP mixtures induce proliferation mediated by oestrogen receptor. • OCP mixture of breast cancer patients exhibits additional androgenic activity.

  20. In vitro evaluation of oestrogenic/androgenic activity of the serum organochlorine pesticide mixtures previously described in a breast cancer case–control study

    Energy Technology Data Exchange (ETDEWEB)

    Rivero, Javier; Luzardo, Octavio P., E-mail: octavio.perez@ulpgc.es; Henríquez-Hernández, Luis A.; Machín, Rubén P.; Pestano, José; Zumbado, Manuel; Boada, Luis D.; Camacho, María; Valerón, Pilar F.

    2015-12-15

    Some organochlorine pesticides (OCs) have been individually linked to breast cancer (BC) because they exert oestrogenic effects on mammary cells. However, humans are environmentally exposed to more or less complex mixtures of these organochlorines, and the biological effects of these mixtures must be elucidated. In this work we evaluated the in vitro effects exerted on human BC cells by the OC mixtures that were most frequently detected in two groups of women who participated in a BC case–control study developed in Spain: healthy women and women diagnosed with BC. The cytotoxicity, oestrogenicity, and androgenicity of the most prevalent OC mixtures found in healthy women (H-mixture) and in BC patients (BC-mixture) were tested at concentrations that resembled those found in the serum of the evaluated women. Our results showed that both OC mixtures presented a similar oestrogenic activity and effect on cell viability, but BC-mixture showed an additional anti-androgenic effect. These results indicate that although the proliferative effect exerted by these mixtures on human breast cells seems to depend mainly on their oestrogenic action, the BC-mixture might additionally induce cell proliferation due to its anti-androgenic activity, therefore increasing the carcinogenic potential of this mixture. The findings of this study demonstrate that subtle variations in the composition of a mixture may induce relevant changes in its biological action. - Highlights: • E-screen and A-screen of two mixtures of organochlorine pesticides (OCP) • Assay concentrations based on a previous breast cancer case–control study • Only non-cytotoxic concentrations assayed • Both OCP mixtures induce proliferation mediated by oestrogen receptor. • OCP mixture of breast cancer patients exhibits additional androgenic activity.

  1. Marine geology

    Digital Repository Service at National Institute of Oceanography (India)

    Rao, V.P.; Shankar, R.

    -bearing and gas hydrates) sediments along the Indian continental margins, by using geophysical methods, is a significant achievement in this decade. Authigenic green clay facies, phosphorites have been studied in detail in order to reconstruct the paleogeography...

  2. Lower Paleozoic deep-water facies of the Medfra area, central Alaska: A section in Geologic studies in Alaska by the U.S. Geological Survey, 1997

    Science.gov (United States)

    Dumoulin, Julie A.; Bradley, Dwight C.; Harris, Anita G.; Repetski, John E.

    1999-01-01

    Deep-water facies, chiefly hemipelagic deposits and turbidites, of Cambrian through Devonian age are widely exposed in the Medfra and Mt. McKinley quadrangles. These strata include the upper part of the Telsitna Formation (Middle-Upper Ordovician) and the Paradise Fork Formation (Lower Silurian-Lower Devonian) in the Nixon Fork terrane, the East Fork Hills Formation (Upper Cambrian-Lower Devonian) in the East Fork subterrane of the Minchumina terrane, and the chert and argillite unit (Ordovician) and the argillite and quartzite unit (Silurian- Devonian? and possibly older) in the Telida subterrane of the Minchumina terrane.In the western part of the study area (Medfra quadrangle), both hemipelagic deposits and turbidites are largely calcareous and were derived from the Nixon Fork carbonate platform. East- ern exposures (Mt. McKinley quadrangle; eastern part of the Telida subterrane) contain much less carbonate; hemipelagic strata are mostly chert, and turbidites contain abundant rounded quartz and lesser plagioclase and potassium feldspar. Deep-water facies in the Medfra quadrangle correlate well with rocks of the Dillinger terrane exposed to the south (McGrath quadrangle), but coeval strata in the Mt. McKinley quadrangle are compositionally similar to rocks to the northeast (Livengood quadrangle). Petrographic data thus suggest that the Telida subterranes presently defined is an artificial construct made up of two distinct sequences of disparate provenance.Restoration of 90 and 150 km of dextral strike-slip on the Iditarod and Farewell faults, respectively, aligns the deep-water strata of the Minchumina and Dillinger terranes in a position east of the Nixon Fork carbonate platform. This restoration supports the interpretation that lower Paleozoic rocks in the Nixon Fork and Dillinger terranes, and in the western part of the Minchumina terrane (East Fork subterrane and western part of the Telida subterrane), formed along a single continental margin. Rocks in the

  3. Kinderhookian (Lower Mississippian) calcareous rocks of the Howard Pass quadrangle, western Brooks Range: A section in Geologic studies in Alaska by the U.S. Geological Survey, 1995

    Science.gov (United States)

    Dumoulin, Julie A.; Harris, Anita G.

    1997-01-01

    Calcareous rocks of Kinderhookian (early Early Mississippian) age are widely distributed across the Howard Pass quadrangle in the western Brooks Range. Most occur in the lower part of the Lisburne Group (herein called the Rough Mountain Creek unit) and the upper part of the Endicott Group (Kayak Shale) in two sequences (Key Creek and Aniuk River) of the Endicott Mountains allochthon. Kinderhookian strata are also found in the Kelly River allochthon (Utukok Formation?) and in sections of uncertain stratigraphic affinity and structural level spatially associated with mafic volcanic rocks.Predominant Kinderhookian lithologies in the Lisburne Group are skeletal supportstone (rich in pelmatozoans, bryozoans, and brachiopods) and lesser spiculite; skeletal supportstone and calcarenite are the chief calcareous rock types in the Kayak Shale. Conodont and brachiopod faunas indicate that all of the Rough Mountain Creek unit and much of the Kayak Shale in the study area are of late Kinderhookian age. Lithologic and paleontologic data suggest that Kinderhookian strata in the Howard Pass quadrangle were deposited largely in inner- and middle-shelf settings with normal marine salinity and locally high energy. Overall, calcareous beds in the Rough Mountain Creek unit accumulated in a wider range of environments, less subject to siliciclastic input, than did calcareous beds in the Kayak, and Kinderhookian beds of both units in the Key Creek sequence formed in less diverse, somewhat shallower environments than correlative rocks in the Aniuk River sequence. Lithofacies patterns and contact relations imply that decreased siliciclastic influx, perhaps accompanied by relative sea-level rise, initiated deposition of the Rough Mountain Creek unit; relative sea-level rise and concurrent circulatory restriction most likely ended its deposition.Kinderhookian calcareous rocks in the Howard Pass quadrangle have several implications for middle Paleozoic paleogeography of the western Brooks

  4. Immunogenicity and safety of tetravalent dengue vaccine in 2-11 year-olds previously vaccinated against yellow fever: randomized, controlled, phase II study in Piura, Peru.

    Science.gov (United States)

    Lanata, Claudio F; Andrade, Teresa; Gil, Ana I; Terrones, Cynthia; Valladolid, Omar; Zambrano, Betzana; Saville, Melanie; Crevat, Denis

    2012-09-07

    In a randomized, placebo-controlled, monocenter, observer blinded study conducted in an area where dengue is endemic, we assessed the safety and immunogenicity of a recombinant, live, attenuated, tetravalent dengue vaccine candidate (CYD-TDV) in 2-11 year-olds with varying levels of pre-existing yellow-fever immunity due to vaccination 1-7 years previously. 199 children received 3 injections of CYD-TDV (months 0, 6 and 12) and 99 received placebo (months 0 and 6) or pneumococcal polysaccharide vaccine (month 12). One month after the third dengue vaccination, serotype specific neutralizing antibody GMTs were in the range of 178-190 (1/dil) (versus 16.7-38.1 in the control group), a 10-20 fold-increase from baseline, and 94% of vaccines were seropositive to all four serotypes (versus 39% in the control group). There were no vaccine-related SAEs. The observed reactogenicity profile was consistent with phase I studies, with severity grade 1-2 injection site pain, headache, malaise and fever most frequently reported and no increase after subsequent vaccinations. Virologically confirmed dengue cases were seen after completion of the 3 doses: 1 in the CYD-TDV group (N=199), and 3 in the control group (N=99). A 3-dose regimen of CYD-TDV had a good safety profile in 2-11 year olds with a history of YF vaccination and elicited robust antibody responses that were balanced against the four serotypes. Copyright © 2012 Elsevier Ltd. All rights reserved.

  5. A real life study of Helicobacter pylori eradication with bismuth quadruple therapy in naïve and previously treated patients

    Directory of Open Access Journals (Sweden)

    Blas José Gómez-Rodríguez

    Full Text Available Objective: To evaluate the efficacy and safety of a quadruple regimen (BMTO of the "3-in-1 capsule" (containing bismuth subcitrate potassium, metronidazole and tetracycline plus omeprazole in naïve and previously treated patients diagnosed with Helicobacter pylori (H. pylori infection in the clinical setting in Seville (Spain. Methods: This is a prospective study carried out on consecutive patients with a confirmed H. pylori infection and upper gastrointestinal symptoms. After providing their informed consent, the patients were treated for ten days with a 3-in-1 capsule containing bismuth subcitrate potassium (140 mg, metronidazole (125 mg and tetracycline (125 mg: Pylera®, three capsules four times daily, plus omeprazole (20 or 40 mg twice daily. Eradication of infection was determined by a negative urea breath test at least 28 days after the end of treatment. Results: A total of 58 consecutive patients were enrolled into this study, two of whom withdrew early due to vomiting on days three and five, respectively. In this cohort, 17 patients (29.3% had a prior history of medication to treat H. pylori. In the intent-to-treat population, eradication was achieved in 97.6% (40/41 and 82.4% (14/17 of cases in patients treated with BMTO as a first-line or rescue therapy, respectively. At least one adverse event was reported by 28 (48% patients, mostly mild effects (86%. Conclusion: A ten day treatment with BMTO is an effective and safe strategy to combat confirmed H. pylori infection in patients.

  6. A phase II study of VP-16-ifosfamide-cisplatin combination chemotherapy plus early concurrent thoracic irradiation for previously untreated limited small cell lung cancer

    Energy Technology Data Exchange (ETDEWEB)

    Woo, In Sook; Park, Young Suk; Kwon, Sung Hee [Hallym Univ., Seoul (Korea, Republic of). Coll. of Medicine] [and others

    2000-12-01

    At present the addition of thoracic irradiation to combination chemotherapy is a standard treatment for limited staged small cell ling cancer. However, there is still controversy about the optimum timing of chest irradiation. We conducted a phase II study of etoposide (VP-16)-ifosfamide-cisplatin (VIP) combination chemotherapy plus early concurrent thoracic irradiation for the patients with previously untreated limited small cell lung cancer in order to assess if the treatment modality could improve the response rate and the toxicity. Forty-four patients with limited small cell lung cancer were treated with etoposide-ifosfamide-cisplatin and concurrent thoracic irradiation. Combination chemotherapy consisted of etoposide 100 mg/m{sup 2} (on day 1-3), ifosfamide 1000 mg/m{sup 2} (on days 1 and 2) and cisplatin 100 mg/m{sup 2} (on day 1). Concurrent thoracic irradiation consisted of a total of 4000 cGy over 4 weeks starting on the first day of the first chemotherapy. All patients who showed a complete response were given prophylactic cranial irradiation for 2.5 weeks. Forty-four of the 49 patients who entered the study from May 1994 to August 1998 were evaluable. The median age was 59 years and 40 patients had a performance status of 0 or 1. The median survival time was 22.5 months. Twenty-eight patients (62%) showed a complete response and 16 (38%) a partial response. Twenty-four patients (54%) developed grade 3 or 4 neutropenia; there was a 9% RTOG score 3 or 4 esophagitis. VIP combination chemotherapy and early concurrent thoracic irradiation for patients with limited stage small cell lung cancer revealed excellent antitumor response with tolerable toxicity. (author)

  7. Studies on environmental geology of the northwest disposal site for low and intermediate level radioactive solid wastes

    International Nuclear Information System (INIS)

    Xu Guoqing; Jin Yuanxin; Wang Ju; Li Sen; Xiao Xiangping

    1998-01-01

    The Northwest Disposal Site is used for disposal of low and intermediate level radioactive solid wastes in China. There are no poor geological phenomena in the site. The site has favorable engineering geological conditions. There is no phreatic water in the Quaternary sediments. The depth of confined water level in the Tertiary sediments is relatively deep. The groundwater recharge, runoff and discharge conditions are ascertained. Actual flow rate, direction, dispersity and dispersion coefficients of groundwater are achieved by the dispersion tests. The coefficient of unsaturated permeability of the rocks and soils of the site are obtained by research of the aerated zone. Rocks and soils of the site have higher exchangeable Ca 2+ . They with effectually adsorb and retard the 63 Ni and 239 Pu. There are many favourable environmental geological conditions at the Northwest Disposal Site. The site will provide effective natural barriers for low and intermediate level radioactive solid wastes

  8. Geologic map of the Great Smoky Mountains National Park region, Tennessee and North Carolina

    Science.gov (United States)

    Southworth, Scott; Schultz, Art; Aleinikoff, John N.; Merschat, Arthur J.

    2012-01-01

    The geology of the Great Smoky Mountains National Park region of Tennessee and North Carolina was studied from 1993 to 2003 as part of a cooperative investigation by the U.S. Geological Survey with the National Park Service (NPS). This work resulted in a 1:100,000-scale geologic map derived from mapping that was conducted at scales of 1:24,000 and 1:62,500. The geologic data are intended to support cooperative investigations with the NPS, the development of a new soil map by the Natural Resources Conservation Service, and the All Taxa Biodiversity Inventory. In response to a request by the NPS, we mapped previously unstudied areas, revised the geology where problems existed, and developed a map database for use in interdisciplinary research, land management, and interpretive programs for park visitors.

  9. Study of geologic-structural situation around Semipalatinsk test site test - holes using space images automated decoding method

    International Nuclear Information System (INIS)

    Gorbunova, Eh.M.; Ivanchenko, G.N.

    2004-01-01

    Performance of underground nuclear explosions (UNE) leads to irreversible changes in geological environment around the boreholes. In natural environment it was detected inhomogeneity of rock massif condition changes, which depended on characteristics of the underground nuclear explosion, anisotropy of medium and presence of faulting. Application of automated selection and statistic analysis of unstretched lineaments in high resolution space images using special software pack LESSA allows specifying the geologic-structural features of Semipalatinsk Test Site (STS), ranging selected fracture zones, outlining and analyzing post-explosion zone surface deformations. (author)

  10. Geologic distributions of US oil and gas

    International Nuclear Information System (INIS)

    1992-01-01

    This publication presents nonproprietary field size distributions that encompass most domestic oil and gas fields at year-end 1989. These data are organized by geologic provinces as defined by the American Association of Petroleum Geologists' Committee on Statistics of Drilling (AAPG/CSD), by regional geographic aggregates of the AAPG/CSD provinces, and Nationally. The report also provides partial volumetric distributions of petroleum liquid and natural gas ultimate recoveries for three macro-geologic variables: principal lithology of the reservoir rock, principal trapping condition and geologic age of the reservoir rock, The former two variables are presented Nationally and by geographic region, in more detail than has heretofore been available. The latter variable is provided Nationally at the same level of detail previously available. Eighteen tables and 66 figures present original data on domestic oil and gas occurrence. Unfortunately, volumetric data inadequacy dictated exclusion of Appalachian region oil and gas fields from the study. All other areas of the United States known to be productive of crude oil or natural gas through year-end 1989, onshore and offshore, were included. It should be noted that none of the results and conclusions would be expected to substantively differ had data for the Appalachian region been available for inclusion in the study

  11. Geology of Europa

    Science.gov (United States)

    Greeley, R.; Chyba, C.; Head, J. W.; McCord, T.; McKinnon, W. B.; Pappalardo, R. T.

