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Sample records for preventing overturn part

  1. Novel Control Scheme of Power Assisted Wheelchair for Preventing Overturn (Part I)-Adjustment of Assisted Torque and Performance Evaluation From Field Test-

    Science.gov (United States)

    Seki, Hirokazu; Hata, Naoki; Koyasu, Yuichi; Hori, Yoichi

    Aged people and disabled people who have difficulty in walking are increasing. As one of mobility support, significance of power assisted wheelchair which assists driving force using electric motors and spreads their living areas has been enhanced. However, the increased driving force often causes a dangerous overturn of wheelchair. In this paper, control method to prevent power assisted wheelchair from overturning is proposed. It is found the front wheels rising is caused by magnitude and rapid increase of assisted torque. Therefore, feedforward control method to limit the assisted torque by tuning its magnitude or time constant is proposed. In order to emphasize safety and feeling of security, these methods make the front wheels no rise. The effectiveness of the proposed method is verified by the practical experiments and field test based performance evaluation using many trial subjects.

  2. Novel Control Scheme of Power Assisted Wheelchair for Preventing Overturn (Part II)-Variable Assistance Ratio Control Based on Estimation of Center-of-Gravity Angle and Phase Plane-

    Science.gov (United States)

    Hata, Naoki; Seki, Hirokazu; Koyasu, Yuichi; Hori, Yoichi

    Aged people and disabled people who have difficulty in walking are increasing. As one of mobility support, significance of a power assisted wheelchair which assists driving force using electric motors and spreads their living areas has been enhanced. However, the increased driving force often causes a dangerous overturn of wheelchair. This paper proposes a novel control method to prevent power assisted wheelchair from overturning. The man-wheelchair system can be regarded as an inverse pendulum model when the front wheels are rising. The center-of-gravity (COG) angle of the model is the most important information directly-linked to overturn. Behavior of the system can be analyzed using phase plane as shown in this paper. The COG angle cannot be directly measured using a sensor, therefore, COG observer based on its velocity is proposed. On the basis of the analysis on phase plane, a novel control method with variable assistance ratio to prevent a dangerous overturn is proposed. The effectiveness of the proposed method is verified by the practical experiments on the flat ground and uphill slope.

  3. Evaluation of overturning capacity of low level radioactive waste drum during earthquake. Part 2. Investigation of drum weight distribution effect and drum columns interaction by numerical analysis

    International Nuclear Information System (INIS)

    Tochigi, Hitoshi

    2011-01-01

    Numerical analysis case study is carried out for three layered and four layered low level radioactive waste drums by numerical models based on the results of shaking table test. First of all, numerical analysis results about drums displacement due to uplift and sliding on pallets during earthquake are compared with the experimental results and it is shown good agreement in both results. By this analytical model effects of drum weight distribution along height direction and drum columns interaction followed by each other drum's collisions on overturning capacity during earthquake are researched. From numerical analysis results the limit acceleration which is minimum value of input acceleration at storage building floor when three layered or four layered waste drums overturn is researched. It is shown that overturning capacity during earthquake decline when height of gravity center of three layered and four layered drums get large. So it is available to get down height of gravity center by controlling drum weight distribution along height direction. And as effect of drum columns interaction it is indicated that overturning capacity of single column arrangement drums is larger than that of many columns arrangement drums because phase deference between drum columns occur and decrease vibration amplitude by each other collisions. (author)

  4. Active Pacific meridional overturning circulation (PMOC) during the warm Pliocene

    OpenAIRE

    Burls, Natalie J.; Fedorov, Alexey V.; Sigman, Daniel M.; Jaccard, Samuel L.; Tiedemann, Ralf; Haug, Gerald H.

    2017-01-01

    An essential element of modern ocean circulation and climate is the Atlantic meridional overturning circulation (AMOC), which includes deep-water formation in the subarctic North Atlantic. However, a comparable overturning circulation is absent in the Pacific, theworld's largest ocean, where relatively fresh surface waters inhibitNorth Pacific deep convection. We present complementary measurement and modeling evidence that the warm, similar to 400-ppmv (parts per million by volume) CO2 world ...

  5. Counterfeit Parts Prevention Strategies Guide

    Science.gov (United States)

    2014-06-24

    Ford, Flextronics Dale Gordon, Aerojet Rocketdyne Larry Harzstark, The Aerospace Corporation Brian Hughitt, NASA Yehwan Kim, Moog Mark King ...mechanical inputs with electrical outputs, or combinations of each. Examples of electro-mechanical parts are motors , synchros, servos, and some...Hong Kong and sold them to the U.S. Navy, defense contractors and others, marketing some of these products as “military-grade.” In its press release

  6. Active Pacific meridional overturning circulation (PMOC) during the warm Pliocene.

    Science.gov (United States)

    Burls, Natalie J; Fedorov, Alexey V; Sigman, Daniel M; Jaccard, Samuel L; Tiedemann, Ralf; Haug, Gerald H

    2017-09-01

    An essential element of modern ocean circulation and climate is the Atlantic meridional overturning circulation (AMOC), which includes deep-water formation in the subarctic North Atlantic. However, a comparable overturning circulation is absent in the Pacific, the world's largest ocean, where relatively fresh surface waters inhibit North Pacific deep convection. We present complementary measurement and modeling evidence that the warm, ~400-ppmv (parts per million by volume) CO 2 world of the Pliocene supported subarctic North Pacific deep-water formation and a Pacific meridional overturning circulation (PMOC) cell. In Pliocene subarctic North Pacific sediments, we report orbitally paced maxima in calcium carbonate accumulation rate, with accompanying pigment and total organic carbon measurements supporting deep-ocean ventilation-driven preservation as their cause. Together with high accumulation rates of biogenic opal, these findings require vigorous bidirectional communication between surface waters and interior waters down to ~3 km in the western subarctic North Pacific, implying deep convection. Redox-sensitive trace metal data provide further evidence of higher Pliocene deep-ocean ventilation before the 2.73-Ma (million years) transition. This observational analysis is supported by climate modeling results, demonstrating that atmospheric moisture transport changes, in response to the reduced meridional sea surface temperature gradients of the Pliocene, were capable of eroding the halocline, leading to deep-water formation in the western subarctic Pacific and a strong PMOC. This second Northern Hemisphere overturning cell has important implications for heat transport, the ocean/atmosphere cycle of carbon, and potentially the equilibrium response of the Pacific to global warming.

  7. Atlantic Meridional Overturning Circulation slowdown cooled the subtropical ocean.

    Science.gov (United States)

    Cunningham, Stuart A; Roberts, Christopher D; Frajka-Williams, Eleanor; Johns, William E; Hobbs, Will; Palmer, Matthew D; Rayner, Darren; Smeed, David A; McCarthy, Gerard

    2013-12-16

    [1] Observations show that the upper 2 km of the subtropical North Atlantic Ocean cooled throughout 2010 and remained cold until at least December 2011. We show that these cold anomalies are partly driven by anomalous air-sea exchange during the cold winters of 2009/2010 and 2010/2011 and, more surprisingly, by extreme interannual variability in the ocean's northward heat transport at 26.5°N. This cooling driven by the ocean's meridional heat transport affects deeper layers isolated from the atmosphere on annual timescales and water that is entrained into the winter mixed layer thus lowering winter sea surface temperatures. Here we connect, for the first time, variability in the northward heat transport carried by the Atlantic Meridional Overturning Circulation to widespread sustained cooling of the subtropical North Atlantic, challenging the prevailing view that the ocean plays a passive role in the coupled ocean-atmosphere system on monthly-to-seasonal timescales.

  8. Rayleigh-Taylor convective overturn in stellar collapse

    International Nuclear Information System (INIS)

    Bruenn, S.W.; Buchler, J.R.; Livio, M.

    1979-01-01

    Rayleigh--Taylor convective overturn in collapsing stellar cores is modeled with a one-dimensional parametrization. The results of a numerical hydrodynamic study are very encouraging and indicate that such an overturn could well be a dominant feature in the supernova explosion mechanism

  9. Seasonal overturning circulation in the Red Sea: 1. Model validation and summer circulation

    KAUST Repository

    Yao, Fengchao

    2014-04-01

    The overturning circulation in the Red Sea exhibits a distinct seasonally reversing pattern and is studied using high-resolution MIT general circulation model simulations. In the first part of this study, the vertical and horizontal structure of the summer overturning circulation and its dynamical mechanisms are presented from the model results. The seasonal water exchange in the Strait of Bab el Mandeb is successfully simulated, and the structures of the intruding subsurface Gulf of Aden intermediate water are in good agreement with summer observations in 2011. The model results suggest that the summer overturning circulation is driven by the combined effect of the shoaling of the thermocline in the Gulf of Aden resulting from remote winds in the Arabian Sea and an upward surface slope from the Red Sea to the Gulf of Aden set up by local surface winds in the Red Sea. In addition, during late summer two processes associated, respectively, with latitudinally differential heating and increased salinity in the southern Red Sea act together to cause the reversal of the contrast of the vertical density structure and the cessation of the summer overturning circulation. Dynamically, the subsurface northward pressure gradient force is mainly balanced by vertical viscosity resulting from the vertical shear and boundary friction in the Strait of Bab el Mandeb. Unlike some previous studies, the three-layer summer exchange flows in the Strait of Bab el Mandeb do not appear to be hydraulically controlled.

  10. Modelling the Seasonal Overturning Circulation in the Red Sea

    KAUST Repository

    Yao, Fengchao

    2015-04-01

    The overturning circulation in the Red Sea exhibits a distinct seasonally reversing pattern and is studied using 50-year, high-resolution MIT general circulation model simulations. The seasonal water exchange in the Strait of Bab el Mandeb is successfully simulated, and the structures of the intruding subsurface Gulf of Aden intermediate water are in good agreement with summer observations in 2011. The model results suggest that the summer overturning circulation is driven by the combined effect of the shoaling of the thermocline in the Gulf of Aden resulting from remote winds in the Arabian Sea and an upward surface slope from the Red Sea to the Gulf of Aden set up by local surface winds in the Red Sea. For the winter overturning circulation, the climatological model mean results suggest that the surface inflow intensifies in a western boundary current in the southern Red Sea that switches to an eastern boundary current north of 24°N. The overturning is accomplished through a cyclonic recirculation and a cross-basin overturning circulation in the northern Red Sea, with major sinking occurring along a narrow band of width about 20 km along the eastern boundary and weaker upwelling along the western boundary. The northward pressure gradient force, strong vertical mixing, and horizontal mixing near the boundary are the essential dynamical components in the model\\'s winter overturning circulation.

  11. The importance of deep, basinwide measurements in optimized Atlantic Meridional Overturning Circulation observing arrays

    Science.gov (United States)

    McCarthy, G. D.; Menary, M. B.; Mecking, J. V.; Moat, B. I.; Johns, W. E.; Andrews, M. B.; Rayner, D.; Smeed, D. A.

    2017-03-01

    The Atlantic Meridional Overturning Circulation (AMOC) is a key process in the global redistribution of heat. The AMOC is defined as the maximum of the overturning stream function, which typically occurs near 30°N in the North Atlantic. The RAPID mooring array has provided full-depth, basinwide, continuous estimates of this quantity since 2004. Motivated by both the need to deliver near real-time data and optimization of the array to reduce costs, we consider alternative configurations of the mooring array. Results suggest that the variability observed since 2004 could be reproduced by a single tall mooring on the western boundary and a mooring to 1500 m on the eastern boundary. We consider the potential future evolution of the AMOC in two generations of the Hadley Centre climate models and a suite of additional CMIP5 models. The modeling studies show that deep, basinwide measurements are essential to capture correctly the future decline of the AMOC. We conclude that, while a reduced array could be useful for estimates of the AMOC on subseasonal to decadal time scales as part of a near real-time data delivery system, extreme caution must be applied to avoid the potential misinterpretation or absence of a climate time scale AMOC decline that is a key motivation for the maintenance of these observations.Plain Language SummaryThe Atlantic Overturning Circulation is a system of ocean currents that carries heat northwards in the Atlantic. This heat is crucial to maintaining the mild climate of northwest Europe. The Overturning Circulation is predicted to slow in future in response to man-made climate change. The RAPID program is designed to measure the Overturning Circulation using a number of fixed point observations spanning the Atlantic between the Canary Islands and the Bahamas. We look at whether we could reduce the number of these fixed point observations to continue to get accurate estimates of the overturning strength but for less cost. We conclude that

  12. The Emergence of the Pacific Meridional Overturning Circulation (PMOC) Paced by Obliquity Cycles during the Pliocene

    Science.gov (United States)

    Burls, N.; Fedorov, A. V.; Sigman, D. M.; Jaccard, S.; Tiedemann, R.; Haug, G. H.

    2016-12-01

    Deep water formation in northern high latitudes, as part of the Atlantic meridional overturning circulation (AMOC), is a critical element of modern ocean circulation and climate. For the warm Pliocene, roughly 4 to 2.8 million years ago, we present measurements and modeling evidence that deep water formation also occurred in the North Pacific, supporting another overturning cell - the Pacific meridional overturning circulation (PMOC). The evidence includes calcium carbonate accumulation in Pliocene subarctic Pacific sediments rivaling that of the modern North Atlantic, with pigment, total organic carbon, and redox-sensitive trace metal measurements supporting deep ocean ventilation as the driver of the enhanced calcium carbonate preservation. Together with high accumulation rates of biogenic opal, this implies a bi-directional communication between surface waters and the waters overlying the deep seafloor, and hence deep convection. A Pliocene-like climate simulation reproduces this deep water formation, with co-occurring Atlantic and Pacific overturning cells. The PMOC emerges as a result of the less intense hydrological cycle under Pliocene conditions characterized by a reduced meridional SST gradient. This weaker hydrological cycle leads to the erosion of the North Pacific halocline, allowing deep convection. Examining the data in more detail shows that, while the opal accumulation rate was continuously high, maxima in calcium carbonate accumulation rate were sharp and intermittent. Most likely, these maxima occurred during Northern Hemisphere summer insolation maxima when, as supported by the modeling results, mid-latitude SSTs in the Northern Hemisphere were at a maximum and the meridional SST gradient was particularly weak. These findings suggest that the climate system fluctuated between periods of strong and weak PMOC during the Pliocene. Such fluctuations appear to be a crucial part of Pliocene climate variability on orbital timescales.

  13. Late Holocene sea level variability and Atlantic Meridional Overturning Circulation

    Science.gov (United States)

    Cronin, Thomas M.; Farmer, Jesse R.; Marzen, R. E.; Thomas, E.; Varekamp, J.C.

    2014-01-01

    Pre-twentieth century sea level (SL) variability remains poorly understood due to limits of tide gauge records, low temporal resolution of tidal marsh records, and regional anomalies caused by dynamic ocean processes, notably multidecadal changes in Atlantic Meridional Overturning Circulation (AMOC). We examined SL and AMOC variability along the eastern United States over the last 2000 years, using a SL curve constructed from proxy sea surface temperature (SST) records from Chesapeake Bay, and twentieth century SL-sea surface temperature (SST) relations derived from tide gauges and instrumental SST. The SL curve shows multidecadal-scale variability (20–30 years) during the Medieval Climate Anomaly (MCA) and Little Ice Age (LIA), as well as the twentieth century. During these SL oscillations, short-term rates ranged from 2 to 4 mm yr−1, roughly similar to those of the last few decades. These oscillations likely represent internal modes of climate variability related to AMOC variability and originating at high latitudes, although the exact mechanisms remain unclear. Results imply that dynamic ocean changes, in addition to thermosteric, glacio-eustatic, or glacio-isostatic processes are an inherent part of SL variability in coastal regions, even during millennial-scale climate oscillations such as the MCA and LIA and should be factored into efforts that use tide gauges and tidal marsh sediments to understand global sea level rise.

  14. Mixing and diffusion in intermittent overturning turbulence

    Science.gov (United States)

    Redondo, Jose M.; Mahjoub, Otman B.; Gonzalez-Nieto, Pilar L.; Lawry, Andrew

    2014-05-01

    The improvements in experimental methods and high resolution image analysis are nowadays able to detect subtle changes in the structure of the turbulence over a wide range of temporal and spatial scales [1], we compare the scaling shown by different mixing fronts driven by buoyancy that form a Rayleigh-Taylor mixing front. We use PIV and density front tracking in several experimental configurations akin to geophysical overturning [2-7]. We parametrize the role of unstable stratification by means of the Atwood number and compare both the scaling and the multifractal and the maximum local fractal structure functions of the different markers used to visualize the front. Both reactive and passive scalar tracers are used to investigate the mixing structure and the intermittency of the flow. Different initial conditions are compared and the mixing efficiency of the overal turbulent process evaluated [6-7]. An interesting approach, relating the Multi-Fractal dimension spectra, the intermittency and the spectral exponent is to find relationships that may be used to parameterise the sub-grid turbulence in terms of generalized diffusivities [4 ] that take into account the topology and the self-similarity of the Mixing RT and RM flows. As an example, a relationship between the diffusivity, the exponent β, the intermittency μ, and D(i), may be found for the volume fraction or the concentration, at the same time other locally measured parameters such as the enstrophy or the gradient alignment as well as their multi-fractal structures may turn out to be physically relevant indicators of the local turbulence and the mixing. Several methods of deriving local eddy diffusivity and local entrainment should give more realistic estimates of the spatial/temporal non-homogeneities (and intermittencies in the Kolmogorov 62 sense obtained as spatial correlations of the turbulent dissipation, or from structure functions) and these values may be used to parameterise turbulence at a variety

  15. Impact of interocean exchange on the Atlantic overturning circulation

    NARCIS (Netherlands)

    Weijer, W.

    2000-01-01

    The awareness that human activity could change climate has greatly raised public and scientific interest in climate. One issue of present-day climate research is the stability of the thermohaline circulation. This overturning circulation, popularly known as the `conveyor belt', redistributes

  16. An integral part of an integrated preventive maintenance program

    International Nuclear Information System (INIS)

    Ferguson, B.J.

    1992-01-01

    This paper outlines the evolution of the Integrated Preventive Maintenance Program from the Reliability Centered Maintenance pilot program at Bruce Nuclear Generating Station (NGS) 'A.' The Integrated Preventive Maintenance Program provides the means for taking control of the Bruce NGS 'A' Preventive Maintenance Program. In addition, the development of the Bruce NGS 'A' Air-Operated Valve Preventive Maintenance is reviewed

  17. Seasonal overturning circulation in the Red Sea: 2. Winter circulation

    KAUST Repository

    Yao, Fengchao

    2014-04-01

    The shallow winter overturning circulation in the Red Sea is studied using a 50 year high-resolution MITgcm (MIT general circulation model) simulation with realistic atmospheric forcing. The overturning circulation for a typical year, represented by 1980, and the climatological mean are analyzed using model output to delineate the three-dimensional structure and to investigate the underlying dynamical mechanisms. The horizontal model circulation in the winter of 1980 is dominated by energetic eddies. The climatological model mean results suggest that the surface inflow intensifies in a western boundary current in the southern Red Sea that switches to an eastern boundary current north of 24N. The overturning is accomplished through a cyclonic recirculation and a cross-basin overturning circulation in the northern Red Sea, with major sinking occurring along a narrow band of width about 20 km along the eastern boundary and weaker upwelling along the western boundary. The northward pressure gradient force, strong vertical mixing, and horizontal mixing near the boundary are the essential dynamical components in the model\\'s winter overturning circulation. The simulated water exchange is not hydraulically controlled in the Strait of Bab el Mandeb; instead, the exchange is limited by bottom and lateral boundary friction and, to a lesser extent, by interfacial friction due to the vertical viscosity at the interface between the inflow and the outflow. Key Points Sinking occurs in a narrow boundary layer along the eastern boundary Surface western boundary current switches into an eastern boundary current Water exchange in the Strait of Bab el Mandeb is not hydraulically controlled © 2014. American Geophysical Union. All Rights Reserved.

  18. Atlantic overturning responses to Late Pleistocene climate forcings.

    Science.gov (United States)

    Lisiecki, Lorraine E; Raymo, Maureen E; Curry, William B

    2008-11-06

    The factors driving glacial changes in ocean overturning circulation are not well understood. On the basis of a comparison of 20 climate variables over the past four glacial cycles, the SPECMAP project proposed that summer insolation at high northern latitudes (that is, Milankovitch forcing) drives the same sequence of ocean circulation and other climate responses over 100-kyr eccentricity cycles, 41-kyr obliquity cycles and 23-kyr precession cycles. SPECMAP analysed the circulation response at only a few sites in the Atlantic Ocean, however, and the phase of circulation response has been shown to vary by site and orbital band. Here we test the SPECMAP hypothesis by measuring the phase of orbital responses in benthic delta(13)C (a proxy indicator of ocean nutrient content) at 24 sites throughout the Atlantic over the past 425 kyr. On the basis of delta(13)C responses at 3,000-4,010 m water depth, we find that maxima in Milankovitch forcing are associated with greater mid-depth overturning in the obliquity band but less overturning in the precession band. This suggests that Atlantic overturning is strongly sensitive to factors beyond ice volume and summer insolation at high northern latitudes. A better understanding of these processes could lead to improvements in model estimates of overturning rates, which range from a 40 per cent increase to a 40 per cent decrease at the Last Glacial Maximum and a 10-50 per cent decrease over the next 140 yr in response to projected increases in atmospheric CO(2) (ref. 4).

  19. Pulling the Meridional Overturning Circulation From the South DESC0005100

    Energy Technology Data Exchange (ETDEWEB)

    Cessi, Paola [Univ. of California, San Diego, CA (United States); Wolfe, Christopher L. [Scripps Inst. of Oceanography, San Diego, CA (United States)

    2015-11-25

    This project concerned the Atlantic Meridional Overturning Circulation (AMOC), its stability, variability and sensitivity to atmospheric forcing, both mechanical (wind-stress) and thermodynamical (heat and freshwater surface fluxes). The focus of the study is the interhemispheric cell in the largely adiabatic regime, where the flow is characterized by a descending branch in the high latitudes of the North Atlantic and the upwelling branch in the Antarctic Circumpolar Current (ACC) region of the Southern Ocean. These two end points are connected by shared isopycnals along which the flow takes place. The approach is to systematically study the amplitude and frequency of the AMOC’s response to localized buoyancy with an ocean-only model in both coarse and high-resolution configurations, analyzed with innovative diagnostics, focused on the “residual overturning circulation” (ROC), which is the proper measure of the transport of heat and other tracers.

  20. Contribution of topographically generated submesoscale turbulence to Southern Ocean overturning

    Science.gov (United States)

    Ruan, Xiaozhou; Thompson, Andrew F.; Flexas, Mar M.; Sprintall, Janet

    2017-11-01

    The ocean's global overturning circulation regulates the transport and storage of heat, carbon and nutrients. Upwelling across the Southern Ocean's Antarctic Circumpolar Current and into the mixed layer, coupled to water mass modification by surface buoyancy forcing, has been highlighted as a key process in the closure of the overturning circulation. Here, using twelve high-resolution hydrographic sections in southern Drake Passage, collected with autonomous ocean gliders, we show that Circumpolar Deep Water originating from the North Atlantic, known as Lower Circumpolar Deep Water, intersects sloping topography in narrow and strong boundary currents. Observations of strong lateral buoyancy gradients, enhanced bottom turbulence, thick bottom mixed layers and modified water masses are consistent with growing evidence that topographically generated submesoscale flows over continental slopes enhance near-bottom mixing, and that cross-density upwelling occurs preferentially over sloping topography. Interactions between narrow frontal currents and topography occur elsewhere along the path of the Antarctic Circumpolar Current, which leads us to propose that such interactions contribute significantly to the closure of the overturning in the Southern Ocean.

  1. Preventing Suicide in Prisons, Part I Recommendations fromthe International Association for Suicide Prevention Task Force on Suicide in Prisons

    NARCIS (Netherlands)

    Konrad, N.; Daigle, M.S.; Daniel, A.E.; Dear, G.E.; Frottier, P.; Hayes, L.M.; Kerkhof, A.J.F.M.; Liebling, A.; Sarchiapone, M.

    2007-01-01

    In 2000 the Department of Mental Health of the World Health Organization (WHO) published a guide named Preventing Suicide. A Resource for Prison Officers as part of the WHO worldwide initiative for the prevention of suicide. In 2007 there are new epidemiological data on prison suicide, a more

  2. Reducing Youth Gun Violence. Part One--An Overview [and] Part Two--Prevention and Intervention Programs.

    Science.gov (United States)

    McEvoy, Alan, Ed.

    1996-01-01

    This document contains two issues of a journal on reducing youth gun violence, reprinted from a report by the U.S. Department of Justice. The first issue, part one, provides an overview of programs and initiatives. The second issue, part two, describes prevention and intervention programs. To reduce violence and build healthy communities requires…

  3. Wind-driven variations in an overturning circulation

    Science.gov (United States)

    Bringedal, Carina; Eldevik, Tor; Spall, Michael

    2017-04-01

    The Atlantic overturning circulation and poleward heat transport is balanced by northern heat loss to the atmosphere and corresponding water mass transformation. The structure of this circulation and transformation is particularly manifested - and observed - at the Greenland-Scotland ridge. There is however a rich variability in the exchanges across the ridge on seasonal and yearly time scales. This variability has been almost perfectly captured in atmospherically forced ocean GCMs (e.g. Olsen et al 2008, Sandø et al 2012), suggesting that on shorter time scales the variability of the exchanges are connected to sea level pressure and corresponding wind stress forcing. Focusing on seasonal and yearly time scales, we accordingly propose that the connection between the exchanges of overturning waters across the Greenland-Scotland ridge and the sea level pressure must be direct and simple, and we use idealized simulations to support this hypothesis. The mechanisms underlying the connection are formulated through conceptual models. Although the models and simulations are simplified with respect to bathymetry and hydrography, they can reproduce the main features of the overturning circulation in the Nordic seas. In the observations, the variable exchanges can largely be related to sea level pressure variations and large scale wind patterns, and the idealized simulations and accompanying conceptual models show how these impacts can manifest via coastal downwelling and gyre circulation. S. M. Olsen, B. Hansen, D. Quadfasel and S. Østerhus, Observed and modelled stability of overflow across the Greenland-Scotland ridge, Nature 455, (2008) A. B. Sandø, J. E. Ø. Nilsen, T. Eldevik and M. Bentsen, Mechanisms for variable North Atlantic-Nordic seas exchanges, Journal of Geophysical Research 117, (2012)

  4. Pre-eclampsia part 2: prediction, prevention and management.

    Science.gov (United States)

    Chaiworapongsa, Tinnakorn; Chaemsaithong, Piya; Korzeniewski, Steven J; Yeo, Lami; Romero, Roberto

    2014-09-01

    An antiangiogenic state might constitute a terminal pathway for the multiple aetiologies of pre-eclampsia, especially those resulting from placental abnormalities. The levels of angiogenic and antiangiogenic proteins in maternal blood change prior to a diagnosis of pre-eclampsia, correlate with disease severity and have prognostic value in identifying women who will develop maternal and/or perinatal complications. Potential interventions exist to ameliorate the imbalance of angiogenesis and, hence, might provide opportunities to improve maternal and/or perinatal outcomes in pre-eclampsia. Current strategies for managing pre-eclampsia consist of controlling hypertension, preventing seizures and timely delivery of the fetus. Prediction of pre-eclampsia in the first trimester is of great interest, as early administration of aspirin might reduce the risk of pre-eclampsia, albeit modestly. Combinations of biomarkers typically predict pre-eclampsia better than single biomarkers; however, the encouraging initial results of biomarker studies require external validation in other populations before they can be used to facilitate intervention in patients identified as at increased risk. Angiogenic and antiangiogenic factors might also be useful in triage of symptomatic patients with suspected pre-eclampsia, differentiating pre-eclampsia from exacerbations of pre-existing medical conditions and performing risk assessment in asymptomatic women. This Review article discusses the performance of predictive and prognostic biomarkers for pre-eclampsia, current strategies for preventing and managing the condition and its long-term consequences.

  5. Preventing Suicide in Prisons, Part II International Comparisons of Suicide Prevention Services in Correctional Facilities

    NARCIS (Netherlands)

    Diagle, M.S.; Daniel, A.E.; Dear, G.E.; Frottier, P.; Hayes, H.M.; Kerkhof, A.J.F.M.; Konrad, N.; Liebling, A.; Sarchiapone, M.

    2007-01-01

    The International Association for Suicide Prevention created a Task Force on Suicide in Prisons to better disseminate the information in this domain. One of its objectives was to summarize suicide-prevention activities in the prison systems. This study of the Task Force uncovered many differences

  6. Strategy to prevent surface deflections for automotive sheet metal parts

    Science.gov (United States)

    Weinschenk, A.; Volk, W.

    2017-09-01

    Surface deflections are undesirable in automotive outer panels because they disturb their visual appearance. As a consequence, the geometry of the deep drawing tool is manually adjusted during tryout until the produced parts do not display any surface deflections. The aim of this paper is to reduce this time-consuming and cost-intensive tryout by slightly changing the geometry of the tool in an early state of the product development process to lower the risk of surface deflections. Therefore, this paper shows the influence of geometrical parameters of the deep drawing tool on the occurrence of surface deflections. A multiple curved outer panel with a door handle depression is chosen for the investigation. Typically, so-called “teddy bear ears” occur around the depression. The sheet metal material AA6016 with a sheet thickness of 1.0 mm is used. Numerical simulations of the draw operation and springback are performed in AutoForm. An analysis of the curvature before and after springback is used to detect surface deflections. The influence of the stresses and curvatures on the appearance of surface deflections is analyzed. For the experimental validation, stoning is used to detect surface deflections on a physical part. A very good agreement between the numerical and experimental results was obtained. The results show that the existence of surface deflections strongly depends on the initial curvature of the part and the appearance depends on the distribution of minor stresses. It is possible to reduce the risk of surface deflections during the design phase by changing the geometry.

  7. There is no real evidence for a diminishing trend of the Atlantic meridional overturning circulation

    Directory of Open Access Journals (Sweden)

    A. Parker

    2016-01-01

    Full Text Available The Atlantic Meridional Overturning Circulation (AMOC is part of the great ocean “conveyor belt” that circulates heat around the globe. Since the early 2000s, ocean sensors have started to monitor the AMOC, but the measurements are still far from accurate and the time window does not permit the separation of short term variability from a longer term trend. Other works have claimed that global warming is slowing down the AMOC, based on models and proxies of temperatures. Some other observations demonstrate a stable circulation of the oceans. By using tide gauge data complementing recent satellite and ocean sensor observations, the stability of the AMOC is shown to go back to 1860. It is concluded that no available information has the due accuracy and time coverage to show a clear trend outside the inter-annual and multi-decadal variability in the direction of increasing or decreasing strength over the last decades.

  8. On the stability of the Atlantic meridional overturning circulation

    Science.gov (United States)

    Hofmann, Matthias; Rahmstorf, Stefan

    2009-01-01

    One of the most important large-scale ocean current systems for Earth's climate is the Atlantic meridional overturning circulation (AMOC). Here we review its stability properties and present new model simulations to study the AMOC's hysteresis response to freshwater perturbations. We employ seven different versions of an Ocean General Circulation Model by using a highly accurate tracer advection scheme, which minimizes the problem of numerical diffusion. We find that a characteristic freshwater hysteresis also exists in the predominantly wind-driven, low-diffusion limit of the AMOC. However, the shape of the hysteresis changes, indicating that a convective instability rather than the advective Stommel feedback plays a dominant role. We show that model errors in the mean climate can make the hysteresis disappear, and we investigate how model innovations over the past two decades, like new parameterizations and mixing schemes, affect the AMOC stability. Finally, we discuss evidence that current climate models systematically overestimate the stability of the AMOC. PMID:19897722

  9. 33 CFR Appendix A to Part 274 - Preventive Safety Measures in Handling of Pesticides

    Science.gov (United States)

    2010-07-01

    ... Handling of Pesticides A Appendix A to Part 274 Navigation and Navigable Waters CORPS OF ENGINEERS... Appendix A to Part 274—Preventive Safety Measures in Handling of Pesticides 1. Follow the label on each... permitted while pesticides are being handled. 4. All pesticides must be handled in well-vetilated areas to...

  10. A multimodel comparison of centennial Atlantic meridional overturning circulation variability

    Energy Technology Data Exchange (ETDEWEB)

    Menary, Matthew B.; Vellinga, Michael; Palmer, Matthew D. [Met Office Hadley Centre, Exeter, Devon (United Kingdom); Park, Wonsun; Latif, Mojib [IFM-GEOMAR, Leibniz-Institut fuer Meereswissenschaften, Kiel (Germany); Lohmann, Katja; Jungclaus, Johann H. [Max Planck Inst Meteorol, Hamburg (Germany)

    2012-06-15

    A mechanism contributing to centennial variability of the Atlantic Meridional Overturning Circulation (AMOC) is tested with multi-millennial control simulations of several coupled general circulation models (CGCMs). These are a substantially extended integration of the 3rd Hadley Centre Coupled Climate Model (HadCM3), the Kiel Climate Model (KCM), and the Max Plank Institute Earth System Model (MPI-ESM). Significant AMOC variability on time scales of around 100 years is simulated in these models. The centennial mechanism links changes in the strength of the AMOC with oceanic salinities and surface temperatures, and atmospheric phenomena such as the Intertropical Convergence Zone (ITCZ). 2 of the 3 models reproduce all aspects of the mechanism, with the third (MPI-ESM) reproducing most of them. A comparison with a high resolution paleo-proxy for Sea Surface Temperatures (SSTs) north of Iceland over the last 4,000 years, also linked to the ITCZ, suggests that elements of this mechanism may also be detectable in the real world. (orig.)

  11. Public-Private Partnerships in Chronic Disease Prevention-Part 3

    Centers for Disease Control (CDC) Podcasts

    2009-04-06

    This podcast is the third of a seven part series discussing public health partnerships with the private sector. In this segment, CDC's Elizabeth Majestic and University of North Carolina's Gene Matthews talk about how building credibility on preparedness issues can help develop support for initiatives around chronic disease prevention.  Created: 4/6/2009 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 4/6/2009.

  12. On the Linkage between Labrador Sea Water Volume and Overturning Circulation in the Labrador Sea

    Science.gov (United States)

    Li, Feili; Lozier, Susan

    2017-04-01

    The linkage between the volume of newly formed Labrador Sea Water (LSW) and overturning in the Labrador Sea is investigated using output from an eddy-resolving ocean general circulation model (OGCM) in order to understand the mechanisms driving overturning variability. Overturning transport is estimated in density space across the western leg (from Labrador to Greenland) of the OSNAP (Overturning in the Subpolar North Atlantic Program) array. We estimate the LSW volume northwest of the OSNAP section in order to understand the impact of local LSW formation on transport across the section. As expected, on interannual timescales, a larger LSW volume in the Labrador Sea, due to intensified atmospheric cooling, correlates with stronger overturning (r= 0.61) and an enhanced export of LSW (r= -0.70). Our results also reveal the inadequacy of using indirect measurements for approximating both the strength of convection and of overturning in the Labrador Sea. We demonstrate the desirability of robust estimates derived from direct monitoring, i.e., from the Argo and OSNAP measurements in the region.

  13. Chores at Times of Fatal or Serious Injuries Associated with Tractor Overturns with and without Rollover Protection

    Directory of Open Access Journals (Sweden)

    Henry P. Cole

    2016-09-01

    Full Text Available This study describes chores when farmers were either fatally or seriously injured and required emergency medical treatment as a result of overturns of tractors with or without rollover protective structures (ROPS. Data from the 2002 Kentucky Farm Tractor Overturn Survey were used for this study. The data were collected by a telephone survey of a population-based random sample of 6063 (7.98% of Kentucky’s 76,017 farm operators as listed in the Kentucky Agricultural Statistics Service database. Of farm operators interviewed, 551 (9.1% reported 603 overturns and 5512 (90.9% reported no overturns in the history of their farm, covering a period from 1925 to February 2002. Only the latest overturn was considered to improve recall accuracy. In addition, since the 1925 to 1959 time period had only 49 (8.1% of the overturns reported, (14 farmers did not provide the year of most recent overturn; only data from the 1960 to 2002 period (approximately 41 years were used. After making these adjustments, incidents evaluated included 25 cases (one fatal and four serious nonfatal injuries that involved ROPS-equipped tractor overturns and 88 cases (24 fatal and 64 serious nonfatal injuries that involved non-ROPS tractor overturns. Chores at highest risk for tractor overturns were identified for which educational and ROPS retrofit interventions could be emphasized. The highest frequency of overturn-related fatalities and nonfatal injuries were associated with hay harvesting, rotary mowing, and on-farm travel chores. These three chores represented 68.2% of fatal events and 50.0% of permanent and 56.6% of temporary disability overturn incidents. Tragically, in countries such as India and China with emerging mechanization, a large majority of tractors are produced without ROPS that can be expected to result in the same overturn-related epidemic of deaths experienced in highly mechanized countries, despite evidence of the protection provided by ROPS.

  14. Observed decline of the Atlantic Meridional Overturning circulation 2004 to 2012

    Science.gov (United States)

    Cunningham, Stuart; Smeed, David; Johns, William; Meinen, Chris; Rayner, Darren; Moat, Ben; Duchez, Aurelie; Bryden, Harry; Baringer Molly, O.; McCarthy, Gerard

    2014-05-01

    The Atlantic Meridional Overturning Circulation (AMOC) has been observed continuously at 26° N since April 2004. The AMOC and its component parts are monitored by combining a transatlantic array of moored instruments with submarine-cable based measurements of the Gulf Stream and satellite derived Ekman transport. The time series has recently been extended to October 2012 and the results show a downward trend since 2004. From April~2008 to March 2012 the AMOC was an average of 2.7 Sv weaker than in the first four years of observation (95% confidence that the reduction is 0.3 Sv or more). Ekman transport reduced by about 0.2 Sv and the Gulf Stream by 0.5 Sv but most of the change (2.0 Sv) is due to the mid-ocean geostrophic flow. The change of the mid-ocean geostrophic flow represents a strengthening of the subtropical gyre above the thermocline. The increased southward flow of warm waters is balanced by a decrease in the southward flow of Lower North Atlantic Deep Water below 3000 m. The transport of Lower North Atlantic Deep Water slowed by 7% per year (95% confidence that the rate of slowing is greater than 2.5% per year).

  15. River runoff influences on the Central Mediterranean overturning circulation

    Science.gov (United States)

    Verri, Giorgia; Pinardi, N.; Oddo, P.; Ciliberti, S. A.; Coppini, G.

    2018-03-01

    The role of riverine freshwater inflow on the Central Mediterranean Overturning Circulation (CMOC) was studied using a high-resolution ocean model with a complete distribution of rivers in the Adriatic and Ionian catchment areas. The impact of river runoff on the Adriatic and Ionian Sea basins was assessed by a twin experiment, with and without runoff, from 1999 to 2012. This study tries to show the connection between the Adriatic as a marginal sea containing the downwelling branch of the anti-estuarine CMOC and the large runoff occurring there. It is found that the multiannual CMOC is a persistent anti-estuarine structure with secondary estuarine cells that strengthen in years of large realistic river runoff. The CMOC is demonstrated to be controlled by wind forcing at least as much as by buoyancy fluxes. It is found that river runoff affects the CMOC strength, enhancing the amplitude of the secondary estuarine cells and reducing the intensity of the dominant anti-estuarine cell. A large river runoff can produce a positive buoyancy flux without switching off the antiestuarine CMOC cell, but a particularly low heat flux and wind work with normal river runoff can reverse it. Overall by comparing experiments with, without and with unrealistically augmented runoff we demonstrate that rivers affect the CMOC strength but they can never represent its dominant forcing mechanism and the potential role of river runoff has to be considered jointly with wind work and heat flux, as they largely contribute to the energy budget of the basin. Looking at the downwelling branch of the CMOC in the Adriatic basin, rivers are demonstrated to locally reduce the volume of Adriatic dense water formed in the Southern Adriatic Sea as a result of increased water stratification. The spreading of the Adriatic dense water into the Ionian abyss is affected as well: dense waters overflowing the Otranto Strait are less dense in a realistic runoff regime, with respect to no runoff experiment, and

  16. Atlantic Meridional Overturning Circulation response to idealized external forcing

    Energy Technology Data Exchange (ETDEWEB)

    Park, W.; Latif, M. [Leibniz-Institut fuer Meereswissenschaften an der Universitaet Kiel, Kiel (Germany)

    2012-10-15

    The response of the Atlantic Meridional Overturning Circulation (AMOC) to idealized external (solar) forcing is studied in terms of the internal (unforced) AMOC modes with the Kiel Climate Model (KCM), a coupled atmosphere-ocean-sea ice general circulation model. The statistical investigation of KCM's internal AMOC variability obtained from a multi-millennial control run yields three distinct modes: a multi-decadal mode with a period of about 60 years, a quasi-centennial mode with a period of about 100 years and a multi-centennial mode with a period of about 300-400 years. Most variance is explained by the multi-centennial mode, and the least by the quasi-centennial mode. The solar constant varies sinusoidally with two different periods (100 and 60 years) in forced runs with KCM. The AMOC response to the external forcing is rather complex and nonlinear. It involves strong changes in the frequency structure of the variability. While the control run depicts multi-timescale behavior, the AMOC variability in the experiment with 100 year forcing period is channeled into a relatively narrow band centered near the forcing period. It is the quasi-centennial AMOC mode with a period of just under 100 years which is excited, although it is heavily damped in the control run. Thus, the quasi-centennial mode retains its period which does not correspond exactly to the forcing period. Surprisingly, the quasi-centennial mode is also most strongly excited when the forcing period is set to 60 years, the period of the multi-decadal mode which is rather prominent in the control run. It is largely the spatial structure of the forcing rather than its period that determines which of the three internal AMOC modes is excited. The results suggest that we need to understand the full modal structure of the internal AMOC variability in order to understand the circulation's response to external forcing. This could be a challenge for climate models: we cannot necessarily expect that the

  17. Understanding variability of the Southern Ocean overturning circulation in CORE-II models

    Science.gov (United States)

    Downes, S. M.; Spence, P.; Hogg, A. M.

    2018-03-01

    The current generation of climate models exhibit a large spread in the steady-state and projected Southern Ocean upper and lower overturning circulation, with mechanisms for deep ocean variability remaining less well understood. Here, common Southern Ocean metrics in twelve models from the Coordinated Ocean-ice Reference Experiment Phase II (CORE-II) are assessed over a 60 year period. Specifically, stratification, surface buoyancy fluxes, and eddies are linked to the magnitude of the strengthening trend in the upper overturning circulation, and a decreasing trend in the lower overturning circulation across the CORE-II models. The models evolve similarly in the upper 1 km and the deep ocean, with an almost equivalent poleward intensification trend in the Southern Hemisphere westerly winds. However, the models differ substantially in their eddy parameterisation and surface buoyancy fluxes. In general, models with a larger heat-driven water mass transformation where deep waters upwell at the surface ( ∼ 55°S) transport warmer waters into intermediate depths, thus weakening the stratification in the upper 2 km. Models with a weak eddy induced overturning and a warm bias in the intermediate waters are more likely to exhibit larger increases in the upper overturning circulation, and more significant weakening of the lower overturning circulation. We find the opposite holds for a cool model bias in intermediate depths, combined with a more complex 3D eddy parameterisation that acts to reduce isopycnal slope. In summary, the Southern Ocean overturning circulation decadal trends in the coarse resolution CORE-II models are governed by biases in surface buoyancy fluxes and the ocean density field, and the configuration of the eddy parameterisation.

  18. The Investigation of EM Scattering from the Time-Varying Overturning Wave Crest Model by the IEM

    Directory of Open Access Journals (Sweden)

    Xiao Meng

    2016-01-01

    Full Text Available Investigation of the electromagnetic (EM scattering of time-varying overturning wave crests is a worthwhile endeavor. Overturning wave crest is one of the reasons of sea spike generation, which increases the probability of false radar alarms and reduces the performance of multitarget detection in the environment. A three-dimensional (3D time-varying overturning wave crest model is presented in this paper; this 3D model is an improvement of the traditional two-dimensional (2D time-varying overturning wave crest model. The integral equation method (IEM was employed to investigate backward scattering radar cross sections (RCS at various incident angles of the 3D overturning wave crest model. The super phenomenon, where the intensity of horizontal polarization scattering is greater than that of vertical polarization scattering, is an important feature of sea spikes. Simulation results demonstrate that super phenomena may occur in some time samples as variations in the overturning wave crest.

  19. Public-Private Partnerships in Chronic Disease Prevention-Part 6

    Centers for Disease Control (CDC) Podcasts

    2009-04-06

    This podcast is the sixth of a seven part series discussing public health partnerships with the private sector. In this segment, CDC's Elizabeth Majestic and Georgia State University's Michael Eriksen discuss whether the tobacco industry has forfeited its opportunity to participate in traditional public-private partnerships.  Created: 4/6/2009 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 4/6/2009.

  20. Public-Private Partnerships in Chronic Disease Prevention-Part 7

    Centers for Disease Control (CDC) Podcasts

    2009-04-06

    This podcast is the last installment of a seven part series discussing public health partnerships with the private sector. In this segment, CDC's Elizabeth Majestic and Georgia State University's Michael Eriksen discuss how some lessons learned in the tobacco control experience might be relevant for the obesity epidemic.  Created: 4/6/2009 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 4/6/2009.

  1. Public-Private Partnerships in Chronic Disease Prevention-Part 4

    Centers for Disease Control (CDC) Podcasts

    2009-04-06

    This podcast is the fourth of a seven part series discussing public health partnerships with the private sector. In this segment, CDC's Elizabeth Majestic and University of North Carolina's Gene Matthews talk about strategies that should serve as the cornerstone for partnership development.  Created: 4/6/2009 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 4/6/2009.

  2. Public-Private Partnerships in Chronic Disease Prevention-Part 1

    Centers for Disease Control (CDC) Podcasts

    2009-04-06

    This podcast is the first of a seven part series discussing public health partnerships with the private sector. In this segment, CDC's Elizabeth Majestic and University of North Carolina's Gene Matthews talk about the history of public health partnerships with the for profit sector.  Created: 4/6/2009 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 4/6/2009.

  3. Public-Private Partnerships in Chronic Disease Prevention-Part 5

    Centers for Disease Control (CDC) Podcasts

    2009-04-06

    This podcast is the fifth of a seven part series discussing public health partnerships with the private sector. In this segment, CDC's Elizabeth Majestic and University of North Carolina's Gene Matthews talk about how the economic downturn will increase the demands on public heath.  Created: 4/6/2009 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 4/6/2009.

  4. Public-Private Partnerships in Chronic Disease Prevention-Part 2

    Centers for Disease Control (CDC) Podcasts

    2009-04-06

    This podcast is the second of a seven part series discussing public health partnerships with the private sector. In this segment, CDC's Elizabeth Majestic and University of North Carolina's Gene Matthews talk about sharing resources and forming relationships that address chronic diseases, as well as urgent health threats, such as terrorism.  Created: 4/6/2009 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 4/6/2009.

  5. Surface changes in the North Atlantic meridional overturning circulation during the last millennium

    DEFF Research Database (Denmark)

    Wanamaker, Jr., Alan D.; Butler, Paul G.; Scourse, James D.

    2012-01-01

    the past 1,350 years, to reconstruct changes in surface ocean circulation and climate. The water mass tracer data presented here from the North Icelandic shelf, combined with previously published data from the Arctic and subtropical Atlantic, show that surface Atlantic meridional overturning circulation......Despite numerous investigations, the dynamical origins of the Medieval Climate Anomaly and the Little Ice Age remain uncertain. A major unresolved issue relating to internal climate dynamics is the mode and tempo of Atlantic meridional overturning circulation variability, and the significance...... of decadal-to-centennial scale changes in Atlantic meridional overturning circulation strength in regulating the climate of the last millennium. Here we use the time-constrained high-resolution local radiocarbon reservoir age offset derived from an absolutely dated annually resolved shell chronology spanning...

  6. Surface changes in the North Atlantic meridional overturning circulation during the last millennium

    Science.gov (United States)

    Wanamaker, Alan D.; Butler, Paul G.; Scourse, James D.; Heinemeier, Jan; Eiríksson, Jón; Knudsen, Karen Luise; Richardson, Christopher A.

    2012-01-01

    Despite numerous investigations, the dynamical origins of the Medieval Climate Anomaly and the Little Ice Age remain uncertain. A major unresolved issue relating to internal climate dynamics is the mode and tempo of Atlantic meridional overturning circulation variability, and the significance of decadal-to-centennial scale changes in Atlantic meridional overturning circulation strength in regulating the climate of the last millennium. Here we use the time-constrained high-resolution local radiocarbon reservoir age offset derived from an absolutely dated annually resolved shell chronology spanning the past 1,350 years, to reconstruct changes in surface ocean circulation and climate. The water mass tracer data presented here from the North Icelandic shelf, combined with previously published data from the Arctic and subtropical Atlantic, show that surface Atlantic meridional overturning circulation dynamics likely amplified the relatively warm conditions during the Medieval Climate Anomaly and the relatively cool conditions during the Little Ice Age within the North Atlantic sector. PMID:22692542

  7. Warrior Model for Human Performance and Injury Prevention: Eagle Tactical Athlete Program (ETAP) Part I.

    Science.gov (United States)

    Sell, Timothy C; Abt, John P; Crawford, Kim; Lovalekar, Mita; Nagai, Takashi; Deluzio, Jennifer B; Smalley, Brain W; McGrail, Mark A; Rowe, Russell S; Cardin, Sylvain; Lephart, Scott M

    2010-01-01

    Physical training for United States military personnel requires a combination of injury prevention and performance optimization to counter unintentional musculoskeletal injuries and maximize warrior capabilities. Determining the most effective activities and tasks to meet these goals requires a systematic, research-based approach that is population specific based on the tasks and demands of the warrior. We have modified the traditional approach to injury prevention to implement a comprehensive injury prevention and performance optimization research program with the 101st Airborne Division (Air Assault) at Ft. Campbell, KY. This is Part I of two papers that presents the research conducted during the first three steps of the program and includes Injury Surveillance, Task and Demand Analysis, and Predictors of Injury and Optimal Performance. Injury surveillance based on a self-report of injuries was collected on all Soldiers participating in the study. Field-based analyses of the tasks and demands of Soldiers performing typical tasks of 101st Soldiers were performed to develop 101st-specific laboratory testing and to assist with the design of the intervention (Eagle Tactical Athlete Program (ETAP)). Laboratory testing of musculoskeletal, biomechanical, physiological, and nutritional characteristics was performed on Soldiers and benchmarked to triathletes to determine predictors of injury and optimal performance and to assist with the design of ETAP. Injury surveillance demonstrated that Soldiers of the 101st are at risk for a wide range of preventable unintentional musculoskeletal injuries during physical training, tactical training, and recreational/sports activities. The field-based analyses provided quantitative data and qualitative information essential to guiding 101st specific laboratory testing and intervention design. Overall the laboratory testing revealed that Soldiers of the 101st would benefit from targeted physical training to meet the specific demands of

  8. Stability of the Atlantic overturning circulation: competition between Bering Strait freshwater flux and Agulhas heat and salt sources

    NARCIS (Netherlands)

    Weijer, W.; Ruijter, W.P.M. de; Dijkstra, H.A.

    2000-01-01

    In this study we examine the role that is played by interocean fluxes of buoyancy in stabilizing the present-day overturning circulation of the Atlantic Ocean. A 2D model of the Atlantic overturning circulation is used, in which the interocean fluxes of heat and salt (via the Bering Strait, the

  9. Meridional overturning circulation: stability and ocean feedbacks in a box model

    NARCIS (Netherlands)

    Cimatoribus, A.A.; Drijfhout, S.S.; Dijkstra, H.A.|info:eu-repo/dai/nl/073504467

    2014-01-01

    A box model of the inter-hemispheric Atlantic meridional overturning circulation is developed, including a variable pycnocline depth for the tropical and subtropical regions. The circulation is forced by winds over a periodic channel in the south and by freshwater forcing at the surface. The model

  10. Interdecadal North-Atlantic meridional overturning circulation variability in EC-EARTH

    NARCIS (Netherlands)

    Wouters, B.; Drijfhout, D.; Hazeleger, W.

    2012-01-01

    The Atlantic meridional overturning circulation (AMOC) in a 600 years pre-industrial run of the newly developed EC-EARTH model features marked interdecadal variability with a dominant time-scale of 50–60 years. An oscillation of approximately 2 Sverdrup (1 Sv = 106 m3 s-1) is identified, which

  11. Response of the Atlantic overturning circulation to South Atlantic sources of buoyancy

    NARCIS (Netherlands)

    Weijer, W.; Ruijter, W.P.M. de; Sterl, A.; Drijfhout, S.

    2001-01-01

    The heat and salt input from the Indian to Atlantic Oceans by Agulhas Leakage is found to influence the Atlantic overturning circulation in a low-resolution Ocean General Circulation Model. The model used is the Hamburg Large-Scale Geostrophic (LSG) model, which is forced by mixed boundary

  12. Recent increases in Arctic freshwater flux affects Labrador Sea convection and Atlantic overturning circulation

    NARCIS (Netherlands)

    Yang, Qian; Dixon, Timothy H.; Myers, Paul G.; Bonin, Jennifer; Chambers, Don; Van Den Broeke, M. R.

    2016-01-01

    The Atlantic Meridional Overturning Circulation (AMOC) is an important component of ocean thermohaline circulation. Melting of Greenland's ice sheet is freshening the North Atlantic; however, whether the augmented freshwater flux is disrupting the AMOC is unclear. Dense Labrador Sea Water (LSW),

  13. Joint Optimization of Preventive Maintenance and Spare Parts Inventory with Appointment Policy

    Directory of Open Access Journals (Sweden)

    Jing Cai

    2017-01-01

    Full Text Available Under the background of the wide application of condition-based maintenance (CBM in maintenance practice, the joint optimization of maintenance and spare parts inventory is becoming a hot research to take full advantage of CBM and reduce the operational cost. In order to avoid both the high inventory level and the shortage of spare parts, an appointment policy of spare parts is first proposed based on the prediction of remaining useful lifetime, and then a corresponding joint optimization model of preventive maintenance and spare parts inventory is established. Due to the complexity of the model, the combination method of genetic algorithm and Monte Carlo is presented to get the optimal maximum inventory level, safety inventory level, potential failure threshold, and appointment threshold to minimize the cost rate. Finally, the proposed model is studied through a case study and compared with both the separate optimization and the joint optimization without appointment policy, and the results show that the proposed model is more effective. In addition, the sensitivity analysis shows that the proposed model is consistent with the actual situation of maintenance practices and inventory management.

