Sample records for prevalence phenomenology aetiology

  1. Prevalence, Phenomenology, Aetiology and Predictors of Challenging Behaviour in Smith-Magenis Syndrome (United States)

    Sloneem, J.; Oliver, C.; Udwin, O.; Woodcock, K. A.


    Background: The prevalence, phenomenology aetiology and correlates of four forms of challenging behaviour in 32 children and adults with Smith-Magenis syndrome (SMS) were investigated. Methods: Cognitive assessments, questionnaires and semi-structured interviews were used to gather data on intellectual disability, verbal and physical aggression,…

  2. Prevalence, aetiology and antibiotic sensitivity profile of ...

    African Journals Online (AJOL)

    Escherichia coli were the common organism isolated at 38.8%. The majority of the organisms were sensitive to imipenem and gentamycin. Conclusion: There is a high prevalence of ASB among pregnant women included in the study from the Nairobi county clinics. Therefore, routine ASB screening of pregnant women is ...

  3. Seasonal trends in the prevalence of hypospadias: Aetiological implications. (United States)

    Mamoulakis, C; Avgenakis, G; Gkatzoudi, C; Duyker, G; Zisis, I E; Heretis, I; Antypas, S; Sofikitis, N; Spandidos, D A; Tsatsakis, A M; Tzonou, A


    The aim of the present study was to examine the seasonality of hypospadias in Greece in an attempt to elucidate the aetiology. All boys born between 1991-1998, who underwent hypospadias repair at 'Aghia Sophia' Children's Hospital, Athens (n=542) were analysed. All Greek live-born males during the same period (population at risk; m=421,175) served as the controls. Seasonality by month of birth was evaluated with specific statistical tools. Meteorological parameters were also analysed. All tests yielded significant results, suggesting a simple harmonic prevalence pattern (highest/lowest: autumn, peak in October/spring, trough in April). Therefore, the first trimester of hypospadiac gestations coincides more frequently with winter. Meteorological parameters varied seasonally (maximal sunlight; air temperature in summer/minimal in winter, maximal rainfall in winter/minimal in summer) and were strongly associated pairwise. Hypospadiac birth prevalence follows a simple harmonic seasonal pattern and is associated with that of cryptorchidism in Greece. The coincidence of the first or third trimester of a potentially genetically influenced gestation with winter could lead to the phenotypic expression of hypospadias or cryptorchidism, respectively. The potential role of a cyclic-varied androgen-production stimulator, such as human chorionic gonadotrophin may be speculated. The seasonality of a common environmental factor acting directly/indirectly may contribute to these patterns, and possibly to the common pathogenesis of these congenital malformations.

  4. Prevalence of potential underlying aetiology of macrocytic anaemia in Dutch general practice

    NARCIS (Netherlands)

    K. Stouten (Karlijn); J.A. Riedl (Jurgen); J. Droogendijk (Jolanda); Castel, R. (Rob); J.M. van Rosmalen (Joost); R.J. Van Houten; P.B. Berendes (Paul); P. Sonneveld (Pieter); M.-D. Levin (Mark-David)


    textabstractBackground: Macrocytic anaemia (MCV ≥ 100 fL) is a relatively common finding in general practice. However, literature on the prevalence of the different causes in this population is limited. The prevalence of macrocytic anaemia and its underlying aetiology were analysed in a general

  5. Prevalence and aetiology of subclinical mastitis in goats

    Directory of Open Access Journals (Sweden)

    Igor Štoković


    Full Text Available The study was conducted in 2006 on 20 French alpine goat farms in Croatia. Milk samples were taken from each udder half, for the mastitis test and the bacteriological test, 2120 samples in total. Subclinical mastitis was diagnosed in 211 out of 1060 goats, or in 20% of the studied population. Mastitis of one udder half was diagnosed in 84% of the affected population, while mastitis of both udder halves was diagnosed in 16% of the affected goats. A positive mastitis test reaction was identified in 605 samples (28%, and the pathogenic bacterium was isolated from 244 of these samples (36%. From 22 samples (1.5% which were negative to mastitis test, pathogenic bacteria, namely S. aureus (21 samples and Streptococcus D (1 sample, were isolated. Staphylococcus aureus was isolated from 72% mastitis test positive samples, coagulase-negative staphylococci in 16%, other bacteria were isolated from a smaller number of samples: Streptococcus D (6%, Bacillus spp. (2%, and E. coli (2%. The results of the study lead to the conclusion that the subclinical mastitis in goats has a prevalence of 20% on average which increases with higher lactation number. Staphylococcus aureus is the primary causative agent of the inflammations.

  6. Parkinson’s Disease – the Debate on the Clinical Phenomenology, Aetiology, Pathology and Pathogenesis (United States)

    Jenner, Peter; Morris, Huw R.; Robbins, Trevor W.; Goedert, Michel; Hardy, John; Ben-Shlomo, Yoav; Bolam, Paul; Burn, David; Hindle, John V.; Brooks, David


    The definition of Parkinson’s disease (PD) is changing with the expansion of clinical phenomenology and improved understanding of environmental and genetic influences that impact on the pathogenesis of the disease at the cellular and molecular level. This had led to debate and discussion with as yet, no general acceptance of the direction that change should take either at the level of diagnosis or of what should and should not be sheltered under an umbrella of PD. This article is one contribution to this on-going discussion. There are two different themes running through the article - widening the definition of PD/LBD/synucleinopathies and the heterogeneity that exists within PD itself from a clinical, pathological and genetic per-spective. The conclusion reached is that in the future, further diagnostic categories will need to be recognized. These are likely to include - Parkinson’s syndrome, Parkinson’s syndrome likely to be Lewy body PD, clinical PD (defined by QSBB criteria), Lewy body disease (PD, LBD, REM SBD) and synucleinopathies (including LBD, MSA). PMID:23938306

  7. Parkinson's disease--the debate on the clinical phenomenology, aetiology, pathology and pathogenesis. (United States)

    Jenner, Peter; Morris, Huw R; Robbins, Trevor W; Goedert, Michel; Hardy, John; Ben-Shlomo, Yoav; Bolam, Paul; Burn, David; Hindle, John V; Brooks, David


    The definition of Parkinson's disease (PD) is changing with the expansion of clinical phenomenology and improved understanding of environmental and genetic influences that impact on the pathogenesis of the disease at the cellular and molecular level. This had led to debate and discussion with as yet, no general acceptance of the direction that change should take either at the level of diagnosis or of what should and should not be sheltered under an umbrella of PD. This article is one contribution to this on-going discussion. There are two different themes running through the article--widening the definition of PD/LBD/synucleinopathies and the heterogeneity that exists within PD itself from a clinical, pathological and genetic perspective. The conclusion reached is that in the future, further diagnostic categories will need to be recognized. These are likely to include--Parkinson's syndrome, Parkinson's syndrome likely to be Lewy body PD, clinical PD (defined by QSBB criteria), Lewy body disease (PD, LBD, REM SBD) and synucleinopathies (including LBD, MSA).

  8. Retrospective study of concussive convulsions in elite Australian rules and rugby league footballers: phenomenology, aetiology, and outcome. (United States)

    McCrory, P R; Bladin, P F; Berkovic, S F


    To study the ictal phenomenology, aetiology, and outcome of convulsions occurring within seconds of impact in violent collision sport. Retrospective identification of convulsions associated with concussive brain injury from case records from medical officers of football clubs over a 15 year period. Elite Australian rules and rugby league footballers. Neuroimaging studies, electroencephalography, neuropsychological test data, and statistics on performance in matches to determine presence of structural or functional brain injury. Clinical follow up and electroencephalography for evidence of epilepsy. Twenty two cases of concussive convulsions were identified with four events documented on television videotape. Convulsions began within 2 seconds of impact and comprised an initial period of tonic stiffening followed by myoclonic jerks of all limbs lasting up to 150 seconds. Some asymmetry in the convulsive manifestations was common, and recovery of consciousness was rapid. No structural or permanent brain injury was present on clinical assessment, neuropsychological testing, or neuroimaging studies. All players returned to elite competition within two weeks of the incident. Epilepsy did not develop in any player over a mean (range) follow up of 3.5 (1-13) years. These concussive or impact convulsions are probably a non-epileptic phenomenon, somewhat akin to convulsive syncope. The mechanism may be a transient traumatic functional decerebration. In concussive convulsions the outcome is universally good, antiepileptic treatment is not indicated, and prolonged absence from sport is unwarranted.

  9. The Prevalence and Phenomenology of Repetitive Behavior in Genetic Syndromes (United States)

    Moss, Joanna; Oliver, Chris; Arron, Kate; Burbidge, Cheryl; Berg, Katy


    We investigated the prevalence and phenomenology of repetitive behavior in genetic syndromes to detail profiles of behavior. The Repetitive Behaviour Questionnaire (RBQ) provides fine-grained identification of repetitive behaviors. The RBQ was employed to examine repetitive behavior in Angelman (N = 104), Cornelia de Lange (N = 101), Cri-du-Chat…

  10. The prevalence, aetiology and management of wounds in a community care area in Ireland.

    LENUS (Irish Health Repository)

    Skerritt, Louise


    This study aimed to establish the prevalence and aetiology of wounds, allowing an insight into the management of wound care, the use of dressings and the nursing time allocated to the provision of wound care in a community setting in Ireland. A cross-sectional survey was used, with data collected on all clients in the community who received treatment from public health nurses or community registered general nurses for wound care over a 1-week period in April 2013. A 98.9% response rate was realised, and 188 people were identified as having wounds, equating to a crude prevalence of 5% of the active community nursing caseload. A total of 60% (n=112) had leg ulcers, 22% (n=42) had pressure ulcers, 16% (n=30) had an acute wound (surgical or traumatic wounds), 1% (n=2) had a diabetic foot wound and a further 1% (n=2) had wounds of other aetiologies. The mean duration of wounds was 5.41 months. A total of 18% of wounds were identified as infected; however, 60% (n=112) of wounds had antimicrobial products in use as either a primary or secondary dressing. The study established that there is a significant prevalence of wounds in this community care area. There was absence of a clinical diagnosis in many cases, and evidence of inappropriate dressing use, risking an increase in costs and a decrease in good clinical outcomes. It also highlighted the importance of ongoing education and auditing in the provision of wound care.

  11. A systematic review of personality disorder, race and ethnicity: prevalence, aetiology and treatment

    Directory of Open Access Journals (Sweden)

    Lee Tennyson


    Full Text Available Abstract Background Although psychoses and ethnicity are well researched, the importance of culture, race and ethnicity has been overlooked in Personality Disorders (PD research. This study aimed to review the published literature on ethnic variations of prevalence, aetiology and treatment of PD. Method A systematic review of studies of PD and race, culture and ethnicity including a narrative synthesis of observational data and meta-analyses of prevalence data with tests for heterogeneity. Results There were few studies with original data on personality disorder and ethnicity. Studies varied in their classification of ethnic group, and few studies defined a specific type of personality disorder. Overall, meta-analyses revealed significant differences in prevalence between black and white groups (OR 0.476, CIs 0.248 - 0.915, p = 0.026 but no differences between Asian or Hispanic groups compared with white groups. Meta-regression analyses found that heterogeneity was explained by some study characteristics: a lower prevalence of PD was reported among black compared with white patients in UK studies, studies using case-note diagnoses rather than structured diagnostic interviews, studies of borderline PD compared with the other PD, studies in secure and inpatient compared with community settings, and among subjects with co-morbid disorders compared to the rest. The evidence base on aetiology and treatment was small. Conclusion There is some evidence of ethnic variations in prevalence of personality disorder but methodological characteristics are likely to account for some of the variation. The findings may indicate neglect of PD diagnosis among ethnic groups, or a true lower prevalence amongst black patients. Further studies are required using more precise cultural and ethnic groups.

  12. Jung's views on causes and treatments of schizophrenia in light of current trends in cognitive neuroscience and psychotherapy research I. Aetiology and phenomenology. (United States)

    Silverstein, Steven M


    Jung's writings on schizophrenia are almost completely ignored or forgotten today. The purpose of this paper, along with a follow-up article, is to review the primary themes found in Jung's writings on schizophrenia, and to assess the validity of his theories about the disorder in light of our current knowledge base in the fields of psychopathology, cognitive neuroscience and psychotherapy research. In this article, five themes related to the aetiology and phenomenology of schizophrenia from Jung's writings are discussed:1) abaissement du niveau mental; 2) the complex; 3) mandala imagery; 4) constellation of archetypes and 5) psychological versus toxic aetiology. Reviews of the above areas suggest three conclusions. First, in many ways, Jung's ideas on schizophrenia anticipated much current thinking and data about the disorder. Second, with the recent (re)convergence of psychological and biological approaches to understanding and treating schizophrenia, the pioneering ideas of Jung regarding the importance of both factors and their interaction remain a useful and rich, but still underutilized resource. Finally, a more concerted effort to understand and evaluate the validity of Jung's concepts in terms of evidence from neuroscience could lead both to important advances in analytical psychology and to developments in therapeutic approaches that would extend beyond the treatment of schizophrenia. © 2014, The Society of Analytical Psychology.

  13. Clinical Presentation, Aetiology, and Outcomes of Meningitis in a Setting of High HIV and TB Prevalence

    Directory of Open Access Journals (Sweden)

    Keneuoe Hycianth Thinyane


    Full Text Available Meningitis causes significant morbidity and mortality globally. The aim of this study was to study the clinical presentation, aetiology, and outcomes of meningitis among adult patients admitted to Queen Mamohato Memorial Hospital in Maseru, Lesotho, with a diagnosis of meningitis. A cross-sectional study was conducted between February and April 2014; data collected included presenting signs and symptoms, laboratory results, and clinical outcomes. Descriptive statistics were used to summarise data; association between variables was analysed using Fisher’s exact test. 56 patients were enrolled; the HIV coinfection rate was 79%. The most common presenting symptoms were altered mental status, neck stiffness, headache, and fever. TB meningitis was the most frequent diagnosis (39%, followed by bacterial (27%, viral (18%, and cryptococcal meningitis (16%. In-hospital mortality was 43% with case fatalities of 23%, 40%, 44%, and 90% for TB, bacterial, cryptococcal, and viral meningitis, respectively. Severe renal impairment was significantly associated with mortality. In conclusion, the causes of meningitis in this study reflect the high prevalence of HIV and TB in our setting. Strategies to reduce morbidity and mortality due to meningitis should include improving diagnostic services to facilitate early detection and treatment of meningitis and timely initiation of antiretroviral therapy in HIV-infected patients.

  14. Clinical Presentation, Aetiology, and Outcomes of Meningitis in a Setting of High HIV and TB Prevalence (United States)

    Thinyane, Keneuoe Hycianth; Motsemme, Keanole Mofona; Cooper, Varsay Jim Lahai


    Meningitis causes significant morbidity and mortality globally. The aim of this study was to study the clinical presentation, aetiology, and outcomes of meningitis among adult patients admitted to Queen Mamohato Memorial Hospital in Maseru, Lesotho, with a diagnosis of meningitis. A cross-sectional study was conducted between February and April 2014; data collected included presenting signs and symptoms, laboratory results, and clinical outcomes. Descriptive statistics were used to summarise data; association between variables was analysed using Fisher's exact test. 56 patients were enrolled; the HIV coinfection rate was 79%. The most common presenting symptoms were altered mental status, neck stiffness, headache, and fever. TB meningitis was the most frequent diagnosis (39%), followed by bacterial (27%), viral (18%), and cryptococcal meningitis (16%). In-hospital mortality was 43% with case fatalities of 23%, 40%, 44%, and 90% for TB, bacterial, cryptococcal, and viral meningitis, respectively. Severe renal impairment was significantly associated with mortality. In conclusion, the causes of meningitis in this study reflect the high prevalence of HIV and TB in our setting. Strategies to reduce morbidity and mortality due to meningitis should include improving diagnostic services to facilitate early detection and treatment of meningitis and timely initiation of antiretroviral therapy in HIV-infected patients. PMID:26491454

  15. Viral and bacterial aetiologies of male urethritis: findings of a high prevalence of Epstein-Barr virus. (United States)

    Berntsson, M; Löwhagen, G-B; Bergström, T; Dubicanac, L; Welinder-Olsson, C; Alvengren, G; Tunbäck, P


    Male urethritis is one of the most common sexually transmitted infections (STIs). However, the aetiology is still unclear in many cases. In this study the prevalences of Epstein-Barr virus (EBV), herpes simplex virus type 1 (HSV-1), HSV-2, cytomegalovirus (CMV), adenovirus, Chlamydia trachomatis, Mycoplasma genitalium and Ureaplasma urealyticum (including subtyping) were investigated. Samples from 112 male STI attendants with microscopically verified urethritis and from a control group of 103 men without clinical or microscopic signs of urethritis were analysed. Prevalences in the urethritis group compared with the controls were as follows: EBV 21%, 6% (P urethritis and may play a role in its pathogenesis.

  16. Aetiology of male urethritis in patients recruited from a population with a high HIV prevalence.

    NARCIS (Netherlands)

    Sturm, P.D.J.; Moodley, P.; Khan, N.; Ebrahim, S.; Govender, K.; Connolly, C.E.; Sturm, A.W.


    The aetiology of urethritis, the significance of potential pathogens and the relation of urethritis to HIV infection were determined in 335 men (cases) with and 100 men (controls) without urethral symptoms. Urethral swab specimens were tested for different organisms by PCR or by culture for

  17. Clinical Presentation, Aetiology, and Outcomes of Meningitis in a Setting of High HIV and TB Prevalence


    Thinyane, Keneuoe Hycianth; Motsemme, Keanole Mofona; Cooper, Varsay Jim Lahai


    Meningitis causes significant morbidity and mortality globally. The aim of this study was to study the clinical presentation, aetiology, and outcomes of meningitis among adult patients admitted to Queen Mamohato Memorial Hospital in Maseru, Lesotho, with a diagnosis of meningitis. A cross-sectional study was conducted between February and April 2014; data collected included presenting signs and symptoms, laboratory results, and clinical outcomes. Descriptive statistics were used to summarise ...

  18. Leisure Sickness : A pilot study on its Prevalence, Phenomenology, and Background

    NARCIS (Netherlands)

    Vingerhoets, A.J.J.M.; van Huijgevoort, M.; van Heck, G.L.


    Aim: To explore the prevalence, phenomenology, and background of leisure sickness, i.e., the condition of people developing symptoms of sickness during weekends and/or vacations. Method: In order to obtain an estimate of its prevalence, a representative Dutch sample consisting of 1,128 men and 765

  19. Self-Injurious Behaviour in Cornelia De Lange Syndrome: 1. Prevalence and Phenomenology (United States)

    Oliver, C.; Sloneem, J.; Hall, S.; Arron, K.


    Background: Self-injurious behaviour is frequently identified as part of the behavioural phenotype of Cornelia de Lange syndrome (CdLS). We conducted a case-control study of the prevalence and phenomenology of self-injurious behaviour (SIB) in CdLS. Methods: A total of 54 participants with CdLS were compared with 46 individuals who were comparable…

  20. Prevalence of autism spectrum disorder phenomenology in genetic disorders: a systematic review and meta-analysis. (United States)

    Richards, Caroline; Jones, Christopher; Groves, Laura; Moss, Jo; Oliver, Chris


    Autism spectrum disorder (ASD) phenomenology is reported to be more common in individuals with some genetic syndromes than in the general population; however, no meta-analysis has provided prevalence data within and between syndromes. In this systematic review and meta-analysis, we aimed to synthesise data from a wide range of papers to provide accurate estimates about ASD phenomenology in genetic and metabolic syndromes. We identified syndromes reported as most likely to be associated with ASD. We searched Ovid PsycINFO, Ovid MEDLINE, Ovid Embase, and PubMed Central for English-language papers published from database creation up to early 2014 with use of syndrome-specific keywords and a set of ASD keywords. We screened and extracted papers that had ASD prevalence data for ten or more people within a genetic syndrome. With use of a prespecified set of reliable criteria, we applied quality weighting to papers and estimated a quality-effects prevalence of ASD phenomenology for each syndrome. We then calculated relative risks to compare ASD between all syndromes and also calculated odds ratios to compare prevalence with the general population taking the current estimate of one in 68 people. We identified 168 papers reporting the prevalence of ASD phenomenology and found widely varying methods and quality of data. Quality-weighted effect prevalence estimates of ASD phenomenology were established for Rett's syndrome (female individuals only 61%), Cohen's syndrome (54%), Cornelia de Lange syndrome (43%), tuberous sclerosis complex (36%), Angelman's syndrome (34%), CHARGE syndrome (30%), fragile X syndrome (male individuals only 30%; mixed sex 22%), neurofibromatosis type 1 (18%), Down's syndrome (16%), Noonan's syndrome (15%), Williams' syndrome (12%), and 22q11.2 deletion syndrome (11%). Relative risks and the odds ratio compared with the general population were highest for Rett's syndrome and Cohen's syndrome. In all syndromes, odds ratios showed ASD phenomenology to

  1. Cervical high-intensity intramedullary lesions in achondroplasia : Aetiology, prevalence and clinical relevance

    NARCIS (Netherlands)

    Brouwer, Patrick A.; Lubout, Charlotte M.; van Dijk, J. Marc C.; Vleggeert-Lankamp, Carmen L.


    In achondroplastic patients with slight complaints of medullary compression the cervical spinal cord regularly exhibits an intramedullary (CHII) lesion just below the craniocervical junction with no signs of focal compression on the cord. Currently, the prevalence of the lesion in the general

  2. Prevalence and aetiology of Molar-Incisor Hypomineralisation among children aged 8-10 years in Tirana, Albania. (United States)

    Hysi, D; Kuscu, O O; Droboniku, E; Toti, C; Xhemnica, L; Caglar, E


    Molar incisor hypomineralisation (MIH) describes the clinical appearance of enamel hypomineralisation of systemic origin affecting one or more permanent first molars (PFMs) that are frequently associated with affected incisors. The aim of this study was to investigate the prevalence and aetiology of MIH in children living in Tirana, Albania. The study was conducted at the Department of Paediatric and Preventive Dentistry, Faculty of Dental Medicine, and Tirana Dental Public Health Service. A total of 1,575 school children aged 8-10 years were examined by 7 calibrated examiners (dentists) (kappa: 0.86). The Weerheijm criteria were used for the diagnosis of demarcated opacities, post-eruption breakdown, atypical restorations, and extracted PFMs due to MIH. Prevalence of MIH was found to be 14% (n=227). In the 227 children with MIH, tooth 36 was the most affected PFM, and tooth 46 the least affected. Tooth 21 was the most affected incisor and tooth 32 the least affected incisor by MIH. MIH(+) children had significanly more childhood diseases in the first 3 years of life (p=0.006). Among the children who used antibiotics, MIH(+) cases were 1.41 (1.06-1.87) times higher than in children who did not usedantibiotics, MIH(-) cases. MIH was found to be common among 8-10 year-old Tirana children.

  3. Lower urinary tract symptoms in Parkinson's disease: Prevalence, aetiology and management. (United States)

    McDonald, Claire; Winge, Kristian; Burn, David J


    Lower urinary tract symptoms (LUTS) are common in Parkinson's disease (PD), effecting 27-85% of patients with PD. Irritative symptoms predominate and urodynamic studies confirm high prevalence of detrusor overactivity in PD. LUTS are present early in PD and are more common in PD than in age matched controls. The assessment of LUTS in PD is complicated by coexisting bradykinesia and cognitive impairment. Although LUTS become more troublesome as PD progresses it remains unclear if LUTS severity correlates with motor symptoms and/or duration of PD. The underlying cause of LUTS in PD remains to be fully elucidated. Animal and human studies suggest the net effect of the basal ganglia is to supress micturition. Although LUTS are a common in PD, few studies have examined the assessment and management of LUTS specifically in patients with PD. Pilot studies have suggested that bladder training, antimuscarinic drugs and intravesical botulinum toxin maybe helpful but these trials have been small and frequently lacked a suitable control group making them vulnerable to the placebo effect. Furthermore the adverse effects of antimuscarinic drugs on cognitive and gastrointestinal function may limit the use of these drugs in PD. In this review we summarise the literature describing the prevalence of LUTS in PD, discuss the emerging data delineating the underlying pathophysiology of LUTS and examine interventions helpful in the management of LUTS in people with PD. Copyright © 2016. Published by Elsevier Ltd.

  4. Phantom testis syndrome: prevalence, phenomenology and putative mechanisms. (United States)

    Pühse, Gerald; Wachsmuth, Julia Urte; Kemper, Sebastian; Husstedt, Ingo W; Kliesch, Sabine; Evers, Stefan


    Chronic phantom pain has been found in up to 78% of limb amputees and is a major complication of limb amputation. Less is known about phantom phenomena after the amputation of other, i.e. visceral, parts of the body. In a retrospective design, we identified 539 patients in whom one testis was removed between 1995 and 2005. The operative technique was a unilateral standard radical inguinal orchiectomy. The underlying pathology in all cases was a testicular germ cell tumour. All patients received a detailed questionnaire asking about the occurrence of phantom testis pain (pain felt in the removed testis), phantom testis sensations (non-painful sensations as if the removed testis was still intact) and hallucinations (illusionary perceptions on the removed testis). Furthermore, we asked about the occurrence and clinical presentation of pain before and after surgery and about pre-operative testicular pain. Out of 238 respondents, 125 patients (53%) reported any kind of phantom experience. The prevalence of phantom testis pain was 25% (60/238), non-painful phantom sensations 16% (37/238) and male gonad hallucinations 12% (28/238). Patients with phantom symptoms reported pre-operative pain in the removed testis more often than patients without phantom symptoms. This study presents first data on the clinical characteristics and possible mechanisms of the phantom testis syndrome after surgical removal of one testis.

  5. Bovine paramphistomosis in Galicia (Spain): prevalence, intensity, aetiology and geospatial distribution of the infection. (United States)

    González-Warleta, Marta; Lladosa, Silvia; Castro-Hermida, José Antonio; Martínez-Ibeas, Ana María; Conesa, David; Muñoz, Facundo; López-Quílez, Antonio; Manga-González, Yolanda; Mezo, Mercedes


    The present study explored various basic aspects of the epidemiology of paramphistomosis in Galicia, the main cattle producing region in Spain. In total, 589 cows from different farms located across the region were selected at random in the slaughterhouse for examination of the rumens and reticula for the presence of Paramphistomidae flukes. Paramphistomes were found in 111 of 589 necropsied cows (18.8%; 95% CI: 15.7-21.9%), with higher prevalences of infection in beef cows than in dairy cows (29.2% vs 13.9%). Although the number of flukes per animal was generally low (median=266 flukes), some cows harboured large parasite burdens (up to 11,895 flukes), which may have harmful effects on their health or productivity. Cows with higher parasite burdens also excreted greater numbers of fluke eggs in their faeces, which suggests that heavily parasitized mature cows play an important role in the transmission of paramphistomosis. This role may be particularly important in Galicia, where the roe deer, which is the only wild ruminant in the study area, was found not to be a reservoir for the infection. The use of morpho-anatomical and molecular techniques applied to a large number of fluke specimens provided reliable confirmation that Calicophoron daubneyi is the only species of the family Paramphistomidae that parasitizes cattle in Galicia. The environmental data from the farms of origin of the necropsied cows were used in Bayesian geostatistical models to predict the probability of infection by C. daubneyi throughout the region. The results revealed the role of environmental risk factors in explaining the geographical heterogeneity in the probability of infection in beef and dairy cattle. These explanatory factors were used to construct predictive maps showing the areas with the highest predicted risk of infection as well as the uncertainty associated with the predictions. Copyright © 2012 Elsevier B.V. All rights reserved.

  6. Self-injurious behaviour in Cornelia de Lange syndrome: 1. Prevalence and phenomenology. (United States)

    Oliver, C; Sloneem, J; Hall, S; Arron, K


    Self-injurious behaviour is frequently identified as part of the behavioural phenotype of Cornelia de Lange syndrome (CdLS). We conducted a case-control study of the prevalence and phenomenology of self-injurious behaviour (SIB) in CdLS. A total of 54 participants with CdLS were compared with 46 individuals who were comparable on key variables including age, degree of intellectual disability and wheelchair use, using questionnaire and observational measures. Clinically significant self-injury was not more prevalent in the CdLS group (55.6%), nor was it different in presentation from that seen in the comparison group. Hyperactivity, stereotyped and compulsive behaviours predicted clinically significant self-injury in all participants. Hand directed, mild self-injury was more prevalent in CdLS. The results show that clinically significant self-injury may not be part of the behavioural phenotype of CdLS but a specific body target for proto-SIB is more common.

  7. [Capgras delusion: a review of aetiological theories]. (United States)

    Madoz-Gúrpide, Agustín; Hillers-Rodríguez, Rosalía


    Features of the Capgras delusion, the most common among the delusional misidentification syndromes, are reviewed. We describe its phenomenology in psychiatric and organic diseases, its prevalence and comorbidity with other reduplicative disorders and review aetiological models in order to elucidate the origins of the delusion from both the cognitive psychology and psychodynamics precepts, as the neuropsychiatry and anatomical basis. According to cognitive models, Capgras syndrome cannot be exclusively conceived as a dysfunction in facial recognition but in recognizing a person globally considered. Feeling of familiarity is absent due to the inability to integrate successive memories about a person along episodic experiences, thus generating delusional doubles in accordance to the patient's needs or drives. From the neuropsychiatry point of view Capgras delusion arises from the failure in reconciling information about identification of the person and its associated emotions by the disconnection between frontal lobes and right temporo-limbic regions (hippocampus), in addition to bilateral frontal damage. Delusions are more commonly associated with right hemisphere lesions because of the impairment of several functions such as self monitoring, reality monitoring, memory and feelings of familiarity as well as the necessary preservation of the left hemisphere. Aetiology of Capgras delusion should include the conjoint involvement of clinical, neuropsychiatric and neuropsychological data with different theoretical models.

  8. Domestic violence in patients visiting general practitioners--prevalence, phenomenology, and association with psychopathology. (United States)

    Marais, A; de Villiers, P J; Möller, A T; Stein, D J


    It has been suggested that domestic violence is not only highly prevalent and associated with significant morbidity, but that it is also overlooked by medical practitioners. Despite this, few studies have focused on domestic violence in the South African setting, so that there is a paucity of data here on its prevalence, phenomenology, and associated psychopathology. Sixteen general practitioners from the South African Sentinel Practitioner Research Network (SASPREN) screened all their female patients aged 18 years or older for a 3-month period (N = 1,050). A sociodemographic questionnaire was completed, and symptoms of post-traumatic stress disorder (PTSD) and major depression were assessed, both in subjects with a history of domestic violence and in a control group without such a history. 21.5% of patients reported a history of domestic violence at screening. Patients and controls did not differ significantly in terms of age or race. However, patients with a history of domestic violence were significantly more likely to be married, not to have begun a high-school education, and to be working outside the home. Both PTSD and major depression were significantly more common in patients with a history of domestic violence (35.3% and 48.2%, respectively) than in controls (2.6% and 11.4%, respectively). Compared with other patients reporting domestic violence, those with either PTSD or major depression were subjected to more violence and were more likely to report a suicide attempt. In a large, diverse population of adult female patients presenting to a range of general practitioners in South Africa, there was a high prevalence of reported domestic violence. A significant association was found between domestic violence and both PTSD and major depression, with these diagnoses indicative of increased severity of abuse and increased morbidity. Routine screening by medical practitioners of all female patients for a history of domestic violence seems warranted, and patients

  9. Leisure sickness: a pilot study on its prevalence, phenomenology, and background. (United States)

    Vingerhoets, Ad J J M; Van Huijgevoort, Maaike; Van Heck, Guus L


    To explore the prevalence, phenomenology, and background of leisure sickness, i.e., the condition of people developing symptoms of sickness during weekends and/or vacations. In order to obtain an estimate of its prevalence, a representative Dutch sample consisting of 1,128 men and 765 women was asked to indicate to what extent they recognized themselves in our description of weekend and vacation sickness. For the investigation of the phenomenology and background of this condition and the characteristics of the patients suffering from it, questionnaire data were collected in new samples consisting of 114 cases and 56 controls. Questions referred to symptoms, onset, duration, appreciation of weekend and vacation activities, and appraisal of work and workload. In the case of male respondents, 3.6 and 3.2% recognized themselves in the description of the weekend and the vacation syndrome, respectively, compared with 2.7 and 3.2% women. Most frequently reported symptoms were headache/migraine, fatigue, muscular pains, and nausea. In addition, viral infections (flue-like, common cold) were often reported in relation to vacations. Cases had generally suffered from leisure sickness for over 10 years and the onset was associated with stressful conditions. They attributed their condition to difficulties with the transition from work to nonwork, stress associated with travel and vacation, as well as workload and personality characteristics. There were no significant group differences in the appreciation of weekend and leisure activities or lifestyle during days off. Most striking differences were found with respect to experienced workload, sense of responsibility, and inability to relax. Leisure sickness is a relatively common condition. Specific lifestyle factors or leisure activities seem to be less relevant for its development. Concerning risk factors, the data tend to point to high workload and person characteristics, namely, the inability to adapt to the nonworking

  10. Iron deficiency anaemia in pre-school (1- 6 years) in Al Shigla area (Khartoum State) :Prevalence and Aetiology

    International Nuclear Information System (INIS)

    Osman, Faiza Mohamed


    iron deficiency anaemia (IDA) is a public health problem throughout the world. Childhood iron deficiency anaemia. A prospective survey (systematic, cluster sampling) was carried out among pre-school children in Alshigla area (Khartoum State), to study the prevalence and aetological factors of IDA. 170 children selected for general nutritional evaluation, 110 of them for haemoglobin levels and morphological classification of anaemia, 70 for further investigations(serum iron, unsaturated iron binding capacity, total iron binding capacity). The population at Alshigla were living in poor condition 85.3% relied on water brought by tankers which showed poor hygienic standard, 90% lived in extended families 54.1% had income level less than LS 3000/day irrespective of family size or mode of spending. A sample of 170 children showed (84.1%) normal nutritional status with 4.7% severe cases with high consumption of cereals low meat, fish and poultry group and vitamin C(22.9%). Disease episodes showed 67.7% had diarrhoea, 22.4% had giardia, 12.9% had malaria and 10.6% had worm infestation. This most probably due to unsanitary living condition. Haemoglobin analysis using Enzyme Linked Immunosorbent assay technique (ELISA) for 110 of the children, showed high prevalence of anaemia (96.4%), 66% prevalence of IDA. Further haematological investigations of 50 of the children confirmed them as IDA cases.Thus the high prevalence of IDA in Alshigla was multi-factorial, inadequate take of dietary iron and of vitamin C, high intake of cereals and legumes, low intake of meat, poultry and fish group (MPF),and high tea consumption, thus food provides inadequate supply of iron and were rich in inhibitors of iron absorption. In addition episodes of diseases that may influence food (hence iron) utilisation contributed to the prevalence of IDA

  11. Symptoms and aetiology of delirium: a comparison of elderly and adult patients. (United States)

    Grover, S; Agarwal, M; Sharma, A; Mattoo, S K; Avasthi, A; Chakrabarti, S; Malhotra, S; Kulhara, P; Bas, D


    OBJECTIVE. To compare the symptoms of delirium as assessed by the Delirium Rating Scale-Revised-98 (DRS-R-98) and associated aetiologies in adult and elderly patients seen in a consultation-liaison service. METHODS. A total of 321 consecutive patients with a DSM-IV-TR diagnosis of delirium were assessed on the DRS-R-98 and a study-specific aetiology checklist. RESULTS. Of the 321 patients, 245 (76%) aged 18 to 64 years formed the adult group, while 76 (24%) formed the elderly group (≥ 65 years). The prevalence and severity of various symptoms of delirium as assessed using the DRS-R-98 were similar across the 2 groups, except for the adult group having statistically higher prevalence and severity scores for thought process abnormalities and lability of affect. For both groups and the whole sample, factor analysis yielded a 3-factor model for the phenomenology. In the 2 groups, the DRS-R-98 item loadings showed subtle differences across various factors. The 2 groups were similar for the mean number of aetiologies associated with delirium, the mean number being 3. However, the 2 groups differed with respect to hepatic derangement, substance intoxication, withdrawal, and postpartum causes being more common in the adult group, in contrast lung disease and cardiac abnormalities were more common in the elderly group. CONCLUSION. Adult and elderly patients with delirium are similar with respect to the distribution of various symptoms, motor subtypes, and associated aetiologies.

  12. Prevalence and phenomenology of eye tics in Gilles de la Tourette syndrome. (United States)

    Martino, Davide; Cavanna, Andrea E; Robertson, Mary M; Orth, Michael


    Eye tics seem to be common in Gilles de la Tourette syndrome (GTS). We analyzed the frequency and clinical characteristics of eye tics in 212 GTS patients. Of the 212 patients, 201 (94.8 %) reported eye tics in their life-time; 166 (78.3 %) reported eye movement tics (rolling eyes up/down, eyes looking sideways, staring), and 194 (91.5 %) eyelid/eyebrow movement tics (frowning, raising eyebrows, blinking or winking). Patients with eye movement tics were younger at age of GTS onset (7.1 ± 4 years) than those without (8.9 ± 6.8; p = 0.024). Tic severity positively correlated to lifetime history of eye and/or eyelid/eyebrow movement tics. Our data confirm that eye and eyelid/eyebrow movement tics are very common in GTS, and most patients have several types of eye tics over time. Eye tic phenomenology was similar in patients with or without co-morbidity. Eye tics are therefore likely to be a core feature of GTS and should be routinely evaluated in order to strengthen the clinician's confidence in diagnosing GTS.

  13. Anxiety in individuals with ASD: Prevalence, phenomenology, etiology, assessment, and interventions

    NARCIS (Netherlands)

    van Steensel, F.J.A.; Bögels, S.M.; Magiati, I.; Perrin, S.; Patel, V.B.; Preedy, V.R.; Martin, C.R.


    ndividuals with autism spectrum disorder (ASD) experience high levels of anxiety symptomatology with an estimated prevalence rate of anxiety disorders as high as 40 %. It is likely that anxiety is prominent in individuals with ASD throughout the life-span and that factors such as age, IQ, and ASD

  14. Prevalence and phenomenology of neonaticide in Switzerland 1980-2010: a retrospective study. (United States)

    Krüger, Paula


    For a child, the likelihood of being murdered is highest during the first year of life, and many such cases are neonaticides. Although several recent studies have examined neonaticide in different countries and cultures, there has been no in-depth analysis of Swiss cases, even though this country has special neonaticide legislation and four "baby hatches" have been opened to prevent such killings. The primary objective of this retrospective study was to analyze the prevalence and phenomenon of neonaticide in Switzerland. Using data from judicial files, 11 cases were identified in 15 German-speaking cantons between 1980 and 2010. The sample included two uncommon cases of nonmaternal neonaticide. The discussion addresses possible prevention strategies.

  15. Cohort study of prevalence and phenomenology of tremor in dementia with Lewy bodies. (United States)

    Onofrj, Marco; Varanese, Sara; Bonanni, Laura; Taylor, John-Paul; Antonini, Angelo; Valente, Enza Maria; Petrucci, Simona; Stocchi, Fabrizio; Thomas, Astrid; Perfetti, Bernardo


    To study prevalence, specific patterns and response to treatment of tremor in dementia with Lewy bodies (DLB), in comparison with other tremulous disorders prevalence, qualitative and quantitative features of tremor were studied in an incident cohort of 67 dopaminergic treatment naive DLB, 111 Parkinson's Disease (PD) and 34 Essential Tremor (ET) patients. Tremulous DLB patients (tDLB) were compared with tremulous PD (tPD) and ET patients and followed for 2 years. Double blind placebo-controlled acute drug challenge with L-Dopa and alcohol was performed in all ET, 24 tDLB and 27 tPD. Effects of dopaminergic chronic treatment in all tDLB and tPD patients and primidone in 8 tDLB were also assessed. Tremor occurred in 44.76 % of DLB patients. The tDLB patients presented a complex pattern of mixed tremors, characterized by rest and postural/action tremor, including walking tremor and standing overflow in 50 % tDLB. Standing tremor with overflow was characteristic of tDLB (p < 0.001). Head tremor was more frequent in tDLB than tPD and ET (p = 0.001). The tDLB tremors were reduced by acute and chronic dopaminergic treatments (p < 0.01) but not by alcohol or primidone. Tremor occurs commonly in DLB patients with a complex mixed tremor pattern which shows a significant response to acute and chronic dopaminergic treatments. Recognizing that there is a clinical category of tremulous DLB may help the differential diagnosis of tremors.

  16. Schizophrenia : Current concepts in aetiology

    Directory of Open Access Journals (Sweden)

    P S Bhat


    Full Text Available Schizophrenia is perhaps the most devastating neuropsychiatric illness. Worldwide, its prevalence rate is about 1%. Schizophrenia is considered a neurodevelopmental disorder involving the interplay of susceptibility genes and environmental factors. There is a wide range of pathologic findings, but there is no specific or diagnostic laboratory abnormality. Till date, the aetiology, neuropathology, and pathophysiology of schizophrenia remain elusive. Over the last forty years, the dopaminergic model has been the leading neurochemical hypothesis of schizophrenia. Yet it remains unlikely that dopaminergic dysfunction, on its own. Glutamatergic models provide an alternate approach for conceptualizing the brain abnormalities associated with schizophrenia. New pharmacological and behavioral approaches aimed at potentiating glutamatergic neurotransmission, offer new hopeforfuture clinical development

  17. The Phenomenology of Emotion Experience in First-Episode Psychosis

    DEFF Research Database (Denmark)

    Vodušek, V V; Parnas, J; Tomori, M


    BACKGROUND: Although it has been suggested that disturbances in emotion experience and regulation play a central role in the aetiology and psychopathology of schizophrenia spectrum disorders, the phenomenology of emotion experience in schizophrenia remains under-researched. SAMPLING AND METHODS: ...

  18. Global variations and time trends in the prevalence of childhood myopia, a systematic review and quantitative meta-analysis: implications for aetiology and early prevention. (United States)

    Rudnicka, Alicja R; Kapetanakis, Venediktos V; Wathern, Andrea K; Logan, Nicola S; Gilmartin, Bernard; Whincup, Peter H; Cook, Derek G; Owen, Christopher G


    The aim of this review was to quantify the global variation in childhood myopia prevalence over time taking account of demographic and study design factors. A systematic review identified population-based surveys with estimates of childhood myopia prevalence published by February 2015. Multilevel binomial logistic regression of log odds of myopia was used to examine the association with age, gender, urban versus rural setting and survey year, among populations of different ethnic origins, adjusting for study design factors. 143 published articles (42 countries, 374 349 subjects aged 1-18 years, 74 847 myopia cases) were included. Increase in myopia prevalence with age varied by ethnicity. East Asians showed the highest prevalence, reaching 69% (95% credible intervals (CrI) 61% to 77%) at 15 years of age (86% among Singaporean-Chinese). Blacks in Africa had the lowest prevalence; 5.5% at 15 years (95% CrI 3% to 9%). Time trends in myopia prevalence over the last decade were small in whites, increased by 23% in East Asians, with a weaker increase among South Asians. Children from urban environments have 2.6 times the odds of myopia compared with those from rural environments. In whites and East Asians sex differences emerge at about 9 years of age; by late adolescence girls are twice as likely as boys to be myopic. Marked ethnic differences in age-specific prevalence of myopia exist. Rapid increases in myopia prevalence over time, particularly in East Asians, combined with a universally higher risk of myopia in urban settings, suggest that environmental factors play an important role in myopia development, which may offer scope for prevention. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to

  19. Understanding phenomenology.

    LENUS (Irish Health Repository)

    Flood, Anne


    Phenomenology is a philosophic attitude and research approach. Its primary position is that the most basic human truths are accessible only through inner subjectivity, and that the person is integral to the environment. This paper discusses the theoretical perspectives related to phenomenology, and includes a discussion of the methods adopted in phenomenological research.

  20. [Aetiology of childhood alopecia]. (United States)

    Cortés G, Andrea; Mardones V, Felipe; Zemelman D, Viviana


    Childhood alopecia is a relative rare event in general paediatric dermatology practice. Hair loss in children may have multiple causes, and there are different types of alopecia according to age groups. The aim of the study was to describe the clinical and epidemiological profile of alopecia in children from two Chilean paediatric hospitals. Descriptive analysis of clinical records of patients from the Dermatology Department of Roberto del Rio and Luis Calvo Mackenna Hospitals between January 2007 and June 2010. Patients with clinical diagnosis of alopecia were included. A total of 345 clinical records were analysed, with 179 males (51.9%). The median age was 72 months. Overall, the most common diagnoses were: alopecia areata (AA), (36.8%), tinea capitis (TC), (21%), nevus sebaceous (13.2%), and tellogen effluvium (8.7%). According to age groups, in newborns, the most common causes were aplasia cutis and nevus sebaceous. In toddlers, pre-school and school children, the principal causes were nevus sebaceous, AA and TC. Trichotillomania was also significant in school children. In adolescents, nevus sebaceous, AA and tellogen effluvium were the most frequent diagnoses. AA was statistically associated with autoimmune disease, thyroid disease, nail disorder, psychiatric disease, and Down's syndrome. The most common aetiological agent in TC was M. canis (86.6%). Trichotillomania was also statistically associated to psychiatric disorders. In this study, the main causes of alopecia in children were acquired and non-scarring alopecia. In our results, the type of alopecia varies according to age group. Some types of childhood alopecia showed a close correlation to psychiatric disorders. Copyright © 2015 Sociedad Chilena de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved.

  1. [Prevalence and Phenomenology of Psychotic-Like Symptoms in Borderline Personality Disorders - Associations with Suicide Attempts and Use of Psychiatric Inpatient Treatment]. (United States)

    Schroeder, Katrin; Schätzle, Anja; Kowohl, Pauline; Leske, Lisa; Huber, Christian G; Schäfer, Ingo


    Psychotic-like symptoms are found in a subgroup of borderline patients (BPD). Reported prevalence is heterogeneous (up to 50% affected). Investigations in Germany have not been conducted so far. Furthermore, the precise phenomenology of the psychotic symptoms and the effects on suicidal behavior and the use of inpatient psychiatric treatment are unclear. The aim of the study was to investigate prevalence rates and phenomenology of psychotic-like symptoms. Associations between the latter and suicidality as well as the use of inpatient psychiatric treatment were examined. Further influencing factors were taking into account. Psychotic-like symptoms were assessed with the Structured Clinical Interview-I in 95 BPD patients. To investigate the associations between psychotic-like symptoms and suicidality as well as the use of inpatient psychiatric treatment, correlation and regression analyzes were calculated, considering severity of PTSD, BPD and depression. 36% of the patients reported alterations of perception and 21% delusions, both multiform and long lasting. The number of suicide attempts was associated with delusions, alterations of perception and severity of PTSD, BPS, and depression. Only delusions and severity of PTSD explained together 25.8% of the variance for the prediction of the number of suicide attempts. Age of initial hospitalization showed fewer and number of hospitalizations no associations at all. Psychotic-like symptoms should not be trivialized, which may happen by using terms such as pseudo-hallucinations or transient paranoid ideas, and may be particularly associated with suicidal tendencies complicating the clinical course. © Georg Thieme Verlag KG Stuttgart · New York.

  2. Phenomenological Lagrangians

    International Nuclear Information System (INIS)

    Weinberg, S.


    The author presents an argument that phenomenological Lagrangians can be used not only to reproduce the soft pion results of current algebra, but also to justify these results, without any use of operator algebra, and shows how phenomenological Lagrangians can be used to calculate corrections to the leading soft pion results to any desired order in external momenta. The renormalization group is used to elucidate the structure of these corrections. Corrections due to the finite mass of the pion are treated and speculations are made about another possible application of phenomenological Lagrangians. (Auth.)

  3. Exceptional phenomenology

    DEFF Research Database (Denmark)

    Aggerholm, Kenneth; Moltke Martiny, Kristian

    Phenomenological research is in traditional terms a matter of going 'back to the things themselves', as Husserl famously stated. But if phenomenology is to renew itself in creative ways and reveal new aspects of human experience it is of value to look for a certain kind of phenomena: exceptions....... Through exceptional cases we can gain a deeper understanding of the ordinary. This was already a guiding thread in Merleau-Ponty’s phenomenological investigations, but this paper will take the idea further by grounding the methodology in ‘hands on’ research in elite sport (football) and pathological cases...... (cerebral palsy). Within this method exceptional phenomena serve as exemplary cases, which can challenge and expand our conception of ”normal” experience. Thus, we will focus on two central aspects of exceptional phenomenology: a) it is grounded in exceptional practice and b) it lets this practical...

  4. EAMJ Aetiology Sep 09.indd

    African Journals Online (AJOL)


    Sep 9, 2009 ... have shown that in many cases the aetiologic agent cannot be identified (3, 4). ... and sanitary practices. All HIV-positive participants ... day. Diarrhoea was treated with oral rehydration solution and, if indicated, antimicrobial and anti- motility agents. Only one stool sample was collected for each episode of ...

  5. String phenomenology

    CERN Document Server

    Ibáñez, Luis E


    This chapter reviews a number of topics in the field of string phenomenology, focusing on orientifold/F-theory models yielding semirealistic low-energy physics. The emphasis is on the extraction of the low-energy effective action and possible tests of specific models at the LHC.

  6. Aetiology of allergic rhinitis in Hong Kong

    Directory of Open Access Journals (Sweden)

    Christopher W.K. Lam


    Full Text Available In a 1993 survey, allergic rhinitis was identified as the most common allergic disease in Hong Kong, affecting 29.1% of schoolchildren. Recently (1995, the International Study of Asthma and Allergies in Childhood (ISAAC also reported 44.5% current rhinitis among Hong Kong teenagers. Our objective was to study the aetiology of allergic rhinitis in Hong Kong using serological tests of allergen sensitization. In 57 allergic rhinitis patients and in the same number of age- and sex-matched controls the following were measured: serum total IgE, mixed aeroallergen IgE (Phadiatop™ and specific IgE versus house dust mite (HDM, cockroach, cat and dog dander, mould mixture (Penicillium, Cladosporium, Aspergillus and Alternaria species and four local pollens (Bermuda grass, Timothy, ragweed and mugwort. Compared with controls, allergic rhinitis patients (26 males, 31 females; mean (± SD age 25 ±11 years had a significantly elevated serum total IgE concentration (mean ± SEM: 496 ± 88 vs 179 ± 38 kU/L and an increased proportion of positive Phadiatop (95 vs 33% and specific IgE tests versus HDM (90 vs 44% and cockroach (42 vs 9%; Mann-Whitney U-test and χ2 tests all P < 0.005. There was no significant difference in sensitization to other allergens tested. House dust mite and cockroach are ubiquitous in Hong Kong with a warm, humid climate and crowded living conditions. Their identification as aetiological agents of allergic rhinitis should help in the development of environmental strategies for reducing the inhalant allergen load to prevent and control this prevalent and costly health problem in our community.

  7. Phenomenology of Joint Attention

    African Journals Online (AJOL)


    might be brought against this analysis. Husserlian Phenomenology. As Husserl explains in Ideas Pertaining to Pure. Phenomenology and to a Phenomenological Philo- sophy (1913/1983), phenomenology is a theory of intentional mental states. A mental state is intentional insofar as it is about some object. The perceptual.

  8. Ovine wet carcass syndrome of unknown aetiology

    African Journals Online (AJOL)

    A condition of unknown aetiology, known as 'the wet sheep carcass syndrome' has led to the loss of about ... aetiology. Introduction. Wet sheep carcasses were seen with increasing frequency at abattoirs from January 1981. ... the holding pens, and transport stress. In the high incidence area (see Figure 1), feeding systems.

  9. Atypical odontalgia. Its aetiology and prognosis. (United States)

    Brooke, R I; Schnurr, R F


    Atypical odontalgia is a chronic pain disorder in which persistent pain develops in clinically normal teeth. Its possible aetiology and long-term prognosis are discussed. Suggested management regimes are reviewed.

  10. Towards a multisensory phenomenology

    DEFF Research Database (Denmark)

    Jensen, Martin Trandberg

    This paper illustrates a multisensory phenomenology that extends hermeneutic phenomenologies in tourism through the embracing of non-representational approaches. The novel co-integration of audio, visual, impressionistic and netnographic accounts allows us to rethink the textual nature and symbolic...... meaning confining phenomenological research. Our analysis is centred on an under-researched European tourism phenomenon, interrailing. This sensuous account provides an original reading of phenomenology focused on how rhythms, sounds and temperatures construct interrail encounters. The analysis...

  11. Aetiology of supernumerary teeth: a literature review. (United States)

    Anthonappa, R P; King, N M; Rabie, A B M


    Supernumerary teeth are teeth, or tooth-like structures that have either erupted or remain unerupted in addition to the 20 primary and 32 permanent teeth. This paper attempts to (a) provide an overview of the proposed hypotheses and the current understanding of the aetiology of supernumerary teeth, and (b) review the published cases of supernumerary teeth occurring in families. No studies have been able to distinguish between different aetiologies for the different locations of supernumerary teeth, while, from a developmental or molecular perspective, the proposed hypotheses may be plausible and explains the origin of different types of supernumerary teeth. The only clearly evident feature, based on the existing published reports, is that it is logical to state that supernumerary teeth have a genetic component in their aetiology.

  12. Anorexia nervosa--diagnosis, aetiology, and treatment. (United States)

    Hartman, D


    The aetiology, assessment and treatment of anorexia nervosa are reviewed in the light of the classical accounts of Morton, Lasègue and Gull. The core symptoms are deliberate weight loss, disturbed body image and amenorrhoea, and complications may include cardiac failure, electrolyte disturbances, hypothermia and osteoporosis. Common clinical findings are described. Disturbed brain serotonin activity is implicated in the aetiology of anorexia nervosa, but there is little support for the use of pharmacological treatments. Psychological theories of aetiology are discussed with reference to Bruch, Crisp, Palazzoli and Minuchin: the common theme is the reaction of the patient and her family to the physical and social changes of puberty. Individual and/or family psychotherapy is seen as central to the treatment of anorexia nervosa, and the relevant clinical research is reviewed. The roles of general practitioners, general psychiatrists and eating disorder specialists are discussed in the light of recent consensus treatment guidelines.