    2004-01-01

    Europa is a rocky object of radius 1565 km (slightly smaller than Earth s moon) and has an outer shell of water composition estimated to be of order 100 km thick, the surface of which is frozen. The total volume of water is about 3 x 10(exp 9) cubic kilometers, or twice the amount of water on Earth. Moreover, like its neighbor Io, Europa experiences internal heating generated from tidal flexing during its eccentric orbit around Jupiter. This raises the possibility that some of the water beneath the icy crust is liquid. The proportion of rock to ice, the generation of internal heat, and the possibility of liquid water make Europa unique in the Solar System. In this chapter, we outline the sources of data available for Europa (with a focus on the Galileo mission), review previous and on-going research on its surface geology, discuss the astrobiological potential of Europa, and consider plans for future exploration.

  12. Phase I/II study of gefitinib (Iressa(®)) and vorinostat (IVORI) in previously treated patients with advanced non-small cell lung cancer.

    Science.gov (United States)

    Han, Ji-Youn; Lee, Soo Hyun; Lee, Geon Kook; Yun, Tak; Lee, Young Joo; Hwang, Kum Hui; Kim, Jin Young; Kim, Heung Tae

    2015-03-01

    Vorinostat has been shown to overcome resistance to gefitinib. We performed a phase I/II study combining gefitinib with vorinostat in previously treated non-small cell lung cancer (NSCLC). A 3 + 3 dose-escalation design was used to determine maximum tolerated dose (MTD) and recommended phase II dose (RP2D). Three dose levels were tested: 250 mg/day gefitinib on days 1-28 and 200, 300 or 400 mg/day vorinostat on days 1-7, and 15-21 out of every 28 days. The primary endpoint was median progression-free survival (PFS). Fifty-two patients were enrolled and treated (43 in phase II). The median age was 59 years, 28 patients were male, 44 had adenocarcinoma, 29 had never smoked, and 36 had undergone one prior treatment. Twenty-two patients exhibited sensitive EGFR mutations. Planned dose escalation was completed without reaching the MTD. The RP2D was 250 mg gefitinib and 400 mg vorinostat. In 43 assessable patients in phase II, the median PFS was 3.2 months; the overall survival (OS) was 19.0 months. There were 16 partial responses and six cases of stable disease. In EGFR-mutant NSCLC, response rate was 77 %, median PFS was 9.1 months, and median OS was 24.1 months. The most common adverse events were anorexia and diarrhea. Treatment with 250 mg gefitinib daily with biweekly 400 mg/day vorinostat was feasible and well tolerated. In an unselected patient population, this combination dose did not improve PFS. However, this combination showed a potential for improving efficacy of gefitinib in EGFR-mutant NSCLC (NCT01027676).

  13. Effect of donepezil in patients with Alzheimer's disease previously untreated or treated with memantine or nootropic agents in Germany: an observational study.

    Science.gov (United States)

    Klinger, Tatjana; Ibach, Bernd; Schoenknecht, Peter; Kamleiter, Martin; Silver, Gabrielle; Schroeder, Johannes; Mielke, Ruediger

    2005-05-01

    This open-label, prospective, observational, Post-Marketing Surveillance (PMS) study assessed the efficacy and safety of donepezil in patients who had been switched from therapies currently used in Germany to treat Alzheimer's disease (AD), such as memantine and nootropics, due to insufficient efficacy or poor tolerability. A treatment-naive population was included as a comparator. Patients with AD were treated with donepezil and observed for a period of approximately 3 months. A cognitive assessment was made using the Mini-Mental State Examination (MMSE). Quality of life (QoL) was assessed by the investigators who answered the question 'How did therapy with donepezil influence the QoL of the patient and/or his family over the observation period?' and was graded using three ratings: improved/unchanged/worsened. Adverse events (AEs) were also monitored. A total of 913 patients entered the study (mean +/- SD MMSE score 18.03 +/- 5.34). Efficacy assessments were analyzed for three groups: an overall group of patients who had received any form of prior AD drug therapy (N+ group; n = 709); a subgroup of patients from the N+ group who had received prior memantine therapy only (M+ group; n = 111) and patients who were drug treatment naive (N- group; n = 204). In the evaluable population donepezil improved MMSE scores by 2.21 +/- 3.47 points on average, with similar improvements observed in all three groups. QoL was judged to be improved in at least 70% of patients, again with similar results obtained for all three groups. Donepezil was well tolerated, with 85 of 913 (9.3%) patients reporting AEs. The most common AEs were those typically seen with cholinergic therapies (i.e., diarrhoea, vomiting and nausea). In this observational PMS study, donepezil was shown to be efficacious and well tolerated in patients who were being insufficiently treated with memantine or nootropic therapy. The magnitude of response was similar to that observed in patients who were previously

  14. A new method for studying the transport of gamma photons in various geological materials by combining the SSNTD technique with Monte Carlo simulations

    International Nuclear Information System (INIS)

    Misdaq, M.A.; Merzouki, A.; Bourzik, W.; Sfairi, T.

    2000-01-01

    The gamma dose rate due to the uranium and thorium series as well as the potassium 40 nuclei represents a large fraction of the total dose rate from the natural background. Natural gamma-activities of rock and soil samples collected from volcanic areas have been determined using gamma-ray spectrometry. The corresponding gamma dose rates in air have been measured by means of thermoluminescence (TL) dosimeters. Annual absorbed gamma dose rates have been evaluated in different soil samples belonging to an archaeological site by using experimental and calculational methods. Uranium and thorium contents in different geological samples have been determined by using CR-39 and LR-115 type II solid state nuclear track detectors (SSNTD) and calculating the probabilities for alpha particles emitted by the uranium and thorium series to reach and be registered on the SSNTD films. A new method has been developed based on calculating the self-absorption and transmission coefficients of the gamma photons emitted by the uranium and thorium families as well as the potassium 40 isotope for evaluating the gamma dose rate in the considered geological samples. Transport of gamma-photons across parallelepipedic blocks of the geological materials studied has been investigated. Gamma dose rates have been evaluated in the atmosphere of different geological deposits. (author)

  15. How do geological sampling biases affect studies of morphological evolution in deep time? A case study of pterosaur (Reptilia: Archosauria) disparity.

    Science.gov (United States)

    Butler, Richard J; Brusatte, Stephen L; Andres, Brian; Benson, Roger B J

    2012-01-01

    A fundamental contribution of paleobiology to macroevolutionary theory has been the illumination of deep time patterns of diversification. However, recent work has suggested that taxonomic diversity counts taken from the fossil record may be strongly biased by uneven spatiotemporal sampling. Although morphological diversity (disparity) is also frequently used to examine evolutionary radiations, no empirical work has yet addressed how disparity might be affected by uneven fossil record sampling. Here, we use pterosaurs (Mesozoic flying reptiles) as an exemplar group to address this problem. We calculate multiple disparity metrics based upon a comprehensive anatomical dataset including a novel phylogenetic correction for missing data, statistically compare these metrics to four geological sampling proxies, and use multiple regression modeling to assess the importance of uneven sampling and exceptional fossil deposits (Lagerstätten). We find that range-based disparity metrics are strongly affected by uneven fossil record sampling, and should therefore be interpreted cautiously. The robustness of variance-based metrics to sample size and geological sampling suggests that they can be more confidently interpreted as reflecting true biological signals. In addition, our results highlight the problem of high levels of missing data for disparity analyses, indicating a pressing need for more theoretical and empirical work. © 2011 The Author(s). Evolution © 2011 The Society for the Study of Evolution.

  16. Geologic Map of the Atlin Quadrangle, Southeastern Alaska

    Science.gov (United States)

    Brew, David A.; Himmelberg, Glen R.; Ford, Arthur B.

    2009-01-01

    This map presents the results of U.S. Geological Survey (USGS) geologic bedrock mapping studies in the mostly glacier covered Atlin 1:250,000-scale quadrangle, northern southeastern Alaska. These studies are part of a long-term systematic effort by the USGS to provide bedrock geologic and mineral-resource information for all of southeastern Alaska, covering all of the Tongass National Forest (including Wilderness Areas) and Glacier Bay National Park and Preserve. Some contributions to this effort are those concerned with southwesternmost part of the region, the Craig and Dixon Entrance quadrangles (Brew, 1994; 1996) and with the Wrangell-Petersburg area (Brew, 1997a-m; Brew and Grybeck, 1997; Brew and Koch, 1997). As shown on the index map (fig. 1), the study area is almost entirely in the northern Coast Mountains adjacent to British Columbia, Canada. No previous geologic map has been published for the area, although Brew and Ford (1985) included a small part of it in a preliminary compilation of the adjoining Juneau quadrangle; and Brew and others (1991a) showed the geology at 1:500,000 scale. Areas mapped nearby in British Columbia and the United States are also shown on figure 1. All of the map area is in the Coast Mountains Complex as defined by Brew and others (1995a). A comprehensive bibliography is available for this and adjacent areas (Brew, 1997n).

  17. Tsunami geology in paleoseismology

    Science.gov (United States)

    Yuichi Nishimura,; Jaffe, Bruce E.

    2015-01-01

    The 2004 Indian Ocean and 2011 Tohoku-oki disasters dramatically demonstrated the destructiveness and deadliness of tsunamis. For the assessment of future risk posed by tsunamis it is necessary to understand past tsunami events. Recent work on tsunami deposits has provided new information on paleotsunami events, including their recurrence interval and the size of the tsunamis (e.g. [187–189]). Tsunamis are observed not only on the margin of oceans but also in lakes. The majority of tsunamis are generated by earthquakes, but other events that displace water such as landslides and volcanic eruptions can also generate tsunamis. These non-earthquake tsunamis occur less frequently than earthquake tsunamis; it is, therefore, very important to find and study geologic evidence for past eruption and submarine landslide triggered tsunami events, as their rare occurrence may lead to risks being underestimated. Geologic investigations of tsunamis have historically relied on earthquake geology. Geophysicists estimate the parameters of vertical coseismic displacement that tsunami modelers use as a tsunami's initial condition. The modelers then let the simulated tsunami run ashore. This approach suffers from the relationship between the earthquake and seafloor displacement, the pertinent parameter in tsunami generation, being equivocal. In recent years, geologic investigations of tsunamis have added sedimentology and micropaleontology, which focus on identifying and interpreting depositional and erosional features of tsunamis. For example, coastal sediment may contain deposits that provide important information on past tsunami events [190, 191]. In some cases, a tsunami is recorded by a single sand layer. Elsewhere, tsunami deposits can consist of complex layers of mud, sand, and boulders, containing abundant stratigraphic evidence for sediment reworking and redeposition. These onshore sediments are geologic evidence for tsunamis and are called ‘tsunami deposits’ (Figs. 26

  18. Geological Services Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Researchers use computed tomography (CT) scanners at NETL’s Geological Services Laboratory in Morgantown, WV, to peer into geologic core samples to determine how...

  19. Geophysics & Geology Inspected.

    Science.gov (United States)

    Neale, E. R. W.

    1981-01-01

    Summarizes findings of a recently published report of the Canadian Geoscience Council, which includes the following topics regarding college geology: facilities; teaching; undergraduate enrollments; postgraduate enrollments; geologic research; and integration of Canadian geoscience with other countries. (CS)

  20. Geology of Uruguay review

    International Nuclear Information System (INIS)

    Gomez Rifas, C.

    2011-01-01

    This work is about the Uruguay geology review.This country has been a devoted to breeding cattle and agriculture.The evolution of geological knowledge begun with Dr. Karl Walther who published 53 papers between 1909 and 1948.

  1. Technical summary of geological, hydrological, and engineering studies at the Slick Rock Uranium Mill Tailings sites, Slick Rock, Colorado

    International Nuclear Information System (INIS)

    1990-12-01

    The purpose of this document is to provide the Colorado Department of Health (CDH) with a summary of the technical aspects of the proposed remedial action for the Slick Rock tailings near Slick Rock, Colorado. The technical issues summarized in this document are the geology and groundwater at the Burro Canyon disposal site and preliminary engineering considerations for the disposal cell

  2. Caprock and overburden processes in geological CO2 storage: An experimental study on sealing efficiency and mineral alterations

    NARCIS (Netherlands)

    Wollenweber, J.; Alles, S.a.; Kronimus, A.; Busch, A.; Stanjek, H.; Krooss, B.M.

    2009-01-01

    A comprehensive set of experimental and analytical methods has been used to characterise the sealing and fluid -transport properties of fine-grained (pelitic) sedimentary rocks under the pressure and temperature conditions of geological CO2 storage. The flow experiments were carried out on

  3. Regolith-geology mapping with support vector machine: A case study over weathered Ni-bearing peridotites, New Caledonia

    Science.gov (United States)

    De Boissieu, Florian; Sevin, Brice; Cudahy, Thomas; Mangeas, Morgan; Chevrel, Stéphane; Ong, Cindy; Rodger, Andrew; Maurizot, Pierre; Laukamp, Carsten; Lau, Ian; Touraivane, Touraivane; Cluzel, Dominique; Despinoy, Marc

    2018-02-01

    Accurate maps of Earth's geology, especially its regolith, are required for managing the sustainable exploration and development of mineral resources. This paper shows how airborne imaging hyperspectral data collected over weathered peridotite rocks in vegetated, mountainous terrane in New Caledonia were processed using a combination of methods to generate a regolith-geology map that could be used for more efficiently targeting Ni exploration. The image processing combined two usual methods, which are spectral feature extraction and support vector machine (SVM). This rationale being the spectral features extraction can rapidly reduce data complexity by both targeting only the diagnostic mineral absorptions and masking those pixels complicated by vegetation, cloud and deep shade. SVM is a supervised classification method able to generate an optimal non-linear classifier with these features that generalises well even with limited training data. Key minerals targeted are serpentine, which is considered as an indicator for hydrolysed peridotitic rock, and iron oxy-hydroxides (hematite and goethite), which are considered as diagnostic of laterite development. The final classified regolith map was assessed against interpreted regolith field sites, which yielded approximately 70% similarity for all unit types, as well as against a regolith-geology map interpreted using traditional datasets (not hyperspectral imagery). Importantly, the hyperspectral derived mineral map provided much greater detail enabling a more precise understanding of the regolith-geological architecture where there are exposed soils and rocks.

  4. Study on the Seepage and Stability of Carbon Dioxide Geological Storage in Scrap Metal Mine: A Finite Difference Analysis

    Directory of Open Access Journals (Sweden)

    Qingwen Li

    2015-01-01

    Full Text Available The carbon dioxide geological storage is one of the most effective ways to slow down the earth's climate warming. The ideal location for storage is in the deep scrap mines. Because of the characteristics of the deep underground condition, the long-term mechanical stability must have close relationship with the geostress fields and permeability, whose development can determine and reflect the mechanical behaviors of carbon dioxide geological storage. The permeability of host rock is affected by existing joints and discontinuity surfaces. Furthermore, as the liquid carbon dioxide is injected into the geological storage, the injection pressure and buoyancy force will change the state of geostress obviously. In this paper, based on mechanical properties of the host rock (granite, coupled brittle shear constitutive model was adopted and the analysis module was implemented in software FLAC3D. Then, with the in situ survey of joints in the host rock and the monitoring of in situ geostress, the permeability characteristics and geostress inverse analysis were input in FLAC3D. At last, fluid-solid coupled model was used to analyze the seepage characteristics of each phase after the injection and long-term storage of liquid carbon dioxide. Therefore, the systematic analysis of the storage stability of carbon dioxide geological could be carried out.