  14. Understanding the Impact of Root Morphology on Overturning Mechanisms: A Modelling Approach

    Science.gov (United States)

    Fourcaud, Thierry; Ji, Jin-Nan; Zhang, Zhi-Qiang; Stokes, Alexia

    2008-01-01

    Background and Aims The Finite Element Method (FEM) has been used in recent years to simulate overturning processes in trees. This study aimed at using FEM to determine the role of individual roots in tree anchorage with regard to different rooting patterns, and to estimate stress distribution in the soil and roots during overturning. Methods The FEM was used to carry out 2-D simulations of tree uprooting in saturated soft clay and loamy sand-like soil. The anchorage model consisted of a root system embedded in a soil block. Two root patterns were used and individual roots removed to determine their contribution to anchorage. Key Results In clay-like soil the size of the root–soil plate formed during overturning was defined by the longest roots. Consequently, all other roots localized within this plate had no influence on anchorage strength. In sand-like soil, removing individual root elements altered anchorage resistance. This result was due to a modification of the shape and size of the root–soil plate, as well as the location of the rotation axis. The tap root and deeper roots had more influence on overturning resistance in sand-like soil compared with clay-like soil. Mechanical stresses were higher in the most superficial roots and also in leeward roots in sand-like soil. The relative difference in stresses between the upper and lower sides of lateral roots was sensitive to root insertion angle. Assuming that root eccentricity is a response to mechanical stresses, these results explain why eccentricity differs depending on root architecture. Conclusions A simple 2-D Finite Element model was developed to better understand the mechanisms involved during tree overturning. It has been shown how root system morphology and soil mechanical properties can modify the shape of the root plate slip surface as well as the position of the rotation axis, which are major components of tree anchorage. PMID:17942593

  15. Overturn of the Oceasn Flow in the North Atlantic as a Trigger of Inertia Motion to Form a Meridional Ocean Circulation

    Science.gov (United States)

    Nakamura, Shigehisa

    2010-05-01

    This work is an introduction of a meridional ocean circulation. As for the zonal motions,there have been many contributions. Recent oceanographic works noticed an overturn of the ocean current in the North Atlantic. The author notices this overturn is a trigger to generate a meridional ocean circulation to have a track through the deep Atlantic, the deep circum-polar current, the deep branch flow to the Pacific between the Australian and the South America. The east part of the branch flow relates to the upwelling off Peru, and the west part relates to form a deep water in the Northwest Pacific. THe overturn of the North Atlantic suggests an outflow of the deep water and a storage of the old aged deep water in the Northwest Pacific. The storage water increase in the Northwest Pacific shoould be a trigger of the swelling up of the sea level mid Pacific to affect to the ocean front variations between the coastal waters and the ocean water. In order to keep a hydrodynamic balance on the earth, an increase of the deep water in the Pacific should flow through the Bering Sea and the Arctic Sea to get to the North Atlantic. It should be noted that a budget of the ocean water flow must be hold the condition of the water masses concservation on the earth surface. This inertia motion is maintained once induced after any natural effect or some man-made influences. At this stage, the author has to notice that there has been developed a meridional inertia path of the air particle as well as the ocean water parcel, nevertheless nobody has had pointed out this inertiamotion with a meridional path in the ocean. Air-sea interaction must be one of the main factors for driving the ocean water though the inertia motion in the global scale is more energetic. To the details, the scientists should pursue what geophysical dynamics must be developed in the future.

  16. THERAPEUTIC EYELIDS HYGIENE IN THE ALGORITHMS OF PREVENTION AND TREATMENT OF OCULAR SURFACE DISEASES. PART II

    Directory of Open Access Journals (Sweden)

    V. N. Trubilin

    2016-01-01

    Full Text Available The second part of the article is focused on the issue of prevention and treatment of the most common clinical situations in which applicable therapeutic hygiene: seborrheic blepharitis; Staphylococcal blepharitis; Allergic blepharitis; barley and chalazion; prevention keratoconjunctival xerosis (during the preoperative and postoperative period, while wearing contact lenses, in computer vision syndrome, in remission after acute inflammation of the conjunctiva and cornea. There is an algorithm for the therapeutic care of eyelids and the basic mechanisms of action of this procedure. Until recently, the treatment of dry eye syndrome involves the use tearsubstitude therapy. Ten or fifteen years ago, 2–3 tearsubstitudes were presented at the domestic market. Currently, there are doses of different forms of artificial tears, while there are hundreds of them on the western pharmaceutical market. The rapid development in the search for new forms tearsubstitudes is not accident. This is due to the increasing number of patients suffering from disorders of the tear membrane stability, which achieves, according to different sources, up to 40–60% of the adult population. It should be noted that the primary cause of dry eye syndrome in 85–95% of patients is meibomian gland’s dysfunction, thus applying tearsubstitudes symptomatic therapy is treatment that does not solve the problem on the pathogenic level. For this reason, conducting therapeutic hygiene century (warm compresses + self-massage is an important component of the treatment of this group of patients. Objective evidence of relevance and effectiveness of therapeutic care age, in our opinion, is the rapid development of the pharmaceutical market in this area. There is a large number of new gels, lotions, wipes and other products for hygiene century every year. Clear algorithms that include therapeutic hygiene century (dates, the indications for the use of certain hygiene products is an actual

  17. FEM for stability analysis against overturning of portal water injection sheet pile

    Science.gov (United States)

    Lingyun, Liu; Haiyan, Guo; Qi, Sun

    2006-07-01

    Portal water injection sheet pile (PWISP), as a retaining wall, appeared in seashore engineering in 2000. Although there have been many systematic methods addressing the issue, there are very few focusing on the new structure because of the difficulties in defining the earth pressure between the two piles. A new method is proposed in this paper to obtain the earth pressure between the PWISPs. Stability analysis against overturning follows as a consequence. Using Finite Element Analysis (FEA) software ANSYS, both the nonlinear characteristics of the soil and thos of the contact elements are taken into account to obtain the earth pressure distribution on the contact surface. Based on the results of the FEA, Rankin's theory and the slip plane theory, the formula of the earth pressure on the inner surfaces between the piles is given. Assuming the PWISP as the analysis object and the earth pressure as an outside force acting upon it, the equation of stability against overturning of the PWISP is presented. Finally, some parameters are discussed about the stability of the PWISP against overturning, such as the embedded depth of the front pile, the distance between the two rows of piles, the internal friction angle and the cohesion of the earth. The results show that the increase of the cohesion and the internal friction angle will decrease the distance and the embedded depth, and therefore enhance the stability against overturning. Specifically, when the distance is 1/3 2/3 of the maximal excavation depth, the two rows of piles give the best performance in stability.

  18. Effect of Interactive River Routing on North Atlantic Overturning in a Simulation of the last Deglaciation

    Science.gov (United States)

    Mikolajewicz, Uwe; Ziemen, Florian; Kapsch, Marie; Meccia, Virna

    2017-04-01

    One of the major challenges in climate modeling is the simulation of glacial-interglacial transitions. A few models of intermediate complexity have been successful in simulating the last termination. Complex atmosphere-ocean general circulation models (AOGCMs) with prescribed ice sheets are able to yield realistic climate changes. Here we present results from our first attempt to simulate a substantial part of the last glacial cycle with an AOGCM coupled interactively with a state-of-the-art ice sheet model. The ECHAM5/MPIOM AOGCM is interactively coupled to the dynamical ice sheet model PISM and the dynamical vegetation model LPJ. The model is integrated from the late Glacial into the Holocene using insolation and greenhouse gas concentrations as transient forcing. To make the long simulations feasible, the atmosphere is accelerated by a factor of 10 relative to the other components using a periodical-synchronous coupling technique. The land sea mask remains fixed at the LGM state. River routing and surface elevation are calculated interactively. A mini-ensemble with different initial conditions is performed. Additionally, one fully synchronously simulation, without acceleration in the atmosphere, is run. In all simulations the northern hemisphere deglaciation starts between 18 and 17 kyr BP, consistent with the onset of global warming. The model produces Heinrich event like variability. These rapid ice discharge events have a strong impact on the North Atlantic meridional overturning circulation (NAMOC). The interactive river routing has a strong impact on the simulated NAMOC during the deglaciation. The retreat of the Laurentide Ice Sheet together with the depressed topography due to the former ice load leads to a redirection of the river routes.. In particular, the discharge route for runoff from the melting southwestern Laurentide shifts from the Gulf of Mexico to the Arctic. The consequence is a rapid reduction/suppression of the North Atlantic deep water

  19. Alzheimer's disease and vascular dementia: one potentially preventable and modifiable disease? Part II: Management, prevention and future perspective.

    Science.gov (United States)

    Davey, Dennis A

    2014-01-01

    The management of dementia and mild cognitive impairment (MCI) includes pharmacological, nonpharmacological and caregiver interventions. Acetyl-cholinesterase inhibitors and memantine have a small beneficial effect in mild-to-moderate dementia. Attention is increasingly focused on long-term measures that may prevent, delay or minimize MCI and dementia, including Mediterranean diet, exercise, early active treatment of hypercholesterolaemia hypertension, and diabetes starting in midlife and earlier. High cognitive activity and a high cognitive reserve may prevent or delay the onset of aging-related MCI and dementia. Although the numbers of the elderly with dementia are rapidly increasing worldwide, the incidence of dementia in some countries is decreasing attributable to higher educational levels, decreased vascular risk factors and healthier lifestyles. Prevention of dementia is feasible and reasonable.

  20. Sensitivity of the overturning circulation of the Baltic Sea to climate change, a numerical experiment

    Science.gov (United States)

    Hordoir, Robinson; Höglund, Anders; Pemberton, Per; Schimanke, Semjon

    2018-02-01

    An ocean model covering the Baltic Sea area is forced by several climate scenarios for a period extending from 1961 to 2100. The Baltic Sea overturning circulation is then analyzed. The analysis shows that this circulation decreases between the end of the 20th century and the end of the 21st century, and that the decrease is amplified in the case of the strongest greenhouse gas emission scenarios, which corresponds with the highest warming cases. The reasons behind this decrease in overturning circulation are investigated. A strong increase of thermal stratification is noticed at the level of the Baltic Sea mixed layer. Based on buoyancy flux considerations, we demonstrate that the decrease in overturning circulation coincides with the increase of thermal stratification. Evidence shows that the underlying process is linked to a smaller erosion of the halocline due to a higher shielding, itself linked with a stronger and longer seasonal thermocline. This theory works if surface wind mixing is not taken into account directly in the computation of buoyancy fluxes.

  1. Rocking motion of structures under earthquakes. Overturning of 2-DOF system

    International Nuclear Information System (INIS)

    Kobayashi, Koichi; Watanabe, Tetsuya; Tanaka, Kihachiro; Tomoda, Akinori

    2011-01-01

    In recent years, huge earthquakes happen, for example, The South Hyogo prefecture Earthquake in 1995, The Mid Niigata Prefecture Earthquake in 2004, The Iwate-Miyagi Nairiku Earthquake in 2008. In The Niigataken Chuetsu-oki Earthquake in 2007, hundreds of drums fell down and water spilled out. A lot of studies about rocking behavior of rigid body had been performed from 1960's. However, these studies were only for a specific condition of the structure size or input vibration characteristics. Therefore, generalizes fall condition for earthquake is required. This paper deals with the analytical and the experimental study of the rocking vibration of 1-DOF rocking system, 2-DOF vibration-rocking system and 2-DOF rocking system under earthquakes. In this study, the equation of motion for each rocking systems are developed. The numerical model of 2-DOF rocking system is evaluated by free rocking experiment. In this paper, 'Overturning Map' which can distinguish whether structures falls or not is proposed. The overturning map of each rocking systems excited by the artificial earthquake wave calculated from the design spectrum is shown. As the result, overturning condition of structures is clarified. (author)

  2. Manual for best practice for emergency response procedures, part 1: causes and prevention of inrushes, fires, explosions and other emergencies.

    CSIR Research Space (South Africa)

    Spencer, KC

    2000-02-01

    Full Text Available Executive Summary This project was designed to have the following outputs: • Recommendations for best practices to deal with coal mine emergencies, with emphasis on inrushes, fires and explosions. • Provide a document from which training staff can... and prevention of inrushes, fires, explosions and other emergencies. Part 2 The management of inrushes, fires, explosions and other emergencies. Part 3 A review of the Department of Minerals and Energy guidelines relevant to inrushes, fires, explosions...

  3. THE FAULTS OF PROTOTYPE PARTS PRODUCED WITH FDM TECHNOLOGY AND PREVENTION OF THESE FAULTS

    OpenAIRE

    MADEN, Hakan; KAMBER, Ömer Şaban

    2018-01-01

    Nowadays, most of the products we use are madefrom plastic parts. After making the design of the products, it is necessary along time and many operations to produce plastic parts. With the developingtechnology, plastic parts are produced in a short time using Fused DepositionModeling (FDM) method. In this study, when the prototype part is produced byFDM method, mistakes originating from the machine principle, part design andpart production are discussed. These faults are the steps on the surf...

  4. Prevention

    Science.gov (United States)

    ... Error processing SSI file About Heart Disease & Stroke Prevention Heart disease and stroke are an epidemic in ... secondhand smoke. Barriers to Effective Heart Disease & Stroke Prevention Many people with key risk factors for heart ...

  5. Modification of the "Preventing Child Abuse and Neglect" (PCAN) Curriculum for IDEA Part C Providers

    Science.gov (United States)

    Kilburn, Janice E.; Shapiro, Cheri J.

    2015-01-01

    Strategic workforce training of organizations that provide services to families of young children with special needs can help strengthen families and prevent child maltreatment, but few curriculua are available for this purpose. One professional development curriculum, "Preventing Child Abuse and Neglect: Parent-Provider Partnerships in Child…

  6. Application of legal measures as part of the policy for prevention of corruption in public sphere: Kosovo case

    Directory of Open Access Journals (Sweden)

    Vilard Bytyqi

    2016-07-01

    Full Text Available This paper will address the application of legal measures as part of the policy of corruption prevention in the public sphere. At present, corruption offenses have become a very dangerous phenomenon for the stability and security of societies, undermining the institutions and values of democracy, ethical values and justice, and jeopardizing the essential development and the rule of law. Knowing that these criminal offenses carry a high social risk and are conducted with high professionalism from people who have the state power, a greater focus should be placed on its prevention. Naturally, the criminal sanctions against criminal acts of corruption have their positive effect, punitive and preventive, but these are the last measures that the state should use. The state of Kosovo in an effort to prevent corruption, has established in legal terms an advanced legislation in accordance with international laws and comparable to developed countries.

  7. 33 CFR Appendix E to Part 273 - Preventive Safety Measures in Handling of Herbicides

    Science.gov (United States)

    2010-07-01

    .... Special care is required to prevent contamination of the inside of gloves. 9. Approved respirators must be... holes in top, bottom, and sides of metal containers or crush them so they cannot collect water or be...

  8. Preventative and predictive maintenance as a function of spare part management

    International Nuclear Information System (INIS)

    LaRose, R.; Sloski, P.

    2006-01-01

    Preventive and predictive maintenance has many aspects, such as vibration monitoring, lubricating oil analysis, thermography etc. This presentation focuses on the material and design application of sealing devices. (author)

  9. The potential of socio-psychological models for the development of prevention programs (Part 1

    Directory of Open Access Journals (Sweden)

    Bovina I.B.

    2014-12-01

    Full Text Available This paper considers the problem of designing prevention programs in health and disease. We note that smoking cessation on the planet would reduce mortality from various types of cancer by 25%, and would also save the lives of hundreds of thousands of people who die each year from heart attacks. Losing weight by only 10% through proper nutrition and exercise would reduce the incidence of cardiovascular disease, as well as certain types of cancer. Based on the literature review, we reveal the different types of prevention, show the importance of preventive measures aimed at the patient's immediate environment. Among the main difficulties associated with the development of effective prevention programs we discuss the following: 1 ignoring the psychological mechanisms of behavior change; 2 irrelevance of media broadcast methods in prevention campaigns; 3 the time between the problem behavior and its negative effects on health. We discuss the potential of social influence models for the development of prevention programs in the field of health and disease.

  10. Antarctic contribution to meltwater pulse 1A from reduced Southern Ocean overturning.

    Science.gov (United States)

    Golledge, N R; Menviel, L; Carter, L; Fogwill, C J; England, M H; Cortese, G; Levy, R H

    2014-09-29

    During the last glacial termination, the upwelling strength of the southern polar limb of the Atlantic Meridional Overturning Circulation varied, changing the ventilation and stratification of the high-latitude Southern Ocean. During the same period, at least two phases of abrupt global sea-level rise--meltwater pulses--took place. Although the timing and magnitude of these events have become better constrained, a causal link between ocean stratification, the meltwater pulses and accelerated ice loss from Antarctica has not been proven. Here we simulate Antarctic ice sheet evolution over the last 25 kyr using a data-constrained ice-sheet model forced by changes in Southern Ocean temperature from an Earth system model. Results reveal several episodes of accelerated ice-sheet recession, the largest being coincident with meltwater pulse 1A. This resulted from reduced Southern Ocean overturning following Heinrich Event 1, when warmer subsurface water thermally eroded grounded marine-based ice and instigated a positive feedback that further accelerated ice-sheet retreat.

  11. The North Atlantic Ocean Is in a State of Reduced Overturning

    Science.gov (United States)

    Smeed, D. A.; Josey, S. A.; Beaulieu, C.; Johns, W. E.; Moat, B. I.; Frajka-Williams, E.; Rayner, D.; Meinen, C. S.; Baringer, M. O.; Bryden, H. L.; McCarthy, G. D.

    2018-02-01

    The Atlantic Meridional Overturning Circulation (AMOC) is responsible for a variable and climatically important northward transport of heat. Using data from an array of instruments that span the Atlantic at 26°N, we show that the AMOC has been in a state of reduced overturning since 2008 as compared to 2004-2008. This change of AMOC state is concurrent with other changes in the North Atlantic such as a northward shift and broadening of the Gulf Stream and altered patterns of heat content and sea surface temperature. These changes resemble the response to a declining AMOC predicted by coupled climate models. Concurrent changes in air-sea fluxes close to the western boundary reveal that the changes in ocean heat transport and sea surface temperature have altered the pattern of ocean-atmosphere heat exchange over the North Atlantic. These results provide strong observational evidence that the AMOC is a major factor in decadal-scale variability of North Atlantic climate.

  12. Interdecadal North-Atlantic meridional overturning circulation variability in EC-EARTH

    International Nuclear Information System (INIS)

    Wouters, Bert; Drijfhout, Sybren; Hazeleger, Wilco

    2012-01-01

    The Atlantic meridional overturning circulation (AMOC) in a 600 years pre-industrial run of the newly developed EC-EARTH model features marked interdecadal variability with a dominant time-scale of 50-60 years. An oscillation of approximately 2 Sverdrup (1 Sv = 10 6 m 3 s -1 ) is identified, which manifests itself as a monopole causing the overturning to simultaneously strengthen (/weaken) and deepen (/shallow) as a whole. Eight years before the AMOC peaks, density in the Labrador-Irminger Sea region reaches a maximum, triggering deep water formation. This density change is caused by a counterclockwise advection of temperature and salinity anomalies at lower latitudes, which we relate to the north-south excursions of the subpolar-subtropical gyre boundary and variations in strength and position of the subpolar gyre and the North Atlantic Current. The AMOC fluctuations are not directly forced by the atmosphere, but occur in a delayed response of the ocean to forcing by the North Atlantic Oscillation, which initiates ''intergyre''-gyre fluctuations. Associated with the AMOC is a 60-year sea surface temperature variability in the Atlantic, with a pattern and timescale showing similarities with the real-world Atlantic Multidecadal Variability. This good agreement with observations lends a certain degree of credibility that the mechanism that is described in this article could be seen as representative of the real climate system. (orig.)

  13. Interdecadal North-Atlantic meridional overturning circulation variability in EC-EARTH

    Energy Technology Data Exchange (ETDEWEB)

    Wouters, Bert; Drijfhout, Sybren; Hazeleger, Wilco

    2012-12-15

    The Atlantic meridional overturning circulation (AMOC) in a 600 years pre-industrial run of the newly developed EC-EARTH model features marked interdecadal variability with a dominant time-scale of 50-60 years. An oscillation of approximately 2 Sverdrup (1 Sv = 10{sup 6} m{sup 3} s{sup -1}) is identified, which manifests itself as a monopole causing the overturning to simultaneously strengthen (/weaken) and deepen (/shallow) as a whole. Eight years before the AMOC peaks, density in the Labrador-Irminger Sea region reaches a maximum, triggering deep water formation. This density change is caused by a counterclockwise advection of temperature and salinity anomalies at lower latitudes, which we relate to the north-south excursions of the subpolar-subtropical gyre boundary and variations in strength and position of the subpolar gyre and the North Atlantic Current. The AMOC fluctuations are not directly forced by the atmosphere, but occur in a delayed response of the ocean to forcing by the North Atlantic Oscillation, which initiates ''intergyre''-gyre fluctuations. Associated with the AMOC is a 60-year sea surface temperature variability in the Atlantic, with a pattern and timescale showing similarities with the real-world Atlantic Multidecadal Variability. This good agreement with observations lends a certain degree of credibility that the mechanism that is described in this article could be seen as representative of the real climate system. (orig.)

  14. Low-frequency oscillations of the Atlantic Ocean meridional overturning circulation in a coupled climate model

    Directory of Open Access Journals (Sweden)

    M. Schulz

    2007-01-01

    Full Text Available Using a 3-dimensional climate model of intermediate complexity we show that the overturning circulation of the Atlantic Ocean can vary at multicentennial-to-millennial timescales for modern boundary conditions. A continuous freshwater perturbation in the Labrador Sea pushes the overturning circulation of the Atlantic Ocean into a bi-stable regime, characterized by phases of active and inactive deep-water formation in the Labrador Sea. In contrast, deep-water formation in the Nordic Seas is active during all phases of the oscillations. The actual timing of the transitions between the two circulation states occurs randomly. The oscillations constitute a 3-dimensional phenomenon and have to be distinguished from low-frequency oscillations seen previously in 2-dimensional models of the ocean. A conceptual model provides further insight into the essential dynamics underlying the oscillations of the large-scale ocean circulation. The model experiments indicate that the coupled climate system can exhibit unforced climate variability at multicentennial-to-millennial timescales that may be of relevance for Holocene climate variations.

  15. An isentropic perspective of the atmospheric overturning induced by Hector the Convector

    Science.gov (United States)

    Dauhut, Thibaut; Chaboureau, Jean-Pierre; Mascart, Patrick; Pauluis, Olivier

    2017-04-01

    The overturning inside Hector the Convector, a tropical multicellular convective system of the Northern Australia that regularly overshoots into the stratosphere, is synthesized at the scale of a Large-Eddy Simulation (Dauhut et al., 2015). The isentropic analysis offers the advantage to filter out the reversible motions due to the gravity waves and to take into account the turbulent fluxes that contribute to the vertical transport. Two key circulations are evidenced: the troposphere-deep overturning and the mass exchange due to the overshoots into the stratosphere. The transition from deep to very deep convection is associated with a change in the diabatic tendency inside the tallest updrafts: the latent heat release due to the freezing of a large amount of hydrometeors overrode the loss of energy due to mixing with the drier, colder air of the environment. In agreement with a previous study of Hector examining the properties of its two tallest updrafts (Dauhut et al., 2016), the entrainment rate exhibits a minimum during the very deep convection phase, as low as 0.04 /km. The two-stream approximation corroborates the Eulerian computation of the vertical mass flux in the mid-troposphere and in the lower stratosphere. It however gives a lower estimate of the flux in the upper troposphere, filtering out the reversible motions, and a larger estimate in the lower troposphere and at the tropopause, where slow vertical motions contribute significantly to the transport.

  16. Closed-form overturning limit of rigid block under critical near-fault ground motions

    Directory of Open Access Journals (Sweden)

    Kunihiko eNabeshima

    2016-05-01

    Full Text Available A closed-form limit on the input level of the double impulse as a substitute of a near-fault ground motion is derived for the overturning of a rigid block. The rocking vibration of the rigid block is formulated by using the conservation law of angular momentum and the conservation law of mechanical energy. The initial rotational velocity after the first impulse and the rotational velocity after the impact are determined by the conservation law of angular momentum. The velocity change after the second impulse is also characterized by the conservation law of angular momentum. The maximum angles of rotation of the rigid block in both the clockwise and anti-clockwise directions, which are needed for the computation of the overturning limit, are derived by the conservation law of mechanical energy. This enables us to avoid the computation of complicated non-linear time-history responses. The critical timing of the second impulse to the first impulse is characterized by the time of impact after the first impulse. It is clarified that the action of the second impulse just after the impact corresponds to the critical timing. It is derived from the closed-form expression of the critical velocity amplitude limit of the double impulse that its limit is proportional to the square root of size, i.e. the scale effect.

  17. An Anthropogenic Radioisotope, Iodine 129, As A Tracer For Studying The Northern Limb of The Meridional Overturning Circulation (moc)

    Science.gov (United States)

    Gascard, J. C.; Raisbeck, G.; Yiou, F.; Sequeira, S.; Mork, K. A.

    A number of observations taken during the 1990s, seem to corroborate the fact that the northern limb of the Meridional Overturning Circulation (the so-called MOC), is undergoing large scale variability. Arctic Sea-Ice thinning, Overflows slackening, Labrador and Greenland Seas Deep Convection weakening, have recently been re- ported. Can this large scale variability be interpreted as a natural variability of the MOC or is it more related to global changes due to anthropogenic effects like green- house gases enhancing Global Warming at High Latitudes ? Iodine 129 resulting from reprocessing nuclear wastes at La Hague (France) and Sellafield (UK), has penetrated through all the various parts of the MOC from the Source: the Norwegian Coastal Current (NCC) collecting Iodine 129 from the North Sea, to the Sink: the Greenland- Iceland-Scotland Overflows and ultimately to the North Atlantic Deep Waters via the Deep Western Boundary Current. During recent years, discharges of Iodine 129 have increased drastically and peaks in Iodine 129 concentrations have already been ob- served all along the coast of Norway. In this talk, we will first present the most recent results showing the transfer of Iodine 129 through the various parts of the MOC from the NCC down to the North Atlantic Overflows (Denmark Strait), and second, explain how this results allow us to improve our understanding of the MOC system and in particular its variability. This is an important issue for improving reliability of actual numerical simulations of past, present and future behavior of the MOC, which has strong implications for climate related problems.

  18. 14 CFR Appendix A to Part 43 - Major Alterations, Major Repairs, and Preventive Maintenance

    Science.gov (United States)

    2010-01-01

    ..., and control surfaces. (xxviii) Repairing, including rebottoming, of removable or integral fuel tanks and oil tanks. (2) Powerplant major repairs. Repairs of the following parts of an engine and repairs... of fuel tank filler openings provided the specific device has been made a part of the aircraft type...

  19. Proposed national strategies for the prevention of leading work-related diseases and injuries. Part 1

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    Preliminary strategies developed at the National Symposium on the Prevention of Leading Work Related Diseases and Injuries, held in Atlanta, Georgia on May 1 to 3, 1985 were revised, elaborated, and further developed. Strategies were developed for the prevention of occupational lung diseases, musculoskeletal injuries, occupational cancers, severe occupational traumatic injuries, and occupational cardiovascular diseases. Lung diseases considered included silicosis, asbestosis, lung cancer mesothelioma, coal workers' pneumoconiosis, byssinosis, occupational asthma, hypersensitivity pneumonitis, asphyxiation, irritation, pulmonary edema, brucellosis, psitticosis, anthrax, mycobacterioses, histoplasmosis, aspergillosis, and coccidioidomycosis. Occupational cancers were discussed as they occur in the lung, pleura, peritoneum, bladder, kidneys, blood, nasal cavity, skin, nasal sinuses, and liver.

  20. Dietary prevention of allergic diseases in infants and small children. Part III

    DEFF Research Database (Denmark)

    Muraro, Antonella; Dreborg, Sten; Halken, Susanne

    2004-01-01

    diseases in high-risk children. In these patients breastfeeding combined with avoidance of solid food and cow's milk for at least 4-6 months is the most effective preventive regimen. In the absence of breast milk, formulas with documented reduced allergenicity for at least 4-6 months should be used....

  1. Dietary prevention of allergic diseases in infants and small children. Part I

    DEFF Research Database (Denmark)

    Muraro, Antonella; Dreborg, Sten; Halken, Susanne

    2004-01-01

    . Sensitization to food allergens occurs in the first year of life and cow's milk allergy is the first food allergy to appear in the susceptible infants. Hypoallergenicity of food formulas to be used is a critical issue both for treatment of cow's milk-allergic children and for prevention. Methods to document...

  2. State Part C Agency Practices and the Child Abuse Prevention and Treatment Act (CAPTA)

    Science.gov (United States)

    Stahmer, Aubyn C.; Sutton, Danielle Thorp; Fox, Lise; Leslie, Laurel K.

    2008-01-01

    Each year nearly 900,000 cases of child abuse and neglect are substantiated in the United States, with the highest rates of maltreatment occurring among infants and toddlers. Children exposed to maltreatment are at increased risk of developmental delay. The Child Abuse Prevention and Treatment Act specifies that children under age 3 with…

  3. Clinical approaches to low back pain. Part 1. Epidemiology, diagnosis, and prevention.

    OpenAIRE

    Teasell, R. W.; White, K.

    1994-01-01

    The epidemiology and difficulties in diagnosing low back pain are discussed. Clinical investigations should be limited to those tests that will provide useful information for effective management. Prevention is the best strategy for avoiding low back pain but is realistically hard to practise because the disorder has many environmental and intrinsic risk factors.

  4. Prevention

    Science.gov (United States)

    ... Contact Aging & Health A to Z Find a Geriatrics Healthcare Professional Medications & Older Adults Making Your Wishes ... Prevention Hearing Loss Heart Attack High Blood Pressure Nutrition Osteoporosis Shingles Skin Cancer Related News Quitting Smoking, ...

  5. Impact of the Indonesian Throughflow on the Atlantic Meridional Overturning Circulation

    Science.gov (United States)

    Le Bars, Dewi; Dijkstra, Henk

    2014-05-01

    Understanding the mechanisms controlling the strength and variability of the Atlantic Meridional Overturning Circulation (AMOC) is one of the main topics of climate science and in particular physical oceanography. Current simple representations of the global ocean overturning separates the surface return flow to the Atlantic basin into a cold water path through the Drake Passage and a warm water path through the Indonesian Throughflow and Agulhas leakage. The relative importance of these two paths has been investigated in non-eddying ocean models. In these models the Agulhas retroflection cannot be modelled properly, which leads to an important overestimation of the Agulhas leakage. Furthermore, it seems that the in these models the relation between the meridional density gradient and the overturning strength is greatly simplified and changes significantly when eddies are resolved (Den Toom et al. 2013). As a result, the impact of the Pacific-Indian Oceans exchange through the Indonesian Throughflow on the AMOC is still unknown. To investigate this question we run a state-of-the-art ocean model, the Parallel Ocean Program (POP), globally, at eddy resolving resolution (0.1º). Using climatological forcing from the CORE dataset we perform two simulations of 110 years, a control experiment with realistic coastlines and one in which the Indonesian Passages are closed. Results show that, for a closed Indonesian Throughflow, the Indian Ocean cools down but its salinity increases. The Agulhas leakage reduces also by 3Sv (Le Bars et al. 2013) and the net effect on the south Atlantic is a cooling down and decrease salinity. The anomalies propagate slowly northward and a significant decrease of the AMOC is found at 26ºN after 50 years. This decrease AMOC also leads to reduced northward heat flux in the Atlantic. These processes are investigated with a detailed analysis of the heat and freshwater balances in the Atlantic-Arctic region and in the region south of 34ºS where

  6. Moving alcohol prevention research forward-Part I: introducing a complex systems paradigm.

    Science.gov (United States)

    Apostolopoulos, Yorghos; Lemke, Michael K; Barry, Adam E; Lich, Kristen Hassmiller

    2018-02-01

    The drinking environment is a complex system consisting of a number of heterogeneous, evolving and interacting components, which exhibit circular causality and emergent properties. These characteristics reduce the efficacy of commonly used research approaches, which typically do not account for the underlying dynamic complexity of alcohol consumption and the interdependent nature of diverse factors influencing misuse over time. We use alcohol misuse among college students in the United States as an example for framing our argument for a complex systems paradigm. A complex systems paradigm, grounded in socio-ecological and complex systems theories and computational modeling and simulation, is introduced. Theoretical, conceptual, methodological and analytical underpinnings of this paradigm are described in the context of college drinking prevention research. The proposed complex systems paradigm can transcend limitations of traditional approaches, thereby fostering new directions in alcohol prevention research. By conceptualizing student alcohol misuse as a complex adaptive system, computational modeling and simulation methodologies and analytical techniques can be used. Moreover, use of participatory model-building approaches to generate simulation models can further increase stakeholder buy-in, understanding and policymaking. A complex systems paradigm for research into alcohol misuse can provide a holistic understanding of the underlying drinking environment and its long-term trajectory, which can elucidate high-leverage preventive interventions. © 2017 Society for the Study of Addiction.

  7. OCEAN CIRCULATION. Observing the Atlantic Meridional Overturning Circulation yields a decade of inevitable surprises.

    Science.gov (United States)

    Srokosz, M A; Bryden, H L

    2015-06-19

    The importance of the Atlantic Meridional Overturning Circulation (AMOC) heat transport for climate is well acknowledged. Climate models predict that the AMOC will slow down under global warming, with substantial impacts, but measurements of ocean circulation have been inadequate to evaluate these predictions. Observations over the past decade have changed that situation, providing a detailed picture of variations in the AMOC. These observations reveal a surprising degree of AMOC variability in terms of the intraannual range, the amplitude and phase of the seasonal cycle, the interannual changes in strength affecting the ocean heat content, and the decline of the AMOC over the decade, both of the latter two exceeding the variations seen in climate models. Copyright © 2015, American Association for the Advancement of Science.

  8. Effects of Southern Hemisphere Wind Changes on the Meridional Overturning Circulation in Ocean Models.

    Science.gov (United States)

    Gent, Peter R

    2016-01-01

    Observations show that the Southern Hemisphere zonal wind stress maximum has increased significantly over the past 30 years. Eddy-resolving ocean models show that the resulting increase in the Southern Ocean mean flow meridional overturning circulation (MOC) is partially compensated by an increase in the eddy MOC. This effect can be reproduced in the non-eddy-resolving ocean component of a climate model, providing the eddy parameterization coefficient is variable and not a constant. If the coefficient is a constant, then the Southern Ocean mean MOC change is balanced by an unrealistically large change in the Atlantic Ocean MOC. Southern Ocean eddy compensation means that Southern Hemisphere winds cannot be the dominant mechanism driving midlatitude North Atlantic MOC variability.

  9. Reduced interdecadal variability of Atlantic Meridional Overturning Circulation under global warming.

    Science.gov (United States)

    Cheng, Jun; Liu, Zhengyu; Zhang, Shaoqing; Liu, Wei; Dong, Lina; Liu, Peng; Li, Hongli

    2016-03-22

    Interdecadal variability of the Atlantic Meridional Overturning Circulation (AMOC-IV) plays an important role in climate variation and has significant societal impacts. Past climate reconstruction indicates that AMOC-IV has likely undergone significant changes. Despite some previous studies, responses of AMOC-IV to global warming remain unclear, in particular regarding its amplitude and time scale. In this study, we analyze the responses of AMOC-IV under various scenarios of future global warming in multiple models and find that AMOC-IV becomes weaker and shorter with enhanced global warming. From the present climate condition to the strongest future warming scenario, on average, the major period of AMOC-IV is shortened from ∼50 y to ∼20 y, and the amplitude is reduced by ∼60%. These reductions in period and amplitude of AMOC-IV are suggested to be associated with increased oceanic stratification under global warming and, in turn, the speedup of oceanic baroclinic Rossby waves.

  10. A reconstructed South Atlantic Meridional Overturning Circulation time series since 1870

    Science.gov (United States)

    Lopez, Hosmay; Goni, Gustavo; Dong, Shenfu

    2017-04-01

    This study reconstructs a century-long South Atlantic Meridional Overturning Circulation (SAMOC) index. The reconstruction is possible due to its covariability with sea surface temperature (SST). A singular value decomposition (SVD) method is applied to the correlation matrix of SST and SAMOC. The SVD is performed on the trained period (1993 to present) for which Expendable Bathythermographs and satellite altimetry observations are available. The joint modes obtained are used in the reconstruction of a monthly SAMOC time series from 1870 to present. The reconstructed index is highly correlated to the observational based SAMOC time series during the trained period and provides a long historical estimate. It is shown that the Interdecadal Pacific Oscillation (IPO) is the leading mode of SAMOC-SST covariability, explaining 85% with the Atlantic Niño accounting for less than 10%. The reconstruction shows that SAMOC has recently shifted to an anomalous positive period, consistent with a recent positive shift of the IPO.

  11. Recent increases in Arctic freshwater flux affects Labrador Sea convection and Atlantic overturning circulation.

    Science.gov (United States)

    Yang, Qian; Dixon, Timothy H; Myers, Paul G; Bonin, Jennifer; Chambers, Don; van den Broeke, M R

    2016-01-22

    The Atlantic Meridional Overturning Circulation (AMOC) is an important component of ocean thermohaline circulation. Melting of Greenland's ice sheet is freshening the North Atlantic; however, whether the augmented freshwater flux is disrupting the AMOC is unclear. Dense Labrador Sea Water (LSW), formed by winter cooling of saline North Atlantic water and subsequent convection, is a key component of the deep southward return flow of the AMOC. Although LSW formation recently decreased, it also reached historically high values in the mid-1990s, making the connection to the freshwater flux unclear. Here we derive a new estimate of the recent freshwater flux from Greenland using updated GRACE satellite data, present new flux estimates for heat and salt from the North Atlantic into the Labrador Sea and explain recent variations in LSW formation. We suggest that changes in LSW can be directly linked to recent freshening, and suggest a possible link to AMOC weakening.

  12. Reduced interdecadal variability of Atlantic Meridional Overturning Circulation under global warming

    Science.gov (United States)

    Cheng, Jun; Liu, Zhengyu; Zhang, Shaoqing; Liu, Wei; Dong, Lina; Liu, Peng; Li, Hongli

    2016-03-01

    Interdecadal variability of the Atlantic Meridional Overturning Circulation (AMOC-IV) plays an important role in climate variation and has significant societal impacts. Past climate reconstruction indicates that AMOC-IV has likely undergone significant changes. Despite some previous studies, responses of AMOC-IV to global warming remain unclear, in particular regarding its amplitude and time scale. In this study, we analyze the responses of AMOC-IV under various scenarios of future global warming in multiple models and find that AMOC-IV becomes weaker and shorter with enhanced global warming. From the present climate condition to the strongest future warming scenario, on average, the major period of AMOC-IV is shortened from ˜50 y to ˜20 y, and the amplitude is reduced by ˜60%. These reductions in period and amplitude of AMOC-IV are suggested to be associated with increased oceanic stratification under global warming and, in turn, the speedup of oceanic baroclinic Rossby waves.

  13. The Preventive and Curative Effects of Fresh Garlic Extract And its Aerial Parts on Fibrosarcoma in Balb/c Mice

    Directory of Open Access Journals (Sweden)

    M Rafieian-kopaei

    2012-05-01

    Full Text Available Introduction: Garlic has been demonstrated to have anticancer activity in some studies; however its effect on fibrosarcoma is not evident. This study intends to examine the preventive and curative effects of fresh garlic extract and its aerial parts on the growth of WEHI-164 fibrosarcoma cells in Balb/c mice. Methods: In this preclinical study, 48 female inbred Balb/c mice(6 to 7 weeks old were divided in to 6 groups of 8 each. A single aliquot of WEHI-164 cells(5 × 106 cells/100 μl was injected subcutaneously in the chest of animal. Two weeks before or three weeks after cell injection, 0.2 cc of normal saline or 20 mg/kg extract of garlic or its aerial parts were injected intraperitoneally(IP to the Balb/c mice. The tumors sizes were compared with each other, using ANOVA test. The antioxidant potential and total phenolic compounds of the extracts were also assessed. Results: The mean sizes of tumor growth in groups which received fresh garlic extract or its aerial parts were smaller than that of control group. However this difference was significant on the 21st day only in garlic extract group(p<0.05. The antioxidant power of fresh garlic involved 35.6%, whereas for its aerial parts it was 15.3%. Moreover, the general amount of phenol in fresh garlic was 12.61 mg/g and in its aerial parts was 2.44 mg/g. Conclusion: Garlic consumption might have a crucial role in prevention and control of fibrosarcoma growth. Furthermore, the phenolic compounds and antioxidant activity of garlic aerial parts are less in comparison to garlic itself, however, higher doses might have anticancer activity

  14. Meridional overturning circulation conveys fast acidification to the deep Atlantic Ocean

    Science.gov (United States)

    Perez, Fiz F.; Fontela, Marcos; García-Ibáñez, Maribel I.; Mercier, Herlé; Velo, Anton; Lherminier, Pascale; Zunino, Patricia; de La Paz, Mercedes; Alonso-Pérez, Fernando; Guallart, Elisa F.; Padin, Xose A.

    2018-02-01

    Since the Industrial Revolution, the North Atlantic Ocean has been accumulating anthropogenic carbon dioxide (CO2) and experiencing ocean acidification, that is, an increase in the concentration of hydrogen ions (a reduction in pH) and a reduction in the concentration of carbonate ions. The latter causes the ‘aragonite saturation horizon’—below which waters are undersaturated with respect to a particular calcium carbonate, aragonite—to move to shallower depths (to shoal), exposing corals to corrosive waters. Here we use a database analysis to show that the present rate of supply of acidified waters to the deep Atlantic could cause the aragonite saturation horizon to shoal by 1,000-1,700 metres in the subpolar North Atlantic within the next three decades. We find that, during 1991-2016, a decrease in the concentration of carbonate ions in the Irminger Sea caused the aragonite saturation horizon to shoal by about 10-15 metres per year, and the volume of aragonite-saturated waters to reduce concomitantly. Our determination of the transport of the excess of carbonate over aragonite saturation (xc[CO32-])—an indicator of the availability of aragonite to organisms—by the Atlantic meridional overturning circulation shows that the present-day transport of carbonate ions towards the deep ocean is about 44 per cent lower than it was in preindustrial times. We infer that a doubling of atmospheric anthropogenic CO2 levels—which could occur within three decades according to a ‘business-as-usual scenario’ for climate change—could reduce the transport of xc[CO32-] by 64-79 per cent of that in preindustrial times, which could severely endanger cold-water coral habitats. The Atlantic meridional overturning circulation would also export this acidified deep water southwards, spreading corrosive waters to the world ocean.

  15. Variations of the Atlantic meridional overturning circulation in control and transient simulations of the last millennium

    Directory of Open Access Journals (Sweden)

    D. Hofer

    2011-02-01

    Full Text Available The variability of the Atlantic meridional overturing circulation (AMOC strength is investigated in control experiments and in transient simulations of up to the last millennium using the low-resolution Community Climate System Model version 3. In the transient simulations the AMOC exhibits enhanced low-frequency variability that is mainly caused by infrequent transitions between two semi-stable circulation states which amount to a 10 percent change of the maximum overturning. One transition is also found in a control experiment, but the time-varying external forcing significantly increases the probability of the occurrence of such events though not having a direct, linear impact on the AMOC. The transition from a high to a low AMOC state starts with a reduction of the convection in the Labrador and Irminger Seas and goes along with a changed barotropic circulation of both gyres in the North Atlantic and a gradual strengthening of the convection in the Greenland-Iceland-Norwegian (GIN Seas. In contrast, the transition from a weak to a strong overturning is induced by decreased mixing in the GIN Seas. As a consequence of the transition, regional sea surface temperature (SST anomalies are found in the midlatitude North Atlantic and in the convection regions with an amplitude of up to 3 K. The atmospheric response to the SST forcing associated with the transition indicates a significant impact on the Scandinavian surface air temperature (SAT in the order of 1 K. Thus, the changes of the ocean circulation make a major contribution to the Scandinavian SAT variability in the last millennium.

  16. Prevention

    DEFF Research Database (Denmark)

    Halken, S; Høst, A

    2001-01-01

    , breastfeeding should be encouraged for 4-6 months. In high-risk infants a documented extensively hydrolysed formula is recommended if exclusive breastfeeding is not possible for the first 4 months of life. There is no evidence for preventive dietary intervention neither during pregnancy nor lactation...... populations. These theories remain to be documented in proper, controlled and prospective studies. Breastfeeding and the late introduction of solid foods (>4 months) is associated with a reduced risk of food allergy, atopic dermatitis, and recurrent wheezing and asthma in early childhood. In all infants....... Preventive dietary restrictions after the age of 4-6 months are not scientifically documented....

  17. 12 CFR Appendix J to Part 717 - Interagency Guidelines on Identity Theft Detection, Prevention, and Mitigation

    Science.gov (United States)

    2010-01-01

    ... the formulation and maintenance of a Program that satisfies the requirements of § 717.90 of this part..., monitoring transactions, and verifying the validity of change of address requests, in the case of existing... of accounts that the federal credit union offers or maintains; and (e) Changes in the business...

  18. DOGMAS AND UPDATES ON THE USE OF BETA-BLOCKERS IN SECONDARY PREVENTION. FIRST PART.

    Directory of Open Access Journals (Sweden)

    Alberto Morales Salinas

    2011-08-01

    Full Text Available There is consensus on clinical guidelines that beta-blockers (BB provide unquestionable benefits in several environments of secondary prevention, such as heart failure and myocardial infarction. However, in everyday practice they are underused in contexts where they are not contraindicated. Such is the case of heart failure with ejection fraction. This article presents an analysis on the available evidence of beta blockers’ effectiveness in heart failure with ejection fraction. It is concluded that overwhelming evidence favours the use of beta-blockers in chronic heart failure with ejection fraction, whereas in episodes of acute decompensated heart failure, their suspension should be avoided whenever it is possible.

  19. An Effective Psychoeducational Intervention for Early Childhood Caries Prevention: Part I

    Science.gov (United States)

    Weber-Gasparoni, Karin; Reeve, Johnmarshall; Ghosheh, Natalie; Warren, Joh J.; Drake, David R.; Kramer, Katherine W.O.; Dawson, Deborah V.

    2016-01-01

    Purpose The purpose was to compare whether mothers exposed to an autonomy-supportive psychoeducational videotaped message, informed by the self-determination theory (SDT), demonstrated greater changes in oral health knowledge and behavioral intentions as a preventive means for early childhood caries (ECC) than mothers exposed to a neutral message delivered by brochure. Methods Data were collected at baseline, one-, and six-month follow-ups from 415 12- to 49-month-old WIC-enrolled children and their mothers: 283 in the video intervention group and 132 in the brochure control group. Mothers completed questionnaires on maternal knowledge and behavioral intentions for oral health care. Chi-square, Wilcoxon rank-sum, and Mann-Whitney tests were used to analyze data (P<.05). Results Relative to their baseline scores, the intervention group showed a greater increase in knowledge than the control group, both at one-month (P=.002) and six-month follow-ups (P<.001). The video group also demonstrated a greater increase in behavioral intentions than controls, both at one-month (P<.05) and six-month follow-ups (P<.001). Knowledge and behavioral intention levels at six-month follow-up did not differ significantly from those at one-month follow-up, indicating that intervention-based increases in these measures were maintained over time. Conclusions Data provided evidence of the effectiveness of the autonomy-supportive psychoeducational intervention for ECC prevention relative to a neutral brochure. PMID:23756308

  20. Internal control as part of prevention irregularities in accounting of budgetary institution

    Directory of Open Access Journals (Sweden)

    O.М. Bunda

    2016-07-01

    Full Text Available The article researches the principles of internal control, the importance, the rationale for the essence of the system of internal control and the legislative building in budgetary institution. It describes the main challenges and problems of practical application of internal control in the normal course of business in modern enterprises. It reveals the following elements of the internal control of a budget institution as: control environment, risk assessment process of a budget institution, information systems, control procedures and control monitoring. The dependence between the effectiveness of accounting and internal control of a budget institution is determined. The paper highlights the methods of evaluation of internal control of a budget institution. This method is recommended for use in the preliminary assessment of control risk budget institution. The concept of «decision» as on the whole and also in particular in internal control is covered. The essential grouping indications of internal control decisions are defined and every type of decisions is characterized. The main directions of improvement of internal control to prevent violations in accounting of a budgetary institution is examined.

  1. Towards a fair consideration of PrEP as part of combination HIV prevention in Latin America.

    Science.gov (United States)

    Ravasi, Giovanni; Grinsztejn, Beatriz; Baruch, Ricardo; Guanira, Juan Vicente; Luque, Ricardo; Cáceres, Carlos F; Ghidinelli, Massimo

    2016-01-01

    Despite progress in scaling up antiretroviral treatment, HIV prevention strategies have not been successful in significantly curbing HIV incidence in Latin America. HIV prevention interventions need to be expanded to target the most affected key populations with a combination approach, including new high impact technologies. Oral pre-exposure prophylaxis (PrEP) is recommended as additional prevention choice for individuals at higher risk of infection and could become a cost-effective prevention tool. We discuss the barriers and solutions for a fair consideration of PrEP as part of combination HIV prevention strategies in Latin America. Although demonstration projects are ongoing or being planned in a number of countries, to date no Latin American country has implemented a public PrEP programme. The knowledge of policymakers about PrEP implementation needs to be strengthened, and programmatic guidance and cost estimate tools need to be developed to support adequate planning. Despite high levels of awareness among health providers, especially if engaged in HIV or key population care, willingness to prescribe PrEP is still low due to the lack of national policies and guidelines. Key populations, especially men who have sex with men, transgender women and sex workers, have been engaged in demonstration projects, and qualitative research shows high awareness and willingness to use PrEP, especially if accessible in the public sector for free or at affordable price. Concerns of safety, adherence, effectiveness and risk compensation need to be addressed through targeted social communication strategies to improve PrEP knowledge and stimulate demand. Alliance among policymakers, civil society and representatives from key populations, healthcare providers and researchers will be critical for the design and successful implementation of PrEP demonstration projects of locally adapted delivery models. The use of mechanisms of joint negotiation and procurement of antiretrovirals

  2. Long term effects of preventive activities of youth health care in The Netherlands: results of a four-part study

    Directory of Open Access Journals (Sweden)

    Pieter A. Wiegersma

    2004-12-01

    Full Text Available

    Background. In this article the results are presented of a four part study on the effect of screening for scoliosis and (repeated well-care visits and freely accessible consultation hours at secondary schools, on the incidence and prevalence of (parasuicide, mental health, adolescent health compromising behaviour and lastly obesity.

    Methods. An ecologic case-referent study design was used with data from the Netherlands Bureau of Statistics, the Ministry of Defence, the 1992 High-School Student Study, all of the youth health care departments in The Netherlands and relevant censuses.

    Results. Attention to mental and physical health and health compromising behaviour, either during screening, open consultation hours or during well-care visits seems to be ineffective and in some instances even detrimental to youth health.

    Of the 18 different outcome measurements, 5 were significantly negative and none were significantly positive.

    Conclusions. This four part study does not support the hypothesis that on a population level, the preventive activities of youth health care departments such as screening for scoliosis, (more frequent well-care visits or offering open consultation hours at secondary schools, have a beneficial effect on prevention of (parasuicide, poor mental health, health compromising behaviour or obesity.

  3. Duration of a Magma Ocean and Subsequent Mantle Overturn in Mars: Evidence from Nakhlites

    Science.gov (United States)

    Debaille, V.; Brandon, A. D.; Yin, Q.-Z.; Jacobsen, B.

    2008-01-01

    It is now generally accepted that the heat produced by accretion, short-lived radioactive elements such as Al-26, and gravitational energy from core formation was sufficient to at least partially melt the silicate portions of terrestrial planets resulting in a global-scale magma ocean. More particularly, in Mars, the geochemical signatures displayed by shergottites, are likely inherited from the crystallization of this magma ocean. Using the short-lived chronometer Sm-146 - Nd-142 (t(sup 1/2) = 103 Myr), the duration of the Martian magma ocean (MMO) has been evaluated to being less than 40 Myr, while recent and more precise ND-142/ND-144 data were used to evaluate the longevity of the MMO to approximately 100 Myr after the solar system formation. In addition, it has been proposed that the end of the crystallization of the MMO may have triggered a mantle overturn, as a result of a density gradient in the cumulate layers crystallized at different levels. Dating the mantle overturn could hence provide additional constraint on the duration of the MMO. Among SNC meteorites, nakhlites are characterized by high epsilon W-182 of approximately +3 and an epsilon Nd-142 similar to depleted shergottites of +0.6-0.9. It has hence been proposed that the source of nakhlites was established very early in Mars history (approximately 8-10 Myr). However, the times recorded in HF-182-W-182 isotope system, i.e. when 182Hf became effectively extinct (approximately 50 Myr after solar system formation) are less than closure times recorded in the Sm-146-Nd-142 isotope system (with a full coverage of approximately 500 Myr after solar system formation). This could result in decoupling between the present-day measured epsilon W-182 and epsilon Nd-142 as the SM-146 may have recorded later differentiation events in epsilon ND-142 not observed in epsilon W-182 values. With these potential complexities in short-lived chronological data for SNC's in mind, new Hf-176/Hf-177, Nd-143/Nd-144 and Nd

  4. An electrical analogy relating the Atlantic multidecadal oscillation to the Atlantic meridional overturning circulation.

    Directory of Open Access Journals (Sweden)

    Bruce E Kurtz

    Full Text Available The Atlantic meridional overturning circulation (AMOC is the northward flow of surface water to subpolar latitudes where deepwater is formed, balanced by southward abyssal flow and upwelling in the vicinity of the Southern Ocean. It is generally accepted that AMOC flow oscillates with a period of 60-80 years, creating a regular variation in North Atlantic sea surface temperature known as the Atlantic multidecadal oscillation (AMO. This article attempts to answer two questions: how is the AMOC driven and why does it oscillate? Using methods commonly employed by chemical engineers for analyzing processes involving flowing liquids, apparently not previously applied to trying to understand the AMOC, an equation is developed for AMOC flow as a function of the meridional density gradient or the corresponding temperature gradient. The equation is based on the similarity between the AMOC and an industrial thermosyphon loop cooler, which circulates a heat transfer liquid without using a mechanical pump. Extending this equation with an analogy between the flow of heat and electricity explains why the AMOC flow oscillates and what determines its period. Calculated values for AMOC flow and AMO oscillation period are in good agreement with measured values.