  13. Aetiology and resistance patterns of community-acquired pneumonia in León, Nicaragua

    NARCIS (Netherlands)

    Matute, A J; Brouwer, W P; Hak, E; Delgado, E; Alonso, E; Hoepelman, I M


    We conducted a prevalence study to gain greater insight into the aetiology, bacterial resistance and risk factors for community-acquired pneumonia (CAP) in the region of León, Nicaragua. During the period from July 2002 to January 2005, all consecutive patients with signs and symptoms suggestive of

  14. Phenomenology and homeopathy. (United States)

    Whitmarsh, Tom


    There is a great overlap between the way of seeing the world in clinical homeopathy and in the technical philosophical system known as phenomenology. A knowledge of phenomenologic principles reveals Hahnemann to have been an unwitting phenomenologist. The ideas of phenomenology as applied to medicine show that homeopathy is the ideal medical system to fulfill the goals of coming ever closer to true patient concerns and experience of illness. Copyright © 2013 The Faculty of Homeopathy. Published by Elsevier Ltd. All rights reserved.

  15. Exploring DSM-5 ADHD criteria beyond young adulthood: phenomenology, psychometric properties and prevalence in a large three-decade birth cohort. (United States)

    Vitola, E S; Bau, C H D; Salum, G A; Horta, B L; Quevedo, L; Barros, F C; Pinheiro, R T; Kieling, C; Rohde, L A; Grevet, E H


    There are still uncertainties on the psychometric validity of the DSM-5 attention deficit hyperactivity disorder (ADHD) criteria for its use in the adult population. We aim to describe the adult ADHD phenotype, to test the psychometric properties of the DSM-5 ADHD criteria, and to calculate the resulting prevalence in a population-based sample in their thirties. A cross-sectional evaluation using the DSM-5 ADHD criteria was carried out in 3574 individuals from the 1982 Pelotas Birth Cohort. Through receiver operator curve, latent and regression analyses, we obtained parameters on construct and discriminant validity. Still, prevalence rates were calculated for different sets of criteria. The latent analysis suggested that the adult ADHD phenotype is constituted mainly by inattentive symptoms. Also, inattention symptoms were the symptoms most associated with impairment. The best cut-off for diagnosis was four symptoms, but sensitivity and specificity for this cut-off was low. ADHD prevalence rates were 2.1% for DSM-5 ADHD criteria and 5.8% for ADHD disregarding age-of-onset criterion. The bi-dimensional ADHD structure proposed by the DSM demonstrated both construct and discriminant validity problems when used in the adult population, since inattention is a much more relevant feature in the adult phenotype. The use of the DSM-5 criteria results in a higher prevalence of ADHD when compared to those obtained by DSM-IV, and prevalence would increase almost threefold when considering current ADHD syndrome. These findings suggest a need for further refinement of the criteria for its use in the adult population.

  16. Animal trypanosomiasis in Africa: Aetiology and Epidemiology ...

    African Journals Online (AJOL)

    The aetiology and epidemiology of African trypanosomiasis in bovine species are comprehensively presented. In addition, a critical review o the history and transmission of the disease is exhaustively discussed. The mystery of other epizootiological factors associated with bovine trypanosomiasis is highlighted. Four major ...

  17. Acute Pancreatitis: Demographics, aetiological factors and ...

    African Journals Online (AJOL)

    Introduction. The spectrum of aetiologies and outcomes of acute pancreatitis in South African settings is under-reported. We report our experience at a regional hospital and compare it with international norms. Patients and methods. Data were prospectively collected on all admissions of patients with acute pancreatitis to a ...

  18. Hepatocellular carcinoma in South Sudan: possible aetiologies ...

    African Journals Online (AJOL)

    Hepatocellular carcinoma is one of the common malignancies in both the developed and developing worlds. This is most likely due to its wide variety of causes. The aetiologies vary from one part of the world to another determined by many factors ranging from geography, life style, availability of advanced medical care etc ...

  19. Dynamic bowel obstruction: aetiology, clinical presentation ...

    African Journals Online (AJOL)

    This study was conducted to describe in our region, the aetiology, clinical presentation, management and outcome of dynamic bowel obstruction. Data were analyzed using SPSS software system. A total of 342 patients were studied. Males outnumbered females by a ratio of 2.1: 1. The median age of patients at presentation ...

  20. Dynamic bowel obstruction: aetiology, clinical presentation ...

    African Journals Online (AJOL)

    2005). This makes it essential that studies are made periodically in every region to define the local causes with the idea to do work on their prevention (Adhikari et al., 2010). This study was conducted to describe in our region, the aetiology, clinical presentation, management and outcome of dynamic bowel obstruction.

  1. Incidence, symptomatology and aetiological factors for Asherman's ...

    African Journals Online (AJOL)

    Background: Asherman's syndrome is a significant cause of secondary amenorrhoea and infertility in Nigeria. It is largely preventable and safe practices will make it rare. Aim: To determine the incidence, symptomatology and aetiological factors for Asherman's syndrome in Orlu, South East Nigeria. Methods: A prospective ...

  2. Aetiological blood biomarkers of ischaemic stroke. (United States)

    Sonderer, Julian; Katan Kahles, Mira


    Each year, over 5 million people die worldwide from stroke, and at least every sixth patient who survives will experience another stroke within five years [1]. We are therefore eager to advance early and rapid diagnosis, prognosis and optimal risk stratification, as well as secondary prevention. In this context, blood biomarkers may improve patient care, as they have already done in other fields in the past, for example, troponin T/I in patients with heart attacks, natriuretic peptides in patients with heart failure or PCT (procalcitonin) [2] in patients with pneumonia. In the setting of acute stroke, a blood biomarker can be any quantifiable entity that reflects the manifestation of a stroke-related process. The most fruitful implementation of stroke biomarkers is in areas where information from traditional clinical sources is limited. There may be markers, for example, to guide risk stratification, reveal stroke aetiology, identify patients who may benefit most from interventions, monitor treatment efficacy, and recognise the risk of short-term complications or unfavourable long-term outcomes. For this review we focus on blood biomarkers that could help distinguish the underlying aetiology of an ischaemic stroke. Stroke tends to be a much more heterogeneous condition than ischaemic heart disease, which is caused by atherosclerosis in the vast majority of cases. Causes of stroke include small and large vessel disease, cardioembolism, dissections, and rare vasculo- and coagulopathies, among others. Because of this heterogeneity among stroke patients, it is clear that a monolithic approach to stroke prevention or secondary prevention is not warranted. Aetiological classification is important specifically because prognosis, risk of recurrence and management options differ greatly between aetiological subtypes. Considering that today up to 30% of stroke patients still cannot be classified into a specific subtype [3], the ability to improve aetiological classification

  3. Phenomenology and Meaning Attribution

    African Journals Online (AJOL)

    Phenomenology and Meaning Attribution. John Paley. (2017). Phenomenology as Qualitative Research: A Critical Analysis of Meaning Attribution. London &. New York: Routledge. Hard Cover (198 pages). ...... suggestive power exerted by artistic means of presentation. Thus, if one is fond of paradoxi- cal phrases, one can ...

  4. What Is Film Phenomenology?

    NARCIS (Netherlands)

    Hanich, Julian; Ferencz-Flatz, Christian


    In this article Christian Ferencz-Flatz and I try to give an answer to the question what film phenomenology actually is. We proceed in three steps. First, we provide a survey of five different research practices within current film phenomenological writing: We call them excavation, explanation,

  5. Shifting white pox aetiologies affecting Acropora palmata in the Florida Keys, 1994–2014 (United States)

    Berry, Brett; Park, Andrew; Kemp, Dustin W.; Kemp, Keri M.; Lipp, Erin K.; Porter, James W.


    We propose ‘the moving target hypothesis’ to describe the aetiology of a contemporary coral disease that differs from that of its historical disease state. Hitting the target with coral disease aetiology is a complex pursuit that requires understanding of host and environment, and may lack a single pathogen solution. White pox disease (WPX) affects the Caribbean coral Acropora palmata. Acroporid serratiosis is a form of WPX for which the bacterial pathogen (Serratia marcescens) has been established. We used long-term (1994–2014) photographic monitoring to evaluate historical and contemporary epizootiology and aetiology of WPX affecting A. palmata at eight reefs in the Florida Keys. Ranges of WPX prevalence over time (0–71.4%) were comparable for the duration of the 20-year study. Whole colony mortality and disease severity were high in historical (1994–2004), and low in contemporary (2008–2014), outbreaks of WPX. Acroporid serratiosis was diagnosed for some historical (1999, 2003) and contemporary (2012, 2013) outbreaks, but this form of WPX was not confirmed for all WPX cases. Our results serve as a context for considering aetiology as a moving target for WPX and other coral diseases for which pathogens are established and/or candidate pathogens are identified. Coral aetiology investigations completed to date suggest that changes in pathogen, host and/or environment alter the disease state and complicate diagnosis. PMID:26880837

  6. Shifting white pox aetiologies affecting Acropora palmata in the Florida Keys, 1994-2014. (United States)

    Sutherland, Kathryn P; Berry, Brett; Park, Andrew; Kemp, Dustin W; Kemp, Keri M; Lipp, Erin K; Porter, James W


    We propose 'the moving target hypothesis' to describe the aetiology of a contemporary coral disease that differs from that of its historical disease state. Hitting the target with coral disease aetiology is a complex pursuit that requires understanding of host and environment, and may lack a single pathogen solution. White pox disease (WPX) affects the Caribbean coral Acropora palmata. Acroporid serratiosis is a form of WPX for which the bacterial pathogen (Serratia marcescens) has been established. We used long-term (1994-2014) photographic monitoring to evaluate historical and contemporary epizootiology and aetiology of WPX affecting A. palmata at eight reefs in the Florida Keys. Ranges of WPX prevalence over time (0-71.4%) were comparable for the duration of the 20-year study. Whole colony mortality and disease severity were high in historical (1994-2004), and low in contemporary (2008-2014), outbreaks of WPX. Acroporid serratiosis was diagnosed for some historical (1999, 2003) and contemporary (2012, 2013) outbreaks, but this form of WPX was not confirmed for all WPX cases. Our results serve as a context for considering aetiology as a moving target for WPX and other coral diseases for which pathogens are established and/or candidate pathogens are identified. Coral aetiology investigations completed to date suggest that changes in pathogen, host and/or environment alter the disease state and complicate diagnosis. © 2016 The Author(s).

  7. Car drivers with dementia : different complications due to different aetiologies?

    NARCIS (Netherlands)

    Piersma, D. Waard, D. de Davidse, R. Tucha, O. & Brouwer,W.


    Older drivers with dementia are an at-risk group for unsafe driving. However, dementia refers to various aetiologies and the question is whether dementias of different aetiology have similar effects on driving ability. The literature on the effects of dementia of various aetiologies on driving

  8. Prevalence

    Directory of Open Access Journals (Sweden)

    Ahmed E. Mansour


    Conclusion: The prevalence of spontaneous bacterial pleuritis in the studied group of patients with hepatic hydrothorax was 14.3%. Patients with advanced liver disease, low pleural fluid protein, or SBP are at risk for spontaneous bacterial pleuritis.

  9. New aetiology of patellofemoral pain syndrome. (United States)

    Chas, Julie; Mariot, Philippe; Tassart, Marc; Pialoux, Gilles


    We report the case of a 30-year-old man with more than 100 different male sexual partners per year. He reported using cocaine, ecstasy, γ-hydroxybutyric acid and crystal mephedrone and presented with bilateral gonalgia resistant to standard analgesia. He had no noteworthy medical history, and physical examination and laboratory tests were uninformative. MRI showed marked intra-articular effusion but no meniscus or ligament damage. The aetiological diagnosis in this case was made by excluding other potential causes. Patellofemoral pain syndrome (PFPS) is one of the most common and challenging injuries. In this first case reported, the aetiology was found to be mechanical, due to the position adopted during fellatio with multiple male partners. 2014 BMJ Publishing Group Ltd.

  10. Xerostomia: aetiology and management in cancer patients. (United States)

    Holmes, S


    Although oral complications are common sequelae of cancer/cancer treatment, only sporadic research is published in the literature. It is clear that 'routine' oral hygiene measures are inadequate; a little time and effort may, however, reduce oral discomfort. This is particularly true in the case of xerostomia, which is often thought to be a relatively minor symptom with few deleterious effects. Many patients, however, find xerostomia a significant cause of distress, and for this reason alone, health care professionals require knowledge and appreciation of the pathology and aetiology of the condition and approaches to its management. This paper reviews the physiology of salivation and the aetiology of xerostomia and considers the ways in which the condition can be managed.

  11. Abnormal fetal head shape: aetiology and management

    DEFF Research Database (Denmark)

    Petersen, Olav Bjørn; David, Anna; Thomasson, Louise


    and define management pathways for fetuses with an abnormal skull shape. Methods: Our FMU databases were searched to ascertain all fetuses with an abnormal skull shape. Sonographic findings, diagnosis and outcome were reviewed. Results: Of the 370 cases identified, 31.6% were associated with spinabifida......Background: Abnormal head shape is an uncommon finding on prenatal ultrasound, often associated with breech presentation, spinabifida, aneuploidy or secondary to oligohydramnios or fetal position. Other aetiologies are rarer and may be more difficult to define. Objective: To determine the aetiology...... incidence of genetic syndromes, in the absence of a clear diagnosis, referral to a tertiary centre and genetic input is advised as detection of subtle sonographic features may aid diagnosis, allowing for targeted molecular analysis. An algorithm for management will be proposed....

  12. Molar incisor hypomineralization (MIH): clinical presentation, aetiology and management. (United States)

    Weerheijm, K L


    In this paper, the current knowledge about Molar Incisor Hypomineralization (MIH) is presented. MIH is defined as hypomineralization of systemic origin of one to four permanent first molars frequently associated with affected incisors and these molars are related to major clinical problems in severe cases. At the moment, only limited data are available to describe the magnitude of the phenomenon. The prevalence of MIH in the different studies ranges from 3.6-25% and seems to differ in certain regions and birth cohorts. Several aetiological factors (for example, frequent childhood diseases) are mentioned as the cause of the defect. Children at risk should be monitored very carefully during the period of eruption of their first permanent molars. Treatment planning should consider the long-term prognosis of these teeth.

  13. Aetiology of Oral Cancer in the Sudan

    Directory of Open Access Journals (Sweden)

    Hussain Gadelkarim Ahmed


    Full Text Available Objectives: To review the studied risk factors that linked to aetiology of oral cancer in the Sudan. There have been numerous reports in the increase in the incidence of oral cancer from various parts of the world. A recent trend for a rising incidence of oral cancer, with the absence of the well established risk factors, has raised concern. Although, there are inconsistent data on incidence and demographical factors, studies suggest that the physiologic response to risk factors by men and women vary in different populations.Material and Methods: This review principally examines 33 publications devoted to aetiology of oral cancer in the Sudan, in addition to some risk factors that are commonly practiced in the Sudan.Results: Several studies examining risk factors for oral cancer include tobacco use (Smoked and Smokeless, alcohol consumption, occupational risk, familial risk, immune deficits, virus infection and genetic factors.Conclusions: Toombak use and infection with high risk Human Papilloma Virus (HPV were extensively investigated and linked to the aetiology of oral cancer in Sudan.

  14. Prevalence and Aetiology of Congenitally Deafblind People in Denmark

    DEFF Research Database (Denmark)

    Dammeyer, Jesper Herup


    were found. Causes of congenital deafblindness were different among adults compared to causes among children. Rubella syndrome (28%, n = 36) and Down syndrome (8%, n = 10) were the largest groups among people above 18 years of age. Among children CHARGE syndrome (16%, n = 13) was the largest group...

  15. Prevalence of viral aetiologies in children with acute respiratory ...

    African Journals Online (AJOL)

    ; 6.4%), influenza (20; 5.2%), respiratory syncytial virus (19; 4.9%) and unidentified viruses (86; 22.2%). Majority of the viruses were isolated from patients with LRTI (110; 28.4%) while URTI had 67 (17.3%) isolates. The age cluster 1-12months ...

  16. Phenomenology of neutrino oscillations

    Indian Academy of Sciences (India)

    Abstract. The phenomenology of solar, atmospheric, supernova and laboratory neutrino oscillations is described. Analytical formulae for matter effects are reviewed. The results from oscillations are confronted with neutrinoless double beta decay.

  17. Phenomenology of Baryon Resonances

    Energy Technology Data Exchange (ETDEWEB)

    Doring, Michael [George Washington Univ., Washington, DC (United States); Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Landay, Justin [George Washington Univ., Washington, DC (United States); Mai, Maxim [George Washington Univ., Washington, DC (United States); Molina, Raquel [Univ. of Sao Paulo (Brazil); Ronchen, Deborah [Univ. of Bonn (Germany)


    Results for light baryon spectroscopy by different collaborations and the state of the art in the subfield is reviewed. Highlights contain common efforts of different phenomenology groups and the impact of recent high-precision data from ELSA, JLab, MAMI, and other facilities. Questions will be addressed, on one side, of how to proceed to reach conclusive answers in baryon spectroscopy, and, on the other side, how phenomenology can be connected to theory in a meaningful way.

  18. Prevalence

    Directory of Open Access Journals (Sweden)

    Mohammed Al-Darwish


    Conclusion: Results indicated that dental caries prevalence among school children in Qatar has reached critical levels, and is influenced by socio-demographic factors. The mean decayed, missing, and filled teeth values obtained in this study were the second highest detected in the Eastern Mediterranean region.

  19. Prevalence

    Directory of Open Access Journals (Sweden)

    Jeanesse Scerri


    Full Text Available Methicillin-resistant Staphylococcus aureus (MRSA is a major nosocomial pathogen worldwide. Malta is one of the countries with the highest MRSA prevalence in Europe, as identified from hospital blood cultures [1]. However, community prevalence of MRSA has never previously been investigated. This study aimed at establishing the prevalence of community MRSA nasal colonization in Maltese individuals and identifying the clonal characteristics of the detected isolates. Nasal swabs were collected from 329 healthy individuals who were also asked to complete a brief questionnaire about risk factors commonly associated with MRSA carriage and infection. The swabs were transported and enriched in a nutrient broth supplemented with NaCl. The presence of MRSA was then determined by culturing on MRSA Select chromogenic agar and then confirming by several assays, including catalase, coagulase and PBP2a agglutination tests. The isolates were assayed for antibiotic susceptibilities and typed by microarray analysis to determine the clonal characteristics of each strain. The prevalence of MRSA nasal colonization in the healthy Maltese population was found to be 8.81% (95% confidence interval [CI], 5.75–11.87%, much higher than that found in other studies carried out in several countries. No statistical association was found between MRSA carriage and demographics or risk factors; however, this was hindered by the small sample size. Almost all the isolates were fusidic-acid resistant. The majority were found to belong to a local endemic clone (CC5 which seems to be replacing the previously prevalent European clone UK-EMRSA-15 in the country. A new clone (CC50-MRSA-V was also characterized. The presence of such a significant community reservoir of MRSA increases the burdens already faced by the local healthcare system to control the MRSA epidemic. Colonization of MRSA in otherwise healthy individuals may represent a risk for endogenous infection and transmission to

  20. Learning Phenomenology with Heidegger: Experiencing the Phenomenological "Starting Point" as the Beginning of Phenomenological Research (United States)

    Quay, John


    Phenomenology has been with us for many years, and yet grasping phenomenology remains a difficult task. Heidegger, too, experienced this difficulty and devoted much of his teaching to the challenge of working phenomenologically. This article draws on aspects of Heidegger's commentary in progressing the teaching and learning of phenomenology,…

  1. Prospective study of autism phenomenology and the behavioural phenotype of Phelan-McDermid syndrome: comparison to fragile X syndrome, Down syndrome and idiopathic autism spectrum disorder. (United States)

    Richards, Caroline; Powis, Laurie; Moss, Jo; Stinton, Christopher; Nelson, Lisa; Oliver, Christopher


    The limited behavioural phenotype literature on Phelan-McDermid syndrome (PMS) indicates atypically high levels of activity, impulsivity and autism spectrum disorder (ASD) behaviours. Divergent profiles of ASD in PMS are also reported, with some studies demonstrating similarities to idiopathic ASD and others indicating an uneven profile of social and communication impairments and repetitive behaviours. An evaluation of the behavioural phenotype of PMS and the prevalence and phenomenology of ASD is warranted, particularly given the causal involvement of the SHANK3 gene in the aetiology of PMS. Carers of individuals with PMS (N = 30; mean age = 10.55, SD = 7.08) completed questionnaires relating to impulsivity, overactivity, mood, interest and pleasure, repetitive behaviour and ASD phenomenology. These data were compared to data from matched samples of individuals with fragile X and Down syndromes and idiopathic ASD. In order to evaluate the profile of ASD phenomenology in PMS, two comparisons were made: first, including the total sample with PMS, and second, including only those who met the threshold indicative of autism on an ASD screening measure. The results revealed lower mood in individuals with PMS, but no differences in impulsivity and overactivity. Compulsive and routine-driven repetitive behaviours were less common in the total sample with PMS; however, motor-based stereotyped behaviours were more common. ASD phenomenology was highly prevalent, with 87% of the sample meeting the cutoff score for ASD and 57% meeting the cutoff for autism. The profile of ASD phenomenology in the total sample with PMS differed from those with idiopathic ASD across impairments in communication and social interaction and repetitive behaviour. However, the profile of those who met the threshold for autism was commensurate to those with idiopathic ASD. ASD phenomenology is common within PMS. Whilst the total sample may display an atypical profile of ASD behaviour, the profile

  2. Understanding the aetiology and resolution of chronic otitis media from animal and human studies


    Bhutta, Mahmood F; Thornton, Ruth B; Kirkham, Lea-Ann S; Kerschner, Joseph E; Cheeseman, Michael T


    ABSTRACT Inflammation of the middle ear, known clinically as chronic otitis media, presents in different forms, such as chronic otitis media with effusion (COME; glue ear) and chronic suppurative otitis media (CSOM). These are highly prevalent diseases, especially in childhood, and lead to significant morbidity worldwide. However, much remains unclear about this disease, including its aetiology, initiation and perpetuation, and the relative roles of mucosal and leukocyte biology, pathogens, a...

  3. Anterior open bite: aetiology and management. (United States)

    Sandler, Paul Jonathan; Madahar, Arun K; Murray, Alison


    Anterior open bite has a multi-factorial aetiology comprising: genetically inherited skeletal pattern, soft tissue effect and digit-sucking habits. To formulate an appropriate treatment plan, accurate diagnosis is essential. Simple open bites may sometimes resolve completely during the transition from mixed to permanent dentition, if the digit-sucking habit is broken. More significant open bites, however, sometimes extending right back to the terminal molars, rarely resolve spontaneously and will often require complex orthodontic treatment, involving active molar intrusion or even major orthognathic surgery. Unfortunately, surgery has associated risks attached, including pain, swelling, bruising, altered nerve sensation and, occasionally, permanent anaesthesia, as well as involving significant costs, as with any major surgical procedure under general anaesthesia. The introduction of Temporary Anchorage Devices (TADs) has expanded the possibilities of orthodontic treatment, beyond traditional limitations of tooth movement. Molar intrusion can be successfully carried out without the need for major surgical intervention, thus avoiding all the attendant risks and disadvantages. This paper provides an overview of anterior open bite and uses an illustrative case where open bite was successfully treated with a combination of fixed appliance therapy and TADs. Anterior open bite is commonly seen in general practice. A knowledge of the possible aetiological factors and their potential management should be understood by general dental practitioners. The increased popularity of TADS allows a new and less invasive approach to management of these cases.

  4. Elastic scattering phenomenology

    Energy Technology Data Exchange (ETDEWEB)

    Mackintosh, R.S. [The Open University, School of Physical Sciences, Milton Keynes (United Kingdom)


    We argue that, in many situations, fits to elastic scattering data that were historically, and frequently still are, considered ''good'', are not justifiably so describable. Information about the dynamics of nucleon-nucleus and nucleus-nucleus scattering is lost when elastic scattering phenomenology is insufficiently ambitious. It is argued that in many situations, an alternative approach is appropriate for the phenomenology of nuclear elastic scattering of nucleons and other light nuclei. The approach affords an appropriate means of evaluating folding models, one that fully exploits available empirical data. It is particularly applicable for nucleons and other light ions. (orig.)

  5. Cultural values and the prevalence of mental disorders in 25 countries: A secondary data analysis. (United States)

    Heim, Eva; Wegmann, Iris; Maercker, Andreas


    The prevalence of common mental disorders (CMDs, i.e., depression and anxiety) worldwide is substantial, and prevalence rates are higher in high-income than in low- and middle-income countries. This difference might reflect both underlying prevalence rates as well as the measurement model used in cross-national epidemiological studies. Schwartz' cultural values provide a meaningful taxonomy to describe 'culture' and to examine how culture affects both the aetiology and phenomenology of CMDs. The present study examines to what extent Schwartz' cultural values correlate with prevalence rates of CMDs at the country-level. Twenty-five countries were included in this study. Countries were included if data on cultural values and lifetime prevalence rates, from either the World Mental Health Surveys or the Global Burden of Disease Study, were available for at least one CMD. Spearman rank correlations were calculated between prevalence rates and cultural values, controlling for gross national income (GNI) per capita. Affective disorders correlated with cultural values, after controlling for GNI. For anxiety disorders, correlations were lower but still offered meaningful insights. Correlations followed the circular structure of values, meaning that the strength of relationship decreased and increased again when moving around the circle: the strongest positive correlations were found with egalitarianism, and the strongest negative correlations with hierarchy and mastery. The autonomy-embeddedness dimension correlated weakly with the prevalence of CMDs. Diverging prevalence rates between high-income countries and low- and middle-income countries are associated with differences in cultural values. Values might not only relate to the aetiology of mental disorders, but most possibly affect the way in which psychological distress is expressed. As an example, in societies with a strong focus on embeddedness, the fear of stigma might be more pronounced. Cultural values offer a

  6. A Phenomenological Research Design Illustrated


    Thomas Groenewald


    This article distills the core principles of a phenomenological research design and, by means of a specific study, illustrates the phenomenological methodology. After a brief overview of the developments of phenomenology, the research paradigm of the specific study follows. Thereafter the location of the data, the data-gathering the data-storage methods are explained. Unstructured in-depth phenomenological interviews supplemented by memoing, essays by participants, a focus group discussion an...

  7. Psychotherapy And Phenomenology

    African Journals Online (AJOL)


    What happens when two people meet and engage in a meaningful conversation, specifically in psycho- therapy? This question has perennially engaged psychology and psychotherapy since its beginnings. Ian Rory Owen's book entitled Psychotherapy and. Phenomenology: On Freud, Husserl and Heidegger is another ...

  8. Brane vector phenomenology

    International Nuclear Information System (INIS)

    Clark, T.E.; Love, S.T.; Nitta, Muneto; Veldhuis, T. ter; Xiong, C.


    Local oscillations of the brane world are manifested as massive vector fields. Their coupling to the Standard Model can be obtained using the method of nonlinear realizations of the spontaneously broken higher-dimensional space-time symmetries, and to an extent, are model independent. Phenomenological limits on these vector field parameters are obtained using LEP collider data and dark matter constraints

  9. The Phenomenology of Democracy (United States)

    Shaw, Robert


    Human beings originate votes, and democracy constitutes decisions. This is the essence of democracy. A phenomenological analysis of the vote and of the decision reveals for us the inherent strength of democracy and its deficiencies. Alexis de Tocqueville pioneered this form of enquiry into democracy and produced positive results from it.…

  10. Superstring inspired phenomenology

    International Nuclear Information System (INIS)

    Binetruy, P.


    Recent progress in superstring model building is reviewed with an emphasis on the general features of the models obtained. The problems associated with supersymmetry breaking and intermediate gauge symmetry breaking (M W I GUT ) are described. Finally, the phenomenology of these models is summarized, with a discussion of the role that new experimental results could play to help clearing up the above difficulties

  11. Phenomenology of SUSY models

    International Nuclear Information System (INIS)

    Diaz-Cruz, J. Lorenzo


    This article presents a review of the minimal supersymmetric extension of the Standard Model (MSSM), concentrating mainly in the steps needed to derive the lagrangian of the model within the superspace formalism. Some attention is also given to the reduction of parameters that results from incorporating the hypothesis of Grand Unification and low energy Supergravity; the most salient phenomenological consequences are also discussed

  12. Phenomenology of radions

    Indian Academy of Sciences (India)

    done by super Yang–Mills sectors in the bulk and on the hidden brane. Interestingly one can get a viable version of the anomaly mediated symmetry breaking in this ... first particle indicating extra dimensions. 2. Radion couplings. Radion couples to the trace of the stress–energy tensor [7,8]. From the phenomenological.

  13. Supersymmetry and Superstring Phenomenology

    Energy Technology Data Exchange (ETDEWEB)

    Gaillard, Mary K; Gaillard, Mary K.; Zumino, Bruno


    We briefly cover the early history of supersymmetry, describe the relation of SUSY quantum field theories to superstring theories and explain why they are considered a likely tool to describe the phenomenology of high energy particle theory beyond the Standard Model.

  14. Phenomenology, Psychoanalysis, and Behaviorism (United States)

    Brandt, Lewis W.


    The author contends that phenomenology and psychoanalysis have in common that they consider the investigator and the subject as equals as evidenced by the application of their basic principles and of their findings to both investigators and investigatees whom they consider human beings cooperating in a joint search for knowledge. (Author)

  15. Aetiology of Abdominal Injuries in Children:- at Olabisi Onabanjo ...

    African Journals Online (AJOL)

    The occurrence of abdominal injuries in children appear to be on the increase in our environment and; several aetiological factors have been implicated. To outline the aetiological factors responsible for abdominal injuries in children managed at our health institution. A two-year prospective study carried out between ...

  16. Aetiology of Depression: Insights from epidemiological and genetic research

    NARCIS (Netherlands)

    O. Story-Jovanova (Olivera)


    markdownabstractThis thesis includes several population-based studies that explore the aetiology of depression, with a specific interest on biological factors, genetics and epigenetics, and physical health factors for depression. Unravelling the aetiology of depression could potentially answer some

  17. Aetiology and outcome of severe community-acquired pneumonia in ...

    African Journals Online (AJOL)

    Objective. To determine the aetiological agents and outcome of severe community-acquired pneumonia (SCAP) in children admitted to the paediatric intensive care unit (PICU) at Kalafong Hospital, Pretoria. Patients and methods. An audit was done after a protocol was implemented to identify the aetiological agents in ...

  18. The aetiology of otosclerosis: a review of the literature

    NARCIS (Netherlands)

    Menger, D. J.; Tange, R. A.


    During the last century, hundreds of studies have been performed to identify factors that are involved in the aetiology of otosclerosis. These studies include a variety of aetiological factors and, although many theories have been postulated, the process of the development of the disease remains

  19. Phenomenology in Its Original Sense. (United States)

    van Manen, Max


    In this article, I try to think through the question, "What distinguishes phenomenology in its original sense?" My intent is to focus on the project and methodology of phenomenology in a manner that is not overly technical and that may help others to further elaborate on or question the singular features that make phenomenology into a unique qualitative form of inquiry. I pay special attention to the notion of "lived" in the phenomenological term "lived experience" to demonstrate its critical role and significance for understanding phenomenological reflection, meaning, analysis, and insights. I also attend to the kind of experiential material that is needed to focus on a genuine phenomenological question that should guide any specific research project. Heidegger, van den Berg, and Marion provide some poignant exemplars of the use of narrative "examples" in phenomenological explorations of the phenomena of "boredom," "conversation," and "the meaningful look in eye-contact." Only what is given or what gives itself in lived experience (or conscious awareness) are proper phenomenological "data" or "givens," but these givens are not to be confused with data material that can be coded, sorted, abstracted, and accordingly analyzed in some "systematic" manner. The latter approach to experiential research may be appropriate and worthwhile for various types of qualitative inquiry but not for phenomenology in its original sense. Finally, I use the mythical figure of Kairos to show that the famous phenomenological couplet of the epoché-reduction aims for phenomenological insights that require experiential analysis and attentive (but serendipitous) methodical inquiry practices.

  20. The phenomenology of comfort. (United States)

    Morse, J M; Bottorff, J L; Hutchinson, S


    From patient narratives, the phenomenological literature and reflection of patients' autobiographical accounts of illness, nine themes reflecting the phenomenological concept of corporeality were used to identify the ways patients achieve comfort. The themes were: the dis-eased body, the disobedient body, the vulnerable body, the violated body, the resigned body, the enduring body, the betraying body and the betraying (neurotic) mind. The process of achieving comfort is based on the patients' needs to live with illness or injury without being dominated by their bodies. The authors argue that while the role of nursing is to provide comfort to the sick, the goal of total comfort is unattainable in patient care. However, if the goal is to enhance comfort, to ease and to relieve distress, comfort remains central to the role of nursing.

  1. Resonant diphoton phenomenology simplified

    Energy Technology Data Exchange (ETDEWEB)

    Panico, Giuliano [IFAE, Universitat Autònoma de Barcelona,E-08193 Bellaterra, Barcelona (Spain); Vecchi, Luca [SISSA,via Bonomea 265, 34136, Trieste (Italy); Dipartimento di Fisica e Astronomia, Università di Padova and INFN - Sezione di Padova,via Marzolo 8, I-35131 Padova (Italy); Wulzer, Andrea [Dipartimento di Fisica e Astronomia, Università di Padova and INFN - Sezione di Padova,via Marzolo 8, I-35131 Padova (Italy)


    A framework is proposed to describe resonant diphoton phenomenology at hadron colliders in full generality. It can be employed for a comprehensive model-independent interpretation of the experimental data. Within the general framework, few benchmark scenarios are defined as representative of the various phenomenological options and/or of motivated new physics scenarios. Their usage is illustrated by performing a characterization of the 750 GeV excess, based on a recast of available experimental results. We also perform an assessment of which properties of the resonance could be inferred, after discovery, by a careful experimental study of the diphoton distributions. These include the spin J of the new particle and its dominant production mode. Partial information on its CP-parity can also be obtained, but only for J≥2. The complete determination of the resonance CP properties requires studying the pattern of the initial state radiation that accompanies the resonant diphoton production.

  2. DSE hadron phenomenology

    International Nuclear Information System (INIS)

    Hecht, M. B.; Roberts, C. D.; Schmidt, S. M.


    A perspective on the contemporary application of Dyson-Schwinger equations, focusing on some recent phenomenological applications: a description and unification of light-meson observable using a one-parameter model of the effective quark-quark interaction, and studies of leptonic and nonleptonic nucleon form factors. The theory and phenomenological application of Dyson-Schwinger equations (DSEs) have seen something of a renaissance. For example, they have been applied simultaneously to phenomena as apparently unconnected as low-energy ππ scattering, B (r a rrow) D * decays and the equation of state for a quark gluon plasma, and there are renewed attempts to understand the origin of the infrared enhancement necessary in the kernel of the quark DSE (QCD gap equation) to generate dynamical chiral symmetry breaking (DCSB). Also significant is the appreciation that in this approach current algebra's anomalies remain a feature of the global aspects of DCSB

  3. Phenomenology of inflationary models (United States)

    Olyaei, Abbas


    There are many inflationary models compatible with observational data. One can investigate inflationary models by looking at their general features, which are common in most of the models. Here we have investigated some of the single-field models without considering their origin in order to find the phenomenology of them. We have shown how to adjust the simple harmonic oscillator model in order to be in good agreement with observational data.

  4. Enterovesical Fistulae: Aetiology, Imaging, and Management

    Directory of Open Access Journals (Sweden)

    Tomasz Golabek


    Full Text Available Background and Study Objectives. Enterovesical fistula (EVF is a devastating complication of a variety of inflammatory and neoplastic diseases. Radiological imaging plays a vital role in the diagnosis of EVF and is indispensable to gastroenterologists and surgeons for choosing the correct therapeutic option. This paper provides an overview of the diagnosis of enterovesical fistulae. The treatment of fistulae is also briefly discussed. Material and Methods. We performed a literature review by searching the Medline database for articles published from its inception until September 2013 based on clinical relevance. Electronic searches were limited to the keywords: “enterovesical fistula,” “colovesical fistula” (CVF, “pelvic fistula”, and “urinary fistula”. Results. EVF is a rare pathology. Diverticulitis is the commonest aetiology. Over two-thirds of affected patients describe pathognomonic features of pneumaturia, fecaluria, and recurrent urinary tract infections. Computed tomography is the modality of choice for the diagnosis of enterovesical fistulae as not only does it detect a fistula, but it also provides information about the surrounding anatomical structures. Conclusions. In the vast majority of cases, this condition is diagnosed because of unremitting urinary symptoms after gastroenterologist follow-up procedures for a diverticulitis or bowel inflammatory disease. Computed tomography is the most sensitive test for enterovesical fistula.

  5. Chronic fatigue syndrome: aetiology, diagnosis and treatment

    Directory of Open Access Journals (Sweden)

    Palacín Delgado Cecilia


    Full Text Available Abstract Chronic fatigue syndrome is characterised by intense fatigue, with duration of over six months and associated to other related symptoms. The latter include asthenia and easily induced tiredness that is not recovered after a night's sleep. The fatigue becomes so severe that it forces a 50% reduction in daily activities. Given its unknown aetiology, different hypotheses have been considered to explain the origin of the condition (from immunological disorders to the presence of post-traumatic oxidative stress, although there are no conclusive diagnostic tests. Diagnosis is established through the exclusion of other diseases causing fatigue. This syndrome is rare in childhood and adolescence, although the fatigue symptom per se is quite common in paediatric patients. Currently, no curative treatment exists for patients with chronic fatigue syndrome. The therapeutic approach to this syndrome requires a combination of different therapeutic modalities. The specific characteristics of the symptomatology of patients with chronic fatigue require a rapid adaptation of the educational, healthcare and social systems to prevent the problems derived from current systems. Such patients require multidisciplinary management due to the multiple and different issues affecting them. This document was realized by one of the Interdisciplinary Work Groups from the Institute for Rare Diseases, and its aim is to point out the main social and care needs for people affected with Chronic Fatigue Syndrome. For this, it includes not only the view of representatives for different scientific societies, but also the patient associations view, because they know the true history of their social and sanitary needs. In an interdisciplinary approach, this work also reviews the principal scientific, medical, socio-sanitary and psychological aspects of Chronic Fatigue Syndrome.

  6. Aetiology of shigellosis in northern Pakistan. (United States)

    Ahmed, Khalil; Shakoori, Farah R; Shakoori, A R


    People of northern Pakistan face health hazards because of poor sanitation practices. Bacterial gastrointestinal infections are very common, and sometimes outbreaks occur. The present study was aimed at evaluating and analyzing infestation of Shigella spp. in patients with suspected gastroenteritis and ascertaining the status of antibiotic therapy. Five hundred and eighty-five faecal samples of patients with suspected gastroenteritis, referred to the District Headquarter Hospital Gilgit, were investigated for common enteropathogenic bacteria from July 1997 to September 1999. Seventy-seven (13.2%) of the faecal specimens were infected with different strains of Shigella spp., 61% of which were Shigella dysenteriae, 15.6% were S. flexneri, and 23.4% were Shigella sp. All Shigella strains were sensitive to ceftriaxone, cefotaxime, ciprofloxacin, and enoxacin. Sixty-one percent of the strains were resistant to both ampicillin and chloramphenicol, and 3.9% to ampicillin and nalidixic acid, while 10.4% were resistant to ampicillin alone and 14.3% to chloramphenicol only. Only 10.4% of the strains were sensitive to all the antibiotics tested. Sixty strains of Shigella spp. were processed for isolation of plasmids, and 58 (97%) of these antibiotic-resistant bacteria harboured at least one plasmid. The number of plasmids varied from 1 to 9. Escherichia coli C600 were transformed with the isolated plasmids. Transformants, containing 23-kb plasmid, resisted growth in media containing antibiotics, thereby indicating that antibiotic resistance is plasmid-borne. Based on the findings of the study, it is concluded that the infestation of Shigella spp. is high in northern Pakistan, the aetiological agents are highly resistant to chloramphenicol and ampicillin, and the antibiotic resistance is mediated by the 23-kb plasmid.

  7. Neutrinos: Theory and Phenomenology

    Energy Technology Data Exchange (ETDEWEB)

    Parke, Stephen


    The theory and phenomenology of neutrinos will be addressed, especially that relating to the observation of neutrino flavor transformations. The current status and implications for future experiments will be discussed with special emphasis on the experiments that will determine the neutrino mass ordering, the dominant flavor content of the neutrino mass eigenstate with the smallest electron neutrino content and the size of CP violation in the neutrino sector. Beyond the neutrino Standard Model, the evidence for and a possible definitive experiment to confirm or refute the existence of light sterile neutrinos will be briefly discussed.

  8. Phenomenology and Mathematics

    CERN Document Server

    Hartimo, Mirja


    During Edmund Husserl,s lifetime, modern logic and mathematics rapidly developed toward their current outlook and Husserl,s writings can be fruitfully compared and contrasted with both 19th century figures (Boole, Schroder, Weierstrass) as well as the 20th century characters (Heyting, Zermelo, Godel). Besides the more historical studies, the internal ones on Husserl alone and the external ones attempting to clarify his role in the more general context of the developing mathematics and logic, Husserl,s phenomenology offers also a systematically rich but little researched area of investigation.

  9. Scanning the phenomenological MSSM

    CERN Document Server

    Wuerzinger, Jonas


    A framework to perform scans in the 19-dimensional phenomenological MSSM is developed and used to re-evaluate the ATLAS experiments' sensitivity to R-parity-conserving supersymmetry with LHC Run 2 data ($\\sqrt{s}=13$ TeV), using results from 14 separate ATLAS searches. We perform a $\\tilde{t}_1$ dedicated scan, only considering models with $m_{\\tilde{t}_1}<1$ TeV, while allowing both a neutralino ($\\tilde{\\chi}_1^0$) and a sneutrino ($\\tilde{\

  10. Review of the Aetiology and Complications of Primary Postpartum ...

    African Journals Online (AJOL)

    Review of the Aetiology and Complications of Primary Postpartum Haemorrhage following vaginal delivery at University of Calabar Teaching Hospital (UCTH), Calabar, Nigeria: A 5-year Review. CI Emechebe, CO Njoku, AN Njoku, JT Ukaga, EM Eyong ...

  11. Aetiology of acute meningoencephalitis in Cambodian children, 2010-2013

    NARCIS (Netherlands)

    Horwood, Paul F.; Duong, Veasna; Laurent, Denis; Mey, Channa; Sothy, Heng; Santy, Ky; Richner, Beat; Heng, Seiha; Hem, Sopheak; Cheval, Justine; Gorman, Christopher; Dussart, Philippe; de Jong, Menno D.; Kerleguer, Alexandra; Guillard, Bertrand; Murgue, Bernadette; Lecuit, Marc; de Lamballerie, Xavier; Farrar, Jeremy J.; Tarantola, Arnaud; Eloit, Marc; Buchy, Philippe


    Acute meningoencephalitis (AME) is associated with considerable morbidity and mortality in children in developing countries. Clinical specimens were collected from children presenting with AME at two Cambodian paediatric hospitals to determine the major aetiologies associated with AME in the

  12. Extrahepatic portal vein thrombosis : aetiology and determinants of survival

    NARCIS (Netherlands)

    Janssen, HLA; Haagsma, EB; van Uum, SHM; van Nieuwkerk, CMJ; Adang, RP; Chamuleau, RAFM; van Hattum, J; Vleggaar, FP; Hansen, BE; Rosendaal, FR; van Hoek, B


    Background-Malignancy, hypercoagulability, and conditions leading to decreased portal flow have been reported to contribute to the aetiology of extrahepatic portal vein thrombosis (EPVT). Mortality of patients with, EPVT may be associated with these concurrent medical conditions or with

  13. Extrahepatic portal vein thrombosis: aetiology and determinants of survival

    NARCIS (Netherlands)

    H.L.A. Janssen (Harry); B.E. Hansen (Bettina); B. van Hoek (Bart); F.R. Rosendaal (Frits); E.B. Haagsma (Els); S.H. van Uum; C.M. van Nieuwkerk; R.P.R. Adang (Rob); R.A. Chamuleau; J. van Hattum (Jan); F.P. Vleggaar (Frank); A.D. Wijnhoud (Annemarie)


    textabstractBACKGROUND: Malignancy, hypercoagulability, and conditions leading to decreased portal flow have been reported to contribute to the aetiology of extrahepatic portal vein thrombosis (EPVT). Mortality of patients with EPVT may be associated with these concurrent medical

  14. Phenomenological three center model

    CERN Document Server

    Poenaru, D N; Gherghescu, R A; Nagame, Y; Hamilton, J H; Ramayya, A V


    Experimental results on ternary fission of sup 2 sup 5 sup 2 Cf suggest the existence of a short-lived quasi-molecular state. We present a three-center phenomenological model able to explain such a state by producing a new minimum in the deformation energy at a separation distance very close to the touching point. The shape parametrization chosen by us allows to describe the essential geometry of the systems in terms of one independent coordinate, namely, the distance between the heavy fragment centers. The shell correction (also treated phenomenologically) only produces quantitative effects; qualitatively it is not essential for the new minimum. Half-lives of some quasi-molecular states which could be formed in sup 1 sup 0 B accompanied fission of sup 2 sup 3 sup 6 U, sup 2 sup 3 sup 6 Pu, sup 2 sup 4 sup 6 Cm, sup 2 sup 5 sup 2 Cf, sup 2 sup 5 sup 2 sup , sup 2 sup 5 sup 6 Fm, sup 2 sup 5 sup 6 sup , sup 2 sup 6 sup 0 No, and sup 2 sup 6 sup 2 Rf are roughly estimated. (authors)

  15. Acute pancreatitis: Demographics, aetiological factors and outcomes ...

    African Journals Online (AJOL)

    Although acute pancreatitis is a common reason for emergency hospital admissions,1 there is a paucity of information about the disease in a South African context2,3 and to what extent disease severity and outcomes compare with published literature on the subject. We prospectively investigated the hospital prevalence,.

  16. Sociodemographic Characteristics and Aetiological Factors of ...

    African Journals Online (AJOL)

    The prevalence of infective vaginal discharge was found to decrease with increasing age, parity and Western education, and increased among patients who had Human immunodeficiency virus (HIV) infection and diabetes mellitus in pregnancy. Conclusion: We recommend close surveillance among high risk patients, and ...


    African Journals Online (AJOL)

    Consideration of the distribution showed that Escherichia coli was more prevalent in children aged between 3 to 5 years (57%) and was the most encountered of the organisms isolated (present in 77.8% of all samples) while Shigella spp was found in 16.3% of samples, Vibrio cholerae 0.7% and other coliforms 5.2%.

  18. Postmodernism, phenomenology and afriphenomenology | Francis ...

    African Journals Online (AJOL)

    In this paper, I aimed to study the relationship between postmodernism and phenomenology. In the study, I established that postmodernism and phenomenology bear similar ontological marking, which base their concepts and methodologies on an individualistic framework. On the basis of such ontological framework, ...

  19. Phenomenology of atmospheric neutrinos

    Directory of Open Access Journals (Sweden)

    Fedynitch Anatoli


    Full Text Available The detection of astrophysical neutrinos, certainly a break-through result, introduced new experimental challenges and fundamental questions about acceleration mechanisms of cosmic rays. On one hand IceCube succeeded in finding an unambiguous proof for the existence of a diffuse astrophysical neutrino flux, on the other hand the precise determination of its spectral index and normalization requires a better knowledge about the atmospheric background at hundreds of TeV and PeV energies. Atmospheric neutrinos in this energy range originate mostly from decays of heavy-flavor mesons, which production in the phase space relevant for prompt leptons is uncertain. Current accelerator-based experiments are limited by detector acceptance and not so much by the collision energy. This paper recaps phenomenological aspects of atmospheric leptons and calculation methods, linking recent progress in flux predictions with particle physics at colliders, in particular the Large Hadron Collider.

  20. The problem of psychopathology and phenomenology. What is viable and not viable in phenomenological psychiatry. (United States)

    Ramos-Gorostiza, Pablo; Adán-Manes, Jaime


    The epistemological underpinnings of psychiatric theory and practice have always been unstable. This reflects the essential contradiction existing between the task (the description and individuation of speech and behavior as psychopathological symptoms) and tools (semiotics). As a result of this contradiction, the history of psychiatry is one of permanent crisis in which there are moments of temporary stability as approaches that aim at organizing this mismatch between tasks and tools gain prevalence. However, these approaches can only offer a false sense of unity, consistency and progress. In this sense, a narrow perspective on a particular period may lead us to believe that psychiatry is just another medical specialty with its own specific theoretical framework like others. However, any such perspective overlooks the coexistence of different schools, disagreements, contradictions, global alternatives, etc. For a certain period of time, phenomenology was assumed to be as the solution for psychiatry’s internal contradiction. As we see it, phenomenology was only partially understood. Despite the great influence it exerted upon psychiatry worldwide, it finally fell into disuse as a mere empiricism. Husserl’s phenomenology was more thoroughly understood and better assimilated by other psychiatrists, and its influence has persisted to the present day. If we view phenomenology in its proper (Husserlian) sense, it is possible to understand psychopathology as a means of creating intelligibility and clarifying the uniqueness of psychiatry. On the other hand, if phenomenology is understood as a representational theory, it will eventually lead to an unavoidable relapse into psychologism, which has been the main path of psychiatry until now.

  1. Aetiology of thrombosed external haemorrhoids: a questionnaire study

    Directory of Open Access Journals (Sweden)

    Rohde Henning


    Full Text Available Abstract Background It is important to better understand the aetiology of thrombosed external haemorrhoids (TEH because recurrence rates are high, prophylaxis is unknown, and optimal therapy is highly debated. Findings We conducted a questionnaire study of individuals with and without TEH. Aetiology was studied by comparison of answers to a questionnaire given to individuals with and without TEH concerning demography, history, and published aetiologic hypotheses. Participants were evaluated consecutively at our institution from March 2004 through August 2005. One hundred forty-eight individuals were enrolled, including 72 patients with TEH and 76 individuals without TEH but with alternative diagnoses, such as a screening colonoscopy or colonic polyps. Out of 38 possible aetiologic factors evaluated, 20 showed no significant bivariate correlation to TEH and were no longer traced, and 16 factors showed a significant bivariate relationship to TEH. By multivariate analysis, six independent variables were found to predict TEH correctly in 79.1% of cases: age of 46 years or younger, use of excessive physical effort, and use of dry toilet paper combined with wet cleaning methods after defaecation were associated with a significantly higher risk of developing TEH; use of bathtub, use of the shower, and genital cleaning before sleep at least once a week were associated with a significantly lower risk of developing TEH. Conclusion Six hypotheses on the causes of TEH have a high probability of being correct and should be considered in future studies on aetiology, prophylaxis, and therapy of TEH.

  2. The incidence and aetiology of acute pancreatitis across Europe. (United States)

    Roberts, Stephen E; Morrison-Rees, Sian; John, Ann; Williams, John G; Brown, Tim H; Samuel, David G

    Acute pancreatitis is increasingly one of the most important acute gastrointestinal conditions throughout much of the world, although incidence and aetiology varies across countries and regions. This study investigated regional and national patterns in the incidence and aetiology of acute pancreatitis, demographic patterns in incidence and trends over time in incidence across Europe. A structured review of acute pancreatitis incidence and aetiology from studies of hospitalised patient case series, cohort studies or other population based studies from 1989 to 2015 and a review of trends in incidence from 1970 to 2015 across all 51 European states. The incidence of acute pancreatitis was reported from 17 countries across Europe and ranged from 4.6 to 100 per 100 000 population. Incidence was usually highest in eastern or northern Europe, although reported rates often varied according to case ascertainment criteria. Of 20 studies that reported on trends in incidence, all but three show percentage increases over time (overall median increase = 3.4% per annum; range = -0.4%-73%). The highest ratios of gallstone to alcohol aetiologies were identified in southern Europe (Greece, Turkey, Italy and Croatia) with lowest ratios mainly in eastern Europe (Latvia, Finland, Romania, Hungary, Russia and Lithuania). The incidence of acute pancreatitis varies across Europe. Gallstone is the dominant aetiology in southern Europe and alcohol in eastern Europe with intermediate ratios in northern and western Europe. Acute pancreatitis continues to increase throughout most of Europe. Copyright © 2017. Published by Elsevier B.V.

  3. Incidence, aetiology and prevention of musculoskeletal injuries in volleyball: A systematic review of the literature. (United States)

    Kilic, O; Maas, M; Verhagen, E; Zwerver, J; Gouttebarge, V


    Currently, there is no overview of the incidence and (volleyball-specific) risk factors of musculoskeletal injuries among volleyball players, nor any insight into the effect of preventive measures on the incidence of injuries in volleyball. This study aimed to review systematically the scientific evidence on the incidence, prevalence, aetiology and preventive measures of volleyball injuries. To this end, a highly sensitive search strategy was built based on two groups of keywords (and their synonyms). Two electronic databases were searched, namely Medline (biomedical literature) via Pubmed, and SPORTDiscus (sports and sports medicine literature) via EBSCOhost. The results showed that ankle, knee and shoulder injuries are the most common injuries sustained while playing volleyball. Results are presented separately for acute and overuse injuries, as well as for contact and non-contact injuries. Measures to prevent musculoskeletal injuries, anterior knee injuries and ankle injuries were identified in the scientific literature. These preventive measures were found to have a significant effect on decreasing the occurrence of volleyball injuries (for instance on ankle injuries with a reduction from 0.9 to 0.5 injuries per 1000 player hours). Our systematic review showed that musculoskeletal injuries are common among volleyball players, while effective preventive measures remain scarce. Further epidemiological studies should focus on other specific injuries besides knee and ankle injuries, and should also report their prevalence and not only the incidence. Additionally, high-quality studies on the aetiology and prevention of shoulder injuries are lacking and should be a focus of future studies.

