WorldWideScience

Sample records for pressurized excursion module

  1. Habitat Demonstration Unit (HDU) Pressurized Excursion Module (PEM) Systems Integration Strategy

    Science.gov (United States)

    Gill, Tracy; Merbitz, Jerad; Kennedy, Kriss; Tri, Terry; Toups, Larry; Howe, A. Scott

    2011-01-01

    The Habitat Demonstration Unit (HDU) project team constructed an analog prototype lunar surface laboratory called the Pressurized Excursion Module (PEM). The prototype unit subsystems were integrated in a short amount of time, utilizing a rapid prototyping approach that brought together over 20 habitation-related technologies from a variety of NASA centers. This paper describes the system integration strategies and lessons learned, that allowed the PEM to be brought from paper design to working field prototype using a multi-center team. The system integration process was based on a rapid prototyping approach. Tailored design review and test and integration processes facilitated that approach. The use of collaboration tools including electronic tools as well as documentation enabled a geographically distributed team take a paper concept to an operational prototype in approximately one year. One of the major tools used in the integration strategy was a coordinated effort to accurately model all the subsystems using computer aided design (CAD), so conflicts were identified before physical components came together. A deliberate effort was made following the deployment of the HDU PEM for field operations to collect lessons learned to facilitate process improvement and inform the design of future flight or analog versions of habitat systems. Significant items within those lessons learned were limitations with the CAD integration approach and the impact of shell design on flexibility of placing systems within the HDU shell.

  2. Frequency modulation excursion and rate discrimination in normal-hearing and hearing-impaired listeners

    DEFF Research Database (Denmark)

    Schindwolf, Isabel; Vatti, Marianna; Santurette, Sébastien

    Most natural sounds contain frequency fluctuations over time such as changes in their fundamental frequency, non-periodic speech formant transitions, or periodic fluctuations like musical vibrato. These are sometimes characterized as frequency modulation (FM) with a given excursion (FMe) and rate......, this study investigated the effects of age and SNHL on FMe and FMr difference limens (DLs) for reference values typical of frequency fluctuations observed in speech and music signals....

  3. Author Correction: Reliability and feasibility of gait initiation centre-of-pressure excursions using a Wii® Balance Board in older adults at risk of falling.

    Science.gov (United States)

    Lee, James; Webb, Graham; Shortland, Adam P; Edwards, Rebecca; Wilce, Charlotte; Jones, Gareth D

    2018-05-12

    In the original publication, the article title was incorrectly published as 'Reliability and feasibility of gait initiation centre-of-pressure excursions using a Wii® Balance Board in older adults at risk of failing'. The correct title should read as 'Reliability and feasibility of gait initiation centre-of-pressure excursions using a Wii® Balance Board in older adults at risk of falling'.

  4. Tube to tube excursive instability - sensitivities and transients

    International Nuclear Information System (INIS)

    Brown, M.; Layland, M.W.

    1980-01-01

    A simple basic analysis of excursive instability in a boiler tube shows how it depends upon operating conditions and physical properties. A detailed mathematical model of an AGR boiler is used to conduct a steady state parameter sensitivity survey. It is possible from this basis to anticipate the effects of changes in operating conditions and changes in design parameters upon tube to tube stability. Dynamic responses of tubes operating near the stability threshold are examined using a mathematical model. Simulated excursions are triggered by imparting small abrupt pressure changes on the boiler inlet pressure. The influences of the magnitude of the pressure change, waterside friction factor and gas side coupling between tubes are examined. (author)

  5. Reliability and feasibility of gait initiation centre-of-pressure excursions using a Wii® Balance Board in older adults at risk of falling.

    Science.gov (United States)

    Lee, James; Webb, Graham; Shortland, Adam P; Edwards, Rebecca; Wilce, Charlotte; Jones, Gareth D

    2018-04-17

    Impairments in dynamic balance have a detrimental effect in older adults at risk of falls (OARF). Gait initiation (GI) is a challenging transitional movement. Centre of pressure (COP) excursions using force plates have been used to measure GI performance. The Nintendo Wii Balance Board (WBB) offers an alternative to a standard force plate for the measurement of CoP excursion. To determine the reliability of COP excursions using the WBB, and its feasibility within a 4-week strength and balance intervention (SBI) treating OARF. Ten OARF subjects attending SBI and ten young healthy adults, each performed three GI trials after 10 s of quiet stance from a standardised foot position (shoulder width) before walking forward 3 m to pick up an object. Averaged COP mediolateral (ML) and anteroposterior (AP) excursions (distance) and path-length time (GI-onset to first toe-off) were analysed. WBB ML (0.866) and AP COP excursion (0.895) reliability (ICC 3,1 ) was excellent, and COP path-length reliability was fair (0.517). Compared to OARF, healthy subjects presented with larger COP excursion in both directions and shorter COP path length. OARF subjects meaningfully improved their timed-up-and-go and ML COP excursion between weeks 1-4, while AP COP excursions, path length, and confidence-in-balance remained stable. COP path length and excursion directions probably measure different GI postural control attributes. Limitations in WBB accuracy and precision in transition tasks needs to be established before it can be used clinically to measure postural aspects of GI viably. The WBB could provide valuable clinical evaluation of balance function in OARF.

  6. Cruise tourism shore excursions

    DEFF Research Database (Denmark)

    João Lopes, Maria; Dredge, Dianne

    2018-01-01

    Very complex yet highly integrated business logics characterise cruise tourism with shore excursions frequently identified as a key source of value. This paper presents a case study of cruise tourism and shore excursion planning in Copenhagen, Denmark. The aim of this paper is to investigate...... the characteristics of cruise tourism, itinerary and shore excursion planning with a view to understanding the value generated from cruise tourism shore excursions. We argue that economic value is a blunt measure, and there are other types of value, positive and negative, that are also generated. This research...... reveals that a range of local conditions and structural characteristics create barriers and opportunities for generating different types of value. Using a case study of shore excursions in Copenhagen, the Baltic’s most important port, this paper explains the dynamics between cruise tourism and shore...

  7. Concurrent validity of an automated algorithm for computing the center of pressure excursion index (CPEI).

    Science.gov (United States)

    Diaz, Michelle A; Gibbons, Mandi W; Song, Jinsup; Hillstrom, Howard J; Choe, Kersti H; Pasquale, Maria R

    2018-01-01

    Center of Pressure Excursion Index (CPEI), a parameter computed from the distribution of plantar pressures during stance phase of barefoot walking, has been used to assess dynamic foot function. The original custom program developed to calculate CPEI required the oversight of a user who could manually correct for certain exceptions to the computational rules. A new fully automatic program has been developed to calculate CPEI with an algorithm that accounts for these exceptions. The purpose of this paper is to compare resulting CPEI values computed by these two programs on plantar pressure data from both asymptomatic and pathologic subjects. If comparable, the new program offers significant benefits-reduced potential for variability due to rater discretion and faster CPEI calculation. CPEI values were calculated from barefoot plantar pressure distributions during comfortable paced walking on 61 healthy asymptomatic adults, 19 diabetic adults with moderate hallux valgus, and 13 adults with mild hallux valgus. Right foot data for each subject was analyzed with linear regression and a Bland-Altman plot. The automated algorithm yielded CPEI values that were linearly related to the original program (R 2 =0.99; Pcomputation methods. Results of this analysis suggest that the new automated algorithm may be used to calculate CPEI on both healthy and pathologic feet. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Quaternary magnetic excursions recorded in marine sediments.

    Science.gov (United States)

    Channell, J. E. T.

    2017-12-01

    This year is the golden (50th) anniversary of the first documentation of a magnetic excursion, the Laschamp excursion in volcanics from the Chaine des Puys (Bonhommet and Babkine, 1967). The first recording of an excursion in sediments was from the Blake Outer Ridge (Smith and Foster, 1969). Magnetic excursions are directional aberrations of the geomagnetic field apparently involving short-lived reversal of the main dipole field. They have durations of a few kyrs, and are therefore rarely recorded in sediments with mean sedimentation rates Palma), and 670 ka (Osaka Bay), implying at least 11 excursions in the Brunhes Chron. For the Matuyama Chron, excursions have been recorded in marine sediments at 868 ka (Kamikatsura?), 932 ka (Santa Rosa), 1051 ka (Intra-Jaramillo), 1115 ka (Punaruu), 1255 ka (Bjorn), 1476 ka (Gardar), 1580 ka (Gilsa), and 2737 ka (Porcupine). Excursions coincide with minima in relative paleointensity (RPI) records. Ages are from correlation of excursion records to oxygen isotope records in the same cores, and ice-volume calibration of the oxygen isotope template. The marine sediment record of excursions, combined with independent documentation of excursions in lavas with Ar/Ar age control, is progressively strengthening our knowledge of the excursion inventory in the Quaternary, and enhancing the importance of excursions and RPI in Quaternary stratigraphy.

  9. Power excursion models applied to the study of secundary excursion in sodium cooled fast breeder reactors

    International Nuclear Information System (INIS)

    Messainguiral, Christiane.

    1980-06-01

    An evaluation of the energy that a secondary power excursion could release has been sought throughout the present work. A parametric study was therefore made by means of a power excursion code in fast reactors. The work submitted is therefore made up of the three following parts: Part 1. - (a), the secondary excursion is situated in the generally envisaged programmes and (b) the role of the principal parameters is studied in the calculation effected by the nuclear excursion code that was available at the start of the study. Part 2. - the results obtained for the power excursion calculations made are presented, Part 3. - the insufficient modelling of the reactivity present during the secondary power excursion is deduced from the parametric study just made. A definition is made of the characteristics of a model adapted to the calculation of this hypothetical accident and a new model as worked out within the scope of this work is submitted [fr

  10. Educational role of excursion tourism

    OpenAIRE

    Stanić-Jovanović Sara

    2015-01-01

    Excursion tourism as a mode of travelling to closer destinations has had a long tradition and a cognitive character. Excursions belong to the specific forms of tourism trends and as such, can be viewed in terms of their significant impact on tourist trade within the Serbian tourism market. The demand for this type of tourist travel is constant, thereby highlighting its economic importance. Themed excursions of children in protected areas are developing an interest in nature and are building e...

  11. On excursion increments in heartbeat dynamics

    International Nuclear Information System (INIS)

    Guzmán-Vargas, L.; Reyes-Ramírez, I.; Hernández-Pérez, R.

    2013-01-01

    We study correlation properties of excursion increments of heartbeat time series from healthy subjects and heart failure patients. We construct the excursion time based on the original heartbeat time series, representing the time employed by the walker to return to the local mean value. Next, the detrended fluctuation analysis and the fractal dimension method are applied to the magnitude and sign of the increments in the time excursions between successive excursions for the mentioned groups. Our results show that for magnitude series of excursion increments both groups display long-range correlations with similar correlation exponents, indicating that large (small) increments (decrements) are more likely to be followed by large (small) increments (decrements). For sign sequences and for both groups, we find that increments are short-range anti-correlated, which is noticeable under heart failure conditions

  12. Simulation of power excursions - Osiris reactor; Simulation des excursions de puissance - pile Osiris

    Energy Technology Data Exchange (ETDEWEB)

    Pascouet, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-07-01

    Following the experimental work accomplished in the U.S.A. on Borax 1 and SPERT 1 and the accident of SL 1, the 'Commissariat a l'Energie Atomique' started a research program about the safety of its own swimming Pool reactors, with regard to power excursions. The first research work led to the design of programmed explosive charges, adapted to the simulation of a power excursion. This report describes the application of these methods to the investigation of Osiris safety. (author) [French] A la suite des essais effectues aux U.S.A. sur BORAX 1 et SPERT 1 et de l'accident survenu a SL 1, le Commissariat a l'Energie Atomique a lance un programme d'etudes sur la surete de ses reacteurs piscines vis-a-vis des excursions de puissance. Les premieres etudes ont abouti A la mise au point de charges programmees capables de simuler une excursion de puissance. On trouvera dans le present rapport l'application de ces methodes a l'etude de la surete d'OSIRIS. (auteur)

  13. Educational role of excursion tourism

    Directory of Open Access Journals (Sweden)

    Stanić-Jovanović Sara

    2015-01-01

    Full Text Available Excursion tourism as a mode of travelling to closer destinations has had a long tradition and a cognitive character. Excursions belong to the specific forms of tourism trends and as such, can be viewed in terms of their significant impact on tourist trade within the Serbian tourism market. The demand for this type of tourist travel is constant, thereby highlighting its economic importance. Themed excursions of children in protected areas are developing an interest in nature and are building environmental practices. Thus, children are introduced to the ways of environmental protection, fostering a positive attitude towards the values of preserved natural environment as an opportunity to raise environmental awareness of future generations.

  14. Additive functionals and excursions of Kuznetsov processes

    Directory of Open Access Journals (Sweden)

    Hacène Boutabia

    2005-01-01

    semigroup of transition. In this paper, we give the excursion laws of (Xtt∈ℝ+ conditioned on the strict past and future without duality hypothesis. We study excursions of a general regenerative system and of a regenerative system consisting of the closure of the set of times the regular points of B are visited. In both cases, those conditioned excursion laws depend only on two points Xg− and Xd, where ]g,d[ is an excursion interval of the regenerative set M. We use the (FDt-predictable exit system to bring together the isolated points of M and its perfect part and replace the classical optional exit system. This has been a subject in literature before (e.g., Kaspi (1988 under the classical duality hypothesis. We define an “additive functional” for (Ytt∈ℝ with B, we generalize the laws cited before to (Ytt∈ℝ, and we express laws of pairs of excursions.

  15. A cryogenic multichannel electronically scanned pressure module

    Science.gov (United States)

    Shams, Qamar A.; Fox, Robert L.; Adcock, Edward E.; Kahng, Seun K.

    1992-01-01

    Consideration is given to a cryogenic multichannel electronically scanned pressure (ESP) module developed and tested over an extended temperature span from -184 to +50 C and a pressure range of 0 to 5 psig. The ESP module consists of 32 pressure sensor dice, four analog 8 differential-input multiplexers, and an amplifier circuit, all of which are packaged in a physical volume of 2 x 1 x 5/8 in with 32 pressure and two reference ports. Maximum nonrepeatability is measured at 0.21 percent of full-scale output. The ESP modules have performed consistently well over 15 times over the above temperature range and continue to work without any sign of degradation. These sensors are also immune to repeated thermal shock tests over a temperature change of 220 C/sec.

  16. Educational Excursions in Technical Schools of Pre-revolutionary Russia

    Directory of Open Access Journals (Sweden)

    Timur A. Magsumov

    2013-01-01

    Full Text Available The author, using the data of pre-revolutionary technical schools, traces the genesis and trends of educational excursions development in the Russian Empire. Special attention is attached to the types, organizational forms and methods of excursion activities, educational policy, concerning its development. The article presents author’s classification of educational excursions, notes that educational excursions have become traditional and were operated systematically by the early XX century. Field excursions, which in fact displaced introductive training, prevailed in technical schools

  17. International excursion hydrogeology, Slovakia, [September 8 - 15, 1996

    NARCIS (Netherlands)

    Dijksma, R.

    1996-01-01

    This is a report of the hydrogeological excursion to Slovakia, held in the period from September 8 up to September 15, 1996. This report is a compilation of the work of the participating students, parts of the excursion guide and also information, provided by the Slovak excursion guides.

  18. Method and Apparatus for Characterizing Pressure Sensors using Modulated Light Beam Pressure

    Science.gov (United States)

    Youngquist, Robert C. (Inventor)

    2003-01-01

    Embodiments of apparatuses and methods are provided that use light sources instead of sound sources for characterizing and calibrating sensors for measuring small pressures to mitigate many of the problems with using sound sources. In one embodiment an apparatus has a light source for directing a beam of light on a sensing surface of a pressure sensor for exerting a force on the sensing surface. The pressure sensor generates an electrical signal indicative of the force exerted on the sensing surface. A modulator modulates the beam of light. A signal processor is electrically coupled to the pressure sensor for receiving the electrical signal.