  5. Phase I study of cisplatin, hyperthermia, and lapatinib in patients with recurrent carcinoma of the uterine cervix in a previously irradiated area

    NARCIS (Netherlands)

    E.V. Meerten (Esther Van); M. Franckena (Martine); E.A.C. Wiemer (Erik); L.V. Doorn (Lena Van); J. Kraan (Jaco); A.M. Westermann (Anneke); S. Sleijfer (Stefan)

    2015-01-01

    textabstractBackground. Patients with recurrent cervical cancer in a previously irradiated area might benefit from cisplatin combined with hyperthermia. Lapatinib inhibits the intracellular tyrosine kinase domain of the epidermal growth factor receptor (EGFR) and HER2. Overexpression of EGFR and

  6. Phase I study of cisplatin, hyperthermia, and lapatinib in patients with recurrent carcinoma of the uterine cervix in a previously irradiated area

    NARCIS (Netherlands)

    van Meerten, Esther; Franckena, Martine; Wiemer, Erik; van Doorn, Lena; Kraan, Jaco; Westermann, Anneke; Sleijfer, Stefan

    2015-01-01

    Patients with recurrent cervical cancer in a previously irradiated area might benefit from cisplatin combined with hyperthermia. Lapatinib inhibits the intracellular tyrosine kinase domain of the epidermal growth factor receptor (EGFR) and HER2. Overexpression of EGFR and HER2 is frequently seen in

  7. A Knowledge-Driven Geospatially Enabled Framework for Geological Big Data

    Directory of Open Access Journals (Sweden)

    Liang Wu

    2017-06-01

    Full Text Available Geologic survey procedures accumulate large volumes of structured and unstructured data. Fully exploiting the knowledge and information that are included in geological big data and improving the accessibility of large volumes of data are important endeavors. In this paper, which is based on the architecture of the geological survey information cloud-computing platform (GSICCP and big-data-related technologies, we split geologic unstructured data into fragments and extract multi-dimensional features via geological domain ontology. These fragments are reorganized into a NoSQL (Not Only SQL database, and then associations between the fragments are added. A specific class of geological questions was analyzed and transformed into workflow tasks according to the predefined rules and associations between fragments to identify spatial information and unstructured content. We establish a knowledge-driven geologic survey information smart-service platform (GSISSP based on previous work, and we detail a study case for our research. The study case shows that all the content that has known relationships or semantic associations can be mined with the assistance of multiple ontologies, thereby improving the accuracy and comprehensiveness of geological information discovery.

  8. Geologic Map and Map Database of Eastern Sonoma and Western Napa Counties, California

    Science.gov (United States)

    Graymer, R.W.; Brabb, E.E.; Jones, D.L.; Barnes, J.; Nicholson, R.S.; Stamski, R.E.

    2007-01-01

    Introduction This report contains a new 1:100,000-scale geologic map, derived from a set of geologic map databases (Arc-Info coverages) containing information at 1:62,500-scale resolution, and a new description of the geologic map units and structural relations in the map area. Prepared as part of the San Francisco Bay Region Mapping Project, the study area includes the north-central part of the San Francisco Bay region, and forms the final piece of the effort to generate new, digital geologic maps and map databases for an area which includes Alameda, Contra Costa, Marin, Napa, San Francisco, San Mateo, Santa Clara, Santa Cruz, Solano, and Sonoma Counties. Geologic mapping in Lake County in the north-central part of the map extent was not within the scope of the Project. The map and map database integrates both previously published reports and new geologic mapping and field checking by the authors (see Sources of Data index map on the map sheet or the Arc-Info coverage eswn-so and the textfile eswn-so.txt). This report contains new ideas about the geologic structures in the map area, including the active San Andreas Fault system, as well as the geologic units and their relations. Together, the map (or map database) and the unit descriptions in this report describe the composition, distribution, and orientation of geologic materials and structures within the study area at regional scale. Regional geologic information is important for analysis of earthquake shaking, liquifaction susceptibility, landslide susceptibility, engineering materials properties, mineral resources and hazards, as well as groundwater resources and hazards. These data also assist in answering questions about the geologic history and development of the California Coast Ranges.

  9. Clinical evaluation of recombinant factor VIII preparation (Kogenate) in previously treated patients with hemophilia A: descriptive meta-analysis of post-marketing study data.

    Science.gov (United States)

    Yoshioka, A; Fukutake, K; Takamatsu, J; Shirahata, A

    2006-08-01

    The safety and efficacy of Kogenate, a recombinant factor VIII (rFVIII) preparation for the treatment of bleeding episodes, were studied in a 123-patient meta-analysis population of previously treated patients (PTPs), including 15 enrolled in the registration Phase III trial (PTP-I group), 93 from the post-marketing special investigation (PTP-II group), and 15 from short-term special investigations in surgery or tooth extraction (SI group). These patients (82 severe, 31 moderate, 9 mild, and 1 unknown), aged 11 months to 72 years, were enrolled in 28 centers in Japan. Blood samples taken at the baseline and at 3, 6, 9, 12, 18, and 24 months after the introduction of Kogenate were evaluated for FVIII inhibitor antibodies, antibodies formed against trace proteins derived from the rFVIII production process, and for general changes in laboratory test results. Mean exposure to Kogenate was 1103 days in PTP-I, 86 days in PTP-II, 27 days in patients in surgery, and 2 days in patients with tooth extraction. Assessment of FVIII inhibitor activity was conducted in 115 of the 123 patients by means of the Bethesda assay. Twelve patients were found to have a low titer of FVIII inhibitor (0.5-3.0 BU/mL) prior to any administration of Kogenate, and 103 were inhibitor-negative at the baseline. Among this latter group, 3 patients (2.9%) tested inhibitor-positive, with titers ranging from 1.2 to 2.1 BU/mL, with 4 patients below 1.0 BU/mL. One patient in the 11 PTPs investigated (PTP-I) developed antibodies against baby hamster kidney protein and mouse immunoglobulin G, but these findings were transient and asymptomatic. Hemostasis was achieved (markedly effective or effective) in 3666 of the 3855 bleeding episodes (95.1%) observed in 108 patients. Only 1 infusion was necessary in 3790 (98.3%) of these episodes. These data indicate that Kogenate is safe and very effective for the treatment of bleeding in PTPs with hemophilia A.

  10. Bedrock geologic map of Vermont

    Science.gov (United States)

    Ratcliffe, Nicholas M.; Stanley, Rolfe S.; Gale, Marjorie H.; Thompson, Peter J.; Walsh, Gregory J.; With contributions by Hatch, Norman L.; Rankin, Douglas W.; Doolan, Barry L.; Kim, Jonathan; Mehrtens, Charlotte J.; Aleinikoff, John N.; McHone, J. Gregory; Cartography by Masonic, Linda M.

    2011-01-01

    The Bedrock Geologic Map of Vermont is the result of a cooperative agreement between the U.S. Geological Survey (USGS) and the State of Vermont. The State's complex geology spans 1.4 billion years of Earth's history. The new map comes 50 years after the most recent map of the State by Charles G. Doll and others in 1961 and a full 150 years since the publication of the first geologic map of Vermont by Edward Hitchcock and others in 1861. At a scale of 1:100,000, the map shows an uncommon level of detail for State geologic maps. Mapped rock units are primarily based on lithology, or rock type, to facilitate derivative studies in multiple disciplines. The 1961 map was compiled from 1:62,500-scale or smaller maps. The current map was created to integrate more detailed (1:12,000- to 1:24,000-scale) modern and older (1:62,500-scale) mapping with the theory of plate tectonics to provide a framework for geologic, tectonic, economic, hydrogeologic, and environmental characterization of the bedrock of Vermont. The printed map consists of three oversize sheets (52 x 76 inches). Sheets 1 and 2 show the southern and northern halves of Vermont, respectively, and can be trimmed and joined so that the entire State can be displayed as a single entity. These sheets also include 10 cross sections and a geologic structure map. Sheet 3 on the front consists of descriptions of 486 map units, a correlation of map units, and references cited. Sheet 3 on the back features a list of the 195 sources of geologic map data keyed to an index map of 7.5-minute quadrangles in Vermont, as well as a table identifying ages of rocks dated by uranium-lead zircon geochronology.

  11. Effects of epilepsy and selected antiepileptic drugs on risk of myocardial infarction, stroke, and death in patients with or without previous stroke: a nationwide cohort study

    DEFF Research Database (Denmark)

    Olesen, J. B.; Abildstrom, S. Z.; Erdal, Jesper

    2011-01-01

    Purpose Patients with epilepsy have increased morbidity and mortality. We evaluated the risk of myocardial infarction (MI), stroke, and death associated with epilepsy and examined if this risk was modified by treatment with antiepileptic drugs (AEDs). Methods A cohort consisting of the Danish...... population was followed from January 1997 to December 2006. The risk of MI, stroke, cardiovascular death, and all-cause death associated with epilepsy was estimated by multivariable Cox proportional hazard models stratified for occurrence of previous stroke. AED use was determined at baseline, and risks...... associated with exposure to individual AEDs were examined in patients with epilepsy. Results In patients without previous stroke, AED-treated epilepsy was associated with an increased risk of MI (hazard ratio [HR], 1.09; 95%CI, 1.00-1.19), stroke (HR, 2.22; 95%CI, 2.09-2.36), cardiovascular death (HR, 1...

  12. A pilot study of the combination of cyclosporin A and interferon alfacon-1 for the treatment of hepatitis C in previous nonresponder patients.

    Science.gov (United States)

    Cotler, Scott J; Morrissey, Mary J; Wiley, Thelma E; Layden, Thomas J; Jensen, Donald M

    2003-04-01

    To evaluate the safety and efficacy of the combination of interferon and cyclosporine for the treatment of hepatitis C in previous nonresponder patients. Preliminary data indicated that adding the immunosuppressive agent cyclosporin A to interferon might improve response rates in patients with hepatitis C. Ten previous virologic nonresponders with genotype 1 infection were included. Treatment consisted of interferon alfacon-1, 15 microg/d, and cyclosporine, 100 mg twice daily, for 4 weeks. The dose of interferon alfacon-1 was then decreased to 15 microg three times weekly, and cyclosporine was reduced to 50 mg twice daily. Therapy was continued for 48 weeks unless viremia persisted at week 24. Three of 10 subjects had an on-treatment virologic response, although one had a breakthrough with recurrent viremia during treatment and two relapsed after therapy was completed. On treatment responders had significantly higher trough cyclosporine levels at week 4 compared with nonresponders (P = 0.025). Serum creatinine levels remained stable, and no patient developed diabetes. Triglyceride levels increased during treatment. Cyclosporine was dose reduced in two patients for hypertension. Selected patients with hepatitis C tolerated therapy, including cyclosporine without severe or irreversible toxicity. Despite an association between higher cyclosporine levels and on-treatment response, the combination of cyclosporine and interferon was ineffective in producing a sustained response in previous nonresponder patients.

  13. Health benefits of geologic materials and geologic processes

    Science.gov (United States)

    Finkelman, R.B.

    2006-01-01

    The reemerging field of Medical Geology is concerned with the impacts of geologic materials and geologic processes on animal and human health. Most medical geology research has been focused on health problems caused by excess or deficiency of trace elements, exposure to ambient dust, and on other geologically related health problems or health problems for which geoscience tools, techniques, or databases could be applied. Little, if any, attention has been focused on the beneficial health effects of rocks, minerals, and geologic processes. These beneficial effects may have been recognized as long as two million years ago and include emotional, mental, and physical health benefits. Some of the earliest known medicines were derived from rocks and minerals. For thousands of years various clays have been used as an antidote for poisons. "Terra sigillata," still in use today, may have been the first patented medicine. Many trace elements, rocks, and minerals are used today in a wide variety of pharmaceuticals and health care products. There is also a segment of society that believes in the curative and preventative properties of crystals (talismans and amulets). Metals and trace elements are being used in some of today's most sophisticated medical applications. Other recent examples of beneficial effects of geologic materials and processes include epidemiological studies in Japan that have identified a wide range of health problems (such as muscle and joint pain, hemorrhoids, burns, gout, etc.) that may be treated by one or more of nine chemically distinct types of hot springs, and a study in China indicating that residential coal combustion may be mobilizing sufficient iodine to prevent iodine deficiency disease. ?? 2006 MDPI. All rights reserved.

  14. Health Benefits of Geologic Materials and Geologic Processes

    Directory of Open Access Journals (Sweden)

    Robert B. Finkelman

    2006-12-01

    Full Text Available The reemerging field of Medical Geology is concerned with the impacts of geologic materials and geologic processes on animal and human health. Most medical geology research has been focused on health problems caused by excess or deficiency of trace elements, exposure to ambient dust, and on other geologically related health problems or health problems for which geoscience tools, techniques, or databases could be applied. Little, if any, attention has been focused on the beneficial health effects of rocks, minerals, and geologic processes. These beneficial effects may have been recognized as long as two million years ago and include emotional, mental, and physical health benefits. Some of the earliest known medicines were derived from rocks and minerals. For thousands of years various clays have been used as an antidote for poisons. “Terra sigillata,” still in use today, may have been the first patented medicine. Many trace elements, rocks, and minerals are used today in a wide variety of pharmaceuticals and health care products. There is also a segment of society that believes in the curative and preventative properties of crystals (talismans and amulets. Metals and trace elements are being used in some of today’s most sophisticated medical applications. Other recent examples of beneficial effects of geologic materials and processes include epidemiological studies in Japan that have identified a wide range of health problems (such as muscle and joint pain, hemorrhoids, burns, gout, etc. that may be treated by one or more of nine chemically distinct types of hot springs, and a study in China indicating that residential coal combustion may be mobilizing sufficient iodine to prevent iodine deficiency disease.

  15. A Data mining and Meta-Analysis of Geodiversity and Geological Preservation Studies: Pedodiversity, the Other Side of the Coin

    Science.gov (United States)

    Ibáñez, Juanjo; Brevik, Eric C.; Cerdà, Artemi

    2017-04-01

    Land degradation processes are complex and diverse (Yan and Cai, 2015; Álvarez-Martínez et al., 2016; Zhang et al., 2016). To understand the processes of degradation there is the need to understand a wide range of factors, including the sociological, biological, hydrological and geological components of the ecosystems (de Araujo et al., 2015; Li et al., 2016; Muñoz Rojas et al., 2016; Rodrigo Comino et al., 2016). Although the most widely accepted definitions of geodiversity include geology, landforms and soils, in practice published studies on the preservation of geodiversity typically ignore the soil resource and pay more attention to other items, while many others do not include soils in such definitions. Soils are a key component of the Earth system as they regulate the hydrological, erosional, biological and geochemical Earth cycles (Keesstra et al., 2012; Brevik et al., 2015), offer resources, goods and services to human societies (Mol and Keesstra, 2012), and are a key issue in the United Nations goals to achieve sustainability (Keesstra et al., 2016). The preservation of pedodiversity is practically ignored by governments. The same can be said in the acceptance of geoparks by UNESCO, when soils are ignored. A few researchers have paid attention to geodiversity (Ibáñez et al., 2016; Stavi et al., 2016). In this study a data mining and metanalysis of this topic has been carried out using four different sources; Google, Google Scholar, Scopus, and the contents of Geoheritage journal. The results obtained show the same trends in all four studied sources. Soil resources are neglected in geodiversity studies as well as in the preservation of geological heritage against the scientific rationality inherent in the definition of geodiversity. Furthermore, pedodiversity studies have been carried out by a small set of interested pedologists following the same conceptual frames and mathematical tools reaching interesting universal patterns and a common language

  16. Geochemical studies for geologic disposal of high-level radioactive waste. Research activities in Department of Environmental Safety Research, Japan Atomic Energy Research Institute

    International Nuclear Information System (INIS)

    Nakayama, Shinichi; Sato, Tsutomu; Nagano, Tetsushi; Yanase, Nobuyuki; Yamaguchi, Tetsuji; Isobe, Hiroshi; Ohnuki, Toshihiko; Sekine, Keiichi

    1995-07-01

    The Environmental Geochemistry Laboratory of the Department of Environmental Safety Research of JAERI (EGL/JAERI) is responsible for performing fundamental research to support the geologic disposal of high-level radioactive waste and the performance assessment of the disposal concept. This research includes basic laboratory experiments as well as field studies of natural analogs to understand the geochemical behavior of radionuclides, i.e., the interactions between radionuclides, groundwater and geological materials. This report summarizes background, objectives and recent results of the scientific investigations and emphasizes the significance of these studies in terms of both fundamental research on geochemistry and applied research for performance assessment of the waste disposal concept. The importance of performing fundamental research to radioactive waste disposal is stressed in this report. The report is aimed at both the radioactive waste disposal scientific community and the interdisciplinary sciences that interact with this community. (author)

  17. The geological attitude

    International Nuclear Information System (INIS)

    Fuller, J.G.C.M.