  4. Perspectives on string phenomenology

    CERN Document Server

    Kane, Gordon; Kumar, Piyush


    The remarkable recent discovery of the Higgs boson at the CERN Large Hadron Collider completed the Standard Model of particle physics and has paved the way for understanding the physics which may lie beyond it. String/M theory has emerged as a broad framework for describing a plethora of diverse physical systems, which includes condensed matter systems, gravitational systems as well as elementary particle physics interactions. If string/M theory is to be considered as a candidate theory of Nature, it must contain an effectively four-dimensional universe among its solutions that is indistinguishable from our own. In these solutions, the extra dimensions of string/M Theory are “compactified” on tiny scales which are often comparable to the Planck length. String phenomenology is the branch of string/M theory that studies such solutions, relates their properties to data, and aims to answer many of the outstanding questions of particle physics beyond the Standard Model. This book contains perspectives on stri...

  5. [Phenomenology of dreams]. (United States)

    Pringuey, Dominique


    A phenomenology of dreams searches for meaning, with the aim not only of explaining but also of understanding the experience. What and who is it for? And what about the nearly forgotten dream among the moderns, the banal returning to the nightmare, sleepiness, or dreamlike reverie. Nostalgia for the dream, where we saw a very early state of light, not a ordinaire qu duel. Regret for the dreamlike splendor exceeded by the modeling power of modern aesthetics--film and the explosion of virtual imaging technologies. Disappointment at the discovery of a cognitive permanence throughout sleep and a unique fit with the real upon awaking? An excess of methodological rigor where we validate the logic of the dream, correlating the clinical improvement in psychotherapy and the ability to interpret one's own dreams. The dangerous psychological access when the dream primarily is mine, viewed as a veiled expression of an unspoken desire, or when the dream reveals to me, in an existential conception of man, through time and space, my daily life, my freedom beyond my needs. Might its ultimate sense also mean its abolition? From the story of a famous forgotten dream, based on unexpected scientific data emerges the question: do we dream to forget? The main thing would not be consciousness but confidence, when " the sleeping man, his regard extinguished, dead to himself seizes the light in the night " (Heraclitus).

  6. Phenomenological consequences of supersymmetry

    International Nuclear Information System (INIS)

    Hinchliffe, I.; Littenberg, L.


    This report deals with the phenomenological consequences of supersymmetric theories, and with the implications of such theories for future high energy machines. It is concerned only with high energy predictions of supersymmetry; low energy consequences (for example in the K/sub o/anti K/sub o/ system) are discussed in the context of future experiments by another group, and will be mentioned briefly only in the context of constraining existing models. However a brief section is included on the implication for proton decay, although detailed experimental questions are not discussed. The report is organized as follows. Section I consists of a brief review of supersymmetry and the salient features of existing supersymmetric models; this section can be ignored by those familiar with such models since it contains nothing new. Section 2 deals with the consequences for nucleon decay of SUSY. The remaining sections then discuss the physics possibilities of various machines; e anti e in Section 3, ep in Section 4, pp (or anti pp) colliders in Section 5 and fixed target hadron machines in Section 6

  7. Distinct Patterns and Aetiology of Chromonychia

    Directory of Open Access Journals (Sweden)

    Soo Hyeon Bae


    Full Text Available Abnormal colouring of the nails may be a sign of underlying systemic or local disorders. This study investigated the prevalence and causes of chromonychia as a whole, as well as of each subtype. Among 163 patients with chromonychia, trauma was the pathogenesis in up to 20.9% (34/163 of cases. The most common subtype was melanonychia (54.0%; 88/163, followed by leukonychia (23.9%, red (8.6%, green (6.7%, yellow (4.9% and blue (1.8% nails. Nail matrix naevus (33.3%; 29/88 was the most common cause of melanonychia, while skin diseases (41.0%; 16/39, such as psoriasis (75%, 12/16 and alopecia areata (18.8%; 3/16, in addition to systemic diseases (33.3%; 13/39 including anaemia (38.5%, 5/13 and chronic renal failure (15.4%; 2/13 were the dominant causes of leukonychia. As chromonychia may be the first or only sign of an underlying disorder, it should alert physicians and patients to the need for a prompt and thorough evaluation.

  8. Lack of evidence for a role of islet autoimmunity in the aetiology of canine diabetes mellitus. (United States)

    Ahlgren, Kerstin M; Fall, Tove; Landegren, Nils; Grimelius, Lars; von Euler, Henrik; Sundberg, Katarina; Lindblad-Toh, Kerstin; Lobell, Anna; Hedhammar, Åke; Andersson, Göran; Hansson-Hamlin, Helene; Lernmark, Åke; Kämpe, Olle


    Diabetes mellitus is one of the most common endocrine disorders in dogs and is commonly proposed to be of autoimmune origin. Although the clinical presentation of human type 1 diabetes (T1D) and canine diabetes are similar, the aetiologies may differ. The aim of this study was to investigate if autoimmune aetiology resembling human T1D is as prevalent in dogs as previously reported. Sera from 121 diabetic dogs representing 40 different breeds were tested for islet cell antibodies (ICA) and GAD65 autoantibodies (GADA) and compared with sera from 133 healthy dogs. ICA was detected by indirect immunofluorescence using both canine and human frozen sections. GADA was detected by in vitro transcription and translation (ITT) of human and canine GAD65, followed by immune precipitation. Sections of pancreata from five diabetic dogs and two control dogs were examined histopathologically including immunostaining for insulin, glucagon, somatostatin and pancreas polypeptide. None of the canine sera analysed tested positive for ICA on sections of frozen canine or human ICA pancreas. However, serum from one diabetic dog was weakly positive in the canine GADA assay and serum from one healthy dog was weakly positive in the human GADA assay. Histopathology showed marked degenerative changes in endocrine islets, including vacuolisation and variable loss of immune-staining for insulin. No sign of inflammation was noted. Contrary to previous observations, based on results from tests for humoral autoreactivity towards islet proteins using four different assays, and histopathological examinations, we do not find any support for an islet autoimmune aetiology in canine diabetes mellitus.

  9. Lack of evidence for a role of islet autoimmunity in the aetiology of canine diabetes mellitus.

    Directory of Open Access Journals (Sweden)

    Kerstin M Ahlgren

    Full Text Available AIMS/HYPOTHESIS: Diabetes mellitus is one of the most common endocrine disorders in dogs and is commonly proposed to be of autoimmune origin. Although the clinical presentation of human type 1 diabetes (T1D and canine diabetes are similar, the aetiologies may differ. The aim of this study was to investigate if autoimmune aetiology resembling human T1D is as prevalent in dogs as previously reported. METHODS: Sera from 121 diabetic dogs representing 40 different breeds were tested for islet cell antibodies (ICA and GAD65 autoantibodies (GADA and compared with sera from 133 healthy dogs. ICA was detected by indirect immunofluorescence using both canine and human frozen sections. GADA was detected by in vitro transcription and translation (ITT of human and canine GAD65, followed by immune precipitation. Sections of pancreata from five diabetic dogs and two control dogs were examined histopathologically including immunostaining for insulin, glucagon, somatostatin and pancreas polypeptide. RESULTS: None of the canine sera analysed tested positive for ICA on sections of frozen canine or human ICA pancreas. However, serum from one diabetic dog was weakly positive in the canine GADA assay and serum from one healthy dog was weakly positive in the human GADA assay. Histopathology showed marked degenerative changes in endocrine islets, including vacuolisation and variable loss of immune-staining for insulin. No sign of inflammation was noted. CONCLUSIONS/INTERPRETATIONS: Contrary to previous observations, based on results from tests for humoral autoreactivity towards islet proteins using four different assays, and histopathological examinations, we do not find any support for an islet autoimmune aetiology in canine diabetes mellitus.

  10. Aetiological Patterns and Management Outcome of Paediatric Head ...

    African Journals Online (AJOL)

    Trauma is themost common cause of paediatric deaths. In75% of paediatric trauma deaths, head injury is responsible, and most are from falls. Recent reports from Nigeria, however, appear to indicate a predominance of road traffic accidents, instead of falls. To evaluate the aetiology of paediatric head trauma, management ...

  11. The aetiology of idiopathic scoliosis : biomechanical and neuromuscular factors

    NARCIS (Netherlands)

    Veldhuizen, AG; Webb, PJ

    The aetiology of adolescent idiopathic scoliosis (AIS) remains an enigma. In the literature there are two opinions: one believes a deviating growth pattern is responsible for the condition - patients with AIS lend to be growing faster/be taller - while the other opinion assumes that the growth

  12. Ignored Aetiologic Factors of Growth Faltering/Stunting In Sierra ...

    African Journals Online (AJOL)

    Until recently, the role of aflatoxins as a causative agent of stunting was never explored. Recent studies carried out in Benin, Togo and The Gambia have implicated aflatoxin in the aetiology of stunting/growth faltering in children. Studies carried out in the Southern province (Bo and Njala) have demonstrated that children not ...

  13. Aetiology, pattern and management of oral and maxillofacial injuries ...

    African Journals Online (AJOL)

    Objective: To establish the aetiology, pattern and methods of management of oral and Maxillofacial injuries (OMFIs) seen at the Oral and Jaw injuries unit of Mulago National Referral Hospital (MNRH) Kampala, Uganda, over a ten year period. Design: A descriptive retrospective study. Setting: Oral and jaw injury unit of ...


    African Journals Online (AJOL)

    Engr E. Egbochukwu

    Abstract. The study investigated the aetiology of Igbo cultural rites with the aim of highlighting the implications for church and community relations as a means of promoting peaceful co-existence. The investigation isolated the following rites namely: “igu afa” (naming ceremony); “igba nnunnu”(shooting of birds); “uche.

  15. “Spoiling the womb”: Definitions, Aetiologies and responses to ...

    African Journals Online (AJOL)

    Spoiling the womb”: Definitions, Aetiologies and responses to infertility in North West Province, Cameroon. ... Now, family planning is promoted nationwide to reduce population growth, and infertility is not addressed by public health policy or services. In contrast to the biomedical definition used by planners, at the local level ...

  16. A study of the aetiology of anaemia in hospitalized newborns ...

    African Journals Online (AJOL)

    Background: Anaemia contributes significantly to neonatal morbidity and mortality. This study describes the aetiology of anemia in ill babies in order to highlight the underlying conditions, proffer preventive measures and sensitize Physicians to improve on the management of anemia in babies. Methods: This was a ...

  17. Extrahepatic portal vein thrombosis: aetiology and determinants of survival

    NARCIS (Netherlands)

    Janssen, H. L.; Wijnhoud, A.; Haagsma, E. B.; van Uum, S. H.; van Nieuwkerk, C. M.; Adang, R. P.; Chamuleau, R. A.; van Hattum, J.; Vleggaar, F. P.; Hansen, B. E.; Rosendaal, F. R.; van Hoek, B.


    Malignancy, hypercoagulability, and conditions leading to decreased portal flow have been reported to contribute to the aetiology of extrahepatic portal vein thrombosis (EPVT). Mortality of patients with EPVT may be associated with these concurrent medical conditions or with manifestations of portal

  18. The aetiology and possible prevention of myocardial infarction ...

    African Journals Online (AJOL)

    The subjects of this study were 250 cases of myocardial infarction treated personally. Despite lack of proof that the relationship is causal there is a clear association with obesity, excessive cigarette smoking, hypertension, emotional stress, hyperuricaemia and in qualified groups hyperlipidaemia. Until the aetiology of ...

  19. Changing pattern of incidence, aetiology and mortality from acute ...

    African Journals Online (AJOL)

    Background: Literature reports from Western countries suggest an increasing incidence of acute pancreatitis (AP) and changing pattern over the past two decades. The aim of this study was to document the incidence, aetiology and mortality from AP over two decades and to examine any emerging trends. Methods: A ...

  20. Aetiology of molar-incisor hypomineralization: a critical review. (United States)

    Crombie, Felicity; Manton, David; Kilpatrick, Nicola


    The objective of this study was to assess the strength of evidence for the aetiology of molar-incisor hypomineralization (MIH), often as approximated by demarcated defects. A systematic search of online medical databases was conducted with assessment of titles, abstracts, and finally full articles for selection purposes. The level and quality of evidence were then assessed for each article according to Australian national guidelines. Of 1123 articles identified by the database search, 53 were selected for review. These covered a variety of potential aetiological factors, some of which were grouped together for convenience. The level of evidence provided by the majority of papers was low and most did not specifically investigate MIH. There was moderate evidence that polychlorinated biphenyl/dioxin exposure is involved in the aetiology of MIH; weak evidence for the role of nutrition, birth and neonatal factors, and acute or chronic childhood illness/treatment; and very weak evidence to implicate fluoride or breastfeeding. There is currently insufficient evidence in the literature to establish aetiological factor/s relevant for MIH. Improvements in study design, as well as standardization of diagnostic and examination protocols, would improve the level and strength of evidence.

  1. aetiology, pattern and management of oral and maxillofacial injuries ...

    African Journals Online (AJOL)


    Nov 1, 2012 ... injuries and public health measures targeting prevention should focus on these areas. INTRODUCTION. In sub-Saharan Africa, ... casualty transport systems and ill-equipped health facilities. The aetiology of Oral and ... chronic traffic jams on major roads in Uganda and for its ability to pass through difficult ...

  2. Occurrence, aetiology and challenges in the management of ...

    African Journals Online (AJOL)

    Introduction: The aim of the study was to investigate the occurrence, the aetiology and the management of congestive heart failure in the cardiac centre of the St. Elizabeth catholic general hospital Shisong in Cameroon. Methods: Between November 2002 and November 2008, a population of 8121 patients was consulted in ...

  3. Aetiology of Proximal Weakness among Adult Sudanese patients ...

    African Journals Online (AJOL)

    Objective: To determine the aetiology of proximal myopathy among adult. Sudanese patients seen in Elshaab Teaching Hospital. Methods: This is a descriptive cross sectional hospital based study conducted in Elshaab Teaching Hospital, during the period from January 2004 September 2005. 100 adult Sudanese patients ...

  4. Fungal Nail Infections: Spectrum of Aetiologic Agents and Pattern of Lesions

    Directory of Open Access Journals (Sweden)

    Anyimson James


    Full Text Available Objective: Worldwide, fungal nail infections have been on the increase, with social, cultural and economic factors contributing to it. Information on the spectrum of fungal nail infection is sparse in Nigeria. This study was carried out to establish the infection rates, aetiology and clinical types of onychomycosis in Calabar. Methods: Subjects were drawn from manicure and pedicure salons, farming settlements, mechanic workshops and dermatology clinic. A structured questionnaire was administered to participants for demographic data. Nail scrapings and clippings were obtained from subjects under standard aseptic procedure. Samples were pulverized and subjected to microscopy and culture. Standard mycological techniques were used to identify and characterize isolates. Results: Out of the 32.7% infection rates in the study, males 33.8%% were more infected than females 32.3% and subjects aged 41-50 years had the highest rate of infections. Candida species were more prevalent 63.6% than dermatophytic moulds 36.4%. Trichophyton rubrum was the most prevalent 18.2% dermatophyte. The distribution of pathogenic isolates on fingernails 45.5% and toenails 42.4% was statistically significant (χ2 =7.2, p= 0.03. Disto-lateral subungual onychomycosis (DLSO 51(50.5% was the most common type of nail lesion but most of the isolates 14(42.4% were recovered from TDO. Conclusion: Onychomycosis affected more adults than adolescents of both sexes in our locality. Candida species are becoming prevalent aetiologic agents of these infections, and their importance should not be overlooked in the management of patients. J Microbiol Infect Dis 2016;6(1: 23-27

  5. Cryptorchidism: classification, prevalence and long-term consequences

    DEFF Research Database (Denmark)

    Virtanen, Helena E; Bjerknes, Robert; Cortes, Dina


    Undescended testis is a common finding in boys, and the majority of cases have no discernible aetiology. There are unexplained geographical differences and temporal trends in its prevalence. Cryptorchidism, especially bilateral, is associated with impaired spermatogenesis and endocrine function...

  6. Role of Gut Microbiota in the Aetiology of Obesity: Proposed Mechanisms and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Muhammad Jaffar Khan


    Full Text Available The aetiology of obesity has been attributed to several factors (environmental, dietary, lifestyle, host, and genetic factors; however none of these fully explain the increase in the prevalence of obesity worldwide. Gut microbiota located at the interface of host and environment in the gut are a new area of research being explored to explain the excess accumulation of energy in obese individuals and may be a potential target for therapeutic manipulation to reduce host energy storage. Several mechanisms have been suggested to explain the role of gut microbiota in the aetiology of obesity such as short chain fatty acid production, stimulation of hormones, chronic low-grade inflammation, lipoprotein and bile acid metabolism, and increased endocannabinoid receptor system tone. However, evidence from animal and human studies clearly indicates controversies in determining the cause or effect relationship between the gut microbiota and obesity. Metagenomics based studies indicate that functionality rather than the composition of gut microbiota may be important. Further mechanistic studies controlling for environmental and epigenetic factors are therefore required to help unravel obesity pathogenesis.

  7. ENDOCRINOLOGY OF PREGNANCY: Gestational diabetes mellitus: definition, aetiological and clinical aspects. (United States)

    Baz, Baz; Riveline, Jean-Pierre; Gautier, Jean-François


    Gestational diabetes (GDM) is defined as a glucose intolerance resulting in hyperglycaemia of variable severity with onset during pregnancy. This review aims to revisit the pathogenesis and aetiology of GDM in order to better understand its clinical presentation and outcomes. During normal pregnancy, insulin sensitivity declines with advancing gestation. These modifications are due to placental factors, progesterone and estrogen. In a physiological situation, a compensatory increase in insulin secretion maintains a normal glucose homeostasis. GDM occurs if pancreatic β-cells are unable to face the increased insulin demand during pregnancy. GDM is most commonly a forerunner of type 2 diabetes (T2D) - the most prevalent form of diabetes. These women share similar characteristics with predisposed subjects to T2D: insulin resistance before and after pregnancy, and carry more T2D risk alleles. Auto-immune and monogenic diabetes are more rare aetiologies of GDM. Adverse pregnancy outcomes of GDM are mainly related to macrosomia caused by fetal hyperinsulinism in response to high glucose levels coming from maternal hyperglycaemia. Screening recommendations and diagnosis criteria of GDM have been recently updated. High risk patients should be screened as early as possible using fasting plasma glucose, and if normal, at 24-28 weeks of gestation using 75 g oral glucose tolerance test. The treatment of GDM is based on education with trained nurses and dieticians, and if necessary insulin therapy. © 2016 European Society of Endocrinology.

  8. Viral pneumonia in adults in sub-Saharan Africa – epidemiology, aetiology, diagnosis and management

    Directory of Open Access Journals (Sweden)

    Antonia Ho


    Full Text Available Community-acquired pneumonia causes substantial morbidity and mortality in sub-Saharan Africa with an estimated 131 million new cases each year. Viruses – such as influenza virus, respiratory syncytial virus and parainfluenza virus – are now recognised as important causes of respiratory disease in older children and adults in the developed world following the emergence of sensitive molecular diagnostic tests, recent severe viral epidemics, and the discovery of novel viruses. Few studies have comprehensively evaluated the viral aetiology of adult pneumonia in Africa, but it is likely to differ from Western settings due to varying seasonality and the high proportion of patients with immunosuppression and co-morbidities. Emerging data suggest a high prevalence of viral pathogens, as well as multiple viral and viral/bacterial infections in African adults with pneumonia. However, the interpretation of positive results from highly sensitive polymerase chain reaction tests can be challenging. Therapeutic and preventative options against viral respiratory infections are currently limited in the African setting. This review summarises the current state of the epidemiology, aetiology, diagnosis and management of viral pneumonia in sub-Saharan Africa.

  9. Role of Gut Microbiota in the Aetiology of Obesity: Proposed Mechanisms and Review of the Literature (United States)

    Gerasimidis, Konstantinos; Edwards, Christine Ann; Shaikh, M. Guftar


    The aetiology of obesity has been attributed to several factors (environmental, dietary, lifestyle, host, and genetic factors); however none of these fully explain the increase in the prevalence of obesity worldwide. Gut microbiota located at the interface of host and environment in the gut are a new area of research being explored to explain the excess accumulation of energy in obese individuals and may be a potential target for therapeutic manipulation to reduce host energy storage. Several mechanisms have been suggested to explain the role of gut microbiota in the aetiology of obesity such as short chain fatty acid production, stimulation of hormones, chronic low-grade inflammation, lipoprotein and bile acid metabolism, and increased endocannabinoid receptor system tone. However, evidence from animal and human studies clearly indicates controversies in determining the cause or effect relationship between the gut microbiota and obesity. Metagenomics based studies indicate that functionality rather than the composition of gut microbiota may be important. Further mechanistic studies controlling for environmental and epigenetic factors are therefore required to help unravel obesity pathogenesis. PMID:27703805

  10. Epidemiology, aetiology and outcomes of acute pancreatitis: A retrospective cohort study. (United States)

    Nesvaderani, Maryam; Eslick, Guy D; Vagg, Daniel; Faraj, Shadi; Cox, Michael R


    Acute pancreatitis is a common acute surgical presentation in Western Society. The causes and pattern of pancreatitis has not been previously documented for Western Sydney. As Western Sydney contains many areas of low socio-economic status with an expected high level of alcohol abuse, it was hypothesised that alcoholic pancreatitis would be more prevalent in this population. The aims of this study were to determine the epidemiology, aetiology and outcomes of acute pancreatitis. A retrospective analysis of patients presenting with acute pancreatitis to four tertiary hospitals over a four-year period was undertaken. 932 patients presented with acute pancreatitis with a median age of 50 years (range 16-95); 470 (50.4%) were female. Almost half had gallstones (40%), 25.6% idiopathic, 22% alcohol induced and 3.9% post ERCP. 69 (7.4%) of patients were admitted to ICU/HDU, with a median length of stay in ICU was 6 days (range 1-106). 85 (11.1%) patients had severe pancreatitis (score ≥ 3). Mortality in this study was 1% (9). The majority of patients with acute pancreatitis in Western Sydney present with mild disease and have a low risk of morbidity or mortality. The ratio of gallstone to alcohol aetiology was 2:1. Idiopathic pancreatitis is responsible for more cases than expected. Crown Copyright © 2015. Published by Elsevier Ltd. All rights reserved.

  11. Reflexividade em saúde: investigação fenomenológica do processo reflexivo prevalente entre os formandos em educação física Reflexivity in health: phenomenological research on the reflective process prevalent among graduates in physical education

    Directory of Open Access Journals (Sweden)

    Karina Tiemi Murata


    Full Text Available O presente trabalho buscou identificar e compreender como se dão os processos reflexivos prevalentes na relação interpessoal constituída na atuação pré-profissional de formandos em um curso na área da educação física. Tendo em vista este objetivo, utilizou-se a fenomenologia como um método capaz de identificar o sentido das coisas dadas à consciência. Optou-se também pela utilização adaptada de um roteiro de supervisão para psicólogos do esporte por abordar amplamente os variados aspectos da experiência relacional em contexto de atendimento. Os resultados apontam para a prevalência do modo de pensamento mecanicista como plano de fundo de uma reflexividade causal e restrita durante a atuação pré-profissional destes formandos. Assim, uma atuação dirigida à reflexibilidade, possibilita uma abertura ao relacionamento interpessoal de maneira a incluir o sujeito a quem a prática se destina como agente do processo, e não como objeto de intervenção. O método fenomenológico pode auxiliar na manutenção e constante aprimoramento deste processo reflexivo, uma vez que permite compreender as dimensões de ordem existencial da atividade física.This study sought to identify and understand how to give the reflective processes prevalent in interpersonal relationships formed in the pre-professional performance of graduates in a in physical education program. Toward this goal, we used phenomenology as a method capable of identifying the meaning of things given to consciousness. The choice was made for the use of a supervision script for sport psychologists because of its approach of widely varied aspects of relational experience in the context to address the widely varied aspects of human experience in context of care. The results indicate the prevalence of a mechanistic way of thinking as the background of a causal and restricted reflexivity during the pre-professional performance of these graduates. Thus, an action directed at

  12. Quantum Gravity and Phenomenological Philosophy (United States)

    Rosen, Steven M.


    The central thesis of this paper is that contemporary theoretical physics is grounded in philosophical presuppositions that make it difficult to effectively address the problems of subject-object interaction and discontinuity inherent to quantum gravity. The core objectivist assumption implicit in relativity theory and quantum mechanics is uncovered and we see that, in string theory, this assumption leads into contradiction. To address this challenge, a new philosophical foundation is proposed based on the phenomenology of Maurice Merleau-Ponty and Martin Heidegger. Then, through the application of qualitative topology and hypernumbers, phenomenological ideas about space, time, and dimension are brought into focus so as to provide specific solutions to the problems of force-field generation and unification. The phenomenological string theory that results speaks to the inconclusiveness of conventional string theory and resolves its core contradiction.

  13. Psychology and phenomenology: a clarification. (United States)

    Kendler, Howard H


    Controversies are rampant in contemporary psychology concerning the appropriate method for observing consciousness and the role inner experience should play in psychological theorizing. These conflicting orientations reflect, in part, methodological differences between natural science and human science interpretations of psychology. Humanistic psychology and philosophical phenomenology both employ a human science approach to psychology that seeks to explain behavior in terms of a person's subjective existence. Maslow's and Heidegger's formulations are both fulfillment theories in that they specify moral values that suggest how life ought to be lived. Natural science methodology rejects the possibility that moral imperatives can be validated, whereas human science methodology allows phenomenological convictions to justify recommendations about a fulfilled life and a good society. The social role of psychology is analyzed within the framework of phenomenological convictions and scientific truth. 2005 APA, all rights reserved

  14. Phenomenology and hermeneutics - poles apart?

    DEFF Research Database (Denmark)

    Keller, Kurt Dauer; Feilberg, Casper

    A key dispute within qualitative methodology is the choice between top-down (deductive) and bottom-up (inductive) research approaches. Abduction, on the other hand, has received little attention, even though it would often seem to be a more promising methodology. The phenomenological tradition...... is marked by a similar dichotomy, whereas hermeneutical phenomenologists argue for the necessity of preunderstanding and theorethical perspectives (van Manen), Husserlian phenomenologists insist on the importance of the epoché together with reduction. The existential phenomenology of Heidegger and Merleau......-Ponty offers a methodological clarification that points to three basic methods of henomenology: description (reduction), interpretation (construction) and ritique (destruction). We recognize that all phenomenological research relates to escription, but we will emphasize the importance of interpretation...

  15. Individualized assessment and phenomenological psychology. (United States)

    Fischer, C T


    Although there is growing openness to tailoring of assessment procedures and reports to the particular client, these efforts typically have been sporadic and incomplete. This article reviews a systematic approach to individualized assessment, one whose practices are referred to as collaborative, contextual, and interventional. Clinical examples of these practices are presented in terms of their grounding in phenomenological psychology. Prior to that, themes such as intentionality, situatedness, dialectics, structuralism, and hermeneutics are introduced briefly. Phenomenological psychology as such is not seen here as necessary for all individualized practices, but it is seen as a critical touchpoint for development of theory and further practices.

  16. The post-discectomy syndrome. Aetiology, diagnosis, treatment, prevention. (United States)

    Ivanic, G M; Pink, T P; Homann, N C; Scheitza, W; Goyal, S


    The post-discectomy syndrome (PDS) is a common diagnosis in patients with problems following a disc operation. The different causes of PDS make the establishment of the correct diagnosis and its corresponding efficient treatment difficult. A general overview published in the bibliographical data covering the entity of PDS is rare. The following paper aims to specify PDS according to its aetiology, diagnosis, treatment and prevention. The diagnosis should be made efficiently, so that the patient can receive prompt adequate therapy.

  17. Diverse genetic aetiologies and clinical outcomes of paediatric hypoparathyroidism. (United States)

    Kim, Ja Hye; Shin, Young-Lim; Yang, Seung; Cheon, Chong Kun; Cho, Ja Hyang; Lee, Beom Hee; Kim, Gu-Hwan; Lee, Jin Ok; Seo, Eul Joo; Choi, Jin-Ho; Yoo, Han-Wook


    Hypoparathyroidism is characterized by hypocalcaemia, hyperphosphataemia, and low or inappropriately normal parathyroid hormone (PTH) levels. Idiopathic or genetic drivers are the predominant causes of hypoparathyroidism in paediatric-age patients. This study investigated the aetiology and clinical course of primary hypoparathyroidism in infancy and childhood. This study included 37 patients (23 males, 14 females) with primary hypoparathyroidism diagnosed prior to 18 years of age. We analysed aetiologies, initial presentation, age at diagnosis, endocrine and radiological findings, and outcomes. The median age at presentation was 1·7 months (range 1 day-17 years), and the mean follow-up duration was 7·0 ± 5·3 years (range 0·5-16·8 years). Our cohort included 22 cases (59·5%) of 22q11·2 microdeletion syndrome. Other aetiologies included hypoparathyroidism-deafness-renal dysplasia syndrome (5/37, 13·5%) and one patient each with autoimmune polyglandular syndrome type 1, Kearns-Sayre syndrome and Kenny-Caffey syndrome. The remaining 7 (18·9%) patients were classified as idiopathic hypoparathyroidism cases. Among the 15 patients who underwent brain imaging, 5 (33·3%) had basal ganglia calcification. Among the 26 patients examined by renal imaging, 5 (19·2%) had either nephrocalcinosis or a renal stone. After 11 months of calcium or calcitriol supplementation, 16 patients (43·2%) discontinued medication. The final PTH levels were significantly higher in patients with transient hypoparathyroidism than those with permanent hypoparathyroidism. Identification of the genetic aetiologies of hypoparathyroidism makes it possible to predict patient outcomes and provide appropriate genetic counselling. Long-term treatment with calcium and calcitriol necessitates monitoring for renal complications. © 2015 John Wiley & Sons Ltd.

  18. Transepidermal water loss in erythrodermic patients of various aetiologies. (United States)

    Mohd Noor, Noorlaily; Hussein, Suraiya H


    Despite its severity not much work has been done to explore the barrier function in patients with erythroderma. This study compares TEWL between skin of healthy subjects and erythrodermic patients of various aetiologies and at different sites. We also assess TEWL between patients with acute and chronic erythroderma. Twenty-five erythrodermic patients and 26 age, race and sex-matched healthy controls were recruited. TEWL measurements were performed at five sites; right cheek, left volar forearm, abdomen, upper back and right calf using Tewameter TM 210. TEWL in erythrodermic patients were significantly higher than healthy individuals at all the sites (P < 0.001). There were significant differences in TEWL between different anatomical sites in controls (P < 0.001) but not in patients. The highest TEWL for the patient and control groups were that of the abdomen and the right cheek respectively. Acute erythrodermic patients (n = 9) seemed to have a higher TEWL than chronic erythrodermic patients (n = 16) although the differences were not statistically significant. There was no significant difference in TEWL among erythrodermic patients of various aetiologies. Erythrodermic skin regardless of aetiology has much higher TEWL compared to normal skin. Differences in TEWL among various anatomical sites observed in normal skin were not seen in erythroderma. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  19. Aetiology of auditory dysfunction in amusia: a systematic review. (United States)

    Casey, Daniel Aj


    Amusia, a music-specific agnosia, is a disorder of pitch interval analysis and pitch direction change recognition which results in a deficit in musical ability. The full range of aetiological factors which cause this condition is unknown, as is each cause's frequency. The objective of this study was to identify all causes of amusia, and to measure each of their frequencies. systematic review was conducted by search of multiple databases for articles related to the aetiology of amusic auditory dysfunction. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for reporting of systematic reviews were followed, utilizing the PRISMA checklist and PRISMA flowchart methodology. Retrospective medical database review. evidence yielded from the systematic review process. The initial search protocol identified 5723 articles. Application of a classification review filter and exclusion of irrelevant or duplicates led to the initial identification of 56 relevant studies which detailed 301 patients. However, these studies were of poor quality. Because of this, synthesis and statistical analysis were not appropriate. Although initially a large number of relevant studies were identified, and might point in future to potential diagnostic categories, it was not appropriate to synthesise and analyse them due to poor quality, considerable heterogeneity and small numbers. This suggests that large, high quality studies focussed directly on understanding the aetiology of amusia are required.

  20. Phenomenological models of raft structure (United States)

    Shirotori, H.; Komura, S.; Kato, T.; Olmsted, P. D.


    We propose two phenomenological models describing the phase behavior of lipid-lipid systems and lipid-cholesterol systems in order to understand the "rafts" in cell membranes. In our models, the coupling between the lateral phase separation and the internal degree of freedom of a lipid membrane is considered. The calculated phase diagrams are in semiquantitative agreement with the experimental phase diagrams.

  1. New perspectives on phenomenological decoherence

    International Nuclear Information System (INIS)

    Melo, Fernando Vaz de; Guzzo, Marcelo Moraes; Peres, Orlando Luis Goulart


    Decoherence showed to be a powerful tool in helping to solve the atmospheric Neutrino problem. However a complete analysis was not yet done. In this work we present all the possibilities concerning phenomenological decoherence linked to Neutrino 'problem'. Its possibilities and differences are stressed out in a effort to clarify the whole phenomena. (author)

  2. Alpha Theta Meditation: Phenomenological, neurophysiologic ...

    African Journals Online (AJOL)

    Alpha Theta Meditation: Phenomenological, neurophysiologic, mindfulness, mood, health and sport implications. ... the single alpha theta meditation was associated with elevated alpha and theta activity, as well as decrease in negative mood perceptions, especially with regard to anxiety, sadness and confusion scores.

  3. Phenomenology and the Empirical Turn

    NARCIS (Netherlands)

    Zwier, Jochem; Blok, Vincent; Lemmens, Pieter


    This paper provides a phenomenological analysis of postphenomenological philosophy of technology. While acknowledging that the results of its analyses are to be recognized as original, insightful, and valuable, we will argue that in its execution of the empirical turn, postphenomenology forfeits

  4. The status of supersymmetry phenomenology

    Indian Academy of Sciences (India)

    The status of supersymmetry phenomenology. AMITAVA DATTA. Department of Physics, Jadavpur University, Calcutta 700 032, India. Present Address: Department of Physics, Visva Bharati, Santiniketan 731 235, India. Abstract. In this brief review the following topics are discussed: Direct searches for SUSY in mSUGRA: a ...

  5. Interpretive Hermeneutic Phenomenology: Clarifying Understanding ...

    African Journals Online (AJOL)

    The philosophical orientation of Gadamerian hermeneutic phenomenology is explored in this paper. Gadamer offers a hermeneutics of the humanities that differs significantly from models of the human sciences historically rooted in scientific methodologies. In particular, Gadamer proposes that understanding is first a mode ...

  6. Investigation into breath meditation: Phenomenological ...

    African Journals Online (AJOL)

    This integral heuristic phenomenological investigation records participants' experiences of a single session of breath meditation with special reference to psychotherapy and sport psychology. There were 8 participants, 4 men and 4 women, with mean age of 45 years and age range from 31 to 62 years. Various breathing ...

  7. Some Reflections in Phenomenology and Psychoanalysis | Hsu ...

    African Journals Online (AJOL)

    This paper examines the origin of phenomenology, and delineates several of its significant developments and refractions, in order to arrive at a renewed conception of phenomenological theory and practice: a future phenomenology that can, it is argued, articulate productively with certain grounds opened up by ...

  8. Empirical Phenomenology: A Qualitative Research Approach (The ...

    African Journals Online (AJOL)

    This paper introduces the philosophical foundation and practical application of empirical phenomenology in social research. The approach of empirical phenomenology builds upon the phenomenology of the philosophers Edmund Husserl and Martin Heidegger and the sociologist Alfred Schütz, but considers how their ...

  9. Learning from Twentieth Century Hermeneutic Phenomenology for ...

    African Journals Online (AJOL)

    The implications of commonalities in the contributions of five key thinkers in twentieth century phenomenology are discussed in relation to both original aims and contemporary projects. It is argued that, contrary to the claims of Husserl, phenomenology can only operate as hermeneutic phenomenology. Hermeneutics arose ...


    Directory of Open Access Journals (Sweden)

    Mallikarjun R. Patil


    Full Text Available BACKGROUND Acute non-traumatic coma is one of the most common paediatric emergencies, which arouses much anxiety and apprehension in both parents and physicians. Due to heterogeneity of causes in these patients, prediction of outcome is difficult and unfortunately no single clinical, laboratory or electrophysiological parameters singly predict their outcome. Aetiology of nontraumatic coma varies depending on different geographical area. We have attempted to find the incidence, aetiology and outcome and delineate neurological signs to predict the prognosis in this study. The aim of this study is to study the incidence, aetiology and outcome of non-traumatic coma in children. MATERIALS AND METHODS 100 consecutive cases of non-traumatic coma between 5months and 15 years of age were selected for the study. Clinical signs and findings were recorded at admission (‘0’ Hr and after ‘48’ Hrs. of hospital stay. Aetiology of coma is determined on the basis of clinical history, examination and relevant laboratory investigations by the treating physician. These children were followed up till the death in the hospital or discharged from the hospital. Discharged patients were asked for followup after 4 weeks. During this period, all of them were evaluated by formal neurological examination and for special sensory involvement. The neurological outcomes were categorised into 6 groups (I-VI based on the severity of neurological involvement. Chisquare test was applied to determine the predictors of outcome. RESULTS 1. The incidence of non-traumatic coma in our hospital based study was 8.02% of all paediatric admissions and 21.64% of all PICU admissions. 2. CNS infections contributed the majority (58% of cases. (Dengue encephalitis-28%, viral encephalitis-12%, TB meningitis-8%, pyogenic meningitis- 6%, Shigella encephalopathy-3% and cerebral malaria-1%. 3. Other non-infectious aetiologies were toxic and metabolic group- 21%, post status epilepticus- 9

  11. Naturalizing phenomenology - A philosophical imperative. (United States)

    Harney, Maurita


    Phenomenology since Husserl has always had a problematic relationship with empirical science. In its early articulations, there was Husserl's rejection of 'the scientific attitude', Merleau-Ponty's distancing of the scientifically-objectified self, and Heidegger's critique of modern science. These suggest an antipathy to science and to its methods of explaining the natural world. Recent developments in neuroscience have opened new opportunities for an engagement between phenomenology and cognitive science and through this, a re-thinking of science and its hidden assumptions more generally. This is so partly because of the shortcomings of conventional mechanistically-conceived science in dealing with complex and dynamic phenomena such as climate change, brain plasticity, the behaviour of collectives, the dynamics of various microbiological processes, etc. But it is also due to recent phenomenological scholarship focussed on the 'embodied' phenomenology of Husserl's Ideen II and Merleau Ponty's later ontology of nature which have helped to extend the insights of phenomenology beyond the narrowly 'human' to an understanding of nature (which includes the human) more generally. Thus re-contextualised, phenomenology is well placed to examine some of the assumptions that give rise to the reductionism and associated scientism which has characterised conventional science in its approach to the study of natural processes. In light of this, it might be suggested that the 'anti-science' of early articulations of phenomenology is more a hostility to the underlying assumptions of science as conventionally understood than to science itself - that it is scientism rather than science that is targeted. In this paper, I aim to show how a phenomenological naturalism might be seen as a necessary step towards the development of a non-reductionist and non-scientistic approach to scientific inquiry. A key to this is a reconceptualization of nature as inclusive of meanings and of mind. It

  12. Phenomenological aspects of mirage mediation

    International Nuclear Information System (INIS)

    Loewen, Valeri


    We consider the possibility that string theory vacua with spontaneously broken supersymmetry and a small positive cosmological constant arise due to hidden sector matter interactions, known as F-uplifting/F-downlifting. We analyze this procedure in a model-independent way in the context of type IIB and heterotic string theory. Our investigation shows that the uplifting/downlifting sector has very important consequences for the resulting phenomenology. Not only does it adjust the vacuum energy, but it can also participate in the process of moduli stabilization. In addition, we find that this sector is the dominant source of supersymmetry breaking. It leads to a hybrid mediation scheme and its signature is a relaxed mirage pattern of the soft supersymmetry breaking terms. The low energy spectra exhibit distinct phenomenological properties and di er from conventional schemes considered so far. (orig.)

  13. Phenomenology of unified gauge theories

    International Nuclear Information System (INIS)

    Ellis, J.


    Part I of these lectures treats the standard Glashow-Weinberg-Salam model of weak and electromagnetic interactions, discussing in turn its basic structure and weak neutral currents, charged currents, mixing angles and CP violation, and the phenomenology of weak vector and Higgs bosons. Part II of the lectures discusses the structure of theories of dynamical symmetry breaking such as technicolour, phenomenological consequences, frustrations and alternatives. The third part of these lectures offers the standard menu of grand unified theories (GUTs) of the strong, weak and electromagnetic interactions, including an hors d'oeuvre of constraints on the parameters of the standard model, a main course of baryon number violating processes, and desserts which violate lepton number and CP. The fourth and final part goes through different attempts to remedy the inadequacies of previous theories by invoking supersymmetry and reaching out towards gravitation. (orig./HSI)

  14. A phenomenological approach to psychoprosthetics. (United States)

    Mills, Frederick B


    The phenomenology of human embodiment can advance the practitioner's understanding of the lived human body and in particular, what it means to incorporate a prosthetic device into one's body. In order for a prosthesis to be incorporated into the lived body of the patient, the prosthesis must arguably be integrated into the body schema. This article uses the phenomenology of Maurice Merleau-Ponty and others to identify three of the necessary conditions of embodiment that determine the body schema: corporeal understanding, transparency and sensorimotor feedback. It then examines the structure of each of these conditions of embodiment and how they impact the lived body's incorporation of prostheses and other artifacts. [Box: see text].

  15. Phenomenological aspects of mirage mediation

    Energy Technology Data Exchange (ETDEWEB)

    Loewen, Valeri


    We consider the possibility that string theory vacua with spontaneously broken supersymmetry and a small positive cosmological constant arise due to hidden sector matter interactions, known as F-uplifting/F-downlifting. We analyze this procedure in a model-independent way in the context of type IIB and heterotic string theory. Our investigation shows that the uplifting/downlifting sector has very important consequences for the resulting phenomenology. Not only does it adjust the vacuum energy, but it can also participate in the process of moduli stabilization. In addition, we find that this sector is the dominant source of supersymmetry breaking. It leads to a hybrid mediation scheme and its signature is a relaxed mirage pattern of the soft supersymmetry breaking terms. The low energy spectra exhibit distinct phenomenological properties and di er from conventional schemes considered so far. (orig.)

  16. Clinical presentation, aetiology and complications of pancreatitis in children

    International Nuclear Information System (INIS)

    Fayyaz, Z.; Cheema, H.A.; Suleman, H.; Hashmi, M.A.; Parkash, A.; Waheed, N.


    Background: Childhood Pancreatitis is an uncommon but serious condition with incidence on the rise. It manifests as acute or chronic form with epigastric pain, vomiting and elevated serum -amylase and lipase. This study was conducted with the aim to determine the clinical presentation, aetiology, and complications of pancreatitis in children. Method: This descriptive case series was conducted in the Department of Paediatric Gastroenterology, Hepatology and Nutrition, The Children's Hospital and the Institute of Child Health, Lahore from 1st January to 31st December 2014. Seventy-two patients up to the age of 15 years having abdominal pain, Amylase >200 IU/L and/or lipase >165 IU/L, with features of acute or chronic pancreatitis on abdominal imaging; were included in study. Data analysis was done using SPSS-20. Results: Of the total 72 patients, 43 (60 percentage) had acute pancreatitis, males were 25 (58 percentage) and females 18 (42 percentage) and chronic pancreatitis was diagnosed in 29 (40 percentage), males 10 (34 percentage) and females 19 (66 percentage). Common clinical features were abdominal pain (100 percentage), nausea and vomiting (79 percentage). Common aetiologies were idiopathic (40 percentage) while choledochal cyst 8 percentage, hyperlipidaemia 7 percentage, biliary tract stones/sludge 7 percentage and abdominal trauma 6percentage. Complications were more frequently associated with acute pancreatitis (60 percentage) than with chronic pancreatitis (34 percentage). Common complications were pseudo-pancreatic cyst (36 percentage), ascites (17 percentage) and pleural effusion (4 percentage). Conclusion: Abdominal pain, nausea and vomiting were common presenting features of childhood pancreatitis. Common aetiologies were idiopathic hyperlipidemia, biliary tract stones/sludge, choledochal cyst and abdominal trauma. Common complications were Pseudo-pancreatic cyst, ascites and pleural effusion. (author)

  17. Phenomenology of the Higgs boson

    International Nuclear Information System (INIS)

    Ali, A.


    The phenomenology of the standard Weinberg-Salam Higgs boson is reviewed with particular emphasis on production mechanisms in high energy e + e - and hadron-hadron collisions. The production processes relevant for the ISABELLE and TEVATRON energies are discussed and their backgrounds estimated. It is argued that the toponium production and radiative decay provides the most hopeful reaction to detect a Higgs in both the e + e - and the hadron-hadron machines. (orig.)

  18. Myelitis: Differences between multiple sclerosis and other aetiologies. (United States)

    Presas-Rodríguez, S; Grau-López, L; Hervás-García, J V; Massuet-Vilamajó, A; Ramo-Tello, C


    Myelitis can appear as an initial symptom in the context of demyelinating diseases, systemic inflammatory diseases, and infectious diseases. We aim to analyse the differences between myelitis associated with multiple sclerosis (MS) and myelitis resulting from other aetiologies. Single-centre, retrospective analysis of patients with initial myelitis (2000-2013). Demographic, aetiological, clinical, radiological and prognostic variables were analysed and compared between patients with myelitis from MS and those with myelitis due to other aetiologies. We included 91 patients; mean follow-up was 7 years. Diagnoses were as follows: MS 57 (63%), idiopathic transverse myelitis 22 (24%), associated systemic diseases 6 (7%), and other diagnoses (6%). Myelitis due to MS was associated with younger age of onset (35 ± 11 vs. 41 ± 13; P = .02), more pronounced sphincter involvement (40.4 vs. 27.3%; P=.05), greater multifocal involvement in spinal MRI (77.2 vs. 26.5%; P=.001), shorter lesion extension (2.4 vs. 1.4 vertebral segments; P=.001), cervical location (82.5 vs. 64.7%; P=.05) and posterior location (89.5 vs. 41.2%; P=.001). Myelitis due to other aetiologies more frequently showed anterior location (47.1 vs. 24.6%; P=.02), and central cord involvement (47.1 vs. 14.1%; P=.001), with better recovery at one year of follow up (EDSS 2.0 vs. 1.5; P=.01). Multivariate analysis showed that multifocal spinal cord involvement (OR 9.38, 95% CI: 2.04-43.1) and posterior cord involvement (OR 2.16, 95% CI: 2.04-2.67) were independently associated with the diagnosis of MS. A high percentage of patients with an initial myelitis event will be diagnosed with MS. The presence of multifocal and posterior spinal cord lesions was significantly associated with the diagnosis of MS. Copyright © 2015 Sociedad Española de Neurología. Published by Elsevier España, S.L.U. All rights reserved.

  19. Epidemiology, aetiology, diagnosis and screening of lung cancer

    International Nuclear Information System (INIS)

    Berzinec, P.


    Lung cancer is the leading cause of cancer death globally. Smoking causes about 90 % of all lung cancer cases. Passive, i.e. involuntary smoking has been confirmed to enhance the risk of lung cancer in exposed people. Individual susceptibility is one of important factors in lung cancer formation. New knowledge in epidemiology and aetiology of lung cancer gives new possibilities in diagnostic and screening of this disease. Results of large randomised trials aimed at new technologies in lung cancer screening will be available in a few years. (author)

  20. Importance of pituitary hormones in aetiology of diabetic ketoacidosis

    International Nuclear Information System (INIS)

    Barnes, A.J.; Kohner, E.M.; Bloom, S.R.; Johnston, D.G.; Alberti, K.G.M.M.; Smythe, P.


    The role of pituitary hormones in the aetiology of diabetic ketoacidosis was examined by withdrawing insulin from five pituitary-ablated diabetics for a 12-hour period. The rise in blood glucose and ketone-body concentrations was markedly retarded in these patients when compared with five matched juvenile-type diabetic controls with normal pituitary function. When cortisol replacement in the pituitary-ablated patients was increased to reproduce the high plasma concentrations found in severe ketoacidosis, blood ketones and glucose were increased but were still significantly lower than in the control diabetics. It is concluded that pituitary hormones may be important in the development of diabetic ketoacidosis. (author)

  1. Left atrio-esophageal fistula of a possibly iatrogenic aetiology. (United States)

    Arkuszewski, Piotr; Barzdo, Maciej; Ostrowski, Stanisław; Szram, Stefan; Berent, Jarosław


    The study presents an exceptionally rare case of an esophago-left atrial fistula, which was diagnosed during a forensic post-mortem examination. Due to complex nature of the disease and many attempts to cure the patient, the authors did not manage to identify the aetiology of the fistula. It was only implied that the fistula might have been a distant complication of intraoperative endocardial ablation or it might have appeared as a consequence of perforation of the esophageal wall or left atrial wall of the enlarged heart with the end of an intubation tube or nasogastric tube. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  2. Painful bladder syndrome/interstitial cystitis: Aetiology, evaluation and management

    Directory of Open Access Journals (Sweden)

    William Rourke


    Full Text Available Interstitial cystitis or bladder pain syndrome (BPS is often a chronic debilitating condition characterised by predominantly storage symptoms and associated frequently with pelvic pain that varies with bladder filling. The aetiology is uncertain as the condition occurs in the absence of a urinary tract infection or other obvious pathology. Resulting discomfort may vary and ranges from abdominal tenderness to intense bladder spasms. Diagnosis and management of this syndrome may be difficult and is often made by its typical cystoscopic features. This review discusses the diagnosis and management of interstitial cystitis according to the current available best evidence and advises a multimodal approach in its management.

  3. Phenomenology of stochastic exponential growth (United States)

    Pirjol, Dan; Jafarpour, Farshid; Iyer-Biswas, Srividya


    Stochastic exponential growth is observed in a variety of contexts, including molecular autocatalysis, nuclear fission, population growth, inflation of the universe, viral social media posts, and financial markets. Yet literature on modeling the phenomenology of these stochastic dynamics has predominantly focused on one model, geometric Brownian motion (GBM), which can be described as the solution of a Langevin equation with linear drift and linear multiplicative noise. Using recent experimental results on stochastic exponential growth of individual bacterial cell sizes, we motivate the need for a more general class of phenomenological models of stochastic exponential growth, which are consistent with the observation that the mean-rescaled distributions are approximately stationary at long times. We show that this behavior is not consistent with GBM, instead it is consistent with power-law multiplicative noise with positive fractional powers. Therefore, we consider this general class of phenomenological models for stochastic exponential growth, provide analytical solutions, and identify the important dimensionless combination of model parameters, which determines the shape of the mean-rescaled distribution. We also provide a prescription for robustly inferring model parameters from experimentally observed stochastic growth trajectories.

  4. A comparison of phenylketonuria with attention deficit hyperactivity disorder: do markedly different aetiologies deliver common phenotypes? (United States)

    Stevenson, M; McNaughton, N


    Phenylketonuria (PKU) is a well-defined metabolic disorder arising from a mutation that disrupts phenylalanine metabolism and so produces a variety of neural changes indirectly. Severe cognitive impairment can be prevented by dietary treatment; however, residual symptoms may be reported. These residual symptoms appear to overlap a more prevalent childhood disorder: Attention Deficit/Hyperactivity Disorder (ADHD). However, the aetiology of ADHD is a vast contrast to PKU: it seems to arise from a complex combination of genes; and it has a substantial environmental component. We ask whether these two disorders result from two vastly different genotypes that converge on a specific core phenotype that includes similar dysfunctions of Gray's (Gray, 1982) Behavioural Inhibition System (BIS), coupled with other disorder-specific dysfunctions. If so, we believe comparison of the commonalities will allow greater understanding of the neuropsychology of both disorders. We review in detail the aetiology, treatment, neural pathology, cognitive deficits and electrophysiological abnormalities of PKU; and compare this with selected directly matching aspects of ADHD. The biochemical and neural pathologies of PKU and ADHD are quite distinct in their causes and detail; but they result in the disorder in the brain of large amino acid levels, dopamine and white matter that are very similar and could explain the overlap of symptoms within and between the PKU and ADHD spectra. The common deficits affect visual function, motor function, attention, working memory, planning, and inhibition. For each of PKU and ADHD separately, a subset of deficits has been attributed to a primary dysfunction of behavioural inhibition. In the case of ADHD (excluding the inattentive subtype) this has been proposed to involve a specific failure of the BIS; and we suggest that this is also true of PKU. This accounts for a substantial proportion of the parallels in the superficial symptoms of both disorders and

  5. Philosophy of phenomenology: how understanding aids research. (United States)

    Converse, Mary


    To assist the researcher in understanding the similarities and differences between the Husserlian and Heideggerian philosophies of phenomenology, and how that philosophy can inform nursing research as a useful methodology. Nurse researchers using phenomenology as a methodology need to understand the philosophy of phenomenology to produce a research design that is philosophically congruent. However, phenomenology has a long and complex history of development, and may be difficult to understand and apply. The author draws from Heidegger (1962), Gadamer (2004), and nurse scholars and methodologists. To give the reader a sense of the development of the philosophy of phenomenology, the author briefly recounts its historical origins and interpretations, specifically related to Husserl, Heidegger and Gadamer. The author outlines the ontological and epistemological assumptions of Husserlian and Heideggerian phenomenology and guidance for methodology inspired by these philosophers. Difficulties with engaging in phenomenological research are addressed, especially the processes of phenomenological reduction and bracketing, and the lack of clarity about the methods of interpretation. Despite its complexity, phenomenology can provide the nurse researcher with indepth insight into nursing practice. An understanding of phenomenology can guide nurse researchers to produce results that have meaning in nursing patient care.