  19. Geomagnetic field evolution during the Laschamp excursion

    Science.gov (United States)

    Leonhardt, Roman; Fabian, Karl; Winklhofer, Michael; Ferk, Annika; Laj, Carlo; Kissel, Catherine

    2009-02-01

    Since the last geomagnetic reversal, 780,000 years ago, the Earth's magnetic field repeatedly dropped dramatically in intensity. This has often been associated with large variations in local field direction, but without a persistent global polarity flip. The structure and dynamics of geomagnetic excursions, and especially the difference between excursions and polarity reversals, have remained elusive so far. For the best documented excursion, the Laschamp event at 41,000 years BP, we have reconstructed the evolution of the global field morphology by using a Bayesian inversion of several high-resolution palaeomagnetic records. We have obtained an excursion scenario in which inverse magnetic flux patches at the core-mantle boundary emerge near the equator and then move poleward. Contrary to the situation during the last reversal (Leonhardt, R., Fabian, K., 2007. Paleomagnetic reconstruction of the global geomagnetic field evolution during the Matuyama/Brunhes transition: Iterative Bayesian inversion and independent verification. Earth Planet. Sci. Lett. 253, 172-195), these flux patches do not cross the hydrodynamic boundary of the inner-core tangent cylinder. While the last geomagnetic reversal began with a substantial increase in the strength of the non-dipolar field components, prior to the Laschamp excursion, both dipolar and non-dipolar field decay at the same rate. This result suggests that the nature of an upcoming geomagnetic field instability can be predicted several hundred years in advance. Even though during the Laschamp excursion the dipolar field at the Earth's surface was dominant, the reconstructed dynamic non-dipolar components lead to considerable deviations among predicted records at different locations. The inverse model also explains why at some locations no directional change during the Laschamp excursion is observed.

  20. Flow-excursion-induced dryout at low-heat-flux

    International Nuclear Information System (INIS)

    Khatib-Rahbar, M.; Cazzoli, E.G.

    1983-01-01

    Flow-excursion-induced dryout at low-heat-flux natural-convection boiling, typical of liquid-metal fast-breeder reactors, is addressed. Steady-state calculations indicate that low-quality boiling is possible up to the point of Ledinegg instability leading to flow excursion and subsequent dryout in agreement with experimental data. A flow-regime-dependent dryout heat flux relationship based upon saturated boiling criterion is also presented. Transient analysis indicates that premature flow excursion can not be ruled out and sodium boiling is highly transient dependent. Analysis of a high-heat-flux forced convection, loss-of-flow transient shows a significantly faster flow excursion leading to dryout in excellent agreement with parallel calculations using the two-dimensional THORAX code. 17 figures

  1. K-Ar ages of the Auckland geomagnetic excursions

    International Nuclear Information System (INIS)

    Mochizuki, Nobutatsu; Tsunakawa, Hideo; Shibuya, Hidetoshi; Tagami, Takahiro; Ozawa, Ayako; Cassidy, John; Smith, E.M.

    2004-01-01

    K-Ar age determinations were made on two monogenetic volcanoes in the Auckland volcanic field, New Zealand, which have recorded the Auckland geomagnetic excursions. For the Wiri volcano with the north-down intermediate paleomagnetic direction, five samples gave a weighted mean age of 27±5 (1σ) ka. For the Hampton Park volcano with the west-up intermediate direction, three samples gave a weighted mean of 55±5(1σ) ka. Since these two K-Ar ages are distinguished at 2σ level, it is inferred that at least two geomagnetic excursions can be recognized in Auckland. The age of the Hampton Park is barely distinguished from the established age range of the Laschamp excursion (39-45 ka) at 2σ level. The age of the Wiri coincides with the age of c. 30 ka in which excursions have been found from sedimentary and volcanic records. The reported excursions from volcanic rocks show a VGP cluster in the central to northern Pacific region which is distinct from the VGP paths or clusters during polarity reversals. (author)

  2. Pressure tracking control of vehicle ABS using piezo valve modulator

    Science.gov (United States)

    Jeon, Juncheol; Choi, Seung-Bok

    2011-03-01

    This paper presents a wheel slip control for the ABS(anti-lock brake system) of a passenger vehicle using a controllable piezo valve modulator. The ABS is designed to optimize for braking effectiveness and good steerability. As a first step, the principal design parameters of the piezo valve and pressure modulator are appropriately determined by considering the braking pressure variation during the ABS operation. The proposed piezo valve consists of a flapper, pneumatic circuit and a piezostack actuator. In order to get wide control range of the pressure, the pressure modulator is desired. The modulator consists of a dual-type cylinder filled with different substances (fluid and gas) and a piston rod moving vertical axis to transmit the force. Subsequently, a quarter car wheel slip model is formulated and integrated with the governing equation of the piezo valve modulator. A sliding mode controller to achieve the desired slip rate is then designed and implemented. Braking control performances such as brake pressure and slip rate are evaluated via computer simulations.

  3. Towards a global view of the Laschamp excursion

    Science.gov (United States)

    Laj, C.; Kissel, C.; Leonhardt, R.; Fabian, K.; Winklhofer, M.; Ferk, A.; Ninnemann, U.

    2009-04-01

    A new record of a geomagnetic excursion has been obtained from Core MD07-3128 taken at (75° 34' W ; 52° 40' S) off the Pacific coast of Southern Chile, during the IMAGES XV-MD159-PACHIDERME cruise of the R/V Marion Dufresne (IPEV). Radiocarbon datings extend for the moment to 36.3 kyr BP at 18 meters. Linear extrapolation of the last 2 dates downcore, gives an age of 40.7 for the middle point of the excursion at 20.5 m. This age is virtually identical to the most precise and reliable dating of the Laschamp excursion (obtained by K/Ar and 40Ar/39Ar) at the type locality at Laschamp, where Norbert Bonhommet first discovered the excursion during his PhD research work. We therefore consider that we have obtained a new record of the Laschamp Excursion. Because of the extraordinarily high sediment accumulation rate, the directional excursion is recorded over about 2 meters of sediment (between 19,65 and 21,5) and corresponds to a prolonged marked low in the relative paleointensity record. Details of the directional and relative paleointensity changes will be discussed. The high southern latitude at which this new record was obtained and its very detailed nature make it ideal to further constrain the inverse model of the Laschamp Excursion (IMOLEe) (Leonhardt et al. EPSL in press). The results obtained when these new data are considered in the model will be discussed in terms of dipolar versus non-dipolar components of the transistional field and comparison between predicted (modeled) and observed directions at all the sites used for the construction of this last version of the inverse model (IMOLEf).

  4. Buoyancy-driven flow excursions in fuel assemblies

    International Nuclear Information System (INIS)

    Laurinat, J.E.; Paul, P.K.; Menna, J.D.

    1995-01-01

    A power limit criterion was developed for a postulated Loss of Pumping Accident (LOPA) in one of the recently shut down heavy water production reactors at the Savannah River Site. These reactors were cooled by recirculating moderator downward through channels in cylindrical fuel tubes. Powers were limited to prevent a flow excursion from occurring in one or more of these parallel channels. During full-power operation, limits prevented a boiling flow excursion from taking place. At low flow rates, during the addition of emergency cooling water, buoyant forces reverse the flow in one of the coolant channels before boiling occurs. As power increases beyond the point of flow reversal, the maximum wall temperature approaches the fluid saturation temperature, and a thermal excursion occurs. The power limit criterion for low flow rates was the onset of flow reversal. To determine conditions for flow reversal, tests were performed in a mock-up of a fuel assembly that contained two electrically heated concentric tubes surrounded by three flow channels. These tests were modeled using a finite difference thermal-hydraulic code. According to code calculations, flow reversed in the outer flow channel before the maximum wall temperature reached the local fluid saturation temperature. Thermal excursions occurred when the maximum wall temperature approximately equaled the saturation temperature. For a postulated LOPA, the flow reversal criterion for emergency cooling water addition was more limiting than the boiling excursion criterion for full power operation. This criterion limited powers to 37% of historical levels

  5. Neutronics simulations on hypothetical power excursion and possible core melt scenarios in CANDU6

    International Nuclear Information System (INIS)

    Kim, Yonghee

    2015-01-01

    LOCA (Loss of coolant accident) is an outstanding safety issue in the CANDU reactor system since the coolant void reactivity is strongly positive. To deal with the LOCA, the CANDU systems are equipped with specially designed quickly-acting secondary shutdown system. Nevertheless, the so-called design-extended conditions are requested to be taken into account in the safety analysis for nuclear reactor systems after the Fukushima accident. As a DEC scenario, the worst accident situation in a CANDU reactor system is a unprotected LOCA, which is supposed to lead to a power excursion and possibly a core melt-down. In this work, the hypothetical unprotected LOCA scenario is simulated in view of the power excursion and fuel temperature changes by using a simplified point-kinetics (PK) model accounting for the fuel temperature change. In the PK model, the core reactivity is assumed to be affected by a large break LOCA and the fuel temperature is simulated to account for the Doppler effect. In addition, unlike the conventional PK simulation, we have also considered the Xe-I model to evaluate the impact of Xe during the LOCA. Also, we tried to simulate the fuel and core melt-down scenario in terms of the reactivity through a series of neutronics calculations for hypothetical core conditions. In case of a power excursion and possible fuel melt-down situation, the reactor system behavior is very uncertain. In this work, we tried to understand the impacts of fuel melt and relocation within the pressure vessel on the core reactivity and failure of pressure and calandria tubes. (author)

  6. Buoyancy-driven flow excursions in fuel assemblies

    International Nuclear Information System (INIS)

    Laurinat, J.E.; Paul, P.K.; Menna, J.D.

    1995-01-01

    A power limit criterion was developed for a postulated Loss of Pumping Accident (LOPA) in one of the recently shut down heavy water production reactors at the Savannah River Site. These reactors were cooled by recirculating heavy water moderator downward through channels in cylindrical fuel tubes. Powers were limited to safeguard against a flow excursion in one of more of these parallel channels. During-full-power operation, limits safeguarded against a boiling flow excursion. At low flow rates, during the addition of emergency cooling water, buoyant forces reverse the flow in one of the coolant channels before boiling occurs. As power increased beyond the point of flow reversal, the maximum wall temperature approaches the fluid saturation temperature, and a thermal excursion occurs. The power limit criterion for low flow rates was the onset of flow reversal. To determine conditions for flow reversal, tests were performed in a mock-up of a fuel assembly that contained two electrically heated concentric tubes surrounded by three flow channels. These tests were modeled using a finite difference thermal-hydraulic code. According to code calculations, flow reversed in the outer flow channel before the maximum wall temperature reached the local fluid saturation temperature. Thermal excursions occurred when the maximum wall temperature approximately equaled the saturation temperature. For a postulated LOPA, the flow reversal criterion for emergency cooling water addition was more limiting than the boiling excursion criterion for full power operation. This criterion limited powers to 37% of the limiting power for previous long-term reactor operations

  7. Buoyancy-driven flow excursions in fuel assemblies

    Energy Technology Data Exchange (ETDEWEB)

    Laurinat, J.E.; Paul, P.K.; Menna, J.D. [Westinghouse Savannah River Company, Aiken, SC (United States)

    1995-09-01

    A power limit criterion was developed for a postulated Loss of Pumping Accident (LOPA) in one of the recently shut down heavy water production reactors at the Savannah River Site. These reactors were cooled by recirculating heavy water moderator downward through channels in cylindrical fuel tubes. Powers were limited to safeguard against a flow excursion in one of more of these parallel channels. During-full-power operation, limits safeguarded against a boiling flow excursion. At low flow rates, during the addition of emergency cooling water, buoyant forces reverse the flow in one of the coolant channels before boiling occurs. As power increased beyond the point of flow reversal, the maximum wall temperature approaches the fluid saturation temperature, and a thermal excursion occurs. The power limit criterion for low flow rates was the onset of flow reversal. To determine conditions for flow reversal, tests were performed in a mock-up of a fuel assembly that contained two electrically heated concentric tubes surrounded by three flow channels. These tests were modeled using a finite difference thermal-hydraulic code. According to code calculations, flow reversed in the outer flow channel before the maximum wall temperature reached the local fluid saturation temperature. Thermal excursions occurred when the maximum wall temperature approximately equaled the saturation temperature. For a postulated LOPA, the flow reversal criterion for emergency cooling water addition was more limiting than the boiling excursion criterion for full power operation. This criterion limited powers to 37% of the limiting power for previous long-term reactor operations.

  8. Random-process excursions in radioisotope instruments

    International Nuclear Information System (INIS)

    Galochkin, D.V.; Polovko, S.A.

    1984-01-01

    Approximate expressions are derived for the mathematical expectation, variance, and distribution of the durations of the excursions of the output signal from a ratemeter in a radioisotope relay instrument. The tabulated comparison of results from Monte Carlo simulation and analytical calculation shows good agreement over the mean value and the variance of the excursion duration for T 0.2 sec as calculated and as obtained by Monte Carlo simulation with a computer using 5000 realizations. It is suggested that the results should be used in choosing the optimum parameters of radioisotope relay instruments

  9. Compensation for large thorax excursions in EIT imaging.

    Science.gov (United States)

    Schullcke, B; Krueger-Ziolek, S; Gong, B; Mueller-Lisse, U; Moeller, K

    2016-09-01

    Besides the application of EIT in the intensive care unit it has recently also been used in spontaneously breathing patients suffering from asthma bronchiole, cystic fibrosis (CF) or chronic obstructive pulmonary disease (COPD). In these cases large thorax excursions during deep inspiration, e.g. during lung function testing, lead to artifacts in the reconstructed images. In this paper we introduce a new approach to compensate for image artifacts resulting from excursion induced changes in boundary voltages. It is shown in a simulation study that boundary voltage change due to thorax excursion on a homogeneous model can be used to modify the measured voltages and thus reduce the impact of thorax excursion on the reconstructed images. The applicability of the method on human subjects is demonstrated utilizing a motion-tracking-system. The proposed technique leads to fewer artifacts in the reconstructed images and improves image quality without substantial increase in computational effort, making the approach suitable for real-time imaging of lung ventilation. This might help to establish EIT as a supplemental tool for lung function tests in spontaneously breathing patients to support clinicians in diagnosis and monitoring of disease progression.

  10. Develoment of pressure drop calculation modules for a wire-wrapped LMR subassembly

    International Nuclear Information System (INIS)

    Kim, Young Gyun; Lim, Hyun Jin; Kim, Won Seok; Kim, Young Il

    2000-06-01

    Pressure drop calculation modules for a wire-wrapped LMR subassembly was been developed. This report summarizes present information on pressure drop calculation modules for inlet hole, lower part and upper part of a wire-wrapped LMR subassembly which was developed using simple formulas of sudden expansion and sudden contraction. A case calculation study was done using design data of a KALIMER driver fuel subassembly. And the total pressure drop in the driver fuel subassembly, except for the bundle part, was calculated as 0.13 MPa, which is in the reasonable pressure drop range. The developed modules will be integrated in the total subassembly pressure drop calculation code with further improvements

  11. Hydrodynamic analysis of the LMFBR prompt burst excursion (PBE) experiment

    International Nuclear Information System (INIS)

    Young, M.F.

    1977-01-01

    A series of in-pile experiments has been conducted at Sandia Laboratories to provide information on pressure levels and conversion of thermal energy into mechanical work in LMFBR cores during hypothetical, superprompt-critical excursions. Pressures generated in these experiments are recorded by a pressure transducer located at the top and bottom of a sodium channel surrounding a single, fresh UO 2 fuel pin. Work energy conversion is measured by a linear motion transducer connected to a piston at the top of the sodium column. Since the pressure transducers are located fairly far from the location of pin failure, it becomes necessary to determine the effect of channel geometry and piston motion on the observed pressure data. A two-dimensional, hydrodynamic analysis of pressure pulse propagation in the fuel pin-coolant channel geometry was therefore performed using the CSQII computer code. The initial series of PBE experiments consists of single, fresh UO 2 pins surrounded by a sodium-filled or dry-coolant channel contained in a closed test capsule. The capsule is subjected to a maximum pulse in the Annular Core Pulse Reactor (ACPR) resulting in an energy deposition of from 2350 to 2900 J/g (14 and 20 percent enriched pins). The pulse width at half maximum (PWHM) is about 5 ms

  12. ORION - Crew Module Side Hatch: Proof Pressure Test Anomaly Investigation

    Science.gov (United States)

    Evernden, Brent A.; Guzman, Oscar J.

