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Sample records for preuss salt detachment

  1. Activity budget of Preuss's red colobus ( Procolobus preussi ) in ...

    African Journals Online (AJOL)

    Preuss's red colobus is critically endangered and endemic to Cameroon and Nigeria. It is one of the least studied red colobus species and therefore further knowledge about the species is crucial for conservation work. Activity budget of Preuss's red colobus was carried in the southern part of Korup National Park, South ...

  2. Synthesis of Salt Soluble Proteins in Barley. Pulse-Labeling Study of Grain Filling in Liquid-Cultured Detached Spikes

    DEFF Research Database (Denmark)

    Giese, Nanna Henriette; Hejgaard, Jørn

    1984-01-01

    The accumulation of salt-soluble proteins in the endosperm of developing barley (Hordeum vulgare L.) grains was examined. Detached spikes of barley were cultured at different levels of nitrogen nutrition and pulse-labeled with [14C] sucrose at specific times after anthesis. Proteins were extracte...

  3. Hanging-wall deformation and gas-migration associated to a major salt detaching fault in the Norwegian Danish Basin

    Science.gov (United States)

    Clausen, O. R.; Andresen, K. J.; Mauritzen, E. K.; Connolly, D.; Korstgård, J. A.

    2015-10-01

    The central and southern regions of the North Sea Basin are characterized by mobile Zechstein Salt and represent an excellent area to study listric normal fault development related to halokinesis. The North Sea Basin-in spite of being a mature explored hydrocarbon producing basin-contains a generally not fully understood hydrocarbon plumbing system. Faults and associated fluid migration routes represent critical elements of the plumbing system. Here we present a combined 3D seismic mapping of a listric fault and detailed seismic attribute analysis of shallow gas anomalies near the fault implying a close and complex relationship between a major detaching fault, hangingwall deformation and fluid migration and entrapment. The fault and associated antithetic and secondary synthetic faults is controlled by the growth of the underlying salt structure. Three separate segments of the fault are recognized showing distinct and varying characteristics of structural maturity and fluid migration. The studied fault and shallow gas anomalies thus represent an example of a complex faulted shallow fluid migration system developing in relation to an underlying salt structure which could be relevant for understanding similar salt, fault and fluid migration systems around the world.

  4. Retinal Detachment Vision Simulator

    Science.gov (United States)

    ... What Is a Torn or Detached Retina? Retinal Detachment: Torn or Detached Retina Causes Retinal Detachment: Who Is At Risk for a Torn or Detached Retina? Retinal Detachment: Torn or Detached Retina Symptoms Retinal Detachment: Torn or Detached Retina Diagnosis ...

  5. Retinal Detachment

    Science.gov (United States)

    ... specific questions. Retinal Detachment Defined What is retinal detachment? The retina is the light-sensitive layer of tissue that ... the most common. Tractional —In this type of detachment, scar tissue on the retina’s surface contracts and causes the retina to separate ...

  6. Retinal Detachment: Torn or Detached Retina Symptoms

    Science.gov (United States)

    ... Health / Eye Health A-Z Detached or Torn Retina Sections Retinal Detachment: What Is a Torn or ... Detachment Vision Simulator Retinal Detachment: Torn or Detached Retina Symptoms Leer en Español: Síntomas de desgarramiento o ...

  7. Divertor detachment

    Science.gov (United States)

    Krasheninnikov, Sergei

    2015-11-01

    The heat exhaust is one of the main conceptual issues of magnetic fusion reactor. In a standard operational regime the large heat flux onto divertor target reaches unacceptable level in any foreseeable reactor design. However, about two decades ago so-called ``detached divertor'' regimes were found. They are characterized by reduced power and plasma flux on divertor targets and look as a promising solution for heat exhaust in future reactors. In particular, it is envisioned that ITER will operate in a partly detached divertor regime. However, even though divertor detachment was studied extensively for two decades, still there are some issues requiring a new look. Among them is the compatibility of detached divertor regime with a good core confinement. For example, ELMy H-mode exhibits a very good core confinement, but large ELMs can ``burn through'' detached divertor and release large amounts of energy on the targets. In addition, detached divertor regimes can be subject to thermal instabilities resulting in the MARFE formation, which, potentially, can cause disruption of the discharge. Finally, often inner and outer divertors detach at different plasma conditions, which can lead to core confinement degradation. Here we discuss basic physics of divertor detachment including different mechanisms of power and momentum loss (ionization, impurity and hydrogen radiation loss, ion-neutral collisions, recombination, and their synergistic effects) and evaluate the roles of different plasma processes in the reduction of the plasma flux; detachment stability; and an impact of ELMs on detachment. We also evaluate an impact of different magnetic and divertor geometries on detachment onset, stability, in- out- asymmetry, and tolerance to the ELMs. Supported by the U.S. Department of Energy Office of Science, Office of Fusion Energy Sciences under Award Number DE-DE-FG02-04ER54739 at UCSD.

  8. Retinal Detachment: Torn or Detached Retina Diagnosis

    Science.gov (United States)

    ... Health / Eye Health A-Z Detached or Torn Retina Sections Retinal Detachment: What Is a Torn or ... Detachment Vision Simulator Retinal Detachment: Torn or Detached Retina Diagnosis Leer en Español: Diagnóstico de un desgarramiento ...

  9. Retinal Detachment

    Directory of Open Access Journals (Sweden)

    Adnan Riaz, MD

    2018-04-01

    Full Text Available History of present illness: A 58-year-old female presented to the emergency department reporting six days of progressive, atraumatic left eye vision loss. Her symptoms started with the appearance of dark spots and “spider webs,” and then progressed to darkening of vision in her left eye. She reports mild pain since yesterday. Her review of symptoms was otherwise negative. Ocular physical examination revealed normal external appearance, intact extraocular movements, and visual acuities of 20/25 OD and light/dark sensitivity OS. Fluorescein uptake was negative and slit lamp exam was unremarkable. Significant findings: Bedside ocular ultrasound revealed a serpentine, hyperechoic membrane that appeared tethered to the optic disc posteriorly with hyperechoic material underneath. These findings are consistent with retinal detachment (RD and associated retinal hemorrhage. Discussion: The retina is a layer of organized neurons that line the posterior portion of the posterior chamber of the eye. RD occurs when this layer separates from the underlying epithelium, resulting in ischemia and progressive photoreceptor degeneration, with potentially rapid and permanent vision loss if left untreated.1 Risk factors include advanced age, male sex (60%, race (Asians and Jews, and myopia and lattice degeneration.2 Bedside ultrasound (US performed by emergency physicians provides a valuable tool that has been used by ophthalmologists for decades to evaluate intraocular disease.1,3 Findings on bedside ultrasound consistent with RD include a hyperechoic membrane floating in the posterior chamber. RD usuallyremain tethered to the optic disc posteriorly and do not cross midline, a feature distinguishing them from posterior vitreous detachments. Associated retinal hemorrhage, seen as hyperechoic material under the retinal flap, can often be seen.1,2 US can also distinguish between “mac-on” and “mac-off” detachments. If the retina is still attached to the

  10. Attempted predation by Nigeria-Cameroon chimpanzees (Pan troglodytes ellioti) on Preuss's red colobus (Procolobus preussi) in the Ebo forest, Cameroon.

    Science.gov (United States)

    Morgan, Bethan J; Suh, John Ngu; Abwe, Ekwoge E

    2012-01-01

    We describe the first observation of a predation attempt by Nigerian-Cameroon chimpanzees (Pan troglodytes ellioti) on Preuss's red colobus (Procolobus preussi) in the Ebo forest, Cameroon. The activity, which was observed for 15 min, primarily involved 1 chimpanzee and 1 red colobus individual, with a further 2 chimpanzees observing the event. Although the behaviour was interrupted when we were detected by the chimpanzees, we believe that this is the first recorded observation of hunting behaviour in Nigeria-Cameroon chimpanzees. Copyright © 2013 S. Karger AG, Basel.

  11. Retinal detachment repair

    Science.gov (United States)

    ... area (the macula). This can help prevent further detachment of the retina. It also will increase the chance of preserving ... buckling; Vitrectomy; Pneumatic retinopexy; Laser retinopexy; Rhegmatogenous retinal detachment repair Images ... detachment repair - series References Connolly BP, Regillo ...

  12. Retinal Detachment: Torn or Detached Retina Treatment

    Science.gov (United States)

    ... in special positions for a time. Do not fly in an airplane or travel at high altitudes until you are ... With an oil bubble, it is safe to fly on an airplane. Most retinal detachment surgeries (80 to 90 percent) ...

  13. Plasma detachment in divertor tokamaks

    Science.gov (United States)

    Leonard, A. W.

    2018-04-01

    Observations of divertor plasma detachment in tokamaks are reviewed. Plasma detachment is characterized in terms of transport and dissipation of power, momentum and particle flux along the open field lines from the midplane to the divertor. Asymmetries in detachment onset and other characteristics between the inboard and outboard divertor plasmas is found to be primarily driven by plasma E× B drifts. The effect of divertor plate geometry and magnetic configuration on divertor detachment is summarized. Control of divertor detachment has progressed with a development of a number of diagnostics to characterize the detached state in real-time. Finally the compatibility of detached divertor operation with high performance core plasmas is examined.

  14. Retinal Detachment in Preeclampsia

    Directory of Open Access Journals (Sweden)

    Prado Renata Silva do

    2002-01-01

    Full Text Available Preeclampsia is an obstetric disease of unknown cause that affects approximately 5% of pregnant women. The visual system may be affected with variable intensity, being the retinal detachment a rare complication. The retinal detachment in preeclampsia is usually bilateral and serous, and its pathogenesis is related to the choroidal ischemia secondary to an intense arteriolar vasospasm. The majority of patients have complete recovery of vision with clinical management, and surgery is unnecessary. This is a case report of a 27 year old patient who developed the severe form of preeclampsia on her first pregnancy. She had progressive blurred vision, until she could see only shadows. Ophthalmic examination diagnosed spread and bilateral retinal detachment. With blood pressure control at postpartum, the patient had her retina reattached, and recovery of vision.

  15. Safety detaching hook specification.

    CSIR Research Space (South Africa)

    Roux, JD

    1999-05-01

    Full Text Available Single-sided Impact Tests 14 Appendix C Record of Amendments 15 5. REFERENCES 17 4 1. INTRODUCTION 1.1 Subiect The subject of this specification is safety detaching hooks for mine shaft conveyances. According to South African Law1 it is a legal... after a full detachment in the catch plate or bell. Engineer The Mine Engineer, or his authorised sub-ordinate, legally appointed in terms of an Act to be responsible for shaft equipment. NDE Non-Destructive Examination. OEM Original Equipment...

  16. Detachable caster adapter

    Science.gov (United States)

    Mohr, R. J.

    1969-01-01

    Detachable caster adapter moves heavy welding tables when fork lift trucks are not practical. A support saddle on the adapter, connected to the caster platform by means of a hinge, fits the leg of the welding table, but can be modified to fit other leg configurations.

  17. Pneumatic retinopexy for retinal detachment associated with severe choroidal detachment.

    Science.gov (United States)

    Yeung, Ling; Kokame, Gregg T; Brod, Roy D; Lightman, David A; Lai, James C

    2011-01-01

    The purpose of this study was to evaluate the role of pneumatic retinopexy as an initial management of retinal detachment associated with hypotony, severe choroidal detachment, and vitritis. Retrospective, interventional, noncomparative case series. We included nine eyes from nine patients (six women and three men) with retinal detachment associated with hypotony, severe choroidal detachment, and vitritis managed with pneumatic retinopexy (either SF6 or C3F8) as their initial management between January 1, 1992, and December 31, 2007. Hypotony and choroidal detachment were rapidly and significantly improved 1 to 3 days after pneumatic retinopexy in all patients. The extent of retinal detachment was decreased in five patients. After vitreoretinal surgery for these five patients, all had attached retina. Complete reattachment of the retina was noted in four patients after pneumatic retinopexy. Two of these patients did not require further surgery because the entire retina remained attached at 6 months and 16 months postoperatively. Pneumatic retinopexy is a useful initial procedure in managing retinal detachment associated with hypotony, severe choroidal detachment, and vitritis. By rapidly resolving the hypotony and choroidal detachments, it facilitates subsequent surgical repair of this complicated retinal detachment. In addition, complete retinal reattachment after pneumatic retinopexy alone was initially achieved in 33% of eyes.

  18. Between Involvement and Detachment

    DEFF Research Database (Denmark)

    Thomasen, Gry

    stood between the current ‘balanced’ Western Europe and the Europe of the pre-War period. In addition the administration held the opinion that the German problem and the Western European détente tampered with the US unilateralism in its relations with the Soviet Union, and its position as the leader....... Thus the US proposed the Harmel formula before Harmel. In general, the developments in Western Europe put the Johnson administration in a state of alarm, and the European allies therefore had a larger impact on America’s policies, except in the essentially detached nuclear policy, which...

  19. Paediatric retinal detachment: a review

    Directory of Open Access Journals (Sweden)

    Raffaele Nuzzi

    2017-10-01

    Full Text Available Paediatric retinal detachment (PRD is an uncommon and challenging disease; it differs from adult detachments in etiology, anatomical characteristics, management and prognosis. PRDs can be particularly challenging, even for the most expert paediatric surgeons due to the higher prevalence of total retinal detachments, late diagnosis and bilateral involvement with respect to those which occur in adulthood. Moreover, the anatomical success, when achieved, is frequently not related to a functional recover. Postsurgical adverse events, refractive errors and amblyopia may additionally undermine the final outcome. Up to date there are few reviews regarding the approach of retinal detachment in children, mainly dealing with rhegmatogenous retinal detachment. In this review, rhegmatogenous, retinopathy of prematurity-related and Coats’-related PRDs were considered. The available literature from the last decades were reviewed and summarized. Epidemiology, etiology and clinical presentation, together with therapeutic approaches and outcomes have been reviewed and discussed.

  20. [Prophylactic treatment of retinal detachment].

    Science.gov (United States)

    Binder, S; Riss, B

    1981-08-01

    The indications for and results of prophylactic treatment of retinal detachment during a period of five years are reported and compared with the results in the literature. Half of the cases (3 out of 6 eyes) which developed a retinal detachment had been horse-shoe tears combined with a vitreous hemorrhage. For this reason a small buckle operation is recommended in these cases, to prevent further traction. Lattice degeneration should rather be observed than treated, except in special cases: This includes eyes where the fellow eye had a detachment from a lattice degeneration, cases in which one eye is blind from an uncured detachment or has no useful visual acuity, and eyes whose fellow eye has giant tears. In aphakic eyes treatment of lattice degeneration is recommended, because the incidence of detachment from these areas is high, especially in young aphakic cases. In one aphakic eye which had been photocoagulated several times the formation of a preretinal membrane was observed.

  1. Drusenoid retinal pigment epithelium detachments

    Directory of Open Access Journals (Sweden)

    Miguel Hage Amaro

    2015-10-01

    Full Text Available ABSTRACT The authors make a review of drusenoid retinal pigment epithelium detachments(DPDs, a form of retinal pigment epithelium detachment(PED that evolves from confluent and large soft drusen.Drusenoidretinal pigment epithelial detachments are a recognized element of the "dry" AMD. Until now, no treatment is indicated in drusenoid PEDs. The authors describe the clinical characteristics of drusenoid retinal pigment epithelium detachments (DPEDs and make a review of the DPEDs related in the international literature. We related in this revision paper the multimodal advanced image exams in two cases of dusenoid retinal pigment epithelium detachments (DPEDs and the general characteristics of thisfinding associated with Dry Macular degeneration.Upon examination of the ocular fundusDPEDs emerge as well-circumscribed yellow or yellow–white elevations of the RPE that are usually found within the macula.They may show scalloped borders and a slightly irregular surface. When visualized using fluorescein angiography (FA,DPEDs are typically described as faint hyper-fluorescent in the early phase followed by a slow increase in fluorescence throughout the transit stage of the study without late leakage. With optical coherence tomography (OCT, drusenoid PEDs usually show a smooth contour of the detached hyperreflective RPE band that may have an undulating appearance.Drusenoid PEDs encompass far above the ground possibility type of "dry" AMD that develops in relationship with large confluent soft drusen.At this point no treatment is utilized in drusenoid retinal pigment epithelium detachment(DPEDs.

  2. Shock detachment from curved wedges

    Science.gov (United States)

    Mölder, S.

    2017-09-01

    Curved shock theory is used to show that the flow behind attached shocks on doubly curved wedges can have either positive or negative post-shock pressure gradients depending on the freestream Mach number, the wedge angle and the two wedge curvatures. Given enough wedge length, the flow near the leading edge can choke to force the shock to detach from the wedge. This local choking can preempt both the maximum deflection and the sonic criteria for shock detachment. Analytical predictions for detachment by local choking are supported by CFD results.

  3. Controlling marginally detached divertor plasmas

    Science.gov (United States)

    Eldon, D.; Kolemen, E.; Barton, J. L.; Briesemeister, A. R.; Humphreys, D. A.; Leonard, A. W.; Maingi, R.; Makowski, M. A.; McLean, A. G.; Moser, A. L.; Stangeby, P. C.

    2017-06-01

    A new control system at DIII-D has stabilized the inter-ELM detached divertor plasma state for H-mode in close proximity to the threshold for reattachment, thus demonstrating the ability to maintain detachment with minimal gas puffing. When the same control system was instead ordered to hold the plasma at the threshold (here defined as T e  =  5 eV near the divertor target plate), the resulting T e profiles separated into two groups with one group consistent with marginal detachment, and the other with marginal attachment. The plasma dithers between the attached and detached states when the control system attempts to hold at the threshold. The control system is upgraded from the one described in Kolemen et al (2015 J. Nucl. Mater. 463 1186) and it handles ELMing plasmas by using real time D α measurements to remove during-ELM slices from real time T e measurements derived from divertor Thomson scattering. The difference between measured and requested inter-ELM T e is passed to a PID (proportional-integral-derivative) controller to determine gas puff commands. While some degree of detachment is essential for the health of ITER’s divertor, more deeply detached plasmas have greater radiative losses and, at the extreme, confinement degradation, making it desirable to limit detachment to the minimum level needed to protect the target plate (Kolemen et al 2015 J. Nucl. Mater. 463 1186). However, the observed bifurcation in plasma conditions at the outer strike point with the ion B   ×  \

  4. Retinal Detachment Associated With Atopic Dermatitis.

    Science.gov (United States)

    Kothari, Nikisha; Young, Ryan C; Read, Sarah P; Tutiven, Jacqueline; Perez, Victor L; Flynn, Harry W; Berrocal, Audina M

    2017-06-01

    Ocular manifestations related to atopic dermatitis include keratoconus, keratoconjunctivitis, cataract, and retinal detachment. The authors report three cases of retinal detachment associated with atopic dermatitis. Although the pathogenesis is poorly understood, chronic blunt trauma may play a role in the development of retinal detachment. In addition, retinal detachments associated with atopic dermatitis may have lower rates of successful retinal detachment repair. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:513-517.]. Copyright 2017, SLACK Incorporated.

  5. Ancient Wall Tiles – The Importance of the Glaze/Ceramic Interface in Glaze Detachment

    Directory of Open Access Journals (Sweden)

    Marisa COSTA

    2014-04-01

    Full Text Available One of the most severe pathologies suffered by early industrially produced tiles in Portugal in late nineteenth century is glaze detachment in wall tiles placed in the lower part of the façade. It is known that salts crystallize provoking the glaze detachment, destroying the waterproofing and the beauty of the wall tile and this is one of the crucial factors towards this occurrence. The present work questions the importance of the thickness of glaze/ceramic body interface, in what concerns glaze detachment provoked by salt crystallization. SEM-EDS was used to perform all the observations that lead to the conclusion that the exuberance of the interface between glaze and ceramic body has no influence in the resistance of the glaze to salt crystallization though time, being the porous network more determinant. DOI: http://dx.doi.org/10.5755/j01.ms.20.1.3815

  6. Fasudil, a Clinically Used ROCK Inhibitor, Stabilizes Rod Photoreceptor Synapses after Retinal Detachment.

    Science.gov (United States)

    Townes-Anderson, Ellen; Wang, Jianfeng; Halász, Éva; Sugino, Ilene; Pitler, Amy; Whitehead, Ian; Zarbin, Marco

    2017-06-01

    Retinal detachment disrupts the rod-bipolar synapse in the outer plexiform layer by retraction of rod axons. We showed that breakage is due to RhoA activation whereas inhibition of Rho kinase (ROCK), using Y27632, reduces synaptic damage. We test whether the ROCK inhibitor fasudil, used for other clinical applications, can prevent synaptic injury after detachment. Detachments were made in pigs by subretinal injection of balanced salt solution (BSS) or fasudil (1, 10 mM). In some animals, fasudil was injected intravitreally after BSS-induced detachment. After 2 to 4 hours, retinae were fixed for immunocytochemistry and confocal microscopy. Axon retraction was quantified by imaging synaptic vesicle label in the outer nuclear layer. Apoptosis was analyzed using propidium iodide staining. For biochemical analysis by Western blotting, retinal explants, detached from retinal pigmented epithelium, were cultured for 2 hours. Subretinal injection of fasudil (10 mM) reduced retraction of rod spherules by 51.3% compared to control detachments ( n = 3 pigs, P = 0.002). Intravitreal injection of 10 mM fasudil, a more clinically feasible route of administration, also reduced retraction (28.7%, n = 5, P ROCK, was decreased with 30 μM fasudil ( n = 8-10 explants, P ROCK signaling with fasudil reduced photoreceptor degeneration and preserved the rod-bipolar synapse after retinal detachment. These results support the possibility, previously tested with Y27632, that ROCK inhibition may attenuate synaptic damage in iatrogenic detachments.

  7. The mechanics of retinal detachment

    Science.gov (United States)

    Chou, Tom; Siegel, Michael

    2013-03-01

    We present a model of the mechanical and fluid forces associated with exudative retinal detachments where the retinal photoreceptor cells separate typically from the underlying retinal pigment epithelium (RPE). By computing the total fluid volume flow arising from transretinal, vascular, and retinal pigment epithelium (RPE) pump currents, we determine the conditions under which the subretinal fluid pressure exceeds the maximum yield stress holding the retina and RPE together, giving rise to an irreversible, extended retinal delamination. We also investigate localized, blister-like retinal detachments by balancing mechanical tension in the retina with both the retina-RPE adhesion energy and the hydraulic pressure jump across the retina. For detachments induced by traction forces, we find a critical radius beyond which the blister is unstable to growth. Growth of a detached blister can also be driven by inflamed tissue within which e.g., the hydraulic conductivities of the retina or choroid increase, the RPE pumps fail, or the adhesion properties change. We determine the parameter regimes in which the blister either becomes unstable to growth, remains stable and finite-sized, or shrinks, allowing possible healing. This work supported by the Army Research Office through grant 58386MA

  8. Retinal detachment in paediatric patients

    International Nuclear Information System (INIS)

    Zafar, S. N.; Qureshi, N.; Azad, N.; Khan, A.

    2013-01-01

    Objective: To assess the causes of retinal detachment in children and the various operative procedures requiring vitreoretinal surgical intervention for the same. Study Design: Case series. Place and Duration of Study: Department of Ophthalmology, Al-Shifa Trust Eye Hospital, Rawalpindi, from January 2006 to May 2009. Methodology: A total of 281 eyes of 258 patients, (aged 0 - 18 years) who underwent vitreo-retinal surgical intervention for retinal detachment were included. Surgical log was searched for the type of retinal detachment and its causes. Frequencies of various interventions done in these patients viz. vitrectomy, scleral buckle, use of tamponading agents, laser photocoagulation and cryotherapy were noted. Results were described as descriptive statistics. Results: Myopia was the cause in 62 (22.1%) and trauma in 51 (18.1%) of the eyes. Total retinal detachment (RD) was treated in 94 (33.5%) eyes, sub total RD in 36 (12.8%), recurrent RD in 32 (11.4%), giant retinal tear in 28 (10%), tractional RD in 15 (5.3%) and exudative RD in 2 (0.7%). Prophylactic laser or cryotherapy was applied in 74 (26.3%) of the eyes. Pars plana vitrectomy (PPV) was carried out in 159 (56.6%) eyes while scleral buckle procedure was done in 129 (45.9%) eyes. Silicon oil was used in 149 (53%), perfluorocarbon liquid in 32 (11.4%) and gas tamponade in 20 (7.1%) eyes. Conclusion: The most common cause of retinal detachment in paediatric patients was myopia, followed by trauma. Total RD was more common as compared to the other types. The most common procedure adopted was pars plana vitrectomy followed by scleral buckle procedure. (author)

  9. Kinematic Fitting of Detached Vertices

    Energy Technology Data Exchange (ETDEWEB)

    Mattione, Paul [Rice Univ., Houston, TX (United States)

    2007-05-01

    The eg3 experiment at the Jefferson Lab CLAS detector aims to determine the existence of the $\\Xi_{5}$ pentaquarks and investigate the excited $\\Xi$ states. Specifically, the exotic $\\Xi_{5}^{--}$ pentaquark will be sought by first reconstructing the $\\Xi^{-}$ particle through its weak decays, $\\Xi^{-}\\to\\pi^{-}\\Lambda$ and $\\Lambda\\to\\pi^{-}$. A kinematic fitting routine was developed to reconstruct the detached vertices of these decays, where confidence level cuts on the fits are used to remove background events. Prior to fitting these decays, the exclusive reaction $\\gamma D\\rightarrow pp\\pi^{-}$ was studied in order to correct the track measurements and covariance matrices of the charged particles. The $\\Lambda\\rightarrow p\\pi^{-}$ and $\\Xi^{-}\\to\\pi^{-}\\Lambda$ decays were then investigated to demonstrate that the kinematic fitting routine reconstructs the decaying particles and their detached vertices correctly.

  10. Negative ion detachment cross sections

    International Nuclear Information System (INIS)

    Champion, R.L.; Doverspike, L.D.

    1992-10-01

    The authors have measured absolute cross sections for electron detachment and charge exchange for collision of O and S with atomic hydrogen, have investigated the sputtering and photodesorption of negative ions from gas covered surfaces, and have begun an investigation of photon-induced field emission of electrons from exotic structures. Brief descriptions of these activities as well as future plans for these projects are given below

  11. Variations of posterior vitreous detachment

    OpenAIRE

    Kakehashi, A.; Kado, M.; Akiba, J.; Hirokawa, H.

    1997-01-01

    AIMS—To identify variations in posterior vitreous detachment (PVD) and establish a clinical classification system for PVD.
METHODS—400 consecutive eyes were examined using biomicroscopy and vitreous photography and classified the PVD variations—complete PVD with collapse, complete PVD without collapse, partial PVD with thickened posterior vitreous cortex (TPVC), or partial PVD without TPVC.
RESULTS—In each PVD type, the most frequently seen ocular pathologies were as follows: in complete PVD ...

  12. Classification of posterior vitreous detachment

    OpenAIRE

    Kakehashi, Akihiro; Takezawa, Mikiko; Akiba, Jun

    2013-01-01

    Akihiro Kakehashi,1 Mikiko Takezawa,1 Jun Akiba21Department of Ophthalmology, Jichi Medical University, Saitama Medical Center, Saitama, 2Kanjodori Eye Clinic, Asahikawa, JapanAbstract: Diagnosing a posterior vitreous detachment (PVD) is important for predicting the prognosis and determining the indication for vitreoretinal surgery in many vitreoretinal diseases. This article presents both classifications of a PVD by slit-lamp biomicroscopy and of a shallow PVD by optical coherence tomography...

  13. Posterior vitreous detachment and retinal detachment after cataract surgery.

    Science.gov (United States)

    Ripandelli, Guido; Coppé, Andrea Maria; Parisi, Vincenzo; Olzi, Diego; Scassa, Cecilia; Chiaravalloti, Adele; Stirpe, Mario

    2007-04-01

    To evaluate possible changes of vitreous status in emmetropic eyes after uneventful phacoemulsification surgery, and possible related complications such as the onset of retinal detachment (RD). Retrospective case series. Four hundred fifty-three emmetropic eyes from 453 patients (mean age, 62.03+/-5.57 years) subjected to uneventful phacoemulsification with intraocular lens implantation in the capsular bag were considered in the study. They had a refractive error within +/-0.5 diopters (mean, -0.21+/-0.08). Eyes with peripheral retinal lattice degeneration were included only if asymptomatic and only if the degeneration involved one retinal quadrant. After cataract surgery, the 453 eyes were evaluated preoperatively at days 1, 15, and 30 and months 3, 6, 12, 18, 24, 36, 48, and 60. The whole period of follow-up was 5 years. Evaluation of vitreous status by biomicroscopic examination, indirect binocular ophthalmoscopy, and B-scan ultrasonography. Postoperative onset of posterior vitreous detachment (PVD) and RD. After cataract surgery, a PVD occurred in 107 of 141 (75.88%) eyes without preoperative PVD or lattice degeneration. Posterior vitreous detachment occurred in 41 of 47 eyes (87.23%) with preoperative lattice degeneration and no PVD. Eyes with preoperative lattice degeneration and postoperative PVD showed a higher incidence of RD after cataract surgery (21.27%) than eyes without preoperative PVD or lattice degeneration (0.70%). In all patients with lattice degeneration, RD originated from horseshoe retinal tears on lattice areas located on the superior quadrants. No correlation was observed between the development of RD and age. Our results suggest that the onset of postoperative PVD should be considered an important risk factor for the development of RD after cataract surgery, particularly in eyes with lattice areas.

  14. Classification of posterior vitreous detachment

    Science.gov (United States)

    Kakehashi, Akihiro; Takezawa, Mikiko; Akiba, Jun

    2014-01-01

    Diagnosing a posterior vitreous detachment (PVD) is important for predicting the prognosis and determining the indication for vitreoretinal surgery in many vitreoretinal diseases. This article presents both classifications of a PVD by slit-lamp biomicroscopy and of a shallow PVD by optical coherence tomography (OCT). By biomicroscopy, the vitreous condition is determined based on the presence or absence of a PVD. The PVD then is classified as either a complete posterior vitreous detachment (C-PVD) or a partial posterior vitreous detachment (P-PVD). A C-PVD is further divided into a C-PVD with collapse and a C-PVD without collapse, while a P-PVD is divided into a P-PVD with shrinkage of the posterior hyaloid membrane (P-PVD with shrinkage) and a P-PVD without shrinkage of the posterior hyaloid membrane (P-PVD without shrinkage). A P-PVD without shrinkage has a subtype characterized by vitreous gel attachment through the premacular hole in a posterior hyaloid membrane to the macula (P-PVD without shrinkage [M]). By OCT, a shallow PVD is classified as the absence of a shallow PVD or as a shallow PVD. A shallow PVD is then subclassified as a shallow PVD without shrinkage of the posterior vitreous cortex, a shallow PVD with shrinkage of the posterior vitreous cortex, and a peripheral shallow PVD. A shallow PVD without shrinkage of the posterior vitreous cortex has two subtypes: an age-related shallow PVD and a perifoveal PVD associated with a macular hole. PMID:24376338

  15. Fluorine negative ion detachment kinetics

    Science.gov (United States)

    Burke, R. R.; Miller, W. J.; Gould, R. K.

    1971-01-01

    A study of the rate of F(-) detachment by O and H atoms via the reactions F(-) + O yields FO + e and F(-) + H yields FH+ e was undertaken using a drift tube to produce F(-) ions at various drift velocities and therefore different ion temperatures. Preliminary mobility measurements of F(-) ions in Ar were made, indicating that ion temperatures in the 300 K to 5000 K range could be achieved; however due to numerous difficulties experienced in obtaining a reliable F(-) ion source, the study could not be completed.

  16. Outcomes in bullous retinal detachment

    Directory of Open Access Journals (Sweden)

    Sarah P. Read

    2017-06-01

    Conclusions and importance: GRTs are an uncommon cause of retinal detachment. While pars plana vitrectomy with tamponade is standard in GRT management, there is variability in the use of scleral buckling and PFO in these cases. This is in contrast to retinal dialysis where scleral buckle alone can yield favorable results. Though a baseball ocular trauma is common, retinal involvement is rare compared to other sports injuries such as those occurring with tennis, soccer and golf. Sports trauma remains an important cause of retinal injury and patients should be counseled on the need for eye protection.

  17. Risk factor profile in retinal detachment

    Directory of Open Access Journals (Sweden)

    Azad Raj

    1988-01-01

    Full Text Available 150 cases of retinal detachment comprising 50 patients each of bilateral retinal detachment, unilateral retinal detachment without any retinal lesions in the fellow eve and unilateral retinal detachment with retinal lesions in the fellow eye were studied and the various associated risk factors were statistically analysed. The findings are discussed in relation to their aetiological and prognostic significance in the different types of retinal detachment. Based on these observations certain guidelines are offered which may be of value in decision making, in prophylactic detachment surgery. Tractional breaks in the superior temporal quadrant especially when symptomatic. mandate prophylactic treatment. Urgency is enhanced it′ the patient is aphakic. Associated myopia adds to the urgency. The higher incidence of initial right e′ e involvement in all groups suggests a vascular original possibly ischaemic.

  18. Rhematogenous retinal detachment complicated by severe intraocular inflammation, hypotony, and choroidal detachment.

    OpenAIRE

    Jarrett, W H

    1981-01-01

    An unusual type of rhegmatogenous retinal detachment is described and compared with a control group of patients with detached retina. Features of the condition, in addition to retinal detachment, include severe anterior and posterior uveitis, choroidal detachment, hypotony, deepened anterior chamber, posterior synechiae, iridophakodonesis, and a poor surgical and visual prognosis due to massive periretinal proliferation. The disease occurs in a disproportionately high ratio in blacks. These c...

  19. Detached divertor plasmas in JET

    Energy Technology Data Exchange (ETDEWEB)

    Horton, L.D.; Borrass, K.; Corrigan, G.; Gottardi, N.; Lingertat, J.; Loarte, A.; Simonini, R.; Stamp, M.F.; Taroni, A. [Commission of the European Communities, Abingdon (United Kingdom). JET Joint Undertaking; Stangeby, P.C. [Toronto Univ., ON (Canada). Inst. for Aerospace Studies

    1994-07-01

    In simulations with high radiated power fractions, it is possible to produce the drop in ion current to the divertor targets typical of detached plasmas. Despite the fact that these experiments are performed on beryllium target tiles, radiation from deuterium and beryllium cannot account for the measured power losses. The neutral deuterium levels in the SOL in these plasmas are higher than the model predicts. This may be due to leakage from the divertor or to additional wall sources related to the non-steady nature of these plasmas. In contrast, a surprisingly high level of carbon is present in these discharges; higher even than would be predicted are the divertor target tiles pure carbon. This level may well be large enough to produce the measured radiation. (authors). 6 refs., 2 figs., 1 tab.

  20. Rhegmatogenous retinal detachment and uveitis.

    Science.gov (United States)

    Kerkhoff, Frank T; Lamberts, Querin J; van den Biesen, Pieter R; Rothova, Aniki

    2003-02-01

    To evaluate the frequency, high-risk factors, and visual prognosis of rhegmatogenous retinal detachment (RRD) in patients with uveitis. Retrospective case-control study. We included 1387 consecutive patients with uveitis who consulted our uveitis clinic from January 1990 through December 1997 of whom 43 patients (46 eyes) with RRD were identified. The retinal detachment (RD) controls were 212 consecutive patients with RRD (221 eyes, first occurrence of RD, not associated with uveitis) who were admitted for surgery in the period from April 1999 to April 2000. The uveitis control group consisted of 150 age-matched patients (210 eyes) selected from the entire uveitis series. Retrospective analysis of clinical data. The presence of RRD and eventual risk factors for RRD, such as myopia, retinal lattice degeneration, prior intraocular surgery, anatomic location of uveitis, its specific diagnosis, and clinical manifestations. Furthermore, the surgical and nonsurgical outcomes of RRD, as well as the results of various treatment regimens, were analyzed. RRD was identified in 3.1% of the patients with uveitis. RRD was most frequently associated with panuveitis (6.6%). RRD was associated more frequently with infectious (7.6%) than noninfectious uveitis (2.1%). At the onset of RRD, uveitis was active in most (46%) affected eyes. Proliferative vitreoretinopathy was present in 30% of the uveitic RRD eyes at presentation in contrast to 12% of the RRD control eyes. In uveitic RRD, the retina was reattached in 59% of eyes with a single operation; the final anatomic reattachment rate was 88%. Finally, a visual acuity of less than 20/200 was present in 71% of the uveitic RRD eyes, 10% of which had no light perception. We discovered a high prevalence of RRD in patients with active panuveitis and infectious uveitis and document that uveitis in itself is a risk factor for the development of RRD. The visual prognosis of RRD in uveitis was poor because of the uveitis itself and the

  1. Experimental results from detached plasmas in TFTR

    International Nuclear Information System (INIS)

    Strachan, J.D.; Boody, F.P.; Bush, C.E.

    1986-10-01

    Detached plasmas are formed in TFTR which have the principal property of the boundary to the high temperature plasma core being defined by a radiating layer. This paper documents the properties of TFTR ohmic-detached plasmas with a range of plasma densities at two different plasma currents

  2. Retinal detachment in black South Africans

    African Journals Online (AJOL)

    Rhegmatogenous retinal detachments seen in black patients attending King Edward VIII Hospital. Ophthalmology Clinic over a 5-year period from January. 1987 to December 1991 were reviewed. Penetrating trauma and diabetic retinopathy were excluded. There were 114 detachments in 112 patients, which gave.

  3. Intraretinal proliferation induced by retinal detachment

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, S.K.; Erickson, P.A.; Lewis, G.P.; Anderson, D.H. (Univ. of California, Santa Barbara (USA))

    1991-05-01

    Cellular proliferation after retinal detachment was studied by {sup 3}H-thymidine light microscopic autoradiography in cats that had experimental detachments of 0.5-180 days duration. The animals underwent labeling 2 hr before death with an intraocular injection of 200 microCi of {sup 3}H-thymidine. The number of labeled nuclei were counted in 1-micron thick tissue sections in regions of detachment, in regions of the experimental eyes that remained attached, and in control eyes that had no detachments. In the normal eye, in one that had only the lens and vitreous removed, and in the eyes with 0.5- and 1-day detachments, the number of labeled nuclei ranged from 0/mm (0.5-day detachment) to 0.38/mm (lens and vitreous removed only). By 2 days postdetachment, the number of labeled nuclei increased to 2.09/mm. The highest levels of labeling occurred in two animals with detachments of 3 (7.86/mm) and 4 (7.09/mm) days. Thereafter, the numbers declined steadily until near-baseline counts were obtained at 14 days. The number of labeled nuclei was slightly elevated in the attached regions of two animals with 3-day detachments. Labeled cell types included: Mueller cells, astrocytes, pericytes, and endothelial cells of the retinal vasculature, and both resident (microglial cells) and invading macrophages. In an earlier study RPE cells were also shown to proliferate in response to detachment. Thus, these data show that proliferation is a rapid response to detachment, reaching a maximum within 4 days, and that virtually every nonneuronal cell type in the retina can participate in this response. The data suggest that events leading to such clinical manifestations as proliferative vitreoretinopathy and subretinal fibrosis may have their beginnings in this very early proliferative response.

  4. Intraretinal proliferation induced by retinal detachment

    International Nuclear Information System (INIS)

    Fisher, S.K.; Erickson, P.A.; Lewis, G.P.; Anderson, D.H.

    1991-01-01

    Cellular proliferation after retinal detachment was studied by 3 H-thymidine light microscopic autoradiography in cats that had experimental detachments of 0.5-180 days duration. The animals underwent labeling 2 hr before death with an intraocular injection of 200 microCi of 3 H-thymidine. The number of labeled nuclei were counted in 1-micron thick tissue sections in regions of detachment, in regions of the experimental eyes that remained attached, and in control eyes that had no detachments. In the normal eye, in one that had only the lens and vitreous removed, and in the eyes with 0.5- and 1-day detachments, the number of labeled nuclei ranged from 0/mm (0.5-day detachment) to 0.38/mm (lens and vitreous removed only). By 2 days postdetachment, the number of labeled nuclei increased to 2.09/mm. The highest levels of labeling occurred in two animals with detachments of 3 (7.86/mm) and 4 (7.09/mm) days. Thereafter, the numbers declined steadily until near-baseline counts were obtained at 14 days. The number of labeled nuclei was slightly elevated in the attached regions of two animals with 3-day detachments. Labeled cell types included: Mueller cells, astrocytes, pericytes, and endothelial cells of the retinal vasculature, and both resident (microglial cells) and invading macrophages. In an earlier study RPE cells were also shown to proliferate in response to detachment. Thus, these data show that proliferation is a rapid response to detachment, reaching a maximum within 4 days, and that virtually every nonneuronal cell type in the retina can participate in this response. The data suggest that events leading to such clinical manifestations as proliferative vitreoretinopathy and subretinal fibrosis may have their beginnings in this very early proliferative response

  5. Retinal detachment associated with traumatic chorioretinal rupture.

    Science.gov (United States)

    Papakostas, Thanos D; Yonekawa, Yoshihiro; Wu, David; Miller, John B; Veldman, Peter B; Chee, Yewlin E; Husain, Deeba; Eliott, Dean

    2014-01-01

    Traumatic chorioretinal rupture, also known as sclopetaria, is a full-thickness break of the choroid and retina caused by a high-velocity projectile striking or passing adjacent to, but not penetrating, the globe. Previous reports have emphasized that retinal detachment seldom occurs, and observation alone has been the recommended management strategy. However, the authors present herein a series of consecutive patients with retinal detachment associated with sclopetaria and provide a literature review of the topic. They recommend that patients with traumatic chorioretinal rupture be monitored closely for the development of retinal detachment during the first few weeks after the injury. Copyright 2014, SLACK Incorporated.

  6. [Intraocular hypertension after retinal detachment surgery].

    Science.gov (United States)

    Muşat, O; Cristescu, R; Coman, Corina; Asandi, R

    2012-01-01

    This papers presents a case of a patient with retinal detachment, 3 days ago operated (posterior vitrectomy, internal tamponament with silicon oil 1000) who developed increased ocular pressure following silicon oil output in the anterior chamber.

  7. Rhegmatogenous retinal detachment following intravitreal ocriplasmin

    NARCIS (Netherlands)

    Madi, Haifa A.; Haynes, Richard J.; Depla, Diana; de la Cour, Morten D.; Lesnik-Oberstein, Sarit; Muqit, Mahi M. K.; Patton, Niall; Price, Nick; Steel, David H. W.

    2016-01-01

    To describe the characteristics and outcomes of patients presenting with rhegmatogenous retinal detachment (RRD) after ocriplasmin (OCP) injection. Retrospective, multi-centre, observational case series with case note review. Eight patients with symptomatic vitreomacular traction (six with

  8. Formation and development of salt crusts on soil surfaces

    KAUST Repository

    Dai, Sheng

    2015-12-14

    The salt concentration gradually increases at the soil free surface when the evaporation rate exceeds the diffusive counter transport. Eventually, salt precipitates and crystals form a porous sodium chloride crust with a porosity of 0.43 ± 0.14. After detaching from soils, the salt crust still experiences water condensation and salt deliquescence at the bottom, brine transport across the crust driven by the humidity gradient, and continued air-side precipitation. This transport mechanism allows salt crust migration away from the soil surface at a rate of 5 μm/h forming salt domes above soil surfaces. The surface characteristics of mineral substrates and the evaporation rate affect the morphology and the crystal size of precipitated salt. In particular, substrate hydrophobicity and low evaporation rate suppress salt spreading.

  9. A mechanical model of retinal detachment

    International Nuclear Information System (INIS)

    Chou, Tom; Siegel, Michael

    2012-01-01

    We present a model of the mechanical and fluid forces associated with exudative retinal detachments where the retinal photoreceptor cells separate, typically from the underlying retinal pigment epithelium (RPE). By computing the total fluid volume flow arising from transretinal, vascular and RPE pump currents, we determine the conditions under which the subretinal fluid pressure exceeds the maximum yield stress holding the retina and RPE together, giving rise to an irreversible, extended retinal delamination. We also investigate localized, blister-like retinal detachments by balancing mechanical tension in the retina with both the retina–RPE adhesion energy and the hydraulic pressure jump across the retina. For detachments induced by traction forces, we find a critical radius beyond which the blister is unstable to growth. Growth of a detached blister can also be driven by inflamed lesions in which the tissue has a higher choroidal hydraulic conductivity, has insufficient RPE pump activity, or has defective adhesion bonds. We determine the parameter regimes in which the blister either becomes unstable to growth, remains stable and finite-sized, or shrinks, allowing possible healing. The corresponding stable blister radius and shape are calculated. Our analysis provides a quantitative description of the physical mechanisms involved in exudative retinal detachments and can help guide the development of retinal reattachment protocols or preventative procedures. (paper)

  10. A mechanical model of retinal detachment

    Science.gov (United States)

    Chou, Tom; Siegel, Michael

    2012-08-01

    We present a model of the mechanical and fluid forces associated with exudative retinal detachments where the retinal photoreceptor cells separate, typically from the underlying retinal pigment epithelium (RPE). By computing the total fluid volume flow arising from transretinal, vascular and RPE pump currents, we determine the conditions under which the subretinal fluid pressure exceeds the maximum yield stress holding the retina and RPE together, giving rise to an irreversible, extended retinal delamination. We also investigate localized, blister-like retinal detachments by balancing mechanical tension in the retina with both the retina-RPE adhesion energy and the hydraulic pressure jump across the retina. For detachments induced by traction forces, we find a critical radius beyond which the blister is unstable to growth. Growth of a detached blister can also be driven by inflamed lesions in which the tissue has a higher choroidal hydraulic conductivity, has insufficient RPE pump activity, or has defective adhesion bonds. We determine the parameter regimes in which the blister either becomes unstable to growth, remains stable and finite-sized, or shrinks, allowing possible healing. The corresponding stable blister radius and shape are calculated. Our analysis provides a quantitative description of the physical mechanisms involved in exudative retinal detachments and can help guide the development of retinal reattachment protocols or preventative procedures.

  11. Sea salt

    OpenAIRE

    Galvis-Sánchez, Andrea C.; Lopes, João Almeida; Delgadillo, Ivone; Rangel, António O. S. S.

    2013-01-01

    The geographical indication (GI) status links a product with the territory and with the biodiversity involved. Besides, the specific knowledge and cultural practices of a human group that permit transforming a resource into a useful good is protected under a GI designation. Traditional sea salt is a hand-harvested product originating exclusively from salt marshes from specific geographical regions. Once salt is harvested, no washing, artificial drying or addition of anti-caking agents are all...

  12. Raised intraocular pressure and recurrence of retinal detachment as complications of external retinal detachment surgery

    International Nuclear Information System (INIS)

    Jawwad, M.; Khan, B.; Shah, M.A.; Qayyum, I.; Aftab, M.; Qayyum, I.

    2015-01-01

    Patients with Rhegmatogenous retinal detachment may develop raised intraocular pressure and recurrence of retinal detachment when they undergo external retinal detachment surgery. The present study was conducted to determine the postoperative rise in intraocular pressure (IOP) and recurrence of retinal detachment. Methods: The present descriptive study was conducted at Eye department of Lady Reading Hospital, Peshawar on 25 patients of both genders from August 2012 to July 2014. Results: Of the 25 patients, 18 (72%) developed raised IOP in the immediate postoperative period; this figure decreased to 12 (48%) at one week. Following medical or surgical intervention in these 12 cases, there was only 1 (4%) case with mildly raised IOP at two weeks postoperative. Five (20%) cases developed recurrent retinal detachment which later resolved with treatment. There were no significant differences by age or gender. Conclusion: External Retinal Detachment Surgery raised intraocular pressure postoperatively and caused recurrence of retinal detachment. These complications were treated medically and surgically with resolution within two weeks. (author)

  13. Phosphate Salts

    Science.gov (United States)

    ... many different combinations of the chemical phosphate with salts and minerals. Foods high in phosphate include dairy products, whole grain cereals, nuts, and certain meats. Phosphates found in dairy products ... People use phosphate salts for medicine. Be careful not to confuse phosphate ...

  14. Spectroscopic investigations of divertor detachment in TCV

    Directory of Open Access Journals (Sweden)

    K. Verhaegh

    2017-08-01

    The inferred magnitude of recombination is small compared to the target ion current at the time detachment (particle flux drop starts at the target. However, recombination may be having more localized effects (to a flux tube which we cannot discern at this time. Later, at the highest densities achieved, the total recombination does reach levels similar to the particle flux.

  15. [Retinal detachment with retinoschisis--case report].

    Science.gov (United States)

    Cristescu, R; Muşat, O; Toma, Oana; Coma, Corina; Gabej, Ioana; Burcea, M

    2013-01-01

    We present the case of a 43 year old patient diagnosed with rhegmatogenous retinal detachment and retinoschizis, a rare case of disease association. Surgery is recommended and we practice 23 gauge vitrectomy, laser retinopexy, criopexy in the periphery and internal heavy oil tamponade. Postoperatory evolution was favorable.

  16. Shoreline response to detached breakwaters in prototype

    NARCIS (Netherlands)

    Khuong, T.C.

    2016-01-01

    An accurate prediction of shoreline changes behind detached breakwaters is, in regard to the adjustment to the environmental impact, still a challenge for designers and coastal managers. This research is expected to fill the gaps in the estimation of shoreline changes by developing new and

  17. Repair of Traumatic Rhegmatogenous Retinal Detachment Combined with Congenital Falciform Retinal Detachment

    Directory of Open Access Journals (Sweden)

    Fukutaro Mano

    2018-01-01

    Full Text Available Purpose: To report a case of surgical repair of traumatic rhegmatogenous retinal detachment combined with congenital falciform retinal detachment (FRD. Methods: A retrospective case report. Results: A 36-year-old man with traumatic rhegmatogenous retinal detachment complicating a previously known FRD was successfully treated despite residual FRD following pars plana lensectomy, vitrectomy, and encircling scleral buckling. His best corrected visual acuity improved from hand motion at 50 cm to 20/1,000. Conclusion: We concluded that the root of the FRD is susceptible to trauma because of the contraction of fibrovascular tissue. The early intervention of modern vitrectomy to traumatic rhegmatogenous retinal detachment complicating a previously known FRD is an important consideration for enhanced quality of care and optimal patient outcomes.

  18. Salt cookbook

    CERN Document Server

    Saha, Anirban

    2015-01-01

    If you are a professional associated with system and infrastructure management, looking at automated infrastructure and deployments, then this book is for you. No prior experience of Salt is required.

  19. WIDE-FIELD INFRARED IMAGING: A Descriptive Review of Characteristics of Retinoschisis, Retinal Detachment, and Schisis Detachments.

    Science.gov (United States)

    Ho, Vincent Y; Wehmeier, Jarrod M; Shah, Gaurav K

    2016-08-01

    Retinoschisis and retinal detachments are primarily differentiated based on characteristic examination findings. In diagnostically challenging cases, noncontact wide-field infrared imaging can help diagnosis and visualize the extent/margins of retinoschisis, retinal detachment, or combined schisis detachments by comparing reflectivity patterns. This is a retrospective, observational, descriptive case series of 14 eyes of 14 nonconsecutive patients, ranging from 28 to 89 years old (mean 61), diagnosed with retinoschisis, retinal detachment, or schisis detachment from May 5, 2014 to March 4, 2015. Patients with secondary retinoschisis and/or retinal detachment from other causes were not included in the study. Heidelberg Wide-Field Module lens and Heidelberg Spectralis HRA+OCT machine (Heidelberg Engineering, Heidelberg, Germany) were used to obtain noncontact, wide-field infrared images on each study eye. Seven eyes with retinal detachments, four with retinoschises, and three with schisis detachments were imaged using this novel wide-field infrared technique. Retinoschisis appears light and translucent with prominent vasculature, retinal detachments appear dark and opaque, and combined retinoschisis/retinal detachment exhibit mixed reflectivity patterns. Wide-field infrared imaging provides a quick, noncontact, noninvasive method to accurately diagnose and to monitor for progression of retinoschisis, retinal detachment, or combined schisis detachments.

  20. Rhegmatogenous retinal detachment and conventional surgical treatment.

    Science.gov (United States)

    Golubovic, M

    2013-01-01

    The aim of the paper was to present the efficacy and indications for application of conventional surgical treatment of retinal detachment by using external implants, that is,application of encircling band and buckle. This study comprised patients from the University Eye Clinic in Skopje. A total of 33 patients were diagnosed and surgically treated in the period between May 2010 and August 2011. Conventional surgery was applied in smaller number of patients whose changes of the vitreous body were manifested by detachment of posterior hyaloid membrane, syneresis, with appearance of a small number of pigment cells in the vitreous body and synchysis, and the very retina was with fresh detachment without folds or epiretinal changes (that is, PVR A grade). There were a larger number of patients with more distinct proliferative changes of the vitreous body and of the retina, grades PVR B to C1-C2, and who also underwent the same surgical approach. Routine ophthalmologic examinations were performed, including: determination of visual acuity by Snellen's optotypes, determination of eye pressure with Schiotz's tonometer, examination of anterior segment on biomicroscopy, indirect biomicroscopy of posterior eye segment (vitreous body and retina) and examination on biomicroscopy with Goldmann prism, B scan echography of the eyes before and after surgical treatment. Conventional treatment was used by external application of buckle or application of buckle and encircling band. In case of one break, radial buckle was applied and in case of multiple breaks in one quadrant limbus parallel buckle was applied. Besides buckle, encircling band was applied in patients with total or subtotal retinal detachment with already present distinct changes in the vitreous body (PVR B or C1-C2) and degenerative changes in the vitreous body. Breaks were closed with cryopexy. The results obtained have shown that male gender was predominant and that the disease was manifested in younger male adults

  1. Identifying subsurface detachment defects by acoustic tracing

    Czech Academy of Sciences Publication Activity Database

    Sklodowski, R.; Drdácký, Miloš; Sklodowski, M.

    2013-01-01

    Roč. 56, June (2013), s. 56-64 ISSN 0963-8695 R&D Projects: GA ČR(CZ) GBP105/12/G059 Institutional support: RVO:68378297 Keywords : acoustic excitation * plaster detachment defects * frequency response * inspection systems * signal processing Subject RIV: JN - Civil Engineering Impact factor: 1.717, year: 2013 http://www.sciencedirect.com/science/article/pii/S0963869513000303

  2. Tonic shock induces detachment of Giardia lamblia.

    Directory of Open Access Journals (Sweden)

    Wendy R Hansen

    Full Text Available BACKGROUND: The parasite Giardia lamblia must remain attached to the host small intestine in order to proliferate and subsequently cause disease. However, little is known about the factors that may cause detachment in vivo, such as changes in the aqueous environment. Osmolality within the proximal small intestine can vary by nearly an order of magnitude between host fed and fasted states, while pH can vary by several orders of magnitude. Giardia cells are known to regulate their volume when exposed to changes in osmolality, but the short-timescale effects of osmolality and pH on parasite attachment are not known. METHODOLOGY AND PRINCIPAL FINDINGS: We used a closed flow chamber assay to test the effects of rapid changes in media osmolality, tonicity, and pH on Giardia attachment to both glass and C2(Bbe-1 intestinal cell monolayer surfaces. We found that Giardia detach from both surfaces in a tonicity-dependent manner, where tonicity is the effective osmolality experienced by the cell. Detachment occurs with a characteristic time constant of 25 seconds (SD = 10 sec, n = 17 in both hypo- and hypertonic media but is otherwise insensitive to physiologically relevant changes in media composition and pH. Interestingly, cells that remain attached are able to adapt to moderate changes in tonicity. By exposing cells to a timed pattern of tonicity variations and adjustment periods, we found that it is possible to maximize the tonicity change experienced by the cells, overcoming the adaptive response and resulting in extensive detachment. CONCLUSIONS AND SIGNIFICANCE: These results, conducted with human-infecting Giardia on human intestinal epithelial monolayers, highlight the ability of Giardia to adapt to the changing intestinal environment and suggest new possibilities for treatment of giardiasis by manipulation of tonicity in the intestinal lumen.

  3. The prognosis of retinal detachment due to lattice degeneration.

    Science.gov (United States)

    Benson, W E; Morse, P H

    1978-09-01

    In a series of 553 consecutive retinal detachments, 29% (120) were due to lattice degeneration. Forty-five percent of these were due to atrophic holes in the lattice degeneration and 55% were due to tears caused by traction posterior to or at the end of a patch of lattice. In phakic patients, retinal detachments due to atrophic holes were most common in young myopes. Detachments due to traction tears were seen in older, less myopic patients. The incidence of massive periretinal proliferation was less (5%) in detachments due to lattice degeneration than in detachments not due to lattice degeneration (6.5%).

  4. Fibrinogen and rhegmatogenous retinal detachment: a pilot prospective study.

    Science.gov (United States)

    Theocharis, Ip

    2010-02-18

    To examine the correlation, if any, between fibrinogen plasma levels (FPL) and the clinical features of rhegmatogenous retinal detachment (RRD). FPL were measured preoperatively in 33 patients with primary RRD. Patient characteristics and detachment features such as the numbers of breaks and the extent of the detachment were recorded; No statistically significant correlation was found between FPL and the number of breaks. A statistically significant correlation was found between FPL and the extent of the RRD, even if the influence of the number of breaks was excluded. FPL correlate with retinal detachment extent, which implicates an acute inflammatory response to detachment traumatic phenomenon or a role of the fibrinogen molecule in retinal adhesiveness.

  5. The seasonal cycle of Titan's detached haze

    Science.gov (United States)

    West, Robert A.; Seignovert, Benoît; Rannou, Pascal; Dumont, Philip; Turtle, Elizabeth P.; Perry, Jason; Roy, Mou; Ovanessian, Aida

    2018-04-01

    Titan's `detached' haze, seen in Voyager images in 1980 and 1981 and monitored by the Cassini Imaging Science Subsystem (ISS) during the period 2004-2017, provides a measure of seasonal activity in Titan's mesosphere with observations over almost half of Saturn's seasonal cycle. Here we report on retrieved haze extinction profiles that reveal a depleted layer (having a diminished aerosol content), visually manifested as a gap between the main haze and a thin, detached upper layer. Our measurements show the disappearance of the feature in 2012 and its reappearance in 2016, as well as details after the reappearance. These observations highlight the dynamical nature of the detached haze. The reappearance seems congruent with earlier descriptions by climate models but more complex than previously described. It occurs in two steps, first as haze reappearing at 450 ± 20 km and one year later at 510 ± 20 km. These observations provide additional tight and valuable constraints about the underlying mechanisms, especially for Titan's mesosphere, that control Titan's haze cycle.

  6. [Scleral buckling for inferior rhegmatogenous retinal detachments].

    Science.gov (United States)

    Abdellaoui, M; Chraibi, F; Benatiya Andaloussi, I; Tahri, H

    2014-10-01

    To investigate the epidemiological, clinical, therapeutic and prognostic factors in cases of inferior rhegmatogenous retinal detachments (RD) treated by scleral buckling surgery. A retrospective chart review was performed on 45 patients (45 eyes) with inferior RD with only inferior tears (4:00-8:00), who had been treated by scleral buckling surgery over a 6-year period from 2006 to 2011. The parameters studied included patient demographics, refractive status, time until consultation, clinical exam data, treatment modalities and functional and anatomic results. Forty-five cases were included in this study (45 eyes), with an average patient age of 44.5 years (14 to 75 years) and a slight male predominance (56%). Myopia was observed in 60%. Mean time until consultation was 3.5 months. Visual acuity on admission was less than 1/10 in 53.33%. Macular detachment was found in 80%. Causative lesions were holes in 26 eyes. Proliferative vitreoretinopathy was essentially stage B in 48.9%. Scleral buckling surgery was performed in all patients, with drainage of subretinal fluid in 37.8%. Retinal reattachment was obtained in 36 eyes (80%) with a final visual acuity greater than or equal to 1/10 in 71.11%. The mean follow-up in our study was 6.62 months. Inferior retinal detachment has a predilection for young myopes. The time until consultation is often long, and extraocular surgery, although difficult, exhibits documented efficacy. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  7. RhoA Signaling and Synaptic Damage Occur Within Hours in a Live Pig Model of CNS Injury, Retinal Detachment

    Science.gov (United States)

    Wang, Jianfeng; Zarbin, Marco; Sugino, Ilene; Whitehead, Ian; Townes-Anderson, Ellen

    2016-01-01

    Purpose The RhoA pathway is activated after retinal injury. However, the time of onset and consequences of activation are unknown in vivo. Based on in vitro studies we focused on a period 2 hours after retinal detachment, in pig, an animal whose retina is holangiotic and contains cones. Methods Under anesthesia, retinal detachments were created by subretinal injection of a balanced salt solution. Two hours later, animals were sacrificed and enucleated for GTPase activity assays and quantitative Western blot and confocal microscopy analyses. Results RhoA activity with detachment was increased 1.5-fold compared to that in normal eyes or in eyes that had undergone vitrectomy only. Increased phosphorylation of myosin light chain, a RhoA effector, also occurred. By 2 hours, rod cells had retracted their terminals toward their cell bodies, disrupting the photoreceptor-to-bipolar synapse and producing significant numbers of spherules with SV2 immunolabel in the outer nuclear layer of the retina. In eyes with detachment, distant retina that remained attached also showed significant increases in RhoA activity and synaptic disjunction. Increases in RAC1 activity and glial fibrillary acidic protein (GFAP) were not specific for detachment, and sprouting of bipolar dendrites, reported for longer detachments, was not seen. The RhoA kinase inhibitor Y27632 significantly reduced axonal retraction by rod cells. Conclusions Activation of the RhoA pathway occurs quickly after injury and promotes synaptic damage that can be controlled by RhoA kinase inhibition. We suggest that retinal detachment joins the list of central nervous system injuries, such as stroke and spinal cord injury, that should be considered for rapid therapeutic intervention. PMID:27472075

  8. Numerical computational of fluid flow through a detached retina

    Science.gov (United States)

    Jiann, Lim Yeou; Ismail, Zuhaila; Shafie, Sharidan; Fitt, Alistair

    2015-02-01

    In this paper, a phenomenon of fluid flow through a detached retina is studied. Rhegmatogeneous retinal detachment happens when vitreous humour flow through a detached retina. The exact mechanism of Rhegmatogeneous retinal detachment is complex and remains incomplete. To understand the fluid flow, a paradigm mathematical model is developed and is approximated by the lubrication theory. The numerical results of the velocity profile and pressure distribution are computed by using Finite Element Method. The effects of fluid mechanical on the retinal detachment is discussed and analyzed. Based on the analysis, it is found that the retinal detachment deformation affects the pressure distribution. It is important to comprehend the development of the retinal detachment so that a new treatment method can be developed.

  9. Mediterranean detachment zones : thermicity vs heritage.

    Science.gov (United States)

    Labrousse, Loic; Huet, Benjamin; Le Pourhiet, Laetitia; Jolivet, Laurent; Burov, Evgenii

    2017-04-01

    Even if the seminal comprehensive descriptions of Metamorphic Core Complexes (MCCs) in the American Cordillera mentionned lower plates constituted of gneiss and intruded by granites (e. g. Snake Range, Whipple Mountains), the actual definition of MCCs : « Cordilleran metamorphic core complexes appear to be bodies from the middle crust that have been dragged out from beneath fracturing and extending upper crustal rocks, and exposed beneath shallow-dipping (normal slip) faults of large areal extent » {as in Lister & Davis, 1989, Journal of Structural Geology, v. 11, pp. 65-94} refers to rocks exhumed from the middle crust whatever their thermal history. The fundamental property of this middle crust resides in its ability fo flow lateraly toward the forming dome, to accommodate stretching of the upper plate and preserve a relatively flat moho. Even though thermal reequilibration can induce weakening of the lower crust, a similar strength profile can also be inherited from pre-extension evolution of the continental crust and promote development of the original structure of MCCs : their detachment. In order to unravel the rheological meaning of detachments, we propose here a review of extensional shear zones described as detachments in the Mediterranean realm, and establish a three end-members typology with « hot MCCs » as one end-member, and two cold MCC end-members with a weak middle crust due to stacking of high pressure metapelitic nappes or a strong upper crust responsible for the strength contrast exaggeration between the upper and lower crust. New fully coupled thermo-mechanical modeling experiments together with a review of comparable published results allow to test this three end-member typology and determine the critical strength constrast for the perennial development of a detachment zone. A 1000 ratio between the strength at the brittle-ductile transition and the strength at the base of the crust seems a boundary value between localized extensional modes

  10. Bath Salts

    Science.gov (United States)

    ... to get the same high, and feel withdrawal symptoms when they stop. People who abuse bath salts may feel driven to do whatever they can to keep getting high, including taking risks. Users can also develop what is called "excited delirium." When this happens, people get dehydrated , their muscle ...

  11. Kinematic evidence for downdip movement on the Mormon Peak detachment

    Science.gov (United States)

    Walker, Christopher D.; Anders, Mark H.; Christie-Blick, Nicholas

    2007-03-01

    The Mormon Peak detachment is considered to be one of the best examples of a rooted upper crustal detachment fault that propagated through the brittle crust at a low angle. The hanging wall of the detachment today consists of a number of isolated blocks that have been interpreted as remnants of a once-contiguous extensional allochthon. Here we present the results of a new study of directional indicators from the basal surfaces beneath these blocks. These measurements do not agree with the long-standing interpretation of a S75°W movement direction for the detachment hanging wall. Instead, the most recent movement on each section of the detachment took place approximately parallel to the present downdip direction. We conclude that the Mormon Peak detachment is best explained as the basal surfaces to a series of rootless gravity slides.

  12. Fibrinogen and rhegmatogenous retinal detachment: a pilot prospective study

    Directory of Open Access Journals (Sweden)

    IP Theocharis

    2010-02-01

    Full Text Available IP TheocharisOphthalmology Department, Iaso General Hospital, Athens, GreecePurpose: To examine the correlation, if any, between fibrinogen plasma levels (FPL and the clinical features of rhegmatogenous retinal detachment (RRD.Methods: FPL were measured preoperatively in 33 patients with primary RRD. Patient characteristics and detachment features such as the numbers of breaks and the extent of the detachment were recorded;Results: No statistically significant correlation was found between FPL and the number of breaks. A statistically significant correlation was found between FPL and the extent of the RRD, even if the influence of the number of breaks was excluded. Conclusions: FPL correlate with retinal detachment extent, which implicates an acute inflammatory response to detachment traumatic phenomenon or a role of the fibrinogen molecule in retinal adhesiveness.Keywords: fibrinogen, retinal detachment, pathogenesis

  13. Structural recovery of the detached macula after retinal detachment repair as assessed by optical coherence tomography.

    Science.gov (United States)

    Joe, Soo Geun; Kim, Yoon Jeon; Chae, Ju Byung; Yang, Sung Jae; Lee, Joo Yong; Kim, June-Gone; Yoon, Young Hee

    2013-06-01

    To investigate correlations between preoperative and postoperative foveal microstructures in patients with macula-off rhegmatogenous retinal detachment (RRD). We reviewed the records of 31 eyes from 31 patients with macula-off RRD who had undergone successful re-attachment surgery. We analyzed data obtained from complete ophthalmologic examinations and optical coherence tomography (OCT) before and 9 to 12 months after surgery. All postoperative OCT measurements were taken with spectral-domain OCT, but a subset of preoperative OCT measurements were taken with time-domain OCT. The mean duration of macular detachment was 15.5 ± 15.2 days, and mean preoperative best-corrected visual acuity (BCVA, logarithm of the minimum angle of resolution) was 1.03 ± 0.68. Preoperative visual acuity was correlated with retinal detachment height (p macula-off duration. The final BCVA was significantly correlated with integrity of the junction between the photoreceptor inner and outer segments (IS/OS) combined with the continuity of external limiting membrane (ELM) (p = 0.025). The presence of IRS and OLU on a detached macula were highly correlated with the final postoperative integrity of the IS/OS junction and the ELM (p = 0.017). Eyes preoperatively exhibiting IRS and OLU showed a higher incidence of disruption to the photoreceptor IS/OS junction and the ELM at final follow-up. Such a close correlation between preoperative and postoperative structural changes may explain why ultimate visual recovery in such eyes is poor.