  6. Imaging in mediastinitis: a systematic review based on aetiology

    Energy Technology Data Exchange (ETDEWEB)

    Akman, C. E-mail:; Kantarci, F.; Cetinkaya, S


    Mediastinitis refers to inflammation of the tissues located in the middle chest cavity. It can be secondary to infectious or non-infectious causes and depending on the aetiology may be acute or chronic. The majority of cases of acute mediastinitis are secondary to oesophageal perforation and open chest surgery. Less common causes include tracheal, bronchial perforation or direct extension of infection from adjacent tissues. Chronic or slowly developing mediastinitis mostly arise from tuberculosis, histoplasmosis, other fungal infections, cancer, or sarcoidosis. In a minority of cases the aetiology is lymphatic obstruction or an autoimmune disease. Radiological imaging plays an essential role in the diagnosis and therapeutic approach to mediastinitis. Generally, the initial radiological work-up includes radiographic studies either with or without contrast material. However, conventional chest radiography may be misleading in the diagnosis of mediastinitis. Cross-sectional imaging techniques are generally required for diagnosis and evaluation of the site and extent of mediastinal involvement. Computed tomography and magnetic resonance imaging may also guide the choice of the optimal therapeutic approach.

  7. Embodiment and psychopathology: a phenomenological perspective. (United States)

    Fuchs, Thomas; Schlimme, Jann E


    To survey recent developments in phenomenological psychopathology. We present the concept of embodiment as a key paradigm of recent interdisciplinary approaches from the areas of philosophy, psychology, psychiatry and neuroscience. This requires a short overview on the phenomenological concept of embodiment; in particular, on the distinction of subject and object body. A psychopathology of embodiment may be based on these and other distinctions, in particular on a polarity of disembodiment and hyperembodiment, which is illustrated by the examples of schizophrenia and depression. Recent contributions to phenomenological accounts of these disorders are presented. Finally, the study discusses the relationship of phenomenological and neuropsychiatric perspectives on embodiment. A phenomenology of embodiment may be combined with enactive approaches to cognitive neuroscience in order to overcome dualist concepts of the mind as an inner realm of representations that mirror the outside world. Phenomenological and ecological concepts of embodiment should also be conjoined to enable a new, advanced understanding of mental illness.





    The subject of this article concerns the what, the how and the whyof moral phenomenology. The first question we take into consideration is „What is moral phenomenology”? The second question which arises is „How to pursue moral phenomenology”? The third question is „Why pursue moral phenomenology”? We will analyze the study Moral phenomenology:foundation issues1, by which the American phenomenologist Uriah Kriegel aims three lines of research: the definition of moral phenomenology and the desc...

  9. Phenomenology And Media Lıteracy


    Ayhan, Çise; Domitran, Zrinka; Radunovic, Nikola; Tavakoli, Sepehr Dadjoi


    Is phenomenology a movement or concept? Is it a research method in human science? Different approaches have been introduced with the term of phenomenology, even it has been named as movement.It is commonly understood in either of two ways: as a disciplinary field in philosophy, or as a movement. In phenomenologist's point of view, “Phenomenology is the theory of experiences in general, inclusive of all matters, whether real or intentional, given in experiences, and evidently di...

  10. Phenomenology is not Phenomenalism. Is there such a thing as phenomenology of sport?

    Directory of Open Access Journals (Sweden)

    Jan Halák


    Full Text Available Background: The application of the philosophical mode of investigation called "phenomenology" in the context of sport. Objective: The goal is to show how and why the phenomenological method is very often misused in sport-related research. Methods: Interpretation of the key texts, explanation of their meaning. Results: The confrontation of concrete sport-related texts with the original meaning of the key phenomenological notions shows mainly three types of misuse - the confusion of phenomenology with immediacy, with an epistemologically subjectivist stance (phenomenalism, and with empirical research oriented towards objects in the world. Conclusions: Many of the discussed authors try to take over the epistemological validity of phenomenology for their research, which itself is not phenomenological, and it seems that this is because they are lacking such a methodological foundation. We believe that an authentically phenomenological analysis of sport is possible, but it must respect the basic distinctions that differentiate phenomenology from other styles of thinking.


    Energy Technology Data Exchange (ETDEWEB)

    Jessie L. Bonner; Brian Stump; Mark Leidig; Heather Hooper; Xiaoning (David) Yang; Rongmao Zhou; Tae Sung Kim; William R. Walter; Aaron Velasco; Chris Hayward; Diane Baker; C. L. Edwards; Steven Harder; Travis Glenn; Cleat Zeiler; James Britton; James F. Lewkowicz


    The Arizona Source Phenomenology Experiments (SPE) have resulted in an important dataset for the nuclear monitoring community. The 19 dedicated single-fired explosions and multiple delay-fired mining explosions were recorded by one of the most densely instrumented accelerometer and seismometer arrays ever fielded, and the data have already proven useful in quantifying confinement and excitation effects for the sources. It is very interesting to note that we have observed differences in the phenomenology of these two series of explosions resulting from the differences between the relatively slow (limestone) and fast (granodiorite) media. We observed differences at the two SPE sites in the way the rock failed during the explosions, how the S-waves were generated, and the amplitude behavior as a function of confinement. Our consortium's goal is to use the synergy of the multiple datasets collected during this experiment to unravel the phenomenological differences between the two emplacement media. The data suggest that the main difference between single-fired chemical and delay-fired mining explosion seismograms at regional distances is the increased surface wave energy for the latter source type. The effect of the delay-firing is to decrease the high-frequency P-wave amplitudes while increasing the surface wave energy because of the longer source duration and spall components. The results suggest that the single-fired explosions are surrogates for nuclear explosions in higher frequency bands (e.g., 6-8 Hz Pg/Lg discriminants). We have shown that the SPE shots, together with the mining explosions, are efficient sources of S-wave energy, and our next research stage is to postulate the possible sources contributing to the shear-wave energy.

  12. Bullies and Victims: A Phenomenological Study (United States)

    Omizo, Michael M.; Omizo, Sharon A.; Baxa, Gari-Vic C. O.; Miyose, Ross J.


    This study presents the results of a phenomenological study with sixteen elementary school children identified as bullies or victims. Implications for school counselors and educators are also discussed.

  13. Phenomenological implementations of TMD evolution

    Energy Technology Data Exchange (ETDEWEB)

    Boglione, Mariaelena [University of Turin, Torino, Italy; Gonzalez Hernandez, Jose Osvaldo [University of Virginia, Charlottesville, VA; Melis, Stefano [European Centre for Theoretical Studies; Prokudin, Alexey [JLAB


    Although the theoretical set-up of TMD evolution appears to be well established, its phenomenological implementations still require special attention, particularly as far as the interplay between perturbative and non-perturbative contributions is concerned. These issues have been extensively studied in Drell-Yan processes, where they seem to be reasonably under control. Instead, applying the same prescriptions and methodologies to Semi-Inclusive Deep Inelastic (SIDIS) processes is, at present, far from obvious. Some of the controversies related to the applications of TMD Evolution to SIDIS processes will be discussed with practical examples, exploring different kinematical configurations of SIDIS experiments.

  14. Recent Trends in Superstring Phenomenology

    CERN Document Server

    Bianchi, Massimo


    We review for non-experts possible phenomenological scenari in String Theory. In particular we focus on vacuum configurations with intersecting and/or magnetized unoriented D-branes. We will show how a TeV scale tension may be compatible with the existence of Large Extra Dimensions and how anomalous U(1)'s can give rise to interesting signatures at LHC or in cosmic rays. Finally, we discuss unoriented D-brane instantons as a source of non-perturbative effects that can contribute to moduli stabilization and susy braking in combination with fluxes. We conclude with an outlook and directions for future work.

  15. Next Generation Transport Phenomenology Model (United States)

    Strickland, Douglas J.; Knight, Harold; Evans, J. Scott


    This report describes the progress made in Quarter 3 of Contract Year 3 on the development of Aeronomy Phenomenology Modeling Tool (APMT), an open-source, component-based, client-server architecture for distributed modeling, analysis, and simulation activities focused on electron and photon transport for general atmospheres. In the past quarter, column emission rate computations were implemented in Java, preexisting Fortran programs for computing synthetic spectra were embedded into APMT through Java wrappers, and work began on a web-based user interface for setting input parameters and running the photoelectron and auroral electron transport models.

  16. Quantum and classical phenomenological universalities (United States)

    Molski, Marcin


    The quantum Q2 class of phenomenological universalities (PU) is extended to include exact solutions and minimum uncertainty coherent states of Hulthen, Kratzer-Fues, Tipping and generalized Kratzer-Fues-Tipping oscillators. In the dissociation (quasi-quantum) limit the solutions obtained generate the extended U2 class of PU including West-Brown-Enquist universal growth curve and temporal (spatial) fractal functions widely used in the field of life sciences and physics. It will be shown that the PU concept seems to be a valuable methodology for deriving the new forms of potential energy functions with possible applications in theoretical analysis of molecular spectra.

  17. Has the aetiology of ischaemic stroke changed in the past decades? Analysis and comparison of data from current and historical stroke databases. (United States)

    Sánchez-Larsen, Á; García-García, J; Ayo-Martín, O; Hernández-Fernández, F; Díaz-Maroto, I; Fernández-Díaz, E; Monteagudo, M; Segura, T


    We aimed to determine whether the aetiology of ischaemic stroke has changed in recent years and, if so, to ascertain the possible reasons for these changes. We analysed the epidemiological history and vascular risk factors of all patients diagnosed with ischaemic stroke at Complejo Hospitalario Universitario de Albacete (CHUA) from 2009 to 2014. Ischaemic stroke subtypes were established using the TOAST criteria. Our results were compared to data from the classic Stroke Data Bank (SDB); in addition, both series were compared to those of other hospital databases covering the period between the two. We analysed 1664 patients (58% were men) with a mean age of 74 years. Stroke aetiology in both series (CHUA, SDB) was as follows: atherosclerosis (12%, 9%), small-vessel occlusion (13%, 25%), cardioembolism (32%, 19%), stroke of other determined aetiology (3%, 4%), and stroke of undetermined aetiology (40%, 44%). Sixty-three percent of the patients from the CHUA and 42% of the patients from the SDB were older than 70 years. Cardioembolic strokes were more prevalent in patients older than 70 years in both series. Untreated hypertension was more frequent in the SDB (SDB = 31% vs CHUA = 10%). The analysis of other databases shows that the prevalence of cardioembolic stroke is increasing worldwide. Our data show that the prevalence of lacunar strokes is decreasing worldwide whereas cardioembolic strokes are increasingly more frequent in both our hospital and other series compared to the SDB. These differences may be explained by population ageing and the improvements in management of hypertension and detection of cardioembolic arrhythmias in stroke units. Copyright © 2016 Sociedad Española de Neurología. Publicado por Elsevier España, S.L.U. All rights reserved.

  18. Reflection about the Phenomenological Claim Book Review of Jose Ruiz: About the Meaning of Phenomenology


    Alejandro Rojas Jiménez


    Commentary on the attempt to save the phenomenological claim (the meaning of phenomenology) that Jose Ruiz makes in his book, trying to distinguish noesis from noema. This comment is written from the view that the milestones of phenomenology cannot be considered regardless of their methodical aspect

  19. Villitis of unknown aetiology: correlation of recurrence with clinical outcome.

    LENUS (Irish Health Repository)

    Feeley, L


    Villitis of unknown aetiology (VUA) is associated with adverse pregnancy outcome. Consequently, an ability to predict recurrence could be clinically relevant. We examined placentas where villitis was diagnosed in a previous pregnancy to establish the risk of recurrence and outcome. A total of 304 cases of VUA were diagnosed in our laboratory over a 4-year period. Subsequently, 19 of this cohort had a second placenta examined histologically. Recurrence and clinical outcome were recorded. Villitis recurred in 7 of 19 cases (37%). There was a high level of adverse pregnancy outcome in this cohort overall, characterised by small for gestational age infants and stillbirth, particularly in cases with high-grade villitis. We identified recurrent villitis more frequently than previously reported. Our findings confirm an association between high-grade villitis and poor outcome. Adequately powered prospective studies are required to determine if enhanced surveillance of subsequent pregnancies is indicated following a diagnosis of villitis.

  20. Dermatoglyphics in childhood leukaemia: a guide to prognosis and aetiology? (United States)

    Till, M.; Larrauri, S.; Smith, P. G.


    The results of analysis of the dermatoglyphics of 152 children with acute lymphoblastic leukaemia (ALL) (and the first-degree relatives of 54 of them) contrast with those of 31 children with acute myeloblastic leukaemia (AML) (and the first-degree relatives of 25 of them). In ALL our findings suggest that neither genetic susceptibility nor an environmental factor, effective during the early antenatal period, is of aetiological importance; but the response to treatment, assessed as length of first remission, was found to be related to the amount of fingertip pattern. This may have clinical application. In AML there is evidence of a genetically determined factor carrying a high risk of the development of the disease, in that a member of each of 5 different families of the 25 studied bore a rare hypothenar pattern, compared with none in 75 control families. No dermatoglyphic features were of prognostic significance in AML. PMID:277206

  1. Bovine pododermatitis aseptica diffusa (laminitis) aetiology, pathogenesis, treatment and control. (United States)

    Mgasa, M N


    Pododermatitis aseptica diffusa (laminitis) is a major cause of lameness and discomfort to cattle with resultant economic losses. The disease is a result of multifactorial aetiology most of which is not clearly understood. Feeding readily fermentable carbohydrates to unaccustomed cattle predisposes to the disease. Histamine, lactic acid and endotoxins are believed to be involved. Systemic acidosis, histaminosis and endotoxaemia are thought to produce the pathophysiological characteristics of laminitis. The diagnosis is primarily based on the observation of symmetrical and bilateral lesions in hooves and characteristic lameness affecting all feet. Gross lesions include concavity of the dorsal wall, discolorations in the sole and rotation of the pedal bone. Degenerative changes and arteriosclerosis are constant histological findings in the corium, with chronic thrombi and chronic granulation tissue. The disease may be treated conservatively and by application of cyclo-oxygenase inhibiting non-steroidal anti-inflammatory drugs and prevented or controlled by proper feeding and management practices.

  2. The aetiology of cardiovascular disease: a role for mitochondrial DNA? (United States)

    Venter, Marianne; van der Westhuizen, Francois H; Elson, Joanna L


    Cardiovascular disease (CVD) is a world-wide cause of mortality in humans and its incidence is on the rise in Africa. In this review, we discuss the putative role of mitochondrial dysfunction in the aetiology of CVD and consequently identify mitochondrial DNA (mtDNA) variation as a viable genetic risk factor to be considered. We then describe the contribution and pitfalls of several current approaches used when investigating mtDNA in relation to complex disease. We also propose an alternative approach, the adjusted mutational load hypothesis, which would have greater statistical power with cohorts of moderate size, and is less likely to be affected by population stratification. We therefore address some of the shortcomings of the current haplogroup association approach. Finally, we discuss the unique challenges faced by studies done on African populations, and recommend the most viable methods to use when investigating mtDNA variation in CVD and other common complex disease.

  3. [Dyskinesia in Parkinson's disease--major clinical features, aetiology, therapy]. (United States)

    Ellrichmann, G; Russ, H; Müller, T


    Parkinson's disease (PD), a slowly, progressive degenerative disorder of the central nervous system, which affects about ten million people world-wide, is currently treated symptomatically. Current treatment aim i. e. to balance the decreased dopamine turnover in striatal neurons. Chronic exposure to dopaminergic agents, however, supports onset of motor complications and dyskinesia in the long term. Dyskinesia appear mainly as chorea, athetosis, dystonia, stereotypia, ballism or a combination. Sometimes excessive abnormal facial, body and limb movements depend on the overall dosage of dopaminergic substitution. This is why the main therapy is based on reducing the total dosage of dopaminergic substances. Either alternative or additional well-tried substances like apomorphine, amantadine or clozapine are used. New possibilities in treatment emerge from substances like sarizotan, istradefylline, fipampezol or talampanel. Even so disability and reduced quality of life in PD patients and their caregivers may exist. This survey describes the major clinical features, aetiology and demographics of treatment-associated dyskinesia in PD.

  4. Levels of uric acid in erectile dysfunction of different aetiology. (United States)

    Barassi, Alessandra; Corsi Romanelli, Massimiliano Marco; Pezzilli, Raffaele; Dozio, Elena; Damele, Clara Anna Linda; Vaccalluzzo, Liborio; Di Dario, Marco; Goi, Giancarlo; Papini, Nadia; Massaccesi, Luca; Colpi, Giovanni Maria; Melzi d'Eril, Gian Vico


    Erectile dysfunction is a common disease characterized by endothelial dysfunction. The aetiology of ED is often multifactorial but evidence is being accumulated in favor of the proper function of the vascular endothelium that is essential to achieving and maintaining penile erection. Uric acid itself causes endothelial dysfunction via decreased nitric oxide production. This study aims to evaluate the serum uric acid (SUA) levels in 180 ED patients, diagnosed with the International Index of Erectile Function-5 (IIEF-5) and 30 non-ED control. Serum uric acid was analyzed with a commercially available kit using ModularEVO (Roche, Monza, Italy). Within-assay and between-assay variations were 3.0% and 6.0%, respectively. Out of the ED patients, 85 were classified as arteriogenic (A-ED) and 95 as non-arteriogenic (NA-ED) with penile-echo-color-Doppler. Uric acid levels (median and range in mg/dL) in A-ED patients (5.8, 4.3-7.5) were significantly higher (p uric acid levels in patients with mild A-ED (IIEF-5 16-20) and severe/complete A-ED (IIEF-5 ≤ 10) that were 5.4 (range 4.3-6.5) mg/dL and 6.8 (range 6.4-7.2) mg/dL, respectively. There was no difference between the levels of uric acid in patients with different degree of NA-ED. Our findings reveal that SUA is a marker of ED but only of ED of arteriogenic aetiology.

  5. Phenomenology between Pathos and Response

    Directory of Open Access Journals (Sweden)

    Bernhard Waldenfels


    Full Text Available The author calls phenomenological intentionality, into question while taking it, nevertheless, as a starting point. From the analysis of the meaning of phenomena he goes back to a pathic dimension which precedes them. What happens to us or affects us and to what we respond in different ways cannot be reduced to previous horizons. Between pathos and response, there is an irreducible cleft which constitutes a special sort of time-lag. What happens to us comes is always too early; our responses always come too late. Our experience is never completely up to date. In order to explore this pre-semantic and pre-pragmatic depth of experience we need a sort of responsive reduction, which guides all meaning toward something we respond to. In conclusion, the author evokes some areas in which such a revision of phenomenology shows its effects, namely the genesis of life in bioethics, the historical elaboration of memory and the experience of the Other.  

  6. 8. Prevalence of Epistaxis among Patients Receiving ...

    African Journals Online (AJOL)


    The aim of this study was thus to determine the prevalence, aetiology and treatment modalities of epistaxis among patients receiving otorhinolaryngology services at MNH and MOI. Materials and Methods: A cross-sectional, hospital based study was done to 427 patients at Muhimbili. National Hospital (MNH) and Muhimbili.

  7. Phenomenology as first philosophy | Allsobrook | South African ...

    African Journals Online (AJOL)

    The paper interprets phenomenology as a mode of inquiry that addresses fundamental questions of first philosophy, beyond the limitation of the practice by its leading theorists to the study of mere appearances. I draw on Adorno's critique of phenomenology to show that it has typically functioned as a mode of first ...

  8. Visual Arts as a Tool for Phenomenology

    Directory of Open Access Journals (Sweden)

    Anna S. CohenMiller


    Full Text Available In this article I explain the process and benefits of using visual arts as a tool within a transcendental phenomenological study. I present and discuss drawings created and described by four participants over the course of twelve interviews. Findings suggest the utility of visual arts methods within the phenomenological toolset to encourage participant voice through easing communication and facilitating understanding.

  9. Phenomenology and Otherness - on embodied encounters

    DEFF Research Database (Denmark)

    Simonsen, Kirsten; Koefoed, Lasse Martin

    Starting from phenomenology's notion of orientation towards and involvement with the other and the surrounding environment the paper want to pursue a development from the meeting and opening up to the universalized other of phenomenology towards a focus on encounters with particular others...

  10. Phenomenology, Hermeneutics and the study of indigenous ...

    African Journals Online (AJOL)

    In the quest for appropriate methods of studying religion, researchers in recent years have fiercely attacked phenomenology for its inadequacies in the academic study of religion. Phenomenology, as an approach, has been relegated to a relic in some departments of religious studies at Western universities. Yet in Africa ...

  11. Humanising Forces: Phenomenology in Science; Psychotherapy in ...

    African Journals Online (AJOL)


    The Indo-Pacific Journal of Phenomenology (IPJP) can be found at The IPJP is a joint project of Rhodes ... The present paper examines how the findings of a phenomenological study of psychotherapy reflects a movement by people in .... the particular in the general; the dance of the unique and the shared.

  12. Interdisciplinarity within Phenomenology | Embree | Indo-Pacific ...

    African Journals Online (AJOL)

    Recognition of phenomenological tendencies in several dozen disciplines beyond philosophy raises the question of how phenomenology in general might be defined prior to specification in terms of the agendas of the particular disciplines. After an attempt at an answer to this question, some observations concerning the ...

  13. Phenomenological Research Methods for Counseling Psychology (United States)

    Wertz, Frederick J.


    This article familiarizes counseling psychologists with qualitative research methods in psychology developed in the tradition of European phenomenology. A brief history includes some of Edmund Husserl's basic methods and concepts, the adoption of existential-phenomenology among psychologists, and the development and formalization of qualitative…

  14. Short article: Presence, extent and location of pancreatic necrosis are independent of aetiology in acute pancreatitis. (United States)

    Verdonk, Robert C; Sternby, Hanna; Dimova, Alexandra; Ignatavicius, Povilas; Koiva, Peter; Penttila, Anne K; Ilzarbe, Lucas; Regner, Sara; Rosendahl, Jonas; Bollen, Thomas L


    The most common aetiologies of acute pancreatitis (AP) are gallstones, alcohol and idiopathic. The impact of the aetiology of AP on the extent and morphology of pancreatic and extrapancreatic necrosis (EXPN) has not been clearly established. The aim of the present study was to assess the influence of aetiology on the presence and location of pancreatic necrosis in patients with AP. We carried out a post-hoc analysis of a previously established multicentre cohort of patients with AP in whom a computed tomography was available for review. Clinical data were obtained from the medical records. All computed tomographies were revised by the same expert radiologist. The impact of aetiology on pancreatic and EXPN was calculated. In total, 159 patients with necrotizing pancreatitis were identified from a cohort of 285 patients. The most frequent aetiologies were biliary (105 patients, 37%), followed by alcohol (102 patients, 36%) and other aetiologies including idiopathic (78 patients, 27%). No relationship was found between the aetiology and the presence of pancreatic necrosis, EXPN, location of pancreatic necrosis or presence of collections. We found no association between the aetiology of AP and the presence, extent and anatomical location of pancreatic necrosis.

  15. A Phenomenological Investigation of Adolescent Dating Relationships and Dating Violence Counseling Interventions (United States)

    Hays, Danica G.; Michel, Rebecca E.; Cole, Rebekah F.; Emelianchik, Kelly; Forman, Julia; Lorelle, Sonya; McBride, Rebecca; Sikes, April


    Despite the prevalence of dating violence, incidences often go unreported due to a lack of awareness among students as to appropriate dating behaviors. This phenomenology investigated how adolescents conceptualize and experience dating relationships. We explored adolescent females' definitions of healthy and abusive relationships, experiences with…

  16. The problem of arriving at a phenomenological description of memory loss. (United States)

    Moyle, W; Clinton, M


    This paper discusses a methodological difficulty that arose when uncovering the conscious experience of being nurtured as an in-patient with depression on a psychiatric ward. It considers the problem of arriving at a phenomenological description of memory loss in a patient who had undergone electroconvulsive therapy (ECT). The paper begins by describing the prevalence of depression and its significance for nurses working in in-patient settings. Examples of empirical research into memory loss in depression are used to show what researchers must set aside if they are to arrive at a phenomenological description of memory loss. The choice of a phenomenological approach to the wider study from which the methodological problem discussed here arose is then justified. The phenomena of memory is introduced to show the methodological significance of attempting to arrive at a phenomenological description of the statement made by one of the participants, a woman being treated as an in-patient for major depression. A possible description of the phenomena of memory loss based on the existential phenomenology of Sartre is offered to call into question the ability of researchers to bracket their assumptions. The significance for nurses of the wider study from which our example is taken is then described. Finally it is argued that despite the methodological difficulty described, a phenomenological perspective based on the philosophy of Husserl can point nurses in the direction of meeting the human needs of their patients.

  17. The aetiology of community associated pneumonia in children in Nanjing, China and aetiological patterns associated with age and season. (United States)

    Chen, Keping; Jia, Runqing; Li, Li; Yang, Chuankun; Shi, Yan


    Viral and atypical bacterial pathogens play an important role in respiratory tract infection. Using the Pneumoslide IgM test, the presented study explored the aetiology of community-acquired pneumonia and investigated further whether there was an association between age or season and aetiological organisms. Serum samples, taken between August 2011 and August 2013, from patients with CAP were tested with the Pneumoslide IgM kit. The Pneumoslide IgM technology can simultaneously diagnose 9 viral and atypical bacterial pathogens: Legionella pneumophila serogroup 1 (LP1), Mycoplasma pneumoniae (MP), Coxiella burnetii (COX), Chlamydophila pneumonia (CP), Adenovirus (ADV), Respiratory syncytial virus (RSV), Influenza A (INFA), Influenza B (INFB), Parainfluenza 1, 2 and 3 (PIVs). The data was analyzed by using Statistical Package for the Social Sciences for Windows (SPSS, version 11.0). Of a total of 1204 serum samples tested, 624 samples were positive. M. pneumoniae was the dominant pathogen, with INFB, PIVs, and RSV ranking second to fourth, respectively. The positive percentages of MP, INFB, PIVs and RSV were found to be associated with age, especially MP, INFB and PIVs. The positive percentages of MP, PIVs and RSV were also found to be associated with season. The positive percentage of MP in autumn was the highest. The positive percentages of LP1 in August and September, ADV in June and INFB in March were relatively higher than that in other months. The results show there were 4 main viral and atypical bacterial pathogens causing CAP in our study. Some pathogens were found to be associated with age and season. M. pneumoniae was the most predominant pathogen among these 9 pathogens. It is necessary to take preventative measures in order to prevent the spread of these pathogens in susceptible age groups during peak season.

  18. Suspension of Phenomenological Judgement of Scientific Naivety

    Directory of Open Access Journals (Sweden)

    Janko M. Lozar


    Full Text Available The article addresses the negative judgements on natural sciences, however persistent and frequent they may be, found scattered in the philosophical texts of the two founding fathers of phenomenology, Edmund Husserl and Martin Heidegger. It first presents these harsh views and then, by assuming the phenomenological method, advocated by both philosophers, endeavours to suspend these judgements in favour of a phenomenologically more adequate description of the scientific comportment, trying to do justice to its non-philosophical excellence. The basic claim of the treatise is that Husserl’s and Heidegger’s criticisms should only be understood in the defensive sense of procuring a firm and safe ground for theoretical comportment, bios 'theoretikos'. Such an approach, however, begs for a phenomenological description of the intrinsic excellence of science, which might be phenomenologically most accurately understood as most rigorous practical comportment, as 'bios praktikos'.

  19. Prevalence and correlates of auditory vocal hallucinations in middle childhood

    NARCIS (Netherlands)

    Bartels-Velthuis, A.A.; Jenner, J.A.; van de Willige, G.; van Os, J.; Wiersma, D.

    Background Hearing voices occurs in middle childhood, but little is known about prevalence, aetiology and immediate consequences. Aims To investigate prevalence, developmental risk factors and behavioural correlates of auditory vocal hallucinations in 7- and 8-year-olds. Method Auditory vocal

  20. Observation and phenomenology of glueballs

    Energy Technology Data Exchange (ETDEWEB)

    Lindenbaum, S.J.


    The experimental evidence and the relevant phenomenology of glueballs are reviewed. The opinion is expressed that the glueball resonance explanation is the only viable one for the data on g/sub T/, g/sub T/sup 1//, and g/sub T/sup 11//. It is shown that alternative explanations are either incorrect, or do not fit the data, or both, leading to the conclusion that these states are probably produced by glueballs. The OZI rule is explained. Glueball masses and width are considered. Some conclusions are drawn regarding an OZI suppressed reaction ..pi../sup -/p ..-->.. phi phi n. Glueball candidates from the J/psi radiative decay are discussed. 44 refs., 16 figs. (LEW)

  1. Observation and phenomenology of glueballs

    International Nuclear Information System (INIS)

    Lindenbaum, S.J.


    The experimental evidence and the relevant phenomenology of glueballs are reviewed. The opinion is expressed that the glueball resonance explanation is the only viable one for the data on g/sub T/, g/sub T 1 /, and g/sub T 11 /. It is shown that alternative explanations are either incorrect, or do not fit the data, or both, leading to the conclusion that these states are probably produced by glueballs. The OZI rule is explained. Glueball masses and width are considered. Some conclusions are drawn regarding an OZI suppressed reaction π - p → phi phi n. Glueball candidates from the J/psi radiative decay are discussed. 44 refs., 16 figs

  2. Astroparticle physics theory and phenomenology

    CERN Document Server

    Sigl, Günter


    This books aims at giving an overview over theoretical and phenomenological aspects of particle astrophysics and particle cosmology. To be of interest for both students and researchers in neighboring fields of physics, it keeps a balance between well established foundations that will not significantly change in the future and a more in-depth treatment of selected subfields in which significant new developments have been taking place recently. These include high energy particle astrophysics, such as cosmic high energy neutrinos, the interplay between detection techniques of dark matter in the laboratory and in high energy cosmic radiation, axion-like particles, and relics of the early Universe such as primordial magnetic fields and gravitational waves. It also contains exercises and thus will be suitable for both introductory and advanced courses in astroparticle physics.

  3. Phenomenology of large Nc QCD

    International Nuclear Information System (INIS)

    Richard Lebed


    These lectures are designed to introduce the methods and results of large N c QCD in a presentation intended for nuclear and particle physicists alike. Beginning with definitions and motivations of the approach, they demonstrate that all quark and gluon Feynman diagrams are organized into classes based on powers of 1/N c . They then show that this result can be translated into definite statements about mesons and baryons containing arbitrary numbers of constituents. In the mesons, numerous well-known phenomenological properties follow as immediate consequences of simply counting powers of N c , while for the baryons, quantitative large N c analyses of masses and other properties are seen to agree with experiment, even when ''large'' N c is set equal to its observed value of 3. Large N c reasoning is also used to explain some simple features of nuclear interactions

  4. Quantum groups in hadron phenomenology

    International Nuclear Information System (INIS)

    Gavrilik, A.M.


    We show that application of quantum unitary groups, in place of ordinary flavor SU(n f ), to such static aspects of hadron phenomenology as hadron masses and mass formulas is indeed fruitful. So-called q-deformed mass formulas are given for octet baryons 1/2 + and decuplet baryons 3/2 + , as well as for the case of vector mesons 1 - involving heavy flavors. For deformation parameter q, rigid fixation of values is used. New mass sum rules of remarkable accuracy are presented. As shown in decuplet case, the approach accounts for effects highly nonlinear in SU(3)-breaking. Topological implication (possible connection with knots) for singlet vector mesons and the relation q ↔ Θ c (Cabibbo angle) in case of baryons are considered

  5. Phenomenology of magnetospheric radio emissions (United States)

    Carr, T. D.; Desch, M. D.; Alexander, J. K.


    Jupiter has now been observed over 24 octaves of the radio spectrum, from about 0.01 MHz to 300,000 MHz. Its radio emissions fill the entire spectral region where interplanetary electromagnetic propagation is possible at wavelengths longer than infrared. Three distinct types of radiation are responsible for this radio spectrum. Thermal emission from the atmosphere accounts for virtually all the radiation at the high frequency end. Synchrotron emission from the trapped high-energy particle belt deep within the inner magnetosphere is the dominant spectral component from about 4000 to 40 MHz. The third class of radiation consists of several distinct components of sporadic low frequency emission below 40 MHz. The decimeter wavelength emission is considered, taking into account the discovery of synchrotron emission, radiation by high-energy electrons in a magnetic field, and the present status of Jovian synchrotron phenomenology. Attention is also given to the decameter and hectometer wavelength emission, and emissions at kilometric wavelengths.

  6. Cell phenomenology: The first phenomenon. (United States)

    Pattee, H H


    As a broad academic discipline phenomenology may be summarized as the study from a first person point of view of what appears to subjective human conscious experience. As a historical philosophical movement phenomenology was often motivated by the belief that subjective human experience is the proper foundation of all philosophy. I explore phenomena from a broader evolutionary and physical point of view. I consider a phenomenon as the subjective consequence of a physical interaction with an individual organism. In physical terms, a phenomenon requires some form of detection or measurement. What is detected is determined by the organism, and is potentially functional for the organism as a self or subject. The concept of function has meaning only for living organisms. The classical human mind-body problem is an ill-defined complicated case of the more general epistemic subject-object problem, which at the origin of life I reduce to the primitive symbol-matter problem. I argue that the first memory-based self-replicating unit, like a cell, is the most primitive case of a necessary symbol-matter distinction. The first phenomena, which include all forms or sensing, detection, and measurement, require a subject-object distinction, called the epistemic cut. It is only because of such a subject-object distinction that populations of individual subjects can selectively adapt to their environment by heritable variations. This basic evolutionary process requires distinguishing the individual's subjective phenomena from the objective events of inexorable physical laws. Copyright © 2015. Published by Elsevier Ltd.

  7. SLED phenomenology: curvature vs. volume

    International Nuclear Information System (INIS)

    Niedermann, Florian; Schneider, Robert


    We assess the question whether the SLED (Supersymmetric Large Extra Dimensions) model admits phenomenologically viable solutions with 4D maximal symmetry. We take into account a finite brane width and a scale invariance (SI) breaking dilaton-brane coupling, both of which should be included in a realistic setup. Provided that the brane tension and the microscopic size of the brane take generic values set by the fundamental bulk Planck scale, we find that either the 4D curvature or the size of the extra dimensions is unacceptably large. Since this result is independent of the dilaton-brane couplings, it provides the biggest challenge to the SLED program. In addition, to quantify its potential with respect to the cosmological constant problem, we infer the amount of tuning on model parameters required to obtain a sufficiently small 4D curvature. A first answer was recently given in, showing that 4D flat solutions are only ensured in the SI case by imposing a tuning relation, even if a brane-localized flux is included. In this companion paper, we find that the tuning can in fact be avoided for certain SI breaking brane-dilaton couplings, but only at the price of worsening the phenomenological problem. Our results are obtained by solving the full coupled Einstein-dilaton system in a completely consistent way. The brane width is implemented using a well-known ring regularization. In passing, we note that for the couplings considered here the results of (which only treated infinitely thin branes) are all consistently recovered in the thin brane limit, and how this can be reconciled with the concerns about their correctness, recently brought up in

  8. Chronic kidney disease of unknown aetiology in Sri Lanka: is cadmium a likely cause?

    Directory of Open Access Journals (Sweden)

    Peiris-John Roshini J


    Full Text Available Abstract Background The rising prevalence of chronic kidney disease (CKD and subsequent end stage renal failure necessitating renal replacement therapy has profound consequences for affected individuals and health care resources. This community based study was conducted to identify potential predictors of microalbuminuria in a randomly selected sample of adults from the North Central Province (NCP of Sri Lanka, where the burden of CKD is pronounced and the underlying cause still unknown. Methods Exposures to possible risk factors were determined in randomly recruited subjects (425 females and 461 males from selected areas of the NCP of Sri Lanka using an interviewer administered questionnaire. Sulphosalicylic acid and the Light Dependent Resister microalbumin gel filtration method was used for initial screening for microalbuminuria and reconfirmed by the Micral strip test. Results Microalbumnuria was detected in 6.1% of the females and 8.5% of the males. Smoking (p Conclusions Hypertension, diabetes mellitus, UTI, and smoking are known risk factors for microalbuminuria. The association between microalbuminuria and consumption of well water suggests an environmental aetiology to CKD in NCP. The causative agent is yet to be identified. Investigations for cadmium as a potential causative agent needs to be initiated.

  9. Understanding the aetiology and resolution of chronic otitis media from animal and human studies

    Directory of Open Access Journals (Sweden)

    Mahmood F. Bhutta


    Full Text Available Inflammation of the middle ear, known clinically as chronic otitis media, presents in different forms, such as chronic otitis media with effusion (COME; glue ear and chronic suppurative otitis media (CSOM. These are highly prevalent diseases, especially in childhood, and lead to significant morbidity worldwide. However, much remains unclear about this disease, including its aetiology, initiation and perpetuation, and the relative roles of mucosal and leukocyte biology, pathogens, and Eustachian tube function. Chronic otitis media is commonly modelled in mice but most existing models only partially mimic human disease and many are syndromic. Nevertheless, these models have provided insights into potential disease mechanisms, and have implicated altered immune signalling, mucociliary function and Eustachian tube function as potential predisposing mechanisms. Clinical studies of chronic otitis media have yet to implicate a particular molecular pathway or mechanism, and current human genetic studies are underpowered. We also do not fully understand how existing interventions, such as tympanic membrane repair, work, nor how chronic otitis media spontaneously resolves. This Clinical Puzzle article describes our current knowledge of chronic otitis media and the existing research models for this condition. It also identifies unanswered questions about its pathogenesis and treatment, with the goal of advancing our understanding of this disease to aid the development of novel therapeutic interventions.

  10. Understanding the aetiology and resolution of chronic otitis media from animal and human studies. (United States)

    Bhutta, Mahmood F; Thornton, Ruth B; Kirkham, Lea-Ann S; Kerschner, Joseph E; Cheeseman, Michael T


    Inflammation of the middle ear, known clinically as chronic otitis media, presents in different forms, such as chronic otitis media with effusion (COME; glue ear) and chronic suppurative otitis media (CSOM). These are highly prevalent diseases, especially in childhood, and lead to significant morbidity worldwide. However, much remains unclear about this disease, including its aetiology, initiation and perpetuation, and the relative roles of mucosal and leukocyte biology, pathogens, and Eustachian tube function. Chronic otitis media is commonly modelled in mice but most existing models only partially mimic human disease and many are syndromic. Nevertheless, these models have provided insights into potential disease mechanisms, and have implicated altered immune signalling, mucociliary function and Eustachian tube function as potential predisposing mechanisms. Clinical studies of chronic otitis media have yet to implicate a particular molecular pathway or mechanism, and current human genetic studies are underpowered. We also do not fully understand how existing interventions, such as tympanic membrane repair, work, nor how chronic otitis media spontaneously resolves. This Clinical Puzzle article describes our current knowledge of chronic otitis media and the existing research models for this condition. It also identifies unanswered questions about its pathogenesis and treatment, with the goal of advancing our understanding of this disease to aid the development of novel therapeutic interventions. © 2017. Published by The Company of Biologists Ltd.

  11. Understanding the aetiology and resolution of chronic otitis media from animal and human studies (United States)

    Thornton, Ruth B.; Kirkham, Lea-Ann S.; Kerschner, Joseph E.; Cheeseman, Michael T.


    ABSTRACT Inflammation of the middle ear, known clinically as chronic otitis media, presents in different forms, such as chronic otitis media with effusion (COME; glue ear) and chronic suppurative otitis media (CSOM). These are highly prevalent diseases, especially in childhood, and lead to significant morbidity worldwide. However, much remains unclear about this disease, including its aetiology, initiation and perpetuation, and the relative roles of mucosal and leukocyte biology, pathogens, and Eustachian tube function. Chronic otitis media is commonly modelled in mice but most existing models only partially mimic human disease and many are syndromic. Nevertheless, these models have provided insights into potential disease mechanisms, and have implicated altered immune signalling, mucociliary function and Eustachian tube function as potential predisposing mechanisms. Clinical studies of chronic otitis media have yet to implicate a particular molecular pathway or mechanism, and current human genetic studies are underpowered. We also do not fully understand how existing interventions, such as tympanic membrane repair, work, nor how chronic otitis media spontaneously resolves. This Clinical Puzzle article describes our current knowledge of chronic otitis media and the existing research models for this condition. It also identifies unanswered questions about its pathogenesis and treatment, with the goal of advancing our understanding of this disease to aid the development of novel therapeutic interventions. PMID:29125825

  12. Vaginal discharge: aetiological agents and evaluation of syndromic management in Lagos. (United States)

    Onyekonwu, C L; Olumide, Y M; Oresanya, F A; Onyekonwu, G C


    The WHO introduced the syndromic management to help in the control of STIs in resource-poor settings. This needs to be adapted to local settings taking into consideration the prevalence of the various organisms causing STIs. This has given rise to a need to validate the algorithm. The study aimed to correlate the syndromic management treatment algorithm for vaginal discharge with the aetiological diagnosis based on laboratory investigations. Specifically, the sensitivity, specificity and positive predictive values of the syndromic management against a gold standard laboratory diagnosis were evaluated. A total of 195 consecutive patients presenting to the study sites with vaginal discharge were enrolled in the study. Information on sociodemographic data was obtained with the aid of questionnaires. Samples were taken and examined for candida, trichomonas, bacterial vaginosis (BV), chlamydia and gonorrheal infections, after speculum and vaginal examinations. The sensitivity and positive predictive values (PPV) of the syndromic management in detecting vaginal infections performed better than corresponding values for cervicitis. The algorithm for cervicitis improved on addition of speculum examination (36% and 32.1% for sensitivity and PPV respectively). The study shows that the syndromic diagnosis for vaginal discharge fares better for vaginitis, especially with addition of speculum examination. The application of syndromic diagnosis for cervicitis resulted in omission of patients who had evidence of cervical infections by bacteriologic examination.

  13. Aetiology of obstructive azoospermia in Chinese infertility patients. (United States)

    Han, H; Liu, S; Zhou, X-G; Tian, L; Zhang, X-D


    To explore the aetiology of obstructive azoospermia (OA) in Chinese infertility patients, 133 OA patients was included in this study diagnosed and evaluated by one major specialist trained urological infertility. We retrospected the medical records to collect relative information. All of the patients had been underwent physical examination, ultrasound scan to the urogenital system, serum hormone tests, genetic tests and two separate semen analyses. The mean age of all 133 patients was 32.7 ± 6.8 years. A total of 266 reproductive tract units (two/patient) were classified into four categories: no causes (Idiopathic) for 74 units (27.8%), single cause for 173 units (65.0%), double causes for 17 units (6.4%) and triple causes for two units (0.8%). As to single cause of OA, there were four types: trauma for 0 unit (0%), infection for 125 units (47.0%), dysplasia for 11 units (4.1%) and surgeries for 37 units (13.9%). As to total cause of OA, there were five types: infection for 144 units (54.1%), orchitis for 51 units (19.2%), epididymitis for 54 units (20.3%), gonorrhoea for 28 units (10.5%) and inguinal hernia repair surgery for 18 units (6.8%). The most frequent cause of obstructive azoospermia was infection revealed in these Chinese infertility populations, followed by idiopathic reason. © 2015 Blackwell Verlag GmbH.

  14. Thromboembolic Conditions, Aetiology Diagnosis and Treatment in Dogs and Cats

    Directory of Open Access Journals (Sweden)

    Filip Konečný


    Full Text Available In veterinary medicine, thrombo-embolism (TE is an under-appreciated medical condition that requires immediate recognition. Since TE is multifactorial and its mode of presentation may vary, veterinarians face great difficulties in making a definitive diagnosis in a timely manner. In addition, most of the underlying conditions that give rise to TE are life-threatening and an aggressive diagnostic and therapeutic approach is required. Not only does the diagnosis and treatment of this condition require the collaboration of many specialties, the costs of therapy can be excessive with a high risk of recurrence. As such, owners have to be thoroughly informed before the therapy commences. While TE has been well-characterized in humans and is associated with significant morbidity and mortality, little information of similar quality is available in veterinary medicine. In addition, TE in animals is distinct from its human counterpart and we cannot simply adapt what is known from human clinical trials. With the promise of improvements in imaging modalities that improve our diagnostic capabilities, the window of opportunity to treat TE increases. This article focuses on aetiology, clinical presentation, diagnosis, and treatment of dogs and cats affected by TE.

  15. Comparison of radiological findings and microbial aetiology of childhood pneumonia

    International Nuclear Information System (INIS)

    Korppi, M.; Kiekara, O.; Kosma, T.H.; Soimakallio, S.


    61 children were treated in hospital from 1981 to 1982 because of both radiologically and microbiologically verified viral or bacterial pneumonia. The chest radiographs were interpreted by two radiologists, not familiar with the clinical data, on two occasions three years apart, and only those patients with a definite alveolar or interstitial pneumonia at both evaluations were included in the present analysis. In addition, all patients had viral, mixed viral-bacterial or bacterial infections diagnosed by viral or bacterial antibody or antigen assays. Viral infection alone was seen in 7, mixed viral-bacterial infection in 8 and bacterial infection alone in 12 of the 27 patients with alveolar pneumonia. The respective figures were 13, 13 and 8 for the 34 patients with interstitial pneumonia. C-reactive protein concentration was greater than 40 mg/l in 15 of the patients with alveolar and in 11 of the patients with interstitial pneumonia. Thus 74% of the patients with alveolar and 62% with interstitial pneumonia had bacterial infection, either alone or as a mixed viral-bacterial infection. The results suggest that the presence of an alveolar infiltrate in a chest radiograph is a specific but insensitive indicator of bacterial pneumonia. It is concluded that patients with alveolar pneumonia should be treated with antibiotics. In patients with interstitial pneumonia, however, both viral and bacterial aetiology are possible. In those, the decision concerning antibiotic treatment should be based on clinical and laboratory findings. 21 refs., 4 tabs

  16. Schizophrenia: metabolic aspects of aetiology, diagnosis and future treatment strategies. (United States)

    Harris, Laura W; Guest, Paul C; Wayland, Matthew T; Umrania, Yagnesh; Krishnamurthy, Divya; Rahmoune, Hassan; Bahn, Sabine


    Despite decades of research, the pathophysiology and aetiology of schizophrenia remains incompletely understood. The disorder is frequently accompanied by metabolic symptoms including dyslipidaemia, hyperinsulinaemia, type 2 diabetes and obesity. These symptoms are a common side effect of currently available antipsychotic medications. However, reports of metabolic dysfunction in schizophrenia predate the antipsychotic era and have also been observed in first onset patients prior to antipsychotic treatment. Here, we review the evidence for abnormalities in metabolism in schizophrenia patients, both in the central nervous system and periphery. Molecular analysis of post mortem brain tissue has pointed towards alterations in glucose metabolism and insulin signalling pathways, and blood-based molecular profiling analyses have demonstrated hyperinsulinaemia and abnormalities in secretion of insulin and co-released factors at first presentation of symptoms. Nonetheless, such features are not observed for all subjects with the disorder and not all individuals with such abnormalities suffer the symptoms of schizophrenia. One interpretation of these data is the presence of an underlying metabolic vulnerability in a subset of individuals which interacts with environmental or genetic factors to produce the overt symptoms of the disorder. Further investigation of metabolic aspects of schizophrenia may prove critical for diagnosis, improvement of existing treatment based on patient stratification/personalised medicine strategies and development of novel antipsychotic agents. Copyright © 2012 Elsevier Ltd. All rights reserved.

  17. Inflammatory aetiology of human myometrial activation tested using directed graphs.

    Directory of Open Access Journals (Sweden)


    Full Text Available THERE ARE THREE MAIN HYPOTHESES FOR THE ACTIVATION OF THE HUMAN UTERUS AT LABOUR: functional progesterone withdrawal, inflammatory stimulation, and oxytocin receptor activation. To test these alternatives we have taken information and data from the literature to develop causal pathway models for the activation of human myometrium. The data provided quantitative RT-PCR results on key genes from samples taken before and during labour. Principal component analysis showed that pre-labour samples form a homogenous group compared to those during labour. We therefore modelled the alternative causal pathways in non-labouring samples using directed graphs and statistically compared the likelihood of the different models using structural equations and D-separation approaches. Using the computer program LISREL, inflammatory activation as a primary event was highly consistent with the data (p = 0.925, progesterone withdrawal, as a primary event, is plausible (p = 0.499, yet comparatively unlikely, oxytocin receptor mediated initiation is less compatible with the data (p = 0.091. DGraph, a software program that creates directed graphs, produced similar results (p= 0.684, p= 0.280, and p = 0.04, respectively. This outcome supports an inflammatory aetiology for human labour. Our results demonstrate the value of directed graphs in determining the likelihood of causal relationships in biology in situations where experiments are not possible.

  18. Cracked tooth syndrome. Part 1: aetiology and diagnosis. (United States)

    Banerji, S; Mehta, S B; Millar, B J


    Symptomatic, incompletely fractured posterior teeth can be a great source of anxiety for both the dental patient and dental operator. For the latter, challenges associated with deriving an accurate diagnosis together with the efficient and time effective management of cases of cracked tooth syndrome are largely accountable for the aforementioned problem. The aim of this series of two articles is to provide the reader with an in-depth insight into this condition, through the undertaking of a comprehensive literature review of contemporarily available data. The first article will provide details relating to the background of cracked tooth syndrome including the epidemiology, patho-physiology, aetiology and diagnosis of the syndrome, together with a consideration of factors which may influence the prognostic outcome of teeth affected by incomplete, symptomatic fractures. The second article will focus on the immediate and intermediate management of cracked teeth, and also provide a detailed account of the application of both direct and indirect restorations and restorative techniques used respectively in the management of teeth affected by this complex syndrome.

  19. Local Aetiology and Pathways to Care in Malaria among the Ibibio of South-coastal Nigeria

    Directory of Open Access Journals (Sweden)

    A. S. Ajala


    Full Text Available There is a parallel between local and bio-medical perceptions of malaria among the Ibibio people of South-coastal Nigeria, as in many other societies of sub-Saharan Africa where malaria is endemic. Despite the fact that this accounts for resilience of the disease, earlier studies on malaria in Africa focused on causes, prevalence and socio-environmental factors. Local meanings of malaria and their influence on therapeutic choices have been largely ignored. This study examines local perceptions of malaria among the Ibibio and explains how attitudes are generated from indigenous meanings. It also examines how such attitudes inform a local aetiology of malaria. Similarly, our study examines how local meanings of, and attitudes towards malaria, set the pathway of care in malaria management among the Ibibio. Through qualitative and descriptive ethnography, Key Informant Interview (KII, Focus Group Discussion (FGD and the textual analysis of documents, our study seeks to establish that malaria is caused by parasites–protozoa. 83% of the respondents held that malaria is due to witchcraft, exposure to sunlight and eating of yellowish food items such as yellow maize, paw-paw, orange and red oil. These local perceptions are drawn from local conceptions which in turn encourage malaria patients to seek assistance outside modern health care facilities. This also discourages local communities from attending health education workshops that link malaria with germ theory and care. Treatment of malaria is thus mostly home-based where a wide variety of traditional remedies is practiced. Our study concludes that the lack of convergence between local knowledge-contents and bio-medical explanations account for a high prevalence rate and the lack of effective management. For proper management of malaria, there is a need to understand local knowledge and indigenous concepts in order to establish a convergence between bio-medical explanations and indigenous

  20. Phenomenology is not Phenomenalism. Is there such a thing as phenomenology of sport?


    Jan Halák; Ivo Jirásek; Mark Stephen Nesti


    Background: The application of the philosophical mode of investigation called "phenomenology" in the context of sport. Objective: The goal is to show how and why the phenomenological method is very often misused in sport-related research. Methods: Interpretation of the key texts, explanation of their meaning. Results: The confrontation of concrete sport-related texts with the original meaning of the key phenomenological notions shows mainly three types of misuse - the confusion of phenomenolo...

  1. Psychoanalysis--a phenomenology of language. (United States)

    Kupke, Christian


    It is often said that there is an unbridgeable gap between phenomenology and psychoanalysis. But this is only half the truth. Starting from Merleau-Ponty's proposal of an objectivistic and an idealistic divergence of Freud's enterprise the paper tries to reconstruct two possible movements: the objectivistic divergence of Husserl's enterprise as a phenomenological shift towards psychoanalysis and the idealistic divergence of Freud's enterprise as a psychoanalytical shift towards phenomenology. It is shown that this approach is possible on the field of language and semiotics where psychic life, as the essence of our subjectivity, may be rendered as a uniform phenomenon of an articulation in the world of signs. This thesis is elucidated at the end of the paper by discussing first (to the phenomenological side) a certain interpretation of the use of Husserl's reduction as a method of investigation in psychiatry and second (to the psychoanalytic side) the importance of Lacan's difference between repression and foreclosure for a psychopathological understanding of psychosis.

  2. Nucleon relativistic phenomenological and microscopic optical potential

    International Nuclear Information System (INIS)

    Shen Qingbiao; Feng Dachun; Zhuo Yizhong


    In this talk, both the phenomenological and microscopic nucleon relativistic optical potentials are presented. The global neutron relativistic phenomenological optical potential (RPOP) based on the available experimental data for various nuclei ranging from C to U with incident energies En=20-1000 MeV has been obtained through automatic search of the best parameters by computer. Then the nucleon relativistic microscopic optical potential (RMOP) is studied by utilizing effective lagrangian based on popular Walecka model. Through comparison between the theoretical results and experimental data we have shed some insight into both the RMOP and RPOP. We have concluded that both the phenomenological and microscopic relativistic optical potentials proposed here can be extensively used for intermediate energy nucleon data evaluation. Further improvement concerning how to combine the phenomenological potential with the microscopic one in order to reduce the number of free parameters appearing in RPOP is suggested. (author). 33 refs, 24 figs

  3. Phenomenological approaches in psychology and health sciences

    DEFF Research Database (Denmark)

    Davidsen, A.