    2018-01-01

    The Orion Multi-Purpose Crew Vehicle program was performing a proof pressure test on an engineering development unit (EDU) of the Orion Crew Module Side Hatch (CMSH) assembly. The purpose of the proof test was to demonstrate structural capability, with margin, at 1.5 times the maximum design pressure, before integrating the CMSH to the Orion Crew Module structural test article for subsequent pressure testing. The pressure test was performed at lower pressures of 3 psig, 10 psig and 15.75 psig with no apparent abnormal behavior or leaking. During pressurization to proof pressure of 23.32 psig, a loud 'pop' was heard at 21.3 psig. Upon review into the test cell, it was noted that the hatch had prematurely separated from the proof test fixture, thus immediately ending the test. The proof pressure test was expected be a simple verification but has since evolved into a significant joint failure investigation from both Lockheed Martin and NASA.

  13. Excursion Processes Associated with Elliptic Combinatorics

    Science.gov (United States)

    Baba, Hiroya; Katori, Makoto

    2018-06-01

    Researching elliptic analogues for equalities and formulas is a new trend in enumerative combinatorics which has followed the previous trend of studying q-analogues. Recently Schlosser proposed a lattice path model in the square lattice with a family of totally elliptic weight-functions including several complex parameters and discussed an elliptic extension of the binomial theorem. In the present paper, we introduce a family of discrete-time excursion processes on Z starting from the origin and returning to the origin in a given time duration 2 T associated with Schlosser's elliptic combinatorics. The processes are inhomogeneous both in space and time and hence expected to provide new models in non-equilibrium statistical mechanics. By numerical calculation we show that the maximum likelihood trajectories on the spatio-temporal plane of the elliptic excursion processes and of their reduced trigonometric versions are not straight lines in general but are nontrivially curved depending on parameters. We analyze asymptotic probability laws in the long-term limit T → ∞ for a simplified trigonometric version of excursion process. Emergence of nontrivial curves of trajectories in a large scale of space and time from the elementary elliptic weight-functions exhibits a new aspect of elliptic combinatorics.

  14. Disk Disruptions and X-ray Intensity Excursions in Cyg X-2, LMC X-3 and Cyg X-3

    Science.gov (United States)

    Boyd, P. T.; Smale, A. P.

    2001-05-01

    The RXTE All Sky Monitor soft X-ray light curves of many X-ray binaries show long-term intensity variations (a.k.a "superorbital periodicities") that have been ascribed to precession of a warped, tilted accretion disk around the X-ray source. We have found that the excursion times between X-ray minima in Cyg X-2 can be characterized as a series of integer multiples of the 9.8 binary orbital period, (as opposed to the previously reported stable 77.7 day single periodicity, or a single modulation whose period changes slowly with time). While the data set is too short for a proper statistical analysis, it is clear that the length of any given intensity excursion cannot be used to predict the next (integer) excursion length in the series. In the black hole candidate system LMC X-3, the excursion times are shown to be related to each other by rational fractions. We find that the long term light curve of the unusual galactic X-ray jet source Cyg X-3 can also be described as a series of intensity excursions related to each other by integer multiples of a fundamental underlying clock. In the latter cases, the clock is apparently not related to the known binary periods. A unified physical model, involving both an inclined accretion disk and a fixed-probability disk disruption mechanism is presented, and compared with three-body scattering results. Each time the disk passes through the orbital plane it experiences a fixed probability P that it will disrupt. This model has testable predictions---the distribution of integers should resemble that of an atomic process with a characteristic half life. Further analysis can support or refute the model, and shed light on what system parameters effectively set the value of P.

  15. Potential Cislunar and Interplanetary Proving Ground Excursion Trajectory Concepts

    Science.gov (United States)

    McGuire, Melissa L.; Strange, Nathan J.; Burke, Laura M.; MacDonald, Mark A.; McElrath, Timothy P.; Landau, Damon F.; Lantoine, Gregory; Hack, Kurt J.; Lopez, Pedro

    2016-01-01

    NASA has been investigating potential translunar excursion concepts to take place in the 2020s that would be used to test and demonstrate long duration life support and other systems needed for eventual Mars missions in the 2030s. These potential trajectory concepts could be conducted in the proving ground, a region of cislunar and near-Earth interplanetary space where international space agencies could cooperate to develop the technologies needed for interplanetary spaceflight. Enabled by high power Solar Electric Propulsion (SEP) technologies, the excursion trajectory concepts studied are grouped into three classes of increasing distance from the Earth and increasing technical difficulty: the first class of excursion trajectory concepts would represent a 90-120 day round trip trajectory with abort to Earth options throughout the entire length, the second class would be a 180-210 day round trip trajectory with periods in which aborts would not be available, and the third would be a 300-400 day round trip trajectory without aborts for most of the length of the trip. This paper provides a top-level summary of the trajectory and mission design of representative example missions of these three classes of excursion trajectory concepts.

  16. The Excursion Set Theory of Halo Mass Functions, Halo Clustering, and Halo Growth

    Science.gov (United States)

    Zentner, Andrew R.

    I review the excursion set theory with particular attention toward applications to cold dark matter halo formation and growth, halo abundance, and halo clustering. After a brief introduction to notation and conventions, I begin by recounting the heuristic argument leading to the mass function of bound objects given by Press and Schechter. I then review the more formal derivation of the Press-Schechter halo mass function that makes use of excursion sets of the density field. The excursion set formalism is powerful and can be applied to numerous other problems. I review the excursion set formalism for describing both halo clustering and bias and the properties of void regions. As one of the most enduring legacies of the excursion set approach and one of its most common applications, I spend considerable time reviewing the excursion set theory of halo growth. This section of the review culminates with the description of two Monte Carlo methods for generating ensembles of halo mass accretion histories. In the last section, I emphasize that the standard excursion set approach is the result of several simplifying assumptions. Dropping these assumptions can lead to more faithful predictions and open excursion set theory to new applications. One such assumption is that the height of the barriers that define collapsed objects is a constant function of scale. I illustrate the implementation of the excursion set approach for barriers of arbitrary shape. One such application is the now well-known improvement of the excursion set mass function derived from the "moving" barrier for ellipsoidal collapse. I also emphasize that the statement that halo accretion histories are independent of halo environment in the excursion set approach is not a general prediction of the theory. It is a simplifying assumption. I review the method for constructing correlated random walks of the density field in the more general case. I construct a simple toy model to illustrate that excursion set

  17. Forsmark site investigation. Bedrock geology - overview and excursion guide

    Energy Technology Data Exchange (ETDEWEB)

    Stephens, Michael B. (Geological Survey of Sweden, Uppsala (Sweden))

    2010-09-15

    Bearing in mind the significance of the bedrock data from the ground surface for the geological 3D modelling work, SKB decided to present excursion guides that serve in the demonstration of the bedrock geology at the ground surface in both the Forsmark (this guide) and Laxemar-Simpevarp areas. An excursion guide is also available for the Olkiluoto area in south-western Finland, which has been selected for the construction of a repository for the disposal of highly radioactive, spent nuclear fuel in Finland. The current excursion guide presents the bedrock geology and describes in detail the character of the bedrock at ten representative outcrops or outcrop areas at the ground surface in the site investigation area at Forsmark. All localities are located within or immediately adjacent to the proposed repository volume selected by SKB

  18. Oskarshamn site investigation. Bedrock geology - overview and excursion guide

    Energy Technology Data Exchange (ETDEWEB)

    Wahlgren, Carl-Henric (Geological Survey of Sweden, Uppsala (Sweden))

    2010-09-15

    Bearing in mind the significance of the bedrock data from the ground surface for the geological 3D modelling work, SKB decided to present excursion guides that serve in the demonstration of the bedrock geology at the ground surface in both the Forsmark and Laxemar-Simpevarp (this guide) areas. An excursion guide is also available for the Olkiluoto area in south-western Finland, which has been selected for the construction of a repository for the disposal of highly radioactive, spent nuclear fuel. The current excursion guide presents the bedrock geology and describes in detail the character of the bedrock at eight representative outcrops or outcrop areas at the ground surface in the site investigation area at Laxemar-Simpevarp and at one locality north of this area, i.e. at a total of nine localities

  19. Oskarshamn site investigation. Bedrock geology - overview and excursion guide

    International Nuclear Information System (INIS)

    Wahlgren, Carl-Henric

    2010-09-01

    Bearing in mind the significance of the bedrock data from the ground surface for the geological 3D modelling work, SKB decided to present excursion guides that serve in the demonstration of the bedrock geology at the ground surface in both the Forsmark and Laxemar-Simpevarp (this guide) areas. An excursion guide is also available for the Olkiluoto area in south-western Finland, which has been selected for the construction of a repository for the disposal of highly radioactive, spent nuclear fuel. The current excursion guide presents the bedrock geology and describes in detail the character of the bedrock at eight representative outcrops or outcrop areas at the ground surface in the site investigation area at Laxemar-Simpevarp and at one locality north of this area, i.e. at a total of nine localities

  20. Forsmark site investigation. Bedrock geology - overview and excursion guide

    International Nuclear Information System (INIS)

    Stephens, Michael B.

    2010-09-01

    Bearing in mind the significance of the bedrock data from the ground surface for the geological 3D modelling work, SKB decided to present excursion guides that serve in the demonstration of the bedrock geology at the ground surface in both the Forsmark (this guide) and Laxemar-Simpevarp areas. An excursion guide is also available for the Olkiluoto area in south-western Finland, which has been selected for the construction of a repository for the disposal of highly radioactive, spent nuclear fuel in Finland. The current excursion guide presents the bedrock geology and describes in detail the character of the bedrock at ten representative outcrops or outcrop areas at the ground surface in the site investigation area at Forsmark. All localities are located within or immediately adjacent to the proposed repository volume selected by SKB

  1. Diaphragmatic excursion: does it predict successful weaning from mechanical ventilation?

    International Nuclear Information System (INIS)

    Hayat, A.; Khalil, A.

    2017-01-01

    To measure the diaphragmatic excursion and its outcome on weani ng from mechanical ventilation. Study Design: Cross-sectional comparative study. Place and Duration of Study: Medical Intensive Care Unit (ICU), Military Hospital (MH), Rawalpindi, Pakistan, from January to December 2014. Methodology: Diaphragmatic excursion (DE) in cm was measured through ultrasound by marking liver and spleen displacement in patients who fulfilled the criteria of removal from ventilatory support. The patients were followed up for 48 hours and classified according to the outcome as successful weaning and weaning failure. Results: Out of 100 cases, 76 patients had a successful weaning while 24 had a failed weaning outcome. At a diaphragmatic excursion of 1.2 cm and more, out of 67 cases, 60 had a successful weaning (89.55%) while 7 cases (10.45%) had a weaning failure. At an excursion of less than 1. 2 cm, 17 out of 33 cases (51.5%) had successful weaning while 16 (48.48%) had weaning failure. At this cut off point (1.2 cm), the sensitivity and specificity for successful weaning were 78.95% and 70.83%, respectively. The positive and negative likelihood ratio (LR) for these values being 2.70 and 0.29, respectively. The positive predictive value was 82.35% and negative predictive value 60.00%. Conclusion: Ultrasonographic measurement of diaphragmatic excursion is a good method for predicting weaning outcome from mechanical ventilation. (author)

  2. Power Excursion Accident Analysis of Research Water Reactor

    International Nuclear Information System (INIS)

    Khaled, S.M.; Doaa, G.M.

    2009-01-01

    A three-dimensional neutronic code POWEX-K has been developed, and it has been coupled with the sub-channel thermal-hydraulic core analysis code SV based on the Single Mass Velocity Model. This forms the integrated neutronic/thermal hydraulics code system POWEX-K/SV for the accident analysis. The Training and Research Reactors at Budapest University of Technology and Economics (BME-Reactor) has been taken as a reference reactor. The cross-section generation procedure based on WIMS. The code uses an implicit difference approach for both the diffusion equations and thermal-hydraulics modules, with reactivity feedback effects due to coolant and fuel temperatures. The code system was applied to analyzing power excursion accidents initiated by ramp reactivity insertion of 1.2 $. The results show that the reactor is inherently safe in case of such accidents i.e. no core melt is expected even if the safety rods do not fall into the core

  3. 49 CFR 38.177 - Ferries, excursion boats and other vessels. [Reserved

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Ferries, excursion boats and other vessels... DISABILITIES ACT (ADA) ACCESSIBILITY SPECIFICATIONS FOR TRANSPORTATION VEHICLES Other Vehicles and Systems § 38.177 Ferries, excursion boats and other vessels. [Reserved] ...

  4. Correlation between glycemic excursion by CGMS and diabetic retinopathy among Type 2 diabetes mellitus

    International Nuclear Information System (INIS)

    Pu Li; Ji Ning; Zhu Wei

    2011-01-01

    Objective: To investigate correlation between glycemic excursion by CGMS and diabetic retinopathy among type 2 diabetes mellitus. Methods: Used continuous glucose monitoring system (CGMS) to monitoring glycemic excursion within a day of twenty four patients with type 2 diabetes mellitus, and inspect fundus photography, correlation was analyzed. Results: Glycemic excursion might reveal the risk for diabetic retinopathy better than HbA1c does. Conclusion: Diabetic retinopathy may correlate with glycemic excursion. (authors)

  5. Pressure modulation algorithm to separate cerebral hemodynamic signals from extracerebral artifacts.

    Science.gov (United States)

    Baker, Wesley B; Parthasarathy, Ashwin B; Ko, Tiffany S; Busch, David R; Abramson, Kenneth; Tzeng, Shih-Yu; Mesquita, Rickson C; Durduran, Turgut; Greenberg, Joel H; Kung, David K; Yodh, Arjun G

    2015-07-01

    We introduce and validate a pressure measurement paradigm that reduces extracerebral contamination from superficial tissues in optical monitoring of cerebral blood flow with diffuse correlation spectroscopy (DCS). The scheme determines subject-specific contributions of extracerebral and cerebral tissues to the DCS signal by utilizing probe pressure modulation to induce variations in extracerebral blood flow. For analysis, the head is modeled as a two-layer medium and is probed with long and short source-detector separations. Then a combination of pressure modulation and a modified Beer-Lambert law for flow enables experimenters to linearly relate differential DCS signals to cerebral and extracerebral blood flow variation without a priori anatomical information. We demonstrate the algorithm's ability to isolate cerebral blood flow during a finger-tapping task and during graded scalp ischemia in healthy adults. Finally, we adapt the pressure modulation algorithm to ameliorate extracerebral contamination in monitoring of cerebral blood oxygenation and blood volume by near-infrared spectroscopy.

  6. ORNITHOLOGICAL EXCURSIONS IN MURMANSK: GEOINFORMATION ASPECT

    Directory of Open Access Journals (Sweden)

    M. N. Kharlamova

    2014-01-01

    Full Text Available The method to use efficiently GIS-technologies in arranging the field practice of students on ornithology has been proposed. The ornithological excursions were performed in surroundings of the City of Murmansk in the conditions of weakly urbanized landscape. Using the facilities of freely distributed cartographic «SAS-Planet» software a simple GIS was formed in its environment where to the data on bird nest location with their description, the information about the route nodal points, water body crossing, stay places and others were put down. The mentioned data were obtained as a result of preliminary field research with the aid of satellite navigator including accumulating and summing up the information for a number of previous similar investigations. As a result, a final route in the current year was developed using which during the field practice the ornithological excursions were arranged.

  7. Pressure-modulation dynamic attenuated-total-reflectance (ATR) FT-IR spectroscopy

    Science.gov (United States)

    Marcott, C.; Story, G. M.; Noda, I.; Bibby, A.; Manning, C. J.

    1998-06-01

    A single-reflectance attenuated-total-reflectance (ATR) accessory with a diamond internal-reflection element was modified by the addition of a piezoelectric transducer. Initial dynamic pressure-modulation experiments have been performed in the sample compartment of a step-scanning FT-IR spectrometer. A sinusoidal pressure modulation applied to samples of isotactic polypropylene and linear low density polyethylene resulted in dynamic responses which appear to be similar to those observed in previous dynamic 2D IR experiments. Preliminary pressure-modulation dynamic ATR results are also reported for a styrene-butadiene-styrene triblock copolymer. The new method has the advantages that a much wider variety of sample types and geometries can be studied and less sample preparation is required. Dynamic 2D IR experiments carried out by ATR no longer require thin films of large area and sufficient strength to withstand the dynamic strain applied by a rheometer. The ability to obtain dynamic IR spectroscopic information from a wider variety of sample types and thicknesses would greatly expand the amount of useful information that could be extracted from normally complicated, highly overlapped IR spectra.