  14. Detection of detachments and inhomogeneities in frescos by Compton scattering

    International Nuclear Information System (INIS)

    Castellano, A.; Cesareo, R.; Buccolieri, G.; Donativi, M.; Palama, F.; Quarta, S.; De Nunzio, G.; Brunetti, A.; Marabelli, M.; Santamaria, U.

    2005-01-01

    A mobile instrument has been developed for the detection and mapping of detachments in frescos by using Compton back scattered photons. The instrument is mainly composed of a high energy X-ray tube, an X-ray detection system and a translation table. The instrument was first applied to samples simulating various detachment situations, and then transferred to the Vatican Museum to detect detachments and inhomogeneities in the stanza di Eliodoro, one of the 'Raphael's stanze'

  15. Detection of detachments and inhomogeneities in frescos by Compton scattering

    Energy Technology Data Exchange (ETDEWEB)

    Castellano, A. [Dipartimento di Scienza dei Materiali, Universita di Lecce, 73100 Lecce (Italy); INFN, Sezione di Lecce, via per Arnesano, 73100 Lecce (Italy); Cesareo, R. [Istituto di Matematica e Fisica, Universita di Sassari, 07100 Sassari (Italy) and INFN, Sezione di Cagliari, Cittadella Universitaria di Monserrato, 09042 Cagliari (Italy)]. E-mail: cesareo@uniss.it; Buccolieri, G. [Dipartimento di Scienza dei Materiali, Universita di Lecce, 73100 Lecce (Italy); INFN, Sezione di Lecce, via per Arnesano, 73100 Lecce (Italy); Donativi, M. [Dipartimento di Scienza dei Materiali, Universita di Lecce, 73100 Lecce (Italy); Palama, F. [Dipartimento di Scienza dei Materiali, Universita di Lecce, 73100 Lecce (Italy); INFN, Sezione di Lecce, via per Arnesano, 73100 Lecce (Italy); Quarta, S. [Dipartimento di Scienza dei Materiali, Universita di Lecce, 73100 Lecce (Italy); INFN, Sezione di Lecce, via per Arnesano, 73100 Lecce (Italy); De Nunzio, G. [Dipartimento di Scienza dei Materiali, Universita di Lecce, 73100 Lecce (Italy); INFN, Sezione di Lecce, via per Arnesano, 73100 Lecce (Italy); Brunetti, A. [Istituto di Matematica e Fisica, Universita di Sassari, 07100 Sassari (Italy); INFN, Sezione di Cagliari, Cittadella Universitaria di Monserrato, 09042 Cagliari (Italy); Marabelli, M. [Istituto Centrale del Restauro, P.zza S. Francesco di Paola, 00184 Rome (Italy); Santamaria, U. [Laboratori dei Musei Vaticani, Citta del Vaticano, Rome (Italy)

    2005-07-01

    A mobile instrument has been developed for the detection and mapping of detachments in frescos by using Compton back scattered photons. The instrument is mainly composed of a high energy X-ray tube, an X-ray detection system and a translation table. The instrument was first applied to samples simulating various detachment situations, and then transferred to the Vatican Museum to detect detachments and inhomogeneities in the stanza di Eliodoro, one of the 'Raphael's stanze'.

  16. Meniscus Shapes in Detached Bridgman Growth

    Science.gov (United States)

    Volz, M. P.; Mazuruk, K

    2010-01-01

    In detached Bridgman crystal growth, most of the melt is in contact with the ampoule wall, but the crystal is separated from the wall by a small gap, typically 1-100 micrometers. A liquid free surface, or meniscus, bridges across this gap at the position of the melt-crystal interface. Meniscus shapes have been calculated for the case of detached Bridgman growth in cylindrical ampoules by solving the Young-Laplace equation. Key parameters affecting meniscus shapes are the growth angle, contact angle of the meniscus to the ampoule wall, the pressure differential across the meniscus, and the Bond number, a measure of the ratio of gravitational to capillary forces. In general, for specified values of growth and contact angles, solutions exist only over a finite range of pressure differentials. For intermediate values of the Bond number, there are multiple solutions to the Young-Laplace equations. There are also cases where, as a function of pressure differential, existence intervals alternate with intervals where no solutions exist. The implications of the meniscus shape calculations on meniscus stability are discussed.

  17. Extent of Detached Retina and Lens Status Influence Intravitreal Protein Expression in Rhegmatogenous Retinal Detachment.

    Science.gov (United States)

    Pollreisz, Andreas; Sacu, Stefan; Eibenberger, Katharina; Funk, Marion; Kivaranovic, Danijel; Zlabinger, Gerhard J; Georgopoulos, Michael; Schmidt-Erfurth, Ursula

    2015-08-01

    The aim of the study was to compare intravitreal cytokines and chemokines to clinical parameters in patients with rhegmatogenous retinal detachment (RRD). In this prospective study vitreous samples were taken undiluted from 60 patients with RRD and 20 age-matched controls with idiopathic epiretinal membranes at the beginning of primary vitrectomy. The following clinical parameters were assessed from RRD patients prior to surgery: number of quadrants detached, RD height, lens status, symptom duration, and refractive power. Concentrations of 40 different proteins in the vitreous of RRD eyes were measured by multiplex protein array, compared with controls and correlated to clinical parameters. Ten cytokines and chemokines were significantly upregulated in the vitreous of RRD eyes compared with controls (tissue inhibitors of metalloproteinases [TIMP]-1 and -2, macrophage inflammatory protein [MIP]-1α, monocyte chemoattractant protein [MCP]-1, IL-6, and -8, inducible protein (IP)-10, brain-derived neurotrophic factor [BDNF], TGFβ-3, and platelet-derived growth factor [PDGF]-AB/BB). Linear regression analysis revealed that IL-8 and TGFβ-3 increased with the number of retinal quadrants detached, while TIMP-1 rose in eyes with greater RD heights. Concentrations of IP-10 and myeloperoxidase (MPO) peaked in eyes with two or more quadrants detached, while TIMP-2 was highest expressed in the vitreous of eyes with great RD height. In pseudophakic eyes with higher detachment height levels of vascular cell adhesion molecule (VCAM)-1 were significantly increased, while neural cell adhesion molecule (NCAM) was decreased in pseudophakic patients with shallow RD height. Extent of RRD and lens status significantly influence intravitreal proinflammatory, profibrotic, and proapoptotic protein expression. These data contribute to the fundamental understanding of pathophysiological mechanisms in RRD and may serve as a basis for development of adjunct therapeutics to facilitate

  18. Risk of retinal detachment in patients with lattice degeneration.

    Science.gov (United States)

    Sasaki, K; Ideta, H; Yonemoto, J; Tanaka, S; Hirose, A; Oka, C

    1998-01-01

    To determine the risk of retinal detachment in patients with lattice degeneration of the retina, we statistically analyzed the incidence of retinal detachment in these patients. The data of hospital patients with retinal detachment associated with lattice degeneration in Kumamoto Prefecture, Japan, in 1990 were collected. The prevalence of lattice degeneration in Kumamoto was reported to be 9.5% in 1980. Based on population data from the 1990 census, the cumulative incidence of retinal detachment associated with lattice degeneration was calculated in this study. Among 1,840,000 residents in Kumamoto, there were 110 patients with retinal detachment associated with lattice degeneration; 72 with detachment resulting from tractional tears (tears), and 38 with detachment from atrophic holes. The cumulative incidence of retinal detachment from atrophic holes was 1.5% at the age of 40 years; from tears it was 3.6% at the age of 80 years. The cumulative incidence of detachment from both atrophic holes and tears was 5.3% at the age of 80 years. The results of this study are useful for clarifying the natural course of lattice degeneration.

  19. Functional Detachment of Totalitarian Nazi Architecture

    Science.gov (United States)

    Antoszczyszyn, Marek

    2017-10-01

    The paper describes the systematization process of architectural styles in use during Nazi period in Germany between 1933-45. In the results of the research some regularity about strict concern between function & styling has been observed. Using comparison & case study as well as analytical methods there were pointed out characteristic features of more than 500 objects’ architectural appearance that helped to specify their styling & group them into architectural trends. Ultimately the paper proves that the found trends of architectural styling could be collected by functional detachment key. This observation explains easy to recognize even nowadays traceability – so characteristic to Nazi German architecture. Facing today pluralism in architecture, the findings could be a helpful key in the organization of spatial architectural identification process.

  20. Maritime Training Serbian Autonomous Vessel Protection Detachment

    Directory of Open Access Journals (Sweden)

    Šoškić Svetislav D.

    2014-06-01

    Full Text Available The crisis in Somalia has caused appearance of piracy at sea in the Gulf of Aden and the Western Indian Ocean. Somali pirates have become a threat to economic security of the world because almost 30 percent of world oil and 20 percent of global trade passes through the Gulf of Aden. Solving the problem of piracy in this part of the world have included international organizations, institutions, military alliances and the states, acting in accordance with international law and UN Security Council resolutions. The European Union will demonstrate the application of a comprehensive approach to solving the problem of piracy at sea and the crisis in Somalia conducting naval operation — EU NAVFOR Atalanta and operation EUTM under the Common Security and Defense Policy. The paper discusses approaches to solving the problem of piracy in the Gulf of Aden and the crisis in Somalia. Also, the paper points to the complexity of the crisis in Somalia and dilemmas correctness principles that are applied to solve the problem piracy at sea. One of goals is protections of vessels of the World Food Programme (WFP delivering food aid to displaced persons in Somalia. Republic of Serbia joined in this mission and trained and sent one a autonomous team in this military operation for protection WFP. This paper consist the problem of modern piracy, particularly in the area of the Horn of Africa became a real threat for the safety of maritime ships and educational process of Serbian Autonomous vessel protection detachment. Serbian Military Academy adopted and developed educational a training program against piracy applying all the provisions and recommendations of the IMO conventions and IMO model courses for Serbian Autonomous vessel protection detachment.

  1. Missed retinal breaks in rhegmatogenous retinal detachment

    Directory of Open Access Journals (Sweden)

    Brijesh Takkar

    2016-12-01

    Full Text Available AIM: To evaluate the causes and associations of missed retinal breaks (MRBs and posterior vitreous detachment (PVD in patients with rhegmatogenous retinal detachment (RRD. METHODS: Case sheets of patients undergoing vitreo retinal surgery for RRD at a tertiary eye care centre were evaluated retrospectively. Out of the 378 records screened, 253 were included for analysis of MRBs and 191 patients were included for analysis of PVD, depending on the inclusion criteria. Features of RRD and retinal breaks noted on examination were compared to the status of MRBs and PVD detected during surgery for possible associations. RESULTS: Overall, 27% patients had MRBs. Retinal holes were commonly missed in patients with lattice degeneration while missed retinal tears were associated with presence of complete PVD. Patients operated for cataract surgery were significantly associated with MRBs (P=0.033 with the odds of missing a retinal break being 1.91 as compared to patients with natural lens. Advanced proliferative vitreo retinopathy (PVR and retinal bullae were the most common reasons for missing a retinal break during examination. PVD was present in 52% of the cases and was wrongly assessed in 16%. Retinal bullae, pseudophakia/aphakia, myopia, and horse shoe retinal tears were strongly associated with presence of PVD. Traumatic RRDs were rarely associated with PVD. CONCLUSION: Pseudophakic patients, and patients with retinal bullae or advanced PVR should be carefully screened for MRBs. Though Weiss ring is a good indicator of PVD, it may still be over diagnosed in some cases. PVD is associated with retinal bullae and pseudophakia, and inversely with traumatic RRD.

  2. Use of ocular ultrasound for the evaluation of retinal detachment.

    Science.gov (United States)

    Shinar, Zachary; Chan, Linda; Orlinsky, Michael

    2011-01-01

    Retinal detachment is an ocular emergency posing diagnostic difficulty for the emergency practitioner. Direct fundoscopy and visual field testing are difficult to perform and do not completely rule out retinal detachment. Ophthalmologists use ocular ultrasound to enhance their clinical acumen in detecting retinal detachments (RD), and bedside ultrasound capability is readily available to many emergency practitioners (EP). Our study sought to assess whether ocular ultrasound would be a helpful adjunct for the diagnosis of RD for the practicing EP. This was a prospective observational study with a convenience sample of patients. As part of a general course on emergency ultrasonography, practitioners received a 30-min training session on ocular ultrasound before beginning the study. Trained practitioners submitted ultrasound scans with interpretation on patients with signs and symptoms consistent with retinal detachment. Thirty-one of the 72 practitioners trained submitted ocular ultrasound reports on patients presenting to the Emergency Department with concerns for retinal detachments. EPs achieved a 97% sensitivity (95% confidence interval [CI] 82-100%) and 92% specificity (95% CI 82-97%) on 92 examinations (29 retinal detachments). Disc edema and vitreous hemorrhage accounted for false positives, and a subacute retinal detachment accounted for the only false negative. These data show that trained emergency practitioners can use ocular ultrasound as an adjunct to their clinical assessment for retinal detachment. Copyright © 2011 Elsevier Inc. All rights reserved.

  3. Risk of Retinal Detachment After Pediatric Cataract Surgery

    DEFF Research Database (Denmark)

    Haargaard, Birgitte; Andersen, Elisabeth W; Oudin, Anna

    2014-01-01

    was based on medical chart review. RESULTS: Among 1043 eyes of 656 children undergoing surgery for pediatric cataract, 25 eyes (23 children) developed retinal detachment at a median time of 9.1 years after surgery. The overall 20-year risk of retinal detachment was 7% (95% confidence interval [CI]: 3...

  4. Frictional and elastic energy in gecko adhesive detachment.

    Science.gov (United States)

    Gravish, Nick; Wilkinson, Matt; Autumn, Kellar

    2008-03-06

    Geckos use millions of adhesive setae on their toes to climb vertical surfaces at speeds of over 1 m s(-1). Climbing presents a significant challenge for an adhesive since it requires both strong attachment and easy, rapid removal. Conventional pressure-sensitive adhesives are either strong and difficult to remove (e.g. duct tape) or weak and easy to remove (e.g. sticky notes). We discovered that the energy required to detach adhering tokay gecko setae (W(d)) is modulated by the angle (theta) of a linear path of detachment. Gecko setae resist detachment when dragged towards the animal during detachment (theta = 30 degrees ) requiring W(d) = 5.0+/-0.86(s.e.) J m(-2) to detach, largely due to frictional losses. This external frictional loss is analogous to viscous internal frictional losses during detachment of pressure-sensitive adhesives. We found that, remarkably, setae possess a built-in release mechanism. Setae acted as springs when loaded in tension during attachment and returned elastic energy when detached along the optimal path (theta=130 degrees ), resulting in W(d) = -0.8+/-0.12 J m(-2). The release of elastic energy from the setal shaft probably causes spontaneous release, suggesting that curved shafts may enable easy detachment in natural, and synthetic, gecko adhesives.

  5. Risk of progression in macula-on rhegmatogenous retinal detachment.

    Science.gov (United States)

    Callizo, Josep; Pfeiffer, Sebastian; Lahme, Eva; van Oterendorp, Christian; Khattab, Mohammed; Bemme, Sebastian; Kulanga, Miroslav; Hoerauf, Hans; Feltgen, Nicolas

    2017-08-01

    To identify factors that may lead to a rapid progression in macula-on rhegmatogenous retinal detachment (RRD), in particular, those that may lead to macular involvement. Observational, prospective, single-center study. Patients referred for surgery due to primary rhegmatogenous retinal detachment with the macula on between 2009 and 2013 were included. Relevant factors analyzed included age, time delay until surgery, lens status, myopia, the detachment's location and configuration as well as number, size and type of retinal breaks. Eyes underwent optical coherence tomography to detect macular detachment. A multivariate analysis was performed to investigate the effect of several factors in the progression of retinal detachment. A total of 116 eyes of 116 patients were included. Mean time delay between admission and surgery was 1.8 ± 1.4 days. Progression was observed in 19.8% of the eyes. Of those, 47.8% presented macular detachment. Ten of the 11 (90.9%) eyes presenting progression involving the macula also exhibited a bullous configuration, which was the only parameter that correlated significantly with detachment progression in patients with (p = 0.0036) and without (p = 0.0014) macular involvement. For the first time in a prospective trial, a bullous configuration was found to be a highly significant predictor for progression in macula-on detachments. Our data support prompt surgery in patients diagnosed with bullous macula-on RRD.

  6. DETACHMENT OF HUMAN FIBROBLASTS FROM FEP-TEFLON SURFACES

    NARCIS (Netherlands)

    VANKOOTEN, TG; SCHAKENRAAD, JM; VANDERMEI, HC; BUSSCHER, HJ

    1991-01-01

    In this study a comparison is made between the detachment behavior of human fibroblasts adhered to hydrophobic FEP-Teflon (water contact angle 109 degrees) and to hydrophilic glass (water contact angle smaller than 15 degrees) during exposure to a laminar, incrementally loaded flow. Detachment from

  7. Recalcitrance of Streptococcus mutans biofilms towards detergent-stimulated detachment

    NARCIS (Netherlands)

    Landa, AS; van de Belt-Gritter, B; van der Mei, HC; Busscher, HJ

    The biofilm mode of growth protects the plaque microorganisms against environmental attacks, such as from antimicrobials or detergents. Detergents have a demonstrated ability to detach initially adhering bacteria from enamel surfaces, but the ability of detergent components to detach plaque bacteria

  8. MACULAR DETACHMENT ASSOCIATED WITH INTRACHOROIDAL CAVITATION IN NONPATHOLOGICAL MYOPIC EYES.

    Science.gov (United States)

    Ando, Yoshimasa; Inoue, Makoto; Ohno-Matsui, Kyoko; Kusumi, Yumi; Iida, Tomohiro; Hirakata, Akito

    2015-10-01

    To report the characteristics of a macular detachment associated with peripapillary intrachoroidal cavitation (ICC) and the outcomes of vitrectomy. The medical records of 69 eyes of 61 patients who underwent vitrectomy for macular detachment or macular retinoschisis but without vitreomacular traction or optic disc pit were reviewed. Optical coherence tomography was used to determine the morphology of the ICC. The outcomes of vitrectomy including the creation of a posterior vitreous detachment and internal limiting membrane peeling were evaluated. An ICC was detected in 3 of 3 eyes without pathologic myopia but none in 66 eyes with pathologic myopia (P detachment in all eyes. Optical coherence tomography detected a connection between the vitreous cavity and the ICC in two eyes with pit-like splitting and between the subretinal space and the ICC in two eyes. The macular detachment was resolved 5 months to 6 months postoperatively with improvement of vision. A macular detachment with ICC can be present in nonpathological myopic eyes. Vitreous surgery to create a posterior vitreous detachment with internal limiting membrane peeling may help resolve the macular detachment.

  9. Retinal detachment in black South Africans | Peters | South African ...

    African Journals Online (AJOL)

    Rhegmatogenous retinal detachments seen in black patients attending King Edward VIII Hospital Ophthalmology Clinic over a 5-year period from January 1987 to December 1991 were reviewed. Penetrating trauma and diabetic retinopathy were excluded. There were 114 detachments in 112 patients, which gave incidence ...

  10. Incidence and Pattern of Retinal Detachment in a Tertiary Eye ...

    African Journals Online (AJOL)

    Objectives: The aim was to determine the hospital incidence, pattern and clinical presentation of retinal detachment at the Guinness Eye Center, Onitsha, Nigeria. Materials and Methods: Case files of all retinal detachment patients seen at the Guinness Eye Center Onitsha between June 1997 and May 2012 were reviewed.

  11. Dissociative detachment relates to psychotic symptoms and personality decompensation.

    Science.gov (United States)

    Allen, J G; Coyne, L; Console, D A

    1997-01-01

    Previous studies have addressed the prominence of psychotic symptoms in conjunction with multiple personality disorder (now dissociative identity disorder). The present study examines the relation between psychotic symptoms and a more pervasive form of dissociative disturbance, namely dissociative detachment. Two hundred sixty-six women in inpatient treatment for severe trauma-related disorders completed the Dissociative Experiences Scale (DES), and 102 of these patients also completed the Millon Clinical Multiaxial Inventory (MCMI-III). A factor analysis of the DES yielded two dimensions of dissociative detachment: detachment from one's own actions and detachment from the self and the environment. Each of these DES dimensions relates strongly to the thought disorder and schizotypal personality disorder scales of the MCMI-III. We propose that severe dissociative detachment, by virtue of loosening the moorings in inner and outer reality, is conducive to psychotic symptoms and personality decompensation.

  12. Ocular hemodynamics in patients with rhegmatogenous retinal detachment

    Directory of Open Access Journals (Sweden)

    N. H. Zavgorodnya

    2014-10-01

    Full Text Available Aim. In case of retinal detachment atrophic processes lead to irreversible loss of functions within 4–6 days, it happens on underlying low ocular blood flow. In order to evaluate the degree of violation of regional hemodynamics in patients with retinal detachment two groups of patients were examined: the main group (52 patients with rhegmatogenous retinal detachment and the control group (24 myopic patients with lattice form of peripheral chorioretinal dystrophy. Methods and results. Doppler and reography results had been compared, significant decrease of blood flow in patients with retinal detachment was found. No differences between affected and fellow eye in these patients, close negative correlation between the level of ocular blood flow and the degree of myopia in the control group. Conclusion. This demonstrates the feasibility of actions to improve regional blood flow in patients operated on for retinal detachment.

  13. Posterior vitreous detachment and retinal detachment after implantation of the Visian phakic implantable collamer lens.

    Science.gov (United States)

    Bamashmus, Mahfouth A; Al-Salahim, Seddique A; Tarish, Nabil A; Saleh, Mahmoud F; Mahmoud, Hatem A; Elanwar, Mohamed F; Awadalla, Mohamed A

    2013-01-01

    To evaluate the vitreoretinal complications in myopes after Visian implantable collamer lenses (ICL) implantation. This is a retrospective, observational, non-comparative clinical study that evaluated 617 consecutive myopes who underwent ICL implantation at the Department of Refractive Surgery, Yemen Magrabi Hospital, Sana'a, Yemen between July 2006 and May 2010. Follow up ranged from 6 months to 40 months. Preoperative and postoperative patient evaluation included manifest and cycloplegic refractions, uncorrected (UCVA) and best spectacle-corrected visual acuity (BSCVA), slit-lamp biomicroscopy, intraocular pressure and dilated retinal examination. Investigations included corneal topography, central corneal thickness, anterior chamber depth and white to white diameter. Retinal diseases and complications were recorded and analyzed preoperatively and postoperatively. Preoperatively, 61 (9.9%) eyes had posterior segment pathology requiring prophylactic laser photocoagulation. One eye developed spontaneous rhegmatogenous retinal detachment (RRD), one eye developed traumatic retinal detachment and two eyes required laser treatment postoperatively. The overall retinal detachment rate post-ICL was 0.32%. Posterior segment complications are rare after ICL implantation but dilated vitreoretinal assessment is important before and after the procedure. Patients with suspicious retinal lesions need a comprehensive vitreoretinal evaluation by a retinal specialist. If a patient develops floaters or blurry vision he/she requires further assessment by a vitreoretinal specialist.

  14. Tricuspid valve detachment in closure of congenital ventricular septal defect.

    Science.gov (United States)

    Zhao, Jinping; Li, Jun; Wei, Xiang; Zhao, Bo; Sun, Wei

    2003-01-01

    From January 1991 through December 2001, 600 patients underwent closure of a perimembranous ventricular septal defect through a right atrial approach at our institution. In 122 of these patients, the operation included temporary detachment of a tricuspid valve septal leaflet from the annulus to allow complete visualization of a perimembranous ventricular septal defect The mean age of the patients at surgery was 4.6 years in those who underwent leaflet detachment and 4.7 years in the 478 patients who did not (P > 0.05). Preoperatively, all patients were in sinus rhythm. Echocardiography showed trivial tricuspid regurgitation in 21 of the patients undergoing detachment and in 39 of the non-detachment patients. There was no difference in bypass time or aortic cross-clamp time between the 2 groups. Postoperatively, 3 patients in the non-detachment group had heart block; all other patients were in sinus rhythm. Echocardiograms on the 7th postoperative day showed small residual ventricular septal defects in none of the patients who underwent valve detachment and in 10 of the non-detachment patients; mild tricuspid regurgitation was present in 12 non-detachment patients only; and trivial tricuspid regurgitation was present in 19 patients who underwent valve detachment and in 29 who did not. There was no hospital death in either group. Long-term follow-up showed no progression of tricuspid regurgitation or tricuspid stenosis. All patients remained in sinus rhythm. This study suggests that tricuspid valve detachment is a safe, effective technique that improves exposure for ventricular septal defect repair and does not adversely affect valve competence.

  15. Pathogenesis of rhegmatogenous retinal detachment: predisposing anatomy and cell biology.

    Science.gov (United States)

    Mitry, Danny; Fleck, Brian W; Wright, Alan F; Campbell, Harry; Charteris, David G

    2010-01-01

    The pathogenesis of rhegmatogenous retinal detachment is complex, and our knowledge of the exact mechanism of vitreoretinal attachment and detachment remains incomplete. We performed a Medline, Ovid, and EMBASE search using search words rhegmatogenous, retinal detachment, vitreous, and retinal adhesion. All appropriate articles were reviewed, and the evidence was compiled. Cortical vitreous contains fibrillar collagens type II, V/XI, and IX. The inner limiting membrane of the retina contains collagens type I, IV, VI, and XVIII as well as numerous other glycoproteins and potential adhesion molecules. The distribution and age-related changes in the structure of these molecules play an important role in the formation of a retinal break, which may compromise and disrupt the normal mechanisms of neurosensory retinal adhesion. Rhegmatogenous retinal detachment development is intimately related to changes in the fibrillar structure of the aging vitreous culminating in posterior vitreous detachment with regions of persistent and tangential vitreoretinal traction predisposing to retinal tear formation. A complex interplay of factors such as weakening of vitreoretinal adhesion, posterior migration of the vitreous base, and molecular changes at the vitreoretinal interface are important in predisposing to focal areas of vitreoretinal traction precipitating rhegmatogenous retinal detachment. Once formed, the passage of liquefied vitreous through a retinal break may overwhelm normal neurosensory-retinal pigment epithelium adhesion perpetuating and extending detachment and causing visual loss. To understand the molecular events underlying rhegmatogenous retinal detachment so that new therapies can be developed, it is important to appreciate the structural organization of the vitreous, the biology underlying vitreous liquefaction and posterior vitreous detachment, and the mechanisms of vitreoretinal attachment and detachment.

  16. Advantages of diabetic tractional retinal detachment repair

    Directory of Open Access Journals (Sweden)

    Sternfeld A

    2015-10-01

    Full Text Available Amir Sternfeld, Ruth Axer-Siegel, Hadas Stiebel-Kalish, Dov Weinberger, Rita Ehrlich Department of Ophthalmology, Rabin Medical Center, Beilinson Campus, Petach Tikva, Israel Purpose: To evaluate the outcomes and complications of patients with diabetic tractional retinal detachment (TRD treated with pars plana vitrectomy (PPV.Patients and methods: We retrospectively studied a case series of 24 eyes of 21 patients at a single tertiary, university-affiliated medical center. A review was carried out on patients who underwent PPV for the management of TRD due to proliferative diabetic retinopathy from October 2011 to November 2013. Preoperative and final visual outcomes, intraoperative and postoperative complications, and medical background were evaluated.Results: A 23 G instrumentation was used in 23 eyes (95.8%, and a 25 G instrumentation in one (4.2%. Mean postoperative follow-up time was 13.3 months (4–30 months. Visual acuity significantly improved from logarithm of the minimum angle of resolution (LogMAR 1.48 to LogMAR 1.05 (P<0.05. Visual acuity improved by ≥3 lines in 75% of patients. Intraoperative complications included iatrogenic retinal breaks in seven eyes (22.9% and vitreal hemorrhage in nine eyes (37.5%. In two eyes, one sclerotomy was enlarged to 20 G (8.3%. Postoperative complications included reoperation in five eyes (20.8% due to persistent subretinal fluid (n=3, vitreous hemorrhage (n=1, and dislocated intraocular lens (n=1. Thirteen patients (54.2% had postoperative vitreous hemorrhage that cleared spontaneously, five patients (20.8% required antiglaucoma medications for increased intraocular pressure, seven patients (29.2% developed an epiretinal membrane, and two patients (8.3% developed a macular hole.Conclusion: Patients with diabetic TRD can benefit from PPV surgery. Intraoperative and postoperative complications can be attributed to the complexity of this disease. Keywords: diabetic retinopathy, proliferative

  17. Functional and anatomical remodeling in human retinal detachment.

    Science.gov (United States)

    de Souza, Clairton F; Kalloniatis, Michael; Polkinghorne, Philip J; McGhee, Charles N J; Acosta, Monica L

    2012-04-01

    Rhegmatogenous retinal detachment is by far the most common indication for retinal surgery and a major cause of severe vision loss. Increased levels of glutamate found in the vitreous of human patients and persistent remodeling, even after reattachment, suggest substantial neurochemical, functional and anatomical changes have occurred in the detached retina. Therefore, this study was designed to characterize the morphological changes and glutamate receptor functionality in human rhegmatogenous retinal detachment. A cation channel permeating probe, agmatine (1-amino-4-guanidobutane; AGB), was employed to track endogenous and kainate (KA) driven channel functionality combined with immunocytochemical characterization of cellular remodeling. In the detached retina increased AGB permeability was identified in the outer retina while there was a decrease in the inner retina in basal conditions. KA receptors exhibited increased AGB permeability in ON bipolar cells and decreased permeability in calbindin labeled inner retinal cells. All retinal detachment samples demonstrated ectopic synaptic protein expression, photoreceptor processes extending toward the inner retina, and other remodeling features of retinal degeneration. These anatomical changes have been demonstrated in animal studies and are novel features unreported in primary cases of human retinal detachment. We conclude that deafferentation in retinal detachment leads to alteration of the glutamatergic pathway. Copyright © 2012 Elsevier Ltd. All rights reserved.

  18. A computer investigation of chemically mediated detachment in bacterial biofilms.

    Science.gov (United States)

    Hunt, Stephen M; Hamilton, Martin A; Sears, John T; Harkin, Gary; Reno, Jason

    2003-05-01

    A three-dimensional computer model was used to evaluate the effect of chemically mediated detachment on biofilm development in a negligible-shear environment. The model, BacLAB, combines conventional diffusion-reaction equations for chemicals with a cellular automata algorithm to simulate bacterial growth, movement and detachment. BacLAB simulates the life cycle of a bacterial biofilm from its initial colonization of a surface to the development of a mature biofilm with cell areal densities comparable to those in the laboratory. A base model founded on well established transport equations that are easily adaptable to investigate conjectures at the biological level has been created. In this study, the conjecture of a detachment mechanism involving a bacterially produced chemical detachment factor in which high local concentrations of this detachment factor cause the bacteria to detach from the biofilm was examined. The results show that the often observed 'mushroom'-shaped structure can occur if detachment events create voids so that the remaining attached cells look like mushrooms.

  19. Ethnic variation in rhegmatogenous retinal detachments

    Science.gov (United States)

    Chandra, A; Banerjee, P; Davis, D; Charteris, D

    2015-01-01

    Purpose We aimed to investigate the clinical variation of rhegmatogenous retinal detachments (RD) in patients of different ethnicities. Methods Patients presenting with a primary RD from two ethnic groups were recruited from our tertiary referral hospital between August 2010 and December 2012. Patients who self-reported their ethnic origin either as European Caucasian (EC) or South Asian (SA) were included. Exclusion criteria included trauma, previous vitreoretinal procedures, age under 18 years, complicated cataract surgery and the presence of syndromes known to be associated with a high prevalence of RD. Detailed phenotypic data were collected. Descriptive and comparative statistical analyses were undertaken. Results 1269 Patients were recruited. 1173 (92.4%) were EC. Mean age of onset was 58.3 years (EC) and 54.5 years (SA) (P=0.006). 75.3% EC and 58.4% SA were phakic (Plattice retinal degeneration in the affected eye (P=0.003). Refractive myopia was greater in SA patients (mean: −6.1DS) than EC (−4.2DS) (P=0.032). Additionally, SA patients had a greater mean axial length (25.65 mm) than EC (25.06 mm) (P=0.014). No differences were demonstrated in laterality, family history, type of retinal break or macular status. Conclusions SA patients present with RD at an earlier age and have a more severe phenotype than ECs. Future management strategies for RD may need to reflect these differences. PMID:25853394

  20. SHARPIN Regulates Uropod Detachment in Migrating Lymphocytes

    Directory of Open Access Journals (Sweden)

    Jeroen Pouwels

    2013-11-01

    Full Text Available SHARPIN-deficient mice display a multiorgan chronic inflammatory phenotype suggestive of altered leukocyte migration. We therefore studied the role of SHARPIN in lymphocyte adhesion, polarization, and migration. We found that SHARPIN localizes to the trailing edges (uropods of both mouse and human chemokine-activated lymphocytes migrating on intercellular adhesion molecule-1 (ICAM-1, which is one of the major endothelial ligands for migrating leukocytes. SHARPIN-deficient cells adhere better to ICAM-1 and show highly elongated tails when migrating. The increased tail lifetime in SHARPIN-deficient lymphocytes decreases the migration velocity. The adhesion, migration, and uropod defects in SHARPIN-deficient lymphocytes were rescued by reintroducing SHARPIN into the cells. Mechanistically, we show that SHARPIN interacts directly with lymphocyte-function-associated antigen-1 (LFA-1, a leukocyte counterreceptor for ICAM-1, and inhibits the expression of intermediate and high-affinity forms of LFA-1. Thus, SHARPIN controls lymphocyte migration by endogenously maintaining LFA-1 inactive to allow adjustable detachment of the uropods in polarized cells.

  1. Ohmic discharges in Tore Supra - Marfes and detached plasmas

    International Nuclear Information System (INIS)

    Vallet, J.C.

    1990-01-01

    The Tore Supra plasma characteristics are given. The observed discharges are either leaning on the graphite inner first wall or limited by movable pump limiters located outboard and at the bottom of the vacuum chamber. The particular plasma conditions which lead to marfes and detached plasmas in ohmically heated He and D2 discharges limited by the inner wall are investigated. The results show that the ratio of radiated power to ohmic power increase linearly with M.g. As M.g rises, attached plasma, marfe and detached plasma are sequentially observed. Detached plasma with an effective radius as small as. 7 times the limiter radius was observed on Tore Supra

  2. Shape Evolution of Detached Bridgman Crystals Grown in Microgravity

    Science.gov (United States)

    Volz, M. P.; Mazuruk, K.

    2015-01-01

    A theory describing the shape evolution of detached Bridgman crystals in microgravity has been developed. A starting crystal of initial radius r0 will evolve to one of the following states: Stable detached gap; Attachment to the crucible wall; Meniscus collapse. Only crystals where alpha plus omega is great than 180 degrees will achieve stable detached growth in microgravity. Results of the crystal shape evolution theory are consistent with predictions of the dynamic stability of crystallization (Tatarchenko, Shaped Crystal Growth, Kluwer, 1993). Tests of transient crystal evolution are planned for ICESAGE, a series of Ge and GeSi crystal growth experiments planned to be conducted on the International Space Station (ISS).

  3. Vitrectomy, lensectomy and silicone oil tamponade in the management of retinal detachment associated with choroidal detachment

    Directory of Open Access Journals (Sweden)

    Jian-Di Liu

    2013-06-01

    Full Text Available AIM: To report the results of combined vitrectomy, lensectomy and silicone oil (SO tamponade in treating primary rhegmatogenous retinal detachment (RRD associated with choroidal detachment (CD.METHODS: A retrospective, consecutive and case series study of 21 subjects with concurrent RRD associated with CD was conducted. All subjects underwent a standard three-port 20G pars plana vitrectomy (PPV with lensectomy and silicone oil tamponade. Mean follow-up time was 8 months (rang from 4 to 19 months. The primary and final anatomic success rate, visual acuity and final intraocular pressure(IOP were recorded and analyzed.RESULTS: Of 21 subjects, 8 were women and 13 were men. Age at presentation ranged from 22 to 75 years (mean 57.4 years. The presenting vision ranged from light perception to 0.15. The initial IOP ranged from 3mmHg to 12mmHg (mean 6.2mmHg. All eyes were phakic except one pseudophakic. No intraocular lens was implanted during the primary surgical intervention. Fifteen of 21 (71.4% eyes had retina reattached after one operation. Six eyes had recurrent inferior retinal detachment due to proliferation. Five of them were successfully reattached after one or more additional operations. Mean IOP at final follow-up was 15.2mmHg (range from 8mmHg to 20mmHg. One case declined for further operation. The final reattachment rate was 95.2%. Visual acuity improved in 19 (90.5% eyes, was unchanged in 1 (4.8% eye and decreased in 1 (4.8% eye.CONCLUSION: Combination of vitrectomy, lensectomy and silicone tamponade is an effective method in treating RRD associated with CD, reducing the incidence of postoperative hypotony.

  4. The potential and need for energy saving in standard family detached and semi-detached wooden houses in arctic Greenland

    DEFF Research Database (Denmark)

    Bjarløv, Søren Peter; Vladyková, Petra

    2011-01-01

    The paper gives an account of the potential and need for energy saving in standard family detached and semi-detached wooden houses in Greenland. It is based on studies of house construction compared with Building Regulation requirements and the spread of buildings over time. In the climatic...... conditions of Greenland, there is considerable potential for energy saving in houses due to their construction, shape and condition. To estimate the total potential for energy saving and thus reducing CO2 emissions, we carried out a detailed investigation of three typical standard semi-detached family houses...

  5. Disappearance of a detached vapor mass in subcooled water

    International Nuclear Information System (INIS)

    Inada, Shigeaki; Miyasaka, Yoshiki; Izumi, Ryotaro.

    1986-01-01

    Experiments on pool transition boiling of water under atmospheric pressure on a heated surface 10 mm in diameter were conducted for subcooling 15 - 50 K. The mass flux of condensation of a detached coalescent vapor bubble was experimentally estimated by a mathematical model based on the mass transfer mechanism of condensation. As a result, it is clarified that the mass flux of condensation of the detached bubble was influenced by the initial growing velocity of a vapor bubble immediately following the detached bubble. The disappearance velocity of the detached bubble defined as a ratio of the bubble diameter at the departure to the time required until the disappearance, is in the range 0.2 to 2.0 m/sec. The disappearance velocity is proportional to the initial growing velocity of the bubble, to the square of the heat flux of the heated surface and to the cube of the wall superheat, separately. (author)

  6. Method of detaching adherent cells for flow cytometry

    KAUST Repository

    Kaur, Mandeep

    2015-12-24

    In one aspect, a method for detaching adherent cells can include adding a cell lifting solution to the media including a sample of adherent cells and incubating the sample of adherent cells with the cell lifting solution. No scraping or pipetting is needed to facilitate cell detachment. The method do not require inactivation of cell lifting solution and no washing of detaching cells is required to remove cell lifting solution. Detached cells can be stained with dye in the presence of cell lifting solution and are further analyzed using flow cytometer. The method has been tested using 6 different cell lines, 4 different assays, two different plate formats (96 and 384 well plates) and two different flow cytometry instruments. The method is simple to perform, less time consuming, with no cell loss and makes high throughput flow cytometry on adherent cells a reality.

  7. Tracing detached and attached care practices in nursing education

    DEFF Research Database (Denmark)

    Soffer, Ann Katrine B.

    2014-01-01

    of care are not explicated in the curriculum or textbooks; however, they surfaced once this crooked approach to studying care in a simulated practice was applied. The article starts from the assertion that detached engagements are not recognized within the field of nursing education as an equal component...... to attachments. Yet empirical cases from the skills lab and hospitals illustrate how students sometimes felt emotionally attached to plastic dummies and how experienced nurses sometimes practised a degree of detachment in relation to human patients. Detached engagements will therefore be presented as part......The implementation of skills labs in Danish nursing education can, in itself, be viewed as a complexity. The students are expected to eventually carry out their work in a situated hospital practice, but they learn their professional skills in a different space altogether, detached and removed from...

  8. Serous retinal detachment after trabeculectomy in angle recession glaucoma

    Directory of Open Access Journals (Sweden)

    Roy, Avik Kumar

    2015-12-01

    Full Text Available An 18-year-old male with 360 degree angle recession after blunt trauma in his right eye developed uncontrolled intraocular pressure (IOP despite four antiglaucoma medications (AGM with advancing disc damage. He underwent trabeculectomy with intraoperative mitomycin-c (MMC application. There was an intraoperative vitreous prolapse which was managed accordingly. On post-surgery day 1, he had shallow choroidal detachment superiorly with non-recordable IOP. This was deteriorated 1 week postoperatively as choroidal detachment proceeded to serous retinal detachment. He was started with systemic steroid in addition to topical route. The serous effusions subsided within 2 weeks time. At the last follow up at 3 months, he was enjoying good visual acuity, deep anterior chamber, diffuse bleb, an IOP in low teens off any AGM and attached retina. This case highlights the rare occurrence of serous retinal detachment after surgical management of angle recession glaucoma.

  9. Fluid–rock interaction across the South Tibetan Detachment ...

    Indian Academy of Sciences (India)

    scale normal fault system called the South Tibetan Detachment (STD). A mineralogical, geochemical and fluid inclusion study of samples from the fault zone of the Malari Granite was performed to reveal the imprints of fluid–rock interaction.

  10. Scleral buckling for retinal detachment in patients with retinoblastoma

    International Nuclear Information System (INIS)

    Buzney, S.M.; Pruett, R.C.; Regan, C.D.; Walton, D.S.; Smith, T.R.

    1984-01-01

    Three children (two girls and one boy) with bilateral retinoblastoma each developed a presumed rhegmatogenous retinal detachment in one eye. All three eyes had previously received radiation and cryotherapy. In each case the retinal detachment responded promptly to conventional surgical methods via scleral buckling in the area of treated retinoblastoma and presumed retinal break. All three eyes have retained useful vision for follow-up periods of 3.5 to 12 years

  11. Scleral buckling for retinal detachment in patients with retinoblastoma

    Energy Technology Data Exchange (ETDEWEB)

    Buzney, S.M.; Pruett, R.C.; Regan, C.D.; Walton, D.S.; Smith, T.R.

    1984-10-15

    Three children (two girls and one boy) with bilateral retinoblastoma each developed a presumed rhegmatogenous retinal detachment in one eye. All three eyes had previously received radiation and cryotherapy. In each case the retinal detachment responded promptly to conventional surgical methods via scleral buckling in the area of treated retinoblastoma and presumed retinal break. All three eyes have retained useful vision for follow-up periods of 3.5 to 12 years.

  12. Retinal Detachment due to CrossFit Training Injury

    Directory of Open Access Journals (Sweden)

    Stephanie A. Joondeph

    2013-01-01

    Full Text Available The purpose of this paper is to describe a traumatic retinal detachment occurring as a result of CrossFit training using an elastic exercise band. The patient sustained an ocular injury from an elastic band during CrossFit training, resulting in a giant retinal dialysis and retinal detachment, which were successfully repaired. Trainers and athletes need to be aware of the potential for ocular injury from elastic exercise bands and take appropriate precautions.

  13. Retinal Detachment due to CrossFit Training Injury.

    Science.gov (United States)

    Joondeph, Stephanie A; Joondeph, Brian C

    2013-01-01

    The purpose of this paper is to describe a traumatic retinal detachment occurring as a result of CrossFit training using an elastic exercise band. The patient sustained an ocular injury from an elastic band during CrossFit training, resulting in a giant retinal dialysis and retinal detachment, which were successfully repaired. Trainers and athletes need to be aware of the potential for ocular injury from elastic exercise bands and take appropriate precautions.

  14. Retinal Detachment due to CrossFit Training Injury

    OpenAIRE

    Joondeph, Stephanie A.; Joondeph, Brian C.

    2013-01-01

    The purpose of this paper is to describe a traumatic retinal detachment occurring as a result of CrossFit training using an elastic exercise band. The patient sustained an ocular injury from an elastic band during CrossFit training, resulting in a giant retinal dialysis and retinal detachment, which were successfully repaired. Trainers and athletes need to be aware of the potential for ocular injury from elastic exercise bands and take appropriate precautions.

  15. An analysis of the mechanical behaviour of a detaching retina.

    Science.gov (United States)

    Lakawicz, Joseph M; Bottega, William J; Prenner, Jonathan L; Fine, Howard F

    2015-06-01

    An improved solution to the mechanics-based mathematical model for retinal detachment developed by Bottega et al. (2013, Math. Med. Biol., 30, 287-310) is found by removing the simplifying assumption of negligible meridian displacement employed in that study. The model considers retinas with and without central tears and takes contraction of the vitreous and extension of its fibrils, along with a pressure difference across the retina, as the impetus for detachment propagation. Exact analytical solutions are established for the meridian and radial displacements of detaching retinas with and without tears, and numerical simulations are performed based on these solutions. Inclusion of the meridian displacements is seen to result in substantially larger radial displacements without affecting the 'dimpling' behaviour of the detaching retina observed previously. However, the critical stress for detachment propagation is substantially decreased by the inclusion of the meridian displacement. The effects of changes in material and geometric parameters, as well as the influence of the presence and size of the retinal tear on detachment propagation are also studied. The model predicts that retinal detachment propagates catastrophically, which is in agreement with the results found by Bottega et al. (2013, Math. Med. Biol., 30, 287-310) and also with clinical observations. Results show that the inclusion of the meridian displacements enhances the previously seen stabilizing effect a retinal tear can have with regard to detachment propagation. The meridian displacement is similarly seen to enhance the influence that the size of the tear has on this effect. © The Authors 2014. Published by Oxford University Press on behalf of the Institute of Mathematics and its Applications. All rights reserved.

  16. An Unusual Case of Extensive Lattice Degeneration and Retinal Detachment

    OpenAIRE

    Mathew, David J.; Sarma, Saurabh Kumar; Basaiawmoit, Jennifer V.

    2016-01-01

    Lattice degeneration of the retina is not infrequently encountered on a dilated retinal examination and many of them do not need any intervention. We report a case of atypical lattice degeneration variant with peripheral retinal detachment. An asymptomatic 35-year-old lady with minimal refractive error was found to have extensive lattice degeneration, peripheral retinal detachment and fibrotic changes peripherally with elevation of retinal vessels on dilated retinal examination. There were al...

  17. [Prevention of retinal detachment and treatment of retinoschisis].

    Science.gov (United States)

    Messmer, E P

    1990-01-01

    The necessity for prophylactic treatment for degenerative disease in the peripheral retina cannot be evaluated merely on the basis of the ophthalmoscopic findings. Factors such as the patient's history, refraction, the status of the vitreous, and prospective future cataract extraction all have a major impact on the risk of developing retinal detachment. The latter condition can be classified in to three groups: (1) low risk (patients with no history of retinal detachment, intraocular surgery or posterior vitreous detachment, myopia less than three diopters): treatment of atrophic holes and lattice degeneration is not justified, treatment of flap tears according to the circumstances; (2) medium risk (patients with no history of retinal or posterior vitreous detachment; however, myopia of more than three diopters and/or aphakia): the treatment of lattice degeneration is not justified; treatment of breaks according to the circumstances; (3) high risk: (patients with symptoms of posterior vitreous detachment): the treatment of lattice degeneration and atrophic holes is not justified: treatment of tears is necessary; fellow eyes: the treatment of retinal breaks is necessary; treatment of lattice degeneration seems advisable in cases with bilateral symmetric findings or prior to cataract extraction. Treatment of senile retinoschisis is only justified in cases with large and centrally located holes in the outer wall or in the presence of symptomatic schisis detachment.

  18. The fellow eye of patients with phakic rhegmatogenous retinal detachment from atrophic holes of lattice degeneration without posterior vitreous detachment.

    Science.gov (United States)

    Gonzales, C R; Gupta, A; Schwartz, S D; Kreiger, A E

    2004-11-01

    Primary phakic rhegmatogenous retinal detachment (RRD) without posterior vitreous detachment (PVD) represents a unique clinical entity that behaves differently from RRD associated with PVD. While previous studies have reported the long term findings in the fellow eye of patients with RRD and PVD, the outcome of the fellow eye of patients with RRD without PVD is not known. Consecutive patients with RRD not associated with PVD were studied retrospectively. The authors evaluated the fellow eye for retinal detachment or other vision threatening pathology. 27 patients (mean age 32 years) were studied with follow up of between 9 and 326 months (mean 111 months). 24 (89%) were myopic. Bilateral retinal detachment occurred in eight patients (30%). On initial examination, 17 patients (63%) had retinal findings (including lattice degeneration, atrophic holes, and/or cystic retinal tufts) in the fellow eye that might predispose them to retinal detachment. 14 vision threatening events or diagnoses occurred (nine of which were rhegmatogenous in nature) in the fellow eye including eight retinal detachments, one traumatic PVD without retinal tears, one retinal tear after PVD, one diagnosis of pigmentary glaucoma needing trabeculectomy, two visually significant cataracts, and one diagnosis of chorioretinitis. 23 patients (85%) maintained visual acuity better than 20/50, with most retaining 20/20 vision in the fellow eye. Patients who experience RRD without PVD are at risk of developing vision threatening events in the contralateral eye and, as such, the fellow eye should be followed carefully.

  19. A Chick Model of Retinal Detachment: Cone Rich and Novel

    Science.gov (United States)

    Cebulla, Colleen M.; Zelinka, Chris P.; Scott, Melissa A.; Lubow, Martin; Bingham, Amanda; Rasiah, Stephen; Mahmoud, Ashraf M.; Fischer, Andy J.

    2012-01-01

    Background Development of retinal detachment models in small animals can be difficult and expensive. Here we create and characterize a novel, cone-rich retinal detachment (RD) model in the chick. Methodology/Principal Findings Retinal detachments were created in chicks between postnatal days 7 and 21 by subretinal injections of either saline (SA) or hyaluronic acid (HA). Injections were performed through a dilated pupil with observation via surgical microscope, using the fellow eye as a control. Immunohistochemical analyses were performed at days 1, 3, 7, 10 and 14 after retinal detachment to evaluate the cellular responses of photoreceptors, Müller glia, microglia and nonastrocytic inner retinal glia (NIRG). Cell proliferation was detected with bromodeoxyuridine (BrdU)-incorporation and by the expression of proliferating cell nuclear antigen (PCNA). Cell death was detected with terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL). As in mammalian models of RD, there is shortening of photoreceptor outer segments and mis-trafficking of photoreceptor opsins in areas of RD. Photoreceptor cell death was maximal 1 day after RD, but continued until 14 days after RD. Müller glia up-regulated glial fibriliary acidic protein (GFAP), proliferated, showed interkinetic nuclear migration, and migrated to the subretinal space in areas of detachment. Microglia became reactive; they up-regulated CD45, acquired amoeboid morphology, and migrated toward outer retina in areas of RD. Reactive NIRG cells accumulated in detached areas. Conclusions/Significance Subretinal injections of SA or HA in the chick eye successfully produced retinal detachments and cellular responses similar to those seen in standard mammalian models. Given the relatively large eye size, and considering the low cost, the chick model of RD offers advantages for high-throughput studies. PMID:22970190

  20. Cost-Utility of Evaluation for Posterior Vitreous Detachment and Prophylaxis of Retinal Detachment.

    Science.gov (United States)

    Yannuzzi, Nicolas A; Chang, Jonathan S; Brown, Gary C; Smiddy, William E

    2018-01-01

    To evaluate the costs and cost-utility of examination for posterior vitreous detachment (PVD) and treatment of associated pathology, and of managing various other peripheral retinal disorders to prevent retinal detachment (RD). A decision analysis model of cost-utility. There were no participants. Published retrospective data on the natural course of PVD, retinal tears, and lattice degeneration were used to quantitate the visual benefits of examination and treatment. Center for Medicare and Medicaid Services data were used to calculate associated modeled costs in a hospital/facility-based and nonfacility/ambulatory surgical center (ASC)-based setting. Published standards of utility for a given level of visual acuity were used to derive costs and quality-adjusted life years (QALYs). Cost of evaluation and treatment, utility of defined health states, QALY, and cost per QALY. The modeled cost of evaluation of a patient with PVD and treatment of associated pathology in the facility/hospital (nonfacility/ASC)-based setting was $65 to $190 ($25-$71) depending on whether a single or 2-examination protocol was used. The cost per QALY saved was $255 to $638/QALY ($100-$239/QALY). Treatment of a symptomatic horseshoe tear resulted in a net cost savings of $1749 ($1314) and improved utility, whereas treatment of an asymptomatic horseshoe tear resulted in $2981/QALY ($1436/QALY). Treatment of asymptomatic lattice degeneration in an eye in which the fellow eye had a history of RD resulted in $4414/QALY ($2187/QALY). Evaluation and management of incident acute PVD (and symptomatic horseshoe tears) offer a low cost and a favorable cost-utility (low $/QALY) as a result of the minimization of the cost and morbidity associated with the development of RD, thus justifying current practice standards. Copyright © 2017 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  1. Self-sustained detachment observed in LHD and comparison with detachment and Marfe in W7-AS

    Energy Technology Data Exchange (ETDEWEB)

    Miyazawa, J.; Masuzaki, S.; Yamada, H.; Sakamoto, R.; Peterson, B. J.; Shoji, M.; Ohyabu, N.; Komori, A.; Motojima, O.

    2005-07-01

    One of the crucial issues for a magnetically confined fusion reactor [1-3] is the reduction of the divertor heat load. Edge plasma cooling by increasing the density or introducing impurities such as neon as radiators is effective for reducing the divertor heat load by detaching the plasma from the divertor plates. In high-density tokamak plasmas, the so-called high-recycling regime is predicted by two-point model [4,5], where the divertor temperature (density) nonlinearly decreases (increases) with the main plasma density. Detachment takes place when the density is increased further. Then, the pressure in the flux tube is no longer conserved due to the increased radiation loss, charge exchange loss, and volume recombination. Eventually, the discharge is terminated by disruption often via rapid formation of a radiation condensation Marfe [5,6]. This scenario well explains the experimental results of tokamaks [5,7]. A similar kind of conventional detachment has been also intensively studied in a stellarator, W7-AS, after modification to the island divertor configuration [8,9]. Detachment in W7-AS is achieved by increasing the density beyond the density threshold for the high-density H-mode (HDH) [10]. As the density is increased further to the operational density limit, complete detachment takes place and, in some cases, the Marfe is formed on (or inside of) the last-closed-flux-surface (LCFS) [11-13]. These are reviewed in Section 4. Recently, a new state of self-sustained detachment has been found in LHD and named the Serpens mode (Self-regulated plasma edge neath the last-closed-flux-surface) [15,16]. In the Serpens mode, the hot plasma boundary is shrinking to equal 90 % of the LCFS radius. Large fluctuations appear in the divertor flux, H alpha and Cm signals, together with a rotating radiation belt named the serpent [17]. Detachment in LHD is observed in a significant decrease in the ion saturation current, Isat, measured on the divertor tiles [18,19]. In this

  2. A review of direct experimental measurements of detachment

    Science.gov (United States)

    Boedo, J.; McLean, A. G.; Rudakov, D. L.; Watkins, J. G.

    2018-04-01

    Detached divertor plasmas feature strong radial and parallel gradients of density, temperature, electric fields and flow over the divertor volume and therefore, sampling the divertor plasma directly provides crucial knowledge to the interpretation and modeling efforts. We review the contribution of diagnostics that directly sample the plasma to the advancement of knowledge of the physics of detachment and detached divertors, such as the characteristics of the various regimes, discovery and quantification of drifts and identification of convection of heat and particles. We focus on wall probes, scanning probes, retarding field analyzers and Thomson scattering in the divertor region and also include the contribution of measurements away from the divertor that provide insight on how divertor detachment affects core, edge or pedestal conditions. Wall probes are critical as they can be installed in closed volumes of difficult access to other diagnostics and measure plasma parameters at the divertor structures, which define the plasma boundary conditions and where detachment effects are more likely to be strongest.

  3. Adhesion and detachment of a capsule in axisymmetric flow

    Science.gov (United States)

    Keh, M. P.; Leal, L. G.

    2016-05-01

    The adhesion and detachment of a capsule on a solid boundary surface is studied via a combination of scaling theory and numerical simulation and the behavior is compared and contrasted with a vesicle. It is shown that the dominant physical property for both capsules and vesicles is the area dilation modulus Ks of the membrane. The nonzero shear modulus Gs for capsules increases the resistance to deformation and thus decreases slightly the equilibrium contact radius for an adhered capsule compared to an adhered vesicle. The detachment process in this study is due to an external axisymmetric flow. Unlike a rigid body that must be pulled away without change of shape, capsules (and vesicles) almost always detach dominantly by peeling in which the contact radius decreases but the minimum separation distance does not change until the final moments of detachment. Compared to a vesicle with the same Ks, a capsule maintains a more compact shape and is harder to elongate under a given external flow. Hence, the detachment process is slower for capsules compared to vesicles with the same Ks.

  4. Miocene detachment faulting predating EPR propagation: Southern Baja California

    Science.gov (United States)

    Bot, Anna; Geoffroy, Laurent; Authemayou, Christine; Bellon, Hervé; Graindorge, David; Pik, Raphaël.

    2016-05-01

    At the southern tip of the Baja California peninsula, we characterize the onshore structures and kinematics associated with crustal necking leading up to the Pliocene breakup and early East Pacific Rise seafloor spreading. From a combination of tectonic field investigations, K-Ar and cosmogenic isotope dating and geomorphology, we propose that the Los Cabos block represents the exhumed footwall of a major detachment fault. This north trending detachment fault is marked by a conspicuous low-dipping brittle-ductile shear zone showing a finite displacement with top to the SE ending to the ESE. This major feature is associated with fluid circulations which led to rejuvenation of the deformed Cretaceous magmatic rocks at a maximum of 17.5 Ma. The detachment footwall displays kilometer-scale corrugations controlling the present-day drainage pattern. This major detachment is synchronous with the development of the San José del Cabo Basin where syntectonic sedimentation took place from the middle Miocene to probably the early Pliocene. We propose that this seaward dipping detachment fault accommodates the proximal crustal necking of the Baja California passive margin, which predates the onset of formation of the East Pacific Rise spreading axis in the Cabo-Puerto Vallarta segment. Our data illustrate an apparent anticlockwise rotation of the stretching direction in Baja California Sur from ~17 Ma to the Pliocene.

  5. Surgical and Visual Outcome for Recurrent Retinal Detachment Surgery

    Directory of Open Access Journals (Sweden)

    Constantin Pournaras

    2014-01-01

    Full Text Available Purpose. To evaluate the anatomical and functional outcome of repeated surgeries for recurrent retinal detachment. Methods. We retrospectively reviewed 70 cases with refractory retinal detachment of various etiologies that required multiple operations. Anatomical success (attached retina or failure (totally/partially-detached retina was assessed biomicroscopically. The BCVA was used for the evaluation of the functional outcome, at presentation and at the end of follow-up. Various pre-, intra-, and postoperative factors were associated with anatomical success or failure as well as with final functionality. Results. The mean number of surgeries was 4 (range: 2 to 10. The anatomical success rate was 80% (56 attached cases, 14 detached cases. 29% of the attached cases had a BCVA better than 20/40 (Snellen chart. The number of operations doesn’t seem to affect significantly the final visual acuity. The PVR was found to affect both the anatomical and functional outcome (P=0.014 & P=0.002, respectively. Conclusions. In the present study, it is suggested that multiple operations for refractory retinal detachment may result in successful anatomic results, with a fare functional outcome at the same time. Eventually, we verified that the existence of PVR worsens the prognosis.

  6. Lattice degeneration of the retina and retinal detachment.

    Science.gov (United States)

    Semes, L P

    1992-01-01

    Lattice retinal degeneration is considered the most significant peripheral retinal disorder potentially predisposing to retinal breaks and retinal detachment. Lattice degeneration affects the vitreous and inner retinal layers with secondary changes as deep as the retinal pigment epithelium and perhaps the choriocapillaris. Variations in clinical appearance are the rule; geographically, lattice lesions favor the vertical meridians between the equator and the ora serrata. Lattice degeneration begins early in life and has been reported in sequential generations of the same family. Along with its customary bilateral occurrence, lattice shares other characteristics of a dystrophy. The association between the vitreous and retina in lattice lesions may be responsible for the majority of lattice-induced retinal detachments. The tumultuous event of posterior vitreous separation in the presence of abnormally strong vitreoretinal adherence is the trigger for a retinal tear that, in turn, may lead to retinal detachment. Although retinal holes in young patients with lattice degeneration may play a role in the evolution of retinal detachment, the clinical course of lattice degeneration seems to be one of dormancy rather than of progressive change. This discussion outlines the pathophysiology of lattice retinal degeneration and the relationship of pathophysiology to clinical presentation. The epidemiology of lattice degeneration is summarized, as are the possible precursors to retinal detachment. A clinical characterization of the natural history of lattice degeneration is offered, and interventions for complications are described. To conclude, management strategies from a primary-care standpoint are reviewed.

  7. [Preventive treatment of retinal detachment in aphakic eyes].

    Science.gov (United States)

    Regnault, F; Bregeat, P

    1977-01-01

    We have examined 243 cases with retinal detachment occurring within 6 months following cataract surgery. In 92 of them retinal tear was due to lattice degeneration, in 66 to snail track degeneration and in 17 to equatorial degeneration. 290 other patients had preventive treatments. In this group, there were only 10 cases of retinal detachment. 9 out of 22 patients who had no preventive treatment suffered retinal detachments. There are two reasons for the occurrence of this retinal detachment in the 6 months following cataract surgery in eyes where retinal degenerations are found: (1) surgical trauma even with cryoextraction is responsible for traction of the vitreous base, (2) rapid disappearance of the hyaluronic acid in the aphakic vitreous is responsible for the degradation of the vitreous with formation of large zones of liquid vitreous. When adhesion between the vitreous and the retinal degeneration area remains, the traction is responsible for retinal tear or retinal detachment. The importance of the preventive treatment of retinal lesions prior to cataract surgery should be stressed.

  8. The fellow eye of patients with phakic lattice retinal detachment.

    Science.gov (United States)

    Folk, J C; Arrindell, E L; Klugman, M R

    1989-01-01

    A retrospective study was performed to determine whether the prophylactic treatment of areas of lattice degeneration, holes, or breaks reduced the risk of subsequent new breaks or detachment in the fellow undetached phakic eyes of patients with a phakic lattice retinal detachment (RD). Three hundred eighty-eight consecutive patients who presented to the University of Iowa between 1959 and 1984 were followed for a mean of 7.9 +/- 5.8 years after the detachment in the first eye. Fellow eyes which received no prophylactic treatment had a 2.5 times greater risk of a new break or RD over 7 years than eyes receiving full prophylactic treatment (19.4 versus 7.5%; P = 0.0002). Fellow eyes receiving no treatment also had a greater risk of a new RD over 7 years than eyes receiving full treatment (5.1 versus 1.8%; P = 0.0125). These results do not allow us to make recommendations concerning which fellow eyes, if any, should be prophylactically treated. On the one hand, prophylactic treatment did significantly reduce the risk of new breaks and detachments. On the other hand, however, prophylactic treatment reduced the risk of new RD alone in the fellow eye only from 5.1 to 1.8% over 7 years. In addition, prophylactic treatment did not reduce the risk of detachment in the higher risk eyes with high myopia or extensive lattice.

  9. The Effects of Transient Retinal Detachment on Cavity Size and Glial and Neural Remodeling in a Mouse Model of X-Linked Retinoschisis

    Science.gov (United States)

    Luna, Gabriel; Kjellstrom, Sten; Verardo, Mark R.; Lewis, Geoffrey P.; Byun, Jiyun; Sieving, Paul A.; Fisher, Steven K.

    2009-01-01

    Purpose To determine the cellular consequences of retinal detachment in retinoschisin knockout (Rs1-KO) mice, a model for retinoschisin in humans. Methods Experimental retinal detachments (RDs) were induced in the right eyes of both Rs1-KO and wild-type (wt) control mice. Immunocytochemistry was performed on retinal tissue at 1, 7, or 28 days after RD with antibodies to anti-GFAP, -neurofilament, and -rod opsin to examine cellular changes after detachment. Images of the immunostained tissue were captured by laser scanning confocal microscopy. Quantitative analysis was performed to measure the number of Hoechst-stained photoreceptor nuclei and their density, number, and size of inner retinal cavities, as well as the number of subretinal glial scars. Results Since detachments were created with balanced salt solution, by examination, all retinas had spontaneously reattached by 1 day. Cellular responses common to many photoreceptor degenerations occurred in the nondetached retinas of Rs1-KO mice, and, of importance, RD did not appear to significantly accentuate these responses. The number of schisis cavities was not changed after detachment, but their size was reduced. Conclusions These data indicate that large short-term RD in Rs1-KO mice, followed by a period of reattachment may cause a slight increase in photoreceptor cell death, but detachments do not accentuate the gliosis and neurite sprouting already present and may in fact reduce the size of existing retinal cavities. This finding suggests that performing subretinal injections to deliver therapeutic agents may be a viable option in the treatment of patients with retinoschisis without causing significant cellular damage to the retina. PMID:19387072

  10. Metabolism during ECM Detachment: Achilles Heel of Cancer Cells?

    Science.gov (United States)

    Mason, Joshua A; Hagel, Kimberly R; Hawk, Mark A; Schafer, Zachary T

    2017-07-01

    Integrin-mediated attachment to the extracellular matrix (ECM) is required to combat the induction of programmed cell death in a variety of distinct cell types. If cells fail to maintain proper ECM attachment, they become subject to elimination via an apoptotic cell death program known as anoikis. However, anoikis inhibition is not sufficient to promote the long-term survival of ECM-detached cells. Several recent studies have unveiled the profound (anoikis-independent) impact of cell metabolism on the viability of ECM-detached cells. Thus, we posit that, during metastatic dissemination (when cancer cells are exposed to periods of ECM detachment), cancer cells must alter their metabolism in a fashion that promotes survival and ultimately contributes to metastatic outgrowth. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Simulation of experimentally achieved detached plasmas using the UEDGE code

    International Nuclear Information System (INIS)

    Porter, G.D.; Allen, S.; Fenstermacher, M.

    1995-01-01

    The introduction of a divertor Thomson scattering system in DIII-D has enabled accurate determination of the plasma properties in the divertor region. We identify two plasma regimes; detached and attached. The electron temperature in the detached regime is about 2 eV, much lower than 5 to 10 eV determined earlier. We show that fluid models of the DIII-D scrape-off layer plasma are able to reproduce many of the features of these two plasma regimes, including the boundaries for transition between them. Detailed comparison between the results obtained from the fluid models and experiment suggest the models underestimate the spatial extent of the low temperature region associated the detached plasma mode. We suggest that atomic physics processes at the low electron temperatures reported here may account for this discrepancy

  12. [Retinal pneumopexy in the treatment of rhegmatogenous retinal detachment].

    Science.gov (United States)

    Levai, L; Gavriş, Monica; Gábor, Radó; Bagosi, P

    2014-01-01

    To evaluate the efficiency of retinal pneumopexy in patients with rhegmatogenous retinal detachment. This clinical prospective study unrolled between november 2010-june 2012 in the Ophthalmology Department of the Military Hospital in Cluj-Napoca and Satu Mare Emergency Hospital included 20 patients (20 eyes) with rhegmatogenous retinal detachment. Patients were treated with retinal pneumopexy followed by laser photocoagulation. Anatomical and functional results were evaluated 1, 3, 6, 12 and 19 months after treatment. In 17 eyes out of 20, we achieved retinal reattachment and visual recovery. Three cases yelded no success, these being further treated with posterior vitrectomy. Retinal pneumopexy is a minimally invasive treatment method of rhegmatogenous retinal detachment with very good results in well selected cases.

  13. An Unusual Case of Extensive Lattice Degeneration and Retinal Detachment.

    Science.gov (United States)

    Mathew, David J; Sarma, Saurabh Kumar; Basaiawmoit, Jennifer V

    2016-07-01

    Lattice degeneration of the retina is not infrequently encountered on a dilated retinal examination and many of them do not need any intervention. We report a case of atypical lattice degeneration variant with peripheral retinal detachment. An asymptomatic 35-year-old lady with minimal refractive error was found to have extensive lattice degeneration, peripheral retinal detachment and fibrotic changes peripherally with elevation of retinal vessels on dilated retinal examination. There were also areas of white without pressure, chorioretinal scarring and retinal breaks. All the changes were limited to beyond the equator but were found to span 360 degrees. She was treated with barrage laser all around to prevent extension of the retinal detachment posteriorly. She remained stable till her latest follow-up two years after the barrage laser. This case is reported for its rarity with a discussion of the probable differential diagnoses. To the best of our knowledge, this is the first report of such findings in lattice degeneration.