  5. Plausible Effect of Weather on Atlantic Meridional Overturning Circulation with a Coupled General Circulation Model

    Science.gov (United States)

    Liu, Zedong; Wan, Xiuquan

    2018-04-01

    The Atlantic meridional overturning circulation (AMOC) is a vital component of the global ocean circulation and the heat engine of the climate system. Through the use of a coupled general circulation model, this study examines the role of synoptic systems on the AMOC and presents evidence that internally generated high-frequency, synoptic-scale weather variability in the atmosphere could play a significant role in maintaining the overall strength and variability of the AMOC, thereby affecting climate variability and change. Results of a novel coupling technique show that the strength and variability of the AMOC are greatly reduced once the synoptic weather variability is suppressed in the coupled model. The strength and variability of the AMOC are closely linked to deep convection events at high latitudes, which could be strongly affected by the weather variability. Our results imply that synoptic weather systems are important in driving the AMOC and its variability. Thus, interactions between atmospheric weather variability and AMOC may be an important feedback mechanism of the global climate system and need to be taken into consideration in future climate change studies.

  6. The modern and glacial overturning circulation in the Atlantic ocean in PMIP coupled model simulations

    Directory of Open Access Journals (Sweden)

    S. L. Weber

    2007-01-01

    Full Text Available This study analyses the response of the Atlantic meridional overturning circulation (AMOC to LGM forcings and boundary conditions in nine PMIP coupled model simulations, including both GCMs and Earth system Models of Intermediate Complexity. Model results differ widely. The AMOC slows down considerably (by 20–40% during the LGM as compared to the modern climate in four models, there is a slight reduction in one model and four models show a substantial increase in AMOC strength (by 10–40%. It is found that a major controlling factor for the AMOC response is the density contrast between Antarctic Bottom Water (AABW and North Atlantic Deep Water (NADW at their source regions. Changes in the density contrast are determined by the opposing effects of changes in temperature and salinity, with more saline AABW as compared to NADW consistently found in all models and less cooling of AABW in all models but one. In only two models is the AMOC response during the LGM directly related to the response in net evaporation over the Atlantic basin. Most models show large changes in the ocean freshwater transports into the basin, but this does not seem to affect the AMOC response. Finally, there is some dependence on the accuracy of the control state.

  7. Interdecadal variability of the meridional overturning circulation as an ocean internal mode

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Xiuhua [Universitaet Hamburg, Meteorologisches Institut, Hamburg (Germany); Jungclaus, Johann [Max-Planck-Institut fuer Meteorologie, Hamburg (Germany)

    2008-11-15

    The meridional overturning circulation (MOC) in the coupled ECHAM5/MPIOM exhibits variability at periods of near 30 years and near 60 years. The 30-year variability, referred to as interdecadal variability (IDV), exist in an ocean model driven by climatological atmospheric forcing, suggesting that it is maintained by ocean dynamics; the 60-year variability, the multidecadal variability (MDV), is only observed in the fully coupled model and therefore is interpreted as an atmosphere-ocean coupled mode. The coexistence of the 30-year IDV and the 60-year MDV provides a possible explanation for the widespread time scales observed in climate variables. Further analyses of the climatologically forced ocean model shows that, the IDV is related to the interplay between the horizontal temperature-dominated density gradients and the ocean circulation: temperature anomalies move along the cyclonic subpolar gyre leading to fluctuations in horizontal density gradients and the subsequent weakening and strengthening of the MOC. This result is consistent with that from less complex models, indicating the robustness of the IDV. We further show that, along the North Atlantic Current path, the sea surface temperature anomalies are determined by the slow LSW advection at the intermediate depth. (orig.)

  8. Influence of glacial ice sheets on the Atlantic meridional overturning circulation through surface wind change

    Science.gov (United States)

    Sherriff-Tadano, Sam; Abe-Ouchi, Ayako; Yoshimori, Masakazu; Oka, Akira; Chan, Wing-Le

    2018-04-01

    Coupled modeling studies have recently shown that the existence of the glacial ice sheets intensifies the Atlantic meridional overturning circulation (AMOC). However, most models show a strong AMOC in their simulations of the Last Glacial Maximum (LGM), which is biased compared to reconstructions that indicate both a weaker and stronger AMOC during the LGM. Therefore, a detailed investigation of the mechanism behind this intensification of the AMOC is important for a better understanding of the glacial climate and the LGM AMOC. Here, various numerical simulations are conducted to focus on the effect of wind changes due to glacial ice sheets on the AMOC and the crucial region where the wind modifies the AMOC. First, from atmospheric general circulation model experiments, the effect of glacial ice sheets on the surface wind is evaluated. Second, from ocean general circulation model experiments, the influence of the wind stress change on the AMOC is evaluated by applying wind stress anomalies regionally or at different magnitudes as a boundary condition. These experiments demonstrate that glacial ice sheets intensify the AMOC through an increase in the wind stress at the North Atlantic mid-latitudes, which is induced by the North American ice sheet. This intensification of the AMOC is caused by the increased oceanic horizontal and vertical transport of salt, while the change in sea ice transport has an opposite, though minor, effect. Experiments further show that the Eurasian ice sheet intensifies the AMOC by directly affecting the deep-water formation in the Norwegian Sea.

  9. A coupled model study on the Atlantic Meridional Overturning Circulation under extreme atmospheric CO2 conditions

    Directory of Open Access Journals (Sweden)

    Rita Lecci

    2016-05-01

    Full Text Available This study investigates the climate sensitivity to a strong CO2 atmospheric forcing focusing on the North Atlantic Ocean (NA. The analysis is based on a set of 600 years long experiments performed with a state-of-the-art coupled general circulation model (CGCM with the 1990 reference value of atmospheric CO2 multiplied by 4, 8 and 16. Extreme increases in atmospheric CO2 concentration have been applied to force the climate system towards stable states with different thermo-dynamical properties and analyze how the different resulting oceanic stratification and diffusion affect the Atlantic Meridional Overturning Circulation (AMOC. The AMOC weakens in response to the induced warming with distinctive features in the extreme case: a southward shift of convective sites and the formation of a density front at mid-latitudes. The analysis of the density fluxes reveals that NA loses density at high latitudes and gains it southward of 40°N mainly due to the haline contribution. Our results indicate that the most important processes that control the AMOC are active in the high latitudes and are related to the stability of the water column. The increased ocean stratification stabilizes the ocean interior leading to a decreased vertical diffusivity, a reduction in the formation of deep water and a weaker circulation. In particular, the deep convection collapses mainly in the Labrador Sea as a consequence of the water column stratification under high latitudes freshening.

  10. Reduced interdecadal variability of Atlantic Meridional Overturning Circulation under global warming

    Science.gov (United States)

    Cheng, Jun; Liu, Zhengyu; Zhang, Shaoqing; Liu, Wei; Dong, Lina; Liu, Peng; Li, Hongli

    2016-01-01

    Interdecadal variability of the Atlantic Meridional Overturning Circulation (AMOC-IV) plays an important role in climate variation and has significant societal impacts. Past climate reconstruction indicates that AMOC-IV has likely undergone significant changes. Despite some previous studies, responses of AMOC-IV to global warming remain unclear, in particular regarding its amplitude and time scale. In this study, we analyze the responses of AMOC-IV under various scenarios of future global warming in multiple models and find that AMOC-IV becomes weaker and shorter with enhanced global warming. From the present climate condition to the strongest future warming scenario, on average, the major period of AMOC-IV is shortened from ∼50 y to ∼20 y, and the amplitude is reduced by ∼60%. These reductions in period and amplitude of AMOC-IV are suggested to be associated with increased oceanic stratification under global warming and, in turn, the speedup of oceanic baroclinic Rossby waves. PMID:26951654

  11. Manual for best practice for emergency response procedures, part 4: a checklist of best practice requirements for the prevention and management of inrushes, fires, explosions and other emergencies.

    CSIR Research Space (South Africa)

    Spencer, KC

    2000-02-01

    Full Text Available PRACTICE FOR EMERGENCY RESPONSE PROCEDURES PART 4 A CHECKLIST OF BEST PRACTICE REQUIREMENTS FOR THE PREVENTION AND MANAGEMENT OF INRUSHES, FIRES, EXPLOSIONS AND OTHER EMERGENCIES Authors: K C Spencer, D M Walters, T P T Page and A G du Plessis... CHECKLIST FOR BEST PRACTICES PAGE 1 Part 1 Prevention of inrushes, fires, explosions and other emergencies Ref. ISSUE Y/N/? ACTION 1 Control mechanism for administration of CoPs, procedures & standards. 2 Introduction of hazards...

  12. Meteorological conditions, physiochemical properties, thermal-oxygen stratification, water overturn and water balance of Lake Gardno on Wolin Island

    Directory of Open Access Journals (Sweden)

    Tylkowski Jacek

    2015-09-01

    Full Text Available The main research problem of the paper is aimed at determining the proper functioning of Lake Gardno within the period 2012-2014 considered as hydrological years in reference to the physiochemical properties of its waters, water balance, thermal regime and water overturn. Lake Gardno is a representative of non-run-off lake geo-eco-systems; it is situated within the Southern Baltic Sea Coastland at the cliff shore of Wolin Island. The paper analyses how weather conditions affect the specifics of water supplies provided to the lake and seasonal dynamics of its waters, their chemical, thermal and aerobic properties. It also specifies their overturn and balance with a particular emphasis on their supplies together with fog deposits.

  13. 4M Overturned Pyramid (MOP) Model Utilization: Case Studies on Collision in Indonesian and Japanese Maritime Traffic Systems (MTS)

    OpenAIRE

    Wanginingastuti Mutmainnah; Masao Furusho

    2016-01-01

    4M Overturned Pyramid (MOP) model is a new model, proposed by authors, to characterized MTS which is adopting epidemiological model that determines causes of accidents, including not only active failures but also latent failures and barriers. This model is still being developed. One of utilization of MOP model is characterizing accidents in MTS, i.e. collision in Indonesia and Japan that is written in this paper. The aim of this paper is to show the characteristics of ship collision accidents...

  14. Back to the future: Hormone replacement therapy as part of a prevention strategy for women at the onset of menopause.

    Science.gov (United States)

    Lobo, Roger A; Pickar, James H; Stevenson, John C; Mack, Wendy J; Hodis, Howard N

    2016-11-01

    In the late 1980s, several observational studies and meta-analyses suggested that hormone replacement therapy (HRT) was beneficial for prevention of osteoporosis, coronary heart disease, dementia and decreased all-cause mortality. In 1992, the American College of Physicians recommended HRT for prevention of coronary disease. In the late 1990s and early 2000s, several randomized trials in older women suggested coronary harm and that the risks, including breast cancer, outweighed any benefit. HRT stopped being prescribed at that time, even for women who had severe symptoms of menopause. Subsequently, reanalyzes of the randomized trial data, using age stratification, as well as newer studies, and meta-analyses have been consistent in showing that younger women, 50-59 years or within 10 years of menopause, have decreased coronary disease and all-cause mortality; and did not have the perceived risks including breast cancer. These newer findings are consistent with the older observational data. It has also been reported that many women who abruptly stopped HRT had more risks, including more osteoporotic fractures. The current data confirm a "timing" hypothesis for benefits and risks of HRT, showing that younger have many benefits and few risks, particularly if therapy is predominantly focused on the estrogen component. We discuss these findings and put into perspective the potential risks of treatment, and suggest that we may have come full circle regarding the use of HRT. In so doing we propose that HRT should be considered as part of a general prevention strategy for women at the onset of menopause. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  15. REE and Isotopic Compositions of Lunar Basalts Demonstrate Partial Melting of Hybridized Mantle Sources after Cumulate Overturn is Required

    Science.gov (United States)

    Dygert, N. J.; Liang, Y.

    2017-12-01

    Lunar basalts maintain an important record of the composition of the lunar interior. Much of our understanding of the Moon's early evolution comes from studying their petrogenesis. Recent experimental work has advanced our knowledge of major and trace element fractionation during lunar magma ocean (LMO) crystallization [e.g., 1-3], which produced heterogeneous basalt sources in the Moon's mantle. With the new experimental constraints, we can evaluate isotopic and trace element signatures in lunar basalts in unprecedented detail, refining inferences about the Moon's dynamic history. Two petrogenetic models are invoked to explain the compositions of the basalts. The assimilation model argues they formed as primitive melts of early LMO cumulates that assimilated late LMO cumulates as they migrated upward. The cumulate overturn model argues that dense LMO cumulates sank into the lunar interior, producing hybridized sources that melted to form the basalts. Here we compare predicted Ce/Yb and Hf and Nd isotopes of partial melts of LMO cumulates with measured compositions of lunar basalts to evaluate whether they could have formed by end-member petrogenetic models. LMO crystallization models suggest all LMO cumulates have chondrite normalized Ce/Yb 1.5; these could not have formed by assimilation of any LMO cumulate or residual liquid (or KREEP basalt, which has isotopically negative ɛNd and ɛHf). In contrast, basalt REE patterns and isotopes can easily be modeled assuming partial melting of hybridized mantle sources, indicating overturn may be required. A chemical requirement for overturn independently confirms that late LMO cumulates are sufficiently low in viscosity to sink into the lunar interior, as suggested by recent rock deformation experiments [4]. Overturned, low viscosity late LMO cumulates would be relatively stable around the core [5]. High Ce/Yb basalts require that overturned cumulates were mixed back into the overlying mantle by convection within a few

  16. Anomalously weak Labrador Sea convection and Atlantic overturning during the past 150 years.

    Science.gov (United States)

    Thornalley, David J R; Oppo, Delia W; Ortega, Pablo; Robson, Jon I; Brierley, Chris M; Davis, Renee; Hall, Ian R; Moffa-Sanchez, Paola; Rose, Neil L; Spooner, Peter T; Yashayaev, Igor; Keigwin, Lloyd D

    2018-04-01

    The Atlantic meridional overturning circulation (AMOC) is a system of ocean currents that has an essential role in Earth's climate, redistributing heat and influencing the carbon cycle 1, 2 . The AMOC has been shown to be weakening in recent years 1 ; this decline may reflect decadal-scale variability in convection in the Labrador Sea, but short observational datasets preclude a longer-term perspective on the modern state and variability of Labrador Sea convection and the AMOC 1, 3-5 . Here we provide several lines of palaeo-oceanographic evidence that Labrador Sea deep convection and the AMOC have been anomalously weak over the past 150 years or so (since the end of the Little Ice Age, LIA, approximately AD 1850) compared with the preceding 1,500 years. Our palaeoclimate reconstructions indicate that the transition occurred either as a predominantly abrupt shift towards the end of the LIA, or as a more gradual, continued decline over the past 150 years; this ambiguity probably arises from non-AMOC influences on the various proxies or from the different sensitivities of these proxies to individual components of the AMOC. We suggest that enhanced freshwater fluxes from the Arctic and Nordic seas towards the end of the LIA-sourced from melting glaciers and thickened sea ice that developed earlier in the LIA-weakened Labrador Sea convection and the AMOC. The lack of a subsequent recovery may have resulted from hysteresis or from twentieth-century melting of the Greenland Ice Sheet 6 . Our results suggest that recent decadal variability in Labrador Sea convection and the AMOC has occurred during an atypical, weak background state. Future work should aim to constrain the roles of internal climate variability and early anthropogenic forcing in the AMOC weakening described here.

  17. A commentary on the Atlantic meridional overturning circulation stability in climate models

    Science.gov (United States)

    Gent, Peter R.

    2018-02-01

    The stability of the Atlantic meridional overturning circulation (AMOC) in ocean models depends quite strongly on the model formulation, especially the vertical mixing, and whether it is coupled to an atmosphere model. A hysteresis loop in AMOC strength with respect to freshwater forcing has been found in several intermediate complexity climate models and in one fully coupled climate model that has very coarse resolution. Over 40% of modern climate models are in a bistable AMOC state according to the very frequently used simple stability criterion which is based solely on the sign of the AMOC freshwater transport across 33° S. In a recent freshwater hosing experiment in a climate model with an eddy-permitting ocean component, the change in the gyre freshwater transport across 33° S is larger than the AMOC freshwater transport change. This casts very strong doubt on the usefulness of this simple AMOC stability criterion. If a climate model uses large surface flux adjustments, then these adjustments can interfere with the atmosphere-ocean feedbacks, and strongly change the AMOC stability properties. AMOC can be shut off for many hundreds of years in modern fully coupled climate models if the hosing or carbon dioxide forcing is strong enough. However, in one climate model the AMOC recovers after between 1000 and 1400 years. Recent 1% increasing carbon dioxide runs and RCP8.5 future scenario runs have shown that the AMOC reduction is smaller using an eddy-resolving ocean component than in the comparable standard 1° ocean climate models.

  18. The role of Meridional Overturning Circulation (MOC) on Ancient Climates and Implications for Anthropogenic Climate Change

    Science.gov (United States)

    Cumming, M.

    2017-12-01

    Our increasingly robust history of ancient climates indicates that high latitude glaciation is the ultimate product of an episodic cooling trend that began about 100-million years ago rather than a result of a yet-to-be identified modal change. Antarctic geography (continent surrounded by ocean) allowed ice to develop prior to significant glaciation in the Northern Hemisphere (ocean surrounded by land), but global ice volume generally increased as Earth cooled. The question of what caused the Ice Ages should be reframed as to "What caused the Cenozoic Cooling?" Records tell us that changes in temperature and CO2 levels rise and fall together, however it is not clear when CO2 acts as a driver versus when it is primarily an indicator of temperature change. The episodic nature of the cooling trend suggests other more dynamic phenomena are involved. It is proposed that oceanic meridional overturning circulation (MOC) plays a significant role in regulating Earth's surface temperature. Robust MOC has a cooling effect which results from its sequestration of cold waters (together with their increased heat-absorbing potential) below the surface. Unable to better absorb equatorial insolation for great lengths of time, oceanic deep waters are not able to fully compensate for the heat lost by warm-water transport to Polar Regions. A lag-time between cooling and subsequent warming yields lower operating temperatures commensurate with the strength of global MOC. The long-term decline in global temperatures is largely explained by the tectonic reshaping of ocean basins and the connections between them such that MOC has generally, but not uniformly, increased. Geophysically Influenced MOC (GIMOC) has caused a significant proportion of the lowering of global temperatures in the Cenozoic Era. Short-term disruptions in MOC (and subsequent impacts on global temperatures) were likely involved in Late Pleistocene glacial termination events and may already be compounding present

  19. The Atlantic Meridional Overturning Circulation over time: a Nd isotope perspective

    Science.gov (United States)

    Goldstein, S. L.; Pena, L. D.; Yehudai, M.; Seguí, M. J.; Kim, J.; Knudson, K. P.; Basak, C.

    2017-12-01

    The Atlantic Meridional Overturning Circulation (AMOC) is a major means for distributing heat between the tropics and the high latitudes, and thus its temporal variability has major impacts on ice age cycles. We present a summary of work in-progress to generate north-south profiles of the AMOC from the North Atlantic to the Southern Ocean, at various time slices over the past 2 Ma, based on Nd isotopes in Fe-Mn oxide encrusted foraminifera and fish debris. Our sites show a consistent north-south gradient in the North Atlantic source water (NSW) signal strength throughout, providing strong evidence that the data represent the fluctuations of the AMOC. The North Atlantic data show strong evidence that the eNd of the NSW end-member remained similar to today through this time interval (Kim et al. this meeting). We have identified 5 modes of the AMOC circulation. The most common ones are the (1) "interglacial norm" where the NSW signal remains strong into the South Atlantic similar to the present-day, and the (2) "glacial norm" where moderate southern source water (SSW) signals extend into the deep North Atlantic. Less common are the (3) "weak AMOC" mode, typical of Heinrich events, the Mid-Pleistocene Transition (MPT), and MIS 10,16, where even the deep North Atlantic shows a strong SSW signal, and its counterpart the (4) "ultra-strong AMOC", in MIS 9, 11, 19, 21 and 25, when the NSW signal is unusually strong south of the equator. Finally, during the (5) "pre-MPT" mode, in MIS 26 and 27, uniquely low Nd isotope ratios in the North Atlantic signals major input of Nd from the Canadian Shield directly preceding the MPT AMOC crisis (Pena and Goldstein, Science 2014), reflecting events there that likely triggered it. Overall we expect that the AMOC profiles will be useful as a means to directly relate climate to concurrent ocean circulation through time.

  20. Variability of the Atlantic meridional overturning circulation in the last millennium and two IPCC scenarios

    Energy Technology Data Exchange (ETDEWEB)

    Ortega, Pablo; Montoya, Marisa; Gonzalez-Rouco, Fidel [Universidad Complutense de Madrid, Ciudad Universitaria, Dpto. Astrofisica y Ciencias de la Atmosfera/Instituto de Geociencias, Facultad de Ciencias Fisicas, Madrid (Spain); Universidad Complutense de Madrid, Ciudad Universitaria, Instituto de Geociencias (UCM-CSIC), Facultad de Ciencias Fisicas, Madrid (Spain); Mignot, Juliette [IPSL/LOCEAN, UPMC/CNRS/IRD/MNHN, Universite Pierre et Marie Curie, Paris Cedex 05 (France); Legutke, Stephanie [Deutsches Klimarechenzentrum (DKRZ), Hamburg (Germany)

    2012-05-15

    The variability of the Atlantic meridional overturning circulation (AMOC) is investigated in several climate simulations with the ECHO-G atmosphere-ocean general circulation model, including two forced integrations of the last millennium, one millennial-long control run, and two future scenario simulations of the twenty-first century. This constitutes a new framework in which the AMOC response to future climate change conditions is addressed in the context of both its past evolution and its natural variability. The main mechanisms responsible for the AMOC variability at interannual and multidecadal time scales are described. At high frequencies, the AMOC is directly responding to local changes in the Ekman transport, associated with three modes of climate variability: El Nino-Southern Oscillation (ENSO), the North Atlantic Oscillation (NAO), and the East Atlantic (EA) pattern. At low frequencies, the AMOC is largely controlled by convection activity south of Greenland. Again, the atmosphere is found to play a leading role in these variations. Positive anomalies of convection are preceded in 1 year by intensified zonal winds, associated in the forced runs to a positive NAO-like pattern. Finally, the sensitivity of the AMOC to three different forcing factors is investigated. The major impact is associated with increasing greenhouse gases, given their strong and persistent radiative forcing. Starting in the Industrial Era and continuing in the future scenarios, the AMOC experiences a final decrease of up to 40% with respect to the preindustrial average. Also, a weak but significant AMOC strengthening is found in response to the major volcanic eruptions, which produce colder and saltier surface conditions over the main convection regions. In contrast, no meaningful impact of the solar forcing on the AMOC is observed. Indeed, solar irradiance only affects convection in the Nordic Seas, with a marginal contribution to the AMOC variability in the ECHO-G runs. (orig.)

  1. Mid-Pliocene shifts in ocean overturning circulation and the onset of Quaternary-style climates

    Directory of Open Access Journals (Sweden)

    M. Sarnthein

    2009-06-01

    Full Text Available A major tipping point of Earth's history occurred during the mid-Pliocene: the onset of major Northern-Hemisphere Glaciation (NHG and of pronounced, Quaternary-style cycles of glacial-to-interglacial climates, that contrast with more uniform climates over most of the preceding Cenozoic and continue until today (Zachos et al., 2001. The severe deterioration of climate occurred in three steps between 3.2 Ma (warm MIS K3 and 2.7 Ma (glacial MIS G6/4 (Lisiecki and Raymo, 2005. Various models (sensu Driscoll and Haug, 1998 and paleoceanographic records (intercalibrated using orbital age control suggest clear linkages between the onset of NHG and the three steps in the final closure of the Central American Seaways (CAS, deduced from rising salinity differences between Caribbean and the East Pacific. Each closing event led to an enhanced North Atlantic meridional overturning circulation and this strengthened the poleward transport of salt and heat (warmings of +2–3°C (Bartoli et al., 2005. Also, the closing resulted in a slight rise in the poleward atmospheric moisture transport to northwestern Eurasia (Lunt et al., 2007, which probably led to an enhanced precipitation and fluvial run-off, lower sea surface salinity (SSS, and an increased sea-ice cover in the Arctic Ocean, hence promoting albedo and the build-up of continental ice sheets. Most important, new evidence shows that the closing of the CAS led to greater steric height of the North Pacific and thus doubled the low-saline Arctic Throughflow from the Bering Strait to the East Greenland Current (EGC. Accordingly, Labrador Sea IODP Site 1307 displays an abrupt but irreversible EGC cooling of 6°C and freshening by ~2 psu from 3.25/3.16–3.00 Ma, right after the first but still reversible attempt of closing the CAS.

  2. Prevention of non-contact anterior cruciate ligament injuries in sports. Part II: systematic review of the effectiveness of prevention programmes in male athletes.

    Science.gov (United States)

    Alentorn-Geli, Eduard; Mendiguchía, Jurdan; Samuelsson, Kristian; Musahl, Volker; Karlsson, Jon; Cugat, Ramon; Myer, Gregory D

    2014-01-01

    To synthesize the results of systematic literature review focused on the effectiveness of anterior cruciate ligament (ACL) injury prevention programmes in male athletes. All abstracts and articles of potential interest identified through the systematic literature search were reviewed in detail to determine on inclusion status. Information regarding prevention programmes to reduce ACL injuries or to modify risk factors for ACL injuries in male athletes was systematically extracted and included intervention and study design, characteristics of participants, sport and level of competition, characteristics of prevention programmes, results, and conclusions. All studies were evaluated for methodological quality to assess the risk of bias. The principal findings of this systematic review are as follows: (1) most of the studies applied prevention programmes that utilized risk factors as outcomes of interest as opposed to ACL injury incidence (5 and 2 studies, respectively); (2) the effectiveness of prevention programmes to reduce ACL injuries in male athletes is equivocal (1 in favour, 1 against) and only refers to soccer players; (3) the effectiveness of prevention programmes to modify risk factors for ACL injuries in male athletes is controversial (2 in favour, 3 against) and outcome data are limited to cutting manoeuvres. Data regarding the effectiveness of prevention programmes to reduce ACL injuries or to modify risk factors for ACL injuries in male athletes are scarce and not conclusive. Future research to better determine the most effective approaches to optimize the effectiveness of prevention programmes targeted to reduce ACL injuries in male athletes is warranted.

  3. The incidental pulmonary nodule in a child. Part 2: Commentary and suggestions for clinical management, risk communication and prevention

    Energy Technology Data Exchange (ETDEWEB)

    Westra, Sjirk J. [Massachusetts General Hospital, Division of Pediatric Radiology, Boston, MA (United States); Thacker, Paul G. [Medical University of South Carolina, Department of Radiology, Charleston, SC (United States); Podberesky, Daniel J. [Nemours Children' s Hospital, Department of Radiology, Orlando, FL (United States); Lee, Edward Y. [Boston Children' s Hospital, Department of Pediatric Radiology, Boston, MA (United States); Iyer, Ramesh S. [Seattle Children' s Hospital, Department of Radiology, Seattle, WA (United States); Hegde, Shilpa V. [Arkansas Children' s Hospital, Department of Radiology, Little Rock, AR (United States); Guillerman, R.P. [Texas Children' s Hospital, Department of Radiology, Houston, TX (United States); Mahani, Maryam Ghadimi [University of Michigan Health System, Section of Pediatric Radiology, C. S. Mott Children' s Hospital, Department of Radiology, Ann Arbor, MI (United States)

    2015-05-01

    The incidental detection of small lung nodules in children is a vexing consequence of an increased reliance on CT. We present an algorithm for the management of lung nodules detected on CT in children, based on the presence or absence of symptoms, the presence or absence of elements in the clinical history that might explain these nodules, and the imaging characteristics of the nodules (such as attenuation measurements within the nodule). We provide suggestions on how to perform a thoughtfully directed and focused search for clinically occult extrathoracic disease processes (including malignant disease) that may present as an incidentally detected lung nodule on CT. This algorithm emphasizes that because of the lack of definitive information on the natural history of small solid nodules that are truly detected incidentally, their clinical management is highly dependent on the caregivers' individual risk tolerance. In addition, we present strategies to reduce the prevalence of these incidental findings, by preventing unnecessary chest CT scans or inadvertent inclusion of portions of the lungs in scans of adjacent body parts. Application of these guidelines provides pediatric radiologists with an important opportunity to practice patient-centered and evidence-based medicine. (orig.)

  4. Chaotic variability of the meridional overturning circulation on subannual to interannual timescales

    Directory of Open Access Journals (Sweden)

    J. J.-M. Hirschi

    2013-09-01

    Full Text Available Observations and numerical simulations have shown that the meridional overturning circulation (MOC exhibits substantial variability on sub- to interannual timescales. This variability is not fully understood. In particular it is not known what fraction of the MOC variability is caused by processes such as mesoscale ocean eddies and waves which are ubiquitous in the ocean. Here we analyse twin experiments performed with a global ocean model at eddying (1/4° and non-eddying (1° resolutions. The twin experiments are forced with the same surface fluxes for the 1958 to 2001 period but start from different initial conditions. Our results show that on subannual to interannual timescales a large fraction of MOC variability directly reflects variability in the surface forcing. Nevertheless, in the eddy-permitting case there is an initial-condition-dependent MOC variability (hereinafter referred to as "chaotic" variability of several Sv (1Sv = 106 m3 s−1 in the Atlantic and the Indo-Pacific. In the Atlantic the chaotic MOC variability represents up to 30% of the total variability at the depths where the maximum MOC occurs. In comparison the chaotic MOC variability is only 5–10% in the non-eddying case. The surface forcing being almost identical in the twin experiments suggests that mesoscale ocean eddies are the most likely cause for the increased chaotic MOC variability in the eddying case. The exact formation time of eddies is determined by the initial conditions which are different in the two model passes, and as a consequence the mesoscale eddy field is decorrelated in the twin experiments. In regions where eddy activity is high in the eddy-permitting model, the correlation of sea surface height variability in the twin runs is close to zero. In the non-eddying case in contrast, we find high correlations (0.9 or higher over most regions. Looking at the sub- and interannual MOC components separately reveals that most of the chaotic MOC variability

  5. Meltwater routing and the Atlantic meridional overturning circulation: A Gulf of Mexico perspective

    Science.gov (United States)

    Flower, B. P.; Williams, C.; Randle, N.; Hastings, D. W.

    2008-12-01

    Routing of low-salinity meltwater from the Laurentide Ice Sheet (LIS) into the North Atlantic via eastern outlets (e.g., St. Lawrence and Hudson River systems) and northern outlets (e.g., Hudson Bay and Arctic Ocean) is thought to have reduced Atlantic meridional overturning circulation (AMOC) and thereby triggered rapid regional to global climate change during the last glacial cycle. In contrast, southward meltwater flow to the Gulf of Mexico is generally thought to allow enhanced AMOC and warmer climates in the North Atlantic region. Situated at the outlet of the Mississippi River system, Orca Basin is ideally located to record meltwater input from the LIS. Orca Basin core MD02-2550 collected by the R/V Marion Dufresne in 2002 on IMAGES cruise VIII allows sub-centennial-scale records of Mg/Ca sea-surface temperature (SST) and δ18Oseawater back to ca. 23.9 ka. Accumulation rates average about 40 cm/k.y. Our current data extend from ca. 16.5-7 ka, with age control provided by 40 AMS radiocarbon dates (nearly all in stratigraphic order; calibrated using Calib 5.0.2). We use paired Mg/Ca and oxygen isotope data on Globigerinoides ruber to isolate changes in the oxygen isotopic composition of seawater. Four major episodic δ18O decreases of more than 2 per mil indicate substantial LIS meltwater input. Intervals of major meltwater discharge to the Gulf of Mexico do not appear to match known pulses of global sea level increase. However, abrupt reductions in southward meltwater input to the Gulf of Mexico seem to correlate with abrupt coolings in the North Atlantic region (e.g., Younger Dryas, Intra-Allerod cold period, and Oldest Dryas). In particular, a 3.5 per mil δ18O increase centered at 10,970 radiocarbon years B.P. (the "cessation event") appears to coincide with the onset of the Younger Dryas in European lakes and with Δ14C evidence from Cariaco Basin for AMOC reduction. Furthermore, recent results with the NCAR Community Climate System model (CCSM3) indicate

  6. The accuracy of estimates of the overturning circulation from basin-wide mooring arrays

    Science.gov (United States)

    Sinha, B.; Smeed, D. A.; McCarthy, G.; Moat, B. I.; Josey, S. A.; Hirschi, J. J.-M.; Frajka-Williams, E.; Blaker, A. T.; Rayner, D.; Madec, G.

    2018-01-01

    Previous modeling and observational studies have established that it is possible to accurately monitor the Atlantic Meridional Overturning Circulation (AMOC) at 26.5°N using a coast-to-coast array of instrumented moorings supplemented by direct transport measurements in key boundary regions (the RAPID/MOCHA/WBTS Array). The main sources of observational and structural errors have been identified in a variety of individual studies. Here a unified framework for identifying and quantifying structural errors associated with the RAPID array-based AMOC estimates is established using a high-resolution (eddy resolving at low-mid latitudes, eddy permitting elsewhere) ocean general circulation model, which simulates the ocean state between 1978 and 2010. We define a virtual RAPID array in the model in close analogy to the real RAPID array and compare the AMOC estimate from the virtual array with the true model AMOC. The model analysis suggests that the RAPID method underestimates the mean AMOC by ∼1.5 Sv (1 Sv = 106 m3 s-1) at ∼900 m depth, however it captures the variability to high accuracy. We examine three major contributions to the streamfunction bias: (i) due to the assumption of a single fixed reference level for calculation of geostrophic transports, (ii) due to regions not sampled by the array and (iii) due to ageostrophic transport. A key element in (i) and (iii) is use of the model sea surface height to establish the true (or absolute) geostrophic transport. In the upper 2000 m, we find that the reference level bias is strongest and most variable in time, whereas the bias due to unsampled regions is largest below 3000 m. The ageostrophic transport is significant in the upper 1000 m but shows very little variability. The results establish, for the first time, the uncertainty of the AMOC estimate due to the combined structural errors in the measurement design and suggest ways in which the error could be reduced. Our work has applications to basin

  7. "What Controls the Structure and Stability of the Ocean Meridional Overturning Circulation: Implications for Abrupt Climate Change?"

    Energy Technology Data Exchange (ETDEWEB)

    Fedorov, Alexey [Yale University

    2013-11-23

    The central goal of this research project is to understand the properties of the ocean meridional overturning circulation (MOC) – a topic critical for understanding climate variability and stability on a variety of timescales (from decadal to centennial and longer). Specifically, we have explored various factors that control the MOC stability and decadal variability in the Atlantic and the ocean thermal structure in general, including the possibility abrupt climate change. We have also continued efforts on improving the performance of coupled ocean-atmosphere GCMs.

  8. Stagnant lids and mantle overturns: Implications for Archaean tectonics, magmagenesis, crustal growth, mantle evolution, and the start of plate tectonics

    Directory of Open Access Journals (Sweden)

    Jean H. Bédard

    2018-01-01

    Full Text Available The lower plate is the dominant agent in modern convergent margins characterized by active subduction, as negatively buoyant oceanic lithosphere sinks into the asthenosphere under its own weight. This is a strong plate-driving force because the slab-pull force is transmitted through the stiff sub-oceanic lithospheric mantle. As geological and geochemical data seem inconsistent with the existence of modern-style ridges and arcs in the Archaean, a periodically-destabilized stagnant-lid crust system is proposed instead. Stagnant-lid intervals may correspond to periods of layered mantle convection where efficient cooling was restricted to the upper mantle, perturbing Earth's heat generation/loss balance, eventually triggering mantle overturns. Archaean basalts were derived from fertile mantle in overturn upwelling zones (OUZOs, which were larger and longer-lived than post-Archaean plumes. Early cratons/continents probably formed above OUZOs as large volumes of basalt and komatiite were delivered for protracted periods, allowing basal crustal cannibalism, garnetiferous crustal restite delamination, and coupled development of continental crust and sub-continental lithospheric mantle. Periodic mixing and rehomogenization during overturns retarded development of isotopically depleted MORB (mid-ocean ridge basalt mantle. Only after the start of true subduction did sequestration of subducted slabs at the core-mantle boundary lead to the development of the depleted MORB mantle source. During Archaean mantle overturns, pre-existing continents located above OUZOs would be strongly reworked; whereas OUZO-distal continents would drift in response to mantle currents. The leading edge of drifting Archaean continents would be convergent margins characterized by terrane accretion, imbrication, subcretion and anatexis of unsubductable oceanic lithosphere. As Earth cooled and the background oceanic lithosphere became denser and stiffer, there would be an increasing

  9. Manual hyperinflation partly prevents reductions of functional residual capacity in cardiac surgical patients--a randomized controlled trial

    NARCIS (Netherlands)

    Paulus, Frederique; Veelo, Denise P.; de Nijs, Selma B.; Beenen, Ludo F. M.; Bresser, Paul; de Mol, Bas A. J. M.; Binnekade, Jan M.; Schultz, Marcus J.

    2011-01-01

    Cardiac surgery is associated with post-operative reductions of functional residual capacity (FRC). Manual hyperinflation (MH) aims to prevent airway plugging, and as such could prevent the reduction of FRC after surgery. The main purpose of this study was to determine the effect of MH on

  10. Antimicrobial commodities. part 2. Antimicrobial and odor-preventing fibers; Kokin seikatsu yohin ( 2 ). Kokin boshu sen`i

    Energy Technology Data Exchange (ETDEWEB)

    Yabe, N. [Toray Research Center Inc., Shiga (Japan)

    1998-05-01

    Demand for antimicrobial and order-preventing fibers is still expanding smoothly after a boom during a period from 1982 to 1985 owing to the great progress in its safety, manufacturing technology and evaluation of antimicrobial property. In this paper, the antimicrobial and odor-preventing fibers are described summarily. Main antimicrobial agents used in the antimicrobial and odor-preventing fibers hitherto are aromatic halogen compounds and organic silicon quaternary ammonium salts. In recent years, the kinds of antimicrobial agents are increased corresponding to the expansion of the demand for antimicrobial and odor-preventing fibers. Specifically, metals or inorganic particles containing metals; and quaternary ammonium salts or organic silicon quaternary ammonium salts are used frequently. Recently, the studies in respect to the utilization of chitin and chitosan are executed actively. Mainly employed processing method of the antimicrobial and odor-prevention fibers is a post processing by a working liquid containing kneaded fiber forming (mixed fiber forming) of antimicrobial inorganic particles such as metal powders or metal supporting zeolites; and an antimicrobial agent. 8 refs., 3 figs., 5 tabs.

  11. The GEOVIDE cruise in May–June 2014 reveals an intense Meridional Overturning Circulation over a cold and fresh subpolar North Atlantic

    Directory of Open Access Journals (Sweden)

    P. Zunino

    2017-11-01

    Full Text Available The GEOVIDE cruise was carried out in the subpolar North Atlantic (SPNA along the OVIDE section and across the Labrador Sea in May–June 2014. It was planned to clarify the distribution of the trace elements and their isotopes in the SPNA as part of the GEOTRACES international program. This paper focuses on the state of the circulation and distribution of thermohaline properties during the cruise. In terms of circulation, the comparison with the 2002–2012 mean state shows a more intense Irminger Current and also a weaker North Atlantic Current, with a transfer of volume transport from its northern to its central branch. However, those anomalies are compatible with the variability already observed along the OVIDE section in the 2000s. In terms of properties, the surface waters of the eastern SPNA were much colder and fresher than the averages over 2002–2012. In spite of negative temperature anomalies in the surface waters, the heat transport across the OVIDE section estimated at 0.56 ± 0.06 PW was the largest measured since 2002. This relatively large value is related to the relatively strong Meridional Overturning Circulation measured across the OVIDE section during GEOVIDE (18.7 ± 3.0 Sv. By analyzing the air–sea heat and freshwater fluxes over the eastern SPNA in relation to the heat and freshwater content changes observed during 2013 and 2014, we concluded that on a short timescale these changes were mainly driven by air–sea heat and freshwater fluxes rather than by ocean circulation.

  12. The GEOVIDE cruise in May-June 2014 reveals an intense Meridional Overturning Circulation over a cold and fresh subpolar North Atlantic

    Science.gov (United States)

    Zunino, Patricia; Lherminier, Pascale; Mercier, Herlé; Daniault, Nathalie; García-Ibáñez, Maribel I.; Pérez, Fiz F.

    2017-11-01

    The GEOVIDE cruise was carried out in the subpolar North Atlantic (SPNA) along the OVIDE section and across the Labrador Sea in May-June 2014. It was planned to clarify the distribution of the trace elements and their isotopes in the SPNA as part of the GEOTRACES international program. This paper focuses on the state of the circulation and distribution of thermohaline properties during the cruise. In terms of circulation, the comparison with the 2002-2012 mean state shows a more intense Irminger Current and also a weaker North Atlantic Current, with a transfer of volume transport from its northern to its central branch. However, those anomalies are compatible with the variability already observed along the OVIDE section in the 2000s. In terms of properties, the surface waters of the eastern SPNA were much colder and fresher than the averages over 2002-2012. In spite of negative temperature anomalies in the surface waters, the heat transport across the OVIDE section estimated at 0.56 ± 0.06 PW was the largest measured since 2002. This relatively large value is related to the relatively strong Meridional Overturning Circulation measured across the OVIDE section during GEOVIDE (18.7 ± 3.0 Sv). By analyzing the air-sea heat and freshwater fluxes over the eastern SPNA in relation to the heat and freshwater content changes observed during 2013 and 2014, we concluded that on a short timescale these changes were mainly driven by air-sea heat and freshwater fluxes rather than by ocean circulation.

  13. Effectiveness of programmes as part of primary prevention demonstrated on the example of cardiovascular diseases and the metabolic syndrome.

    Science.gov (United States)

    Korczak, Dieter; Dietl, Markus; Steinhauser, Gerlinde

    2011-04-01

    The HTA-report (HTA = Health Technology Assessment) deals with the primary prevention of cardiovascular diseases and diabetes mellitus type 2. In 2009 approximately 356,000 people died in Germany due to cardiovascular diseases. According to estimations about 6.3 million people are suffering from diabetes mellitus type 2. The interventions that are subsidized by the public health insurance are mainly focused on sufficient physical activities, healthy nutrition, stress management and the reduction of the consumption of addictive drugs and luxury food. Which lifestyle-related measures and/or programmes for primary prevention of cardiovascular diseases and of the metabolic syndrome are effective? To what extent will the health status be improved by these offers? To what extent will existing health resources and skills be strengthened by these offers? Are there any differences regarding the effectiveness among the interventions with respect to different settings or subgroups? Which lifestyle-related interventions and/or programmes for primary prevention of cardiovascular diseases and of the metabolic syndrome are sustainable and cost-effective? Which outcome parameters are in the view of the contributors decisive for the evaluation of the effectiveness? In the view of the contributor are there different values between the outcome parameters? In the view of the payers and other actors are there different values between the outcome parameters? Which ethical and juridical factors have to be considered? Which social and/or socio-economic parameters influence the use of the services and effectiveness? A systematic literature research is done in 35 databases. For the period 2005 to 2010, reviews, epidemiological and clinical studies as well as economical evaluations which deal with primary prevention programmes regarding cardiovascular diseases or the metabolic syndrome are included. 44 publications meet the inclusion criteria. These studies confirm the effectiveness of the

  14. Effectiveness of programmes as part of primary prevention demonstrated on the example of cardiovascular diseases and the metabolic syndrome

    Directory of Open Access Journals (Sweden)

    Korczak, Dieter

    2011-01-01

    Full Text Available Background: The HTA-report (HTA = Health Technology Assessment deals with the primary prevention of cardiovascular diseases and diabetes mellitus type 2. In 2009 approximately 356,000 people died in Germany due to cardiovascular diseases. According to estimations about 6.3 million people are suffering from diabetes mellitus type 2. The interventions that are subsidized by the public health insurance are mainly focused on sufficient physical activities, healthy nutrition, stress management and the reduction of the consumption of addictive drugs and luxury food. Objectives: Which lifestyle-related measures and/or programmes for primary prevention of cardiovascular diseases and of the metabolic syndrome are effective? To what extent will the health status be improved by these offers? To what extent will existing health resources and skills be strengthened by these offers? Are there any differences regarding the effectiveness among the interventions with respect to different settings or subgroups? Which lifestyle-related interventions and/or programmes for primary prevention of cardiovascular diseases and of the metabolic syndrome are sustainable and cost-effective? Which outcome parameters are in the view of the contributors decisive for the evaluation of the effectiveness? In the view of the contributor are there different values between the outcome parameters? In the view of the payers and other actors are there different values between the outcome parameters? Which ethical and juridical factors have to be considered? Which social and/or socio-economic parameters influence the use of the services and effectiveness? Methods: A systematic literature research is done in 35 databases. For the period 2005 to 2010, reviews, epidemiological and clinical studies as well as economical evaluations which deal with primary prevention programmes regarding cardiovascular diseases or the metabolic syndrome are included. Results: 44 publications meet the

  15. New insights on diabetes mellitus and obesity in Africa-Part 2: prevention, screening and economic burden.

    Science.gov (United States)

    Kengne, Andre Pascal; Sobngwi, Eugene; Echouffo-Tcheugui, Justin-Basile; Mbanya, Jean-Claude

    2013-08-01

    Evidence has been accumulating on the importance of the rising burden of diabetes mellitus on the African continent at an increasingly higher pace. In the first paper of this series of two companion papers, recent evidence on the prevalence, pathogenesis and comorbidities of obesity and diabetes mellitus in Africa were summarised. In this second paper, we focus on recent developments pertaining to the prevention, screening and the economic burden of diabetes and obesity on the continent. There are indications that awareness on diabetes and chronic diseases at large has increased in Africa in recent times. However, the care for diabetes largely remains suboptimal in most countries, which are not adequately prepared to face the prevention and control of diabetes, as the costs of caring for the condition pose a tremendous challenge to most local economies. Moreover, translation strategies to prevent and control diabetes and obesity, on the continent, are still to be evaluated.

  16. 4M Overturned Pyramid (MOP Model Utilization: Case Studies on Collision in Indonesian and Japanese Maritime Traffic Systems (MTS

    Directory of Open Access Journals (Sweden)

    Wanginingastuti Mutmainnah

    2016-07-01

    Full Text Available 4M Overturned Pyramid (MOP model is a new model, proposed by authors, to characterized MTS which is adopting epidemiological model that determines causes of accidents, including not only active failures but also latent failures and barriers. This model is still being developed. One of utilization of MOP model is characterizing accidents in MTS, i.e. collision in Indonesia and Japan that is written in this paper. The aim of this paper is to show the characteristics of ship collision accidents that occur both in Indonesian and Japanese maritime traffic systems. There were 22 collision cases in 2008–2012 (8 cases in Indonesia and 14 cases in Japan. The characteristics presented in this paper show failure events at every stage of the three accident development stages (the beginning of an accident, the accident itself, and the evacuation process.

  17. Changes of deep Pacific overturning circulation and carbonate chemistry during middle Miocene East Antarctic ice sheet expansion

    Science.gov (United States)

    Ma, Xiaolin; Tian, Jun; Ma, Wentao; Li, Ke; Yu, Jimin

    2018-02-01

    East Antarctic ice sheet expansion (EAIE) at ∼13.9 Ma in the middle Miocene represents a major climatic event during the long-term Cenozoic cooling, but ocean circulation and carbon cycle changes during this event remain unclear. Here, we present new fish teeth isotope (εNd) and benthic foraminiferal B/Ca records from the South China Sea (SCS), newly integrated meridional Pacific benthic foraminiferal δ18O and δ13C records and simulated results from a biogeochemical box model to explore the responses of deep Pacific Ocean circulation and carbon cycle across EAIE. The εNd and meridional benthic δ13C records reveal a more isolated Pacific Deep Water (PDW) and a sluggish Pacific meridional overturning circulation during the post-EAIE with respect to the pre-EAIE owing to weakened southern-sourced deep water formation. The deep-water [CO23-] and calcium carbonate mass accumulation rate in the SCS display markedly similar increases followed by recoveries to the pre-EAIE level during EAIE, which were probably caused by a shelf-basin shift of CaCO3 deposition and strengthened weathering due to a sea level fall within EAIE. The model results show that the ∼1‰ positive δ13C excursion during EAIE could be attributed to increased weathering of high-δ13C shelf carbonates and a terrestrial carbon reservoir expansion. The drawdown of atmospheric CO2 over the middle Miocene were probably caused by combined effects of increased shelf carbonate weathering, expanded land biosphere carbon storage and a sluggish deep Pacific meridional overturning circulation.

  18. Early Intervention and Maltreated Children: A Current Look at the Child Abuse Prevention and Treatment Act and Part C

    Science.gov (United States)

    Moxley, Kathleen M.; Squires, Jane; Lindstrom, Lauren

    2012-01-01

    Current literature regarding the prevalence of child abuse and neglect, resulting developmental impacts on children, and early intervention services for children and families involved in the child welfare system is summarized. While early intervention eligibility referrals are mandated for this population under the Child Abuse Prevention and…

  19. Family Medicine in a Consumer Age — Part 4: Preventive Medicine, Professional Satisfaction, and the Rise of Consumerism

    Science.gov (United States)

    Warner, Morton M.

    1977-01-01

    In an attempt to find out if the physician perceives the same strengths and weaknesses in today's practice of family medicine as does the consumer, the Lay Advisory Committee of the College's B.C. Chapter initiated a survey of physicians' and consumers' attitudes. This article, the fourth and last in a series, presents some of the results of the survey as they relate to preventive-medicine, professional satisfaction and the rise of consumerism.

  20. A survey of practice patterns and the health promotion and prevention attitudes of US chiropractors. Maintenance care: part I.

    Science.gov (United States)

    Rupert, R L

    2000-01-01

    To investigate the primary care, health promotion activities associated with what has historically been called "maintenance care" (MC) as used in the practice of chiropractic in the United States. This includes issues such as investigating the purpose of MC, what conditions and patient populations it best serves, how frequently it is required, what therapeutic interventions constitute MC, how often it is recommended, and what percent of patient visits are for prevention and health promotion services. It also investigates the economic impact of these services. Postal survey of a randomized sample of practicing US chiropractors. The questionnaire was structured with a 5-point ordinal Likert scale (28 questions) and brief fill-in questionnaire (12 questions). The 40-question survey was mailed to 1500 chiropractors selected at random from a pool of chiropractors with active practices in the United States. The National Directory of Chiropractic database was the source of actively practicing chiropractors from which doctor selection was made. The sample was derived by using the last numbers composing the zip codes assigned by the US Postal Service. This sampling method assured potential inclusion of chiropractors from all 50 states, from rural areas and large cities, and assured a sample weighting based on population density that might not have been afforded by a simple random sample. Six hundred and fifty-eight (44%) of the questionnaires were completed and returned. US chiropractors agreed or strongly agreed that the purpose of MC was to optimize health (90%), prevent conditions from developing (88%), provide palliative care (86%), and minimize recurrence or exacerbations (95%). MC was viewed as helpful in preventing both musculoskeletal and visceral health problems. There was strong agreement that the therapeutic composition of MC placed virtually equal weight on exercise (96%) and adjustments/manipulation (97%) and that other interventions, including dietary

  1. On-line vibration and loose parts monitoring of nuclear power stations as a preventive maintenance tool

    International Nuclear Information System (INIS)

    An equipment for on-line monitoring of vibrations and loose parts of nuclear power plants is described. The unit consists of piezoelectric transducers, preamplifiers, a data processor, and peripherals. It secures on-line measurement without interfering with the operation of the power plant. A diagram is given showing the monitor of vibrations and loose parts for pressurized water reactors and the Spectra-Scan equipment for the automatic recording and computer processing of noise signals is described. A survey is given of diagnostic methods for internal vibrations, noise and oscillations and procedures for the analysis of recordings are described. The experiences of Atomica International with the observation of vibrations in nuclear power plants are described and an economic assessment is presented of the efficiency of on-line monitoring of these vibrations. A cost-benefit analysis is made of such equipment which justifies their introduction. (B.S.)

  2. Effect of sporadic destratification, seasonal overturn, and artificial mixing on CH4 emissions from a subtropical hydroelectric reservoir

    Science.gov (United States)

    Guérin, Frédéric; Deshmukh, Chandrashekhar; Labat, David; Pighini, Sylvie; Vongkhamsao, Axay; Guédant, Pierre; Rode, Wanidaporn; Godon, Arnaud; Chanudet, Vincent; Descloux, Stéphane; Serça, Dominique

    2016-06-01

    Inland waters in general and freshwater reservoirs specifically are recognized as a source of CH4 into the atmosphere. Although the diffusion at the air-water interface is the most studied pathway, its spatial and temporal variations are poorly documented. We measured temperature and O2 and CH4 concentrations every 2 weeks for 3.5 years at nine stations in a subtropical monomictic reservoir which was flooded in 2008 (Nam Theun 2 Reservoir, Lao PDR). Based on these results, we quantified CH4 storage in the water column and diffusive fluxes from June 2009 to December 2012. We compared diffusive emissions with ebullition from Deshmukh et al. (2014) and aerobic methane oxidation and downstream emissions from Deshmukh et al. (2016). In this monomictic reservoir, the seasonal variations of CH4 concentration and storage were highly dependent on the thermal stratification. Hypolimnic CH4 concentration and CH4 storage reached their maximum in the warm dry season (WD) when the reservoir was stratified. Concentration and storage decreased during the warm wet (WW) season and reached its minimum after the reservoir overturned in the cool dry (CD) season. The sharp decreases in CH4 storage were concomitant with extreme diffusive fluxes (up to 200 mmol m-2 d-1). These sporadic emissions occurred mostly in the inflow region in the WW season and during overturn in the CD season in the area of the reservoir that has the highest CH4 storage. Although they corresponded to less than 10 % of the observations, these extreme CH4 emissions (> 5 mmol m-2 d-1) contributed up to 50 % of total annual emissions by diffusion. During the transition between the WD and WW seasons, a new emission hotspot was identified upstream of the water intake where diffusive fluxes peaked at 600 mmol m-2 d-1 in 2010 down to 200 mmol m-2 d-1 in 2012. The hotspot was attributed to the mixing induced by the water intakes (artificial mixing). Emissions from this area contributed 15-25 % to total annual emissions

  3. Discussing Firearm Ownership and Access as Part of Suicide Risk Assessment and Prevention: "Means Safety" versus "Means Restriction".