  8. Pressure Effects Analysis of National Ignition Facility Capacitor Module Events

    International Nuclear Information System (INIS)

    Brereton, S; Ma, C; Newton, M; Pastrnak, J; Price, D; Prokosch, D

    1999-01-01

    Capacitors and power conditioning systems required for the National Ignition Facility (NIF) have experienced several catastrophic failures during prototype demonstration. These events generally resulted in explosion, generating a dramatic fireball and energetic shrapnel, and thus may present a threat to the walls of the capacitor bay that houses the capacitor modules. The purpose of this paper is to evaluate the ability of the capacitor bay walls to withstand the overpressure generated by the aforementioned events. Two calculations are described in this paper. The first one was used to estimate the energy release during a fireball event and the second one was used to estimate the pressure in a capacitor module during a capacitor explosion event. Both results were then used to estimate the subsequent overpressure in the capacitor bay where these events occurred. The analysis showed that the expected capacitor bay overpressure was less than the pressure tolerance of the walls. To understand the risk of the above events in NIF, capacitor module failure probabilities were also calculated. This paper concludes with estimates of the probability of single module failure and multi-module failures based on the number of catastrophic failures in the prototype demonstration facility

  9. Tongue Pressure Modulation during Swallowing: Water versus Nectar-Thick Liquids

    Science.gov (United States)

    Steele, Catriona M.; Bailey, Gemma L.; Molfenter, Sonja M.

    2010-01-01

    Purpose: Evidence of tongue-palate pressure modulation during swallowing between thin and nectar-thick liquids stimuli has been equivocal. This mirrors a lack of clear evidence in the literature of tongue and hyoid movement modulation between nectar-thick and thin liquid swallows. In the current investigation, the authors sought to confirm whether…

  10. Age and Structure of the Laschamp Geomagnetic Excursion

    Science.gov (United States)

    Scaillet, S.; Laj, C.; Kissel, C.; Guillou, H.; Singer, B. S.

    2004-12-01

    The age of the Laschamp geomagnetic excursion has been recently re-investigated using unspiked K/Ar and Ar/Ar techniques (Guillou et al., Session V01, this conference). The new age determination of 40.4 +/- 2.0 ka (2 sigma) is more precise than those previously reported in the literature and agrees precisely with that deduced from the GLOPIS-75 sedimentary paleointensity stack calibrated against the GISP2 ice core chronology. Two of the North Atlantic cores used in GLOPIS-75 (MD95-2034 and PS2644-5) yield rather detailed transitional VGP paths. In the two cases the paths show large similarities, with the VGP initially descending along mid-western Pacific, then returning to normal polarities with a large clockwise loop over Africa and Europe. Differences in the highest southern latitudes reached by the VGP can be explained assuming more different degrees of smearing of the paleomagnetic record due to differences in sedimentation rate in the two cores. In the most detailed record, MD95-2034 , two smaller loops are present preceding the main excursion. In the two cores, the excursion is characterized by a significant drop in intensity. The reversal paths observed for the Laschamp event are very close in position to those reported for the Icelandic Basin Event (IBE) from sites in the North Atlantic and the South China Sea (Laj et al., this conference) but differ in the sense of looping: while a clockwise loop is observed here, a counterclockwise loop is observed for the IBE. Despite this difference, the similarity of the transitional records tends to suggest that a similar, relatively simple, geometry has dominated the two excursions and therefore that similar dynamo mechanisms have prevailed during the reversal process.

  11. Global characteristics of geomagnetic excursions as seen in global empirical models and a numerical geodynamo simulation

    Science.gov (United States)

    Korte, M. C.; Wardinski, I.; Brown, M. C.

    2016-12-01

    Paleomagnetic results from sediments and lava flows provide observational evidence of numerous geomagnetic excursions throughout Earth's history. Two new spherical harmonic geomagnetic field models covering 50-30 ka, including the Laschamp ( 41ka) and Mono Lake ( 32-35 ka) excursions allow us to characterize the global behaviour of these events, both at Earth's surface and the core-mantle boundary. We investigate the evolution of dipole and large-scale non-dipole power throughout the duration of the model and the morphology of the large-scale radial field at the core-mantle boundary. The models suggest clear differences in both the decrease in axial dipole strength and dipole tilt between the two excursions and unlike the previously published model by Leonhardt et al. (2009), they suggest some increase of non-dipole power during the early and late stages of the Laschamp excursion. Global characteristics from the models can be directly compared with results from numerical simulations. We do so for several excursions generated by a numerical simulation driven by purely compositional convection, which appears Earth-like in terms of excursion and reversal occurrence frequency. Excursions from this simulation show differing characteristics, including differences in spectral power evolution. Some cases show similarities to the Laschamp and Mono Lake excursions in the spherical harmonic models. In particular they all indicate that excursions are mainly governed by the axial dipole term and equatorial dipole terms play a minor role.

  12. Evaluation of tricuspid annular plane systolic excursion measured with cardiac MRI in children with tetralogy of Fallot.

    Science.gov (United States)

    Soslow, Jonathan H; Usoro, Emem; Wang, Li; Parra, David A

    2016-04-01

    Aneurysmal dilation of the right ventricular outflow tract complicates assessment of right ventricular function in patients with repaired tetralogy of Fallot. Tricuspid annular plane systolic excursion is commonly used to estimate ejection fraction. We hypothesised that tricuspid annular plane systolic excursion measured by cardiac MRI approximates global and segmental right ventricular function, specifically right ventricular sinus ejection fraction, in children with repaired tetralogy of Fallot. Tricuspid annular plane systolic excursion was measured retrospectively on cardiac MRIs in 54 patients with repaired tetralogy of Fallot. Values were compared with right ventricular global, sinus, and infundibular ejection fractions. Tricuspid annular plane systolic excursion was indexed to body surface area, converted into a fractional value, and converted into published paediatric Z-scores. Tricuspid annular plane systolic excursion measurements had good agreement between observers. Right ventricular ejection fraction did not correlate with the absolute or indexed tricuspid annular plane systolic excursion and correlated weakly with fractional tricuspid annular plane systolic excursion (r=0.41 and p=0.002). Segmental right ventricular function did not appreciably improve correlation with any of the tricuspid annular plane systolic excursion measures. Paediatric Z-scores were unable to differentiate patients with normal and abnormal right ventricular function. Tricuspid annular plane systolic excursion measured by cardiac MRI correlates poorly with global and segmental right ventricular ejection fraction in children with repaired tetralogy of Fallot. Tricuspid annular plane systolic excursion is an unreliable approximation of right ventricular function in this patient population.

  13. Electrical Pressurization Concept for the Orion MPCV European Service Module Propulsion System

    Science.gov (United States)

    Meiss, Jan-Hendrik; Weber, Jorg; Ierardo, Nicola; Quinn, Frank D.; Paisley, Jonathan

    2015-01-01

    The paper presents the design of the pressurization system of the European Service Module (ESM) of the Orion Multi-Purpose Crew Vehicle (MPCV). Being part of the propulsion subsystem, an electrical pressurization concept is implemented to condition propellants according to the engine needs via a bang-bang regulation system. Separate pressurization for the oxidizer and the fuel tank permits mixture ratio adjustments and prevents vapor mixing of the two hypergolic propellants during nominal operation. In case of loss of pressurization capability of a single side, the system can be converted into a common pressurization system. The regulation concept is based on evaluation of a set of tank pressure sensors and according activation of regulation valves, based on a single-failure tolerant weighting of three pressure signals. While regulation is performed on ESM level, commanding of regulation parameters as well as failure detection, isolation and recovery is performed from within the Crew Module, developed by Lockheed Martin Space System Company. The overall design and development maturity presented is post Preliminary Design Review (PDR) and reflects the current status of the MPCV ESM pressurization system.

  14. Use of hydrostatic pressure for modulation of protein chemical modification and enzymatic selectivity.

    Science.gov (United States)

    Makarov, Alexey A; Helmy, Roy; Joyce, Leo; Reibarkh, Mikhail; Maust, Mathew; Ren, Sumei; Mergelsberg, Ingrid; Welch, Christopher J

    2016-05-11

    Using hydrostatic pressure to induce protein conformational changes can be a powerful tool for altering the availability of protein reactive sites and for changing the selectivity of enzymatic reactions. Using a pressure apparatus, it has been demonstrated that hydrostatic pressure can be used to modulate the reactivity of lysine residues of the protein ubiquitin with a water-soluble amine-specific homobifunctional coupling agent. Fewer reactive lysine residues were observed when the reaction was carried out under elevated pressure of 3 kbar, consistent with a pressure-induced conformational change of ubiquitin that results in fewer exposed lysine residues. Additionally, modulation of the stereoselectivity of an enzymatic transamination reaction was observed at elevated hydrostatic pressure. In one case, the minor diasteromeric product formed at atmospheric pressure became the major product at elevated pressure. Such pressure-induced alterations of protein reactivity may provide an important new tool for enzymatic reactions and the chemical modification of proteins.

  15. Estimates of fission yields in nuclear criticality excursions

    International Nuclear Information System (INIS)

    Choi, J.S.; Thompson, J.W.; Reed, R.

    1995-06-01

    There is a need for computer simulation of hypothetical criticality excursions involving significant quantities of fissionable materials, especially in fissile aqueous system. The need arises due to the requirements for the emergency planning of facilities where the fissionable materials are handled, processed, or stored; and the regulatory requirements associated with facility operation or conversion. It is proposed here that a data base of fission yeilds for critical experiments and known accidents (both aqueous and solid) should be generated by using existing or new computer codes. The success in compiling this data base would provide useful source-terms for criticality excursions, realistic estimates of emergency-response boundary, as well as a replacement for the ''rule-of-thumb'' or ''bounding'' method. 10 refs

  16. Geology and prospecting in the Carpatians conference excursion guide

    Directory of Open Access Journals (Sweden)

    Jacko Stanislav

    2000-06-01

    Full Text Available We would like to welcome you to the excursions finalizing the Geology and prospecting in the Carpathians Conference, Her¾any –2000. The aim of the excursions is to provide you an overview of these Western Carpathian lithostructural units – and their mineralization respectively, research progress of which has been (at that time closely connected with personal investigation enthusiasm of our Professors - the founders of our Faculty. The current state of geological development knowledge of principal structural units of the Western Carpathians is outlined in papers included in special issue of Mineralia Slovaca magazine you have received at the begining of the Conference. For this reason the content of this Excursion quide is exclusively concentrated to description of routes localities. Broader geological relationships of particular outcrops is possible to find in attached Geological map of the Slovak Republic 1:100 000. The organizers of the excursions gratefully acknowledge the efforts of all colleagues who contributed to this quide. We also like to express our thanks for the financial support to Slovak VEGA grant Agency (Grant No:1/7389/2 and to the following organizations: Association of Metallurgy, Minig Industry and Geology of Slovak Republic, Slovak Geological Society, Management of TU Košice, SAPTU Foundation of TU Košice, Geological Survey of the Slovak Republic Betox JSC. Košice, SMW JSC. Jelšava, Uranpress Ltd. Spišská Nová Ves, TESCO Košice, ŽELBA-Siderite JSC. Nižná Slaná and ŽELBA –JSC. Spišská Nová Ves.

  17. Clericalization of the Russian Excursion Tourism

    Directory of Open Access Journals (Sweden)

    Boris Rodoman

    2014-05-01

    Full Text Available In the modern Russia almost every secular excursion is starting to resemble a religious pilgrimage, while reducing itself to a visit to Orthodox monasteries and temples. A lot of stories are told about saints and their actions, an unconcealed religious propaganda is carried on, and the history of the country is presented in a cleric-monarchical manner.

  18. Bounded excursion stable gravastars and black holes

    Energy Technology Data Exchange (ETDEWEB)

    Rocha, P [Instituto de Fisica, Universidade Federal Fluminense, Avenida Litoranea, s/n, Boa Viagem 24210-340, Niteroi, RJ (Brazil); Miguelote, A Y; Chan, R [Coordenacao de Astronomia e Astrofisica, Observatorio Nacional, Rua General Jose Cristino, 77, Sao Cristovao 20921-400, Rio de Janeiro, RJ (Brazil); Da Silva, M F; Wang, Anzhong [Departamento de Fisica Teorica, Instituto de Fisica, Universidade do Estado do Rio de Janeiro, Rua Sao Francisco Xavier 524, Maracana 20550-900, Rio de Janeiro-RJ (Brazil); Santos, N O, E-mail: pedrosennarocha@gmail.com, E-mail: yasuda@on.br, E-mail: chan@on.br, E-mail: mfasnic@gmail.com, E-mail: N.O.Santos@qmul.ac.uk, E-mail: anzhong_wang@baylor.edu [LERMA/CNRS-FRE 2460, Universite Pierre et Marie Curie, ERGA, Boite 142, 4 Place Jussieu, 75005 Paris Cedex 05 (France)

    2008-06-15

    Dynamical models of prototype gravastars were constructed in order to study their stability. The models are the Visser-Wiltshire three-layer gravastars, in which an infinitely thin spherical shell of stiff fluid divides the whole spacetime into two regions, where the internal region is de Sitter, and the external one is Schwarzschild. It is found that in some cases the models represent the 'bounded excursion' stable gravastars, where the thin shell is oscillating between two finite radii, while in other cases they collapse until the formation of black holes occurs. In the phase space, the region for the 'bounded excursion' gravastars is very small in comparison to that of black holes, but not empty. Therefore, although the possibility of the existence of gravastars cannot be excluded from such dynamical models, our results indicate that, even if gravastars do indeed exist, that does not exclude the possibility of the existence of black holes.

  19. Volcanic records of the Laschamp geomagnetic excursion from Mt Ruapehu, New Zealand

    Science.gov (United States)

    Ingham, E.; Turner, G. M.; Conway, C. E.; Heslop, D.; Roberts, A. P.; Leonard, G.; Townsend, D.; Calvert, A.

    2017-08-01

    We present palaeodirectional records of the Laschamp geomagnetic excursion from lavas on Mt Ruapehu, New Zealand. Fourteen lava flows on the northwestern and southern flanks of Mt Ruapehu, with 40Ar/39Ar weighted mean plateau ages that range from 46.3 ± 2.0 to 39.9 ± 1.4 ka, were studied. The youngest and older flows carry a normal polarity magnetization; however, six flows, dated between 46.3 ± 2.0 and 42.7 ± 1.8 ka, record excursional directions. Three of these flows record southerly palaeomagnetic declinations and negative inclinations that agree well with a published Laschamp record from the Auckland Volcanic Field (AVF). Together, the AVF and Mt Ruapehu lavas currently represent the only volcanic records of the Laschamp excursion outside the Chaîne des Puys region, France. Thus, they make an important contribution to the global set of Laschamp excursion records. Virtual geomagnetic pole (VGP) groups for the New Zealand and French records early in the excursion are compatible with a dipole-dominated field that rotated to an equatorial orientation while simultaneously decaying in strength. In contrast, younger excursional flows from France and New Zealand yield separate VGP groups, which suggest either that the field had a nondipolar morphology in this later phase, or that the VGP groups were not synchronous. 40Ar/39Ar ages for the Mt Ruapehu record are on average slightly older than published northern hemisphere ages and from the relative palaeointensity minimum in the GLOPIS sedimentary stack. Although few individual ages differ significantly at the 2σ level, the spread suggests an overall excursion duration that is longer than the currently accepted 1500 years. This age spread may result from excess Ar in magmas at the time of the eruption biasing the results to slightly older ages, or from non-synchronous excursional field behaviour at near-antipodal locations, or, possibly, a precursory phase prior to the main excursion.

  20. HMSRP Hawaiian Monk Seal Shark Predation Mitigation Fishing Excursions

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Fishing excursion information, including summary tables of: Fishing/culling efforts, including date, islets, latitude/longitude, fishing method, soak times, culled...

  1. Experimental Investigation of Pressure Drop and Pressure Distribution Along a Heated Channel in Subcooled Flow Boiling

    International Nuclear Information System (INIS)

    Aharon, Y.; Hochbaum, I.; Shai, I.