  14. Peripheral retinal degenerations and the risk of retinal detachment.

    Science.gov (United States)

    Lewis, Hilel

    2003-07-01

    To review the degenerative diseases of the peripheral retina in relationship with the risk to develop a rhegmatogenous retinal detachment and to present recommendations for use in eyes at increased risk of developing a retinal detachment. Focused literature review and author's clinical experience. Retinal degenerations are common lesions involving the peripheral retina, and most of them are clinically insignificant. Lattice degeneration, degenerative retinoschisis, cystic retinal tufts, and, rarely, zonular traction tufts, can result in a rhegmatogenous retinal detachment. Therefore, these lesions have been considered for prophylactic therapy; however, adequate studies have not been performed to date. Well-designed, prospective, randomized clinical studies are necessary to determine the benefit-risk ratio of prophylactic treatment. In the meantime, the evidence available suggests that most of the peripheral retinal degenerations should not be treated except in rare, high-risk situations.

  15. Detached Solidification of Germanium-Silicon Crystals on the ISS

    Science.gov (United States)

    Volz, M. P.; Mazuruk, K.; Croell, A.

    2016-01-01

    A series of Ge(sub 1-x) Si(sub x) crystal growth experiments are planned to be conducted in the Low Gradient Furnace (LGF) onboard the International Space Station. The primary objective of the research is to determine the influence of containment on the processing-induced defects and impurity incorporation in germanium-silicon alloy crystals. A comparison will be made between crystals grown by the normal and "detached" Bridgman methods and the ground-based float zone technique. Crystals grown without being in contact with a container have superior quality to otherwise similar crystals grown in direct contact with a container, especially with respect to impurity incorporation, formation of dislocations, and residual stress in crystals. "Detached" or "dewetted" Bridgman growth is similar to regular Bridgman growth in that most of the melt is in contact with the crucible wall, but the crystal is separated from the wall by a small gap, typically of the order of 10-100 microns. Long duration reduced gravity is essential to test the proposed theory of detached growth. Detached growth requires the establishment of a meniscus between the crystal and the ampoule wall. The existence of this meniscus depends on the ratio of the strength of gravity to capillary forces. On Earth, this ratio is large and stable detached growth can only be obtained over limited conditions. Crystals grown detached on the ground exhibited superior structural quality as evidenced by measurements of etch pit density, synchrotron white beam X-ray topography and double axis X-ray diffraction.

  16. The behaviour of salt and salt caverns

    NARCIS (Netherlands)

    Fokker, P.A.

    1995-01-01

    Salts are mined for both storage and extraction purposes, either via dry or solution mining techniques. For operational, environmental and geological purposes, it is important to understand and predict the in situ behaviour of salt, in particular the creep and strength characteristics. A

  17. Magnetic Detachment and Plume Control in Escaping Magnetized Plasma

    International Nuclear Information System (INIS)

    Schmit, P.F.; Fisch, N.J.

    2008-01-01

    The model of two-fluid, axisymmetric, ambipolar magnetized plasma detachment from thruster guide fields is extended to include plasmas with non-zero injection angular velocity profiles. Certain plasma injection angular velocity profiles are shown to narrow the plasma plume, thereby increasing exhaust efficiency. As an example, we consider a magnetic guide field arising from a simple current ring and demonstrate plasma injection schemes that more than double the fraction of useful exhaust aperture area, more than halve the exhaust plume angle, and enhance magnetized plasma detachment

  18. Influence of detachment mechanisms on competition in biofilms

    DEFF Research Database (Denmark)

    Morgenroth, Eberhard Friedrich; Wilderer, P. A.

    2000-01-01

    Organism distribution in and morphology of bio®lms are determined by supply of substrate and oxygen and by detachment mechanisms. Based on mathematical simulations, competition of autotrophic and heterotrophic biomass in a bio®lm is discussed for three cases: (1) constant bio®lm thickness, (2...... autotrophic biomass in situations with long intervals between detachment with resulting high variations of the bio®lm thickness. It is concluded that the application of results from mathematical models assuming a constant bio®lm thickness may be misleading when predicting the performance of systems with large...

  19. Bilateral Simultaneous Rhegmatogenous Retinal Detachment following Laser in situ Keratomileusis

    Directory of Open Access Journals (Sweden)

    Erhan Yumusak

    2016-06-01

    Full Text Available A 21-year-old woman developed simultaneous rhegmatogenous retinal detachment after laser in situ keratomileusis (LASIK in both eyes. She underwent pars plana vitrectomy surgery combined with endolaser photocoagulation and silicone oil tamponade in the right eye. A week later, pneumatic retinopexy was done in the left eye. As the retinal tear did not seal, 360° scleral buckling surgery was performed and retina was attached. Bilateral simultaneous rhegmatogenous retinal detachment after LASIK for correction of myopia can be a serious complication. Patients should be informed about the possibility of this complication.

  20. Retinal detachment secondary to ocular perforation during retrobulbar Anaesthesia

    Directory of Open Access Journals (Sweden)

    Gopal Lingam

    1995-01-01

    Full Text Available The clinical characteristics and the retinal breaks associated with rhegmatogenous retinal detachments secondary to accidental globe perforation during local infiltration anaesthesia in five highly myopic eyes are presented. Retinal detachment was total with variable proliferative vitreoretinopathy. The pattern of retinal breaks was rather typical and predictable. Management involved vitreous surgery with internal tamponade by silicone oil in four eyes and perfluoropropane gas in one eye. At the last follow-up, all eyes had attached retina. One eye did not recover useful vision due to possible concurrent optic nerve damage.

  1. Effect of Low Salt Diet on Insulin Resistance in Salt Sensitive versus Salt Resistant Hypertension

    OpenAIRE

    Garg, Rajesh; Sun, Bei; Williams, Jonathan

    2014-01-01

    Accumulating evidence shows an increase in insulin resistance on salt restriction. We compared the effect of low salt diet on insulin resistance in salt sensitive versus salt resistant hypertensive subjects. We also evaluated the relationship between salt sensitivity of blood pressure and salt sensitivity of insulin resistance in a multivariate regression model. Studies were conducted after one week of high salt (200 mmol/day Na) and one week of low salt (10 mmol/day Na) diet. Salt sensitivit...

  2. Low-salt diet

    Science.gov (United States)

    Low-sodium diet; Salt restriction ... control many functions. Too much sodium in your diet can be bad for you. For most people, ... you limit salt. Try to eat a balanced diet. Buy fresh vegetables and fruits whenever possible. They ...

  3. Vitrectomy combined with periocular/intravitreal injection of steroids for rhegmatogenous retinal detachment associated with choroidal detachment.

    Science.gov (United States)

    Wei, Yong; Wang, Ningli; Chen, Fenghua; Wang, Huaizhou; Bi, Chuncao; Zu, Zhongqiao; Yang, Xingguang

    2014-01-01

    To study the anatomical outcome of rhegmatogenous retinal detachment combined with choroidal detachment after pars plana vitrectomy with periocular/intravitreal injection of steroids. Seventy-seven eyes that have rhegmatogenous retinal detachment combined with choroidal detachment were treated by pars plana vitrectomy with oral prednisolone (Group A) or periocular/intravitreal injection of steroids (Group B) and then divided into 5 subgroups according to different intraocular tamponade agents; Group A1: oral steroids and silicone oil, Group A2: oral steroids and C(3)F(8), Group B1: periocular/intravitreal steroid injections and silicone oil, Group B2: periocular steroid injection and silicone oil, and Group B3: periocular steroid injection and C(3)F(8). Anatomical reattachment of the retina was measured at 12 months after surgery. There was no significant difference in retinal reattachment rate between eyes in Group A and eyes in Group B (77.4% vs. 73.9%, P = 0.726). The retinal reattachment rates were 83.3% in Group A1, 69.2% in Group A2, 82.4% in Group B1, 73.3% in Group B2, and 64.3% in Group B3. There was no statistical difference in the retinal reattachment rates between any of the groups. For the treatment of rhegmatogenous retinal detachment combined with choroidal detachment, pars plana vitrectomy with periocular/intravitreal corticosteroids was comparable in reattachment rate to pars plana vitrectomy with systemic steroids, suggesting an acceptable alternative for patients with this condition who cannot tolerate systemic steroids.

  4. 21 CFR 100.155 - Salt and iodized salt.

    Science.gov (United States)

    2010-04-01

    ... FOR HUMAN CONSUMPTION GENERAL Specific Administrative Rulings and Decisions § 100.155 Salt and iodized salt. (a) For the purposes of this section, the term iodized salt or iodized table salt is designated... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Salt and iodized salt. 100.155 Section 100.155...

  5. Detached Eddy Simulations of an Airfoil in Turbulent Inflow

    DEFF Research Database (Denmark)

    Gilling, Lasse; Sørensen, Niels; Davidson, Lars

    2009-01-01

    The effect of resolving inflow turbulence in detached eddy simulations of airfoil flows is studied. Synthetic turbulence is used for inflow boundary condition. The generated turbulence fields are shown to decay according to experimental data as they are convected through the domain with the free ...

  6. Numerical simulation of breakup and detachment of an axially ...

    Indian Academy of Sciences (India)

    It is found that the liquid bridge detachment is strongly influenced by the contact angle prescribed at the stationary and moving solid surfaces. At relatively small pulling speeds, the entire liquid is found to preferentially adhere to the less hydrophobic surface.When the prescribed contact angles are equal, however, the liquid ...

  7. Effect of detachment time of pineapple ( Ananas comosus L .) crown ...

    African Journals Online (AJOL)

    A limiting factor to large scale production of pineapple is the scarcity of planting materials. The use of pineapple crown as a propagation material is common, but with no regard to length of time after detachment. A study was conducted in the late seasons of 2007 and 2008 at the Teaching and Research Farm Ekiti State ...

  8. Functional and environmental design of detached, low crest level breakwaters

    International Nuclear Information System (INIS)

    Bricio Garberi, L.; Negro Valdecantos, V.; Diez Gonzalez, J. J.; Lopez Gutierrez, J. S.

    2010-01-01

    The research work as presented in this article covers the design of detached breakwaters since they constitute a type of coastal defense work with which to combat many of the erosion problems found on beaches in a stable, sustainable fashion. The main aim of this work is to formulate a functional and environmental (non structural) method of design enabling the fundamental characteristics of a detached breakwater to be defined as a function of the effect it is wished to induce on the coast whilst meeting social demands and preserving or improving the quality of the littoral environment. The general applicability of the method is also sought by means of considering relations between variables od different natures (climatic, geomorphologic and geometric) influencing the changes experienced on the coast after the detached breakwater has been built. The study of the relations between the different variables is carried out on the data from a abase of nineteen actual, existing detached breakwaters on the Spanish Mediterranean coastline and follows a methodology based on the implementation of non-dimensional monomials and on a search for relations of dependency between them. Finally, a discussion on the results obtained lead to a proposal for a design method that uses some of the graphic relations found between the variables studied with which the aforesaid main objective is achieved. (Author) 9 refs.

  9. Bilateral iris, choroid, optic nerve colobomas and retinal detachment ...

    African Journals Online (AJOL)

    Rabah M. Shawky

    2013-12-05

    Dec 5, 2013 ... Bilateral iris, choroid, optic nerve colobomas and retinal detachment in an Egyptian patient with mild Baraitser–Winter syndrome. Rabah M. Shawky *, Heba Salah Abd-Elkhalek Elabd, Radwa Gamal. Pediatric Department, Genetics Unit, Ain Shams University, Egypt. Received 26 October 2013; accepted 4 ...

  10. Atomic collisions: electron detachment and resonant inelastic scattering

    International Nuclear Information System (INIS)

    Ojha, P.C.

    1980-01-01

    Part I: Electron detachment in collisions of negative ions, H - + He. In conflict from the expectation from a compound state model, observation shows that the detachment cross section increases with energy in the adiabatic region below 2 keV. The compound state model is not appropriate because of a strong s-wave component in the wavefunction allows the extra electron to run away as soon as its state becomes unbound. The detachment cross section increases with the collision velocity because detachment is induced by a breakdown of the Born-Oppenheimer approximation which shifts to larger separations of the nuclei as the collision velocity increases. Part II: Resonance excitation in electron rare gas collisions. A new method is proposed for calculating the positions of resonances and cross sections in electron molecule collisions by enclosing the entire system in a spherical box, thus converting the problem to a bound state problem. It is used to calculate the energies of [np 52 P/sub 3/2,1/2/](n + l)s(n + l)p 3 P resonances in collisions of slow electrons with Ne, Ar, Kr, and Xe. The problem is simplified by invoking the Grandparent Model (that the resonances consist of two loosely bound electrons outside a compact positive ion core). The model is tested by explaining the Schulz's Law. Cross sections for excitation of Ne and Ar atoms from the ground state to the lowest metastable and uv emitting levels are calculated

  11. Endovascular therapy of arteriovenous fistulae with electrolytically detachable coils

    Energy Technology Data Exchange (ETDEWEB)

    Jansen, O.; Doerfler, A.; Forsting, M.; Hartmann, M.; Kummer, R. von; Tronnier, V.; Sartor, K. [Dept. of Neuroradiology, University of Heidelberg Medical School (Germany)

    1999-12-01

    We report our experience in using Guglielmi electrolytically detachable coils (GDC) alone or in combination with other materials in the treatment of intracranial or cervical high-flow fistulae. We treated 14 patients with arteriovenous fistulae on brain-supplying vessels - three involving the external carotid or the vertebral artery, five the cavernous sinus and six the dural sinuses - by endovascular occlusion using electrolytically detachable platinum coils. The fistula was caused by trauma in six cases. In one case Ehlers-Danlos syndrome was the underlying disease, and in the remaining seven cases no aetiology could be found. Fistulae of the external carotid and vertebral arteries and caroticocavernous fistulae were reached via the transarterial route, while in all dural fistulae a combined transarterial-transvenous approach was chosen. All fistulae were treated using electrolytically detachable coils. While small fistulae could be occluded with electrolytically detachable coils alone, large fistulae were treated by using coils to build a stable basket for other types of coil or balloons. In 11 of the 14 patients, endovascular treatment resulted in complete occlusion of the fistula; in the remaining three occlusion was subtotal. Symptoms and signs were completely abolished by this treatment in 12 patients and reduced in 2. On clinical and neuroradiological follow-up (mean 16 months) no reappearance of symptoms was recorded. (orig.)

  12. Bilateral orbital infarction and retinal detachment in a previously ...

    African Journals Online (AJOL)

    In this report, we present a case of an 11‑year‑old previously undiagnosed sickle cell disease Nigerian girl with severe acute bilateral orbital infarction and retinal detachment to highlight that hemoglobinopathy induced orbital infarction should be considered in African children with acute onset proptosis with or without ...

  13. Cataract and Retinal Detachment Following Electric Shock Injury in ...

    African Journals Online (AJOL)

    Aim: To report a case of cataract and retinal detachment following an electrical injury in an adult Nigerian male. C a se report: A 28-year-old man presented with a history of progressive and painless loss of vision in the right eye, three years after an electric shock injury. There was no history of mechanical trauma.

  14. Blindness from bilateral bullous retinal detachment: tragedy of a ...

    African Journals Online (AJOL)

    Objective: To present a scourge of blindness possibly due to an inherited condition causing retinal detachment in 3 siblings. Methods: In February 2004, three siblings from a monogamous family from Ipetu-Ijesha in Osun state, Nigerian presented to the author consecutively with history of visual impairment/ blindness.

  15. Incidence and Pattern of Retinal Detachment in a Tertiary Eye ...

    African Journals Online (AJOL)

    giant tears; 6 (6.5%) had dialysis and 3 (3.2%) had coexisting macula holes; in 73.1% the tears were located in the superior retina. Conclusions: Retinal ... factor in 33 (35.5%) patients. In no patient was the detachment restricted to one quadrant. .... Health education of eye patients and the general public on the symptoms of ...

  16. Bilateral Serous Retinal Detachment as a Complication of ...

    African Journals Online (AJOL)

    preeclampsia and eclampsia for ocular manifestations, which should be helpful for obstetrician in the management of patient. disks (ODs), macula, and tortuous retinal vessels. Bilateral exudative retinal detachments (RD) were detected superotemporal and inferotemporal to the. ODs involving the macula [Figures 1 and 2].

  17. Turbulent Simulations of Divertor Detachment Based On BOUT + + Framework

    Science.gov (United States)

    Chen, Bin; Xu, Xueqiao; Xia, Tianyang; Ye, Minyou

    2015-11-01

    China Fusion Engineering Testing Reactor is under conceptual design, acting as a bridge between ITER and DEMO. The detached divertor operation offers great promise for a reduction of heat flux onto divertor target plates for acceptable erosion. Therefore, a density scan is performed via an increase of D2 gas puffing rates in the range of 0 . 0 ~ 5 . 0 ×1023s-1 by using the B2-Eirene/SOLPS 5.0 code package to study the heat flux control and impurity screening property. As the density increases, it shows a gradually change of the divertor operation status, from low-recycling regime to high-recycling regime and finally to detachment. Significant radiation loss inside the confined plasma in the divertor region during detachment leads to strong parallel density and temperature gradients. Based on the SOLPS simulations, BOUT + + simulations will be presented to investigate the stability and turbulent transport under divertor plasma detachment, particularly the strong parallel gradient driven instabilities and enhanced plasma turbulence to spread heat flux over larger surface areas. The correlation between outer mid-plane and divertor turbulence and the related transport will be analyzed. Prepared by LLNL under Contract DE-AC52-07NA27344. LLNL-ABS-675075.

  18. Numerical simulation of breakup and detachment of an axially ...

    Indian Academy of Sciences (India)

    Kishore Singh Patel

    Abstract. The extensional, breakup and detachment dynamics of an axially stretching Newtonian liquid bridge are investigated numerically with a dynamic domain multiphase incompressible flow solver. The mul- tiphase flow solver employs a Cahn–Hilliard phase field model to describe the evolution of the diffuse interface.

  19. Silicone oil removal after rhegmatogenous retinal detachment: comparing techniques

    NARCIS (Netherlands)

    Tan, H. S.; Dell'omo, R.; Mura, M.

    2012-01-01

    Purpose To assess the outcome of silicone oil removal after rhegmatogenous retinal detachment (RRD) surgery, and to compare results of a two-port (infusion-extraction) versus a three-port (full vitrectomy) approach. Methods Primary outcome measure was the rate of redetachment. Secondary outcome

  20. Air versus gas tamponade in retinal detachment surgery

    NARCIS (Netherlands)

    Tan, H. Stevie; Oberstein, Sarit Y. Lesnik; Mura, Marco; Bijl, Heico M.

    2013-01-01

    Objective To compare the outcome of air tamponade with gas tamponade in primary vitrectomy for the treatment of rhegmatogenous retinal detachment (RRD). Methods We examined the records of 524 cases of 523 patients that underwent primary vitrectomy for RRD with air or sulphur hexafluoride 20% gas

  1. Peripheral 360 degrees retinectomy in complex retinal detachment.

    Science.gov (United States)

    Banaee, Touka; Hosseini, Seyyedeh Maryam; Eslampoor, Alireza; Abrishami, Majid; Moosavi, Mirnaghi

    2009-06-01

    To report the functional and anatomical results and complications of 360 degrees peripheral retinectomy for management of complicated retinal detachment. Patients with complicated retinal detachment underwent pars plana vitrectomy, 360 degrees retinectomy, intraoperative endolaser, and internal tamponade with silicone oil. Postoperative visual acuity, intraocular pressure, retinal status, need for reoperation, and complications are presented. Twenty eyes of 19 patients with a mean age of 32.4 years (8-75 years) underwent pars plana vitrectomy and 360 degrees peripheral retinectomy for complicated retinal detachment due to anterior proliferative vitreoretinopathy, unstable edge of retinal break, anterior hyaloidal fibrovascular proliferation, retinal incarceration in scleral wound, and 300 degrees giant retinal tear. Intraoperative reattachment was achieved in 18 eyes. Mean postoperative follow-up time was 24.2 months (2-70 months). Retina was attached in 14 eyes (70%) in the last visit. Eight eyes (40%) had 5/200 or greater visual acuity. Preoperative and postoperative visual acuities did not have significant correlation (Spearman correlation coefficient = 0.291). There was no relation between diagnosis and anatomical outcome (P > 0.2). Relaxing peripheral 360 degrees retinectomy is an effective procedure for flattening the retina in complicated retinal detachments when no other option is available.

  2. Elucidation of the genetic causes of retinal detachment

    NARCIS (Netherlands)

    Go, S.L.

    2006-01-01

    Rhegmatogenous retinal detachment (RRD) is caused by a break in the neurosensory retina of the eye, thereby allowing fluid from the vitreous space into the space between the sensory retina and the retinal pigment epithelium. Untreated, this disorder can lead to blindness. A case-control study in

  3. Bilateral Rhegmatogenous Retinal Detachment during External Beam Radiotherapy

    Directory of Open Access Journals (Sweden)

    Takako Hidaka

    2016-06-01

    Full Text Available Herein, we report a case of nontraumatic bilateral rhegmatogenous retinal detachment (RRD during external beam radiotherapy for nonocular tumor, presented as an observational case study in conjunction with a review of the relevant literature. A 65-year-old male was referred to our hospital due to bilateral RRD. He underwent a biopsy for a tumor of the left frontal lobe 4 months prior to presentation, and the tumor had been diagnosed as primary central nerve system B-cell type lymphoma. He received chemotherapy and external beam radiotherapy for 1 month. There were no traumatic episodes. Bilateral retinal detachment occurred during a series of radiotherapies. Simultaneous nontraumatic bilateral retinal detachment is rare. The effects of radiotherapy on ocular functionality, particularly in cases involving retinal adhesion and vitreous contraction, may include RRD. Thus, it is necessary to closely monitor the eyes of patients undergoing radiotherapy, particularly those undergoing surgery for retinal detachment and those with a history of photocoagulation for retinal tears, a relevant family history, or risk factors known to be associated with RRD.

  4. [Surgical treatment of very advanced rhegmatogenous retinal detachment].

    Science.gov (United States)

    Hejsek, L; Ernest, J; Němec, P; Rejmont, L; Manethová, K; Stepanov, A; Rozsíval, P

    2013-12-01

    Rhegmatogenous retinal detachment is a serious ocular pathology. Therapeutic options are surgical only. Surgery is in advanced stages technically and financially demanding. In this paper, we consider the results operated detachments, which were for their advancement, with respect to the technical possibilities of the present intraocular surgery, on the border of the surgical possibilities. The group consisted of 37 eyes of 37 patients who were followed prospectively and had in the affected eye very advanced (old) rhegmatogenous retinal detachment. As a method to confirtm any visual functions were used visual evoked potentials in flash monocular stimulation (F-VEP). All patients had a cerclage performed 12 mm from the limbus, 20G pars plana vitrectomy (PPV), in 2 was also performed cataract surgery (phacoemulsification with implantation of an artificial intraocular lens to the bag). Surgery was done in 23 of 37 patients (62 % of the whole group), with the remaining 14 eyes was not due to the severity of finding highly advanced retinal detachment. Attached retina at the end of the observation period had 14 eyes (61% of the patients, 38% of the whole group). In 5 eyes was due to local re-detachment in the periphery only stabilized finding (22% of operated eyes, 14% of all). The values ​​of visual acuity in the subgroup of operated eyes were statistically significantly increased after surgery (Wilcoxon p = 0.036). The values ​​of F-VEP were not statistically significantly different between operated and non-operated patients and was not found any statistically significant correlation between the vision (and even after surgery) and F-VEP in operated eyes. Anatomical success of surgical treatment of advanced retinal detachment is possible. But the correlation was not found in visual acuity and F-VEP or the severity of preoperative disturbed visual function, even in the improvement in the postoperative period. F-VEP is not a suitable marker for determining the

  5. Seismic Slip on an Oblique Detachment Fault at Low Angles

    Science.gov (United States)

    Janecke, S. U.; Steely, A. N.; Evans, J. P.

    2008-12-01

    Pseudotachylytes are one of the few accepted indicators of seismic slip along ancient faults. Low-angle normal faults have produced few large earthquakes in historic times and low-angle normal faults (detachment faults) are typically severely misoriented relative to a vertical maximum compressive stress. As a result many geoscientists question whether low-angle normal faults produce earthquakes at low angles. Relationships in southern California show that a major low-angle normal-oblique fault slipped at low angles and produced large earthquakes. The exhumed Late Cenozoic West Salton detachment fault preserves spectacular fault- related pseudotachylytes along its fault plane and injected into its hanging wall and footwall. Composite pseudotachylyte zones are up to 1.25 m thick and persists over lateral distances of at least 10's of meters. Pseudotachylyte is common in most thin sections of damaged fault rocks with more than 20% (by volume) of cataclasite. We recognized the presence of original melt using numerous criteria: abundant spherulites in thin sections, injection structures at both the thin-section and outcrop scale, black aphanitic textures, quenched vein margins, variations in microcrystallite textures and/or size with respect to the vein margin, and glassy textures in hand sample. Multiple earthquakes are inferred to produce the layered "stratigraphy" in some exposures of pseudotachylytes. We infer that the West Salton detachment fault formed and slipped at low angles because it nearly perfectly reactivates a Cretaceous ductile thrust system at the half km scale and dips between 10 and 45 degrees. The about 30 degree NNE dip of the detachment fault on the north side of Yaqui Ridge is likely steeper than its dip during detachment slip because there is local steepening on the flanks of the Yaqui Ridge antiform in a contractional stepover of a crosscutting Quaternary San Felipe dextral fault zone. These relationships indicate a low dip on the detachment

  6. Thermofusion of the retina with the RPE to seal tears during retinal detachment repair.

    Science.gov (United States)

    Heriot, Wilson J

    2016-04-01

    To develop an animal model to test the hypothesis that immediate adhesion of the retina to the choroid (retinopexy) can be created by elimination of the water separating the retina from the retinal pigment epithelium (RPE) prior to photocoagulation. The retina and RPE are hydrophobic lipoprotein structures separated intraoperatively by a thin layer of fluid despite surgical drainage. If the RPE and retina are contacting, heating should create a unified local coagulum and achieve instantaneous fusing of the retina and RPE, thus sealing the subretinal space around the retinal tear. The surgical technique and histological findings in a rabbit model of rhegmatogenous retinal detachment (RRD) are reported here. Nine Dutch-belted, pigmented rabbits underwent vitrectomy with lensectomy, creation of localised retinal detachment by subretinal injection of balanced salt solution (BSS), enlargement of the hole and fluid-gas exchange to "re-attach" the retina. Dehydration of the retina surrounding the hole was achieved by an airstream from a flute needle. A laser (810 nm) was applied in long pulses to achieve a mild retinal reaction around the hole in the dehydrated adjacent retina. The BSS irrigation was resumed. Eyes were then enucleated and the treated retina examined histologically. The dehydrated and lasered retinal tear margin demonstrated fusion of the retina with the RPE/choroid. The non-dehydrated adjacent areas showed thermal tissue changes in the retina, RPE/choroid and adjacent sclera but remained separated by persistent subretinal fluid and no fusion or unified coagulum developed. Immediate laser-induced thermal fusion of the retina with the RPE at the margin of a retinal tear can be achieved by removing the subretinal fluid prior to photocoagulation. The integrated coagulum seals the tear margin preventing further fluid entering the subretinal space, thus correcting the cause of RRD. This method may facilitate RRD repair without buckling or internal tamponade.

  7. Not Salt Taste Perception but Self-Reported Salt Eating Habit Predicts Actual Salt Intake

    OpenAIRE

    Lee, Hajeong; Cho, Hyun-Jeong; Bae, Eunjin; Kim, Yong Chul; Kim, Suhnggwon; Chin, Ho Jun

    2014-01-01

    Excessive dietary salt intake is related to cardiovascular morbidity and mortality. Although dietary salt restriction is essential, it is difficult to achieve because of salt palatability. However, the association between salt perception or salt eating habit and actual salt intake remains uncertain. In this study, we recruited 74 healthy young individuals. We investigated their salt-eating habits by questionnaire and salt taste threshold through a rating scale that used serial dilution of a s...

  8. Increased glutamate levels in the vitreous of patients with retinal detachment

    NARCIS (Netherlands)

    Diederen, R.; Heij, La E.C.; Deutz, N.E.P.; Kijlstra, A.; Kessels, A.G.H.; Eijk, van H.M.; Liem, A.T.A.; Dieudonne, S.; Hendrikse, F.

    2006-01-01

    Experimental models have implicated glutamate in the irreversible damage to retinal cells following retinal detachment. In this retrospective study we investigated a possible role for glutamate and other amino acid neurotransmitters during clinical rhegmatogenous retinal detachment (RRD). Undiluted

  9. Epidemiologic characteristics of retinal detachment surgery at a specialized unit in Denmark

    DEFF Research Database (Denmark)

    Poulsen, Christina Doefler; Peto, Tunde; Grauslund, Jakob

    2016-01-01

    PURPOSE: To examine the incidence of retinal detachments and to evaluate patient profiles and surgical characteristics. METHODS: Retrospective review of patients operated for primary retinal detachment (RD) and redetachment between 2010 and 2012 at the Department of Ophthalmology, Odense Universi...

  10. Apical atrophy of retinal pigment epithelial detachments in central serous chorioretinopathy

    DEFF Research Database (Denmark)

    Pryds, Anders; Hamann, Steffen; Larsen, Michael

    2012-01-01

    compatible with CSC. RESULTS: A juxtafoveal retinal pigment epithelial detachment with apical atrophy of the retinal pigment epithelium with corresponding severe attenuation of the pigmentation of the retinal pigment epithelium was observed in both patients. One of the patients presented with a serous...... neurosensory retinal detachment with smokestack leakage 7 years after first being seen. The other patient was never seen with a neurosensory detachment. CONCLUSION: Isolated pigment epithelial detachment with apical retinal pigment epithelial atrophy may represent a precursor stage of CSC....

  11. Cyclic GMP in the pig vitreous and retina after experimental retinal detachment

    NARCIS (Netherlands)

    Diederen, R.; Heij, La E.C.; Lemmens, M.A.M.; Kijlstra, A.; Vente, De J.; Hendrikse, F.

    2008-01-01

    Purpose: Earlier studies have revealed a decreased level of cGMP in vitreous fluid obtained from patients with a retinal detachment. To further investigate this phenomenon, we developed an experimental retinal detachment model in pigs. Methods: Experimental unilateral retinal detachments were

  12. Characteristics of rhegmatogenous retinal detachment and their relationship to success rates of surgery.

    Science.gov (United States)

    Williamson, Tom H; Lee, Edward J K; Shunmugam, Manoharan

    2014-07-01

    To determine features of rhegmatogenous retinal detachment predictive of anatomical success with surgical procedure. All patients undergoing surgery at a tertiary referral practice had contemporaneous data collection in an electronic database. Overall, 847 eyes from 847 patients undergoing surgical procedure for rhegmatogenous retinal detachment were included in this study. Mean age was 62.2 years with 60% male subjects and 56% right eyes. Mean postoperative follow-up was 9.6 months (range, 6 weeks to 10 years). With univariate analysis, the presence of superotemporal breaks was associated with a reduction in the chance of failed primary surgery (P = 0.005); detached inferonasal breaks (P = 0.002), proliferative vitreoretinopathy (PVR) (P detached inferior retina (P detachment (P detached inferior breaks, increased number of breaks, and 4-quadrant detachment remained associated with an increased risk of failure, and superotemporal detached breaks with the reduced risk of failure (r(2) = 0.08). For patients without PVR, only inferonasal detached breaks and 3 to 4 quadrants of detachment remained predictive of failure (r(2) = 0.04). For patients with PVR (n = 120), multivariate analysis showed that PVR C4-12 and posterior breaks increased the failure risk and detached superotemporal breaks reduced the risk of failure (r(2) = 0.22). Number of breaks, inferior positioning of breaks, the extent of rhegmatogenous retinal detachment, and PVR are associated with failed primary surgery.

  13. Submarine Salt Karst Terrains

    Directory of Open Access Journals (Sweden)

    Nico Augustin

    2016-06-01

    Full Text Available Karst terrains that develop in bodies of rock salt (taken as mainly of halite, NaCl are special not only for developing in one of the most soluble of all rocks, but also for developing in one of the weakest rocks. Salt is so weak that many surface-piercing salt diapirs extrude slow fountains of salt that that gravity spread downslope over deserts on land and over sea floors. Salt fountains in the deserts of Iran are usually so dry that they flow at only a few cm/yr but the few rain storms a decade so soak and weaken them that they surge at dm/day for a few days. We illustrate the only case where the rates at which different parts of one of the many tens of subaerial salt karst terrains in Iran flows downslope constrains the rates at which its subaerial salt karst terrains form. Normal seawater is only 10% saturated in NaCl. It should therefore be sufficiently aggressive to erode karst terrains into exposures of salt on the thousands of known submarine salt extrusions that have flowed or are still flowing over the floors of hundreds of submarine basins worldwide. However, we know of no attempt to constrain the processes that form submarine salt karst terrains on any of these of submarine salt extrusions. As on land, many potential submarine karst terrains are cloaked by clastic and pelagic sediments that are often hundreds of m thick. Nevertheless, detailed geophysical and bathymetric surveys have already mapped likely submarine salt karst terrains in at least the Gulf of Mexico, and the Red Sea. New images of these two areas are offered as clear evidence of submarine salt dissolution due to sinking or rising aggressive fluids. We suggest that repeated 3D surveys of distinctive features (± fixed seismic reflectors of such terrains could measure any downslope salt flow and thus offer an exceptional opportunity to constrain the rates at which submarine salt karst terrains develop. Such rates are of interest to all salt tectonicians and the many

  14. A history of salt.

    Science.gov (United States)

    Cirillo, M; Capasso, G; Di Leo, V A; De Santo, N G

    1994-01-01

    The medical history of salt begins in ancient times and is closely related to different aspects of human history. Salt may be extracted from sea water, mineral deposits, surface encrustations, saline lakes and brine springs. In many inland areas, wood was used as a fuel source for evaporation of brine and this practice led to major deafforestation in central Europe. Salt played a central role in the economies of many regions, and is often reflected in place names. Salt was also used as a basis for population censuses and taxation, and salt monopolies were practised in many states. Salt was sometimes implicated in the outbreak of conflict, e.g. the French Revolution and the Indian War of Independence. Salt has also been invested with many cultural and religious meanings, from the ancient Egyptians to the Middle Ages. Man's innate appetite for salt may be related to his evolution from predominantly vegetarian anthropoids, and it is noteworthy that those people who live mainly on protein and milk or who drink salty water do not generally salt their food, whereas those who live mainly on vegetables, rice and cereals use much more salt. Medicinal use tended to emphasize the positive aspects of salt, e.g. prevention of putrefaction, reduction of tissue swelling, treatment of diarrhea. Evidence was also available to ancient peoples of its relationship to fertility, particularly in domestic animals. The history of salt thus represents a unique example for studying the impact of a widely used dietary substance on different important aspects of man's life, including medical philosophy.

  15. Abrupt tectonics and rapid slab detachment with grain damage.

    Science.gov (United States)

    Bercovici, David; Schubert, Gerald; Ricard, Yanick

    2015-02-03

    A simple model for necking and detachment of subducting slabs is developed to include the coupling between grain-sensitive rheology and grain-size evolution with damage. Necking is triggered by thickened buoyant crust entrained into a subduction zone, in which case grain damage accelerates necking and allows for relatively rapid slab detachment, i.e., within 1 My, depending on the size of the crustal plug. Thick continental crustal plugs can cause rapid necking while smaller plugs characteristic of ocean plateaux cause slower necking; oceanic lithosphere with normal or slightly thickened crust subducts without necking. The model potentially explains how large plateaux or continental crust drawn into subduction zones can cause slab loss and rapid changes in plate motion and/or induce abrupt continental rebound.

  16. Evaluation of metal trace detachment from dosing pumps using PIXE

    Energy Technology Data Exchange (ETDEWEB)

    Lozano, Omar, E-mail: omar.lozanogarcia@unamur.be [Research Centre for the Physics of Matter and Radiation (PMR), Namur Nanosafety Centre (NNC), Namur Research Institute for Life Sciences - NARILIS, University of Namur - UNamur, Rue de Bruxelles 61, B-5000 Namur (Belgium); Mejia, Jorge [Research Centre for the Physics of Matter and Radiation (PMR), Namur Nanosafety Centre (NNC), Namur Research Institute for Life Sciences - NARILIS, University of Namur - UNamur, Rue de Bruxelles 61, B-5000 Namur (Belgium); Laloy, Julie; Alpan, Lütfiye [Namur Thrombosis and Hemostasis Centre (NTHC), Namur Nanosafety Centre (NNC), Namur Research Institute for Life Sciences - NARILIS, University of Namur - UNamur, Rue de Bruxelles 61, B-5000 Namur (Belgium); Toussaint, Olivier [Laboratory of Biochemistry and Cellular Biology (URBC), Namur Nanosafety Centre (NNC), Namur Research Institute for Life Sciences - NARILIS, University of Namur - UNamur, Rue de Bruxelles 61, B-5000 Namur (Belgium); Dogné, Jean-Michel [Namur Thrombosis and Hemostasis Centre (NTHC), Namur Nanosafety Centre (NNC), Namur Research Institute for Life Sciences - NARILIS, University of Namur - UNamur, Rue de Bruxelles 61, B-5000 Namur (Belgium); Lucas, Stéphane [Research Centre for the Physics of Matter and Radiation (PMR), Namur Nanosafety Centre (NNC), Namur Research Institute for Life Sciences - NARILIS, University of Namur - UNamur, Rue de Bruxelles 61, B-5000 Namur (Belgium)

    2014-07-15

    Metal trace detachment evaluation is essential for instruments destined for pharmaceutical applications, such as pumps. Particle-Induced X-ray Emission (PIXE) was used to determine and quantify metal traces originated from stainless steel and ceramic dosing pumps. Metal traces were quantified from either distilled water samples or cellulose filters in two tests: a short-term test of 16 h mimicking a daily cycle of a dosing pump for industrial applications, and a long-term test of 9 days evaluating the pump wearing. The main result is that ceramic dosing pumps present lower metal detachment than stainless steel counterparts. Traces of Si and Al were found originating from pieces around the pumps (pipes and joints)

  17. Intellectual property rights and detached human body parts.

    Science.gov (United States)

    Pila, Justine

    2014-01-01

    This paper responds to an invitation by the editors to consider whether the intellectual property (IP) regime suggests an appropriate model for protecting interests in detached human body parts. It begins by outlining the extent of existing IP protection for body parts in Europe, and the relevant strengths and weaknesses of the patent system in that regard. It then considers two further species of IP right of less obvious relevance. The first are the statutory rights of ownership conferred by domestic UK law in respect of employee inventions, and the second are the economic and moral rights recognised by European and international law in respect of authorial works. In the argument made, both of these species of IP right may suggest more appropriate models of sui generis protection for detached human body parts than patent rights because of their capacity better to accommodate the relevant public and private interests in respect of the same.

  18. Fruit Detachment and Classification Method for Strawberry Harvesting Robot

    Directory of Open Access Journals (Sweden)

    Guo Feng

    2008-03-01

    Full Text Available Fruit detachment and on-line classification is important for the development of harvesting robot. With the specific requriements of robot used for harvesting strawberries growing on the ground, a fruit detachment and classification method is introduced in this paper. OHTA color spaces based image segmentation algorithm is utilized to extract strawberry from background; Principal inertia axis of binary strawberry blob is calculated to give the pose information of fruit. Strawberry is picked selectively according to its ripeness and classified according to its shape feature. Histogram matching based method for fruit shape judgment is introduced firstly. Experiment results show that this method can achieve 93% accuracy of strawberry's stem detection, 90% above accuracy of ripeness and shape quality judgment on black and white background. With the improvement of harvesting mechanism design, this method has application potential in the field operation.

  19. Phosphorus 32P test in primary retinal detachment

    International Nuclear Information System (INIS)

    Mondelski, S.; Pytlarz, E.

    1980-01-01

    In 20 patients with primary retinal detachment the 32 P radioisotope test was performed injecting intravenously 500-750 μCi of the isotope and doing measurements with a F-Messeelektronik counter after 48 and 72 hours. The radioisotope index calculated at the site of greater detachment in 17 eye-balls in relation to the sites with apposed retina in the same eye or the other eye differed in these cases. Among the obtained results the large number of negative indices calls for attention (12 out of 17 cases) and in 2 cases the obtained values were +30 and +59 which may cause diagnostic errors in cases with suspected intraocular neoplasm. (author)

  20. Phosphorus /sup 32/P test in primary retinal detachment

    Energy Technology Data Exchange (ETDEWEB)

    Mondelski, S.; Pytlarz, E. (Akademia Medyczna, Poznan (Poland))

    1980-01-01

    In 20 patients with primary retinal detachment the /sup 32/P radioisotope test was performed injecting intravenously 500-750 ..mu..Ci of the isotope and doing measurements with a F-Messeelektronik counter after 48 and 72 hours. The radioisotope index calculated at the site of greater detachment in 17 eye-balls in relation to the sites with apposed retina in the same eye or the other eye differed in these cases. Among the obtained results the large number of negative indices calls for attention (12 out of 17 cases) and in 2 cases the obtained values were +30 and +59 which may cause diagnostic errors in cases with suspected intraocular neoplasm.

  1. Worth its salt?

    Science.gov (United States)

    The idea that all underground salt deposits can serve as storage sites for toxic and nuclear waste does not always hold water—literally. According to Daniel Ronen and Brian Berkowitz of Israel's Weizmann Institute of Science and Yoseph Yechieli of the Geological Survey of Israel, some buried salt layers are in fact highly conductive of liquids, suggesting that wastes buried in their confines could easily leech into groundwater and nearby soil.When drilling three wells into a 10,000-year-old salt layer near the Dead Sea, the researchers found that groundwater had seeped into the layer and had absorbed some of its salt.

  2. Timing of acute macula-on rhegmatogenous retinal detachment repair.

    Science.gov (United States)

    Ehrlich, Rita; Niederer, Rachael L; Ahmad, Nadeem; Polkinghorne, Philip

    2013-01-01

    To determine if same-day or next available surgery changed the outcome of patients presenting with acute macula-on rhegmatogenous retinal detachments. A retrospective review of patients presenting with acute macula-on rhegmatogenous retinal detachments treated with small-gauge vitrectomy was performed. Data collection included subjects' demographics, duration of symptoms, location and extent of the retinal detachment, and timing of surgery. The primary outcome was anatomical and functional success rate for patients having same-day surgery compared with those for whom surgery was delayed. One hundred and fourteen patients were included in this study. Sixty-two patients operated on day of presentation, 46 patients operated the day after presentation, and in 6 patients, surgery was delayed from 2 to 5 days. Time to surgery in hours ranged between 1 and 120 hours (mean 14.5 ± 15.05 hours). Retinal reattachment was achieved in 95.6% of patients, with 80% requiring only one procedure. Mean initial visual acuity was logarithm of the minimum angle of resolution 0.42 (SD 0.6), and mean final visual acuity was logarithm of the minimum angle of resolution 0.39 (SD 0.67) (P = 0.53). Time to surgery was not found to effect final anatomical outcome (P = 0.56). No statistically significant association was observed between change in visual acuity and time to surgery (P = 0.99). Modest delay in timing of surgery for macula-on rhegmatogenous retinal detachment did not adversely impact on patients' outcome.

  3. Primary rhegmatogenous retinal detachment - surgical methods and anatomical outcome.

    Science.gov (United States)

    Haugstad, Marta; Moosmayer, Stefan; Bragadόttir, Ragnheiður

    2017-05-01

    The aim of the study was to evaluate the anatomical success of surgical management of primary rhegmatogenous retinal detachment (RRD) and to compare the anatomical outcomes from different surgical techniques. During 2012, 517 consecutive eyes (514 patients) were operated by 11 surgeons at the Department of Ophthalmology, Oslo University Hospital. Patient records were retrospectively analysed with no exclusions. Main outcome measures were primary and final anatomical success. Primary anatomical success was defined as retinal reattachment 6 months after primary surgery with reoperations excluded. Final anatomical success was defined as retinal reattachment 6 months after primary surgery with reoperations included. Incidence of RRD was 18.6 eyes per 100 000 person-years. The macula was detached in 50.5% of the eyes at baseline. Of 517 operated eyes, 317 (61.3%) underwent pars plana vitrectomy (PPV), 23 (4.5%) pars plana vitrectomy together with a scleral buckle (PPV-SB), 175 (33.9%) scleral buckle (SB) surgery and two (0.4%) pneumatic retinopexy (PR). Primary anatomical success was 89.0% in the PPV group, 87.0% in the PPV-SB group and 85.7% in the SB group. Final anatomical success was 98.1% in the PPV group, 100% in the PPV-SB group and 99.4% in the SB group. Factors which were correlated to the redetachment were detachment of more than 6 clock hours (p = 0.003) and visual acuity (VA) on Snellen chart retina were large detachment and low VA. © 2016 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  4. PRIMARY SCLERAL BUCKLING FOR PEDIATRIC RHEGMATOGENOUS RETINAL DETACHMENT.

    Science.gov (United States)

    Errera, Marie-Hélène; Liyanage, Sidath E; Moya, Rene; Wong, S Chien; Ezra, Eric

    2015-07-01

    To evaluate the anatomical outcomes of primary scleral buckling (SB) procedures for pediatric rhegmatogenous retinal detachments. Retrospective consecutive case series. One hundred and four eyes of 99 consecutive nonselected pediatric patients undergoing primary SB were identified. Baseline factors recorded were demographics, presenting clinical examination findings, previous ocular surgery, predisposing factors. Intraoperative factors recorded were the type of buckle, number and distribution of retinal breaks, number of retinal quadrants detached, macular status (involved vs. uninvolved), the use of subretinal fluid drainage, and surgical complications. Anatomical reattachment rate at last follow-up. Subgroup analysis was carried out to identify any predisposing factors for failure of primary surgery, effect of age on outcome, intraoperative pathology, effect of posterior versus anterior SB, and redetachment and secondary-procedure complications specific to SB. The initial surgery was segmental SB alone in 87 eyes (83.6%). Retinal reattachment was achieved with 1 operation in 73% (76 of 104 eyes). Of the 28 cases that redetached, 14 eyes underwent a repeat SB procedure (success rate of this second operation: 85.7% [12 of 14 eyes]), 13 eyes underwent vitrectomy (success rate of this second operation: 38.4% [5 of 13 eyes]), and 1 case was not reoperated. Overall, the final success rate was 94% (98 of 104 eyes). Factors associated with a statistically significant increased risk of failure included more than one break; three or more quadrants of detachment; horseshoe tears; no breaks seen on preoperative examination; Stickler syndrome. In selected cases, primary SB is an effective treatment for pediatric, rhegmatogenous retinal detachment.

  5. Success Rates of Vitrectomy in Treatment of Rhegmatogenous Retinal Detachment

    OpenAIRE

    Mohamed, Yasser Helmy; Ono, Kozue; Kinoshita, Hirofumi; Uematsu, Masafumi; Tsuiki, Eiko; Fujikawa, Azusa; Kitaoka, Takashi

    2016-01-01

    Aim. To investigate the anatomical success rates of pars plana vitrectomy (PPV) after primary rhegmatogenous retinal detachment (RRD). Methods. This retrospective study was conducted between December 2008 and October 2014 at Nagasaki University Hospital. The preoperative data recorded included the lens status, location of the retinal tear, whether a tear was visualized, presence of multiple tears, macula status, presence of peripheral lattice retinal degeneration, and best-corrected visual ac...

  6. Natural ionization orbitals for interpreting electron detachment processes

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, Lee M.; Harb, Hassan; Hratchian, Hrant P., E-mail: hhratchian@ucmerced.edu [Chemistry and Chemical Biology, University of California, Merced, California 95343 (United States)

    2016-05-28

    A compact orbital representation of ionization processes is described utilizing the difference of calculated one-particle density matrices. Natural orbital analysis involving this difference density matrix simplifies interpretation of electronic detachment processes and allows differentiation between one-electron transitions and shake-up/shake-off transitions, in which one-electron processes are accompanied by excitation of a second electron into the virtual orbital space.

  7. Lowest auto-detachment state of the water anion

    International Nuclear Information System (INIS)

    Houfek, K.; Cizek, M.

    2016-01-01

    Because of the abundance of water in living tissue the reactive low-energy electron collisions with the water molecule represent an important step in the radiation damage of cells. In this paper, the potential energy surface of the ground state of the water anion H 2 O - is carefully mapped using multireference configuration interaction (MRCI) calculations for a large range of molecular geometries. Particular attention is paid to a consistent description of both the O - +H 2 and OH - +H asymptotes and to a relative position of the anion energy to the ground state energy of the neutral molecule. The auto-detachment region, where the anion state crosses to the electronic continuum is identified. The local minimum in the direction of the O - + H 2 channel previously reported by Werner et al. [J. Chem. Phys. 87, 2913 (1987)] is found to be slightly off the linear geometry and is separated by a saddle from the auto-detachment region. The auto-detachment region is directly accessible from the OH - +H asymptote. For the molecular geometries in the auto-detachment region and in its vicinity we also performed fixed-nuclei electron-molecule scattering calculations using the R-matrix method. Tuning of consistency of a description of the correlation energy in both the multireference CI and R-matrix calculations is discussed. Two models of the correlation energy within the R-matrix method that are consistent with the quantum chemistry calculations are found. Both models yield scattering quantities in a close agreement. The results of this work will allow a consistent formulation of the nonlocal resonance model of the water anion in a future publication

  8. Optimization of Typological Requirements for Low-Cost Detached Houses

    Science.gov (United States)

    Kuráň, Jozef

    2017-09-01

    The presented paper deals with an analysis of the legislative, hygienic, functional and operational requirements for the design of detached houses and individual dwellings in terms of typological requirements. The article also presents a sociological survey about the preferences and subjective requirements of relevant public group segments in terms of living in a detached house or an individual dwelling. The aim of the paper is to define the possibilities for the optimization of typological requirements. The optimization methods are based on principles already applied to contemporary detached house preferences and trends. The main idea is to reduce the amount of floor space, thus lowering construction and operating costs. The goal is to design an optimized floor plan, while preserving the hygienic criteria for individual residential dwellings. By applying optimization methods, a so-called rationalized and conditioned floor plan results in an individual dwelling floor plan design that can be compared to a reference model with an accurate quantification comparison. The significant sources of research are the legislative and normative requirements in the field of house construction in Slovakia, the Czech Republic and abroad.

  9. Biofilm detachment mechanisms in a liquid-fluidized bed.

    Science.gov (United States)

    Chang, H T; Rittmann, B E; Amar, D; Heim, R; Ehlinger, O; Lesty, Y

    1991-08-20

    Bed fluidization offers the possibility of gaining the advantages of fixed-film biological processes without the disadvantage of pore clogging. However, the biofilm detachment rate, due to hydrodynamics and particle-to-particle attrition, is very poorly understood for fluidized-bed biofilm processes. In this work, a two-phase fluidized-bed biofilm was operated under a constant surface loading (0.09 mg total organic carbon/cm(2) day) and with a range of bed height (H), fluid velocities (U), and support-particle concentrations (C(p)). Direct measurements were made for the specific biofilm loss rate coefficient (b(s))and the total biofilm accumulation (X(f)L(f)). A hydrodynamic model allowed independent determination of the biofilm density (X(f)), biofilm thickness (L(f)), liquid shear stress (tau), and Reynolds number (Re). Multiple regression analysis of the results showed that increased particle-to-particle attrition, proportional to C(p) and increased turbulence, described by Re, caused the biofilms to be denser and thinner. The specific detachment rate coefficient (b(s)) increased as C(p) and Re increased. Almost all of the 6, values were larger than predicted by a previous model derived for smooth biofilms on a nonfluidized surface. Therefore, the turbulence and attrition of bed fluidization appear to be dominant detachment mechanisms.

  10. [Neurotrophic keratitis after vitrectomy and circumferential endophotocoagulation for retinal detachment].

    Science.gov (United States)

    Auchère Lavayssiere, C; Lux, A-L; Degoumois, A; Stchepinsky Launay, M; Denion, E

    2016-02-01

    Circumferential (360°) endophotocoagulation is frequently implemented during vitrectomies for retinal detachment. This photocoagulation may result in neurotrophic keratitis by damaging the ciliary nerves in the suprachoroidal space on their way to the pupil. We report a series of 4 cases of neurotrophic keratitis following a circumferential endophotocoagulation. A retrospective observational case series of 4 non-diabetic patients having presented with a neurotrophic keratitis following a retinal detachment treated with vitrectomy and circumferential endophotocoagulation (532 nm) at Caen University Hospital. We report the various forms of corneal lesions and the diagnostic criteria allowing for the diagnosis of neurotrophic keratitis. Neurotrophic keratitis is caused by lesions occurring at various levels of corneal innervation. Endophotocoagulation may cause a neurotrophic keratitis by damaging the short and long ciliary nerves on their way to the pupil in the suprachoroidal space. The sequelae of this condition can limit visual recovery. Hence, it is probably advisable to screen for corneal anesthesia or severe hypesthesia following a retinal detachment treated with vitrectomy and circumferential endophotocoagulation and to implement prophylactic treatment (intensive lubricant therapy; preservative-free eye drops) if needed. The risk of neurotrophic keratitis should be weighed against the dose of laser retinopexy necessary and sufficient to obtain a sustained retinal reattachment. If circumferential endophotocoagulation is implemented, it is probably sensible to monitor corneal sensitivity and to adapt postoperative treatment if necessary. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  11. Clinical results with a detachable temporary vena cava filter

    International Nuclear Information System (INIS)

    Adamus, R.; Bolte, R.; Loose, R.

    2007-01-01

    Purpose: Evaluation of the feasibility of implantation and explantation and evaluation of the efficacy of a detachable and retrievable temporary vena cava filter. Materials and Method: The temporary vena cava filter ''OptEase'' (Cordis) is a nitinol filter derived from the ''TrapEase'' (Cordis) permanent filter, which is implantable transjugularly or transfemorally. In contrast to other temporary filters, this type can be detached and is not fixed on a catheter during implantation. Therefore, it is usable as a temporary as well as a permanent filter which can be retrieved up to 12 days after detachment with a special catheter using the loop technique. The ''OptEase'' filter was implanted in 11 patients ranging in age from 19 to 82 (mean age 30 years). In 10 patients the filter was transfemorally implanted and explanted. In 1 patient implantation was performed transjugularly prior to surgery and explantation was performed transfemorally after surgery. All patients had a deep vein thrombosis or iliac vein thrombosis. In 3 patients the filter was implanted prior to surgery. In 2 patients pulmonary embolism was identified. In 5 patients the filter was implanted prophylactically because of deep vein thrombosis according to interdisciplinary diagnosis. Results: No pulmonary embolism occurred during implantation. All filters were able to be retrieved without complications using the loop technique on the 6th, 8th, 12th and 13th day. No captured thrombus material was in the filter. (orig.)

  12. Socioeconomic Barriers to Rhegmatogenous Detachment Surgery in Brazil

    Directory of Open Access Journals (Sweden)

    Pedro Carlos Carricondo

    2014-01-01

    Full Text Available Purpose. To verify access barriers patients with retinal detachment face to arrive at a reference center and to evaluate patients’ knowledge about the disease. Methods. Transversal study that applied a questioner to 65 patients of the Clinical Hospital of the University of Sao Paulo with retinal detachment between February and August of 2010. Results. Reasons for not performing the surgery in other services were as follows: 47% were referred because there was not vitreoretinal surgeon at original service; 27% could not afford the surgery, had no health insurance, or had no coverage at health insurance plan for the procedure. Time between the first symptom and the arrival at our service was as follows: 18 patients arrived in up to 7 days; 35 between 8 and 30 days; 8 between 31 and 90 days; 5 in more than 90 days. Reasons for delay were as follows: 70% did not know how serious the pathology was; 56% thought that it had spontaneous cure; 16% did not have money to pay for ophthalmic evaluation, 10% did not know where to go and 24% for other reasons. Conclusion. Educational programs about disease and measures to optimize the referral to specialized services are needed to accelerate the treatment of patients with rhegmatogenous retinal detachment.

  13. Retinal Detachment in Down Syndrome: Characteristics and Surgical Outcomes

    Directory of Open Access Journals (Sweden)

    Badr O. AlAhmadi

    2016-01-01

    Full Text Available Purpose. To determine the functional and anatomic outcomes of rhegmatogenous retinal detachment (RRD surgery in patients with Down syndrome. Methods. A retrospective chart review was performed of patients with Down syndrome who had undergone surgery for RRD at King Khalid Eye Specialist Hospital between 1995 and 2014. Results. A total of 245 patients with Down syndrome were evaluated during the study period. Eighteen eyes of 15 patients (6.1% with RRD were identified. Three out of 15 patients (20% presented with bilateral retinal detachment. All eyes presented with macula off retinal detachment. The retina was successfully reattached in 16/18 (88.8% eyes after a mean follow-up of 48 months. The final postoperative visual acuity ranged from light perception to 20/125 (median: hand motion (11/18 eyes. Conclusions. The anatomic success rate of retinal reattachment surgery in patients with Down syndrome is comparable to the general population. Patients with Down syndrome should undergo regular ophthalmic examinations for early diagnosis. Despite late diagnosis and the presence of proliferative vitreoretinopathy (PVR in some patients, favorable anatomical outcomes can be achieved.

  14. Complex descemet′s membrane tears and detachment during phacoemulsification

    Directory of Open Access Journals (Sweden)

    Faik Orucoglu

    2015-01-01

    Full Text Available Purpose: To report a case of complex Descemet′s membrane detachment (DMD and tears during phacoemulsification cataract surgery. Case Report: A 64-year-old woman underwent phacoemulsification surgery in her right eye and developed tears and partial loss of Descemet′s membrane (DM while the aspiration port was inserted through the main incision. Massive corneal edema obscured the view and the anterior chamber was barely visible the following day. Scheimpflug imaging was used to complement slit lamp examination in the postoperative period. Frequent topical corticosteroid drops were initiated. After 5 days of treatment, multiple tears and detachment of DM were visible and the anterior chamber was filled with air. After 5 weeks, the cornea regained much of its clarity despite large DM tears and focal loss of DM. Conclusion: Despite partial loss of DM, the corneal edema mostly disappeared after 5 weeks of air bubble injection. Scheimpflug imaging was beneficial in the diagnosis and monitoring of DM tears and detachments.

  15. New Light Curve Analysis for Large Numbers of Eclipsing Binaries I. Detached and Semi-Detached Binaries

    Directory of Open Access Journals (Sweden)

    Young-Woon Kang

    2010-06-01

    Full Text Available Several survey observations have produced light curves of more than five thousand eclipsing binaries for last 15 years. Future missions such as the Large Synoptic Survey Telescope (LSST, the Panoramic Survey Telescope and Rapid Response System (Pan-STARRS and Gaia are expected to yield hundreds thousands of new variable stars and eclipsing binaries. Current methods require a week to analyze the light curves of an eclipsing binary for its physical and orbital parameters. The current methods of analyzing the light curves will be inadequate to treat the overwhelming influx of new data. Therefore we developed a new method to treat large numbers of light curves of eclipsing binaries. We tested the new method by analyzing more than one hundred light curves of the detached and semi-detached eclipsing binaries discovered in the Small Magellan Cloud and present their fitted light curves with observations.

  16. Programmed subcellular release to study the dynamics of cell detachment

    Science.gov (United States)

    Wildt, Bridget

    Cell detachment is central to a broad range of physio-pathological changes however there are no quantitative methods to study this process. Here we report programmed subcellular release, a method for spatially and temporally controlled cellular detachment and present the first quantitative results of the detachment dynamics of 3T3 fibroblasts at the subcellular level. Programmed subcellular release is an in vitro technique designed to trigger the detachment of distinct parts of a single cell from a patterned substrate with both spatial and temporal control. Subcellular release is achieved by plating cells on an array of patterned gold electrodes created by standard microfabrication techniques. The electrodes are biochemically functionalized with an adhesion-promoting RGD peptide sequence that is attached to the gold electrode via a thiol linkage. Each electrode is electrically isolated so that a subcellular section of a single cell spanning multiple electrodes can be released independently. Upon application of a voltage pulse to a single electrode, RGD-thiol molecules on an individual electrode undergo rapid electrochemical desorption that leads to subsequent cell contraction. The dynamics of cell contraction are found to have characteristic induction and contraction times. This thesis presents the first molecular inhibition studies conducted using programmed subcellular release verifying that this technique can be used to study complex signaling pathways critical to cell motility. Molecular level dynamics of focal adhesion proteins and actin stress fibers provide some insight into the complexities associated with triggered cell detachment. In addition to subcellular release, the programmed release of alkanethiols provides a tool for to study the spatially and temporally controlled release of small molecules or particles from individually addressable gold electrodes. Here we report on experiments which determine the dynamics of programmed release using fluorophore

  17. Geomechanics of bedded salt

    International Nuclear Information System (INIS)

    Serata, S.; Milnor, S.W.

    1979-01-01

    Creep data from the literature search is reinterpreted by SGI, resulting in a better understanding of the temperature and stress state dependence of the octahedral creep rate and the octahedral shear strength. The concept of a transition strength between the elastic and the plastic states is in agreement with the data. The elastic and rheological properties of salt are described, and a set of constitutive equations is presented. The dependence of material properties on parameters such as temperature is considered. Findings on the permeability of salt are summarized, and the in-situ behavior of openings in bedded salt is described based on extensive engineering experience. A stress measuring system utilizing a finite element computer code is discussed. Geological factors affecting the stability of salt openings are considered, and the Stress Control Technique for designing stable openings in bedded salt formations is explained

  18. [Salt and cancer].

    Science.gov (United States)

    Strnad, Marija

    2010-05-01

    Besides cardiovascular disease, a high salt intake causes other adverse health effects, i.e., gastric and some other cancers, obesity (risk factor for many cancer sites), Meniere's disease, worsening of renal disease, triggering an asthma attack, osteoporosis, exacerbation of fluid retention, renal calculi, etc. Diets containing high amounts of food preserved by salting and pickling are associated with an increased risk of cancers of the stomach, nose and throat. Because gastric cancer is still the most common cancer in some countries (especially in Japan), its prevention is one of the most important aspects of cancer control strategy. Observations among Japanese immigrants in the U.S.A. and Brazil based on the geographic differences, the trend in cancer incidence with time, and change in the incidence patterns indicate that gastric cancer is closely associated with dietary factors such as the intake of salt and salted food. The findings of many epidemiological studies suggest that high dietary salt intake is a significant risk factor for gastric cancer and this association was found to be strong in the presence of Helicobacter (H.) pylori infection with atrophic gastritis. A high-salt intake strips the lining of the stomach and may make infection with H. pylori more likely or may exacerbate the infection. Salting, pickling and smoking are traditionally popular ways of preparing food in Japan and some parts of Asia. In addition to salt intake, cigarette smoking and low consumption of fruit and vegetables increase the risk of stomach cancer. However, it is not known whether it is specifically the salt in these foods or a combination of salt and other chemicals that can cause cancer. One study identified a mutagen in nitrite-treated Japanese salted fish, and chemical structure of this mutagen suggests that it is derived from methionine and that salt and nitrite are precursors for its formation. Working under conditions of heat stress greatly increased the workers

  19. Resedimented salt deposits

    Energy Technology Data Exchange (ETDEWEB)

    Slaczka, A.; Kolasa, K. (Jagiellonian Univ., Krakow (Poland))

    1988-08-01

    Carparthian foredeep's Wieliczka salt mine, unique gravity deposits were lately distinguished. They are mainly built of salt particles and blocks with a small admixture of fragments of Miocene marls and Carpathian rocks, deposited on precipitated salt. The pattern of sediment distribution is similar to a submarine fan. Gravels are dominant in the upper part and sands in lower levels, creating a series of lobes. Coarse-grained deposits are represented by disorganized, self-supported conglomerates passing into matrix-supported ones, locally with gradation, and pebbly sandstones consisting of salt grains and scattered boulder-size clasts. The latter may show in the upper part of a single bed as indistinct cross-bedding and parallel lamination. These sediments are interpreted as debris-flow and high-density turbidity current deposits. Salt sandstones (saltstones) which build a lower part of the fan often show Bouma sequences and are interpreted as turbidity-current deposits. The fan deposits are covered by a thick series of debrites (olistostromes) which consist of clay matrix with salt grains and boulders. The latter as represented by huge (up to 100,000 m{sup 3}) salt blocks, fragments of Miocene marls and Carpathian rocks. These salt debrites represent slumps and debris-flow deposits. The material for resedimented deposits was derived from the southern part of the salt basin and from the adjacent, advancing Carpathian orogen. The authors believe the distinct coarsening-upward sequence of the series is the result of progressive intensification of tectonic movements with paroxysm during the sedimentation of salt debrites (about 15 Ma).

  20. Water purification using organic salts

    Science.gov (United States)

    Currier, Robert P.

    2004-11-23

    Water purification using organic salts. Feed water is mixed with at least one organic salt at a temperature sufficiently low to form organic salt hydrate crystals and brine. The crystals are separated from the brine, rinsed, and melted to form an aqueous solution of organic salt. Some of the water is removed from the aqueous organic salt solution. The purified water is collected, and the remaining more concentrated aqueous organic salt solution is reused.

  1. Slab detachment under the Eastern Alps seen by seismic anisotropy.

    Science.gov (United States)

    Qorbani, Ehsan; Bianchi, Irene; Bokelmann, Götz

    2015-01-01

    We analyze seismic anisotropy for the Eastern Alpine region by inspecting shear-wave splitting from SKS and SKKS phases. The Eastern Alpine region is characterized by a breakdown of the clear mountain-chain-parallel fast orientation pattern that has been previously documented for the Western Alps and for the western part of the Eastern Alps. The main interest of this paper is a more detailed analysis of the anisotropic character of the Eastern Alps, and the transition to the Carpathian-Pannonian region. SK(K)S splitting measurements reveal a rather remarkable lateral change in the anisotropy pattern from the west to the east of the Eastern Alps with a transition area at about 12°E. We also model the backazimuthal variation of the measurements by a vertical change of anisotropy. We find that the eastern part of the study area is characterized by the presence of two layers of anisotropy, where the deeper layer has characteristics similar to those of the Central Alps, in particular SW-NE fast orientations of anisotropic axes. We attribute the deeper layer to a detached slab from the European plate. Comparison with tomographic studies of the area indicates that the detached slab might possibly connect with the lithosphere that is still in place to the west of our study area, and may also connect with the slab graveyard to the East, at the depth of the upper mantle transition zone. On the other hand, the upper layer has NW-SE fast orientations coinciding with a low-velocity layer which is found above a more-or-less eastward dipping high-velocity body. The anisotropy of the upper layer shows large-scale NW-SE fast orientation, which is consistent with the presence of asthenospheric flow above the detached slab foundering into the deeper mantle.

  2. PERIPHERAL RETINAL DEGENERATIONS AND RHEGMATOGENOUS DETACHMENT IN PRIMARY CONGENITAL GLAUCOMA.

    Science.gov (United States)

    Gupta, Shikha; Gogia, Varun; Jose, Cijin; Chanana, Bhuvan; Bypareddy, Ravi; Kapoor, Kulwant Singh; Gupta, Viney

    2016-01-01

    To determine the prevalence of peripheral retinal degenerations (PRD) and rhegmatogenous retinal detachment in patients with primary congenital glaucoma (PCG). Records of all patients with PCG operated from year 2000 onwards were evaluated to look for the prevalence of rhegmatogenous retinal detachment. Of these, those children who were old enough to cooperate and had sufficient medial clarity were screened with an indirect ophthalmoscopy in a cross-sectional evaluation from 2010 to 2014. Peripheral retina was examined, and prevalence of PRD was estimated in this subset. For statistical purposes, only one eye of each patient was considered in this cross-sectional analysis. Of the 310 eyes (180 patients with PCG) operated from the year 2000 onwards, a rhegmatogenous retinal detachment was noted in 13 eyes (4%). Mean axial length of these eyes was 26.3 ± 3.2 mm (range, 19.8-34.7 mm). Among the eyes screened for PRD (n = 60), prevalence of pathologic PRD (lattices with/without atrophic holes and isolated holes/tears) was 15%. The average follow-up between glaucoma filtering surgery and the date of last examination was 8.55 ± 3.98 years (range, 5-20 years) in this subset. Mean axial length was significantly greater in eyes with pathologic PRD than in those without (28.1 ± 3.3 mm vs. 25.8 ± 2.6 mm; P = 0.01). For axial length ≥ 26 mm, the odds of having a pathologic PRD were 14.4 times more than those with axial length < 26 mm (P < 0.001; 95% confidence interval, 1.7-120.5). Prevalence of PRD among eyes with PCG is high. Peripheral retinal screening should be performed in eyes with PCG, especially those with axial lengths ≥ 26 mm.