    Science.gov (United States)

    Stanley, Ian H; Hom, Melanie A; Rogers, Megan L; Anestis, Michael D; Joiner, Thomas E

    2017-01-01

    The goal of this study was to describe the relative utility of the terms "means safety" versus "means restriction" in counseling individuals to limit their access to firearms in the context of a mock suicide risk assessment. Overall, 370 participants were randomized to read a vignette depicting a clinical scenario in which managing firearm ownership and access was discussed either using the term "means safety" or "means restriction." Participants rated the term "means safety" as significantly more acceptable and preferable than "means restriction." Participants randomized to the "means safety" condition reported greater intentions to adhere to clinicians' recommendations to limit access to a firearm for safety purposes (F[1,367] = 7.393, p = .007, [Formula: see text]). The term "means safety" may be more advantageous than "means restriction" when discussing firearm ownership and access in clinical settings and public health-oriented suicide prevention efforts.

  4. Moving alcohol prevention research forward-Part II: new directions grounded in community-based system dynamics modeling.

    Science.gov (United States)

    Apostolopoulos, Yorghos; Lemke, Michael K; Barry, Adam E; Lich, Kristen Hassmiller

    2018-02-01

    Given the complexity of factors contributing to alcohol misuse, appropriate epistemologies and methodologies are needed to understand and intervene meaningfully. We aimed to (1) provide an overview of computational modeling methodologies, with an emphasis on system dynamics modeling; (2) explain how community-based system dynamics modeling can forge new directions in alcohol prevention research; and (3) present a primer on how to build alcohol misuse simulation models using system dynamics modeling, with an emphasis on stakeholder involvement, data sources and model validation. Throughout, we use alcohol misuse among college students in the United States as a heuristic example for demonstrating these methodologies. System dynamics modeling employs a top-down aggregate approach to understanding dynamically complex problems. Its three foundational properties-stocks, flows and feedbacks-capture non-linearity, time-delayed effects and other system characteristics. As a methodological choice, system dynamics modeling is amenable to participatory approaches; in particular, community-based system dynamics modeling has been used to build impactful models for addressing dynamically complex problems. The process of community-based system dynamics modeling consists of numerous stages: (1) creating model boundary charts, behavior-over-time-graphs and preliminary system dynamics models using group model-building techniques; (2) model formulation; (3) model calibration; (4) model testing and validation; and (5) model simulation using learning-laboratory techniques. Community-based system dynamics modeling can provide powerful tools for policy and intervention decisions that can result ultimately in sustainable changes in research and action in alcohol misuse prevention. © 2017 Society for the Study of Addiction.

  5. Prevention of anterior cruciate ligament injuries in sports. Part I: systematic review of risk factors in male athletes.

    Science.gov (United States)

    Alentorn-Geli, Eduard; Mendiguchía, Jurdan; Samuelsson, Kristian; Musahl, Volker; Karlsson, Jon; Cugat, Ramon; Myer, Gregory D

    2014-01-01

    The purpose of this study was to report a comprehensive literature review on the risk factors for anterior cruciate ligament (ACL) injuries in male athletes. All abstracts were read and articles of potential interest were reviewed in detail to determine on inclusion status for systematic review. Information regarding risk factors for ACL injuries in male athletes was extracted from all included studies in systematic fashion and classified as environmental, anatomical, hormonal, neuromuscular, or biomechanical. Data extraction involved general characteristics of the included studies (type of study, characteristics of the sample, type of sport), methodological aspects (for quality assessment), and the principal results for each type of risk factor. The principal findings of this systematic review related to the risk factors for ACL injury in male athletes are: (1) most of the evidence is related to environmental and anatomical risk factors; (2) dry weather conditions may increase the risk of non-contact ACL injuries in male athletes; (3) artificial turf may increase the risk of non-contact ACL injuries in male athletes; (4) higher posterior tibial slope of the lateral tibial plateau may increase the risk of non-contact ACL injuries in male athletes. Anterior cruciate ligament injury in male athletes likely has a multi-factorial aetiology. There is a lack of evidence regarding neuromuscular and biomechanical risk factors for ACL injury in male athletes. Future research in male populations is warranted to provide adequate prevention strategies aimed to decrease the risk of this serious injury in these populations.

  6. Intra-articular Implantation of Mesenchymal Stem Cells, Part 1: A Review of the Literature for Prevention of Postmeniscectomy Osteoarthritis.

    Science.gov (United States)

    Kraeutler, Matthew J; Mitchell, Justin J; Chahla, Jorge; McCarty, Eric C; Pascual-Garrido, Cecilia

    2017-01-01

    Osteoarthritis (OA) after a partial or total meniscectomy procedure is a common pathology. Because of the high incidence of meniscectomy in the general population, as well as the significant burden of knee OA, there is increasing interest in determining methods for delaying postmeniscectomy OA. Biological therapies, including mesenchymal stem cells (MSCs), induced pluripotent stem cells (iPSCs), and platelet-rich plasma (PRP), have been proposed as possible therapies that could delay OA in this and other settings. Several studies in various animal models have evaluated the effect of injecting MSCs into the knee joints of animals with OA induced either by meniscal excision with or without anterior cruciate ligament transection. When compared with control groups receiving injections without progenitor cells, short-term benefits in the experimental groups have been reported. In human subjects, there are limited data to determine the effect of biological therapies for use in delaying or preventing the onset of OA after a meniscectomy procedure. The purpose of this review is to highlight the findings in the presently available literature on the use of intra-articular implantation of MSCs postmeniscectomy and to offer suggestions for future research with the goal of delaying or treating early OA postmeniscectomy with MSCs.

  7. How does Atlantic Multi-decadal Overturning Circulation modulate Tropical circulation and preciptation responses to global warming ?

    Science.gov (United States)

    Vial, Jessica; Codron, Francis; Cassou, Christophe; Bony, Sandrine

    2017-04-01

    Tropical precipitation response to global warming remains highly uncertain. Most of the uncertainty is attributed to inter-model spread in atmospheric circulation changes. Model diversity in tropical circulation response has been traced further to differences in Tropical surface warming patterns, and in particular to the location of the maximum increase in the Equatorial Pacific. The involved mechanisms point to the importance of ocean-atmosphere interactions assessed through several process metrics. Here, we investigate the role of the Atlantic Multi-decadal Overturning Circulation (AMOC) in the response of the Tropical circulation to increased greenhouse gazes concentration. AMOC has been shown to affect the global Tropics, including the Equatorial surface warming pattern through atmospheric bridges across Central and/or North America. We use two ensembles of the coupled (ocean-atmosphere) CNRM-CM5 climate model that differ from their mean AMOC and apply an abrupt doubling CO2 concentration in both cases. Beyond the modulation role of AMOC in the Tropical circulation and precipitation changes, we show that AMOC has a potential effect on the estimation of the climate sensitivity of the model.

  8. Sensitivity of North Atlantic subpolar gyre and overturning to stratification-dependent mixing: response to global warming

    Energy Technology Data Exchange (ETDEWEB)

    Marzeion, Ben [Massachusetts Institute of Technology, EAPS, Cambridge, MA (United States); Nansen Environmental and Remote Sensing Center and Bjerknes Centre for Climate Research, Bergen (Norway); University of Innsbruck, Tropical Glaciology Group, Institute of Geography, Innsbruck (Austria); Levermann, Anders [Potsdam University, Earth System Analysis, Potsdam Institute for Climate Impact Research and Institute of Physics, Potsdam (Germany); Mignot, Juliette [Universite Pierre et Marie Curie, LOCEAN, Paris (France)

    2010-04-15

    We use a reduced complexity climate model with a three-dimensional ocean component and realistic topography to investigate the effect of stratification-dependent mixing on the sensitivity of the North Atlantic subpolar gyre (SPG), and the Atlantic meridional overturning circulation (AMOC), to idealized CO{sub 2} increase and peaking scenarios. The vertical diffusivity of the ocean interior is parameterized as {kappa} {proportional_to} N {sup -{alpha}}, where N is the local buoyancy frequency. For all parameter values 0 {<=} {alpha} {<=} 3, we find the SPG, and subsequently the AMOC, to weaken in response to increasing CO{sub 2} concentrations. The weakening is significantly stronger for {alpha} {>=} {alpha}{sub cr} {approx} 1.5. Depending on the value of {alpha}, two separate model states develop. These states remain different after the CO{sub 2} concentration is stabilized, and in some cases even after the CO{sub 2} concentration has been decreased again to the pre-industrial level. This behaviour is explained by a positive feedback between stratification and mixing anomalies in the Nordic Seas, causing a persistent weakening of the SPG. (orig.)

  9. Increased Drake Passage through-flow triggered abrupt re-invigoration of Atlantic Overturning Circulation during the last deglaciation

    Science.gov (United States)

    Roberts, J.; McCave, I. N. N.; McClymont, E.; Kender, S.; Hillenbrand, C. D.; Matano, R. P.; Hodell, D. A.; Peck, V. L.

    2016-12-01

    The position of Antarctic Circumpolar Current (ACC) fronts in the Drake Passage is important for the supply of low-density intermediate water into the Atlantic, and is thus key to the stability of Atlantic Meridional Overturning Circulation (AMOC). We examined changes in the position of ACC fronts by reconstructing flow speed and temperature in the Drake Passage over the last 25,000 years. A dramatic convergence of flow speeds and temperatures at the entrance and exit of Drake Passage 14,700 years ago indicates a significant southward shift of the sub-Antarctic Front from a position north of Drake Passage. The timing of this southward shift coincides with an abrupt re-invigoration of AMOC at the onset of the Bølling-Allerød. We argue that 14,700 years ago, a southward shift in the position of the ACC fronts relative to Drake Passage enabled low-density intermediate water to enter the Atlantic; this accentuated the meridional density gradient in the Atlantic causing an abrupt re-invigoration of AMOC.

  10. Impact of the GeoMIP G1 sunshade geoengineering experiment on the Atlantic meridional overturning circulation

    Science.gov (United States)

    Hong, Yu; Moore, John C.; Jevrejeva, Svetlana; Ji, Duoying; Phipps, Steven J.; Lenton, Andrew; Tilmes, Simone; Watanabe, Shingo; Zhao, Liyun

    2017-03-01

    We analyze the multi-earth system model responses of ocean temperatures and the Atlantic Meridional Overturning Circulation (AMOC) under an idealized solar radiation management scenario (G1) from the Geoengineering Model Intercomparison Project. All models simulate warming of the northern North Atlantic relative to no geoengineering, despite geoengineering substantially offsetting the increases in mean global ocean temperatures. Increases in the temperature of the North Atlantic Ocean at the surface (˜0.25 K) and at a depth of 500 m (˜0.10 K) are mainly due to a 10 Wm-2 reduction of total heat flux from ocean to atmosphere. Although the AMOC is slightly reduced under the solar dimming scenario, G1, relative to piControl, it is about 37% stronger than under abrupt4 × CO2 . The reduction of the AMOC under G1 is mainly a response to the heat flux change at the northern North Atlantic rather than to changes in the water flux and the wind stress. The AMOC transfers heat from tropics to high latitudes, helping to warm the high latitudes, and its strength is maintained under solar dimming rather than weakened by greenhouse gas forcing acting alone. Hence the relative reduction in high latitude ocean temperatures provided by solar radiation geoengineering, would tend to be counteracted by the correspondingly active AMOC circulation which furthermore transports warm surface waters towards the Greenland ice sheet, warming Arctic sea ice and permafrost.

  11. Protective phenotypes of club cells and alveolar macrophages are favored as part of endotoxin-mediated prevention of asthma

    Science.gov (United States)

    García, Luciana N; Leimgruber, Carolina; Uribe Echevarría, Elisa M; Acosta, Patricio L; Brahamian, Jorge M; Polack, Fernando P; Miró, María S; Quintar, Amado A; Sotomayor, Claudia E

    2014-01-01

    Atopic asthma is a chronic allergic disease that involves T-helper type 2 (Th2)-inflammation and airway remodeling. Bronchiolar club cells (CC) and alveolar macrophages (AM) are sentinel cells of airway barrier against inhaled injuries, where allergy induces mucous metaplasia of CC and the alternative activation of AM, which compromise host defense mechanisms and amplify Th2-inflammation. As there is evidence that high levels of environmental endotoxin modulates asthma, the goal of this study was to evaluate if the activation of local host defenses by Lipopolysaccharide (LPS) previous to allergy development can contribute to preserving CC and AM protective phenotypes. Endotoxin stimulus before allergen exposition reduced hallmarks of allergic inflammation including eosinophil influx, Interleukin-4 and airway hyperreactivity, while the T-helper type 1 related cytokines IL-12 and Interferon-γ were enhanced. This response was accompanied by the preservation of the normal CC phenotype and the anti-allergic proteins Club Cell Secretory Protein (CCSP) and Surfactant-D, thereby leading to lower levels of CC metaplasia and preventing the increase of the pro-Th2 cytokine Thymic stromal lymphopoietin. In addition, classically activated alveolar macrophages expressing nitric oxide were promoted over the alternatively activated ones that expressed arginase-1. We verified that LPS induced a long-term overexpression of CCSP and the innate immune markers Toll-like receptor 4, and Tumor Necrosis Factor-α, changes that were preserved in spite of the allergen challenge. These results demonstrate that LPS pre-exposition modifies the local bronchioalveolar microenvironment by inducing natural anti-allergic mechanisms while reducing local factors that drive Th2 type responses, thus modulating allergic inflammation. PMID:25504013

  12. The timing hypothesis and hormone replacement therapy: a paradigm shift in the primary prevention of coronary heart disease in women. Part 2: comparative risks.

    Science.gov (United States)

    Hodis, Howard N; Mack, Wendy J

    2013-06-01

    A major misperception concerning postmenopausal hormone replacement therapy (HRT) is that the associated risks are large in magnitude and unique to HRT, but over the past 10 years, sufficient data have accumulated so that the magnitude and perspective of risks associated with the primary coronary heart disease prevention therapies of statins, aspirin, and postmenopausal HRT have become more fully defined. Review of randomized controlled trials indicates that the risks of primary prevention therapies and other medications commonly used in women's health are of similar type and magnitude, with the majority of these risks categorized as rare to infrequent (risks of postmenopausal HRT are predominantly rare (risks, including breast cancer, stroke, and venous thromboembolism are common across medications and are rare, and even rarer when HRT is initiated in women younger than 60 or who are less than 10 years since menopause. In Part 1 of this series, the sex-specificity of statins and aspirin and timing of initiation of HRT as modifiers of efficacy in women were reviewed. Herein, the comparative risks of primary prevention therapies in women are discussed. © 2013, Copyright the Authors Journal compilation © 2013, The American Geriatrics Society.

  13. Southern Ocean overturning across streamlines in an eddying simulation of the Antarctic Circumpolar Current

    Directory of Open Access Journals (Sweden)

    A. M. Treguier

    2007-12-01

    Full Text Available An eddying global model is used to study the characteristics of the Antarctic Circumpolar Current (ACC in a streamline-following framework. Previous model-based estimates of the meridional circulation were calculated using zonal averages: this method leads to a counter-intuitive poleward circulation of the less dense waters, and underestimates the eddy effects. We show that on the contrary, the upper ocean circulation across streamlines agrees with the theoretical view: an equatorward mean flow partially cancelled by a poleward eddy mass flux. Two model simulations, in which the buoyancy forcing above the ACC changes from positive to negative, suggest that the relationship between the residual meridional circulation and the surface buoyancy flux is not as straightforward as assumed by the simplest theoretical models: the sign of the residual circulation cannot be inferred from the surface buoyancy forcing only. Among the other processes that likely play a part in setting the meridional circulation, our model results emphasize the complex three-dimensional structure of the ACC (probably not well accounted for in streamline-averaged, two-dimensional models and the distinct role of temperature and salinity in the definition of the density field. Heat and salt transports by the time-mean flow are important even across time-mean streamlines. Heat and salt are balanced in the ACC, the model drift being small, but the nonlinearity of the equation of state cannot be ignored in the density balance.

  14. Sediment 231Pa/230Th as a recorder of the rate of the Atlantic meridional overturning circulation: insights from a 2-D model

    Directory of Open Access Journals (Sweden)

    S. E. Allen

    2010-03-01

    Full Text Available A two dimensional scavenging model is used to investigate the patterns of sediment 231Pa/230Th generated by the Atlantic Meridional Overturning Circulation (AMOC and further advance the application of this proxy for ocean paleocirculation studies. The scavenging parameters and the geometry of the overturning circulation cell have been chosen so that the model generates meridional sections of dissolved 230Th and 231Pa consistent with published water column profiles and an additional 12 previously unpublished profiles measured in the North and Equatorial Atlantic. The processes that generate the meridional sections of dissolved and particulate 230Th, dissolved and particulate 231Pa, dissolved and particulate 231Pa/230Th, and sediment 231Pa/230Th are discussed in detail. The results indicate that the relationship between sediment 231Pa/230Th at any given site and the overturning circulation is very complex. They clearly show that constraining past changes in the strength and geometry of the AMOC requires an extensive data set and they suggest strategies to maximize information from a limited number of samples.

  15. Condom use as part of the wider HIV prevention strategy: experiences from communities in the North West Province, South Africa.

    Science.gov (United States)

    Versteeg, Marije; Murray, Montagu

    2008-07-01

    Correct and consistent condom usage remains a pivotal strategy in reaching the target set by the South African government to reduce new HIV infections by 50% in the next 5 years. Studies have found that there has been an increase in condom usage by some categories of the population, but usage has not yet reached the desired levels in order to meet the target. This article reports on the findings of a study on condom usage in eight communities in the North West Province, which was part of a wider HIV and AIDS programme evaluation commissioned by the North West Provincial Department of Health. The main aim was to assess accessibility to condoms, and knowledge, attitudes and practices around condom use by four sampled communities in the North West Province. Eight focus group discussions were held and 50 households were interviewed. The study found positive results regarding accessibility and awareness of condoms. However, this often did not lead to the desired behavioural change of using condoms in risky sexual interactions. The majority of respondents still resisted condom usage, used condoms inconsistently, or were not in a position to negotiate protected sexual intercourse. The main reasons reported for this were: reduced pleasure, perceived and real physical side-effects, myths, lack of information, status, financial reasons, distrust in the efficacy of condoms, family planning, cultural reasons, gender-related reasons and trust. Many of the barriers to consistent condom use cannot be overcome by strategies that target the individual. Interventions need to address underlying developmental factors such as the non-biological factors that increase the susceptibility of women to HIV infection. As this falls outside of the scope of the mandate of the Department of Health, various partnerships with other key role players need to be established and/or strengthened, such as with local government, non-governmental organisations and faith-based organisations.

  16. Exceptional Shift to a Weaker Atlantic Meridional Overturning Circulation at the end of the Little Ice Age

    Science.gov (United States)

    Thornalley, D. J.; Oppo, D.; Moffa Sanchez, P.; Hall, I. R.; Keigwin, L. D.; Rose, N.; Green, K.; Pallottino, F.; Ortega, P.; Robson, J.

    2016-12-01

    Several proxy and modelling studies suggest that there may have been considerable change in the operation of the Atlantic Meridional Overturning Circulation (AMOC) during the last two millennia. Yet despite its importance for regional and global climate, the recent history of the AMOC is poorly constrained and comprehensive observational records only extend back a few decades at most. Observational data suggest that the export of large volumes of sea-ice and freshwater from the Arctic during the Great Salinity Anomaly of the late 1960s to early 1970s impacted North Atlantic circulation, and perhaps the strength of the AMOC, thus raising the possibility that more extreme events may have affected the AMOC during the pre-instrumental era. We present a suite of AMOC related proxies from high resolution marine sediment cores from the North Atlantic, spanning the last 2000 years, including proxies for both deep ocean circulation and surface ocean climate. Our results suggest that there was an exceptional shift to a weaker mode of Labrador Sea Water (LSW) formation during the late 19th century, which persisted up to the present day, notwithstanding strong decadal-scale LSW production events such as during the 1990s. Using a compilation of sites that allow the sea-surface temperature fingerprint of AMOC change to be identified, we show that the shift to weaker LSW formation was accompanied by a weakening of the combined AMOC. Preliminary data suggests that this exceptional event impacted marine ecosystems in certain locations. Based on their timing, we infer that the weakening of LSW and AMOC may have been caused by the export of sea-ice and freshwater from the Arctic during the termination of the Little Ice Age (somewhat mimicking, albeit on a smaller scale, the AMOC weakening events that accompanied the last Ice Age termination). These results have significant implications for the sensitivity of the AMOC to climate forcing, and the cause of late Holocene climate events.

  17. Choosing a particular oral anticoagulant and dose for stroke prevention in individual patients with non-valvular atrial fibrillation: part 1.

    Science.gov (United States)

    Diener, Hans-Christoph; Aisenberg, James; Ansell, Jack; Atar, Dan; Breithardt, Günter; Eikelboom, John; Ezekowitz, Michael D; Granger, Christopher B; Halperin, Jonathan L; Hohnloser, Stefan H; Hylek, Elaine M; Kirchhof, Paulus; Lane, Deirdre A; Verheugt, Freek W A; Veltkamp, Roland; Lip, Gregory Y H

    2017-03-21

    Patients with atrial fibrillation (AF) have a high risk of stroke and mortality, which can be considerably reduced by oral anticoagulants (OAC). Recently, four non-vitamin-K oral anticoagulants (NOACs) were compared with warfarin in large randomized trials for the prevention of stroke and systemic embolism. Today's clinician is faced with the difficult task of selecting a suitable OAC for a patient with a particular clinical profile or a particular pattern of risk factors and concomitant diseases. We reviewed analyses of subgroups of patients from trials of vitamin K antagonists vs. NOACs for stroke prevention in AF with the aim to identify patient groups who might benefit from a particular OAC more than from another. In the first of a two-part review, we discuss the choice of NOAC for stroke prevention in the following subgroups of patients with AF: (i) stable coronary artery disease or peripheral artery disease, including percutaneous coronary intervention with stenting and triple therapy; (ii) cardioversion, ablation and anti-arrhythmic drug therapy; (iii) mechanical valves and rheumatic valve disease, (iv) patients with time in therapeutic range of >70% on warfarin; (v) patients with a single stroke risk factor (CHA2DS2VASc score of 1 in males, 2 in females); and (vi) patients with a single first episode of paroxysmal AF. Although there are no major differences in terms of efficacy and safety between the NOACs for some clinical scenarios, in others we are able to suggest that particular drugs and/or doses be prioritized for anticoagulation. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2016. For permissions please email: journals.permissions@oup.com.

  18. Garcinia kola seeds may prevent cognitive and motor dysfunctions in a type 1 diabetes mellitus rat model partly by mitigating neuroinflammation.

    Science.gov (United States)

    Seke Etet, Paul F; Farahna, Mohammed; Satti, Gwiria M H; Bushara, Yahia M; El-Tahir, Ahmed; Hamza, Muaawia A; Osman, Sayed Y; Dibia, Ambrose C; Vecchio, Lorella

    2017-04-15

    Background We reported recently that extracts of seeds of Garcinia kola, a plant with established hypoglycemic properties, prevented the loss of inflammation-sensible neuronal populations like Purkinje cells in a rat model of type 1 diabetes mellitus (T1DM). Here, we assessed G. kola extract ability to prevent the early cognitive and motor dysfunctions observed in this model. Methods Rats made diabetic by single injection of streptozotocin were treated daily with either vehicle solution (diabetic control group), insulin, or G. kola extract from the first to the 6th week post-injection. Then, cognitive and motor functions were assessed using holeboard and vertical pole behavioral tests, and animals were sacrificed. Brains were dissected out, cut, and processed for Nissl staining and immunohistochemistry. Results Hyperglycemia (209.26 %), body weight loss (-12.37 %), and T1DM-like cognitive and motor dysfunctions revealed behavioral tests in diabetic control animals were not observed in insulin and extract-treated animals. Similar, expressions of inflammation markers tumor necrosis factor (TNF), iba1 (CD68), and Glial fibrillary acidic protein (GFAP), as well as decreases of neuronal density in regions involved in cognitive and motor functions (-49.56 % motor cortex, -33.24 % medial septal nucleus, -41.8 % /-37.34 % cerebellar Purkinje /granular cell layers) were observed in diabetic controls but not in animals treated with insulin or G. kola. Conclusions Our results indicate that T1DM-like functional alterations are mediated, at least partly, by neuroinflammation and neuronal loss in this model. The prevention of the development of such alterations by early treatment with G. kola confirms the neuroprotective properties of the plant and warrant further mechanistic studies, considering the potential for human disease.

  19. Developing a Motion Comic for HIV/STD Prevention for Young People Ages 15-24, Part 2: Evaluation of a Pilot Intervention.

    Science.gov (United States)

    Willis, Leigh A; Kachur, Rachel; Castellanos, Ted J; Nichols, Kristen; Mendoza, Maria C B; Gaul, Zaneta J; Spikes, Pilgrim; Gamayo, Ashley C; Durham, Marcus D; LaPlace, Lisa; Straw, Julie; Staatz, Colleen; Buge, Hadiza; Hogben, Matthew; Robinson, Susan; Brooks, John; Sutton, Madeline Y

    2018-03-01

    In the United States, young people (ages 15-24 years) are disproportionately affected by human immunodeficiency virus (HIV) and other sexually transmitted diseases (STDs), due at least in part to inadequate or incorrect HIV/STD-related knowledge, attitudes, beliefs, and behavioral intentions (KABI). Comic book narratives are a proven method of HIV/STD prevention communication to strengthen KABI for HIV/STD prevention. Motion comics, a new type of comic media, are an engaging and low-cost means of narrative storytelling. The objective of this study was to quantitatively evaluate the effectiveness of a pilot six-episode HIV/STD-focused motion comic series to improve HIV/STD-related KABI among young people. We assessed change in HIV/STD knowledge, HIV stigma, condom attitudes, HIV/STD testing attitudes, and behavioral intentions among 138 participants in 15 focus groups immediately before and after viewing the motion comic series. We used paired t-tests and indicators of overall improvement to assess differences between surveys. We found a significant decrease in HIV stigma (p STD-related KABI of young adult viewers by reducing HIV stigma and increasing behavioral intentions to engage in safer sex. Our results demonstrate the promise of this novel intervention and support its use to deliver health messages to young people.

  20. Glacial climate sensitivity to different states of the Atlantic Meridional Overturning Circulation: results from the IPSL model

    Directory of Open Access Journals (Sweden)

    M. Kageyama

    2009-09-01

    Full Text Available Paleorecords from distant locations on the globe show rapid and large amplitude climate variations during the last glacial period. Here we study the global climatic response to different states of the Atlantic Meridional Overturning Circulation (AMOC as a potential explanation for these climate variations and their possible connections. We analyse three glacial simulations obtained with an atmosphere-ocean coupled general circulation model and characterised by different AMOC strengths (18, 15 and 2 Sv resulting from successive ~0.1 Sv freshwater perturbations in the North Atlantic. These AMOC states suggest the existence of a freshwater threshold for which the AMOC collapses. A weak (18 to 15 Sv AMOC decrease results in a North Atlantic and European cooling. This cooling is not homogeneous, with even a slight warming over the Norwegian Sea. Convection in this area is active in both experiments, but surprisingly stronger in the 15 Sv simulation, which appears to be related to interactions with the atmospheric circulation and sea-ice cover. Far from the North Atlantic, the climatic response is not significant. The climate differences for an AMOC collapse (15 to 2 Sv are much larger and of global extent. The timing of the climate response to this AMOC collapse suggests teleconnection mechanisms. Our analyses focus on the North Atlantic and surrounding regions, the tropical Atlantic and the Indian monsoon region. The North Atlantic cooling associated with the AMOC collapse induces a cyclonic atmospheric circulation anomaly centred over this region, which modulates the eastward advection of cold air over the Eurasian continent. This can explain why the cooling is not as strong over western Europe as over the North Atlantic. In the Tropics, the southward shift of the Inter-Tropical Convergence Zone appears to be strongest over the Atlantic and Eastern Pacific and results from an adjustment of the atmospheric and oceanic heat transports. Finally, the

  1. High Resolution Model Development to Quantify the Impact of Icebergs on the Stability of the Atlantic Meridional Overturning Circulation

    Energy Technology Data Exchange (ETDEWEB)

    Condron, Alan [Univ. of Massachusetts, Amherst, MA (United States)

    2016-10-18

    In the present-day North Atlantic Ocean, relatively warm and salty water moves northwards from the tropics to the high latitudes, sinks, and returns southward towards the equator as North Atlantic Deep Water, forming the so called Atlantic Meridional Overturning Circulation (AMOC). It has been found that the stability of the AMOC is non-linearly related to the freshwater budget of the North Atlantic. In this way, additional fresh water can be added to the ocean with little impact, until a tipping point is reached that causes the AMOC to suddenly weaken and the Northern Hemisphere to abruptly cool. A great deal of uncertainty still remains over the sensitivity of the AMOC to changes in freshwater discharge as a result of the unrealistic manner in which freshwater has historically been added to climate models. Frequently, freshwater is discharged in ocean models entirely as liquid water, but in reality a large fraction of freshwater entering the ocean is ice calving from marine glaciers (half for Antarctica and two-thirds for Greenland). To more accurately quantify AMOC sensitivity to past and future changes in freshwater input, this project developed a comprehensive iceberg model to more realistically simulate the interaction between the cryosphere and the oceans at high-latitudes. The iceberg model created is written in Fortran90 and designed to scale efficiently on High Performance Computing (HPC) clusters so that tens-of-thousands of icebergs can be simulated at any time. Experiments performed with our model showed that in the Pleistocene there would have been enormous floods of freshwater released into the North Atlantic that would have transported icebergs and meltwater along the entire east coast of the United States, as far south as Florida Keys. In addition, high-resolution, modern-day, model simulations showed that if the Greenland Ice Sheet continues to melt at its current rate then there will be a 6-fold increase in the number of icebergs drifting in the

  2. Hosed vs. unhosed: interruptions of the Atlantic Meridional Overturning Circulation in a global coupled model, with and without freshwater forcing

    Science.gov (United States)

    Brown, Nicolas; Galbraith, Eric D.

    2016-08-01

    It is well known that glacial periods were punctuated by abrupt climate changes, with large impacts on air temperature, precipitation, and ocean circulation across the globe. However, the long-held idea that freshwater forcing, caused by massive iceberg discharges, was the driving force behind these changes has been questioned in recent years. This throws into doubt the abundant literature on modelling abrupt climate change through "hosing" experiments, whereby the Atlantic Meridional Overturning Circulation (AMOC) is interrupted by an injection of freshwater to the North Atlantic: if some, or all, abrupt climate change was not driven by freshwater input, could its character have been very different than the typical hosed experiments? Here, we describe spontaneous, unhosed oscillations in AMOC strength that occur in a global coupled ocean-atmosphere model when integrated under a particular background climate state. We compare these unhosed oscillations to hosed oscillations under a range of background climate states in order to examine how the global imprint of AMOC variations depends on whether or not they result from external freshwater input. Our comparison includes surface air temperature, precipitation, dissolved oxygen concentrations in the intermediate-depth ocean, and marine export production. The results show that the background climate state has a significant impact on the character of the freshwater-forced AMOC interruptions in this model, with particularly marked variations in tropical precipitation and in the North Pacific circulation. Despite these differences, the first-order patterns of response to AMOC interruptions are quite consistent among all simulations, implying that the ocean-sea ice-atmosphere dynamics associated with an AMOC weakening dominate the global response, regardless of whether or not freshwater input is the cause. Nonetheless, freshwater addition leads to a more complete shutdown of the AMOC than occurs in the unhosed oscillations

  3. Combined effects of global warming and an Atlantic meridional overturning circulation shutdown on West African and European climate

    Science.gov (United States)

    Brown, M. G.; Vizy, E. K.; Cook, K. H.

    2011-12-01

    We investigate the effects of an Atlantic meridional overturning circulation (AMOC) shutdown, for example, due to an influx of fresh water from Arctic ice sheet melting, in combination with global warming (Intergovernmental Panel on Climate Change's A2 business as normal emissions scenario) on West African and European climate. Shutdown of the AMOC by the end of this century is generally seen as possible but not likely, but Arctic ice is melting more quickly than predicted by global models, and the consequences for climate may be severe and the changes abrupt. A regional climate model with 90-km grid spacing is used to conduct a series of present day and future AMOC shutdown simulations. The present-day control initial surface and lateral boundary conditions are derived from the present day National Center for Environmental Prediction reanalysis 2 (NCEP2). For the future runs we use coupled atmosphere-ocean GCM anomalies generated from the Intergovernmental Panel on Climate Change's Assessment Report 4 (IPCC AR4) A2 business as normal emission scenario experiment and apply them directly to the present day control boundary conditions. An idealized SSTA is derived and applied to the present day SSTs based upon coupled atmosphere/ocean GCM water hosing experiments that force a shutdown of the AMOC, but placed in the context of under global warming, In both the boreal spring and summer months, cooling in the eastern Atlantic due to the AMOC shutdown causes an eastward extension of the North Atlantic subtropical high over Europe and rainfall rates decrease markedly throughout most of Europe. In May and June, rainfall rates decrease by 50-80% over Sahelian Africa as a secondary response to the eastern Atlantic cool SSTs, as dry air is advected southward, associated with enhanced northerly flow. In contrast, the atmospheric response to the SSTA in the North Atlantic over Europe and West Africa is decoupled during the boreal summer months; rainfall over Europe continues to

  4. Community Mobilisation and Empowerment Interventions as Part of HIV Prevention for Female Sex Workers in Southern India: A Cost-Effectiveness Analysis

    Science.gov (United States)

    Vassall, Anna; Chandrashekar, Sudhashree; Pickles, Michael; Beattie, Tara S.; Shetty, Govindraj; Bhattacharjee, Parinita; Boily, Marie-Claude; Vickerman, Peter; Bradley, Janet; Alary, Michel; Moses, Stephen; Watts, Charlotte

    2014-01-01

    Background Most HIV prevention for female sex workers (FSWs) focuses on individual behaviour change involving peer educators, condom promotion and the provision of sexual health services. However, there is a growing recognition of the need to address broader societal, contextual and structural factors contributing to FSW risk behaviour. We assess the cost-effectiveness of adding community mobilisation (CM) and empowerment interventions (eg. community mobilisation, community involvement in programme management and services, violence reduction, and addressing legal policies and police practices), to core HIV prevention services delivered as part of Avahan in two districts (Bellary and Belgaum) of Karnataka state, Southern India. Methods An ingredients approach was used to estimate economic costs in US$ 2011 from an HIV programme perspective of CM and empowerment interventions over a seven year period (2004–2011). Incremental impact, in terms of HIV infections averted, was estimated using a two-stage process. An ‘exposure analysis’ explored whether exposure to CM was associated with FSW’s empowerment, risk behaviours and HIV/STI prevalence. Pathway analyses were then used to estimate the extent to which behaviour change may be attributable to CM and to inform a dynamic HIV transmission model. Findings The incremental costs of CM and empowerment were US$ 307,711 in Belgaum and US$ 592,903 in Bellary over seven years (2004–2011). Over a 7-year period (2004–2011) the mean (standard deviation, sd.) number of HIV infections averted through CM and empowerment is estimated to be 1257 (308) in Belgaum and 2775 (1260) in Bellary. This translates in a mean (sd.) incremental cost per disability adjusted life year (DALY) averted of US$ 14.12 (3.68) in Belgaum and US$ 13.48 (6.80) for Bellary - well below the World Health Organisation recommended willingness to pay threshold for India. When savings from ART are taken into account, investments in CM and empowerment are

  5. Modeling spatial and temporal variations in temperature and salinity during stratification and overturn in Dexter Pit Lake, Tuscarora, Nevada, USA

    International Nuclear Information System (INIS)

    Balistrieri, Laurie S.; Tempel, Regina N.; Stillings, Lisa L.; Shevenell, Lisa A.

    2006-01-01

    stirring, convective overturn, shear, and eddy diffusion). Inputs to the model include the size and shape of the lake, daily meteorological data (short wave radiation, long wave radiation or cloud cover, air temperature, vapor pressure, wind speed, and rainfall), rates for water inputs and outputs, the composition of inflowing water, and initial profiles of temperature and salinity. Predicted temperature profiles, which are influenced by seasonal changes in the magnitude of solar radiation, are in good agreement with observations and show the development of a strong thermocline in the summer, erosion of the thermocline during early fall, and turnover in late fall. Predicted salinity profiles are in reasonable agreement with observations and are affected by the hydrologic balance, particularly inflow of surface and groundwater and, to a lesser degree, evaporation. Defining the hydrodynamics model for Dexter pit lake is the first step in using a coupled physical - biogeochemical model (Dynamic Reservoir Simulation Model-Computational Aquatic Ecosystem Dynamics Model or DYRESM-CAEDYM) to predict the behavior of non-conservative elements (e.g., dissolved O 2 , Mn, and Fe) and their effect on water quality in this system

  6. Abrupt changes in Antarctic Intermediate Water strength lead Atlantic Meridional Overturning Circulation changes during the last deglacial

    Science.gov (United States)

    Xie, R.; Marcantonio, F.; Schmidt, M. W.

    2011-12-01

    Reorganization of meridional overturning circulation that is a response to or a trigger of climate change in the North Atlantic has been a subject of intense interest. During the last deglaciation, cold periods such as the Younger Dryas (YD) and Heinrich 1 (H1) are thought to be coincident with significant reductions in North Atlantic Deep Water (NADW) formation. Yet, the role that Antarctic Intermediate Water (AAIW) played during these cold events is still poorly constrained. Benthic Cd/Ca data from sediment cores in the Florida Straits suggest a reduced contribution of AAIW in the North Atlantic western boundary current during the YD [1]. However, ɛNd evidence in sediment cores from Tobago basin suggests a greater influence of AAIW in the North Atlantic during YD and H1 [2]. In this study, we measure ɛNd values in the authigenic Fe-Mn oxyhydroxide fraction of sediment from three cores, KNR166-2-26JPC (24°19.62'N, 83°15.14'W; 546 m) and KNR166-2-31JPC (24°13.18'N, 83°17.75'W; 751 m) within the Florida Straits, and VM12-107 (11.33°N, 66.63°W; 1079 m) in the Southern Carribean Sea. All three cores lie within the path of AAIW and are, therefore, useful to gauge the waxing and waning of AAIW during the last deglaciation. Cores 26JPC and 31JPC are located within the Florida Current, which under modern conditions represents a mixture of recirculated North Atlantic subtropical gyre water and Southern origin waters. Our preliminary results from 26JPC and 31JPC show significantly less radiogenic ɛNd values during the YD and H1 than during the Holocene (~1 epsilon unit for 26JPC and ~0.6 epsilon units for 31JPC during both periods). We interpret the lower ɛNd during the YD and H1 as signifying a decreased input of Southern-sourced waters (i.e., AAIW) arriving at these sites, in agreement with the study of Came et al.[1], but not that of Pahnke et al. in the Tobago Basin [2]. We suggest that ɛNd values in the latter study, in which the core site location is at a

  7. The onset of modern-like Atlantic meridional overturning circulation at the Eocene-Oligocene transition: Evidence, causes, and possible implications for global cooling

    Science.gov (United States)

    Abelson, Meir; Erez, Jonathan

    2017-06-01

    A compilation of benthic δ18O from the whole Atlantic and the Southern Ocean (Atlantic sector) shows two major jumps in the interbasinal gradient of δ18O (Δδ18O) during the Eocene and the Oligocene: one at ˜40 Ma and the second concomitant with the isotopic event of the Eocene-Oligocene transition (EOT), ˜33.7 Ma ago. From previously published circulation models and proxies, we show that the first Δδ18O jump reflects the thermal isolation of Antarctica associated with the proto-Antarctic circumpolar current (ACC). The second marks the onset of interhemispheric northern-sourced circulation cell, similar to the modern Atlantic meridional overturning circulation (AMOC). The onset of AMOC-like circulation slightly preceded (100-300 kyr) the EOT, as we show by the high-resolution profiles of δ18O and δ13C previously published from DSDP/ODP sites in the Southern Ocean and South Atlantic. These events coincide with the onset of antiestuarine circulation between the Nordic seas and the North Atlantic which started around the EOT and may be connected to the deepening of the Greenland-Scotland Ridge. We suggest that while the shallow proto-ACC supplied the energy for deep ocean convection in the Southern Hemisphere, the onset of the interhemispheric northern circulation cell was due to the significant EOT intensification of deepwater formation in the North Atlantic driven by the Nordic antiestuarine circulation. This onset of the interhemispheric northern-sourced circulation cell could have prompted the EOT global cooling.Plain Language SummaryThe Eocene-Oligocene transition is the major abrupt climatic event during the Cenozoic, which marks the major step to the icehouse world. We show that this transition is a shift to a world with Atlantic meridional overturning circulation (AMOC) and slightly preceded this transition. Thus, possibly was a major factor in this climatic shift.

  8. Dietary prevention of allergic diseases in infants and small children. Part II. Evaluation of methods in allergy prevention studies and sensitization markers. Definitions and diagnostic criteria of allergic diseases

    DEFF Research Database (Denmark)

    Muraro, Antonella; Dreborg, Sten; Halken, Susanne

    2004-01-01

    The role of primary prevention of allergic disease has been a matter of debate for the last 40 years. In order to shed some light into this issue a group of experts of the Section of Pediatrics EAACI critically reviewed the existing literature on the subject. The design of observational and inter......The role of primary prevention of allergic disease has been a matter of debate for the last 40 years. In order to shed some light into this issue a group of experts of the Section of Pediatrics EAACI critically reviewed the existing literature on the subject. The design of observational...

  9. Prevention of non-contact anterior cruciate ligament injuries in soccer players. Part 2: a review of prevention programs aimed to modify risk factors and to reduce injury rates.

    Science.gov (United States)

    Alentorn-Geli, Eduard; Myer, Gregory D; Silvers, Holly J; Samitier, Gonzalo; Romero, Daniel; Lázaro-Haro, Cristina; Cugat, Ramón

    2009-08-01

    Soccer is the most commonly played sport in the world, with an estimated 265 million active soccer players participating in the game as on 2006. Inherent to this sport is the higher risk of injury to the anterior cruciate ligament (ACL) relative to other sports. ACL injury causes a significant loss of time from competition in soccer, which has served as the strong impetus to conduct research that focuses to determine the risk factors for injury, and more importantly, to identify and teach techniques to reduce this injury in the sport. This research emphasis has afforded a rapid influx of literature aimed to report the effects of neuromuscular training on the risk factors and the incidence of non-contact ACL injury in high-risk soccer populations. The purpose of the current review is to sequence the most recent literature relating the effects of prevention programs that were developed to alter risk factors associated with non-contact ACL injuries and to reduce the rate of non-contact ACL injuries in soccer players. To date there is no standardized intervention program established for soccer to prevent non-contact ACL injuries. Multi-component programs show better results than single-component preventive programs to reduce the risk and incidence of non-contact ACL injuries in soccer players. Lower extremity plyometrics, dynamic balance and strength, stretching, body awareness and decision-making, and targeted core and trunk control appear to be successful training components to reduce non-contact ACL injury risk factors (decrease landing forces, decrease varus/valgus moments, and increase effective muscle activation) and prevent non-contact ACL injuries in soccer players, especially in female athletes. Pre-season injury prevention combined with an in-season maintenance program may be advocated to prevent injury. Compliance may in fact be the limiting factor to the overall success of ACL injury interventions targeted to soccer players regardless of gender. Thus

  10. Choosing a particular oral anticoagulant and dose for stroke prevention in individual patients with non-valvular atrial fibrillation: part 1

    NARCIS (Netherlands)

    Diener, H.C.; Aisenberg, J.; Ansell, J.; Atar, D.; Breithardt, G.; Eikelboom, J.; Ezekowitz, M.D.; Granger, C.B.; Halperin, J.L.; Hohnloser, S.H.; Hylek, E.M.; Kirchhof, P.; Lane, D.A.; Verheugt, F.W.A.; Veltkamp, R.; Lip, G.Y.

    2017-01-01

    Patients with atrial fibrillation (AF) have a high risk of stroke and mortality, which can be considerably reduced by oral anticoagulants (OAC). Recently, four non-vitamin-K oral anticoagulants (NOACs) were compared with warfarin in large randomized trials for the prevention of stroke and systemic

  11. Guidelines of Care for the Management of Atopic Dermatitis Part 4: Prevention of Disease Flares and Use of Adjunctive Therapies and Approaches

    Science.gov (United States)

    Sidbury, Robert; Tom, Wynnis L.; Bergman, James N.; Cooper, Kevin D.; Silverman, Robert A.; Berger, Timothy G.; Chamlin, Sarah L.; Cohen, David E.; Cordoro, Kelly M.; Davis, Dawn M.; Feldman, Steven R.; Hanifin, Jon M.; Krol, Alfons; Margolis, David J.; Paller, Amy S.; Schwarzenberger, Kathryn; Simpson, Eric L.; Williams, Hywel C.; Elmets, Craig A.; Block, Julie; Harrod, Christopher G.; Begolka, Wendy Smith; Eichenfield, Lawrence F.

    2015-01-01

    Atopic dermatitis (AD) is a common, chronic inflammatory dermatosis that can affect all age groups. This evidence-based guideline addresses important clinical questions that arise in its management. In this final section, treatments for flare prevention and adjunctive and complementary therapies and approaches are reviewed. Suggestions on utilization are given based on available evidence. PMID:25264237

  12. Minimal intervention dentistry: part 3. Paediatric dental care--prevention and management protocols using caries risk assessment for infants and young children.

    Science.gov (United States)

    Ramos-Gomez, F J; Crystal, Y O; Domejean, S; Featherstone, J D B

    2012-11-01

    Recent increases in caries prevalence in young children throughout the world highlight the need for a simple but effective infant oral care programme. This programme needs to include a medical disease prevention management model with an early establishment of a dental home and a treatment approach based on individual patient risk. This article presents an updated approach with practical forms and tools based on the principles of caries management by risk assessment, CAMBRA. This method will aid the general practitioner to develop and maintain a comprehensive protocol adequate for infant and young children oral care visits. Perinatal oral health is vitally important in preventing early childhood caries (ECC) in young children. Providing dental treatment to expectant mothers and their young children in a 'dual parallel track' is an effective innovative strategy and an efficient practice builder. It promotes prevention rather than intervention, and this may be the best way to achieve long-lasting oral health for young patients. General dental practice can adopt easy protocols that will promote early preventive visits and anticipatory guidance/counselling rather than waiting for the need for restorative treatment.

  13. "I Learned to Accept Every Part of Myself": The Transformative Impact of a Theatre-Based Sexual Health and HIV Prevention Programme

    Science.gov (United States)

    Grewe, Mary E.; Taboada, Arianna; Dennis, Alexis; Chen, Elizabeth; Stein, Kathryn; Watson, Sable; Barrington, Clare; Lightfoot, Alexandra F.

    2015-01-01

    Theatre-based interventions have been used in health promotion with young people to address HIV and sexual health. In this study, we explored the experience of undergraduate student performers participating in a theatre-based HIV prevention and sexual health education intervention for high school students in the USA. Undergraduate students…

  14. Effect of sporadic destratification, seasonal overturn and artificial mixing on CH4 emissions at the surface of a subtropical hydroelectric reservoir (Nam Theun 2 Reservoir, Lao PDR)

    Science.gov (United States)

    Guérin, F.; Deshmukh, C.; Labat, D.; Pighini, S.; Vongkhamsao, A.; Guédant, P.; Rode, W.; Godon, A.; Chanudet, V.; Descloux, S.; Serça, D.

    2015-07-01

    Inland waters in general and specifically freshwater reservoirs are recognized as source of CH4 to the atmosphere. Although the diffusion at the air-water interface is the most studied pathway, its spatial and temporal variations are poorly documented. We measured fortnightly CH4 concentrations and physico-chemical parameters at nine stations in a subtropical monomictic reservoir which was flooded in 2008 (Nam Theun 2 Reservoir, Lao PDR). Based on these results, we quantified CH4 storage in the water column and diffusive fluxes from June 2009 to December 2012. We also compared emissions with aerobic methane oxidation calculated from Deshmukh et al. (2015). In this monomictic reservoir, the seasonal variations of CH4 concentration and storage were highly dependant of the thermal stratification. Hypolimnic CH4 concentration and CH4 storage reached their maximum in the warm dry season (WD) when the reservoir was stratified. They decreased during the warm wet (WW) season and reached its minimum after the reservoir overturned in the cool dry season (CD). The sharp decreases of the CH4 storage were concomitant with sporadic extreme diffusive fluxes (up to 200 mmol m-2 d-1). These hot moments of emissions occurred mostly in the inflow region in the WW season and during the overturn in the CD season in the area of the reservoir that has the highest CH4 storage. Although they corresponded to less than 10 % of the observations, these CH4 extreme emissions (> 5 mmol m-2 d-1) contributed up to 50 % of total annual emissions by diffusion. Based on our fortnightly monitoring, we determined that accurate estimation of the emissions can be determined from measurements made at least at a monthly frequency. During the transition between the WD and WW seasons, a new hotspot of emissions was identified upstream of the water intake where diffusive fluxes peaked at 600 mmol m-2 d-1 in 2010 down to 200 mmol m-2 d-1 in 2012. In the CD season, diffusive fluxes from this area were the

  15. Development of casting investment preventing blackening of noble metal alloys. Part 4: effect of Mg(OH)2 and Ca(OH)2 as additives.

    Science.gov (United States)

    Nakai, Akira; Ogura, Hideo

    2007-11-01

    The objective of this study was to develop a casting investment that prevents the blackening of the cast surface of noble metal alloys. Experimental investments were prepared using a gypsum-bonded investment in which a hydroxide, namely Mg(OH)2 or Ca(OH)2, was added. An Ag-Pd-Cu-Au alloy was cast into the mold made of the prepared investment. The addition of both hydroxides showed a significant effect on the color of as-cast surfaces, which was improved with increase in additive content. When Mg(OH)2 or Ca(OH)2 was added at more than 4.0 mass% to the investment, it was useful in preventing the blackening of the as-cast surfaces of an Ag-Pd-Cu-Au alloy. As for differences in the effects between Mg(OH)2 and Ca(OH)2, they were not found.

  16. Development of casting investment preventing blackening of noble metal alloys Part 2. Application of developed investment for type 4 gold alloy.

    Science.gov (United States)

    Nakai, Akira; Kakuta, Kiyoshi; Goto, Shin-ichi; Kato, Katuma; Yara, Atushi; Ogura, Hideo

    2003-09-01

    The objective of this study was to evaluate the efficacy of the developed investment for the prevention of blackening of a cast Type 4 gold and to analyze the oxides on its surface in relation to the blackening of the alloy. The experimental investments were prepared using a gypsum-bonded investment in which boron (B) or aluminum (Al) was added as a reducing agent. A Type 4 gold alloy was cast into the mold made of the prepared investment. The effect of the additives was evaluated from the color difference (deltaE*) between the as-cast surface and the polished surface of the cast specimen. B and Al were effective to prevent the blackening of a Type 4 gold alloy and the color of the as-cast surface approached that of the polished surface with increasing B and Al content. The prevention of the blackening of the gold alloy can be achieved by restraining the formation of CuO.

  17. Comprehensive preventive care assessments for adults with intellectual and developmental disabilities: Part 1: How do we know if it is happening?

    Science.gov (United States)

    Smith, Glenys; Ouellette-Kuntz, Hélène; Green, Michael

    2018-04-01

    To determine how best to measure the provision of comprehensive preventive care assessment of adults with intellectual and developmental disabilities (IDD). Cross-sectional study. Ontario. Adults with IDD between 40 and 64 years of age in 2013 and 2014. Health examination was defined using the Ontario Health Insurance Plan billing data fee code A003 (with diagnostic code 917 or 319) or fee code K131, and the Primary Care Quality Composite Score (PCQS), a measure combining 7 different screening maneuvers (lipid, glucose, breast cancer, cervical cancer, colorectal cancer, eye, and hemoglobin A 1c screening), was identified using administrative health data. A total of 28 825 adults with IDD were identified in 2013 and 2014. Overall, 12.1% of adults with IDD received a health examination; 51.2% received a high (≥ 0.6) PCQS. Male patients were more likely to have received all of their eligible screening maneuvers if they had had a health examination compared with female patients (odds ratio of 5.73 vs 3.99, respectively). Less than 60% of adults with IDD appear to be receiving comprehensive preventive care. Future studies assessing the quality of preventive care received by adults with IDD should combine health examination billing codes and the PCQS. Copyright© the College of Family Physicians of Canada.

  18. Boilers: The Basics of Preventing Air Pollution Emissions from Boilers. Part 1, Air Pollution Training Institute Self-Instructional Course SI-466.

    Science.gov (United States)

    Environmental Protection Agency, Research Triangle Park, NC. Air Pollution Training Inst.

    This workbook is part one of a self-instructional course prepared for the United States Environmental Protection Agency. The student proceeds at his own pace and when questions are asked, the answers appear on the next page. The purpose of this course is to prepare the student for the APC Training Certificate and to help him do a better job. (BT)

  19. Abrupt Climate Change and the Atlantic Meridional Overturning Circulation: sensitivity and non-linear response to Arctic/sub-Arctic freshwater pulses. Collaborative research. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Hill, Christopher [MIT (Massachusetts Inst. of Technology), Cambridge, MA (United States)

    2015-06-15

    This project investigated possible mechanisms by which melt-water pulses can induce abrupt change in the Atlantic Meridional Overturning Circulation (AMOC) magnitude. AMOC magnitude is an important ingredient in present day climate. Previous studies have hypothesized abrupt reduction in AMOC magnitude in response to influxes of glacial melt water into the North Atlantic. Notable fresh-water influxes are associated with the terminus of the last ice age. During this period large volumes of melt water accumulated behind retreating ice sheets and subsequently drained rapidly when the ice weakened sufficiently. Rapid draining of glacial lakes into the North Atlantic is a possible origin of a number of paleo-record abrupt climate shifts. These include the Younger-Dryas cooling event and the 8,200 year cooling event. The studies undertaken focused on whether the mechanistic sequence by which glacial melt-water impacts AMOC, which then impacts Northern Hemisphere global mean surface temperature, is dynamically plausible. The work has implications for better understanding past climate stability. The work also has relevance for today’s environment, in which high-latitude ice melting in Greenland appears to be driving fresh water outflows at an accelerating pace.

  20. Cost-effectiveness of a cardiovascular disease primary prevention programme in a primary health care setting. Results of the Polish part of the EUROACTION project.