    2002-01-01

    The state of knowledge relating to pressure drop in subcooled boiling region is very unsatisfactory. That pressure drop is an important factor in considering the design of nuclear reactors because of the possibility of flow excursion during a two phase flow in the channels. In operational systems with multiple flow channels, an increase in pressure drop in one flow channel, can cause the flow to be diverted to other channels. A burnout can occur in the unstable channel

  2. Experimental investigation of a spiral-wound pressure-retarded osmosis membrane module for osmotic power generation.

    Science.gov (United States)

    Kim, Yu Chang; Kim, Young; Oh, Dongwook; Lee, Kong Hoon

    2013-03-19

    Pressure-retarded osmosis (PRO) uses a semipermeable membrane to produce renewable energy from salinity-gradient energy. A spiral-wound (SW) design is one module configuration of the PRO membrane. The SW PRO membrane module has two different flow paths, axial and spiral, and two different spacers, net and tricot, for draw- and feed-solution streams, respectively. This study used an experimental approach to investigate the relationship between two interacting flow streams in a prototype SW PRO membrane module, and the adverse impact of a tricot fabric spacer (as a feed spacer) on the PRO performance, including water flux and power density. The presence of the tricot spacer inside the membrane envelope caused a pressure drop due to flow resistance and reduced osmotic water permeation due to the shadow effect. The dilution of the draw solution by water permeation resulted in the reduction of the osmotic pressure difference along a pressure vessel. For a 0.6 M NaCl solution and tap water, the water flux and corresponding maximum power density were 3.7 L m(-2)h(-1) and 1.0 W/m(2) respectively at a hydraulic pressure difference of 9.8 bar. The thickness and porosity of the tricot spacer should be optimized to achieve high SW PRO module performance.

  3. Maximum Acceptable Vibrato Excursion as a Function of Vibrato Rate in Musicians and Non-musicians

    DEFF Research Database (Denmark)

    Vatti, Marianna; Santurette, Sébastien; Pontoppidan, Niels H.

    2014-01-01

    and, in most listeners, exhibited a peak at medium vibrato rates (5–7 Hz). Large across-subject variability was observed, and no significant effect of musical experience was found. Overall, most listeners were not solely sensitive to the vibrato excursion and there was a listener-dependent rate...... for which larger vibrato excursions were favored. The observed interaction between maximum excursion thresholds and vibrato rate may be due to the listeners’ judgments relying on cues provided by the rate of frequency changes (RFC) rather than excursion per se. Further studies are needed to evaluate......Human vibrato is mainly characterized by two parameters: vibrato extent and vibrato rate. These parameters have been found to exhibit an interaction both in physical recordings of singers’ voices and in listener’s preference ratings. This study was concerned with the way in which the maximum...

  4. UF{sub 6} pressure excursions during cylinder heating

    Energy Technology Data Exchange (ETDEWEB)

    Brown, P.G. [Martin Marietta Energy Systems, Inc., Paducah, KY (United States)

    1991-12-31

    As liquid UF{sub 6} inside a cylinder changes from a liquid to a solid, it forms a porous solid which occupies approximately the same volume as that of the liquid before cooling. Simultaneously as the liquid cools, UF{sub 6} vapor in the cylinder ullage above the liquid desublimes on the upper region of the inner cylinder wall. This solid is a dense, glass-like material which can accumulate to a significant thickness. The thickness of the solid coating on the upper cylinder wall and directly behind the cylinder valve area will vary depending on the conditions during the cooling stage. The amount of time lapsed between UF{sub 6} solidification and UF{sub 6} liquefaction can also affect the UF{sub 6} coating. This is due to the daily ambient heat cycle causing the coating to sublime from the cylinder wall to cooler areas, thus decreasing the thickness. Structural weakening of the dense UF{sub 6} layer also occurs due to cylinder transport vibration and thermal expansion. During cylinder heating, the UF{sub 6} nearest the cylinder wall will liquefy first. As the solid coating behind the cylinder valve begins to liquefy, it results in increased pressure depending upon the available volume for expansion. At the Paducah Gaseous Diffusion Plant (PGDP) during the liquefaction of the UF{sub 6} in cylinders in the UF{sub 6} feed and sampling autoclaves, this pressure increase has resulted in the activation of the systems rupture discs which are rated at 100 pounds per square inch differential.

  5. Sedimentary and Volcanic Records of the Laschamp and Mono Lake Excursions from Australia and New Zealand

    Science.gov (United States)

    Ingham, E. M.; Roberts, A. P.; Turner, G. M.; Heslop, D.; Ronge, T.; Conway, C.; Leonard, G.; Townsend, D.; Tiedemann, R.; Lamy, F.; Calvert, A. T.

    2014-12-01

    Geomagnetic excursions are short-lived deviations of the geomagnetic field from the normal range of secular variation. Despite significant advances in geomagnetic excursion research over the past 20 years, fundamental questions remain concerning the typical duration and global morphology of excursional geomagnetic fields. To answer such questions, more high-resolution, chronologically well-constrained excursion records are required, particularly from the Southern Hemisphere. We present preliminary paleomagnetic records of the Laschamp (~41 ka) and Mono Lake (~35 ka) excursions from three marine sediment cores from the Bounty Trough, New Zealand margin, and complementary volcanic records of the Laschamp excursion from lavas of Mt Ruapehu, New Zealand. Relatively high sedimentation rates of 12 - 26 cm/kyr in the Bounty Trough during glacial periods allow identification of excursional field behavior at each of the studied core locations. Each core displays one or two excursional events, with rapid directional swings between stable normal polarity and reversed excursional directions, each associated with coincident relative paleointensity minima. These anomalous paleomagnetic directions are interpreted to represent the Laschamp and Mono Lake excursions, based on a combination of tephrochronology, radiocarbon dating, and cyclostratigraphy (defined from core-scanning X-ray fluorescence and magnetic susceptibility records). Beside these records, we present results from fourteen lava flows, on Mt Ruapehu, for which 40Ar-39Ar dating indicates ages of between 39 and 45 ka. The step heating 40Ar-39Ar experiments produced particularly flat age plateaus, with corresponding 2 s.d. errors mostly approaching 1 kyr. The youngest and oldest flows carry normal polarity magnetization, however six flows, dated between 41 and 43 ka, display transitional field characteristics. Three of these flows display a declination swing of around 180o, which coincides with a previously published

  6. Evaluation of Tricuspid Annular Plane Systolic Excursion Measured with Cardiac Magnetic Resonance Imaging in Pediatric Patients with Tetralogy of Fallot

    Science.gov (United States)

    Soslow, Jonathan H.; Usoro, Emem; Wang, Li; Parra, David A.

    2015-01-01

    Background Aneurysmal dilation of the right ventricular outflow tract complicates assessment of right ventricular function in patients with repaired tetralogy of Fallot. Tricuspid annular plane systolic excursion is commonly used to estimate ejection fraction. We hypothesized that tricuspid annular plane systolic excursion measured by cardiac magnetic resonance imaging approximates global and segmental right ventricular function, specifically right ventricular sinus ejection fraction, in pediatric patients with repaired tetralogy of Fallot. Methods Tricuspid annular plane systolic excursion was measured retrospectively on cardiac magnetic resonance images in 54 patients with repaired tetralogy of Fallot. Values were compared with right ventricular global, sinus, and infundibular ejection fractions. Tricuspid annular plane systolic excursion was: 1) indexed to body surface area, 2) converted into a fractional value, and 3) converted into published pediatric Z-scores. Results Tricuspid annular plane systolic excursion measurements had good agreement between observers. Right ventricular ejection fraction did not correlate with the absolute or indexed tricuspid annular plane systolic excursion and correlated weakly with fractional tricuspid annular plane systolic excursion (r=0.41 and p=0.002). Segmental right ventricular function did not appreciably improve correlation with any of the tricuspid annular plane systolic excursion measures. Pediatric Z-scores were unable to differentiate patients with normal and abnormal right ventricular function. Conclusions Tricuspid annular plane systolic excursion measured on cardiac magnetic resonance imaging correlates poorly with global and segmental right ventricular ejection fraction in pediatric patients with repaired tetralogy of Fallot. Tricuspid annular plane systolic excursion is an unreliable approximation of right ventricular function in this patient population. PMID:26279488

  7. Beam tests of 'SPACAL' type modules for a high pressure gas calorimeter

    International Nuclear Information System (INIS)

    Konstantinov, V.F.; Krasnokutskij, R.N.; Shuvalov, R.S.; Solodkov, A.A.; Starchenko, E.A.; Sushkov, V.V.; Zajtsev, A.M.; Dzhelyadin, R.I.; Kopikov, S.V.; Solov'yanov, O.V.

    1993-01-01

    High-pressure gas modules with cylindrical ionization chambers for a Very Forward Calorimeter are constructed and tested in the IHEP U-70 electron beam. The amplifiers are used in a remote mode (3 m long cables). The module performance at small angles is tested in the energy range of 10-30 GeV using different gas mixtures like Ar + CH 4 , Ar + CF 4 and pure CF 4 at the pressure of 20-40 Atm. The best value of energy resolution equal to 18% is reached at the angle of 5.7 deg for 30 GeV electrons. The design is found to be adequate for future use in ATLAS/LHC. 24 refs., 10 figs

  8. Pressure modulation algorithm to separate cerebral hemodynamic signals from extracerebral artifacts

    OpenAIRE

    Baker, Wesley B.; Parthasarathy, Ashwin B.; Ko, Tiffany S.; Busch, David R.; Abramson, Kenneth; Tzeng, Shih-Yu; Mesquita, Rickson C.; Durduran, Turgut; Greenberg, Joel H.; Kung, David K.; Yodh, Arjun G.

    2015-01-01

    We introduce and validate a pressure measurement paradigm that reduces extracerebral contamination from superficial tissues in optical monitoring of cerebral blood flow with diffuse correlation spectroscopy (DCS). The scheme determines subject-specific contributions of extracerebral and cerebral tissues to the DCS signal by utilizing probe pressure modulation to induce variations in extracerebral blood flow. For analysis, the head is modeled as a two-layer medium and is probed with long and s...

  9. A long-term geomagnetic excursion from Plio-Pleistocene sediments in Java

    Science.gov (United States)

    Hyodo, Masayuki; Sunata, Wahyu; Susanto, Eko E.

    1992-06-01

    Duplicate records of a geomagnetic excursion at two sites separated by 200 km in Java, Indonesia, are reported. The existence of a large-scale wing of declination between the Olduvai and Jaramillo event is revealed. The field directions in reverse polarity show a gradual clockwise swing to almost west-pointing directions, followed by a rapid return to south-pointing directions. At both sites, the declinations have maximum deflection more than 70 deg from the axial dipole field direction, and the inclinations remain low during the swing. An upward-pointing eccentric radial dipole model rather than a downward-pointing one seems plausible to explain the geomagnetic behavior during the excursion.

  10. The range of excursion of flexor tendons in Zone V: a comparison of active vs passive flexion mobilisation regimes.

    LENUS (Irish Health Repository)

    Panchal, J

    1997-10-01

    A number of early postoperative mobilisation regimes have been developed in an attempt to increase tendon excursion and gliding and thereby reduce formation of adhesions following repair of flexor tendons. Early active flexion mobilisation regimes are becoming more popular, and have replaced early passive flexion regimes in many centres. The aim of the present study was: (a) to determine the range of excursion of flexor tendons in Zone V, and (b) to compare the excursion ranges between active (Belfast) and passive (modified Duran) flexion mobilisation regimes postoperatively. This was done (a) in two cadavers, and (b) in two patients intraoperatively, and postoperatively at 10 days, 3 weeks and 6 weeks. With passive flexion, the mean tendon excursion in Zone V in cadavers was 1 mm for flexor digitorum superficialis (FDS), flexor digitorum profundus (FDP) and flexor pollicis longus (FPL) tendons respectively. With simulated active flexion, the mean tendon excursion was 14 mm, 10 mm and 11 mm respectively. The mean tendon excursion in clinical cases intraoperatively following passive flexion was 2 mm for FDS, FDP and FPL respectively; following simulated active flexion it was 10 mm, 11 mm and 11 mm for FDS, FDP and FPL respectively. On the tenth day following repair, the mean excursions of FDS, FDP and FPL were 1 mm, 4 mm and 4 mm on passive flexion as compared to 3 mm, 10 mm and 12 mm on active flexion respectively. Three weeks postoperatively, the mean excursions of FDS, FDP and FPL tendons were 1 mm, 2 mm and 1 mm on passive flexion as compared to 5 mm, 15 mm on active flexion respectively. Six weeks postoperatively, the mean excursions of FDS, FDP and FPL tendons were 9 mm, 7 mm and 4 mm on passive flexion as compared to 12 mm, 33 mm and 20 mm on active flexion respectively. These results demonstrate an increased excursion of repaired flexor tendons in Zone V following an active flexion mobilisation regime as compared to a passive flexion mobilisation regime.

  11. Rapid directional changes associated with a 6.5 kyr-long Blake geomagnetic excursion at the Blake-Bahama Outer Ridge

    DEFF Research Database (Denmark)

    Bourne, Mark; McNiocaill, Conall; Thomas, Alexander

    2012-01-01

    Geomagnetic excursions are recognized as intrinsic features of the Earth's magnetic field. High-resolution records of field behaviour, captured in marine sedimentary cores, present an opportunity to determine the temporal and geometric character of the field during geomagnetic excursions...... and provide constraints on the mechanisms producing field variability. We present here the highest resolution record yet published of the Blake geomagnetic excursion (similar to 125 ka) measured in three cores from Ocean Drilling Program (ODP) Site 1062 on the Blake-Bahama Outer Ridge. The Blake excursion has...... a controversial structure and timing but these cores have a sufficiently high sedimentation rate (similar to 10 cm ka(-1)) to allow detailed reconstruction of the field behaviour at this site during the excursion. Palaeomagnetic measurements of the cores reveal rapid transitions (

  12. Cerium anomaly across the mid-Tournaisian carbon isotope excursion (TICE)

    Science.gov (United States)

    Jiang, G.; Morales, D. C.; Maharjan, D. K.

    2015-12-01

    The Early Mississippian (ca. 359-345 Ma) represents one of the most important greenhouse-icehouse climate transitions in Earth history. Closely associated with this critical transition is a prominent positive carbon isotope excursion (δ13C ≥ +5‰) that has been documented from numerous stratigraphic successions across the globe. This δ13C excursion, informally referred to as the TICE (mid-Tournaisian carbon isotope excursion) event, has been interpreted as resulting from enhanced organic carbon burial, with anticipated outcomes including the lowering of atmospheric CO2 and global cooling, the growth of continental ice sheets and sea-level fall, and the increase of ocean oxygenation and ocean redox changes. The casual relationship between these events has been addressed from various perspectives but not yet clearly demonstrated. To document the potential redox change associated with the perturbation of the carbon cycle, we have analyzed rare earth elements (REE) and trace elements across the TICE in two sections across a shallow-to-deep water transect in the southern Great Basin (Utah and Nevada), USA. In both sections, the REE data show a significant positive cerium (Ce) anomaly (Ce/Ce* = Ce/(0.5La+0.5Pr)). Prior to the positive δ13C shift, most Ce/Ce* values are around 0.3 (between 0.2 and 0.4). Across the δ13C peak, Ce/Ce* values increase up to 0.87, followed by a decrease back to 0.2~0.3 after the δ13C excursion (Figure 1). The positive Ce anomaly is best interpreted as recording expansion of oxygen minimum zone and anoxia resulted from increased primary production. This is consistent with a significant increase of nitrogen isotopes (δ15N) across the δ13C peak. Integration of the carbon, nitrogen, and REE data demonstrates a responsive earth systems change linked to the perturbation of the Early Mississippian carbon cycle.

  13. Visual evidence of the Sterno-Etrussia geomagnetic excursion (~2700 BP)?

    Science.gov (United States)

    Raspopov, O. M.; Dergachev, V. A.; Goos'kova, E. G.; Morner, N.-A.