    A whole family of qualitative methods is informed by phenomenological philosophy. When applying these methods, the material is analyzed using concepts from this philosophy to interrogate the findings and to enable greater theoretical analysis. However, the phenomenological approach represents...... different approaches, from pure description to those more informed by interpretation. Phenomenological philosophy developed from a discipline focusing on thorough descriptions, and only descriptions, toward a greater emphasis on interpretation being inherent in experience. An analogous development toward...... and Critical Narrative Analysis, methods which are theoretically founded in phenomenology. This methodological development and the inevitable contribution of interpretation are illustrated by a case from my own research about psychological interventions and the process of understanding in general practice....

  4. Indo-Pacific Journal of Phenomenology: Submissions

    African Journals Online (AJOL)

    , sexuality, cultural practice and personal preference. 2. The theoretical framework upon which submissions are founded should draw on the work of theoreticians from within Continental Philosophy and in particular phenomenology.

  5. The politics of phenomenological concepts in nursing. (United States)

    Holmes, C A


    This paper challenges those nurses who champion Heideggerian phenomenology, by outlining some of the possible political consequences of that philosophy. Some relationships between phenomenology and fascism are discussed, with special reference to anti-humanism and authenticity. Heidegger's commitment to Nazism is affirmed and, following the lead of other recent contributions to the debate, it is suggested that this was the likely, if not inevitable, result of his phenomenological philosophy. It is concluded that, because of its immanent fascism, Heideggerian phenomenology is at odds with the general value orientation publicly espoused by the nursing profession, and that this may render it not only unsuitable as a means of understanding and elaborating nursing knowledge, but also actively counter-productive to the conventional aspirations of nurses.

  6. Chronic pain epidemiology: from aetiology to public health

    National Research Council Canada - National Science Library

    Croft, Peter, Prof; Blyth, Fiona M; Windt, Danielle van der


    "Chronic pain is a major cause of distress, disability, and work loss, and it is becoming increasingly prevalent through the general move towards an ageing population, which impacts dramatically upon...

  7. Phenomenology of 1032 dark sectors

    International Nuclear Information System (INIS)

    Dvali, Gia; Redi, Michele


    We postulate an exact permutation symmetry acting on 10 32 standard model copies as the largest possible symmetry extension of the standard model. This setup automatically lowers the fundamental gravity cutoff down to TeV, and thus, accounts for the quantum stability of the weak scale. We study the phenomenology of this framework and show that below TeV energies the copies are well hidden, obeying all the existing observational bounds. Nevertheless, we identify a potential low energy window into the hidden world, the oscillation of the neutron into its dark copies. At the same time, proton decay can be suppressed by gauging the diagonal baryon number of the different copies. This framework offers an alternative approach to several particle physics questions. For example, we suggest a novel mechanism for generating naturally small neutrino masses that are suppressed by the number of neutrino species. The mirror copies of the standard model naturally house dark matter candidates. The general experimentally observable prediction of this scenario is an emergence of strong gravitational effects at the LHC. The low energy permutation symmetry powerfully constrains the form of this new gravitational physics and allows to make observational predictions, such as, production of micro black holes with very peculiar properties.

  8. Phenomenology of ELDER dark matter (United States)

    Kuflik, Eric; Perelstein, Maxim; Lorier, Nicolas Rey-Le; Tsai, Yu-Dai


    We explore the phenomenology of Elastically Decoupling Relic (ELDER) dark matter. ELDER is a thermal relic whose present density is determined primarily by the cross-section of its elastic scattering off Standard Model (SM) particles. Assuming that this scattering is mediated by a kinetically mixed dark photon, we argue that the ELDER scenario makes robust predictions for electron-recoil direct-detection experiments, as well as for dark photon searches. These predictions are independent of the details of interactions within the dark sector. Together with the closely related Strongly-Interacting Massive Particle (SIMP) scenario, the ELDER predictions provide a physically motivated, well-defined target region, which will be almost entirely accessible to the next generation of searches for sub-GeV dark matter and dark photons. We provide useful analytic approximations for various quantities of interest in the ELDER scenario, and discuss two simple renormalizable toy models which incorporate the required strong number-changing interactions among the ELDERs, as well as explicitly implement the coupling to electrons via the dark photon portal.

  9. Deuteron stripping reactions using dirac phenomenology (United States)

    Hawk, E. A.; McNeil, J. A.


    In this work deuteron stripping reactions are studied using the distorted wave born approximation employing dirac phenomenological potentials. In 1982 Shepard and Rost performed zero-range dirac phenomenological stripping calculations and found a dramatic reduction in the predicted cross sections when compared with similar nonrelativistic calculations. We extend the earlier work by including full finite range effects as well as the deuteron's internal D-state. Results will be compared with traditional nonrelativistic approaches and experimental data at low energy.

  10. Ethics in Husserl’s Phenomenology


    Hasan FathZadeh


    Starting with the ego's consciousness and emphasizing on staying at this realm, Husserl is accused of ignoring the absolute alterity of the other and reducing it to the presence of consciousness. By reducing the other he misses ethics and so embeds the violence at the heart of phenomenological discourse. Here we discuss on this criticism and then we try to defend Husserl against it. By putting phenomenology in its eidetic realm, we will try to answer these criticisms.

  11. Hadron mass scaling in Regge phenomenology

    International Nuclear Information System (INIS)

    Burakovsky, L.


    The authors show that Regge phenomenology is consistent with the only scaling law for the hadron masses, M * /M = (α'/α' * ) 1/2 , where asterisk indicates a finite-temperature quantity. Phenomenological models further suggest the following expression of the above scaling in terms of the temperature-dependent gluon condensate: M * /M = (α'/α' * ) 1/2 ( μν α > * / αμν >) 1/4

  12. On the Phenomenological Approach to Grammar

    Directory of Open Access Journals (Sweden)

    Volodymyr Shyrokov


    Full Text Available On the Phenomenological Approach to Grammar Phenomenological foundations for grammar description of the natural language are under considerations. The picture of language world based on the factorization of communication and cognitivity is proposed. The problem of observability-unobservability in linguistics is discussed. The concept of the states of language units is formulated both with its interpretation in the formal definition of the noun's case. System analysis of the complexity in cognitive processes is considered.

  13. On the Phenomenological Approach to Grammar


    Volodymyr Shyrokov; Igor Shevchenko


    On the Phenomenological Approach to Grammar Phenomenological foundations for grammar description of the natural language are under considerations. The picture of language world based on the factorization of communication and cognitivity is proposed. The problem of observability-unobservability in linguistics is discussed. The concept of the states of language units is formulated both with its interpretation in the formal definition of the noun's case. System analysis of the complexity in ...

  14. Orbital cellulitis in Scotland: current incidence, aetiology, management and outcomes. (United States)

    Murphy, C; Livingstone, I; Foot, B; Murgatroyd, H; MacEwen, C J


    Orbital cellulitis is a potentially blinding and life-threatening condition. There are little published data on the incidence of orbital cellulitis and little is known about the differences between children and adults affected. The purpose of this study was to identify the incidence, aetiology, management and outcome of orbital cellulitis in children and adults in Scotland. This study was a 1-year prospective observational study using the Scottish Ophthalmic Surveillance Unit reporting system among Scottish ophthalmologists. The response rate from ophthalmologists was 66.4%. There were 15 children and 5 adults reported giving an incidence of 1.6 per 100 000 and 0.1 per 100 000 in children and adults, respectively. 47% of children had a preceding upper respiratory tract infection with 87% having radiological evidence of sinus disease. Within the adult group, there was preceding immunosuppression and trauma. Streptococcus (66%) and Haemophilus (46%) species were the most commonly isolated pathogens in children. Respiratory pathogens were less predictable in adults. All patients were treated with intravenous antibiotics. All children with orbital and subperiosteal abscesses had surgery; one adult with orbital abscess did not have surgery. There were two cases of series morbidity: one intracranial spread of infection and one evisceration. The incidence of orbital cellulitis is higher in children than in adults. In children, it commonly follows upper respiratory infection and sinus disease; however, in adults, preceding illness and trauma are more common. Respiratory pathogens are common in affected children. Intravenous antibiotics and surgical treatment of abscesses remain the preferred management. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to

  15. Binocular diplopia in a tertiary hospital: Aetiology, diagnosis and treatment. (United States)

    Merino, P; Fuentes, D; Gómez de Liaño, P; Ordóñez, M A


    To study the causes, diagnosis and treatment in a case series of binocular diplopia. A retrospective chart review was performed on patients seen in the Diplopia Unit of a tertiary centre during a one-year period. Diplopia was classified as: acute≤1 month since onset; subacute (1-6 months); and chronic (>6 months). Resolution of diplopia was classified as: spontaneous if it disappeared without treatment, partial if the course was intermittent, and non-spontaneous if treatment was required. It was considered a good outcome when diplopia disappeared completely (with or without treatment), or when diplopia was intermittent without significantly affecting the quality of life. A total of 60 cases were included. The mean age was 58.65 years (60% female). An acute or subacute presentation was observed in 60% of the patients. The mean onset of diplopia was 82.97 weeks. The most frequent aetiology was ischaemic (45%). The most frequent diagnosis was sixth nerve palsy (38.3%), followed by decompensated strabismus (30%). Neuroimaging showed structural lesions in 17.7% of the patients. There was a spontaneous resolution in 28.3% of the cases, and there was a good outcome with disappearance of the diplopia in 53.3% at the end of the study. The most frequent causes of binocular diplopia were cranial nerve palsies, especially the sixth cranial nerve, followed by decompensated strabismus. Structural lesions in imaging tests were more than expected. Only one third of patients had a spontaneous resolution, and half of them did not have a good outcome despite of treatment. Copyright © 2017 Sociedad Española de Oftalmología. Publicado por Elsevier España, S.L.U. All rights reserved.

  16. Phenomenology and its application in medicine. (United States)

    Carel, Havi


    Phenomenology is a useful methodology for describing and ordering experience. As such, phenomenology can be specifically applied to the first person experience of illness in order to illuminate this experience and enable health care providers to enhance their understanding of it. However, this approach has been underutilized in the philosophy of medicine as well as in medical training and practice. This paper demonstrates the usefulness of phenomenology to clinical medicine. In order to describe the experience of illness, we need a phenomenological approach that gives the body a central role and acknowledges the primacy of perception. I present such a phenomenological method and show how it could usefully illuminate the experience of illness through a set of concepts taken from Merleau-Ponty. His distinction between the biological body and the body as lived, analysis of the habitual body, and the notions of motor intentionality and intentional arc are used to capture the experience of illness. I then discuss the applications this approach could have in medicine. These include narrowing the gap between objective assessments of well-being in illness and subjective experiences which are varied and diverse; developing a more attuned dialogue between physicians and patients based on a thick understanding of illness; developing research methods that are informed by phenomenology and thus go beyond existing qualitative methods; and providing medical staff with a concrete understanding of the impact of illness on the life-world of patients.

  17. Acute colonic pseudo-obstruction: A systematic review of aetiology and mechanisms (United States)

    Wells, Cameron I; O’Grady, Gregory; Bissett, Ian P


    AIM To critically review the literature addressing the definition, epidemiology, aetiology and pathophysiology of acute colonic pseudo-obstruction (ACPO). METHODS A systematic search was performed to identify articles investigating the aetiology and pathophysiology of ACPO. A narrative synthesis of the evidence was undertaken. RESULTS No consistent approach to the definition or reporting of ACPO has been developed, which has led to overlapping investigation with other conditions. A vast array of risk factors has been identified, supporting a multifactorial aetiology. The pathophysiological mechanisms remain unclear, but are likely related to altered autonomic regulation of colonic motility, in the setting of other predisposing factors. CONCLUSION Future research should aim to establish a clear and consistent definition of ACPO, and elucidate the pathophysiological mechanisms leading to altered colonic function. An improved understanding of the aetiology of ACPO may facilitate the development of targeted strategies for its prevention and treatment. PMID:28852322

  18. Conducting phenomenological research: Rationalising the methods and rigour of the Phenomenology of Practice. (United States)

    Errasti-Ibarrondo, Begoña; Jordán-Sierra, José Antonio; Díez-Del-Corral, Mercedes P; Arantzamendi, María


    To offer a complete outlook in a readable easy way of van Manen's hermeneutic-phenomenological method to nurses interested in undertaking phenomenological research. Phenomenology, as research methodology, involves a certain degree of complexity. It is difficult to identify a single article or author which sets out the didactic guidelines that specifically guide research of this kind. In this context, the theoretical-practical view of Max van Manen's Phenomenology of Practice may be seen as a rigorous guide and directive on which researchers may find support to undertake phenomenological research. Discussion paper. This discussion paper is based on our own experiences and supported by literature and theory. Our central sources of data have been the books and writings of Max van Manen and his website "Phenomenologyonline". The principal methods of the hermeneutic-phenomenological method are addressed and explained providing an enriching overview of phenomenology of practice. A proposal is made for the way the suggestions made by van Manen might be organised for use with the methods involved in Phenomenology of Practice: Social sciences, philosophical and philological methods. Thereby, nurse researchers interested in conducting phenomenological research may find a global outlook and support to understand and conduct this type of inquiry which draws on the art. The approach in this article may help nurse scholars and researchers reach an overall, encompassing perspective of the main methods and activities involved in doing phenomenological research. Nurses interested in doing phenomenology of practice are expected to commit with reflection and writing. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  19. Bruxism threshold: an explanation for successful treatment of the multifactorial aetiology of bruxism. (United States)

    Nel, J C; Bester, S P; Snyman, W D


    Many authors claim successful treatment of bruxism by various treatment modalities. This paper presents a review of the nature of bruxism, the multifactorial aetiology of bruxism and a discussion of successful treatment of bruxism by various treatment modalities. The aim of this paper is to provide an explanation for successful treatment of bruxism on the basis of decreasing or eliminating any one or more of the aetiological stimuli to a combined level below the bruxism threshold.

  20. The aetiology of acute and chronic pancreatitis over time in a hospital in Copenhagen

    DEFF Research Database (Denmark)

    Nøjgaard, Camilla; Bendtsen, Flemming; Matzen, Peter


    The change in aetiology over time of acute and chronic pancreatitis has been sparsely described, as has also the validity of the diagnostic codes. The aim of the study was 1) to clarify whether the aetiology of acute and chronic pancreatitis changed during the period 1983-2005, and 2) to validate...... the diagnostic codes over time for acute and chronic pancreatitis registered in the Danish National Patient Registry (NPR) in the same period....



    M. Amarendra; Garuda Rama; C. Rohit Kiran; DVRB Raju


    BACKGROUND Respiratory distress is a common problem encountered within the first 48-72 hours of life. It is one of the commonest cause of admission to NICU. So, it is very important to know the aetiology and risk factors associated with development of respiratory distress to provide better management. The aim of the study is to study the aetiology of respiratory distress and the risk factors associated with development of respiratory distress in term newborns. MATERIALS ...

  2. Phenomenology of modern education quality

    Directory of Open Access Journals (Sweden)

    Natalya G. Kulikova


    Full Text Available The national priority question of education quality is considered in the article at the level of an in-depth – existential – function of the educational system, where the former arises. In that case, education appears not only as a social organism, but a fundamental form of understanding existence and self-realization of a person as a self-organized space and biosocial system in terms of an integral educational result. The mechanisms and effects of formal development logic become clear from such research perspective namely, that changes into philosophy of education in the shape of a single-dimensional methodological imperative and provides for an inconsistency of educational practice, achievement of some pedagogical aims at the expense and to the disadvantage of others. The limited nature of pedagogical thinking is not simply fixed in the paradoxes of human development as an individual and organism, but is considered as the main obstacle in the way of evolution of the Human-Nature-Society global system. The phenomenological comprehension of education problems supposes coming into the space of a spiritual idea, funding the process of searching for quality at different levels of human life and activities from within, which characterizes the topicality of the given article. The aim of the scientific research is to analyze factors limiting the process of modern human development, and to ground the necessity of the fundamental updating of the education model in the noospheric scientific paradigm. Theoretical methods of research are used in the paper: analysis of scientific literature, system analysis, analogy, systematization, and generalization. The research results are represented in the categories of education philosophy and focus the reader’s attention mainly on its critical-reflexive function. Elimination of the subject of education is considered as a logical result of phenomenological reduction of thinking that loses a higher level of

  3. Phenomenology and qualitative research: combining the transcendetal orientation of phenomenology with the diversities of lived experience

    DEFF Research Database (Denmark)

    Ravn, Susanne

    In different ways philosophers have emphasized that phenomenology aims at accounting for our capacity for being conscious – for example by aiming at describing the structure of subjective experiences. Accordingly, phenomenology involves a transcendental orientation. In the domain of qualitative r...... of dancing, martial arts and elite sports....

  4. Paranasal sinusitis in the aetiology of orbital cellulitis | Ubah ...

    African Journals Online (AJOL)

    Aim: The purpose of this study was to assess the prevalence of paranasal sinusitis as a cause of orbital cellulitis and to identify the commonest sinus(es) involved in our setting. Methods: A retrospective review of the case notes of 47 patients with orbital cellulitis admitted into the ophthalmic ward of the University College ...

  5. Aetiology and antenatal diagnosis of spina bifida | Fieggen | South ...

    African Journals Online (AJOL)

    Spinal neural tube defects (NTDs) result from failure of neural tube closure that normally occurs at 15 - 28 days after conception. Birth prevalence figures for spina bifida vary, but on average are around 0.1%. There are no recent figures for South Africa, but previous studies have shown an incidence of 0.77 - 6.1/1 000 live ...

  6. Aetiology of low back pain in Mulago Hospital, Uganda | Galukande ...

    African Journals Online (AJOL)

    Background: Low back pain exists in epidemic proportions in the western world and is on the increase. Its cause is mostly nonspecific. Not much is known about it in the developing world because the data is scanty. This study was set out to investigate the possible causes of low back pain and prevalence. Objective: To ...

  7. An overview of interpretive phenomenology as a research methodology. (United States)

    Tuohy, Dympna; Cooney, Adeline; Dowling, Maura; Murphy, Kathy; Sixsmith, Jane


    To provide an overview of interpretive phenomenology. Phenomenology is a philosophy and a research approach. As a research approach, it is used extensively in nursing and 'interpretive' phenomenology is becoming increasingly popular. Online and manual searches of relevant books and electronic databases were undertaken. Literature review on papers on phenomenology, research and nursing (written in English) was undertaken. A brief outline of the origins of the concept, and the influence of 'descriptive' phenomenology on the development of interpretive phenomenology is provided. Its aim, origins and philosophical basis, including the core concepts of dasein, fore-structure/pre-understanding, world view existential themes and the hermeneutic circle, are described and the influence of these concepts in phenomenological nursing research is illustrated. This paper will assist readers when deciding whether interpretive phenomenology is appropriate for their research projects. This paper adds to the discussion on interpretive phenomenology and helps inform readers of its use as a research methodology.

  8. The current dialogue between phenomenology and psychiatry: a problematic misunderstanding. (United States)

    Abettan, Camille


    A revival of the dialogue between phenomenology and psychiatry currently takes place in the best international journals of psychiatry. In this article, we analyse this revival and the role given to phenomenology in this context. Although this dialogue seems at first sight interesting, we show that it is problematic. It leads indeed to use phenomenology in a special way, transforming it into a discipline dealing with empirical facts, so that what is called "phenomenology" has finally nothing to do with phenomenology. This so-called phenomenology tallies however with what we have always called semiology. We try to explain the reasons why phenomenology is misused in that way. In our view, this transformation of phenomenology into an empirical and objectifying discipline is explained by the role attributed to phenomenology by contemporary authors, which is to solve the problems raised by the Diagnostic and Statistical Manual of Mental Disorders.

  9. Phenomenology as a resource for patients. (United States)

    Carel, Havi


    Patient support tools have drawn on a variety of disciplines, including psychotherapy, social psychology, and social care. One discipline that has not so far been used to support patients is philosophy. This paper proposes that a particular philosophical approach, phenomenology, could prove useful for patients, giving them tools to reflect on and expand their understanding of their illness. I present a framework for a resource that could help patients to philosophically examine their illness, its impact on their life, and its meaning. I explain the need for such a resource, provide philosophical grounding for it, and outline the epistemic and existential gains philosophy offers. Illness often begins as an intrusion on one's life but with time becomes a way of being. I argue that this transition impacts on core human features such as the experience of space and time, human abilities, and adaptability. It therefore requires philosophical analysis and response. The paper uses ideas from Husserl and Merleau-Ponty to present such a response in the form of a phenomenological toolkit for patients. The toolkit includes viewing illness as a form of phenomenological reduction, thematizing illness, and examining illness as altering the ill person's being in the world. I suggest that this toolkit could be offered to patients as a workshop, using phenomenological concepts, texts, and film clips to reflect on illness. I conclude by arguing that examining illness as a limit case of embodied existence deepens our understanding of phenomenology.

  10. Husserlian phenomenology and nursing in a unitary-transformative paradigm

    DEFF Research Database (Denmark)

    Hall, Elisabeth


    . The phenomenological methodology according to Spiegelberg is described, and exemplified through the author's ongoing study. Different critiques of phenomenology and phenomenological reports are mentioned, and the phenomenological description is illustrated as the metaphor «using a handful of colors». The metaphor...... is used to give phenomenological researchers and readers an expanding reality picturing, including memories and hopes and not only a reality of the five senses. It is concluded that phenomenology as a world view and methodology can contribute to nursing research and strengthen the identity of nursing...

  11. The Use of Phenomenology in Nursing Education: An Integrative Review. (United States)

    Derico, Sherika P

    The purpose of this integrative review was to synthesize research to address two questions about phenomenology in nursing education: How has Husserlian phenomenology been used in nursing education? What is the importance of Husserlian phenomenology in nursing education? Phenomenology is utilized in nursing education to explore the experiences of faculty and students. Whittemore and Knafl's integrative method guided the analysis of the research. Nine articles meeting inclusion criteria were reviewed. Studies addressed faculty student experiences. The reviewed research revealed that phenomenology is used in nursing education to understand, identify, describe, and explore various phenomena. New knowledge gained from this integrative review about phenomenology is beneficial to nursing education.

  12. Neutron relativistic phenomenological and microscopic optical potential

    International Nuclear Information System (INIS)

    Shen Qing-biao; Feng Da-chun; Zhuo Yi-zhong


    In this paper, both the phenomenological and microscopic neutron relativistic optical potentials are presented. The global neutron relativistic phenomenological optical potential (RPOP) based on the available experimental data for various nuclei ranging from C to U with incident energies E n =20--1000 MeV has been obtained through an automatic search of the best parameters by computer. Then the nucleon relativistic microscopic optical potential (RMOP) is studied by utilizing the effective Lagrangian based on the popular Walecka model. Through comparison between the theoretical results and experimental data we shed some insight into both the RMOP and RPOP. Further improvement concerning how to combine the phenomenological potential with the microscopic one in order to reduce the number of free parameters appearing in the RPOP is suggested

  13. Heidegger’s phenomenology of the invisible

    Directory of Open Access Journals (Sweden)

    Andrzej SERAFIN


    Full Text Available Martin Heidegger has retrospectively characterized his philosophy as “phenomenology of the invisible”. This paradoxical formula suggests that the aim of his thinking was to examine the origin of the phenomena. Furthermore, Heidegger has also stated that his philosophy is ultimately motivated by a theological interest, namely the question of God’s absence. Following the guiding thread of those remarks, this essay analyzes the essential traits of Heidegger’s thought by interpreting them as an attempt to develop a phenomenology of the invisible. Heidegger’s attitude towards physics and metaphysics, his theory of truth, his reading of Aristotle, his concept of Dasein, his understanding of nothingness are all situated within the problematic context of the relation between the invisible and the revealed. Heidegger’s thought is thereby posited at the point of intersection of phenomenology, ontology, and theology.

  14. Some thoughts on phenomenology and medicine. (United States)

    Kottow, Miguel


    Phenomenology in medicine's main contribution is to present a first-person narrative of illness, in an effort to aid medicine in reaching an accurate disease diagnosis and establishing a personal relationship with patients whose lived experience changes dramatically when severe disease and disabling condition is confirmed. Once disease is diagnosed, the lived experience of illness is reconstructed into a living-with-disease narrative that medicine's biological approach has widely neglected. Key concepts like health, sickness, illness, disease and the clinical encounter are being diversely and ambiguously used, leading to distortions in socio-medical practices such as medicalization, pharmaceuticalization, emphasis on surveillance medicine. Current definitions of these concepts as employed in phenomenology of medicine are revised, concluding that more stringent semantics ought to reinforce an empirical phenomenological or postphenomenological approach.

  15. Kriegel on the Phenomenology of Action. (United States)

    Shepherd, Joshua


    I focus on Uriah Kriegel's account of conative phenomenology. I agree with Kriegel's argument that some conative phenomenology is primitive in that some conative phenomenal properties cannot be reduced to another kind of property (e.g., perceptual or cognitive). I disagree, however, with Kriegel's specific characterization of the properties in question. Kriegel argues that the experience of deciding-and-then-trying is the core of conative phenomenology. I argue, however, that the experiences of trying and acting better occupy this place. Further, I suggest that the attitudinal component of the experiences of trying and acting is not, as Kriegel suggests, best characterized in terms of commitment to the rightness or goodness of the objects of experience. Rather, I argue that the attitudinal component is best characterized in imperatival terms.

  16. Fundamental phenomenological categories of garden and landscape

    Directory of Open Access Journals (Sweden)

    Marie Zgarbová


    Full Text Available The current scientific methods describing gardens and landscapes all over the world are not always sufficient for the purpose of deep understanding of specific and close relations between landscape/garden and its inhabitants/visitors. A new dimension of qualitative investigation of these phenomena and relations between humans and the environment, as distinguished from the common mechanistic methods, has to be acquired. While a systematic anti-mechanistic research on the interaction of humans and living space is carried out especially in the United Kingdom and the United States, Continental Europe persist mechanistic in its core.In Continental Europe phenomenology as well as hermeneutics are regarded mostly as the particular areas of abstract philosophical studies that do not refer enough to practical sciences such as, for example, garden and landscape architecture. However, there are some especially transatlantic centres of applied phenomenological research. This article examines the phenomenological and hermeneutical approach as it might be used to explore the specific field of garden and landscape issues. In the first step, the nature of hermeneutics and phenomenology as compared to the common mechanistic scientific methods is discussed and the parallels between hermeneutics and phenomenology are outlined. Then, using the phenomenological method helps we give evidence on the fundamental categories of garden and landscape. These categories, in contrast to mechanistic constructions, represent garden and landscape as they are intimately experienced by humans. The focus of this research is both methodological (it is an effort to articulate a method alternative to the objectivity and abstraction of strict science, to be used in the field of garden and landscape architecture and related areas and hermeneutical (it is an effort to achieve a deeper and profound understanding of garden and landscape as the irreplaceable base for every responsible

  17. Gender differences in the phenomenology of bipolar disorder

    DEFF Research Database (Denmark)

    Kessing, Lars Vedel


    OBJECTIVES: To investigate gender differences in the phenomenology of episodes in bipolar disorder as according to ICD-10. METHODS: All patients who got a diagnosis of a manic episode/bipolar disorder in a period from 1994 to 2002 at the first outpatient treatment ever or at the first discharge...... from psychiatric hospitalization ever in Denmark were identified in a nationwide register. RESULTS: Totally, 682 outpatients and 1037 inpatients got a diagnosis of a manic episode/bipolar disorder at the first contact ever. Significantly more women were treated as outpatients than as inpatients. Women...... patients treated during hospitalization more women than men presented with mixed episodes. CONCLUSIONS: Besides differences in the prevalence of mixed episodes and comorbid substance abuse few gender differences are found among patients presenting with a manic episode/bipolar disorder at first contact...

  18. Phenomenology as research method or substantive metaphysics? An overview of phenomenology's uses in nursing. (United States)

    Earle, Vicki


    In exploring phenomenological literature, it is evident that the term 'phenomenology' holds rather different meanings depending upon the context. Phenomenology has been described as both a philosophical movement and an approach to human science research. The phenomenology of Husserl, Heidegger, Gadamer, and Merleau-Ponty was philosophical in nature and not intended to provide rules or procedures for conducting research. The Canadian social scientist, van Manen, however, introduced specific guidelines for conducting human science research, which is rooted in hermeneutic phenomenology and this particular method has been employed in professional disciplines such as education, nursing, clinical psychology, and law. The purpose of this paper is to explore the difference between the phenomenological method as described by van Manen and that of other philosophers such as Husserl, Heidegger, Gadamer, and Merleau-Ponty. In so doing, the author aims to address the blurred boundaries of phenomenology as a research method and as a philosophical movement and highlight the influence of these blurred boundaries on nursing knowledge development.

  19. Cervicitis aetiology and case definition: a study in Australian women attending sexually transmitted infection clinics. (United States)

    Lusk, M Josephine; Garden, Frances L; Rawlinson, William D; Naing, Zin W; Cumming, Robert G; Konecny, Pam


    Studies examining cervicitis aetiology and prevalence lack comparability due to varying criteria for cervicitis. We aimed to outline cervicitis associations and suggest a best case definition. A cross-sectional study of 558 women at three sexually transmitted infection clinics in Sydney, Australia, 2006-2010, examined pathogen and behavioural associations of cervicitis using three cervicitis definitions: 'microscopy' (>30 pmnl/hpf (polymorphonuclear leucocytes per high-powered field on cervical Gram stain)), 'cervical discharge' (yellow and/or mucopurulent cervical discharge) or 'micro+cervical discharge' (combined 'microscopy' and 'cervical discharge'). Chlamydia trachomatis (CT), Mycoplasma genitalium (MG), Trichomonas vaginalis (TV) and Neisseria gonorrhoeae (NG) had the strongest associations with cervicitis definitions 'micro+cervical discharge': CT adjusted prevalence ratio (APR)=2.13 (95% CI 1.38 to 3.30) p=0.0006, MG APR=2.21 (1.33 to 3.69) p=0.002, TV APR=2.37 (1.44 to 3.90) p=0.0007 NG PR=4.42 (3.79 to 5.15) pcervical discharge': CT APR=1.90 (1.25 to 2.89) p=0.003, MG APR=1.93 (1.17 to 3.19) p=0.011, TV APR=2.02 (1.24 to 3.31) p=0.005 NG PR=3.88 (3.36 to 4.48) pcervicitis risk: ('micro+cervical discharge') APR=0.69 (0.51 to 0.93) p=0.016. Combined population attributable risk % (PAR%) of these four pathogens was only 18.0% with a protective PAR% of condoms of 25.7%. Exposures not associated with cervicitis included bacterial vaginosis, Mycoplasma hominis, Ureaplasma urealyticum, herpes simplex virus 1&2, cytomegalovirus, Candida, age, smoking and hormonal contraception. Cervicitis was associated with CT, MG, TV and NG with combined PAR% of these pathogens only 18% in this setting, suggesting other factors are involved. Condoms significantly reduced cervicitis risk. Cervicitis definitions with best clinical utility and pathogen prediction were 'cervical discharge' and 'micro+cervical discharge'. Published by the BMJ Publishing Group Limited. For

  20. [An existential-phenomenological approach to consciousness]. (United States)

    Langle, A


    The human beings are characterized as subjects. Their essence is understood as Person. A treatment which does not consider the subjective and the Person would not correspond their essence. For a feeling and autonomous being, consciousness plays a role but cannot fully correspond the being a person. This has a therapeutic impact on the treatment of unconscious patients and gives the treatment a specific access. Some instructions for the therapeutic application of the phenomenological-existential concept and the phenomenological attitude towards unconscious or brain traumatized patients are given. The role of consciousness for being human is briefly reflected from an existential perspective.

  1. Towards a Relational Phenomenology of Violence. (United States)

    Staudigl, Michael

    This article elaborates a relational phenomenology of violence. Firstly, it explores the constitution of all sense in its intrinsic relation with our embodiment and intercorporality. Secondly, it shows how this relational conception of sense and constitution paves the path for an integrative understanding of the bodily and symbolic constituents of violence. Thirdly, the author addresses the overall consequences of these reflections, thereby identifying the main characteristics of a relational phenomenology of violence. In the final part, the paper provides an exemplification of the outlined conception with regard to a concrete phenomenon of violence, i.e., slapping, and a concluding reflection upon its overall significance for research on violence.

  2. Statistical turbulence theory and turbulence phenomenology (United States)

    Herring, J. R.


    The application of deductive turbulence theory for validity determination of turbulence phenomenology at the level of second-order, single-point moments is considered. Particular emphasis is placed on the phenomenological formula relating the dissipation to the turbulence energy and the Rotta-type formula for the return to isotropy. Methods which deal directly with most or all the scales of motion explicitly are reviewed briefly. The statistical theory of turbulence is presented as an expansion about randomness. Two concepts are involved: (1) a modeling of the turbulence as nearly multipoint Gaussian, and (2) a simultaneous introduction of a generalized eddy viscosity operator.

  3. Phenomenological realism, superconductivity and quantum mechanics

    International Nuclear Information System (INIS)

    Shomar, T.L.E.


    The central aim of this thesis is to present a new kind of realism that is driven not from the traditional realism/anti-realism debate but from the practice of physicists. The usual debate focuses on discussions about the truth of theories and their fit with nature, while the real practices of the scientists are forgotten. The position I shall defend is called 'phenomenological realism': theories are merely tools to construct other theories and models, including phenomenological models; phenomenological models are the vehicles of representation. The realist doctrine was recently undermined by the argument from the pessimistic meta-induction, also known as the argument from scientific revolutions. I argue that phenomenological realism is a new kind of scientific realism which can overcome the problem generated by the argument from scientific revolutions, and which depend on the scientific practice. The realist tried to overcome this problem by suggesting various types of theory dichotomy. I claim that different types of dichotomy presented by realists did not overcome the problem, these dichotomies cut through theory vertically. I argue for a different kind of dichotomy between high level theoretical abstractions and low-level theoretical representations. I claim that theoretical work in physics have two distinct types depending on the way they are built these are: theoretical models which built depending on a top-down approach and phenomenological models which are built depending on a bottom-up approach, this dichotomy cuts the division along a horizontal line between low and high level theory. I present two case studies. One from superconductivity where I contrast the BCS theory of superconductivity with the phenomenological model of Landau and Ginzburg. I show how in that field of physics the historical developments favoured phenomenological models over high-level theoretical abstraction. I show how the BCS theory of superconductivity was constructed, and why it

  4. Supersymmetry and supergravity: Phenomenology and grand unification

    International Nuclear Information System (INIS)

    Arnowitt, R.; Nath, P.


    A survey is given of supersymmetry and supergravity and their phenomenology. Some of the topics discussed are the basic ideas of global supersymmetry, the minimal supersymmetric Standard Model (MSSM) and its phenomenology, the basic ideas of local supersymmetry (supergravity), grand unification, supersymmetry breaking in supergravity grand unified models, radiative breaking of SU(2) x U(1), proton decay, cosmological constraints, and predictions of supergravity grand unified models. While the number of detailed derivations are necessarily limited, a sufficient number of results are given so that a reader can get a working knowledge of this field

  5. Digital Immigrant Teacher Perceptions of Social Media as It Influences the Affective and Cognitive Development of Students: A Phenomenological Study (United States)

    Williams, Robert Warren


    The purpose of this transcendental phenomenological study is to describe how digital immigrant teachers perceive the influence of social media on the affective and cognitive development of students at three high schools in Alabama. As the prevalence of social technologies is increasing, educators must understand how it is affecting students in…

  6. Prevalence of Urinary Tract Infections (UTI) in sexually active ...

    African Journals Online (AJOL)

    Aresearch to investigate the prevalence of urinary tract infections in sexually active women (18 – 41 years) from selected health care centres in Abakaliki was carried out. Attempt was made to fined out the number of treated cases, aetiologic agents and age range with highest incdence o urinary tract infections over the study ...

  7. Prevalence and Susceptibility Patterns of Clinical Isolates of ...

    African Journals Online (AJOL)

    The purpose of this study is to determine the prevalence of Escherichia coli as an aetiologic agent in bacterial infections and its antimicrobial susceptibility patterns to ciprofloxacin, ofloxacin, norfloxacin, perfloxacin, gentamycin and cotrimoxazole as a guide for empiric therapy. A retrospective study was carried out using a ...

  8. Prevalence of Aeromonas species and Escherichia coli in stool ...

    African Journals Online (AJOL)

    Background: Diarrhoea is one of the main causes of mortality and morbidity in childhood. Bacterial diarrhoea is a common disorder. Aeromonas species and Escherichia coli (E. coli) are some of the aetiological agents associated with diarrhoea in children. Objective: To determine the prevalence of Aeromonas species and ...

  9. “Higher than Actuality” - The Possibility of Phenomenology in ...

    African Journals Online (AJOL)

    possibility' to consider the methodological significance of Heidegger's conception of what is essential in phenomenology as inhering not "in its actuality as a philosophical 'movement'", but in the understanding of phenomenology "as a possibility".

  10. The role of supersymmetry phenomenology in particle physics

    International Nuclear Information System (INIS)

    Wells, James D.


    Supersymmetry phenomenology is an important component of particle physics today. I provide a definition of supersymmetry phenomenology, outline the scope of its activity, and argue its legitimacy. This essay derives from a presentation given at the 2000 SLAC Summer Institute

  11. Bottlenecks in domestic animal populations can facilitate the emergence of Trypanosoma cruzi, the aetiological agent of Chagas disease. (United States)

    Levy, Michael Z; Tustin, Aaron; Castillo-Neyra, Ricardo; Mabud, Tarub S; Levy, Katelyn; Barbu, Corentin M; Quispe-Machaca, Victor R; Ancca-Juarez, Jenny; Borrini-Mayori, Katty; Naquira-Velarde, Cesar; Ostfeld, Richard S


    Faeces-mediated transmission of Trypanosoma cruzi (the aetiological agent of Chagas disease) by triatomine insects is extremely inefficient. Still, the parasite emerges frequently, and has infected millions of people and domestic animals. We synthesize here the results of field and laboratory studies of T. cruzi transmission conducted in and around Arequipa, Peru. We document the repeated occurrence of large colonies of triatomine bugs (more than 1000) with very high infection prevalence (more than 85%). By inoculating guinea pigs, an important reservoir of T. cruzi in Peru, and feeding triatomine bugs on them weekly, we demonstrate that, while most animals quickly control parasitaemia, a subset of animals remains highly infectious to vectors for many months. However, we argue that the presence of these persistently infectious hosts is insufficient to explain the observed prevalence of T. cruzi in vector colonies. We posit that seasonal rains, leading to a fluctuation in the price of guinea pig food (alfalfa), leading to annual guinea pig roasts, leading to a concentration of vectors on a small subpopulation of animals maintained for reproduction, can propel T. cruzi through vector colonies and create a considerable force of infection for a pathogen whose transmission might otherwise fizzle out. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  12. Prevalence of obesity in Denmark

    DEFF Research Database (Denmark)

    Due, P; Heitmann, B L; Sørensen, T I A


    There has been a pronounced, distinctive increase of the prevalence of obesity within almost all age groups of the Danish population, during the last 25-30 years. The largest increase has been documented in studies based on objective data from total populations and the latest data show the increase...... will continue. The Danish studies show heterogeneity in the development of the obesity epidemic. A close association with birth cohorts indicates a need for further aetiological research, not only into behavioural factors, but also into early life factors that may explain some of this developmental pattern....

  13. The experience of watching dance: phenomenological-neuroscience duets


    Jola, C; Ehrenberg, S; Reynolds, D


    This paper discusses possible correspondences between neuroscientific findings and phenomenologically informed methodologies in the investigation of kinesthetic empathy in watching dance. Interest in phenomenology has recently increased in cognitive science (Gallagher and Zahavi 2008) and dance scholars have recently contributed important new insights into the use of phenomenology in dance studies (e.g. Legrand and Ravn (Phenomenology and the Cognitive Sciences 8(3):389–408, 2009); Parviainen...

  14. Sonography of gallstones and biliary dilatation without a visible aetiology: The infrequency of obstructing choledocholithiasis

    Energy Technology Data Exchange (ETDEWEB)

    Cabrera, O.; Van Sonnenberg, E.; Wittich, G.R.; Leopold, G.R.; Gosink, U.B.; Bowen, J.S.


    This paper describes 50 consecutive patients who sonographically had gallbladder stones and dilated bile ducts, but no visible aetiology for the dilatation. We reviewed these cases to determine the frequency of choledocholithiasis in this setting. Common duct stones caused obstruction in only 36% of these patients. Other aetiologies included strictures due to chronic pancreatitis or prior stone passage in 24% of the patients, and malignant obstruction in 16%. In 24% of the patients, no cause was found for biliary dilatation: common duct stones or obstructing tumours were excluded in the group. Since aetiologies other than stones are likely in a majority of cases, further preoperative workup (CT, percutaneous transhepatic cholangiography, ERCP) or intraoperative cholangiography (if the patient requires urgent cholecystectomy) is indicated. The additional studies should provide a diagnosis, help determine whether or not the common duct should be explored, or avoid unnecessary operation in case of incurable malignancy.

  15. Sonography of gallstones and biliary dilatation without a visible aetiology: The infrequency of obstructing choledocholithiasis

    International Nuclear Information System (INIS)

    Cabrera, O.; Van Sonnenberg, E.; Wittich, G.R.; Leopold, G.R.; Gosink, U.B.; Bowen, J.S.; California Univ., San Diego, La Jolla


    This paper describes 50 consecutive patients who sonographically had gallbladder stones and dilated bile ducts, but no visible aetiology for the dilatation. We reviewed these cases to determine the frequency of choledocholithiasis in this setting. Common duct stones caused obstruction in only 36% of these patients. Other aetiologies included strictures due to chronic pancreatitis or prior stone passage in 24% of the patients, and malignant obstruction in 16%. In 24% of the patients, no cause was found for biliary dilatation: common duct stones or obstructing tumours were excluded in the group. Since aetiologies other than stones are likely in a majority of cases, further preoperative workup (CT, percutaneous transhepatic cholangiography, ERCP) or intraoperative cholangiography (if the patient requires urgent cholecystectomy) is indicated. The additional studies should provide a diagnosis, help determine whether or not the common duct should be explored, or avoid unnecessary operation in case of incurable malignancy. (orig.)

  16. Indo-Pacific Journal of Phenomenology

    African Journals Online (AJOL)

    The Phenomenology Research Group is a circle of postgraduate scholars who have a range of research interests which cross a broad spectrum of areas including education, health, religion, business, tourism, counselling and psychology. The journal is published by NISC SA (IPJP on NISC) and has its own website online ...

  17. Dreaming Consciousness: A Contribution from Phenomenology

    Directory of Open Access Journals (Sweden)

    Nicola Zippel


    Full Text Available The central aim of this paper is to offer a historical reconstruction of phenomenological studies on dreaming and to put forward a draft for a phenomenological theory of the dream state. Prominent phenomenologists have offered an extremely valuable interpretation of the dream as an intentional process, stressing its relevance in understanding the complexity of the mental life of subject, the continuous interplay between reality and unreality, and the possibility of building parallel spheres of experience influencing the development of personal identity. Taking into consideration the main characteristics of dream experience emphasized by these scholars, in the final part of the paper I propose to elaborate a new phenomenology of dreaming, which should be able to offer a theoretical description of dream states. My sketched proposal is based on Eugen Fink’s notion of the dream as “presentification”. By combining the past and the present of phenomenological investigation, I aim at suggesting a philosophical framework to explain the intentional features of dreaming as Erlebnis.

  18. A Phenomenological Investigation of "Good" Supervision Events. (United States)

    Worthen, Vaughn; McNeill, Brian W.


    Explored the experience of "good" supervision events from the perspective of supervisees using a qualitative phenomenological research methodology. Eight intermediate-level to advanced-level trainees participated in a tape-recorded interview in which they described a recent good supervision experience, yielding transcripts that were subjected to a…

  19. Intentionality and Narrativity in Phenomenological Psychological ...

    African Journals Online (AJOL)

    Christopher R Stones


    Oct 2, 2014 ... to Vandevelde (2008): “on the hermeneutic side, narratives are an interpretive mediation, but, on the phenomenological side, they provide the meaning content or noema of what is so recounted” (p. 142). Hence, in reflecting on the meaning of the life stories told to researchers by participants, or in reflecting.

  20. Welcome to the phenomenological tradition! | Embree | South ...

    African Journals Online (AJOL)

    This essay was written on the basis of what I call a 'happy misunde rstanding', which is already conspicuous in the first paragraph below. Most misunderstandings have negative consequences. But in this case I was delighted to learn that I was mistaken in believing that phenomenology was just getting going in South Africa, ...

  1. Superstring phenomenology present-and-future perspective

    International Nuclear Information System (INIS)

    Faraggi, A.E.


    The objective of superstring phenomenology is to develop the models and methodology needed to connect quantitatively between Planck scale and electroweak scale experimental data. I review the present status of this endeavor with a focus on the three generation free fermionic models

  2. A phenomenological investigation of women's experience of ...

    African Journals Online (AJOL)

    Proceeding from a phenomenological perspective, the present study investigated the experiences of seven homeless women who had lived through childhood trauma and subsequent substance abuse, with specific focus on the recovery process experienced by each. Applying the analytical protocol of Giorgi (1985) to the ...

  3. Existential-Phenomenological Psychology: A Brief Introduction

    African Journals Online (AJOL)

    Book Review: Existential-Phenomenological Psychology: A Brief Introduction. G du Plessis. Abstract. No abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians ...

  4. Phenomenological approach to nuclear level densities

    International Nuclear Information System (INIS)

    Reffo, G.


    The topic of nuclear level densities is considered from the standpoint of applications. A phenomenological approach is described in which relevant parameters are derived from known experimental quantities. Parameter systematics have been determined which may be used for interpolation where experimental information is not available

  5. Humanising Forces: Phenomenology in Science; Psychotherapy in ...

    African Journals Online (AJOL)

    One of the concerns of the existential-phenomenological tradition has been to examine the human implications of living in a world of proliferating technology. The pressure to become more specialised and efficient has become a powerful value and quest. Both contemporary culture and science enables a view of human ...

  6. 'Living' sacrifice and shame: Phenomenological insights into ...

    African Journals Online (AJOL)

    It draws on a broader phenomenological research study into the experiences of students taking a one semester module, Reading and. Writing Academic Texts, specifically designed to promote students' academic literacy development in the Bachelor of Education Honours programme at the University of KwaZulu-Natal.

  7. Phenomenological applications of kT factorization

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 63; Issue 6. Phenomenological applications of T factorization. Yong-Yeon ... Author Affiliations. Yong-Yeon Keum1. Institute of Physics, Academia Sinica, Nankang 128, Taipei 11529, Taiwan Deutsches Elektronen-Synchrotron DESY, 22607 Hamburg, Germany ...

  8. Phenomenological approach to describe logistic growth and ...

    Indian Academy of Sciences (India)

    In this communication, different classes of phenomenological universalities of carrying capacity dependent growth processes have been proposed. The logistic as well as carrying capacity-dependent West-type allometry-based biological growths can be explained in this proposed framework. It is shown that logistic and ...

  9. Aspects of M theory and phenomenology

    CERN Document Server

    Ellis, John R.


    A brief review is presented of selected topics, including a world- sheet formulation of M theory, couplings and scales in M phenomenology, the perils of baryon decay and the possible elevation of free-fermion models to true M- or F-theory compactifications. (35 refs).

  10. A Phenomenology of Outdoor Education Leader Experiences (United States)

    Field, Stephanie C.; Lauzon, Lara L.; Meldrum, John T.


    Limited qualitative research exists on the experiences of outdoor education leaders. The purpose of this phenomenological study was to explore the job-related experiences of outdoor education leaders within and outside the workplace. Five participants who had experience as outdoor education leaders completed in-depth, one-on-one interviews about…

  11. Getting creative with hermeneutic phenomenology in engineering

    DEFF Research Database (Denmark)

    Coxon, Ian Robert


    (Abstract publication only) Getting creative with hermeneutic phenomenology in engineering: New ideas, timely lessons and useful learning from diverse Danish projects,The 32nd International Human Science Research Conference, August 13-16, Aalborg University, Denmark. Available

  12. Light front quantum chromodynamics: Towards phenomenology

    Indian Academy of Sciences (India)

    What makes light front dynamics appealing from high energy phenomenology point of view? ¯ Boost are kinematical: Longitudinal boost becomes a scale transformation and trans- verse boosts are Galilean boosts. ¯ With a cutoff &· > 0 on constituent momentum, vacuum is trivial and hence parton picture makes sense. 241 ...

  13. The Phenomenology of Action: A Conceptual Framework (United States)

    Pacherie, Elisabeth


    After a long period of neglect, the phenomenology of action has recently regained its place in the agenda of philosophers and scientists alike. The recent explosion of interest in the topic highlights its complexity. The purpose of this paper is to propose a conceptual framework allowing for a more precise characterization of the many facets of…

  14. Phenomenology as Embodied Knowing and Sharing: Kindling ...

    African Journals Online (AJOL)

    We are particularly interested in how poetry and phenomenological research come together to increase understanding of human phenomena. We are further interested in how these more aesthetic possibilities of understanding can occur within a community context, that is the possibility of a process in which understanding ...

  15. Phenomenology: A Review of the Literature (United States)

    Randles, Clint


    This article is a review of relevant literature on the use of phenomenology as a research methodology in education research, with a focus on music education research. The review is organized as follows: (a) general education, (b) music research, (c) music education research, (d) dissertations, (e) important figures, (f) themes, and (g) the future.…

  16. Phenomenology and the Interpretation of Psychopathological Experience

    DEFF Research Database (Denmark)

    Parnas, Josef; Gallagher, Shaun


    psychiatric object”; Marková & Berrios, 2009; see also Chapter 2, this volume) as readily operationalizable object-like entities, with a nonstandard phenomenological approach that emphasizes the importance of a specific kind of interpretive interview. The descriptive methods of today's psychiatry perpetuate...

  17. A multisensory phenomenology of interrail mobilities

    DEFF Research Database (Denmark)

    Jensen, Martin Trandberg; Scarles, Caroline; Cohen, Scott A.


    This paper suggests that phenomenological studies of tourism mobilities can be informed by non-representational approaches. We extend recent developments in sensory tourism research and non-representational works to argue that methods upon which tourism researchers have long relied require ‘pushing...

  18. Towards a Post-Hermeneutic Phenomenology

    DEFF Research Database (Denmark)

    Katan, Lina Hauge; Baarts, Charlotte

    with the intellect but also with the senses. We propose an approach to both the making and communication of knowledge, which could be called post-hermeneutic –a phenomenology not aiming at fixation of identified significance, but at a knowing that includes and even takes advantage of the fluctuating and manifold...

  19. Folk Phenomenology and the Offering of Teaching (United States)

    Rocha, Samuel D.


    This article will move in five parts. It begins with some priming notes on the relationship between philosophy of education and curriculum theory. Then it rehearses a collage of selected passages from a recent book, "Folk Phenomenology: Education, Study, and the Human Person" (Rocha, 2015a). Then the author works in a more speculative…

  20. Phenomenological Philosophy and Orthodox Christian Scientific ...

    African Journals Online (AJOL)

    In its place, this paper suggests that phenomenological philosophy becomes the unique and transcendent partner, as it were, in the interpretive dialogue. The methodological thinking of Edmund Husserl and Martin Heidegger offers a way of philosophical understanding that is more satisfactory than the traditional scholastic ...

  1. Medical phenomenology and stroke rehabilitation: an introduction. (United States)

    Goldberg, Gary


    This issue of Topics in Stroke Rehabilitation explores the theme of medical phenomenology and stroke rehabilitation through open peer commentary format. The theme is introduced by a brief summary and overview of phenomenology as a branch of philosophy whose focus is the development of methodology for describing and ordering human experience. The application of this philosophical approach to medicine in general and stroke rehabilitation in particular is then considered. An approach to patients informed by both phenomenology and science provides a more complete, holistic, and humanistic framework than science alone. Phenomenology helps the clinician to understand the importance of narrative, the process of adaptation at the level of the integrated whole person, and the important role of context in determining how recovery unfolds. Embodiment is presented as an organizing principle that links the nature of conscious experience in the lived body and the basic transformation in experience and function associated with an acquired pathology such as stroke. Finally, the nature of open peer commentary is considered and introduced in terms of how it has been specifically implemented in this issue of Topics in Stroke Rehabilitation.

  2. A Hermeneutic Phenomenological Approach to understanding ...

    African Journals Online (AJOL)

    A dual philosophical approach is outlined: a phenomenological perspective apprehends stress-coping as an existential phenomenon, while the hermeneutic focus is on interpreting the links between lived experience and meaning. The kind of knowledge generated by means of this approach offers a new way of ...

  3. Towards a Kantian Phenomenology of Hope

    NARCIS (Netherlands)

    Beyleveld, D.; Ziche, Paul


    The aim of this paper is to examine the extent to which Kant’s Critique of the Power of Judgment (CPoJ) can be, or otherwise ought to be, regarded as a transcendental phenomenology of hope. Kant states repeatedly that CPoJ mediates between the first two Critiques, or between the theoretical

  4. Recovery from Psychosis: A Phenomenological Inquiry (United States)

    Nixon, Gary; Hagen, Brad; Peters, Tracey


    While mainstream psychiatry tends to view psychosis as an enduring and chronic condition, there is growing interest in the possibility of recovery from psychosis. A phenomenological research method was utilized in interviewing 17 individuals who all self-identified as being in recovery from psychosis. The research question was, "What was the lived…

  5. Light front quantum chromodynamics: Towards phenomenology

    Indian Academy of Sciences (India)

    Light front quantum chromodynamics: Towards phenomenology. A HARINDRANATH. Saha Institute of Nuclear Physics, 1/AF Bidhan Nagar, Calcutta 700 064, India. Abstract. We briefly review the application of light front QCD to inclusive deep inelastic scattering. Keywords. Light front dynamics; quantum chromodynamics; ...