    Science.gov (United States)

    Sović, Nevena; Pająk, Andrzej; Jankowski, Piotr; Duenas, Alejandra; Kawecka-Jaszcz, Kalina; Wolfshaut-Wolak, Renata; Stepaniak, Urszula; Kawalec, Paweł

    2013-01-01

    Well designed cardiovascular disease (CVD) prevention programmes appear to be generally applicable and effective in reducing exposure to risk factors and the incidence of disease. However, introducing them broadly into clinical practice would have a significant impact on the healthcare budget, and requires careful consideration. The purpose of this health economic analysis was to assess the potential cost-effectiveness of the model nurse-led, comprehensive CVD primary prevention programme which was prepared and introduced in the EUROACTION project, in high-risk patients in Poland. A Markov model was developed to assess the long-term costs of preventive intervention. The health states modelled were: event-free (all patients at the beginning of observation), stable angina first year, acute myocardial infarction, stable angina subsequent year, myocardial infarction subsequent year, CVD death, and other causes of death. Health benefits from the reduction in risk factors were estimated based on Framingham risk function assuming the probability of defined health states according to British registers. The time horizon of the analysis was ten years, and one Markov cycle length was one year. The analysis was prepared from the healthcare payer's perspective. A willingness to pay threshold of three gross domestic product (GDP) per capita / quality-adjusted life years (QALY) was used. Univariate sensitivity analysis was conducted. Results were presented as an incremental cost-effectiveness ratio (ICER) expressed as an incremental cost per QALY. In Poland, EUROACTION intervention resulted mainly in reductions in the prevalence of smoking (by 14%) and high blood pressure (by 7%). Intervention on other risk factors, including blood lipids, was found to be less effective. Estimated ICERs were 19,524 PLN for men and 82,262 PLN for women. The programme was even more cost-effective in smokers i.e. estimated ICERs were 12,377 PLN in men and 53,471 PLN in women. The results were most

  1. Virtual Breakthrough Series, Part 1: Preventing Catheter-Associated Urinary Tract Infection and Hospital-Acquired Pressure Ulcers in the Veterans Health Administration.

    Science.gov (United States)

    Zubkoff, Lisa; Neily, Julia; King, Beth J; Dellefield, Mary Ellen; Krein, Sarah; Young-Xu, Yinong; Boar, Shoshana; Mills, Peter D

    2016-11-01

    In 2014 the Veterans Health Administration (VHA) of the Department of Veterans Affairs (VA) implemented a Virtual Breakthrough Series (VBTS) collaborative to help VHA facilities prevent hospital-acquired conditions: catheter-associated urinary tract infection (CAUTI) and hospital-acquired pressure ulcers (HAPUs). During the prework phase, participating facilities assembled a multidisciplinary team, assessed their current system for CAUTI or HAPU prevention, and examined baseline data to set improvement aims. The action phase consisted of educational conference calls, coaching, and monthly team reports. Learning was conducted via phone, web-based options, and e-mail. The CAUTI bundle focused on four key principles: (1) avoidance of indwelling urinary catheters, (2) proper insertion technique, (3) proper catheter maintenance, and (4) timely removal of the indwelling catheter. The HAPU bundle focused on assessment and inspection, pressure-relieving surfaces, turning and repositioning, incontinence management, and nutrition/hydration assessment and intervention. For the 18 participating units, the mean aggregated CAUTI rate decreased from 2.37 during the prework phase to 1.06 per 1,000 catheter-days during the action (implementation) phase (p model for implementing a virtual model for improvement. Copyright 2016 The Joint Commission.

  2. Utilization of Ayurveda in health care: an approach for prevention, health promotion, and treatment of disease. Part 1--Ayurveda, the science of life.

    Science.gov (United States)

    Sharma, Hari; Chandola, H M; Singh, Gurdip; Basisht, Gopal

    2007-11-01

    Ayurveda is a natural health care system that originated in India more than 5000 years ago. Its main objective is to achieve optimal health and well-being through a comprehensive approach that addresses mind, body, behavior, and environment. Ayurveda emphasizes prevention and health promotion, and provides treatment for disease. It considers the development of consciousness to be essential for optimal health and meditation as the main technique for achieving this. Treatment of disease is highly individualized and depends on the psychophysiologic constitution of the patient. There are different dietary and lifestyle recommendations for each season of the year. Common spices are utilized in treatment, as well as herbs and herbal mixtures, and special preparations known as Rasayanas are used for rejuvenation, promotion of longevity, and slowing of the aging process. A group of purification procedures known as Panchakarma removes toxins from the physiology. Whereas Western allopathic medicine is excellent in handling acute medical crises, Ayurveda demonstrates an ability to manage chronic disorders that Western medicine has been unable to. It may be projected from Ayurveda's comprehensive approach, emphasis on prevention, and ability to manage chronic disorders that its widespread use would improve the health status of the world's population.

  3. Development of casting investment preventing blackening of noble metal alloys part 1. Application of developed investment for Ag-Pd-Cu-Au alloy.

    Science.gov (United States)

    Kakuta, Kiyoshi; Nakai, Akira; Goto, Shin-ichi; Wakamatsu, Yasushi; Yara, Atushi; Miyagawa, Yukio; Ogura, Hideo

    2003-03-01

    The objective of this study is to develop a casting investment that prevents the blackening of the cast surface of noble metal alloys. The experimental investments were prepared using a gypsum-bonded investment in which the metallic powders such as boron (B), silicon (Si), aluminum (Al) and titanium (Ti) were added as oxidizing agents. An Ag-Pd-Cu-Au alloy was cast into the mold made of the prepared investment. The effect of the addition of each metal powder was evaluated from the color difference between the as-cast surface and the polished surface of the cast specimen. The color of the as-cast surface approached that of the polished surface with increasing B and Al content. A lower mean value in the color difference was obtained at 0.25-1.00 mass% B content. B and Al are useful as an additive in a gypsum-bonded investment to prevent the blackening of an Ag-Pd-Cu-Au alloy. The effects of Si and Ti powder addition could not be found.

  4. Community participation for malaria elimination in Tafea Province, Vanuatu: Part I. Maintaining motivation for prevention practices in the context of disappearing disease

    Directory of Open Access Journals (Sweden)

    Riley Ian

    2010-04-01

    Full Text Available Abstract Background In the 1990s, the experience of eliminating malaria from Aneityum Island, Vanuatu is often given as evidence for the potential to eliminate malaria in the south-west Pacific. This experience, however, cannot provide a blueprint for larger islands that represent more complex social and environmental contexts. Community support was a key contributor to success in Aneityum. In the context of disappearing disease, obtaining and maintaining community participation in strategies to eliminate malaria in the rest of Tafea Province, Vanuatu will be significantly more challenging. Method Nine focus group discussions (FGDs, 12 key informant interviews (KIIs, three transect walks and seven participatory workshops were carried out in three villages across Tanna Island to investigate community perceptions and practices relating to malaria prevention (particularly relating to bed nets; influences on these practices including how malaria is contextualized within community health and disease priorities; and effective avenues for channelling health information. Results The primary protection method identified by participants was the use of bed nets, however, the frequency and motivation for their use differed between study villages on the basis of the perceived presence of malaria. Village, household and personal cleanliness were identified by participants as important for protection against malaria. Barriers and influences on bed net use included cultural beliefs and practices, travel, gender roles, seasonality of mosquito nuisance and risk perception. Health care workers and church leaders were reported to have greatest influence on malaria prevention practices. Participants preferred receiving health information through visiting community health promotion teams, health workers, church leaders and village chiefs. Conclusion In low malaria transmission settings, a package for augmenting social capital and sustaining community participation

  5. Short-term thermal stratification and partial overturning events in a warm polymictic reservoir: effects on distribution of phytoplankton community

    Directory of Open Access Journals (Sweden)

    RM. Santos

    Full Text Available In lentic freshwater ecosystems, patterns of thermal stratification play a considerable part in determining the population dynamics of phytoplankton. In this study we investigated how these thermal patterns and the associated hydrodynamic processes affect the vertical distribution of phytoplankton during two consecutive diel cycles in a warm polymictic urban reservoir in the metropolitan region of São Paulo, Brazil. Water samples were taken and physical, chemical and biological data collected at half-meter intervals of depth along a water column at a fixed site, every 3 hours throughout the 48-hour period. Two events of stratification, followed by deepening of the thermocline occurred during the study period and led to changes in the vertical distribution of phytoplankton populations. Aphanocapsa delicatissima Nägeli was the single dominant species throughout the 48-hour period. In the second diel cycle, the density gradient induced by temperature differences avoided the sedimentation of Mougeotia sp. C. Agardh to the deepest layers. On the other hand, Pseudanabaena galeata Böcher remained in the 4.0-5.5 m deep layer. The thermal structure of the water was directly affected by two meteorological factors: air temperature and wind speed. Changes in the cell density and vertical distribution of the phytoplankton were controlled by the thermal and hydrodynamic events.

  6. Prevención indirecta de caries en la temprana infancia: Área “Aballí”. II Parte Indirect prevention of dental caries in early childhood.: “Aballí” Area. II Part

    Directory of Open Access Journals (Sweden)

    Estela Gispert Abreu

    2006-12-01

    Full Text Available Se realizó un estudio en 159 niños de 6 meses a 1 año de edad con el objetivo de analizar la influencia de la prevención indirecta en la incidencia bienal de caries en la primera infancia y la relación entre la afectación por caries y el grado de infección por Estreptococos mutans. Se formaron 2 grupos por el método aleatorio: T donde sus madres y familias convivientes con alta infección por E. mutans (Em recibieron barniz laca flúor al 2 % + clorhexidina al 1 % cada 3 meses, así como actividades educativas y curativas; y el grupo C que solo recibió estas 2 últimas actividades. Cuando los niños arribaron a los 3 años fueron examinados y se observó que la incidencia de caries dependió de forma significativa (X²=pA study was conducted among 159 children aged 6 months old -1 year old to analyse the influence of indirect prevention on the biennial incidence of dental caries in early childhood, and the relation between the affectation due to caries and the degree of infection caused by Streptococcus mutans. They were divided into groups at random: group T where their mothers and relatives living together with high E. mutans infection received fluorine shellac-varnish 2 % plus chlorhexidine 1 % every 3 months, in addition to educative and curative activities, and group C that participated only in the last two activities. The children were examined at the age of 3 and it was observed that the incidence of dental caries depended significantly (X²=p<0,001 y (t=p<0,001 on the E. mutans infection degree in the relatives, mainly in mothers, as well as on the treatment applied to them.

  7. Developing a Motion Comic for HIV/STD Prevention for Young People Ages 15-24, Part 1: Listening to Your Target Audience.

    Science.gov (United States)

    Willis, Leigh A; Kachur, Rachel; Castellanos, Ted J; Spikes, Pilgrim; Gaul, Zaneta J; Gamayo, Ashley C; Durham, Marcus; Jones, Sandra; Nichols, Kristen; Han Barthelemy, Solange; LaPlace, Lisa; Staatz, Colleen; Hogben, Matthew; Robinson, Susan; Brooks, John T; Sutton, Madeline Y

    2018-02-01

    Young people (15-24 years) in the United States are disproportionately affected by infection with human immunodeficiency virus (HIV) and sexually transmitted diseases (STD). Shortfalls in HIV/STD-related knowledge, attitudes, beliefs, and behavioral intentions (KABI) likely contribute to this discrepancy. In this report we describe our experience developing a novel means of health communication combining entertainment-education theory and recent technological advances to create a HIV/STD-focused "motion comic." We also report the audience satisfaction and acceptance of the intervention. We used the Health Belief Model (HBM), entertainment-education (EE) principles, and the Sabido Method (SM) and conducted three rounds of focus groups to develop a 38-minute HIV/STD focused motion comic for young people between the ages 15 and 24 years. Participants indicated that motion comics were an acceptable method of delivering HIV/STD prevention messages. They also expressed satisfaction with motion comics plot, story settings, the tone of humor, and drama. Our results suggest that motion comics are a viable new method of delivering health communication messages about HIV/STD and other public health issues, and warrant further development and broader evaluation.

  8. Development of casting investment preventing blackening of noble metal alloys part 3. Effect of reducing agent addition on the strength and expansion of the investments.

    Science.gov (United States)

    Meng, Yukun; Nakai, Akira; Ogura, Hideo

    2004-06-01

    Different reducing agents (B, Al, Si and Ti) were individually added to two gypsum-bonded investments to prepare investments preventing surface blackening of some noble cast alloys. The effect of different additive contents on green-body and burnout compressive strength, setting and thermal expansion of the investments were evaluated. The strength and expansion of the investments were changed by the additives. The compressive strength of Al-, Si- and Ti-added investments decreased with the increase of additive contents. The burnout strength of B-added investments significantly increased while green-body strength remained unchanged. The setting expansion of the B-added investments increased while those of the Al-, Si- and Ti-added investments decreased with the increase of additive contents. The thermal expansion of the Si- and Ti-added investments decreased, and that of the Al- and B-added investments remained unchanged. Further study is necessary to evaluate the effects of these additives on the accuracy of dental castings.

  9. The Imperial College Cambridge Manchester (ICCAM) platform study: An experimental medicine platform for evaluating new drugs for relapse prevention in addiction. Part A: Study description.

    Science.gov (United States)

    Paterson, Louise M; Flechais, Remy S A; Murphy, Anna; Reed, Laurence J; Abbott, Sanja; Boyapati, Venkataramana; Elliott, Rebecca; Erritzoe, David; Ersche, Karen D; Faluyi, Yetunde; Faravelli, Luca; Fernandez-Egea, Emilio; Kalk, Nicola J; Kuchibatla, Shankar S; McGonigle, John; Metastasio, Antonio; Mick, Inge; Nestor, Liam; Orban, Csaba; Passetti, Filippo; Rabiner, Eugenii A; Smith, Dana G; Suckling, John; Tait, Roger; Taylor, Eleanor M; Waldman, Adam D; Robbins, Trevor W; Deakin, J F William; Nutt, David J; Lingford-Hughes, Anne R

    2015-09-01

    Drug and alcohol dependence are global problems with substantial societal costs. There are few treatments for relapse prevention and therefore a pressing need for further study of brain mechanisms underpinning relapse circuitry. The Imperial College Cambridge Manchester (ICCAM) platform study is an experimental medicine approach to this problem: using functional magnetic resonance imaging (fMRI) techniques and selective pharmacological tools, it aims to explore the neuropharmacology of putative relapse pathways in cocaine, alcohol, opiate dependent, and healthy individuals to inform future drug development. Addiction studies typically involve small samples because of recruitment difficulties and attrition. We established the platform in three centres to assess the feasibility of a multisite approach to address these issues. Pharmacological modulation of reward, impulsivity and emotional reactivity were investigated in a monetary incentive delay task, an inhibitory control task, and an evocative images task, using selective antagonists for µ-opioid, dopamine D3 receptor (DRD3) and neurokinin 1 (NK1) receptors (naltrexone, GSK598809, vofopitant/aprepitant), in a placebo-controlled, randomised, crossover design. In two years, 609 scans were performed, with 155 individuals scanned at baseline. Attrition was low and the majority of individuals were sufficiently motivated to complete all five sessions (n=87). We describe herein the study design, main aims, recruitment numbers, sample characteristics, and explain the test hypotheses and anticipated study outputs. © The Author(s) 2015.

  10. An optimally tuned ensemble of the "eb_go_gs" configuration of GENIE: parameter sensitivity and bifurcations in the Atlantic overturning circulation

    Directory of Open Access Journals (Sweden)

    R. Marsh

    2013-10-01

    Full Text Available The key physical parameters for the "eb_go_gs" configuration of version 2.7.4 of GENIE, an Earth system model of intermediate complexity (EMIC, are tuned using a multi-objective genetic algorithm. An ensemble of 90 parameter sets is tuned using two ocean and two atmospheric state variables as targets. These are "Pareto-optimal", representing a range of trade-offs between the four tuning targets. For the leading five parameter sets, simulations are evaluated alongside a simulation with untuned "default" parameters, comparing selected variables and diagnostics that describe the state of the atmosphere, ocean and sea ice. Further experiments are undertaken with these selected parameter sets to compare equilibrium climate sensitivities and transient climate responses. The pattern of warming under doubled CO2 is strongly shaped by changes in the Atlantic meridional overturning circulation (AMOC, while the pattern and rate of warming under rising CO2 is closely linked to changing sea ice extent. One of the five tuned parameter sets is identified as marginally optimal, and the objective function (error landscape is further analysed in the vicinity of the tuned values of this parameter set. "Cliffs" along some dimensions motivate closer inspection of corresponding variations in the AMOC. This reveals that bifurcations in the AMOC are highly sensitive to parameters that are not typically associated with MOC stability. Specifically, the state of the AMOC is sensitive to parameters governing the wind-driven circulation and atmospheric heat transport. For the GENIE configuration presented here, the marginally optimal parameter set is recommended for single simulations, although the leading five parameter sets may be used in ensemble mode to admit a constrained degree of parametric uncertainty in climate prediction.

  11. Interhemispheric teleconnections: Late Pliocene change in Mediterranean outflow water linked to changes in Indonesian Through-Flow and Atlantic Meridional Overturning Circulation, a review and update

    Science.gov (United States)

    Sarnthein, Michael; Grunert, Patrick; Khélifi, Nabil; Frank, Martin; Nürnberg, Dirk

    2017-07-01

    The ultimate, possibly geodynamic control and potential impact of changes in circulation activity and salt discharge of Mediterranean outflow waters (MOW) on Atlantic meridional overturning circulation have formed long-standing objectives in paleoceanography. Late Pliocene changes in the distal advection of MOW were reconstructed on orbital timescales for northeast Atlantic DSDP/ODP sites 548 and 982 off Brittany and on Rockall Plateau, supplemented by a proximal record from Site U1389 west off Gibraltar, and compared to Western Mediterranean surface and deep-water records of Alboran Sea Site 978. From 3.43 to 3.3 Ma, MOW temperatures and salinities form a prominent rise by 2-4 °C and 3 psu, induced by a preceding and coeval rise in sea surface and deep-water salinity and increased summer aridity in the Mediterranean Sea. We speculate that these changes triggered an increased MOW flow and were ultimately induced by a persistent 2.5 °C cooling of Indonesian Through-Flow waters. The temperature drop resulted from the northward drift of Australia that crossed a threshold value near 3.6-3.3 Ma and led to a large-scale cooling of the eastern subtropical Indian Ocean and in turn, to a reduction of African monsoon rains. Vice versa, we show that the distinct rise in Mediterranean salt export after 3.4 Ma induced a unique long-term rise in the formation of Upper North Atlantic Deep Water, that followed with a phase lag of 100 ky. In summary, we present evidence for an interhemispheric teleconnection of processes in the Indonesian Gateways, the Mediterranean and Labrador Seas, jointly affecting Pliocene climate.

  12. Interhemispheric teleconnections: Late Pliocene change in Mediterranean outflow water linked to changes in Indonesian Through-Flow and Atlantic Meridional Overturning Circulation, a review and update

    Science.gov (United States)

    Sarnthein, Michael; Grunert, Patrick; Khélifi, Nabil; Frank, Martin; Nürnberg, Dirk

    2018-03-01

    The ultimate, possibly geodynamic control and potential impact of changes in circulation activity and salt discharge of Mediterranean outflow waters (MOW) on Atlantic meridional overturning circulation have formed long-standing objectives in paleoceanography. Late Pliocene changes in the distal advection of MOW were reconstructed on orbital timescales for northeast Atlantic DSDP/ODP sites 548 and 982 off Brittany and on Rockall Plateau, supplemented by a proximal record from Site U1389 west off Gibraltar, and compared to Western Mediterranean surface and deep-water records of Alboran Sea Site 978. From 3.43 to 3.3 Ma, MOW temperatures and salinities form a prominent rise by 2-4 °C and 3 psu, induced by a preceding and coeval rise in sea surface and deep-water salinity and increased summer aridity in the Mediterranean Sea. We speculate that these changes triggered an increased MOW flow and were ultimately induced by a persistent 2.5 °C cooling of Indonesian Through-Flow waters. The temperature drop resulted from the northward drift of Australia that crossed a threshold value near 3.6-3.3 Ma and led to a large-scale cooling of the eastern subtropical Indian Ocean and in turn, to a reduction of African monsoon rains. Vice versa, we show that the distinct rise in Mediterranean salt export after 3.4 Ma induced a unique long-term rise in the formation of Upper North Atlantic Deep Water, that followed with a phase lag of 100 ky. In summary, we present evidence for an interhemispheric teleconnection of processes in the Indonesian Gateways, the Mediterranean and Labrador Seas, jointly affecting Pliocene climate.

  13. Prevention of non-contact anterior cruciate ligament injuries in soccer players. Part 1: Mechanisms of injury and underlying risk factors.

    Science.gov (United States)

    Alentorn-Geli, Eduard; Myer, Gregory D; Silvers, Holly J; Samitier, Gonzalo; Romero, Daniel; Lázaro-Haro, Cristina; Cugat, Ramón

    2009-07-01

    dorsiflexion of the ankle when performing sport tasks, lateral trunk displacement and hip adduction combined with increased knee abduction moments (dynamic knee valgus), and increased hip internal rotation and tibial external rotation with or without foot pronation. The identified mechanisms and risk factors for non-contact ACL injuries have been mainly studied in female soccer players; thus, further research in male players is warranted. Non-contact ACL injuries in soccer players likely has a multi-factorial etiology. The identification of those athletes at increased risk may be a salient first step before designing and implementing specific pre-season and in-season training programs aimed to modify the identified risk factors and to decrease ACL injury rates. Current evidence indicates that this crucial step to prevent ACL injury is the only option to effectively prevent the sequelae of osteoarthritis associated with this traumatic injury.

  14. Evidence of accessibility and utility of point-of-care diagnostics as an integral part of prevention of mother-to-child transmission services: systematic scoping review protocol.

    Science.gov (United States)

    Katoba, Juliet; Hangulu, Lydia; Mashamba-Thompson, Tivani Phosa

    2017-11-04

    Point-of-care (POC) testing has been shown to help improve healthcare access in resource-limited settings. However, there is paucity of evidence on accessibility of POC testing for prevention of mother-to-child transmission (PMTCT) in resource-limited settings. We propose to conduct a systematic scoping review to map the evidence on POC testing services for PMTCT. A scoping review framework, proposed by Arksey and O'Malley, will guide the study. A comprehensive literature search will be performed in the following electronic databases: PubMed, Science Direct, Cochrane Central, Google Scholar and databases within EBSCOhost (Medline and CINAHL). The primary research articles published in peer-reviewed journals and grey articles addressing our question will be included. One reviewer will conduct title screening and the results will be exported to endnote library. Two independent reviewers will perform abstract, then full article screening in parallel. The same process shall be employed to extract data from eligible studies. Data analysis will involve a narrative summary of included studies and thematic content analysis aided by NVIVO software V.11. The mixed methods assessment tool will be used to assess the quality of studies that will be included. Ethical approval is not applicable to this study. The study findings will be disseminated through publication in a peer-reviewed journal and presentations at conferences related to syphilis, HIV, PMTCT, bacterial infections and POC diagnostics. CRD42017056267. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  15. Prevalence surveys as part of a strategic plan to prevent healthcare associated infections. The experience of the University Hospital "Federico II" of Naples, Italy.

    Science.gov (United States)

    Montella, E; Triassi, M; Bellopede, R; Reis, W; Palladino, R; Di Silverio, P

    2014-01-01

    The care-associated infections (HAI) are the most serious complication associated with medical care. They are the cause of diseases for patients and economic damage to public health. The University "Federico II" of Naples decided to monitor the HAI, repeating the prevalence survey conducted earlier in 2011 in order to analyze the phenomenon of infection and to evaluate the possible correlation with risk factors. The Survey was conducted according to ECDC criteria. Considered that the study carried out in 2011 was conducted following the same methodology, to compare the results of the year 2012 the prevalence rates of both years were standardized. For the year 2012, the number of patients enrolled in the study and stratification of patients by age and sex were similar to data collected in 2011. It was very interesting to find the prevalence of HAI standardized reduced in 2012 compared to 2011. As a matter of fact, in fact, that the standardized prevalence of HAI for the year 2012 was 3.1%, one percentage point lower than in 2011 (4.4%). The practical training and direct regarded as the most appropriate approach in order to make health professionals aware in the field of health care-associated infections, as well as the system of selfcontrol peripheral for the correct application of the procedures, as well as epidemiological surveillance active, measured through rates of incidence, at the same time allow the monitoring of the phenomenon is infectious and the application of corrective measures that prevent its onset. The choice to make again an epidemiological study of prevalence with the same methodology ensures, in fact, two advantages: the comparability of the data, both at intra-company both at regional, national and international evaluation of the effectiveness of corrective actions.

  16. Psychological Care, Patient Education, Orthotics, Ergonomics and Prevention Strategies for Neck Pain: An Systematic Overview Update as Part of the ICON§ Project

    Science.gov (United States)

    Gross, Anita R.; Kaplan, Faith; Huang, Stacey; Khan, Mahweesh; Santaguida, P. Lina; Carlesso, Lisa C.; MacDermid, Joy C.; Walton, David M.; Kenardy, Justin; Söderlund, Anne; Verhagen, Arianne; Hartvigsen, Jan

    2013-01-01

    Objectives: To conduct an overview on psychological interventions, orthoses, patient education, ergonomics, and 1⁰/2⁰ neck pain prevention for adults with acute-chronic neck pain. Search Strategy: Computerized databases and grey literature were searched (2006-2012). Selection Criteria: Systematic reviews of randomized controlled trials (RCTs) on pain, function/disability, global perceived effect, quality-of-life and patient satisfaction were retrieved. Data Collection & Analysis: Two independent authors selected articles, assessed risk of bias using AMSTAR tool and extracted data. The GRADE tool was used to evaluate the body of evidence and an external panel to provide critical review. Main Results: We retrieved 30 reviews (5-9 AMSTAR score) reporting on 75 RCTs with the following moderate GRADE evidence. For acute whiplash associated disorder (WAD), an education video in emergency rooms (1RCT, 405participants] favoured pain reduction at long-term follow-up thus helping 1 in 23 people [Standard Mean Difference: -0.44(95%CI: -0.66 to -0.23)). Use of a soft collar (2RCTs, 1278participants) was not beneficial in the long-term. For chronic neck pain, a mind-body intervention (2RCTs, 1 meta-analysis, 191participants) improved short-term pain/function in 1 of 4 or 6 participants. In workers, 2-minutes of daily scapula-thoracic endurance training (1RCT, 127participants) over 10 weeks was beneficial in 1 of 4 participants. A number of psychosocial interventions, workplace interventions, collar use and self-management educational strategies were not beneficial. Reviewers' Conclusions: Moderate evidence exists for quantifying beneficial and non-beneficial effects of a limited number of interventions for acute WAD and chronic neck pain. Larger trials with more rigorous controls need to target promising interventions PMID:24133554

  17. Psychological Care, Patient Education, Orthotics, Ergonomics and Prevention Strategies for Neck Pain: An Systematic Overview Update as Part of the ICON Project.

    Science.gov (United States)

    Gross, Anita R; Kaplan, Faith; Huang, Stacey; Khan, Mahweesh; Santaguida, P Lina; Carlesso, Lisa C; Macdermid, Joy C; Walton, David M; Kenardy, Justin; Söderlund, Anne; Verhagen, Arianne; Hartvigsen, Jan

    2013-01-01

    To conduct an overview on psychological interventions, orthoses, patient education, ergonomics, and 1⁰/2⁰ neck pain prevention for adults with acute-chronic neck pain. Computerized databases and grey literature were searched (2006-2012). Systematic reviews of randomized controlled trials (RCTs) on pain, function/disability, global perceived effect, quality-of-life and patient satisfaction were retrieved. Two independent authors selected articles, assessed risk of bias using AMSTAR tool and extracted data. The GRADE tool was used to evaluate the body of evidence and an external panel to provide critical review. We retrieved 30 reviews (5-9 AMSTAR score) reporting on 75 RCTs with the following moderate GRADE evidence. For acute whiplash associated disorder (WAD), an education video in emergency rooms (1RCT, 405participants] favoured pain reduction at long-term follow-up thus helping 1 in 23 people [Standard Mean Difference: -0.44(95%CI: -0.66 to -0.23)). Use of a soft collar (2RCTs, 1278participants) was not beneficial in the long-term. For chronic neck pain, a mind-body intervention (2RCTs, 1 meta-analysis, 191participants) improved short-term pain/function in 1 of 4 or 6 participants. In workers, 2-minutes of daily scapula-thoracic endurance training (1RCT, 127participants) over 10 weeks was beneficial in 1 of 4 participants. A number of psychosocial interventions, workplace interventions, collar use and self-management educational strategies were not beneficial. Moderate evidence exists for quantifying beneficial and non-beneficial effects of a limited number of interventions for acute WAD and chronic neck pain. Larger trials with more rigorous controls need to target promising interventions.

  18. Preventive and curative effects of Apple latent spherical virus vectors harboring part of the target virus genome against potyvirus and cucumovirus infections.

    Science.gov (United States)

    Tamura, Akihiro; Kato, Takahiro; Taki, Ayano; Sone, Mikako; Satoh, Nozomi; Yamagishi, Noriko; Takahashi, Tsubasa; Ryo, Bo-Song; Natsuaki, Tomohide; Yoshikawa, Nobuyuki

    2013-11-01

    Apple latent spherical virus (ALSV)-based vectors experimentally infect a broad range of plant species without causing symptoms and can effectively induce stable virus-induced gene silencing in plants. Here, we show that pre-infection of ALSV vectors harboring part of a target viral genome (we called ALSV vector vaccines here) inhibits the multiplication and spread of the corresponding challenge viruses [Bean yellow mosaic virus, Zucchini yellow mosaic virus (ZYMV), and Cucumber mosaic virus (CMV)] by a homology-dependent resistance. Further, the plants pre-infected with an ALSV vector having genome sequences of both ZYMV and CMV were protected against double inoculation of ZYMV and CMV. More interestingly, a curative effect of an ALSV vector vaccine could also be expected in ZYMV-infected cucumber plants, because the symptoms subsided on subsequent inoculation with an ALSV vector vaccine. This may be due to the invasion of ALSV, but not ZYMV, in the shoot apical meristem of cucumber. © 2013 Elsevier Inc. All rights reserved.

  19. [Prevention, diagnosis and treatment of iatrogennic lesions of biliary tract during laparoscopic cholecystectomy. Management of papila injury after invasive endoscopy. Part 1. Prevention and diagnosis of bile duct injuries].

    Science.gov (United States)

    Sváb, J; Pesková, M; Krska, Z; Gürlich, R; Kasalický, M

    2005-04-01

    Endoscopic invasive procedures in 70th and 80th years leaded to decrease reoperations on biliary tree. Iatrogenic injury of the biliary tract have increased in incidence in the first decade with the introduction of laparoscopic cholecystectomy. Athough a number of factors have been identified with a high risk of injury ( and number of technical steps have been emphasized to avoid these injury, the incidence of the bile duct injury has reached at least double the rate observed with open cholecystectomy. Cholecystectomy is most frequently performed abdominal operation and the most serious complication associated with this procedure is accidental injury to the common bile duct (0.3-0.4%). This preventable technical error has tradicionally been thought to occur in one or more of three situations: 1. When the operator attempts to clip or ligate a bleeding cystic artery and also clips the common hepatic duct (Fig. 3a). 2. When too much traction has been exerted on the gallbladder so that the common bile duct has tented up into an albow, which was either tied off with ligature or clipped (Fig. 3b). 3. When anatomic anomalies were not recognized and the wrong structure is divided, for example, when the cystic duct winds anterior to the common bile duct and enters on the left side, or when the cystic duct joins the right hepatic duct rather than the junction of the common hepatic and the common bile ducts (Fig. 1, 2, 3cd). In anatomical incertain cases is discussed about cholangiography and cholecystocholangiography during laparoscopy cholecystectomy. Most patients sustained a bile duct injury are recognized in the weeks folloving laparoscopic cholecystectomy. Careful preoperative preparation should include control of sepsis by draining any bile collections or fistulas and komplete cholangiography. Long-term results are best achieved in specialized hepatobiliary centres performing biliary reconstruction with a Roux-Y hepaticojejunostomy. Success rates over 90% have been

  20. Choking Prevention

    Science.gov (United States)

    ... Healthy Living Healthy Living Healthy Living Nutrition Fitness Sports Oral Health Emotional Wellness Growing Healthy Sleep Safety & Prevention Safety & Prevention Safety and Prevention Immunizations At Home ...

  1. An assessment of Antarctic Circumpolar Current and Southern Ocean meridional overturning circulation during 1958-2007 in a suite of interannual CORE-II simulations

    Science.gov (United States)

    Farneti, Riccardo; Downes, Stephanie M.; Griffies, Stephen M.; Marsland, Simon J.; Behrens, Erik; Bentsen, Mats; Bi, Daohua; Biastoch, Arne; Böning, Claus; Bozec, Alexandra; Canuto, Vittorio M.; Chassignet, Eric; Danabasoglu, Gokhan; Danilov, Sergey; Diansky, Nikolay; Drange, Helge; Fogli, Pier Giuseppe; Gusev, Anatoly; Hallberg, Robert W.; Howard, Armando; Ilicak, Mehmet; Jung, Thomas; Kelley, Maxwell; Large, William G.; Leboissetier, Anthony; Long, Matthew; Lu, Jianhua; Masina, Simona; Mishra, Akhilesh; Navarra, Antonio; George Nurser, A. J.; Patara, Lavinia; Samuels, Bonita L.; Sidorenko, Dmitry; Tsujino, Hiroyuki; Uotila, Petteri; Wang, Qiang; Yeager, Steve G.

    2015-09-01

    In the framework of the second phase of the Coordinated Ocean-ice Reference Experiments (CORE-II), we present an analysis of the representation of the Antarctic Circumpolar Current (ACC) and Southern Ocean meridional overturning circulation (MOC) in a suite of seventeen global ocean-sea ice models. We focus on the mean, variability and trends of both the ACC and MOC over the 1958-2007 period, and discuss their relationship with the surface forcing. We aim to quantify the degree of eddy saturation and eddy compensation in the models participating in CORE-II, and compare our results with available observations, previous fine-resolution numerical studies and theoretical constraints. Most models show weak ACC transport sensitivity to changes in forcing during the past five decades, and they can be considered to be in an eddy saturated regime. Larger contrasts arise when considering MOC trends, with a majority of models exhibiting significant strengthening of the MOC during the late 20th and early 21st century. Only a few models show a relatively small sensitivity to forcing changes, responding with an intensified eddy-induced circulation that provides some degree of eddy compensation, while still showing considerable decadal trends. Both ACC and MOC interannual variabilities are largely controlled by the Southern Annular Mode (SAM). Based on these results, models are clustered into two groups. Models with constant or two-dimensional (horizontal) specification of the eddy-induced advection coefficient κ show larger ocean interior decadal trends, larger ACC transport decadal trends and no eddy compensation in the MOC. Eddy-permitting models or models with a three-dimensional time varying κ show smaller changes in isopycnal slopes and associated ACC trends, and partial eddy compensation. As previously argued, a constant in time or space κ is responsible for a poor representation of mesoscale eddy effects and cannot properly simulate the sensitivity of the ACC and MOC

  2. Laurentide Ice Sheet meltwater and the Atlantic meridional overturning circulation since the last glacial maximum: A view from the Gulf of Mexico

    Science.gov (United States)

    Flower, B. P.; Williams, C.; Brown, E. A.; Hastings, D. W.; Hendricks, J.; Goddard, E. A.

    2010-12-01

    The influence of ice sheet meltwater on the Atlantic meridional overturning circulation (AMOC) since the last glacial maximum represents an important issue in abrupt climate change. Comparison of Greenland and Antarctic ice core records has revealed a complex interhemispheric linkage and led to different models of ocean circulation including the “bipolar seesaw.” Meltwater input from the Laurentide Ice Sheet has been invoked as a cause of proximal sea-surface temperature (SST) and salinity change in the North Atlantic, and of regional to global climate change via its influence on the AMOC. We present published and new Mg/Ca, Ba/Ca, and δ18O data on the planktic foraminifer Globigerinoides ruber from northern Gulf of Mexico sediment cores that provide detailed records of SST, δ18O of seawater (δ18Osw), and inferred salinity for the 20-8 ka interval. Age control for Orca Basin core MD02-2550 is based on >40 AMS 14C dates on Globigerinoides ruber and documents continuous sedimentation at rates >35 cm/kyr. Early meltwater input is inferred from δ18Osw and Ba/Ca data prior to and during the Mystery Interval, consistent with a high sensitivity to solar insolation and greenhouse forcing. New bulk sediment δ18O data show major spikes reaching -5.5‰ ca. 14.6 and 12.6 ka. We speculate that these excursions represent fine carbonate sediment from Canadian Paleozoic marine carbonates, analogous to detrital carbonate in the North Atlantic which has a δ18O value of -5‰. Partial support for our hypothesis comes from SEM photomicrographs of bulk sediment from this section, which show no coccoliths or foraminifera in contrast to other intervals. The biogenic carbonate flux seems to have been greatly reduced by fine sediment input. Inferred peak meltwater flow appears to have been associated with the Bolling warming and meltwater pulse 1a. Finally, meltwater reduction at the start of the Younger Dryas supports models for a diversion to North Atlantic outlets and AMOC

  3. Preventing food allergy

    DEFF Research Database (Denmark)

    de Silva, Debra; Panesar, Sukhmeet S; Thusu, Sundeep

    2013-01-01

    The European Academy of Allergy and Clinical Immunology is developing guidelines about how to prevent and manage food allergy. As part of the guidelines development process, a systematic review is planned to examine published research about the prevention of food allergy. This systematic review...... recommendations. The aim of this systematic review will be to assess the effectiveness of approaches for the primary prevention of food allergy....

  4. Injury prevention in football

    African Journals Online (AJOL)

    and cool downs before and after training and matches, respectively. As part of injury prevention, adequate injury management and rehabilitation are essential; especially in the prevention of re-injury. Unfortunately, youth football is often disadvantaged with inadequate or unavailable sports medicine personnel and treatment ...

  5. Diabetes Part 1. Definition, Diagnosis and Prevention

    African Journals Online (AJOL)

    Skoludek_R

    Introduction. Western countries are experiencing an explosion in the prevalence of type 2 diabetes (T2DM) linked to increasing obesity and a steady year on year rise in the incidence of type 1 diabetes (T1DM) in children. However, for reasons that are not currently understood, the situation in Sub-Saharan Africa is less ...

  6. Injury Control Part 2: Strategies for Prevention

    Science.gov (United States)

    2000-01-01

    Destruction of Anti-Personnel Mines 15 9a&9b Crashworthy Fuel Systems 16 10 Parachute Landing Fall 17 11 EVA Spacewalk 18 12 Protective Gear 19 13...fire escapes ■ longer fuses on firecrackers ■ traffic-light phasing of automobiles and pedestrians at intersections ■ EVA spacewalk at night to...R. Watson (Ed.). Humana Press Inc.Totowa, NJ, 1995. 42. Huber, P. and R. Litan (Eds.). The Liability Maze : The Impact Of Liability Law on Safety

  7. RF Breakdown Prevention, Part 2 Product Overview

    Science.gov (United States)

    2015-05-07

    Aerospace Corporation Eric Holzman Northrop Grumman Kurt Ketola Raytheon Space and Airborne Systems Rolf Kich Flight Microwave Corporation Rami Kishek...Rolf Kich FMC Rami Kishek University of Maryland Kevin Lim FMC Jared Lucey GSFC Jerry Michaelson The Aerospace Corporation Raul Perez JPL Stu Quade

  8. Prevention of childhood injuries (part 2)

    African Journals Online (AJOL)

    young population are not a top priority of policy makers and health practitioners. Two very important reference points ... The first article[5] identifies energy poverty, prevalent in under- resourced communities, as a key ... petroleum gas and solar power, is a long-term safety and energy priority. The second article[6] assesses ...

  9. 76 FR 72120 - Oil Pollution Prevention; Spill Prevention, Control, and Countermeasure (SPCC) Rule-Compliance...

    Science.gov (United States)

    2011-11-22

    ... Oil Pollution Prevention; Spill Prevention, Control, and Countermeasure (SPCC) Rule--Compliance Date... rule will be effective November 22, 2011. List of Subjects in 40 CFR Part 112 Oil pollution prevention... Regulations is amended as follows: PART 112--OIL POLLUTION PREVENTION 0 1. The authority citation for part 112...

  10. Rape prevention

    Science.gov (United States)

    Date rape - prevention; Sexual assault - prevention ... Centers for Disease Control and Prevention website. Sexual assault and abuse and STDs. In: 2015 sexually transmitted diseases treatment guidelines 2015. www.cdc.gov/std/tg2015/sexual- ...

  11. Dengue Prevention

    Science.gov (United States)

    ... Address What's this? Submit What's this? Submit Button Prevention Recommend on Facebook Tweet Share Compartir This photograph ... medications to treat a dengue infection. This makes prevention the most important step, and prevention means avoiding ...

  12. Plague Prevention

    Science.gov (United States)

    ... Healthcare Professionals Clinicians Public Health Officials Veterinarians Prevention History of Plague Resources FAQ Prevention Recommend on Facebook Tweet Share Compartir Reduce rodent habitat around your ...

  13. Prevention of malignant neoplasms

    OpenAIRE

    D. G. Zaridze; D. M. Maksimovich

    2017-01-01

    Research in causation of cancer is an important part of cancer research in general and is an essential prerequisite for cancer prevention. The effective primary prevention is not visible without evidence based knowledge in the causation of cancer in humans.There is sufficient evidence that certain life style and environment factors cause cancer in humans. These factors include: smoking and other types of tobacco consumption, overweight and obesity, lack of physical activity, diet rich in proc...

  14. Preventing Addiction.

    Science.gov (United States)

    Moore, Susan Fordney

    The purpose of this paper is to provide the beginning counselor with an overview of prevention concepts. Prevention is a relatively new emphasis in community efforts to stem the rising costs of substance abuse and other high-risk behaviors. The paper discusses agent, host, and environmental prevention models and how they relate to causal theories…

  15. Prevention: Exercise

    Medline Plus

    Full Text Available ... Steroid Injections Lumbar Zygapophysical (Facet) Joint Injections PREVENTION Lifestyle Choices 10 Tips for a Healthy Back Smoking Weight Patient Safety Exercise Strengthening Strengthen ...

  16. Prevention: Exercise

    Medline Plus

    Full Text Available ... Injections PREVENTION Lifestyle Choices 10 Tips for a Healthy Back Smoking Weight Patient Safety Exercise Strengthening Strengthen Your Core! Stretching/Flexibility Aerobic Exercise ...

  17. Prevention: Exercise

    Medline Plus

    Full Text Available ... Watchful Waiting and Education Injection Treatments for Spinal Pain Epidural Steroid Injections Lumbar Zygapophysical (Facet) Joint Injections PREVENTION Lifestyle Choices 10 ...

  18. Poison Prevention

    Science.gov (United States)

    ... Prevention Listen Español Text Size Email Print Share Poison Prevention Page Content Article Body Post the Poison Help number 1-800-222-1222 on the ... or empty container of a toxic substance, call Poison Help immediately. More than a million American children ...

  19. Motorcycle Parts

    Science.gov (United States)

    1993-01-01

    An article in NASA Tech Briefs describing a vacuum bagging process for forming composite parts helped a small Oklahoma Company to improve its manufacturing process. President of Performance Extremes, Larry Ortega, and his partners make motorcycle parts from carbon/epoxy to reduce weight. Using vacuum bags, parts have a better surface and fewer voids inside. When heat used in the vacuum bag process caused deformation upon cooling, a solution found in another tech brief solved the problem. A metal plate inside the vacuum bag made for more even heat transfer. A third article described a simple procedure for repairing loose connector pins, which the company has also utilized.

  20. Preventive analgesia

    DEFF Research Database (Denmark)

    Dahl, Jørgen B; Kehlet, Henrik

    2011-01-01

    This paper will discuss the concepts of pre-emptive and preventive analgesia in acute and persistent postsurgical pain, based on the most recent experimental and clinical literature, with a special focus on injury-induced central sensitization and the development from acute to chronic pain. Recent...... of preventive analgesia for persistent postoperative pain are promising. However, clinicians must be aware of the demands for improved design of their clinical studies in order to get more conclusive answers regarding the different avenues for intervention. Summary: The concept of preventive analgesia is still...

  1. Prevention: Exercise

    Medline Plus

    Full Text Available ... Exercise Strength Training for the Elderly Other Back Pack Safety Pregnancy and Back Pain Preventing Osteoporosis Back ... in very slightly. Hold a ball directly in front of you. Keep your abdominal muscles tight and ...

  2. Prevention: Exercise

    Medline Plus

    Full Text Available ... Tips for a Healthy Back Smoking Weight Patient Safety Exercise Strengthening Strengthen Your Core! Stretching/Flexibility Aerobic ... Strength Training for the Elderly Other Back Pack Safety Pregnancy and Back Pain Preventing Osteoporosis Back Pain ...

  3. Prevent Shingles

    Science.gov (United States)

    ... Submit What's this? Submit Button Past Emails Prevent Shingles Language: English (US) Español (Spanish) Recommend on Facebook ... that can result in vision loss. Older Adults & Shingles As you get older, you are more likely ...

  4. Prevention: Exercise

    Medline Plus

    Full Text Available ... Epidural Steroid Injections Lumbar Zygapophysical (Facet) Joint Injections PREVENTION Lifestyle Choices 10 Tips for a Healthy Back Smoking Weight Patient Safety Exercise Strengthening Strengthen Your Core! ...

  5. Prevention: Exercise

    Medline Plus

    Full Text Available ... and Education Injection Treatments for Spinal Pain Epidural Steroid Injections Lumbar Zygapophysical (Facet) Joint Injections PREVENTION Lifestyle ... Z Spine Specialists Videos 9 for Spine Epidural Steroid Injections Exercise: The Backbone of Spine Treatment Spondylolisthesis ...

  6. Prevention: Exercise

    Medline Plus

    Full Text Available ... A SPECIALIST Prevention Strengthening Exercise Committee Exercise Committee Core Strengthening Many popular forms of exercise focus on ... acute pain, you should stop doing it. Transverse Core Strengthening This strengthens the muscles that cross from ...

  7. Prevention: Exercise

    Medline Plus

    Full Text Available ... Lumbar Zygapophysical (Facet) Joint Injections PREVENTION Lifestyle Choices 10 Tips for a Healthy Back Smoking Weight Patient ... the floor; rotate from side to side. Repeat 10 times. Check with your physician; if you are ...

  8. Prevention: Exercise

    Medline Plus

    Full Text Available ... Pregnancy and Back Pain Preventing Osteoporosis Back Pain Basics Book RESOURCES Patient ... popular forms of exercise focus on core strengthening, or building the muscles that provide support for your body. Pilates, yoga and martial arts ...

  9. HIV Prevention

    Centers for Disease Control (CDC) Podcasts

    2012-02-01

    Dr. Kevin Fenton, Director of CDC’s National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, talks about steps people can take to protect their health from HIV.  Created: 2/1/2012 by National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP).   Date Released: 2/1/2012.

  10. Overturn the upside-down world. Stylistic implications of the carnivalesque traced in Giordano Bruno’s The candle-bearer

    Directory of Open Access Journals (Sweden)

    Giacomo Morbiato

    2016-11-01

    After a short review of the main thematic elements, the analysis of the carnivalistic aspects focuses on some dialogical and linguistic elements that are connected to the rhetoric of parody. In addition to the obscene deformation of the biblical-lyturgical statements, some of the most meaningful phenomena are given by the participants taking part in the dialogues, with their ability to lower the tone, and by the usage of the bakhtinian hybrid utterance, which is employed by the author with a dual effect. In general, the analysis, which is here summarily presented with the intention to postpone a systematic study, seems to confirm the importance of the carnivalistic code as not only a linguistic but also an imaginative device of the comedy: his dual value persists and allows not to make absolute generalization about the negativity of the depicted world.

  11. Bullying Prevention

    Science.gov (United States)

    Kemp, Patrice

    2016-01-01

    The focus of the milestone project is to focus on bridging the gap of bullying and classroom instruction methods. There has to be a defined expectations and level of accountability that has to be defined when supporting and implementing a plan linked to bullying prevention. All individuals involved in the student's learning have to be aware of…

  12. Prevention: Exercise

    Medline Plus

    Full Text Available ... Strengthen Your Core! Stretching/Flexibility Aerobic Exercise Cervical Exercise Strength Training for the Elderly Other Back Pack Safety Pregnancy and Back Pain Preventing Osteoporosis Back Pain Basics Book RESOURCES ... The Backbone of Spine Treatment Spondylolisthesis BLOG FIND ...

  13. Prevent Pneumonia

    Centers for Disease Control (CDC) Podcasts

    2015-08-06

    CDC’s Matthew Westercamp explains what pneumonia is, its symptoms, and how to prevent it.  Created: 8/6/2015 by National Center for Immunization and Respiratory Diseases (NCIRD), Division of Bacterial Diseases (DBD), Respiratory Diseases Branch (RDB).   Date Released: 8/6/2015.

  14. HIV Prevention

    Science.gov (United States)

    ... Abroad Treatment Basic Statistics Get Tested Find an HIV testing site near you. Enter ZIP code or city Follow HIV/AIDS CDC HIV CDC HIV/AIDS See RSS | ... Collapse All Is abstinence the only 100% effective HIV prevention option? Yes. Abstinence means not having oral, ...

  15. Prevention: Exercise

    Medline Plus

    Full Text Available ... Information Feature Articles Patient Q&A Success Stories Definitions Anatomy of the Spine Definitions A-Z Spine Specialists Videos 9 for Spine Epidural Steroid Injections Exercise: The Backbone of Spine Treatment Spondylolisthesis BLOG FIND A SPECIALIST Prevention ...

  16. A modeling sensitivity study of the influence of the Atlantic meridional overturning circulation on neodymium isotopic composition at the Last Glacial Maximum

    Directory of Open Access Journals (Sweden)

    T. Arsouze

    2008-09-01

    Full Text Available Using a simple parameterisation that resolves the first order global Nd isotopic composition (hereafter expressed as εNd in an Ocean Global Circulation Model, we have tested the impact of different circulation scenarios on the εNd in the Atlantic for the Last Glacial Maximum (LGM, relative to a modern control run. Three different LGM freshwater forcing experiments are performed to test for variability in the εNd oceanic distribution as a function of ocean circulation. Highly distinct representations of the ocean circulation are generated in the three simulations, which drive significant differences in εNd, particularly in deep waters of the western part of the basin. However, at the LGM, the Atlantic is more radiogenic than in the modern control run, particularly in the Labrador basin and in the Southern Ocean. A fourth experiment shows that changes in Nd sources and bathymetry drive a shift in the εNd signature of the basin that is sufficient to explain the changes in the εNd signature of the northern end-member (NADW or GNAIW glacial equivalent in our LGM simulations. All three of our LGM circulation scenarios show good agreement with the existing intermediate depth εNd paleo-data. This study cannot indicate the likelihood of a given LGM oceanic circulation scenario, even if simulations with a prominent water mass of southern origin provide the most conclusive results. Instead, our modeling results highlight the need for more data from deep and bottom waters from western Atlantic, where the εNd change in the three LGM scenarios is the most important (up to 3 εNd. This would also aid more precise conclusions concerning the evolution of the northern end-member εNd signature, and thus the potential use of εNd as a tracer of past oceanic circulation.

  17. Body parts

    Science.gov (United States)

    Ayiter, Elif

    2010-01-01

    In this project, the artist wishes to examine corporeality in the virtual realm, through the usage of the (non)-physical body of the avatar. An art installation created in the virtual world of Second Life, which is meant to be accessed with site specific avatars, will provide the creative platform whereby this investigation is undertaken. Thus, "body parts" seeks to challenge the residents of virtual environments into connecting with the virtual manifestations, i.e., avatars of others in an emotionally expressive/intimate manner.

  18. Proceedings from the National Cancer Institute's Second International Workshop on the Biology, Prevention, and Treatment of Relapse after Hematopoietic Stem Cell Transplantation: Part I. Biology of relapse after transplantation.

    Science.gov (United States)

    Gress, Ronald E; Miller, Jeffrey S; Battiwalla, Minoo; Bishop, Michael R; Giralt, Sergio A; Hardy, Nancy M; Kröger, Nicolaus; Wayne, Alan S; Landau, Dan A; Wu, Catherine J

    2013-11-01

    In the National Cancer Institute's Second Workshop on the Biology, Prevention, and Treatment of Relapse after Hematopoietic Stem Cell Transplantation, the Scientific/Educational Session on the Biology of Relapse discussed recent advances in understanding some of the host-, disease-, and transplantation-related contributions to relapse, emphasizing concepts with potential therapeutic implications. Relapse after hematopoietic stem cell transplantation (HSCT) represents tumor escape, from the cytotoxic effects of the conditioning regimen and from immunologic control mediated by reconstituted lymphocyte populations. Factors influencing the biology of the therapeutic graft-versus-malignancy (GVM) effect-and relapse-include conditioning regimen effects on lymphocyte populations and homeostasis, immunologic niches, and the tumor microenvironment; reconstitution of lymphocyte populations and establishment of functional immune competence; and genetic heterogeneity within the malignancy defining potential for clonal escape. Recent developments in T cell and natural killer cell homeostasis and reconstitution are reviewed, with implications for prevention and treatment of relapse, as is the application of modern genome sequencing to defining the biologic basis of GVM, clonal escape, and relapse after HSCT. Published by Elsevier Inc.

  19. DETERM INI NG THE FACTORS WH I CH CAN PREVENT RECREAT I ONAL PART ICIPAION OF UNI VERS I TY STUDENTS WHO A TTEND TO THE DEPARTMENTS ACCORDI NG TO SPEC I AL SK I LL EXAMS

    Directory of Open Access Journals (Sweden)

    Ersan TOLUKAN

    2016-07-01

    Full Text Available The a im of this study was to de termine the factors that prevent the students who studies in the Physical Education and Sport, Musical Education and Painting Departments which request aptitude test, from participating into the recreational activities. Population of the research is consti tuted by total 1918 students who were studying at Gazi University in 2009 - 2010 Academic Years in Physical Education and Sport (1205, Musical Education (216 and Art Education Departments (497 which request aptitude test. Totally 498 volunteer participant s constitute the research‟s sample; 221 students from Physical Education and Sport, 116 students from Musical Education and 161 students from Art Education Departments. Working as a data collection tool and a total of 27 items of the six sub - dime nsions "Le isure Barriers Scale " is used.6 subscales of the questionnaire used in the study to test gender differences in the independent samples t - test analysis was conducted based on the results; by gender "individual psychology in" the (p<0.05 were found to be si gnificant differences . In addition, the ANOVA results, according to the welfare level (individual psychology and lack of interest and section variables and leisure difficulty according to their (individual psychology, lack of friends and lack of interest were statistically significant d ifferences that were observed ( p<0.05 . Consequent ly, the "lack of interest", " facilities/ lack of service " and "individual psychology" factor in preventing the individuals to participate in recreational activities has be en determined that the first three ranks.