  3. Total retinal detachment occurring after minor head trauma.

    Science.gov (United States)

    Mircea, Pienaru; Ramona, Serban; Mircea, Filip; Andrei, Filip

    2015-01-01

    The objective of this article is to present the case of a patient with a severe decrease of visual acuity that occurred after an apparently minor head injury. Following the investigations, the patient was diagnosed with rhegmatogenous retinal detachment that was triggered by a fall from the same level and which occurred on a background of lattice degeneration. In this case, a minor trauma caused a severe complication because the patient had a contributing factor for the complication. The patient was operated and the end result was satisfactory.

  4. Mobility improvement by detached solidification of CZT crystals

    Science.gov (United States)

    Gamal, G. A.; Abou Zied, M.; Ebnalwaled, A. A.

    2007-06-01

    The mobility of undoped CdZnTe (CZT) crystals grown by vertical Bridgman method is improved by growing crystals without wall contact. Among the different factors playing an important role for appearance of detached growth, we have chosen the freezing rate as an effective factor for investigation with other factors were held constant. After growing a set of samples we have measured the dislocation densities for the grown samples by Warren-Averbach method. Unique results were obtained when we compared the dislocation densities and mobility, together with the freezing rate. This work and the included relations are published for the first time.

  5. Mobility improvement by detached solidification of CZT crystals

    Energy Technology Data Exchange (ETDEWEB)

    Gamal, G.A. [Physics Department, Faculty of Science, South Valley University, Qena 83523 (Egypt); Abou Zied, M. [Physics Department, Faculty of Science, South Valley University, Qena 83523 (Egypt); Ebnalwaled, A.A. [Physics Department, Faculty of Science, South Valley University, Qena 83523 (Egypt)]. E-mail: Kh_ebnalwaled@yahoo.com

    2007-06-15

    The mobility of undoped CdZnTe (CZT) crystals grown by vertical Bridgman method is improved by growing crystals without wall contact. Among the different factors playing an important role for appearance of detached growth, we have chosen the freezing rate as an effective factor for investigation with other factors were held constant. After growing a set of samples we have measured the dislocation densities for the grown samples by Warren-Averbach method. Unique results were obtained when we compared the dislocation densities and mobility, together with the freezing rate. This work and the included relations are published for the first time.

  6. Gases in molten salts

    CERN Document Server

    Tomkins, RPT

    1991-01-01

    This volume contains tabulated collections and critical evaluations of original data for the solubility of gases in molten salts, gathered from chemical literature through to the end of 1989. Within the volume, material is arranged according to the individual gas. The gases include hydrogen halides, inert gases, oxygen, nitrogen, hydrogen, carbon dioxide, water vapor and halogens. The molten salts consist of single salts, binary mixtures and multicomponent systems. Included also, is a special section on the solubility of gases in molten silicate systems, focussing on slags and fluxes.

  7. Carbon distribution during plasma detachment triggered by edge magnetic island formation in LHD

    International Nuclear Information System (INIS)

    Dong, C.F.; Morita, S.; Kobayashi, M.; Oishi, T.; Goto, M.; Wang, E.H.; Huang, X.L.

    2013-01-01

    The detached plasma has been successfully achieved by applying the edge 1/1 magnetic island in Large Helical Device (LHD). Carbon, which is uniquely the dominant intrinsic impurity in general LHD discharges, is considered to be the main radiating species in the island-triggered detached plasma. The vertical profile of CIV measured from general discharges of LHD is characterized by a single edge intensity peak. In detached plasmas triggered by the edge magnetic island formation, however, the vertical profile of CIV shows a significant difference. Double edge peaks of CIV are found during the plasma detachment and the CIV radiation is also remarkably enhanced in the vicinity of X-point, whereas the vertical profile of CVI does not show any significant difference in both the attached and detached plasmas. In this proceeding the carbon distribution during the plasma detachment is presented and the results are discussed with edge magnetic field structure. (author)

  8. FACTORS ASSOCIATED WITH VISUAL OUTCOME AFTER MACULA-OFF RHEGMATOGENOUS RETINAL DETACHMENT SURGERY.

    Science.gov (United States)

    Park, Dae Hyun; Choi, Kyung Seek; Sun, Hae Jung; Lee, Sung Jin

    2018-01-01

    To evaluate preoperative factors influencing the visual outcome and postoperative factors associated with the changes in visual acuity, after reattachment surgery to treat macula-off rhegmatogenous retinal detachment. A total of 180 eyes of 180 patients who underwent reattachment surgery to treat macula-off rhegmatogenous retinal detachment, and who were followed up for more than 12 months, were reviewed retrospectively. Preoperative and postoperative characteristics, including optical coherence tomography findings, were comprehensively analyzed using univariate and multivariate models to evaluate preoperative factors influencing best-corrected visual acuity 12 months after macula-off rhegmatogenous retinal detachment surgery and postoperative factors associated with changes in best-corrected visual acuity after surgery. Preoperatively, the extent of detachment (P = 0.037), macula-off duration (P macula-off rhegmatogenous retinal detachment surgery were the extent of detachment, macula-off duration, and external limiting membrane integrity. Postoperatively, predictive factors were the outer retinal microstructures, particularly the photoreceptor outer segment layer.

  9. Influence of pre-salt topographic features on supra-salt deformation in Mediterranean basins: Geology vs. physical models

    Science.gov (United States)

    Ferrer, Oriol; Vidal-Royo, Oskar; Gratacós, Oscar; Roca, Eduard; Muñoz, Josep Anton; Esestime, Paolo; Rodriguez, Karyna; Yazmin Piragauta, Mary; Feliu, Nil

    2017-04-01

    The presence of a thick Messinian evaporite unit is a well known feature of the Mediterranean basins. This salt unit is composed of three sub-units (Lower, Mobile and Upper Units) in the Northwest Mediterranean. In contrast, in the Eastern Mediterranean it is characterized by a multilayered evaporite sequence. In both regions the salt acted as a detachment favoring the downslope gravitational failure of the overlying sediments in a thin-skinned deformation regime (e.g. Liguro-Provençal or Levant basins). As a result, these salt-bearing passive margins exhibit the classical three-domain structural zonation characterized by upslope extension, intermediate translation and downslope contraction. Nevertheless, the presence of pre-salt reliefs (e.g. irregularly eroded palaeotopography or volcanic edifices) is rather common in the translational domain of the Northwestern Mediterranean (e.g. Liguro-Provençal and West Corsica margins). In this scenario, pre-salt reliefs act as flow barriers and hinder salt drainage. When their summit lies close or above the top salt, these structures may partially or fully block salt flow. They also disrupt locally the structural zonation of the passive margin and constrain cover deformation. In contrast, in the Eastern Mediterranean the Eratosthenes seamount is characterized by a large scale submerged massif (ca. 120 km in size) that significantly influenced the structural evolution of the surrounding areas. This inherited relief acted as a buttress and deflected the Messinian salt flow constraining supra-salt deformation (e.g. Levant Basin and Nile margin). In addition, the geometry of the Eratosthenes seamount also restrained the structural style of the allochthonous salt that was expulsed during the development of the Cyprus subduction zone to the north. Using an experimental approach (sandbox models) and new analysis techniques, we investigate salt and supra-salt deformation in response to two different types of pre-salt relief: 1

  10. What Are Bath Salts?

    Science.gov (United States)

    ... bath salts can produce: feelings of joy increased social interaction increased sex drive paranoia nervousness hallucinations (see or ... and Addiction Drug Overdoses in Youth Viral Infections (HIV, Hepatitis) and Drug Use Real Questions from Real ...

  11. Cellular volume regulation and substrate stiffness modulate the detachment dynamics of adherent cells

    Science.gov (United States)

    Yang, Yuehua; Jiang, Hongyuan

    2018-03-01

    Quantitative characterizations of cell detachment are vital for understanding the fundamental mechanisms of cell adhesion. Experiments have found that cell detachment shows strong rate dependence, which is mostly attributed to the binding-unbinding kinetics of receptor-ligand bond. However, our recent study showed that the cellular volume regulation can significantly regulate the dynamics of adherent cell and cell detachment. How this cellular volume regulation contributes to the rate dependence of cell detachment remains elusive. Here, we systematically study the role of cellular volume regulation in the rate dependence of cell detachment by investigating the cell detachments of nonspecific adhesion and specific adhesion. We find that the cellular volume regulation and the bond kinetics dominate the rate dependence of cell detachment at different time scales. We further test the validity of the traditional Johnson-Kendall-Roberts (JKR) contact model and the detachment model developed by Wyart and Gennes et al (W-G model). When the cell volume is changeable, the JKR model is not appropriate for both the detachments of convex cells and concave cells. The W-G model is valid for the detachment of convex cells but is no longer applicable for the detachment of concave cells. Finally, we show that the rupture force of adherent cells is also highly sensitive to substrate stiffness, since an increase in substrate stiffness will lead to more associated bonds. These findings can provide insight into the critical role of cell volume in cell detachment and might have profound implications for other adhesion-related physiological processes.

  12. Detached eddy simulation of unsteady cavitation and pressure fluctuation around 3-D NACA66 hydrofoil

    Directory of Open Access Journals (Sweden)

    Zhang De-Sheng

    2015-01-01

    Full Text Available The unsteady cavitating flow and pressure fluctuation around the 3-D NACA66 hydrofoil were simulated and validated based on detached eddy simulation turbulence model and a homogeneous cavitation model. Numerical results show that detached eddy simulation can predict the evolution of cavity inception, sheet cavitation growth, cloud cavitation shedding, and breakup, as well as the pressure fluctuation on the surface of hydrofoil. The sheet cavitation growth, detachment, cloud cavitation shedding are responsible for the features of the pressure fluctuation.

  13. Proteomic Analysis of the Vitreous following Experimental Retinal Detachment in Rabbits

    DEFF Research Database (Denmark)

    Mandal, Nakul; Lewis, Geoffrey P.; Fisher, Steven K.

    2015-01-01

    of the vitreous following experimental retinal detachment using a comparative proteomic based approach. Materials and Methods. Retinal detachment was created in the right eyes of six New Zealand red pigmented rabbits. Sham surgery was undertaken in five other rabbits that were used as controls. After seven days......, and α-1-antiproteinase F. Conclusions. Proteomic investigation of the rabbit vitreous has identified a set of proteins that help further our understanding of the pathogenesis of rhegmatogenous retinal detachment and its complications....

  14. Enzymatic detachment of therapeutic mesenchymal stromal cells grown on glass carriers in a bioreactor.

    Science.gov (United States)

    Salzig, Denise; Schmiermund, Alexandra; P Grace, Pablo; Elseberg, Christiane; Weber, Christian; Czermak, Peter

    2013-01-01

    Cell therapies require the in vitro expansion of adherent cells such as mesenchymal stromal cells (hMSCs) in bioreactor systems or other culture environments, followed by cell harvest. As hMSCs are strictly adherent cells, cell harvest requires cell detachment. The use of hMSCs for cell therapy requires GMP production in accordance with the guidelines for advanced therapeutic medical products. Therefore, several GMP-conform available proteolytic enzymes were investigated for their ability to promote hMSC detachment. An allogeneic hMSC cell line (hMSC-TERT) that is used in clinical trials in the form of alginate cell capsules was chosen as a model. This study investigated the influence of several factors on the outcome of proteolytic hMSC-TERT detachment. Therefore, hMSC-TERT detachment was analyzed in different cultivation systems (static, dynamic) and in combination with further cell processing including encapsulation. Only two of the commercially available enzymes (AccutaseTM, TrypZeanTM) that fulfill all process requirements (commercial availability, cost, GMP conditions during manufacturing and non-animal origin) are found to be generally suitable for detaching hMSC-TERT. Combining cell detachment with encapsulation demonstrated a high impact of the experimental set up on cell damage. It was preferable to reduce the temperature during detachment and limit the detachment time to a maximum of 20 minutes. Cell detachment in static systems was not comparable with detachment in dynamic systems. Detachment yields in dynamic systems were lower and cell damage was higher for the same experimental conditions. Finally, only TrypZeanTM seemed to be suitable for the detachment of hMSC-TERT from dynamic reactor systems.

  15. Glaucoma associated with the management of rhegmatogenous retinal detachment

    Directory of Open Access Journals (Sweden)

    Mangouritsas G

    2013-04-01

    Full Text Available George Mangouritsas, Spyridon Mourtzoukos, Dimitra M Portaliou, Vassilios I Georgopoulos, Anastasia Dimopoulou, Elias Feretis Eye Clinic, General Hospital "Hellenic Red Cross", Athens, Greece Abstract: Transient or permanent elevation of intraocular pressure (IOP is a common complication following vitreoretinal surgery. Usually secondary glaucoma, which develops after scleral buckling procedures, or pars plana vitrectomy for repair of rhegmatogenous retinal detachment, is of multifactorial origin. It is essential, for appropriate management, to detect the cause of outflow obstruction. An exacerbation of preexisting open-angle glaucoma or a steroid-induced elevation of IOP should also be considered. Scleral buckling may be complicated by congestion and anterior rotation of the ciliary body resulting in secondary angle closure, which can usually resolve with medical therapy. The use of intravitreal gases may also induce secondary angle-closure with or without pupillary block. Aspiration of a quantity of the intraocular gas may be indicated. Secondary glaucoma can also develop after intravitreal injection of silicone oil due to pupillary block, inflammation, synechial angle closure, or migration of emulsified silicone oil in the anterior chamber and obstruction of the aqueous outflow pathway. In most eyes medical therapy is successful in controlling IOP; however, silicone oil removal with or without concurrent glaucoma surgery may also be required. Diode laser transscleral cyclophotocoagulation and glaucoma drainage devices constitute useful treatment modalities for long-term IOP control. Cooperation between vitreoretinal and glaucoma specialists is necessary to achieve successful management. Keywords: retinal detachment, intraocular pressure elevation, glaucoma, vitrectomy, intravitreal gas, silicone oil

  16. Electron detachment from negative ions in a short laser pulse

    International Nuclear Information System (INIS)

    Shearer, S. F. C.; Smyth, M. C.; Gribakin, G. F.

    2011-01-01

    We present an efficient and accurate method to study electron detachment from negative ions by a few-cycle linearly polarized laser pulse. The adiabatic saddle-point method of Gribakin and Kuchiev [Phys. Rev. A 55, 3760 (1997)] is adapted to calculate the transition amplitude for a short laser pulse. Its application to a pulse with N optical cycles produces 2(N+1) saddle points in complex time, which form a characteristic 'smile.' Numerical calculations are performed for H - in a 5-cycle pulse with frequency 0.0043 a.u. and intensities of 10 10 , 5x10 10 , and 10 11 W/cm 2 , and for various carrier-envelope phases. We determine the spectrum of the photoelectrons as a function of both energy and emission angle, as well as the angle-integrated energy spectra and total detachment probabilities. Our calculations show that the dominant contribution to the transition amplitude is given by 5-6 central saddle points, which correspond to the strongest part of the pulse. We examine the dependence of the photoelectron angular distributions on the carrier-envelope phase and show that measuring such distributions can provide a way of determining this phase.

  17. Macula-Sparing rhegmatogenous retinal detachment: Is emergent surgery necessary?

    Directory of Open Access Journals (Sweden)

    Sasan Mahmoudi

    2016-01-01

    Full Text Available The status of the macula is a significant factor in determining final visual outcomes in rhegmatogenous retinal detachment (RRD and should be considered in the timing of surgical repair. Several studies have shown that macula-involving RRDs attain similar visual and anatomic outcomes when surgery is performed within seven days as compared to emergent surgery (within 24 hours. In contrast, surgery prior to macular detachment in macula-sparing RRDs generally yields the best visual outcomes. In the case of macula-sparing RRDs, it is not clear how long the macula may remain attached, therefore, standard practice dictates emergent surgery. Timing of presentation, examination findings, case complexity, co-existing medical conditions, surgeon expertise, and timing and quality of access to operating facilities and staff, however, should all be considered in determining whether a macula-sparing RRD requires immediate intervention or if equivalent visual and possibly better overall outcomes can be achieved with scheduled surgery within an appropriate time frame.

  18. Vitreous Microparticle Shedding in Retinal Detachment: A Prospective Comparative Study.

    Science.gov (United States)

    Tumahai, Perle; Saas, Philippe; Ricouard, Fanny; Biichlé, Sabéha; Puyraveau, Marc; Laheurte, Caroline; Delbosc, Bernard; Saleh, Maher

    2016-01-01

    Microparticles (MPs) are membrane-derived vesicles measuring less than 1 μm in diameter. They are shed from nearly every activated or preapoptotic cell and may exhibit biologic activities in inflammation or apoptosis settings. The main purpose of this study was to determine whether MP shedding was higher in the vitreous of patients with retinal detachment (RD). This was a prospective, comparative study. Levels of vitreous MPs (including phosphatidylserine [PS]-expressing MPs, photoreceptor cell-derived MPs, and photoreceptor cell-derived MPs expressing PS) and soluble proinflammatory factors (i.e., monocyte chemoattractant protein-1, intercellular adhesion molecule-1, and IL-6) were analyzed by flow cytometry. Samples were obtained from 49 eyes undergoing RD surgery and 41 control eyes. Vitreous levels of all the MPs studied were significantly increased in the RD group. Vitreous MP levels were correlated with levels of at least one proinflammatory factor depending on MP subsets. Concerning clinical parameters, vitreous PS-expressing MP and PS-expressing photoreceptor cell-derived MP levels were higher depending on the duration of RD at surgery, the detached retina surface, and the macula status and were found more sensitive than proinflammatory factors only for the duration of RD at surgery. Vitreous concentrations of MPs (mainly derived from photoreceptor cells) are higher after rhegmatogenous RD and found to be correlated with soluble proinflammatory factors.

  19. In vitro biomechanical modulation--retinal detachment in a box.

    Science.gov (United States)

    Ghosh, Fredrik; Arnér, Karin; Taylor, Linnéa

    2016-03-01

    To illustrate the importance of biomechanical impact on tissue health within the central nervous system (CNS), we herein describe an in vitro model of rhegmatogenous retinal detachment (RRD) in which disruption and restoration of physical tissue support can be studied in isolation. Adult retinal porcine explants were kept in culture for 3 or 12 hours without any tissue support, simulating clinical RRD, after which they were either maintained in this state or reattached to the culture membrane for an additional 48 hours. In vitro detachment resulted in gliosis and severe progressive loss of retinal neurons. In contrast, if the explant was reattached, gliosis and overall cell death was attenuated, ganglion cell death was arrested, and the number of transducin-expressing cone photoreceptors increased. These results support the hypothesis that removal of the elastic retina from its normal physical environment results in degenerative damage, and, if restored, rescues retinal neurons. Our study reinforces the notion of a strong relationship between the biomechanical environment and homeostasis within the retina, which has significant bearing on pathologic events related to RRD, and may also have impact on other regions within the CNS under biomechanical influence.

  20. Two Cases of Rhegmatogenous Retinal Detachment Associated with Asteroid Hyalosis

    Directory of Open Access Journals (Sweden)

    Yoshitaka Okuda

    2018-01-01

    Full Text Available Background: To report two cases of rhegmatogenous retinal detachment (RRD associated with asteroid hyalosis (AH. Case Presentation: Two patients presented with RRD originating from a flap tear. Case 1 involved a 62-year-old male who was found to have bullous RRD in his left eye originating from a flap tear. During vitreous surgery, a thick vitreous cortex was found to have strongly adhered to the entire retinal surface, from the center to the periphery. A bimanual method was then used in conjunction with the vitrectomy to create an artificial posterior vitreous detachment. After surgery, the retina was successfully reattached, and his corrected visual acuity (VA improved. Case 2 involved a 70-year-old male who was found to have localized RRD in his left eye originating from a flap tear. During vitreous surgery, a thick vitreous cortex was found to have strongly adhered to the entire retinal surface. After surgery, the retina was successfully reattached, and his corrected VA improved. Conclusions: RRD associated with AH presents with stronger vitreoretinal adhesion compared to typical RRD, thus requiring a more complicated surgical technique to properly treat the patient.

  1. Anatomical success in patients after retinectomy for complex retinal detachment

    International Nuclear Information System (INIS)

    Mukhtar, A.; Ishaq, M.; Islam, Q.U.

    2015-01-01

    To evaluate the efficacy of primary and redo retinectomy in eyes with complex retinal detachment. Study Design: Quasi-experimental study. Place and Duration of Study: Armed Forces Institute of Ophthalmology Rawalpindi from Jan 2012 to June 2013. Patients and Methods: Fifty eight eyes (patients) underwent relaxing retinectomies for complex retinal detachment with proliferative vitreoretinopathy or intrinsic retinal shortening. Operative technique included pars plana vitrectomy, proliferative vitreoretinopathy management, use of intraoperative perfluorocarbon liquid, retinectomy, endolaser and intraocular temponade. The main outcome was anatomic success, defined as complete retinal reattachment at four months follow up. Eighteen eyes out of the same primary group underwent second retinectomy because of anatomical failure. Results: Mean age of study population was 53.78 ± 15.11 years, 56.9% of patients were male(s). Anatomic success rate after 1st retinectomy was achieved in 68.96% (40 eyes out of 58). In eighteen eyes that underwent 2nd retinectomy, anatomic success rate was 72.22% (13 eyes out of 18). Overall success rate was 91.3% (53 eyes out of 58) in our study. Conclusions: Relaxing retinectomies for retinal shortening can improve the anatomical success rate in patients with complex RD. (author)

  2. Detachment of particulate iron sulfide during shale-water interaction

    Science.gov (United States)

    Emmanuel, S.; Kreisserman, Y.

    2017-12-01

    Hydraulic fracturing, a commonly used technique to extract oil and gas from shales, is controversial in part because of the threat it poses to water resources. The technique involves the injection into the subsurface of large amounts of fluid, which can become contaminated by fluid-rock interaction. The dissolution of pyrite is thought to be a primary pathway for the contamination of fracturing fluids with toxic elements, such as arsenic and lead. In this study, we use direct observations with atomic force microscopy to show that the dissolution of carbonate minerals in Eagle Ford shale leads to the physical detachment of embedded pyrite grains. To simulate the way fluid interacts with a fractured shale surface, we also reacted rock samples in a flow-through cell, and used environmental scanning electron microscopy to compare the surfaces before and after interaction with water. Crucially, our results show that the flux of particulate iron sulfide into the fluid may be orders of magnitude higher than the flux of pyrite from chemical dissolution. This result suggests that mechanical detachment of pyrite grains could be the dominant mode by which arsenic and other inorganic elements are mobilized in the subsurface. Thus, during hydraulic fracturing operations and in groundwater systems containing pyrite, the transport of many toxic species may be controlled by the transport of colloidal iron sulfide particles.

  3. Mass transport in bedded salt and salt interbeds

    International Nuclear Information System (INIS)

    Hwang, Y.; Pigford, T.H.; Chambre, P.L.; Lee, W.W.L.

    1989-08-01

    Salt is the proposed host rock for geologic repositories of nuclear waste in several nations because it is nearly dry and probably impermeable. Although experiments and experience at potential salt sites indicate that salt may contain brine, the low porosity, creep, and permeability of salt make it still a good choice for geologic isolation. In this paper we summarize several mass-transfer and transport analyses of salt repositories. The mathematical details are given in our technical reports

  4. Molten salt reactor type

    International Nuclear Information System (INIS)

    1977-01-01

    This document is one of the three parts of a first volume devoted to the compilations of American data on the molten salt reactor concept. Emphasize is put essentially on the fuel salt of the primary circuit inside which fission reactions occur. The reasons why the (LiF-BeF 2 -ThF 4 -UF 4 ) salt was chosen for the M.S.B.R. concept are examined; the physical, physicochemical and chemical properties of this salt are discussed with its interactions with the structural materials and its evolution in time. An important part of this volume is devoted to the continuous reprocessing of the active salt, the project designers having deemed advisable to take advantage at best from the availability of a continuous purification, in a thermal breeding. The problem of tritium formation and distribution inside the reactor is also envisaged and the fundamentals of the chemistry of the secondary coolant salt are given. The solutions proposed are: the hydrogen scavenging of the primary circuit, a reduction in metal permeability by an oxyde layer deposition on the side in contact with the vapor, and tritium absorption through an isotope exchange with the hydroxifluoroborate [fr

  5. Not salt taste perception but self-reported salt eating habit predicts actual salt intake.

    Science.gov (United States)

    Lee, Hajeong; Cho, Hyun-Jeong; Bae, Eunjin; Kim, Yong Chul; Kim, Suhnggwon; Chin, Ho Jun

    2014-09-01

    Excessive dietary salt intake is related to cardiovascular morbidity and mortality. Although dietary salt restriction is essential, it is difficult to achieve because of salt palatability. However, the association between salt perception or salt eating habit and actual salt intake remains uncertain. In this study, we recruited 74 healthy young individuals. We investigated their salt-eating habits by questionnaire and salt taste threshold through a rating scale that used serial dilution of a sodium chloride solution. Predicted 24-hr urinary salt excretions using Kawasaki's and Tanaka's equations estimated dietary salt intake. Participants' mean age was 35 yr, and 59.5% were male. Salt sense threshold did not show any relationship with actual salt intake and a salt-eating habit. However, those eating "salty" foods showed higher blood pressure (P for trend=0.048) and higher body mass index (BMI; P for trend=0.043). Moreover, a salty eating habit was a significant predictor for actual salt intake (regression coefficient [β] for Kawasaki's equation 1.35, 95% confidence interval [CI] 10-2.69, P=0.048; β for Tanaka's equation 0.66, 95% CI 0.01-1.31, P=0.047). In conclusion, a self-reported salt-eating habit, not salt taste threshold predicts actual salt intake.

  6. Vitrectomy for circumscribed choroidal hemangioma with exudative retinal detachment refractory to transpupillary thermotherapy

    Directory of Open Access Journals (Sweden)

    Shukla Dhananjay

    2007-01-01

    Full Text Available We report successful surgical management of a circumscribed choroidal hemangioma with exudative retinal detachment refractory to transpupillary thermotherapy (TTT. A 33-year-old man with symptomatic serous macular detachment in the left eye (Snellen acuity: 20/200 secondary to a paramacular choroidal hemangioma was treated with TTT. The nonresponsive detachment was subsequently managed by vitrectomy, endophotocoagulation and silicon-oil tamponade. It resulted in complete resolution of the tumor and the detachment. Silicon oil was removed at four months. Visual acuity improved to 20/80 by the last follow-up visit at 10 months without any recurrence.

  7. Phakic retinal detachment associated with atrophic hole of lattice degeneration of the retina.

    Science.gov (United States)

    Murakami-Nagasako, F; Ohba, N

    1983-01-01

    Forty patients with phakic nontraumatic retinal detachment caused by atrophic retinal hole of lattice degeneration were reviewed. The condition was characterized by insidious, slowly developing shallow detachment, with frequent formation of demarcation lines. Often, the patients did not recognize their visual problems until the detachment had extended to the macular region. Young patients under 40 years of age were more common than older patients. Myopic refractive errors were frequently associated. The results of surgical repair were favorable. The risk of retinal detachment in lattice degeneration with atrophic holes was estimated to be about 1 in 90 patients, and prophylactic treatment for this common anomaly is not readily recommended.

  8. Evaluation of the Strategy-Structure Fit of Space and Missile Systems Center Detachment 11

    National Research Council Canada - National Science Library

    Gates, Tommy

    2001-01-01

    ... (SBlRSl, and the Global Positioning System (GPS). The Detachment performs operational software maintenance, satellite systems engineering, space testing and evaluation, and technology master planning...

  9. Adhesion mechanism of a gecko-inspired oblique structure with an adhesive tip for asymmetric detachment

    International Nuclear Information System (INIS)

    Sekiguchi, Yu; Sato, Chiaki; Takahashi, Kunio

    2015-01-01

    An adhesion model of an oblique structure with an adhesive tip is proposed by considering a limiting stress for adhesion to describe the detachment mechanism of gecko foot hairs. When a force is applied to the root of the oblique structure, normal and shear stresses are generated at contact and the adhesive tip is detached from the surface when reaching the limiting stress. An adhesion criterion that considers both the normal and shear stresses is introduced, and the asymmetric detachment of the oblique structure is theoretically investigated. In addition, oblique beam array structures are manufactured, and an inclination effect of the structure on the asymmetric detachment is experimentally verified. (paper)

  10. Cooperativity of complex salt bridges

    OpenAIRE

    Gvritishvili, Anzor G.; Gribenko, Alexey V.; Makhatadze, George I.

    2008-01-01

    The energetic contribution of complex salt bridges, in which one charged residue (anchor residue) forms salt bridges with two or more residues simultaneously, has been suggested to have importance for protein stability. Detailed analysis of the net energetics of complex salt bridge formation using double- and triple-mutant cycle analysis revealed conflicting results. In two cases, it was shown that complex salt bridge formation is cooperative, i.e., the net strength of the complex salt bridge...

  11. Effect of Low Salt Diet on Insulin Resistance in Salt Sensitive versus Salt Resistant Hypertension

    Science.gov (United States)

    Garg, Rajesh; Sun, Bei; Williams, Jonathan

    2014-01-01

    Accumulating evidence shows an increase in insulin resistance on salt restriction. We compared the effect of low salt diet on insulin resistance in salt sensitive versus salt resistant hypertensive subjects. We also evaluated the relationship between salt sensitivity of blood pressure and salt sensitivity of insulin resistance in a multivariate regression model. Studies were conducted after one week of high salt (200 mmol/day Na) and one week of low salt (10 mmol/day Na) diet. Salt sensitivity was defined as the fall in systolic blood pressure >15mmHg on low salt diet. The study includes 389 subjects (44% Females, 16% Blacks, BMI 28.5±4.2 Kg/m2). As expected, blood pressure was lower on low salt (129±16/78±9 mmHg) as compared to high salt diet (145±18/86±10 mmHg). Fasting plasma glucose, insulin and HOMA were higher on low salt diet (95.4±19.4 mg/dl, 10.8±7.3 mIU/L and 2.6±1.9) as compared to high salt diet (90.6±10.8 mg/dl, 9.4±5.8 mIU/L and 2.1±1.4) (p salt sensitive (N=193) versus salt resistant (N=196) subjects on either diet. Increase in HOMA on low salt diet was 0.5±1.4 in salt sensitive and 0.4±1.5 in salt resistant subjects (p=NS). On multivariate regression analysis, change in systolic blood pressure was not associated with change in HOMA after including age, BMI, sex, change in serum and urine aldosterone and cortisol into the model. We conclude that the increase in insulin resistance on low salt diet is not affected by salt sensitivity of blood pressure. PMID:25185125

  12. An Assessment of Molten Metal Detachment Hazards During Electron Beam Welding in Space

    Science.gov (United States)

    Fragomeni, James M.; Nunes, Arthur C., Jr.

    1998-01-01

    The safety issue has been raised with regards to potential molten metal detachments from the weld pool and cold filler wire during electron beam welding in space. This investigation was undertaken to evaluate if molten metal could detach and come in contact with astronauts and burn through the fabric of the astronauts' Extravehicular Mobility Unit (EMU) during electron beam welding in space. Molten metal detachments from either the weld/cut substrate or weld wire could present harm to a astronaut if the detachment was to burn through the fabric of the EMU. Theoretical models were developed to predict the possibility and size of the molten metal detachment hazards during the electron beam welding exercises at Low Earth Orbit (LEO). The primary molten metal detachment concerns were those cases of molten metal separation from the metal surface due to metal cutting, weld pool splashing, entrainment and release of molten metal due to filler wire snap-out from the weld puddle, and molten metal accumulation and release from the end of the weld wire. Some possible ways of obtaining molten metal drop detachments would include an impulse force, or bump, to the weld sample, cut surface, or filler wire. Theoretical models were developed for these detachment concerns from principles of impact and kinetic energies, surface tension, drop geometry, surface energies, and particle dynamics. The surface tension represents the force opposing the liquid metal drop from detaching whereas the weight of the liquid metal droplet represents a force that is tending to detach the molten metal drop. Theoretical calculations have indicated that only a small amount of energy is required to detach a liquid metal drop; however, much of the energy of an impact is absorbed in the sample or weld plate before it reaches the metal drop on the cut edge or surface. The tendency for detachment is directly proportional to the weld pool radius and metal density and inversely proportional to the surface

  13. Carbonate pseudotachylite? from a Miocene extensional detachment, W. Cyclades, Greece.

    Science.gov (United States)

    Rice, A. Hugh N.; Grasemann, Bernhard

    2016-04-01

    Most pseudotachylites, both impact- and fault-related, occur in silicate-rich rocks, typically with 'granitoid' compositions. Examples of melting in carbonate rocks, excluding magmatic sources, are restricted to impact-events, except for a carbonate pseudotachylite in the Canalone Fault, S. Italy (Viganò et al. 2011). Another potential example of carbonate pseudotachylite, shown here, comes from the Miocene-aged W. Cycladic Detachment System, in Greece. Top-SSE ductile to brittle movement on this detachment, with a maximum displacement estimated at tens of kilometers, exhumed of HP-rocks. The carbonate pseudotachylite occurs within an 43 mm thick), consists of dark (hematitic) red, ultra-fine grained unlayered carbonate with up to 40x10 mm rather rounded clasts of earlier generations of cataclasite, many with a quartzite composition. These clasts are fractured and partially separated, with a fine red carbonate matrix. No layering of the matrix or clasts is apparent. The clasts become finer and more abundant towards the boundary with Layer B. Layers B and D (~57 & ~20 mm thick) dominantly comprises protocataclasite with greyish quartz fragments separated by a carbonate matrix along narrow fractures. Zone C and E (~23 m & >15 mm thick) comprise pale pink carbonate-dominated rocks with abundant clasts (+/- quartz fragments) of earlier cataclasite generations. These elongate clasts lie parallel to the overall banding, which is parallel to the ultramylonitic foliation (detachment surface). Smaller clasts are markedly more rounded and comprise carbonate and quartzite material and may have darker (?reaction) rims. No layering is seen in the pale pink groundmass although this is present in some elongate clasts. All layer boundaries are irregular and no principle slip surfaces have been seen. Injection veins from 1 to 9 mm wide and up to at least 100 mm long derive from the central layer (C), cutting the overall layering at a high angle and branching in several places

  14. Post-operative hospitalization in retinal detachment correlation to recurrences

    Directory of Open Access Journals (Sweden)

    Enzo Maria Vingolo

    2013-12-01

    Full Text Available PURPOSE: To evaluate relationships between the incidence of re-detachment and postoperative days of hospitalization in patients with diagnosis of retinal detachment (RD who underwent surgery either through ab-externo approach (scleral buckling and encircling or ab-interno approach (vitrectomy and oil-gas tamponade. METHODS: This retrospective study included 268 patients (268 eyes with diagnosis of primary RD: 127 males (47% and 141 (53% females, mean age of 64.1 ± 17.3 years. 46 patients (17% underwent a surgical ab-externo approach (group A, while 222 patients (83% underwent an ab-interno surgical approach. Each RD was graded according to the "Retinal detachment grading system of Royal College of Ophthalmologists" and treated within 5 days after diagnosis. The redetachment (RT related to a surgical failure was considered within 30 days after first operation. RESULTS: In the group 1 without night hospitalization (day surgery global RT rate was 3.5% (4.17% for ab-interno technique and 0% for ab-externo techniques. In the group 2 with one day of hospitalization global RT rate was 1.33% (1.49% for ab-interno technique and 0% for ab-externo techniques. In the group 3 with 2 days of hospitalization global RT rate was 3.80% (4.62% for ab-interno techniques and 0% for ab-externo techniques. In the group 4 with 3 or more days of hospitalization global RT rate was 12.28% (14.29% for ab-interno techniques for 6.67% ab-externo techniques. The incidence of RT in group 1, day surgery, is comparable to the other groups and it is less compared to group 4 (3 or more days of hospitalization. CONCLUSIONS: The incidence of retinal redetachment (RRD is not increased in day surgery mode. These data support outpatient management of RD patients to reduce medical cost and problems related to the hospitalization. Further studies are needed for patients' security.

  15. Slip on serpentine detachments at magma-poor margins

    Science.gov (United States)

    Reston, Timothy; Lymer, Gael; Cresswell, Derren; Stevenson, Carl; Bull, Jonathan; Sawyer, Dale; Morgan, Julia; Galicia 3D working Group

    2017-04-01

    At magma-poor margins, the structures formed during rifting are not obscured by thick lavas, allowing detailed analysis of the tectonics of rifting and breakup. At most of these margins, the mantle beneath the thin crust has unusually low velocities, interpreted as a consequence of serpentinization following the embrittlement of the crust during rifting; models for the onset of serpentinization predict the thicknesses of crust that are observed at the landward limit of the serpentinized mantle. At a handful of margins the top of the serpentinized mantle appears to have acted as a detachment or decollement: faults that bound the overlying crustal blocks root on a bright reflection at the base of these blocks. Examples include the P reflection west of Ireland, the H reflection west of northern Portugal, and the S reflector west of Galicia. Corrugations observed on a 3D volume collected in 2013 above the S reflector strongly support its interpretation as a slip surface. A remaining question is whether slip on these "serpentine detachments" occurred at low-angle or not: for typical friction coefficients of 0.7, normal faults should lock-up and be replaced by steeper faults once they have rotated to perhaps 35°, an observation consistent with earthquake data. This angle can be reduced to 20-25° if the fault zone is composed of weak minerals such as serpentine. One possibility is that the detachment is actually composed of segments of faults that were active sequentially in a rolling hinge model. Beneath the centre of the Porcupine basin, the P reflection is sub-horizontal but its western continuation dips beneath the Porcupine bank at 20-25°, consistent with slip on serpentine-weakened rolling hinge system. West of Galicia, based on the geometrical relationships between late synrift wedges and their bounding faults which root on S, S has been interpreted to have slipped at angles below 20-25°. However, a 3D dataset collected over S in 2013 provides the opportunity

  16. Great Salt Lake, Utah

    Science.gov (United States)

    Stephens, Doyle W.; Gardner, Joe F.

    1999-01-01

    This document is intended as a source of general information and facts about Great Salt Lake, Utah. This U.S. Geological Survey information sheet answers frequently asked questions about Great Salt Lake. Topics include: History, salinity, brine shrimp, brine flies, migratory birds, and recreation. Great Salt Lake, the shrunken remnant of prehistoric Lake Bonneville, has no outlet. Dissolved salts accumulate in the lake by evaporation. Salinity south of the causeway has ranged from 6 percent to 27 percent over a period of 22 years (2 to 7 times saltier than the ocean). The high salinity supports a mineral industry that extracts about 2 million tons of salt from the lake each year. The aquatic ecosystem consists of more than 30 species of organisms. Harvest of its best-known species, the brine shrimp, annually supplies millions of pounds of food for the aquaculture industry worldwide. The lake is used extensively by millions of migratory and nesting birds and is a place of solitude for people. All this occurs in a lake that is located at the bottom of a 35,000-square-mile drainage basin that has a human population of more than 1.5 million.

  17. Fundamental Properties of Salts

    Energy Technology Data Exchange (ETDEWEB)

    Toni Y Gutknecht; Guy L Fredrickson

    2012-11-01

    Thermal properties of molten salt systems are of interest to electrorefining operations, pertaining to both the Fuel Cycle Research & Development Program (FCR&D) and Spent Fuel Treatment Mission, currently being pursued by the Department of Energy (DOE). The phase stability of molten salts in an electrorefiner may be adversely impacted by the build-up of fission products in the electrolyte. Potential situations that need to be avoided, during electrorefining operations, include (i) fissile elements build up in the salt that might approach the criticality limits specified for the vessel, (ii) electrolyte freezing at the operating temperature of the electrorefiner due to changes in the liquidus temperature, and (iii) phase separation (non-homogenous solution). The stability (and homogeneity) of the phases can be monitored by studying the thermal characteristics of the molten salts as a function of impurity concentration. Simulated salt compositions consisting of the selected rare earth and alkaline earth chlorides, with a eutectic mixture of LiCl-KCl as the carrier electrolyte, were studied to determine the melting points (thermal characteristics) using a Differential Scanning Calorimeter (DSC). The experimental data were used to model the liquidus temperature. On the basis of the this data, it became possible to predict a spent fuel treatment processing scenario under which electrorefining could no longer be performed as a result of increasing liquidus temperatures of the electrolyte.

  18. Effect of transport on MAR in detached divertor plasma

    International Nuclear Information System (INIS)

    Miyamoto, Kenji; Hatayama, A.; Ishii, Y.; Miyamoto, T.; Fukano, A.

    2003-01-01

    The effect of H 2 transport on the onset of MAR in the relatively lower plasma parameter regime of a detached state (n e =1x10 19 m -3 , T e =1 eV) is investigated theoretically. The vibrationally excited molecular densities and the degree of MAR are evaluated by using a 1-D Monte Carlo method (with transport effect), and by solving time-dependent 0-D rate equations without the transport term (without transport effect), respectively. It is found that the degree of MAR with transport is smaller than that without transport under the same H 2 flow rate. Especially, the degree of MAR is negligible near the gas inlet. This smaller degree of MAR with transport is due to the lack of highly excited vibrational molecules which contribute to MAR. The hydrogen molecular density available for MAR is determined by the external hydrogen molecular source and the outflow due to transport, i.e., a 'net' confinement time

  19. Probing Gravitational Theories with Eccentric Eclipsing Detached Binary Stars

    Directory of Open Access Journals (Sweden)

    Leopoldo Milano

    2014-12-01

    Full Text Available In this paper, we compare the effects of different theories of gravitation on the apsidal motion of eccentric eclipsing detached binary stars. The comparison is performed by using the formalism of the post-Newtonian parametrization to calculate the theoretical advance at periastron and compare it to the observed one, after having considered the effects of the structure and rotation of the involved stars. A variance analysis on the results of this comparison shows that no signicant difference can be found due to the effect of the different theories under test with respect to the standard general relativity (GR. It will be possible to observe differences, as we would expect, by checking the observed period variation on a much larger lapse of time.

  20. A rare case of bilateral tractional retinal detachment following snakebite

    Directory of Open Access Journals (Sweden)

    Nicey Roy Thomas

    2017-01-01

    Full Text Available A 13-year-old female presented with diminution of vision in both eyes for 3 months following snakebite. Best-corrected visual acuities were hand movement in both eyes. Fundoscopy showed vitreous hemorrhage, and B-scan ultrasonography revealed an underlying tractional retinal detachment (TRD involving the macula in both eyes. Patient underwent 25-gauge pars plana vitrectomy in conjunction with belt buckling, endolaser, and silicone oil tamponade in the left eye. At 6 weeks postoperatively, best-corrected visual acuity of the left eye was noted to be 20/200 with settled TRD and attached retina. Bilateral proliferative retinopathy with TRD is a hitherto unreported complication of snake bite.

  1. Current Understanding of the Genetic Architecture of Rhegmatogenous Retinal Detachment.

    Science.gov (United States)

    Johnston, Timothy; Chandra, Aman; Hewitt, Alex W

    2016-06-01

    Rhegmatogenous retinal detachment (RRD) is a common and potentially blinding surgical retinal disease. While the precise molecular mechanisms leading to RRD are poorly understood, there is an increasing body of literature supporting the role of heritable factors in the pathogenesis of the condition. Much work has been undertaken investigating genes important in syndromic forms of RRD (e.g., Stickler, Wagner Syndrome, etc.) and research pertaining to genetic investigations of idiopathic or non-syndromic RRD has also recently been reported. To date, at least 12 genetic loci have been implicated in the development of syndromes of which RRD is a feature. A recent GWAS identified five loci implicated in the development of idiopathic RRD.This article provides an overview of the genetic mechanisms of both syndromic and idiopathic RRD. The genetics of predisposing conditions, such as myopia and lattice degeneration, are also discussed.

  2. Application of ultrasound in the diagnosis of posterior vitreous detachment

    Directory of Open Access Journals (Sweden)

    Hui-Wei Wang

    2013-12-01

    Full Text Available AIM: To investigate the utility of ultrasound in the diagnosis of posterior vitreous detachment(PVD. METHODS: From September 2011 to September 2012, 506 eyes of 305 cases(male 191, female 114of PVD patients in our hospital were checked and analyzed with ultrasound.RESULTS: Totally, 179 eyes were diagnosed as partial PVD, the proportion was 35.4%. And 327 eyes were diagnosed as complete PVD, the proportion was 64.6%. Among the 61 eyes(12.1%with a small amount of hemorrhage of vitreous humor,retinal breaks of 26 eyes(5.1%were founded. Given the photocoagulation nicely heal to the breaks and then recovered. CONCLUSION:Ultrasonography can accurately diagnose PVD. It has non-invasive,convenience, and other characteristics, and it is worthy of clinical popularization.

  3. Tamponade in surgery for retinal detachment associated with proliferative vitreoretinopathy.

    Science.gov (United States)

    Schwartz, Stephen G; Flynn, Harry W; Lee, Wen-Hsiang; Ssemanda, Elizabeth; Ervin, Ann-Margret

    2009-10-07

    Retinal detachment (RD) with proliferative vitreoretinopathy (PVR) often requires surgery. During surgery, a tamponade agent is needed to reduce the rate of recurrent retinal detachment. The objective of this review was to evaluate the benefits and adverse outcomes of surgery with various tamponade agents. We searched the Cochrane Controlled Register (CENTRAL), MEDLINE, EMBASE, Latin America and Carribbean Health Sciences (LILACS) and the UK Clinical Trials Gateway (UKCTG). There were no language or date restrictions in the search for trials. The electronic databases were last searched on 9 July 2009. We included randomized clinical trials comparing patients treated with various tamponade agents. Two individuals screened the search results independently. One study with two trials was eligible for inclusion in the review. One study with two trials was included in the review. The first trial randomized 151 eyes to receive either silicone oil or sulfur hexafluoride (SF(6)) gas tamponades; the second trial randomized 271 eyes to receive either silicone oil or perfluropropane (C(3)F(8)) gas tamponades. In patients with RD associated with PVR, pars plana vitrectomy and infusion of either silicone oil or perfluropropane gas appear comparable for a broad variety of cases. Sulfur hexafluoride gas was associated with worse anatomic and visual outcomes than either silicone oil or perfluropropane gas. The use of either C(3)F(8) or silicone oil appears reasonable for most patients with RD associated with PVR. Because there do not appear to be any major differences in outcomes between the two agents, the choice of a tamponade agent should be individualized for each patient.

  4. Surgical challenges and outcomes of rhegmatogenous retinal detachment in albinism.

    Science.gov (United States)

    Sinha, M K; Chhablani, J; Shah, B S; Narayanan, R; Jalali, S

    2016-03-01

    To report the outcomes and surgical difficulties during rhegmatogenous retinal detachment (RRD) repair in patients with albinism. Retrospective analysis of 10 eyes of 9 patients with albinism that underwent RRD repair was performed. Collected data included demographic details, preoperative examination details, surgical procedure, surgical difficulties, anatomical, and visual outcomes. Outcome measures were retinal reattachment and visual acuity at the last follow-up. Mean preoperative best-corrected visual acuity (BCVA) was logMAR (Logarithm of the Minimum Angle of Resolution) 2.15 (range 0.9-3.0) with preoperative localization of causative break in six eyes. One eye had proliferative vitreoretinopathy grade C1 preoperatively. Four eyes underwent scleral buckling (SB) and six underwent 20G pars plana vitrectomy (PPV) with silicone oil injection. Intraoperative complication as iatrogenic retinal break occurred in four eyes. For retinopexy during vitrectomy, endolaser delivery was possible in three out of six eyes, whereas three eyes had cryopexy. The mean follow-up was 12 months in SB group (range 1-12; median 12 months) and 5.33 months (range 1-12; median 3 months) in PPV group. Among vitrectomized eye, two eyes had recurrence at 3 months with oil in situ. Rest of the eyes had attached retina at last follow-up. Mean BCVA at last follow-up was logMAR -1.46 (range 0.7-2.0) with mean improvement of -0.57 logMAR. Identification of break, induction of posterior vitreous detachment, and endolaser delivery may be difficult during RRD repair in patients with albinism. The incidence of PVR appeared less in these eyes. Both SB and PPV were efficacious and appear to be good surgical techniques for use in this patient population.

  5. Characteristics and pattern of rhegmatogenous retinal detachment in pakistan.

    Science.gov (United States)

    Jamil, Muhammad Hannan; Farooq, Nesr; Khan, Muhammad Tariq; Jamil, Ahmed Zeeshan

    2012-08-01

    To determine the presenting characteristics of rhegmatogenous retinal detachment (RRD) in a consecutive series of Pakistani patients. Case series. Layton Rahmatullah Benevolent Trust (LRBT), Lahore, from June 2010 to October 2011. A total of 107 eyes underwent RRD surgery. Detailed diagrams were drawn pre-operatively for all. Other recorded details included, bio-data, age, gender, visual acuity, autorefractometery, predisposing risk factors, lens state and duration of symptoms. The data was analyzed with respect to age and gender distribution, frequency of various risk factors for RRD, duration of RRD and its various presenting characteristics. Mean age of the patients were 33.1 ± 1.5 years, 85% were males. Bilateral RRD was discovered in 2.8% patients. No identifiable risk factor for RRD was present in 28%, while in rest of the 72% eyes, the commonest risk factors were intraocular surgery, trauma and peripheral myopic degeneration in decreasing order of frequency. There were 70.1% phakic, 23.4% pseudophakic and 6.5% aphakic eyes. Majority (93.5%) presented with macula off detachment. There was an overall average time lapse of 97.24 ± 16.95 days between presenting and first occurrence of symptoms. In 31.8% of eyes no break could be found pre-operatively, while 38.3% had 1 and 29.9% eyes had ³ 2 breaks. Majority of the primary breaks were horse-shoe tears (42.1%). Total RRD was found in 35.5% eyes. Infero-temporal and supero-temporal were the most frequently involved quadrants (93.5% and 86.9% respectively). Intraocular surgery, trauma and lattice degeneration in myopia are established common risk factors for RRD. These patients deserve meticulous fundus examination with indentation indirect ophthalmoscopy by trained professionals.

  6. Grip and detachment of locusts on inverted sandpaper substrates

    International Nuclear Information System (INIS)

    Han Longbao; Wang Zhouyi; Ji Aihong; Dai Zhendong

    2011-01-01

    Locusts (Locusta migratoria manilensis) are characterized by their strong flying and grasping ability. Research on the grasping mechanism and behaviour of locusts on sloping substrates plays an important role in elucidating the mechanics of hexapod locomotion. Data on the maximum angles of slope at which locusts can grasp stably (critical angles of detachment) were obtained from high-speed video recordings at 215 fps. The grasping forces were collected by using two sensors, in situations where all left legs were standing on one and the right legs on the other sensor plate. These data were used to illustrate the grasping ability of locusts on slopes with varying levels of roughness. The grasping morphologies of locusts' bodies and tarsi were observed, and the surface roughness as well as diameters of their claw tips was measured under a microscope to account for the grasping mechanism of these insects on the sloping substrate. The results showed that the claw tips and part of the pads were in contact with the inverted substrate when the mean particle diameter was in the range of 15.3-40.5 μm. The interaction between pads and substrates may improve the stability of contact, and claw tips may play a key role in keeping the attachment reliable. A model was developed to explain the significant effects of the relative size of claw tips and mean particle diameter on grasping ability as well as the observed increase in lateral force (2.09-4.05 times greater than the normal force during detachment) with increasing slope angle, which indicates that the lateral force may be extremely important in keeping the contact reliable. This research lays the groundwork for the probable design and development of biomimetic robotics.

  7. Effects of Crop Canopies on Rain Splash Detachment

    Science.gov (United States)

    Ma, Bo; Yu, Xiaoling; Ma, Fan; Li, Zhanbin; Wu, Faqi

    2014-01-01

    Crops are one of the main factors affecting soil erosion in sloping fields. To determine the characteristics of splash erosion under crop canopies, corn, soybean, millet, and winter wheat were collected, and the relationship among splash erosion, rainfall intensity, and throughfall intensity under different crop canopies was analyzed through artificial rainfall experiments. The results showed that, the mean splash detachment rate on the ground surface was 390.12 g/m2·h, which was lower by 67.81% than that on bare land. The inhibiting effects of crops on splash erosion increased as the crops grew, and the ability of the four crops to inhibit splash erosion was in the order of winter wheat>corn>soybeans>millet. An increase in rainfall intensity could significantly enhance the occurrence of splash erosion, but the ability of crops to inhibit splash erosion was 13% greater in cases of higher rainfall intensity. The throughfall intensity under crop canopies was positively related to the splash detachment rate, and this relationship was more significant when the rainfall intensity was 40 mm/h. Splash erosion tended to occur intensively in the central row of croplands as the crop grew, and the non-uniformity of splash erosion was substantial, with splash erosion occurring mainly between the rows and in the region directly under the leaf margin. This study has provided a theoretical basis for describing the erosion mechanisms of cropland and for assisting soil erosion prediction as well as irrigation and fertilizer management in cultivated fields. PMID:24992386

  8. Grip and detachment of locusts on inverted sandpaper substrates

    Energy Technology Data Exchange (ETDEWEB)

    Han Longbao; Wang Zhouyi; Ji Aihong; Dai Zhendong, E-mail: zddai@nuaa.edu.cn [Institute of Bio-inspired Structure and Surface Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China)

    2011-12-15

    Locusts (Locusta migratoria manilensis) are characterized by their strong flying and grasping ability. Research on the grasping mechanism and behaviour of locusts on sloping substrates plays an important role in elucidating the mechanics of hexapod locomotion. Data on the maximum angles of slope at which locusts can grasp stably (critical angles of detachment) were obtained from high-speed video recordings at 215 fps. The grasping forces were collected by using two sensors, in situations where all left legs were standing on one and the right legs on the other sensor plate. These data were used to illustrate the grasping ability of locusts on slopes with varying levels of roughness. The grasping morphologies of locusts' bodies and tarsi were observed, and the surface roughness as well as diameters of their claw tips was measured under a microscope to account for the grasping mechanism of these insects on the sloping substrate. The results showed that the claw tips and part of the pads were in contact with the inverted substrate when the mean particle diameter was in the range of 15.3-40.5 {mu}m. The interaction between pads and substrates may improve the stability of contact, and claw tips may play a key role in keeping the attachment reliable. A model was developed to explain the significant effects of the relative size of claw tips and mean particle diameter on grasping ability as well as the observed increase in lateral force (2.09-4.05 times greater than the normal force during detachment) with increasing slope angle, which indicates that the lateral force may be extremely important in keeping the contact reliable. This research lays the groundwork for the probable design and development of biomimetic robotics.

  9. Mineral resource of the month: salt

    Science.gov (United States)

    Kostick, Dennis S.

    2010-01-01

    The article presents information on various types of salt. Rock salt is either found from underground halite deposits or near the surface. Other types of salt include solar salt, salt brine, and vacuum pan salt. The different uses of salt are also given including its use as a flavor enhancer, as a road deicing agent, and to manufacture sodium hydroxide.

  10. Retrospective Review of Ocular Point-of-Care Ultrasound for Detection of Retinal Detachment

    Science.gov (United States)

    Jacobsen, Bradley; Lahham, Sari; Lahham, Shadi; Patel, Amy; Spann, Sophia; Fox, John C.

    2016-01-01

    Introduction Retinal detachment is an ocular emergency that commonly presents to the emergency department (ED). Ophthalmologists are able to accurately make this diagnosis with a dilated fundoscopic exam, scleral depression or ophthalmic ultrasound when a view to the retina is obstructed. Emergency physicians (EPs) are not trained to examine the peripheral retina, and thus ophthalmic ultrasound can be used to aid in diagnosis. We assessed the accuracy of ocular point-of-care ultrasound (POCUS) in diagnosing retinal detachment. Methods We retrospectively reviewed charts of ED patients with suspected retinal detachment who underwent ocular POCUS between July 2012 and May 2015. Charts were reviewed for patients presenting to the ED with ocular complaints and clinical concern for retinal detachment. We compared ocular POCUS performed by EPs against the criterion reference of the consulting ophthalmologist’s diagnosis. Results We enrolled a total of 109 patients. Of the 34 patients diagnosed with retinal detachment by the ophthalmologists, 31 were correctly identified as having retinal detachment by the EP using ocular POCUS. Of the 75 patients who did not have retinal detachment, 72 were ruled out by ocular POCUS by the EP. This resulted in a POCUS sensitivity of 91% (95% CI [76–98]) and specificity of 96% (95% CI [89–99]). Conclusion This retrospective study suggests that ocular POCUS performed by EPs can aid in the diagnosis of retinal detachment in ED. PMID:26973752

  11. Retrospective Review of Ocular Point-of-Care Ultrasound for Detection of Retinal Detachment

    Directory of Open Access Journals (Sweden)

    Bradley Jacobsen, BS

    2016-03-01

    Full Text Available Introduction: Retinal detachment is an ocular emergency that commonly presents to the emergency department (ED. Ophthalmologists are able to accurately make this diagnosis with a dilated fundoscopic exam, scleral depression or ophthalmic ultrasound when a view to the retina is obstructed. Emergency physicians (EPs are not trained to examine the peripheral retina, and thus ophthalmic ultrasound can be used to aid in diagnosis. We assessed the accuracy of ocular point-ofcare ultrasound (POCUS in diagnosing retinal detachment. Methods: We retrospectively reviewed charts of ED patients with suspected retinal detachment who underwent ocular POCUS between July 2012 and May 2015. Charts were reviewed for patients presenting to the ED with ocular complaints and clinical concern for retinal detachment. We compared ocular POCUS performed by EPs against the criterion reference of the consulting ophthalmologist’s diagnosis. Results: We enrolled a total of 109 patients. Of the 34 patients diagnosed with retinal detachment by the ophthalmologists, 31 were correctly identified as having retinal detachment by the EP using ocular POCUS. Of the 75 patients who did not have retinal detachment, 72 were ruled out by ocular POCUS by the EP. This resulted in a POCUS sensitivity of 91% (95% CI [76-98] and specificity of 96% (95% CI [89-99]. Conclusion: This retrospective study suggests that ocular POCUS performed by EPs can aid in the diagnosis of retinal detachment in ED.

  12. Protein changes in the retina following experimental retinal detachment in rabbits

    DEFF Research Database (Denmark)

    Mandal, Nakul; Lewis, Geoffrey P; Fisher, Steven K

    2011-01-01

    Retinal detachment leads to the widespread cellular remodeling of the retina. The purpose of this study was to identify protein changes that accompany these cellular alterations by comparing the proteomic profiles of sham and experimentally detached rabbit retina. Elucidation of the proteins most...

  13. Inicial nasal mucosa detachment using piezoelectric device in the Le Fort I osteotomy: A technical note

    OpenAIRE

    Shinohara, Elio Hitoshi; Kaba, Shajadi Carlos Pardo; Ruiz, Marcelo Martinson; Horikawa, Fernando Kendi

    2013-01-01

    In maxillary Le Fort I type osteotomy the detachment of the nasal mucosa should be done carefully. Piezoelectric surgery contributed much to increase the safety of osteotomies, despite the initial advantage of minimizing the risk of injury in nervous tissue, mainly in bilateral sagittal split osteotomy; we use the piezoelectric device for the initial detachment of the nasal mucosa in the maxillary osteotomy.

  14. Detachment from Parents, Problem Behaviors, and the Moderating Role of Parental Support among Italian Adolescents

    Science.gov (United States)

    Pace, Ugo; Zappulla, Carla

    2013-01-01

    This study examined the relationship of emotional detachment from parents, parental support, and problem behaviors and focused on the unique and common contribution that detachment and parental support made to internalizing and externalizing behavioral problems. A total of 461 young adolescents, 13 to 14 years old ("M" = 13.4;…

  15. Round atrophic holes in lattice degeneration--an important cause of phakic retinal detachment.

    Science.gov (United States)

    Tillery, W V; Lucier, A C

    1976-01-01

    Round atrophic holes in lattice degeneration are an important cause of phakic retinal detachment. Detachments due solely to round holes in lattice accounted for almost 2.8% of all retinal detachments treated at Wills Eye Hospital from January 1970 to August 1973. These detachments had the following important characteristics: 1. One of the patients were under the age of 30 years. 2. Over 75% of the patients had refractive errors more myopic than -3 D spherical equivalent. 3. Inferior detachments were slightly more common than superior detachments. When located inferiorly, there was a tendency for slow progression as indicated by the frequent presence of pigmented demarcation lines. 4. Surgical repair with standard scleral buckling techniques was successful in 98% of these detachments. Young, moderate to highly myopic patients with round holes in areas of lattice degeneration seem to have a greater risk of developing this type of detachment. Patients with the triad of youth, myopia, and round holes in lattice degeneration deserve close observation.

  16. Efficacy of ophthalmic solutions to detach adhering Pseudomonas aeruginosa from contact lenses

    NARCIS (Netherlands)

    Landa, AS; van der Mei, HC; van Rij, G; Busscher, HJ

    Purpose. To compare the efficacies of two all-in-one contact lens (CL) cleaning solutions and a detergent mixture on the detachment of a pathogenic bacterium adhering to two types of contact lenses in the absence and presence of a tear film. Methods. Bacterial-detachment studies were carried out in

  17. Processes of electron attachment and detachment in near breakdown conditions in air plasma

    Science.gov (United States)

    Ardelyan, N.; Bychkov, V.; Belousov, A.; Kosmachevskii, K.

    2017-11-01

    Results of theoretical research on ionization of dry air at different low and moderate values of constant electric field are described. Special attention to the processes of electron attachment to oxygen molecules and electron detachment from negative ions has been paid. New data on the detachment of electrons from oxygen molecular negative ions are taken into account.

  18. Analysis of bacterial detachment from substratum surfaces by the passage of air-liquid interfaces

    NARCIS (Netherlands)

    Gomez-Suarez, C; Busscher, HJ; van der Mei, HC

    A theoretical analysis of the detachment of bacteria adhering to substratum surfaces upon the passage of an air-liquid interface is given, together with experimental results for bacterial detachment in the absence and presence of a conditioning film on different substratum surfaces. Bacteria

  19. Postoperative recovery of visual function after macula-off rhegmatogenous retinal detachment

    NARCIS (Netherlands)

    van de Put, Mathijs A. J.; Croonen, Danna; Nolte, Ilja M.; Japing, Wouter J.; Hooymans, Johanna M. M.; Los, Leonoor I.

    2014-01-01

    Purpose: To determine which factors affect the recovery of visual function in macula-off rhegmatogenous retinal detachment (RRD). Methods: In a prospective study of forty-five patients with a primary macula-off RRD of 24 hours to 6 weeks duration, the height of the macular detachment was determined

  20. Mechanism for salt scaling

    Science.gov (United States)

    Valenza, John J., II

    Salt scaling is superficial damage caused by freezing a saline solution on the surface of a cementitious body. The damage consists of the removal of small chips or flakes of binder. The discovery of this phenomenon in the early 1950's prompted hundreds of experimental studies, which clearly elucidated the characteristics of this damage. In particular it was shown that a pessimum salt concentration exists, where a moderate salt concentration (˜3%) results in the most damage. Despite the numerous studies, the mechanism responsible for salt scaling has not been identified. In this work it is shown that salt scaling is a result of the large thermal expansion mismatch between ice and the cementitious body, and that the mechanism responsible for damage is analogous to glue-spalling. When ice forms on a cementitious body a bi-material composite is formed. The thermal expansion coefficient of the ice is ˜5 times that of the underlying body, so when the temperature of the composite is lowered below the melting point, the ice goes into tension. Once this stress exceeds the strength of the ice, cracks initiate in the ice and propagate into the surface of the cementitious body, removing a flake of material. The glue-spall mechanism accounts for all of the characteristics of salt scaling. In particular, a theoretical analysis is presented which shows that the pessimum concentration is a consequence of the effect of brine pockets on the mechanical properties of ice, and that the damage morphology is accounted for by fracture mechanics. Finally, empirical evidence is presented that proves that the glue-small mechanism is the primary cause of salt scaling. The primary experimental tool used in this study is a novel warping experiment, where a pool of liquid is formed on top of a thin (˜3 mm) plate of cement paste. Stresses in the plate, including thermal expansion mismatch, result in warping of the plate, which is easily detected. This technique revealed the existence of

  1. Mechanisms of redox metabolism and cancer cell survival during extracellular matrix detachment.

    Science.gov (United States)

    Hawk, Mark A; Schafer, Zachary T

    2018-01-16

    Non-transformed cells that become detached from the extracellular matrix (ECM) undergo dysregulation of redox homeostasis and cell death. In contrast, cancer cells often acquire the ability to mitigate programmed cell death pathways and recalibrate the redox balance to survive after ECM detachment, facilitating metastatic dissemination. Accordingly, recent studies of the mechanisms by which cancer cells overcome ECM detachment-induced metabolic alterations have focused on mechanisms in redox homeostasis. The insights into these mechanisms may inform the development of therapeutics that manipulate redox homeostasis to eliminate ECM-detached cancer cells. Here, we review how ECM-detached cancer cells balance redox metabolism for survival. Published under license by The American Society for Biochemistry and Molecular Biology, Inc.

  2. The Development of a Cat Model of Retinal Detachment and Re-attachment.

    Science.gov (United States)

    Wassmer, Sarah; Leonard, Brian C; Coupland, Stuart G; Baker, Adam; Hamilton, John; Torlone, Renée; Zacks, David N; Tsilfidis, Catherine

    2016-01-01

    We present an optimized surgical technique for feline retinal detachment which allows for natural re-attachment, reduces retinal scarring and vitreal bands, and allows central placement of the detachment in close proximity to the optic nerve. This enables imaging via Optical Coherence Tomography (OCT) and multifocal electroretinography (mfERG) analysis. Ideal detachment conditions involve a lensectomy followed by a three-port pars plana vitrectomy. A 16-20 % retinal detachment is induced by injecting 8 % C3F8 gas into the subretinal space in the central retina with a 42G cannula. The retinal detachment resolves approximately 6 weeks post-surgery. Imaging is enhanced by using a 7.5 and 20 diopter lens for OCT and mfERG fundus imaging, respectively, to compensate for the removed lens.

  3. The influence of refractive error and lattice degeneration on the incidence of retinal detachment.

    Science.gov (United States)

    Burton, T C

    1989-01-01

    This study indicates the feasibility of stratifying the general population into various risk pools for retinal detachment depending on a person's age, refractive status, and the presence of lattice degeneration. At first impression the risks seem at variance with the fine clinical studies of Byer, who has shown a very low detachment rate in the population with lattice degeneration. In all likelihood the vast majority of his patients were emmetropic or mildly myopic, so that very few would be expected to develop detachments during their entire lifetimes, let along during intervals of only 10 to 20 years. This study shows the futility of following, or treating prophylactically, young emmetropic individuals with lattice degeneration. Assuming that prophylaxis is actually effective, one would have to treat 1000 emmetropic lattice patients in the 30 to 39 year age group to prevent a single detachment over a 10-year period. Lattice patients with low to moderate degrees of myopia tend to develop detachments between 40 and 60 years of age caused by premature posterior vitreous separation and tractional tears. Clearly prophylaxis for this group is not warranted, since only 5% to 10% of these individuals will experience detachments in their lifetimes. On the other hand this study has verified the previous suspicions that persons with myopia exceeding -5.0 D accompanied by lattice degeneration have an extraordinarily high risk of detachment during their lifetimes. Detachments in this group tend to cluster in the second, third, and fourth decades, are typically caused by atrophic holes, are slowly progressive, and are often simultaneously bilateral. Enhanced vigilance is certainly appropriate during this time and perhaps consideration should be given to prophylactically treating this group. This would be no small task, since within a population of 1 million persons there would be about 1150 aged 10 to 39 years with myopia exceeding -5.0 D and lattice degeneration. Only 4

  4. Salt repository design approach

    International Nuclear Information System (INIS)

    Matthews, S.C.