    2003-04-01

    In the Bible's Old Testament Book of Ezekiel there is a description of the Ezekiel's vision of "a great cloud with brightness round about it" to the north of the observation site. The event described in the Bible occurred in 593 BC, i.e., approximately 2600 years ago. Ezekiel was at that time approximately 100 km south of Babylon (latitude ~ 32 N, longitude ~ 45 E). Auroral specialists interpret the Ezekiel's vision as observation of coronal auroral displays at low latitudes. However, to support this hypothesis, it is necessary to understand the physical mechanism responsible for generation of these forms of auroras at low latitudes. Analysis of palaeo- and archaeomagnetic data, including our data on magnetic properties of sediments of the Barents and White Seas and the literature data, has shown that about 2700 BP, i.e., in Ezekiel's time, development of a geomagnetic "Sterno-Etrussia" excursion took place. The duration of the excursion during which the northern geomagnetic pole wandered to the Southern Hemisphere was no more than 200-300 years. Manifestations of this excursion were found in 16 regions of the Eurasian continent and adjacent seas and also in the North and South America. By plotting the path along which the northern geomagnetic pole wandered to the southern latitudes during this excursion on the basis of palaeomagnetic data, we have found that it wandered in the longitude sector plus or minus 30 degrees, and about 2700 BP the northern geomagnetic pole was at the longitude close to the Babylon longitude, where Ezekiel had his vision. Thus, at that time Babylon was at high geomagnetic latitudes where regular coronal auroral displays occur. Records of observation of the unusual brightness of the sky in the V-VI centuries BC can also be found in Greek chronicles. This indicates that the Ezekiel's vision was not the only observation of auroras at low latitudes during the period considered here. This work was supported by INTAS, Grant 97-31008 and PFBR

  14. Study of thermal and hydraulic phenomena accompanying a rapid power excursion on a heating channel

    International Nuclear Information System (INIS)

    Nyer, M.

    1989-01-01

    This document provides a study of power excursion phenomena and is divided into five sections. In the first chapter a summary of the principal research conducted world-wide on the thermal and hydrodynamic aspects of power excursions actualized either in the reactors or on installations outside of the pile is provided. In a second chapter, on the basis of the bibliographic study conducted previously, the characteristics and performance that an installation capable of correctly simulating a power excursion are indicated and the experimental device designed and developed is described with emphasis on the measurement methods used. In the third chapter the principal experimental results obtained, as well as their physical interpretation, are given. In the fourth chapter a simplified theoretical model that makes it possible to determine the manner of variation of the phenomena observed during our experiments is proposed, and in the fifth chapter what our study has added to the understanding of the phenomena that arise during a power excursion and the direction that the research should be continued is discussed. 38 refs., 69 figs

  15. Foot reflexology can increase vagal modulation, decrease sympathetic modulation, and lower blood pressure in healthy subjects and patients with coronary artery disease.

    Science.gov (United States)

    Lu, Wan-An; Chen, Gau-Yang; Kuo, Cheng-Deng

    2011-01-01

    Complementary and alternative medicine (CAM) has long been used by people to postpone the aging process and to reverse disease progression. Reflexology is a CAM method that involves massage to reflex areas in the feet and hands. This study investigated the effect of foot reflexology (FR) on the autonomic nervous modulation in patients with coronary artery disease (CAD) by using heart rate variability analysis. Seventeen people with angiographically patent coronary arteries and 20 patients with CAD scheduled for coronary artery bypass graft surgery were recruited as the control and CAD groups, respectively. The normalized high-frequency power (nHFP) was used as the index of vagal modulation and the normalized very low-frequency power (nVLFP) as the index of vagal withdrawal and renin-angiotensin modulation. In both control and CAD groups, the nHFP was increased significantly whereas the nVLFP was decreased significantly 30 and 60 minutes after FR, as compared with those before FR. The systolic, diastolic, mean arterial, and pulse pressures were significantly decreased after FR in both groups of participants. In the CAD group, the percentage change in heart rate 30 and 60 minutes after FR was smaller than that in the control, and the percentage change in nVLFP 60 minutes after FR was smaller than that in the control. In conclusion, a higher vagal modulation, lower sympathetic modulation, and lower blood pressure can be observed following 60 minutes of FR in both controls and CAD patients. The magnitude of change in the autonomic nervous modulation in CAD patients was slightly smaller than that in the controls. FR may be used as an efficient adjunct to the therapeutic regimen to increase the vagal modulation and decrease blood pressure in both healthy people and CAD patients.

  16. Fuel-steel mixing and radial mesh effects in power excursion simulations

    International Nuclear Information System (INIS)

    Chen, X.-N.; Rineiski, A.; Gabrielli, F.; Andriolo, L.; Vezzoni, B.; Li, R.; Maschek, W.; Kiefhaber, E.

    2016-01-01

    Highlights: • Fuel-steel mixing and radial mesh effects are significant on power excursion. • The earliest power peak is reduced and retarded by these two effects. • Unprotected loss of coolant transients in ESFR core are calculated. - Abstract: This paper deals with SIMMER-III once-through simulations of the earliest power excursion initiated by an unprotected loss of flow (ULOF) in the Working Horse design of the European Sodium Cooled Fast Reactor (ESFR). Since the sodium void effect is strictly positive in this core and dominant in the transient, a power excursion is initiated by sodium boiling in the ULOF case. Two major effects, namely (1) reactivity effects due to fuel-steel mixing after melting and (2) the radial mesh size, which were not considered originally in SIMMER simulations for ESFR, are studied. The first effect concerns the reactivity difference between the heterogeneous fuel/clad/wrapper configuration and the homogeneous mixture of steel and fuel. The full core homogenization (due to melting) effect is −2 $, though a smaller effect takes place in case of partial core melting. The second effect is due to the SIMMER sub-assembly (SA) coarse mesh treatment, where a simultaneous sodium boiling onset in all SAs belonging to one ring leads to an overestimated reactivity ramp. For investigating the influence of fuel/steel mixing effects, a lumped “homogenization” reactivity feedback has been introduced, being proportional to the molten steel mass. For improving the coarse mesh treatment, we employ finer radial meshes to take the subchannel effects into account, where the side and interior channels have different coolant velocities and temperatures. The simulation results show that these two effects have significant impacts on the earliest power excursion after the sodium boiling.

  17. FELIX - a computer code for simulation of criticality excursions in liquid fissile solutions

    International Nuclear Information System (INIS)

    Gmal, B.; Weber, J.

    1989-01-01

    Knowledge of characteristic parameters like evolved power fission yield during an accidental excursion is of essential importance to estimate possible radiological consequences and resulting safety hazards. The computer code 'FELIX' simulates excursion characteristics of aqueous critical assemblies: Starting out from given initial conditions the space-dependent neutron kinetic equations are solved in one-dimensional geometry. Power, fission yield, reactivity and temperature are calculated as a function of time. Reactivity-feedback includes density effects and radiolytic gas voids. Results from calculations are compared with CRAC-experiments. (orig.)

  18. Comparison of clinical utility between diaphragm excursion and thickening change using ultrasonography to predict extubation success

    Science.gov (United States)

    Yoo, Jung-Wan; Lee, Seung Jun; Lee, Jong Deog; Kim, Ho Cheol

    2018-01-01

    Background/Aims Both diaphragmatic excursion and change in muscle thickening are measured using ultrasonography (US) to assess diaphragm function and mechanical ventilation weaning outcomes. However, which parameter can better predict successful extubation remains to be determined. The aim of this study was to compare the clinical utility of these two diaphragmatic parameters to predict extubation success. Methods This study included patients subjected to extubation trial in the medical or surgical intensive care unit of a university-affiliated hospital from May 2015 through February 2016. Diaphragm excursion and percent of thickening change (Δtdi%) were measured using US within 24 hours before extubation. Results Sixty patients were included, and 78.3% (47/60) of these patients were successfully extubated, whereas 21.7% (13/60) were not. The median degree of excursion was greater in patients with extubation success than in those with extubation failure (1.65 cm vs. 0.8 cm, p success had a greater Δtdi% than those with extubation failure (42.1% vs. 22.5%, p = 0.03). The areas under the receiver operating curve for excursion and Δtdi% were 0.836 (95% confidence interval [CI], 0.717 to 0.919) and 0.698 (95% CI, 0.566 to 0.810), respectively (p = 0.017). Conclusions Diaphragm excursion seems more accurate than a change in the diaphragm thickness to predict extubation success. PMID:29050461

  19. Excursions out-of-lane versus standard deviation of lateral position as outcome measure of the on-the-road driving test.

    Science.gov (United States)

    Verster, Joris C; Roth, Thomas

    2014-07-01

    The traditional outcome measure of the Dutch on-the-road driving test is the standard deviation of lateral position (SDLP), the weaving of the car. This paper explores whether excursions out-of-lane are a suitable additional outcome measure to index driving impairment. A literature search was conducted to search for driving tests that used both SDLP and excursions out-of-lane as outcome measures. The analyses were limited to studies examining hypnotic drugs because several of these drugs have been shown to produce next-morning sedation. Standard deviation of lateral position was more sensitive in demonstrating driving impairment. In fact, solely relying on excursions out-of-lane as outcome measure incorrectly classifies approximately half of impaired drives as unimpaired. The frequency of excursions out-of-lane is determined by the mean lateral position within the right traffic lane. Defining driving impairment as having a ΔSDLP > 2.4 cm, half of the impaired driving tests (51.2%, 43/84) failed to produce excursions out-of-lane. Alternatively, 20.9% of driving tests with ΔSDLP < 2.4 cm (27/129) had at least one excursion out-of-lane. Excursions out-of-lane are neither a suitable measure to demonstrate driving impairment nor is this measure sufficiently sensitive to differentiate adequately between differences in magnitude of driving impairment. Copyright © 2014 John Wiley & Sons, Ltd.

  20. The effect of different unstable footwear constructions on centre of pressure motion during standing.

    Science.gov (United States)

    Plom, W; Strike, S C; Taylor, M J D

    2014-06-01

    The aim of this study was to test the effect different unstable footwear constructions have on centre of pressure motion when standing. Sixteen young female volunteers were tested in five conditions, three unstable footwear (Reebok Easy-Tone, FitFlop and Skechers Shape-Ups), a standard shoe and barefoot in a randomised order. Double and single leg balance on a force plate was assessed via centre of pressure excursions and displacements in each condition. For double leg and single leg standing centre of pressure excursions in the anterior-posterior direction were significantly increased wearing Skechers Shape-Ups compared to barefoot and the standard shoe. For the Reebok Easy Tone during single leg standing excursions in the anterior-posterior direction were significantly greater compared to the barefoot condition. Cumulative displacement of the centre of pressure in medial-lateral direction increased significantly during single leg standing when wearing Skechers Shape-Ups compared to barefoot and standard shoe as well as for Reebok Easy Tone vs. barefoot. It would appear from these quiet standing results that the manner of the construction of instability shoes effects the CoP movement which is associated with induced instability. Greater CoP excursion occurred in the A-P direction while the cumulative displacements were greater in the M-L direction for those shoes with the rounded sole and soft foam and those with airpods. The shoe construction with altered density foam did not induce any change in the CoP movement, during quite standing, which tends to suggest that it is not effective at inducing balance. Not all instability shoes are effective in altering the overall instability of the wearer. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Postmeal exercise blunts postprandial glucose excursions in people on metformin monotherapy.

    Science.gov (United States)

    Erickson, Melissa L; Little, Jonathan P; Gay, Jennifer L; McCully, Kevin K; Jenkins, Nathan T

    2017-08-01

    Metformin is used clinically to reduce fasting glucose with minimal effects on postprandial glucose. Postmeal exercise reduces postprandial glucose and may offer additional glucose-lowering benefit beyond that of metformin alone, yet controversy exists surrounding exercise and metformin interactions. It is currently unknown how postmeal exercise and metformin monotherapy in combination will affect postprandial glucose. Thus, we examined the independent and combined effects of postmeal exercise and metformin monotherapy on postprandial glucose. A randomized crossover design was used to assess the influence of postmeal exercise on postprandial glucose excursions in 10 people treated with metformin monotherapy (57 ± 10 yr, HbA 1C  = 6.3 ± 0.6%). Each participant completed the following four conditions: sedentary and postmeal exercise (5 × 10-min bouts of treadmill walking at 60% V̇o 2max ) with metformin and sedentary and postmeal exercise without metformin. Peak postprandial glucose within a 2-h time window and 2-h total area under the curve was assessed after a standardized breakfast meal, using continuous glucose monitoring. Postmeal exercise significantly blunted 2-h peak ( P = 0.001) and 2-h area under the curve ( P = 0.006), with the lowest peak postprandial glucose excursion observed with postmeal exercise and metformin combined ( P exercise: 9.7 ± 2.3, washout/sedentary: 13.3 ± 3.2, washout/exercise: 11.1 ± 3.4 mmol/l). Postmeal exercise and metformin in combination resulted in the lowest peak postprandial glucose excursion compared with either treatment modality alone. Exercise timed to the postprandial phase may be important for optimizing glucose control during metformin monotherapy. NEW & NOTEWORTHY The interactive effects of metformin and exercise on key physiological outcomes remain an area of controversy. Findings from this study show that the combination of metformin monotherapy and moderate-intensity postmeal exercise led to

  2. Conditional Probabilities in the Excursion Set Theory. Generic Barriers and non-Gaussian Initial Conditions

    CERN Document Server

    De Simone, Andrea; Riotto, Antonio

    2011-01-01

    The excursion set theory, where density perturbations evolve stochastically with the smoothing scale, provides a method for computing the dark matter halo mass function. The computation of the mass function is mapped into the so-called first-passage time problem in the presence of a moving barrier. The excursion set theory is also a powerful formalism to study other properties of dark matter halos such as halo bias, accretion rate, formation time, merging rate and the formation history of halos. This is achieved by computing conditional probabilities with non-trivial initial conditions, and the conditional two-barrier first-crossing rate. In this paper we use the recently-developed path integral formulation of the excursion set theory to calculate analytically these conditional probabilities in the presence of a generic moving barrier, including the one describing the ellipsoidal collapse, and for both Gaussian and non-Gaussian initial conditions. The non-Markovianity of the random walks induced by non-Gaussi...

  3. Preliminary feasibility analysis of a pressure modulator radiometer for remote sensing of tropospheric constituents

    Science.gov (United States)

    Orr, H. D., III; Rarig, P. L.

    1981-01-01

    A pressure modulator radiometer operated in a nadir viewing mode from the top of a midlatitude summer model of the atmosphere was theoretically studied for monitoring the mean volumetric mixing ratio of carbon monoxide in the troposphere. The mechanical characteristics of the instrument on the Nimbus 7 stratospheric and mesospheric sounder experiment are assumed and CO is assumed to be the only infrared active constituent. A line by line radiative transfer computer program is used to simulate the upwelling radiation reaching the top of the atmosphere. The performance of the instrument is examined as a function of the mean pressure in and the length of the instrument gas correlation cell. Instrument sensitivity is described in terms of signal to noise ratio for a 10 percent change in CO mixing ratio. Sensitivity to mixing ratio changes is also studied. It is concluded that tropospheric monitoring requires a pressure modulator drive having a larger swept volume and producing higher compression ratios at higher mean cell pressures than the Nimbus 7 design.

  4. On the joint distribution of excursion duration and amplitude of a narrow-band Gaussian process

    DEFF Research Database (Denmark)

    Ghane, Mahdi; Gao, Zhen; Blanke, Mogens

    2018-01-01

    of amplitude and period are limited to excursion through a mean-level or to describe the asymptotic behavior of high level excursions. This paper extends the knowledge by presenting a theoretical derivation of probability of wave exceedance amplitude and duration, for a narrow-band Gaussian process......The probability density of crest amplitude and of duration of exceeding a given level are used in many theoretical and practical problems in engineering. The joint density is essential for design of constructions that are subjected to waves and wind. The presently available joint distributions...... distribution, as expected, and that the marginal distribution of excursion duration works both for asymptotic and non-asymptotic cases. The suggested model is found to be a good replacement for the empirical distributions that are widely used. Results from simulations of narrow-band Gaussian processes, real...

  5. All-Optical Frequency Modulated High Pressure MEMS Sensor for Remote and Distributed Sensing

    DEFF Research Database (Denmark)

    Reck, Kasper; Thomsen, Erik Vilain; Hansen, Ole

    2011-01-01

    We present the design, fabrication and characterization of a new all-optical frequency modulated pressure sensor. Using the tangential strain in a circular membrane, a waveguide with an integrated nanoscale Bragg grating is strained longitudinally proportional to the applied pressure causing...... a shift in the Bragg wavelength. The simple and robust design combined with the small chip area of 1 × 1.8 mm2 makes the sensor ideally suited for remote and distributed sensing in harsh environments and where miniaturized sensors are required. The sensor is designed for high pressure applications up...