  20. Toward a high-performance management system in health care, part 4: Using high-performance work practices to prevent central line-associated blood stream infections-a comparative case study.

    Science.gov (United States)

    McAlearney, Ann Scheck; Hefner, Jennifer; Robbins, Julie; Garman, Andrew N

    2016-01-01

    Central line-associated bloodstream infections (CLABSIs) are among the most harmful health care-associated infections and a major patient safety concern. Nationally, CLABSI rates have been reduced through the implementation of evidence-based interventions; thus far, however, hospitals still differ substantially in their success implementing these practices. Prior research on high-performance work practices (HPWPs) suggests that these practices may explain some of the differences health systems experience in the success of their quality improvement efforts; however, these relationships have not yet been systematically investigated. In this study, we sought to explore the potential role HPWPs may play in explaining differences in the success of CLABSI reduction efforts involving otherwise similar organizations and approaches. To form our sample, we identified eight hospitals participating in the federally funded "On the CUSP: Stop BSI" initiative. This sample included four hospital "pairs" matched on organizational characteristics (e.g., state, size, teaching status) but having reported contrasting CLABSI reduction outcomes. We collected data through site visits as well as 194 key informant interviews, which were framed using an evidence-informed model of health care HPWPs. We found evidence that, at higher performing sites, HPWPs facilitated the adoption and consistent application of practices known to prevent CLABSIs; these HPWPs were virtually absent at lower performing sites. We present examples of management practices and illustrative quotes categorized into four HPWP subsystems: (a) staff engagement, (b) staff acquisition/development, (c) frontline empowerment, and (d) leadership alignment/development. We present the HPWP model as an organizing framework that can be applied to facilitate quality and patient safety efforts in health care. Managers and senior leaders can use these four HPWP subsystems to select, prioritize, and communicate about management

  1. Znaczenie Dobrego Krzesła, jako elementu szkolnego i domowego środowiska ucznia, w profilaktyce zaburzeń statyki postawy ciała = The significance of Good Chair as part of children’s school and home environment in the preventive treatment of body statistics distortions

    OpenAIRE

    Mrozkowiak, Mirosław; Żukowska, Hanna

    2015-01-01

    Mrozkowiak Mirosław, Żukowska Hanna. Znaczenie Dobrego Krzesła, jako elementu szkolnego i domowego środowiska ucznia, w profilaktyce zaburzeń statyki postawy ciała = The significance of Good Chair as part of children’s school and home environment in the preventive treatment of body statistics distortions. Journal of Education, Health and Sport. 2015;5(7):179-215. ISSN 2391-8306. DOI 10.5281/zenodo.19832 http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%287%29%3A179-215 https:...

  2. Allergy prevention.

    Science.gov (United States)

    Muche-Borowski, Cathleen; Kopp, Matthias; Reese, Imke; Sitter, Helmut; Werfel, Thomas; Schäfer, Torsten

    2010-09-01

    The further increase of allergies in industrialized countries demands evidence-based measures of primary prevention. The recommendations as published in the guideline of 2004 were updated and consented on the basis of a systematic literature search. Evidence from the period February 2003-May 2008 was searched in the electronic databases Cochrane and MEDLINE as well as in reference lists of recent reviews and by contacting experts. The retrieved citations were screened for relevance first by title and abstract and in a second step as full paper. Levels of evidence were assigned to each included study and the methodological quality of the studies was assessed as high or low. Finally the revised recommendations were formally consented (nominal group process) by representatives of relevant societies and organizations including a self-help group. Of originally 4556 hits, 217 studies (4 Cochrane Reviews, 14 meta-analyses, 19 randomized controlled trials, 135 cohort and 45 case-control studies) were included and critically appraised. Grossly unchanged remained the recommendations on avoiding environmental tobacco smoke, breast-feeding over 4 months (alternatively hypoallergenic formulas for children at risk), avoiding a mold-promoting indoor climate, vaccination according to current recommendations, and avoidance of furry pets (especially cats) in children at risk. The recommendation on reducing the house dust mite allergen exposure as a measure of primary prevention was omitted and the impact of a delayed introduction of supplementary food was reduced. New recommendations were adopted concerning fish consumption (during pregnancy / breast-feeding and as supplementary food in the first year), avoidance of overweight, and reducing the exposure to indoor and outdoor air pollutants. The revision of this guideline on a profound evidence basis led to (1) a confirmation of existing recommendations, (2) substantial revisions, and (3) new recommendations. Thereby it is possible

  3. (segunda parte

    Directory of Open Access Journals (Sweden)

    José María Oliva-Martínez

    2004-01-01

    Full Text Available Este trabajo es la continuación de otro anterior (Oliva, 2004, ambos dedicados al estudio de la importancia del pensamiento analógico en la construcción histórica de la noción de fuerza gravitatoria y del modelo de Sistema Solar. En aquella ocasión analizamos dicho papel durante el período comprendido desde las antiguas civilizaciones hasta llegar a la revolución copernicana con científicos como Copérnico, Gilbert, Kepler o el propio Galileo. En esta segunda parte, se continúa con algunos de los razonamientos analógicos proporcionados desde la vertiente mecanicista, capitaneada por Descartes y desde la tradición subsiguiente que se desarrolló en línea con la utilización del método de la analogía como criterio argumentativo (Huyghens, Hooke, Bernoulli, etc.. Dedicamos asimismo un capítulo aparte a la figura de Newton, quien continúa con dicha tradición en su intento de explicar la naturaleza de la gravitación. Finalmente se procede, a modo de síntesis, a realizar una clasificación de distintos tipos de razonamientos analógicos aportados en el desarrollo histórico en torno a estos temas, estudiando el papel científico y divulgativo de cada uno

  4. Second meeting of the French CEIP (Centres d'Evaluation et d'Information sur la Pharmacodépendance). Part I: how to evaluate and prevent the abuse and dependence on hypnotic/anxiolytic drugs?

    Science.gov (United States)

    Micallef-Roll, Joëlle; Lapeyre-Mestre, Maryse

    2009-01-01

    The second meeting of the French CEIP (Centres d'Evaluation et d'Information sur la Pharmacodépendance) was organized during the annual congress of the French Society of Pharmacology Therapeutics and Physiology in 2008. The aim of this meeting was to update the knowledge on abuse and dependence of the anxiolytics and hypnotics from different points of view (pharmacoepidemiology, epidemiology and treatment). The first part of this meeting summarized the pharmacological data obtained by the pharmacoepidemiological tools developed by the CEIP network. Even if the abuse liability of these agents is not a new problem, it remains always present and characterized by differences of misuse between drugs in real-life settings. The second part targeted to a subtype of consumers, the elderly population, because older patients are more likely to be prescribed with multiple prescriptions and also more at risk for prescription abuse. Despite this evidence, there is a scarcity of information on the factors associated with a such behaviour and its screening, assessment, diagnosis and treatment.

  5. Unavowed Abstention Can Overturn Poll Predictions

    Directory of Open Access Journals (Sweden)

    Serge Galam

    2018-03-01

    Full Text Available I revisit the 2017 French Presidential election which opposed the far right National Front candidate Marine Le Pen against the center candidate Emmanuel Macron. While voting intentions for Le Pen stuck below 50% and polls kept predicting her failure, I warned on the emergence of a novel phenomenon I defined as unavowed abstention, which could suddenly reverse the ranking at Le Pen benefit on the voting day. My warning got a massive media coverage. She eventually lost the runoff at a score worse than predicted by the polls. Using a quantitative mathematical framing, which reveals the existence of tipping points in respective turnouts, I show that the predicted phenomenon of unavowed abstention did happen. But instead of shattering the expected outcome, against all odds it occurred at Le Pen expense, therefore without impact on the final outcome. The results shed a new light on other national cases such as Obama and Trump victories in the US.

  6. Innovative Alternatives to Lifting Overturned Military Vehicles

    Science.gov (United States)

    2014-04-25

    and sensitive equipment underneath. The current means of lifting the large weights is to use large and bulky pneumatic lifting bags. In an...buckling was investigated assuming the cylinder is simulated to be cantilevered on one side and free on the other, and that the full weight is acting in...be as lightweight and compact as possible. One idea for the implementation of these designs is to include them with any large military vehicle; this

  7. Unavowed Abstention Can Overturn Poll Predictions

    Science.gov (United States)

    Galam, Serge

    2018-03-01

    I revisit the 2017 French Presidential election which opposed the far right National Front candidate Marine Le Pen against the center candidate Emmanuel Macron. While voting intentions for Le Pen stuck below 50% and polls kept predicting her failure, I warned on the emergence of a novel phenomenon I defined as unavowed abstention, which could suddenly reverse the ranking at Le Pen benefit on the voting day. My warning got a massive media coverage. She eventually lost the runoff at a score worse than predicted by the polls. Using a quantitative mathematical framing, which reveals the existence of tipping points in respective turnouts, I show that the predicted phenomenon of unavowed abstention did happen. But instead of shattering the expected outcome, against all odds it occurred at Le Pen expense, therefore without impact on the final outcome. The results shed a new light on other national cases such as Obama and Trump victories in the US.

  8. Teleophthalmology in preventive medicine

    CERN Document Server

    Michelson, Georg

    2014-01-01

    This book provides an up-to-date overview of the clinical applications, methods, and technologies of teleophthalmology within the field of preventive medicine. The ability of novel methods to detect the initial signs of neurodegenerative diseases on the basis of alterations in the retina is reviewed, and detailed attention is paid to the role of teleophthalmology in screening for vision-threatening diseases such as diabetic retinopathy, glaucoma, and age-related macular degeneration. A major part of the book is devoted to novel imaging methods and the latest information technologies, including advanced mobile communication and Web 2.0 applications in teleophthalmology. In addition, the initial projects of an interdisciplinary cooperation in preventive medicine are described. All of the authors are experienced in the scientific and practical aspects of teleophthalmology, including e-learning, and have produced a book that will meet the needs of all medical care providers interested in using teleophthalmology.

  9. Rotating preventers

    International Nuclear Information System (INIS)

    Tangedahl, M.J.; Stone, C.R.

    1992-01-01

    This paper reports that recent changes in the oil and gas industry and ongoing developments in horizontal and underbalanced drilling necessitated development of a better rotating head. A new device called the rotating blowout preventer (RBOP) was developed by Seal-Tech. It is designed to replace the conventional rotating control head on top of BOP stacks and allows drilling operations to continue even on live (underbalanced) wells. Its low wear characteristics and high working pressure (1,500 psi) allow drilling rig crews to drill safely in slightly underbalanced conditions or handle severe well control problems during the time required to actuate other BOPs in the stack. Drilling with a RBOP allows wellbores to be completely closed in tat the drill floor rather than open as with conventional BOPs

  10. Preventing and diagnosing dementia.

    Science.gov (United States)

    Keenan, Bernie; Jenkins, Catharine; Ginesi, Laura

    While dementia is an umbrella term for a range of degenerative brain disorders, many share similar presentations. Nurses are ideally placed to identify those at risk and empower them to access treatment and plan and prepare for their future needs--as such, they need up-to-date knowledge of the signs and symptoms of the different types of dementia to identify risk factors and make an informed diagnosis. This article, the third in a four-part series on dementia, examines the risk factors, signs, symptoms and diagnosis of dementia, as well as outlining lifestyle factors such as diet and exercise that may help to prevent the development of the condition.

  11. Treating and Preventing Burns

    Science.gov (United States)

    ... Healthy Living Healthy Living Healthy Living Nutrition Fitness Sports Oral Health Emotional Wellness Growing Healthy Sleep Safety & Prevention Safety & Prevention Safety and Prevention Immunizations At Home ...

  12. Relapse prevention.

    Science.gov (United States)

    Hall, S M; Wasserman, D A; Havassy, B E

    1991-01-01

    Although knowledge about relapse prevention is still at an early stage, the extant data highlight the importance of several constructs. 1. Motivation for abstinence remains central. The construct itself is often clouded because of its association with mystical notions such as willpower and self-control. We know that manipulation of environmental events can increase motivation. These interventions are effective, however, only as long as the contingencies are in effect. We need to develop and evaluate strategies for transferring contingency management to the natural environment, that is, to institutions and groups that can perpetuate them for the long term. Also, clarification of the kinds of abstinence goals needed to prevent relapse is important. 2. Coping skills have been studied by several investigators, but research on these, except for job-finding skills, is not encouraging. The skills usually taught may be too basic. Skills training oriented to complex targets, such as building nondrug-using networks, may be useful and should be further explored. 3. Social support is clearly important, yet we do not know how best to use it to promote abstinence. The little research available suggests that both familial and nonfamilial systems should be mobilized. We need to define abstinence-promoting supportive behaviors, identify and engage important support systems in treatment, and help patients expand their nondrug-using contacts. 4. Negative affect may be causally related to relapse. We need to continue efforts to identify dysphoric patients and develop interventions to ameliorate dysphoria concurrent with drug abuse treatment (cf. Zweben and Smith 1989). 5. Drug cue reactivity and extinction to drug cues have been demonstrated in the laboratory. What is needed in this promising line of research are (1) investigation of cues and cue-reactivity phenomena in the natural environment or in conditions closely mimicking that environment and (2) extinction methods that transfer

  13. Polio and Prevention

    Science.gov (United States)

    ... Photo Collections Videos Polio Today → Polio + Prevention Polio + Prevention Polio and prevention Polio is a crippling and ... a child for life. Learn more about polio + prevention The Virus The Vaccines The Communities Related resources ...

  14. Diabetes Prevention Program (DPP)

    Science.gov (United States)

    ... Recruiting Patients & Families Consortia, Networks & Centers Reports & Planning Diabetes Prevention Program (DPP) The NIDDK-sponsored Diabetes Prevention ... Diabetes Prevention Program for those who are eligible. Diabetes Prevention Program (DPP) DPP Goal The DPP looked ...

  15. Prevention of malignant neoplasms

    Directory of Open Access Journals (Sweden)

    D. G. Zaridze

    2017-01-01

    Full Text Available Research in causation of cancer is an important part of cancer research in general and is an essential prerequisite for cancer prevention. The effective primary prevention is not visible without evidence based knowledge in the causation of cancer in humans.There is sufficient evidence that certain life style and environment factors cause cancer in humans. These factors include: smoking and other types of tobacco consumption, overweight and obesity, lack of physical activity, diet rich in processed meat and poor in vegetables and fruits, certain types of viral and bacterial infection, ultraviolet radiation, ionizing radiation, ambient air pollution, carcinogens at workplace, exogenous hormones.Cancer mortality is decreasing in majority of developed countries, including Russia. This mortality trend is mostly due to decrease in incidence and death rates of lung and other smoking related cancers and is caused by decline in smoking prevalence and change in tar content of cigarette smoke.In Russia trend in mortality from all cancers is as well determined by decrease in incidence and mortality from gastric cancer, which is due to decline in prevalence of Helicobacter pylori infection and improvement of diet, increase in consumption of fruits and vegetables. Thus the decline in cancer mortality is mostly the result of primary prevention which is the most effective avenue of cancer control. 

  16. Osteoradionecrosis prevention myths

    International Nuclear Information System (INIS)

    Wahl, Michael J.

    2006-01-01

    Purpose: To critically analyze controversial osteoradionecrosis (ORN) prevention techniques, including preradiation extractions of healthy or restorable teeth and the use of prophylactic antibiotics or hyperbaric oxygen (HBO) treatments for preradiation and postradiation extractions. Methods: The author reviewed ORN studies found on PubMed and in other article references, including studies on overall ORN incidence and pre- and postradiation incidence, with and without prophylactic HBO or antibiotics. Results: Owing in part to more efficient radiation techniques, the incidence of ORN has been declining in radiation patients over the last 2 decades, but the prevention of ORN remains controversial. A review of the available literature does not support the preradiation extraction of restorable or healthy teeth. There is also insufficient evidence to support the use of prophylactic HBO treatments or prophylactic antibiotics before extractions or other oral surgical procedures in radiation patients. Conclusions: To prevent ORN, irradiated dental patients should maintain a high level of oral health. A preradiation referral for a dental evaluation and close collaboration by a multidisciplinary team can be invaluable for radiation patients. As with most other dental patients, restorable and healthy teeth should be retained in irradiated patients. The use of prophylactic HBO or antibiotics should be reconsidered for preradiation and postradiation extractions

  17. Rickets: Part I.

    Science.gov (United States)

    Shore, Richard M; Chesney, Russell W

    2013-01-01

    Rickets is characterized by impaired mineralization and ossification of the growth plates of growing children caused by a variety of disorders, the most frequent of which is nutritional deficiency of vitamin D. Despite ample knowledge of its etiology and the availability of cost-effective methods of preventing it, vitamin D deficiency rickets remains a significant problem in developing and developed countries. This two-part review covers the history, etiology, pathophysiology and clinical and radiographical findings of vitamin D deficiency rickets. Other less frequent causes of rickets and some of the disorders entering into the differential diagnoses of rickets are also considered. Controversial issues surrounding vitamin D deficiency include determination of what constitutes vitamin D sufficiency and the potential relationship between low levels of vitamin D metabolites in many individuals and unexplained fractures in infants.

  18. 76 FR 16521 - National Poison Prevention Week, 2011

    Science.gov (United States)

    2011-03-23

    ... March 23, 2011 Part III The President Proclamation 8638--National Poison Prevention Week, 2011 #0; #0..., 2011 National Poison Prevention Week, 2011 By the President of the United States of America A... cases, these tragic incidents are preventable. During National Poison Prevention Week, I encourage all...

  19. Report on a survey in fiscal 1999. The survey on structuring institutions for energy environment policies. Part 2. Collection of information about policies in major countries for prevention of global warming; 1999 nendo energy kankyo seisaku no seido kochiku ni kansuru chosa. 2. Kakkoku ondanka boshi seisaku johoshu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The present survey is intended to collect and put in order the literatures and items of information related to: the current status and future directionality in the policies in advanced nations related to achieving the targets of the Kyoto Protocol, and trends of improving national institutions to respond to the Kyoto mechanisms, and the background of the conceptions thereof (including the conceptions on designing the international institutions). The survey gives considerations at the same time on possibilities of realization of the policies being implement and/or discussed. The report consists of two parts. Part 1 puts in order the trends until the most recent date in the summary of warming prevention policies in the major European and North American countries, placing the importance on the policies and measures that use economic methods (environment taxation system, national discharge quantity transaction, voluntary action plans and agreements). Part 2 (the present paper) introduces the contents of the major literatures and administrative materials in the policy trends in each nation, and puts in order the basic items of information that are considered useful for performing in the future the surveys related to the subject areas. (NEDO)

  20. Models for effective prevention.

    Science.gov (United States)

    Perry, C L; Kelder, S H

    1992-07-01

    The social influence models do provide some optimism for primary prevention efforts. Prevention programs appear most effective when 1) the target behavior of the intervention has received increasing societal disapproval (such as cigarette smoking), 2) multiple years of behavioral health education are planned, and 3) community-wide involvement or mass media complement a school-based peer-led program (45,46). Short-term programs and those involving alcohol use have had less favorable outcomes. Future research in primary prevention should address concerns of high-risk groups and high-risk countries, such as lower income populations in the United States or countries that have large adolescent homeless populations. The utilization of adolescent leaders for program dissemination might be particularly critical in these settings. A second major and global concern should focus upon alcohol use and alcohol-related problems. In many communities adolescent alcohol use is normative and even adult supported. Thus, young people are getting quite inconsistent messages on alcohol from their schools, from TV, from peers, and from parents. This inconsistency may translate into many tragic and avoidable deaths for young people. Clearly, in the area of alcohol-related problems, community-wide involvement may be necessary. A third direction for prevention research should involve issues of norms, access, and enforcement including policy interventions, such as involve the availability of cigarette vending machines or the ease of under-age buying or levels of taxation. These methods affect adolescents more acutely since their financial resources, for the most part, are more limited. These policy level methods also signify to adolescents what adults consider appropriate.(ABSTRACT TRUNCATED AT 250 WORDS)

  1. Impetigo: Tips for Treatment and Prevention

    Science.gov (United States)

    ... DO Videos Contact Close ‹ Back to Healthy Living Impetigo: Tips for Treatment and Prevention The symptoms of ... to other parts of their bodies. Causes of Impetigo Impetigo usually affects preschool and school-aged children, ...

  2. Pressure ulcers : predicting factors, prevention and costs

    OpenAIRE

    Demarré, Liesbet

    2014-01-01

    The research outline pursued with this thesis can be divided in three parts. In the first part, studies to compare the effectiveness of several interventions for the prevention of pressure ulcers were conducted. Pressure ulcer prevention focusses on the reduction of the amount and duration of pressure and shear. An alternating device intermittently removes pressure and shear from vulnerable areas. It provides pressure relief via cyclic inflating and deflating air cells. Systematic reviews an...

  3. Tropical diabetic hand syndrome: prevention through education ...

    African Journals Online (AJOL)

    Tropical diabetic hand syndrome describes an acute symptom complex found in patients with diabetes in the tropics, usually following minor trauma to the hand. Two different ... Education remains the most important preventive tool in underdeveloped countries, and should remain an integral part of prevention. Keywords: ...

  4. Prevention of diseases after menopause.

    Science.gov (United States)

    Lobo, R A; Davis, S R; De Villiers, T J; Gompel, A; Henderson, V W; Hodis, H N; Lumsden, M A; Mack, W J; Shapiro, S; Baber, R J

    2014-10-01

    Women may expect to spend more than a third of their lives after menopause. Beginning in the sixth decade, many chronic diseases will begin to emerge, which will affect both the quality and quantity of a woman's life. Thus, the onset of menopause heralds an opportunity for prevention strategies to improve the quality of life and enhance longevity. Obesity, metabolic syndrome and diabetes, cardiovascular disease, osteoporosis and osteoarthritis, cognitive decline, dementia and depression, and cancer are the major diseases of concern. Prevention strategies at menopause have to begin with screening and careful assessment for risk factors, which should also include molecular and genetic diagnostics, as these become available. Identification of certain risks will then allow directed therapy. Evidence-based prevention for the diseases noted above include lifestyle management, cessation of smoking, curtailing excessive alcohol consumption, a healthy diet and moderate exercise, as well as mentally stimulating activities. Although the most recent publications from the follow-up studies of the Women's Health Initiative do not recommend menopause hormonal therapy as a prevention strategy, these conclusions may not be fully valid for midlife women, on the basis of the existing data. For healthy women aged 50-59 years, estrogen therapy decreases coronary heart disease and all-cause mortality; this interpretation is entirely consistent with results from other randomized, controlled trials and observational studies. Thus. as part of a comprehensive strategy to prevent chronic disease after menopause, menopausal hormone therapy, particularly estrogen therapy may be considered as part of the armamentarium.

  5. Machining Thin-Walled Cylindrical Parts

    Science.gov (United States)

    Cimbak, Joe; Spagnolo, Jim; Kraus, Dan

    1988-01-01

    Cylindrical walls only few thousandths of inch thick machined accurately and without tears or punctures with aid of beryllium copper mandrel. Chilled so it contracts, then inserted in cylinder. As comes to room temperature, mandrel expands and fits snugly inside cylinder. Will not allow part to slide and provides solid backup to prevent deflection when part machined by grinding wheel. When machining finished, cylinder-and-mandrel assembly inserted in dry ice, mandrel contracts and removed from part.

  6. Preventing congenital toxoplasmosis.

    Science.gov (United States)

    Lopez, A; Dietz, V J; Wilson, M; Navin, T R; Jones, J L

    2000-03-31

    Toxoplasmosis is caused by infection with the protozoan parasite Toxoplasma gondii. Acute infections in pregnant women can be transmitted to the fetus and cause severe illness (e.g., mental retardation, blindness, and epilepsy). An estimated 400-4,000 cases of congenital toxoplasmosis occur each year in the United States. Of the 750 deaths attributed to toxoplasmosis each year, 375 (50%) are believed to be caused by eating contaminated meat, making toxoplasmosis the third leading cause of foodborne deaths in this country. Toxoplasma can be transmitted to humans by three principal routes: a) ingestion of raw or inadequately cooked infected meat; b) ingestion of oocysts, an environmentally resistant form of the organism that cats pass in their feces, with exposure of humans occurring through exposure to cat litter or soil (e.g., from gardening or unwashed fruits or vegetables); and c) a newly infected pregnant woman passing the infection to her unborn fetus. RECOMMENDATIONSFOR PREVENTION: Toxoplasma infection can be prevented in large part by a) cooking meat to a safe temperature (i.e., one sufficient to kill Toxoplasma); b) peeling or thoroughly washing fruits and vegetables before eating; c) cleaning cooking surfaces and utensils afterthey have contacted raw meat, poultry, seafood, or unwashed fruits or vegetables; d) pregnant women avoiding changing cat litter or, if no one else is available to change the cat litter, using gloves, then washing hands thoroughly; and e) not feeding raw or undercooked meat to cats and keeping cats inside to prevent acquisition of Toxoplasma by eating infected prey. Priorities for research were discussed at a national workshop sponsored by CDC in September 1998 and include a) improving estimates of the burden of toxoplasmosis, b) improving diagnostic tests to determine when a person becomes infected with Toxoplasma, and c) determining the applicability of national screening programs. Many cases of congenital toxoplasmosis can be

  7. Condom use as part of the wider HIV prevention strategy ...

    African Journals Online (AJOL)

    Correct and consistent condom usage remains a pivotal strategy in reaching the target set by the South African government to reduce new HIV infections by 50% in the next 5 years. Studies have found that there has been an increase in condom usage by some categories of the population, but usage has not yet reached the ...

  8. Pollution prevention and waste minimization tools workshops: Proceedings. Part 2

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-31

    The purpose of the second workshop was to bring together representatives of DOE and DOE contractor organizations to discuss four topics: process waste assessments (PWAs), a continuation of one of the sessions held at the first workshop in Clearwater; waste minimization reporting requirements; procurement systems for waste minimization; and heating, ventilating, and air conditioning (HVAC) and replacements for chlorofluorocarbons (CFCs). The topics were discussed in four concurrent group sessions. Participants in each group were encouraged to work toward achieving two main objectives: establish a ``clear vision`` of the overall target for their session`s program, focusing not just on where the program is now but on where it should go in the long term; and determine steps to be followed to carry out the target program.

  9. Public attitudes towards prevention of depression.

    Science.gov (United States)

    Schomerus, Georg; Angermeyer, Matthias C; Matschinger, Herbert; Riedel-Heller, Steffi G

    2008-03-01

    Various programs for depression prevention have been shown to be effective, but preventive efforts population wide are only beginning. We examine public attitudes towards prevention of depression and beliefs about helpful preventive measures. Fully structured telephone interview with a representative population sample including people of German nationality older than 14 years (n=1016). 75.4% of the sample agreed on the possibility to prevent depression. Of those, 403 (52.6%) stated that they would take part in prevention programs, and in this group 234 (58.1%) indicated readiness to pay out of their pocket for such programs. Out of a catalogue of 37 proposed actions, psychosocial and lifestyle related measures were preferred. Exploratory factor analysis revealed three factors--proactive lifestyle, relying on medicine, and relaxing--inherent in public beliefs about helpfulness of preventive measures. Higher education reduced willingness, high perceived personal risk of depression and previous contact to the disease increased willingness to take part in preventive programs. The public entertains favourable attitudes and beliefs about prevention of depression that do not conflict with evidence-based programs. Our study thus encourages implementation of population based prevention programs.

  10. Initiatives for proliferation prevention

    International Nuclear Information System (INIS)

    1997-04-01

    Preventing the proliferation of weapons of mass destruction is a central part of US national security policy. A principal instrument of the Department of Energy's (DOE's) program for securing weapons of mass destruction technology and expertise and removing incentives for scientists, engineers and technicians in the newly independent states (NIS) of the former Soviet Union to go to rogue countries or assist terrorist groups is the Initiatives for Proliferation Prevention (IPP). IPP was initiated pursuant to the 1994 Foreign Operations Appropriations Act. IPP is a nonproliferation program with a commercialization strategy. IPP seeks to enhance US national security and to achieve nonproliferation objectives by engaging scientists, engineers and technicians from former NIS weapons institutes; redirecting their activities in cooperatively-developed, commercially viable non-weapons related projects. These projects lead to commercial and economic benefits for both the NIS and the US IPP projects are funded in Russian, Ukraine, Kazakhstan and Belarus. This booklet offers an overview of the IPP program as well as a sampling of some of the projects which are currently underway

  11. Stomach (Gastric) Cancer Prevention

    Science.gov (United States)

    ... likely as white men to die from stomach cancer. Stomach Cancer Prevention Key Points Avoiding risk factors and increasing ... factors and increasing protective factors may help prevent stomach cancer. Avoiding cancer risk factors may help prevent certain ...

  12. Homelessness as social and individual problem – possibilities and prevention

    OpenAIRE

    Małgorzata Piechowicz

    2012-01-01

    This article consists of several parts. The first part includes definitional considerations over the notion of homelessness. It also describes social situation of the homeless, whereas the second part concentrates on both the analysis of causes and effects of homelessness and on the attempt to show the scale of this phenomenon. The last part of the article focuses on the prevention of homelessness. It emphasizes the importance of interdisciplinarity of preventive and compensatory actions in t...

  13. 76 FR 12220 - Petition for Exemption From the Federal Motor Vehicle Motor Theft Prevention Standard; Jaguar...

    Science.gov (United States)

    2011-03-04

    ... Range Rover Evoque vehicle line in accordance with 49 CFR part 543, Exemption from the Theft Prevention... vehicle theft as compliance with the parts-marking requirements of the Theft Prevention Standard (49 CFR... theft prevention standard (49 CFR Part 541) for the Range Rover Evoque vehicle line beginning with MY...

  14. "AN OUNCE OF PREVENTION..."

    Science.gov (United States)

    HASELKORN, FLORENCE

    PREVENTION AS FUNCTION, VALUE ISSUE, CONCEPTUAL SHORTCOMING, AND PRACTICE IS DISCUSSED AND RELATED TO EDUCATIONAL TASK. PREVENTION AS FUNCTION IS GENERATED BY OUR VALUE PREMISES. IN SEEKING TO PREVENT SOME FORMS OF SOCIAL DYSFUNCTION, WE MAY BE PERPETUATING OTHERS. THE CONCEPT OF PREVENTION IS AMBIGUOUS. CRUCIAL CONCEPTUAL ISSUES INCLUDE THE…

  15. Parts, Axial Parts, and Next Parts in Kannada

    Directory of Open Access Journals (Sweden)

    R. Amritavalli

    2007-12-01

    Full Text Available Nouns meaning ‘place, region’ and ‘part’ are compounded in Kannada with a `bleached’ noun (a putative postposition to form AxPart and Part readings. As in other languages, the AxPart or ‘region’ reading does not pluralize, does not permit adjectival modification, and allows for MeasureP modification (unlike the part reading. AxParts may also be formed out of nouns by the fusion of a dative marker or a genitive marker with the N; these case markers introduce the Place element. The dative case may be optionally overt (e.g. pakka-kke ‘side-dative,’ ‘to a side’, or covert (in AxParts like munde ‘front’. The genitive marker gives a sense of immediate adjacency that we designate the NextPart reading. Interestingly, the dative and genitive cases in Kannada also allow nouns to assume the function of predicative and attributive adjectives.

  16. [Prevention of dementia].

    Science.gov (United States)

    Urakami, Katsuya

    2016-03-01

    The dementia prevention consists of three steps, primary prevention of dementia is to prevent from normal and mild cognitive impairment to dementia, secondary prevention is early detection and early treatment of dementia, and tertiary prevention is three stages of progress prevention of dementia. Primary prevention of dementia had been considered impossible until recently, but potential scientific evidence has been shown recently. The fact that 4.62 million people are person with dementia and 400 million people are person with mild cognitive impairment are considered to be urgent problem and we must intend to perform dementia prevention from primary to tertiary prevention thoroughly. We perform dementia screening using touch panel type computer and we recommend person with mild cognitive impairment to join dementia prevention classroom. Therefore, we can prevent progression from mild cognitive impairment to dementia (primary prevention). Early diagnosis and introduction to the specialized medical institution are needed if you find early stage of dementia and treat early (secondary prevention). To prevent progression by the appropriate drug treatment and care for dementia is required (tertiary prevention).

  17. HARM REDUCTION IN THE PREVENTION OF DRUG ADDICTIONS

    OpenAIRE

    KALOUSOVÁ, Dita

    2010-01-01

    This dissertation on Harm Reduction approach in the prevention of drug addictions deals with tertiary drug prevention. It aims to show the importance of how much information about this topic students at comprehensive schools get and have. The theoretical part provides some information about the consequences of drug addiction in general, about drug prevention, substitution treatment, Harm Reduction approach and the services involved. The practical part presents the results of a survey which ai...

  18. CHILD WELFARE IN CANADA : PART II

    OpenAIRE

    松本, 眞一; Shinichi, Matsumoto; 桃山学院大学社会学部

    2006-01-01

    This part study aims to research on the whole aspect of child protection in Canada. And so, this paper consists of five chapters as follows: (1)Canadian history of child protection, (2)definition of child abuse, (3)current situation of child protection in Canada, (4)outline of child protection and treatment, (5)triangular comparison of child protection and prevention in Canada, Australia and England. The first efforts at identifying and combating child abuse occurred in the latter part of the...

  19. The Speech Prevention in the Kindergarten

    OpenAIRE

    CHÁBEROVÁ, Lenka

    2017-01-01

    This thesis follows up the theme of logopaedics prevention and development of communication abilities. It introduce problematic of the most common speech disorders, development of communication skills, diagnostic of impaired verbal communication and development of grafomotorics in preschool age. It introduces practical exercises and techniques of speech correction in the sphere of the methodology of the prevention of impaired verbal communication. In practical part it maps development of impa...

  20. Jet lag prevention

    Science.gov (United States)

    ... medlineplus.gov/ency/patientinstructions/000719.htm Jet lag prevention To use the sharing features on this page, ... Headache Irritability Stomach upset Sore muscles Tips for Prevention Before your trip: Get plenty of rest, eat ...

  1. Research Areas: Prevention

    Science.gov (United States)

    NCI’s prevention research has a broad focus, from identifying environmental and lifestyle factors that influence cancer risk to studying the biology of how cancer develops and studying ways to disseminate prevention interventions.

  2. Marine Pollution Prevention Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Marine Pollution Prevention Act of 2008 implements the International Convention for the Prevention of Pollution from Ships, including related Protocols (MARPOL)...

  3. Preventing Type 2 Diabetes

    Science.gov (United States)

    ... Sexual & Urologic Problems Clinical Trials Preventing Type 2 Diabetes Perhaps you have learned that you have a ... I lower my chances of developing type 2 diabetes? Research such as the Diabetes Prevention Program shows ...

  4. Preventing Diabetes Problems

    Science.gov (United States)

    ... Problems Diabetes & Sexual & Urologic Problems Clinical Trials Preventing Diabetes Problems View or Print All Sections Heart Disease & ... prevent or delay sexual and urologic problems. Depression & Diabetes Depression is common among people with a chronic, ...

  5. Statins and Cancer Prevention

    Science.gov (United States)

    ... cell membrane integrity, cell signaling, protein synthesis, and cell cycle progression, all of which are potential areas of intervention to arrest the cancer process. What are the ... at the NCI Division of Cancer Prevention Web site at http://prevention. ...

  6. Preventing food poisoning

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/007441.htm Preventing food poisoning To use the sharing features on this page, please enable JavaScript. To prevent food poisoning , take the following steps when preparing food: Carefully ...

  7. Breast Cancer Prevention

    Science.gov (United States)

    ... of Breast & Gynecologic Cancers Breast Cancer Screening Research Breast Cancer Prevention (PDQ®)–Patient Version What is prevention? Go ... from starting. Risk-reducing surgery . General Information About Breast Cancer Key Points Breast cancer is a disease in ...

  8. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... Peer Counseling Blog About Media Donate Spinal Cord Injury Medical Expert Videos Topics menu Topics Preventing Pressure Sores Adult Injuries Spinal Cord Injury 101 David Chen, MD Preventing ...

  9. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... Injury Medical Expert Videos Topics menu Topics Preventing Pressure Sores Adult Injuries Spinal Cord Injury 101 David Chen, MD Preventing Pressure Sores Mary Zeigler, MS Transition from Hospital to ...

  10. Traditional preventive treatment options

    DEFF Research Database (Denmark)

    Longbottom, C; Ekstrand, K; Zero, D

    2009-01-01

    Preventive treatment options can be divided into primary, secondary and tertiary prevention techniques, which can involve patient- or professionally applied methods. These include: oral hygiene (instruction), pit and fissure sealants ('temporary' or 'permanent'), fluoride applications (patient...... options....

  11. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... L Sarah Harrison, OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury ... do to prevent pressure sores? play_arrow What role does diet and hydration play in preventing pressure ...

  12. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... to prevent pressure sores? play_arrow What is “skin tolerance” and how can it be ... play_arrow What role does diet and hydration play in preventing pressure sores among ...

  13. National Suicide Prevention Lifeline

    Science.gov (United States)

    ... Our Crisis Centers Stories of Hope and Recovery Mental Health & Suicide Prevention Glossary Get Involved Participate Our Crisis Centers Social Media Hub Promote National Suicide Prevention Month Providers & Professionals ...

  14. Prevention of gravitational collapse

    International Nuclear Information System (INIS)

    Moffat, J.W.; Taylor, J.G.

    1981-01-01

    We apply a new theory of gravitation to the question of gravitational collapse to show that collapse is prevented in this theory under very reasonable conditions. This result also extends to prevent ultimate collapse of the Universe. (orig.)

  15. Part C and Part D Compliance Actions

    Data.gov (United States)

    U.S. Department of Health & Human Services — This page includes results from CMSs Past Performance Review. The report called Spring 2014 Past Performance Review Outlier Results lists MA organizations and Part D...

  16. Accident prevention in radiotherapy.

    Science.gov (United States)

    Holmberg, O

    2007-04-01

    In order to prevent accidents in radiotherapy, it is important to learn from accidents that have occurred previously. Lessons learned from a number of accidents are summarised and underlying patterns are looked for in this paper. Accidents can be prevented by applying several safety layers of preventive actions. Categories of these preventive actions are discussed together with specific actions belonging to each category of safety layer.

  17. Accident prevention in radiotherapy

    OpenAIRE

    Holmberg, O

    2007-01-01

    In order to prevent accidents in radiotherapy, it is important to learn from accidents that have occurred previously. Lessons learned from a number of accidents are summarised and underlying patterns are looked for in this paper. Accidents can be prevented by applying several safety layers of preventive actions. Categories of these preventive actions are discussed together with specific actions belonging to each category of safety layer.

  18. Prevention of periodontal diseases.

    Science.gov (United States)

    Dentino, Andrew R; Kassab, Moawia M; Renner, Erica J

    2005-07-01

    The ultimate goal of periodontal disease prevention is to maintain the dentition over a lifetime in a state of health, comfort, and function in an aesthetically pleasing presentation. This article focuses on primary and secondary periodontal disease prevention as they relate to gingivitis and periodontitis. Risk assessment, mechanical plaque control, chemical plaque control, current clinical recommendations for optimal prevention, and future preventive strategies are discussed.

  19. Fall Prevention: Simple Tips to Prevent Falls

    Science.gov (United States)

    ... bars for the shower or tub A sturdy plastic seat for the shower or tub — plus a ... healthy-lifestyle/healthy-aging/in-depth/fall-prevention/art-20047358 . Mayo Clinic Footer Legal Conditions and Terms ...

  20. Chickenpox Prevention and Treatment

    Science.gov (United States)

    ... Multimedia Related Links Medline Plus Healthfinder.gov Shingles Prevention & Treatment Language: English Español (Spanish) Recommend on Facebook ... Prescribed by Your Doctor Español: Prevención y tratamiento Prevention The best way to prevent chickenpox is to ...

  1. Prevention IS Care

    Centers for Disease Control (CDC) Podcasts

    2009-03-26

    This podcast provides an overview of the Prevention IS Care campaign, which provides HIV prevention tools for medical care providers to use on a daily basis with patients who are living with HIV.  Created: 3/26/2009 by National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP).   Date Released: 3/26/2009.

  2. Strategies to prevent loneliness

    NARCIS (Netherlands)

    de Jong Gierveld, J.; Fokkema, T.; Sha'ked, A.; Rokach, A.

    2015-01-01

    Prevention is better than cure’. This also applies to loneliness experiences: preventing people from loneliness is better than helping them to reduce their feelings of loneliness through interventions. In this chapter, we argue the necessity of loneliness prevention strategies for handling future

  3. Prevention of Food Poisoning.

    Science.gov (United States)

    Army Quartermaster School, Ft. Lee, VA.

    The programed text provides a single lesson, four-hour, correspondence subcourse on the prevention of food poisoning. It covers the following areas: a definition of food poisoning; chemical food poisoning; biological food poisoning; causes and prevention of trichinosis; six factors controlling bacteria growth; bacterial infection; prevention of…

  4. Cancer risks and prevention

    International Nuclear Information System (INIS)

    Vessey, M.P.; Gray, M.

    1985-01-01

    A series of essays in honour of Sir Richard Doll is presented. Chapters cover the preventability of cancer, geography, smoking, diet, occupation, radiation, infections and immune impairment, exogenous and endogenous hormones, other drugs, prevention through legislation and by education and cancer risks and prevention in the Third World. The chapter on radiation has been indexed separately. (UK)

  5. Sunburn: Treatment and Prevention

    Science.gov (United States)

    ... 12 mos.) Toddler 1-3yrs. Preschool 3-5yrs Grade School 5-12yrs. Teen 12-18yrs. Young Adult 18-21yrs. Healthy Living Healthy Living Healthy Living Nutrition Fitness Sports Oral Health Emotional Wellness Growing Healthy Sleep Safety & Prevention Safety & Prevention Safety and Prevention Immunizations ...

  6. Comprehensive HIV Prevention for Transgender Persons.

    Science.gov (United States)

    Neumann, Mary Spink; Finlayson, Teresa J; Pitts, Nicole L; Keatley, JoAnne

    2017-02-01

    Transgender persons are at high risk for HIV infection, but prevention efforts specifically targeting these people have been minimal. Part of the challenge of HIV prevention for transgender populations is that numerous individual, interpersonal, social, and structural factors contribute to their risk. By combining HIV prevention services with complementary medical, legal, and psychosocial services, transgender persons' HIV risk behaviors, risk determinants, and overall health can be affected simultaneously. For maximum health impact, comprehensive HIV prevention for transgender persons warrants efforts targeted to various impact levels-socioeconomic factors, decision-making contexts, long-lasting protections, clinical interventions, and counseling and education. We present current HIV prevention efforts that reach transgender persons and present others for future consideration.

  7. Pollution prevention: The new environmental ethic

    International Nuclear Information System (INIS)

    Breen, J.J.; Dellarco, M.J.

    1991-01-01

    EPA is embarking on a new major environmental policy initiative: pollution prevention. It obviates the short-comings of end-of-pipe regulations and fosters efforts for industry to modify production practices to prevent pollution. For its part, the Agency has adopted this initiative in research and development, regulatory program development, and technology transfer activities. Research and Development programs are being established to address chemical substitution, reductions in chemical usage, product life cycles, and recycling. Regulatory programs are incorporating pollution prevention in major strategies of product stewardship and hazardous waste management. Technology transfer activities are designed to inform and educate industry and the public through Agency sponsored programs with the Pollution Prevention Information Center and the American Pollution Prevention Institute

  8. [Prevention of eating disorders].

    Science.gov (United States)

    Papežová, Hana

    2017-01-01

    The quality of the prevention of eating disorders represents in several last decades frequently discussed issue in the context of rapidly changing socio-economic conditions, a significant increase of influence of the media, new technologies and knowledge of risk factors. Primary prevention aims to reduce the risk of developing eating disorders, but secondary and tertiary prevention play the important role as well. Effective and coordinated prevention is still missing. Our experience of international cooperation of the last 20 years led to the development and evaluation of prevention programs. We are describing their fast development and ongoing programs following the new trends recommended by WHO.

  9. Prevention Of Stroke

    Directory of Open Access Journals (Sweden)

    Nagaraja D

    2005-01-01

    Full Text Available Stroke is an important cause for neurological morbidity and mortality. Prevention of ischemic stroke involves identification and prevention of risk factors and optimal use of pharmacotherapy. Risk factors have been classified as modifiable and non-modifiable; control of modifiable factors should prevent stroke occurrence. Stroke prevention has been described at three levels: primary, secondary and tertiary. Prolonged hypertension increases an individual′s risk for developing fatal or nonfatal stroke by three times and its control has been shown to prevent stroke. Diabetes mellitus is an important cause for microangiopathy and predisposes to stroke. Statin trials have shown significant reduction in stroke in those who were treated with statins. Stroke risk can be reduced by avoiding tobacco use, control of obesity and avoiding sedentary life style. Anti platelet medications are effective for secondary prevention of stroke. Educating society regarding modifiable risk factors and optimal use of pharmacotherapy form the cornerstone for the prevention of stroke.

  10. Prevention of suicide

    Directory of Open Access Journals (Sweden)

    Rajiv Gupta

    2017-01-01

    Full Text Available Suicide is a major public health problem in India, probably even bigger than in the West. Suicidal behavior is the best conceptualized as a multifaceted complex problem involving social factors and mental illnesses. Broadly, there are two approaches to suicide prevention; population preventive strategies and high-risk preventive strategies. Population preventive strategies include reducing availability of means for suicide, education of primary care physicians, influencing media portrayal of suicidal behavior, education of the public, telephone helplines, and addressing economic issues associated with suicidal behavior. High-risk preventive strategy includes identifying individuals with high risk of committing suicide, intensively treating mental illness if present, and providing psychosocial support. Thus, prevention requires a multipronged effort with collaboration from various sectors including mental health professionals, social justice department, and macroeconomic policy makers.

  11. Traditional preventive treatment options

    DEFF Research Database (Denmark)

    Longbottom, C; Ekstrand, K; Zero, D

    2009-01-01

    conventional operative care, and since controlling the caries process prior to first restoration is the key to breaking the repair cycle and improving care for patients, future research should address the shortcomings in the current level of supporting evidence for the various traditional preventive treatment......Preventive treatment options can be divided into primary, secondary and tertiary prevention techniques, which can involve patient- or professionally applied methods. These include: oral hygiene (instruction), pit and fissure sealants ('temporary' or 'permanent'), fluoride applications (patient...

  12. Prevention of Prosthetic Dentistry

    Directory of Open Access Journals (Sweden)

    Eremin O.V.

    2011-03-01

    Full Text Available Prevention in prosthetic dentistry is not just a regular oral hygiene and the prevention of caries in the early stages of its development. The initial goal of orthopedic and dental should be the ability to convey to the patient's sense of pros-thetics that proteziruya one saved more. An example is included prosthetic dental arch defects with bridges or single artificial crowns on implants that will prevent movement of teeth and the continuity of the dentition

  13. Prevent Infections During Chemotherapy

    Centers for Disease Control (CDC) Podcasts

    2011-10-24

    This podcast discusses the importance of preventing infections in cancer patients who are undergoing chemotherapy. Dr. Lisa Richardson, CDC oncologist, talks about a new Web site for cancer patients and their caregivers.  Created: 10/24/2011 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP), Division of Cancer Prevention and Control (DCPC).   Date Released: 10/24/2011.

  14. Speech disorder prevention

    Directory of Open Access Journals (Sweden)

    Miladis Fornaris-Méndez

    2017-04-01

    Full Text Available Language therapy has trafficked from a medical focus until a preventive focus. However, difficulties are evidenced in the development of this last task, because he is devoted bigger space to the correction of the disorders of the language. Because the speech disorders is the dysfunction with more frequently appearance, acquires special importance the preventive work that is developed to avoid its appearance. Speech education since early age of the childhood makes work easier for prevent the appearance of speech disorders in the children. The present work has as objective to offer different activities for the prevention of the speech disorders.

  15. Work hazard prevention plans

    International Nuclear Information System (INIS)

    Albertos Campos, F.

    2009-01-01

    The prevention of industrial risks is a constantly evolving discipline that has changed considerable in the last 25 years. The Cofrentes Nuclear Power Plants has always been operated with a clear policy favoring prevention by supporting the principle of its integration, i. e., that the hierarchical functional organization of the company make sure that industrial risk prevention is effective and that health and safety standards are met. The historical evolution of occupational safety in the Cofrentes Nuclear Power Plant shows a a clear trend towards improvement and is the results of many years of hard work and effort by the plants own and contractor personnel in the field of industrial risk prevention. (Author)

  16. Fungus Infections: Preventing Recurrence

    Science.gov (United States)

    ... Favorite Name: Category: Share: Yes No, Keep Private Fungus Infections: Preventing Recurrence Share | Doctors have excellent treatments for skin fungus infections that occur on the feet, nails, groin, ...

  17. Economic evaluation of prevention; further evidence

    NARCIS (Netherlands)

    Wit GA de; Verweij A; Baal PHM van; Vijgen SMC; Berg M van den; Busch MCM; Barnhoorn MJM; Schuit AJ; Wit GA de; Schuit AJ; Berg M van den; ZonMw; VTV; PZO

    2007-01-01

    This report is the third in a series of reports that aim to identify cost-effective preventive interventions that have not yet been diffused into the Dutch health care system or into a public health setting. In the first part of this report, five new interventions are presented and at the same time,

  18. Community Based Crime Prevention in Guatemala | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Community Based Crime Prevention in Guatemala. Guatemala is one of the most violent countries in the world. Guatemalans of every age, class and ethnicity confront violence daily in every part of the national territory. According to statistics kept by the police and the human rights ombudsman, Guatemala registered 3 366 ...

  19. Future Directions in Preventing Child Abuse.

    Science.gov (United States)

    Krugman, Richard D.

    1995-01-01

    Efforts to prevent the abuse and neglect of children requires: professionals and citizens who care to make a difference; development of multidisciplinary units, teams, or organizations to deal with specific parts of the problem; a clear statement of child protection policy; programs that work; commitment to research and program evaluation; and a…

  20. Stroke Prevention Trials in Sickle Cell Anemia

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2006-06-01

    Full Text Available As part of an International Pediatric Stroke Study launched in 2002, the Stroke Prevention Trial in Sickle Cell Anemia (STOP reports a reduction in the number of overt clinical strokes in children with critically high transcranial Doppler velocities (>200 cm/sec who were regularly transfused.

  1. Prevention at Community Colleges. Prevention Update

    Science.gov (United States)

    Higher Education Center for Alcohol, Drug Abuse, and Violence Prevention, 2012

    2012-01-01

    According to "Community College Student Alcohol Use: Developing Context-Specific Evidence and Prevention Approaches," community colleges have traditionally had a threefold mission that includes preparing students for transfer to four-year colleges, developmental education, and workforce preparation. The researchers point out that the demographic…

  2. Court won't hear State claims as part of worker's ADA suit.

    Science.gov (United States)

    1997-09-19

    The 11th U.S. Circuit Court of Appeals cannot overturn a Federal judge's refusal to hear the State-law sexual harassment claims brought as part of an Americans with Disabilities Act (ADA) suit. [Name removed] filed Federal and State charges against Checkers drive-in restaurants. [Name removed] claims he was subjected to offensive and sexually exploitive language and was ridiculed as gay and having AIDS by one of his supervisors. According to [name removed], a separate supervisor pressured him to have sex and subjected him to physical contact. When [name removed] was fired, he filed an eight-count complaint under Federal and State law. He alleged that Checkers violated the Americans with Disabilities Act (ADA) because his supervisors believed he was HIV-positive and discriminated against him intentionally on that basis. He also sought recovery under the Florida AIDS discrimination statute and the Florida Civil Rights Act. The Federal judge decided not to handle the State-law claims and the 11th Circuit Court of Appeals refused to act on [name removed]'s appeal. Now [name removed] may have to choose either a Federal or a State court to hear all of his claims.

  3. Diagonals part one

    OpenAIRE

    van de Rakt, Jan; McCarthy-Grunwald, Steven

    2015-01-01

    The diagonals are muscle structures that hold and moves our body. In this article (part one) we explore the development of these diagonals from childhood and the enhancement of them in professional athletes Part two will then explore what happens when neurological diseases damage these muscle pattern. Neurological disease will affect how the diagonals work more than orthopedic diseases, due to its dependency on structures within the brain. Although these parts of the brain are not yet identif...

  4. Standard biological parts knowledgebase.

    Science.gov (United States)

    Galdzicki, Michal; Rodriguez, Cesar; Chandran, Deepak; Sauro, Herbert M; Gennari, John H

    2011-02-24

    We have created the Knowledgebase of Standard Biological Parts (SBPkb) as a publically accessible Semantic Web resource for synthetic biology (sbolstandard.org). The SBPkb allows researchers to query and retrieve standard biological parts for research and use in synthetic biology. Its initial version includes all of the information about parts stored in the Registry of Standard Biological Parts (partsregistry.org). SBPkb transforms this information so that it is computable, using our semantic framework for synthetic biology parts. This framework, known as SBOL-semantic, was built as part of the Synthetic Biology Open Language (SBOL), a project of the Synthetic Biology Data Exchange Group. SBOL-semantic represents commonly used synthetic biology entities, and its purpose is to improve the distribution and exchange of descriptions of biological parts. In this paper, we describe the data, our methods for transformation to SBPkb, and finally, we demonstrate the value of our knowledgebase with a set of sample queries. We use RDF technology and SPARQL queries to retrieve candidate "promoter" parts that are known to be both negatively and positively regulated. This method provides new web based data access to perform searches for parts that are not currently possible.

  5. Controlled parts management

    International Nuclear Information System (INIS)

    Boyle, C.M.; Hidalgo, S.P.; Martinez, B.J.

    2004-01-01

    The Controlled Parts Management (CPM) system is based on industry standard practices for managing inventory. CPM is designed to record the movement of any type of inventory in a defined region referred to as an Account or SubAccount. The system is used to track the receiving, processing, storing and transfer of inventory parts. CPM provides information on parts, quantity and the exact location of the inventory. CPM is a barcode-based-part tracking system currently used to track controlled parts that are used in the R and D and testing of weapons; this tracking helps maintain the part pedigree that is required for certification of a weapon or weapon test. CPM includes bar code data collection software programmed into portable bar code readers for automating physical inventory services and remote transaction capture. CPM interfaces to other Engineering systems and supports a 'material content' of a weapons test through the test Bill of Materials and assignment of a unique inventory part in CPM. Additional functionality includes the ability to group or join parts, logically or physically and temporary or permanent, to represent discrete parts, containers, subassemblies and assemblies, and groupings.