    1983-01-01

    This paper presents a summary discussion of the approaches that have been and will be taken in design of repository facilities for use with disposal of radioactive wastes in salt formations. Since specific sites have yet to be identified, the discussion is at a general level, supplemented with illustrative examples where appropriate. 5 references, 1 figure

  5. Crossing the Salt Barrier

    Indian Academy of Sciences (India)

    Fry. RIVER. To cross the salt barrier is, therefore, an obligatory part of every amphihaline fish cycle. Figure 2a. Life Cycle of. Salmon. Adult salmon migrate from sea towards the river. After reaching their hatching ground, the eggs are laid in the gravel. The spawned fishes are called kelts. Alevin is a stage from hatching to fry.

  6. Molten salt reactor concept

    International Nuclear Information System (INIS)

    Sood, D.D.

    1980-01-01

    Molten salt reactor is an advanced breeder concept which is suited for the utilization of thorium for nuclear power production. This reactor is based on the use of solutions of uranium or plutonium fluorides in LiF-BeF 2 -ThF 4 as fuel. Unlike the conventional reactors, no external coolant is used in the reactor core and the fuel salt itself is circulated through heat exchangers to transfer the fission produced heat to a secondary salt (NaF-NaBF 4 ) for steam generation. A part of the fuel stream is continuously processed to isolate 233 Pa, so that it can decay to fissile 233 U without getting converted to 234 Pa, and for the removal of neutron absorbing fission products. This on-line processing scheme makes this reactor concept to achieve a breeding ratio of 1.07 which is the highest for any thermal breeder reactor. Experimental studies at the Bhabha Atomic Research Centre, Bombay, have established the use of plutonium as fuel for this reactor. This molten salt reactor concept is described and the work conducted at the Bhabha Atomic Research Centre is summarised. (auth.)

  7. Salt og forbrugervalg

    DEFF Research Database (Denmark)

    Mørk, Trine; Grunert, Klaus G

    Linket til højre henviser til rapporten i trykt format til download. Dokumentet over linket er selve leveringen til ministeriet med følgebrev. Viden om forbrugernes holdning til og købsintention for saltreducerede fødevarer er central, i forhold til industriens udvikling af nye produkter og...... af saltreducerede fødevarer og deres købsintention af disse. Dette blev undersøgt ved at måle forbrugerens viden om salt, anvendelse af salt, ønske om reduktion af salt og købsintention af saltreducerede fødevarer i en web-baseret undersøgelse. Efter den web-baserede undersøgelse, blev de samme mål...... undersøgt, men i et supermarked, hvor deltagerne blev inddelt i fire grupper for at undersøge effekten af priming og saltmærkning. Desuden blev der foretaget 15 kvalitative interviews, for at studere hvem og hvad der karakteriserer de deltagere i eksperimentet, som enten ender med ingen salt...

  8. Borehole closure in salt

    International Nuclear Information System (INIS)

    Fuenkajorn, K.; Daemen, J.J.K.

    1988-12-01

    Constitutive law parameters are determined from salt behavior characterization experiments. The results are applied to predict creep (time-dependent) closure of boreholes in salt specimens subjected to various loading configurations. Rheological models (linear and nonlinear viscoelastic and viscoplastic models), empirical models, and physical theory models have been formulated from the results of uniaxial creep tests, strain and stress rate controlled uniaxial tests, constant strain rate triaxial tests, cyclic loading tests, and seismic velocity measurements. Analytical solutions for a thick-walled cylinder subjected to internal and external pressures and for a circular hole in an infinite plate subjected to a biaxial or uniaxial stressfield have been derived from each of the linear viscoelastic models and from one of the empirical laws. The experimental results indicate that the salt samples behave as an elastic-viscoplastic material. The elastic behavior tends to be linear and time-independent. The plastic deformation is time-dependent. The stress increment to strain rate increment ratio gradually decreases as the stress level increases. The transient potential creep law seems to give the simplest satisfactory governing equation describing the viscoplastic behavior of salt during the transient phase. 204 refs., 27 figs., 29 tabs

  9. Learning SaltStack

    CERN Document Server

    Myers, Colton

    2015-01-01

    If you are a system administrator who manages multiple servers, then you know how difficult it is to keep your infrastructure in line. If you've been searching for an easier way, this book is for you. No prior experience with SaltStack is required.

  10. Evaluation of the macular architecture of patients operated on from macula-off rhegmatogenous retinal detachment using optical coherence tomography

    International Nuclear Information System (INIS)

    Ramos Lopez, Meisy; Obret Mendive, Isabel; Hernandez Silva, Juan Raul

    2010-01-01

    With the support of optical coherence tomography, to evaluate the macular condition of the patients operated on from rhegmatogenous retinal detachment, with detached macula, who underwent buckling surgery and pars plana vitrectomy

  11. EARLY SIMULTANEOUS FUNDUS AUTOFLUORESCENCE AND OPTICAL COHERENCE TOMOGRAPHY FEATURES AFTER PARS PLANA VITRECTOMY FOR PRIMARY RHEGMATOGENOUS RETINAL DETACHMENT

    NARCIS (Netherlands)

    Dellʼomo, Roberto; Mura, Marco; Lesnik Oberstein, Sarit Y.; Bijl, Heico; Tan, H. Stevie

    2012-01-01

    Purpose: To describe fundus autofluorescence and optical coherence tomography (OCT) features of the macula after pars plana vitrectomy for rhegmatogenous retinal detachment. Methods: Thirty-three eyes of 33 consecutive patients with repaired rhegmatogenous retinal detachment with or without the

  12. [Stickler's syndrome (dystrophia vitreoretinalis hereditaria). Results of surgery for retinal detachment].

    Science.gov (United States)

    Karel, I; Dolezalová, J; Oudová, P

    2001-05-01

    Stickler's syndrome (SS) is an autosomal dominant hereditary disease of the collagenous connective tissue where impaired development of the vitreous body gel and peripheral retina and detachment of the retina are associated with general manifestations. The objective of the retrospective study was to evaluate the long-term results of surgery of retinal detachment in SS. The group of patients comprised 7 patients, 6 men and 1 woman aged 4 to 45 years, average age 16.8 years. Autosomal dominant heredity was obvious in 6 members (85.7%) of two families. General manifestations of SS included abnormalities of the facial skeleton (6 patients), cleft palate (4 patients), impaired hearing (2 patients), marfanoid habitus (2 patients) and hyperextensibility of the joints (4 patients). In the eyes with SS was manifested by myopia from -1 to -9 D and a liquid vitreous body. Multiple foci of lattice degeneration supplemented the finding in 6 patients (85.7%). Detachment of the retina was a manifestation of SS in 12 of 14 eyes (85.7%). It was manifested in 5 of 7 patients concurrently or within 12 years in both eyes. The causes of retinal detachment were multiple equatorial and postequatorial tears due to lattice degeneration in 8 eyes (66.7%) or a giant tear in 4 eyes (33.3%). Advanced proliferative vitreoretinopathy (PVR) was associated with retinal detachment in 8 eyes (66.7%) and in 6 eyes (50%) it was not possible to assess the beginning of retinal detachment. In 3 of 5 patients with bilateral retinal detachment the adverse course of retinal detachment on the first eye was followed 8 to 12 years previously in another department: two retinal detachments with giant tears were evaluated as inoperable and one inveterated detachment with advanced PVR was operated unsuccessfully. Retinal detachment was operated in 9 eyes of 7 patients, in two patients both eyes were operated simultaneously. The patients were followed up after surgery for 11 months to 15 years, on average for 65

  13. Metals removal from spent salts

    Science.gov (United States)

    Hsu, Peter C.; Von Holtz, Erica H.; Hipple, David L.; Summers, Leslie J.; Brummond, William A.; Adamson, Martyn G.

    2002-01-01

    A method and apparatus for removing metal contaminants from the spent salt of a molten salt oxidation (MSO) reactor is described. Spent salt is removed from the reactor and analyzed to determine the contaminants present and the carbonate concentration. The salt is dissolved in water, and one or more reagents may be added to precipitate the metal oxide and/or the metal as either metal oxide, metal hydroxide, or as a salt. The precipitated materials are filtered, dried and packaged for disposal as waste or can be immobilized as ceramic pellets. More than about 90% of the metals and mineral residues (ashes) present are removed by filtration. After filtration, salt solutions having a carbonate concentration >20% can be spray-dried and returned to the reactor for re-use. Salt solutions containing a carbonate concentration ion exchange column, which yields salt solutions that contain less than 1.0 ppm of contaminants.

  14. Actinide removal from spent salts

    Science.gov (United States)

    Hsu, Peter C.; von Holtz, Erica H.; Hipple, David L.; Summers, Leslie J.; Adamson, Martyn G.

    2002-01-01

    A method for removing actinide contaminants (uranium and thorium) from the spent salt of a molten salt oxidation (MSO) reactor is described. Spent salt is removed from the reactor and analyzed to determine the contaminants present and the carbonate concentration. The salt is dissolved in water, and one or more reagents are added to precipitate the thorium as thorium oxide and/or the uranium as either uranium oxide or as a diuranate salt. The precipitated materials are filtered, dried and packaged for disposal as radioactive waste. About 90% of the thorium and/or uranium present is removed by filtration. After filtration, salt solutions having a carbonate concentration >20% can be dried and returned to the reactor for re-use. Salt solutions containing a carbonate concentration salt solutions that contain less than 0.1 ppm of thorium or uranium.

  15. Dietary salt and gastric ulcer.

    OpenAIRE

    Sonnenberg, A

    1986-01-01

    Statistically significant linear correlations between geographic variations in salt consumption and mortality from gastric, but not duodenal ulcer, are reported. It is suggested that dietary consumption of salt is a risk factor in mortality from gastric ulcer.

  16. Should we eat less salt?

    Science.gov (United States)

    Delahaye, François

    2013-05-01

    High blood pressure is a major cardiovascular risk factor. There is overwhelming evidence that high salt consumption is a major cause of increased blood pressure. There is also a link between high salt consumption and risk of stroke, left ventricular hypertrophy, renal disease, obesity, renal stones and stomach cancer. Reducing salt consumption leads to a decrease in blood pressure and the incidence of cardiovascular disease. There are no deleterious effects associated with reducing salt consumption and it is also very cost-effective. Many organizations and state governments have issued recommendations regarding the suitable amount of salt consumption. In France, the objective is a salt consumptionsalt comes from manufactured products in developed countries, reduction of salt consumption requires the participation of the food industry. The other tool is consumer information and education. Salt consumption has already decreased in France in recent years, but efforts must continue. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  17. Salt ingestion caves.

    Directory of Open Access Journals (Sweden)

    Lundquist Charles A.

    2006-01-01

    Full Text Available Large vertebrate herbivores, when they find a salt-bearing layer of rock, say in a cliff face, can produce sizable voids where, overgenerations, they have removed and consumed salty rock. The cavities formed by this natural animal process constitute a uniqueclass of caves that can be called salt ingestion caves. Several examples of such caves are described in various publications. Anexample in Mississippi U.S.A., Rock House Cave, was visited by the authors in 2000. It seems to have been formed by deer orbison. Perhaps the most spectacular example is Kitum Cave in Kenya. This cave has been excavated to a length over 100 metersby elephants. An ancient example is La Cueva del Milodon in Chile, which is reported to have been excavated by the now extinctmilodon, a giant ground sloth. Still other possible examples can be cited. This class of caves deserves a careful definition. First, thecavity in rock should meet the size and other conventions of the locally accepted definition of a cave. Of course this requirement differsin detail from country to country, particularly in the matter of size. The intent is to respect the local conventions. The characteristicthat human entry is possible is judged to be a crucial property of any recognized cave definition. Second, the cavity should besignificantly the result of vertebrate animal consumption of salt-bearing rock. The defining process is that rock removed to form thecave is carried away in the digestive track of an animal. While sodium salts are expected to be the norm, other salts for which thereis animal hunger are acceptable. Also some other speleogenesis process, such as solution, should not be excluded as long as it issecondary in formation of a cave in question.

  18. The SALT HRS Spectrograph

    Science.gov (United States)

    Tyas, Luke Martin Graham

    2012-05-01

    SALT HRS (Southern African Large Telescope High Resolution Échelle Spectrograph) is a high-resolution, high-efficiency spectrograph for the 11m SALT telescope in Sutherland, South Africa. The initial optical design work was performed at the University of Canterbury, New Zealand. Revisions to the concept, the mechanical design, manufacture, assembly and testing have been handled by the Centre for Advanced Instrumentation, at Durham University in the United Kingdom. SALT HRS is a fibre-fed échelle grating spectrograph with four operational modes: low-, medium- and high-resolution and high-stability modes, having spectral resolutions of R≈16000, 37000, 67000 and 67000 respectively over a wavelength range of 370-890nm. The instrument is of a dual channel, 'white pupil' design, in which the primary mirror acts to collimate light onto a single R4 échelle grating, and also to focus dispersed light to an intermediate focus. A dichroic beam-splitter separates the dispersed light into two separate spectral channels. Spherical pupil mirrors transfer the separated beams via a fold mirror to two wavelength-specific volume-phase holographic gratings (VPHGs) used as cross-dispersers. Cross-dispersed spectra are then imaged by two fully dioptric camera systems onto optimized CCD detectors. This thesis presents the results of the laboratory testing and specification of several critical sub-systems of SALT HRS, as well as the development of key software tools for the design verification and operation at the telescope. In Chapter 1 we first review the technical development of high-resolution spectroscopy and its specific implementation in SALT HRS. In Chapter 2 we develop a comprehensive throughput model of the entire system based on a combination of as-built performance and specific throughput measurements in the laboratory. This is used to make some specific predictions for the on-sky performance of SALT HRS and the magnitude limits for science targets. We also present a

  19. Ex vivo comparative study on three sinus lift tools for transcrestal detaching maxillary sinus mucosa.

    Science.gov (United States)

    Li, Yanfeng; Hu, Pin; Han, Yishi; Fan, Jiadong; Dong, Xinming; Ren, Huan; Yang, Chunhao; Shi, Tingting; Xia, Dong

    2017-07-04

    The objective of this study was to comparatively evaluate 3 different sinus lift tools, namely umbrella-shaped sinus lift curette YSL-04, our recently designed probe-improved sinus lift curettes, and our newly invented elevator 014, using our previous developed goat ex vivo models for direct visualizing the effectiveness of detaching sinus mucosa in real time. Goat ex vivo models for direct visualizing the effectiveness of detaching sinus mucosa in real time were generated according to our previously developed protocol. The effectiveness for each tool was evaluated through the length of sinus mucosa detached in mesial and distal directions or buccal and palatal directions, and the space volume created by detaching maxillary sinus mucosa in mesial, distal, buccal and palatal directions. The results showed that all 3 sinus lift tools could transcrestally detach the maxillary sinus mucosa and create extra space under the elevated sinus floor on the goat ex vivo sinus models. Moreover, our newly invented elevator 014 had advantages over the other 2 in term of the capability to detach the sinus mucosa. Our newly invented elevator 014 might be a promising tool for detaching maxillary sinus mucosa in transcrestal maxillary sinus floor elevation.

  20. Quaternary low-angle slip on detachment faults in Death Valley, California

    Science.gov (United States)

    Hayman, N.W.; Knott, J.R.; Cowan, D.S.; Nemser, E.; Sarna-Wojcicki, A. M.

    2003-01-01

    Detachment faults on the west flank of the Black Mountains (Nevada and California) dip 29??-36?? and cut subhorizontal layers of the 0.77 Ma Bishop ash. Steeply dipping normal faults confined to the hanging walls of the detachments offset layers of the 0.64 Ma Lava Creek B tephra and the base of 0.12-0.18 Ma Lake Manly gravel. These faults sole into and do not cut the low-angle detachments. Therefore the detachments accrued any measurable slip across the kinematically linked hanging-wall faults. An analysis of the orientations of hundreds of the hanging-wall faults shows that extension occurred at modest slip rates (<1 mm/yr) under a steep to vertically oriented maximum principal stress. The Black Mountain detachments are appropriately described as the basal detachments of near-critical Coulomb wedges. We infer that the formation of late Pleistocene and Holocene range-front fault scarps accompanied seismogenic slip on the detachments.

  1. Measuring the force of single protein molecule detachment from surfaces with AFM.

    Science.gov (United States)

    Tsapikouni, Theodora S; Missirlis, Yannis F

    2010-01-01

    Atomic force microscopy (AFM) was used to measure the non-specific detachment force of single fibrinogen molecules from glass surfaces. The identification of single unbinding events was based on the characteristics of the parabolic curves, recorded during the stretching of protein molecules. Fibrinogen molecules were covalently bound to Si(3)N(4) AFM tips, previously modified with 3-aminopropyl-dimethyl-ethoxysilane, through a homobifunctional poly(ethylene glycol) linker bearing two hydroxysulfosuccinimide esters. The most probable detachment force was found to be 210 pN, when the tip was retracting with a velocity of 1400 nm/s, while the distribution of the detachment distances indicated that the fibrinogen chain can be elongated beyond the length of the physical conformation before detachment. The dependence of the most probable detachment force on the loading rate was examined and the dynamics of fibrinogen binding to the surface were found amenable to the simple expression of the Bell-Evans theory. The theory's expansion, however, by incorporating the concept of the rupture of parallel residue-surface bonds could only describe the detachment of fibrinogen for a small number of such bonds. Finally, the mathematical expression of the Worm-Like Chain model was used to fit the stretching curves before rupture and two interpretations are suggested for the description of the AFM curves with multiple detachment events.

  2. Does unintentional macular translocation after retinal detachment repair influence visual outcome?

    Science.gov (United States)

    Pandya, Vivek B; Ho, I-Van; Hunyor, Alex P

    2012-01-01

    To document the occurrence of postoperative macular translocation after retinal detachment repair and discuss its influence on visual outcome. Retrospective case series in a tertiary care setting. Five eyes of five patients presenting to our clinic with macula-off rhegmatogenous retinal detachment. All patients underwent surgical repair of the retinal detachment, with regular postoperative follow-up, including macular optical coherence tomography and fundus autofluorescence. Visual acuity and subjective visual symptoms in patients with anatomically successful retinal detachment repair, in whom inadvertent macular translocation was noted. Our series demonstrates the presence of unintentional macular translocation after retinal detachment repair, detected by fundus autofluorescence imaging. In contrast to previous reports, we document inadvertent macular translocation in one patient after scleral buckling surgery. In each case, the retina was fully reattached postoperatively and no other complications were identified. There was variability in the symptoms and objective visual outcomes after surgery. Inadvertent macular translocation can occur following repair of macula-off retinal detachment, and may be a significant contributor to poorer visual outcome after retinal detachment, despite objective surgical success. © 2011 The Authors. Clinical and Experimental Ophthalmology © 2011 Royal Australian and New Zealand College of Ophthalmologists.

  3. Tauroursodeoxycholic Acid (TUDCA) Protects Photoreceptors from Cell Death after Experimental Retinal Detachment

    Science.gov (United States)

    Mantopoulos, Dimosthenis; Murakami, Yusuke; Comander, Jason; Thanos, Aristomenis; Roh, Miin; Miller, Joan W.; Vavvas, Demetrios G.

    2011-01-01

    Background Detachment of photoreceptors from the underlying retinal pigment epithelium is seen in various retinal disorders such as retinal detachment and age-related macular degeneration and leads to loss of photoreceptors and vision. Pharmacologic inhibition of photoreceptor cell death may prevent this outcome. This study tests whether systemic administration of tauroursodeoxycholic acid (TUDCA) can protect photoreceptors from cell death after experimental retinal detachment in rodents. Methodology/Principal Findings Retinal detachment was created in rats by subretinal injection of hyaluronic acid. The animals were treated daily with vehicle or TUDCA (500 mg/kg). TUNEL staining was used to evaluate cell death. Photoreceptor loss was evaluated by measuring the relative thickness of the outer nuclear layer (ONL). Macrophage recruitment, oxidative stress, cytokine levels, and caspase levels were also quantified. Three days after detachment, TUDCA decreased the number of TUNEL-positive cells compared to vehicle (651±68/mm2 vs. 1314±68/mm2, P = 0.001) and prevented the reduction of ONL thickness ratio (0.84±0.03 vs. 0.65±0.03, P = 0.002). Similar results were obtained after 5 days of retinal detachment. Macrophage recruitment and expression levels of TNF-a and MCP-1 after retinal detachment were not affected by TUDCA treatment, whereas increases in activity of caspases 3 and 9 as well as carbonyl-protein adducts were almost completely inhibited by TUDCA treatment. Conclusions/Significance Systemic administration of TUDCA preserved photoreceptors after retinal detachment, and was associated with decreased oxidative stress and caspase activity. TUDCA may be used as a novel therapeutic agent for preventing vision loss in diseases that are characterized by photoreceptor detachment. PMID:21961034

  4. A Meta-Analysis on Antecedents and Outcomes of Detachment from Work.

    Science.gov (United States)

    Wendsche, Johannes; Lohmann-Haislah, Andrea

    2016-01-01

    Detachment from work has been proposed as an important non-work experience helping employees to recover from work demands. This meta-analysis (86 publications, k = 91 independent study samples, N = 38,124 employees) examined core antecedents and outcomes of detachment in employee samples. With regard to outcomes, results indicated average positive correlations between detachment and self-reported mental (i.e., less exhaustion, higher life satisfaction, more well-being, better sleep) and physical (i.e., lower physical discomfort) health, state well-being (i.e., less fatigue, higher positive affect, more intensive state of recovery), and task performance (small to medium sized effects). However, average relationships between detachment and physiological stress indicators and work motivation were not significant while associations with contextual performance and creativity were significant, but negative. Concerning work characteristics, as expected, job demands were negatively related and job resources were positively related to detachment (small sized effects). Further, analyses revealed that person characteristics such as negative affectivity/neuroticism (small sized effect) and heavy work investment (medium sized effect) were negatively related to detachment whereas detachment and demographic variables (i.e., age and gender) were not related. Moreover, we found a medium sized average negative relationship between engagement in work-related activities during non-work time and detachment. For most of the examined relationships heterogeneity of effect sizes was moderate to high. We identified study design, samples' gender distribution, and affective valence of work-related thoughts as moderators for some of these aforementioned relationships. The results of this meta-analysis point to detachment as a non-work (recovery) experience that is influenced by work-related and personal characteristics which in turn is relevant for a range of employee outcomes.

  5. Optic Nerve Head Hemorrhages Associated With Posterior Vitreous Detachment.

    Science.gov (United States)

    Polkinghorne, Philip J

    2018-01-01

    To report and evaluate the clinical and optical coherence tomography (OCT) features of optic nerve hemorrhages (ONH) associated with spontaneous posterior vitreous detachment (PVD). A prospective case series conducted at a private ophthalmic practice in Auckland, New Zealand. A consecutive series of patients presenting at a private multispecialty practice in Auckland, New Zealand, with symptoms of PVD with ONH underwent imaging of the optic nerve with digital retinal photography and OCT. The number and location of each hemorrhage were recorded, together with relevant ophthalmic and demographic data. Twenty of 30 eyes with ONH had evidence of persistent vitreopapillary adhesion. Three patterns of adhesion were identified: central, peripheral, and combined. In all, 52 hemorrhages were identified, of which the majority were flame-shaped, although other types were seen including dot and blot hemorrhages. One subretinal hemorrhage occurred in a patient with a central vitreopapillary adhesion. ONH hemorrhages associated with PVD are commonly found with persistent vitreopapillary adhesions as evidenced on OCT. The clinical features of ONH together with OCT imaging may help to distinguish ONH associated with PVD from other hemorrhages found on or adjacent to the optic nerve. Copyright 2017 Asia-Pacific Academy of Ophthalmology.

  6. Testing stellar evolution models with detached eclipsing binaries

    Science.gov (United States)

    Higl, J.; Weiss, A.

    2017-12-01

    Stellar evolution codes, as all other numerical tools, need to be verified. One of the standard stellar objects that allow stringent tests of stellar evolution theory and models, are detached eclipsing binaries. We have used 19 such objects to test our stellar evolution code, in order to see whether standard methods and assumptions suffice to reproduce the observed global properties. In this paper we concentrate on three effects that contain a specific uncertainty: atomic diffusion as used for standard solar model calculations, overshooting from convective regions, and a simple model for the effect of stellar spots on stellar radius, which is one of the possible solutions for the radius problem of M dwarfs. We find that in general old systems need diffusion to allow for, or at least improve, an acceptable fit, and that systems with convective cores indeed need overshooting. Only one system (AI Phe) requires the absence of it for a successful fit. To match stellar radii for very low-mass stars, the spot model proved to be an effective approach, but depending on model details, requires a high percentage of the surface being covered by spots. We briefly discuss improvements needed to further reduce the freedom in modelling and to allow an even more restrictive test by using these objects.

  7. A xylogalacturonan epitope is specifically associated with plant cell detachment

    DEFF Research Database (Denmark)

    Willats, William George Tycho; McCartney, L.; Steele-King, C.G.

    2004-01-01

    A monoclonal antibody (LM8) was generated with specificity for xyloglacturonan (XGA) isolated from pea (Pisum sativum L.) testae. Characterization of the LM8 epitope indicates that it is a region of XGA that is highly substituted with xylose. Immunocytochemical analysis indicates that this epitop...... that is specifically associated with a plant cell separation process that results in complete cell detachment....... is restricted to loosely attached inner parenchyma cells at the inner face of the pea testa and does not occur in other cells of the testa. Elsewhere in the pea seedling, the LM8 epitope was found only in association with root cap cell development at the root apex. Furthermore, the LM8 epitope is specifically...... associated with root cap cells in a range of angiosperm species. In embryogenic carrot suspension cell cultures the epitope is abundant at the surface of cell walls of loosely attached cells in both induced and non-induced cultures. The LM8 epitope is the first cell wall epitope to be identified...

  8. Detached-eddy simulations of hydrokinetic turbines using actuator disks

    Science.gov (United States)

    Sciolla, Domenico; Escauriaza, Cristian

    2012-11-01

    The development of new technologies to harness energy from tidal currents in coastal areas requires an understanding of the interaction of the flow over arbitrary bathymetries and the marine hydrokinetic (MHK) turbines that can be potentially installed at a specific site. When computing realistic flows past multiple MHK devices, numerical models should satisfy the following attributes: (1) Resolve the rich dynamics of the wakes to capture the instantaneous interactions of the turbulent coherent structures; (2) Deal with complex arbitrary bathymetries of the natural channels; and (3) Employ low-cost modeling techniques to incorporate the regions of interest with good resolution and multiple turbine arrangements. In this investigation we simulate the flow past porous disks using the detached-eddy simulation approach (DES). The results show that the model reproduces accurately the mean flow and turbulence statistics of the wakes, and constitutes a powerful tool for analyzing the flow field in realistic conditions using low computational resources. The simulation results are also employed to determine the forces induced by the turbine array on the entire flow, parameterizing its effects to be incorporated in regional-scale models. Support for this work has been provided by Fondef project D09I1052.

  9. Prevalence of posterior vitreous detachment in glaucoma patients and controls.

    Science.gov (United States)

    Schwab, Christoph; Glatz, Wilfried; Schmidt, Bernd; Lindner, Ewald; Oettl, Karl; Riedl, Regina; Wedrich, Andreas; Ivastinovic, Domagoj; Velikay-Parel, Michaela; Mossboeck, Georg

    2017-05-01

    To evaluate the impact of oxidative stress - present in glaucoma - on the vitreous. We therefore compare the presence of early and late stages of posterior vitreous detachment (PVD) between patients with glaucoma and controls. The vitreous state was evaluated by the combination of optical coherence tomography and ultrasound. The main outcome was the vitreous state classified into 'no PVD', 'initial PVD' and 'advanced PVD'. We evaluated the vitreous state in 48 patients with glaucoma (age: mean 66.5 ± 11.9 years; visual field deviation: mean 10.4 ± 6.8 dB) and compared the results with 101 previously investigated controls (age: mean 73.6 ± 9.3 years). After one-to-one matching on age and sex, ordinal logistic regression revealed that patients with glaucoma were significantly more likely to exhibit advanced PVD stages compared to non-glaucoma patients (OR 2.60, 95% confidence interval: 1.06-6.36, p = 0.037). Our results suggest that the presence or absence of PVD might be a valuable hint for diagnosing glaucoma - however, further research is needed to determine whether PVD can be used to supplement current glaucoma screening guidelines. © 2016 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  10. A DEEPLY ECLIPSING DETACHED DOUBLE HELIUM WHITE DWARF BINARY

    International Nuclear Information System (INIS)

    Parsons, S. G.; Marsh, T. R.; Gaensicke, B. T.; Drake, A. J.; Koester, D.

    2011-01-01

    Using Liverpool Telescope+RISE photometry we identify the 2.78 hr period binary star CSS 41177 as a detached eclipsing double white dwarf binary with a 21,100 K primary star and a 10,500 K secondary star. This makes CSS 41177 only the second known eclipsing double white dwarf binary after NLTT 11748. The 2 minute long primary eclipse is 40% deep and the secondary eclipse 10% deep. From Gemini+GMOS spectroscopy, we measure the radial velocities of both components of the binary from the Hα absorption line cores. These measurements, combined with the light curve information, yield white dwarf masses of M 1 = 0.283 ± 0.064 M sun and M 2 = 0.274 ± 0.034 M sun , making them both helium core white dwarfs. As an eclipsing, double-lined spectroscopic binary, CSS 41177 is ideally suited to measuring precise, model-independent masses and radii. The two white dwarfs will merge in roughly 1.1 Gyr to form a single sdB star.

  11. OUTCOMES OF RETINAL DETACHMENT REPAIR AFTER POSTERIOR OPEN GLOBE INJURY.

    Science.gov (United States)

    Reed, David C; Juhn, Alexander T; Rayess, Nadim; Hsu, Jason; Chiang, Allen

    2016-04-01

    To report outcomes of retinal detachment (RD) repair following posterior open globe injury. This retrospective, consecutive case series examined patients who underwent RD repair following Zone II and/or III open globe injury repair between January 1, 2007 and October 31, 2013. Patients with retina was achieved in 25 (83%) during the first vitreoretinal surgical procedure and 5 (17%) were deemed inoperable intraoperatively. Ten patients (30%) developed recurrent RD, and 8 underwent additional surgery. At last follow-up, reattachment was observed in 4 of these 8. The overall rate of final reattachment was 63% (19 patients). The mean number of surgeries for RD was 1.5 (range, 1-3). Fifteen patients (50%) achieved final visual acuity of counting fingers or better. Mean follow-up from the last vitreoretinal surgery was 23 months (range, 3-52). Although RD following posterior open globe injury confers a grave prognosis, successful anatomic reattachment of the retina was achieved in the majority of patients in this series, with half achieving ambulatory vision.

  12. Nerve growth factor helps protect retina in experimental retinal detachment.

    Science.gov (United States)

    Sun, Xiaodong; Xu, Xun; Wang, Fenghua; Zhang, Xi; Ho, Patrick C P; Liu, Haiyang; Qian, Jin; Yu, Zhang; Lu, Hongfen; Xu, Weiqi

    2008-01-01

    To investigate the expression of nerve growth factor (NGF) and its receptor TrkA on the retina at different time points after retinal detachment (RD) and the protection effect of NGF in experimental RD. Sprague-Dawley rats were used as an RD animal model by injection of 0.1% sodium hyaluronate under the neurosensory retina. The expression of endogenous NGF and its receptor TrkA in the rat retina was detected using immunohistochemistry. The NGF (5 mug/eye) or phosphate-buffered saline were injected separately into vitreous every 4 days after the RD. The rat eyes were then observed at various time points. Morphologic changes were investigated by light microscopy. Retinal gliosis was detected by glial fibrillary acidic protein labeling. The expression of endogenous NGF and TrkA was upregulated during RD procedure. Most of the NGF-treated retina had a well-organized structure. In NGF-treated RD eyes, the cells were still significantly more numerous than in phosphate-buffered-saline-treated retina. Glial fibrillary acidic protein labeling increased quickly after RD; the NGF-treated retina had less reactive gliosis than the control groups. Intravitreal injection of exogenous NGF can protect retinal cells from degeneration in experimental RD. It may exert its protective action by preventing the apoptosis of retinal cells after RD. (c) 2007 S. Karger AG, Basel.

  13. Success Rates of Vitrectomy in Treatment of Rhegmatogenous Retinal Detachment

    Directory of Open Access Journals (Sweden)

    Yasser Helmy Mohamed

    2016-01-01

    Full Text Available Aim. To investigate the anatomical success rates of pars plana vitrectomy (PPV after primary rhegmatogenous retinal detachment (RRD. Methods. This retrospective study was conducted between December 2008 and October 2014 at Nagasaki University Hospital. The preoperative data recorded included the lens status, location of the retinal tear, whether a tear was visualized, presence of multiple tears, macula status, presence of peripheral lattice retinal degeneration, and best-corrected visual acuity (BCVA. The primary outcome measures were anatomical (primary and final and functional success (visual acuity better than 6/60. Results. This study evaluated 422 eyes of 411 patients with a mean age of 57.7±11.2 years. The single-operation reattachment rate (primary anatomical success was 89.8%. The final anatomical success rate was 100% after 2–6 operations (mean = 3.14±1.03. Functional success rate after the primary reattachment operation was 96.7%, while it was 97.2% at the end of the follow-up. Multiple logistic regression analysis of the possible risk factors for the primary anatomical failure showed a significant relation with the 25 G instruments (P=0.002 and the presence of multiple tears (P=0.01. Conclusion. The primary anatomical success of PPV for primary uncomplicated RRD was 89.8% and the final anatomical success rate was 100%.

  14. Success Rates of Vitrectomy in Treatment of Rhegmatogenous Retinal Detachment.

    Science.gov (United States)

    Mohamed, Yasser Helmy; Ono, Kozue; Kinoshita, Hirofumi; Uematsu, Masafumi; Tsuiki, Eiko; Fujikawa, Azusa; Kitaoka, Takashi

    2016-01-01

    Aim. To investigate the anatomical success rates of pars plana vitrectomy (PPV) after primary rhegmatogenous retinal detachment (RRD). Methods. This retrospective study was conducted between December 2008 and October 2014 at Nagasaki University Hospital. The preoperative data recorded included the lens status, location of the retinal tear, whether a tear was visualized, presence of multiple tears, macula status, presence of peripheral lattice retinal degeneration, and best-corrected visual acuity (BCVA). The primary outcome measures were anatomical (primary and final) and functional success (visual acuity better than 6/60). Results. This study evaluated 422 eyes of 411 patients with a mean age of 57.7 ± 11.2 years. The single-operation reattachment rate (primary anatomical success) was 89.8%. The final anatomical success rate was 100% after 2-6 operations (mean = 3.14 ± 1.03). Functional success rate after the primary reattachment operation was 96.7%, while it was 97.2% at the end of the follow-up. Multiple logistic regression analysis of the possible risk factors for the primary anatomical failure showed a significant relation with the 25 G instruments (P = 0.002) and the presence of multiple tears (P = 0.01). Conclusion. The primary anatomical success of PPV for primary uncomplicated RRD was 89.8% and the final anatomical success rate was 100%.

  15. A Mathematical Model of Quorum Sensing Induced Biofilm Detachment.

    Science.gov (United States)

    Emerenini, Blessing O; Hense, Burkhard A; Kuttler, Christina; Eberl, Hermann J

    2015-01-01

    Cell dispersal (or detachment) is part of the developmental cycle of microbial biofilms. It can be externally or internally induced, and manifests itself in discrete sloughing events, whereby many cells disperse in an instance, or in continuous slower dispersal of single cells. One suggested trigger of cell dispersal is quorum sensing, a cell-cell communication mechanism used to coordinate gene expression and behavior in groups based on population densities. To better understand the interplay of colony growth and cell dispersal, we develop a dynamic, spatially extended mathematical model that includes biofilm growth, production of quorum sensing molecules, cell dispersal triggered by quorum sensing molecules, and re-attachment of cells. This is a highly nonlinear system of diffusion-reaction equations that we study in computer simulations. Our results show that quorum sensing induced cell dispersal can be an efficient mechanism for bacteria to control the size of a biofilm colony, and at the same time enhance its downstream colonization potential. In fact we find that over the lifetime of a biofilm colony the majority of cells produced are lost into the aqueous phase, supporting the notion of biofilms as cell nurseries. We find that a single quorum sensing based mechanism can explain both, discrete dispersal events and continuous shedding of cells from a colony. Moreover, quorum sensing induced cell dispersal affects the structure and architecture of the biofilm, for example it might lead to the formation of hollow inner regions in a biofilm colony.

  16. Documents and detachment in the figurational sociology of sport

    Directory of Open Access Journals (Sweden)

    Paddy Dolan

    2015-01-01

    Full Text Available This article discusses the methodological implications of using a figurational approach to the study of Gaelic games (the Irish sports of hurling and Gaelic football and their organisation and governance from the late nineteenth century onwards. Following Norbert Elias, we argue that data generation guided by theories, and potentially modifying such theories, are essential components of research endeavours. The problem of generalisation or representativeness of historical documents can be addressed by treating documents as part of a fi guration of evidence, thereby constituting a mutually supporting network of data that serves as a scaffold or structure for theoretical and empirical findings. Based on the experience of using documents such as newspaper and referee reports of matches, and also organisational documents such as the minutes of meetings at various levels of governance, we contribute to the discussion concerning borders and boundary maintenance between history, sociology and historical sociology. While we elaborate on the Eliasian perspective on emotional detachment, and secondary involvement, when conducting research, we also note the dificulties in avoiding ‘preferred’ readings of national history given that Gaelic games have been intertwined with the narrative and project of national self-determination in Ireland. Researchers are compelled to recognise the theoretical significance of sports as a motor and symbol of emotional identifications, but must also create distance from their own national habitus in order to prioritise participation in intergenerational knowledge generation over further national myth-making.

  17. Silicone oil removal after rhegmatogenous retinal detachment: comparing techniques.

    Science.gov (United States)

    Tan, H S; Dell'omo, R; Mura, M

    2012-03-01

    To assess the outcome of silicone oil removal after rhegmatogenous retinal detachment (RRD) surgery, and to compare results of a two-port (infusion-extraction) versus a three-port (full vitrectomy) approach. Primary outcome measure was the rate of redetachment. Secondary outcome measures were visual acuity, rate of intraoperative and postoperative epiretinal membrane removal and complications. We included 147 consecutive cases. There were 15 cases of giant retinal tear, 26 cases of RRD without proliferative vitreoretinopathy (PVR) and 106 cases of RRD with PVR. The overall redetachment rate after silicone oil removal was 17.7%. In the group treated with the two-port technique (n=95), the retina redetached in 16 cases (16.8%), and in the group treated with the three-port technique (n=52), redetachment occurred in 10 cases (19.2%). This difference was not statistically significant (P=0.717; χ (2)-test). There was a significantly higher redetachment rate in cases with a short oil tamponade duration of <2 months. We reconfirm a relatively high redetachment rate after silicone oil removal. The risk of redetachment is not lower with the three-port compared with the two-port approach.

  18. Basic physical processes and reduced models for plasma detachment

    Science.gov (United States)

    Stangeby, P. C.

    2018-04-01

    The divertor of a tokamak reactor will have to satisfy a number of critical constraints, the first of which is that the divertor targets not fail due to excessive heating or sputter-erosion. This paramount constraint of target survival defines the operating window for the principal plasma properties at the divertor target, the density n t and temperature, T t. In particular T et level of radiative cooling in the divertor, and (b) the ion flux to the target in the presence of volumetric loss of particles, momentum and power in the divertor. The 2 Point Model, 2PM, is a widely used analytic model for relating (T t, n t) to the controlling upstream conditions. The 2PM is derived here for various levels of complexity regarding the effects included. Analytic models of divertor detachment provide valuable insight and useful approximations, but more complete modeling requires the use of edge codes such as EDGE2D, SOLPS, SONIC, UEDGE, etc. Edge codes have grown to become quite sophisticated and now constitute, in effect, ‘code-experiments’ that—just as for actual experiments—can benefit from interpretation in terms of simple conceptual frameworks. 2 Point Model Formatting, 2PMF, of edge code output can provide such a conceptual framework. Methods of applying 2PMF are illustrated here with some examples.

  19. A 12 MINUTE ORBITAL PERIOD DETACHED WHITE DWARF ECLIPSING BINARY

    International Nuclear Information System (INIS)

    Brown, Warren R.; Kilic, Mukremin; Kenyon, Scott J.; Hermes, J. J.; Winget, D. E.; Prieto, Carlos Allende

    2011-01-01

    We have discovered a detached pair of white dwarfs (WDs) with a 12.75 minute orbital period and a 1315 km s -1 radial velocity amplitude. We measure the full orbital parameters of the system using its light curve, which shows ellipsoidal variations, Doppler boosting, and primary and secondary eclipses. The primary is a 0.25 M sun tidally distorted helium WD, only the second tidally distorted WD known. The unseen secondary is a 0.55 M sun carbon-oxygen WD. The two WDs will come into contact in 0.9 Myr due to loss of energy and angular momentum via gravitational wave radiation. Upon contact the systems may merge (yielding a rapidly spinning massive WD), form a stable interacting binary, or possibly explode as an underluminous Type Ia supernova. The system currently has a gravitational wave strain of 10 -22 , about 10,000 times larger than the Hulse-Taylor pulsar; this system would be detected by the proposed Laser Interferometer Space Antenna gravitational wave mission in the first week of operation. This system's rapid change in orbital period will provide a fundamental test of general relativity.

  20. Delayed Descemet's membrane detachment after successful cataract surgery: a case report

    Directory of Open Access Journals (Sweden)

    Aileen Walsh

    2012-10-01

    Full Text Available The detachment of Descemet's membrane can be a serious complication following cataract surgery, leading to severe corneal edema and reduced visual acuity. This report describes an unusual case of Descemet's membrane detachment 6 months after successful phacoemulsification, documented by anterior segment optic coherence tomography (OCT; RTVue, Optovue. The eye was treated successfully with pneumatic descemetopexy and transcorneal suturing, with reattachment of Descemet's membrane. This report should alert physicians that delayed corneal edema can be related to late-onset Descemet's membrane detachment, which requires proper treatment to avoid permanent corneal decompensation.

  1. Rhegmatogenous retinal detachment in an eye of retinoblastoma treated by radiation and cryocoagulation

    International Nuclear Information System (INIS)

    Inoue, Makoto; Tanaka, Yasuhiko; Kawai, Masataka; Nii, Seiji; Katsura, Hiroshi; Kaneko, Akihiro

    1999-01-01

    A 4-month-old female infant was diagnosed as bilateral retinoblastoma. The left eye was treated by enucleation and the right by radiation. The right eye received repeated thermochemotherapy, cryocoagulation and photocoagulation for recurrence. Total retinal detachment was detected after surgery for complicated cataract at the age of 2 years 9 months. Vitreous surgery led to the detection of posterior vitreous detachment and retinal breaks in the coagulated scar areas with vitreoretinal adhesion around the calcified tumor. During the following one year, the retina has been attached with no reoccurrence of the tumor. This case illustrates that rhegmatogenous retinal detachment is a possibility in retinoblastoma treated by radiation or retinal coagulations. (author)

  2. Rhegmatogenous retinal detachment in an eye of retinoblastoma treated by radiation and cryocoagulation

    Energy Technology Data Exchange (ETDEWEB)

    Inoue, Makoto; Tanaka, Yasuhiko; Kawai, Masataka; Nii, Seiji [Keio Univ., Tokyo (Japan). School of Medicine; Katsura, Hiroshi; Kaneko, Akihiro

    1999-08-01

    A 4-month-old female infant was diagnosed as bilateral retinoblastoma. The left eye was treated by enucleation and the right by radiation. The right eye received repeated thermochemotherapy, cryocoagulation and photocoagulation for recurrence. Total retinal detachment was detected after surgery for complicated cataract at the age of 2 years 9 months. Vitreous surgery led to the detection of posterior vitreous detachment and retinal breaks in the coagulated scar areas with vitreoretinal adhesion around the calcified tumor. During the following one year, the retina has been attached with no reoccurrence of the tumor. This case illustrates that rhegmatogenous retinal detachment is a possibility in retinoblastoma treated by radiation or retinal coagulations. (author)

  3. Reaction of wheat cultivars and differential lines to Puccinia triticina races in detached leaves

    Directory of Open Access Journals (Sweden)

    Camila Turra

    2014-12-01

    Full Text Available The method of preserving detached wheat leaves in Petri dish was used for the inoculation and development of the fungus Puccinia triticina, the causal agent of wheat leaf rust. The reaction of 26 wheat cultivars was compared by using seedlings cultivated in pots (in vivo and detached leaves (in vitro inoculated with four physiological races of the pathogen. After inoculation, the material was kept in a growth chamber for 15 days. The reaction was evaluated on the 15th day after inoculation. Results for each race in the evaluated genotypes confirmed the efficiency of the detached leaf method in assessing the reaction of wheat cultivars.

  4. Thermochemical Properties of Nicotine Salts

    Directory of Open Access Journals (Sweden)

    Riggs DM

    2014-12-01

    Full Text Available The thermal gravimetric analysis (TGA and differential scanning calorimetry (DSC results presented in this report clearly show that the thermal stability and the endothermic peak nicotine release temperatures are different for different nicotine salts and these temperatures appear to be linked to the general microstructural details of the salt itself. In addition, the peak nicotine release temperatures are highly dependent upon the sample size used. The heat of vaporization for neat (non-protonated nicotine is also sample-size dependent. The TGA data showed that the least stable of the salts tested at elevated temperatures was the liquid salt nicotine triacetate followed by the crystalline materials (e.g., nicotine gallate and finally, the amorphous salts (e.g., nicotine alginate. The DSC results revealed that the liquid and crystalline salts exhibit nicotine release endotherms that are strongly related to the sample weight being tested. The amorphous salts show nicotine endotherm peak temperatures that are nearly independent of the sample weight. The range of peak nicotine release temperatures varied depending upon the specific salts and the sample size from 83 oC to well over 200 oC. Based on these results, the evolution of nicotine from the nicotine salt should be expected to vary based on the composition of the salt, the details of its microstructure, and the amount of nicotine salt tested.

  5. Effect of basement structure and salt tectonics on deformation styles along strike: An example from the Kuqa fold-thrust belt, West China

    Science.gov (United States)

    Neng, Yuan; Xie, Huiwen; Yin, Hongwei; Li, Yong; Wang, Wei

    2018-04-01

    The Kuqa fold-thrust belt (KFTB) has a complex thrust-system geometry and comprises basement-involved thrusts, décollement thrusts, triangle zones, strike-slip faults, transpressional faults, and pop-up structures. These structures, combined with the effects of Paleogene salt tectonics and Paleozoic basement uplift form a complex structural zone trending E-W. Interpretation and comprehensive analysis of recent high-quality seismic data, field observations, boreholes, and gravity data covering the KFTB has been performed to understand the characteristics and mechanisms of the deformation styles along strike. Regional sections, fold-thrust system maps of the surface and the sub-salt layer, salt and basement structure distribution maps have been created, and a comprehensive analysis of thrust systems performed. The results indicate that the thrust-fold system in Paleogene salt range can be divided into five segments from east to west: the Kela-3, Keshen, Dabei, Bozi, and Awate segments. In the easternmost and westernmost parts of the Paleogene salt range, strike-slip faulting and basement-involved thrusting are the dominant deformation styles, as basement uplift and the limits of the Cenozoic evaporite deposit are the main controls on deformation. Salt-core detachment fold-thrust systems coincide with areas of salt tectonics, and pop-up, imbricate, and duplex structures are associated with the main thrust faults in the sub-salt layer. Distribution maps of thrust systems, basement structures, and salt tectonics show that Paleozoic basement uplift controlled the Paleozoic foreland basin morphology and the distribution of Cenozoic salt in the KFTB, and thus had a strong influence on the segmented structural deformation and evolution of the fold-thrust belt. Three types of transfer zone are identified, based on the characteristics of the salt layer and basement uplift, and the effects of these zones on the fault systems are evaluated. Basement uplift and the boundary of

  6. The material flow of salt

    International Nuclear Information System (INIS)

    Kostick, D.S.

    1993-01-01

    Salt (NaCl) is a universal mineral commodity used by virtually every person in the world. Although a very common mineral today, at one time it was considered as precious as gold in certain cultures. This study traces the material flow of salt from its origin through the postconsumer phase of usage. The final disposition of salt in the estimated 14,000 different uses, grouped into several macrocategories, is traced from the dispersive loss of salt into the environment to the ultimate disposal of salt-base products into the waste stream after consumption. The base year for this study is 1990, in which an estimated 196 million short tons of municipal solid waste was discarded by the US population. Approximately three-fourths of domestic salt consumed is released to the environment and unrecovered while about one-fourth is discharged to landfills and incinerators as products derived from salt. Cumulative historical domestic production, trade, and consumption data have been compiled to illustrate the long-term trends within the US salt industry and the cumulative contribution that highway deicing salt has had on the environment. Salt is an important component of drilling fluids in well drilling. It is used to flocculate and to increase the density of the drilling fluid in order to overcome high down-well gas pressures. Whenever drilling activities encounter salt formations, salt is added to the drilling fluid to saturate the solution and minimize the dissolution within the salt strata. Salt is also used to increase the set rate of concrete in cemented casings. This subsector includes companies engaged in oil, gas, and crude petroleum exploration and in refining and compounding lubricating oil. It includes SIC major groups 13 and 29. 13 refs., 14 figs., 6 tabs

  7. Recombination dominated hydrogenic emission from the detached plasmas in W7-AS

    International Nuclear Information System (INIS)

    Ramasubramanian, N.; Koenig, R.; Wenzel, U.; Thomsen, H.; McCormick, K.; Grigull, P.; Feng, Y.; Klinger, T.; John, A.

    2003-01-01

    Beyond a certain threshold average density in the High-Density H-Mode the island divertor plasma in the stellarator W7-AS undergoes partial detachment. The tomographic reconstruction of the radiated power density from the detached pulses show that the radiation profile in the triangular plane is also asymmetric. In the detached phase, the spectrometer viewing tangentially to the target tiles in the top divertor region manifests that the impurity radiation layer is close to the X-points. The spectral analysis also demonstrates the presence of a hydrogen radiation zone dominated by recombination emission close to the target tiles. This papers presents the emission from the deeply detached locations including the volume recombination in a stable discharge. (orig.)

  8. [Rhegmatogenous retinal detachment in a patient with previous penetrating keratoplasty (clinical case)].

    Science.gov (United States)

    Burcea, M; Muşat, O; Gheorghe, Andreea; Mahdi, Labib; Colta, Diana; Cernat, Corina; Mansour, Agajani

    2014-01-01

    We present the case of a 54 year old patient diagnosed with rhegmatogenous retinal detachment and perforating keratoplasty. Surgery is recommended and we performed posterior vitrectomy, endolaser, and internal heavy oil tamponade. The post-operative course was favorable.

  9. Multilayered pigment epithelial detachment in neovascular age-related macular degeneration

    DEFF Research Database (Denmark)

    Rahimy, Ehsan; Freund, K Bailey; Larsen, Michael

    2014-01-01

    PURPOSE: To describe the spectral domain optical coherence tomography findings in eyes with chronic fibrovascular pigment epithelial detachment (PED) receiving intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy. METHODS: Retrospective observational case series of patients...

  10. USE OF 25-GAUGE VITRECTOMY IN THE MANAGEMENT OF PRIMARY RHEGMATOGENOUS RETINAL DETACHMENT

    NARCIS (Netherlands)

    Mura, Marco; Tan, Stevie H.; de Smet, Marc D.

    2009-01-01

    Purpose: To evaluate the anatomical and functional results of 25-gauge transconjuctival vitrectomy in the management of primary rhegmatogenous retinal detachment (RRD). Methods: A retrospective, noncomparative interventional case series including 131 consecutive patients who underwent 25-gauge

  11. Salt supply to and significance of asymmetric salt diapirs

    DEFF Research Database (Denmark)

    Koyi, H.; Burliga, S.; Chemia, Zurab

    2012-01-01

    Salt diapirs can be asymmetric both internally and externally reflecting their evolution history. As such, this asymmetry bear a significant amount of information about the differential loading (± lateral forces) and in turn the salt supply that have shaped the diapir. In two dimensions...... southeastern overhang due to salt extrusion during Middle Cretaceous followed by its burial in Tertiary. This external asymmetry is also reflected in the internal configuration of the diapir which shows different rates of salt flow on the two halves of the structure. The asymmetric external and internal...... sediments, the diapir extruded an overhang. Using the asymmetric Klodawa Salt Structure (KSS) in central Poland as a prototype, a series of analogue models were carried out to investigate the evolution history and salt supply driven by asymmetric differential loading. During extension of the model, a daipir...

  12. Tamponade in surgery for retinal detachment associated with proliferative vitreoretinopathy.

    Science.gov (United States)

    Schwartz, Stephen G; Flynn, Harry W; Lee, Wen-Hsiang; Wang, Xue

    2014-02-14

    Retinal detachment (RD) with proliferative vitreoretinopathy (PVR) often requires surgery to restore normal anatomy and to stabilize or improve vision. PVR usually occurs in association with recurrent RD (that is, after initial retinal re-attachment surgery) but occasionally may be associated with primary RD. Either way, a tamponade agent (gas or silicone oil) is needed during surgery to reduce the rate of postoperative recurrent RD. The objective of this review was to assess the relative safety and effectiveness of various tamponade agents used with surgery for retinal detachment (RD) complicated by proliferative vitreoretinopathy (PVR). We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (The Cochrane Library 2013, Issue 5), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE (January 1946 to June 2013), EMBASE (January 1980 to June 2013), Latin American and Caribbean Literature on Health Sciences (LILACS) (January 1982 to June 2013), the metaRegister of Controlled Trials (mRCT) (www.controlled-trials.com), ClinicalTrials.gov (www.clinicaltrials.gov) and the WHO International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We did not use any date or language restrictions in the electronic searches for trials. We last searched the electronic databases on 26 June 2013. We included randomized controlled trials (RCTs) of participants undergoing surgery for RD associated with PVR that compared various tamponade agents. Two review authors screened the search results independently. We used the standard methodological procedures expected by The Cochrane Collaboration. The review included 516 participants from three RCTs. One study was conducted in the USA and consisted of two trials: the first trial randomized 151 adults to receive either silicone oil or sulfur hexafluoride (SF6) gas tamponades; and the second trial randomized 271 adults to receive either

  13. Persistent subretinal fluid due to central serous chorioretinopathy after retinal detachment surgery

    OpenAIRE

    Moreno-L?pez, Mar?a; P?rez-L?pez, Marta; Casas-Llera, Pilar; Jarr?n, Elena; Mu?oz-Negrete, Francisco Jos?

    2011-01-01

    María Moreno-López, Marta Pérez-López, Pilar Casas-Llera, Elena Jarrín, Francisco José Muñoz-NegreteOphthalmology Unit, Hospital Ramón y Cajal, Madrid, SpainBackground: The causes of persistent submacular detachment after successful rhegmatogenous retinal detachment (RRD) surgery remain unknown. Its presence is associated with poor postoperative visual acuity, but due to its spontaneous resolution no addit...

  14. Visualization of intermittent blobby plasma transport in attached and detached plasmas of the NAGDIS-II

    International Nuclear Information System (INIS)

    Ohno, Noriyasu; Furuta, Katsuhiro; Takamura, Shuichi

    2004-01-01

    We investigated the intermittent convective plasma transport in a attached and/or detached plasma condition of the linear divertor plasma simulator, NAGDIS-II. Images taken by a fast-imaging camera clearly show that in attached plasmas, blobs are peeled off the bulk plasma, and propagate outward with an azimuthal motion. In detached plasmas, plasma turbulence observed near the plasma recombining region drives strong intermittent radial plasma transport, which could broaden the radial density profile. (author)

  15. [Functional results of cryosurgical procedures in rhegmatogenous retinal detachment including macula region - our experience].

    Science.gov (United States)

    Chrapek, O; Sín, M; Jirková, B; Jarkovský, J; Rehák, J

    2013-10-01

    Aim of this study is to evaluate retrospectively functional results of cryosurgical treatment of uncomplicated, idiopathic rhegmatogenous retinal detachment including macula region in phakic patients operated on at the Department of Ophthalmology, Faculty Hospital, Palacký University, Olomouc, Czech Republic, E.U., during the period 2002 -2013, and to evaluate the significance of the macula detachment duration for the final visual acuity. In the study group were included 56 eyes of 56 patients operated in the years 2003 - 2012 at the Department of Ophthalmology, Faculty Hospital, Palacký University, Olomouc. All patients were phakic and in all of them, the retinal detachment including the macula region was diagnosed. The mean follow-up period of the patients was 8,75 months. The initial and final visual acuity testing were performed. Comparing the initial and final visual acuity we rated the level of the visual acuity change. The result was stated as improved, if the visual acuity improved by 1 or more lines on the ETDRS chart. The result was rated as stabilized, if the visual acuity remained the same or it changed by 1 line of the ETDRS chart only. The result was evaluated as worsened, if the visual acuity decreased by 1 or more lines of the ETDRS chart. In the followed-up group, the authors compared visual acuity levels in patients with the macula detachment duration 10 days and 11 days. For the statistical evaluation of achieved results, the Mann - Whitney U test was used. The visual acuity improved in 49 (87 %), did not changed in 5 (9 %) and worsened in 2 (4 %) patients. The patients with macula detachment duration 10 days achieved statistically significant better visual acuity than patients with macula detachment duration 11 days. Patients with macula detachment duration 10 days have better prognosis for functional result than patients with macula detachment duration 11 days.

  16. Inicial nasal mucosa detachment using piezoelectric device in the Le Fort I osteotomy: A technical note

    Directory of Open Access Journals (Sweden)

    Elio Hitoshi Shinohara

    2013-01-01

    Full Text Available In maxillary Le Fort I type osteotomy the detachment of the nasal mucosa should be done carefully. Piezoelectric surgery contributed much to increase the safety of osteotomies, despite the initial advantage of minimizing the risk of injury in nervous tissue, mainly in bilateral sagittal split osteotomy; we use the piezoelectric device for the initial detachment of the nasal mucosa in the maxillary osteotomy.

  17. Inicial nasal mucosa detachment using piezoelectric device in the Le Fort I osteotomy: A technical note

    Science.gov (United States)

    Shinohara, Elio Hitoshi; Kaba, Shajadi Carlos Pardo; Ruiz, Marcelo Martinson; Horikawa, Fernando Kendi

    2013-01-01

    In maxillary Le Fort I type osteotomy the detachment of the nasal mucosa should be done carefully. Piezoelectric surgery contributed much to increase the safety of osteotomies, despite the initial advantage of minimizing the risk of injury in nervous tissue, mainly in bilateral sagittal split osteotomy; we use the piezoelectric device for the initial detachment of the nasal mucosa in the maxillary osteotomy. PMID:23853472

  18. Retinal detachment and gyrate atrophy of the choroid and retina: case report.

    Science.gov (United States)

    Berbel, Rodrigo Fabri; Rauen, Paulo Igor; Pallone, Raphael Frangiote; Casella, Antônio Marcelo Barbante

    2012-01-01

    To report a case of gyrate atrophy of the choroid and retina associated with retinal detachment. Hyperornithinemia confirmed the diagnosis of gyrate atrophy. Pars plana vitrectomy with silicone oil infusion was performed with good anatomical results, despite the persistence of low visual acuity. Retinal detachment is a rare complication of gyrate atrophy and can be managed with pars plana vitrectomy and silicone oil. We discuss the possible mechanisms that led to low visual acuity.

  19. MRt in the recurrent retinal detachment diagnosis after intraocular tamponade media injection: state of the art

    International Nuclear Information System (INIS)

    Manfre, L.; Midiri, M.; Casto, A.; Angileri, T.; Cardinale, A.

    1994-01-01

    Inraocular Silicon (SO), Fluorosilicon (FSO) oil or Perfluorocarbon fluid (PFCL) injection is a new succesfull surgical technique in the treatment detachment. After personal casu istic review, we report our experience in 37 patients, who underwent pars plana vitrectomy with intraocular SO, FSO or PFCL in injection for retinal detachment, monitored with Magnetic Resonance Imaging controls. MRI, showing no significant oil-related artifcats, revealed as a confident, non-invasive imaging modality in evaluating patient undergone tamponade media intraocular injection

  20. Cyclic GMP in the pig vitreous and retina after experimental retinal detachment.

    Science.gov (United States)

    Diederen, Roselie M H; La Heij, Ellen C; Lemmens, Marijke A M; Kijlstra, Aize; de Vente, Jan; Hendrikse, Fred

    2008-02-04

    Earlier studies have revealed a decreased level of cGMP in vitreous fluid obtained from patients with a retinal detachment. To further investigate this phenomenon, we developed an experimental retinal detachment model in pigs. Experimental unilateral retinal detachments were induced in pig eyes by subretinal injection of 0.25% sodium hyaluronate. Fourteen days later the vitreous and retinas were analyzed for cGMP expression. Following enucleation, the retinas were incubated in the presence of a nonselective phosphodiesterase inhibitor (IBMX), and the particulate guanylyl cyclase stimulator atrial natriuretic peptide (ANP) or the soluble guanylyl cyclase stimulator sodium nitroprusside (SNP). cGMP was visualized in retinal wholemounts by immunochemistry combined with a computer based stereology system. cGMP levels in vitreous were determined by ELISA. The mean vitreous cGMP level in pig eyes with a retinal detachment (1.45 pmol/ml) was significantly lower compared to the mean level of cGMP in healthy pig eyes (4.61 pmol/ml; p=0.028 was considered significant). In the inner retina, ANP as well as SNP induced cGMP immunoreactivity in both detached and healthy retinas. After incubation with ANP, cGMP could also be detected in the outer nuclear layer of the detached retina, whereas this was not the case in the normal retina. Experimental retinal detachment in the pig eye leads to a decrease of cGMP levels in vitreous similar to that observed in clinical studies. This model may be helpful to analyze the mechanisms involved in cGMP dynamics following retinal detachment.

  1. Protein changes in the retina following experimental retinal detachment in rabbits.

    Science.gov (United States)

    Mandal, Nakul; Lewis, Geoffrey P; Fisher, Steven K; Heegaard, Steffen; Prause, Jan U; la Cour, Morten; Vorum, Henrik; Honoré, Bent

    2011-01-01

    Retinal detachment leads to the widespread cellular remodeling of the retina. The purpose of this study was to identify protein changes that accompany these cellular alterations by comparing the proteomic profiles of sham and experimentally detached rabbit retina. Elucidation of the proteins most dramatically affected by retinal detachment would add further understanding to the pathophysiology of this condition, and potentially identify therapeutic targets useful in preventing the deleterious effects of detachment, including photoreceptor cell death and the activation of non-neuronal microglial and Müller cells. Retinal detachments were induced in the right eyes of six New Zealand Red pigmented rabbits. Sham surgery was performed in the right eyes of six other rabbits that were used as controls. At seven days, the eyes were enucleated and the retinal tissue was harvested. The individual retinal samples were subjected to high resolution two-dimensional polyacrylamide gel electrophoresis. Differentially expressed protein spots were processed for identification by liquid chromatography-tandem mass spectrometry. Further investigation was undertaken with western blotting, and immunocytochemical studies on a further set of four sham and four detached retinas. Eighteen protein spots were found to be at least twofold differentially expressed between the sham and detached retinas. These protein spots were identified as: vimentin; tubulin β-2C; fragments of α-enolase; fructose-bisphosphate aldolase A; ATP synthase subunit β; mitochondrial creatine kinase; N-terminal fragments of albumin; prohibitin; and transducin-β(1). The differentially expressed proteins determined in this study may play an important role in the cellular responses of the retina after its detachment, subsequent ability to recover following surgical reattachment, as well as in serious complications such as subretinal fibrosis and proliferative vitreoretinopathy.

  2. Adoption, Cynical Detachment, and New Age Beliefs in Juno and Kung Fu Panda

    OpenAIRE

    Chen, Fu-jen

    2017-01-01

    In his article "Adoption, Cynical Detachment, and New Age Beliefs in Juno and Kung Fu Panda" Fu-Jen Chen situates his study within today's prevailing climate of global consumption to argue that the 2007 film Juno—featuring an unconventional portrayal of the adoption triad and a cynical detachment from public values—not only trivializes and depoliticizes the practice of adoption but also serves as an ideological supplement to today's global capitalism. Furthermore, Kung Fu Panda 1 & 2 (2008; 2...

  3. Where Does Road Salt Go - a Static Salt Model

    Science.gov (United States)

    Yu, C. W.; Liu, F.; Moriarty, V. W.

    2017-12-01

    Each winter, more than 15 million tons of road salt is applied in the United States for the de-icing purpose. Considerable amount of chloride in road salt flows into streams/drainage systems with the snow melt runoff and spring storms, and eventually goes into ecologically sensitive low-lying areas in the watershed, such as ponds and lakes. In many watersheds in the northern part of US, the chloride level in the water body has increased significantly in the past decades, and continues an upward trend. The environmental and ecological impact of the elevated chloride level can no longer be ignored. However although there are many studies on the biological impact of elevated chloride levels, there are few investigations on how the spatially distributed road salt application affects various parts of the watershed. In this presentation, we propose a static road salt model as a first-order metric to address spacial distribution of salt loading. Derived from the Topological Wetness Index (TWI) in many hydrological models, this static salt model provides a spatial impact as- sessment of road salt applications. To demonstrate the effectiveness of the static model, National Elevation Dataset (NED) of ten-meter resolution of Lake George watershed in New York State is used to generate the TWI, which is used to compute a spatially dis- tributed "salt-loading coefficient" of the whole watershed. Spatially varying salt applica- tion rate is then aggregated, using the salt-loading coefficients as weights, to provide salt loading assessments of streams in the watershed. Time-aggregated data from five CTD (conductivity-temperature-depth) sensors in selected streams are used for calibration. The model outputs and the sensor data demonstrate a strong linear correlation, with the R value of 0.97. The investigation shows that the static modeling approach may provide an effective method for the understanding the input and transport of road salt to within watersheds.

  4. Enzyme-free cell detachment mediated by resonance vibration with temperature modulation.

    Science.gov (United States)

    Kurashina, Yuta; Hirano, Makoto; Imashiro, Chikahiro; Totani, Kiichiro; Komotori, Jun; Takemura, Kenjiro

    2017-10-01

    Cell detachment is an essential process in adherent cell culture. However, trypsinization, which is the most popular detachment technique used in culture, damages cellular membranes. Reducing cellular membrane damage during detachment should improve the quality of cell culture. In this article, we propose an enzyme-free cell detachment method based on resonance vibration with temperature modulation. We developed a culture device that can excite a resonance vibration and control temperature. We then evaluated the cell detachment ratio and the growth response, observed the morphology, and analyzed the cellular protein of the collected cells-mouse myoblast cell line (C2C12). With the temperature of 10°C and the maximum vibration amplitude of 2 μm, 77.9% of cells in number were successfully detached compared with traditional trypsinization. The 72-h proliferation ratio of the reseeded cells was similar to that with trypsinization, whereas the proliferation ratio of proposed method was 12.6% greater than that of trypsinization after freezing and thawing. Moreover, the cells can be collected relatively intact and both intracellular and cell surface proteins in the proposed method were less damaged than in trypsinization. These results show that this method has definite advantages over trypsinization, which indicates that it could be applied to subcultures of cells that are more susceptible to trypsin damage for mass culture of sustainable clinical use. Biotechnol. Bioeng. 2017;114: 2279-2288. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  5. Postoperative recovery of visual function after macula-off rhegmatogenous retinal detachment.