    1992-01-01

    This paper discusses geological activity which takes place mainly in response to industrial and social pressures. Past geological reaction to these pressures profoundly altered popular conceptions of time, the Church, man, and the balance of nature. The present-day circumstances of geology are not essentially different from those of the past. Petroleum geology in North American illustrates the role of technology in determining the style and scope of geological work. Peaks of activity cluster obviously on the introduction from time to time of new instrumental capabilities (geophysical apparatus, for example), although not infrequently such activity is testing concepts or relationships perceived long before. Organic metamorphism and continental drift provide two examples. The petroleum industry now faces the dilemma of satisfying predicted demands for fuel, without doing irreparable injury to its environment of operation. Awareness of man's place in nature, which is a fundamental perception of geology, governs the geological attitude

  18. Geological Geophysical and structural studies in Mina Ratones (Pluton de Albala); Estudios geologico-estructurales y geofisicos en Mina Ratones (Pluton de Albala)

    Energy Technology Data Exchange (ETDEWEB)

    Perez-Estaun, A.; Carbonell, R.; Marti, D.; Flecha, I. [Instituto de Ciencias de la Tierra Jaume Almera. Barcelona (Spain); Escuder Viruete, J. [Universidad complutense de Madrid. Madrid (Spain)

    2002-07-01

    Mina Ratones environmental restoration project included petrological, structural,geophysical, hydrogeological and hydrogeochemical studies. The main objective of the geologic-structural and geophysical studies was the Albala granite structural characterization around the Mina Ratones uranium mine. The location of facies, fault zones (faults and dykes) as well as the distribution of some physical properties inside the rock massif was obtained for a granitic black of 900, 500, and 500 m. The geologic-structural and geophysical techniques applied to Mina Ratones provided a multidisciplinary approach for high resolution characterization of rock massif, and the structures potentially containing fluids,able to be applied to the hydrogeological modelling to a particular area. Geological studies included a detailed structural mapping of the area surrounding the mine (1:5,000 scale), the geometric, kinematics, and dynamics analysis of fractures of all scales, the petrology and geochemistry of fault rocks and altered areas surrounding fractures, and the microstructural studies of samples from surface and core lags. The construction of geostatistical models in two and three dimensions had helped to characterize the Mina Ratones rock massif showing the spatial distribution of fault zones, fracture intensity, granite composition heterogeneities, fluid-rock interaction zones, and physical properties. (Author)

  19. Automated pattern recognition to support geological mapping and exploration target generation: a case study from southern Namibia

    CSIR Research Space (South Africa)

    Eberle, D

    2015-06-01

    Full Text Available 31573236; +264 81 7781480 fax: +49 341 235 1939 Email: d.eberle@rohstoffe.org Keywords: Cluster analysis; discriminant analysis; lineament detection; mapping; southern Namibia, Namaqua Metamorphic Belt. Manuscript submitted for publication... gamma-ray data were integrated with selected Landsat band data using unsupervised fuzzy partitioning clustering. The outcome of this unsupervised clustering is a classified (zonal) map which in terms of spatial resolution is superior to any geological...

  20. A preliminary study on the suitability of host rocks for deep geological disposal of high level radioactive waste in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chun Soo; Bae, Dae Seok; Kim, Kyung Su; Park, Byung Yun; Koh, Young Kown

    2000-02-01

    It is expected that the key issues are listed as the disposal concept, reference disposal system and other relevant technical development for the deep geological disposal of HLW in each country. First above all, however, the preferred host rocks should be suggested prior execution of these activities. And, it is desirable to be reviewed and proposed some host rocks representative its country. For the reviewing of host rocks in Korean peninsula, several issues were considered such as the long-term geological stability, fracture system, surface and groundwater system and geochemical characteristics in peninsula. The three rock types such as plutonic rocks, crystalline gneisses and massive volcanic rocks were suggested as the preferred host rocks for the R and D of HLW disposal based on the upper stated information. In the following stages, it is suggested that these preferred host rocks would be made an object of all relevant R and D activities for HLW disposal. And, many references for these geologic medium should be characterized and constructed various technical development for the Korean reference disposal system.

  1. REVITALIZATION OF THE GEOLOGICAL SITES IN THE RURAL AREAS - CASE STUDY OF THE MIECHÓW UPLAND

    Directory of Open Access Journals (Sweden)

    Małgorzata Gonera

    2017-08-01

    Full Text Available The Miechów Upland is one of the meaningful areas for study the Miocene geology. Middle Miocene (Karpatian to Early Sarmatian sediments have been recognised there. The deposits are highly variegated in regard of lithology. Brackish and fresh-water Karpatian sediments are followed by different rocks of broad marine transgression during Moravian, ended by the early Sarmatian ones. Depending on the prominent paleo relief of the Cretaceous basement, a varieties of sediments have been deposited during this time. Marly claystones, silts, sands with mudstone intercalations and detrital limestones (Rhodolith bioherms are the most common. Also the Middle Badenian sulphate evaporates are in the Miechów Upland. State of the Miocene stratotype outcrops had been checked in this area. The access to most of them is impossible cause soil and vegetation coverage within the abandoned opencasts. The only exception is the small, still working silt-pit of the local brick-yard. The solution is effective to both animate the local economy and warrant the access to stratotype section. Due to fertile Pleistocene loess soils the region is extensively use by agriculture, but touched by relevant economic and social problems. The arriving to small-scale opencast mining, accompanied with innovative manufacturing of the resources (silts, clays, sands and carbonates is proposed. Modern mining elaborates a way of working in high level of accordance with the ecological engineering principles and Corporate Social Responsibility (CSR standards so shall not generate nasty threats to the state of soils and agricultural character of the region. A development of unique, regional products on the base of local resources (e.g. unique, regional decorative stones or pottery is worth to be consider by the LEADER program activities. The initiation of innovative mining enterprises and handcraft seems to be a good strategy to improve local economy and promising solution to highlight the image

  2. Effects of local geology on ground motion in the San Francisco Bay region, California—A continued study

    Science.gov (United States)

    Gibbs, James F.; Borcherdt, Roger D.

    1974-01-01

    Measurements of ground motion generated by nuclear explosions in Nevada have been completed for 99 locations in the San Francisco Bay region, California. The seismograms, Fourier amplitude spectra, spectral amplification curves for the signal, and the Fourier amplitude spectra of the seismic noise are presented for 60 locations. Analog amplifications, based on the maximum signal amplitude, are computed for an additional 39 locations. The recordings of the nuclear explosions show marked amplitude variations which are consistently related to the local geologic conditions of the recording site. The average spectral amplifications observed for vertical and horizontal ground motions are, respectively: (1, 1) for granite, (1.5, 1.6) for the Franciscan Formation, (2.3, 2.3), for other pre-Tertiary and Tertiary rocks, (3.0, 2.7) for the Santa Clara Formation, (3.3, 4.4) for older bay sediments, and (3.7, 11.3) for younger bay mud. Spectral amplification curves define predominant ground frequencies for younger bay mud sites and for some older bay sediment sites. The predominant frequencies for most sites were not clearly defined by the amplitude spectra computed from the seismic background noise. The intensities ascribed to various sites in the San Francisco Bay region for the California earthquake of April 18, 1906, are strongly dependent on distance from the zone of surface faulting and the geological character of the ground. Considering only those sites (approximately one square city block in size) for which there is good evidence for the degree of ascribed intensity, the intensities for 917 sites on Franciscan rocks generally decrease with the logarithm of distance as Intensity = 2.69 - 1.90 log (Distance Km). For sites on other geologic units, intensity increments, derived from this empirical rela.tion, correlate strongly with the Average Horizontal Spectral Amplifications (MISA) according to the empirical relation Intensity Increment= 0.27 + 2.70 log(AHSA). Average

  3. Proof study on elucidation of transfer and diffusion mechanism of fluid ranging from adjacent to wide area of geological disposal facility

    International Nuclear Information System (INIS)

    Ishii, Takemasa; Marui, Atsunao; Takahashi, Manabu; Tsukamoto, Hitoshi

    1999-01-01

    Aim of this study are to elucidate transfer and diffusion mechanism of fluid under an environment of deep geological environment by each two geological media such as fractured and porous media, to establish a precise evaluation method on hydrogeological features, to develop a new researching method on transfer and diffusion mechanism of fluid at field, and to conduct model construction and effect evaluation of fluid at deep underground based on measuring values. As a result, on cracking medium, it was found that a value relating to storage rate could be evaluated simultaneously, that both water permeability coefficient and storage rate decreased as sealing pressure of specimen increased, and that change of hydrologic features in specimen could be evaluated more accurately. And, on porous medium, it was conducted to compare mutually two water permeability coefficients obtained by using three kinds of sedimentation rock with different interstitial ratio and two testing methods of transient pulse method and changing water level method. (G.K.)

  4. Geology and geohydrology of the Palo Duro Basin, Texas Panhandle. Report on the progress of nuclear waste isolation feasibility studies, 1978

    International Nuclear Information System (INIS)

    Dutton, S.P.; Finley, R.J.; Galloway, W.E.; Gustavson, T.C.; Handford, C.R.; Presley, M.W.

    1979-01-01

    Early in 1977 the Bureau of Economic Geology was invited to assemble and evaluate geologic data on several salt-bearing basins within the State of Texas as a contribution to the national nuclear repository program. In response to this request, the Bureau, acting as a technical research unit of the University of Texas at Austin and the State of Texas, initiated a long-term program to assemble and interpret all geologic and hydrologic information necessary for delineation, description, and evaluation of salt-bearing strata in the Panhandle area. The technical program can be subdivided into three broad research tasks, which are addressed by a basin analysis group, a surface studies group, and a basin geohydrology group. The basin analysis group has assembled the regional stratigraphic and structural framework of the total basin fill, initiated evaluation of natural resources, and selected stratigraphic core sites for sampling the salt and associated beds. Two drilling sites have provided nearly 8000 feet (2400 m) of core material for analysis and testing of the various lithologies overlying and interbedded with salt units. Concurrently, the surface studies group has collected ground and remotely-sensed data to describe surficial processes, including carbonate and evaporate solution, geomorphic evolution, and fracture system development. The newly formed basin geohydrology group will evaluate both shallow and deep circulation of fluids within the basins. This paper, a summary report of progress, reviews principal conclusions and illustrates the methodologies used and the types of data and displays generated

  5. Technical support for GEIS: radioactive waste isolation in geologic formations. Volume 16. Repository preconceptual design studies: BPNL waste forms in salt

    International Nuclear Information System (INIS)

    1978-04-01

    This volume, Volume 16, ''Repository Preconceptual Design Studies: BPNL Waste Forms in Salt,'' is one of a 23 volume series, ''Technical Support for GEIS: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-36, which supplements the ''Contribution to Draft Generic Environmental Impact Statement on Commercial Waste Management: Radioactive Waste Isolation in Geologic Formations,'' Y/OWI/TM-44. The series provide a more complete technical basis for the preconceptual designs, resource requirements, and environmental source terms associated with isolating commercial LWR wastes in underground repositories in salt, granite, shale and basalt. Wastes are considered from three fuel cycles: uranium and plutonium recycling, no recycling of spent fuel and uranium-only recycling. This document describes a preconceptual design for a nuclear waste storage facility in salt. The waste forms assumed to arrive at the repository were supplied by Battelle Pacific Northwest Laboratories (BPNL). The facility design consists of several chambers excavated deep within a geologic formation together with access shafts and supportive surface structures. The facility design provides for: receiving and unloading waste containers; lowering them down shafts to the mine level; transporting them to the proper storage area and emplacing them in mined storage rooms. Drawings of the facility design are contained in TM-36/17, ''Drawings for Repository Preconceptual Design Studies: BPNL Waste Forms in Salt.''

  6. Case studies: Experience in Canada [Factors affecting public and political acceptance for the implementation of geological disposal

    International Nuclear Information System (INIS)

    2007-01-01

    to involve specialists and citizens in the collaborative development of a management approach. A National Dialogue on Citizen Values was convened to identify the overarching requirements that the public felt should be reflected in a management approach. The NWMO completed its study and submitted its recommendations to the Minister of Natural Resources Canada on November 3, 2005. Continuous monitoring is proposed, as is the potential for retrievability of the spent fuel. An underground characterization facility constructed at the selected central site will support demonstration and confirmation of site suitability. A deep geological repository was selected as the most appropriate which meets the NWMO's stated overriding objectives of safety and security for the long term. Key features include continuous monitoring to support data collection and confirmation of the safety performance of the repository, and the potential for retrievability for an extended period of time. The NFWA sets out requirements for the establishment of trust funds by the waste owners (three nuclear corporations and AECL) to finance the long-term management of spent fuel. The NWMO sough to develop a socially acceptable management approach based on a process of collaborative development with citizens and specialists, who provided technical information, and citizens who established the social and ethical platform. The NWMO study has begun a process of dialogue and engagement with specialists and citizens that will continue through different phases of implementation. Participants emphasized that the manner in which any approach is implemented will be as important as the choice of technical method. Accordingly, in setting out a proposed implementation plan, NWMO has committed to an open, inclusive and fair siting process as it seeks an informed willing host community. Continued public engagement and respect for aboriginal rights, treaties and land claims will remain key issues. The implementation

  7. Treatment of advanced, recurrent, resistant to previous treatments basal and squamous cell skin carcinomas with a synergistic formulation of interferons. Open, prospective study

    Directory of Open Access Journals (Sweden)

    Lopez-Saura Pedro

    2009-07-01

    Full Text Available Abstract Background Aggressive non-melanoma skin cancer (deeply infiltrating, recurrent, and morphea form lesions are therapeutically challenging because they require considerable tissue loss and may demand radical disfiguring surgery. Interferons (IFN may provide a non-surgical approach to the management of these tumors. The aim of this work was to evaluate the effect of a formulation containing IFNs-α and -γ in synergistic proportions on patients with recurrent, advanced basal cell (BCC or squamous cell skin carcinomas (SCSC. Methods Patients with extensive, recurrent, resistant to other procedures BCC or SCSC received the IFN formulation peri- and intralesionally, three times per week for 3 weeks. They had been previously treated with surgery and/or radiotherapy or chemotherapy. Thirteen weeks after the end of treatment, the original lesion sites were examined for histological evidence of remaining tumor. Results Sixteen elder (median 70 years-old patients were included. They beared 12 BCC and 4 SCSC ranging from 1.5 to 12.5 cm in the longest dimension. At the end of treatment 47% CR (complete tumor elimination, 40% PR (>30% tumor reduction, and 13% stable disease were obtained. None of the patients relapsed during the treatment period. The median duration of the response was 38 months. Only one patient with complete response had relapsed until today. Principal adverse reactions were influenza-like symptoms well known to occur with interferon therapy, which were well tolerated. Conclusion The peri- and intralesional combination of IFNs-α and -γ was safe and showed effect for the treatment of advanced, recurrent and resistant to previous treatments of BCC and SCSC in elder patients. This is the first report of such treatment in patients with advance non-melanoma skin cancer. The encouraging result justifies further confirmatory trials. Trial registration Current Controlled Trials RPCEC00000052.