  6. Partial-depth modulation study of anions and neutrals in low pressure silane plasmas

    International Nuclear Information System (INIS)

    Cozurteille, C.; Dorier, J.L.; Hollenstein, C.; Sansonnens; Howling, A.A.

    1995-10-01

    Partial-depth modulation of the rf power in a capacitive discharge is used to investigate the relative importance of negative ions and neutral radicals for particle formation in low power, low pressure silane plasmas. For less than 85% modulation depth, anions are trapped indefinitely in the plasma and particle formation ensues, whereas the polymerised neutral flux magnitudes and dynamics are independent of the modulation depth and the powder formation. These observations suggest that negative ions could be the particle precursors in plasma conditions where powder appears many seconds after plasma ignition. Microwave interferometry and mass spectrometry were combined to infer an anion density of ≅7.10 9 cm -3 which is approximately twice the free electron density in these modulated plasmas. (author) 6 figs., tabs., refs

  7. Magnetosheath excursion and the relevant transport process at the magnetopause

    Directory of Open Access Journals (Sweden)

    C. L. Cai

    2009-08-01

    Full Text Available A large-amplitude excursion of the magnetosheath (MS in quiet solar wind conditions on 17 March 2004 was recorded simultaneously by the Cluster and TC-1 spacecraft. During this period, the IMF Bz was entirely northward. The coherence between the bow shock motion and magnetopause (MP motion is revealed and the excursion velocities of the bow shock motion are analyzed. In addition, the relevant plasma transport phenomenon in the form of flux fluctuations below the ion gyrofrequency at the MP is exposed and is interpreted as manifestation of the drift instability. Correlated observations on charge accumulation and electrostatic potential perturbation are recorded by electron measurements in high energy regime, and also the eventual cross-field vortex motion in the nonlinear stage and the consequential mass exchange are exhibited. The present investigation gives some new insight into the MS plasma transport mechanism across the subsolar MP region in quiet solar wind conditions during a period of northward IMF.

  8. Glucose and triglyceride excursions following a standardized meal in individuals with diabetes: ELSA-Brasil study.

    Science.gov (United States)

    Riboldi, Bárbara P; Luft, Vivian C; de Castilhos, Cristina D; de Cardoso, Letícia O; Schmidt, Maria I; Barreto, Sandhi M; de Sander, Maria F; Alvim, Sheila M; Duncan, Bruce B

    2015-02-13

    To assess glucose and triglyceride excursions 2 hours after the ingestion of a standardized meal and their associations with clinical characteristics and cardiovascular complications in individuals with diabetes. Blood samples of 898 subjects with diabetes were collected at fasting and 2 hours after a meal containing 455 kcal, 14 g of saturated fat and 47 g of carbohydrates. Self-reported morbidity, socio-demographic characteristics and clinical measures were obtained by interview and exams performed at the baseline visit of the ELSA-Brasil cohort study. Median (interquartile range, IQR) for fasting glucose was 150.5 (123-198) mg/dL and for fasting triglycerides 140 (103-199) mg/dL. The median excursion for glucose was 45 (15-76) mg/dL and for triglycerides 26 (11-45) mg/dL. In multiple linear regression, a greater glucose excursion was associated with higher glycated hemoglobin (10.7, 95% CI 9.1-12.3 mg/dL), duration of diabetes (4.5; 2.6-6.4 mg/dL, per 5 year increase), insulin use (44.4; 31.7-57.1 mg/dL), and age (6.1; 2.5-9.6 mg/dL, per 10 year increase); and with lower body mass index (-5.6; -8.4- -2.8 mg/dL, per 5 kg/m2 increase). In adjusted logistic regression models, a greater glucose excursion was marginally associated with the presence of cardiovascular comorbidities (coronary heart disease, myocardial infarction and angina) in those with obesity. A greater postprandial glycemic response to a small meal was positively associated with indicators of a decreased capacity for insulin secretion and negatively associated with obesity. No pattern of response was observed with a greater postprandial triglyceride excursion.

  9. Improved stability and performance from sigma-delta modulators using 1-bit vector quantization

    DEFF Research Database (Denmark)

    Risbo, Lars

    1993-01-01

    A novel class of sigma-delta modulators is presented. The usual scalar 1-b quantizer in a sigma-delta modulator is replaced by a 1-b vector quantizer with a N-dimensional input state-vector from the linear feedback filter. Generally, the vector quantizer changes the nonlinear dynamics...... of the modulator, and a proper choice of vector quantizer can improve both system stability and coding performance. It is shown how to construct the vector quantizer in order to limit the excursions in state-space. The proposed method is demonstrated graphically for a simple second-order modulator...

  10. The Hirnantian δ13C Positive Excursion in the Nabiullino Section (South Urals)

    Science.gov (United States)

    Yakupov, R. R.; Mavrinskaya, T. M.; Smoleva, I. V.

    2018-02-01

    The upper Sandbian, Katian, and Hirnantian complexes of conodonts in the upper Ordovician section of the western slope of the Southern Urals near the village of Nabiullino were studied. The δ13C positive excursion with a maximum of 3.3‰ associated with the global Hirnantian isotopic event, HICE, was fixed for the first time. This excursion shows the beginning of the Hirnantian stage in the terrigenous-carbonate section of the upper Ordovician in the Southern Urals. It coincides with the first occurrence of the Hirnantian conodont species of Gamachignathus ensifer and the conodonts of shallow-water biophacies, Aphelognathus-Ozarkodina, reflecting the global glacio-eustatic event.

  11. Study of the thermal and hydraulic phenomena occurring during power excursion on a heated test section

    International Nuclear Information System (INIS)

    Nyer, M.

    1969-01-01

    The thermal and hydrodynamic phenomena occurring during a power excursion were studied in an out-of-pile loop with a water cooled channel at low pressure (1 to 4 atm. abs. ). Circular and rectangular test sections with electrically heated walls of two different thermal diffusivity materials(aluminium and stainless steel) were used. The rectangular test sections were 600 mm long, 35 mm wide and had a 2, 9 mm gap; they simulate two half plates of the M.T.R. fuel element. Natural or forced convection are possible in the test section; the water height above it can be varied from 2.8 to 8 meters and the maximum allowed pressure at its outlet is 4 atm. abs.The heating source is a series of lead batteries which is able to generate, for short periods of time, 85 volts and 25000 amperes; linear, square or exponential power rise versus time can be realized. A 14 channels tape recorder (0-10 000 Hz bandwidth; is used for the measurements of temperature (8/100 mm diameter thermocouple), pressure ('Statham' pressure transducers) and void fraction (X rays). More than 500 tests have been carried out. The influence of the initial water temperature, flow rate, pressure, water height on the water ejections, pressure variations and void fraction in the test section were studied. Tests with energies up to 3000 W/cm in 50 milliseconds were attempted. The energy above which the instabilities appear was determined. An interpretation of the observed phenomena and a simplified theoretical model are presented [fr

  12. Comparison of longitudinal excursion of a nerve-phantom model using quantitative ultrasound imaging and motion analysis system methods: A convergent validity study.

    Science.gov (United States)

    Paquette, Philippe; El Khamlichi, Youssef; Lamontagne, Martin; Higgins, Johanne; Gagnon, Dany H

    2017-08-01

    Quantitative ultrasound imaging is gaining popularity in research and clinical settings to measure the neuromechanical properties of the peripheral nerves such as their capability to glide in response to body segment movement. Increasing evidence suggests that impaired median nerve longitudinal excursion is associated with carpal tunnel syndrome. To date, psychometric properties of longitudinal nerve excursion measurements using quantitative ultrasound imaging have not been extensively investigated. This study investigates the convergent validity of the longitudinal nerve excursion by comparing measures obtained using quantitative ultrasound imaging with those determined with a motion analysis system. A 38-cm long rigid nerve-phantom model was used to assess the longitudinal excursion in a laboratory environment. The nerve-phantom model, immersed in a 20-cm deep container filled with a gelatin-based solution, was moved 20 times using a linear forward and backward motion. Three light-emitting diodes were used to record nerve-phantom excursion with a motion analysis system, while a 5-cm linear transducer allowed simultaneous recording via ultrasound imaging. Both measurement techniques yielded excellent association ( r  = 0.99) and agreement (mean absolute difference between methods = 0.85 mm; mean relative difference between methods = 7.48 %). Small discrepancies were largely found when larger excursions (i.e. > 10 mm) were performed, revealing slight underestimation of the excursion by the ultrasound imaging analysis software. Quantitative ultrasound imaging is an accurate method to assess the longitudinal excursion of an in vitro nerve-phantom model and appears relevant for future research protocols investigating the neuromechanical properties of the peripheral nerves.

  13. Pressure Modulation of the Enzymatic Activity of Phospholipase A2, A Putative Membrane-Associated Pressure Sensor.

    Science.gov (United States)

    Suladze, Saba; Cinar, Suleyman; Sperlich, Benjamin; Winter, Roland

    2015-10-07

    Phospholipases A2 (PLA2) catalyze the hydrolysis reaction of sn-2 fatty acids of membrane phospholipids and are also involved in receptor signaling and transcriptional pathways. Here, we used pressure modulation of the PLA2 activity and of the membrane's physical-chemical properties to reveal new mechanistic information about the membrane association and subsequent enzymatic reaction of PLA2. Although the effect of high hydrostatic pressure (HHP) on aqueous soluble and integral membrane proteins has been investigated to some extent, its effect on enzymatic reactions operating at the water/lipid interface has not been explored, yet. This study focuses on the effect of HHP on the structure, membrane binding and enzymatic activity of membrane-associated bee venom PLA2, covering a pressure range up to 2 kbar. To this end, high-pressure Fourier-transform infrared and high-pressure stopped-flow fluorescence spectroscopies were applied. The results show that PLA2 binding to model biomembranes is not significantly affected by pressure and occurs in at least two kinetically distinct steps. Followed by fast initial membrane association, structural reorganization of α-helical segments of PLA2 takes place at the lipid water interface. FRET-based activity measurements reveal that pressure has a marked inhibitory effect on the lipid hydrolysis rate, which decreases by 75% upon compression up to 2 kbar. Lipid hydrolysis under extreme environmental conditions, such as those encountered in the deep sea where pressures up to the kbar-level are encountered, is hence markedly affected by HHP, rendering PLA2, next to being a primary osmosensor, a good candidate for a sensitive pressure sensor in vivo.

  14. Effects of numerical dissipation and unphysical excursions on scalar-mixing estimates in large-eddy simulations

    Science.gov (United States)

    Sharan, Nek; Matheou, Georgios; Dimotakis, Paul

    2017-11-01

    Artificial numerical dissipation decreases dispersive oscillations and can play a key role in mitigating unphysical scalar excursions in large eddy simulations (LES). Its influence on scalar mixing can be assessed through the resolved-scale scalar, Z , its probability density function (PDF), variance, spectra, and the budget of the horizontally averaged equation for Z2. LES of incompressible temporally evolving shear flow enabled us to study the influence of numerical dissipation on unphysical scalar excursions and mixing estimates. Flows with different mixing behavior, with both marching and non-marching scalar PDFs, are studied. Scalar fields for each flow are compared for different grid resolutions and numerical scalar-convection term schemes. As expected, increasing numerical dissipation enhances scalar mixing in the development stage of shear flow characterized by organized large-scale pairings with a non-marching PDF, but has little influence in the self-similar stage of flows with marching PDFs. Flow parameters and regimes sensitive to numerical dissipation help identify approaches to mitigate unphysical excursions while minimizing dissipation.

  15. Wavelength modulation diode laser absorption spectroscopy for high-pressure gas sensing

    Science.gov (United States)

    Sun, K.; Chao, X.; Sur, R.; Jeffries, J. B.; Hanson, R. K.

    2013-03-01

    A general model for 1 f-normalized wavelength modulation absorption spectroscopy with nf detection (i.e., WMS- nf) is presented that considers the performance of injection-current-tuned diode lasers and the reflective interference produced by other optical components on the line-of-sight (LOS) transmission intensity. This model explores the optimization of sensitive detection of optical absorption by species with structured spectra at elevated pressures. Predictions have been validated by comparison with measurements of the 1 f-normalized WMS- nf (for n = 2-6) lineshape of the R(11) transition in the 1st overtone band of CO near 2.3 μm at four different pressures ranging from 5 to 20 atm, all at room temperature. The CO mole fractions measured by 1 f-normalized WMS-2 f, 3 f, and 4 f techniques agree with calibrated mixtures within 2.0 %. At conditions where absorption features are significantly broadened and large modulation depths are required, uncertainties in the WMS background signals due to reflective interference in the optical path can produce significant error in gas mole fraction measurements by 1 f-normalized WMS-2 f. However, such potential errors can be greatly reduced by using the higher harmonics, i.e., 1 f-normalized WMS- nf with n > 2. In addition, less interference from pressure-broadened neighboring transitions has been observed for WMS with higher harmonics than for WMS-2 f.

  16. Free gracilis transfer for smile in children: the Massachusetts Eye and Ear Infirmary Experience in excursion and quality-of-life changes.

    Science.gov (United States)

    Hadlock, Tessa A; Malo, Juan S; Cheney, Mack L; Henstrom, Douglas K

    2011-01-01

    Free muscle transfer for facial reanimation has become the standard of care in recent decades and is now the cornerstone intervention for dynamic smile reanimation. We sought to quantify smile excursion and quality-of-life (QOL) changes in our pediatric free gracilis recipients following reanimation. We quantified gracilis muscle excursion in 17 pediatric patients undergoing 19 consecutive pediatric free gracilis transplantation operations, using our validated SMILE program, as an objective measure of functional outcome. These were compared against excursion measured the same way in a cohort of 17 adults with 19 free gracilis operations. In addition, we prospectively evaluated QOL outcomes in these children using the Facial Clinimetric Evaluation (FaCE) instrument. The mean gracilis excursion in our pediatric free gracilis recipients was 8.8 mm ± 5.0 mm, which matched adult results, but with fewer complete failures of less than 2-mm excursion, with 2 (11%) and 4 (21%), respectively. Quality-of-life measures indicated statistically significant improvements following dynamic smile reanimation (P = .01). Dynamic facial reanimation using free gracilis transfer in children has an acceptable success rate, yields improved commissure excursion, and improves QOL in the pediatric population. It should be considered first-line therapy for children with lack of a meaningful smile secondary to facial paralysis.

  17. Revealing the Microscopic Real-Space Excursion of a Laser-Driven Electron

    Directory of Open Access Journals (Sweden)

    Heiko G. Kurz

    2016-08-01

    Full Text Available High-order harmonic spectroscopy allows one to extract information on fundamental quantum processes, such as the exit time in the tunneling of an electron through a barrier with attosecond time resolution and molecular structure with angstrom spatial resolution. Here, we study the spatial motion of the electron during high-order harmonic generation in an in situ pump-probe measurement using high-density liquid water droplets as a target. We show that molecules adjacent to the emitting electron-ion pair can disrupt the electron’s trajectory when positioned within the range of the maximum electronic excursion distance. This allows us to use the parent ion and the neighboring molecules as boundaries for the electronic motion to measure the maximum electronic excursion distance during the high-order harmonic generation process. Our analysis of the process is relevant for optimizing high-harmonic yields in dense media.

  18. Perioperative optimal blood pressure as determined by ultrasound tagged near infrared spectroscopy and its association with postoperative acute kidney injury in cardiac surgery patients.