    Science.gov (United States)

    van de Put, Mathijs A J; Croonen, Danna; Nolte, Ilja M; Japing, Wouter J; Hooymans, Johanna M M; Los, Leonoor I

    2014-01-01

    To determine which factors affect the recovery of visual function in macula off rhegmatogenous retinal detachment (RRD). In a prospective study of forty-five patients with a primary macula-off RRD of 24 hours to 6 weeks duration, the height of the macular detachment was determined by ultrasonography. At 12 months postoperatively, best corrected visual acuity (BCVA), contrast acuity, and color confusion indexes (CCI) were obtained. Macular detachment was present for 2-32 (median 7) days before repair. A shorter duration of macular detachment was correlated with a better CCI saturé (p = 0.0026) and lower LogMAR BCVA (better Snellen visual acuity) (p = 0.012). Also, a smaller height of macular detachment was correlated with a lower LogMAR BCVA (p = 0.0034). A younger age and lower pre-operative LogMAR BCVA at presentation were both correlated with better postoperative contrast acuity in the total group (age: p = 1.7×10(-4) and pre-operative LogMAR BCVA: p = 0.0034). Functional recovery after macula-off RRD is affected by the duration and the height of the macular detachment. Recovery of contrast acuity is also affected by age and BCVA at presentation. ARVO annual meeting 2013, May 7, Seattle, Washington, United States of America. trialregister.nl NTR839.

  6. [Clinical Characteristics of Rhegmatogenous Retinal Detachment in Highly Myopic and Phakic Eyes].

    Science.gov (United States)

    Orihara, Tadashi; Hirota, Kazunari; Yokota, Reiji; Kunita, Daisuke; Itoh, Yuji; Rii, Tosho; Koto, Takashi; Hiraoka, Tomoyuki; Inoue, Makoto; Hirakata, Akito

    2016-05-01

    To evaluate clinical characteristics of rhegmatogenous retinal detachment in high myopic and phakic eyes. The subjects were 1174 eyes of phakic rhegmatogenous retinal detachment detected in 1199 eyes that underwent initial vitreoretinal surgery between April 2006 and March 2011. Eyes with macular hole retinal detachment or secondary retinal detachment were excluded. The 486 eyes with high myopia (spherical equivalent ≤ -6.0 D or axial length ≥ 26.5 mm) and the 688 eyes with non-high myopia were compared. The mean age was significantly younger in the high myopia group (42.7 ± 14.2 years old, p lattice degeneration were more frequent (16.7%, 20.4%, respectively). The incidences of the retinal detachment in younger age and those caused by retinal holes were higher in the high myopia group. Higher incidence of retinal detachment and lattice degeneration in the fellow eyes of the high myopia group indicated that careful observation also in the fellow eyes was recommended.

  7. Middle Miocene E-W tectonic horst structure of Crete through extensional detachment faults

    International Nuclear Information System (INIS)

    Papanikolaou, D; Vassilakis, E

    2008-01-01

    Two east-west trending extensional detachment faults have been recognized in Crete, one with top-to-the-north motion of the hanging wall toward the Cretan Sea and one with top-to-the-south motion of the hanging wall toward the Libyan Sea. The east-west trending zone between these two detachment faults, which forms their common footwall, comprises a tectonic horst formed during Middle Miocene slip on the detachment faults. The detachment faults disrupt the overall tectono-stratigraphic succession of Crete and are localized along pre-existing thrust faults and along particular portions of the stratigraphic sequence, including the transition between the Permo-Triassic Tyros Beds and the base of the Upper Triassic-Eocene carbonate platform of the Tripolis nappe. By recognizing several different tectono-stratigraphic formations within what is generally termed the 'phyllite-quartzite', it is possible to distinguish these extensional detachment faults from thrust faults and minor discontinuities in the sequence. The deformation history of units within Crete can be summarized as: (i) compressional deformation producing arc-parallel east-west trending south-directed thrust faults in Oligocene to Early Miocene time (ii) extensional deformation along arc-parallel, east-west trending detachment faults in Middle Miocene time, with hanging wall motion to the north and south; (iii) Late Miocene-Quaternary extensional deformation along high-angle normal and oblique normal faults that disrupt the older arc-parallel structures

  8. Spontaneous Detachment of Colloids from Primary Energy Minima by Brownian Diffusion.

    Directory of Open Access Journals (Sweden)

    Zhan Wang

    Full Text Available The Derjaguin-Landau-Verwey-Overbeek (DLVO interaction energy profile has been frequently used to interpret the mechanisms controlling colloid attachment/detachment and aggregation/disaggregation behavior. This study highlighted a type of energy profile that is characterized by a shallow primary energy well (i.e., comparable to the average kinetic energy of a colloid at a small separation distance and a monotonic decrease of interaction energy with separation distance beyond the primary energy well. This energy profile is present due to variations of height, curvature, and density of discrete physical heterogeneities on collector surfaces. The energy profile indicates that colloids can be spontaneously detached from the shallow primary energy well by Brownian diffusion. The spontaneous detachment from primary minima was unambiguously confirmed by conducting laboratory column transport experiments involving flow interruptions for two model colloids (polystyrene latex microspheres and engineered nanoparticles (fullerene C60 aggregates. Whereas the spontaneous detachment has been frequently attributed to attachment in secondary minima in the literature, our study indicates that the detached colloids could be initially attached at primary minima. Our study further suggests that the spontaneous disaggregation from primary minima is more significant than spontaneous detachment because the primary minimum depth between colloid themselves is lower than that between a colloid and a collector surface.

  9. Spontaneous Detachment of Colloids from Primary Energy Minima by Brownian Diffusion.

    Science.gov (United States)

    Wang, Zhan; Jin, Yan; Shen, Chongyang; Li, Tiantian; Huang, Yuanfang; Li, Baoguo

    2016-01-01

    The Derjaguin-Landau-Verwey-Overbeek (DLVO) interaction energy profile has been frequently used to interpret the mechanisms controlling colloid attachment/detachment and aggregation/disaggregation behavior. This study highlighted a type of energy profile that is characterized by a shallow primary energy well (i.e., comparable to the average kinetic energy of a colloid) at a small separation distance and a monotonic decrease of interaction energy with separation distance beyond the primary energy well. This energy profile is present due to variations of height, curvature, and density of discrete physical heterogeneities on collector surfaces. The energy profile indicates that colloids can be spontaneously detached from the shallow primary energy well by Brownian diffusion. The spontaneous detachment from primary minima was unambiguously confirmed by conducting laboratory column transport experiments involving flow interruptions for two model colloids (polystyrene latex microspheres) and engineered nanoparticles (fullerene C60 aggregates). Whereas the spontaneous detachment has been frequently attributed to attachment in secondary minima in the literature, our study indicates that the detached colloids could be initially attached at primary minima. Our study further suggests that the spontaneous disaggregation from primary minima is more significant than spontaneous detachment because the primary minimum depth between colloid themselves is lower than that between a colloid and a collector surface.

  10. Long-term follow-up of patients after retinal detachment surgery.

    Science.gov (United States)

    Coakes, R L; Ramsay, J H; Tarbuck, D T

    1978-04-01

    The value of long-term follow-up of patients after retinal detachment surgery depends on the number of further detachments prevented. This in turn depends on the frequency with which predisposing lesions are found and treated and also the risk of leaving them untreated. In a retrospective study of 128 patients who had attended the Retina Clinic at Moorfields, High Holborn, for at least 10 years, the frequency with which asymptomatic retinal breaks were detected was less than two per hundred patients per year of follow-up. The risk of such lesions progressing to detachment if left untreated is estimated to be no more than 12 per cent and on this basis it is likely that no more than four or five detachments were prevented in our series. During the same period 66 new or re-detachments occurred, in spite of regular examination and treatment of predisposing lesions found, and it is concluded that long-term follow-up is of doubtful value in the prevention of further detachments.

  11. Postoperative recovery of visual function after macula-off rhegmatogenous retinal detachment.

    Directory of Open Access Journals (Sweden)

    Mathijs A J van de Put

    Full Text Available PURPOSE: To determine which factors affect the recovery of visual function in macula off rhegmatogenous retinal detachment (RRD. METHODS: In a prospective study of forty-five patients with a primary macula-off RRD of 24 hours to 6 weeks duration, the height of the macular detachment was determined by ultrasonography. At 12 months postoperatively, best corrected visual acuity (BCVA, contrast acuity, and color confusion indexes (CCI were obtained. RESULTS: Macular detachment was present for 2-32 (median 7 days before repair. A shorter duration of macular detachment was correlated with a better CCI saturé (p = 0.0026 and lower LogMAR BCVA (better Snellen visual acuity (p = 0.012. Also, a smaller height of macular detachment was correlated with a lower LogMAR BCVA (p = 0.0034. A younger age and lower pre-operative LogMAR BCVA at presentation were both correlated with better postoperative contrast acuity in the total group (age: p = 1.7×10(-4 and pre-operative LogMAR BCVA: p = 0.0034. CONCLUSION: Functional recovery after macula-off RRD is affected by the duration and the height of the macular detachment. Recovery of contrast acuity is also affected by age and BCVA at presentation. MEETING PRESENTATION: ARVO annual meeting 2013, May 7, Seattle, Washington, United States of America. TRIAL REGISTRATION: trialregister.nl NTR839.

  12. Reactive halogen species above salt lakes and salt pans

    OpenAIRE

    Holla, Robert

    2013-01-01

    Salt lakes can be found on all continents and saline soils cover 2.5% of the land surface of the earth (FAO, 2012). This thesis investigates the presence of reactive halogen species (RHS) above salt lakes and saline soils to evaluate their relevance for tropospheric chemistry of the planetary boundary layer. Ground-based MAX-DOAS and LP-DOAS measurements were conducted at salt lakes and two other sites with high halogen content. Prior to this work, RHS were found at three salt ...

  13. Rheology of rock salt for salt tectonics modeling

    Directory of Open Access Journals (Sweden)

    Shi-Yuan Li

    2016-10-01

    Full Text Available Abstract Numerical modeling of salt tectonics is a rapidly evolving field; however, the constitutive equations to model long-term rock salt rheology in nature still remain controversial. Firstly, we built a database about the strain rate versus the differential stress through collecting the data from salt creep experiments at a range of temperatures (20–200 °C in laboratories. The aim is to collect data about salt deformation in nature, and the flow properties can be extracted from the data in laboratory experiments. Moreover, as an important preparation for salt tectonics modeling, a numerical model based on creep experiments of rock salt was developed in order to verify the specific model using the Abaqus package. Finally, under the condition of low differential stresses, the deformation mechanism would be extrapolated and discussed according to microstructure research. Since the studies of salt deformation in nature are the reliable extrapolation of laboratory data, we simplified the rock salt rheology to dislocation creep corresponding to power law creep (n = 5 with the appropriate material parameters in the salt tectonic modeling.

  14. Electrolyte salts for nonaqueous electrolytes

    Science.gov (United States)

    Amine, Khalil; Zhang, Zhengcheng; Chen, Zonghai

    2012-10-09

    Metal complex salts may be used in lithium ion batteries. Such metal complex salts not only perform as an electrolyte salt in a lithium ion batteries with high solubility and conductivity, but also can act as redox shuttles that provide overcharge protection of individual cells in a battery pack and/or as electrolyte additives to provide other mechanisms to provide overcharge protection to lithium ion batteries. The metal complex salts have at least one aromatic ring. The aromatic moiety may be reversibly oxidized/reduced at a potential slightly higher than the working potential of the positive electrode in the lithium ion battery. The metal complex salts may also be known as overcharge protection salts.

  15. Salt fluoridation and oral health

    Directory of Open Access Journals (Sweden)

    Thomas M. Marthaler

    2013-11-01

    Full Text Available The aim of this paper is to make known the potential of fluoridated salt in community oral health programs, particularly in South Eastern Europe. Since 1922, the addition of iodine to salt has been successful in Switzerland. Goiter is virtually extinct. By 1945, the cariesprotective effect of fluorides was well established. Based on the success of water fluoridation, a gynecologist started adding of fluoride to salt. The sale of fluoridated salt began in 1956 in the Swiss Canton of Zurich, and several other cantons followed suit. Studies initiated in the early seventies showed that fluoride, when added to salt, inhibits dental caries. The addition of fluoride to salt for human consumption was officially authorized in 1980-82. In Switzerland 85% of domestic salt consumed is fluoridated and 67% in Germany. Salt fluoridation schemes are reaching more than one hundred million in Mexico, Colombia, Peru and Cuba. The cost of salt fluoridation is very low, within 0.02 and 0.05 € per year and capita. Children and adults of the low socio-economic strata tend to have substantially more untreated caries than higher strata. Salt fluoridation is by far the cheapest method for improving oral health. Conclusions. Salt fluoridation has cariostatic potential like water fluoridation (caries reductions up to 50%. In Europe, meaningful percentages of users have been attained only in Germany (67% and Switzerland (85%. In Latin America, there are more than 100 million users, and several countries have arrived at coverage of 90 to 99%. Salt fluoridation is by far the cheapest method of caries prevention, and billions of people throughout the world could benefit from this method.

  16. Salt fluoridation and oral health.

    Science.gov (United States)

    Marthaler, Thomas M

    2013-11-01

    The aim of this paper is to make known the potential of fluoridated salt in community oral health programs, particularly in South Eastern Europe. Since 1922, the addition of iodine to salt has been successful in Switzerland. Goiter is virtually extinct. By 1945, the caries-protective effect of fluorides was well established. Based on the success of water fluoridation, a gynecologist started adding of fluoride to salt. The sale of fluoridated salt began in 1956 in the Swiss Canton of Zurich, and several other cantons followed suit. Studies initiated in the early seventies showed that fluoride, when added to salt, inhibits dental caries. The addition of fluoride to salt for human consumption was officially authorized in 1980-82. In Switzerland 85% of domestic salt consumed is fluoridated and 67% in Germany. Salt fluoridation schemes are reaching more than one hundred million in Mexico, Colombia, Peru and Cuba. The cost of salt fluoridation is very low, within 0.02 and 0.05 € per year and capita. Children and adults of the low socio-economic strata tend to have substantially more untreated caries than higher strata. Salt fluoridation is by far the cheapest method for improving oral health. Salt fluoridation has cariostatic potential like water fluoridation (caries reductions up to 50%). In Europe, meaningful percentages of users have been attained only in Germany (67%) and Switzerland (85%). In Latin America, there are more than 100 million users, and several countries have arrived at coverage of 90 to 99%. Salt fluoridation is by far the cheapest method of caries prevention, and billions of people throughout the world could benefit from this method. Copyright © 2013 by Academy of Sciences and Arts of Bosnia and Herzegovina.

  17. Salt, caprock, and sheath study

    International Nuclear Information System (INIS)

    Karably, L.S. Jr.; Jernigan, B.L.; Petre, I.C.; Sullivan, J.M.

    1983-01-01

    Salt domes of the Gulf Coast region of the United States consist of four component parts: 1) a salt stock, 2) caprock material, 3) sheath material, and 4) the surrounding upturned sediments. Salt stock consists of remarkably pure halite (NaCl), which represents 90 to 99% of the total mass, with the major impurity being anhydrite. Salt stocks are markedly homogeneous and continuous with respect to composition, texture and structure. Caprock consists primarily of anhydrite, gypsum and calcite which commonly occur in monomineralic zones oriented roughly parallel to the top of the salt stock. Caprock composition varies markedly over any single salt stock as well as from one salt stock to another. Fracturing, porosity and permeability of caprock material are correspondingly variable, but are usually developed tto a higher degree in the upper portions of caprock; porosity and permeability may also be relatively high at the caprock-salt interface. Caprock is generally believed to form by residual accumulation of anhydrite from the dissolution of salt, with subsequent alteration of the anhydrite to calcite and gypsum. Sheath material, probably a mixture of sedimentary rocks (clastic and evaporite), formed as a result of mechanical interaction between the salt stock and surrounding sediments during diapirism. Sheath material is thought to be distributed throughout an external zone, consisting mainly of disturbed sediment, and an internal zone, consisting mainly of disturbed salt. Sheath material forms along a roughly cylindrical shear zone which encloses thesalt stock. Sheath material may be overpressured and is generally thought to be impermeable. Upturned sediments around the salt diapirs are the result of dome genesis; hovever, these sedimentary beds and other structures are beyond the scope of this report

  18. Detached Concern of Forensic Mental Health Nurses in Therapeutic Relationships With Patients: The Application of the Early Recognition Method Related to Detached Concern

    NARCIS (Netherlands)

    Fluttert, F.A.J.; Meijel, B.K.G. van; Nijman, H.L.I.; Björkly, S.; Grypdonck, M.H.F.

    2010-01-01

    Objective - Improvement of the interaction between forensic mental health nurses and patients may lead to a reduction of inpatient violence. The concept under study is detached concern, which refers to nurses' skills to neutralize the emotional appeal of patients by a balanced attitude between

  19. Exploring Salt Tectonics in Northern Pakistan using InSAR and Seismic Interpretations

    Science.gov (United States)

    Ahmad Abir, I.; Khan, S. D.; Bendick, R. O.; Qadir, A.; Tariq, S.

    2012-12-01

    Salt tectonics in Northern Pakistan affects the geological structures and the seismology of the area. Salt layers are important in influencing the deformation style of geological structures. The difference in deformation intensity between the Potwar Plateau-Salt Range and the Kohat Plateau-Surghar Range systems is attributed to the presence of a Pre-Cambrian salt layer. Overburden will slide efficiently on the ductile salt detachment and will result in low internal deformation, which is evident in the Potwar Plateau-Salt Range system. In this system, the salt layers act as a lubricant between the overlying sedimentary layers and the basement rocks. In contrast, the Kohat Plateau-Surghar Range system has high internal deformation. This could be due to the absence or the thinning of the salt layers which causes increase friction between the overburden and the basement rocks. Furthermore, north of the Main Boundary Thrust (MBT) fault system, where the area is believed to be locked due to the absence or thinning of the salt layer, strain could be accumulating and a potentially huge earthquake could occur. This is significant as the area include three major populated cities, which are Islamabad, Peshawar and Rawalpindi with over 4.1 million in population. This study is an attempt to investigate the role of salt in the geological deformation of the Salt Range-Potwar Plateau using InSAR and 2-D seismic interpretations. The extent and the structures of the Pre-Cambrian salt layer are mapped by interpreting 2D seismic sections. 2-D migrated seismic lines crossing the MBT and several lines located near central Salt Range were obtained. The top of the salt layer can be distinguished easily, as well as the overlying sedimentary sequence. Moreover, published velocity models of Salt Range were used to assist in the interpretation of the seismic sections. Exposed salt layers were mapped using published geological maps of the area. The Salt Range area is highly faulted with thrust

  20. Zechstein salt Denmark. Vol. 1

    International Nuclear Information System (INIS)

    Lyngsie Jacobsen, F.; Soenderholm, M.; Springer, N.; Gutzon Larsen, J.; Lagoni, P.; Fabricius, J.

    1984-01-01

    The Salt Research Project EFP-81 has mainly been aiming upon an elucidation of the stratigraphy of the Danish Zechstein evaporites. Also an attempt to clarify the connection between the fabric and the strength of the strongly deformed domal rock salt is performed. The unravelling of the stratigraphy is carried out by means of renewed interpretations of new and old data from all the wells drilling in the Danish Permian basin in connection with a revaluation of the core descriptions. By means of trace elements analysis it is possible to some extent to distinguish between Zestein 1 and 2 ''grey salt''. A description of the transition zone between Zechstein 1 and 2 is carried out. New methods of fabric analyses are introduced and the strength measurements of the rock salt are treated statistically in connection with new defined rock salt parameters. An investigation of fluid inclusions in halite and quartz crystals from dome salt has resulted in the determination of salinity and chemical composition of the brines present in the salt. Temperatures and corresponding pressures during the evolution of the salt pillow and salt dome have been established. The dehydration conditions of natural carnallite in situ are clarified. (author)

  1. Salt formations offer disposal alternative

    International Nuclear Information System (INIS)

    Funderburk, R.

    1990-01-01

    This paper discusses how three U.S. firms are spending millions to permit and build underground disposal sites in salt formations. These companies claim salt is the ideal geological medium for holding hazardous wastes. Two Texas locations and one in Michigan have been targeted as future sites for hazardous waste disposal. The Michigan site, outside Detroit, is a former salt mine 2,000 feet beneath the Ford Motor Co. (Detroit) assembly works in Dearborn. Both Texas sites are atop salt domes---one east and one west of Houston

  2. Pathophysiology of salt sensitivity hypertension.

    Science.gov (United States)

    Ando, Katsuyuki; Fujita, Toshiro

    2012-06-01

    Dietary salt intake is the most important factor contributing to hypertension, but the salt susceptibility of blood pressure (BP) is different in individual subjects. Although the pathogenesis of salt-sensitive hypertension is heterogeneous, it is mainly attributable to an impaired renal capacity to excrete sodium (Na(+) ). We recently identified two novel mechanisms that impair renal Na(+) -excreting function and result in an increase in BP. First, mineralocorticoid receptor (MR) activation in the kidney, which facilitates distal Na(+) reabsorption through epithelial Na(+) channel activation, causes salt-sensitive hypertension. This mechanism exists not only in models of high-aldosterone hypertension as seen in conditions of obesity or metabolic syndrome, but also in normal- or low-aldosterone type of salt-sensitive hypertension. In the latter, Rac1 activation by salt excess causes MR stimulation. Second, renospecific sympathoactivation may cause an increase in BP under conditions of salt excess. Renal beta2 adrenoceptor stimulation in the kidney leads to decreased transcription of the gene encoding WNK4, a negative regulator of Na(+) reabsorption through Na(+) -Cl (-) cotransporter in the distal convoluted tubules, resulting in salt-dependent hypertension. Abnormalities identified in these two pathways of Na(+) reabsorption in the distal nephron may present therapeutic targets for the treatment of salt-sensitive hypertension.

  3. Effect of rheological approximations on slab detachment in 3D numerical simulations of continental collision

    Science.gov (United States)

    Pusok, Adina E.; Kaus, Boris; Popov, Anton

    2017-04-01

    It is commonly accepted that slab detachment results from the development of extensional stresses within the subducting slab. Subduction slowdown due to arrival of buoyant continental material at the trench is considered to cause such stress build up in the slab. Following slab detachment, slab pull partially or completely loses its strength and hot asthenosphere may flow through the slab window, which can have major consequences for continental collision. The dynamics of slab detachment has been extensively studied in 2D (i.e. analytical and numerical), but 3D models of slab detachment during continental collision remain largely unexplored. Some of the previous 3D models have investigated the role of an asymmetric margin on the propagation of slab detachment (van Hunen and Allen, 2011), the impact of slab detachment on the curvature of orogenic belts (Capitanio and Replumaz, 2013), the role of the collision rate on slab detachment depth (Li et al., 2013) or the effect of along-trench variations on slab detachment (Duretz et al., 2014). However, rheology of mantle and lithosphere is known to have a major influence on the dynamics of subduction. Here, we explore a range of different rheological approximations to understand their sensitivity on the possible scenarios. We employ the code LaMEM (Kaus et al., 2016) to perform 3D simulations of subduction/continental collision in an integrated lithospheric and upper-mantle scale model. The models exhibit a wide range of behaviours depending on the rheological law employed: from linear, to temperature-dependent visco-elasto-plastic rheology that takes into account both diffusion and dislocation creep. For example, we find that slab dynamics varies drastically between end member models: in viscous approximations, slab detachment is slow, dominated by viscous thinning, while for a non-linear visco-elasto-plastic rheology, slab detachment is relatively fast, dominated by plastic breaking and inducing strong mantle flow in

  4. The Frequency of Serous Macular Detachment in Diabetic Macular Edema

    Directory of Open Access Journals (Sweden)

    Onur Yaya

    2015-05-01

    Full Text Available Objectives: To investigate the epidemiology and frequency of serous macular detachment (SMD in patients diagnosed with diabetic macular edema (DME. Materials and Methods: Hundred and forty-three eyes of 104 patients with DME were examined retrospectively. According to the results of OCT, the patients were separated into two groups; patients diagnosed with SMD and DME (group 1 and patients diagnosed with DME (group 2. They were assessed based on demographic characteristics, average age, duration of diabetes mellitus (DM, hypertension (HT history, best-corrected visual acuity, and diabetic retinopathy stages. Results: The average age of the patients was 61±8.7 years. Forty-three patients (41.3% were female and 61 patients (58.7% were male. Fifty-four of 104 patients (51.9% had DME with SMD. 21 (38.8% patients had bilateral SMD. In group 1, 31 patients were male (57.4% and 23 patients were female (42.6%. In group 2, 30 (60% patients were male and 20 (40% patients were female. In group 1, average age was 60.2±9.6 and the average duration of DM was 12.2±7.0 years, whereas the average age was 61.9±7.6 and the average duration of DM was 14.06±6.8 years in group 2. Forty-two patients in group 1 (77.8% and 30 patients (60% in group 2 had history of HT. Before the treatment, the average best-corrected visual acuity was found to be 0.30±0.24 in group 1 and 0.32±0.25 in group 2. Conclusion: Today, it is thought that diabetic maculopathy is the leading cause of SMD and it is a determining factor of treatment applications. In our study, we aimed at investigating the frequency of SMD in DME and the risk factors for the development of SMD. Although there were some differences between the factors, only the history of HT was found statistically higher in patients with SMD (p=0.04. (Turk J Ophthalmol 2015; 45: 92-96

  5. Association Between Oral Fluoroquinolone Use and Retinal Detachment.

    Science.gov (United States)

    Raguideau, Fanny; Lemaitre, Magali; Dray-Spira, Rosemary; Zureik, Mahmoud

    2016-04-01

    Several studies have focused on the current use of oral fluoroquinolones and the risk for retinal detachment (RD), but the existence of this association is under debate. Given the widespread fluoroquinolone use, investigation of this association is essential. To assess the association between oral fluoroquinolone use and the risk for RD, including the rhegmatogenous and exudative types. This case-crossover study included 27,540 adults with RD from French health care databases from July 1, 2010, through December 31, 2013. Patients with a history of RD or retinal break, endophthalmitis, intravitreal injection, choroidal retinal vitreal biopsy, and human immunodeficiency virus infection or those hospitalized within 6 months of RD were excluded. The risk period of primary interest was current use, defined as exposure to fluoroquinolones within 10 days immediately before RD surgery, according to previous findings. Oral fluoroquinolone use was assumed to start on the day the prescription was dispensed. Exposure to fluoroquinolones during the risk period (1-10 days) compared with the control period (61-180 days). The association was also assessed regarding use in the recent (11-30 days) and past (31-60 days) intermediate risk period, type of fluoroquinolone, and type of RD. Of the 27,540 eligible patients (57% men; mean [SD] age, 61.5 [13.6] years), 663 patients with RD were exposed to fluoroquinolones during the observation period, corresponding to 80 cases exposed during the 10-day risk period (≤10 days before RD) and 583 cases exposed during the control period (61-180 days). We found a significant increased risk for RD during the 10-day period after the dispensing of oral fluoroquinolones, with an adjusted odds ratio of 1.46 (95% CI, 1.15-1.87). The risk was significantly increased for rhegmatogenous and exudative RD, with adjusted odds ratios of 1.41 (95% CI, 1.04-1.92) and 2.57 (95% CI, 1.46-4.53), respectively. Recent and past use of fluoroquinolones were not

  6. Fused salt electrolysis

    International Nuclear Information System (INIS)

    Ares, Osvaldo; Botbol, Jose.

    1989-01-01

    Working conditions for zirconium preparation by fused salt electrolysis were studied. For such purpose, a cell was built for operation under argon atmosphere. A graphite crucible served as anode, with steel cathodes. Proper design allowed cathode rechange under the inert atmosphere. Cathodic deposits of zirconium powder occluded salts from the bath. After washing with both water and hydrochloric acid, the metallic powder was consolidated by fusion. Optimum operating conditions were found to arise from an electrolyte of 12% potassium hexafluorzirconate -88% sodium chloride, at 820 deg C and 5 A/cm 2 cathodic current density. Deposits contained 35% of metal and current efficiency reached 66%. The powder contained up to 600 ppm of chlorine and 1.700 ppm of fluorine; after fusion, those amounts decreased to 2 ppm and 3 ppm respectively, with low proportion of metallic impurities. Though oxygen proportion was 4.500 ppm, it should be lowered by improving working conditions, as well as working on an ampler scale. (Author)

  7. Early activation of inflammation- and immune response-related genes after experimental detachment of the porcine retina.

    Science.gov (United States)

    Hollborn, Margrit; Francke, Mike; Iandiev, Ianors; Bühner, Eva; Foja, Christian; Kohen, Leon; Reichenbach, Andreas; Wiedemann, Peter; Bringmann, Andreas; Uhlmann, Susann

    2008-03-01

    To determine early alterations in retinal gene expression in a porcine model of rhegmatogenous retinal detachment. Local detachment was created in eyes of adult pigs by subretinal application of sodium hyaluronate. The gene expression in control tissues and retinas detached for 24 hours was analyzed with a pig genome microarray. Genes with at least three-fold expression changes were detected in the detached retina and in the attached retinal tissue surrounding the local detachment in situ. Structural alterations of the retina were examined by light and electron microscopy. Identified were 85 genes that were upregulated and 7 that were downregulated in the detached retina. Twenty-eight genes were identified as upregulated in the nondetached retina of the surgical eyes. The genes upregulated in detached retinas were related to inflammation and immune responses (n = 52), antioxidants and metal homeostasis (n = 7), intracellular proteolysis (n = 6), and blood coagulation/fibrinolysis (n = 4). The upregulation of at least 15 interferon-stimulated genes indicates elevated interferon levels after detachment. Gene expression of blue-sensitive opsin was not detectable in the detached retinal tissue, suggesting an early reduction in phototransduction, especially in blue cones. Electron microscopy revealed an accumulation of microglial cells in the inner retinal tissue and of polymorphonuclear leukocytes in the vessels of detached and peridetached retinas. Differentially expressed genes in the retina early after experimental detachment are mainly related to inflammation and immune responses, intracellular proteolysis, and protection against oxidative stress. A local immune and inflammatory response may represent a major causative factor for reactive changes in the retina after detachment. The inflammatory response is not restricted to the detached retina but is also observed in the nondetached retina; this response may underlie functional changes in these regions described in

  8. Experiments in connection with Salt Domes

    NARCIS (Netherlands)

    Escher, B.G.; Kuenen, Ph.H.

    1928-01-01

    The different theories concerning the origin of Salt Domes in Roumania, Germany, Texas, Louisiana, Colorado and Utah are discussed. In Roumania the salt occurs in cores of “Diapir” anticlines. The existance of hills of salt indicates, that the salt is still pushing upwards. In Germany the salt

  9. Theory Of Salt Effects On Protein Solubility

    Science.gov (United States)

    Dahal, Yuba; Schmit, Jeremy

    Salt is one of the major factors that effects protein solubility. Often, at low salt concentration regime, protein solubility increases with the salt concentration(salting in) whereas at high salt concentration regime, solubility decreases with the increase in salt concentration(salting out). There are no quantitative theories to explain salting in and salting out. We have developed a model to describe the salting in and salting out. Our model accounts for the electrostatic Coulomb energy, salt entropy and non-electrostatic interaction between proteins. We analytically solve the linearized Poisson Boltzmann equation modelling the protein charge by a first order multipole expansion. In our model, protein charges are modulated by the anion binding. Consideration of only the zeroth order term in protein charge doesn't help to describe salting in phenomenon because of the repulsive interaction. To capture the salting in behaviour, it requires an attractive electrostatic interaction in low salt regime. Our work shows that at low salt concentration, dipole interaction is the cause for salting in and at high salt concentration a salt-dependent depletion interaction dominates and gives the salting out. Our theoretical result is consistent with the experimental result for Chymosin protein NIH Grant No R01GM107487.

  10. On the use of purchased fuelwood in detached houses in Finland

    International Nuclear Information System (INIS)

    Tuomi, S.; Mattila, K.

    1996-01-01

    The study, conducted jointly by the Finnish Forest Research Institute (METLA) and the Work Efficiency Institute (TTS-Institute), looked into the volumes of fuelwood consumed by, the manner of fuel wood procurement employed, and the usage plans of people living in detached houses. The study was conducted during the heating season 1992/93. METLA collected the study material by the means of a nation-wide mail inquiry. The base population for the study was provided by all the 1.4 million detached houses in Finland. The sample comprised 12 273 detached houses. This publication of the Forestry Department of TTS-Institute is a separate report on the use of fuelwood and other issues related to purchased fuelwood. An estimated total of 5.6 million m 3 of fuelwood were consumed in by household living in detached houses throughout Finland during the heating season 1992/93. The consumption of fuelwood on farms was 2.5 million m 3 , in detached houses proper 2.3 million m 3 , in recreational homes 0.6 million m 3 , and other houses 0.2 million m 3 . 3.6 million m 3 of the fuelwood consumed was acquired from the users' own woodlots. The proportion of purchased wood was nearly a million m 3 and another million m 3 of fuelwood were acquired by some other way. Of the purchased fuelwood, 12 % was bought ready- chopped. More than one owner of detached houses considered the use of purchased wood a possibility. Ready-chopped firewood was the most popular form of fuelwood. The owners of nearly 220 000 detached houses planned to increase their fuelwood consumption during the next two years and 27 % of them intended to buy their fuelwood. 11 % of the respondents were of the opinion that there was not enough purchased fuelwood in suitable form available in their locality. (19 refs.)

  11. Correlation of visual recovery with macular height in macula-off retinal detachments.

    Science.gov (United States)

    Mowatt, L; Tarin, S; Nair, R G; Menon, J; Price, N J

    2010-02-01

    To determine the relationship between the preoperative macular height of a macular detachment and visual outcome of the post retinal reattachment. Prospective case series of 26 patients who presented to the Wolverhampton Eye Infirmary with a primary rhegmatogenous macula-off retinal detachment. Macular detachment height was assessed by B-scan ultrasound (10 Mhz) in the seated and supine postures before surgery. Age, gender, duration of the detachment, type of surgery, preoperative (pre-op) and postoperative (post-op) visual acuities at 3 and 6 months and status of the fellow eye were noted. A total of 26 eyes of 26 patients (mean age: 61.4 years+/-15.56 SD) were recruited. The mean logMAR pre- and post-op visual acuities at 3 and 6 months were 1.5+/-1.1 SD (range: 0.2-3), 0.38+/-0.23 SD (range: 0-0.84), and at 6 months 0.29+/-0.22 SD (range: 0-1.0). The median period of the macular detachment was 4.5 days (95% CI: 2-8 days). There was no significant difference between the mean macular heights while seated 2.42 mm+/-1.2 or supine 2.39 mm+/-1.0 (t-test, P=0.9). Correlation showed that the pre-op macular height is a statistical predictor of post-op visual acuity in our group of patients with macula-off retinal detachments. The shallower the macular detachment the greater the likelihood of a good visual outcome.

  12. Unwanted detachment of the Solitaire device during mechanical thrombectomy in acute ischemic stroke.

    Science.gov (United States)

    Castaño, C; Dorado, L; Remollo, S; García-Bermejo, P; Gomis, M; Pérez de la Ossa, N; Millán, M; García-Sort, M R; Hidalgo, C; López-Cancio, E; Cubells, C; Dávalos, A

    2016-01-27

    The use of retrievable stents for endovascular clot retrieval has dramatically improved successful revascularization and clinical outcome in selected patients with acute stroke. To describe the rate and clinical consequences of unwanted spontaneous detachment of these devices during mechanical thrombectomy. We studied 262 consecutive patients treated with the retrievable stent, Solitaire, for acute ischemic stroke between November 2008 and April 2015. Clinical, procedural, and outcome variables were compared between patients with and without unexpected detachment of this device. Detachment was classified as proximal to the stent proximal marker (type A) or distal to the marker (type B). Poor functional outcome was defined as modified Rankin scale score >2 at 90 days. Unwanted detachment occurred in 6/262 (2.3%) cases, four of type A and two of type B. Stent recovery was possible in three patients, all of 'type A', but in none of 'type B'. The number of prior passes was higher in patients with undesired detachment (3 (2-5) vs 2 (1-3), p=0.007). Detachment was associated with higher rate of symptomatic intracranial hemorrhage (SICH) (33.3% vs 4.3%, p=0.001), poorer outcome (100% vs 54.8%, p=0.028), and higher mortality rate at 90 days (50% vs 17%, p=0.038). Unwanted detachment of a Solitaire is an uncommon complication during mechanical thrombectomy in patients with acute ischemic stroke and is associated with the clot retrieval attempts, SICH, poor outcome, and higher mortality. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  13. Prophylactic treatment of the fellow eye of patients with retinal detachment: a retrospective study.

    Science.gov (United States)

    Avitabile, Teresio; Bonfiglio, Vincenza; Reibaldi, Michele; Torrisi, Benedetto; Reibaldi, Alfredo

    2004-03-01

    Controversy exists over the prophylactic treatment of predisposing lesions to prevent retinal detachment. Seven hundred sixty consecutive phakic fellow eyes with rhegmatogenous retinal detachment in the first eye were examined by the same vitreoretinal surgeon before detachment surgery and for a follow-up period ranging from 1 to 72 months, with a mean of 36 months. During this period, in 305 fellow eyes (40.1%) predisposing retinal lesions were present and prophylactic treatments (photocoagulation, cryotherapy or scleral buckle) were performed independently of vitreous status. The results were then compared with the incidence of bilateral RD without prophylaxis reported in Folk and Burton's study of 1982; the two study's data were well matched and showed no significant difference in regards to age, sex, incidence myopia > or =-2.5 and incidence of lattice degeneration. The objective was to investigate whether or not prophylactic treatment is able to avert retinal detachment in the fellow eye. The age of the patients with peripheral retinal lesions was correlated inversely with the presence of myopia. Nine eyes out of 305 eyes treated (2.9%) developed a retinal detachment, reducing the rate of bilateral retinal detachment to 1.2% (9 eyes out of 760). This incidence of bilaterality (1.2%) was lower than the incidence of retinal detachment in fellow eyes not prophylactically treated as reported in the literature, and there exists a highly statistically significant difference between this study's data of 1.2% after prophylaxis and a 13.4% rate of bilaterality as reported by Folk without prophylaxis (P=0.0000).

  14. Caenorhabditis elegans response to salt

    NARCIS (Netherlands)

    O.O. Umuerri (Oluwatoroti Omowayewa)

    2012-01-01

    textabstractThis thesis describes my work, where I used genetic methods to identify new genes involved in salt taste in C. elegans. In addition, I used calcium imaging to characterize the cellular response of C. elegans to salt. The thesis is divided into five sections and each section is summarized

  15. The Salt II Treaty

    International Nuclear Information System (INIS)

    Caldwell, D.

    1991-01-01

    The first strategic arms limitation talks resulted in two agreements: the Anti-Ballistic Missile Treaty and the Interim Agreement to Limit Strategic Offensive Arms. Senator Henry M. (Scoop) Jackson (D-Wa.) was concerned about the numerical advantage granted to the USSR by the Latter agreement and proposed an amendment that would prohibit future negotiators from granting the Soviet Union similar terms. This paper discusses the second round of SALT negotiations which opened in November 1972 and continued under presidents Richard M. Nixon, Gerald Ford, and Jimmy Carter. As the negotiators met, U.S. and Soviet scientists and engineers continued their work to develop new nuclear weapons and launchers. Particularly problematic were modern, large ballistic missiles, cruise missiles, and the Soviet Backfire bomber

  16. Salt resistant crop plants

    KAUST Repository

    Roy, Stuart J.

    2014-04-01

    Soil salinity is a major constraint to agriculture. To improve salinity tolerance of crops, various traits can be incorporated, including ion exclusion, osmotic tolerance and tissue tolerance. We review the roles of a range of genes involved in salt tolerance traits. Different tissues and cells are adapted for specific and often diverse function, so it is important to express the genes in specific cell-types and to pyramid a range of traits. Modern biotechnology (marker- assisted selection or genetic engineering) needs to be increasingly used to introduce the correct combination of genes into elite crop cultivars. Importantly, the effects of introduced genes need to be evaluated in the field to determine their effect on salinity tolerance and yield improvement.

  17. The Relationship between Job Demands and Employees’ Counterproductive Work Behaviors: The Mediating Effect of Psychological Detachment and Job Anxiety

    Science.gov (United States)

    Chen, Yang; Li, Shuang; Xia, Qing; He, Chao

    2017-01-01

    This study aims to explore the relation between job demands and counterproductive work behaviors (CWBs). A cross-sectional sample of 439 coal miners completed a self-report questionnaire that assessed their job demands, psychological detachment, job anxiety, and CWBs in a Chinese context. The conceptual model, based on the stressor-detachment model, was examined using structural equation modeling. The results suggest that psychological detachment mediates not only the relation between job demands and job anxiety but also that between job demands and CWBs. Furthermore, the relation between job demands and CWBs is sequentially mediated by psychological detachment and job anxiety. Our findings validate the effectiveness of the stressor-detachment model. Moreover, we demonstrate that the underlying mechanism of the relation between job demands and CWBs can be explained by psychological detachment and job anxiety. PMID:29163274

  18. The Relationship between Job Demands and Employees' Counterproductive Work Behaviors: The Mediating Effect of Psychological Detachment and Job Anxiety.

    Science.gov (United States)

    Chen, Yang; Li, Shuang; Xia, Qing; He, Chao

    2017-01-01

    This study aims to explore the relation between job demands and counterproductive work behaviors (CWBs). A cross-sectional sample of 439 coal miners completed a self-report questionnaire that assessed their job demands, psychological detachment, job anxiety, and CWBs in a Chinese context. The conceptual model, based on the stressor-detachment model, was examined using structural equation modeling. The results suggest that psychological detachment mediates not only the relation between job demands and job anxiety but also that between job demands and CWBs. Furthermore, the relation between job demands and CWBs is sequentially mediated by psychological detachment and job anxiety. Our findings validate the effectiveness of the stressor-detachment model. Moreover, we demonstrate that the underlying mechanism of the relation between job demands and CWBs can be explained by psychological detachment and job anxiety.

  19. Persistent subretinal fluid due to central serous chorioretinopathy after retinal detachment surgery

    Directory of Open Access Journals (Sweden)

    Moreno-López M

    2011-10-01

    Full Text Available María Moreno-López, Marta Pérez-López, Pilar Casas-Llera, Elena Jarrín, Francisco José Muñoz-NegreteOphthalmology Unit, Hospital Ramón y Cajal, Madrid, SpainBackground: The causes of persistent submacular detachment after successful rhegmatogenous retinal detachment (RRD surgery remain unknown. Its presence is associated with poor postoperative visual acuity, but due to its spontaneous resolution no additional therapeutic or diagnostic procedure is recommended.Case report: A case of central serous chorioretinopathy (CSC that simulated persistent subfoveal fluid after RRD surgery is presented.Conclusion: To the authors' knowledge, no other case of visual impairment after successful retinal detachment surgery due to CSC has been reported in the PubMed database. In view of this report, CSC should be considered in the differential diagnosis of persistent subretinal fluid after successful retinal detachment surgery.Keywords: persistent subretinal fluid, retinal detachment surgery, central serous chorioretinopathy, vitrectomy

  20. Electron-detachment cross sections of halogen negative-ion projectiles for inertial confinement fusion

    Science.gov (United States)

    Sant'Anna, M. M.; Zappa, F.; Santos, A. C. F.; de Barros, A. L. F.; Wolff, W.; Coelho, L. F. S.; de Castro Faria, N. V.

    2004-07-01

    Negative-ion beams have recently been suggested as sources of high-energy heavy atoms to be used as drivers for inertial confinement fusion (ICF). Owing to their electron affinities limited to a few eV, anions can be efficiently photo-detached in the vicinity of the fusion chamber, with the resulting high-velocity neutral projectiles following ballistic trajectories towards the hydrogen pellet target. Electron-detachment cross sections are needed as parameters to estimate the beam attenuation in the path from the ion source to the hydrogen pellet. Halogen anions are possible projectile choices. In this paper we present experimental data for total electron-detachment cross sections for F-, Cl-, Br- and I- ions incident on N2, in the 0.94-74 keV u-1 energy range. Our measurements can benchmark theory on anion electron detachment at intermediate to high velocities. Comparison between different projectiles shows very similar collision velocity dependencies. A simple geometrical scaling is presented, providing an estimate for electron-detachment cross sections at the MeV u-1 energy range. The presented scaling indicates that the vacuum requirements due to the use of halogen anions for ICF are less critical than previously suggested.

  1. Electron-detachment cross sections of halogen negative-ion projectiles for inertial confinement fusion

    International Nuclear Information System (INIS)

    Sant'Anna, M M; Zappa, F; Santos, A C F; Barros, A L F de; Wolff, W; Coelho, L F S; Faria, N V de Castro

    2004-01-01

    Negative-ion beams have recently been suggested as sources of high-energy heavy atoms to be used as drivers for inertial confinement fusion (ICF). Owing to their electron affinities limited to a few eV, anions can be efficiently photo-detached in the vicinity of the fusion chamber, with the resulting high-velocity neutral projectiles following ballistic trajectories towards the hydrogen pellet target. Electron-detachment cross sections are needed as parameters to estimate the beam attenuation in the path from the ion source to the hydrogen pellet. Halogen anions are possible projectile choices. In this paper we present experimental data for total electron-detachment cross sections for F - , Cl - , Br - and I - ions incident on N 2 , in the 0.94-74 keV u -1 energy range. Our measurements can benchmark theory on anion electron detachment at intermediate to high velocities. Comparison between different projectiles shows very similar collision velocity dependencies. A simple geometrical scaling is presented, providing an estimate for electron-detachment cross sections at the MeV u -1 energy range. The presented scaling indicates that the vacuum requirements due to the use of halogen anions for ICF are less critical than previously suggested

  2. Return to work and risk of subsequent detachment from employment after myocardial infarction

    DEFF Research Database (Denmark)

    Smedegaard, Laerke; Numé, Anna Karin; Charlot, Mette

    2017-01-01

    Background--Limited data are available on return to work and subsequent detachment from employment after admission for myocardial infarction (MI). Methods and Results--Using individual-level linkage of data from nationwide registries, we identified patients of working age (30-65 years) discharged......--Despite that most patients returned to work after first-time MI, about 1 in 4 was detached from employment after 1 year. Several factors including age and lower socioeconomic status were associated with risk of detachment from employment.......Background--Limited data are available on return to work and subsequent detachment from employment after admission for myocardial infarction (MI). Methods and Results--Using individual-level linkage of data from nationwide registries, we identified patients of working age (30-65 years) discharged...... after first-time MI in the period 1997 to 2012, who were employed before admission. To assess the cumulative incidence of return to work and detachment from employment, the Aalen Johansen estimator was used. Incidences were compared with population controls matched on age and sex. Logistic regression...

  3. Topographic changes of retinal layers after resolution of acute retinal detachment.

    Science.gov (United States)

    Kim, Jae Hui; Park, Do Young; Ha, Hyo Shin; Kang, Se Woong

    2012-10-23

    To investigate changes in thickness profiles of retinal layers after resolution of recent onset rhegmatogenous retinal detachment Spectral domain optical coherence tomography (SD-OCT) scans were performed for 28 patients diagnosed with unilateral inferior half or superior half retinal detachment who underwent retinal reattachment surgery. The thickness of each retinal layer was measured at 3000 μm and 2800 μm in the superior and inferior directions from the foveal center. The thicknesses of each retinal layer of the reattached retina were compared with those of the undetached region of the retina of the same eye. Sixteen patients were diagnosed with superior half and 12 patients were diagnosed with inferior half retinal detachment. The mean duration of retinal detachment was 6.9 ± 3.9 days. SD-OCT scans were performed 10.4 ± 6.9 months after the surgery. The thicknesses of the outer nuclear layer and photoreceptor layer in the reattached retina were significantly thinner than those of the undetached retina (P = 0.012, and P = 0.018, respectively). Our findings suggest that prominent retinal structural sequelae, especially in outer nuclear layer and photoreceptor layer, can be induced by a short duration of retinal detachment. Our findings also underscore the important role of initial retinal injuries that occur within the first several days on the long term structural prognosis. (ClinicalTrials.gov number, NCT01587794).

  4. The fellow eye in patients with unilateral retinal detachment: findings and prophylactic treatment.

    Science.gov (United States)

    Laatikainen, L

    1985-10-01

    During a 4-year period, 1978-1981, 312 patients were operated on for unilateral rhegmatogenous detachment of the retina. Of the fellow eyes, 11% showed moderate (VA 0.15-0.4) and 5% severe (VA less than or equal to 0.1) visual impairment. Of the fellow eyes 49% were myopic (- 1.0 D. or more), and aphakia was present in 14%. Details of the peripheral fundus were adequately recordable for 260 fellow eyes. Degenerations considered to predispose to retinal detachment were found in 98 eyes (38%): lattice degeneration in 54 (21%), granular tuft in 17 (7%), retinal tear(s) in 12 (5%), and retinoschisis in 15 (6%). Prophylactic treatment of predisposing degenerations was performed in 91 of the 98 eyes using cryo- or photocoagulation (argon laser). No intra- or permanent post-operative complications were noticed. One of the treated fellow eyes (1.1%) detached 10 months after prophylactic treatment due to new tears. In the untreated group, 6 of the 221 eyes detached (2.7%). The difference was not statistically significant, but the groups were not comparable because 93% of the eyes showing predisposing degenerations were treated. None of the eyes treated for retinal breaks or lattice degeneration has detached. In these cases prophylactic treatment of the fellow eye is recommended. In most eyes cryocoagulation seems to be preferable to photocoagulation.

  5. Early rhegmatogenous retinal detachment following laser in situ keratomileusis for high myopia.

    Science.gov (United States)

    Farah, M E; Höfling-Lima, A L; Nascimento, E

    2000-01-01

    Four eyes had early rhegmatogenous retinal detachment within 3 months of laser in situ keratomileusis (LASIK) for correction of high myopia using the microkeratome, Clear Corneal Molder. In two eyes, retinal detachment resulted from horseshoe tears, one occurring in an otherwise normal region of the retina and the other at the margin of an area of lattice degeneration detected during preoperative examination. The first eye was treated with retinopexy using a 287 encircling scleral exoplant, drainage of subretinal fluid, and laser photocoagulation by indirect ophthalmoscopy. The other eye was treated with pneumatic retinopexy and cryotherapy. In the other eyes, retinal detachment was the result of giant tears with no evidence of prior retinal degeneration. These eyes were treated with pars plana vitrectomy, fluid-gas exchange with 15% perfluoropropane (C3F8), endolaser photocoagulation, and a 42 encircling scleral exoplant. After treatment, the first two eyes achieved spectacle-corrected visual acuity of 20/40. In the last two eyes, final spectacle-corrected visual acuity was 20/400 in one eye and light perception in the other. Although no cause-effect relationship between LASIK and retinal detachment can be stated, these cases suggest that LASIK may be associated with retinal detachment, particularly in highly myopic eyes. Further studies are necessary to determine high-risk patient characteristics.

  6. Retinal detachment repair and cataract surgery in patients with atopic dermatitis.

    Science.gov (United States)

    Gnana Jothi, V; McGimpsey, S; Sharkey, J A; Chan, W C

    2017-09-01

    PurposeThe aim of this study is to report a case series of ocular complications including retinal detachment (RD) and cataract in atopic dermatitis (AD) and surgical management involving a majority of Caucasian patients.Patients and methodsThis study is an observational case series, originally designed as an audit. It involves detailed discussion of history, clinical features, and surgical management of patients presenting with retinal detachment and cataracts secondary to severe AD. Six consecutive patients with diagnosis of severe AD requiring posterior segment and cataract surgery were included in the study.ResultsEight eyes of six patients had retinal detachment. Most of them involved the temporal retina. The retinal breaks were located anteriorly close to the ora serrata in six eyes and Giant tear retinal (GRT) detachment was found in two eyes. Five eyes had proliferative vitreo-retinopathy (PVR) at presentation. All six patients had bilateral cataracts and cataract surgery was performed in eleven eyes. Bilateral simultaneous surgery was essential in two patients. Three eyes had secondary intra-ocular lens (IOL) implantation with pars plana vitrectomy for subluxed lens implant.ConclusionsAnterior retinal breaks and temporal RD are common in retinal detachment secondary to AD. PVR is often present, which makes surgical management difficult. Cataract formation is quite often and late subluxation of IOL may occur.

  7. Bilateral Patching in Retinal Detachment: Fluid Mechanics and Retinal “Settling”

    Science.gov (United States)

    2011-01-01

    Purpose. When a patient suffers a retinal detachment and surgery is delayed, it is known clinically that bilaterally patching the patient may allow the retina to partially reattach or “settle.” Although this procedure has been performed since the 1860s, there is still debate as to how such a maneuver facilitates the reattachment of the retina. Methods. Finite element calculations using commercially available analysis software are used to elucidate the influence of reduction in eye movement caused by bilateral patching on the flow of subretinal fluid in a physical model of retinal detachment. Results. It was found that by coupling fluid mechanics with structural mechanics, a physically consistent explanation of increased retinal detachment with eye movements can be found in the case of traction on the retinal hole. Large eye movements increase vitreous traction and detachment forces on the edge of the retinal hole, creating a subretinal vacuum and facilitating increased subretinal fluid. Alternative models, in which intraocular fluid flow is redirected into the subretinal space, are not consistent with these simulations. Conclusions. The results of these simulations explain the physical principles behind bilateral patching and provide insight that can be used clinically. In particular, as is known clinically, bilateral patching may facilitate a decrease in the height of a retinal detachment. The results described here provide a description of a physical mechanism underlying this technique. The findings of this study may aid in deciding whether to bilaterally patch patients and in counseling patients on pre- and postoperative care. PMID:21666245

  8. The Relationship between Job Demands and Employees’ Counterproductive Work Behaviors: The Mediating Effect of Psychological Detachment and Job Anxiety

    OpenAIRE

    Chen, Yang; Li, Shuang; Xia, Qing; He, Chao

    2017-01-01

    This study aims to explore the relation between job demands and counterproductive work behaviors (CWBs). A cross-sectional sample of 439 coal miners completed a self-report questionnaire that assessed their job demands, psychological detachment, job anxiety, and CWBs in a Chinese context. The conceptual model, based on the stressor-detachment model, was examined using structural equation modeling. The results suggest that psychological detachment mediates not only the relation between job dem...

  9. Detachment of secondary dendrite arm in a directionally solidified Sn-Ni peritectic alloy under deceleration growth condition

    Science.gov (United States)

    Peng, Peng; Li, Xinzhong; Li, Jiangong; Su, Yanqing; Guo, Jingjie; Fu, Hengzhi

    2016-06-01

    In order to better understand the detachment mechanism of secondary dendrite arm during peritectic solidification, the detachment of secondary dendrite arm from the primary dendrite arms in directionally solidified Sn-36at.%Ni peritectic alloys is investigated at different deceleration rates. Extensive detachment of secondary dendrite arms from primary stem is observed below peritectic reaction temperature TP. And an analytical model is established to characterize the detachment process in terms of the secondary dendrite arm spacing λ2, the root radius of detached arms and the specific surface area (SV) of dendrites. It is found that the detachment mechanism is caused by not only curvature difference between the tips and roots of secondary branches, but also that between the thicker secondary branches and the thinner ones. Besides, this detachment process is significantly accelerated by the temperature gradient zone melting (TGZM) effect during peritectic solidification. It is demonstrated that the reaction constant (f) which is used to characterize the kinetics of peritectic reaction is crucial for the determination of the detachment process. The value of f not only changes with growth rate but also with solidification time at a given deceleration rate. In conclusion, these findings help the better understanding of the detachment mechanism.

  10. MACULAR BUCKLING WITH ANDO PLOMBE MAY INCREASE CHOROIDAL THICKNESS AND MIMIC SEROUS RETINAL DETACHMENT SEEN IN THE TILTED DISK SYNDROME.

    Science.gov (United States)

    Mateo, Carlos; Burés-Jelstrup, Anniken

    2016-01-01

    Serous subfoveal detachment has been described in the literature as a complication that appears at the border of the staphyloma. Macular buckling induces a postoperative inward bulge that resembles the ridge of a staphyloma. We describe three patients who developed a serous subfoveal detachment after uneventful macular buckling. To our knowledge, this complication, that shares similarities with the staphyloma ridge detachment, has not been previously reported. The clinical records of all cases that underwent macular buckling at our clinic were reviewed. Three patients developed a serous subfoveal detachment that could not be explained by choroidal neovascularization or polypoidal vascular choroidopathy. Along with the development of the subfoveal detachment, we observed an increase of the choroidal thickness beneath the fovea. This thickening, that tended to progress during the follow-up, resolved spontaneously after explantation of the buckle. The decrease in foveal thickness did also lead to resolution of the subfoveal detachment. The development of the subfoveal detachment in our patients was closely associated with a focal increase of the choroidal thickness after the macular buckling. After the buckle was removed, the choroidal thickness went back to the normal prebuckling values and the detachment resolved in all three patients. This leads us to think that there is a close association between choroidal thickness and the serous subfoveal detachment.

  11. The role of streptokinase in induction of posterior vitreous detachment: a scanning and transmission electron microscopic study of the retina in rabbits.

    Science.gov (United States)

    El Baha, Samir Mohammed; Abou-Nazel, Maha Wagdy; Idriss, Hesham Farouk; Abdel-Megeed, Ashraf Saad

    2003-10-01

    To evaluate the possibility of inducing a posterior vitreous detachment (PVD) by intravitreal injection of streptokinase using electron microscopy and electrophysiological study. The current study was performed on 30 eyes of 15 male white rabbits. The rabbits were divided into three equal groups. The right eye of the three groups received an intravitreal injection of streptokinase at three different concentrations (150, 1,500 and 15,000 IU in 0.1 mL balanced salt solution) in the mid vitreous cavity. The left eye in all animals received an intravitreal injection of balanced salt solution and was considered the control group. Electroretinography was performed 1 day and 1 week after injection. The rabbits were killed after 10 days, and the enucleated eyes were processed for transmission and scanning electron microscopic examination. In Group 1, scanning electron microscopy showed the retinal surface covered with thin collagen fibers, whereas in Group 2, a complete PVD with bare retinal surface was seen. Group 3 showed a bare retinal surface with hemorrhagic reaction and toxic effects on the retina by transmission electron microscopy. An intravitreal injection of 1,500 IU of streptokinase can lead to a PVD without major toxic effects on the retina.

  12. Iodized Salt Sales in the United States

    Directory of Open Access Journals (Sweden)

    Joyce Maalouf

    2015-03-01

    Full Text Available Iodized salt has been an important source of dietary iodine, a trace element important for regulating human growth, development, and metabolic functions. This analysis identified iodized table salt sales as a percentage of retail salt sales using Nielsen ScanTrack. We identified 1117 salt products, including 701 salt blends and 416 other salt products, 57 of which were iodized. When weighted by sales volume in ounces or per item, 53% contained iodized salt. These findings may provide a baseline for future monitoring of sales of iodized salt.

  13. Farallon slab detachment and deformation of the Magdalena Shelf, southern Baja California

    Science.gov (United States)

    Brothers, Daniel S.; Harding, Alistair J.; Gonzalez-Fernandez, Antonio; Holbrook, W.S. Steven; Kent, Graham M.; Driscoll, Neal W.; Fletcher, John M.; Lizarralde, Daniel; Umhoefer, Paul J.; Axen, Gary

    2012-01-01

    Subduction of the Farallon plate beneath northwestern Mexico stalled by ~12 Ma when the Pacific-Farallon spreading-ridge approached the subduction zone. Coupling between remnant slab and the overriding North American plate played an important role in the capture of the Baja California (BC) microplate by the Pacific Plate. Active-source seismic reflection and wide-angle seismic refraction profiles across southwestern BC (~24.5°N) are used to image the extent of remnant slab and study its impact on the overriding plate. We infer that the hot, buoyant slab detached ~40 km landward of the fossil trench. Isostatic rebound following slab detachment uplifted the margin and exposed the Magdalena Shelf to wave-base erosion. Subsequent cooling, subsidence and transtensional opening along the shelf (starting ~8 Ma) starved the fossil trench of terrigenous sediment input. Slab detachment and the resultant rebound of the margin provide a mechanism for rapid uplift and exhumation of forearc subduction complexes.

  14. Management of retinal detachment in block related globe perforation with pneumatic retinopexy

    Directory of Open Access Journals (Sweden)

    Karandeep Rishi

    2013-01-01

    Full Text Available Retinal detachment after ocular perforation related to local anesthesia is a common complication, which is usually associated with a poor prognosis despite complex vitreoretinal surgical procedures. We report a case of 62-year-old male with cataract surgery done 4 weeks back with nasal retinal detachment with a posterior break. Pneumatic retinopexy was performed and laser barrage of the breaks was done the next day when the retina got attached. A vision of 20/30 was achieved at the end of 2 months. To the best of our knowledge, this is a first case report in literature where pneumatic retinopexy was used to manage a retinal detachment caused by block-related perforation.

  15. Highly efficient subcloning of rodent malaria parasites by injection of single merosomes or detached cells.

    Science.gov (United States)

    Stanway, Rebecca R; Graewe, Stefanie; Rennenberg, Annika; Helm, Susanne; Heussler, Volker T

    2009-01-01

    This protocol describes a method for obtaining rodent Plasmodium parasite clones with high efficiency, which takes advantage of the normal course of Plasmodium in vitro exoerythrocytic development. At the completion of development, detached cells/merosomes form, which contain hundreds to thousands of merozoites. As all parasites within a single detached cell/merosome derive from the same sporozoite, we predicted them to be genetically identical. To prove this, hepatoma cells were infected simultaneously with a mixture of Plasmodium berghei sporozoites expressing either GFP or mCherry. Subsequently, individual detached cells/merosomes from this mixed population were selected and injected into mice, resulting in clonal blood stage parasite infections. Importantly, as a large majority of mice become successfully infected using this protocol, significantly less mice are necessary than for the widely used technique of limiting dilution cloning. To produce a clonal P. berghei blood stage infection from a non-clonal infection using this procedure requires between 4 and 5 weeks.

  16. Giant Retinal Tear With Retinal Detachment in Regressed Aggressive Posterior Retinopathy of Prematurity Treated by Laser.

    Science.gov (United States)

    Chandra, Parijat; Tewari, Ruchir; Salunkhe, Nitesh; Kumawat, Devesh; Kumar, Vinod

    2017-06-29

    Rhegmatogenous retinal detachment after successfully regressed retinopathy of prematurity is a rare occurrence. Late onset rhegmatogenous retinal detachment has been reported infrequently. The authors report a case of aggressive posterior retinopathy of prematurity that underwent uneventful regression after laser photocoagulation and later developed an inoperable closed funnel retinal detachment due to a giant retinal tear. This case represents the earliest development of such complications in regressed aggressive posterior retinopathy of prematurity treated by laser. Development of a giant retinal tear has also not been previously reported after laser treatment. This case highlights that successful regression of severe retinopathy of prematurity does not safeguard against future complications and requires frequent long-term follow-up. [J Pediatr Ophthalmol Strabismus. 2017;54:e34-e36.]. Copyright 2017, SLACK Incorporated.

  17. Static and dynamic behaviors of plasma detachment in divertor simulator NAGDIS-II

    International Nuclear Information System (INIS)

    Takamura, S.; Ohno, N.; Uesugi, Y.; Nishijima, D.; Motoyama, M.; Hattori, N.; Arakawa, H.; Krasheninnikov, S.I.; Pigarov, A.; Wenzel, U.

    2001-01-01

    We have performed comprehensive investigation on the static and dynamic behaviors in detached recombining plasmas in the linear divertor plasma simulator, NAGDIS-II. For the stationary plasma detachment, the transition from electron-ion recombination (EIR) to molecular activated recombination (MAR) has been observed by injecting hydrogen gas to high density He plasmas. The particle loss rate due to MAR is found to be comparable to that of EIR. We have also performed experiments on injection of a plasma heat pulse produced by rf heating to the detached recombining He plasma to demonstrate the dynamic behavior of the volumetric plasma recombination. Negative spikes in Balmer series line emissions were observed similar to the so called negative ELM observed in tokamak divertors, which were analyzed with collisional-radiative model in detail. Rapid increase of the ion flux to the target plate was observed associated with the re-ionization of the highly excited atoms generated by EIR. (author)

  18. Photo excitation and laser detachment of C60 − anions in a storage ring

    DEFF Research Database (Denmark)

    Støchkel, Kristian; Andersen, Jens Ulrik

    2013-01-01

    We have studied the photo physics of C60 − anions in the electrostatic storage ring ELISA with ions produced in a plasma source and cooled and bunched in a He filled ion trap. A previous study using delayed electron detachment as a signal of resonance-enhanced multiphoton electron detachment...... from a principal component analysis of these spectra. In good agreement with the earlier REMPED experiment, an origin band for transitions between the two lowest electronic levels of the anion, with t 1u and t 1g symmetry, is observed at 9380 cm−1, with strong sidebands from excitation of the two A g...... level, is much weaker in the new measurements and could be an H g vibrational sideband. Also earlier studies of direct laser detachment from C60 − in the storage ring ASTRID have been revisited, with ions cooled by liquid nitrogen in the ion trap. We confirm the previous measurement with a determination...

  19. Photorefractive keratectomy for visual rehabilitation of anisometropia induced by retinal detachment surgery.

    Science.gov (United States)

    Bilgihan, K; Ozdek, S C; Gürelik, G; Adigüzel, U; Onol, M; Hasanreisoglu, B

    2000-01-01

    To evaluate the efficacy of unilateral photorefractive keratectomy to correct anisometropia induced by retinal detachment surgery. Photorefractive keratectomy was performed in 10 eyes of 10 patients with anisometropia induced by previous retinal detachment surgery. The Aesculap Meditec MEL 60 excimer laser was used. Preoperative mean spherical equivalent refraction was -5.20 D. Mean postoperative spherical equivalent refraction was -0.25 D after a mean follow-up of 12.9 months. Mean preoperative spherical equivalent refraction difference between two eyes of 4.87 D was decreased to a mean 0.60 D postoperatively (t-test, P < .0001). All patients were free of anisometropic symptoms after laser surgery. Unilateral photorefractive keratectomy seems to be an effective method to correct anisometropia induced by conventional retinal detachment surgery, especially for patients with spectacle and contact lens intolerance.

  20. Microperimetry and optical coherent tomography in patients operated on y the conventional retinal detachment surgery

    International Nuclear Information System (INIS)

    Guerra Garcia, Roberto Alejandro; Rodriguez Rodriguez, Beatriz N; Eguia Martinez, Frank

    2008-01-01

    A descriptive study was made to determine the visual acuity, microperimetry and optical coherence tomography in patients operated on by the conventional rhegmatogenous retinal detachment at 'Ramon Pando Ferrer' Cuban Ophthalmologic Institute from October 2006 to March 2007. Twenty six patients, who had gone to the hospital with normal values in ophthalmoscopy and biomicroscopy and three-six months of disease development. Better corrected visual acuity, fixation, average sensitivity, morphology and macular thickness were obtained after surgery. Average visual acuity was 0,41 and fixation was stable in most of patients; average retinal sensitivity was 11 decibels. The most frequent finding was serum detachment. Average macular thickness was 246,3 micras. There was no statistical relation between preoperative time of disease development and the macular characteristics of detachment in these tests. (Author)

  1. [Serous macular detachment associated with circumscribed choroidal hemangioma: a case report].

    Science.gov (United States)

    Munteanu, M; Giuri, Stela; Rosca, C; Boruga, O; Chercota, V; Stanca, H T

    2013-01-01

    Choroidal hemangiomas are benign vascular hamartomas that typically present from second to fourth decade of life, when they can cause visual disturbance due to exudative retinal detachment. They represent uncommon benign choroidal vascular tumors, usually occuring sporadically in the absence of systemic disease. We report the case of a young female patient, presenting a juxtapapillary circumscribed choroidal haemangioma complicated with serous macular detachment. The patient underwent photodynamic therapy with verteporfin (PDT). Systematic follow-up using ophthalmoscopy, ultrasonography, Fluorescein angiography and Indocyanine green angiography was performed. The patient presented regression with flattening of tumour, resolution of the subretinal fluid, and significant improvement of vision. Mostly asymptomatic, the choroidal hemangiomas can be associated with serous retinal detachment, leading to reduced vision and metamorphopsia; in those cases, the long term visual prognosis is poor, even in adequately treated patients. PDT is effective in eliminating the subretinal fluid and improving vision in patients with circumscribed choroidal hemangioma.