  8. Treatment of advanced, recurrent, resistant to previous treatments basal and squamous cell skin carcinomas with a synergistic formulation of interferons. Open, prospective study

    International Nuclear Information System (INIS)

    Anasagasti-Angulo, Lorenzo; Garcia-Vega, Yanelda; Barcelona-Perez, Silvia; Lopez-Saura, Pedro; Bello-Rivero, Iraldo

    2009-01-01

    Aggressive non-melanoma skin cancer (deeply infiltrating, recurrent, and morphea form lesions) are therapeutically challenging because they require considerable tissue loss and may demand radical disfiguring surgery. Interferons (IFN) may provide a non-surgical approach to the management of these tumors. The aim of this work was to evaluate the effect of a formulation containing IFNs-α and -γ in synergistic proportions on patients with recurrent, advanced basal cell (BCC) or squamous cell skin carcinomas (SCSC). Patients with extensive, recurrent, resistant to other procedures BCC or SCSC received the IFN formulation peri- and intralesionally, three times per week for 3 weeks. They had been previously treated with surgery and/or radiotherapy or chemotherapy. Thirteen weeks after the end of treatment, the original lesion sites were examined for histological evidence of remaining tumor. Sixteen elder (median 70 years-old) patients were included. They beared 12 BCC and 4 SCSC ranging from 1.5 to 12.5 cm in the longest dimension. At the end of treatment 47% CR (complete tumor elimination), 40% PR (>30% tumor reduction), and 13% stable disease were obtained. None of the patients relapsed during the treatment period. The median duration of the response was 38 months. Only one patient with complete response had relapsed until today. Principal adverse reactions were influenza-like symptoms well known to occur with interferon therapy, which were well tolerated. The peri- and intralesional combination of IFNs-α and -γ was safe and showed effect for the treatment of advanced, recurrent and resistant to previous treatments of BCC and SCSC in elder patients. This is the first report of such treatment in patients with advance non-melanoma skin cancer. The encouraging result justifies further confirmatory trials. Current Controlled Trials RPCEC00000052

  9. Soil and geologic controls on recharge and groundwater flow response to climate perturbation: A case study of the Yakima River Basin

    Science.gov (United States)

    Nguyen, T. T.; Pham, H. V.; Bachmann, M.; Tague, C.; Adam, J. C.

    2017-12-01

    The Yakima River Basin (YRB) is one of the most important agricultural basins in Washington State with annual revenues in excess of $3.2 billion. This intensively irrigated basin is, however, one of the state's most climatically sensitive water resources system as it heavily relies on winter snowpack and limited reservoir storage. Water shortages and drought are expected to be more frequent with climate change, population growth and increasing agricultural demand. This could result in significant impacts on the groundwater system and subsequently the Yakima River. The goal of this study is to assess how soil and geologic characteristics affect catchment recharge and groundwater flow across three catchments within the YRB using a coupled framework including a physically based hydro-ecological model, the Regional Hydro-Ecologic Simulation System (RHESSys) and a groundwater model, MODFLOW. Soil and geologic-related parameters were randomly sampled to use within the Distributed Evaluation of Local Sensitivity Analysis (DELSA) framework to explore their roles in governing catchment recharge and groundwater flow to climate perturbation. Preliminarily results show that catchment recharge is most sensitive to variation in soil transmissivity in two catchments. However, in the other catchment, recharge is more influenced by soil field capacity and bypass recharge. Recharge is also more sensitive to geologic related parameters in catchments where a portion of its flow comes from deep groundwater. When including the effect of climate perturbations, the sensitivity of recharge responses to soil and geologic characteristics varies with temperature and precipitation change. On the other hand, horizontal hydraulic conductivity is the dominant factor that controls groundwater flow responses in catchments with low permeability soil; alternatively, specific storage (and, to some extent, vertical anisotropy) are important in catchments with more conductive soil. The modeling

  10. The Geologic Story of the Uinta Mountains

    Science.gov (United States)

    Hansen, Wallace R.

    1969-01-01

    The opening of the West after the Civil War greatly stimulated early geologic exploration west of the 100th Meridian. One of the areas first studied, the Uinta Mountains region, gained wide attention as a result of the explorations of three Territorial Surveys, one headed by John Wesley Powell, one by Clarence King, and one by Ferdinand V. Hayden. Completion of the Union Pacific Railroad across southern Wyoming 100 years ago, in 1869, materially assisted geologic exploration, and the railheads at Green River and Rock Springs greatly simplified the outfitting of expeditions into the mountains. The overlap of the Powell, King, and Hayden surveys in the Uinta Mountains led to efforts that were less concerted than competitive and not without acrimony. Many parts of the area were seen by all three parties at almost the same time. Duplication was inevitable, of course, but all three surveys contributed vast quantities of new knowledge to the storehouse of geology, and many now-basic concepts arose from their observations. Powell's area of interest extended mainly southward from the Uinta Mountains to the Grand Canyon, including the boundless plateaus and canyons of southern Utah and northern Arizona. King's survey extended eastward from the High Sierra in California to Cheyenne, Wyoming, and encompassed a swath of country more than 100 miles wide. Hayden's explorations covered an immense region of mountains and basins from Yellowstone Park in Wyoming southeast throughout most of Colorado. Powell first entered the Uinta Mountains in the fall of 1868, having traveled north around the east end of the range from the White River country to Green River, Wyoming, then south over a circuitous route to Flaming Gorge and Browns Park, and finally back to the White River, where he spent the winter. In 1869, after reexamining much of the area visited the previous season, Powell embarked on his famous 'first boat trip' down the Green and Colorado Rivers. This trip was more exploratory

  11. Environmental geology and hydrology

    Science.gov (United States)

    Nakić, Zoran; Mileusnić, Marta; Pavlić, Krešimir; Kovač, Zoran

    2017-10-01

    Environmental geology is scientific discipline dealing with the interactions between humans and the geologic environment. Many natural hazards, which have great impact on humans and their environment, are caused by geological settings. On the other hand, human activities have great impact on the physical environment, especially in the last decades due to dramatic human population growth. Natural disasters often hit densely populated areas causing tremendous death toll and material damage. Demand for resources enhanced remarkably, as well as waste production. Exploitation of mineral resources deteriorate huge areas of land, produce enormous mine waste and pollute soil, water and air. Environmental geology is a broad discipline and only selected themes will be presented in the following subchapters: (1) floods as natural hazard, (2) water as geological resource and (3) the mining and mineral processing as types of human activities dealing with geological materials that affect the environment and human health.

  12. Timing of dose relative to sexual intercourse attempt in previous sildenafil citrate users treated with tadalafil: a geographical comparison from a single arm, open-label study.

    Science.gov (United States)

    Rubio-Aurioles, Eusebio; Glina, Sidney; Abdo, Carmita H N; Hernandez-Serrano, Ruben; Rampazzo, Claudia; Sotomayor, Mariano; West, Teena M; Gallagher, Gabrielle L; Lenero, Enrique

    2009-10-01

    Previous research has demonstrated that sildenafil citrate users alter dosing-sexual attempt behavior when switched to tadalafil. The impact of geography and culture on sexual behavior with phosphodiesterase type 5 (PDE5) inhibitor treatment has not been fully investigated. To describe and compare the changes in dosing-sexual attempt behavior with sildenafil citrate vs. tadalafil treatment across four distinct geographies: Asia, Australia/New Zealand (ANZ), Central Eastern Europe/Middle East (CEE/ME), and Latin America (LA). Data from a single-arm, open-label clinical trial conducted in 21 countries from November 2002 to May 2004 were used in this analysis. Men with erectile dysfunction and a history of > or =6-week prior sildenafil citrate use continued sildenafil citrate treatment for 4 weeks then switched to tadalafil for 8 weeks. Dosing instructions were provided. Timing of dose and sexual intercourse was assessed through patient diaries for the final 4 weeks of each treatment period. A total of 2,760 men were enrolled: Asia 15.8%; ANZ 29.4%; CEE/ME 19.7%; LA 35.1%. The median time from dosing to intercourse was significantly increased during tadalafil treatment across all geographical regions; however, the magnitude of increase differed significantly by geography (P geography. However, the extent to which sexual behavior alters is not uniform across geographical regions, suggesting that dosing instructions and duration of drug effectiveness, in combination with personal and cultural preferences, may determine sexual behavior with PDE5 inhibitor use.

  13. Prognostic factors in multiple myeloma: definition of risk groups in 410 previously untreated patients: a Grupo Argentino de Tratamiento de la Leucemia Aguda study.

    Science.gov (United States)

    Corrado, C; Santarelli, M T; Pavlovsky, S; Pizzolato, M

    1989-12-01

    Four hundred ten previously untreated multiple myeloma patients entered onto two consecutive Grupo Argentino de Tratamiento de la Leucemia Aguda (GATLA) protocols were analyzed to identify significant prognostic factors influencing survival. The univariate analysis selected the following variables: performance status, renal function, percentage of bone marrow plasma cells at diagnosis, hemoglobin, and age. A multivariate analysis showed that performance status, renal function, percentage of bone marrow plasma cells, hemoglobin, and age were the best predictive variables for survival. A score was assigned to each patient according to these variables, which led to their classification in three groups: good, intermediate, and poor risk, with a probability of survival of 26% and 10% at 96 months, and 5% at 56 months, and median survival of 60, 37, and 14 months, respectively (P = .0000). In our patient population, this model proved to be superior to the Durie-Salmon staging system in defining prognostic risk groups, and separating patients with significantly different risks within each Durie-Salmon stage.

  14. Ground penetrating radar geologic field studies of the ejecta of Barringer Meteorite Crater, Arizona, as a planetary analog

    Science.gov (United States)

    Russell, Patrick S.; Grant, John A.; Williams, Kevin K.; Carter, Lynn M.; Brent Garry, W.; Daubar, Ingrid J.

    2013-09-01

    penetrating radar (GPR) has been a useful geophysical tool in investigating a variety of shallow subsurface geological environments on Earth. Here we investigate the capabilities of GPR to provide useful geologic information in one of the most common geologic settings of planetary surfaces, impact crater ejecta. Three types of ejecta are surveyed with GPR at two wavelengths (400 MHz, 200 MHz) at Meteor Crater, Arizona, with the goal of capturing the GPR signature of the subsurface rock population. In order to "ground truth" the GPR characterization, subsurface rocks are visually counted and measured in preexisting subsurface exposures immediately adjacent to and below the GPR transect. The rock size-frequency distribution from 10 to 50 cm based on visual counts is well described by both power law and exponential functions, the former slightly better, reflecting the control of fragmentation processes during the impact-ejection event. GPR counts are found to overestimate the number of subsurface rocks in the upper meter (by a factor of 2-3x) and underestimate in the second meter of depth (0.6-1.0x), results attributable to the highly scattering nature of blocky ejecta. Overturned ejecta that is fractured yet in which fragments are minimally displaced from their complement fragments produces fewer GPR returns than well-mixed ejecta. The use of two wavelengths and division of results into multiple depth zones provides multiple aspects by which to characterize the ejecta block population. Remote GPR measurement of subsurface ejecta in future planetary situations with no subsurface exposure can be used to characterize those rock populations relative to that of Meteor Crater.

  15. Geological field study for science education on Elementary and Junior high school student, in Shimane prefecture, Japan

    Science.gov (United States)

    Matsumoto, I.

    2011-12-01

    The importance of learning at field has been increasing in the elementary and the junior high school in Japan. And, an environmental education is one of the important subjects even in the school education, too. It was important, as for science education, understanding with actual feeling and learning were specified as for the Teaching outlines (the Japanese Ministry of Education, Culture, Sports, Science and Technology) of the new science textbook of the elementary and the junior high school as well. However, It is a little actual situation that there is in an opportunity for the field learning enforced in the school lesson by the investigation of JST (Japan Science and Tecnology Agency). This tendency is strong as much as school of the city and that circumference. I have this cause think that there are a few suitable places for learning to observe geological and biological field near school. In addition, below two is pointed out as a big problem to obstruct the execution of field learning. 1) A natural experience isn't being done sufficient as much as a teacher can teach to the student. 2) It doesn't have the confidence that a teacher teaches a student geology and biology at the field. I introduce the practical example of geological field learning at the public elementary school of the Shimane prefecture by this research. Though it is the place where nature is comparatively rich even in Japan, it can't be said that field learning is popular in Shimane prefecture. A school teacher has to learning experience at field, and he must settle confidence to guide a student at the field. A specialist in the university and the museum must support continuous learning for that to the school teacher.

  16. Recommendations for Conducting Differential Item Functioning (DIF) Analyses for Students with Disabilities Based on Previous DIF Studies. Research Report. ETS RR-11-34

    Science.gov (United States)

    Buzick, Heather; Stone, Elizabeth

    2011-01-01

    The purpose of this study is to help ensure that strategies for differential item functioning (DIF) detection for students with disabilities are appropriate and lead to meaningful results. We surveyed existing DIF studies for students with disabilities and describe them in terms of study design, statistical approach, sample characteristics, and…

  17. Proposals of geological sites for L/ILW and HLW repositories. Geological background. Text volume

    International Nuclear Information System (INIS)

    2008-01-01

    On April 2008, the Swiss Federal Council approved the conceptual part of the Sectoral Plan for Deep Geological Repositories. The Plan sets out the details of the site selection procedure for geological repositories for low- and intermediate-level waste (L/ILW) and high-level waste (HLW). It specifies that selection of geological siting regions and sites for repositories in Switzerland will be conducted in three stages, the first one (the subject of this report) being the definition of geological siting regions within which the repository projects will be elaborated in more detail in the later stages of the Sectoral Plan. The geoscientific background is based on the one hand on an evaluation of the geological investigations previously carried out by Nagra on deep geological disposal of HLW and L/ILW in Switzerland (investigation programmes in the crystalline basement and Opalinus Clay in Northern Switzerland, investigations of L/ILW sites in the Alps, research in rock laboratories in crystalline rock and clay); on the other hand, new geoscientific studies have also been carried out in connection with the site selection process. Formulation of the siting proposals is conducted in five steps: A) In a first step, the waste inventory is allocated to the L/ILW and HLW repositories; B) The second step involves defining the barrier and safety concepts for the two repositories. With a view to evaluating the geological siting possibilities, quantitative and qualitative guidelines and requirements on the geology are derived on the basis of these concepts. These relate to the time period to be considered, the space requirements for the repository, the properties of the host rock (depth, thickness, lateral extent, hydraulic conductivity), long-term stability, reliability of geological findings and engineering suitability; C) In the third step, the large-scale geological-tectonic situation is assessed and large-scale areas that remain under consideration are defined. For the L

  18. Geology of the North Sea and Skagerrak

    Energy Technology Data Exchange (ETDEWEB)

    Michelsen, O. [ed.

    1995-12-31

    The Marine Geology Unit of the Department of Earth Sciences organized the second Marine Geology symposium at Aarhus University, 7-8 October 1993. The intention was to bring together people working especially with the geology of the North Sea and Skagerrak. Approximately 60 people from different Danish and Norwegian institutions attended the symposium. 28 oral presentations were given and 2 posters presented. A large range of geological topics was covered, embracing biostratigraphy, sequence stratigraphy, sedimentology and structural geology. The majority of the presentations dealt with Quaternary geology and Cenozoic sequence stratigraphy, but also Jurassic and Lower Cretaceous stratigraphy was treated. Studies from the major part of the Danish sector were presented, spanning from Bornholm to the central North Sea, and further into the Norwegian North Sea sector. (au)

  19. Prospective monitoring and self-report of previous falls among older women at high risk of falls and fractures: a study of comparison and agreement

    Science.gov (United States)

    Garcia, Patrícia A.; Dias, João M. D.; Silva, Silvia L. A.; Dias, Rosângela C.

    2015-01-01

    Background: The identification of the occurrence of falls is an important step for screening and for rehabilitation processes for the elderly. The methods of monitoring these events are susceptible to recording biases, and the choice of the most accurate method remains challenging. Objectives: (i) To investigate the agreement between retrospective self-reporting and prospective monitoring of methods of recording falls, and (ii) to compare the retrospective self-reporting of falls and the prospective monitoring of falls and recurrent falls over a 12-month period among older women at high risk of falls and fractures. Method: A total of 118 community-dwelling older women with low bone density were recruited. The incidence of falls was monitored prospectively in 116 older women (2 losses) via monthly phone calls over the course of a year. At the end of this monitoring period, the older women were asked about their recall of falls in the same 12-month period. The agreement between the two methods was analyzed, and the sensitivity and specificity of self-reported previous falls in relation to the prospective monitoring were calculated. Results: There was moderate agreement between the prospective monitoring and the retrospective self-reporting of falls in classifying fallers (Kappa=0.595) and recurrent fallers (Kappa=0.589). The limits of agreement were 0.35±1.66 falls. The self-reporting of prior falls had a 67.2% sensitivity and a 94.2% specificity in classifying fallers among older women and a 50% sensitivity and a 98.9% specificity in classifying recurrent fallers. Conclusion: Self-reporting of falls over a 12-month period underestimated 32.8% of falls and 50% of recurrent falls. The findings recommend caution if one is considering replacing monthly monitoring with annual retrospective questioning. PMID:26083603

  20. Long-term clinical and economic outcomes in previously untreated paediatric patients with severe haemophilia A: A nationwide real-world study with 700 person-years.