  6. Standard biological parts knowledgebase.

    Directory of Open Access Journals (Sweden)

    Michal Galdzicki

    2011-02-01

    Full Text Available We have created the Knowledgebase of Standard Biological Parts (SBPkb as a publically accessible Semantic Web resource for synthetic biology (sbolstandard.org. The SBPkb allows researchers to query and retrieve standard biological parts for research and use in synthetic biology. Its initial version includes all of the information about parts stored in the Registry of Standard Biological Parts (partsregistry.org. SBPkb transforms this information so that it is computable, using our semantic framework for synthetic biology parts. This framework, known as SBOL-semantic, was built as part of the Synthetic Biology Open Language (SBOL, a project of the Synthetic Biology Data Exchange Group. SBOL-semantic represents commonly used synthetic biology entities, and its purpose is to improve the distribution and exchange of descriptions of biological parts. In this paper, we describe the data, our methods for transformation to SBPkb, and finally, we demonstrate the value of our knowledgebase with a set of sample queries. We use RDF technology and SPARQL queries to retrieve candidate "promoter" parts that are known to be both negatively and positively regulated. This method provides new web based data access to perform searches for parts that are not currently possible.

  7. Loose part monitoring device

    International Nuclear Information System (INIS)

    Nomura, Hiroshi.

    1992-01-01

    The device of the present invention estimates a place where loose parts occur and structural components as the loose parts in a fluid flow channel of a reactor device, to provide information thereof to a plant operator. That is, the device of the present invention comprises (1) a plurality of detectors disposed to each of equipments constituting fluid channels, (2) an abnormal sound sensing device for sensing signals from the detectors, (3) an estimation section for estimating the place where the loose parts occur and the structural components thereof based on the signals sensed by the abnormal sound sensing section, (4) a memory section for storing data of the plant structure necessary for the estimation, and (5) a display section for displaying the result of the estimation. In such a device, the position where the loose parts collide against the plant structural component and the energy thereof are estimated. The dropping path of the loose parts is estimated from the estimation position. Parts to be loose parts in the path are listed up. The parts on the list is selected based on the estimated energy thereby enabling to determine the loose parts. (I.S.)

  8. Top event prevention in complex systems

    International Nuclear Information System (INIS)

    Youngblood, R.W.; Worrell, R.B.

    1995-01-01

    A key step in formulating a regulatory basis for licensing complex and potentially hazardous facilities is identification of a collection of design elements that is necessary and sufficient to achieve the desired level of protection of the public, the workers, and the environment. Here, such a collection of design elements will be called a ''prevention set.'' At the design stage, identifying a prevention set helps to determine what elements to include in the final design. Separately, a prevention-set argument could be used to limit the scope of regulatory oversight to a subset of design elements. This step can be taken during initial review of a design, or later as part of an effort to justify relief from regulatory requirements that are burdensome but provide little risk reduction. This paper presents a systematic approach to the problem of optimally choosing a prevention set

  9. Essentials of periodontal medicine in preventive medicine

    Directory of Open Access Journals (Sweden)

    Minkle Gulati

    2013-01-01

    Full Text Available Influence of systemic disorders on periodontal diseases is well established. However, of growing interest is the effect of periodontal diseases on numerous systemic diseases or conditions like cardiovascular disease, cerebrovascular disease, diabetes, pre-term low birth weight babies, preeclampsia, respiratory infections and others including osteoporosis, cancer, rheumatoid arthritis, erectile dysfunction, Alzheimer′s disease, gastrointestinal disease, prostatitis, renal diseases, which has also been scientifically validated. This side of the oral-systemic link has been termed Periodontal Medicine and is potentially of great public health significance, as periodontal disease is largely preventable and in many instances readily treatable, hence, providing many new opportunities for preventing and improving prognosis of several systemic pathologic conditions. This review article highlights the importance of prevention and treatment of periodontal diseases as an essential part of preventive medicine to circumvent its deleterious effects on general health.

  10. Preventing Eye Injuries

    Science.gov (United States)

    ... Stories Español Eye Health / Eye Health A-Z Eye Injuries Sections Preventing Eye Injuries Recognizing and Treating ... Infographic Five Steps to Safer Champagne Celebrations Preventing Eye Injuries Leer en Español: Lesiones de los ojos ...

  11. HIV Risk and Prevention

    Science.gov (United States)

    ... Prevention VIH En Español Get Tested Find an HIV testing site near you. Enter ZIP code or city Follow HIV/AIDS CDC HIV CDC HIV/AIDS See RSS | ... Email Updates on HIV Syndicated Content Website Feedback HIV Risk and Prevention Recommend on Facebook Tweet Share ...

  12. Preventative Medicine today

    Directory of Open Access Journals (Sweden)

    José Antonio Maluf de Carvalho

    2005-03-01

    Full Text Available The great majority of chronic diseases can be prevented byreducing risks, understood as factors that increase the probabilityof a specific disease or condition, such as hypertension,hypercholesterolemia, inadequate diet, smoking habit, obesity andsedentarism. These aspects are evaluated in this article as wellas prevention and screening methods.

  13. [Prevention of psychosocial risks].

    Science.gov (United States)

    Dalle, Édouard; Trichard-Salembier, Alexandra; Sobaszek, Annie

    2018-02-01

    The theme of psychosocial risks remains in the workplace. It is therefore essential that all members of a company are made aware of the terminology and specific prevention actions in this field. Distinguishing between the manifestations of these risks and their causes and consequences helps to improve prevention. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  14. Prevention de la Poliomyelite

    Directory of Open Access Journals (Sweden)

    M. Baltazard

    1962-01-01

    Full Text Available In Iran, the prevention of poliomyelitis is practically limited to vaccinatton This paper, however, gives a detailed account of the preventive measures attempting to check the spread of the infection and of those aiming at the reduction of the frequency of the paralytic manifestation

  15. Cancer Prevention Overview (PDQ)

    Science.gov (United States)

    ... have been shown to reduce the risk of breast cancer in women at high risk. SERMS may cause side effects , such as hot flashes , so they are not often used for prevention of cancer. See the PDQ summary on Breast Cancer Prevention for more information. Finasteride has been ...

  16. Prevent Cervical Cancer!

    Centers for Disease Control (CDC) Podcasts

    2015-01-08

    Cervical cancer can be prevented. Listen as two friends—one a doctor—talk about screening tests and early detection. Learn what test you might need.  Created: 1/8/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 1/8/2015.

  17. Prevention of Preeclampsia

    Directory of Open Access Journals (Sweden)

    Sammya Bezerra Maia e Holanda Moura

    2012-01-01

    Full Text Available Preeclampsia (PE affects around 2–5% of pregnant women. It is a major cause of maternal and perinatal morbidity and mortality. In an attempt to prevent preeclampsia, many strategies based on antenatal care, change in lifestyle, nutritional supplementation, and drugs have been studied. The aim of this paper is to review recent evidence about primary and secondary prevention of preeclampsia.

  18. Prevention of Preeclampsia

    OpenAIRE

    Bezerra Maia e Holanda Moura, Sammya; Marques Lopes, Laudelino; Murthi, Padma; da Silva Costa, Fabricio

    2012-01-01

    Preeclampsia (PE) affects around 2–5% of pregnant women. It is a major cause of maternal and perinatal morbidity and mortality. In an attempt to prevent preeclampsia, many strategies based on antenatal care, change in lifestyle, nutritional supplementation, and drugs have been studied. The aim of this paper is to review recent evidence about primary and secondary prevention of preeclampsia.

  19. Can I Prevent Acne?

    Science.gov (United States)

    ... for Educators Search English Español Can I Prevent Acne? KidsHealth / For Teens / Can I Prevent Acne? Print en español ¿Puedo prevenir el acné? What Causes Acne? Contrary to what you may have heard, acne ...

  20. 75 FR 31837 - Petition for Exemption From the Vehicle Theft Prevention Standard; Mercedes-Benz

    Science.gov (United States)

    2010-06-04

    ... National Highway Traffic Safety Administration Petition for Exemption From the Vehicle Theft Prevention... likely to be as effective in reducing and deterring motor vehicle theft as compliance with the parts... exemption from parts- marking pursuant to 49 CFR part 543, Exemption from Vehicle Theft Prevention Standard...

  1. Prevention of preterm birth.

    LENUS (Irish Health Repository)

    Flood, Karen

    2012-02-01

    Preterm birth (delivery before 37 completed weeks of gestation) is common and rates are increasing. In the past, medical efforts focused on ameliorating the consequences of prematurity rather than preventing its occurrence. This approach resulted in improved neonatal outcomes, but it remains costly in terms of both the suffering of infants and their families and the economic burden on society. Increased understanding of the pathophysiology of preterm labor has altered the approach to this problem, with increased focus on preventive strategies. Primary prevention is a limited strategy which involves public education, smoking cessation, improved nutritional status and avoidance of late preterm births. Secondary prevention focuses on recurrent preterm birth which is the most recognisable risk factor. Widely accepted strategies include cervical cerclage, progesterone and dedicated clinics. However, more research is needed to explore the role of antibiotics and anti-inflammatory treatments in the prevention of this complex problem.

  2. Preventing eating disorders.

    Science.gov (United States)

    Shaw, Heather; Stice, Eric; Becker, Carolyn Black

    2009-01-01

    This article reviews eating disorder (ED) prevention programs, highlighting features that define successful programs and particularly promising interventions, and how they might be further refined. The field of ED prevention has advanced considerably both theoretically and methodologically compared with the earlier ED prevention programs, which were largely psychoeducational and met with limited success. Recent meta-analytic findings show that more than half (51%) of ED prevention interventions reduced ED risk factors and more than a quarter (29%) reduced current or future eating pathology (EP). A couple of brief programs have been shown to reduce the risk for future onset of EP and obesity. Selected interactive, multisession programs offered to participants older than 15 years, delivered by professional interventionists and including body acceptance or dissonance-induction content, produced larger effects. Understanding and applying these results can help inform the design of more effective prevention programs in the future.

  3. Prevention of choking among children.

    Science.gov (United States)

    2010-03-01

    Program of the CPSC should be modified to conduct more-detailed surveillance of choking on food among children. Food manufacturers should design new foods and redesign existing foods to avoid shapes, sizes, textures, and other characteristics that increase choking risk to children, to the extent possible. Pediatricians, dentists, and other infant and child health care providers should provide choking-prevention counseling to parents as an integral part of anticipatory guidance activities.

  4. Prevenção a Fraudes em Empresas Industriais de Autopeças na Região do ABCFraud Prevention in the Auto Parts Industry in the ABC RegionPrevención de Fraudes en Empresas Industriales de Autopiezas en la Región del ABC

    Directory of Open Access Journals (Sweden)

    OLIVA, Eduardo de Camargo

    2006-09-01

    Full Text Available RESUMONos últimos anos, os casos de fraudes têm ocupado os meios de comunicação. O que pode contribuir para esta situação é a velocidade das mudanças no ambiente organizacional e os controles internos não estarem conseguindo acompanhar a mesma velocidade, aumentando assim o potencial de práticas de atos ilícitos. Por outro lado, o avanço tecnológico contribui para a informatização, possibilitando melhoria na detecção das fraudes. Esta investigação se propôs a verificar como as empresas praticam a prevenção às fraudes e, para tanto, efetuou-se um levantamento de campo junto as empresas de auto-peças da região do ABC a partir de um critério de estratificação tendo por base a lista do Sindipeças. Como resultado verificou-se que são utilizados alguns controles internos. Porém, o assunto fraude ainda não é tratado com a transparência e cuidados necessários e as empresas necessitariam incorporá-lo como risco inerente ao negócio.ABSTRACTFor many years the fraud cases have been occupying the communication means. One fact that could contribute for this situation are the changes in the organizations are quick and the internal controls tend not follow the same quickness, increasing the practice potential of illicit acts. On the other hand, the technological improvement contributes for information technology, which improves the fraud detection. This investigation had as purpose to verify how the companies practice fraud prevents. For that, it was done a search in some automobile part companies in the ABC region. It was used the stratification criterion, using as basis the Sindipeças list. As result, it was verified that the companies use some internal For many years the fraud cases have been occupying the communication means. One fact that could contribute for this situation are that the changes in the organizations are quick and the internal controls tend not follow the same quickness, increasing the potential practice

  5. Play your part

    CERN Document Server

    Ramsey, Gaynor

    1978-01-01

    Play your part is a collection of then situations in which students have to take on the roles of particular people and express their opinions, feelings or arguments about the situation. Play your part is intended for use with advanced students of English.

  6. Introduction to Part 3

    DEFF Research Database (Denmark)

    Petersen, Nils Holger

    2015-01-01

    A brief contextualising discussion of Western Music History and its relations to Theological Aesthetical Thought since Carolingian Times as an introduction to 3 music articles in Part 3 of the volume.......A brief contextualising discussion of Western Music History and its relations to Theological Aesthetical Thought since Carolingian Times as an introduction to 3 music articles in Part 3 of the volume....

  7. Chicken feet: Part two.

    Science.gov (United States)

    Kessel, D F

    1997-08-01

    This article is the second part of the story of a trip taken by the author to Guatemala, Central America in 1996. It was a part of Operation Kids, which is sponsored by the Christian Children's Fund in Richmond, VA. The author and her fellow medical staff represented the Plastic Surgery Division of the Medical College of Virginia Hospitals.

  8. Homelessness as social and individual problem – possibilities and prevention

    Directory of Open Access Journals (Sweden)

    Małgorzata Piechowicz

    2012-12-01

    Full Text Available This article consists of several parts. The first part includes definitional considerations over the notion of homelessness. It also describes social situation of the homeless, whereas the second part concentrates on both the analysis of causes and effects of homelessness and on the attempt to show the scale of this phenomenon. The last part of the article focuses on the prevention of homelessness. It emphasizes the importance of interdisciplinarity of preventive and compensatory actions in the scope of the discussed phenomenon.

  9. Track buckling prevention : theory, safety concepts, and applications

    Science.gov (United States)

    2013-03-31

    This report is a part of the John A. Volpe National Transportation Systems Centers Track Stability Research Program for the Federal Railroad Administration on thermal buckling of continuous welded rail (CWR) track and its prevention. Presented in ...

  10. STD Prevention Policies in the United States: Evidence and Opportunities

    OpenAIRE

    Leichliter, Jami S.; Seiler, Naomi; Wohlfeiler, Dan

    2016-01-01

    Policies are an important part of public health interventions, including in the area of STD prevention. Similar to other tools used in public health, policies are often evaluated to determine their usefulness. Therefore, we conducted a non-systematic review of policy evidence for sexually transmitted disease prevention. Our review considers assessments or evaluations of STD prevention-specific policies, health care system policies, and other, broader policies that have the potential to impact...

  11. Child Prostitucion in the Czech Republic and the Prevention

    OpenAIRE

    Mašitová, Tereza

    2014-01-01

    The thesis focuses on child prostitution and its prevention. Firstly, the reader is informed about the basic knowledge of the phenomenon of child prostitution and the phenomenon which the prostitution is a part of, namely commercial sexual children abuse. The thesis describes possible causes and consequences and big part of it is dedicated to the prevention where also the legal aspects of prostitution are described. The objective of the thesis is to find out how are the children, ninth grade ...

  12. Method for preventing micromechanical structures from adhering to another object

    Science.gov (United States)

    Smith, J.H.; Ricco, A.J.

    1998-06-16

    A method for preventing micromechanical structures from adhering to another object includes the step of immersing a micromechanical structure and its associated substrate in a chemical species that does not stick to itself. The method can be employed during the manufacture of micromechanical structures to prevent micromechanical parts from sticking or adhering to one another and their associated substrate surface. 3 figs.

  13. tanzania danida dental health programme progress in prevention

    African Journals Online (AJOL)

    The third sector we need to examine ~ garding progress in prevention is the activities of the dental profeSSionals themselves. As part of the continuing education programme, all dental assistants have attended a workshop' on epidemiology, health education and planning of preventive programmes. They accepted this new.

  14. Integrated Models of School-Based Prevention: Logic and Theory

    Science.gov (United States)

    Domitrovich, Celene E.; Bradshaw, Catherine P.; Greenberg, Mark T.; Embry, Dennis; Poduska, Jeanne M.; Ialongo, Nicholas S.

    2010-01-01

    School-based prevention programs can positively impact a range of social, emotional, and behavioral outcomes. Yet the current climate of accountability pressures schools to restrict activities that are not perceived as part of the core curriculum. Building on models from public health and prevention science, we describe an integrated approach to…

  15. 46 CFR 131.935 - Prevention of oil pollution.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Prevention of oil pollution. 131.935 Section 131.935... Miscellaneous § 131.935 Prevention of oil pollution. Each vessel must be operated in compliance with— (a) Section 311 of the Federal Water Pollution Control Act, as amended (33 U.S.C. 1321); and (b) 33 CFR parts...

  16. Impact of health education on home treatment and prevention

    African Journals Online (AJOL)

    Emmanuel Ameh

    Impact of health education on home treatment and prevention of malaria. Chirdan O. O. et al. Page | 115 taken at home and dangers of self treatment. Part 3: Treatment of uncomplicated malaria and prevention of malaria. Posters and chloroquine drug charts were used as teaching aids. Post intervention impact assessment.

  17. Prevention in practice

    DEFF Research Database (Denmark)

    Birch, Stephen; Bridgman, Colette; Brocklehurst, Paul

    2015-01-01

    for the conference, collected materials from scribes during the conference and additional resources collated in advance of the meeting, authors agreed on the summary document. RESULTS: The Prevention in Practice conference aimed to collate information about which diseases could be prevented in practice, how diseases...... could be identified early enough to facilitate prevention, what evidence based therapies and treatments were available and how, given the collective evidence, could these be introduced in general dental practice within different reimbursement models. CONCLUSIONS: While examples of best practice were...

  18. CSI cardiac prevent 2015

    Directory of Open Access Journals (Sweden)

    S Ramakrishnan

    2015-01-01

    Full Text Available The CSI Cardiac Prevent 2015 was held at Hotel Taj Palace, New Delhi, on September 25-27, 2015. The major challenge was to create interest among cardiologists and physicians on preventive cardiology, a neglected area. The theme of the conference was "Innovations in Heart Disease Prevention.′′ This conference included "CSI at WHF Roadmap Workshop, Inauguration Ceremony, scientific program, plenary sessions, Nursing/Dietician track, Industry Exhibition, Social Events," Great India blood pressure Survey, and CSI Smart Heart App. A total of 848 delegates/faculties attended this conference against a total of 1140 people registered for the meeting.

  19. Obesity Prevention and Screening.

    Science.gov (United States)

    Mackey, Eleanor R; Olson, Alexandra; DiFazio, Marc; Cassidy, Omni

    2016-03-01

    Obesity is widespread, associated with several physical and psychosocial comorbidities, and is difficult to treat. Prevention of obesity across the lifespan is critical to improving the health of individuals and society. Screening and prevention efforts in primary care are an important step in addressing the obesity epidemic. Each period of human development is associated with unique risks, challenges, and opportunities for prevention and intervention. Screening tools for overweight/obesity, although imperfect, are quick and easy to administer. Screening should be conducted at every primary care visit and tracked longitudinally. Screening tools and cutoffs for overweight and obesity vary by age group. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Prevention of Eye Injuries

    OpenAIRE

    Pashby, Tom

    1981-01-01

    In Canada 30,000 people are registered as blind; in one third of these, blindness might have been avoided. Prevention is the key to reducing the number of eye injuries and blind eyes. The role of the family physician in early identification of treatable conditions and in the education of patients is discussed, but responsibility for prevention belongs to all physicians. The success of prevention is seen in the great reduction in eye injuries in industry and sports since eye protectors have be...

  1. Measuring pollution prevention

    International Nuclear Information System (INIS)

    Stephan, D.G.; Bridges, J.S.

    1992-01-01

    To assess progress in pollution prevention, estimates or measurements of the amounts of pollution actually prevented have to be made. Such estimates or measurements tell us how far we have come and, possibly, how much farther there is to go in utilizing pollution prevention as a tool for improving environmental quality. They can, theoretically, be used to assess progress on a scale ranging from the individual facility or even the individual process or activity generation wastes to scale as large as a geographical area such as a county, a state or even the United States as a whole. 3 refs

  2. Novel preventive treatment options

    DEFF Research Database (Denmark)

    Longbottom, C; Ekstrand, K; Zero, D

    2009-01-01

    A number of novel preventive treatment options which, as with traditional methods, can be differentiated into 3 categories of prevention (primary, secondary and tertiary), have been and are being currently investigated. Those reviewed are either commercially available or appear relatively close...... of these techniques show considerable promise and dentists should be aware of these developments and follow their progress, the evidence for each of these novel preventive treatment options is currently insufficient to make widespread recommendations. Changes in dental practice should be explored to see how oral...

  3. Can Vaginitis Be Prevented?

    Science.gov (United States)

    ... examples of safe sex. 1 Centers for Disease Control and Prevention. (2010). Self-study STD module—vaginitis . ... Halvorson New Chief of Gynecologic Health and Disease Branch Division of Epidemiology, Statistics, ...

  4. Dental Sealants Prevent Cavities

    Science.gov (United States)

    ... FAQs CDC SEALS Software CDC State Strategies: Preventing Tooth Decay CDC Oral Health Data Other Sites MedlinePlus – Child Dental Health MedlinePlus – Tooth Decay American Dental Association – Evidence-based clinical practice guideline ...

  5. Prevent Back Pain

    Science.gov (United States)

    ... and prevent back pain: Do back-strengthening and stretching exercises at least 2 or 3 times a week. ... risk of back pain. Do back-strengthening and stretching exercises [PDF - 244 KB] at least 2 or 3 ...

  6. Preventing Knee Injuries

    Science.gov (United States)

    ... Blog Skip breadcrumb navigation Preventing Knee Injuries Knee injuries in children and adolescent athletes may be the result of ... occur in childhood sports, but with any knee injury in a growing child there is a possibility of a fracture related ...

  7. Home Improvements Prevent Falls

    Science.gov (United States)

    ... turn JavaScript on. Feature: Falls and Older Adults Home Improvements Prevent Falls Past Issues / Winter 2014 Table ... and ensure your safety. "Safe-ty-fy" Your Home Some Questions for Your Provider Will my medicines ...

  8. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... increased? play_arrow What do family members and caregivers need to know about pressure sores? play_arrow What do family members and caregivers need to do to prevent pressure sores? play_ ...

  9. Prostate Cancer Prevention

    Science.gov (United States)

    ... prostate cancer A man whose father, brother, or son has had prostate cancer has a higher-than- ... known if these drugs lower the risk of death from prostate cancer. The Prostate Cancer Prevention Trial ( ...

  10. Prevention of cisplatin nephrotoxicity

    Directory of Open Access Journals (Sweden)

    Hayati Fatemeh

    2016-01-01

    Full Text Available Cisplatin has a well-established role in the treatment of broad spectrum of malignancies; however its use is limited because of cisplatin-induced nephrotoxicity (CIN which can be progressive in more than 50% of cases. The most important risk factors for CIN include higher doses of cisplatin, previous cisplatin chemotherapy, underlying kidney damage and concurrent treatment with other potential nephrotoxin agents, such as aminoglycosides, nonsteroidal anti-inflammatory agents, or iodinated contrast media. Different strategies have been offered to diminish or prevent nephrotoxicity of cisplatin. The standard approach for prevention of CIN is the administration of lower doses of cisplatin in combination with full intravenous hydration prior and after cisplatin administration. Cisplatin-induced oxidative stress in the kidney may be prevented by natural antioxidant compounds. The results of this review show that many strategies for prevention of CIN exist, however, attention to the administration of these agent for CIN is necessary.

  11. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... About Media Donate Spinal Cord Injury Medical Expert Videos Topics menu Topics Preventing Pressure Sores Adult Injuries ... LLC Understanding Spinal Cord Injury About Us Expert Videos Contact Us Personal Experience Videos Blog Videos By ...

  12. Preventing Financial Crime

    DEFF Research Database (Denmark)

    Boll, Karen

    This paper investigates the Swedish tax authority’s (Skatteverkets) compliance initiative called Preventing Financial Crime. In Sweden tax evasion related to organised moon-lighting is defined as a major risk to the revenue collection and to the legitimacy of Skatteverket. The traditional approach...... to abating such tax evasion has been reformed and a new mix-method approach adopted. This approach combines a proactive strategy—Preventing Financial Crime—with a reactive inspection strategy. During one a month of intensive fieldwork in Sweden, I studied the daily work in Preventing Financial Crime. Based...... on this, the paper shows that the Swedish tax officials seek to motivate large construction contractors and municipalities to take preventive measures in relation to their sub-contractors to avoid and abate tax evasion. The paper shows the challenges in engaging and involving these external stakeholders...

  13. Oral Cancer Prevention

    Science.gov (United States)

    ... Cancer Diagnosis Prevention Screening & Early Detection Treatment Cancer & Public Health Cancer Health Disparities Childhood Cancer Clinical Trials Global Health Key Initiatives Cancer Moonshot Genomic Data Commons National Clinical Trials ...

  14. Esophageal Cancer Prevention

    Science.gov (United States)

    ... Cancer Diagnosis Prevention Screening & Early Detection Treatment Cancer & Public Health Cancer Health Disparities Childhood Cancer Clinical Trials Global Health Key Initiatives Cancer Moonshot Genomic Data Commons National Clinical Trials ...

  15. Child Maltreatment Prevention

    Science.gov (United States)

    ... Study Prevent Shaken Baby Syndrome Suggested Practices for Journalists Reporting on Child Abuse and Neglect [PDF 2. ... input class="button submit" name="commit" type="submit" value="Submit" /> Related Links Saving Lives & Protecting People ...

  16. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... Counseling Blog About Media Donate Spinal Cord Injury Medical Expert Videos Topics menu Topics Preventing Pressure Sores ... sores? What is a Spinal Cord Injury? SCI Medical Experts People Living With SCI Personal Experiences By ...

  17. Prevent Child Abuse America

    Science.gov (United States)

    ... call the police . Crisis and support contacts For Child Abuse Reporting Numbers in your State please visit: Child ... suspected child abuse and neglect. Parent Resources Prevent Child Abuse America (800) CHILDREN A resource for tips, referrals, ...

  18. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... Adult Injuries Spinal Cord Injury 101 David Chen, MD Preventing Pressure Sores Mary Zeigler, MS Transition from ... Rosenberg, PsyD Understanding SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa ...

  19. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... hours? play_arrow What's the best way to do daily skin inspections? play_arrow What are the ... for someone with a spinal cord injury to do to prevent pressure sores? play_arrow Why is ...

  20. Wildfire Prevention Strategies.

    Science.gov (United States)

    National Wildlife Coordinating Group, Boise, ID.

    This document provides information and guidance on wildfire prevention strategies. Chapters include: (1) "Introduction"; (2) "How to Use this Guide"; (3) "Fire Cause Classification"; (4) "Relative Effectiveness"; (5) "Degree of Difficulty"; (6) "Intervention Techniques"; (7)…

  1. Preventing Deep Vein Thrombosis

    Science.gov (United States)

    ... you may wear special elastic stockings or inflatable boots. These devices squeeze the muscles to help keep ... Special stockings that compress the legs below the knee may help prevent blood clots from forming. However, ...

  2. Preventing High Blood Pressure

    Science.gov (United States)

    ... Heart Disease Cholesterol Salt Million Hearts® WISEWOMAN Preventing High Blood Pressure: Healthy Living Habits Recommend on Facebook Tweet Share ... meal and snack options can help you avoid high blood pressure and its complications. Be sure to eat plenty ...

  3. Disaster prevention surveillance system

    International Nuclear Information System (INIS)

    Nara, Satoru; Kamiya, Eisei

    2001-01-01

    Fuji Electric Co., Ltd. has supplied many management systems to nuclear reactor institution. 'The nuclear countermeasures-against-calamities special-measures' was enforced. A nuclear entrepreneur has devised the measure about expansion prevention and restoration of a calamity while it endeavors after prevention of generating of a nuclear calamity. Our company have supplied the 'disaster prevention surveillance system' to the Japan Atomic Energy Research Institute Tokai Research Establishment aiming at strengthening of the monitoring function at the time (after the accident) of the accident used as one of the above-mentioned measures. A 'disaster prevention surveillance system' can share the information on the accident spot in an on-site command place, an activity headquarters, and support organizations, when the serious accident happens. This system is composed of various sensors (temperature, pressure and radiation), cameras, computers and network. (author)

  4. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... Living with SCI Personal Experiences by Topic Resources Peer Counseling Blog About Media Donate Spinal Cord Injury Medical Expert Videos Topics menu Topics Preventing Pressure Sores Adult Injuries Spinal Cord Injury 101 David ...

  5. Male hypogonadism (Part 1

    Directory of Open Access Journals (Sweden)

    Ye.V. Luchytskyy

    2017-05-01

    Full Text Available The first part of the review presents the current data on the prevalence of male hypogonadism, methods of diagnosing different forms of hypogonadism, describes the clinical manifestations of the most common forms of this disease.

  6. Workshop 96. Part III

    International Nuclear Information System (INIS)

    1995-12-01

    Part III of the proceedings contain 155 contributions in various fields of science and technology including nuclear engineering, environmental science, and biomedical engineering. Out of these, 10 were selected to be inputted in INIS. (P.A.)

  7. Recognising and responding to care erosion: part 2.

    Science.gov (United States)

    de Vries, Jan Martinus Anne; Timmins, Fiona

    2017-08-23

    This article is the second in a two-part series discussing a gradual decline in standards of care, termed 'care erosion'. The first part of this article used cognitive dissonance theory to discuss the psychosocial mechanisms involved in care erosion and focused on the nurse's role in identifying and preventing declining standards in care. This article, part two, explores the wider involvement of individuals, organisations and nurse education in preventing care erosion, with a particular focus on reflection; mastery of nursing skills and care; supporting nursing values; and addressing denial and trivialisation of, and justifications for, substandard care.

  8. HPV Prevention series

    OpenAIRE

    de Sanjosé Silvia

    2012-01-01

    Abstract Human Papilloma Virus (HPV) is a major leading cause of Human Cancer. Through the HPV Prevention series we would like to highlight the quality and the breadth of the research being carried out on the Control and Prevention of HPV and HPV related disease. This series aims to bring together a diverse range of HPV related specialties featuring research that has as ultimate goal insights into HPV related disease reduction. Articles within a wide range of topics such as natural history st...

  9. Prevention of hepatocellular carcinoma.

    Science.gov (United States)

    Kew, Michael C

    2010-01-01

    Because of its frequency and grave prognosis, preventing hepatocellular carcinoma is an urgent priority. Prevention should be possible because environmental carcinogens-chronic hepatitis B and C virus infections, dietary exposure to aflatoxins, and iron overload-cause the great majority of these tumors. Chronic hepatitis B virus infection accounts for 55% of global hepatocellular carcinomas and 80% of those in the high-incidence Asia Pacific and sub-Saharan African regions. In these regions the infection that becomes chronic is predominantly acquired very early in life. A safe and effective vaccine against this virus is available and its universal inclusion in the immunization of infants has already resulted in a marked reduction of chronic infection and a 70% decrease in the occurrence of hepatocellular carcinoma in those immunized. Chronic hepatitis C virus infection is the major cause of hepatocellular carcinoma in industrialized countries. The infection is mainly acquired in adulthood and, until a vaccine becomes available, prevention will consist mainly of identifying, counselling, and treating chronically infected individuals, preventing spread of the virus by the use of safe injection practices (particularly in intravenous drug abusers), and screening all donated blood for the presence of the virus. 4.5 billion of the world.s population are exposed to dietary aflatoxins. Prevention involves treating susceptible crops to prevent fungal contamination, and handling the foodstuffs in such a way as to prevent contamination during storage. Iron overload in hereditary hemochromatosis can be prevented by repeated venesection and in African dietary iron overload by fermenting the home-brewed beer in iron-free containers.

  10. Preventive Migraine Treatment

    Science.gov (United States)

    Silberstein, Stephen D.

    2015-01-01

    Purpose of Review: This article reviews the evidence base for the preventive treatment of migraine. Recent Findings: Evidence-based guidelines for the preventive treatment of migraine have recently been published by the American Academy of Neurology (AAN) and the Canadian Headache Society (CHS), providing valuable guidance for clinicians. Strong evidence exists to support the use of metoprolol, timolol, propranolol, divalproex sodium, sodium valproate, and topiramate for migraine prevention, according to the AAN. Based on best available evidence, adverse event profile, and expert consensus, topiramate, propranolol, nadolol, metoprolol, amitriptyline, gabapentin, candesartan, Petasites (butterbur), riboflavin, coenzyme Q10, and magnesium citrate received a strong recommendation for use from the CHS. Summary: Migraine preventive drug treatments are underutilized in clinical practice. Principles of preventive treatment are important to improve compliance, minimize side effects, and improve patient outcomes. Choice of preventive treatment of migraine should be based on the presence of comorbid and coexistent illness, patient preference, reproductive potential and planning, and best available evidence. PMID:26252585

  11. Skin cancer prevention in Australia.

    Science.gov (United States)

    Sinclair, C; Foley, P

    2009-11-01

    Australia has one of the highest skin cancer incidence and mortality rates in the world. The reason for these high rates is due in part to the high ambient UV radiation levels, combined with a predominantly susceptible fair-skinned population. To address this problem, since 1980 Australians have been exposed to social marketing campaigns to raise awareness of skin cancer prevention. These campaigns have used mass media alongside interventions in schools, workplaces, and in community and leisure settings to motivate sun protective behaviour. As a result of these interventions it can be demonstrated that social marketing campaigns can be a very effective method to not only motivate behaviour change, reduce sunburn, and increase awareness but more importantly, reduce melanoma rates and bring positive economic returns to government. However long term investment in this area is required otherwise any population gains in behaviour are very likely to be quickly eroded.

  12. Overweight prevention in adolescents and children (behavioural and environmental prevention

    Directory of Open Access Journals (Sweden)

    Haas, Sabine

    2009-04-01

    Full Text Available Health political background: In 2006, the prevalence of overweight and adiposity among children and adolescents aged three to 17 years is 15%, 6.3% (800,000 of these are obese. Scientific background: Obese children and adolescents have an increased body fat ratio. The reasons for overweight are – among others – sociocultural factors, and a low social status as determined by income and educational level of the parents. The consequences of adiposity during childhood are a higher risk of metabolic and cardiovascular diseases and increased mortality in adulthood. Possible approaches to primary prevention in children and adolescents are measures taken in schools and kindergarten, as well as education and involvement of parents. Furthermore, preventive measures geared towards changing environmental and living conditions are of particular importance. Research questions: What is the effectiveness and efficiency of different measures and programs (geared towards changing behaviour and environmental and living conditions for primary prevention of adiposity in children and adolescents, with particular consideration of social aspects? Methods: The systematic literature search yielded 1,649 abstracts. Following a two-part selection process with predefined criteria 31 publications were included in the assessment. Results: The majority of interventions evaluated in primary studies take place in schools. As the measures are mostly multi-disciplinary and the interventions are often not described in detail, no criteria of success for the various interventions can be extrapolated from the reviews assessed. An economic model calculation for Australia, which compares the efficiency of different interventions (although on the basis of low evidence comes to the conclusion that the intervention with the greatest impact on society is the reduction of TV-ads geared towards children for foods and drinks rich in fat and sugar. There is a significant correlation between

  13. Global cancer patterns: causes and prevention.

    Science.gov (United States)

    Vineis, Paolo; Wild, Christopher P

    2014-02-08

    Cancer is a global and growing, but not uniform, problem. An increasing proportion of the burden is falling on low-income and middle-income countries because of not only demographic change but also a transition in risk factors, whereby the consequences of the globalisation of economies and behaviours are adding to an existing burden of cancers of infectious origin. We argue that primary prevention is a particularly effective way to fight cancer, with between a third and a half of cancers being preventable on the basis of present knowledge of risk factors. Primary prevention has several advantages: the effectiveness could have benefits for people other than those directly targeted, avoidance of exposure to carcinogenic agents is likely to prevent other non-communicable diseases, and the cause could be removed or reduced in the long term--eg, through regulatory measures against occupational or environmental exposures (ie, the preventive effort does not need to be renewed with every generation, which is especially important when resources are in short supply). Primary prevention must therefore be prioritised as an integral part of global cancer control. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. Approaches to adolescent pregnancy prevention.

    Science.gov (United States)

    Haffner, D; Casey, S

    1986-09-01

    The US has one of the highest teenage pregnancy rates in the industrialized world, over 1,000,000 a year. This can add to social problems including poverty, unemployment, family breakup, juvenile crime, school dropouts, and child abuse. In several studies various approaches have been developed and it is concluded that teens must not only be given the knowledge to avoid teen pregnancies, but the motivation to do so. Sex education is an important part of pregnancy prevention, but few programs go beyond the facts of reproduction and less than 14% of them are 40 hours long. Studies have shown mixed results as to the effect of education on teen pregnancy. There are many programs that have been developed by different communities, including computer programs and youth service agencies. Religious groups also play an important part in sex education and they have some distinct advantages in affecting teens' sexual values and activities. Education programs for teen's parents appear to be very important since studies show when sexuality is discussed at home, the teens begin activity later and use birth control more. Clinics have had difficulty recruiting and retaining teen patients and devote special attention to establishing a rapport with them. The school-based clinic is becoming increasingly popular and can provide birth control counseling, contraceptives, family planning clinic referral, examinations, pregnancy testing, and prenatal care. There success is due to confidentiality, convenience, and comprehensive service. However, since nearly all efforts on teen pregnancy prevention are directed at girls, 1/2 of those involved in teen pregnancies--males--are not participating in programs. This must change for longterm success of these programs and also the involvement of the community and media.

  15. Stroke prevention: an update.

    Science.gov (United States)

    Bousser, Marie-Germaine

    2012-03-01

    Stroke is a personal, familial, and social disaster. It is the third cause of death worldwide, the first cause of acquired disability, the second cause of dementia, and its cost is astronomic. The burden of stroke is likely to increase given the aging of the population and the growing incidence of many vascular risk factors. Prevention of stroke includes--as for all other diseases--a "mass approach" aiming at decreasing the risk at the society level and an individual approach, aiming at reducing the risk in a given subject. The mass approach is primarily based on the identification and treatment of vascular risk factors and, if possible, in the implementation of protective factors. These measures are the basis of primary prevention but most of them have now been shown to be also effective in secondary prevention. The individual approach combines a vascular risk factor modification and various treatments addressing the specific subtypes of stroke, such as antiplatelet drugs for the prevention of cerebral infarction in large and small artery diseases of the brain, carotid endarterectomy or stenting for tight carotid artery stenosis, and oral anticoagulants for the prevention of cardiac emboli. There is a growing awareness of the huge evidence-to-practice gap that exists in stroke prevention largely due to socio-economic factors. Recent approaches include low cost intervention packages to reduce blood pressure and cheap "polypills" combining in a single tablet aspirin and several drugs to lower blood pressure and cholesterol. Polypill intake should however not lead to abandon the healthy life-style measures which remain the mainstay of stroke prevention.

  16. Granulocyte-colony stimulating factor in the prevention of postoperative infectious complications and sub-optimal recovery from operation in patients with colorectal cancer and increased preoperative risk (ASA 3 and 4). Protocol of a controlled clinical trial developed by consensus of an international study group. Part three: individual patient, complication algorithm and quality manage.

    NARCIS (Netherlands)

    Stinner, B.; Bauhofer, A.; Lorenz, W.; Rothmund, M.; Plaul, U.; Torossian, A.; Celik, I.; Sitter, H.; Koller, M.; Black, A.; Duda, D.; Encke, A.; Greger, B.; Goor, H. van; Hanisch, E.; Hesterberg, R.; Klose, K.J.; Lacaine, F.; Lorijn, R.H.; Margolis, C.; Neugebauer, E.; Nystrom, P.O.; Reemst, P.H.M.; Schein, M.; Solovera, J.

    2001-01-01

    GENERAL DESIGN: Presentation of a new type of a study protocol for evaluation of the effectiveness of an immune modifier (rhG-CSF, filgrastim): prevention of postoperative infectious complications and of sub-optimal recovery from operation in patients with colorectal cancer and increased

  17. Loose part monitoring device

    International Nuclear Information System (INIS)

    Muto, Takashi.

    1990-01-01

    The object of the present invention is to eliminate unnecessary information caused by sounds which requires no analysis since the sound source is apparent. The loose parts monitoring device comprises detectors attached to an equipment constituting a flow channel, a signal controller for outputting a predetermined signal based on the signals from the detectors and a judging means for outputting an alarm upon occurrence of loose parts based on each of signal controllers. Information for a specific combination of a plurality of detectors and specific time difference are stored in the judging means. Then erroneous signals are removed by comparison between the stored information and the number of signals from a plurality of detectors within a predetermined time. Thus, in the case of predetermined combination signals, i.e., noises due to plant operation (control rod operation, etc.), for which the sound source is previously recognized, can be eliminated from loose parts signals. (T.M.)

  18. Matrix comparison, Part 2

    DEFF Research Database (Denmark)

    Schneider, Jesper Wiborg; Borlund, Pia

    2007-01-01

    The present two-part article introduces matrix comparison as a formal means for evaluation purposes in informetric studies such as cocitation analysis. In the first part, the motivation behind introducing matrix comparison to informetric studies, as well as two important issues influencing...... such comparisons, matrix generation, and the composition of proximity measures, are introduced and discussed. In this second part, the authors introduce and thoroughly demonstrate two related matrix comparison techniques the Mantel test and Procrustes analysis, respectively. These techniques can compare...... and evaluate the degree of monotonicity between different proximity measures or their ordination results. In common with these techniques is the application of permutation procedures to test hypotheses about matrix resemblances. The choice of technique is related to the validation at hand. In the case...

  19. Challenges in preventive psychiatry

    Directory of Open Access Journals (Sweden)

    Pratap Sharan

    2017-01-01

    Full Text Available Prevention of mental disorders offers opportunities for decreasing enormous health, economic, and social burden attributable to them. Substantial evidence exist showing effectiveness of prevention strategies in reducing risk factors, strengthening protective factors, and decreasing psychiatric symptoms and disability. The government and various stakeholders should work toward developing policies on national and regional levels for the prevention of mental disorders and integrate them with various public policies. Research should be focused on enhancing the evidence base for these interventions. It should also cover additional domains such as quantification of the burden of disease associated with particular risk factors, the interaction between lifestyle behaviors and mental health, and integrating mental health outcome measures in large community-based interventions for noncommunicable diseases. Special efforts should be made in devising alternative strategies to deliver these programs in low-resource settings. Integrating the research from the field of neurosciences with prevention strategies can augment the effort in this direction. One of the important challenges is to design programs that are either indigenously developed or culturally adapted. Mental health professionals have to play an important and multiple roles to make prevention of mental and behavioral disorders a reality.

  20. Diabetes mellitus prevention.

    Science.gov (United States)

    Allende-Vigo, Myriam Zaydee

    2015-01-01

    The aim of this study was to review lifestyle modification interventions and pharmacological clinical studies designed to prevent diabetes and provide evidence-based recommendations for the prevention of Diabetes Mellitus. A review of relevant literature compiled via a literature search (PUBMED) of English-language publications between 1997 and 2010 was conducted. It is found that people at increased risk of developing type 2 diabetes mellitus can halt the development of the disease. Lifestyle modification intervention with reduction of 5%-10% of excess body weight and increase in moderate physical activity by 150 min/wk has consistently proven to reduce the appearance of diabetes in different at-risk populations. Pharmacologic interventions have also demonstrated the prevention of the appearance of diabetes in persons at risk. Bariatric surgery has decreased the appearance of diabetes patients in a select group of individuals. The progression from prediabetes to diabetes mellitus can be prevented. Lifestyle modification intervention changes with weight loss and increased physical activity are currently recommended for the prevention of diabetes.

  1. 77 FR 19799 - Pipeline Safety: Pipeline Damage Prevention Programs

    Science.gov (United States)

    2012-04-02

    ... rates translate to increased public and worker safety and decreased repair and outage costs for pipeline... April 2, 2012 Part III Department of Transportation Pipeline and Hazardous Materials Safety Administration 49 CFR Parts 196 and 198 Pipeline Safety: Pipeline Damage Prevention Programs; Proposed Rule #0;#0...

  2. Multipurpose prevention technologies: products in development.

    Science.gov (United States)

    Friend, David R; Clark, Justin T; Kiser, Patrick F; Clark, Meredith R

    2013-12-01

    Multipurpose prevention technologies (MPTs) are broadly defined as products capable of simultaneously addressing multiple sexual and reproductive health needs including unintended pregnancy, STIs including HIV-1, and other reproductive tract infections. MPTs have been discussed for a few decades but little product development has occurred. With the recent proof-of-concept that a topically applied antiretroviral (ARV) can effectively reduce sexual transmission of HIV-1 (tenofovir 1% gel) the impetus to develop MPTs is gaining momentum. Products currently in development are broadly categorized as either long-acting or on-demand. Long-acting MPTs include intravaginal rings (IVRs) and long-acting injectable products. Several IVR MPTs are under development including one designed to release tenofovir to prevent transmission of HIV-1 and levonorgestrel (LNG) to prevent unintended pregnancy over a 90-day period. Another MPT IVR under development is designed to release the ARV dapivirine and LNG for 2 months. Long-acting injectable pre-exposure prophylaxis (PrEP) formulations of rilpivirine (TMC278) and GSK1265744 have entered clinical evaluation and could form the basis of long-acting injectable products for HIV-1 prevention and prevention of unintended pregnancy. On-demand products include TFV 1% gel (HIV-1/HSV-2 prevention), a zinc/carrageenan zinc gel (HIV-1/HSV-2 prevention), and the SILCS diaphragm administered with TFV 1% gel. Significant technical, funding, and regulatory hurdles must be overcome to develop most MPTs; however, the significant reproductive health benefits to many women around the world should provide motivation to overcome these hurdles. This article is based on a presentation at the "Product Development Workshop 2013: HIV and Multipurpose Prevention Technologies", held in Arlington, Virginia on February 21-22, 2013. It forms part of a special supplement to Antiviral Research. Copyright © 2013. Published by Elsevier B.V.

  3. Vitamin D and Cancer Prevention

    Science.gov (United States)

    ... Cancer Genetics Services Directory Cancer Prevention Overview Research Vitamin D and Cancer Prevention On This Page What is vitamin D? Why are cancer researchers studying a possible connection ...

  4. PHP The Good Parts

    CERN Document Server

    MacIntyre, Peter

    2010-01-01

    Get past all the hype about PHP and dig into the real power of this language. This book explores the most useful features of PHP and how they can speed up the web development process, and explains why the most commonly used PHP elements are often misused or misapplied. You'll learn which parts add strength to object-oriented programming, and how to use certain features to integrate your application with databases. Written by a longtime member of the PHP community, PHP: The Good Parts is ideal for new PHP programmers, as well as web developers switching from other languages. Become familiar w

  5. Plutonium microstructures. Part 1

    International Nuclear Information System (INIS)

    Cramer, E.M.; Bergin, J.B.

    1981-09-01

    This report is the first of three parts in which Los Alamos and Lawrence Livermore National Laboratory metallographers exhibit a consolidated set of illustrations of inclusions that are seen in plutonium metal as a consequence of inherent and tramp impurities, alloy additions, and thermal or mechanical treatments. This part includes illustrations of nonmetallic and intermetallic inclusions characteristic of major impurity elements as an aid to identifying unknowns. It also describes historical aspects of the increased purity of laboratory plutonium samples, and it gives the composition of the etchant solutions and describes the etching procedure used in the preparation of each illustrated sample. 25 figures

  6. Prevention of COPD exacerbations

    DEFF Research Database (Denmark)

    Vestbo, Jørgen; Lange, Peter

    2015-01-01

    Exacerbations have significant impact on the morbidity and mortality of patients with chronic obstructive pulmonary disease. Most guidelines emphasise prevention of exacerbations by treatment with long-acting bronchodilators and/or anti-inflammatory drugs. Whereas most of this treatment is evidence......-based, it is clear that patients differ regarding the nature of exacerbations and are likely to benefit differently from different types of treatment. In this short review, we wish to highlight this, suggest a first step in differentiating pharmacological exacerbation prevention and call for more studies...... in this area. Finally, we wish to highlight that there are perhaps easier ways of achieving similar success in exacerbation prevention using nonpharmacological tools....

  7. Prevention of food allergy

    DEFF Research Database (Denmark)

    Halken, S

    1997-01-01

    incidence of food allergy, especially cow's milk protein allergy/intolerance (CMPA/CMPI), in the first 4 years of life. As no studies have been conducted pertaining to the preventive effect of avoidance of milk and other foods after the age of 4-6 months, recommendation of preventive elimination diets......Development of a food allergy appears to depend on both genetic factors and exposure-especially in early infancy-to food proteins. In prospective studies, the effect of dietary allergy prevention programmes has only been demonstrated in high-risk infants, i.e. infants with at least one first degree...... relative with documented atopic disease. High-risk infants feeding exclusively on breast milk and/or extensively hydrolysed formula (eHF) combined with avoidance of cow's milk proteins and solid foods during at least the first 4 months of life are found to have a significant reduction in the cumulative...

  8. Prevention of acute malnutrition

    DEFF Research Database (Denmark)

    de Pee, Saskia; Grais, Rebecca; Fenn, Bridget

    2015-01-01

    Acute malnutrition is associated with increased morbidity and mortality risk. When episodes are prolonged or frequent, acute malnutrition is also associated with poor growth and development, which contributes to stunting Nutrition-specific and nutrition-sensitive strategies to prevent...... seasons or emergencies, or increased incidence of illness, such as diarrhea or measles, additional efforts are required to prevent and treat wasting. Special nutritious foods directly meet the increased nutrient requirements of children at risk for wasting; assistance to vulnerable households, in the form...... of cash or food, enables households to better meet the food, health, and other needs of household members and may increase resilience; water, sanitation, and hygiene (WASH) and health interventions help prevent and address illness and hence reduce wasting risk. The contributions of specific interventions...

  9. Prevention of food allergy

    DEFF Research Database (Denmark)

    Halken, S

    1997-01-01

    Development of a food allergy appears to depend on both genetic factors and exposure-especially in early infancy-to food proteins. In prospective studies, the effect of dietary allergy prevention programmes has only been demonstrated in high-risk infants, i.e. infants with at least one first degree...... incidence of food allergy, especially cow's milk protein allergy/intolerance (CMPA/CMPI), in the first 4 years of life. As no studies have been conducted pertaining to the preventive effect of avoidance of milk and other foods after the age of 4-6 months, recommendation of preventive elimination diets...... relative with documented atopic disease. High-risk infants feeding exclusively on breast milk and/or extensively hydrolysed formula (eHF) combined with avoidance of cow's milk proteins and solid foods during at least the first 4 months of life are found to have a significant reduction in the cumulative...

  10. Prevention of hand eczema

    DEFF Research Database (Denmark)

    Fisker, Maja H; Ebbehøj, Niels E; Vejlstrup, Søren Grove

    2018-01-01

    Objective Occupational hand eczema has adverse health and socioeconomic impacts for the afflicted individuals and society. Prevention and treatment strategies are needed. This study aimed to assess the effectiveness of an educational intervention on sickness absence, quality of life and severity...... of hand eczema. Methods PREVEX (PreVention of EXema) is an individually randomized, parallel-group superiority trial investigating the pros and cons of one-time, 2-hour, group-based education in skin-protective behavior versus treatment as usual among patients with newly notified occupational hand eczema...

  11. Preventing falls and fractures.

    Science.gov (United States)

    Ulfarsson, J; Robinson, B E

    1994-11-01

    One of four persons over age 65 in the community falls; those over age 75 in institutions fall more frequently. Falls, a complex phenomena suggesting present disease and predicting future disability, are caused by interactions between the environment and dynamic balance which is determined by the quality of sensory input, central processing, and motor responses. Clinical factors which predispose to falling often produce observable disturbances in gait and balance, making observation critical in assessment. Acute illness and drug therapy produce particularly preventable falls. Therapeutic exercise and environmental modification for safety are the clinical interventions most likely to successfully prevent fall-related injury.

  12. Preventing Errors in Laterality

    OpenAIRE

    Landau, Elliot; Hirschorn, David; Koutras, Iakovos; Malek, Alexander; Demissie, Seleshie

    2014-01-01

    An error in laterality is the reporting of a finding that is present on the right side as on the left or vice versa. While different medical and surgical specialties have implemented protocols to help prevent such errors, very few studies have been published that describe these errors in radiology reports and ways to prevent them. We devised a system that allows the radiologist to view reports in a separate window, displayed in a simple font and with all terms of laterality highlighted in sep...

  13. [Preventive strategies for dementia].

    Science.gov (United States)

    Müller, Patrick; Schmicker, Marlen; Müller, Notger G

    2017-05-01

    In the context of the demographically induced increase in the prevalence of dementia and the simultaneous lack of causal pharmacological therapies, preventive approaches are gaining in importance. By reducing risk factors and with measures which induce neuroplasticity successful aging can be supported. This article summarizes the current developments in preventing dementia by modification of life style factors. The main focus lies on the impact of cognitive and physical activity on neuroprotection. A promising approach combines both activities within a dance training program. Further studies that meet the demanding criteria of a randomized clinical trial are urgently needed.

  14. HOW TO PREVENT FRAUD?

    Directory of Open Access Journals (Sweden)

    Ionela – Corina Chersan

    2009-09-01

    Full Text Available Fraud can range from minor employee theft and unproductive behavior tomisappropriation of assets and fraudulent financial reporting. The risk of fraud can be reduced through a combination of prevention and detection measures. Moreover, prevention and deterrence measures are much less costly than the time and expense required for fraud detection and investigation. The information presented in this document generally is applicable to entities of all sizes. However, the degree to which certain programs and controls are applied in smaller, less-complex entities and the formality of theirapplication are likely to differ from larger organizations.

  15. Preventing Melanoma PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    2015-06-02

    This 60 second public service announcement is based on the June 2015 CDC Vital Signs report. Skin cancer is the most common form of cancer in the U.S. In 2011, there were more than 65,000 cases of melanoma, the most deadly form of skin cancer. Learn how everyone can help prevent skin cancer.  Created: 6/2/2015 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 6/2/2015.