  2. Return to work and risk of subsequent detachment from employment after myocardial infarction

    DEFF Research Database (Denmark)

    Smedegaard, Laerke; Numé, Anna Karin; Charlot, Mette

    2017-01-01

    Background--Limited data are available on return to work and subsequent detachment from employment after admission for myocardial infarction (MI). Methods and Results--Using individual-level linkage of data from nationwide registries, we identified patients of working age (30-65 years) discharged...... after first-time MI in the period 1997 to 2012, who were employed before admission. To assess the cumulative incidence of return to work and detachment from employment, the Aalen Johansen estimator was used. Incidences were compared with population controls matched on age and sex. Logistic regression...... was applied to estimate odds ratios for associations between detachment from employment and age, sex, comorbidities, income, and education level. Of 39 296 patients of working age discharged after first-time MI, 22 394 (56.9%) were employed before admission. Within 1 year 91.1% (95% confidence interval [CI...

  3. Visual and anatomical outcomes of macular epiretinal membrane peeling after previous rhegmatogenous retinal detachment repair.

    Science.gov (United States)

    Weng, Christina Y; Gregori, Ninel Z; Moysidis, Stavros N; Shi, Wei; Smiddy, William E; Flynn, Harry W

    2015-01-01

    To report outcomes and prognostic factors after epiretinal membrane peeling in patients with previous rhegmatogenous retinal detachment repair. A consecutive case series. Best-corrected visual acuity and optical coherence tomography characteristics were analyzed before and after epiretinal membrane surgery. Fifty-three eyes were analyzed. Best-corrected visual acuity improved by a mean of 10 letters at 1 month (N = 45; P = 0.001), 15 at 3 months (N = 42; P detachment repair resulted in significant improvements in visual acuity and optical coherence tomography thickness, even in eyes with previous macula-involving rhegmatogenous retinal detachment. Better preoperative visual acuity and intact outer retinal layers by optical coherence tomography were the main prognostic factors for visual outcomes.

  4. A SECOND CASE OF BILATERAL RHEGMATOGENOUS RETINAL DETACHMENTS REPAIRED WITH SIMULTANEOUS BILATERAL PNEUMATIC RETINOPEXY.

    Science.gov (United States)

    Rubin, Uriel; De Jager, Cornelis; Zakour, Moayed; Gonder, J Thomas

    2017-01-01

    To present a case of a patient with simultaneous bilateral retinal detachments treated successfully with bilateral pneumatic retinopexy. Case report. This is a case of an otherwise healthy 49-year-old woman with no remarkable ocular history that presented with simultaneous phakic superior bilateral rhegmatogenous retinal detachments. Treatment on the day of presentation included laser retinopexy of the inferior lattice degeneration in the left eye and bilateral intravitreal injection of 0.4 cc of 100% C3F8 gas preceded by topical anesthesia. After 48 hours, both retinas were completely reattached, and bilateral laser retinopexy was performed to the superior tears. After a review of the literature, the authors could find only two reported cases of simultaneous bilateral retinal detachments treated successfully with pneumatic retinopexy. This is not only a cost-effective procedure but also allows treatment when there is no immediate operating room availability or a when a quick referral for surgery is not possible.

  5. Measurement of He neutral temperature in detached plasmas using laser absorption spectroscopy

    Science.gov (United States)

    Aramaki, M.; Tsujihara, T.; Kajita, S.; Tanaka, H.; Ohno, N.

    2018-01-01

    The reduction of the heat load onto plasma-facing components by plasma detachment is an inevitable scheme in future nuclear fusion reactors. Since the control of the plasma and neutral temperatures is a key issue to the detached plasma generation, we have developed a laser absorption spectroscopy system for the metastable helium temperature measurements and used together with a previously developed laser Thomson scattering system for the electron temperature and density measurements. The thermal relaxation process between the neutral and the electron in the detached plasma generated in the linear plasma device, NAGDIS-II was studied. It is shown that the electron temperature gets close to the neutral temperature by increasing the electron density. On the other hand, the pressure dependence of electron and neutral temperatures shows the cooling effect by the neutrals. The possibility of the plasma fluctuation measurement using the fluctuation in the absorption signal is also shown.

  6. On the electric breakdown field of the mesosphere and the influence of electron detachment

    DEFF Research Database (Denmark)

    Neubert, Torsten; Chanrion, Olivier Arnaud

    2013-01-01

    that the threshold field decreases with time and can reach values well below the conventional threshold field. The concept of a fixed threshold field therefore itself breaks down. We find that the growth rate decreases with decreasing electric field and that long exposure time of electric fields therefore is needed......It has been suggested recently that electron associative detachment from negative atomic oxygen ions provides an additional source of free electrons in electric discharges of the mesosphere, the sprites, and gigantic jets. Here we study attachment under some simplifying assumptions and show...... for electron avalanches to grow. Detachment is likely to affect the conductivity of streamer filaments and other long-lasting space charge structures like gigantic jets or the ionization state of the mesosphere when illuminated by thunderstorm fields. Detachment by itself does not directly affect small...

  7. A case of Alagille syndrome complicated by intraocular lens subluxation and rhegmatogenous retinal detachment

    Science.gov (United States)

    Fukumoto, Masanori; Ikeda, Tsunehiko; Sugiyama, Tetsuya; Ueki, Mari; Sato, Takaki; Ishizaki, Eisuke

    2013-01-01

    This case report describes a case of Alagille syndrome with developing intraocular lens subluxation and rhegmatogenous retinal detachment 4 years after cataract surgery. A 15-year-old female patient with Alagille syndrome-associated cataracts in both eyes underwent phacoemulsification aspiration and intraocular lens implantation. Four years postoperative, intraocular lens subluxation developed in her left eye. For treatment, extraction of the dislocated intraocular lens, anterior vitrectomy, and intraocular lens fixation was performed. Three weeks later, the patient developed rhegmatogenous retinal detachment, which was well-treated by pars plana vitrectomy. Cataract surgery needs to be performed carefully in patients with Alagille syndrome due to the weakness of the zonule of Zinn. Careful postoperative observation is necessary for patients with Alagille syndrome who have undergone intraocular surgery in order to facilitate early detection of a possible rhegmatogenous retinal detachment. PMID:23898221

  8. Dietary Salt Exacerbates Experimental Colitis.

    Science.gov (United States)

    Tubbs, Alan L; Liu, Bo; Rogers, Troy D; Sartor, R Balfour; Miao, Edward A

    2017-08-01

    The Western diet is characterized by high protein, sugar, fat, and low fiber intake, and is widely believed to contribute to the incidence and pathogenesis of inflammatory bowel disease (IBD). However, high sodium chloride salt content, a defining feature of processed foods, has not been considered as a possible environmental factor that might drive IBD. We set out to bridge this gap. We examined murine models of colitis on either a high salt diet (HSD) or a low salt diet. We demonstrate that an HSD exacerbates inflammatory pathology in the IL-10-deficient murine model of colitis relative to mice fed a low salt diet. This was correlated with enhanced expression of numerous proinflammatory cytokines. Surprisingly, sodium accumulated in the colons of mice on an HSD, suggesting a direct effect of salt within the colon. Similar to the IL-10-deficient model, an HSD also enhanced cytokine expression during infection by Salmonella typhimurium This occurred in the first 3 d of infection, suggesting that an HSD potentiates an innate immune response. Indeed, in cultured dendritic cells we found that high salt media potentiates cytokine expression downstream of TLR4 activation via p38 MAPK and SGK1. A third common colitis model, administration of dextran sodium sulfate, was hopelessly confounded by the high sodium content of the dextran sodium sulfate. Our results raise the possibility that high dietary salt is an environmental factor that drives increased inflammation in IBD. Copyright © 2017 by The American Association of Immunologists, Inc.

  9. Dynamics of thin-skinned fold and thrust belts with a tilted detachment

    Science.gov (United States)

    Fernandez, Naiara; Kaus, Boris J. P.; Epard, Jean-Luc

    2014-05-01

    The formation of the Jura fold and thrust belt is linked to the Alpine orogeny. However, it is still a matter of debate why the Jura was formed tens of kilometres far away from the active deformation front while the Molasse basin that lies in between remained mostly undeformed. Progressive thickening of the Molasse basin due to its infill with sediments, and the existence of a tilted potential detachment level at the Triassic evaporitic units, have been pushed forward as the main causes for the detachment of the Molasse basin and the consequent jump of the deformation front from the Alpine front to the position of the Jura at around 22 Ma or later (e.g Willett and Schlunegger, 2010). In order to better understand the dynamics of a thin-skinned fold and thrust belt with a tilted detachment we have performed systematic forward numerical simulations with the 2D thermo-mechanical finite element code MILAMIN_VEP. The modelled setup consists of a tilted detachment, overlain by a sedimentary cover of constant thickness and a wedge shaped basin infill that makes the initial surface slope of the system to be zero. In this study we have tested the importance of the following factors in the dynamics of such a fold and thrust belt evolution: 1) the applied boundary conditions 2) the angle of a uniformly tilted detachment 3) the end displacement of a curved detachment with a flexural foreland basin profile. The implications of the studied factors are discussed for the case of the Jura-Molasse system. Acknowledgements Funding was provided by the European Research Council under the European Community's Seventh Framework program (FP7/2007-2013) ERC Grant agreement #258830. References Willett, S.D. and Schlunegger, F. 2010, The last phase of deposition in the Swiss Molasse Basin: from foredeep to negative-alpha basin. Basin Research 22, 623-639, doi: 10.1111/j.1365-2117.2009.00435.x

  10. Septal Leaflet versus Chordal Detachment in Closure of Hard-To-Expose Ventricular Septal Defects.

    Science.gov (United States)

    Pourmoghadam, Kamal K; Boron, Agnieszka; Ruzmetov, Mark; Narasimhulu, Sukumar Suguna; Kube, Alicia; O'Brien, Michael C; DeCampli, William M

    2018-04-04

    Different techniques have been used for exposure of ventricular septal defect (VSD) margins when there is crowding of the VSD anatomy by tricuspid valve (TV) subvalvar apparatus. The aim of this study was to compare surgical outcomes, for the two techniques of TV leaflet detachment and the rarely described TV chordal detachment for hard-to-expose VSDs. Patients undergoing transatrial VSD repair were identified from our institutional database. Follow-up echocardiography and patient data were obtained from medical records. Between 1/2005-8/2016, 130 isolated conoventricular VSDs were repaired. Among these, 26patients had leaflet detachment, while 15 underwent chordal detachment, and 89 had regular VSD repair (reference group). There was no significant difference between the groups in age, weight, postoperative length-of-stay, genetic/syndromic abnormalities, time-to-extubation, and left and right ventricular systolic function. The cardiopulmonary bypass and cross-clamp time were significantly higher in leaflet detachment group, when compared with reference group (118+28vs102+32, p=0.02; and 73+20vs61+23, p=0.01, respectively). Echocardiographic follow-up were available for 87patients at a mean of 2.6years (1month-11years). Tricuspid regurgitation was rated as none or trivial in 66(76%), mild in 20(23%) and moderate in one reference group patient. There was no difference in presence of residual VSD, or degree of tricuspid regurgitation amongst the three groups. There was no reoperation for tricuspid regurgitation. Tricuspid valve leaflet and chordal detachment techniques provide equally viable and safe alternative to closure of hard-to-expose VSDs while maintaining appropriate TV function. Their use in our series did not lead to increased TV dysfunction at early-to-midterm echocardiographic assessment. Copyright © 2018. Published by Elsevier Inc.

  11. FTIR measurements of OH in deformed quartz and feldspars of the South Tibetan Detachment, Greater Himalaya

    Science.gov (United States)

    Jezek, L.; Law, R. D.; Jessup, M. J.; Searle, M. P.; Kronenberg, A. K.

    2017-12-01

    OH absorption bands due to water in deformed quartz and feldspar grains of mylonites from the low-angle Lhotse Detachment (of the South Tibetan Detachment System, Rongbuk Valley north of Mount Everest) have been measured by Fourier Transform Infrared (FTIR) Spectroscopy. Previous microstructural studies have shown that these rocks deformed by dislocation creep at high temperature conditions in the middle crust (lower - middle amphibolite facies), and oxygen isotope studies suggest significant influx of meteoric water. OH absorption bands at 3400 cm-1 of quartz mylonites from the footwall of the Lhotse Detachment Fault are large, with the character of the molecular water band due to fluid inclusions in milky quartz. Mean water contents depend on structural position relative to the core of the Lhotse Detachment, from 1000 ppm (OH/106 Si) at 420 m below the fault to 11,350 (+/-1095) ppm near its center. The gradient in OH content shown by quartz grains implies influx of meteoric water along the Lhotse Detachment from the Tibetan Plateau ground surface to middle crustal depths, and significant fluid penetration into the extruding Himalayan slab by intergranular, permeable fluid flow processes. Feldspars of individual samples have comparable water contents to those of quartz and some are wetter. Large water contents of quartz and feldspar may have contributed to continued deformation and strain localization on the South Tibetan Detachment System. Dislocation creep in quartz is facilitated by water in laboratory experiments, and the water contents of the Lhotse fault rocks are similar to (and even larger than) water contents of quartz experimentally deformed during water weakening. Water contents of feldspars are comparable to those of plagioclase aggregates deformed experimentally by dislocation and diffusion creep under wet conditions.

  12. VISUAL AND ANATOMICAL OUTCOMES AFTER DIABETIC TRACTION AND TRACTION-RHEGMATOGENOUS RETINAL DETACHMENT REPAIR.

    Science.gov (United States)

    Storey, Philip P; Ter-Zakarian, Anna; Philander, Shannon A; Olmos de Koo, Lisa; George, Meena; Humayun, Mark S; Rodger, Damien C; Ameri, Hossein

    2017-08-08

    To evaluate visual and anatomical outcomes of diabetic tractional retinal detachment repaired with pars plana vitrectomy. Operative records were used to retrospectively identify all patients with tractional retinal detachments secondary to proliferative diabetic retinopathy surgically repaired with pars plana vitrectomy between November 1, 2009, and January 1, 2015 at the LAC + USC (Los Angeles County + University of Southern California) Medical Center. A total of 403 eyes with diabetic tractional retinal detachment in 359 patients were included. Successful reattachment of the retina was achieved in 87.6% of eyes after one surgery and 92.6% of eyes at the final follow-up. Best-corrected visual acuity at the final follow-up improved two or more lines in 56.3% of eyes, was stable in 23.8% of eyes, and decreased two or more lines in 19.9% of eyes. Eyes repaired with 23-gauge and 25-gauge vitrectomy systems had similar success rates as eyes treated with 20-gauge instrumentation (P = 0.73). Eyes receiving silicone oil tamponade had lower single-surgery reattachment rates (77.6% vs. 87.6%; P = 0.013), lower reattachment rates at the final follow-up (85.7% vs. 92.6%; P = 0.048), and higher rates of vision loss (34.7% vs. 19.9%; P detachment (47.0% vs. 21.3%; P detachment (74.5% vs. 60.0%; P detachment, vitrectomy achieved excellent anatomical outcome and improved or stabilized vision in 80.1% of eyes. Smaller gauge vitrectomy systems were found to have similar outcomes to 20-gauge instrumentation.

  13. Traction on the retina induced by saccadic eye movements in the presence of posterior vitreous detachment.

    Science.gov (United States)

    Repetto, R; Tatone, A; Testa, A; Colangeli, E

    2011-04-01

    Posterior vitreous detachment is a fairly common condition in elderly people. Tractions exerted by the detached vitreous on the retina may result in retinal tears and detachments. We studied how these tractions can arise from saccadic eye movements. Numerical simulations have been performed on a two-dimensional model of the vitreous chamber within a rigid spherical sclera, subjected to prescribed finite-amplitude rotations about a vertical axis. The vitreous chamber was assumed to be split into two regions: one occupied by the detached vitreous, modeled as an elastic viscous solid, and the other occupied by the separated liquefied vitreous, modeled as a Newtonian fluid. At the interface between the two phases, we also considered the presence of the vitreous cortex, modeled as an elastic membrane. We tested several different configurations of the interface. In all cases, we found that eye rotations generate large tractions on the retina close to the attachment points of the membrane. Comparing them, we identified configurations of the vitreous detachment that exhibit higher tractions. We also investigated how the response to saccadic movements depends on some physical parameters, in particular on the rheological properties of the solid phase and the membrane. The numerical simulations show that the generated tractions may be of the same order of magnitude as the adhesive force between the retina and the pigment epithelium. Therefore, the model provides a sound physical justification for the hypothesis that saccadic movements, in the presence of posterior vitreous detachment, could be responsible for high tractions on the retina, which may trigger retinal tear formation.

  14. Emotional detachment in psychopathy: Involvement of dorsal default-mode connections.

    Science.gov (United States)

    Sethi, Arjun; Gregory, Sarah; Dell'Acqua, Flavio; Periche Thomas, Eva; Simmons, Andy; Murphy, Declan G M; Hodgins, Sheilagh; Blackwood, Nigel J; Craig, Michael C

    2015-01-01

    Criminal psychopathy is defined by emotional detachment [Psychopathy Checklist - Revised (PCL-R) factor 1], and antisocial behaviour (PCL-R factor 2). Previous work has associated antisocial behaviour in psychopathy with abnormalities in a ventral temporo-amygdala-orbitofrontal network. However, little is known of the neural correlates of emotional detachment. Imaging studies have indicated that the 'default-mode network' (DMN), and in particular its dorsomedial (medial prefrontal - posterior cingulate) component, contributes to affective and social processing in healthy individuals. Furthermore, recent work suggests that this network may be implicated in psychopathy. However, no research has examined the relationship between psychopathy, emotional detachment, and the white matter underpinning the DMN. We therefore used diffusion tensor imaging (DTI) tractography in 13 offenders with psychopathy and 13 non-offenders to investigate the relationship between emotional detachment and the microstructure of white matter connections within the DMN. These included the dorsal cingulum (containing the medial prefrontal - posterior cingulate connections of the DMN), and the ventral cingulum (containing the posterior cingulate - medial temporal connections of the DMN). We found that fractional anisotropy (FA) was reduced in the left dorsal cingulum in the psychopathy group (p = .024). Moreover, within this group, emotional detachment was negatively correlated with FA in this tract portion bilaterally (left: r = -.61, p = .026; right: r = -.62, p = .023). These results suggest the importance of the dorsal DMN in the emotional detachment observed in individuals with psychopathy. We propose a 'dual-network' model of white matter abnormalities in the disorder, which incorporates these with previous findings. Copyright © 2014 Elsevier Ltd. All rights reserved.

  15. Does colloid shape affect detachment of colloids by a moving air-water interface?

    Science.gov (United States)

    Aramrak, Surachet; Flury, Markus; Harsh, James B; Zollars, Richard L; Davis, Howard P

    2013-05-14

    Air-water interfaces interact strongly with colloidal particles by capillary forces. The magnitude of the interaction force depends on, among other things, the particle shape. Here, we investigate the effects of particle shape on colloid detachment by a moving air-water interface. We used hydrophilic polystyrene colloids with four different shapes (spheres, barrels, rods, and oblong disks), but otherwise identical surface properties. The nonspherical shapes were created by stretching spherical microspheres on a film of polyvinyl alcohol (PVA). The colloids were then deposited onto the inner surface of a glass channel. An air bubble was introduced into the channel and passed through, thereby generating a receding followed by an advancing air-water interface. The detachment of colloids by the air-water interfaces was visualized with a confocal microscope, quantified by image analysis, and analyzed statistically to determine significant differences. For all colloid shapes, the advancing air-water interface caused pronounced colloid detachment (>63%), whereas the receding interface was ineffective in colloid detachment (colloid shapes, the barrels were most readily removed (94%) by the advancing interface, followed by the spheres and oblong disks (80%) and the rods (63%). Colloid detachment was significantly affected by colloid shape. The presence of an edge, as it occurs in a barrel-shaped colloid, promoted colloid detachment because the air-water interface is being pinned at the edge of the colloid. This suggests that the magnitude of colloid mobilization and transport in porous media is underestimated for edged particles and overestimated for rodlike particles when a sphere is used as a model colloid.

  16. Transcriptomic analysis of human retinal detachment reveals both inflammatory response and photoreceptor death.

    Directory of Open Access Journals (Sweden)

    Marie-Noëlle Delyfer

    Full Text Available BACKGROUND: Retinal detachment often leads to a severe and permanent loss of vision and its therapeutic management remains to this day exclusively surgical. We have used surgical specimens to perform a differential analysis of the transcriptome of human retinal tissues following detachment in order to identify new potential pharmacological targets that could be used in combination with surgery to further improve final outcome. METHODOLOGY/PRINCIPAL FINDINGS: Statistical analysis reveals major involvement of the immune response in the disease. Interestingly, using a novel approach relying on coordinated expression, the interindividual variation was monitored to unravel a second crucial aspect of the pathological process: the death of photoreceptor cells. Within the genes identified, the expression of the major histocompatibility complex I gene HLA-C enables diagnosis of the disease, while PKD2L1 and SLCO4A1 -which are both down-regulated- act synergistically to provide an estimate of the duration of the retinal detachment process. Our analysis thus reveals the two complementary cellular and molecular aspects linked to retinal detachment: an immune response and the degeneration of photoreceptor cells. We also reveal that the human specimens have a higher clinical value as compared to artificial models that point to IL6 and oxidative stress, not implicated in the surgical specimens studied here. CONCLUSIONS/SIGNIFICANCE: This systematic analysis confirmed the occurrence of both neurodegeneration and inflammation during retinal detachment, and further identifies precisely the modification of expression of the different genes implicated in these two phenomena. Our data henceforth give a new insight into the disease process and provide a rationale for therapeutic strategies aimed at limiting inflammation and photoreceptor damage associated with retinal detachment and, in turn, improving visual prognosis after retinal surgery.

  17. Influence of yellow rust infection on /sup 32/P transport in detached barley leaves

    Energy Technology Data Exchange (ETDEWEB)

    Schubert, J. (Akademie der Landwirtschaftswissenschaften der DDR, Aschersleben. Inst. fuer Phytopathologie)

    1982-01-01

    Several barley cultivars (Hordeum vulgare L.) differing in their resistance to yellow rust (Puccinia striiformis West.) were tested for relationships between changes of /sup 32/P transport in detached leaves and resistance to yellow rust disease. Investigation carried out with detached second leaves from plants infected at their first leaf revealed a matter transport in these leaves changed by the infection. Transport was also influenced by inoculation with yellow rust uredospores. In that case rust infection influenced the basipetal transport less strongly in resistent plants than in susceptible ones. Connected with the findings the influence of fungal substances on transport processes is discussed in general.

  18. Analysis of throw distances of detached objects from horizontal-axis wind turbines

    DEFF Research Database (Denmark)

    Chivaee, Hamid Sarlak; Sørensen, Jens Nørkær

    2016-01-01

    This paper aims at predicting trajectories of the detached fragments from wind turbines, in order to better quantify consequences of wind turbine failures. The trajectories of thrown objects are attained using the solution to equations of motion and rotation, with the external loads and moments...... are simulated for modern wind turbines ranging in size from 2 to 20 MW using upscaling laws. Extensive parametric analyses are performed against initial release angle, tip speed ratio, detachment geometry, and blade pitch setting. It is found that, while at tip speeds of about 70 m/s (normal operating...

  19. Retinal pigment epithelial atrophy following indocyanine green dye-assisted surgery for serous macular detachment

    Directory of Open Access Journals (Sweden)

    Hussain Nazimul

    2008-01-01

    Full Text Available To report subretinal migration of indocyanine green dye (ICG and subsequent retinal pigment epithelial (RPE atrophy during macular surgery for serous macular detachment. A 65-year-old woman presented with residual epiretinal membrane and serous detachment of the macula following vitreoretinal surgery for epiretinal membrane. She underwent resurgery with ICG-assisted internal limiting membrane peeling and intraocular tamponade. Intraoperatively a large area of subretinal ICG was seen with subsequent RPE mottling and atrophy of the macula in the area involved during follow-up. This case demonstrates that subretinal migration of ICG is possible and can be toxic to RPE.

  20. The effect of attachment and detachment on totally asymmetric exclusion processes with junctions

    International Nuclear Information System (INIS)

    Cai Zhongpan; Yuan Yaoming; Jiang Rui; Wu Qingsong; Nishinari, Katsuhiro

    2009-01-01

    In this paper, we investigate totally asymmetric exclusion processes on lattices with junctions, considering random particle attachment and detachment in the bulk. Particles randomly attach to the bulk with the rate ω A and detach from the bulk with the rate ω D . Setting K = ω A /ω D , we study three cases: K>1, K = 1 and K 1, additional phases are observed in the case of K≤1. Moreover, it is shown that at a fixed K, the phase diagram structure changes with the increase of ω D . A mean-field analysis has been carried out and the analytic results are in good agreement with the simulation results

  1. Intravitreal bevacizumab therapy for idiophatic juxtafoveolar retinal telangiectasis associated with serous macular detachment

    Directory of Open Access Journals (Sweden)

    Paulo Escarião

    2014-01-01

    Full Text Available The authors describe a 50-year-old woman with group 2 juxtafoveolar retinal telangiectasis and macular detachment treated with a single-dose of intravitreous bevacizumab injection. There was an improvement in her visual acuity, with a decrease in retinal thickness showed by the optical coherence tomography and fluorescein leakage in the angiography on follow-up visits. No adverse events were observed as a result of the treatment used. After one year of follow-up, the vision remained stable and macular detachment did not recur.

  2. Surgical management of retinal diseases: proliferative diabetic retinopathy and traction retinal detachment.

    Science.gov (United States)

    Cruz-Iñigo, Yousef J; Acabá, Luis A; Berrocal, Maria H

    2014-01-01

    Current indications for pars plana vitrectomy in patients with proliferative diabetic retinopathy (PDR) include vitreous hemorrhage, tractional retinal detachment (TRD), combined tractional and rhegmatogenous retinal detachment (CTRRD), diabetic macular edema associated with posterior hyaloidal traction, and anterior segment neovascularization with media opacities. This chapter will review the indications, surgical objectives, adjunctive pharmacotherapy, microincision surgical techniques, and outcomes of diabetic vitrectomy for PDR, TRD, and CTRRD. With the availability of new microincision vitrectomy technology, wide-angle microscope viewing systems, and pharmacologic agents, vitrectomy can improve visual acuity and achieve long-term anatomic stability in eyes with severe complications from PDR. © 2014 S. Karger AG, Basel

  3. Influence of yellow rust infextion on 32P transport in detached barley leaves

    International Nuclear Information System (INIS)

    Schubert, J.

    1982-01-01

    Several barley cultivars (Hordeum vulgare L.) differing in their resistance to yellow rust (Puccinia striiformis West.) were tested for relationships between changes of 32 P transport in detached leaves and resistance to yellow rust disease. Investigation carried out with detached second leaves from plants infected at their first leaf revealed a matter transport in these leaves changed by the infection. Transport was also influenced by inoculation with yellow rust uredospores. In that case rust infection influenced the basipetal transport less strongly in resistent plants than in susceptible ones. Connected with the findings the influence of fungal substances on transport processes is discussed in general. (author)

  4. Free and proteic aminoacids from acetate 14C metabolism in detached leaves of coffee plant

    International Nuclear Information System (INIS)

    Brasil, O.G.; Crocomo, O.J.

    1981-01-01

    The acetate 14 C was studied as the forerunner of proteic and free aminoacids in detached leaves of coffee (coffea arabica L.cv. Mundo Novo). The detached leaves were incubated with acetate -1- 14 C and -2- 14 C during several times (15, 30, 45, 60, 90, 120, 150 and 180 minutes), out of luminosity. The ethanol 80% soluble fraction gave origin to free aminoacid after ion - exchange chromatography. The insoluble fraction through acid hydrolisis furnished proteic aminoacids. The data showed that the acetate molecules contributed for the aminoacids molecules structure, methylic carbon being more incorporated than the carboxylic carbon. (Author) [pt

  5. Young Stars with SALT

    Science.gov (United States)

    Riedel, Adric R.; Alam, Munazza K.; Rice, Emily L.; Cruz, Kelle L.; Henry, Todd J.

    2017-05-01

    We present a spectroscopic and kinematic analysis of 79 nearby M dwarfs in 77 systems. All of these dwarfs are low-proper-motion southern hemisphere objects and were identified in a nearby star survey with a demonstrated sensitivity to young stars. Using low-resolution optical spectroscopy from the Red Side Spectrograph on the South African Large Telescope, we have determined radial velocities, H-alpha, lithium 6708 Å, and potassium 7699 Å equivalent widths linked to age and activity, and spectral types for all of our targets. Combined with astrometric information from literature sources, we identify 44 young stars. Eighteen are previously known members of moving groups within 100 pc of the Sun. Twelve are new members, including one member of the TW Hydra moving group, one member of the 32 Orionis moving group, 9 members of Tucana-Horologium, one member of Argus, and two new members of AB Doradus. We also find 14 young star systems that are not members of any known groups. The remaining 33 star systems do not appear to be young. This appears to be evidence of a new population of nearby young stars not related to the known nearby young moving groups. Based on observations made with the Southern African Large Telescope (SALT).

  6. Sodium (Salt or Sodium Chloride)

    Science.gov (United States)

    ... pick up the salt shaker. Get tips on cutting back and how to build a healthier relationship ... from the start. Healthy Eating • Healthy Eating Home • Nutrition AHA Diet and Lifestyle Recommendations Making Healthy Choices ...

  7. Lowering Salt in Your Diet

    Science.gov (United States)

    ... and salt that cooks add to foods at restaurants and other food service establishments. Q. What are ... State & Local Officials Consumers Health Professionals Science & Research Industry Scroll back to top Popular Content Home Latest ...

  8. Microbiology of solar salt ponds

    Science.gov (United States)

    Javor, B.

    1985-01-01

    Solar salt ponds are shallow ponds of brines that range in salinity from that of normal seawater (3.4 percent) through NaCl saturation. Some salterns evaporate brines to the potash stage of concentration (bitterns). All the brines (except the bitterns, which are devoid of life) harbor high concentrations of microorganisms. The high concentrations of microorganisms and their adaptation to life in the salt pond are discussed.

  9. RhoA Inactivation Prevents Photoreceptor Axon Retraction in an In Vitro Model of Acute Retinal Detachment

    OpenAIRE

    Fontainhas, Aurora Maria; Townes-Anderson, Ellen

    2011-01-01

    Axon retraction by rod cells is an early response to detachment that likely contributes to poor outcomes after reattachment. In mammalian retina, blocking RhoA signaling prevents axon retraction. Effective treatment can occur as much as 6 hours after the detachment.

  10. Incidence, risk factors, and clinical characteristics of unexplained visual loss after intraocular silicone oil for macula-on retinal detachment

    NARCIS (Netherlands)

    Scheerlinck, Laura M.; Schellekens, Peter A.; Liem, Albert T.; Steijns, Daan; van Leeuwen, R

    2016-01-01

    Purpose: To investigate the incidence, risk factors, and clinical characteristics of unexplained visual loss after macula-on rhegmatogenous retinal detachment (RRD). Methods: Retrospective cohort of patients with primary macula-on rhegmatogenous retinal detachment treated by vitrectomy with gas or

  11. Overexpression of the X-Linked Inhibitor of Apoptosis Protects Against Retinal Degeneration in a Feline Model of Retinal Detachment.

    Science.gov (United States)

    Wassmer, Sarah J; Leonard, Brian C; Coupland, Stuart G; Baker, Adam N; Hamilton, John; Hauswirth, William W; Tsilfidis, Catherine

    2017-06-01

    Retinal detachment is an acute disorder in humans that is caused by trauma or disease, and it can often lead to permanent visual deficits that result from the death of photoreceptors in the retina. The final pathway for photoreceptor cell death is apoptosis and necroptosis. The X-linked inhibitor of apoptosis (XIAP) has been shown to block both of these cell death pathways. This study tested the effects of XIAP on photoreceptor survival in a feline model of retinal detachment. The study was performed in 12 cats, divided into two experimental groups. Six animals received a subretinal injection of adeno-associated virus (AAV) carrying XIAP, and six animals received AAV carrying green fluorescent protein (GFP) as a control. Three weeks after viral delivery, retinas were detached by injecting C 3 F 8 gas into the subretinal space. Optical coherence tomography revealed that the retinal detachments resolved within 3-6 weeks as the gas was slowly resorbed. Analysis of histological sections through the plane of the detachment showed significant preservation of the photoreceptor layer in AAV-XIAP-treated animals compared to AAV-GFP-treated animals at 9 weeks after the detachment. XIAP-treated detached retinas were similar to intact controls. These studies support the potential for XIAP therapy in the treatment of human retinal detachment.

  12. Air bubble-induced detachment of polystyrene particles with different sizes from collector surfaces in a parallel plate flow chamber

    NARCIS (Netherlands)

    Gomez-Suarez, C; van der Mei, HC; Busscher, HJ

    2001-01-01

    Particle size was found to be an important factor in air bubble-induced detachment of colloidal particles from collector surfaces in a parallel plate flow chamber and generally polystyrene particles with a diameter of 806 nm detached less than particles with a diameter of 1400 nm. Particle

  13. Hydrogen-bonding catalysis of sulfonium salts

    OpenAIRE

    Kaneko, Shiho; Kumatabara, Yusuke; Shimizu, Shoichi; Maruoka, Keiji; Shirakawa, Seiji

    2017-01-01

    Although quaternary ammonium and phosphonium salts are known as important catalysts in phase-transfer catalysis, the catalytic ability of tertiary sulfonium salts has not yet been well demonstrated. Herein, we demonstrate the catalytic ability of trialkylsulfonium salts as hydrogen-bonding catalysts on the basis of the characteristic properties of the acidic α hydrogen atoms on alkylsulfonium salts.

  14. Slab detachment in laterally varying subduction zones: 3-D numerical modeling

    NARCIS (Netherlands)

    Duretz, T.; Gerya, T.V.; Spakman, W.|info:eu-repo/dai/nl/074103164

    Understanding the three-dimensional (3-D) dynamics of subduction-collision systems is a longstanding challenge in geodynamics. We investigate the impact of slab detachment in collision systems that are subjected to along-trench variations. High-resolution thermomechanical numerical models,

  15. Bilateral detachment of the macular neuroepithelium in a patient with Klinefelter syndrome.

    NARCIS (Netherlands)

    Haarlem, J. van; Cruysberg, J.R.M.; Deutman, A.F.

    2003-01-01

    PURPOSE: To describe the occurrence of atypical, bilateral detachment of the macular neuroepithelium and Klinefelter syndrome in a young patient. METHODS: Case report. RESULTS: A 20-year-old male of Chinese origin with karyotype 47,XXY presented with bilateral central neurosensory retinal

  16. Zonal Detached-Eddy Simulation of Turbulent Unsteady Flow over Iced Airfoils

    KAUST Repository

    Zhang, Yue

    2015-07-23

    This paper presentsamultiscale finite-element formulation for the second modeofzonal detached-eddy simulation. The multiscale formulation corrects the lack of stability of the standard Galerkin formulation by incorporating the effect of unresolved scales to the grid (resolved) scales. The stabilization terms arise naturally and are free of userdefined stability parameters. Validation of the method is accomplished via the turbulent flow over tandem cylinders. The boundary-layer separation, free shear-layer rollup, vortex shedding from the upstream cylinder, and interaction with the downstream cylinder are well reproduced. Good agreement with experimental measurements gives credence to the accuracy of zonal detached-eddy simulation in modeling turbulent separated flows. A comprehensive study is then conducted on the performance degradation of ice-contaminated airfoils. NACA 23012 airfoil with a spanwise ice ridge and Gates Learjet Corporation-305 airfoil with a leading-edge horn-shape glaze ice are selected for investigation. Appropriate spanwise domain size and sufficient grid density are determined to enhance the reliability of the simulations. A comparison of lift coefficient and flowfield variables demonstrates the added advantage that the zonal detached-eddy simulation model brings to the Spalart-Allmaras turbulence model. Spectral analysis and instantaneous visualization of turbulent structures are also highlighted via zonal detached-eddy simulation. Copyright © 2015 by the CFD Lab of McGill University. Published by the American Institute of Aeronautics and Astronautics, Inc.

  17. Boundaryless work, psychological detachment and sleep: Does working 'anytime - anywhere' equal employees are 'always on'?

    NARCIS (Netherlands)

    Mellner, C.; Kecklund, L.G.; Kompier, M.A.J.; Sariaslan, A.; Aronsson, G.; Leede, J. de

    2016-01-01

    Employees have gained increased flexibility in organizing their work in time and space, that is boundaryless work. Managing the boundaries between work and personal life would seem to be crucial if one is to psychologically detach from work during leisure in order to unwind and get sufficient sleep.

  18. Retinal detachment associated with thalassemia major and Marfan′s syndrome-A case report

    Directory of Open Access Journals (Sweden)

    Chatterjee Pranab

    1987-01-01

    Full Text Available The thalassaemias, unlike a few other disorders of the haemopoietic system, are very rarely accompanied by ophthalmological changed. Marfan′s Syndrome, on the other hand, exhibits a number of ocular manifestations 2. This article describes a case of uniocular retinal detachment associated with both these conditions

  19. Applicability of Different Hydraulic Parameters to Describe Soil Detachment in Eroding Rills

    NARCIS (Netherlands)

    Wirtz, S.; Seeger, K.M.; Zell, A.; Wagner, C.; Wagner, J.F.; Ries, J.B.

    2013-01-01

    This study presents the comparison of experimental results with assumptions used in numerical models. The aim of the field experiments is to test the linear relationship between different hydraulic parameters and soil detachment. For example correlations between shear stress, unit length shear

  20. The effect of bullying on burnout in nurses: the moderating role of psychological detachment.

    Science.gov (United States)

    Allen, Belinda C; Holland, Peter; Reynolds, Roslyn

    2015-02-01

    The aim of the study was to examine the relationship between bullying and burnout and the potential buffering effect psychological detachment might have on this relationship. There is evidence to suggest that bullying is relatively widespread in the nursing profession, with previous studies indicating that bullying is associated with higher levels of burnout. There is, however, limited research focusing on potential moderators of the relationship between bullying and burnout. A cross-sectional quantitative study conducted with self-completed, anonymous questionnaires. The study was conducted in 2011 with 762 Registered Nurses in Australia. Two hypotheses were tested with validated measures of bullying, psychological detachment and burnout. The hypotheses were tested using hierarchical regression. Bullying is positively associated with burnout. Psychological detachment does not significantly moderate the relationship between bullying and burnout. The results indicate that bullying exacts a strong negative toll on nurses. Ensuring there are workplace policies and practices in place in healthcare organizations to reduce the instances of bullying and proactively address it when it does occur would therefore seem crucial. Individuals may also lower their risk of burning out by psychologically detaching from work. © 2014 John Wiley & Sons Ltd.

  1. Evolving trends in primary retinal detachment repair: microincisional vitrectomy and the role of OCT.

    Science.gov (United States)

    Williams, Patrick D; Hariprasad, Seenu M

    2014-01-01

    Retinal detachment repair continues to evolve toward less invasive techniques that can safely, efficiently, and consistently provide optimal outcomes. In fact, 53% of U.S. respondents to the American Society of Retinal Specialists 2013 Preferences and Trends Survey said they would perform a vitrectomy without scleral buckle to treat a retinal detachment with a superior tear, while 25% would perform pneumatic retinopexy, and 21% would use a scleral buckle with or without vitrectomy.11 Compared to in 2005, many more surgeons prefer vitrectomy-only repair, whereas fewer prefer scleral buckle. Interestingly, preferences toward pneumatic retinopexy have slightly declined, which may reflect increased confidence in vitrectomy surgery to repair a detached retina safely and efficiently as an alternative. Even complex detachments can be treated in a minimally invasive fashion with the improvements in instrumentation, trocars, and oil infusion. While trends will likely continue toward minimal invasiveness, some form of scleral buckle, vitrectomy, and pneumatic retinopexy will all persist as treatment options. OCT advancements may allow for individualized discussions of visual prognosis and surgical decision making without the need for any invasive testing.

  2. Serous Retinal Detachment in Dome-shaped Macula with 7 Years Follow-up.

    Science.gov (United States)

    Alakeely, Adel G; Alrashaed, Saba

    2016-01-01

    Dome-shaped macula (DSM) was first described by Gaucher et al . as a convex protrusion of macula within a staphyloma in highly myopic eyes that cause visual impairment associated with serous foveal detachment (SFD). We describe a patient with persistent SFD in DSM documented by serial spectral domain optical coherence tomography for 7 years with stable vision.

  3. Prediction of bubble detachment diameter in flow boiling based on force analysis

    International Nuclear Information System (INIS)

    Chen Deqi; Pan Liangming; Ren Song

    2012-01-01

    Highlights: ► All the forces acting on the growing bubbles are taken into account in the model. ► The bubble contact diameter has significant effect on bubble detachment. ► Bubble growth force and surface tension are more significant in narrow channel. ► A good agreement between the predicted and the measured results is achieved. - Abstract: Bubble detachment diameter is one of the key parameters in the study of bubble dynamics and boiling heat transfer, and it is hard to be measured in a boiling system. In order to predict the bubble detachment diameter, a theoretical model is proposed based on forces analysis in this paper. All the forces acting on a bubble are taken into account to establish a model for different flow boiling configurations, including narrow and conventional channels, upward, downward and horizontal flows. A correlation of bubble contact circle diameter is adopted in this study, and it is found that the bubble contact circle diameter has significant effect on bubble detachment. A new correlation taking the bubble contact circle diameter into account for the evaluation of bubble growth force is proposed in this study, and it is found that the bubble growth force and surface tension force are more significant in narrow channel when comparing with that in conventional channel. A visual experiment was carried out in order to verify present model; and the experimental data from published literature are used also. A good agreement between predicted and measured results is achieved.

  4. The role of detachment of in-links in scale-free networks

    Czech Academy of Sciences Publication Activity Database

    Lánský, Petr; Polito, F.; Sacerdote, L.

    2014-01-01

    Roč. 47, č. 34 (2014), s. 345002 ISSN 1751-8113 R&D Projects: GA ČR(CZ) GBP304/12/G069 Institutional support: RVO:67985823 Keywords : network * detachment * scale-free Subject RIV: ED - Physiology Impact factor: 1.583, year: 2014

  5. Emotional Autonomy versus Detachment: Revisiting the Vicissitudes of Adolescence and Young Adulthood.

    Science.gov (United States)

    Ryan, Richard M.; Lynch, John H.

    1989-01-01

    Emotional autonomy was examined in three studies of adolescents and young adults. Subjects of the studies were 148 seventh graders, 213 high school students, and 104 undergraduates, respectively. Discussion concerns the conceptualization of attachment versus detachment, dependence, and autonomy in theories of adolescence. (RJC)

  6. Using patient positioning to promote resorption of subretinal fluid in rhegmatogenous retinal detachment before pneumatic retinopexy.

    Science.gov (United States)

    Dorrepaal, Stephen J; Gale, Jeffrey

    2014-03-01

    The purpose of this study was to determine if the volume of subretinal fluid in patients with acute rhegmatogenous retinal detachment may be reduced through patient positioning before pneumatic retinopexy. This was a prospective, masked nonrandomized cohort study examining the change in subretinal fluid volume in patients with rhegmatogenous retinal detachment before and after a 1-hour period of specific head positioning, as measured using B-scan ultrasonography. A series of B-scans, each 2 mm apart in the sagittal plane, were acquired for each eye both before and after the positioning period with the patient lying in a supine position. Ten patients with acute unilateral rhegmatogenous retinal detachment were enrolled. All patients experienced a reduction in subretinal fluid volume, from a mean prepositioning volume of 0.89 ± 0.63 mL to a mean postpositioning volume of 0.45 ± 0.43 mL. The mean relative reduction in subretinal fluid measured as a percentage of prepositioning subretinal fluid volume was 55.4% ± 20%, ranging from 35.3% to 93.5%. In patients with acute rhegmatogenous retinal detachment that fall within the classic indications for pneumatic retinopexy, significant reduction of subretinal fluid volume may be obtained through a 1-hour period of patient positioning in a retinal break-dependent manner.

  7. Lymphocyte bond with 125I-labelled extract of human chorioretina in detached retina patients

    International Nuclear Information System (INIS)

    Smecka, Z.; Stankus, P.

    1982-01-01

    The level is assessed of cellular autoreactivity against retinal antigens in patients with detachment of the retina. A test was selected which can record the first stage of the immunological response, i.e., the bond of sensitized lymphocytes with antigen (mixture of antigens in the form of crude extract), in this case with antigen from the human chorioretina. Two modifications of the test were used: the bond of 125 I-labelled extract from the human chorioretina with isolated lymphocytes, and the bond of the same extract with lymphocytes of whole blood. Using the first modification, a total of 17 patients with detachment of the retina and 17 controls were examined. Usxng the second modification, 15 patients with detachment of the retina and 15 controls were examined. From the results of the test ensued that lymphocytes of patients with detachment of the retina do not differ from lymphocytes of controls in the capacity to bind 125 I-labelled extract from the human chorioretina. The method is described in detail. (author)

  8. Lymphocyte bond with /sup 125/I-labelled extract of human chorioretina in detached retina patients

    Energy Technology Data Exchange (ETDEWEB)

    Smecka, Z.; Stankus, P. (Palackeho Univ., Olomouc (Czechoslovakia). Lekarska Fakulta)

    1982-11-01

    The level is assessed of cellular autoreactivity against retinal antigens in patients with detachment of the retina. A test was selected which can record the first stage of the immunological response, i.e., the bond of sensitized lymphocytes with antigen (mixture of antigens in the form of crude extract), in this case with antigen from the human chorioretina. Two modifications of the test were used: the bond of /sup 125/I-labelled extract from the human chorioretina with isolated lymphocytes, and the bond of the same extract with lymphocytes of whole blood. Using the first modification, a total of 17 patients with detachment of the retina and 17 controls were examined. Using the second modification, 15 patients with detachment of the retina and 15 controls were examined. From the results of the test ensued that lymphocytes of patients with detachment of the retina do not differ from lymphocytes of controls in the capacity to bind /sup 125/I-labelled extract from the human chorioretina. The method is described in detail.

  9. Fibulin 2, a tyrosine O-sulfated protein, is up-regulated following retinal detachment.

    Science.gov (United States)

    Kanan, Yogita; Brobst, Daniel; Han, Zongchao; Naash, Muna I; Al-Ubaidi, Muayyad R

    2014-05-09

    Retinal detachment is the physical separation of the retina from the retinal pigment epithelium. It occurs during aging, trauma, or during a variety of retinal disorders such as age-related macular degeneration, diabetic retinopathy, retinopathy of prematurity, or as a complication following cataract surgery. This report investigates the role of fibulin 2, an extracellular component, in retinal detachment. A major mechanism for detachment resolution is enhancement of cellular adhesion between the retina and the retinal pigment epithelium and prevention of its cellular migration. This report shows that fibulin 2 is mainly present in the retinal pigment epithelium, Bruch membrane, choriocapillary, and to a lesser degree in the retina. In vitro studies revealed the presence of two isoforms for fibulin 2. The small isoform is located inside the cell, and the large isoform is present inside and outside the cells. Furthermore, fibulin 2 is post-translationally modified by tyrosine sulfation, and the sulfated isoform is present outside the cell, whereas the unsulfated pool is internally located. Interestingly, sulfated fibulin 2 significantly reduced the rate of cellular growth and migration. Finally, levels of fibulin 2 dramatically increased in the retinal pigment epithelium following retinal detachment, suggesting a direct role for fibulin 2 in the re-attachment of the retina to the retinal pigment epithelium. Understanding the role of fibulin 2 in enhancing retinal attachment is likely to help improve the current therapies or allow the development of new strategies for the treatment of this sight-threatening condition.

  10. Frequency of lattice degeneration and retinal breaks in the fellow eye in retinal detachment.

    Science.gov (United States)

    Lorentzen, S E

    1988-04-01

    The fellow eye of 100 consecutively admitted cases of retinal detachment was studied with three-mirror examination for the presence of lattice degeneration and retinal breaks. Lattice degeneration was found in 18% and retinal breaks in 20% of fellow eyes.

  11. [Two cases of retinal detachment following laser in Situ keratomileusis repaired by scleral buckling surgery].

    Science.gov (United States)

    Onguchi, Tatsuya; Eshita, Tadahiko; Mita, Shinji; Ishida, Susumu; Shinoda, Kei; Kitamura, Shizuaki; Kawashima, Shinichi; Inoue, Makoto; Oguchi, Yoshihisa; Toda, Ikuko; Kato, Naoko

    2002-02-01

    As laser in situ keratomileusis (LASIK) becomes the treatment of choice in the field of refractive surgery, postoperative rhegmatogenous retinal detachment has also begun to occur. However, since it has not been reported yet here in Japan, we report two cases of retinal detachment following LASIK with suggestions based on our experience. A 34-year-old male(Case 1) and a 26-year-old male(Case 2) suffered from retinal detachment one month and eight months after LASIK, respectively. Contributing retinal breaks were a horseshoe tear in Case 1 and atrophic holes in the lattice degeneration in Case 2. Each patient underwent partial scleral buckling with no intraoperative complication, resulting in successful retinal reattachment. Postoperatively, myopic changes developed and persisted one month in Case 1 and several months in Case 2. Great attention should be paid to the possibility of postoperative myopia after a repair of retinal detachment following LASIK. Thus, we stress the necessity of close cooperation between LASIK surgeons and vitreoretinal surgeons to settle the matter.

  12. LUT Reveals a New Mass-transferring Semi-detached Binary

    Science.gov (United States)

    Qian, S.-B.; Zhou, X.; Zhu, L.-Y.; Zejda, M.; Soonthornthum, B.; Zhao, E.-G.; Zhang, J.; Zhang, B.; Liao, W.-P.

    2015-12-01

    GQ Dra is a short-period eclipsing binary in a double stellar system that was discovered by Hipparcos. Complete light curves in the UV band were obtained with the Lunar-based Ultraviolet Telescope in 2014 November and December. Photometric solutions are determined using the W-D (Wilson and Devinney) method. It is discovered that GQ Dra is a classical Algol-type semi-detached binary where the secondary component is filling the critical Roche lobe. An analysis of all available times of minimum light suggests that the orbital period is increasing continuously at a rate of \\dot{P}=+3.48(+/- 0.23)× {10}-7 days yr-1. This could be explained by mass transfer from the secondary to the primary, which is in agreement with the semi-detached configuration with a lobe-filling secondary. By assuming a conservation of mass and angular momentum, the mass transfer rate is estimated as \\dot{m}=9.57(+/- 0.63)× {10}-8 {M}⊙ {{yr}}-1. All of these results reveal that GQ Dra is a mass-transferring semi-detached binary in a double system that was formed from an initially detached binary star. After the massive primary evolves to fill the critical Roche lobe, the mass transfer will be reversed and the binary will evolve into a contact configuration with two sub-giant or giant component stars.

  13. Negative ion detachment cross sections: Progress report, March 1, 1986-February 28, 1987

    International Nuclear Information System (INIS)

    Champion, R.L.; Doverspike, L.D.

    1986-11-01

    Brief descriptions are given for research performed in (1) the electron detachment of alkali negative ions, (2) collisions of negative ions with alkali atoms, (3) charge exchange involving doubly charged ions, and (4) positive ion production in negative ion-atom collisions

  14. Activation of RhoA and ROCK Are Essential for Detachment of Migrating Leukocytesh

    NARCIS (Netherlands)

    Alblas, J.; Ulfman, L.H.; Hordijk, Peter; Koenderman, L.

    2000-01-01

    Detachment of the rear of the cell from its substratum is an important aspect of locomotion. The signaling routes involved in this adhesive release are largely unknown. One of the few candidate proteins to play a role is RhoA, because activation of RhoA in many cell types leads to contraction, a

  15. Evolution of Outer Retinal Folds Occurring after Vitrectomy for Retinal Detachment Repair

    NARCIS (Netherlands)

    Dell'Omo, Roberto; Tan, H. Stevie; Schlingemann, Reinier O.; Bijl, Heico M.; Lesnik Oberstein, Sarit Y.; Barca, Francesco; Mura, Marco

    2012-01-01

    PURPOSE. To assess the evolution of outer retinal folds (ORFs) occurring after repair of rhegmatogenous retinal detachment (RRD) using spectral domain-optical coherence tomography (sd-OCT) and fundus autofluorescence (FAF), and to discuss their pathogenesis. METHODS. Twenty patients were operated on

  16. Internal Iliac Artery Embolization during an Endovascular Aneurysm Repair with Detachable Interlock Microcoils

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Woo ChuL; Jeon, Yong Sun; Hong, Kee Chun; Cho, Soon Gu; Park, Jae Young [Inha University Hospital, Inha University School of Medicine, Incheon (Korea, Republic of); Kim, Jang Yong [Dept. of Vascular and Endovascular Surgery, The Catholic University of Korea School of Medicine, Seoul (Korea, Republic of)

    2014-10-15

    The purpose of this study was to evaluate the effectiveness of detachable interlock microcoils for an embolization of the internal iliac artery during an endovascular aneurysm repair (EVAR). A retrospective review was conducted on 40 patients with aortic aneurysms, who had undergone an EVAR between January 2010 and March 2012. Among them, 16 patients were referred for embolization of the internal iliac artery for the prevention of type II endoleaks. Among 16 patients, 13 patients underwent embolization using detachable interlock microcoils during an EVAR. Computed tomographic angiographies and clinical examinations were performed during the follow-up period. Technical success, clinical outcome, and complications were reviewed. Internal iliac artery embolizations using detachable interlock microcoils were technically successful in all 13 patients, with no occurrence of procedure-related complications. Follow-up imaging was accomplished in the 13 cases. In all cases, type II endoleak was not observed with computed tomographic angiography during the median follow-up of 3 months (range, 1-27 months) and the median clinical follow-up of 12 months (range, 1-27 months). Two of 13 (15%) patients had symptoms of buttock pain, and one patient died due to underlying stomach cancer. No significant clinical symptoms such as bowel ischemia were observed. Internal iliac artery embolization during an EVAR using detachable interlock microcoils to prevent type II endoleaks appears safe and effective, although this should be further proven in a larger population.

  17. 32 CFR 700.723 - Administration and discipline: Separate and detached command.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Administration and discipline: Separate and... OFFICIAL RECORDS Commanders In Chief and Other Commanders Administration and Discipline § 700.723 Administration and discipline: Separate and detached command. Any flag or general officer in command, any officer...

  18. Aggressiveness of Phytophthora infestans on detached potato leaflets in four Nordic countries

    DEFF Research Database (Denmark)

    Lehtinen, A; Andersson, B; Le, V H

    2009-01-01

    Potato fields in Denmark, Finland, Norway and Sweden were sampled for single-lesion isolates of Phytophthora infestans. The aggressiveness of the isolates was determined on detached leaflets of potato cvs Bintje (susceptible) and Matilda (moderately resistant). The aggressiveness tests were carried...

  19. Coming back to work in the morning: Psychological detachment and reattachment as predictors of work engagement.

    Science.gov (United States)

    Sonnentag, Sabine; Kühnel, Jana

    2016-10-01

    Research has shown that recovery processes in general and psychological detachment in particular are important for work engagement. We argue that work engagement additionally benefits from reattachment to work in the morning (i.e., mentally reconnecting to work before actually starting to work) and that the gains derived from psychological detachment and reattachment are stronger in the morning than in the afternoon. We tested our hypotheses in a daily diary study with a sample of 167 employees who completed 2 surveys per day over the period of 2 workweeks. Hierarchical linear modeling showed that work engagement was higher in the morning than in the afternoon. Evening psychological detachment and morning reattachment positively predicted work engagement throughout the day. The association between reattachment and work engagement was stronger in the morning than in the afternoon. This study demonstrates that not only psychological detachment from work during leisure time, but also reattachment to work when coming back to work are crucial for daily engagement at work. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  20. A numerical study of plasma detachment conditions in JET divertor plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Simonini, R.; Corrigan, G.; Radford, G.; Spence, J.; Taroni, A.; Weber, S. [Commission of the European Communities, Abingdon (United Kingdom). JET Joint Undertaking

    1994-07-01

    Simulation results obtained with the EDGE2D/U code confirm that for a given particle inventory in the SOL (including the divertor), the main parameter determining whether or not particle, momentum and energy detachment occurs, is the residual power P - P{sub lost}, where P is the total power entering the SOL and P{sub lost} is the power lost by transport to walls and by volume losses in the SOL outside the region where detachment takes place. For particle contents leading to reasonable values of the separatrix mid-plane density, detachment is found if the residual power is low enough. Typically the residual power must be inferior to 3 MW for good detachment, with the exact value depending on the geometry of the divertor, the transport assumptions and the neutral recirculation scheme. The results show that divertor plasma conditions relevant for the study of power exhaust and impurity control problems are possible in JET. 9 refs., 2 figs., 1 tab.

  1. Bilateral Asymmetric Rhegmatogenous Retinal Detachment in a Patient with Stickler Syndrome

    Directory of Open Access Journals (Sweden)

    Caner Öztürk

    2018-04-01

    Full Text Available Here we present the long-term anatomical and visual outcomes of bilateral asymmetric rhegmatogenous retinal detachment repair in a patient with Stickler syndrome. A 17-year-old girl presented with decreased visual acuity in both eyes for more than one year. Her best-corrected visual acuity (BCVA was 0.1 in the right eye and 0.05 in the left eye. Slit-lamp anterior segment examination revealed subcapsular cataract in both eyes. Fundus examination showed bilateral rhegmatogenous retinal detachment, chronic retinal detachment accompanied by multiple retinal holes, tears and membranous fibrillary vitreous in the peripheral retina. Grade C2 proliferative vitreoretinopathy was observed in the left eye. Scleral buckling surgery was performed initially for both eyes. After the primary surgical procedure, retinal reattachment was achieved in the right eye and the left eye underwent phacoemulsification, intraocular lens implantation, pars plana vitrectomy (PPV, and silicone oil injection. After these surgical procedures retinal reattachment was achieved in the left eye. Silicone oil removal was performed six months after PPV surgery. After surgical treatment, BCVA was 0.6 in the right eye at the end of the 3.5-year follow-up period. After silicone oil removal, BCVA reached 0.2 in the left eye after 36 months of follow-up and retinal reattachment was achieved in both eyes. Scleral buckling surgery and PPV are effective and confidential methods for the treatment of chronic retinal detachment cases in Stickler syndrome.

  2. Analytical method for determining rill detachment rate of purple soil as compared with that of loess soil

    Science.gov (United States)

    Chen, Xiao-yan; Huang, Yu-han; Zhao, Yu; Mo, Bin; Mi, Hong-xing; Huang, Chi-hua

    2017-06-01

    Rill detachment is an important process in rill erosion. The rill detachment rate is the fundamental basis for determination of the parameters of a rill erosion model. In this paper, an analytical method was proposed to estimate the rill detachment rate. The method is based on the exact analytical solution of rill erosion to the differential equation of rill detachment. The rill sediment concentration distribution as a function of rill length was identified through laboratory experiments under different slope gradients and flow rates. The sediment concentration processes from experiments on loess and purple rills were considered to estimate the rill detachment rates of both soils analytically. They were respectively used as a function of rill length and sediment concentration. The analytical detachment rates were compared with the numerically determined values to verify the analytical methods. The rill detachment rates of the two soils under different flow rates and slope gradients estimated by the analytical method were further compared on the basis of detachment-sediment function and detachment-rill length function. Results indicated that the analytically estimated values were very close to the numerically estimated values. Numerical and analytical methods were equally useful for rill detachment rate estimation. Therefore, the analytical method was verified to be rational and applicable for the rapid determination of the rill detachment rates based on either sediment concentration or rill length. The analytical detachment values of purple and loess soils suggested that the detachment rates of loess soil were significantly and considerably higher than those of purple soil. The erosion potentials of loess soil were also significant higher than those of purple soil. The differences in the erosion of the two soils decreased as the slope gradient and flow rate increased. These observations implied that the degree of loess soil erosion was greater than that of purple

  3. Opinion on Salt intake of Dutch children

    OpenAIRE

    Netherlands Food and Consumer Product Safety Authority

    2009-01-01

    The amount of salt in many, especially commercially prepared, food is too high. Reducing salt intake can contribute positively to public health. A reduction in salt intake at a young age reduces the risk of hypertension and cardiovascular disease in later life. The salt intake of 2-6 year old Dutch children was estimated using the Dutch Food Consumption Survey, which was aimed at children in 2005/2006. The foods that contributed most to the total salt intake were determined.

  4. Necklace-like detachment of endothelial cell layer from arterial wall under low-calcium condition.

    Science.gov (United States)

    Yamaguchi, H; Morisada, M; Kaku, H; Onodera, T; Kurokawa, R

    1994-10-01

    The diversified morphological manifestations in various tissues and organs obtained by administration of differing amounts of calcium chelating agents were reported in previous papers (Yamaguchi et al 1981 a & b; 1982; 1990; 1993). In our recent research described here, administration of a moderate dose of Na2EDTA over the short term demonstrated necklace-like detachment from the arterial wall without disruption of the endothelial cell chain. Intercellular spaces in the media just beneath the detached endothelial cell layer was stained strongly with colloidal iron staining. Electron microscopic observation revealed that the detached endothelial cells showed a lot of elongated anchoring villi from the basal surface, usually seen at the luminal surface, adhered to the degenerative and thin flattened internal elastic lamellae. The alteration of the colloidal iron staining of the vascular wall under the low-calcium condition is suggested to be induced by loosening of the molecular structure of glycosaminoglycans (GAGs) as well as glycoproteins (GPs), comprising the important component of the intercellular matrix and elastic lamellae, which would induce a change in their pasty or viscous character. This would be an accelerative factor for detachment of endothelial cells. Moreover, the lack of the waving of the internal elastic lamellae, trapping of endothelial cytoplasmic processes among them, would play the decisive role in the total detachment of the endothelial cell layer. On the other hand, the low-calcium condition did not adversely influence the joining of endothelial cells. The pathognomatic mechanism will be discussed, with a comparison made to the angiolytic changes provoked by a large amount of Na2EDTA.

  5. Secreted autotransporter toxin (Sat) triggers autophagy in epithelial cells that relies on cell detachment.

    Science.gov (United States)

    Liévin-Le Moal, Vanessa; Comenge, Yannick; Ruby, Vincent; Amsellem, Raymonde; Nicolas, Valérie; Servin, Alain L

    2011-07-01

    The secreted autotransporter toxin, Sat, which belongs to the subfamily of serine protease autotransporters of Enterobacteriaceae, acts as a virulence factor in extraintestinal and intestinal pathogenic strains of Escherichia coli. We observed that HeLa cells exposed to the cell-free culture supernatant of recombinant strain AAEC185p(Sat-IH11128) producing the Sat toxin (CFCS(Sat) ), displayed dramatic disorganization of the F-actin cytoskeleton before loosening cell-to-cell junctions and detachment. Examination of the effect of Sat on GFP-microtubule-associated protein light chain 3 (LC3) HeLa cells revealed that CFCS(Sat) -induced autophagy follows CFCS(Sat) -induced F-actin cytoskeleton rearrangement. The induced autophagy shows an acceleration of the autophagy flux soon after Sat treatment, followed later by a blockade of the flux leading to the accumulation of large GFP-LC3-positive vacuoles in the cell cytoplasm. CFCS(Sat) did not induce cell detachment in autophagy-deficient mouse embryonic fibroblasts in contrast with wild-type mouse embryonic fibroblasts. The CFCS(Sat) -induced large GFP-LC3 dots do not display the characteristics of autophagolysosomes including expression of cathepsin D and Lamp-1 and 2 proteins, and Lysotracker Red- and DQ-BSA-positive labelling. We provide evidences that CFCS(Sat) -induced autophagy is not a cell response intended to get rid of the intracellular toxin. By a pharmacological blockers approach, we found that the blockade of Erk1/2 and p38 MAPKs, but not JNK, inhibited the CFCS(Sat) -induced autophagy and cell detachment whereas phosphatidylinositol-3 kinase blockers inhibiting canonical autophagy were inactive. When attached CFCS(Sat) -treated cells start to detach they showed caspase-independent cell death and rearrangements of the focal adhesion-associated vinculin and paxillin. Collectively, our results support that Sat triggers autophagy in epithelial cells that relies on its cell-detachment effect. © 2011 Blackwell

  6. Structural analysis of how podocytes detach from the glomerular basement membrane under hypertrophic stress

    Directory of Open Access Journals (Sweden)

    Wilhelm eKriz

    2014-12-01

    Full Text Available Podocytes are lost by detachment from the GBM as viable cells; details are largely unknown. We studied this process in the rat after growth stimulation with FGF-2. Endothelial and mesangial cells responded by hyperplasia, podocytes underwent hypertrophy, but, in the long run, developed various changes that could either be interpreted showing progressing stages in detachment from the GBM or stages leading to a tighter attachment by foot process effacement (FPE. This occurred in microdomains within the same podocyte; thus features of detachment and of reinforced attachment may simultaneously be found in the same podocyte.(1 Initially, hypertrophied podocytes underwent cell body attenuation and formed large pseudocysts, i.e. expansions of the subpodocyte space.(2 Podocytes entered the process of FPE starting with the retraction of foot processes and the replacement of the slit diaphragm by occluding junctions thereby sealing the filtration slits. Successful completion of this process led to broad attachments of podocyte cell bodies to the GBM. (3 Failure of sealing the slits led to gaps of varying width between retracting foot processes facilitating the outflow of the filtrate from the GBM.(4 Since those gaps are frequently overarched by broadened primary processes the drainage of the filtrate into the Bowman's space may be hindered leading to the formation of small pseudocysts associated with bare areas of GBM.(5 The merging of pseudocysts created a system of communicating chambers through which the filtrate has to pass to reach Bowman's space. Multiple flow resistances in series likely generated an expansile force on podocytes contributing to detachment.(6 Such a situation appears to proceed to complete disconnection generally of a group of podocytes owing to the junctional connections between them. (7 Since such groups of detaching podocytes generally make contact to parietal cells, they start the formation of tuft adhesions to Bowman's capsule.