    Science.gov (United States)

    Vepsäläinen, K; Riikonen, P; Lassila, R; Arola, M; Huttunen, P; Lähteenmäki, P; Möttönen, M; Selander, T; Martikainen, J

    2018-03-01

    For previously untreated patients (PUPs) with severe haemophilia A in Finland for the past 2 decades, the standard practice has been to start early primary prophylaxis. We evaluated the long-term clinical outcomes and costs of treatment with high-dose prophylaxis in PUPs from birth to adolescence, including immune tolerance induction (ITI). From the medical records of all PUPs born between June 1994 and May 2013 in Finland, we retrospectively extracted data on clinical outcomes and healthcare use. Using linear mixed models, we analysed longitudinal clinical outcome data. To analyse skewed cost data, including zero costs, we applied hurdle regression. All 62 patients received early regular prophylaxis; totally, they have had treatment for nearly 700 patient-years. The median age of starting home treatment was 1.1 years. The mean (SD) annual treatment costs (€ per kg) were 4391€ (3852). For ages 1-3, ITI comprised over half of the costs; in other groups, prophylactic FVIII treatment dominated. With these high costs, however, clinical outcomes were desirable; median (IQR) ABR was low at 0.19 (0.07-0.46) and so was AJBR at 0.06 (0-0.24). Thirteen (21%) patients developed a clinically significant inhibitor, 10 (16%) with a high titre. All ITIs were successful. The mean costs for ITI were 383 448€ (259 085). The expected ITI payback period was 1.81 (95% CI 0.62-12.12) years. Early high-dose prophylaxis leads to excellent long-term clinical outcomes, and early childhood ITI therapy seems to turn cost-neutral generally already in 2 years. © 2018 John Wiley & Sons Ltd.

  1. Placental complications after a previous cesarean section

    OpenAIRE

    Milošević Jelena; Lilić Vekoslav; Tasić Marija; Radović-Janošević Dragana; Stefanović Milan; Antić Vladimir

    2009-01-01

    Introduction The incidence of cesarean section has been rising in the past 50 years. With the increased number of cesarean sections, the number of pregnancies with the previous cesarean section rises as well. The aim of this study was to establish the influence of the previous cesarean section on the development of placental complications: placenta previa, placental abruption and placenta accreta, as well as to determine the influence of the number of previous cesarean sections on the complic...

  2. Study of an optimization approach for a disposal tunnel layout, taking into account the geological environment with spatially heterogeneous characteristics

    International Nuclear Information System (INIS)

    Suyama, Yasuhiro; Toida, Masaru; Yanagizawa, Koichi

    2009-01-01

    The geological environment has spatially heterogeneous characteristics with varied host rock types, fractures and so on. In this case the generic disposal tunnel layout, which has been designed by JNC, is not the most suitable for HLW disposal in Japan. The existence of spatially heterogeneous characteristics means that in the repository region there exist sub-regions that are more favourable from the perspective of long-term safety and ones that are less favourable. In order that the spatially heterogeneous environment itself may be utilized most effectively as a natural barrier system, an alternative design of disposal tunnel layout is required. Focusing on the geological environment with spatially heterogeneous characteristics, the authors have developed an alternative design of disposal tunnel layout. The alternative design adopts an optimization approach using a variable disposal tunnel layout. The optimization approach minimizes the number of locations where major water-conducting fractures are intersected, and maximizes the number of emplacement locations for waste packages. This paper will outline the variable disposal tunnel layout and its applicability.

  3. The Geology of the Marcia Quadrangle of Asteroid 4Vesta: An Integrated Mapping Study Using Dawn Spacecraft Data

    Science.gov (United States)

    Williams, David A.; Denevi, B. W.; Mittlefehldt, D. W.; Mest, S. C.; Schenk, P. M.; Jaumann, R.; DeSanctis, M. C.; Buczkowski, D. L.; Ammannito, E.; Prettyman, T. H.; hide

    2012-01-01

    We used geologic mapping applied to Dawn data as a tool to understand the geologic history of the Marcia quadrangle of Vesta. This region hosts a set of relatively fresh craters and surrounding ejecta field, an unusual dark hill named Arisia Tholus, and a orange (false color) diffuse material surrounding the crater Octavia. Stratigraphically, from oldest to youngest, three increasingly larger impact craters named Minucia, Calpurnia, and Marcia make up a snowmanlike feature, which is surrounded by a zone of dark material interpreted to consist of impact ejecta and possibly impact melts. The floor of Marcia contains a pitted terrain thought to be related to release of volatiles (1). The dark ejecta field has an enhanced signature of H, possibly derived from carbonaceous chondritic material that accumulated in Vesta s crust (2,3). The dark ejecta has a spectrally distinctive behavior with shallow pyroxenes band depths. Outside the ejecta field this quadrangle contains various cratered terrains, with increasing crater abundance moving south to north away from the Rheasilvia basin. Arisia Tholus, originally suggested as an ancient volcano, appears to be an impact-sculpted basin rim fragment with a superposed darkrayed impact crater. There remains no unequivocal evidence of volcanic features on Vesta s surface, likely because basaltic material of the HED meteorite suite demonstrates magmatism ended very early on Vesta (4). Ongoing work includes application of crater statistical techniques to obtain model ages of surface units, and more detailed estimates of the compositional variations among the surface units.

  4. Geological evolution of the center-southern portion of the Guyana shield based on the geochemical, geochronological and isotopic studies of paleoproterozoic granitoids from southeastern Roraima, Brazil

    International Nuclear Information System (INIS)

    Almeida, Marcelo Esteves

    2006-01-01

    This study focuses the granitoids of center-southern portion of Guyana Shield, southeastern Roraima, Brazil. The region is characterized by two tectonic-stratigraphic domains, named as Central Guyana (GCD) and Uatuma-Anaua (UAD) and located probably in the limits of geochronological provinces (e.g. Ventuari-Tapajos or Tapajos-Parima, Central Amazonian and Maroni-Itacaiunas or Transamazon). The aim this doctoral thesis is to provide new petrological and lithostratigraphic constraints on the granitoid rocks and contribute to a better understanding of the origin and geo dynamic evolution of Guyana Shield. The GCD is only locally studied near to the UAD boundary, and new geological data and two single zircon Pb-evaporation ages in mylonitic biotite granodiorite (1.89 Ga) and foliated hastingsite-biotite granite (1.72 Ga) are presented. These ages of the protholiths contrast with the lithostratigraphic picture in the other areas of Cd (1.96-1.93 Ga). Regional mapping, petrography, geochemistry and zircon geochronology carried out in the Urad have showed widespread Paleoproterozoic calc-alkaline granitic magmatism. These granitoid rocks are distributed into several magmatic associations with different Paleoproterozoic (1.97-1.89 Ga) ages, structural and geochemical affinities. Detailed mapping, petrographic and geochronological studies have distinguished two main sub domains in the UAD. In the northern UAD, the high-K calc-alkaline Martins Pereira (1.97 Ga) and Serra Dourada S-type granites (1.96 Ga) are affected by NE-SW and E-W ductile dextral shear-zones, showing coexistence of magmatic and deformational fabrics related to heterogeneous deformation. Inliers of basement (2.03 Ga) crop out northeast of this area, and are formed by meta volcano-sedimentary sequence (Cauarane Group) and TTG-like calc-alkaline association (Anaua Complex). Xenoliths of meta diorites (Anaua Complex) and para gneisses (Cauarane Group) reinforce the intrusive character of Martins Pereira

  5. Geological exploration of Angola from Sumbe to Namibe: A review at the frontier between geology, natural resources and the history of geology

    Science.gov (United States)

    Masse, Pierre; Laurent, Olivier

    2016-01-01

    This paper provides a review of the Geological exploration of the Angola Coast (from Sumbe to Namibe) from pioneer's first geological descriptions and mining inventory to the most recent publications supported by the oil industry. We focus our attention on the following periods: 1875-1890 (Paul Choffat's work, mainly), 1910-1949 (first maps at country scale), 1949-1974 (detailed mapping of the Kwanza-Namibe coastal series), 1975-2000, with the editing of the last version of the Angola geological map at 1:1 million scale and the progressive completion of previous works. Since 2000, there is a renewal in geological fieldwork publications on the area mainly due to the work of university teams. This review paper thus stands at the frontier between geology, natural resources and the history of geology. It shows how geological knowledge has progressed in time, fueled by economic and scientific reasons.

  6. A Comparative Study of the Previously Graduated Dentists' Knowledge versus those Recently Graduated as to Proper Prescription of Interaoral Radiography and Panoramic Views

    OpenAIRE

    Bardal R.; Rahimi R.; Ahmadi Motamayel F.

    2011-01-01

    Statement of Problems: The first step to decrease the patients' exposure to unnecessary radiography radiation is the proper prescription of radiography. . Purpose: The purpose of this study was to evaluate the knowledge of general dental practitioners as to proper prescription of intraoral radiography and panoramic views. Materials and Method: In this study, a questionnaire on the dentists' knowledge about the proper prescription of dental radiography was used. A total of eighty one general d...

  7. The change in motivating factors influencing commencement, adherence and retention to a supervised resistance training programme in previously sedentary post-menopausal women: a prospective cohort study.

    Science.gov (United States)

    Viljoen, Janet Erica; Christie, Candice Jo-Anne

    2015-03-12

    Understanding motivators for exercise participation in post-menopausal women may impact retention to exercise programmes and inform intervention trial designs. The purpose of this investigation was to assess self-reported motivational factors influencing adherence and retention to a 24-week progressive resistance training programme. Post-menopausal females (n = 34) were passively recruited to undertake a 24-week progressive resistance training protocol, in small-group sessions, on three non-consecutive days of the week. Attendance was recorded by the researcher. Qualitative reports were sourced from the sample for four phases of the study: pre-study (prior to week 1), recruitment (week 1), during study (weeks 2 - 24), and post-intervention (beyond week 24). Responses were categorised according to ten descriptors: specific health index improvement, education, flexibility of time, social contact, conscience (loyalty to the researcher), wellness, weight management, organisation parameters (pertaining to the study programme) and enjoyment of the exercises. Of the initial sample, 76.5% (n = 26) met the specified ≥80% attendance criterion. The primary findings were that motivation to volunteer for the study was driven by a perceived need for a structured exercise programme (50% of respondents). A commitment to the researcher was the primary motivator for continued adherence to the study for 50% of participants. Social contact with other participants was cited by 60% of the sample as the primary reason for adherence for the full duration of 24 weeks. A desire to maintain the "wellness" derived from the programme was cited by 60% as a reason for continuing an exercise routine post-study. This study identified that routine and supervision initially attract women to exercise programmes, while social cohesion of the group setting contributes to retention over time. Understanding the changing nature of motivating factors may contribute to better overall adherence

  8. Preliminary Mariner 9 report on the geology of Mars.

    Science.gov (United States)

    Mccauley, J. F.; Carr, M. H.; Masursky, H.; Milton, D. J.; Wilhelms, D. E.; Cutts, J. A.; Hartmann, W. K.; Sharp, R. P.

    1972-01-01

    Mariner 9 results indicate that Mars is geologically far more heterogeneous than previously suspected from earlier flyby missions; the surface has been shaped by volcanic, tectonic, erosional, and depositional activity. The equatorial region between 30 deg N and 30 deg S latitude is depicted in four geologic sketch maps, and seventeen geologic units are defined on the basis of their textural characteristics. The maps and the brief descriptions of geological units portrayed are followed by a series of more interpretive discussions dealing with topical problems and a summary geologic history. Topics covered include cratering, circular basins, volcanism, canyons, chaotic terrain, channels, and eolian activity.

  9. Application of Multi-level Grey Evaluation on Geological Tourism Resources’ Economic Values of Geopark: A Case Study of Huashan Geopark in Shaanxi Province

    Science.gov (United States)

    Zhang, Yang; Gong, Xianjie

    2018-01-01

    Geo-park gives priority to geographical relic landscapes. It has not only rich geological touristic resources but also extraordinarily high values for economic development. Taking Huashan Geological Park as an example, the thesis systematically analyzes the characteristics of the geological touristic resources in this park. It applies the method of multilevel grey evaluation to establish the evaluation model for the economic values of the touristic resources in the geological park and presents detailed result of the assessment. The result concludes an excellent grade for the comprehensive evaluation of the economic values of Huashan geological touristic resources, reflecting the outstanding natural advantages of the park in geological resources. Moreover, in the single-item evaluations, the scientific evaluation ranks the highest in score, indicating that the geological touristic resources of the park have extraordinary geologically science-popularizing values as a significant condition for the development of scientific tours. It shows that the park is endowed with excellent prospects for economic development.

  10. Experimental study and modelling of physico-chemical mechanisms of clay-concrete interactions in the radioactive waste geological disposal context

    International Nuclear Information System (INIS)

    Dauzeres, A.

    2010-09-01

    These research works are carried out as part of the radioactive wastes geological disposal feasibility study. The current option developed by Andra, includes several cementitious materials in contact with the surrounding Callovo-Oxfordian (COX) (an argillite). Concretes and argillite present very different pore solutions (ionic concentrations and pH). Controlled by the concentrations differences, the aqueous species diffusion in the solids generates chemical and physical disturbances. This study is based on experimental, analytical and numerical works, in order to identify the mechanisms controlling the clayey environment influence on cementitious materials. (author)

  11. Geologic study of the interior Salt Domes of Northeast Texas Salt-Dome basin to investigate their suitability for possible storage of radioactive waste material

    International Nuclear Information System (INIS)

    1976-05-01

    The purpose of this study was to investigate the movement and hydrologic stability of the domes, to identify the domes which appear suitable for further study and consideration, and to outline the additional information needed to evaluate these domes. The growth of the interior salt domes appears to have slowed with geologic time and to have halted altogether. The Bullard, Whitehouse, and Keechi domes probably are not subject to significant dissolution at the present time. However, caprock found at Bullard and Whitehouse indicates that salt dissolution occurred at some period during the past 50 million years since Wilcox was deposited. It is recommended that shallow water wells be drilled and tested

  12. The possibility of previous epidemiological data to serve as baseline for future national oral health surveys--a study in Vietnam.

    NARCIS (Netherlands)

    Palenstein Helderman, W.H. van; Truin, G.J.; Can, N.; Khanh, N.D.

    2001-01-01

    AIM: The purpose of this paper is to review the most recent epidemiological data (1985-2000) on dental caries and periodontal diseases in Vietnam in an attempt to obtain a 'baseline' for future national oral health surveys. METHODS: Studies on periodontal diseases and caries were included when CPITN

  13. Does hyperbaric oxygen treatment have the potential to increase salivary flow rate and reduce xerostomia in previously irradiated head and neck cancer patients? A pilot study

    DEFF Research Database (Denmark)

    Forner, Lone; Hansen, Ole Hyldegaard; von Brockdorff, Annet Schack

    2011-01-01

    Irradiated head and neck cancer survivors treated in the Hyperbaric Oxygen (HBO) Unit, Copenhagen University Hospital, spontaneously reported improvement of radiation-induced dry mouth feeling. The aim of this pilot study was to evaluate salivary flow rate and xerostomia before and after HBO...

  14. AEGIS geologic simulation model

    International Nuclear Information System (INIS)

    Foley, M.G.