  6. Phenomenology and qualitative research: combining the transcendetal orientation of phenomenology with the diversities of lived experience

    DEFF Research Database (Denmark)

    Ravn, Susanne

    In different ways philosophers have emphasized that phenomenology aims at accounting for our capacity for being conscious – for example by aiming at describing the structure of subjective experiences. Accordingly, phenomenology involves a transcendental orientation. In the domain of qualitative...... research, researchers involve in describing lived bodies and lived experiences to further explore and understand the diversities of our embodied practices and experiences. The aim of this paper is to present and discus some of the methodological challenges of combining phenomenology and qualitative...... methodologies. I will specifically focus on discussing how the transcendental orientation of phenomenological descriptions has the potential to work through difference by approaching lived bodies according to their lived situation. The discussion will fall in three parts focusing on: a) how the research design...

  7. Our experience with the aetiological diagnosis of global developmental delay and intellectual disability: 2006-2010. (United States)

    López-Pisón, J; García-Jiménez, M C; Monge-Galindo, L; Lafuente-Hidalgo, M; Pérez-Delgado, R; García-Oguiza, A; Peña-Segura, J L


    Global developmental delay (GDD) and intellectual disability (ID) are common reasons for consultation in paediatric neurology. Results from aetiological evaluations of children with GDD/ID vary greatly, and consequently, there is no universal consensus regarding which studies should be performed. We review our experience with determining aetiological diagnoses for children with GDD/ID who were monitored by the paediatric neurology unit over the 5-year period between 2006 and 2010. During the study period, 995 children with GDD/ID were monitored. An aetiological diagnosis was established for 309 patients (31%), but not in 686 (69%), despite completing numerous tests. A genetic cause was identified in 142 cases (46% of the total aetiologies established), broken down as 118 cases of genetic encephalopathy and 24 of metabolic hereditary diseases. Our data seem to indicate that diagnosis is easier when GDD/ID is associated with cerebral palsy, epilepsy, infantile spasms/West syndrome, or visual deficit, but more difficult in cases of autism spectrum disorders. Genetic studies provide an increasing number of aetiological diagnoses, and they are also becoming the first step in diagnostic studies. Array CGH (microarray-based comparative genomic hybridisation) is the genetic test with the highest diagnostic yield in children with unexplained GDD/ID. The cost-effectiveness of complementary studies seems to be low if there are no clinically suspected entities. However, even in the absence of treatment, aetiological diagnosis is always important in order to provide genetic counselling and possible prenatal diagnosis, resolve family (and doctors') queries, and halt further diagnostic studies. Copyright © 2013 Sociedad Española de Neurología. Published by Elsevier Espana. All rights reserved.

  8. Using Phenomenology to Conduct Environmental Education Research: Experience and Issues (United States)

    Nazir, Joanne


    Recently, I applied a phenomenological methodology to study environmental education at an outdoor education center. In this article, I reflect on my experience of doing phenomenological research to highlight issues researchers may want to consider in using this type of methodology. The main premise of the article is that phenomenology, with its…

  9. The Domain-Specificity of Creativity: Insights from New Phenomenology (United States)

    Julmi, Christian; Scherm, Ewald


    The question of the domain-specificity of creativity represents one of the key questions in creativity research. This article contributes to the discussion by applying insights from "new phenomenology," which is a phenomenological movement from Germany initiated by philosopher Hermann Schmitz. The findings of new phenomenology suggest…

  10. A Short History of Phenomenological Psychology in South Africa

    African Journals Online (AJOL)


    The Indo-Pacific Journal of Phenomenology (IPJP) can be found at The IPJP is a joint ... Phenomenological. Psychology. (As an interesting sidelight; at the end of this block, Peter Parker, now Dr Parker, living in Australia, came to me to say that the ... In 1979 I published An Introduction to Phenomenological.

  11. Putting phenomenology in its place: some limits of a phenomenology of medicine. (United States)

    Sholl, Jonathan


    Several philosophers have recently argued that phenomenology is well-suited to help understand the concepts of health, disease, and illness. The general claim is that by better analysing how illness appears to or is experienced by ill individuals--incorporating the first-person perspective--some limitations of what is seen as the currently dominant third-person or 'naturalistic' approaches to understand health and disease can be overcome. In this article, after discussing some of the main insights and benefits of the phenomenological approach, I develop three general critiques of it. First, I show that what is often referred to as naturalism tends to be misunderstood and/or misrepresented, resulting in straw-man arguments. Second, the concept of normality is often problematically employed such that some aspects of naturalism are actually presupposed by many phenomenologists of medicine. Third, several of the key phenomenological insights and concepts, e.g. having vs. being a body, the alienation of illness, the epistemic role of the first-person perspective, and the idea of health within illness, each bring with them new problems that limit their utility. While acknowledging the possible contributions of phenomenology, these criticisms point to some severe limitations of bringing phenomenological insights to bear on the problems facing philosophy of medicine that should be addressed if phenomenology is to add anything substantially new to its debates.

  12. Phenomenology of depression in older compared with younger adults: meta-analysis. (United States)

    Hegeman, J M; Kok, R M; van der Mast, R C; Giltay, E J


    Late-life depression may differ from early-life depression in its phenomenology. To investigate the effect of age on the phenomenology of major depression. A systematic search was conducted in PubMed, Embase and PsycINFO for all studies examining the relation between age and phenomenology of major depression according to RDC, DSM and ICD criteria. Studies were included only if the age groups were compared at the single-item level using the 17-, 21- or 24-item versions of the Hamilton Rating Scale for Depression; a meta-analysis was done for each item of the 17-item scale. Eleven papers met the inclusion criteria. Older depressed adults, compared with younger depressed adults, demonstrated more agitation, hypochondriasis and general as well as gastrointestinal somatic symptoms, but less guilt and loss of sexual interest. The phenomenology of late-life depression differs only in part from that of early-life depression. Major depression in older people may have a more somatic presentation, whereas feelings of guilt and loss of sexual function may be more prevalent in younger people.

  13. Studies on simple goitre epidemiology and aetiology in Sudan

    International Nuclear Information System (INIS)

    Medani, A. M. H.


    The objectives of this study were to map the prevalence of goiter in Sudan and to study the etiological factors involved. A further objective was to explore the use of serum thyroglobulin (Tg) level in the assessment of endemic goiter. The survey took place in the period from June to November 2006. The survey covered nine cities including Nyala and Elfasher (Western part), Wau (in the South), Atbara and Dongula (in the north), Dmazine (South East), Port Sudan (Eastern part), Kosti and Khartoum (in the Centre ). Khartoum was divided into three different cities Khartoum, Khartoum North and Omdurman. The study included 6181 male and female schoolchildren at the age 6-12 years old. All the children were clinically examined for the presence of goiter using WHO palpation method. Blood samples were randomly collected from 360 children (30-37) from each selected city irrespective of their thyroid status or gender. Serum samples were analyzed for the concentration of T 4 , T 3 , TSH, and Tg. Casual urine samples were also collected from the same selected subjects. Urine samples were analyzed for iodine and thiocyanate concentrations. Water samples were collected from each school and analyzed for the concentration of Ca, Mg, Cl, F and total Hardness. The results indicated that the overall total goiter rate was 40.62%. The highest goiter rate was found in Kosti town (77.67%) and the lowest in Omdurman Khartoum state (12.22%). The overall median urinary iodine excretion (UIE) was 6.55 μg/dl. Iodine deficiency was detected in 70.28% of the children and there were great variations in the median UIE from region to anther started from as low as 2.70μg/d1 in Kosti town 46.40 μg/d1 in Port Sudan city (at the cost of the Red Sed). The overall median concentration of urinary thiocyanate was 0.37 mg/d1. There were also variations in the median levels of urinary thiocyanate from city to another and slightly exceeded the cut off point (0.0.46 mg/d1) in pupils from Wau and Nyala cities

  14. To be objective in Experimental Phenomenology: a Psychophysics application. (United States)

    Burro, Roberto


    Several scientific psychologists consider the approach for the study of perceptive problems of the Experimental Phenomenology is problematic, namely that the phenomenological demonstrations are subjectively based and they do not produce quantifiable results. The aim of this study is to show that Experimental Phenomenology can lead to conclusions objective and quantifiable and propose a procedure allowing to obtain objective measuring using the Rasch mathematical model able to describe the experimental data gathered in Experimental Phenomenology procedures. In order to demonstrate this, a Psychophysics simulated study is proposed. It is possible to carry out a fundamental measurement starting from Experimental Phenomenology by way of the Theory of Conjoint Measurement.

  15. The aetiology of vaginal symptoms in rural Haiti. (United States)

    Bristow, Claire C; Desgrottes, Tania; Cutler, Lauren; Cutler, David; Devarajan, Karthika; Ocheretina, Oksana; Pape, Jean William; Klausner, Jeffrey D


    Vaginal symptoms are a common chief complaint amongst women visiting outpatient clinics in rural Haiti. A systematic sample of 206 consecutive women over age 18 with gynaecological symptoms underwent gynaecologic examination and laboratory testing for chlamydia, gonorrhoea, syphilis, HIV infection, trichomoniasis, candidiasis, and bacterial vaginosis. Among 206 women, 174 (84%) presented with vaginal discharge, 165 (80%) with vaginal itching, 123 (60%) with vaginal pain or dysuria, and 18 (9%) with non-traumatic vaginal sores or boils. Laboratory results were positive forChlamydia trachomatisin 5.4% (11/203), syphilis in 3.5% (7/202), HIV in 1.0% (2/200), andNeisseria gonorrhoeaein 1.0% (2/203). Among those that had microscopy, hyphae suggestive of candidiasis were visualized in 2.2% (1/45) and no cases of trichomoniasis were diagnosed 0% (0/45). Bacterial vaginosis was diagnosed in 28.3% (13/46). The prevalence of chlamydia was 4.9 (95% CI: 1.3-17.7) times greater among those 25 years of age and under (10.8%) than those older (2.3%). Chlamydia and bacterial vaginosis were the most common sexually transmitted infection and vaginal condition, respectively, in this study of rural Haitian adult women. The higher risk of chlamydia in younger women suggests education and screening programmes in young women should be considered. © The Author(s) 2013 Reprints and permissions:

  16. Ruminal Acidosis in Feedlot: From Aetiology to Prevention

    Directory of Open Access Journals (Sweden)

    Joaquín Hernández


    Full Text Available Acute ruminal acidosis is a metabolic status defined by decreased blood pH and bicarbonate, caused by overproduction of ruminal D-lactate. It will appear when animals ingest excessive amount of nonstructural carbohydrates with low neutral detergent fiber. Animals will show ruminal hypotony/atony with hydrorumen and a typical parakeratosis-rumenitis liver abscess complex, associated with a plethora of systemic manifestations such as diarrhea and dehydration, liver abscesses, infections of the lung, the heart, and/or the kidney, and laminitis, as well as neurologic symptoms due to both cerebrocortical necrosis and the direct effect of D-lactate on neurons. In feedlots, warning signs include decrease in chewing activity, weight, and dry matter intake and increase in laminitis and diarrhea prevalence. The prognosis is quite variable. Treatment will be based on the control of systemic acidosis and dehydration. Prevention is the most important tool and will require normalization of ruminal pH and microbiota. Appropriate feeding strategies are essential and involve changing the dietary composition to increase neutral detergent fiber content and greater particle size and length. Appropriate grain processing can control the fermentation rate while additives such as prebiotics or probiotics can help to stabilize the ruminal environment. Immunization against producers of D-lactate is being explored.

  17. Phenomenology and adapted physical activity: philosophy and professional practice. (United States)

    Standal, Øyvind F


    Through the increased use of qualitative research methods, the term phenomenology has become a quite familiar notion for researchers in adapted physical activity (APA). In contrast to this increasing interest in phenomenology as methodology, relatively little work has focused on phenomenology as philosophy or as an approach to professional practice. Therefore, the purpose of this article is to examine the relevance of phenomenology as philosophy and as pedagogy to the field of APA. First, phenomenology as philosophy is introduced through three key notions, namely the first-person perspective, embodiment, and life-world. The relevance of these terms to APA is then outlined. Second, the concept of phenomenological pedagogy is introduced, and its application and potential for APA are discussed. In conclusion, it is argued that phenomenology can help theorize ways of understanding human difference in movement contexts and form a basis of action-oriented research aiming at developing professional practice.

  18. The aetiology of community-acquired pneumonia and implications for patient management.

    NARCIS (Netherlands)

    Gageldonk-Lafeber, A.B. van; Wever, P.C.; Lubben, I.M. van der; Jager, C.P. de; Meijer, A.; Vries, M.C. de; Elberse, K.; Sande, M.A.B. van der; Hoek, W. van der


    PURPOSE: Understanding which pathogens are associated with clinical manifestation of community-acquired pneumonia (CAP) is important to optimise treatment. We performed a study on the aetiology of CAP and assessed possible implications for patient management in the Netherlands. METHODS: Patients

  19. Domestic donkey (Equus africanus asinus bites: An unusual aetiology of severe scalp injuries in Morocco

    Directory of Open Access Journals (Sweden)

    Hatim Droussi


    Discussion: The bite of a donkey is rare aetiology of scalp injuries. Special features of these injuries, including a literature review, are discussed focusing on the care of these patients in the emergency centre, describing the surgical procedures required and antibiotic choice. Recommendations for the management of donkey bite scalp injuries are provided.

  20. Modern views on aetiology and pathogenesis of tumor growths and benign ovarian tumors

    Directory of Open Access Journals (Sweden)

    Serebrennikova K.G.


    Full Text Available The article represents modern data of aetiology and pathogenesis of tumor growths and benign ovarian tumors as systemic diseases of organism. These diseases appear on the cellular level and involve the presence of polymorphous metabolic, endocrine and immune disorders. Exogenous and endogenous risk factors of ovarian carcinomas are considered

  1. Cytoarchitecture of epithelial inflammatory infiltration indicates the aetiology of infectious keratitis. (United States)

    Smedowski, Adrian; Tarnawska, Dorota; Orski, Michal; Wroblewska-Czajka, Ewa; Kaarniranta, Kai; Aragona, Pasquale; Wylegala, Edward


    To analyse cytological features of corneal epithelium in infectious keratitis. One hundred and eighteen patients (53 males and 65 females) diagnosed with acute stage of infectious keratitis (45 viral, 40 bacterial, 23 fungal, 10 Acanthamoeba keratitis) were included in study. We performed retrospective analysis of bright and blue-light slit-lamp photographs and in vivo corneal confocal microscopy scans of the corneal epithelium from five corneal regions (superior, inferior, temporal, nasal and central). Density, morphology of inflammatory cells and their relation to epithelial structures, as well as density of nerve fibres, were evaluated in relation to the keratitis aetiology. We characterized five morphological types of inflammatory cells forming infiltration. Cell and nerve fibre densities showed significant differences between groups, and the most intense inflammatory infiltration was associated with fungal then bacterial, viral and Acanthamoeba keratitis. Additionally, differences in aetiology-specific ratio of round/non-round inflammatory cells were observed. Confocal microscopy analysis in infectious keratitis of various aetiologies revealed quantitative and qualitative differences in inflammatory cell infiltration expressed in different ratio of round/non-round inflammatory cells. In vivo microscopic analysis of both the corneal epithelial layer cytopathology and the cytology of inflammatory infiltration provides a fast and specific differentiation of keratitis aetiology that may increase the accuracy in the selection of the initial treatment. © 2017 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  2. The role of personality pathology in the aetiology and treatment of substance use disorders

    NARCIS (Netherlands)

    Verheul, R; van den Brink, W


    The concept of personality in addiction research has traditionally been subject to controversies about its measurement and role in aetiology and treatment. Early studies (1950-1980) typically sought but failed to identify a single pre-addictive personality, suggesting either clinical heterogeneity

  3. The incidence and aetiology of acute kidney injury in children in Norway between 1999 and 2008 (United States)

    Jenssen, Gaute Reier; Hovland, Eirik; Bangstad, Hans-Jacob; Nygård, Karin; Vold, Line; Bjerre, Anna


    Aim Primary acute kidney injury (AKI) is a direct cause of hospitalisation in children, but can also result from other conditions. There is limited information on the epidemiology of this condition. Our aim was to describe the national incidence rate and aetiology of acute kidney injury in children under the age of 16 in Norway from 1999 to 2008. Methods We carried out a retrospective study of medical records provided by all 18 of the paediatric hospital departments that specialise in treating paediatric patients with AKI. Results We identified 315 cases of AKI (53% male), with an estimated average annual incidence rate of 3.3 cases per 100 000 children and a median annual occurrence of 33 cases. Most cases (43%) were in children under five. We identified 53 aetiologies and classified these into 30 aetiological groups: 24% of the cases were prerenal (n = 75), 74% were intrinsic/renal (n = 234) and 2% were postrenal (n = 5). Nephritic syndromes was the major cause (44%) of AKI, followed by haemolytic-uraemic syndrome (HUS) (15%). Conclusion Nephritic syndromes and HUS are the most common aetiologies of AKI in Norway. Although our results could indicate a low incidence of paediatric AKI in Norway, the lack of other national studies makes comparisons difficult. PMID:25039408

  4. Aetiological profile of nasal trauma in Ilorin North-Central Nigeria ...

    African Journals Online (AJOL)

    Background: The nose being the most prominent part of the face is easily traumatized in facial injuries and these has been found to be common among the Caucasians compared to the Africans and Asians. The aim is to ighlight the Aetiological profile of nasal trauma in Ilorin orth-central Nigeria. Method: A prospective study ...

  5. Perspectives on the Aetiology of ODD and CD: A Grounded Theory Approach (United States)

    McFarland, Patrick; Sanders, James; Hagen, Bradley


    Antisocial disorders, such as oppositional defiant disorder (ODD) and conduct disorder (CD), are common reasons for youth to be seen for clinical intervention. The intent of this constructivist grounded theory study was to evaluate clinicians' perspectives on the aetiology of antisocial disorders. Six professionals from various professional…

  6. Neonatal seizures : Aetiology by means of a standardized work-up

    NARCIS (Netherlands)

    Loman, Annemiek M. W.; ter Horst, Henk J.; Lambrechtsen, Florise A. C. P.; Lunsing, Roelineke J.

    Neonatal seizures are an alarming symptom and are frequent in neonates. It is important to find the cause of neonatal seizures to start a specific treatment and to give a meaningful prognosis. The aim of this study is to investigate the incidence of different aetiologies of neonatal seizures in our

  7. Systematic review of survival after acute mesenteric ischaemia according to disease aetiology

    NARCIS (Netherlands)

    Schoots, I. G.; Koffeman, G. I.; Legemate, D. A.; Levi, M. [=Marcel M.; van Gulik, T. M.


    BACKGROUND: Differentiation of acute mesenteric ischaemia on the basis of aetiology is of great importance because of variation in disease progression, response to treatment and outcome. The aim of this study was to analyse the published data on survival following acute mesenteric ischaemia over the

  8. Age-related risk factors for bacterial aetiology in community-acquired pneumonia. (United States)

    Sahuquillo-Arce, José M; Menéndez, Rosario; Méndez, Raúl; Amara-Elori, Isabel; Zalacain, Rafael; Capelastegui, Alberto; Aspa, Javier; Borderías, Luis; Martín-Villasclaras, Juan J; Bello, Salvador; Alfageme, Inmaculada; de Castro, Felipe Rodriguez; Rello, Jordi; Molinos, Luis; Ruiz-Manzano, Juan; Torres, Antoni


    The objective of this study was to evaluate the effect of age and comorbidities, smoking and alcohol use on microorganisms in patients with community-acquired pneumonia (CAP). A prospective multicentre study was performed with 4304 patients. We compared microbiological results, bacterial aetiology, smoking, alcohol abuse and comorbidities in three age groups: young adults (65 years). Bacterial aetiology was identified in 1522 (35.4%) patients. In seniors, liver disease was independently associated with Gram-negative bacteria (Haemophilus influenzae and Enterobacteriaceae), COPD with Pseudomonas aeruginosa (OR = 2.69 (1.46-4.97)) and Staphylococcus aureus (OR = 2.8 (1.24-6.3)) and neurological diseases with S. aureus. In adults, diabetes mellitus (DM) was a risk factor for Streptococcus pneumoniae and S. aureus, and COPD for H. influenzae (OR = 3.39 (1.06-10.83)). In young adults, DM was associated with S. aureus. Smoking was a risk factor for Legionella pneumophila regardless of age. Alcohol intake was associated with mixed aetiology and Coxiella burnetii in seniors, and with S. pneumoniae in young adults. It should be considered that the bacterial aetiology may differ according to the patient's age, comorbidities, smoking and alcohol abuse. More extensive microbiological testing is warranted in those with risk factors for infrequent microorganisms. © 2016 Asian Pacific Society of Respirology.

  9. Prospective evaluation of the aetiological profile of acute pancreatitis in young adult patients. (United States)

    Culetto, Adrian; Bournet, Barbara; Haennig, Audrey; Alric, Laurent; Peron, Jean-Marie; Buscail, Louis


    The aetiologies of acute pancreatitis in young adult patients are poorly known. To prospectively evaluate the causes of acute pancreatitis in patients aged less than 35 years. Overall, 309 consecutive patients admitted to our centre for acute pancreatitis received first-line investigations, including medical history, standard laboratory tests, abdominal ultrasound and computed tomography. If no aetiology was found, second-line investigations were performed, including endoscopic ultrasound, magnetic-resonance cholangiopancreatography and genetic testing in cases of idiopathic pancreatitis. Overall, 66 patients aged between 16 and 35 years were included. After first-line investigations, 49% of cases of acute pancreatitis remained idiopathic. Second-line investigations reduced this rate to 21%. The frequency of aetiologies for acute pancreatitis significantly differed in adults aged ≤ 35 compared to those aged >35 years: biliary aetiology was less frequent (23% versus 43%, p=0.003) as well as alcohol-related (8% versus 24%, p=0.01); drug-induced was more common (16% versus 4%, p=0.0007), as well as cannabis-related (13% versus 1%, pacute pancreatitis significantly differed in adults aged less than 35 years when compared to older patients. Thus, use of medications, exposure to cannabis, and genetic mutations should be actively sought in these patients. Copyright © 2015 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

  10. Epilepsy in sub-Saharan Africa: its socio-demography, aetiology ...

    African Journals Online (AJOL)

    Objective: To assess epileptics with regard to socio-demographic characteristics, aetiology, EEG results and classification. Design: A descriptive cohort study from 1997 to 2001. Setting: Parirenyatwa Group of Hospitals in Harare, Zimbabwe. Subjects: A total of 229 consecutive epileptic subjects. Results: The mean (s.d.) ...

  11. A review of the current literature on aetiology and measurement methods of halitosis.

    NARCIS (Netherlands)

    Broek, A.M. van den; Feenstra, L.; Baat, C. de


    OBJECTIVES: This work reviews the current knowledge of aetiology and measurement methods of halitosis. DATA: Halitosis is an unpleasant or offensive odour emanating from the breath. The condition is multifactorial and may involve both oral and non-oral conditions. SOURCES: A private, monthly with

  12. Does the sun play a role in the aetiology of malignant melanoma ...

    African Journals Online (AJOL)

    The role of the sun in the aetiology of malignant melanoma is controversial. In 1992 Schuster1 wrote provocatively, 'Despite the lack of evidence of a causal link between sun exposure and melanoma, fear has been used shamelessly to frighten people out of the sun and into pigmented lesion clinics.' He claimed that the ...

  13. Phenomenology of quark-lepton symmetric models

    International Nuclear Information System (INIS)

    Foot, R.; Lew, H.; Volkas


    Quark-lepton symmetric models are a new class of gauge theories which unify the quarks and leptons. In these models the gauge group of the standard model is extended to include a color group for the leptons, and consequently the quarks and leptons can then be related by a Z 2 discrete quark-lepton symmetry. Phenomenological implications of these theories are explored. Two varieties are analysed: one being the simplest quark-lepton symmetric model, and the other containing conventional left-right symmetry. Each theory has a Z' boson, whose masses are constrained at 90% C.L. to be greater than 700 GeV and 650 GeV respectively. Phenomenological constraints from rare decays and the implications of the extended fermion spectrum are also examined. 37 refs., 2 tabs

  14. The Role of Aesthetics for Design Phenomenology

    DEFF Research Database (Denmark)

    Folkmann, Mads Nygaard

    The aim of the paper is to conceptualize the means and effects of different dimensions of aesthetic meaning in relation to the experience of design. In doing so, the paper combines two philosophical interests in design, design phenomenology and design aesthetics, in order to promote a framework...... for discussing the impact of aesthetic meaning construction on experience. First, the paper raises the phenomenological question of the relationship between design and experience, specifically, how design conditions experience. Second, in looking at aesthetics in terms of a) the sensual appeal of design, b...... our experience: We can look at sensual, conceptual, and contextual aesthetic dimensions of design and examine their contribution to the framing of experience, that is, how different dimensions of meaning articulation in design offer different framings of the experiences promoted by design objects...

  15. Conceptualizing Aesthetics in Design: A Phenomenological Framework

    DEFF Research Database (Denmark)

    Folkmann, Mads Nygaard


    of aesthetic meaning construction on experience. First, the chapter raises the phenomenological question of the relationship between design and experience, specifically, how design conditions experience. Second, in looking at aesthetics in terms of a) the sensual appeal of design, b) design objects......The aim of this chapter is to introduce and discuss aesthetics as an approach to understand how design frames experience. In doing so, the chapter combines two philosophical interests in design, design phenomenology and design aesthetics, in order to promote a framework for discussing the impact...... experience: We can look at sensual, conceptual, and contextual aesthetic dimensions of design and examine their contribution to the framing of experience, that is, how different dimensions of meaning articulation in design offer different framings of the experiences promoted by design objects and solutions...

  16. [How to think a phenomenological clinic]. (United States)

    Rovaletti, María L


    The emergence of Phenomenology cannot to be understood outside the context of naturalism, the crisis affecting the philosophy and the scientific foundation of psychology toward the end of the 19th century. Binswanger thinks Husserl's attempt to found the experience of the things themselves in intentional living structures can to be useful to guide the psychiatric examination. For that, he seeks in the fundamental dimensions of existence, the conditions of possibility of being sick, which are also those of the same psychiatry. While the phenomenological psycho(patho)logy has not born of direct confrontation with patients, it doesn't mean that it doesn't have internal references with practice. It's proposed then a semiological Eidetic founded in multiple modes of intentionality, or "basic categories", opposite of semiology supported on psychic functions. From etiology to the anthropological a priori of mental illnesses, from the symptom to the phenomenon, here are two possible readings in the field of the clinic.

  17. Phenomenological Mechanochemistry of Damage in Electromagnetic Fields (United States)

    Grinfeld, Michael; Grinfeld, Pavel


    Basic principles of Phenomenological Mechanochemistry of Damage (PMD) have been formulated in Grinfeld and Wright. To some extent, it is a natural extension of the traditional damage theory, presented by Kachanov. Contrary to Kachanov's approach, the PMD theory includes, in addition to the bulk elastic energy, the energy associated with braking/recovery of chemical bonds. Therefore, in addition to the elasticity equations it includes the equation, describing evolution/dynamics of chemical bonds. Although ``chemical bonds'' is a nano-scale concept, we treat the bonds using phenomenological approach. The additional equation of damage evolution is of the rate type, thus, making the whole model rate-dependent (even in quasi-static approach.) In the paper, we review some earlier results and generalized them by taking into account electromagnetic effects.

  18. Electroweak and Strong Interactions Phenomenology, Concepts, Models

    CERN Document Server

    Scheck, Florian


    Electroweak and Strong Interaction: Phenomenology, Concepts, Models, begins with relativistic quantum mechanics and some quantum field theory which lay the foundation for the rest of the text. The phenomenology and the physics of the fundamental interactions are emphasized through a detailed discussion of the empirical fundamentals of unified theories of strong, electromagnetic, and weak interactions. The principles of local gauge theories are described both in a heuristic and a geometric framework. The minimal standard model of the fundamental interactions is developed in detail and characteristic applications are worked out. Possible signals of physics beyond that model, notably in the physics of neutrinos are also discussed. Among the applications scattering on nucleons and on nuclei provide salient examples. Numerous exercises with solutions make the text suitable for advanced courses or individual study. This completely updated revised new edition contains an enlarged chapter on quantum chromodynamics an...

  19. Phenomenology of microwave coupling, part 1 (United States)

    King, R. J.; Breakall, J. K.; Hudson, H. G.; Morrison, J. J.; McGevna, V. G.; Kunz, K. S.; Ludwigsen, A. P.; Gnade, D. K.


    Advances in the development of high power microwave sources have increased the potential for future deployment of microwave weapons. A key ingredient in being able to predict the vulnerability of military systems to such threats involves understanding the phenomenology of how electromagnetic energy couples into cavity like objects, or the so called back door coupling. A similar but much longer standing problem is that of nuclear electromagnetic pulses (EMP) in which the frequencies extend up to several hundreds of MHz. However, compared to EMP coupling, microwave coupling is distinctively different because the wavelength is comparable to the size of the ports of entry. Coupling paths can be highly resonant at certain microwave frequencies, making the shielding against microwave threats difficult. The initial efforts at Lawrence Livermore National Laboratory to study the phenomenology of back door coupling at the low microwave frequencies (up to 2.5 GHz) are summarized.

  20. Phenomenological Study of Youth Lifestyles in Tehran

    Directory of Open Access Journals (Sweden)

    Mehdi Fallah


    Full Text Available This study has tried to investigate and reconstruct the meaning of life style in a phenomenological approach among young people in Tehran city. Most research done on this issue has been described by adopting deductive strategy and underlying prefabricated theories.While the phenomenological method focuses on how humans meant their experiences and transform them to collective and personal form of their consciousness. It also requires a methodologicalunderstandingthat how humans experience these phenomena. Researcher to collect such data is necessary to engage in-depth interviews with people who have directly experienced the phenomenon of interest that means they have Lived experience that is in contrast with second order experience and the operating variables that derived from metanarratives. Thus, we have distinguished four major lifestyles of young people’s lives in Tehran according to Husserl’s epoche manner and meet schutz’s typification criteria that contain; pleasure seeking - aesthetic lifestyle, functionalistic, subcultural and passive.

  1. Towards a Relational Phenomenology of Violence


    Staudigl, Michael


    This article elaborates a relational phenomenology of violence. Firstly, it explores the constitution of all sense in its intrinsic relation with our embodiment and intercorporality. Secondly, it shows how this relational conception of sense and constitution paves the path for an integrative understanding of the bodily and symbolic constituents of violence. Thirdly, the author addresses the overall consequences of these reflections, thereby identifying the main characteristics of a relational...

  2. Why natural science needs phenomenological philosophy. (United States)

    Rosen, Steven M


    Through an exploration of theoretical physics, this paper suggests the need for regrounding natural science in phenomenological philosophy. To begin, the philosophical roots of the prevailing scientific paradigm are traced to the thinking of Plato, Descartes, and Newton. The crisis in modern science is then investigated, tracking developments in physics, science's premier discipline. Einsteinian special relativity is interpreted as a response to the threat of discontinuity implied by the Michelson-Morley experiment, a challenge to classical objectivism that Einstein sought to counteract. We see that Einstein's efforts to banish discontinuity ultimately fall into the "black hole" predicted in his general theory of relativity. The unavoidable discontinuity that haunts Einstein's theory is also central to quantum mechanics. Here too the attempt has been made to manage discontinuity, only to have this strategy thwarted in the end by the intractable problem of quantum gravity. The irrepressible discontinuity manifested in the phenomena of modern physics proves to be linked to a merging of subject and object that flies in the face of Cartesian philosophy. To accommodate these radically non-classical phenomena, a new philosophical foundation is called for: phenomenology. Phenomenological philosophy is elaborated through Merleau-Ponty's concept of depth and is then brought into focus for use in theoretical physics via qualitative work with topology and hypercomplex numbers. In the final part of this paper, a detailed summary is offered of the specific application of topological phenomenology to quantum gravity that was systematically articulated in The Self-Evolving Cosmos (Rosen, 2008a). Copyright © 2015. Published by Elsevier Ltd.

  3. Model building and phenomenology in supersymmetry

    International Nuclear Information System (INIS)

    Kim, Jong Soo


    Supersymmetry (SUSY) stabilizes the hierarchy between the electroweak scale and the scale of grand unified theories (GUT) or the Planck scale. The simplest supersymmetric extension of the SM, the minimal supersymmetric SM (MSSM) solves several phenomenological problems, e. g. the gauge couplings unify and the lightest supersymmetric particle (LSP) is a dark matter candidate. In this thesis, Jarlskog invariants, squark pair production at the LHC and massive neutrinos are discussed in the framework of the MSSM and its extensions. (orig.)

  4. Model building and phenomenology in supersymmetry

    Energy Technology Data Exchange (ETDEWEB)

    Kim Jong Soo


    Supersymmetry (SUSY) stabilizes the hierarchy between the electroweak scale and the scale of grand unified theories (GUT) or the Planck scale. The simplest supersymmetric extension of the SM, the minimal supersymmetric SM (MSSM) solves several phenomenological problems, e. g. the gauge couplings unify and the lightest supersymmetric particle (LSP) is a dark matter candidate. In this thesis, Jarlskog invariants, squark pair production at the LHC and massive neutrinos are discussed in the framework of the MSSM and its extensions. (orig.)

  5. Phenomenology in minimal theory of massive gravity (United States)

    De Felice, Antonio; Mukohyama, Shinji


    We investigate the minimal theory of massive gravity (MTMG) recently introduced. After reviewing the original construction based on its Hamiltonian in the vielbein formalism, we reformulate it in terms of its Lagrangian in both the vielbein and the metric formalisms. It then becomes obvious that, unlike previous attempts in the literature of Lorentz-violating massive gravity, not only the potential but also the kinetic structure of the action is modified from the de Rham-Gabadadze-Tolley (dRGT) massive gravity theory. We confirm that the number of physical degrees of freedom in MTMG is two at fully nonlinear level. This proves the absence of various possible pathologies such as superluminality, acausality and strong coupling. Afterwards, we discuss the phenomenology of MTMG in the presence of a dust fluid. We find that on a flat homogeneous and isotropic background we have two branches. One of them (self-accelerating branch) naturally leads to acceleration without the genuine cosmological constant or dark energy. For this branch both the scalar and the vector modes behave exactly as in general relativity (GR). The phenomenology of this branch differs from GR in the tensor modes sector, as the tensor modes acquire a non-zero mass. Hence, MTMG serves as a stable nonlinear completion of the self-accelerating cosmological solution found originally in dRGT theory. The other branch (normal branch) has a dynamics which depends on the time-dependent fiducial metric. For the normal branch, the scalar mode sector, even though as in GR only one scalar mode is present (due to the dust fluid), differs from the one in GR, and, in general, structure formation will follow a different phenomenology. The tensor modes will be massive, whereas the vector modes, for both branches, will have the same phenomenology as in GR.

  6. A hermeneutic phenomenological enquiry into homelessness


    Eustace, Susan


    Research into homelessness has been predominantly quantitative in design, solution-focused and may have effectively concealed the phenomenon itself. This study utilised a hermeneutic phenomenological methodology, based on Martin Heidegger’s philosophy, to reveal some essential, constitutive characteristics of homelessness. In-depth qualitative interviews were conducted with six participants accessed through a service provider for homeless persons. Passing Time and Taking Care emerged as essen...

  7. Death in the Perspective of Existential Phenomenology

    Directory of Open Access Journals (Sweden)

    Tomas Kačerauskas


    Full Text Available The article deals with the interconnection between death and ethics in the perspectives of existential phenomenology and phenomenological historics. The M. Heidegger’s conception of being-towards-death has been contrasted with the Ricœur’s conceptions of birth and forgiveness, as well as with Levinas’ ethical priority regarding ontology. The major thesis of the article is the following: the life as an existential project under implementation is bracketing of the death. The minor theses are the following: 1 “death” is a criterion of demarcation (border stone between existential (ontological and eidetic phenomenology; 2 a certain “death’s” bracketing emerging as an interpretation of technē ton bion being to develope signifies the ethical approach, which opens the contiguity of ontological and ethical regions. According to the author, the ethical and ontological regions have been contiguous in the poetical language as in a form of existential creation by imagining historical co-existence.  

  8. Photochemical Phenomenology Model for the New Millennium (United States)

    Bishop, James; Evans, J. Scott


    The "Photochemical Phenomenology Model for the New Millennium" project tackles the issue of reengineering and extension of validated physics-based modeling capabilities ("legacy" computer codes) to application-oriented software for use in science and science-support activities. While the design and architecture layouts are in terms of general particle distributions involved in scattering, impact, and reactive interactions, initial Photochemical Phenomenology Modeling Tool (PPMT) implementations are aimed at construction and evaluation of photochemical transport models with rapid execution for use in remote sensing data analysis activities in distributed systems. Current focus is on the Composite Infrared Spectrometer (CIRS) data acquired during the CASSINI flyby of Jupiter. Overall, the project has stayed on the development track outlined in the Year 1 annual report and most Year 2 goals have been met. The issues that have required the most attention are: implementation of the core photochemistry algorithms; implementation of a functional Java Graphical User Interface; completion of a functional CORBA Component Model framework; and assessment of performance issues. Specific accomplishments and the difficulties encountered are summarized in this report. Work to be carried out in the next year center on: completion of testing of the initial operational implementation; its application to analysis of the CASSINI/CIRS Jovian flyby data; extension of the PPMT to incorporate additional phenomenology algorithms; and delivery of a mature operational implementation.

  9. Phenomenology of BWR fuel assembly degradation (United States)

    Kurata, Masaki; Barrachin, Marc; Haste, Tim; Steinbrueck, Martin


    Severe accidents occurred at the Fukushima-Daiichi Nuclear Power Station (FDNPS) which required an immediate re-examination of fuel degradation phenomenology. The present paper reviews the updated knowledge on the phenomenology of the fuel degradation, focusing mainly on the BWR fuel assembly degradation at the macroscopic scale and that of the individual interactions at the meso-scale. Oxidation of boron carbide (B4C) control rods potentially generates far larger amounts of heat and hydrogen under BWR accident conditions. All integral tests with B4C control rods or control blades have shown early failure, liquefaction, relocation and oxidation of B4C starting at temperatures around 1250 °C, well below the significant interaction temperatures of UO2-Zry. These interactions or reactions potentially influence the progress of fuel degradation in the early phase. The steam-starved conditions, which are being discussed as a likely scenario at the FDNPS accident, highly influence the individual interactions and potentially lead the fuel degradation in non-prototypical directions. The detailed phenomenology of individual interactions and their influence on the transient and on the late phase of the severe accidents are also discussed.

  10. Recent Research on Aetiology, Development and Phenomenology of Self-Injurious Behaviour in People with Intellectual Disabilities: A Systematic Review and Implications for Treatment (United States)

    Furniss, F.; Biswas, A. B.


    Background: Behavioural interventions conceptualise self-injurious behaviour (SIB) as developing from early repetitive behaviours through acquisition of homeostatic functions in regulating stimulation and subsequent shaping into SIB through socially mediated or automatic operant reinforcement. Despite high success rates, such interventions rarely…

  11. Research approaches related to phenomenology: negotiating a complex landscape. (United States)

    Dowling, Maura; Cooney, Adeline


    To provide a comprehensive overview of the many research approaches related to phenomenology and their philosophical underpinnings. Phenomenological research approaches are varied and often difficult to apply appropriately. Some researchers persist in labelling their studies as examples of Heideggerian or Husserlian phenomenology without fully understanding the implications of the underpinning philosophical assumptions. Methodological sources related to phenomenology as a philosophy and phenomenology as a research approach are used to illustrate the range of phenomenological methods and their philosophical underpinnings. The origins of phenomenology are the writings of Husserl and the advancement of his thoughts by Merleau-Ponty, Heidegger, Gadamer and Ricoeur. The importance of fully understanding a methodology and its philosophical underpinnings before using it, or claiming to use it, is emphasised. In addition, the variety of phenomenological research approaches that have evolved over the past 50 years are explored and placed in the context of their philosophical underpinnings. There is no single way to conduct a phenomenological study. There are many approaches from which researchers can choose. This has resulted in a range of labels and often in different descriptions for the same approach. It is essential that researchers planning to use phenomenology are familiar with the many approaches available. This knowledge will help researchers choose the approaches that best suit the aims of their studies.

  12. Medicine and the individual: is phenomenology the answer? (United States)

    Gergel, Tania L


    The issue of how to incorporate the individual's first-hand experience of illness into broader medical understanding is a major question in medical theory and practice. In a philosophical context, phenomenology, with its emphasis on the subject's perception of phenomena as the basis for knowledge and its questioning of naturalism, seems an obvious candidate for addressing these issues. This is a review of current phenomenological approaches to medicine, looking at what has motivated this philosophical approach, the main problems it faces and suggesting how it might become a useful philosophical tool within medicine, with its own individual, but interrelated, contribution to make to current medical debates. After the general background, there is a brief summary of phenomenological ideas and their current usage in a medical context. Next is a critique of four key claims within current phenomenological medical works, concerning both the role phenomenology plays and the supposedly clear divide between phenomenology and other approaches. There are significant problems within these claims, largely because they overlook the complexity of the questions they consider. Finally, there is some more in-depth examination of phenomenology itself and the true complexity of phenomenological debate concerning subjectivity. The aim is to show that it will be both more productive and truer to phenomenology itself, if we use phenomenology as a philosophical method for explicating and gaining deeper understanding of complex and fundamental problems, which are central to medicine, rather than as providing simple, but flawed solutions. © 2012 Blackwell Publishing Ltd.

  13. Bacterial Aetiology and Antibiotic Resistance Pattern of Community-Acquired Urinary Tract Infections in Children in a Tertiary Care Hospital in Bangladesh

    Directory of Open Access Journals (Sweden)

    Lazina Sharmin


    Full Text Available Background: Urinary tract infections (UTIs in children are among the most common bacterial infections. Community-acquired urinary tract infections (CAUTI are often treated empirically with broad-spectrum antibiotics. Pattern of aetiologic agents and their antibiotic sensitivity may vary according to geographical and regional location. So, knowledge of antibiotic resistance trends is important for improving evidence-based recommendations for empirical treatment of UTIs. Objectives: To determine the common bacterial aetiologies of CAUTIs and their antibiotic resistance patterns in a tertiary care hospital, Savar. Materials and Methods: This cross-sectional descriptive study was conducted at Enam Medical College Hospital, Savar from May 2016 to April 2017. We collected clean-catch mid-stream urine samples from 257 patients having clinical diagnosis of UTI and submitted to the clinical microbiology laboratory for culture and sensitivity. Results: A total of 120 (46.7% samples were positive for bacterial growth. Escherichia coli (79% was the most common pathogen, followed by Klebsiella spp. (14%. Bacterial isolates showed high prevalence of resistance to multiple antibiotics. Resistance against amoxicillin/clavulanic acid, co-trimoxazole and ciprofloxacin was higher compared to newer quinolones and aminoglycosides. Conclusion: Esch. coli and Klebsiella spp. were the predominant bacterial pathogens. The resistance pattern to commonly prescribed antibiotics was quite high and alarming.


    Directory of Open Access Journals (Sweden)



    Full Text Available BACKGROUND Acute pancreatitis is a common condition involving the pancreas. The estimated incidence is about 3% of cases presenting with pain abdomen in the UK. The hospital admission rate for acute pancreatitis is 9.8/100,000 per year in UK and annual incidence may range from 5-50/100,000 worldwide. Gall stone disease and alcohol account for greater than 80% of all patients with acute pancreatitis, with biliary disease accounting for 45% and alcohol found in 35% of patients. Given the wide spectrum of disease seen, the care of patients with pancreatitis must be highly individualised. Patients with mild acute pancreatitis generally can be managed with resuscitation and supportive care. Aetiological factors are sought and treated, if possible, but operative therapy essentially has no role in the care of these patients. Those with severe and necrotising pancreatitis require intensive therapy, which may include wide operative debridement of the infected pancreas or surgical management of local complications of the disease. AIM OF THE STUDY 1. To study the age and sex prevalence of acute pancreatitis. 2. To study the various aetiological factors of acute pancreatitis. 3. To study the clinical presentation and management of acute pancreatitis. MATERIALS AND METHODS Patients admitted to the Department of General Surgery at M.K.C.G Medical College and Hospital, Berhampur were taken up for the study. Totally, 49 patients with 53 episodes of acute pancreatitis were studied from September 2013 to August 2015. RESULTS AND CONCLUSIONS Acute pancreatitis is a common cause of acute abdomen in patients presenting to the surgical emergency department. Alcohol being the most common cause of acute pancreatitis in this part of the country, it has a male preponderance and most commonly presents in the 4th decade of life. It is mainly a clinical diagnosis supplanted with biochemical and radiological findings. The management is mainly conservative, with surgery

  15. Influence of phenomenology and existentialism on Gestalt therapy


    BORIS, Georges Daniel Janja Bloc; MELO, Anna Karynne; MOREIRA, Virginia


    Abstract The literature on the influence of phenomenology and existentialism on Gestalt therapy is controversial because its founders did not clarify its philosophical and epistemological foundations. However, we understand that various influences exerted on Perls and his collaborators during the development of the Gestalt therapy led to a phenomenological-existential approach. The possible influences of phenomenology and existentialism on Gestalt therapy are discussed based on literature rev...

  16. From essence to Lebenswelt as a method in phenomenological psychopathology




    Abstract The use of different phenomenological philosophies as a methodological inspiration in psychopathology certainly leads to methodological implications that must be taken into account. Karl Jaspers, who was inspired by Husserl's transcendental phenomenology, sought the essence so as to reach the generality of the lived psychopathology, thereby giving birth to general psychopathology. This paper advocates for the ambiguous phenomenological method, inspired by Merleau-Ponty's philosophy o...

  17. Incidence and aetiology of talipes equino-varus with recent population changes. (United States)

    Paton, Robin W; Fox, Anna E; Foster, Anne; Fehily, Max


    This study looks at the changing incidence and aetiology of congenital talipes equinovarus due to the recent population changes within the area. Between 1st June 1992 and the 31st May 2006, 83 consecutive children (121 feet) born with fixed talipes equinovarus (TEV) were assessed and treated (an incidence of 1.6 per 1000 live births) in an observational longitudinal cohort study assessing associated factors. There were 17 syndromal cases in the fixed group (20.8%), 6 cases of non-syndromal distal arthrogryposis (7.2%), and a strong family history in 12 cases (14.5%). This study would suggest that genetic and primary causes of fixed TEV are more common than previously considered. Many of the primary aetiologies were diagnosed months or years after birth.

  18. The aetiology of borderline personality disorder (BPD): contemporary theories and putative mechanisms. (United States)

    Winsper, Catherine


    This article presents an overview of current knowledge regarding the aetiology of Borderline Personality Disorder (BPD). It begins with a brief synopsis of early research and theory, and discusses how changing conceptualisations of BPD have impacted on our aetiological knowledge. Contemporary theories are described and presented within a developmental psychopathology framework. Deficient co-regulation and social communication in infancy are purported to underpin emotional dysregulation and social cognition deficits across development. These mechanisms are further potentiated by maladaptive social experiences in a series of positive feedback loops. Prospective research provides preliminary evidence for the reciprocal (or mediating) effects of maladaptive experiences and childhood dysregulation. Moving forward, cohort studies may incorporate neurobiological assessments to examine the biological systems underpinning phenotypic (e.g., impulsivity, disturbed relatedness) covariation. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

  19. Aetiology and pathology of otitis media with effusion in adult life. (United States)

    Mills, R; Hathorn, I


    To gather and analyse information concerning the aetiology and pathology of otitis media with effusion in adults. A review of the English language literature from 1970 to the present was conducted. The available evidence suggests that otitis media with effusion in adult life is best viewed as a syndrome with a number of causes, including: infiltration of the eustachian tube by nasopharyngeal carcinoma and other local malignancies; changes in the middle ear and eustachian tube induced by radiotherapy; and systemic disease. There is now a body of evidence specifically related to the aetiology and pathology of otitis media with effusion in adult life. However, further research is required to fill in the gaps in our knowledge and understanding of this condition.

  20. The aetiology of acute and chronic pancreatitis over time in a hospital in Copenhagen

    DEFF Research Database (Denmark)

    Nøjgaard, Camilla; Bendtsen, Flemming; Matzen, Peter


    INTRODUCTION: The change in aetiology over time of acute and chronic pancreatitis has been sparsely described, as has also the validity of the diagnostic codes. The aim of the study was 1) to clarify whether the aetiology of acute and chronic pancreatitis changed during the period 1983-2005, and 2......) to validate the diagnostic codes over time for acute and chronic pancreatitis registered in the Danish National Patient Registry (NPR) in the same period. MATERIAL AND METHODS: All admissions at Hvidovre Hospital coded in the NPR in 1983, 1994 and 2005 with a diagnosis of either acute or chronic pancreatitis......: Gallstone disease significantly (p = 0.04) increased as the cause of acute pancreatitis over the 22-year period, while alcohol remained the major cause of chronic pancreatitis. The validity of the diagnoses for patients with acute pancreatitis varied between 51% and 73%, and for chronic pancreatitis between...

  1. Chronic kidney disease of unknown aetiology and ground-water ionicity: study based on Sri Lanka. (United States)

    Dharma-Wardana, M W C; Amarasiri, Sarath L; Dharmawardene, Nande; Panabokke, C R


    High incidence of chronic kidney disease of unknown aetiology (CKDU) in Sri Lanka is shown to correlate with the presence of irrigation works and rivers that bring-in 'nonpoint source' fertilizer runoff from intensely agricultural regions. We review previous attempts to link CKDU with As, Cd and other standard toxins. Those studies (e.g. the WHO-sponsored study), while providing a wealth of data, are inconclusive in regard to aetiology. Here, we present new proposals based on increased ionicity of drinking water due to fertilizer runoff into the river system, redox processes in the soil and features of 'tank'-cascades and aquifers. The consequent chronic exposure to high ionicity in drinking water is proposed to debilitate the kidney via a Hofmeister-type (i.e. protein-denaturing) mechanism.

  2. Subjectivity and intersubjectivity between semiotics and phenomenology

    Directory of Open Access Journals (Sweden)

    Francesco Marsciani


    Full Text Available A semiotic theory of subjectivity cannot prescind from a radical consideration of the intersubjective dimension, which, from the phenomenological perspective, represents the constitutive instance of the meaning of the world. The theory of signification has yet to come to terms with this fundamental option: the theory of enunciation, for example, is still tied to the alternative between an egological perception of the production of meaning and a truly intersubjective conception. A radically intersubjective understanding of the constitution of meaning must, in the theory of enunciation, include an authentic theory of alterity in which the production of communicative intentions can be described based on a more fundamental transcendental intentionality.

  3. A phenomenological model for nuclear multifragmentation

    International Nuclear Information System (INIS)

    Souza, S.R.; Leray, S.; Paula, L. de; Nemeth, J.; Ngo, C.; CEA Centre d'Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette; Ngo, H.


    A phenomenological model for nuclear multifragmentation is presented. It is made up of two complementary parts: molecular dynamics and restructured aggregation. It is applied to study the multifragmentation of 16 O+ 80 Br system at several bombarding energies. The results turn out to be in good agreement with available emulsion data. The production of charged particles and IMF as a function of the bombarding energy is also studied. The results seem to agree quite well with experimental observations and with previous results of other model calculations. (author) 19 refs.; 5 figs.; 1 tab

  4. Phenomenology of the deuteron electromagnetic form factors

    International Nuclear Information System (INIS)

    David Abbott; Abdellah Ahmidouch; H. Anklin; J. Arvieux; James P. Ball; Shelton Beedoe; Elizabeth Beise; Louis Bimbot; Werner Boeglin; Herbert Breuer; Roger Carlini; Nicholas Chant; Samuel Danagoulian; K. Dow; Jean-Eric Ducret; Jim Dunne; Lars Ewell; L. Eyraud; C. Furget; Michel Garcon; Ron Gilman; Charles Glashausser; Paul Gueye; Kenneth Gustafsson; Kawtar Hafidi; A. Honegger; J. Jourdan; Serge Kox; Gerfried Kumbartzki; L. Lu; Allison Lung; Pete Markowitz; Justin McIntyre; David Meekins; F. Merchez; Joseph Mitchell; R. Mohring; S. Mtingwa; H. Mrktchyan; D. Pitz; Liming Qin; Ronald Ransome; J.-S. R'eal; Philip Roos; Paul Rutt; Reyad Sawafta; Stepan Stepanyan; Raphael Tieulent; E. Tomasi-Gustafsson; William Turchinetz; K. Vansyoc; J. Volmer; E. Voutier; Claude Williamson; Stephen Wood; Chen Yan; Jianguo Zhao; W. Zhao


    A rigorous extraction of the deuteron charge form factors from tensor polarization data in elastic electron-deuteron scattering, at given values of the 4-momentum transfer, is presented. Then the world data for elastic electron-deuteron scattering is used to parameterize, in three different ways, the three electromagnetic form factors of the deuteron in the 4-momentum transfer range 0-7 fm. This procedure is made possible with the advent of recent polarization measurements. The parameterizations allow a phenomenological characterization of the deuteron electromagnetic structure. They can be used to remove ambiguities in the form factors extraction from future polarization data

  5. Towards a Kantian Phenomenology of Hope


    Beyleveld, D.; Ziche, Paul


    The aim of this paper is to examine the extent to which Kant’s Critique of the Power of Judgment (CPoJ) can be, or otherwise ought to be, regarded as a transcendental phenomenology of hope. Kant states repeatedly that CPoJ mediates between the first two Critiques, or between the theoretical knowledge we arrive at on the basis of understanding and reason’s foundational role for practical philosophy. In other words, exercising the power of judgment is implicated whenever we try to bring togethe...