  7. Densiron® 68 as an intraocular tamponade for complex inferior retinal detachments

    Directory of Open Access Journals (Sweden)

    Hussain RN

    2011-05-01

    Full Text Available Rumana N Hussain, Somnath BanerjeeLeicester Royal Infirmary, Leicester, UKIntroduction: Densiron® 68 is a high-density liquid used to tamponade inferior retinal detachments. We present a case series of 12 patients treated with Densiron as an intraocular tamponade agent.Methods: A retrospective analysis of 12 eyes in 12 patients was carried out. The primary endpoint was anatomic reattachment of the retina following removal of Densiron oil.Results: All patients had inferior detachments; 33% had associated proliferative vitreoretinopathy (PVR. Densiron was utilized as a primary agent in five patients (42%; the remaining patients had prior unsuccessful surgery for retinal reattachment, including pars plana vitrectomy, cryotherapy, laser, encirclement, gas (C3F8 or C2F6, or silicone oil. Eleven patients (91% had successful reattachment of the retina at 3 months following removal of Densiron; one patient had extensive PVR, total retinal detachment, preretinal macula fibrosis, and chronic hypotony, and surgical intervention was unsuccessful. Six patients (50% had raised intraocular pressure (IOP, resolving in the majority of cases following Densiron removal; two patients had long-term raised IOP requiring topical or surgical therapy. Of the six phakic patients, 50% developed significant cataract in the operated eye. Of those with successful retinal reattachment, visual outcome was variable, with 36% patients gaining two to four lines on Snellen, 27% remaining objectively the same, and 36% losing one to two lines.Conclusion: The anatomic success rate is high (91% in patients requiring Densiron tamponade for inferior retinal detachments with or without evidence of PVR either as a primary or secondary intervention. A common complication is raised IOP; however, this most often resolves following removal of the oil.Keywords: intraocular tamponade, silicone oil, retinal detachment, retinal reattachments

  8. Large-spot subthreshold transpupillary thermotherapy for chronic serous macular detachment

    Directory of Open Access Journals (Sweden)

    Giuseppe Lo Giudice

    2011-03-01

    Full Text Available Giuseppe Lo Giudice1, Valentina de Belvis2, Marco Tavolato1, Alessandro Galan11San Paolo Ophthalmic Center, San Antonio Hospital, Padova, Italy; 2Paediatric Low Vision Center, Paediatric Rare Eye Disease Center, Department of Paediatrics, University of Padova, ItalyPurpose: To report the effect of subthreshold transpupillary thermotherapy (TTT in treating serous detachment of the neurosensory retina secondary to chronic central serous chorioretinopathy (CCSC.Methods: Seven eyes from five patients with CCSC, persistent serous detachment of the neurosensory retina and a clinical course of between 12 and 60 months were treated. All eyes received large-spot TTT guided by indocyanine green angiography (ICGA. Subthreshold TTT was performed using an 810 nm diode laser with a spot size of 3.0 mm (power was set at 350 mW. Treatment was applied for 60 seconds to the areas of choroidal hyperfluorescence on ICGA.Results: The mean number of TTT sessions was 1.4 ± 0.5. All eyes were followed up for at least 6 months (mean 9.6 ± 3.2 standard deviation; range 6–12 months. The mean logarithm of the minimum angle of resolution best-corrected visual acuity was significantly better compared with baseline. All TTT-treated eyes had stable or improved vision (P < 0.001. Mean optical coherence tomography (OCT central foveal thickness was significantly lower in all patients (P < 0.001 compared with pretreatment OCT, with a reduction in subretinal fluid and resolution of serous detachment associated with anatomical fovea restoration. No patient had any treatment-related side effects.Conclusion: Modified subthreshold TTT appears to have a beneficial effect in treating patients with CCSC and persistent neurosensory detachment. The encouraging results and lack of visually significant complications suggest that further investigation is warranted.Keywords: central serous chorioretinopathy, indocyanine green angiography, neurosensory detachment, transpupillary

  9. Anatomical and functional results of primary pars plana vitrectomy in rhegmatogenous retinal detachment.

    Science.gov (United States)

    Gerding, H; Hersener, A

    2013-04-01

    It was the aim of this retrospective study to analyse the anatomical success rate and functional outcome of patients with rhegmatogenous retinal detachments treated primarily by pars plana vitrectomy (PPV). 157 of 200 eyes (79%, 89 phakic (57%), 67 pseudophakic (43%), 1 aphakic) with rhegmatogenous retinal detachment were treated by primary pars plana vitrectomy. 132 cases (84%) completed 6 months, 131 (83%) 12 months, and 108 cases (69%) 24 months of follow-up. Selection of surgical methods was guided by recommendations from the SPR study. Different from these recommendations, phakic eyes were treated by primary PPV if the chance of successful scleral buckling was estimated to be detachment presented during silicon removal. A second surgical intervention for the treatment of re-detachment became necessary in 8 eyes during follow-up. The rate of permanent single-intervention (except silicon removal) attachment was 92.4%. Finally the retina was completely attached in all eyes. Visual acuity improved from a preoperative level of logMAR 1.01 to 0.48 at month 6, 0.40 at month 12 and 0.33 at month 24. Mean final visual acuity at month 24 was 0.32 in phakic eyes and 0.35 in pseudophakic eye (difference not significant). Significant differences in visual acuity were found in relation to the preoperative status of the fovea. The results of this case series, together with the previous published outcome of a cohort treated in the identical study period by scleral buckling, indicate that the outcome of retinal detachment surgery in an average cohort of patients can be expected to be much better than suggested by results of the SPR study. Georg Thieme Verlag KG Stuttgart · New York.

  10. Hypoxia inducible factor 1α contributes to regulation of autophagy in retinal detachment

    Science.gov (United States)

    Shelby, Shameka J.; Angadi, Pavan S.; Zheng, Qiong-Duon; Yao, Jingyu; Jia, Lin; Zacks, David N.

    2015-01-01

    Photoreceptor (PR) cells receive oxygen and nutritional support from the underlying retinal pigment epithelium (RPE). Retinal detachment results in PR hypoxia and their time-dependent death. Detachment also activates autophagy within the PR, which serves to reduce the rate of PR apoptosis. In this study, we test the hypothesis that autophagy activation in the PR results, at least in part, from the detachment-induced activation of hypoxia-inducible factors (HIF). Retina-RPE separation was created in Brown-Norway rats and C57BL/6J mice by injection of 1% hyaluronic acid into the subretinal space. Retinas were harvested and assayed for HIF protein levels. Cultured 661W photoreceptor cells were subjected to hypoxic conditions and assayed for induction of HIF and autophagy. The requirement of HIF-1α and HIF-2α in regulating photoreceptor autophagy was tested using siRNA in vitro and in vivo. We observed increased levels of HIF-1α and HIF-2α within 1 day post-detachment, as well as increased levels of BNIP3, a downstream target of HIF-1α that contributes to autophagy activation. Exposing 661W cells to hypoxia resulted in increased HIF-1α and HIF-2α levels and increase in conversion of LC3-I to LC3-II. Silencing of HIF-1α, but not HIF-2α, reduced the hypoxia-induced increase in LC3-II formation and increased cell death in 661W cells. Silencing of HIF-1α in rat retinas prevented the detachment-induced increase in BNIP3 and LC3-II, resulting in increased PR cell death. Our data support the hypothesis that HIF-1α, but not HIF-2α, serves as an early response signal to induce autophagy and reduce photoreceptor cell death. PMID:26093278

  11. Growth and detachment of single hydrogen bubbles in a magnetohydrodynamic shear flow

    Science.gov (United States)

    Baczyzmalski, Dominik; Karnbach, Franziska; Mutschke, Gerd; Yang, Xuegeng; Eckert, Kerstin; Uhlemann, Margitta; Cierpka, Christian

    2017-09-01

    This study investigates the effect of a magnetohydrodynamic (MHD) shear flow on the growth and detachment of single sub-millimeter-sized hydrogen gas bubbles. These bubbles were electrolytically generated at a horizontal Pt microelectrode (100 μ m in diameter) in an acidic environment (1 M H2SO4 ). The inherent electric field was superimposed by a homogeneous electrode-parallel magnetic field of up to 700 mT to generate Lorentz forces in the electrolyte, which drive the MHD flow. The growth and motion of the hydrogen bubble was analyzed by microscopic high-speed imaging and measurements of the electric current, while particle tracking velocimetry (μ PTV ) and particle image velocimetry (μ PIV ) were applied to measure the surrounding electrolyte flow. In addition, numerical flow simulations were performed based on the experimental conditions. The results show a significant reduction of the bubble growth time and detachment diameter with increasing magnetic induction, which is known to improve the efficiency of water electrolysis. In order to gain further insight into the bubble detachment mechanism, an analysis of the forces acting on the bubble was performed. The strong MHD-induced drag force causes the bubble to slowly slide away from the center of the microelectrode before its detachment. This motion increases the active electrode area and enhances the bubble growth rate. The results further indicate that at large current densities the coalescence of tiny bubbles formed at the foot of the main bubble might play an important role for the bubble detachment. Moreover, the occurrence of Marangoni stresses at the gas-liquid interface is discussed.

  12. Complex shaped detachable platinum coil system for the treatment of cerebral aneurysms: the Codman Trufill DCS and Trufill DCS Orbit Detachable Coil System COMPLEX Registry final results.

    Science.gov (United States)

    Bendok, Bernard R; Rahme, Rudy J

    2013-01-01

    To report on an electronic database with longitudinal information on the use of bare platinum coils for the endovascular occlusion of cerebral aneurysms. We report here the final analysis of the data. From 1 May 2004 to 10 July 2007, a global registry was conducted at 36 centers in the USA, Europe and Latin America. 303 patients were enrolled, of whom 299 patients were treated with bare detachable platinum coils (mostly Trufill Detachable Coil System (DCS) Orbit coils). Short and long term anatomical and clinical data were collected. Logistic regression analysis was used to examine the association of selected patient characteristics to outcomes of recanalization and retreatment. 313 aneurysms, ruptured and unruptured, were treated in the 299 patients. Follow-up data were available on 185 patients: 150 (81%) had a 3-6 month follow-up, 63 (34%) had a 1 year follow-up and five (3%) had a 2 year follow-up. This paper reviews the status of 185 patients with follow-up data available at this time. Immediately postprocedure, 114 (58%) aneurysms were completely obliterated, 40 (20%) residual neck, 23 (12%) residual aneurysm and 19 (10%) dog ear. Of 174 aneurysms in 167 patients with angiographic follow-up, 137 (79%) remained stable or improved, nine (5%) showed aneurysm regrowth, 26 (15%) showed compaction and two (1%) had migrated. At 3-6 months, 11 of the 174 (6%) aneurysms were re-treated. These results confirm previous outcome data of endovascular occlusion of cerebral aneurysms with Trufill DCS Orbit complex shaped detachable platinum coils. Complications related to the device were rare.

  13. Detached concern of forensic mental health nurses in therapeutic relationships with patients the application of the early recognition method related to detached concern.

    Science.gov (United States)

    Fluttert, Frans; van Meijel, Berno; Nijman, Henk; Bjørkly, Stål; Grypdonck, Mieke

    2010-08-01

    Improvement of the interaction between forensic mental health nurses and patients may lead to a reduction of inpatient violence. The concept under study is detached concern, which refers to nurses' skills to neutralize the emotional appeal of patients by a balanced attitude between objectivity and emotional involvement. The Patient Contact Questionnaire (PCQ) aims at measuring the degree of concern of nurses for their patients. The PCQ was applied in a pretest-posttest design, evaluating the effects of the Early Recognition Method (ERM). This method aims at the prevention of inpatient violence in forensic psychiatry. Subjects were 116 forensic mental heath nurses working on 16 wards of a large Dutch forensic hospital. First, the baseline scores were compared to scores reported in an earlier study conducted in general psychiatry. Second, pretest-posttest comparisons were carried out for all nurses, and for subgroups of nurses with regard to gender, educational level, years of working experience, and patient population. Third, pretest-posttest comparisons were made on the PCQ item level. The baseline scores of male nurses indicated significantly higher levels of concern than those of female nurses. In addition, more experienced nurses scored significantly higher with regard to concern than less experienced nurses. When comparing the scores before and after applying ERM, no significant differences were found. However, the sores of female nurses showed a tendency toward more concern after implementation of ERM. Detached concern may be a meaningful concept in forensic mental health nursing in measuring nurses' concern for their patients. Levels of detached concern did not change significantly after application of ERM. However, the application of the PCQ could contribute to a better understanding of the interaction between nurses and their patients. 2010 Elsevier Inc. All rights reserved.

  14. Fracture and Healing of Rock Salt Related to Salt Caverns

    International Nuclear Information System (INIS)

    Chan, K.S.; Fossum, A.F.; Munson, D.E.

    1999-01-01

    In recent years, serious investigations of potential extension of the useful life of older caverns or of the use of abandoned caverns for waste disposal have been of interest to the technical community. All of the potential applications depend upon understanding the reamer in which older caverns and sealing systems can fail. Such an understanding will require a more detailed knowledge of the fracture of salt than has been necessary to date. Fortunately, the knowledge of the fracture and healing of salt has made significant advances in the last decade, and is in a position to yield meaningful insights to older cavern behavior. In particular, micromechanical mechanisms of fracture and the concept of a fracture mechanism map have been essential guides, as has the utilization of continuum damage mechanics. The Multimechanism Deformation Coupled Fracture (MDCF) model, which is summarized extensively in this work was developed specifically to treat both the creep and fracture of salt, and was later extended to incorporate the fracture healing process known to occur in rock salt. Fracture in salt is based on the formation and evolution of microfractures, which may take the form of wing tip cracks, either in the body or the boundary of the grain. This type of crack deforms under shear to produce a strain, and furthermore, the opening of the wing cracks produce volume strain or dilatancy. In the presence of a confining pressure, microcrack formation may be suppressed, as is often the case for triaxial compression tests or natural underground stress situations. However, if the confining pressure is insufficient to suppress fracture, then the fractures will evolve with time to give the characteristic tertiary creep response. Two first order kinetics processes, closure of cracks and healing of cracks, control the healing process. Significantly, volume strain produced by microfractures may lead to changes in the permeability of the salt, which can become a major concern in

  15. Disposal of Radioactive Wastes in Natural Salt

    International Nuclear Information System (INIS)

    Parker, F.L.; Boegly, W.J.; Bradshaw, R.L.; Empson, F.M.; Hemphill, L.; Struxness, E.G.; Tamura, T.

    1960-01-01

    The proposed use of cavities in salt formations as a disposal site for radioactive wastes is based upon : 1. Existence of salt for geologic time periods, 2. The impermeability of salt to the passage of water; 3. The widespread geographical distribution of salt; 4. The extremely large quantities of salt available; 5. The structural strength of salt; 6. The relatively high thermal conductivity of salt in comparison with other general geologic formations; 7. The possible recovery of valuable fission products in the wastes injected into the salt; 8. The relative ease of forming cavities in salt by mining, and the even greater ease and low cost of developing solution cavities in salt; and 9. The low seismicity in the areas of major salt deposits. Radioactive liquid wastes can be stored in cavities in natural salt formations if the structural properties of the salt are not adversely affected by chemical interaction, pressure, temperature, and radiation. Analytical studies show that it is possible to-store 2-year-old 10,000 MWD/T, 800 gal/ton waste in a sphere of 10 ft diameter without exceeding a temperature of 200° F. Laboratory tests show that the structural properties and thermal conductivity of rock salt are not greatly altered by high radiation doses, although high temperatures increase the creep rate for both irradiated and unirradiated samples. Chemical interaction of liquid wastes with salt produces chlorine and other chlorine compound gases, but the volumes are not excessive. The migration of nuclides through the salt and deformation of the cavity and chamber can only be studied in undisturbed salt in situ. One-fifth-scale models have been run in a bedded salt deposit in Hutchinson, Kansas, and full-scale field tests are in progress. (author) [fr

  16. Importance of anisotropy in detachment rates for force production and cargo transport by a team of motor proteins.

    Science.gov (United States)

    Takshak, Anjneya; Kunwar, Ambarish

    2016-05-01

    Many cellular processes are driven by collective forces generated by a team consisting of multiple molecular motor proteins. One aspect that has received less attention is the detachment rate of molecular motors under mechanical force/load. While detachment rate of kinesin motors measured under backward force increases rapidly for forces beyond stall-force; this scenario is just reversed for non-yeast dynein motors where detachment rate from microtubule decreases, exhibiting a catch-bond type behavior. It has been shown recently that yeast dynein responds anisotropically to applied load, i.e. detachment rates are different under forward and backward pulling. Here, we use computational modeling to show that these anisotropic detachment rates might help yeast dynein motors to improve their collective force generation in the absence of catch-bond behavior. We further show that the travel distance of cargos would be longer if detachment rates are anisotropic. Our results suggest that anisotropic detachment rates could be an alternative strategy for motors to improve the transport properties and force production by the team. © 2016 The Protein Society.

  17. Effects of RGD immobilization on light-induced cell sheet detachment from TiO{sub 2} nanodots films

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Kui; Wang, Tiantian [School of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Cyrus Tang Center for Sensor Materials and Applications, Zhejiang University, Hangzhou 310027 (China); Yu, Mengliu [The Affiliated Stomatologic Hospital, Zhejiang University, Hangzhou 310003 (China); The First Affiliated Hospital of Medical College, Zhejiang University, Hangzhou, 310003 (China); Wan, Hongping [School of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Cyrus Tang Center for Sensor Materials and Applications, Zhejiang University, Hangzhou 310027 (China); Lin, Jun [The First Affiliated Hospital of Medical College, Zhejiang University, Hangzhou, 310003 (China); Weng, Wenjian, E-mail: wengwj@zju.edu.cn [School of Materials Science and Engineering, State Key Laboratory of Silicon Materials, Cyrus Tang Center for Sensor Materials and Applications, Zhejiang University, Hangzhou 310027 (China); The Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road, Shanghai 200050 (China); Wang, Huiming, E-mail: hmwang1960@hotmail.com [The Affiliated Stomatologic Hospital, Zhejiang University, Hangzhou 310003 (China); The First Affiliated Hospital of Medical College, Zhejiang University, Hangzhou, 310003 (China)

    2016-06-01

    Light-induced cell detachment is reported to be a safe and effective cell sheet harvest method. In the present study, the effects of arginine–glycine–aspartic acid (RGD) immobilization on cell growth, cell sheet construction and cell harvest through light illumination are investigated. RGD was first immobilized on TiO{sub 2} nanodots films through simple physical adsorption, and then mouse pre-osteoblastic MC3T3-E1 cells were seeded on the films. It was found that RGD immobilization promoted cell adhesion and proliferation. It was also observed that cells cultured on RGD immobilized films showed relatively high level of pan-cadherin. Cells harvested with ultraviolet illumination (365 nm) showed good viability on both RGD immobilized and unmodified TiO{sub 2} nanodot films. Single cell detachment assay showed that cells detached more quickly on RGD immobilized TiO{sub 2} nanodot films. That could be ascribed to the RGD release after UV365 illumination. The current study demonstrated that RGD immobilization could effectively improve both the cellular responses and light-induced cell harvest. - Highlights: • RGD immobilization on TiO{sub 2} nanodots film favors light-induced cell sheet detachment. • Physically adsorbed RGD detaches from the film through ultraviolet illumination. • RGD detachment promotes cells and cell sheets detachment.

  18. Ocular coherence tomographic examination of postoperative foveal architecture after scleral buckling vs vitrectomy for macular off retinal detachment.

    LENUS (Irish Health Repository)

    Gibran, S K

    2012-02-03

    AIMS: This pilot study uses Optical Coherence Tomography (OCT) imaging to compare the difference in foveal architecture after successful retinal detachment (RD) surgery by scleral buckling or pars plana vitrectomy (PPV). METHODS: Prospective recruitment of patients with macular off RDs. Detachment surgery was undertaken by scleral buckling, external drainage, and air injection (group 1) or by PPV (group 2). Postoperatively patients had clinical examinations and OCT at 1, 3, 6, and 12 months. If abnormalities persisted, a further OCT was obtained at 18 months. RESULTS: Retinal reattachment, including clinical macular reattachment, was achieved in all cases within 24 h postoperatively. In group 1 (n=22), postoperative OCT showed persistent foveal detachment in 63% of cases (n=14) at 1 and 3 months. At 6 and 12 months, 36% (n=8) and 9% (n=2) had a persistent foveal detachment, respectively, and at 18 months, foveal detachment eventually. In group 2 (n=21), postoperative OCT showed an attached fovea in all cases; however, foveal thickening suggesting intraretinal oedema was present in all cases. The oedematous appearance of retina on OCT settled in 1-3 months. No foveal abnormality was seen at 6 and 12 months postoperatively. CONCLUSIONS: A high proportion of patients with successful retinal reattachment surgery by scleral buckling had foveal detachments postoperatively. No cases who had PPV had foveal detachments; however, transient retinal oedema was evident in all cases. The aetiology of these changes is unknown and warrants further investigation, as there is the potential of a long-term effect on vision.

  19. Development of rolled joint detachment system for low enriched uranium based advanced heavy water reactor

    Energy Technology Data Exchange (ETDEWEB)

    Chatterjee, S., E-mail: subrata@barc.gov.in; Madhusoodanan, K.

    2014-07-01

    Highlights: • Life limiting mechanism of low enriched uranium based advanced heavy water reactor. • The coolant channels need to be designed as easily replaceable for long life of the reactor. • To meet the above design feature rolled joint detachment system has been developed. • The system works on the principle of shock heating and fast cooling. • The paper describes the design basis and observations from the experimental trials. - Abstract: Advanced heavy water reactor-low enriched uranium (AHWR-LEU) is designed for high discharge burnup and large scale commercial utilization of thorium with LEU as an external feed in a once through fuel cycle. It is a 300 MWe vertical pressure tube type, thorium based reactor, cooled by boiling light water and moderated by heavy water. The reactor incorporates a number of passive safety features and is associated with a fuel cycle having reduced environmental impact and offers more proliferation resistance compared to contemporary light water reactors (LWRs). Some distinguishing features which make AHWR-LEU unique from other conventional nuclear power reactors are core heat removal by natural circulation, negative void coefficient of reactivity under all event scenarios, easily replaceable pressure tubes, long design life, passive safety features, etc. The long design life of the reactor is possible to be met only when the pressure tube which has a limited life of 15–20 full power years (FPYs) due to a life limiting mechanism called irradiation enhanced creep and growth is easily replaceable. Pressure tube is joined at its ends to SS 403 end fittings through rolled joints. A system has been designed and developed for detachment of pressure tubes from the end fitting and its associated hardware without disturbing the surrounding components or coolant channels so that the end fitting can be reused. The system works on the principle of shock heating and fast cooling of the pressure tube in the rolled joint region and

  20. Cell sheet mechanics: How geometrical constraints induce the detachment of cell sheets from concave surfaces.

    Science.gov (United States)

    Yamashita, Tadahiro; Kollmannsberger, Philip; Mawatari, Kazuma; Kitamori, Takehiko; Vogel, Viola

    2016-11-01

    Despite of the progress made to engineer structured microtissues such as BioMEMS and 3D bioprinting, little control exists how microtissues transform as they mature, as the misbalance between cell-generated forces and the strength of cell-cell and cell-substrate contacts can result in unintended tissue deformations and ruptures. To develop a quantitative perspective on how cellular contractility, scaffold curvature and cell-substrate adhesion control such rupture processes, human aortic smooth muscle cells were grown on glass substrates with submillimeter semichannels. We quantified cell sheet detachment from 3D confocal image stacks as a function of channel curvature and cell sheet tension by adding different amounts of Blebbistatin and TGF-β to inhibit or enhance cell contractility, respectively. We found that both higher curvature and higher contractility increased the detachment probability. Variations of the adhesive strength of the protein coating on the substrate revealed that the rupture plane was localized along the substrate-extracellular matrix interface for non-covalently adsorbed adhesion proteins, while the collagen-integrin interface ruptured when collagen I was covalently crosslinked to the substrate. Finally, a simple mechanical model is introduced that quantitatively explains how the tuning of substrate curvature, cell sheet contractility and adhesive strength can be used as tunable parameters as summarized in a first semi-quantitative phase diagram. These parameters can thus be exploited to either inhibit or purposefully induce a collective detachment of sheet-like microtissues for the use in tissue engineering and regenerative therapies. Despite of the significant progress in 3D tissue fabrication technologies at the microscale, there is still no quantitative model that can predict if cells seeded on a 3D structure maintain the imposed geometry while they form a continuous microtissue. Especially, detachment or loss of shape control of growing

  1. 40Ar/39Ar constraints on the activity of the Temsamane extensional detachment (eastern Rif, Morocco)

    Science.gov (United States)

    Jabaloy Sánchez, A.; Booth-Rea, G.; Azdimousa, A.; Asebriy, L.; Vázquez-Vílchez, M.; Martínez-Martínez, J. M.; Gabites, J.

    2012-04-01

    The subducted North Maghrebian passive margin was exhumed by an upper crustal brittle-ductile extensional detachment and brittle low-angle normal faults in a continental subduction transform setting. The Temsamane detachment in the eastern Rif is defined by a ductile shear zone approximately 100 m thick with a low-angle ramp geometry that cuts down into the Temsamane fold-nappe stack. The shear zone shows southwestward kinematics and separates epizone metapelites of the Temsamane units below from the epizone to diagenetic rocks of the Tanger-Ketama-Aknoul units above. To the east, the detachment becomes brittle, branching into a listric-fan that cuts through 10-6 Ma sediments and volcanoclastics in the Tres Forcas cape. New 40Ar/39Ar radiometric ages on amphiboles and micas from the footwall of the Temsamane detachment indicate that the metamorphic peak was reached in the footwall (Temsamane units) at ca. 21 Ma, producing the amphibolite epidote facies in the Ras Afrou Unit. The cooling of the footwall rocks below the 325 °C occurred between the 16 and 13 Ma, while apatite fission track ages indicate that the cooling below the 120 °C occurred at ca. 11 Ma. The 40Ar/39Ar radiometric ages on amphiboles and micas of the metamorphic klippes over the Temsamene units (Ait-Amrâne massif) indicates that the Jurassic marbles of the Tanger-Ketama Unit reached their metamorphic peak at ca. 80 Ma, in agreement with previously published K/Ar ages in micas. The rocks of the Tanger-Ketama Unit cooled below the 120 °C between 17.0 ± 2.4 Ma and 13.9 ± 1.8 Ma. We interpret the increase of cooling rates of the footwall rocks between 15-13 Ma and 11 Ma as due to the activity of the Temsamane detachment fault. Thus, both the North Maghrebian and the South Iberian subducted passive margins were exhumed in the Betic and Rif branches of the Gibraltar arc by SW-directed brittle-ductile detachments during the Late Miocene in an oblique collisional setting.

  2. Scleral buckling for retinal detachment in Ibadan, Sub-Saharan Africa: anatomical and visual outcome

    Directory of Open Access Journals (Sweden)

    Oluleye TS

    2013-05-01

    Full Text Available TS Oluleye, OA Ibrahim, BA OlusanyaRetina and Vitreous Unit, Department of Ophthalmology, University College Hospital, Ibadan, NigeriaBackground: Scleral buckle surgery is not a commonly performed surgical procedure in Sub-Saharan Africa due to a paucity of trained vitreo retinal surgeons. The aim of the study was to review sclera buckle procedures with a view to evaluating the anatomical and visual outcomes.Methods: Case records of patients that had scleral buckle surgery at the Retina Unit of the University College Hospital, Ibadan, Nigeria, between 2007 and 2010 were reviewed. Information retrieved included patients' demographics, duration of symptoms, and presenting vision. Other information included site of retinal break, extent of retinal detachment, involvement of the fellow eye, and macular involvement. Postoperative retina reattachment and postoperative visual acuity were also recorded. Proportions and percentages were used to analyze data.Results: Forty five eyes of 42 patients were studied with a male to female ratio of 1.6:1. The mean age was 47.7 years (±17.6 years. The median duration before presentation was 3 months (range: 5 days – 156 months. Subtotal retinal detachment was found in 35 eyes (77.8% while total retinal detachment occurred in ten eyes (22.2%. Thirty four eyes (75.6% had "macular off" detachments. At 6 weeks, there was an improvement in visual acuity in 23 eyes (51.1%, while visual acuity remained the same in nine eyes (20% and was worse in 13 eyes (28.9%. Anatomical attachment was seen in 43 eyes (95.6% on the operation table, in 40 eyes (90.9% at first day postoperatively and in 32 eyes (86.5% at 6 weeks after surgery.Conclusion: Outcome of sclera buckle surgery for rhegmatogenous retinal detachment may be improved in developing countries of Sub Sahara Africa if adequate awareness is created to educate the populace on early presentation.Keywords: retinal detachment, scleral buckle surgery, anatomical and visual

  3. Intravitreal bevacizumab combined with plaque brachytherapy reduces melanoma tumor volume and enhances resolution of exudative detachment

    Directory of Open Access Journals (Sweden)

    Houston SK

    2013-01-01

    Full Text Available Samuel K Houston,1 Nisha V Shah,1 Christina Decatur,1 Marcela Lonngi,1 William Feuer,1 Arnold M Markoe,2 Timothy G Murray1–31Department of Ophthalmology, 2Department of Radiation Oncology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, 3Murray Ocular Oncology and Retina, Miami, FL, USABackground: The purpose of this study was to evaluate intravitreal bevacizumab as an adjuvant treatment to plaque brachytherapy in the treatment of choroidal melanoma.Methods: This was a retrospective, consecutive study of 124 patients treated from 2007 to 2009 for choroidal melanoma with plaque brachytherapy. Patients were treated with I-125 plaque brachytherapy with 2 mm margins and 85 Gy to the tumor apex. Consecutive patients were injected intravitreally with 2.5 mg/0.1 mL bevacizumab at a site away from the primary tumor and immediately following plaque removal. Choroidal melanomas were observed using indirect ophthalmoscopy, wide-angle photography, and ultrasound. The main outcome measures were tumor volume, resolution of exudative retinal detachment, and visual acuity.Results: One hundred and twenty-four patients met our inclusion criteria and were included in the analysis. The mean patient age was 65.7 years, and the mean apical tumor height was 4.0 ± 2.7 mm and basal diameter was 12.7 ± 3.0 mm. Mean follow-up was 24 months. Prior to treatment, 100% of tumors had exudative retinal detachment, and pretreatment visual acuity was 20/55 (median 20/40. Tumor control was 100%, metastasis was 0% at last follow-up, and 89.8% had complete resolution of exudative retinal detachment, with a mean time to resolution of 3.36 months. At one month, 43% had complete resolution of exudative retinal detachment, which increased to 73% at 4 months. Visual acuity was 20/62 (median 20/40 at 4 months, with stabilization to 20/57 (median 20/40 at 8 months, 20/56 (median 20/30 at 12 months, and 20/68 (median 20/50 at 24 months. Tumor

  4. Simulation of salt production process

    Science.gov (United States)

    Muraveva, E. A.

    2017-10-01

    In this paper an approach to the use of simulation software iThink to simulate the salt production system has been proposed. The dynamic processes of the original system are substituted by processes simulated in the abstract model, but in compliance with the basic rules of the original system, which allows one to accelerate and reduce the cost of the research. As a result, a stable workable simulation model was obtained that can display the rate of the salt exhaustion and many other parameters which are important for business planning.

  5. Production of chlorine from chloride salts

    Science.gov (United States)

    Rohrmann, Charles A.

    1981-01-01

    A process for converting chloride salts and sulfuric acid to sulfate salts and elemental chlorine is disclosed. A chloride salt and sulfuric acid are combined in a furnace where they react to produce a sulfate salt and hydrogen chloride. Hydrogen chloride from the furnace contacts a molten salt mixture containing an oxygen compound of vanadium, an alkali metal sulfate and an alkali metal pyrosulfate to recover elemental chlorine. In the absence of an oxygen-bearing gas during the contacting, the vanadium is reduced, but is regenerated to its active higher valence state by separately contacting the molten salt mixture with an oxygen-bearing gas.

  6. Thermodynamic characterization of salt components for Molten Salt Reactor fuel

    NARCIS (Netherlands)

    Capelli, E.

    2016-01-01

    The Molten Salt Reactor (MSR) is a promising future nuclear fission reactor technology with excellent performance in terms of safety and reliability, sustainability, proliferation resistance and economics. For the design and safety assessment of this concept, it is extremely important to have a

  7. Relationship Between Salt Intake, Salt-Taste Threshold and Blood ...

    African Journals Online (AJOL)

    Conclusion: Sodium intake measured as 24-hour urinary sodium is increased in subjects with hypertension attesting to sodium intake as a risk factor for the development of high blood pressure. Subjects with high salt taste threshold also have increased urinary sodium excretion which may predispose them to deveploment ...

  8. [Evaluation of the macula which was not involved in retinal detachment after surgical treatment of retinal detachment using scleral indentation. Summary of a doctoral thesis].

    Science.gov (United States)

    Boduch-Cieślińska, K

    1992-10-01

    The goal of the study was the evaluation of the influence of the nowadays most frequently used surgical methods in cases of retinal detachment on the macula not involved in the detachment. The study takes into account surgical interventions which have the same indications and principles of action. They are based on an extra-scleral indentation--temporary or permanent one--by means of a Lincoff-Kreissig balloon and a meridional silicone sponge implant. The examinations comprised 54 patients. They were divided into 2 groups: 1st group (24 patients) was treated by cryopexy and a Lincoff-Kreissig balloon, the 2nd group (30 patients) by cryopexy and a meridional silicone sponge implant. In all the patients of both groups the retina reattached. During the 5-years observation of patients of the 1st group no macular changes were detected; one did not observe metamorphopsia or disturbances of the color vision. In the 2nd group instead 17 patients claimed metamorphopsia, 20 patients showed disturbances of the color vision and angiography changes involving the macular region (13 patients).

  9. Molten salt thermal energy storage systems: salt selection

    Energy Technology Data Exchange (ETDEWEB)

    Maru, H.C.; Dullea, J.F.; Huang, V.S.

    1976-08-01

    A research program aimed at the development of a molten salt thermal energy storage system commenced in June 1976. This topical report describes Work performed under Task I: Salt Selection is described. A total of 31 inorganic salts and salt mixtures, including 9 alkali and alkaline earth carbonate mixtures, were evaluated for their suitability as heat-of-fusion thermal energy storage materials at temperatures of 850 to 1000/sup 0/F. Thermophysical properties, safety hazards, corrosion, and cost of these salts were compared on a common basis. We concluded that because alkali carbonate mixtures show high thermal conductivity, low volumetric expansion on melting, low corrosivity and good stability, they are attractive as heat-of-fusion storage materials in this temperature range. A 35 wt percent Li/sub 2/CO/sub 3/-65 wt percent K/sub 2/CO/sub 3/ (50 mole percent Li/sub 2/CO/sub 3/-50 mole percent K/sub 2/CO/sub 3/) mixture was selected as a model system for further experimental work. This is a eutectoid mixture having a heat of fusion of 148 Btu/lb (82 cal/g) that forms an equimolar compound, LiKCO/sub 3/. The Li/sub 2/CO/sub 3/-K/sub 2/CO/sub 3/ mixture is intended to serve as a model system to define heat transfer characteristics, potential problems, and to provide ''first-cut'' engineering data required for the prototype system. The cost of a thermal energy storage system containing this mixture cannot be predicted until system characteristics are better defined. However, our comparison of different salts indicated that alkali and alkaline earth chlorides may be more attractive from a salt cost point of view. The long-term corrosion characteristics and the effects of volume change on melting for the chlorides should be investigated to determine their overall suitability as a heat-of-fusion storage medium.

  10. Imaging findings of spontaneous detachment of the deltoid muscle as a complication of massive rotator cuff tear

    Energy Technology Data Exchange (ETDEWEB)

    Bianchi, Stefano [Institut de Radiologie, Clinique et Fondation des Grangettes, Geneva (Switzerland); Martinoli, Carlo [Istituto di Radiologia, Universita di Genova, Genoa (Italy); Abdelwahab, Ibrahim Fikry [Coney Island Hospital and Downstate School of Medicine, Department of Radiology, New York, New York (United States)

    2006-06-15

    A tear at the origin of the deltoid muscle is uncommon and usually occurs as a complication of shoulder surgery. We report a case of spontaneous deltoid detachment as a complication of massive rotator cuff tear in a 70-year-old woman evaluated by standard radiographs, ultrasound, arthrography and MR-arthrography. We present the multimodality imaging findings with review of the literature. We found that ultrasound is an accurate modality in detecting and assessing spontaneous detachment of the deltoid muscle. As ultrasound is a noninvasive, low-cost, and universally available imaging modality we suggest using ultrasound as the first modality for evaluation of spontaneous detachment of the deltoid muscle. (orig.)

  11. Sources of household salt in South Africa.

    Science.gov (United States)

    Jooste, Pieter L

    2005-01-01

    Marketing of non-iodized salt through unconventional distribution channels is one of the factors weakening the national salt iodization program in South Africa. The aim of this study was therefore to quantify the various sources of household salt, and to relate this information to socio-economic status. Questionnaire information was collected by personal interview during home visits from a multistage, cluster, probability sample of 2164 adults representative of the adult population. Nationally 77.7% of households obtained their table salt from the typical food shops distributing iodized salt. However, in the nine different provinces between 8 and 37.3% of households used unconventional sources, distributing mainly non-iodized salt, to obtain their household salt. These alternative sources include distributors of agricultural salt, small general dealer shops called spaza shops, in peri-urban and rural townships, street vendors and salt saches placed in the packaging of maize meal bags. Country-wide around 30% of low socio-economic households obtained their salt from unconventional sources compared to less than 5% in high socio-economic households, emphasizing the vulnerability of low socio-economic groups to the use of non-iodized salt. Intervention strategies should mobilize all role players involved in unconventional marketing channels of household salt to provide only iodized salt to consumers, as required by law.

  12. Study of Lithium Vapor Flow In a Detached Divertor using DSMC code

    Science.gov (United States)

    Emdee, Eric; Schwartz, Jacob; Goldston, Robert; Jaworski, Michael

    2017-10-01

    A detached divertor is predicted to be necessary to handle the heat fluxes of a demonstration fusion power plant. The lithium vapor box divertor has poloidal baffles to form distinct chambers and contains dense lithium vapor to cause detachment. These chambers would be differentially pumped via condensation, resulting in flow at Knudsen numbers 0.01-0.5 and densities 1019-1023m-3. This divertor geometry is predicted to handle the estimated heat flux while also localizing the vapor in the divertor. We provide a simulation of the divertor's lithium vapor flow using the SPARTA Direct Simulation Monte Carlo (DSMC) code. Lithium mass flow, vapor pressures, and temperatures within each chamber are given. Preliminary simulations of a vapor box divertor similarity experiment are within 30% of an ideal-gas choked nozzle flow calculation. This work supported by DOE Contract No. DE-AC02-09CH11466.

  13. Reoperation for rhegmatogenous retinal detachment as quality indicator for disease management

    DEFF Research Database (Denmark)

    Hajari, Javad N; Christensen, Ulrik; Kiilgaard, Jens F

    2015-01-01

    PURPOSE: To establish a quality indicator that could be used in optimizing treatment for rhegmatogenous retinal detachment (RRD). METHODS: The Danish National Patient Registry was used to identify surgery conducted in Denmark for RRD in the period 01 January 2001-31 December 2009. Cases were...... identified by diagnosis and surgical codes. RESULTS: A total of 6522 cases were operated for a primary RRD in the study period, and 22% (1434 patients) were reoperated for a redetachment. A Cox regression analysis showed that the risk of redetachment was equal to or less than detachment on the fellow eye 1...... year after primary surgery with techniques not using silicone oil. The same was true 1.5 years after surgery for techniques using silicone oil. Based on this, we established a quality indicator defining failure as the need for operation for redetachment within 1 year from initial surgery when using...

  14. OEDGE modeling of DIII-D density scan discharges leading to detachment

    Science.gov (United States)

    Elder, J. D.; Stangeby, P. C.; Bray, B. D.; Brooks, N.; Leonard, A. W.; McLean, A. G.; Unterberg, E. A.; Watkins, J. G.

    2015-08-01

    The OEDGE code is used to model the outer divertor plasma for discharges from a density scan experiment on DIII-D with the objective of assessing EIRENE and ADAS hydrogenic emission atomic physics data for Dα, Dβ and Dγ for values of Te and ne characteristic of the range of divertor plasma conditions from attached to weakly detached. Confidence in these values is essential to spectroscopic interpretation of any experiment or modeling effort. Good agreement between experiment and calculated emissions is found for both EIRENE and ADAS calculated emission profiles, confirming their reliability for plasma conditions down to ∼1 eV. For the cold dense plasma conditions characteristic of detachment, it is found that the calculated emissions are especially sensitive to Te.

  15. OEDGE modeling of DIII-D density scan discharges leading to detachment

    Energy Technology Data Exchange (ETDEWEB)

    Elder, J. D. [Univ. of Toronto, ON (Canada); Stangeby, P. C. [Univ. of Toronto, ON (Canada); General Atomics, San Diego, CA (United States); Bray, B. D. [General Atomics, San Diego, CA (United States); Brooks, N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Leonard, A. W. [General Atomics, San Diego, CA (United States); McLean, A. G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Unterberg, Ezekial A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Watkins, J. G. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-09-30

    Here, we study the OEDGE code that is used to model the outer divertor plasma for discharges from a density scan experiment on DIII-D with the objective of assessing EIRENE and ADAS hydrogenic emission atomic physics data for Dα, Dβ and Dγ for values of Te and ne characteristic of the range of divertor plasma conditions from attached to weakly detached. Confidence in these values is essential to spectroscopic interpretation of any experiment or modeling effort. Good agreement between experiment and calculated emissions is found for both EIRENE and ADAS calculated emission profiles, confirming their reliability for plasma conditions down to ~1 eV. Lastly, for the cold dense plasma conditions characteristic of detachment, it is found that the calculated emissions are especially sensitive to Te.

  16. OEDGE modeling of DIII-D density scan discharges leading to detachment

    Energy Technology Data Exchange (ETDEWEB)

    Elder, J.D., E-mail: david@starfire.utias.utoronto.ca [University of Toronto Institute for Aerospace Studies, Toronto M3H 5T6 (Canada); Stangeby, P.C. [University of Toronto Institute for Aerospace Studies, Toronto M3H 5T6 (Canada); General Atomics, PO Box 85608, San Diego, CA 92186-5608 (United States); Bray, B.D. [General Atomics, PO Box 85608, San Diego, CA 92186-5608 (United States); Brooks, N. [Lawrence Livermore National Laboratory, PO Box 808, Livermore, CA 94550 (United States); Leonard, A.W. [General Atomics, PO Box 85608, San Diego, CA 92186-5608 (United States); McLean, A.G. [Lawrence Livermore National Laboratory, PO Box 808, Livermore, CA 94550 (United States); Unterberg, E.A. [Oak Ridge National Laboratories, P.O. Box 2008, Oak Ridge, TN 37831 (United States); Watkins, J.G. [Sandia National Laboratories, PO Box 5800, Albuquerque, NM 87185 (United States)

    2015-08-15

    The OEDGE code is used to model the outer divertor plasma for discharges from a density scan experiment on DIII-D with the objective of assessing EIRENE and ADAS hydrogenic emission atomic physics data for D{sub α}, D{sub β} and D{sub γ} for values of T{sub e} and n{sub e} characteristic of the range of divertor plasma conditions from attached to weakly detached. Confidence in these values is essential to spectroscopic interpretation of any experiment or modeling effort. Good agreement between experiment and calculated emissions is found for both EIRENE and ADAS calculated emission profiles, confirming their reliability for plasma conditions down to ∼1 eV. For the cold dense plasma conditions characteristic of detachment, it is found that the calculated emissions are especially sensitive to T{sub e}.

  17. Shallow crustal fault rocks from the Black Mountain detachments, Death Valley, CA

    Science.gov (United States)

    Hayman, Nicholas W.

    2006-10-01

    The Black Mountain detachments denuded crystalline footwalls and extended sedimentary hanging walls from late Pliocene to Recent time. Fault rocks include gouges that crosscut breccias, and are in turn cut by compositionally and texturally distinct shear bands. Breccias have cataclastic textures, noteworthy for abundant transgranular fracture and power-law particle size distributions ( D) of 2.77-2.79. Gouges have granular textures, noteworthy for grains with abraded boundaries surrounded by a clay-rich matrix and D = 2.86-3.31. Matrix minerals include phyllosilicates, clay minerals, and oxide aggregates that serve as crude strain indicators. Geochemical data indicate that there was abundant water within the fault zone, but that the water was not plumbed from deeper crustal sources. There are systematic geochemical variations between fault-rock samples, but the inferred mass changes were minor, history of the fault rocks involved multiple deformation mechanisms and authigenic mineral assemblages that hypothetically influenced the frictional properties of the detachment shear zones.

  18. The Northeastern Brazil and Gabon Basins: a Double Rifting System Associated with Multiple Crustal Detachment Surfaces

    Science.gov (United States)

    Castro, Augusto Canellas M., Jr.

    1987-12-01

    Analysis of structural, stratigraphic, and gravimetric data from the Reconcavo, Tucano, and Sergipe-Alagoas basins in northeastern Brazil and the Gabon basin in Africa shows that these basins originated in a double rifting system associated with multiple crustal detachment surfaces and that the direction of dip of the detachment surfaces was reversed at the Vaza-Barris fault system. This geometry is in agreement with models and data from modern rifts, but it requires the existence of a predominantly extensional stress regime in the northern part of the South Atlantic during the early stages of oceanic evolution. Evidence for the existence of such a stress regime is given by application of kinematic constraints to Early Cretaceous reconstructions of the South Atlantic Ocean. Interpretation of the regional geologic setting suggests that the double rifting system and the point of final continental rupture were controlled by the preexisting structural orientation of the tectonic provinces in the Precambrian basement.

  19. Pars plana vitrectomy for retinal detachment due to internal posterior ophthalmomyiasis after cataract extraction.

    Science.gov (United States)

    Billi, B; Lesnoni, G; Audisio, P; Giuliano, M A; Rossi, T; Costi, E; Stirpe, M

    1997-04-01

    The authors report a case of posterior internal ophthalmomyiasis causing vitreous haemorrhage and retinal detachment after uncomplicated cataract extraction. The patient suffered an abrupt vitreous haemorrhage 9 days after ECCE and posterior chamber IOL implantation. After 2 months the haemorrhage did not clear up and a retinal detachment arose. The patient underwent encircling scleral buckle, pars plana vitrectomy and fluid-gas exchange. In course of intervention the surgeon removed from the vitreous chamber a 14-mm-long round worm subsequently identified as a dipterous larva of the Sarcophagidae family. The patient showed no sign of subretinal tracking or retinal breaks or holes. The sclerocorneal surgical wound seems the most likely site of entrance of the parasite, and this would then be the first reported case of myiasis with no RPE tracking.

  20. Detached-eddy simulation of flow around the NREL phase VI blade

    DEFF Research Database (Denmark)

    Johansen, Jeppe; Sørensen, Niels N.; Michelsen, J.A.

    2002-01-01

    The detached-eddy simulation model implemented in the computational fluid dynamics code EllipSys3D is used to calculate the flow around the non-rotating NREL Phase VI wind turbine blade. Results are presented for flow around a parked blade at fixed angle of attack and a blade pitching along...... the blade axis. Computed blade characteristics are compared with experimental data from the NREL/NASA Ames Phase VI unsteady experiment. The detached-eddy simulation model is a method for predicting turbulence in computational fluid dynamics computations, which combines a Reynolds-averaged Navier......-eddy simulation show considerably more three-dimensional flow structures compared to conventional two-equation Reynolds-averaged Navier–Stokes turbulence models, but no particular improvements are seen in the global blade characteristics. Copyright © 2002 John Wiley & Sons, Ltd....

  1. Interventions for asymptomatic retinal breaks and lattice degeneration for preventing retinal detachment.

    Science.gov (United States)

    Wilkinson, Charles P

    2014-09-05

    Asymptomatic retinal breaks and lattice degeneration are visible lesions that are risk factors for later retinal detachment. Retinal detachments occur when fluid in the vitreous cavity passes through tears or holes in the retina and separates the retina from the underlying retinal pigment epithelium. Creation of an adhesion surrounding retinal breaks and lattice degeneration, with laser photocoagulation or cryotherapy, has been recommended as an effective means of preventing retinal detachment. This therapy is of value in the management of retinal tears associated with the symptoms of flashes and floaters and persistent vitreous traction upon the retina in the region of the retinal break, because such symptomatic retinal tears are associated with a high rate of progression to retinal detachment. Retinal tears and holes unassociated with acute symptoms and lattice degeneration are significantly less likely to be the sites of retinal breaks that are responsible for later retinal detachment. Nevertheless, treatment of these lesions frequently is recommended, in spite of the fact that the effectiveness of this therapy is unproven. The objective of this review was to assess the effectiveness and safety of techniques used to treat asymptomatic retinal breaks and lattice degeneration for the prevention of retinal detachment. We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (2014, Issue 2), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE (January 1946 to February 2014), EMBASE (January 1980 to February 2014), PubMed (January 1948 to February 2014), the metaRegister of Controlled Trials (mRCT) (www.controlled-trials.com), ClinicalTrials.gov (www.clinicaltrials.gov) and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We did not use any date or language restrictions in the electronic searches for trials

  2. A systematic review on delayed absorption of subretinal fluid after scleral buckling for rhegmatogenous retinal detachment.

    Science.gov (United States)

    Fu, J L; Shi, G; Liu, Z X; Su, G F; Kang, Z C

    Rhegmatogenous retinal detachment is a vision-threatening disease and is treated by either scleral buckling or pars planar vitrectomy. Rapid absorption of the subretinal fluid (SRF) helps in the early recovery of the vision. The absorption of SRF after the scleral buckling procedure is rapid, provided that the retinal break or breaks are closed at or after surgery. However, in some patients with rhegmatogenous retinal detachment, complete absorption of the SRF occur several weeks or months after the surgery. In this review, we discuss the factors influencing the rate of SRF absorption and the role of delayed absorption on visual recovery. We also discuss the therapeutic options for delayed SRF absorption and the available additional therapeutic options. Knowledge of the factors that influence the rate of SRF absorption, would enable the surgeon to predict the outcomes more accurately.

  3. Recombination and detachment in oxygen discharges: the role of metastable oxygen molecules

    International Nuclear Information System (INIS)

    Gudmundsson, J T

    2004-01-01

    A global (volume averaged) model of oxygen discharges is used to study the transition from a recombination dominated discharge to a detachment dominated discharge. The model includes the metastable oxygen molecules O 2 (a 1 Δ g ) and O 2 (b 1 Σ g + ) and the three Herzberg states O 2 (A 3 Σ u + , A' 3 Δ u , c 1 Σ u - ). Dissociative attachment of the oxygen molecule in the ground state O 2 ( 3 Σ g - ) and the metastable oxygen molecule O 2 (a 1 Δ g ) are the dominating channels for creation of the negative oxygen ion O - . At high pressures, dissociative attachment of the Herzberg states contributes significantly to the creation of the negative oxygen ion, O - . The detachment by a collision of the metastable oxygen molecule O 2 (b 1 Σ g + ) with the oxygen ion, O - , is a significant loss process for the O - at pressures above 10 mTorr. Its contribution to the loss is more significant at a lower applied power, but at the higher pressures it is always significant. Detachment by collision with O( 3 P) is also an important loss mechanism for O - . We find that ion-ion recombination is the dominating loss process for negative ions in oxygen discharges at low pressures and calculate the critical pressure where the contributions of recombination reactions and detachment reactions are equal. This critical pressure depends on the applied power, increases with applied power and is in the range 5-14 mTorr in the pressure and power range investigated

  4. Detachable glass microelectrodes for recording action potentials in active moving organs.

    Science.gov (United States)

    Barbic, Mladen; Moreno, Angel; Harris, Tim D; Kay, Matthew W

    2017-06-01

    Here, we describe new detachable floating glass micropipette electrode devices that provide targeted action potential recordings in active moving organs without requiring constant mechanical constraint or pharmacological inhibition of tissue motion. The technology is based on the concept of a glass micropipette electrode that is held firmly during cell targeting and intracellular insertion, after which a 100-µg glass microelectrode, a "microdevice," is gently released to remain within the moving organ. The microdevices provide long-term recordings of action potentials, even during millimeter-scale movement of tissue in which the device is embedded. We demonstrate two different glass micropipette electrode holding and detachment designs appropriate for the heart (sharp glass microdevices for cardiac myocytes in rats, guinea pigs, and humans) and the brain (patch glass microdevices for neurons in rats). We explain how microdevices enable measurements of multiple cells within a moving organ that are typically difficult with other technologies. Using sharp microdevices, action potential duration was monitored continuously for 15 min in unconstrained perfused hearts during global ischemia-reperfusion, providing beat-to-beat measurements of changes in action potential duration. Action potentials from neurons in the hippocampus of anesthetized rats were measured with patch microdevices, which provided stable base potentials during long-term recordings. Our results demonstrate that detachable microdevices are an elegant and robust tool to record electrical activity with high temporal resolution and cellular level localization without disturbing the physiological working conditions of the organ. NEW & NOTEWORTHY Cellular action potential measurements within tissue using glass micropipette electrodes usually require tissue immobilization, potentially influencing the physiological relevance of the measurement. Here, we addressed this limitation with novel 100-µg detachable

  5. Descemet′s membrane detachment managed with perfluro-n-octane liquid

    Directory of Open Access Journals (Sweden)

    M Ashok Kumar

    2012-01-01

    Full Text Available We report the case of a 68-year-old male who developed Descemet′s membrane detachment after temporal clear corneal phacoemulsification which did not settle with air or viscoelastic injection. The Descemet′s membrane was successfully reattached with restoration of 20/50 vision with the help of perfluro-n-octane liquid. To our knowledge, this is the first such case to be reported.

  6. Structural Discordance Between Neogene Detachments and Frontal Sevier Thrusts, Central Mormon Mountains, Southern Nevada

    Science.gov (United States)

    Wernicke, Brian; Walker, J. Douglas; Beaufait, Mark S.

    1985-02-01

    Detailed geologic mapping in the Mormon Mountains of southern Nevada provides significant insight into processes of extensional tectonics developed within older compressional orogens. A newly discovered, WSW-directed low-angle normal fault, the Mormon Peak detachment, juxtaposes the highest levels of the frontal most part of the east-vergent, Mesozoic Sevier thrust belt with autochthonous crystalline basement. Palinspastic analysis suggests that the detachment initially dipped 20-25° to the west and cut discordantly across thrust faults. Nearly complete lateral removal of the hanging wall from the area has exposed a 5 km thick longitudinal cross-section through the thrust belt in the footwall, while highly attenuated remnants of the hanging wall (nowhere more than a few hundred meters thick) structurally veneer the range. The present arched configuration of the detachment resulted in part from progressive "domino-style" rotation of a few degrees while it was active, but is largely due to rotation on younger, structurally lower, basement-penetrating normal faults that initiated at high-angle. The geometry and kinematics of normal faulting in the Mormon Mountains suggest that pre-existing thrust planes are not required for the initiation of low-angle normal faults, and even where closely overlapped by extensional tectonism, need not function as a primary control of detachment geometry. Caution must thus be exercised in interpreting low-angle normal faults of uncertain tectonic heritage such as those seen in the COCORP west-central Utah and BIRP's MOIST deep-reflection profiles. Although thrust fault reactivation has reasonably been shown to be the origin of a very few low-angle normal faults, our results indicate that it may not be as fundamental a component of orogenic architecture as it is now widely perceived to be. We conclude that while in many instances thrust fault reactivation may be both a plausible and attractive hypothesis, it may never be assumed.

  7. Intangible assets linked to consumers: Acknowledgement and evaluation in the business combination detached from Goodwill

    OpenAIRE

    Spasić Dejan

    2012-01-01

    The development of International Financial Reporting Standards causes new challenges for accounting as a profession. One of those challenges reefers to business combinations treatment in accounting and the related possibility of recognizing intangible assets detached from goodwill. As it usually represents internally generated intangible assets to which the recognition principle cannot be applied according to IAS 38, the author focuses on conditions under which it can be recognized in financi...

  8. Home automation for a sustainable living:modelling a detached house in Northern Finland

    OpenAIRE

    Louis, J.-N. (Jean-Nicolas); Caló, A. (Antonio); Leiviskä, K. (Kauko); Pongrácz, E. (Eva)

    2014-01-01

    Abstract This paper presents a model of a detached house in which home automation has been progressively introduced into the building. The model integrates different factors related to end-user behaviour and decision-making regarding the management of electrical energy consumption, and integrates a gradual end-user response to home automation measures. The presented model aims to show the potential economic benefits obtained by the modelled changes of end-users’ behaviours within a smart e...

  9. A case of Alagille syndrome complicated by intraocular lens subluxation and rhegmatogenous retinal detachment

    OpenAIRE

    Fukumoto, Masanori; Ikeda,Tsunehiko; Sugiyama,Tetsuya; Ueki,Mari; Isizaki,Eisuke; Satou,Takaki

    2013-01-01

    Masanori Fukumoto, Tsunehiko Ikeda, Tetsuya Sugiyama, Mari Ueki, Takaki Sato, Eisuke Ishizaki Department of Ophthalmology, Osaka Medical College, Takatsuki City, Japan Abstract: This case report describes a case of Alagille syndrome with developing intraocular lens subluxation and rhegmatogenous retinal detachment 4 years after cataract surgery. A 15-year-old female patient with Alagille syndrome-associated cataracts in both eyes underwent phacoemulsification aspiration and intraocular lens ...

  10. Infiltration of meteoric water in the South Tibetan Detachment (Mount Everest, Himalaya): When and why?

    Science.gov (United States)

    Gébelin, Aude; Jessup, Micah J.; Teyssier, Christian; Cosca, Michael A.; Law, Richard D.; Brunel, Maurice; Mulch, Andreas

    2017-04-01

    The South Tibetan Detachment (STD) in the Himalayan orogen juxtaposes low-grade Tethyan Himalayan sequence sedimentary rocks over high-grade metamorphic rocks of the Himalayan crystalline core. We document infiltration of meteoric fluids into the STD footwall at 17-15 Ma, when recrystallized hydrous minerals equilibrated with low-δD (meteoric) water. Synkinematic biotite collected over 200 m of structural section in the STD mylonitic footwall (Rongbuk Valley, near Mount Everest) record high-temperature isotopic exchange with D-depleted water (δDwater = -150 ± 5‰) that infiltrated the ductile segment of the detachment most likely during mylonitic deformation, although later isotopic exchange cannot be definitively excluded. These minerals also reveal a uniform pattern of middle Miocene (15 Ma) 40Ar/39Ar plateau ages. The presence of low-δD meteoric water in the STD mylonitic footwall is further supported by hornblende and chlorite with very low δD values of -183‰ and -162‰, respectively. The δD values in the STD footwall suggest that surface-derived fluids were channeled down to the brittle-ductile transition. Migration of fluids from the Earth's surface to the active mylonitic detachment footwall may have been achieved by fluid flow along steep normal faults that developed during synconvergent extension of the upper Tethyan Himalayan plate. High heat flow helped sustain buoyancy-driven fluid convection over the timescale of detachment tectonics. Low δD values in synkinematic fluids are indicative of precipitation-derived fluids sourced at high elevation and document that the ground surface above this section of the STD had already attained similar-to-modern topographic elevations in the middle Miocene.

  11. Clinical characteristics and surgical management of familial exudative vitreoretinopathy-associated rhegmatogenous retinal detachment.

    Science.gov (United States)

    Chen, San-Ni; Hwang, Jiunn-Feng; Lin, Chun-Ju

    2012-02-01

    The purpose of this study was to report the clinical characteristics and surgical outcome of familial exudative vitreoretinopathy-associated rhegmatogenous retinal detachment. Retrospective interventional case series of patients with familial exudative vitreoretinopathy-associated rhegmatogenous retinal detachment. All cases had preoperative and postoperative clinical evaluations. Eyes were divided into three groups: no, moderate, and severe foveal dragging according to the status of fovea. Scleral buckling procedures or vitrectomy was performed to attach the retina. Twenty-four eyes in 22 patients were included in this study. The male to female ratio was 18:4. The average age was 16.42 ± 5.48 years. There were 14, 5, and 5 eyes in the no, moderate, and severe foveal dragging groups, respectively. Proliferative vitreoretinopathy was present in only one eye in the severe foveal dragging group. In the subgroup of eyes without foveal dragging, neither proliferative vitreoretinopathy, posterior located breaks, nor giant tears were noted. All eyes needed only scleral buckle to reattach the retina. In the subgroup with moderate foveal dragging, posterior located break was noted in one eye, which was the only eye in this group that needed vitrectomy besides scleral buckle to attach the retina. In eyes with severe foveal dragging, Stage D proliferative vitreoretinopathy was noted in one eye and posterior located break in one eye. Encircling buckle and vitrectomy were necessary in all eyes. The average number of operation is 1.1, 1.2, and 2.4 for each of the three groups, respectively. Final visual acuity improved in 23 of 24 eyes. Final retinal attachment was obtained in 95.8% of eyes (23 of 24). Male predominance and juvenile onset are the main characteristics in familial exudative vitreoretinopathy-associated rhegmatogenous retinal detachment. Surgical success rates are comparable to rhegmatogenous retinal detachment unassociated with familial exudative

  12. Characteristics and Surgical Outcomes of Rhegmatogenous Retinal Detachment Following Myopic LASIK

    Science.gov (United States)

    Daftarian, Narsis; Dehghan, Mohammad-Hossein; Ahmadieh, Hamid; Soheilian, Masoud; Karkhaneh, Reza; Lashay, Alireza; Mirshahi, Ahmad; Parhizkar, Hamid; Kazemimoghadam, Mohsen; Modarreszadeh, Mehdi; Hashemi, Masih; Fadaei, Mojtaba; Entezari, Morteza

    2009-01-01

    Purpose To describe the clinical features and surgical outcomes of rhegmatogenous retinal detachment (RRD) following myopic laser in situ keratomileusis (LASIK). Methods In a retrospective, non-comparative case series, 46 eyes that had undergone vitreoretinal surgery for management of RRD following myopic LASIK were identified. Data was reviewed with emphasis on characteristics of the RRD, employed surgical techniques, and anatomic and visual outcomes. Results Mean pre-LASIK myopia was −9.7±3.9 (range −4.00 to −18.00) diopters (D). Mean interval between LASIK and development of RRD was 11.6±11.2 months. Posterior vitreous detachment was present in 44 eyes (95.6%). The retinal breaks included flap tears in 36 (78.3%) eyes, giant tears in 8 (17.4%) eyes and atrophic holes in 2 (4.3%) eyes. In eyes with flap tears, the breaks were multiple, large or posterior to the equator in 24(66.7%) eyes. Retinal breaks were related to lattice degeneration in 20 (43.5%) eyes of which, three had history of prophylactic barrier laser photocoagulation. Scleral buckling was performed as the initial procedure in 32 (69.6%) eyes and primary vitrectomy was undertaken in 14 (30.4%) eyes. The initial surgical procedure failed in 14 (30.4%) eyes due to proliferative vitreoretinopathy (PVR). Retinal reattachment was finally achieved in 43 (93.4%) eyes. Postoperative visual acuity ≥20/40 and ≥20/200 was achieved in 16 (34.8%) and 25 (54.3%) eyes, respectively. Conclusion Post-LASIK retinal detachment has a complex nature in eyes with moderate to high myopia. The retinal detachment is complex in terms of size, number and location of retinal breaks, is associated with a high rate of PVR and entails unfavorable visual outcomes. PMID:23198065

  13. Scleral buckling procedure with chandelier illumination for pediatric rhegmatogenous retinal detachment

    OpenAIRE

    Yokoyama, Toshiyuki; Kanbayashi, Koki; Yamaguchi, Tamaki

    2015-01-01

    Toshiyuki Yokoyama, Koki Kanbayashi, Tamaki YamaguchiDepartment of Ophthalmology, Juntendo University Nerima Hospital, Tokyo, JapanPurpose: To assess the treatment of pediatric patients with rhegmatogenous retinal detachment (RRD) by scleral buckling with chandelier illumination.Methods: Three eyes were treated in three patients, healthy boys aged 7 years, 12 years, and 11 years, with RRD, macular involvement, and small retinal holes, of which two were preoperativel...

  14. Intelligent Scheduling of a Grid-Connected Heat Pump in a Danish Detached House

    DEFF Research Database (Denmark)

    Gianniou, Panagiota; Foteinaki, Kyriaki; Heller, Alfred

    This study proposes a methodology for intelligent scheduling of a heat pump installed in a refurbished grid-connected detached house in Denmark. This scheduling is conducted through the coupling of a dynamic building simulation tool with an optimization tool. The optimization of the operation...... thermal comfort conditions. The proposed methodology bridges dynamic building modelling with optimization of real-time operation of HVAC systems offering a detailed model for building physics, especially regarding thermal mass and a stochastic price-based control....

  15. Leading Edge Flame Detachment: Effect on Burning Rate of Ammonium Perchlorate Propellants

    Science.gov (United States)

    Price, E. W.; Chakravarthy, S. R.; Sambamurthi, J. K.; Sigman, R. K.

    1997-01-01

    Inner details of the transition from premixed to diffusion controlled burning are examined by considering the transition at the individual particle flamelet level. These considerations lead to prediction of observable singular burning rate behavior of bimodal AP formulations. Burning rate measurements verify the predictions, supporting the view that particle flamelets become detached and retreat to more remote premixed locations at definite (particles size dependent) pressures, revealed by the burning rate tests.

  16. thermic oil and molten salt

    African Journals Online (AJOL)

    Boukelia T.E, Mecibah M.S and Laouafi A

    1 mai 2016 ... [27] Zavoico, AB. Solar Power Tower Design Basis Document. Tech. rep, Sandia National. Laboratories, SAND2001-2100, 2001. How to cite this article: Boukelia T.E, Mecibah M.S and Laouafi A. Performance simulation of parabolic trough solar collector using two fluids (thermic oil and molten salt).

  17. Salt effects in electromembrane extraction

    DEFF Research Database (Denmark)

    Seip, Knut Fredrik; Jensen, Henrik; Kieu, Thanh Elisabeth

    2014-01-01

    Electromembrane extraction (EME) was performed on samples containing substantial amounts of NaCl to investigate how the presence of salts affected the recovery, repeatability, and membrane current in the extraction system. A group of 17 non-polar basic drugs with various physical chemical...

  18. The fluid mechanics of scleral buckling surgery for the repair of retinal detachment.

    Science.gov (United States)

    Foster, William Joseph; Dowla, Nadia; Joshi, Saurabh Y; Nikolaou, Michael

    2010-01-01

    Scleral buckling is a common surgical technique used to treat retinal detachments that involves suturing a radial or circumferential silicone element on the sclera. Although this procedure has been performed since the 1960s, and there is a reasonable experimental model of retinal detachment, there is still debate as to how this surgery facilitates the re-attachment of the retina. Finite element calculations using the COMSOL Multiphysics system are utilized to explain the influence of the scleral buckle on the flow of sub-retinal fluid in a physical model of retinal detachment. We found that, by coupling fluid mechanics with structural mechanics, laminar fluid flow and the Bernoulli effect are necessary for a physically consistent explanation of retinal reattachment. Improved fluid outflow and retinal reattachment are found with low fluid viscosity and rapid eye movements. A simulation of saccadic eye movements was more effective in removing sub-retinal fluid than slower, reading speed, eye movements in removing subretinal fluid. The results of our simulations allow us to explain the physical principles behind scleral buckling surgery and provide insight that can be utilized clinically. In particular, we find that rapid eye movements facilitate more rapid retinal reattachment. This is contradictory to the conventional wisdom of attempting to minimize eye movements.

  19. Telescoping of isotherms beneath the South Tibetan Detachment System, Mount Everest Massif

    Science.gov (United States)

    Law, R. D.; Jessup, M. J.; Searle, M. P.; Francsis, M. K.; Waters, D. J.; Cottle, J. M.

    2011-11-01

    Petrologic and microstructural/crystal fabric data indicate that isotherms recorded in Greater Himalayan Series (GHS) schists and gneisses in the footwall to the South Tibetan Detachment System (STDS) have undergone extreme telescoping during penetrative flow associated with southward extrusion of the GHS. In the Rongbuk Valley, to the north of Mount Everest, we have made three vertical sampling traverses from the STDS down into the GHS and estimated temperatures associated with penetrative deformation using the opening angles of quartz c-axis fabrics measured on dynamically recrystallized grains. From north to south, the deformation temperature data indicate apparent thermal field gradients of 369, 385 and 420 °C per km for our three traverses, traced over a maximum vertical sampling distance of 0.5 km. Adopting a differential flow path model, simple geometric analysis using sections drawn parallel to the local transport direction indicates that detachment-parallel transport magnitudes of 25-170 km are needed to explain the extreme telescoping of isotherms in the immediate footwall to the STDS, depending on assumed original geothermal gradient, dip of detachment, etc. These particle transport estimates are similar to those previously calculated from barometry data of GHS rocks in the Everest region and are compatible with channel flow models for extrusion and exhumation of the GHS.

  20. Serous retinal detachment following panretinal photocoagulation (PRP) using Pattern Scan Laser (PASCAL) photocoagulator.

    Science.gov (United States)

    Azar, Georges; Wolff, Benjamin; Cornut, Pierre-Loïc; Mauget-Faÿsse, Martine

    2012-01-01

    To report a case of serous retinal detachment after Pattern Scan Laser (PASCAL) treatment in a diabetic woman. A 34-year-old diabetic woman presented with florid diabetic retinopathy after a miscarriage during the 20(th) week of pregnancy. Her Best Corrected Visual Acuity (BCVA) was 20/40 right eye (OD) and 20/30 left eye (OS). Fundus exam showed multiple microaneurysms, large blot hemorrhages and venous dilation both eyes (OU). Fundus fluorescein angiography (FFA) revealed large areas of capillary nonperfusion and panretinal neovascularisation in all quadrants OU. Macular Spectral-Domain Optical Coherence Tomography scan (SD-OCT) did not show any foveal thickening. Panretinal photocoagulation (PRP) was immediately performed OU during the same day. Two days after PASCAL treatment, her BCVA decreased to 20/80 OU and worsened to Count Fingers (CF) during the following days. Fundus exam revealed an extensive serous retinal detachment confirmed on SD-OCT. 2 sub-conjunctival injections of 0.1 ml Betamethasone were done OU. One month later, BCVA improved to 20/30 and SD-OCT confirmed regression of retinal detachment. PASCAL is considered to be a safe treatment, but one has to be aware of its potential side effects. It has to be used with caution in pregnant women.