  16. Building in Prevention

    DEFF Research Database (Denmark)

    Troelsen, Jens

    2013-01-01

    Health interventions can be seen as initiatives that seek to prevent the emergence and development of impaired public health. Initiatives made in the area of prophylaxis can be experienced as anything from direct invasions of personal freedom to small traffic bumps on the roads. In this spectrum...... preventive work might be changed to direct focus onto a greater extent on establishing frameworks for people to master their own lives instead of one-sided initiatives, which leave the individual with a sense of guilt at their own illness....

  17. Aspirin for Primary Prevention.

    Science.gov (United States)

    Richman, Ilana B; Owens, Douglas K

    2017-07-01

    Aspirin reduces the risk of nonfatal myocardial infarction and stroke, and the risk of colorectal cancer. Aspirin increases the risk of gastrointestinal and intracranial bleeding. The best available evidence supports initiating aspirin in select populations. In 2016, the US Preventive Services Task Force recommended initiating aspirin for the primary prevention of both cardiovascular disease and colorectal cancer among adults ages 50 to 59 who are at increased risk for cardiovascular disease. Adults 60 to 69 who are at increased cardiovascular disease risk may also benefit. There remains considerable uncertainty about whether younger and older patients may benefit. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Workshop 96. Part II

    International Nuclear Information System (INIS)

    1995-12-01

    Part II of the seminar proceedings contains contributions in various areas of science and technology, among them materials science in mechanical engineering, materials science in electrical, chemical and civil engineering, and electronics, measuring and communication engineering. In those areas, 6 contributions have been selected for INIS. (P.A.)

  19. Workshop 95. Part I

    International Nuclear Information System (INIS)

    1995-12-01

    The proceedings of the seminar contain more than 420 contributions divided into 21 areas of interest. In Part I, 144 contributions are presented from the following fields: mathematics, physics, chemistry, engineering informatics and cybernetics, computer art, and fluid mechanics. For input in INIS, 15 contributions were selected from the physics section and 1 from the chemistry section. (J.B.)

  20. MIRD methodology. Part 1

    International Nuclear Information System (INIS)

    Rojo, Ana M.

    2004-01-01

    This lecture develops the MIRD (Medical Internal Radiation Dose) methodology for the evaluation of the internal dose due to the administration of radiopharmaceuticals. In this first part, the basic concepts and the main equations are presented. The ICRP Dosimetric System is also explained. (author)

  1. Total equipment parts configuration

    International Nuclear Information System (INIS)

    Ferrare, J.

    1989-01-01

    Florida Power ampersand Lights's (FP ampersand L's) Turkey Point units were built prior to the establishment of American Society of Mechanical Engineers' Sec. III requirements. Since that time, FP ampersand L has voluntarily committed to procuring some spare and replacement parts in compliance with the ordering requirements of ASME Sec. III. New subsystems were designed according to ASME Sec. III requirements. In 1978, 10CFR21 of the Code of Federal Regulations was federally mandated. Environmental qualification concerns and the Three Mile Island incident further complicated the stocking and ordering of spare and replacement parts. Turkey Point assembled a team of quality assurance, quality control, and engineering people and obtained permission to directly access the store department computer so that catalog descriptions could be quickly made available for use by the plant. The total equipment parts configuration (TEPC) system was designed and developed under the direction of the procurement document review team at the Turkey Point nuclear plant. The system is a network of related computer data bases that identifies the equipment at the plant. The equipment (or components that make up a piece of equipment) is identified by a tag/component code system. Each component is further broken down by the manufacturer's parts list or bill of material. A description of the data available to the user, the ways these data can be accessed and displayed, and a description of the data bases and their relation to each other are summarized in this paper

  2. Workshop 93. Part A

    International Nuclear Information System (INIS)

    1993-01-01

    The aim of the seminar was to present and discuss the latest results obtained in research at the Czech Technical University and collaborating institutions. Part A of the Proceedings contains 99 contributions from the following fields: physical electronics and optics, mathematics, informatics and cybernetics, and materials engineering. Two contributions were selected for INIS. (J.B.)

  3. Meatcutting Testbook, Part I.

    Science.gov (United States)

    Strazicich, Mirko, Ed.

    This document contains objective tests for each lesson in the Meatcutting Workbook, Part I (see note), which is designed for apprenticeship programs in meatcutting in California. Each of the 36 tests contains from 10 to 45 multiple-choice items. The tests are grouped according to the eight units of the workbook: the apprentice meatcutter; applied…

  4. Basic Electricity. Part 3.

    Science.gov (United States)

    Kilmer, Donald C.

    Third (part 3) in a set of four guides designed for the student interested in a vocation in electrical work, this guide includes four units: Unit VI--Ohm's Law, covering six lessons (voltage, current-flow and resistance, the Ohm's Law formula, formula for finding voltage, formula for finding resistance); Unit VII--Voltages, covering five lessons…

  5. Machine Parts as Metaphor.

    Science.gov (United States)

    Porter, Gerald

    The connection between Language for Specific Purposes (LSP) and literature is discussed with examples of technical vocabulary drawn from a variety of writers, with particular attention to a sketch by the British dramatist Harold Pinter, "Trouble in the Works," which makes extensive use of the terminology of machine parts. It is noted…

  6. Pieces and Parts

    Science.gov (United States)

    Miller, Deborah A.; Ellis, Edith B.

    2006-01-01

    Although critical to understanding human sexuality and reproductive physiology, the male and female reproductive anatomy is often minimally covered by teachers. For teachers and students alike, it is often an embarrassing topic to discuss. This activity allows students and teachers to identify the parts of both reproductive systems with little…

  7. MIRD methodology. Part 2

    International Nuclear Information System (INIS)

    Gomez Parada, Ines

    2004-01-01

    This paper develops the MIRD (Medical Internal Radiation Dose) methodology for the evaluation of the internal dose due to the administration of radiopharmaceuticals. In this second part, different methods for the calculation of the accumulated activity are presented, together with the effective half life definition. Different forms of Retention Activity curves are also shown. (author)

  8. Violence prevention: reaching adolescents with the message.

    Science.gov (United States)

    Tucker, J B; Barone, J E; Stewart, J; Hogan, R J; Sarnelle, J A; Blackwood, M M

    1999-12-01

    To identify an effective medium for communicating with adolescents in a large-scale, cost-effective violence prevention program. A set of youth violence prevention programs was established at The Stamford Hospital, a level II trauma center. The traveling version of the program was presented to middle school students in four parts: 1) a rap music video created by our violence prevention staff, 2) a facilitated discussion about dealing with anger, 3) a video of a trauma resuscitation in our emergency department, and 4) a commercial video of a teenage boy paralyzed after a gunshot wound. A written questionnaire with a five-point rating scale (1 to 5) was used to survey the audience 1 month after the program. The survey assessed the respondents' recall of each part of the program and the perceptions of the value of each part in identifying the problem of violence and reducing violent behavior. Of 99 respondents, the highest ratings for retention, problem identification, and impact were given to the commercial video (combined average category ranking of 11.394) and the rap music video (11.182). The trauma resuscitation video and the discussion of anger were ranked as being less effective (10.253 and 9.383, respectively). The audience seemed to comprehend the main point of the program and ranked the program, as a whole, higher than any of the parts when measured by success at problem identification and impact. Effective communication with adolescents is possible through many avenues. Children of the video age respond well to visual material. A violence prevention program should incorporate effective multimedia presentations. A variety of methods in combination proves to be most effective.

  9. Prevention of non-drug addictions

    OpenAIRE

    PELECHOVÁ, Kateřina

    2010-01-01

    Non-drug addictions are part of us, including children and youth. It is important to realize that non-drug addictions influence us and are underestimated despite their seriousness. They constitute serious social-pathological phenomenon of the present. This Bachelor Thesis deals particularly with prevention and the present situation of socially undesired behaviour that is very widespread in current society. With pathological gambling, mobile phone addiction, virtual addictions, alimentary diso...

  10. Gender-Based Violence Prevention. Issues in Prevention

    Science.gov (United States)

    Higher Education Center for Alcohol, Drug Abuse, and Violence Prevention, 2012

    2012-01-01

    This issue of "Issues in Prevention" focuses on gender-based violence prevention. This issue contains the following articles: (1) Preventing Gender-Based Violence: An Overview (Linda Langford); (2) Q&A With Amelia Cobb; (3) Denim Day at HBCUs; (4) Dear Colleague Letter; (5) ED Grants for Violence Prevention; and (6) Higher Education Center…

  11. Combining biomedical preventions for HIV: Vaccines with pre-exposure prophylaxis, microbicides or other HIV preventions

    Science.gov (United States)

    McNicholl, Janet M.

    2016-01-01

    ABSTRACT Biomedical preventions for HIV, such as vaccines, microbicides or pre-exposure prophylaxis (PrEP) with antiretroviral drugs, can each only partially prevent HIV-1 infection in most human trials. Oral PrEP is now FDA approved for HIV-prevention in high risk groups, but partial adherence reduces efficacy. If combined as biomedical preventions (CBP) an HIV vaccine could provide protection when PrEP adherence is low and PrEP could prevent vaccine breakthroughs. Other types of PrEP or microbicides may also be partially protective. When licensed, first generation HIV vaccines are likely to be partially effective. Individuals at risk for HIV may receive an HIV vaccine combined with other biomedical preventions, in series or in parallel, in clinical trials or as part of standard of care, with the goal of maximally increasing HIV prevention. In human studies, it is challenging to determine which preventions are best combined, how they interact and how effective they are. Animal models can determine CBP efficacy, whether additive or synergistic, the efficacy of different products and combinations, dose, timing and mechanisms. CBP studies in macaques have shown that partially or minimally effective candidate HIV vaccines combined with partially effective oral PrEP, vaginal PrEP or microbicide generally provided greater protection than either prevention alone against SIV or SHIV challenges. Since human CBP trials will be complex, animal models can guide their design, sample size, endpoints, correlates and surrogates of protection. This review focuses on animal studies and human models of CBP and discusses implications for HIV prevention. PMID:27679928

  12. 77 FR 51612 - Petition for Exemption From the Vehicle Theft Prevention Standard; Mitsubishi Motors R&D of...

    Science.gov (United States)

    2012-08-24

    ... National Highway Traffic Safety Administration Petition for Exemption From the Vehicle Theft Prevention... the Mitsubishi vehicle line in accordance with 49 CFR part 543, Exemption from the Theft Prevention... vehicle theft as compliance with the parts-marking requirements of the Theft Prevention Standard 49 CFR...

  13. Vaccination and the prevention problem.

    Science.gov (United States)

    Dawson, Angus

    2004-11-01

    This paper seeks to critically review a traditional objection to preventive medicine (which I call here the 'prevention problem'). The prevention problem is a concern about the supposedly inequitable distribution of benefits and risks of harm resulting from preventive medicine's focus on population-based interventions. This objection is potentially applicable to preventive vaccination programmes and could be used to argue that such programmes are unethical. I explore the structure of the prevention problem by focusing upon two different types of vaccination (therapeutic vaccination and preventive vaccination). I argue that the 'prevention problem' cannot be fairly applied to the case of preventive vaccination because such programmes do not just focus upon benefits at the level of populations (as is claimed by the prevention problem). Most such preventive vaccination programmes explicitly seek to create and maintain herd protection. I argue that herd protection is an important public good which is a benefit shared by all individuals in the relevant population. This fact can then be used to block the 'prevention problem' argument in relation to preventive vaccination programmes. I conclude by suggesting that whilst the future development and use of therapeutic vaccines does raise some interesting ethical issues, any ethical objections to prophylactic vaccination on the basis of the 'prevention problem' will not be overcome through the substitution of therapeutic vaccines for preventive vaccines; indeed, the 'prevention problem' fails on its own terms in relation to preventive vaccination programmes.

  14. Theranos phenomenon - part 2.

    Science.gov (United States)

    Li, Michelle; Diamandis, Eleftherios P

    2015-11-01

    Theranos' Chief Executive Officer recently published a paper in The Wall Street Journal committing to submit all of their tests for FDA approval and renewing her promise that self-testing by the general public will empower people to detect asymptomatic disease early, which will lead to life-saving therapeutic or preventive measures. This opinion paper provides additional information on the benefits and harms of self-testing and self-interpretation of laboratory tests by asymptomatic individuals. We conclude that the health benefit claims of Theranos are hypothetical and they are not supported by evidence. Until such evidence is provided, self-testing of the healthy population should be discouraged.

  15. Drilling miniature holes, Part III

    Energy Technology Data Exchange (ETDEWEB)

    Gillespie, L.K.

    1978-07-01

    Miniature components for precision electromechanical mechanisms such as switches, timers, and actuators typically require a number of small holes. Because of the precision required, the workpiece materials, and the geometry of the parts, most of these holes must be produced by conventional drilling techniques. The use of such techniques is tedious and often requires considerable trial and error to prevent drill breakage, minimize hole mislocation and variations in hole diameter. This study of eight commercial drill designs revealed that printed circuit board drills produced better locational and size repeatability than did other drills when centerdrilling was not used. Boring holes 1 mm in dia, or less, as a general rule did not improve hole location in brass or stainless steel. Hole locations of patterns of 0.66-mm holes can be maintained within 25.4-..mu..m diametral positional tolerance if setup misalignments can be eliminated. Size tolerances of +- 3.8 ..mu..m can be maintained under some conditions when drilling flat plates. While these levels of precision are possible with existing off-the-shelf drills, they may not be practical in many cases.

  16. To Prevent Misbehavior

    OpenAIRE

    Telep, Valya Goodwin, 1955-

    2009-01-01

    This series of lessons was prepared for parents like you - parents who want to do a better job of disciplining their children. The lessons were especially written for parents of preschool children, ages two to six, but some of the discipline methods are appropriate for older children, too. This lesson focuses on preventing misbehavior.

  17. Prevention of postoperative ileus

    DEFF Research Database (Denmark)

    Holte, Kathrine; Kehlet, H

    2002-01-01

    mediators. We update evidence on the advances in the prevention and treatment on PI. As single interventions, continuous thoracic epidural analgesia with local anesthetics and minimally invasive surgery are the most efficient interventions in the reduction of PI. The effects of pharmacological agents have...

  18. Preventing School Violence

    Science.gov (United States)

    Rulloda, Rudolfo Barcena

    2011-01-01

    School violence has mushroomed into a devastating epidemic and is deteriorating the basic foundation of education. In this article, the author will present several teaching strategies for preventing school violence from becoming an arduous enigma within the classroom and school environments, and focus on assessment and reflection in order to…

  19. Preventing Adolescent Suicide.

    Science.gov (United States)

    Capuzzi, David

    The adolescent at risk for suicidal preoccupation and behavior has become an increasing concern for schools and communities. This paper presents some of the causes of teen suicide, things adults should know about adolescent suicide prevention, and what can be done to help such youth. The transition to adolescence is a complex time when many values…

  20. Preventive medicine in 2030.

    Science.gov (United States)

    Freudenberg, Nicholas

    2012-12-01

    This invited commentary imagines two futures for preventive medicine and public health in the Year 2030. Using satire, the commentary describes one future in which large corporations control public health and another where a robust public sector plays the leading role. Copyright © 2012. Published by Elsevier Inc.

  1. Eating Disorder Prevention Programming.

    Science.gov (United States)

    Sapia, Jennifer L.

    This paper provides information for school psychologists regarding the necessity and benefits of school-based prevention programming for students at risk for developing eating disorders (i.e., females). School-based programming is a cost-effective means of reaching the largest number of individuals at once and identifying those individuals…

  2. Police and Suicide Prevention.

    Science.gov (United States)

    Marzano, Lisa; Smith, Mark; Long, Matthew; Kisby, Charlotte; Hawton, Keith

    2016-05-01

    Police officers are frequently the first responders to individuals in crisis, but generally receive little training for this role. We developed and evaluated training in suicide awareness and prevention for frontline rail police in the UK. To investigate the impact of training on officers' suicide prevention attitudes, confidence, and knowledge. Fifty-three participants completed a brief questionnaire before and after undertaking training. In addition, two focus groups were conducted with 10 officers to explore in greater depth their views and experiences of the training program and the perceived impact on practice. Baseline levels of suicide prevention attitudes, confidence, and knowledge were mixed but mostly positive and improved significantly after training. Such improvements were seemingly maintained over time, but there was insufficient power to test this statistically. Feedback on the course was generally excellent, notwithstanding some criticisms and suggestions for improvement. Training in suicide prevention appears to have been well received and to have had a beneficial impact on officers' attitudes, confidence, and knowledge. Further research is needed to assess its longer-term effects on police attitudes, skills, and interactions with suicidal individuals, and to establish its relative effectiveness in the context of multilevel interventions.

  3. [Improving suicide prevention].

    Science.gov (United States)

    Debout, Michel

    2017-04-01

    Suicidal thoughts precede a suicide attempt. Knowing the people who are exposed to such thoughts enables prevention to be improved. The results of a study of the general population show that one in five French people claim to have already seriously considered committing suicide. This represents a particularly concerning public health issue. Copyright © 2017. Published by Elsevier Masson SAS.

  4. Responsible Hospitality. Prevention Updates

    Science.gov (United States)

    Colthurst, Tom

    2004-01-01

    Responsible Hospitality (RH)--also called Responsible Beverage Service (RBS)--encompasses a variety of strategies for reducing risks associated with the sale and service of alcoholic beverages. RH programs have three goals: (1) to prevent illegal alcohol service to minors; (2) to reduce the likelihood of drinkers becoming intoxicated; and (3) to…

  5. Preventable amputations in Ethiopia

    African Journals Online (AJOL)

    Sew. Mi. 6. Discussion. Gas gangre. Total. This study thus confirms that at the present time about a half of the limbs being amputated at our. Hospital (and probably throughout Ethiopia) could have been saved, or prevented by relatively simple means. These include reducing the number of road traffic accident casualties by ...

  6. Bullying Prevention for Kids

    Centers for Disease Control (CDC) Podcasts

    2012-01-19

    This podcast discusses what victims of bullying may experience and provides recommendations for coping with it.  Created: 1/19/2012 by National Center for Injury Prevention and Control (NCIPC).   Date Released: 1/19/2012.

  7. Teenage Pregnancy Prevention.

    Science.gov (United States)

    Peters, Sheila; And Others

    1991-01-01

    Peer counselors and staff members describe the "I Have a Future" Program at Meharry Medical College in Nashville (Tennessee). This program focuses on pregnancy prevention by providing education, health care, and increased life options; social skills training; an entrepreneurial program; and separate classes for African-American youth.…

  8. Wound Care: Preventing Infection

    Science.gov (United States)

    ... or wearing your Immediate Post-op or preliminary prosthesis; keep it elevated whenever possible. The limb should be raised above the level of your heart to prevent swelling. Take care of your whole self – body, mind, and spirit. Eat well and drink plenty ...

  9. Student Leadership. Prevention Updates

    Science.gov (United States)

    Langford, Linda; DeJong, William

    2010-01-01

    Campus-based efforts to reduce alcohol and other drug abuse and violence (AODV) will be more successful if they involve a wide range of stakeholders--including students--who can contribute to the program's design, implementation, and evaluation. Students provide a unique perspective on AODV prevention, and they can also bring a certain authority…

  10. Preventing Skin Cancer

    Centers for Disease Control (CDC) Podcasts

    2016-05-18

    A man and a woman talk about how they’ve learned to protect their skin from the sun over the years. .  Created: 5/18/2016 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 5/18/2016.

  11. Injury Prevention Research

    Centers for Disease Control (CDC) Podcasts

    2009-09-01

    Research provides the knowledge that we need to understand what is possible, what is not, and the best way to proceed in our intervention efforts.  Created: 9/1/2009 by National Center for Injury Prevention and Control (NCIPC).   Date Released: 9/1/2009.

  12. Prevention of relapsing backache

    Directory of Open Access Journals (Sweden)

    Raspe, Heiner

    2006-05-01

    Full Text Available Background: The condition of non-specific back pain is characterized by high prevalence, non satisfactory therapeutic options and severe socioeconomic consequences. Therefore prevention seems an attractive option to downsize the problem. However, the construction of effective preventive measures is complicated by the obscure aetiology of the condition, the multidimensionality of risk and prognostic factors (bio psychosocial model! and the variability of its natural as well as clinical course. This led to the development of a wide variety of preventive measures: e. g. exercise programs, educational measures (including back school, ergonomic modification of the work environment, mechanical supports (e. g. back belts as well as multidisciplinary interventions. For two reasons the workplace seems to be a suitable setting for prevention. First, because a number of strong risk factors are associated with working conditions and second, because it allows addressing a large proportion of the adult population. Against this background the assessment at hand sets out to answer the following questions: What is the amount and methodological quality of the available scientific literature on the effectiveness of back pain prevention in the workplace environment? What are effective measures for the prevention of back pain and its consequences in the workplace environment and how effective are they? Is back pain prevention in the workplace environment cost-effective? Is there a need for more research? As primary outcomes for effectiveness the assessment will focus on time lost from work and the frequency and duration of episodes with back pain. The preventive measures assessed belong to the following categories: exercise programs, educational and information measures, multidimensional interventions, back belts, lifting teams and ergonomic interventions. Methods: The assessment is based on a systematic review of the published literature according to the

  13. [Prevention of preeclampsia - review].

    Science.gov (United States)

    Vlk, R; Matěcha, J; Drochýtek, V

    2015-06-01

    Preeclampsia is a serious condition that affects about five percent of pregnant women. The disorder itself or related complications are responsible for a significant percentage of maternal and fetal morbidity, even in developed countries. Although our understanding of etiology is still limited, the possibility of detecting and evaluating certain angiogenic factors by the end of the first trimester gives food for thought about prospects for preeclampsia prevention. Secondary prevention is currently based mostly on the effort to pharmacologically affect the spiral artery transformation and development of the abnormal placental microcirculation which lead to clinical symptoms of preeclampsia. The preventive treatment options are narrow. Greatest effect was noted with acetylsalicylic acid medication in the at-risk population. The dose of 75-150 mg per day is considered optimal. The treatment should start before the 16th gestational week; later initiation of therapy is associated with considerably smaller effect. The incidence of the early-onset preeclampsia (preventive treatment affects the late-onset preeclampsia only minimally. Calcium supplementation is effective only in women with low calcium intake. Question for the future as well as subject of several studies is a clinical significance of low molecular weight heparin and sildenafil.

  14. Travel health prevention.

    Science.gov (United States)

    Korzeniewski, Krzysztof

    All around the world there has been a rapid growth in the number of international travels. According to the World Tourism Organisation the number of international tourist arrivals reached 1,235 billion in 2016 and continues to grow at a high rate. This has been much due to the development of air transport (including low-cost airlines), increasingly common economic migration, a growing number of travellers visiting friends and relatives, and an increase in medical tourism. With tropical destinations becoming increasingly popular among travellers, doctors have seen a rising number of patients who seek medical advice on health risks prevalent in hot countries and health prevention measures to be taken in tropical destinations, especially where sanitation is poor. The risk for developing a medical condition while staying abroad depends on a variety of factors, including the traveller's general health condition, health prevention measures taken before or during travel (vaccinations, antimalarial chemoprophylaxis, health precautions during air, road and sea travel, proper acclimatisation, prevention of heat injuries, protection against local flora and fauna, personal hygiene, water, food and feeding hygiene), as well as the prevalence of health risk factors in a given location. Health prevention is a precondition for safe travel and maintaining good physical health; in the era of a rapid growth in international tourism it has become of key importance for all travellers.

  15. Scabies: Prevention and Control

    Science.gov (United States)

    ... prevent possible reexposure and reinfestation. Bedding and clothing worn or used next to the skin anytime during the 3 days before treatment should be machine washed and dried using the hot water and hot dryer cycles or be dry-cleaned. ...

  16. Ounce of Prevention.

    Science.gov (United States)

    Cleary, Frank J.; Bell, Nathan

    1990-01-01

    Binghampton (New York) Schools begin their dropout prevention efforts even before children are born--as early as the third trimester of pregnancy. One intervention program is PACT (Parents and Children Together), which helps parents become better "first teachers." The program's success derives from parents' effectiveness as teachers and…

  17. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... OTR/L Sarah Harrison, OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, ... do to prevent pressure sores? play_arrow What role does diet and hydration play in ... play_arrow What are the six stages of a pressure sore and how ...

  18. Prevention of nuclear war

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    Removing the threat of a nuclear war-as the General Assembly formally stated in the Final Document of its first special session devoted to disarmament, in 1978-is considered to be the task of the present day. In that Document, the General Assembly sought to establish principles, guidelines and procedures for preventing nuclear war. It declared that to that end, it was imperative to remove the threat of nuclear weapons, to halt and reverse the nuclear-arms race until the total elimination of nuclear weapons and their delivery systems had been achieved (see chapter iv), and to prevent the proliferation of nuclear weapons (see chapter VII). At the same time, it called for other measures designed to prevent the outbreak of nuclear war and to lessen the danger of the treat or use of nuclear weapons. The Assembly's clear call for action was dictated by the awareness that there was no insuperable barrier dividing peace from war and that, unless nations brought the spiralling nuclear-arms race to an end, the day might come when nuclear weapons would actually be used, with catastrophic consequences. In adopting the Final Document, the international community achieved, for the first time, a consensus on an international disarmament strategy having as its immediate goal the elimination of the danger of a nuclear war and the implementation of measures to halt and reverse the arms race. The General Assembly, at its second special session on disarmament, in 1982, reaffirmed the validity of the 1978 Final Document. This paper reports that nuclear issues and in particular the prevention of nuclear war remain, however, major concerns of all States. Undoubtedly, all nations have a vital interest in the negotiation of effective measures for her prevention of nuclear war, since nuclear weapons pose a unique threat to human survival. If nuclear war were to occur, its consequences would be global, not simple regional

  19. Retinopathy of prematurity: the need for prevention

    Science.gov (United States)

    Liegl, Raffael; Hellström, Ann; Smith, Lois EH

    2016-01-01

    More than 450,000 babies are born prematurely in the USA every year. The improved survival of even the most vulnerable low body weight preterm infants has, despite improving health outcomes, led to the resurgence in preterm complications including one of the major causes for blindness in children, retinopathy of prematurity (ROP). The current mainstay in ROP therapy is laser photocoagulation and the injection of vascular endothelial growth factor (VEGF) antibodies in the late stages of the disease after the onset of neovascularization. Both are proven options for ophthalmologists to treat the severe forms of late ROP. However, laser photocoagulation destroys major parts of the retina, and the injection of VEGF antibodies, although rather simple to administer, may cause a systemic suppression of normal vascularization, which has not been studied in sufficient depth. However, the use of neither VEGF antibody nor laser treatment prevents ROP, which should be the long-term goal. It should be possible to prevent ROP by more closely mimicking the intrauterine environment after preterm birth. Such preventive measures include preventing the toxic postbirth influences (eg, oxygen excess) as well as providing the missing intrauterine factors (eg, insulin growth factor 1) and are likely to also reduce other complications of premature birth as well as ROP. This review is meant to summarize the current knowledge on the prevention of ROP with a particular emphasize on the use of insulin growth factor 1 supplementation. PMID:28539804

  20. Concern for older parts

    International Nuclear Information System (INIS)

    Titus, E.; Spink, T.; Cookson, B.; Tenera, L.P.

    1992-01-01

    For the last half decade, regulatory expectations of the procurement process for nuclear commercial-grade safety-related materials have increase. The changes have been driven by concern for fraudulent or misrepresented parts and the loss of original equipment manufacturers. The industry responded to these concerns by developing improved procurement programs that changed how parts were specified and received and provided for verification of attributes that were critical to the successful performance of safety functions(s). Like its counterparts, Duquesne Light Company (DLCo), Beaver Valley power station began applying these enhanced requirements to procurements initiated after January 1, 1990, in response to the Nuclear Management and Resources Council initiative on dedication. Procurements prior to this data were not subject to the new requirements

  1. [Prevention strategies for testicular and penile cancer: an integrative review].

    Science.gov (United States)

    de Souza, Kelly Wanessa; dos Reis, Paula Elaine Diniz; Gomes, Isabelle Pimentel; de Carvalho, Emília Campos

    2011-03-01

    Testicular and penile cancers are genital disorders that affect a small part of population, but are generally aggressive mainly because of the dramatic psychological effect they impose over patients. The purpose of this study was to identify evidence concerning preventing strategies for the referred types of cancer. An integrative literature review was performed on the COCHRANE, PubMed/MEDLINE, LILACS, BDENF and CINAHL databases using the following controlled descriptors: health promotion, risk factors, primary prevention, and urogenital neoplasms; and uncontrolled descriptors: prevention, penile cancer, testicle cancer. The studies were unanimous in concluding that self-examination of testicles is the best way to identify a possible event of testicular cancer. Circumcision, prevention for sexual transmission diseases and adequate hygiene were the most important manners for penile cancer prevention. Nurses should assume the role for general and specific health promotion, considering the major impact it would have for prevention of diseases, especially for the urogenital cancers studied in this review.

  2. Workshop 93. Part B

    International Nuclear Information System (INIS)

    1993-01-01

    The aim of the seminar was to present and discuss the latest results obtained in research at the Czech Technical University and collaborating institutions. Part B of the Proceedings contains 109 contributions from the following fields: physics; medical engineering; fluid mechanics, environmental engineering, and structural mechanics. Fourteen contributions dealing with nuclear physics, plasma physics, quantum physics, nuclear chemistry, and computational physics were selected for INIS. (J.B.)

  3. Workshop 96. Part I

    International Nuclear Information System (INIS)

    1995-12-01

    The proceedings of the seminar contain nearly 500 contributions divided into 22 fields of science and technology. In Part I, 167 contributions are presented in the following areas: mathematics, physics, chemistry, engineering informatics and cybernetics, computers, and fluid mechanics. For input in INIS, 19 contributions were selected from the Physics section, 2 from the Mathematics section, and 4 from the Chemistry section. (P.A.)

  4. Electricity Bill [Part 1

    International Nuclear Information System (INIS)

    Parkinson, C.; Hogg, N.; Salmond, A.

    1988-01-01

    The paper presents the first part of the Parliamentary debate on the second reading of the Electricity Bill, House of Commons, London 1988. The Bill sets out the government's proposals for the restructuring and privatisation of the electricity supply industry throughout Great Britain. Customers and suppliers, choice for the consumer, competition promotion, security of supply, nuclear power stations, and cost, are all discussed. (U.K.)

  5. Household Safety: Preventing Choking

    Science.gov (United States)

    ... airway) Always follow all manufacturers' age recommendations when buying toys . Some toys have small parts that can ... difficult. If you can't childproof the entire house, you can shut the doors (and install doorknob ...

  6. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... play_arrow What parts of the body are most likely to develop pressure sores? play_arrow Is ... daily skin inspections? play_arrow What are the most important things for someone with a spinal cord ...

  7. An expert system for spare parts inventory control

    International Nuclear Information System (INIS)

    Kim, K.Y.; Chen, P.Y.C.; Okrent, D.

    1987-01-01

    This paper describes an expert system which can handle spare part requirements not only in corrective maintenance (CM) or preventive maintenance (PM), but also when failure rates of components or parts are updated by new data or by predictive maintenance (PDM), and which can also decide optimum stocking level of each spare part. This expert system provides a maintenance (or inventory) manager with an improved basis for decision making in the maintenance related to spare parts. The definitions of PM and PDM from NUREG-1212 (USNRC 1986) are used herein. This expert system used Intellignece/Compiler (Intelligence Ware, 1986) as a language/tool in the IBM-PC

  8. 24 CFR 200.37 - Preventing crime in federally assisted housing.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Preventing crime in federally... Regulations § 200.37 Preventing crime in federally assisted housing. See part 5, subparts I and J of this title, for provisions concerning preventing crime in federally assisted housing, including programs...

  9. Breaking the rhythm of depression : Cognitive Behavior Therapy and relapse prevention for depression

    NARCIS (Netherlands)

    Bockting, Claudi L.H.

    2010-01-01

    A crucial part of the treatment of depression is the prevention of relapse and recurrence. Psychological interventions, especially cognitive behavior therapy (CBT) are helpful in preventing relapse and recurrence in depression. The effectivity of four types of relapse prevention cognitive behavior

  10. 77 FR 15843 - Petition for Exemption From the Vehicle Theft Prevention Standard; Nissan

    Science.gov (United States)

    2012-03-16

    ... From the Vehicle Theft Prevention Standard; Nissan AGENCY: National Highway Traffic Safety... document grants in full Nissan North America, Inc.'s (Nissan) petition for exemption of the Juke vehicle... compliance with the parts-marking requirements of the Theft Prevention Standard (49 CFR part 541). Nissan...

  11. 77 FR 29752 - Petition for Exemption From the Federal Motor Vehicle Motor Theft Prevention Standard; Jaguar...

    Science.gov (United States)

    2012-05-18

    ... Petition for Exemption From the Federal Motor Vehicle Motor Theft Prevention Standard; Jaguar Land Rover... is likely to be as effective in reducing and deterring motor vehicle theft as compliance with the parts-marking requirements of the Federal Motor Vehicle Theft Prevention Standard, 49 CFR part 541...

  12. 75 FR 6254 - Petition for Exemption From the Vehicle Theft Prevention Standard; Mazda

    Science.gov (United States)

    2010-02-08

    ... National Highway Traffic Safety Administration Petition for Exemption From the Vehicle Theft Prevention... in reducing and deterring motor vehicle theft as compliance with the parts-marking requirements of... to 49 CFR part 543, Exemption from Vehicle Theft Prevention Standard, based on the installation of an...

  13. 77 FR 20486 - Petition for Exemption From the Vehicle Theft Prevention Standard; Mitsubishi Motors

    Science.gov (United States)

    2012-04-04

    ... National Highway Traffic Safety Administration Petition for Exemption From the Vehicle Theft Prevention... equipment is likely to be as effective in reducing and deterring motor vehicle theft as compliance with the parts-marking requirements of the 49 CFR part 541, Federal Motor Vehicle Theft Prevention Standard...

  14. 78 FR 24304 - Petition for Exemption From the Vehicle Theft Prevention Standard; Maserati North America Inc.

    Science.gov (United States)

    2013-04-24

    ... National Highway Traffic Safety Administration Petition for Exemption From the Vehicle Theft Prevention... equipment is likely to be as effective in reducing and deterring motor vehicle theft as compliance with the... parts-marking pursuant to 49 CFR Part 543, Exemption from Vehicle Theft Prevention Standard, based on...

  15. Overturn of the proposed alcohol advertising ban in Lithuania.

    Science.gov (United States)

    Paukštė, Ernesta; Liutkutė, Vaida; Stelemėkas, Mindaugas; Goštautaitė Midttun, Nijolė; Veryga, Aurelijus

    2014-05-01

    In response to the dramatic increase in alcohol-related problems in Lithuania, policy measures, including alcohol advertising and availability restrictions combined with taxation increase, were implemented in 2007-08. Simultaneously, a full alcohol advertising ban was adopted to take effect from 1 January 2012. Therefore, the alcohol industry responded with extensive lobbying aiming to revoke this ban, and ultimately they succeeded at the end of December 2011. To document and analyse actions of stakeholders and events during the alcohol advertising ban cancellation process in Lithuania. Policy analysis includes a development of event time-line, description of key stakeholders' actions and a review of policy context. The alcohol industry in Lithuania used similar tactics as the tobacco industry globally, such as creating strong and diverse opposing groups. The industry successfully exerted pressure to change alcohol control legislation, while non-governmental organizations had the important role of a watchdog, blunting industry's efforts. Unequal power distribution made it difficult to withstand combined local and international lobbying to cancel the ban. Given the global nature of the alcohol industry, there is a need for international regulation to limit the influence of vested interests on national lawmaking. © 2014 Society for the Study of Addiction.

  16. Impact of interbasin exchange on the Atlantic overturning circulation

    NARCIS (Netherlands)

    Weijer, W.; Ruijter, W.P.M. de; Dijkstra, H.A.; Leeuwen, P.J. van

    2000-01-01

    The thermohaline exchange between the Atlantic and the Southern Ocean is analyzed, using a data set based on WOCE hydrographic data. It is shown that the salt and heat transports brought about by the South Atlantic subtropical gyre play an essential role in the Atlantic heat and salt budgets. It

  17. Court overturns ruling on housing of homeless with HIV.

    Science.gov (United States)

    1996-09-06

    The New York Court of Appeals struck down a lower court finding that New York City's shelter program for the homeless with HIV failed to promise minimum protection against tuberculosis (TB). A class action led by [name removed] claimed that people who do not fit the Federal definition of AIDS are placed in a segregated, dormitory-like area of city shelters. They share common eating and bathroom facilities. The Supreme Court's Appellate Division concluded that this arrangement was improper because it failed to protect people with HIV against the danger of contracting TB. The Court of Appeals unanimously reversed the decision.

  18. Targeting burn prevention in Ukraine: evaluation of base knowledge in burn prevention and first aid treatment.

    Science.gov (United States)

    Gamelli, Liza; Mykychack, Iryna; Kushnir, Antin; Driscoll, Daniel N; Fuzaylov, Gennadiy

    2015-01-01

    Burn prevention has been identified by the World Health Organization (WHO) as a topic in need of further investigation and education throughout the world, with an increased need in low-income countries. It has been noted that implementing educational programs for prevention in high income countries has aided in lowering the rate of burn injuries. The purpose of this study is to evaluate the current education level of knowledge of prevention and first aid treatment of scald burns. A prevention campaign will target these educational needs as a part of an outreach program to improve burn care in Ukraine. The research team evaluated the current health structure in Ukraine and how it could benefit from the increased knowledge of burn prevention and first aid. A test was designed to assess the baseline level of knowledge with regard to first aid and scald prevention in parents, pregnant woman, and healthcare and daycare providers. A total of 14,456 tests were sent to pediatric clinics, obstetrician clinics, and daycare facilities to test respondents. A total of 6,120 completed tests were returned. Doctors presented with the highest level of knowledge averaging 77.0% on prevention and 67.5% on first aid while daycare workers presented the largest gap in knowledge at 65.0% in prevention and 54.3% in first aid. Interest in further educational materials was reported by 92% of respondents. The results of this study clearly show a lack of knowledge in first aid and prevention of scald burn injury in all the populations tested.

  19. Let's prevent diabetes

    DEFF Research Database (Denmark)

    Gray, Laura J.; Khunti, Kamlesh; Williams, Sian

    2012-01-01

    Background: The prevention of type 2 diabetes is a globally recognised health care priority, but there is a lack of rigorous research investigating optimal methods of translating diabetes prevention programmes, based on the promotion of a healthy lifestyle, into routine primary care. The aim...... of the study is to establish whether a pragmatic structured education programme targeting lifestyle and behaviour change in conjunction with motivational maintenance via the telephone can reduce the incidence of type 2 diabetes in people with impaired glucose regulation (a composite of impaired glucose...... of type 2 diabetes. Secondary outcomes include changes in HbA1c, blood glucose levels, cardiovascular risk, the presence of the Metabolic Syndrome and the cost-effectiveness of the intervention.Methods: The study consists of screening and intervention phases within 44 general practices coordinated from...

  20. [Anxiety prevention among schoolchildren].

    Science.gov (United States)

    Essau, C A; Conradt, J; Ederer, E M

    2004-09-01

    The FRIENDS programme is a prevention and early intervention programme, which teaches children strategies to cope with anxiety and challenging situations. This paper examines the social validity of the German version of the FRIENDS programme using data from a large-scale study on the prevention of anxiety disorders in schoolchildren, which is funded by the Dr. Karl-Wilder Stiftung. In this paper, data of 208 schoolchildren (aged 9 to 12 years) are used. Results show that the children and their parents were highly satisfied with the FRIENDS programme. Childrens attendance and completion of their homework assignments were very high. Both the children and their parents rated relaxation exercises and thinking helpful thoughts as being more useful for the children than other skills. Treatment acceptability correlated significantly with the childrens clinical outcome. The implications of our findings for future research are discussed.

  1. Preventive Radiation Protection Act

    International Nuclear Information System (INIS)

    Roewer, H.

    1988-01-01

    The commentary is intended to contribute to protection of the population by a practice-oriented discussion and explanation of questions arising in connection with the Preventive Radiation Protection Act. Leaving aside discussions about abandonment of nuclear power, or criticism from any legal point of view, the commentary adopts the practical approach that accepts, and tries to help implementing, the act as it is. It is a guide for readers who are not experts in the law and gives a line of orientation by means of explanations and sometimes by citations from other acts (in footnotes). The commentary also presents the EURATOM Directive No. 3954/87 dated 22 December 1987, the EC Directive No. 3955/87 dated 22 December 1987, and the EC Directive No. 1983/88 dated 5 July 1988. A tabular survey shows the system of duties and competences defined by the Preventive Radiation Protection Act. (RST) [de

  2. [Prevention of diabetic foot].

    Science.gov (United States)

    Metelko, Zeljko; Brkljacić Crkvencić, Neva

    2013-10-01

    Diabetic foot (DF) is the most common chronic complication, which depends mostly on the duration and successful treatment of diabetes mellitus. Based on epidemiological studies, it is estimated that 25% of persons with diabetes mellitus (PwDM) will develop the problems with DF during lifetime, while 5% do 15% will be treated for foot or leg amputation. The treatment is prolonged and expensive, while the results are uncertain. The changes in DF are influenced by different factors usually connected with the duration and regulation of diabetes mellitus. The first problems with DF are the result of misbalance between nutritional, defensive and reparatory mechanisms on the one hand and the intensity of damaging factors against DF on the other hand. Diabetes mellitus is a state of chronic hyperglycemia, consisting of changes in carbohydrate, protein and fat metabolism. As a consequence of the long duration of diabetes mellitus, late complications can develop. Foot is in its structure very complex, combined with many large and small bones connected with ligaments, directed by many small and large muscles, interconnected with many small and large blood vessels and nerves. Every of these structures can be changed by nutritional, defensive and reparatory mechanisms with consequential DE Primary prevention of DF includes all measures involved in appropriate maintenance of nutrition, defense and reparatory mechanisms.First, it is necessary to identify the high-risk population for DF, in particular for macrovascular, microvascular and neural complications. The high-risk population of PwDM should be identified during regular examination and appropriate education should be performed. In this group, it is necessary to include more frequent and intensified empowerment for lifestyle changes, appropriate diet, regular exercise (including frequent breaks for short exercise during sedentary work), regular self control of body weight, quit smoking, and appropriate treatment of glycemia

  3. Prevention of preeclampsia.

    Science.gov (United States)

    Grotegut, Chad A

    2016-12-01

    Preeclampsia is a common complication of pregnancy that is associated with an increased risk of maternal and neonatal morbidity and mortality. Currently, delivery is the only cure for preeclampsia; therefore, effective prevention and treatment options for this condition are sorely needed. In the current issue of the JCI, Mirzakhani et al. report the findings of the Vitamin D Antenatal Asthma Reduction Trial (VDAART), a well-conducted large, randomized, double-blind, placebo-controlled trial of vitamin D supplementation for the prevention of preeclampsia. Though vitamin D supplementation had no effect on the risk of preeclampsia, reduced maternal serum vitamin D levels did correlate with preeclampsia risk. Mirzakhani and colleagues identified a number of gene pathways that are differentially regulated among women with low serum vitamin D levels who develop preeclampsia. These results indicate that further research on the role of vitamin D in preeclampsia is warranted.

  4. The Prevention of Thalassemia

    Science.gov (United States)

    Cao, Antonio; Kan, Yuet Wai

    2013-01-01

    The thalassemias are among the most common inherited diseases worldwide, affecting individuals originating from the Mediterranean area, Middle East, Transcaucasia, Central Asia, Indian subcontinent, and Southeast Asia. As the diseases require long-term care, prevention of the homozygous state constitutes a major armament in the management. This article discusses the major prevention programs that are set up in many countries in Europe, Asia, and Australia, often drawing from the experience in Sardinia. These comprehensive programs involve carrier detections, molecular diagnostics, genetic counseling, and prenatal diagnosis. Variability of clinical severity can be attributable to interactions with α-thalassemia and mutations that increase fetal productions. Special methods taht are currently quite expensive and not widely applicable are preimplantation and preconception diagnosis. The recent successful studies of fetal DNA in maternal plasma may allow future prenatal diagnosis that is noninvasive for the fetus. PMID:23378598

  5. Cancer prevention by phytochemicals.

    Science.gov (United States)

    Nishino, Hoyoku; Murakoshi, Michiaki; Mou, Xiao Yang; Wada, Saeri; Masuda, Mitsuharu; Ohsaka, Yasuhito; Satomi, Yoshiko; Jinno, Kenji

    2005-01-01

    Information has been accumulated indicating that diets rich in vegetables and fruits can reduce the risk of a number of chronic diseases, including cancer, cardiovascular disease, diabetes and age-related macular degeneration. Phytochemicals (various factors in plant foods), such as carotenoids, antioxidative vitamins, phenolic compounds, terpenoids, steroids, indoles and fibers, have been considered responsible for the risk reduction. Among them, a mixture of natural carotenoids has been studied extensively and proven to show beneficial effects on human cancer prevention.

  6. Culturally Relevant Cyberbullying Prevention

    OpenAIRE

    Phillips, Gregory John

    2017-01-01

    In this action research study, I, along with a student intervention committee of 14 members, developed a cyberbullying intervention for a large urban high school on the west coast. This high school contained a predominantly African American student population. I aimed to discover culturally relevant cyberbullying prevention strategies for African American students. The intervention committee selected video safety messages featuring African American actors as the most culturally relevant cyber...

  7. Prevention of criticality accidents

    International Nuclear Information System (INIS)

    Canavese, S.I.

    1982-01-01

    These notes used in the postgraduate course on Radiological Protection and Nuclear Safety discuss macro-and microscopic nuclear constants for fissile materials systems. Critical systems: their definition; criteria to analyze the critical state; determination of the critical size; analysis of practical problems about prevention of criticality. Safety of isolated units and of sets of units. Application of standards. Conception of facilities from the criticality control view point. (author) [es

  8. The prevention of dementia.

    Science.gov (United States)

    Peters, Ruth

    2009-05-01

    Dementia is prevalent in older adults and the population is ageing. Many factors have been associated with dementia and anything that may aid the prevention of dementia is of importance. The literature in this area was evaluated and information relating to the various factors that may impact upon the prevention of dementia is presented below. Factors that have been associated with a possible increased risk of developing dementia include high blood pressure, (at least in midlife), high body mass index, smoking and possibly diabetes although the evidence is mixed. There is currently no clear evidence with regard to cholesterol and metabolic syndrome although both may be implicated. Having education and maintaining a Mediterranean diet, including vegetable, fruit and fish intake, have been linked to a lower incidence of dementia as has low to moderate alcohol intake. Although care must be taken with the latter given the different characteristics of the studies reporting on alcohol and dementia. It may be that risk and protective factors vary with age, however, in the absence of prophylactic treatment it seems likely that the maintenance of a healthy lifestyle may represent the best option with regard to the prevention of dementia. (c) 2008 John Wiley & Sons, Ltd.

  9. Java The Good Parts

    CERN Document Server

    Waldo, Jim

    2010-01-01

    What if you could condense Java down to its very best features and build better applications with that simpler version? In this book, veteran Sun Labs engineer Jim Waldo reveals which parts of Java are most useful, and why those features make Java among the best programming languages available. Every language eventually builds up crud, Java included. The core language has become increasingly large and complex, and the libraries associated with it have grown even more. Learn how to take advantage of Java's best features by working with an example application throughout the book. You may not l

  10. R806 (part 1)

    CERN Multimedia

    CERN PhotoLab

    1976-01-01

    R806 was designed by the BNL-CERN-Syracuse-Yale Collaboration (Bill Willis spokesman) to study large transverse momentum phenomena, and installed in intersection 8 of the ISR. The main detectors were Lithium foil transition radiation detectors to identify electrons and liquid argon calorimeters to measure the energy of the electrons and photons (among the first such calorimeters to be used in an experiment). In part 1 there were two modules, top and bottom of the horizontal beam pipe; the black vertical pipe contains the cryogenics (LN2 and Lar) and is connected to the two modules with the horizontal piping.

  11. Endocrine system: part 1.

    Science.gov (United States)

    Johnstone, Carolyn; Hendry, Charles; Farley, Alistair; McLafferty, Ella

    2014-05-27

    This article, which forms part of the life sciences series and is the first of two articles on the endocrine system, examines the structure and function of the organs of the endocrine system. It is important that nurses understand how the endocrine system works and its role in maintaining health. The role of the endocrine system and the types, actions and control of hormones are explored. The gross structure of the pituitary and thyroid glands are described along with relevant physiology. Several disorders of the thyroid gland are outlined. The second article examines growth hormone, the pancreas and adrenal glands.

  12. Guidelines for prevention in psychology.

    Science.gov (United States)

    2014-04-01

    The effectiveness of prevention to enhance human functioning and reduce psychological distress has been demonstrated. From infancy through adulthood, access to preventive services and interventions is important to improve the quality of life and human functioning and reduce illness and premature death. The importance of prevention is consistent with the Patient Protection and Affordable Care Act of 2010. Even with the increased focus on prevention, psychology training programs rarely require specific courses on prevention. In particular, conceptualizations about best practices in prevention, particularly at the environmental level, are lacking. Therefore, psychologists engaged in prevention can benefit from a set of guidelines that address and inform prevention practices. Accordingly, the Guidelines for Prevention in Psychology are intended to "inform psychologists, the public, and other interested parties regarding desirable professional practices" in prevention. The Prevention Guidelines are recommended based on their potential benefits to the public and the professional practice of psychology. They support prevention as an important area of practice, research, and training for psychologists. The Guidelines give increased attention to prevention within APA, encouraging psychologists to become involved with preventive activities relevant to their area of practice. (PsycINFO Database Record (c) 2014 APA, all rights reserved).

  13. Development of Preventive Measures to Prevent School Absenteeism in Twente

    NARCIS (Netherlands)

    Van Liere, Annette; Ritzen, Henk; Brand-Gruwel, Saskia

    2011-01-01

    Van Liere, A., Ritzen, H., & Brand-Gruwel, S. (2011, August). Development of Preventive Measures to Prevent School Absenteeism in Twente. Paper presented at 14th Biennial Conference for Research on Learning and Instruction of EARLI, Exeter, England.

  14. Prevention literacy: community-based advocacy for access and ownership of the HIV prevention toolkit.

    Science.gov (United States)

    Parker, Richard G; Perez-Brumer, Amaya; Garcia, Jonathan; Gavigan, Kelly; Ramirez, Ana; Milnor, Jack; Terto, Veriano

    2016-01-01

    efforts are limited and unsustainable. Success of prevention efforts depends on equity of access, community-based ownership, and multilevel support structures to enable usage and sustainability. For existing HIV prevention efforts to be effective in "real-world" settings, with limited resources, reflection on historical lessons and contextual realities (i.e. policies, financial constraints, and biomedical patents) indicated the need to extend principles developed for treatment access and treatment literacy, to support prevention literacy and prevention access as an integral part of the global response to HIV.

  15. Community Colleges--Prevention Challenges. Issues in Prevention

    Science.gov (United States)

    Higher Education Center for Alcohol, Drug Abuse, and Violence Prevention, 2012

    2012-01-01

    This issue of "Issues in Prevention" focuses on prevention challenges facing community colleges. This issue contains the following articles: (1) Prevention at Community Colleges; (2) Q&A With William Auvenshine; (3) Chancellor's Initiative at the University of Wisconsin-Stout; (4) Alcohol Marketing in the Digital Age; and (5) Higher Education…

  16. Role of Enforcement in Prevention. Issues in Prevention

    Science.gov (United States)

    Higher Education Center for Alcohol, Drug Abuse, and Violence Prevention, 2012

    2012-01-01

    This issue of "Issues in Prevention" focuses on the role of enforcement in prevention. This issue contains the following articles: (1) What the Evidence Tells Us about the Role of Enforcement in Prevention; (2) Campus Briefs; (3) Q&A with Charles Cychosz; and (4) Higher Education Center Resources.

  17. Primary teachers about the connection between social games and preventive discipline

    OpenAIRE

    Pravne, Romana

    2011-01-01

    The main theme of the degree paper is preventive discipline, which is essential for the pedagogic work of a teacher. Especially set out is the question of the connection between single aspects of preventive discipline and social games. The idea of the connection between these fields is derived from the preventive concept Oratorij, where Giovanni don Bosco stressed games as the key part of preventive work. Recently professional writings have been frequently setting out social games as importan...

  18. LGBTQ Part 2.

    Science.gov (United States)

    Perron, Tracy; Kartoz, Connie; Himelfarb, Chaya

    2017-03-01

    In addition to dealing with the normal challenges of being a teenager, many times LGBTQ youth have to deal with harassment, intimidation, and bullying on a daily basis as they disproportionately experience verbal and physical harassment while in school as a result of their sexual orientation and/or gender identity. This violence adversely affects these students' health and well-being as reflected in the depression and suicide rate among LGBTQ youth. As Part 2 of a series in articles on caring for LGBTQ youth in a school setting, this article reviews specific health risks in this group of students. School nurses can help reduce disparities in health for LGBTQ youth by understanding risk for psychological consequences of bullying and advocating for a just and responsive social school culture. Implications for school nurses include educating school staff and families as well as providing prompt and appropriate referrals for necessary psychological care.

  19. Son: Part One

    Directory of Open Access Journals (Sweden)

    Jennifer Higgie

    2004-08-01

    Full Text Available It is 1842. Two Englishman set out on a Grand Tour of Europe and the Middle East. One is a young, gifted artist; the other a Gentleman. By the time they return to England, the artist has become a devotee of the Egyptian god Osiris. One night, after dining together in a small inn in Cobham, he violently murders his beloved father, believing him to be an imposter. Why? Son is a novel inspired by the life of Richard Dadd, one of the greatest Victorian painters and inmate of Bethlem Hospital - more commonly known as Bedlam. Part Two of Son will be published in Portal vol. 2, no. 1, January 2005.

  20. Part 6: Forest monitoring

    International Nuclear Information System (INIS)

    1997-01-01

    In this part the results of forest monitoring on Hungarian and Slovak territory are presented. The two countries examine the growth and the health conditions of trees in similar ways. The monitoring sites in the Slovak and Hungarian territories, included in the joint monitoring, are shown on figure. The Slovak Party has already evaluated the wood yield data for 1996, the weekly girth growth observations in 1996 were not performed yet. So far on the Hungarian side only the weekly girth growth data are available for the year 1996, the wood yield data for 1996 are being processed. In the evaluation of Hungarian side only the results obtained for the period from 1992 to 1995 were analysed. Moreover, on the Slovak side an evaluation of the health conditions of trees based on aerial was carried out. The Hungarian party did not carried out such a survey, therefore the evaluation is based only on field (on-the-spot) observations