  6. Phenomenology and treatment of behavioural addictions. (United States)

    Grant, Jon E; Schreiber, Liana R N; Odlaug, Brian L


    Behavioural addictions are characterized by an inability to resist an urge or drive resulting in actions that are harmful to oneself or others. Behavioural addictions share characteristics with substance and alcohol abuse, and in areas such as natural history, phenomenology, and adverse consequences. Behavioural addictions include pathological gambling, kleptomania, pyromania, compulsive buying, compulsive sexual behaviour, Internet addiction, and binge eating disorder. Few studies have examined the efficacy of pharmacological and psychological treatment for the various behavioural addictions, and therefore, currently, no treatment recommendations can be made.

  7. Phenomenology of Supersymmetric Large Extra Dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Hewett, JoAnne L.


    We study the phenomenology of a supersymmetric bulk in the scenario of large extra dimensions. The virtual exchange of gravitino KK states in selectron pair production in polarized e{sup +}e{sup -} collisions is examined. The leading order operator for this exchange is dimension six, in contrast to that of graviton KK exchange which induces a dimension eight operator at lowest order. Some kinematic distributions for selectron production are presented. These processes yield an enormous sensitivity to the fundamental higher dimensional Planck scale.

  8. Phenomenology of chiral damping in noncentrosymmetric magnets

    KAUST Repository

    Akosa, Collins Ashu


    A phenomenology of magnetic chiral damping is proposed in the context of magnetic materials lacking inversion symmetry. We show that the magnetic damping tensor acquires a component linear in magnetization gradient in the form of Lifshitz invariants. We propose different microscopic mechanisms that can produce such a damping in ferromagnetic metals, among which local spin pumping in the presence of an anomalous Hall effect and an effective “s-d” Dzyaloshinskii-Moriya antisymmetric exchange. The implication of this chiral damping in terms of domain-wall motion is investigated in the flow and creep regimes.

  9. Disoriented chiral condensate: Theory and phenomenology

    International Nuclear Information System (INIS)

    Bjorken, J.D.


    These notes are an abbreviated version of lectures given at the 1997 Zakopane School. They contain two topics. The first is a description in elementary terms of the basic ideas underlying the speculative hypothesis that pieces of strong-interaction vacuum with a rotated chiral order parameter, disoriented chiral condensate or DCC, might be produced in high energy elementary particle collisions. The second topic is a discussion of the phenomenological techniques which may be applied to data in order to experimentally search for the existence of DCC

  10. Quantum supergravity, supergravity anomalies and string phenomenology

    Energy Technology Data Exchange (ETDEWEB)

    Gaillard, Mary K., E-mail:


    I discuss the role of quantum effects in the phenomenology of effective supergravity theories from compactification of the weakly coupled heterotic string. An accurate incorporation of these effects requires a regularization procedure that respects local supersymmetry and BRST invariance and that retains information associated with the cut-off scale, which has physical meaning in an effective theory. I briefly outline the Pauli–Villars regularization procedure, describe some applications, and comment on what remains to be done to fully define the effective quantum field theory.

  11. Hegel's Path Toward the Phenomenology of Mind

    Directory of Open Access Journals (Sweden)

    Carlos Rendón


    Full Text Available This paper seeks to reconstruct the possible steps followed by Hegel toward his Phenomenology of Mind. Taking into account the historical variants of the process, this paper will try to determine the meaning and the relationship between these variants and the philosophical consolidation of the book. The development of the text does not follow a linear evolution, but rather shows unexpected but comprehensible continuities and ruptures. These contingencies will be decisive for some of the main formulations of the book itself, showing it as a “result” in the more Hegelian sense of the word: as that which is intrinsically linked to its becoming.

  12. Melanie Klein's metapsychology: phenomenological and mechanistic perspective. (United States)

    Mackay, N


    Freud's metapsychology is the subject of an important debate. This is over whether psychoanalysis is best construed as a science of the natural science type or as a special human science. The same debate applies to Melanie Klein's work. In Klein's metapsychology are two different and incompatible models of explanation. One is taken over from Freud's structural theory and appears to be similarly mechanistic. The other is clinically based and phenomenological. These two are discussed with special reference to the concepts of "phantasy" and "internal object".

  13. Phenomenological community and integrative social agency: Critique of a phenomenological concept of inter-subjectivity

    Directory of Open Access Journals (Sweden)

    Bagi Zsolt


    Full Text Available The term „phenomenological community“ is not among the most well-known concepts of phenomenology. It was used by Marc Richir referring to Merleau-Ponty’s concept of „natural“ community. The paper examines this concept from the point of view of social philosophy. It analyses its relevance in the context of a post-Hegelian philosophy of inter-subjectivity. The community conceived this way is origin and result at the same time, giving rise to a theory of a historically grounded formation of a previously not given and heterogeneous communicative integration; moreover, social mediation defining the subject of action is an open, non-totalizing process, which makes it possible to conceptualize an integrative action that does not neutralize the heterogeneity of the contemporary society. The theory of the phenomenological community is the ontology of a disintegrated but common world. Social action never happens on the basis of chaos but of the inter-subjective world, thus it can provide a new basis for such an action. On the other hand the „phenomenological community“ is essentially a form of the „passive synthesis“ thus it is unable to provide foundation for a unifying action, the only possibility for an authentic integration (a non-representative form of social integration. Thus it necessitates a critique.

  14. Behavioural phenotypes and special educational needs: is aetiology important in the classroom? (United States)

    Reilly, C


    A number of genetic conditions with associated intellectual disability and/or special educational needs have increasingly well-defined behavioural phenotypes. Thus, the concept of 'behavioural phenotype' and aetiology of intellectual disability may be important with regard to school-based interventions. The evidence for distinctive cognitive and behavioural aspects of five of the most common genetic syndromes (Down syndrome, fragile X syndrome, Williams syndrome, Prader-Willi syndrome and velo-cardio-facial syndrome) associated with special educational needs is reviewed with respect to key studies and findings. The possible utility of aetiology-related interventions in education is discussed with reference to arguments for and against such approaches with respect to published guidelines and published research. Behavioural phenotypes are probabilistic and many children with a specific genetic syndrome will share commonalities with other children with other genetic syndromes and within syndrome variability is not uncommon. There is evidence that teachers and parents have limited knowledge of aspects of the proposed cognitive and behaviour profiles associated with the reviewed syndromes. While there are published guidelines in the area of learning and behaviour for each of the five reviewed syndromes there is a limited amount of evidence of the efficacy of such approaches in school settings. It is likely that knowing the aetiology of a child's special educational needs will be helpful for staff who work in school settings in relation to cognitive and behavioural implications. However, how such knowledge might inform teaching practice or behavioural interventions has not been studied. A model is proposed that might help inform educators about the possible role of aetiology in the classroom. © 2012 The Author. Journal of Intellectual Disability Research © 2012 Blackwell Publishing Ltd.

  15. [Nature meets nurture: the importance of epigenetics for the aetiology of psychiatric diseases]. (United States)

    Buchholz, V; Kotsiari, A; Bleich, S; Frieling, H


    A successful therapy requires an understanding and investigation of the aetiology of a disease. Psychiatric diseases represent a special challenge, because environmental factors may play a crucial role in their development as well as possible physiological and genetic causes. Therefore, epigenetics has established itself to be a branch of research that studies the effect of environmental factors on the development of psychiatric diseases, leading to promising new approaches for diagnosis and therapy. © Georg Thieme Verlag KG Stuttgart · New York.

  16. Fractures in indigenous compared to non-indigenous populations: A systematic review of rates and aetiology

    Directory of Open Access Journals (Sweden)

    Sharon L. Brennan-Olsen


    Conclusions: The observed paucity of data and suggestion of continent-specific differences indicate an urgent need for further research regarding indigenous status and fracture epidemiology and aetiology. Our findings also have implications for communities, governments and healthcare professionals to enhance the prevention of trauma-related fractures in indigenous persons, and an increased focus on modifiable lifestyle behaviours to prevent osteoporotic fractures in all populations.

  17. Posterior Laryngitis- Aetiology,Treatment and Health-Related Quality of Life


    Pendleton, Hillevi


    Posterior laryngitis (PL) is defined as an inflammation involving the posterior part of the glottal region in conjunction with symptoms. The cause is multifactorial. The aims of the work presented in this thesis were to examine symptoms, physical signs, different aetiologies and health-related quality of life (HRQOL) in patients with PL and/or oesophageal dysmotility. In paper I, a group of patients diagnosed as having PL were examined, treated and followed, to determine whether follo...


    Directory of Open Access Journals (Sweden)

    Chandrakala Guruprasad Yelwanti


    Full Text Available BACKGROUND The heart failure is a worldwide health problem with ever increasing proportion and is a major health problem in elderly persons. It has many aetiological factors. It is one of the most frequently encountered illnesses in day-to-day practice and most common cause of death in patients with cardiac disease. This study was done to determine the age and sex distribution and to evaluate clinical features and aetiological factors in patients admitted with heart failure at Khaja Banda Nawaz Teaching and General Hospital, Gulbarga, on the basis of clinical assessment, electrocardiography and echocardiography. MATERIALS AND METHODS A prospective study was done in Department of General Medicine at Khaja Banda Nawaz Teaching and General Hospital, Gulbarga, from January 2015 to June 2016 on patients with heart failure to determine the clinical and aetiological profile. A total of 100 cases above the age of 20 years were included in the study. The patients below the age of 20 years and known cases of congenital heart disease were excluded. RESULTS Out of 100 patients, the heart failure was seen more commonly in men than in women between the age groups of 46-65 years of age. Breathlessness was the most common presentation followed by pedal oedema, orthopnoea, etc. In our study, the primary aetiology for heart failure was found to be coronary artery disease (47% followed by dilated cardiomyopathy (20%, hypertension (14%, rheumatic heart disease (7%, anaemia (6%, cor pulmonale (4% and others (2%. Dyslipidaemia was the common risk factor followed by obesity and smoking. CONCLUSION The heart failure commonly occurs in elderly people and the incidence was higher in men than in women. The commonest presentation was breathlessness followed by pedal oedema. The commonest cause of heart failure was coronary artery disease followed by dilated cardiomyopathy and then hypertension combined with ischaemic heart disease.

  19. New data on aetiology of nodular gill disease in rainbow trout, Oncorhynchus mykiss

    Czech Academy of Sciences Publication Activity Database

    Dyková, Iva; Kostka, Martin; Wortberg, F.; Nardy, E.; Pecková, Hana


    Roč. 57, č. 3 (2010), s. 157-163 ISSN 0015-5683 R&D Projects: GA ČR GA524/09/0137; GA MŠk LC522 Institutional research plan: CEZ:AV0Z60220518 Keywords : nodular gill disease * aetiological study * amoebae * Naegleria sp. * fish diseases * aquaculture * Oncorhynchus mykiss Subject RIV: GJ - Animal Vermins ; Diseases, Veterinary Medicine Impact factor: 1.533, year: 2010

  20. Theories of urinary incontinence causation: aetiological descriptions by sub-Saharan African women. (United States)

    Morhason-Bello, Imran O; Ojengbede, Oladosu A; Adedokun, Babatunde O; Okonkwo, Ngozi S; Kolade, Charles


    To describe the perceived causes of urinary incontinence (UI) and factors associated with awareness of causes of UI among women in the community. Secondary analysis of data extracted from the Ibadan Urinary Incontinence Household Survey (IUIHS), a multi-stage community survey conducted among 5001 women in Nigeria. The mean age was 34.8 years (SD=14.2). The majority had at least secondary education and were currently married. Within this population, 13% had ever leaked urine. On their perception of possible aetiological factors of UI, 20.5% mentioned pelvic floor or bladder-related causes such as stress incontinence triggers and bladder problems; 14.6% mentioned uncontrollable factors such as medical comorbidity, age and prior surgery; 8.8% attributed the cause to being female; and 6.8% mentioned sex-related factors. Multiple logistic regression analysis revealed significantly lower odds of awareness of the aetiology of urinary incontinence among women aged less than 30 years, those with lower level of education, rural women, those with five or more children and women without history of urine leakage. The study shows a low level of awareness of possible cause of UI amongst women surveyed. We recommend health education and mobilization of women on the right aetiological factors of UI. Crown Copyright © 2012. Published by Elsevier Ireland Ltd. All rights reserved.

  1. Aetiology of maxillofacial fractures: a review of published studies during the last 30 years. (United States)

    Boffano, Paolo; Kommers, Sofie C; Karagozoglu, K Hakki; Forouzanfar, Tymour


    The epidemiology of facial trauma may vary widely across countries (and even within the same country), and is dependent on several cultural and socioeconomic factors. We know of few reviews of published reports that have considered the sex distribution and aetiology of maxillofacial trauma throughout the world. The aim of this review was to discuss these aspects as they have been presented in papers published during the last 30 years. We made a systematic review of papers about the epidemiology of maxillofacial trauma that were published between January 1980 and December 2013 and identified 69 studies from Africa (n=9), North America and Brazil (n=6), Asia (n=36), Europe (n=16), and Oceania (n=2). In all the studies men outnumbered women, the ratio usually being more than 2:1. In American, African, and Asian studies road traffic crashes were the predominant cause. In European studies the aetiology varied, with assaults and road traffic crashes being the most important factors. In Oceania assaults were the most important. A comparison of the incidence of maxillofacial trauma of different countries together with a knowledge of different laws (seat belts for drivers, helmets for motocyclists, speed limits, and protection worn during sports and at work) is crucial to allow for improvement in several countries. To our knowledge this paper is the first attempt to study and compare the aetiologies of maxillofacial trauma. Copyright © 2014 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  2. An investigation into febrile illnesses of unknown aetiology in Wipim, Papua New Guinea. (United States)

    Bande, Grace; Hetzel, Manuel W; Iga, Jonah; Barnadas, Celine; Mueller, Ivo; Siba, Peter M; Horwood, Paul F


    In Papua New Guinea the aetiology of febrile illnesses remains poorly characterized, mostly due to poor diagnostic facilities and the inaccessibility of much of the rural areas of the country. We investigated the aetiological agents of febrile illnesses for 136 people presenting to Wipim Health Centre in Western Province, Papua New Guinea. Arboviral and rickettsial real-time polymerase chain reaction (PCR) assays, malaria blood smears and a malaria PCR test were used to identify pathogens associated with a history of fever. In 13% (n = 18) of cases an aetiological agent was identified. Dengue virus type 1 was detected in 11% (n = 15) of the samples tested and malaria in 2% (n = 3). None of the other arboviral or rickettsial pathogens tested for were detected in any of the samples. Although dengue viruses have been identified in Papua New Guinea using serological methods, this study represents the first direct detection of dengue in the country. The detection of malaria, on the other hand, was surprisingly low considering the previous notion that this was a hyperendemic region of Papua New Guinea.

  3. Non-traumatic cortical subarachnoid haemorrhage: diagnostic work-up and aetiological background

    Energy Technology Data Exchange (ETDEWEB)

    Spitzer, C.; Kosinski, C.M. [University Hospital of RWTH Aachen, Department of Neurology, Aachen (Germany); Mull, M. [University Hospital of RWTH Aachen, Department of Neuroradiology, Aachen (Germany); Rohde, V. [University Hospital of RWTH Aachen, Department of Neurosurgery, Aachen (Germany)


    Only 15% of all subarachnoid haemorrhages (SAHs) are not of aneurysmal origin. Among those, circumscribed SAHs along the cortical convexity are rare and have only been described in singular case reports so far. Here, we present a collection of 12 cases of SAH along the convexity, of non-traumatic origin. Over a period of 10 years, 12 cases of circumscribed SAH along the convexity were identified at our clinic. The clinical presentations, neuroradiological SAH characteristics, further diagnostic work-up to identify the underlying aetiologies, the therapy and clinical outcome were analysed. The patients' chief complaints were unspecific cephalgia, focal or generalised seizures and focal neurological deficits. Typical signs of basal SAH, such as nuchal rigidity, thunderclap-headache or alteration of consciousness, were rare. Magnetic resonance imaging (MRI) and digital subtraction angiography (DSA) revealed different aetiologies, namely postpartal posterior encephalopathy (three), cerebral vasculitis (two), dural sinus thrombosis (two), cortical venous thrombosis (one), intracerebral abscesses (one) and cerebral cavernoma (one). Two cases remained unresolved. Treatment of the underlying disease and symptomatic medication led to good clinical outcome in almost all cases. On the basis of these findings, we demonstrate that the clinical presentation, localisation and aetiology of cortical SAH differ clearly from other SAHs. A diagnostic work-up with MRI and eventually DSA is essential. Mostly, the causative disease can be identified, and specific treatment allows a favourable outcome. (orig.)

  4. Mental disorders of known aetiology and precision medicine in psychiatry: a promising but neglected alliance. (United States)

    Fraguas, D; Díaz-Caneja, C M; State, M W; O'Donovan, M C; Gur, R E; Arango, C


    Personalized or precision medicine is predicated on the assumption that the average response to treatment is not necessarily representative of the response of each individual. A commitment to personalized medicine demands an effort to bring evidence-based medicine and personalized medicine closer together. The use of relatively homogeneous groups, defined using a priori criteria, may constitute a promising initial step for developing more accurate risk-prediction models with which to advance the development of personalized evidence-based medicine approaches to heterogeneous syndromes such as schizophrenia. However, this can lead to a paradoxical situation in the field of psychiatry. Since there has been a tendency to loosely define psychiatric disorders as ones without a known aetiology, the discovery of an aetiology for psychiatric syndromes (e.g. 22q11.2 deletion syndrome in some cases of schizophrenia), while offering a path toward more precise treatments, may also lead to their reclassification away from psychiatry. We contend that psychiatric disorders with a known aetiology should not be removed from the field of psychiatry. This knowledge should be used instead to guide treatment, inasmuch as psychotherapies, pharmacotherapies and other treatments can all be valid approaches to mental disorders. The translation of the personalized clinical approach inherent to psychiatry into evidence-based precision medicine can lead to the development of novel treatment options for mental disorders and improve outcomes.

  5. Molar incisor hypomineralization: a study of aetiological factors in a group of UK children. (United States)

    Whatling, Rosemary; Fearne, Janice M


    The objectives were to investigate the aetiology of molar incisor hypomineralization (MIH), and to discuss previously published studies. One hundred and nine children attending the Department of Paediatric Dentistry at the Royal London Hospital were included in the study: 57 children with MIH and 52 controls. Their mothers completed a medical history interview. No significant associations were found with MIH and delivery and birth complications, breastfeeding, immunization history, other illnesses and allergies, general anaesthetics, fluoride history, and trauma or abscesses affecting the primary predecessors. A family history of enamel defects was more commonly reported for MIH children, but the association was not statistically significant. However, MIH was significantly more common among those whose mothers had experienced problems during pregnancy (P = 0.025), those who had chickenpox between the ages of 3 and 3.99 (P = 0.047), and those for whom amoxycillin was the only antibiotic they had received (P = 0.028). The aetiology of MIH remains unclear, and this study questions whether it is because of a lone aetiological insult. This study recommends further research looking at the links with chickenpox occurring around the third year of life and amoxycillin.

  6. Aetiology and types of neonatal seizures presenting at ayub teaching hospital abbottabad

    International Nuclear Information System (INIS)

    Najeeb, S.; Qureshi, A.M.; Rehman, A.U.; Ahmed, F.; Shah, S.


    Background: Neonatal seizures (NS) affect approximately 1% of neonates. Clonic, tonic, myoclonic and subtle seizures are the common types. Birth asphyxia, sepsis, metabolic derangements, intracranial bleed, kernicterus, tetanus and 5th day fits are the common aetiologies. This study was planned to evaluate the types and causes of neonatal seizures. Methods: It was a descriptive case series conducted at Ayub Teaching Hospital, Abbottabad from 12th December 2006 to 25th September 2007 on neonates having seizures. Serum chemistry, blood counts, cerebrospinal fluid examination and cranial ultrasound were done in all patients. Blood culture, renal and liver function tests, computerised tomography scan, metabolic and septic screening was done in selected patients. Descriptive statistics were applied for analysis. Results: Tonic clonic seizure was the commonest type (28%) followed by multi-focal clonic, and focal tonic seizures (25% each). Birth asphyxia was found to be the main aetiology (46%). Conclusion: Tonic clonic seizure was the commonest type and birth asphyxia the main aetiology identified in the majority of neonatal seizures. (author)

  7. Hermeneutical Phenomenology of Performance. Based on the hermeneutical phenomenology of Hans-Georg Gadamer and Truth and Method


    Ghasemi, Samira


    The main subject of my MA thesis is the relationship between art, artist and the audience in the process of comprehension and creation of the meaning. I try to understand how a piece of art is created and interpreted. The thesis that I would like to defend in this research is the application of the hermeneutical phenomenology of Hans Georg Gadamer to performance. Key Words Art- Performance- Meaning- Phenomenology- Hermeneutics- Hermeneutical phenomenology- Schleiermacher- Heidegger- Darstellu...

  8. Humanising Phenomenological analysis: using focus groups, food, and drink to collect data for Descriptive and Interpretative Phenomenological Analysis (IPA)


    Beer, Sean


    Aim To explore the use of focus groups, specifically those involving a meal, as a method for phenomenological data collection. Method Six focus groups were conducted, in order to examine participants’ perceptions of the authenticity of food. The data were analysed using Descriptive, and Interpretative Phenomenological Analysis (IPA). This is somewhat controversial as many commentators maintain that focus groups cannot be used to collect phenomenological data, however, Smith (2004, p. 50) main...

  9. Transformations through Proximity Flying: A Phenomenological Investigation

    Directory of Open Access Journals (Sweden)

    Maria Holmbom


    Full Text Available Participation in extreme sports has been linked to personal transformations in everyday life. Descriptions of lived experience resulting from transformative experiences are limited. Proximity flying, a relatively new discipline involving BASE jumping with a wingsuit where participants fly close to solid structures, is arguably one of the most extreme of extreme sports. The aim of this paper, part of a larger phenomenological study on the lived experience of proximity flying, is to explicate the ways in which participating in proximity flying influences the everyday lives of participants. Interpretative phenomenological analysis was used to explicate the lived experience of six proximity pilots. An analysis of interview transcripts revealed three significant themes describing the lived experience of participants. First, experiences of change were described as positive and skills developed through proximity flying were transferable into everyday life. Second, transformative experiences were considered fundamental to participants’ perspectives on life. Third, experience of transformation influenced their sense of personal identity and facilitated flourishing in other aspects of everyday life. Participants were clear that their experiences in proximity flying facilitated a profound process of transformation which manifest as changes in everyday capabilities and behaviors, values and sense of identity.

  10. Beyond Empathy. Phenomenological Approaches to Intersubjectivity

    Directory of Open Access Journals (Sweden)

    Dan Zahavi


    Full Text Available Drawing on the work of Scheler, Heidegger, Merleau-Ponty, Husserl and Sartre, this article presents an overview of some of the diverse approaches to intersubjectivity that can be found in the phenomenological tradition. Starting with a brief description of Scheler’s criticism of the argument from analogy, the article continues by showing that the phenomenological analyses of intersubjectivity involve much more than a ‘solution’ to the ‘traditional’ problem of other minds. Intersubjectivity doesn’t merely concern concrete faceto-face encounters between individuals. It is also something that is at play in simple perception, in tool-use, in emotions, drives and different types of self-awareness. Ultimately, the phenomenologists would argue that a treatment of intersubjectivity requires a simultaneous analysis of the relationship between subjectivity and world. It is not possible simply to insert intersubjectivity somewhere within an already established ontology; rather, the three regions ‘self’, ‘others’, and ‘world’ belong together; they reciprocally illuminate one another, and can only be understood in their interconnection. 

  11. [Phenomenological study of infertile women with obesity]. (United States)

    Arranz-Lara, Lilia; Martínez-Lemus, Hugo; Ruíz-Ornelas, Jaime; Sauceda-González, Luciano; Pimentel, Elizabeth; Anguiano, Norma; Sondón, Zoé; Cedillo, Javier; Chávez, Alvaro; Regalado, Miguel Angel; Moreno, Daniel


    Obesity is a condition strongly associated with polycystic ovary and other conditions that interfere with or complicate the treatment of assisted reproduction. To examine, from a phenomenological point of view, the perception of infertile women obesity problem before undergoing assisted reproduction treatment. This analysis should help to design a psychotherapeutic strategy focused on this problem. One hundred patients with infertility, with a BMI equal to or greater than 30, candidates for assisted reproductive treatments in the service of Human Reproduction, Centro Médico Nacional 20 de Noviembre, ISSSTE. The phenomenological qualitative analysis was performed in 72 women who agreed to be interviewed in depth. The phenomenon is to study obesity in infertile women candidates for assisted reproduction treatment. Obese infertile women subject to assisted reproduction treatment perceive their difficulty losing weight is closely associated with infertility. Most patients had social feelings of worthlessness, sadness, worthlessness, and family rejection. The inability to obtain a steady weight loss is regarded as a minor frustration that sterility. It is very important to perform intensive, multidisciplinary labor, which is focused on concepts associated with psychological distress, such as: management of depression by sterility, control of anxiety and stress, control of social pressures and management of the illusion of motherhood. Also rely on specialists of eating habits and exercise.

  12. Racism: On the phenomenology of embodied desocialization. (United States)

    Staudigl, Michael

    This paper addresses racism from a phenomenological viewpoint. Its main task is, ultimately, to show that racism as a process of "negative socialization" does not amount to a contingent deficiency that simply disappears under the conditions of a fully integrated society. In other words, I suspect that racism does not only indicate a lack of integration, solidarity, responsibility, recognition, etc.; rather, that it is, in its extraordinary negativity, a socially constitutive phenomenon per se . After suggesting phenomenology's potential to tackle the question of racism, I will focus on the experiential oppressiveness of racism, i.e., the ways in which it affects its victims' lived experiences, in transforming their habitual ways of life and, finally, their subjectivities. My major thesis is that racism works via both inter-kinaesthetically as well as symbolically inflicted distortions of the victim's body schema. As such a process of "negative socialization," racism, however, influences the embodied self-conception of the oppressor, who finds himself compelled to adhere to some kind of invisible norm such as, e.g., "whiteness."

  13. Destruction as a Step in Heidegger's Phenomenology

    Directory of Open Access Journals (Sweden)

    M.J Safian


    Full Text Available One of the most controversial issues in Heidegger’s philosophy is his claim that western philosophy tradition has overlooked the issue of Being. Heidegger’s attempt is to reveal the origins of this negligence by means of destruction. However, it seems that through such claim Heidegger aims to destroy and disvalue this tradition. In addition to defining and explaining destruction, our purpose in this article is to show that Heidegger’s goal is not to destroy the tradition of philosophy but the term destruction refers to a process which is a step in Heidegger’s phenomenology by means of which one can conceive and perceive Being better because only through such destruction ontology can fully assure itself in a phenomenological way of the genuine character of its concepts. The necessity of doing destruction in Heidegger’s thought has also been discussed and his persistence on it has been shown in two of his works, one belongs to early and another to later Heidegger.

  14. Disorientations: John Singer Sargent and Queer Phenomenology

    Directory of Open Access Journals (Sweden)

    Anne Pasek


    Full Text Available Art history has long struggled to find a method to account for the diverse expressions of queer desire across the heterogeneous landscape of history. While there has been a surge of research on the lives, artworks, and audiences of artists that trouble the heterosexual norm, the wider impact of this scholarship is often limited to singular biographies. Following the call for greater self-reflexivity and acknowledgement of difference in queer theory and phenomenological approaches to art history, the additive goals of gay and lesbian scholarship with its political investment in strategies of representation can be brought into scrutiny. To this end, a critical historiographical review of gay and lesbian art history is undertaken and a queer phenomenological method is presented as a new means forward. Applied to the work of John Singer Sargent, it is argued that a focus on the spatial orientation of bodies in his album of male nudes provides a more nuanced and ethical account of the queer than a focus on identity and identifications.

  15. Particle Phenomenology of Compact Extra Dimensions

    International Nuclear Information System (INIS)

    Melbeus, Henrik


    This thesis is an investigation of the subject of extra dimensions in particle physics. In recent years, there has been a large interest in this subject. In particular, a number of models have been suggested that provide solutions to some of the problem with the current Standard Model of particle physics. These models typically give rise to experimental signatures around the TeV energy scale, which means that they could be tested in the next generation of high-energy experiments, such as the LHC. Among the most important of these models are the universal extra dimensions model, the large extra dimensions model by Arkani-Hamed, Dimopolous, and Dvali, and models where right-handed neutrinos propagate in the extra dimensions. In the thesis, we study phenomenological aspects of these models, or simple modifications of them. In particular, we focus on Kaluza-Klein dark matter in universal extra dimensions models, different aspects of neutrino physics in higher dimensions, and collider phenomenology of extra dimensions. In addition, we consider consequences of the enhanced renormalization group running of physical parameters in higher-dimensional models

  16. Staggered Pairing Phenomenology for UBe_13 (United States)

    Martisovits, V.; Cox, D. L.


    The staggered-pairing Ginzburg-Landau phenomenology based upon Cooper pairs with a finite center-of-mass momentum was previously applied to the hexagonal heavy-fermion superconductors UPt_3,(R. Heid, Ya. B. Bazaliy, V. Martisovits, and D. L. Cox, Phys. Rev. Lett. 74), 2571 (1995). UPd_2Al_3, and UNi_2Al_3.(V. Martisovits and D. L. Cox (to be published); Report No. cond-mat/9706245.) Here we apply this phenomenology to study the cubic heavy-fermion superconductor UBe_13. We find the momentum of Cooper pairs to be at X points on the Brillouin-zone boundary and identify a three-component superconducting order parameter transforming as an X-point irreducible representation of the space group. Minimizing the free energy, we find possible superconducting phases and the upper critical field H_c2. We investigate coupling to strain fields and the possibility of magnetic order and charge-density waves induced by superconductivity. To explain multiple superconducting phases in the temperature-thorium-concentration phase diagram of U_1-xTh_xBe_13, we model the influence of thorium in terms of random tetragonal strain fields.

  17. Phenomenology of Low Quantum Gravity Scale Models

    CERN Document Server

    Benakli, Karim


    We study some phenomenological implications of models where the scale of quantum gravity effects lies much below the four-dimensional Planck scale. These models arise from M-theory vacua where either the internal space volume is large or the string coupling is very small. We provide a critical analysis of ways to unify electroweak, strong and gravitational interactions in M-theory. We discuss the relations between different scales in two M-vacua: Type I strings and Ho\\v rava--Witten supergravity models. The latter allows possibilities for an eleven-dimensional scale at TeV energies with one large dimension below separating our four-dimensional world from a hidden one. Different mechanisms for breaking supersymmetry (gravity mediated, gauge mediated and Scherk-Schwarz mechanisms) are discussed in this framework. Some phenomenological issues such as dark matter (with masses that may vary in time), origin of neutrino masses and axion scale are discussed. We suggest that these are indications that the string scal...

  18. Choosing phenomenology as a guiding philosophy for nursing research. (United States)

    Matua, Gerald Amandu


    To provide an overview of important methodological considerations that nurse researchers need to adhere to when choosing phenomenology as a guiding philosophy and research method. Phenomenology is a major philosophy and research method in the humanities, human sciences and arts disciplines with a central goal of describing people's experiences. However, many nurse researchers continue to grapple with methodological issues related to their choice of phenomenological method. The author conducted online and manual searches of relevant research books and electronic databases. Using an integrative method, peer-reviewed research and discussion papers published between January 1990 and December 2011 and listed in the CINAHL, Science Direct, PubMed and Google Scholar databases were reviewed. In addition, textbooks that addressed research methodologies such as phenomenology were used. Although phenomenology is widely used today to broaden understanding of human phenomena relevant to nursing practice, nurse researchers often fail to adhere to acceptable scientific and phenomenological standards. Cognisant of these challenges, researchers are expected to indicate in their work the focus of their investigations, designs, and approaches to collecting and analysing data. They are also expected to present their findings in an evocative and expressive manner. Choosing phenomenology requires researchers to understand it as a philosophy, including basic assumptions and tenets of phenomenology as a research method. This awareness enables researchers, especially novices, to make important methodological decisions, particularly those necessary to indicate the study's scientific rigour and phenomenological validity. This paper adds to the discussion of phenomenology as a guiding philosophy for nursing research. It aims to guide new researchers on important methodological decisions they need to make to safeguard their study's scientific rigour and phenomenological validity.

  19. Role of medical history and medication use in the aetiology of upper aerodigestive tract cancers in Europe: the ARCAGE study.

    LENUS (Irish Health Repository)

    Macfarlane, T V


    The study aimed to investigate the role of medical history (skin warts, Candida albicans, herpetic lesions, heartburn, regurgitation) and medication use (for heartburn; for regurgitation; aspirin) in the aetiology of upper aerodigestive tract (UADT) cancer.

  20. Living With Chronic Lower Pulmonary Disease: Disruptions of the Embodied Phenomenological Self. (United States)

    Pooler, Charlotte


    In this article, I present a phenomenological study of individuals' experiences of living with moderate to very severe chronic lower pulmonary disease (chronic obstructive pulmonary disease, asthma, or both). Phenomenology is a philosophy, distinct from descriptive or thematic research, which is useful as a foundation for scientific inquiry. In this study, I used the lens of Merleau-Ponty to understand and interpret participants' experiences of living with pulmonary disease, and the approach of van Manen for analysis. I conclude that in chronic pulmonary disease, awareness of breathing and the body is experienced in the sounds, sensations, and signals of breathing and the body, and in the experiences of the body-in-the-world. Central themes of being-in-the-world from the study describe the disruption of the embodied phenomenological self: Participants experienced slowing down, doing less, and having to stop due to shortness of breath. Both chronic and acute dyspnea were prevalent and the taken-for-granted aspects of daily activities were disrupted. Findings of this study have implications for public and patient education, and opportunities for integration of experiential aspects within nursing education and practice.

  1. Crosscurrents: Phenomenology and Fond Memories of Bill Kell. (United States)

    Beere, Don

    The author clarifies, in a memorium address, how he experiences phenomenological ideas and how they apply to therapy and supervision. The phenomenological method called "epokhe" is defined as the "suspension of preconceptions" or "judgments" concerning a series of events, and, as a result, the achievement of greater clarity in experiencing those…

  2. Women, Anger, and Aggression: An Interpretative Phenomenological Analysis (United States)

    Eatough, Virginia; Smith, Jonathan A.; Shaw, Rachel


    This study reports a qualitative phenomenological investigation of anger and anger-related aggression in the context of the lives of individual women. Semistructured interviews with five women are analyzed using interpretative phenomenological analysis. This inductive approach aims to capture the richness and complexity of the lived experience of…

  3. Notes Towards a Phenomenological Reading of Lacan | Kemp ...

    African Journals Online (AJOL)

    Phenomenological psychotherapy, while critiquing psychoanalytic theories, has always sought to draw on and be inspired by these (and other) approaches. To read psychoanalysis through the lens of existential-phenomenology opens, deepens and perhaps even rehabilitates this body of work. In this paper, the work of the ...

  4. Researching Embodiment in Movement Contexts: A Phenomenological Approach (United States)

    Standal, Oyvind F.; Engelsrud, Gunn


    This article takes a phenomenological approach to understanding embodiment in relation to teaching and learning taking place in movement contexts. Recently a number of studies have pointed to the potential that phenomenology has to understand the meanings and experiences of moving subjects. By presenting two examples of our own work on embodied…

  5. Interpretive and Critical Phenomenological Crime Studies: A Model Design (United States)

    Miner-Romanoff, Karen


    The critical and interpretive phenomenological approach is underutilized in the study of crime. This commentary describes this approach, guided by the question, "Why are interpretive phenomenological methods appropriate for qualitative research in criminology?" Therefore, the purpose of this paper is to describe a model of the interpretive…

  6. Merleau-Ponty's Phenomenology of Language and General Semantics. (United States)

    Lapointe, Francois H.

    A survey of Maurice Merleau-Ponty's views on the phenomenology of language yields insight into the basic semiotic nature of language. Merleau-ponty's conceptions stand in opposition to Saussure's linguistic postulations and Korzybski's scientism. That is, if language is studied phenomenologically, the acts of speech and gesture take on greater…

  7. Effects of Language Spread on a People' Phenomenology: The ...

    African Journals Online (AJOL)

    Effects of Language Spread on a People' Phenomenology: The Case of Sheng' in Kenya. ... Journal of Language, Technology & Entrepreneurship in Africa ... In this paper, I will first discuss the distribution and spread of Sheng' in Kenya, and secondly, I will show the effects of Sheng' on its speakers' phenomenology, ...

  8. Difficulties Encountered in the Application of the Phenomenological ...

    African Journals Online (AJOL)

    While it is heartening to see that more researchers in the field of the social sciences are using some version of the phenomenological method, it is also disappointing to see that very often some of the steps employed do not follow phenomenological logic. In this paper, several dissertations are reviewed in order to point out ...

  9. Phenomenology of non-universal gaugino masses and implications ...

    Indian Academy of Sciences (India)

    We study the implications of such non-universal gaugino masses for the composition of the lightest neutralino in supersymmetric (SUSY) theories based on (5) gauge group. We also consider the phenomenological implications of non-universal gaugino masses for the phenomenology of Higgs bosons in the context of ...

  10. Phenomenological dynamics: From Navier–Stokes to chiral granular ...

    Indian Academy of Sciences (India)

    As a final example of the phenomenological approach to slow dynamical processes, it discusses the dynamics of ... derive phenomenological equations governing the slow dynamics of any equilibrium system given its .... τ, then these modes are well-defined; if on the other hand τ⊥ and τ|| are of order τ, there may be many ...

  11. Examining the Lived World: The Place of Phenomenology in ...

    African Journals Online (AJOL)

    This paper aims to explore the validity of phenomenology in the psychiatric setting. The phenomenological method - as a mode of research, a method of engagement between self and other, and a framework for approaching what it means to know - has found a legitimate home in therapeutic practice. Over the last century, ...

  12. Phenomenology and cosmology of weakly coupled string theory

    International Nuclear Information System (INIS)

    Gaillard, Mary K.


    The weakly coupled vacuum of E 8 (circle t imes) E 8 heterotic string theory remains an attractive scenario for phenomenology and cosmology. The particle spectrum is reviewed and the issues of gauge coupling unification, dilaton stabilization and modular cosmology are discussed. A specific model for condensation and supersymmetry breaking, that respects known constraints from string theory and is phenomenologically viable, is described

  13. Some reflections on clinical supervision: an existential-phenomenological paradigm. (United States)

    Jones, A


    This paper reviews psychotherapy, counselling, and nursing literature related to ideas of clinical supervision and attempts to illuminate areas important to effective health related practice and specifically palliative care. Included are explorations of existentialism, phenomenology, existential phenomenology and psychoanalytical concepts. The phenomenological idea of lived experience is outlined and the Heideggerian notion of authenticity is explored in context. The paper also examines dynamic forces such as hope, trust and personal values that might influence clinical supervision design and so inform a framework for practice. An existential-phenomenological method of supervision is offered as one basis for professional practice. The central recommendation of this paper is, however, to identify relevant value and belief systems to direct clinical supervision. Nursing models might appropriately instruct approaches to supervision. The writer considers the phenomenological idea of the lived experiences as a means by which to at once capture the essence of palliative care nursing and guide the supervision towards the existential idea of authenticity.

  14. Aspects of SUSY phenomenology at the LHC

    International Nuclear Information System (INIS)

    Lindert, Jonas M.R.


    In this thesis we investigate different aspects of supersymmetric collider phenomenology with an emphasis on precision predictions for supersymmetric particle production and decay. In the first part, we introduce the theoretical framework: the Standard Model of particle physics, the concept of supersymmetry and the Minimal Supersymmetric Standard Model (MSSM). Next, resulting collider and early-Universe phenomenology is discussed. In the second part, we present precision calculations for combined scalar quark (squark) production and decay in next-to-leading order (NLO) QCD at the Large Hadron Collider (LHC) within the MSSM. First, the motivation and theoretical approach including computational details of such a combined calculation is presented. Second, an analysis of the signature 2j+E T (+X) via squark-squark production and direct decays into the lightest neutralino, which is assumed to be the lightest supersymmetric particle and hence stable, is presented. Resulting differential distributions are compared with leading order (LO) approximations rescaled by a flat K-factor and a possible impact on cut-and-count searches for supersymmetry at the LHC is examined. Third, the signature 2j+2l+E T (+X) from squark-squark production and decay into a lightest and a second lightest neutralino, with a subsequent electroweak decay chain via an on-shell slepton, is investigated. The impact of NLO corrections on resulting invariant mass distributions is highlighted. Such distributions can be important for future determination of supersymmetry parameters. In the third part, we present a calculation of the dominant cross section contributions for hadronic scalar tau (stau) pair-production within the MSSM, taking into account left-right mixing of the stau eigenstates. We find that b-quark annihilation and gluon fusion can enhance the cross sections by more than one order of magnitude with respect to the Drell-Yan predictions. For long-lived staus, we investigate phenomenological

  15. Curriculum as Post-Intentional Phenomenological Text: Working along the Edges and Margins of Phenomenology Using Post-Structuralist Ideas (United States)

    Vagle, Mark D.


    In this article, I experiment along the edges and margins of the phenomenological notion of intentionality using the Deleuzoguattarian concepts of multiplicity and line of flight. Working from Pinar et al.'s anticipation that phenomenology would undergo discursive shifts tending towards the post-structural, I theorize curriculum as…

  16. Nursing researchers' modifications of Ricoeur's hermeneutic phenomenology. (United States)

    Singsuriya, Pagorn


    Paul Ricoeur's hermeneutic phenomenology has proved to be very helpful in guiding nursing researchers' qualitative analysis of interview transcripts. Modifying Ricoeur's philosophy, a number of nursing researchers have developed their own interpretive methods and shared them, along with their experience, with research community. Major contributors who published papers directly presenting their modifications of Ricoeur's theory include Rene Geanellos (2000), Lena Wiklund, Lisbet Lindholm and Unni Å. Lindström (2002), Anders Lindseth and Astrid Norberg (2004) and Pia Sander Dreyer and Birthe D Pedersen (2009). The aim of this article was to delineate differences among these methods. Descriptive presentation of each method side by side makes clear the differences among them. In addition, Ricoeur's hermeneutic theory is portrayed and compared with the modifications. It is believed that differences that are found can stimulate further thoughts on how to apply Ricoeur's theory in qualitative research in nursing. © 2015 John Wiley & Sons Ltd.

  17. Phenomenological approaches of dissipative heavy ion collisions

    International Nuclear Information System (INIS)

    Ngo, C.


    These lectures describe the properties of dissipative heavy ion collisions observed in low bombarding energy heavy ion reactions. These dissipative collisions are of two different types: fusion and deep inelastic reactions. Their main experimental properties are described on selected examples. It is shown how it is possible to give a simple interpretation to the data. A large number of phenomenological models have been developped to understand dissipative heavy ion collisions. The most important are those describing the collision by classical mechanics and friction forces, the diffusion models, and transport theories which merge both preceding approaches. A special emphasis has been done on two phenomena observed in dissipative heavy ion collisions: charge equilibratium for which we can show the existence of quantum fluctuations, and fast fission which appears as an intermediate mechanism between deep inelastic reactions and compound nucleus formation [fr

  18. Palatini actions and quantum gravity phenomenology

    International Nuclear Information System (INIS)

    Olmo, Gonzalo J.


    We show that an invariant an universal length scale can be consistently introduced in a generally covariant theory through the gravitational sector using the Palatini approach. The resulting theory is able to capture different aspects of quantum gravity phenomenology in a single framework. In particular, it is found that in this theory field excitations propagating with different energy-densities perceive different background metrics, which is a fundamental characteristic of the DSR and Rainbow Gravity approaches. We illustrate these properties with a particular gravitational model and explicitly show how the soccer ball problem is avoided in this framework. The isotropic and anisotropic cosmologies of this model also avoid the big bang singularity by means of a big bounce

  19. Phenomenology of 10^32 Dark Sectors

    CERN Document Server

    Dvali, Gia


    We postulate an exact permutation symmetry acting on 10^32 Standard Model copies as the largest possible symmetry extension of the Standard Model. This setup automatically lowers the fundamental gravity cutoff down to TeV, and thus, accounts for the quantum stability of the weak scale. We study the phenomenology of this framework and show that below TeV energies the copies are well hidden, obeying all the existing observational bounds. Nevertheless, we identify a potential low energy window into the hidden world, the oscillation of the neutron into its dark copies. At the same time, proton decay can be suppressed by gauging the diagonal baryon number of the different copies. This framework offers an alternative approach to several particle physics questions. For example, we suggest a novel mechanism for generating naturally small neutrino masses that are suppressed by the number of neutrino species. The mirror copies of the Standard Model naturally house dark matter candidates. The general experimentally obse...

  20. On the geometric phenomenology of static friction (United States)

    Ghosh, Shankar; Merin, A. P.; Nitsure, Nitin


    In this note we introduce a hierarchy of phase spaces for static friction, which give a graphical way to systematically quantify the directional dependence in static friction via subregions of the phase spaces. We experimentally plot these subregions to obtain phenomenological descriptions for static friction in various examples where the macroscopic shape of the object affects the frictional response. The phase spaces have the universal property that for any experiment in which a given object is put on a substrate fashioned from a chosen material with a specified nature of contact, the frictional behaviour can be read off from a uniquely determined classifying map on the control space of the experiment which takes values in the appropriate phase space.

  1. General phenomenology of underground nuclear explosions

    International Nuclear Information System (INIS)

    Derlich, S.; Supiot, F.


    An essentially qualitatively description is given of the phenomena related to underground nuclear explosions (explosion of a single unit, of several units in line, and simultaneous explosions). In the first chapter are described the phenomena which are common to contained explosions and to explosions forming craters (formation and propagation of a shock-wave causing the vaporization, the fusion and the fracturing of the medium). The second chapter describes the phenomena related to contained explosions (formation of a cavity with a chimney). The third chapter is devoted to the phenomenology of test explosions which form a crater; it describes in particular the mechanism of formation and the different types of craters as a function of the depth of the explosion and of the nature of the ground. The aerial phenomena connected with explosions which form a crater: shock wave in the air and focussing at a large distance, and dust clouds, are also dealt with. (authors) [fr

  2. Palatini actions and quantum gravity phenomenology

    Energy Technology Data Exchange (ETDEWEB)

    Olmo, Gonzalo J., E-mail: [Departamento de Física Teórica and IFIC, Centro Mixto Universidad de Valencia - CSIC, Facultad de Física, Universidad de Valencia, Burjassot-46100, Valencia (Spain)


    We show that an invariant an universal length scale can be consistently introduced in a generally covariant theory through the gravitational sector using the Palatini approach. The resulting theory is able to capture different aspects of quantum gravity phenomenology in a single framework. In particular, it is found that in this theory field excitations propagating with different energy-densities perceive different background metrics, which is a fundamental characteristic of the DSR and Rainbow Gravity approaches. We illustrate these properties with a particular gravitational model and explicitly show how the soccer ball problem is avoided in this framework. The isotropic and anisotropic cosmologies of this model also avoid the big bang singularity by means of a big bounce.

  3. Δ(54) flavor phenomenology and strings

    Energy Technology Data Exchange (ETDEWEB)

    Carballo-Pérez, Brenda [Instituto de Física, Universidad Nacional Autónoma de México,Apartado Postal 20-364, Ciudad de México 01000 (Mexico); HEBA Ideas S.A. de C.V.,Calculistas 37, Cd. Mx. 09400 (Mexico); Peinado, Eduardo; Ramos-Sánchez, Saúl [Instituto de Física, Universidad Nacional Autónoma de México,Apartado Postal 20-364, Ciudad de México 01000 (Mexico)


    Δ(54) can serve as a flavor symmetry in particle physics, but remains almost unexplored. We show that in a classification of semi-realistic ℤ{sub 3}×ℤ{sub 3} heterotic string orbifolds, Δ(54) turns out to be the most natural flavor symmetry, providing additional motivation for its study. We revisit its phenomenological potential from a low-energy perspective and subject to the constraints of string models. We find a model with Δ(54) arising from heterotic orbifolds that leads to the Gatto-Sartori-Tonin relation for quarks and charged-leptons. Additionally, in the neutrino sector, it leads to a normal hierarchy for neutrino masses and a correlation between the reactor and the atmospheric mixing angles, the latter taking values in the second octant and being compatible at three sigmas with experimental data.

  4. Lightning phenomenology in the Tampa Bay Area (United States)

    Peckham, D. W.; Uman, M. A.; Wilcox, C. E., Jr.


    A commercial lightning-locating system (LLS) was employed in the study of lightning phenomenology in the Tampa Bay area of Florida. The LLS output included the time, location, number of strokes per flash, and initial peak magnetic field value of first strokes for lightning ground flashes lowering negative charge. Attention is given to the design and the operation of the LLS, and the experimental results. Measured properties of each of 111 storms are given in a number of tables. It was observed that the apparent motion associated with the lightning activity in storm systems was not due to the motion of the individual single-peak and multiple-peak storms but rather to the successive growth of new storms near previously active storms.

  5. Tutorial review of seismic surface waves' phenomenology (United States)

    Levshin, A. L.; Barmin, M. P.; Ritzwoller, M. H.


    In recent years, surface wave seismology has become one of the leading directions in seismological investigations of the Earth's structure and seismic sources. Various applications cover a wide spectrum of goals, dealing with differences in sources of seismic excitation, penetration depths, frequency ranges, and interpretation techniques. Observed seismic data demonstrates the great variability of phenomenology which can produce difficulties in interpretation for beginners. This tutorial review is based on the many years' experience of authors in processing and interpretation of seismic surface wave observations and the lectures of one of the authors (ALL) at Workshops on Seismic Wave Excitation, Propagation and Interpretation held at the Abdus Salam International Center for Theoretical Physics (Trieste, Italy) in 1990-2012. We present some typical examples of wave patterns which could be encountered in different applications and which can serve as a guide to analysis of observed seismograms.

  6. Politics and the Internet: A Phenomenological Critique

    Directory of Open Access Journals (Sweden)

    Gregory Cameron


    Full Text Available “Politics and the Internet” is a critique of the political potential of the internet from the perspective of Husserl’s discussion of intersubjectivity and objectivity in Cartesian Meditations and Origins of Geometry. Unlike other critiques of the internet from a phenomenological perspective, this paper does not consider the limitations of internet communication from the perspective of the body. Here, rather, the prime concern is with the constitution of objectivity and the ways in which the internet limits this constitution. The paper builds towards a consideration of the essential role of objectivity as a condition of possibility for politics and community. Implicit in the argument is a defence of print and broadcast media.

  7. [Phenomenology of multiculturalism and intercultural pluralism]. (United States)

    Hoyos, Guillermo


    Multiculturalism is defined as the combination, within a given territory, of a social unit and a cultural plurality by way of exchanges and communications among actors who use different categories of expression, analysis and interpretation. A multiculturalist project should not promote a society that is split up into closed groups; on the contrary, it should set forth policies based on communication and cooperation processes among the cultural communities. To understand this concept, we will present the ontological basis of this phenomenonin the search for a communicational solution, with our startpoint being a phenomenological description of the way in which multiculturalism manifests to us in life; to later deepen into the meaning of the phenomenon,and finally offer a pluralist solution to the problems and challenges cultural differences bring about.

  8. On the geometric phenomenology of static friction. (United States)

    Ghosh, Shankar; Merin, A P; Nitsure, Nitin


    In this note we introduce a hierarchy of phase spaces for static friction, which give a graphical way to systematically quantify the directional dependence in static friction via subregions of the phase spaces. We experimentally plot these subregions to obtain phenomenological descriptions for static friction in various examples where the macroscopic shape of the object affects the frictional response. The phase spaces have the universal property that for any experiment in which a given object is put on a substrate fashioned from a chosen material with a specified nature of contact, the frictional behaviour can be read off from a uniquely determined classifying map on the control space of the experiment which takes values in the appropriate phase space.

  9. Phenomenological BRDF modeling for engineering applications (United States)

    Jafolla, James C.; Stokes, Jeffrey A.; Sullivan, Robert J.


    The application of analytical light scattering techniques for virtual prototyping the optical performance of paint coatings provides an effective tool for optimizing paint design for specific optical requirements. This paper describes the phenomenological basis for the scattering coatings computer aided design (ScatCad) code. The ScatCad code predicts the bidirectional reflectance distribution function (BRDF) and the hemispherical directional reflectance (HDR) of pigmented paint coatings for the purpose of coating design optimization. The code uses techniques for computing the pigment single scattering phase function, multiple scattering radiative transfer, and rough surface scattering to calculate the BRDF and HDR based on the fundamental optical properties of the pigment(s) and binder, pigment number density and size distribution, and surface roughness of the binder-interface and substrate. This is a significant enhancement to the two- flux, Kubelka-Munk analysis that has traditionally been used in the coatings industry. Example calculations and comparison with measurements are also presented.