    1982-01-01

    The Geologic Simulation Model (GSM) is used by the AEGIS (Assessment of Effectiveness of Geologic Isolation Systems) program at the Pacific Northwest Laboratory to simulate the dynamic geology and hydrology of a geologic nuclear waste repository site over a million-year period following repository closure. The GSM helps to organize geologic/hydrologic data; to focus attention on active natural processes by requiring their simulation; and, through interactive simulation and calibration, to reduce subjective evaluations of the geologic system. During each computer run, the GSM produces a million-year geologic history that is possible for the region and the repository site. In addition, the GSM records in permanent history files everything that occurred during that time span. Statistical analyses of data in the history files of several hundred simulations are used to classify typical evolutionary paths, to establish the probabilities associated with deviations from the typical paths, and to determine which types of perturbations of the geologic/hydrologic system, if any, are most likely to occur. These simulations will be evaluated by geologists familiar with the repository region to determine validity of the results. Perturbed systems that are determined to be the most realistic, within whatever probability limits are established, will be used for the analyses that involve radionuclide transport and dose models. The GSM is designed to be continuously refined and updated. Simulation models are site specific, and, although the submodels may have limited general applicability, the input data equirements necessitate detailed characterization of each site before application

  15. Alfalfa (Medicago sativa L.) is tolerant to higher levels of salinity than previous guidelines indicated: Implications of field and greenhouse studies

    Science.gov (United States)

    Putnam, Daniel H.; Benes, Sharon; Galdi, Giuliano; Hutmacher, Bob; Grattan, Steve

    2017-04-01

    Alfalfa (Medicago sativa L.) is the most widely grown leguminous forage crop in North America and is valued for high productivity, quality, economic value, and for dairy productivity. Alfalfa has historically been classified as moderately sensitive to saline conditions, with yield declines predicted at >2 dS/m in the saturated soil paste extract. However, greenhouse, sand tank, and field studies over the past five years have confirmed that alfalfa can be grown with limited negative effects at much higher salinity levels. A broad collection of alfalfa varieties has exhibited a range of resistance at irrigation water salinities >5 dS/m ECw in greenhouse trials, with significant variation due to variety. USDA-ARS sand tank studies indicated similar or greater tolerances closer to 8 dS/m in the soil water, in addition to confirmation of significant varietal differences. A three-year field study on clay loam soil with applications of 5-7 dS/m ECw irrigation water indicated normal yields and excellent stand survivability. A second field study in the same soil type with levels from 8-10 dS/m ECw showed yield reductions of 10-15% but economic yields were still achieved at those levels. Field and greenhouse studies were conducted with mixed salt saline sodic waters typical of the San Joaquin Valley of California. Field evaluation of variety performance was subject to greater variation due to secondary salinity-soil interactions including water infiltration and crusting problems, not only salinity per-se. Thus, adequate irrigation water availability to the crop may be as important as salinity in impacting yields under field conditions. Once established, the deep-rooted characteristics of alfalfa enable utilization of deeper subsurface moisture, even at moderate to high salinity levels, as documented by USDA lysimeter studies. Significant advantages to salinity-tolerant varieties have been observed. It will be important to consider specific management factors which may enable

  16. InteractInteraction mechanism of emergency response in geological hazard perception and risk management: a case study in Zhouqu county

    Science.gov (United States)

    Qi, Yuan; Zhao, Hongtao

    2017-04-01

    China is one of few several natural disaster prone countries, which has complex geological and geographical environment and abnormal climate. On August 8, 2010, a large debris flow disaster happened in Zhouqu Country, Gansu province, resulting in more than 1700 casualties and more than 200 buildings damaged. In order to percept landslide and debris flow, an early warning system was established in the county. Spatial information technologies, such as remote sensing, GIS, and GPS, play core role in the early warning system, due to their functions in observing, analyzing, and locating geological disasters. However, all of these spatial information technologies could play an important role only guided by the emergency response mechanism. This article takes the establishment of Zhouqu Country's Disaster Emergency Response Interaction Mechanism (DERIM) as an example to discuss the risk management of country-level administrative units. The country-level risk management aims to information sharing, resources integration, integrated prevention and unified command. Then, nine subsystems support DERIM, which included disaster prevention and emergency data collection and sharing system, joint duty system, disaster verification and evaluation system, disaster consultation system, emergency warning and information release system, emergency response system, disaster reporting system, plan management system, mass prediction and prevention management system. At last, an emergency command platform in Zhouqu Country built up to realize DERIM. The core mission of the platform consists of daily management of disaster, monitoring and warning, comprehensive analysis, information release, consultation and decision-making, emergency response, etc. Five functional modules, including module of disaster information management, comprehensive monitoring module (geological monitoring, meteorological monitoring, water conservancy and hydrological monitoring), alarm management module, emergency

  17. Effect of benzalkonium chloride?free travoprost on intraocular pressure and ocular surface symptoms in patients with glaucoma previously on latanoprost: an open-label study

    OpenAIRE

    Lopes, Joao F.; Hubatsch, Douglas A.; Amaris, Patricia

    2015-01-01

    Background Prostaglandin analogs reduce intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension; however, these medications may affect the ocular surface and elicit ocular discomfort when preserved with benzalkonium chloride (BAK). Methods This was an open-label, single-arm study conducted in Latin America from February 2012 to May 2013. Patients with open-angle glaucoma or ocular hypertension who were intolerant of latanoprost 0.005?% were transitioned to recei...

  18. Field Geology/Processes

    Science.gov (United States)

    Allen, Carlton; Jakes, Petr; Jaumann, Ralf; Marshall, John; Moses, Stewart; Ryder, Graham; Saunders, Stephen; Singer, Robert

    1996-01-01

    The field geology/process group examined the basic operations of a terrestrial field geologist and the manner in which these operations could be transferred to a planetary lander. Four basic requirements for robotic field geology were determined: geologic content; surface vision; mobility; and manipulation. Geologic content requires a combination of orbital and descent imaging. Surface vision requirements include range, resolution, stereo, and multispectral imaging. The minimum mobility for useful field geology depends on the scale of orbital imagery. Manipulation requirements include exposing unweathered surfaces, screening samples, and bringing samples in contact with analytical instruments. To support these requirements, several advanced capabilities for future development are recommended. Capabilities include near-infrared reflectance spectroscopy, hyper-spectral imaging, multispectral microscopy, artificial intelligence in support of imaging, x ray diffraction, x ray fluorescence, and rock chipping.

  19. A multicenter phase I/II study of obatoclax mesylate administered as a 3- or 24-hour infusion in older patients with previously untreated acute myeloid leukemia.

    Directory of Open Access Journals (Sweden)

    Aaron D Schimmer

    Full Text Available An open-label phase I/II study of single-agent obatoclax determined a maximum tolerated dose (MTD and schedule, safety, and efficacy in older patients (≥ 70 yr with untreated acute myeloid leukemia (AML.Phase I evaluated the safety of obatoclax infused for 3 hours on 3 consecutive days (3 h × 3 d in 2-week cycles. Initial obatoclax dose was 30 mg/day (3 h × 3 d; n = 3. Obatoclax was increased to 45 mg/day (3 h × 3 d if ≤ 1 patient had a dose-limiting toxicity (DLT and decreased to 20 mg/day (3 h × 3 d if DLT occurred in ≥ 2 patients. In the phase II study, 12 patients were randomized to receive obatoclax at the dose identified during phase I (3 h × 3 d or 60 mg/day administered by continuous infusion over 24 hours for 3 days (24 h × 3 d to determine the morphologic complete response rate.In phase I, two of three patients receiving obatoclax 30 mg/day (3 h × 3 d experienced grade 3 neurologic DLTs (confusion, ataxia, and somnolence. Obatoclax was decreased to 20 mg/day (3 h × 3 d. In phase II, no clinically relevant safety differences were observed between the 20 mg/day (3 h × 3 d; n = 7 and 60 mg/day (24 h × 3 d; n = 5 arms. Neurologic and psychiatric adverse events were most common and were generally transient and reversible. Complete response was not achieved in any patient.Obatoclax 20 mg/day was the MTD (3 h × 3 d in older patients with AML. In the schedules tested, single-agent obatoclax was not associated with an objective response. Evaluation in additional subgroups or in combination with other chemotherapy modalities may be considered for future study.ClinicalTrials.gov NCT00684918.

  20. A multicenter phase I/II study of obatoclax mesylate administered as a 3- or 24-hour infusion in older patients with previously untreated acute myeloid leukemia.

    Science.gov (United States)

    Schimmer, Aaron D; Raza, Azra; Carter, Thomas H; Claxton, David; Erba, Harry; DeAngelo, Daniel J; Tallman, Martin S; Goard, Carolyn; Borthakur, Gautam

    2014-01-01

    An open-label phase I/II study of single-agent obatoclax determined a maximum tolerated dose (MTD) and schedule, safety, and efficacy in older patients (≥ 70 yr) with untreated acute myeloid leukemia (AML). Phase I evaluated the safety of obatoclax infused for 3 hours on 3 consecutive days (3 h × 3 d) in 2-week cycles. Initial obatoclax dose was 30 mg/day (3 h × 3 d; n = 3). Obatoclax was increased to 45 mg/day (3 h × 3 d) if ≤ 1 patient had a dose-limiting toxicity (DLT) and decreased to 20 mg/day (3 h × 3 d) if DLT occurred in ≥ 2 patients. In the phase II study, 12 patients were randomized to receive obatoclax at the dose identified during phase I (3 h × 3 d) or 60 mg/day administered by continuous infusion over 24 hours for 3 days (24 h × 3 d) to determine the morphologic complete response rate. In phase I, two of three patients receiving obatoclax 30 mg/day (3 h × 3 d) experienced grade 3 neurologic DLTs (confusion, ataxia, and somnolence). Obatoclax was decreased to 20 mg/day (3 h × 3 d). In phase II, no clinically relevant safety differences were observed between the 20 mg/day (3 h × 3 d; n = 7) and 60 mg/day (24 h × 3 d; n = 5) arms. Neurologic and psychiatric adverse events were most common and were generally transient and reversible. Complete response was not achieved in any patient. Obatoclax 20 mg/day was the MTD (3 h × 3 d) in older patients with AML. In the schedules tested, single-agent obatoclax was not associated with an objective response. Evaluation in additional subgroups or in combination with other chemotherapy modalities may be considered for future study. ClinicalTrials.gov NCT00684918.

  1. Effect of benzalkonium chloride-free travoprost on intraocular pressure and ocular surface symptoms in patients with glaucoma previously on latanoprost: an open-label study.

    Science.gov (United States)

    Lopes, Joao F; Hubatsch, Douglas A; Amaris, Patricia

    2015-11-12

    Prostaglandin analogs reduce intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension; however, these medications may affect the ocular surface and elicit ocular discomfort when preserved with benzalkonium chloride (BAK). This was an open-label, single-arm study conducted in Latin America from February 2012 to May 2013. Patients with open-angle glaucoma or ocular hypertension who were intolerant of latanoprost 0.005 % were transitioned to receive once-daily BAK-free travoprost 0.004 % containing polyquaternium-1 (Travatan® preserved with POLYQUAD® [PQ], Alcon Laboratories, Inc; Fort Worth, TX) for 12 weeks. Mean change in IOP from baseline (primary efficacy endpoint) and the percentage of patients who achieved a target IOP of ≤18 mmHg were evaluated at all on-therapy visits. Ocular hyperemia, patient preference, and self-projected adherence were assessed at week 12. Adverse events (AEs) were monitored throughout the study. All enrolled patients were included in the analysis (n = 191); the majority of patients (90.6 %, n = 173/191) completed the study. Mean (SD) patient age was 67.5 (11.3) years, and mean baseline IOP was 14.8 mmHg. Mean IOP was reduced by 0.94 mmHg at week 6 and by 1.09 mmHg at week 12 (P glaucoma or ocular hypertension who were intolerant of latanoprost. BAK-free travoprost 0.004 % is a viable alternative for patients who require switching their IOP-lowering medications because of tolerability issues. ClinicalTrials.gov identifier, NCT01510145.

  2. Summary of U.S. Geological Survey studies conducted in cooperation with the Citizen Potawatomi Nation, central Oklahoma, 2011–14

    Science.gov (United States)

    Andrews, William J.; Becker, Carol J.; Ryter, Derek W.; Smith, S. Jerrod

    2016-01-19

    The U.S. Geological Survey conducted hydrologic studies and published three U.S. Geological Survey scientific investigations reports in cooperation with the Citizen Potawatomi Nation from 2011 to 2014 to characterize the quality and quantity of water resources. The study areas of those reports consisted of approximately 960 square miles in parts of three counties in central Oklahoma. This study area has multiple abundant sources of water, being underlain by three principal aquifers (alluvial/terrace, Central Oklahoma, and Vamoosa-Ada), being bordered by two major rivers (North Canadian and Canadian), and having several smaller drainages including the Little River in the central part of the study area and Salt Creek in the southeastern part of the study area. The Central Oklahoma aquifer (also referred to as the “Garber-Wellington aquifer”) underlies approximately 3,000 square miles in central Oklahoma in parts of Cleveland, Logan, Lincoln, Oklahoma, and Pottawatomie Counties and much of the study area. Water from these aquifers is used for municipal, industrial, commercial, agricultural, and domestic supplies.

  3. Tendon Length, Calf Muscle Atrophy, and Strength Deficit After Acute Achilles Tendon Rupture: Long-Term Follow-up of Patients in a Previous Study.

    Science.gov (United States)

    Heikkinen, Juuso; Lantto, Iikka; Piilonen, Juuso; Flinkkilä, Tapio; Ohtonen, Pasi; Siira, Pertti; Laine, Vesa; Niinimäki, Jaakko; Pajala, Ari; Leppilahti, Juhana

    2017-09-20

    In this prospective study, we used magnetic resonance imaging (MRI) to assess long-term Achilles tendon length, calf muscle volume, and muscle fatty degeneration after surgery for acute Achilles tendon rupture. From 1998 to 2001, 60 patients at our center underwent surgery for acute Achilles tendon rupture followed by early functional postoperative rehabilitation. Fifty-five patients were reexamined after a minimum duration of follow-up of 13 years (mean, 14 years), and 52 of them were included in the present study. Outcome measures included Achilles tendon length, calf muscle volume, and fatty degeneration measured with MRI of both the affected and the uninjured leg. The isokinetic plantar flexion strength of both calves was measured and was correlated with the structural findings. The Achilles tendon was, on average, 12 mm (95% confidence interval [CI] = 8.6 to 15.6 mm; p muscles were 63 cm (13%; p muscle atrophy. Increased Achilles tendon length is associated with smaller calf muscle volumes and persistent plantar flexion strength deficits after surgical repair of Achilles tendon rupture. Strength deficits and muscle volume deficits are partly compensated for by FHL hypertrophy, but 11% to 13% deficits in soleus and gastrocnemius muscle volumes and 12% to 18% deficits in plantar flexion strength persist even after long-term follow-up. Therapeutic Level II. See Instructions for Authors for a complete description of levels of evidence.

  4. Outcomes following detection of low level plasma HIV RNA in HIV-infected patients previously virologically suppressed on antiretroviral therapy: a retrospective observational study.

    Science.gov (United States)

    Warren, Annabelle M; Cheng, Allen C; Watson, Kerrie; Lewin, Sharon R; Hoy, Jennifer F

    2017-06-01

    Progressively sensitive assays for plasma HIV RNA have led to increased detection of plasma HIV RNA between 20 and 200 copies/ml, known as low level viremia (LLV) when recurrent or persistent, in HIV-infected patients on antiretroviral therapy (ART). The aim of this study was to determine outcomes following initial detection of LLV in an Australian cohort. A retrospective study using the HIV Service Database (Alfred Hospital) included all patients on ART who recorded plasma HIV RNA 20-200 copies/mL following prior virological suppression (viral load (VL) HIV RNA 200 copies/mL. Factors associated with LLV included co-morbid type 2 diabetes, shorter prior virological suppression and lower nadir CD4 cell count. Clinician management of VL 20-200 copies/mL was generally conservative, with infrequent requests for genotypic analysis (3.3% cases) or change in ART (<1% cases). LLV following virological suppression is common, and occurred as an isolated viral blip in half the patients. Those patients with persistent or recurrent LLV had higher rates of type 2 diabetes, shorter prior virological suppression and lower nadir CD4 cell count.

  5. Potential uses of stable isotope ratios of Sr, Nd, and Pb in geological materials for environmental studies.

    Science.gov (United States)

    Nakano, Takanori

    2016-01-01

    The ratios of stable isotopes of certain elements in rocks and minerals have strong regional characteristics that are reflected in atmospheric components, in water, and in the living organisms that form Earth's surface environment as well as in agricultural and fishery products. Geologically derived stable isotope ratios can be used as a tracer for the source of many kinds of substances, with current geochemical techniques allowing the precise determination of numerous stable isotope ratios in both natural and manmade objects. This review presents examples of the use of stable isotopes as tracers within diverse dynamic ecosystems, focusing on Sr isotopes but also including examples of Nd and Pb isotopic analysis, and reviewing the potential of this technique for a wide range of environmental research, including determining the geographic origin of food and archeological materials.