  10. The phenomenology in the environmental aesthetic education

    International Nuclear Information System (INIS)

    Noguera de Echeverri, Ana Patricia


    In this paper we present an abstract about our Philosophical Doctor Thesis make on Campinas University (Sao Paulo, Brazil) titled educacion estetico ambiental y fenomenologia: problemas de la educacion estetico ambiental en la modernidad. In this thesis we do a critical thinking about the epistemological model of relation subject -object on modern education, and on the other side, we work in the construction about a aesthetic - environmental education model. We propose here an aesthetization of the education, for conjoint body and world-of-life (lebenswelt) into scenarios and actors of the pedagogical process. Body and world-of-life, are two concepts of Husserl's phenomenology that open the door about the environment' s studies aesthetization and aesthetic' s studies environment, separated on modernity, between the metaphysical subject and physicality objects. Body and world-of-life -symbolic-biotic- are marginal alterities on modernity. This marginality has been a structural lead on the contemporary environmental problems

  11. Hypnosis phenomenology and the neurobiology of consciousness. (United States)

    Rainville, Pierre; Price, Donald D


    Recent developments in the philosophical and neurobiological studies of consciousness provide promising frameworks to investigate the neurobiology of hypnosis. A model of consciousness phenomenology is described to demonstrate that the experiential dimensions characterizing hypnosis (relaxation and mental ease, absorption, orientation and monitoring, and self-agency) reflect basic phenomenal properties of consciousness. Changes in relaxation-mental ease and absorption, produced by standard hypnotic procedures, are further associated with changes in brain activity within structures critically involved in the basic representation of the body-self and the regulation of states of consciousness. The combination of experiential and modern brain imaging methods offers a unique perspective on hypnotic phenomena and provides new observations consistent with the proposition that hypnosis is an altered state of consciousness.

  12. Yukawa Bound States and Their LHC Phenomenology

    Directory of Open Access Journals (Sweden)

    Enkhbat Tsedenbaljir


    Full Text Available We present the current status on the possible bound states of extra generation quarks. These include phenomenology and search strategy at the LHC. If chiral fourth-generation quarks do exist their strong Yukawa couplings, implied by current experimental lower bound on their masses, may lead to formation of bound states. Due to nearly degenerate 4G masses suggested by Precision Electroweak Test one can employ “heavy isospin” symmetry to classify possible spectrum. Among these states, the color-octet isosinglet vector ω 8 is the easiest to be produced at the LHC. The discovery potential and corresponding decay channels are covered in this paper. With possible light Higgs at ~125 GeV two-Higgs doublet version is briefly discussed.

  13. The phenomenology of Dvali Gabadadze Porrati cosmologies (United States)

    Lue, Arthur


    Cosmologists today are confronted with the perplexing reality that the universe is currently accelerating in its expansion. Nevertheless, the nature of the fuel that drives today's cosmic acceleration is an open and tantalizing mystery. There exists the intriguing possibility that the acceleration is not the manifestation of yet another mysterious ingredient in the cosmic gas tank (dark energy), but rather our first real lack of understanding of gravity itself, and even possibly a signal that there might exist dimensions beyond that which we can currently observe. The braneworld model of Dvali, Gabadadze and Porrati (DGP) is a theory where gravity is altered at immense distances by the excruciatingly slow leakage of gravity off our three-dimensional Universe and, as a modified-gravity theory, has pioneered this line of investigation. I review the underlying structure of DGP gravity and those phenomenological developments relevant to cosmologists interested in a pedagogical treatment of this intriguing model.

  14. The aetiology of non-malarial febrile illness in children in the malariaendemic Niger Delta Region of Nigeria

    Directory of Open Access Journals (Sweden)

    Kemebradikumo Pondei


    Full Text Available Objective: Febrile illnesses are common in childhood and differentiating the causes could be challenging in areas of perennial malaria transmission. To determine the proportion of nonmalarial febrile illness in children, the aetiological agents and their antimicrobial sensitivity pattern. Methods: Blood, urine, throat swab and ear swab samples were obtained from 190 febrile children aged 6 months to 11 years. Malaria parasite was detected by microscopic examination of thick and thin Giemsa-stained films. Smears from ear and throat swabs and urine specimen were cultured on appropriate media. Bacterial isolates were identified by Gram staining, morphology and biochemical tests. Antibiotic susceptibility was tested using the Kirby-Bauer disc diffusion method. Results: The prevalence of non-malarial febrile illnesses was 45.26% (95% CI: 38.21- 52.31. Twenty-four patients (12.6% had at least one sample that was bacterial culture positive. Samples from 62 patients (32.6% were negative for both malaria parasite and bacterial culture. Urinary tract infection was responsible for 8.42%, otitis media 7.89% and pharyngitis 5.78% of the fevers. E.coli, S. aureus and S. pneumoniae were the commonest isolates from urine, ear swab and throat swab samples respectively. S. pneumoniae was responsible for all the positive throat cultures. Bacterial isolates exhibited different degrees of susceptibility to the antibiotics tested, but susceptibility of most of the isolates to oxacillin and cloxacillin was generally poor. Conclusions: Bacterial infections are responsible for a significant proportion of non-malarial febrile illnesses, and diagnostic facilities should be strengthened to detect other causes of febrile illness outside malaria.

  15. Digital finger: beyond phenomenological figures of touch

    Directory of Open Access Journals (Sweden)

    Mika Elo


    Full Text Available Mika Elo is a postdoctoral researcher and lecturer in visual culture at Aalto University School of Arts, Design and Architecture (Aalto-ARTS, Helsinki. His research interests include theory of photographic media, philosophical media theory, and artistic research. He is participating in discussions in these areas in the capacity of curator, visual artist and researcher. He has published articles in Finnish, German, and English among others on Benjamin, Nancy, artistic research and photography theory. His doctoral thesis Valokuvan medium [The Medium of Photography] was published in Finnish in 2005 (Tutkijaliitto, Helsinki. In 2009–2011 he worked in the Figures of Touch research project (, and since 2011 he is the director of Media Aesthetics research group at Aalto-ARTS, Department of Media.Author Biography The article reflects on digitality and interface design in terms of the multiple senses of touch. Touching is presented as a “pathic” sense of being exposed, which implies that touching exceeds the tactile and even the phenomenal world. A particular focus is set on Aristotle's and Husserl's ways of thematizing the sense of touch. In this way, two extremes of the phenomenological thinking of touching are articulated: touching as an indistinct and heterogeneous constituent of sensitivity and touching as the guarantor of immediacy of the sense experience. Referring to Derrida's critical notes concerning haptocentrism, the article attempts to problematize the hand and the finger as phenomenological figures of touch and as holds of haptic realism. The article concludes that insofar as digital interface design aims at haptic realism it conceives of the sense of touch in terms of narcissistic feedback and thus tends to conceal the pathic moment of touching.

  16. Phenomenology of induced electroweak symmetry breaking

    International Nuclear Information System (INIS)

    Chang, Spencer; Galloway, Jamison; Luty, Markus A.; Salvioni, Ennio; Tsai, Yuhsin


    We study the phenomenology of models of electroweak symmetry breaking where the Higgs potential is destabilized by a tadpole arising from the coupling to an “auxiliary” Higgs sector. The auxiliary Higgs sector can be either perturbative or strongly coupled, similar to technicolor models. Since electroweak symmetry breaking is driven by a tadpole, the cubic and quartic Higgs couplings can naturally be significantly smaller than their values in the standard model. The theoretical motivation for these models is that they can explain the 125 GeV Higgs mass in supersymmetry without fine-tuning. The auxiliary Higgs sector contains additional Higgs states that cannot decouple from standard model particles, so these models predict a rich phenomenology of Higgs physics beyond the standard model. In this paper we analyze a large number of direct and indirect constraints on these models. We present the current constraints after the 8 TeV run of the LHC, and give projections for the sensitivity of the upcoming 14 TeV run. We find that the strongest constraints come from the direct searches A 0 →Zh, A 0 →tt-bar, with weaker constraints from Higgs coupling fits. For strongly-coupled models, additional constraints come from ρ + →WZ where ρ + is a vector resonance. Our overall conclusion is that a significant parameter space for such models is currently open, allowing values of the Higgs cubic coupling down to 0.4 times the standard model value for weakly coupled models and vanishing cubic coupling for strongly coupled models. The upcoming 14 TeV run of the LHC will stringently test this scenario and we identify several new searches with discovery potential for this class of models.

  17. Prevalence and Risk Factors of Maladaptive Behaviour in Young Children with Autistic Disorder (United States)

    Hartley, S. L.; Sikora, D. M.; McCoy, R.


    Background: Children with Autistic Disorder (AD) evidence more co-occurring maladaptive behaviours than their typically developing peers and peers with intellectual disability because of other aetiologies. The present study investigated the prevalence of Clinically Significant maladaptive behaviours during early childhood and identified at-risk…


    Directory of Open Access Journals (Sweden)

    Radhakrishnan Natarajan


    Full Text Available BACKGROUND Portal Vein Thrombosis (PVT has become an increasingly recognisable disorder during evaluation of cases of abdominal pain with usage of widespread imaging techniques. VT can result due to various clinical conditions like chronic liver disease, infections, malignancies and hypercoagulable states. The aim of the study is to observe the clinical presentation and to do the aetiological workup of cases of PVT in a tertiary care centre. MATERIALS AND METHODS The study is a cross-sectional observational study done on patients having PVT who presented to Institute of Medical Gastroenterology, MMC and RGGGH, during the period of January 2016-July 2017 were taken up for the study. The clinical presentation of the above patients was observed and their aetiological workup were done. RESULTS Totally, 45 cases were taken into study. 27 were males and 18 were females. Clinical presentation- The main symptoms were abdominal distension (18 patients, 51%, abdominal pain (10 patients, 27%, pain associated with diarrhoea and vomiting (5 patients, 14%, pain with nausea and anorexia (3 patients, 8%. Aetiological workup showed chronic liver disease (24 patients, 54%, prothrombotic states (9 patients, 20%, local factors, prothrombotic risks and idiopathic causes (12 patients, 26%. Detection of PVT were done mostly by portal vein Doppler (32 patients, 72% and computed tomography (13 patients, 27%. CONCLUSION Higher incidence of PVT were seen among patients with chronic liver disease. Prothrombotic states like myeloproliferative disorders and coagulation defects were the next common causes detected. PVT presenting as plain abdominal pain, pain associated with nausea, vomiting and diarrhoea were seen in patients as well thereby suggesting that PVT is an important differential diagnosis in patients presenting as abdominal pain with a negative workup for common causes. With the help of widespread and improved imaging techniques, earlier diagnosis of PVT can be


    Directory of Open Access Journals (Sweden)

    M. Amarendra


    Full Text Available BACKGROUND Respiratory distress is a common problem encountered within the first 48-72 hours of life. It is one of the commonest cause of admission to NICU. So, it is very important to know the aetiology and risk factors associated with development of respiratory distress to provide better management. The aim of the study is to study the aetiology of respiratory distress and the risk factors associated with development of respiratory distress in term newborns. MATERIALS AND METHODS Prospective study of 100 term newborns admitted in our NICU with respiratory distress. General information, history and clinical examination findings of mother and newborn were documented. Time of onset of respiratory distress and the severity of the distress were documented. Severity was assessed using Downe’s clinical scoring. X-ray was done at 6 hours in all newborns. Various aetiologies and risk factors associated with respiratory distress were assessed. RESULTS In our study, the most common cause of respiratory distress was transient tachypnoea of newborn seen in 59% cases followed by early onset sepsis 20% cases and meconium aspiration syndrome 17% cases. Majority of newborn had severe distress (42% followed by moderate distress (35% and mild distress (23%. The risk factors associated with development of respiratory distress were low socioeconomic status, more than four per vaginal examinations, meconium-stained liquor, caesarean section, low birth weight and male sex of the baby. CONCLUSION Transient tachypnoea of newborn is the most common cause of respiratory distress in term newborns and the risk factors for development of respiratory distress are low socioeconomic status, more than four per vaginal examinations, meconiumstained liquor, caesarean section, low birth weight and male sex of the baby. Early diagnosis and management of respiratory distress in newborn is needed to decrease the severity of the disease and to reduce the mortality.

  20. Mycotoxic nephropathy in Bulgarian pigs and chickens: complex aetiology and similarity to Balkan endemic nephropathy

    CSIR Research Space (South Africa)

    Stoev, SD


    Full Text Available , 1–17, iFirst Mycotoxic nephropathy in Bulgarian pigs and chickens: complex aetiology and similarity to Balkan Endemic Nephropathy S.D. Stoeva*, M.F. Duttonb, P.B. Njobehb, J.S. Mosonikb and P.A. Steenkampc aDepartment of General and Clinical... of fungi was done using the keys of Klich and Pitt (1988) and Klich (2002) for Aspergillus spp. and Pitt and Hocking (1997) for Penicillium and Nelson et al. (1983) for Fusarium spp. This was done by observing both macroscopic characteristics...

  1. Driveline infections in patients supported with a HeartMate II: Incidence, aetiology and outcome

    DEFF Research Database (Denmark)

    Bomholt, Tobias Peter Zwergius; Moser, Claus; Sander, Kaare


    Abstract Objectives. To investigate the incidence and outcome of driveline infections in patients supported with a continuous flow left ventricular assist device (HeartMate II (HMII)) and to study the microbiological aetiology. Design. Retrospective analysis of 31 patients who received...... an implantation of a HMII. Follow-up was from implantation to either device explantation, death or closure of the study. Clinical signs of infections were divided into superficial, deep or systemic and compared to culture and gram stain, the clinical course and infectious parameters. Results. The incidence...

  2. Mono-Causal and Multi-Causal Theories of Disease: How to Think Virally and Socially about the Aetiology of AIDS. (United States)

    Furman, Katherine


    In this paper, I utilise the tools of analytic philosophy to amalgamate mono-causal and multi-causal theories of disease. My aim is to better integrate viral and socio-economic explanations of AIDS in particular, and to consider how the perceived divide between mono-causal and multi-causal theories played a role in the tragedy of AIDS denialism in South Africa in the early 2000s. Currently, there is conceptual ambiguity surrounding the relationship between mono-causal and multi-causal theories in biomedicine and epidemiology. Mono-causal theories focus on single, typically microbial, sources of illness and are most concerned with infectious diseases. By contrast, multi-causal theories allow for multiple factors to underpin a disease's aetiology, including socio-economic and behavioural factors, and they usually focus on chronic non-communicable diseases. However, if these theories are taken to be strictly distinct, this prevents the inclusion of both microbial and socio-economic factors in a single explanation of any particular disease. This strict distinction became a problem when trying to explain the disproportionate prevalence of AIDS in southern Africa and ultimately contributed to the tragedy of AIDS denialism in South Africa. In tandem with viewing how the perceived divide between multi-causal and mono-causal theories underpinned AIDS denialism, I examine Thabo Mbeki's specific role, while acknowledging that AIDS is being deprioritised on a broader international level. Overall, I will demonstrate that any long-term plan to eliminate AIDS will require viral and socio-economic factors to be considered simultaneously and that such a theoretical approach requires a clearer understanding of the underlying concepts of disease aetiology.

  3. Sarnet lecture notes on nuclear reactor severe accident phenomenology

    International Nuclear Information System (INIS)

    Trambauer, K.; Adroguer, B.; Fichot, F.; Muller, C.; Meyer, L.; Breitung, W.; Magallon, D.; Journeau, C.; Alsmeyer, H.; Housiadas, C.; Clement, B.; Ang, M.L.; Chaumont, B.; Ivanov, I.; Marguet, S.; Van Dorsselaere, J.P.; Fleurot, J.; Giordano, P.; Cranga, M.


    The 'Severe Accident Phenomenology Short Course' is part of the Excellence Spreading activities of the European Severe Accident Research NETwork of Excellence SARNET (project of the EURATOM 6. Framework programme). It was held at Cadarache, 9-13 January 2006. The course was divided in 14 lectures covering all aspects of severe accident phenomena that occur during a scenario. It also included lectures on PSA-2, Safety Assessment and design measures in new LWR plants for severe accident mitigation (SAM). This book presents the lecture notes of the Severe Accident Phenomenology Short Course and condenses the essential knowledge on severe accident phenomenology in 2008. (authors)

  4. The cruel and unusual phenomenology of solitary confinement. (United States)

    Gallagher, Shaun


    What happens when subjects are deprived of intersubjective contact? This paper looks closely at the phenomenology and psychology of one example of that deprivation: solitary confinement. It also puts the phenomenology and psychology of solitary confinement to use in the legal context. Not only is there no consensus on whether solitary confinement is a "cruel and unusual punishment," there is no consensus on the definition of the term "cruel" in the use of that legal phrase. I argue that we can find a moral consensus on the meaning of "cruelty" by looking specifically at the phenomenology and psychology of solitary confinement.

  5. Phenomenology tools on cloud infrastructures using OpenStack

    Energy Technology Data Exchange (ETDEWEB)

    Campos, I.; Fernandez-del-Castillo, E.; Heinemeyer, S.; Lopez-Garcia, A. [Instituto de Fisica de Cantabria (CSIC-UC), Santander (Spain); Pahlen, F. [Instituto de Fisica de Cantabria (CSIC-UC), Santander (Spain); University of Zaragoza, Instituto de Biocomputacion y Fisica de Sistemas Complejos - BIFI, Zaragoza (Spain); Borges, G. [Laboratorio de Instrumentacao e Fisica Experimental de Particulas - LIP, Lisbon (Portugal)


    We present a new environment for computations in particle physics phenomenology employing recent developments in cloud computing. On this environment users can create and manage ''virtual'' machines on which the phenomenology codes/tools can be deployed easily in an automated way. We analyze the performance of this environment based on ''virtual'' machines versus the utilization of physical hardware. In this way we provide a qualitative result for the influence of the host operating system on the performance of a representative set of applications for phenomenology calculations. (orig.)

  6. Pituitary transcription factors in the aetiology of combined pituitary hormone deficiency. (United States)

    Pfäffle, R; Klammt, J


    The somatotropic axis is the central postnatal regulator of longitudinal growth. One of its major components--growth hormone--is produced by the anterior lobe of the pituitary, which also expresses and secretes five additional hormones (prolactin, thyroid stimulating hormone, follicle stimulating hormone, luteinizing hormone, adrenocorticotropic hormone). Proper development of the pituitary assures the regulation of critical processes such as metabolic control, puberty and reproduction, stress response and lactation. Ontogeny of the adenohypophysis is orchestrated by inputs from neighbouring tissues, cellular signalling molecules and transcription factors. Perturbation of expression or function of these factors has been implicated in the aetiology of combined pituitary hormone deficiency (CPHD). Mutations within the genes encoding for the transcription factors LHX3, LHX4, PROP1, and POU1F1 (PIT1) that act at different stages of pituitary development result in unique patterns of hormonal deficiencies reflecting their differential expression during organogenesis. In the case of LHX3 and LHX4 the phenotype may include extra-pituitary manifestations due to the function of these genes/proteins outside the pituitary gland. The remarkable variability in the clinical presentation of affected patients indicates the influence of the genetic background, environmental factors and possibly stochastic events. However, in the majority of CPHD cases the aetiology of this heterogeneous disease remains unexplained, which further suggests the involvement of additional genes. Identification of these factors might also help to close the gaps in our understanding of pituitary development, maintenance and function. Copyright © 2010 Elsevier Ltd. All rights reserved.

  7. Chicken astrovirus as an aetiological agent of runting-stunting syndrome in broiler chickens. (United States)

    Kang, Kyung-Il; Linnemann, Erich; Icard, Alan H; Durairaj, Vijay; Mundt, Egbert; Sellers, Holly S


    Despite descriptions of runting-stunting syndrome (RSS) in broiler chickens dating back over 40 years, the aetiology has not yet been described. A novel chicken astrovirus (CkAstV) was isolated in an LMH liver cell line from the intestines of chickens affected with RSS. Clinical RSS is characterized by retarded growth and cystic crypt lesions in the small intestine. In 1-day-old broiler chickens infected with the CkAstV isolate, virus was only detected in the intestinal epithelial cells during the first few days after infection. Notably, the preferred host cells are the crypt epithelial cells following initial replication in the villous epithelial cells, thus implying viral preference for immature intestinal cells. Nevertheless, the CkAstV isolate did not induce remarkable pathological changes, despite the presence of the virus in situ. Serial chicken-to-chicken passages of the virus induced increased virulence, as displayed by decreased weight gain and the presence of cystic lesions in the small intestine reproducing clinical RSS in chickens. The analysis of the full-length genome sequences from the isolated CkAstV and the CkAstV from the bird-to-bird passages showed >99 % similarity. The data obtained in this study suggest that the CkAstV isolate is capable of inducing RSS following serial bird-to-bird passages in broilers and is as an aetiological agent of the disease.

  8. A Latter-day Saint Approach to Addiction: Aetiology, Consequences and Treatment in a Theological Context

    Directory of Open Access Journals (Sweden)

    James D. Holt


    Full Text Available This article explores the theological underpinning of the nature, aetiology and treatment of addictions within The Church of Jesus Christ of Latter-day Saints. The first section outlines the “plan of salvation” and how this provides the theological framework for the source and solution to addictions. The final section explores addiction against this background in terms of its aetiology, types, consequences and treatment in a Latter-day Saint context. In so doing it builds on the recognition by the Church in recent years that addiction is a problem in the lives of some of its members and that treatment programs coherent with its teachings and beliefs are necessary. The article concludes by suggesting that while addiction may be more openly discussed within a Latter-day Saint context there is a need to keep this dialogue moving forward. This article does not examine Latter-day Saint teaching within the wider context of psychotherapy and other definitions of addiction; rather it explores the place of addiction as understood within the theological and ecclesiological context of Mormonism.

  9. Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.

    Directory of Open Access Journals (Sweden)

    Lesley Jones


    Full Text Available Late Onset Alzheimer's disease (LOAD is the leading cause of dementia. Recent large genome-wide association studies (GWAS identified the first strongly supported LOAD susceptibility genes since the discovery of the involvement of APOE in the early 1990s. We have now exploited these GWAS datasets to uncover key LOAD pathophysiological processes.We applied a recently developed tool for mining GWAS data for biologically meaningful information to a LOAD GWAS dataset. The principal findings were then tested in an independent GWAS dataset.We found a significant overrepresentation of association signals in pathways related to cholesterol metabolism and the immune response in both of the two largest genome-wide association studies for LOAD.Processes related to cholesterol metabolism and the innate immune response have previously been implicated by pathological and epidemiological studies of Alzheimer's disease, but it has been unclear whether those findings reflected primary aetiological events or consequences of the disease process. Our independent evidence from two large studies now demonstrates that these processes are aetiologically relevant, and suggests that they may be suitable targets for novel and existing therapeutic approaches.

  10. South African Muslim Faith Healers perceptions of mental illness: understanding, aetiology and treatment. (United States)

    Ally, Yaseen; Laher, Sumaya


    The important role that religious beliefs may have on perceptions of mental illness cannot be ignored. Many religions including Islam advocate witchcraft and spirit possession--all of which are thought to influence the behaviour of a person so as to resemble that of a mentally ill individual. Thus this research explored Muslim Faith Healers perceptions of mental and spiritual illness in terms of their understanding of the distinctions between the two, the aetiologies and the treatments thereof. Six Muslim Healers in the Johannesburg community were interviewed and thematic content analysis was used to analyse the data. From the results it is clear that the faith healers were aware of the distinction between mental and spiritual illnesses. It was also apparent that Islam has a clear taxonomy that distinguishes illness and the causes thereof. Treatments are then advised accordingly. Thus this paper argues that the predominant Western view of the aetiology and understanding of mental illness needs to acknowledge the various culturally inclined taxonomies of mental illness so as to better understand and aid clients.

  11. Permanent Childhood Hearing Impairment: Aetiological Evaluation of Infants identified through the Irish Newborn Hearing Screening Programme

    LENUS (Irish Health Repository)

    Smith, A


    The Newborn Hearing Screening Programme (NHSP) was established in Cork University Maternity Hospital (CUMH) in April 2011. Between April 2011 and July 2014, 42 infants were identified with a Permanent Childhood Hearing Impairment (PCHI). Following this diagnosis, infants underwent a paediatric assessment according to recognised guidelines with the intention of identifying the underlying aetiology of the PCHI. The aim of this study was to assess the findings of this aetiological workup via retrospective chart review. PCHI data was obtained from the eSP database. This is a web based information system (eSP) used to track each baby through the screening and referral process A retrospective chart review of these patients was performed. Sixteen (38%) infants were diagnosed with a bilateral sensorineural hearing loss. Two infants had congenital CMV infection. A Connexin 26 gene mutation was detected in one infant. Two infants were diagnosed with Waardenburg syndrome, One with Pendred syndrome and one with Pfeiffer syndrome. Five babies underwent cochlear implantation. Through adherence to the recommended protocol a possible cause of PCHI may be determined. This study has identified areas of future improvement for this service in Ireland.

  12. Viral aetiology influenza like illnesses in Santa Cruz, Bolivia (2010-2012). (United States)

    Delangue, Julie; Roca Sanchez, Yelin; Piorkowski, Géraldine; Bessaud, Maël; Baronti, Cécile; Thirion-Perrier, Laurence; Mafayle, Roxana Loayza; Ardaya, Cinthia Avila; Aguilera, Gabriela Añez; Guzman, Jimmy Revollo; Riera, Javier Lora; de Lamballerie, Xavier


    Acute respiratory infections represent a serious public health issue worldwide but virological aetiologies of Influenza Like Illnesses (ILIs) remain largely unknown in developing countries. This study represents the first attempt to characterise viral aetiologies of ILIs in Bolivia. It was performed in Santa Cruz city from January 2010 to September 2012, based on 564 naso-pharyngeal swabs collected in a National Reference Laboratory and real-time PCR techniques, viral cultures and phylogenetic analyses. 50.2% of samples were positive for at least one virus with influenza viruses (Flu A: ~15%; Flu B: ~9%), rhinoviruses (~8%), coronaviruses (~5%) and hRSV (~4%) being the most frequently identified. The pattern of viral infections varied according to age groups. The elucidation rate was the highest (>60%) amongst patients under 10 yo and the lowest (Bolivia in the study period, originating from Central and North America, Europe, Asia and Australia. Our results emphasise the requirement for a reinforced epidemiological and genetic follow-up of influenza and other ILIs in Bolivia to further inform the preparation of vaccines used in the region, guide vaccination campaigns and improve the medical management of patients.

  13. The collider phenomenology of supersymmetric models (United States)

    Muller, David J.

    Scope and method of study. The purpose of this study is to investigate the phenomenology of various supersymmetric models. First, the Minimal Supersymmetric Standard Model (MSSM) is investigated. This model contains an extended Higgs sector that includes a charged boson. The effect that this charged Higgs boson has on the signatures for top quark pair production at the Tevatron is investigated. The rest of the work is devoted to the phenomenology of models with gauge mediated supersymmetry breaking (GMSB). In GMSB models, the lighter stau can be the next to lightest supersymmetric particle. The signals at hadronic colliders for GMSB models with minimal visible sector content are explored for this case. A GMSB model with non-minimal visible sector content is also explored. This is the left-right symmetric GMSB model which contains doubly charged bosons and fermions that could be light enough in mass to be produced at Run II of the Tevatron. Findings and conclusions. The presence of a charged Higgs boson that is lighter than the top quark is found to have a significant impact on the expected signatures for top quark pair production at the Tevatron. This is marked by an overall decrease in high pT electrons and muons in the final states. In addition, for tan beta less than about one, the three-body decay H+→bbW leads to final states that are not present in the Standard Model. For GMSB models with the lighter stau as the next to lightest supersymmetric particle, the signature at the Tevatron typically involves two or three tau-jets plus large missing transverse energy. This tau-jet signature can be even more pronounced in left-right symmetric GMSB models due to the production of light doubly charged fermions that may couple preferentially to the third generation of leptons. The left-right models can be distinguished from GMSB models with minimal visible sector content by the distribution in angle between the highest ET tau-jets when they come from same sign tau

  14. Risk factors, aetiology and outcome of ischaemic stroke in young adults: the Swiss Young Stroke Study (SYSS). (United States)

    Goeggel Simonetti, Barbara; Mono, Marie-Luise; Huynh-Do, Uyen; Michel, Patrik; Odier, Celine; Sztajzel, Roman; Lyrer, Philippe; Engelter, Stefan T; Bonati, Leo; Gensicke, Henrik; Traenka, Christopher; Tettenborn, Barbara; Weder, Bruno; Fischer, Urs; Galimanis, Aekaterini; Jung, Simon; Luedi, Rudolf; De Marchis, Gian Marco; Weck, Anja; Cereda, Carlo W; Baumgartner, Ralf; Bassetti, Claudio L; Mattle, Heinrich P; Nedeltchev, Krassen; Arnold, Marcel


    Ischaemic stroke (IS) in young adults has been increasingly recognized as a serious health condition. Stroke aetiology is different in young adults than in the older population. This study aimed to investigate aetiology and risk factors, and to search for predictors of outcome and recurrence in young IS patients. We conducted a prospective multicentre study of consecutive IS patients aged 16-55 years. Baseline demographic data, risk factors, stroke aetiology including systematic genetic screening for Fabry disease and severity were assessed and related to functional neurological outcome (modified Rankin Scale, mRS), case fatality, employment status, place of residence, and recurrent cerebrovascular events at 3 months. In 624 IS patients (60% men), median age was 46 (IQR 39-51) years and median NIHSS on admission 3 (IQR 1-8). Modifiable vascular risk factors were found in 73%. Stroke aetiology was mostly cardioembolism (32%) and of other defined origin (24%), including cervicocerebral artery dissection (17%). Fabry disease was diagnosed in 2 patients (0.3%). Aetiology remained unknown in 20%. Outcome at 3 months was favourable (mRS 0-1) in 61% and fatal in 2.9%. Stroke severity (p young adults with IS had modifiable vascular risk factors, emphasizing the importance of prevention strategies. Outcome was unfavourable in more than a third of patients and was associated with initial stroke severity and diabetes mellitus. Previous cerebrovascular events predicted recurrent ones.

  15. Impairment of renal sodium excretion in tropical residents - phenomenological analysis (United States)

    Arthur, S. K.; Aryee, P. A.; Amuasi, J.; Hesse, I. F. A.; Affram, R. K.

    There is evidence of impaired renal sodium excretion in salt-sensitive African Blacks. A decreased rate of renal sodium chloride (NaCl) excretion, low plasma renin activity and a tendency to elevated blood pressure are the hallmarks of salt sensitivity. Recent evidence indicates that increased proximal and distal tubular fluid reabsorption in some tropical residents may explain the impaired sodium excretion in these people. In this study of a cohort population, we speculated that subjects selected from that population might be salt-sensitive. We therefore measured the sodium balance in 10 normotensive male subjects over 10 consecutive days, after they had ingested a normal or a high amount of sodium, as NaCl (salt) in their diet. We quantified their renal sodium excretion rate by phenomenological analysis of their sodium balance data. We also measured plasma renin activity for 7 consecutive days in a separate group of 6 male and 4 female subjects in order to assess the state of their renin/angiotensin system. We selected all our subjects from a cohort population of 269 subjects randomly selected from a community known to have a high prevalence of primary hypertension. Our data on two separate groups of subjects from the same cohort population revealed delayed renal sodium excretion with t1/2 of about 5 days, compared to published data for normal individuals with t1/2 of less than 24 h. Also, plasma renin activity levels were low. Hence, our subjects are salt-sensitive. Quantification of their renal impairment is important for various reasons: it heightens one's appreciation of the problem of salt retention in African Blacks who are salt-sensitive and it also underlines the importance of the need for further research into the benefits of dietary salt restriction for reducing cardiovascular mortality in African populations, as has been done in some Western countries.

  16. Patient non-adherence: an interpretative phenomenological analysis. (United States)

    Dalvi, Vidya; Mekoth, Nandakumar


    Purpose While interpretative phenomenological analysis (IPA) has been used in health psychology research, it has so far not been applied to seek deeper insights into the patients' experiences about treatment. The purpose of this paper is to address this gap by using IPA to understand patient non-adherence. Design/methodology/approach In total, 18 patients with chronic conditions seeking healthcare services in Goa and Karnataka, India, were selected by using the snowball sampling method. In-depth interviews were conducted face to face. A semi-structured questionnaire developed by the researchers was used to collect the data. IPA was used to explore the themes to predict patient non-adherence. Findings The study results indicate that economic factors, health system related factors, social factors and psychological factors impact patient non-adherence. Patient non-adherence includes medication non-adherence and lifestyle modification non-adherence. Research limitations/implications Being cross sectional in design, the results may not be as appropriate as the results derived from a longitudinal study given that non-adherence occurs over time. Practical implications Patient non-adherence is a global health issue. Multidisciplinary approach to enhance patient adherence to treatment should form part of public healthcare policy. Social implications Exploring the factors influencing patient non-adherence will help the health-care industry stakeholders to reduce healthcare cost and improve patient's quality of life. Originality/value Although there is extensive quantitative research on the prevalence of non-adherence, qualitative research is limited. This paper addresses this gap by using IPA to understand patient non-adherence and its factors and dimensions.

  17. Nondisclosure in Triadic Supervision: A Phenomenological Study of Counseling Students (United States)

    Lonn, Marlise R.; Juhnke, Gerald


    Triadic supervision is common within counselor training; however, limited research in professional counseling literature exists describing counseling students' experiences of choosing what to disclose within triadic supervision. Using transcendental phenomenological research, the authors investigated supervisees' nondisclosure within triadic…

  18. An interpretative phenomenological analysis of schema modes in a ...

    African Journals Online (AJOL)

    An interpretative phenomenological analysis of schema modes in a single case of anorexia nervosa: Part 2. Coping modes, healthy adult mode, superordinate themes, and implications for research and practice.

  19. How to develop a phenomenological model of disability

    DEFF Research Database (Denmark)

    Martiny, Kristian Møller Moltke


    During recent decades various researchers from health and social sciences have been debating what it means for a person to be disabled. A rather overlooked approach has developed alongside this debate, primarily inspired by the philosophical tradition called phenomenology. This paper develops...... a phenomenological model of disability by arguing for a different methodological and conceptual framework from that used by the existing phenomenological approach. The existing approach is developed from the phenomenology of illness, but the paper illustrates how the case of congenital disabilities, looking...... at the congenital disorder called cerebral palsy (CP), presents a fundamental problem for the approach. In order to understand such congenital cases as CP, the experience of disability is described as being gradually different from, rather than a disruption of, the experience of being abled, and it is argued...


    DEFF Research Database (Denmark)

    Herholdt-Lomholdt, Sine Maria; Hansen, Finn Thorbjørn

    . Second the questions seem to arise from within the profession, being in resonance with some kind of meaningfulness. A wonder-driven approach to innovation and entrepreneurship seems in some way and degree to grasp the meaning of our professions and the deeper meaning of our existence through what we...... to get in a resonance with some kind of meaningfulness. The study has originality because of the phenomenological research-approach to innovation and entrepreneurship and because of the philosophic-hermeneutic and wonder-driven approach to innovation and entrepreneurship teaching.......This paper questions, how we, from a phenomenological point of view, can describe and understand the phenomenology of innovative questions and processes of questioning when based in a wonder-driven approach to innovation and entrepreneurship. In our research we take on a phenomenological...

  1. The promise of ‘sporting bodies’ in phenomenological thinking

    DEFF Research Database (Denmark)

    Ravn, Susanne; Høffding, Simon


    For decades, qualitative researchers have used phenomenological thinking to advance reflections on particular kinds of lifeworlds. As emphasised by Allen-Collinson phenomenology offers a continuing promise of ‘bringing the body back in’ to theories on sport and physical activity. Turning...... phenomenology to empirically investigate the domain of sport and exercise, phenomenologists employ empirical data to substantiate their claims concerning foundational conditions of our being-in-the-world. In this article, we suggest a way to enhance the collaboration between the two fields by pointing out...... and giving examples of the resource of ‘the factual variation.’ Coined by Shaun Gallagher and developed from the Husserlian eidetic variation, the factual variation uses exceptional cases, normally from pathology, to shed new light on foundational phenomenological concepts. Drawing on our research of sports...

  2. The phenomenology of empathy in medicine: an introduction. (United States)

    Svenaeus, Fredrik


    This article is an introduction to a thematic section on the phenomenology of empathy in medicine, attempting to provide an expose of the field. It also provides introductions to the individual articles of the thematic section.



    Binu Upreti; Forhad Akhtar Zaman; Sushrut Varun Satpathy


    BACKGROUND Diabetes mellitus has become a major public health problem, more so in India, which contributes the most to global diabetes prevalence and the rate seems to be escalating. There is complexity of aetiologies and need for early diagnosis and treatment and the call for finding the burden. The aim of the study is to find the prevalence of diabetes and determine the factors associated with it amongst the native Sikkimese population of Tadong, East Sikkim. MATERIALS AND...

  4. Phenomenology of Dirac Neutralino Dark Matter

    Energy Technology Data Exchange (ETDEWEB)

    Buckley, Matthew R.; Hooper, Dan; Kumar, Jason


    In supersymmetric models with an unbroken R-symmetry (rather than only R-parity), the neutralinos are Dirac fermions rather than Majorana. In this article, we discuss the phenomenology of neutralino dark matter in such models, including the calculation of the thermal relic abundance, and constraints and prospects for direct and indirect searches. Due to the large elastic scattering cross sections with nuclei predicted in R-symmetric models, we are forced to consider a neutralino that is predominantly bino, with very little higgsino mixing. We find a large region of parameter space in which bino-like Dirac neutralinos with masses between 10 and 380 GeV can annihilate through slepton exchange to provide a thermal relic abundance in agreement with the observed cosmological density, without relying on coannihilations or resonant annihilations. The signatures for the indirect detection of Dirac neutralinos are very different than predicted in the Majorana case, with annihilations proceeding dominately to $\\tau^+ \\tau^-$, $\\mu^+ \\mu^-$ and $e^+ e^-$ final states, without the standard chirality suppression. And unlike Majorana dark matter candidates, Dirac neutralinos experience spin-independent scattering with nuclei through vector couplings (via $Z$ and squark exchange), leading to potentially large rates at direct detection experiments. These and other characteristics make Dirac neutralinos potentially interesting within the context of recent direct and indirect detection anomalies. We also discuss the case in which the introduction of a small Majorana mass term breaks the $R$-symmetry, splitting the Dirac neutralino into a pair of nearly degenerate Majorana states.

  5. Receiving group clinical supervision: a phenomenological study. (United States)

    Taylor, Claire

    This study examined the process of group supervision as experienced by one team of biofeedback therapists working in the south of England. A phenomenological study was undertaken to examine the team's perceptions of attending group supervision over time. Ten one-to-one in-depth interviews were conducted, six of which were with biofeedback therapists currently receiving supervision, three with nurses who used to receive this supervision and one interview with the supervisor. A four-stage model detailing how supervisees' experiences changed as a consequence of continued group supervision was developed. Study data revealed how this process allowed the biofeedback therapists to examine their clinical interventions and align their approach and perspective alongside other team members. This was a valuable and safe way of learning 'on the job' for the newer members of the team. The opportunity for free-thinking and reflection on practice supported clinical decision-making and therapeutic nursing. The more experienced supervisees demonstrated how their continued attendance of the group supervision sessions not only confirmed their expertise in role, but also facilitated their colleagues' development, which enhanced role satisfaction. The data also indicated some of the essential supervisory features of this process.

  6. Constrained Supersymmetric Flipped SU(5) GUT Phenomenology

    CERN Document Server

    Ellis, John; Olive, Keith A


    We explore the phenomenology of the minimal supersymmetric flipped SU(5) GUT model (CFSU(5)), whose soft supersymmetry-breaking (SSB) mass parameters are constrained to be universal at some input scale, $M_{in}$, above the GUT scale, $M_{GUT}$. We analyze the parameter space of CFSU(5) assuming that the lightest supersymmetric particle (LSP) provides the cosmological cold dark matter, paying careful attention to the matching of parameters at the GUT scale. We first display some specific examples of the evolutions of the SSB parameters that exhibit some generic features. Specifically, we note that the relationship between the masses of the lightest neutralino and the lighter stau is sensitive to $M_{in}$, as is the relationship between the neutralino mass and the masses of the heavier Higgs bosons. For these reasons, prominent features in generic $(m_{1/2}, m_0)$ planes such as coannihilation strips and rapid-annihilation funnels are also sensitive to $M_{in}$, as we illustrate for several cases with tan(beta)...

  7. A general phenomenological model for work function (United States)

    Brodie, I.; Chou, S. H.; Yuan, H.


    A general phenomenological model is presented for obtaining the zero Kelvin work function of any crystal facet of metals and semiconductors, both clean and covered with a monolayer of electropositive atoms. It utilizes the known physical structure of the crystal and the Fermi energy of the two-dimensional electron gas assumed to form on the surface. A key parameter is the number of electrons donated to the surface electron gas per surface lattice site or adsorbed atom, which is taken to be an integer. Initially this is found by trial and later justified by examining the state of the valence electrons of the relevant atoms. In the case of adsorbed monolayers of electropositive atoms a satisfactory justification could not always be found, particularly for cesium, but a trial value always predicted work functions close to the experimental values. The model can also predict the variation of work function with temperature for clean crystal facets. The model is applied to various crystal faces of tungsten, aluminium, silver, and select metal oxides, and most demonstrate good fits compared to available experimental values.

  8. Phenomenology of the next sequential lepton

    International Nuclear Information System (INIS)

    Rizzo, T.G.


    We consider the phenomenology of a sequential, charged lepton in the mass range 6 --13 GeV. We find the semileptonic branching ratio of such a lepton to be approx. 13%; the dominant two-body modes are found to include the decay L → ν/sub L/F* with a branching ratio approx. 6%. In this analysis we assume that the mass of the lepton under consideration is lighter than the t quark such that decays such as L → ν/sub L/t-barq, where q= (d, s, or b) are kinematically forbidden. We also find that decays such as L → ν/sub L/B* (c-barb) can also be as large as approx. 6% depending on the mixing angles; the lifetime of such a lepton is found to be approx. 2.6 x 10 -12 M/sub L/ -5 sec, where M/sub L/ is in GeV

  9. Phenomenology of Compositeness at the LHC

    CERN Document Server

    Salvioni, Ennio; Zwirner, Fabio

    The hierarchy problem of the weak scale calls for extensions of the Standard Model at the TeV, and thus within the reach of the CERN Large Hadron Collider (LHC). One of the best motivated proposals builds on the idea that the Higgs could be a composite pseudo-Nambu-Goldstone boson. In this thesis we discuss several topics in the phenomenology of composite Higgs models, concentrating mainly on LHC physics. In Chapter 1 we introduce the hierarchy problem and the essential features of viable theories of compositeness at the TeV scale. Chapter 2 is dedicated to a review of concrete constructions realizing the composite Higgs idea, focusing mostly on models with partial compositeness. In Chapter 3 we present the effective Lagrangians suited for describing the Higgs boson and the constraints placed by electroweak precision tests on their parameters. Motivated by hints in the experimental results, we also reconsider the possibility of custodial breaking in the couplings of the Higgs to the W and Z. Chapter 4 is devo...

  10. Automated adaptive inference of phenomenological dynamical models (United States)

    Daniels, Bryan

    Understanding the dynamics of biochemical systems can seem impossibly complicated at the microscopic level: detailed properties of every molecular species, including those that have not yet been discovered, could be important for producing macroscopic behavior. The profusion of data in this area has raised the hope that microscopic dynamics might be recovered in an automated search over possible models, yet the combinatorial growth of this space has limited these techniques to systems that contain only a few interacting species. We take a different approach inspired by coarse-grained, phenomenological models in physics. Akin to a Taylor series producing Hooke's Law, forgoing microscopic accuracy allows us to constrain the search over dynamical models to a single dimension. This makes it feasible to infer dynamics with very limited data, including cases in which important dynamical variables are unobserved. We name our method Sir Isaac after its ability to infer the dynamical structure of the law of gravitation given simulated planetary motion data. Applying the method to output from a microscopically complicated but macroscopically simple biological signaling model, it is able to adapt the level of detail to the amount of available data. Finally, using nematode behavioral time series data, the method discovers an effective switch between behavioral attractors after the application of a painful stimulus.

  11. String Phenomenology: Past, Present and Future Perspectives

    Directory of Open Access Journals (Sweden)

    Alon E. Faraggi


    Full Text Available The observation of a scalar resonance at the Large Hadron Collider (LHC, compatible with perturbative electroweak symmetry breaking, reinforces the Standard Model (SM parameterisation of all subatomic data. The logarithmic evolution of the SM gauge and matter parameters suggests that this parameterisation remains viable up to the Planck scale, where gravitational effects are of comparable strength. String theory provides a perturbatively consistent scheme to explore how the parameters of the Standard Model may be determined from a theory of quantum gravity. The free fermionic heterotic string models provide concrete examples of exact string solutions that reproduce the spectrum of the Minimal Supersymmetric Standard Model. Contemporary studies entail the development of methods to classify large classes of models. This led to the discovery of exophobic heterotic-string vacua and the observation of spinor-vector duality, which provides an insight to the global structure of the space of (2,0 heterotic-string vacua. Future directions entail the study of the role of the massive string states in these models and their incorporation in cosmological scenarios. A complementary direction is the formulation of quantum gravity from the principle of manifest phase space duality and the equivalence postulate of quantum mechanics, which suggest that space is compact. The compactness of space, which implies intrinsic regularisation, may be tightly related to the intrinsic finite length scale, implied by string phenomenology.

  12. The Theory and Phenomenology of Love

    Directory of Open Access Journals (Sweden)

    Paolo Borsa


    Full Text Available This second issue of Interfaces: A Journal fo Medieval European Literatures addresses the subject of "The Theory and Phenomenology of Love." It brings together readings of medieval representations and explanations of love as an affection, passion, sentiment, attraction, or tension, with work on the connections between literary discourses of love and the history both of emotions and gender roles. Approaching the subject of the nature of love, and the ways it manifests itself, the authors create links between scientific and poetic discourse and highlight the relationship between the experiences of love, described and treated in literary texts, and the specific historical, cultural, and social environments in which those texts were produced. Not only do the articles reach original results within their fields; taken as a whole, the dossier, ranging as it does from the Late Antiquity to the fifteenth century, and across a Europe situated within a wider Eurasian space, offers deep insights into social history, the history of emotions, and the study of gender and sexuality.

  13. Phenomenological modeling of abradable wear in turbomachines (United States)

    Berthoul, Bérenger; Batailly, Alain; Stainier, Laurent; Legrand, Mathias; Cartraud, Patrice


    Abradable materials are widely used as coatings within compressor and turbine stages of modern aircraft engines in order to reduce operating blade-tip/casing clearances and thus maximize energy efficiency. However, rubbing occurrences between blade tips and coating liners may lead to high blade vibratory levels and endanger their structural integrity through fatigue mechanisms. Accordingly, there is a need for a better comprehension of the physical phenomena at play and for an accurate modeling of the interaction, in order to predict potentially unsafe events. To this end, this work introduces a phenomenological model of the abradable coating removal based on phenomena reported in the literature and accounting for key frictional and wear mechanisms including plasticity at junctions, ploughing, micro-rupture and machining. It is implemented within an in-house software solution dedicated to the prediction of full three-dimensional blade/abradable coating interactions within an aircraft engine low pressure compressor. Two case studies are considered. The first one compares the results of an experimental abradable test rig and its simulation. The second one deals with the simulation of interactions in a complete low-pressure compressor. The consistency of the model with experimental observations is underlined, and the impact of material parameter variations on the interaction and wear behavior of the blade is discussed. It is found that even though wear patterns are remarkably robust, results are significantly influenced by abradable coating material properties.

  14. Conciliating neuroscience and phenomenology via category theory. (United States)

    Ehresmann, Andrée C; Gomez-Ramirez, Jaime


    The paper discusses how neural and mental processes correlate for developing cognitive abilities like memory or spatial representation and allowing the emergence of higher cognitive processes up to embodied cognition, consciousness and creativity. It is done via the presentation of MENS (for Memory Evolutive Neural System), a mathematical methodology, based on category theory, which encompasses the neural and mental systems and analyzes their dynamics in the process of 'becoming'. Using the categorical notion of a colimit, it describes the generation of mental objects through the iterative binding of distributed synchronous assemblies of neurons, and presents a new rationale of spatial representation in the hippocampus (Gómez-Ramirez and Sanz, 2011). An important result is that the degeneracy of the neural code (Edelman, 1989) is the property allowing for the formation of mental objects and cognitive processes of increasing complexity order, with multiple neuronal realizabilities; it is essential "to explain certain empirical phenomena like productivity and systematicity of thought and thinking (Aydede 2010)". Rather than restricting the discourse to linguistics or philosophy of mind, the formal methods used in MENS lead to precise notions of Compositionality, Productivity and Systematicity, which overcome the dichotomic debate of classicism vs. connectionism and their multiple facets. It also allows developing the naturalized phenomenology approach asked for by Varela (1996) which "seeks articulations by mutual constraints between phenomena present in experience and the correlative field of phenomena established by the cognitive sciences", while avoiding their pitfalls. Copyright © 2015. Published by Elsevier Ltd.

  15. Photochemical Phenomenology Model for the New Millenium (United States)

    Bishop, James; Evans, J. Scott


    This project tackles the problem of conversion of validated a priori physics-based modeling capabilities, specifically those relevant to the analysis and interpretation of planetary atmosphere observations, to application-oriented software for use in science and science-support activities. The software package under development, named the Photochemical Phenomenology Modeling Tool (PPMT), has particular focus on the atmospheric remote sensing data to be acquired by the CIRS instrument during the CASSINI Jupiter flyby and orbital tour of the Saturnian system. Overall, the project has followed the development outline given in the original proposal, and the Year 1 design and architecture goals have been met. Specific accomplishments and the difficulties encountered are summarized in this report. Most of the effort has gone into complete definition of the PPMT interfaces within the context of today's IT arena: adoption and adherence to the CORBA Component Model (CCM) has yielded a solid architecture basis, and CORBA-related issues (services, specification options, development plans, etc.) have been largely resolved. Implementation goals have been redirected somewhat so as to be more relevant to the upcoming CASSINI flyby of Jupiter, with focus now being more on data analysis and remote sensing retrieval applications.

  16. Nucleon-nucleon theory and phenomenology

    International Nuclear Information System (INIS)

    Signell, P.


    This project involves five inter-related subprojects: (1) derivation of the intermediate range nucleon-nucleon interaction using a new method that utilizes much shorter and simpler analytic continuation through the unphysical region that lies between the πN and ππ physical regions of the N anti N → ππ amplitude (with significantly improved accuracy for the nucleon-nucleon interaction); (2) construction of a short range phenomenological potential that, with the theoretical part mentioned above, gives a precise fit to the nucleon-nucleon data and is parameterized for easy use in nucleon calculations; (3) phase shift analyses of the world data below 400 MeV, especially the large amount of very precise data below 20 MeV and the new data near 55 MeV that have never been analyzed properly; (4) the introduction of a K-matrix formulation of the Optimal Polynomial Expansion in order to accelerate convergence of the partial wave series at LAMPF energies; and (5) setting up of a cooperatively evaluated permanent nucleon-nucleon data bank in the 0-1200 MeV range that can be used by all nucleon-nucleon reseachers

  17. Phenomenology of Flavon Fields at the LHC

    International Nuclear Information System (INIS)

    Tsumura, Koji; Velasco-Sevilla, Liliana


    We study low energy constraints from flavour violating processes, production and decay at the LHC of a scalar field φ (flavon) associated to the breaking of a non supersymmetric Abelian family symmetry at the TeV scale. This symmetry is constrained to reproduce fermion masses and mixing, up to O(1) coefficients. The non-supersymmetric gauged U(1) models considered are severely restricted by cancellation of anomalies and LEP bounds on contact interactions, consequently its phenomenology is out of the LHC reach. We therefore introduce an effective U(1) which is not gauged and it is broken explicitly by a CP odd term at the TeV scale. This help us to explore flavour violating processes, production and decay at the LHC for these kind of light scalars. In this context we first study the constraints on the flavon mass and its vacuum expectation value from low energy flavour changing processes such as μ→ eγ. We find that a flavon of about m φ φ >∼ m t , and τμ-bar for m t , which could be effectively useful to detect flavons. (author)

  18. Solar Energetic Particle Events: Phenomenology and Prediction (United States)

    Gabriel, S. B.; Patrick, G. J.


    Solar energetic particle events can cause major disruptions to the operation of spacecraft in earth orbit and outside the earth's magnetosphere and have to be considered for EVA and other manned activities. They may also have an effect on radiation doses received by the crew flying in high altitude aircraft over the polar regions. The occurrence of these events has been assumed to be random, but there would appear to be some solar cycle dependency with a higher annual fluence occuring during a 7 year period, 2 years before and 4 years after the year of solar maximum. Little has been done to try to predict these events in real-time with nearly all of the work concentrating on statistical modelling. Currently our understanding of the causes of these events is not good. But what are the prospects for prediction? Can artificial intelligence techniques be used to predict them in the absence of a more complete understanding of the physics involved? The paper examines the phenomenology of the events, briefly reviews the results of neural network prediction techniques and discusses the conjecture that the underlying physical processes might be related to self-organised criticality and turblent MHD flows.

  19. Phenomenology of School Leaders' Experiences of Ethical Dilemmas


    Guy, Timothy Michael


    This research study explores the intersection of school leadership and ethics. This study used the hermeneutic phenomenological approach described by Max Van Manen (1990, 2014) to explore the question: How do school leaders experience ethical dilemmas in their role as school leaders? Hermeneutic phenomenology seeks to find the meaning of a phenomenon, which in this case is the experience of an ethical dilemma. Hermeneutic refers to the interpretive-reflective-analytical component and phenom...

  20. Foregrounding the relational domain - phenomenology, enactivism and care ethics

    Czech Academy of Sciences Publication Activity Database

    Urban, Petr


    Roč. 5, č. 1 (2016), s. 171-182 ISSN 2226-5260 R&D Projects: GA ČR(CZ) GA16-23046S Institutional support: RVO:67985955 Keywords : phenomenology * care ethics * phenomenological ethics * enactivism * the lived body * intersubjectivity * relationality Subject RIV: AA - Philosophy ; Religion