  6. Potential uses of stable isotope ratios of Sr, Nd, and Pb in geological materials for environmental studies

    Science.gov (United States)

    NAKANO, Takanori

    2016-01-01

    The ratios of stable isotopes of certain elements in rocks and minerals have strong regional characteristics that are reflected in atmospheric components, in water, and in the living organisms that form Earth’s surface environment as well as in agricultural and fishery products. Geologically derived stable isotope ratios can be used as a tracer for the source of many kinds of substances, with current geochemical techniques allowing the precise determination of numerous stable isotope ratios in both natural and manmade objects. This review presents examples of the use of stable isotopes as tracers within diverse dynamic ecosystems, focusing on Sr isotopes but also including examples of Nd and Pb isotopic analysis, and reviewing the potential of this technique for a wide range of environmental research, including determining the geographic origin of food and archeological materials. PMID:27302069

  7. Global Journal of Geological Sciences

    African Journals Online (AJOL)

    Global Journal of Geological Sciences is aimed at promoting research in all areas of Geological Sciences including geochemistry, geophysics, engineering geology, hydrogeology, petrology, mineralogy, geochronology, tectonics, mining, structural geology, marine geology, space science etc. Visit the Global Journal Series ...

  8. Responses to A(H1N1)pdm09 influenza vaccines in participants previously vaccinated with seasonal influenza vaccine: a randomized, observer-blind, controlled study.

    Science.gov (United States)

    Roy-Ghanta, Sumita; Van der Most, Robbert; Li, Ping; Vaughn, David W

    2014-11-01

    Prior receipt of a trivalent seasonal influenza vaccine (TIV) can affect hemagglutination inhibition (HI) antibody responses to pandemic influenza vaccines. We investigated the effect of TIV priming on humoral responses to AS03-adjuvanted and nonadjuvanted A(H1N1)pdm09 vaccines, the role of AS03 on cell-mediated immune (CMI) responses, and vaccine safety. Healthy adults (aged 19-40 years) were randomized 1:1:1:1 to receive TIV or saline followed 4 months later by 2 doses, 3 weeks apart, of adjuvanted or nonadjuvanted A(H1N1)pdm09 vaccine and followed up to study end (day 507). Pre- and postvaccination responses of HI and neutralizing antibody, CD4(+)/CD8(+) T cells, memory B cells, and plasmablasts were assessed. Ninety-nine of the 133 participants enrolled completed the study. No vaccine-related serious adverse events were recorded. In TIV-primed participants, A(H1N1)pdm09-specific antibody and CD4(+) T-cell and memory B-cell responses to the pandemic vaccine tended to be diminished. Vaccine adjuvantation led to increased responses of vaccine-homologous and -heterologous HI and neutralizing antibodies and CD4(+) T cells, homologous memory B cells, and plasmablasts. In healthy adults, prior TIV administration decreased humoral and CMI responses to A(H1N1)pdm09 vaccine. Adjuvantation of A(H1N1)pdm09 antigen helped to overcome immune interference between the influenza vaccines. No safety concerns were observed. Clinical Trials.gov identifier NCT00707967. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America.

  9. Responses to A(H1N1)pdm09 Influenza Vaccines in Participants Previously Vaccinated With Seasonal Influenza Vaccine: A Randomized, Observer-Blind, Controlled Study

    Science.gov (United States)

    Roy-Ghanta, Sumita; Van der Most, Robbert; Li, Ping; Vaughn, David W.

    2014-01-01

    Background. Prior receipt of a trivalent seasonal influenza vaccine (TIV) can affect hemagglutination inhibition (HI) antibody responses to pandemic influenza vaccines. We investigated the effect of TIV priming on humoral responses to AS03-adjuvanted and nonadjuvanted A(H1N1)pdm09 vaccines, the role of AS03 on cell-mediated immune (CMI) responses, and vaccine safety. Methods. Healthy adults (aged 19–40 years) were randomized 1:1:1:1 to receive TIV or saline followed 4 months later by 2 doses, 3 weeks apart, of adjuvanted or nonadjuvanted A(H1N1)pdm09 vaccine and followed up to study end (day 507). Pre- and postvaccination responses of HI and neutralizing antibody, CD4+/CD8+ T cells, memory B cells, and plasmablasts were assessed. Results. Ninety-nine of the 133 participants enrolled completed the study. No vaccine-related serious adverse events were recorded. In TIV-primed participants, A(H1N1)pdm09-specific antibody and CD4+ T-cell and memory B-cell responses to the pandemic vaccine tended to be diminished. Vaccine adjuvantation led to increased responses of vaccine-homologous and -heterologous HI and neutralizing antibodies and CD4+ T cells, homologous memory B cells, and plasmablasts. Conclusions. In healthy adults, prior TIV administration decreased humoral and CMI responses to A(H1N1)pdm09 vaccine. Adjuvantation of A(H1N1)pdm09 antigen helped to overcome immune interference between the influenza vaccines. No safety concerns were observed. Registration. Clinical Trials.gov identifier NCT00707967. PMID:24864125

  10. Massive sulfide exploration models of the Iberian Pyrite Belt Neves Corvo mine region, based in a 3D geological, geophysical and geochemical ProMine study

    Science.gov (United States)

    Inverno, Carlos; Matos, João Xavier; Rosa, Carlos; Mário Castelo-Branco, José; Granado, Isabel; Carvalho, João; João Baptista, Maria; Represas, Patrícia; Pereira, Zélia; Oliveira, Tomás; Araujo, Vitor

    2013-04-01

    The Iberian Pyrite Belt (IPB) hosts one of the largest concentrations of massive sulfides in the Earth's crust. This highly productive VMS belt contains more than 85 massive sulfide deposits, totalling an estimate of 1600 Mt of massive ore and about 250 Mt of stockwork ore (Leistel et al., 1998; Oliveira et al., 2005; Tornos, 2006). Included in the South Portuguese Zone the IPB is represented by the Phyllite-Quartzite Group (PQG) composed of shales and quartzites of late Devonian age followed by the Volcanic-Sedimentary Complex (VSC) a submarine succession of sediments and felsic and basic volcanic rocks (late Famennian-late Viséan age). Above the IPB a turbidite sedimentary unit occurs being represented by the Baixo Alentejo Flysch Group (BAFG). The ore deposits are hosted by felsic volcanic rocks and sediments that are dominant in the lower part of the VSC succession. The Neves Corvo (ProMine, EU FP7) project area is focused on the Neves Corvo deposit, an active copper mine. The project area is located between the Messejana Fault and the Portuguese/Spanish border which has been selected for the 3D geological and geophysical modelling study, based on high exploration potential of the Neves Corvo area (Oliveira et al. 2006, Relvas et al. 2006, Pereira et al. 2008, Rosa et al. 2008, Matos et al. 2011, Oliveira et al. 2013). In this study existing LNEG and AGC geological, geophysical and geochemistry databases were considered. New surveys were done: i) - A physical volcanology and palynostratigraphic age data study and log of the Cotovio drill-hole core (1,888 m, drilled by AGC). ii) - Interpretation of 280 km of Squid TEM performed by AGC. Based on the TEM data, significant conductors have been identified related with: shallow conductive cover, graphitic shale, black shale and sulphide mineralizations. The most important TEM conductors are related with the Neves Corvo massive sulphides lenses (1-10 Ωm). iii) - Ground and residual gravimetry studies including

  11. Radiological and hydrochemical study of thermal and fresh groundwater samples of northern Euboea and Sperchios areas, Greece: insights into groundwater natural radioactivity and geology.

    Science.gov (United States)

    Kanellopoulos, C; Mitropoulos, P; Argyraki, A

    2018-04-04

    A radiological and hydrochemical study has been conducted on thermal and fresh groundwater samples of northern Euboea Island and eastern central Greece. Both areas are characterized by complex geology and are renowned since antiquity for their hot springs, that are exploited for therapeutic spa purposes until today. The aim of the study was to combine radiological and hydrochemical data in order to achieve a holistic water quality assessment with insights into the geology of the study areas. All samples were characterized with respect to their major and trace ion and element composition, as well as activity concentrations of 222 Rn, 226 Ra, 228 Ra, 228 Th, and 40 K. The samples demonstrated elevated natural radioactivity and U concentrations, especially in some locations of the Kamena Vourla area, reaching 179 Bq/L 222 Rn, 2.2 Bq/L 226 Ra, 2.9 Bq/L 228 Ra, and 17 μg/L U. The estimated circulation depth of thermal groundwater ranges between 250 m in central Greece and 1240 m in north Euboea study area, whereas the calculated water residence times range between 27 and 555 years. Our data suggest the possible presence of an unknown until know U-rich plutonic rock formation in Kamena Vourla area and immiscibility of the fresh and thermal groundwaters in the studied areas.

  12. Popularizing Geological Education among Civil Engineering Students

    Science.gov (United States)

    Chen, Xiang-jun; Zhou, Ying

    2012-01-01

    The sustainable development of an economy and a society cannot be realized without the help of modern geoscience. Engineering geology knowledge is necessary on a civil engineering construction site to ensure the construction work goes smoothly. This paper first discusses the importance of geoscience, especially the study of engineering geology.…

  13. Israel Geological Society, annual meeting 1994

    International Nuclear Information System (INIS)

    Amit, R.; Arkin, Y.; Hirsch, F.

    1994-02-01

    The document is a compilation of papers presented during the annual meeting of Israel Geological Society. The document is related with geological and environmental survey of Israel. It discusses the technology and instruments used to carry out such studies. Main emphasis is given to seismology, geochemical analysis of water, water pollution and geophysical survey of rocks

  14. [Coming-out, support from family of origin and relationship adjustment of lesbian mothers whose children were born in a previous heterosexual relationship: an exploratory study].

    Science.gov (United States)

    Vyncke, Johanna D; Julien, Danielle

    2005-01-01

    Lesbian couples differ from heterosexual couples in that they must develop their relationship within an environment that is generally unsympathetic to homosexuality, a fact that could accentuate the importance of family support. Furthermore, the disclosure of their sexual orientation by lesbian couples could also affect the support given by family members. The present study examines the effect of coming-out and family support on the relationship adjustment of lesbian mothers whose children were born within a heterosexual context. It was expected that family support would mediate the relationship between coming-out and relationship adjustment. Fifty-five lesbian mothers currently in a relationship answered questions about their perception of family support, on their coming-out behaviour and their relationship adjustment. Results revealed a positive relationship between coming-out and family support, and between family support and relationship adjustment, however no association was found between coming-out and relationship adjustment. The mediation model was therefore not confirmed. Finally, the authors discuss the implications of these results.

  15. The geology of the southeastern Baltic Sea: a review

    Science.gov (United States)

    Ūsaitytė, Daiva

    2000-06-01

    The Baltic Sea, particularly its southeastern part, is discussed in the paper. Investigations of regional character as well as specialized studies in the area are reviewed. General historical works are mentioned briefly. Previous surveys since the 1950s are presented by the subject studied. The compilation of geological structure of the SE Baltic Sea bottom and adjacent land of Balticum (Baltic States: Estonia, Latvia, Lithuania) is based on considerable amounts of summarized materials. The crystalline basement, sedimentary cover and Quaternary deposits are characterized in the comprehensive survey of geological structure. From a stratigraphical point of view, geological sequence of the platformal cover is comparatively complete: deposits of all geological systems (from the Archean to Cenozoic) are present in the Baltic Syneclise. Considering geotectonical cycles, the sedimentary cover of the syneclise is subdivided into four structural complexes. The thickness and distribution of Quaternary deposits are closely related to the recent bottom relief of the Baltic Sea that in turn is inherited from the Pre-Quaternary surface. Buried palaeo-valleys are characteristic of the Pre-Quaternary surface in the Baltic region and the Baltic Sea bottom. The Quaternary is characterized by layers of various geneses and by sharp changes of their thicknesses.

  16. Indoor Radon Gas Management For Multi-Site Companies: How To Screen For Potentially High-Risk Sites By Studying The Local Geology

    Science.gov (United States)

    Ruggeri, Rudi; Gigliuto, Andrea; Minnei, Tiziana; Savini, Raffaella

    2008-08-01

    In this article, ENSR presents an evaluation tool for Radon gas monitoring programs that companies with large portfolios of properties will find useful in reducing their efforts and expenditures. The World Health Organization (WHO) considers Radon gas the second cause of lung cancer and the first source of natural radiations affecting the human population. In Italy, Legal Decree No. 230 (0/17/95) is the laws that regulate gas Radon concentrations in work places. Hereunder we present the ENSR approach to executing preliminary geologic studies aimed at planning an instrumental monitoring program for companies.

  17. Application of specific extraction chromatographic methods to the Rb-Sr, Sm-Nd isotope study of geological samples: The Hombreiro-Santa Eulalia Granite (Lugo, NW Spain)

    OpenAIRE

    Santos Zalduegui, J. F.; Pin, C.; Aranguren, A.; Gil Ibarguchi, José Ignacio

    1996-01-01

    The analytical application to geological samples of three new chromatographic resins, TRU-Spec ®, Sr-Spec ® and LN-Spec ®) has been investigated. Seven samples of the Hombreiro massif (Lugo, NW Spain) have been studied, that yield a Rb-Sr age of 298 ±5 Ma (SrQ = 0.7086, MSWD = 7.64) for the magma crystallization. Sm-Nd data results for the same massif give eNd values dose to -2 at 300 Ma. This suggests that the origin of the magma might be related to the partial melting of immature sediments,...

  18. RapidArc, intensity modulated photon and proton techniques for recurrent prostate cancer in previously irradiated patients: a treatment planning comparison study

    International Nuclear Information System (INIS)

    Weber, Damien C; Miralbell, Raymond; Wang, Hui; Cozzi, Luca; Dipasquale, Giovanna; Khan, Haleem G; Ratib, Osman; Rouzaud, Michel; Vees, Hansjoerg; Zaidi, Habib

    2009-01-01

    A study was performed comparing volumetric modulated arcs (RA) and intensity modulation (with photons, IMRT, or protons, IMPT) radiation therapy (RT) for patients with recurrent prostate cancer after RT. Plans for RA, IMRT and IMPT were optimized for 7 patients. Prescribed dose was 56 Gy in 14 fractions. The recurrent gross tumor volume (GTV) was defined on 18 F-fluorocholine PET/CT scans. Plans aimed to cover at least 95% of the planning target volume with a dose > 50.4 Gy. A maximum dose (D Max ) of 61.6 Gy was allowed to 5% of the GTV. For the urethra, D Max was constrained to 37 Gy. Rectal D Median was < 17 Gy. Results were analyzed using Dose-Volume Histogram and conformity index (CI 90 ) parameters. Tumor coverage (GTV and PTV) was improved with RA (V 95% 92.6 ± 7.9 and 83.7 ± 3.3%), when compared to IMRT (V 95% 88.6 ± 10.8 and 77.2 ± 2.2%). The corresponding values for IMPT were intermediate for the GTV (V 95% 88.9 ± 10.5%) and better for the PTV (V 95% 85.6 ± 5.0%). The percentages of rectal and urethral volumes receiving intermediate doses (35 Gy) were significantly decreased with RA (5.1 ± 3.0 and 38.0 ± 25.3%) and IMPT (3.9 ± 2.7 and 25.1 ± 21.1%), when compared to IMRT (9.8 ± 5.3 and 60.7 ± 41.7%). CI 90 was 1.3 ± 0.1 for photons and 1.6 ± 0.2 for protons. Integral Dose was 1.1 ± 0.5 Gy*cm 3 *10 5 for IMPT and about a factor three higher for all photon's techniques. RA and IMPT showed improvements in conformal avoidance relative to fixed beam IMRT for 7 patients with recurrent prostate cancer. IMPT showed further sparing of organs at risk

  19. Global Journal of Geological Sciences: Editorial Policies

    African Journals Online (AJOL)

    Focus and Sco