    Science.gov (United States)

    Hori, Daijiro; Hogue, Charles; Adachi, Hideo; Max, Laura; Price, Joel; Sciortino, Christopher; Zehr, Kenton; Conte, John; Cameron, Duke; Mandal, Kaushik

    2016-04-01

    Perioperative blood pressure management by targeting individualized optimal blood pressure, determined by cerebral blood flow autoregulation monitoring, may ensure sufficient renal perfusion. The purpose of this study was to evaluate changes in the optimal blood pressure for individual patients, determined during cardiopulmonary bypass (CPB) and during early postoperative period in intensive care unit (ICU). A secondary aim was to examine if excursions below optimal blood pressure in the ICU are associated with risk of cardiac surgery-associated acute kidney injury (CSA-AKI). One hundred and ten patients undergoing cardiac surgery had cerebral blood flow monitored with a novel technology using ultrasound tagged near infrared spectroscopy (UT-NIRS) during CPB and in the first 3 h after surgery in the ICU. The correlation flow index (CFx) was calculated as a moving, linear correlation coefficient between cerebral flow index measured using UT-NIRS and mean arterial pressure (MAP). Optimal blood pressure was defined as the MAP with the lowest CFx. Changes in optimal blood pressure in the perioperative period were observed and the association of blood pressure excursions (magnitude and duration) below the optimal blood pressure [area under the curve (AUC) blood pressure during early ICU stay and CPB was correlated (r = 0.46, P AUC blood pressure during CPB and in the ICU was correlated. Excursions below optimal blood pressure (AUC blood pressure management based on cerebral autoregulation monitoring during the perioperative period may help improve CSA-AKI-related outcomes. © The Author 2016. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

  19. Compact frequency-modulation Q-switched single-frequency fiber laser at 1083 nm

    International Nuclear Information System (INIS)

    Zhang, Yuanfei; Feng, Zhouming; Xu, Shanhui; Mo, Shupei; Yang, Changsheng; Li, Can; Gan, Jiulin; Chen, Dongdan; Yang, Zhongmin

    2015-01-01

    A compact frequency-modulation Q-switched single-frequency fiber laser is demonstrated at 1083 nm. The short linear resonant cavity consists of a 12 mm long homemade Yb 3+ -doped phosphate fiber and a pair of fiber Bragg gratings (FBGs) in which the Q-switching and the frequency excursion is achieved by a tensile-induced period modulation. Over 375 MHz frequency-tuning range is achieved with a modulation frequency varying from tens to hundreds of kilohertz. The highest peak power of the output pulse reaching 6.93 W at the repetition rate of 10 kHz is obtained. (paper)

  20. Virtual reality excursions with programs in C

    CERN Document Server

    Watkins, Christopher D

    1994-01-01

    Virtual Reality Excursions with Programs in C provides the history, theory, principles and an account of the milestones in the development of virtual reality technology.The book is organized into five chapters. The first chapter explores the applications in the vast field of virtual reality. The second chapter presents a brief history of the field and its founders. Chapter 3 discusses human perception and how it works. Some interesting notes and much of the hot debate in the field are covered in Chapter 4. The fifth chapter describes many of the complexities involved in implementing virtual en

  1. Study of the thermal and hydraulic phenomena occurring during power excursion on a heated test section; Etude des phenomenes thermiques et hydrauliques accompagnant une excursion rapide de puissance sur un canal chauffant

    Energy Technology Data Exchange (ETDEWEB)

    Nyer, M [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1969-07-01

    The thermal and hydrodynamic phenomena occurring during a power excursion were studied in an out-of-pile loop with a water cooled channel at low pressure (1 to 4 atm. abs. ). Circular and rectangular test sections with electrically heated walls of two different thermal diffusivity materials(aluminium and stainless steel) were used. The rectangular test sections were 600 mm long, 35 mm wide and had a 2, 9 mm gap; they simulate two half plates of the M.T.R. fuel element. Natural or forced convection are possible in the test section; the water height above it can be varied from 2.8 to 8 meters and the maximum allowed pressure at its outlet is 4 atm. abs.The heating source is a series of lead batteries which is able to generate, for short periods of time, 85 volts and 25000 amperes; linear, square or exponential power rise versus time can be realized. A 14 channels tape recorder (0-10 000 Hz bandwidth; is used for the measurements of temperature (8/100 mm diameter thermocouple), pressure ('Statham' pressure transducers) and void fraction (X rays). More than 500 tests have been carried out. The influence of the initial water temperature, flow rate, pressure, water height on the water ejections, pressure variations and void fraction in the test section were studied. Tests with energies up to 3000 W/cm in 50 milliseconds were attempted. The energy above which the instabilities appear was determined. An interpretation of the observed phenomena and a simplified theoretical model are presented. [French] Les phenomenes thermiques et hydrodynamiques qui apparaissent au cours d'une excursion de puissance ont ete etudies sur un canal refroidi par de l'eau a basse pression situe sur une installation hors pile. On a utilise des sections d'essais de geometrie cylindrique ou parallipedique dont les parois chauffees par effet Joule sont constituees de materiaux de diffusivite calorifique differente (aluminium et acier inoxydable). La section d'essais parallipedique a 600 mm de long

  2. Highway driving safety the day after using sleep medication: the direction of lapses and excursions out-of-lane in drowsy drivers.

    Science.gov (United States)

    Verster, Joris C; Mooren, Loes; Bervoets, Adriana C; Roth, Thomas

    2017-10-24

    The primary outcome measure of the on-road driving test is the Standard Deviation of Lateral Position. However, other outcome measures, such as lapses and excursions out-of-lane, also need to be considered as they may be related to crash risk. The aim of this study was to determine the direction of lapses and excursions out-of-lane (i.e. towards/into the adjacent traffic lane or towards/into the road shoulder). In total, data from 240 driving tests were re-analysed, and 628 lapses and 401 excursions out-of-lane were identified. The analyses revealed that lapses were made equally frequently over left (49.4%) and over right (43.3%). In contrast, excursions out-of-lane were almost exclusively directed over right into the (safer) road shoulder (97.3%). These findings suggest that drivers are unaware of having lapses, whereas excursions out-of-lane are events where the driver is aware of loss of vehicle control. © 2017 The Authors. Journal of Sleep Research published by John Wiley & Sons Ltd on behalf of European Sleep Research Society.

  3. Tricuspid annular plane systolic excursion and response to cardiac resynchronization therapy

    DEFF Research Database (Denmark)

    Kjaergaard, Jesper; Ghio, Stefano; St John Sutton, Martin

    2011-01-01

    The aims of this study were to evaluate tricuspid annular plane systolic excursion (TAPSE) as a predictor of left ventricular (LV) reverse remodeling and clinical benefit of cardiac synchronization therapy (CRT) and to evaluate the effect of CRT on TAPSE in patients with mildly symptomatic systol...

  4. Reduced Bearing Excursion After Mobile-Bearing Unicompartmental Knee Arthroplasty is Associated With Poor Functional Outcomes.

    Science.gov (United States)

    Wahal, Naman; Gaba, Sahil; Malhotra, Rajesh; Kumar, Vijay; Pegg, Elise C; Pandit, Hemant

    2018-02-01

    A small proportion of patients with mobile unicompartmental knee arthroplasty (UKA) report poor functional outcomes in spite of optimal component alignment on postoperative radiographs. The purpose of this study is to assess whether there is a correlation between functional outcome and knee kinematics. From a cohort of consecutive cases of 150 Oxford medial UKA, patients with fair/poor functional outcome at 1-year postsurgery (Oxford Knee Score [OKS] bearing position with knee flexion angle. Mean OKS in the fair/poor group was 29.9 and the mean OKS in the good/excellent group was 41.1. The tibial slope, time taken to complete the exercises, and patellar tendon angle trend over the flexion range were similar in both the groups; however, bearing position and the extent of bearing excursion differed significantly. The total bearing excursion in the OKS bearing was positioned 1.7 mm more posterior on the tibia in the OKS bearing excursion and positioning, are associated with worse functional outcomes after mobile UKA. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Numerically induced pressure excursions in two-phase-flow calculations. Final report

    International Nuclear Information System (INIS)

    Mahaffy, J.H.; Liles, D.R.

    1983-01-01

    Pressure spikes that cannot be traced to any physical origin sometimes are observed when standard Eulerian finite-difference methods are used to calculate two-phase-flow transients. This problem occurs with varying frequency in nuclear reactor safety codes such as RELAP, RETRAN, COBRA, and TRAC. These spikes usually result from numerical water packing or from interactions between spatial discretization and heat transfer

  6. Civil and Patriotic Education of Students by Means of Excursion Activities in Russia in the Second Half of XIX – Early XX Centuries

    Directory of Open Access Journals (Sweden)

    Nadezhda V. Tarasova

    2014-06-01

    Full Text Available The article is concerned with the problem of civil and patriotic education of students by means of voluntary activity, presents historical and educational analysis of excursion activities as one of the major forms of volunteer work of schoolchildren in Russia in the second half of the XIX – early XX centuries, determines its major goals and objectives. The paper, using archive data, attempts to consider excursion activity as one of the major forms of volunteer work, promoting patriotism development in rising generation. The opinions of innovative teachers of the examined period, who considered that excursions had great educational potential are characterized. The position of the Ministry of Education, concerning educational potential of excursions is examined.

  7. Cryogenic High Pressure Sensor Module

    Science.gov (United States)

    Chapman, John J. (Inventor); Shams, Qamar A. (Inventor); Powers, William T. (Inventor)

    1999-01-01

    A pressure sensor is provided for cryogenic, high pressure applications. A highly doped silicon piezoresistive pressure sensor is bonded to a silicon substrate in an absolute pressure sensing configuration. The absolute pressure sensor is bonded to an aluminum nitride substrate. Aluminum nitride has appropriate coefficient of thermal expansion for use with highly doped silicon at cryogenic temperatures. A group of sensors, either two sensors on two substrates or four sensors on a single substrate are packaged in a pressure vessel.

  8. A school excursion to a museum can promote physical activity in children by integrating movement into curricular activities

    DEFF Research Database (Denmark)

    Mygind, Lærke; Kryger, Tine; Sidenius, Gry

    2017-01-01

    Since children spend a large proportion of their time in institutional settings such as schools, health promotion researchers have identified this as an important setting to promote physical activity (PA). Apart from physical education, PA could be integrated into the school curriculum in other...... consisted of an excursion day to a museum. While an increase in light physical activity and reduction in the amount of sedentary time was observed, students did not spend more time in moderate to vigorous PA (MVPA) during the visit to the museum than on a regular school day. However, over the full excursion...... day, the students accumulated more MVPA. One school used active transportation to and from the museum, which contributed to significantly more MVPA compared to the other schools. An excursion to a museum significantly reduced sedentary time, but was in itself not sufficient to increase MVPA....

  9. A school excursion to a museum can promote physical activity in children by integrating movement into curricular activities

    DEFF Research Database (Denmark)

    Mygind, Lærke; Kryger, Tine B; Sidenius, Gry

    2018-01-01

    day, the students accumulated more MVPA. One school used active transportation to and from the museum, which contributed to significantly more MVPA compared to the other schools. An excursion to a museum significantly reduced sedentary time, but was in itself not sufficient to increase MVPA.......Since children spend a large proportion of their time in institutional settings such as schools, health promotion researchers have identified this as an important setting to promote physical activity (PA). Apart from physical education, PA could be integrated into the school curriculum in other...... consisted of an excursion day to a museum. While an increase in light physical activity and reduction in the amount of sedentary time was observed, students did not spend more time in moderate to vigorous PA (MVPA) during the visit to the museum than on a regular school day. However, over the full excursion...

  10. Mary Poppins and the Soviet Pilgrimage: P.L.Travers's Moscow Excursion (1934

    Directory of Open Access Journals (Sweden)

    John McNair

    2013-02-01

    Full Text Available Like the journey it chronicles, Moscow Excursion, P.L.Travers’s account of her 1932 visit to Russia, was in part inspired by the genre it effectively parodies: the ‘Soviet pilgrimage’ ‘truth about Russia’ narrative characteristic of the Stalin decades and exemplified (in the Australian context by Katharine Susannah Prichard’s The Real Russia, also published in 1934. The paper examines the ways in which Travers’s book is written against this genre to produce an avowedly ‘un-political’ record whose narrator rejects the restrictions of organized travel, and whose idiosyncratic and critical observations on Soviet reality contrast with the admiration of her more orthodox fellow-travellers for the usual showcase institutions on the official itinerary. At the same time, it is argued that in its blend of self-deprecating irony, whimsy and disillusioned idealism Moscow Excursion suggests parallels with Travers’s personal quest for ‘the truth’ and even with Mary Poppins, published only two months later.

  11. Duration of and decoupling between carbon isotope excursions during the end-Triassic mass extinction and Central Atlantic Magmatic Province emplacement

    Science.gov (United States)

    Yager, Joyce A.; West, A. Joshua; Corsetti, Frank A.; Berelson, William M.; Rollins, Nick E.; Rosas, Silvia; Bottjer, David J.

    2017-09-01

    Changes in δ13Ccarb and δ13Corg from marine strata occur globally in association with the end-Triassic mass extinction and the emplacement of the Central Atlantic Magmatic Province (CAMP) during the break up of Pangea. As is typical in deep time, the timing and duration of these isotopic excursions has remained elusive, hampering attempts to link carbon cycle perturbations to specific processes. Here, we report δ13Ccarb and δ13Corg from Late Triassic and Early Jurassic strata near Levanto, Peru, where intercalated dated ash beds permit temporal calibration of the carbon isotope record. Both δ13Ccarb and δ13Corg exhibit a broad positive excursion through the latest Triassic into the earliest Jurassic. The first order positive excursion in δ13Corg is interrupted by a negative shift noted in many sections around the world coincident with the extinction horizon. Our data indicate that the negative excursion lasts 85 ± 25 kyrs, longer than inferred by previous studies based on cyclostratigraphy. A 260 ± 80 kyr positive δ13Corg shift follows, during which the first Jurassic ammonites appear. The overall excursion culminates in a return to pre-perturbation carbon isotopic values over the next 1090 ± 70 kyrs. Via chronologic, isotopic, and biostratigraphic correlation to other successions, we find that δ13Ccarb and δ13Corg return to pre-perturbation values as CAMP volcanism ceases and in association with the recovery of pelagic and benthic biota. However, the initiation of the carbon isotope excursion at Levanto predates the well-dated CAMP sills from North America, indicating that CAMP may have started earlier than thought based on these exposures, or that the onset of carbon cycle perturbations was not related to CAMP.

  12. Report of the excursion Energy from Biomass to Germany, 26-28 November 1997

    International Nuclear Information System (INIS)

    Gigler, J.K.

    1997-12-01

    The aim of the title excursion was to provide participants with up-to-date information of different aspects with respect to the production of energy from biomass. Visits were paid to the main office and the research centre of 'Lurgi Umwelt' in Frankfurt am Main, the cogeneration installation 'Pflanzenoel-Blockheizkraftwerk' in Greussenheim, a local government organization, involved in the management of biomass projects, CARMEN ('Centrales Agrar Rohstoff Marketing und Entwicklungs-Netzwerk' or Central Agricultural Raw Material Marketing and Development Network) in Wuerzburg, the 22 MW biomass heating power plant 'Biomasse-Heizkraftwerk Sulzbach-Rosenberg' in Sulzbach-Rosenberg, and the research institute (in particular with respect to miscanthus) 'Bayerische Landesanstalt fuer Weinbau und Gartenbau' in Wuerzburg. Next to an evaluation of the excursion and an overview of the experiences of the participants background information from the visited sites is presented

  13. Eyelid reanimation with gold weight implant and tendon sling suspension: evaluation of excursion and velocity using the FACIAL CLIMA system.

    Science.gov (United States)

    Hontanilla, Bernardo; Marre, Diego

    2013-04-01

    This study aims to analyse the efficacy of static techniques, namely gold weight implant and tendon sling, in the reanimation of the paralytic eyelid. Upper eyelid rehabilitation in terms of excursion and blinking velocity is performed using the automatic motion capture system, FACIAL CLIMA. Seventy-four patients underwent a total of 101 procedures including 58 upper eyelid gold weight implants and 43 lower eyelid tendon suspension with 27 patients undergoing both procedures. The presence of lagophtalmos, eye dryness, corneal ulcer, epiphora and lower lid ptosis/ectropion was assessed preoperatively. The Wilcoxon signed-rank test was used to compare preoperative versus postoperative measurements of upper eyelid excursion and blinking velocity determined with FACIAL CLIMA. Significance was set at p CLIMA revealed significant improvement of eyelid excursion and velocity of blinking (p CLIMA system is a reliable method to quantify upper eyelid excursion and blinking velocity and to detect the exact position of the lower eyelid. Copyright © 2012 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

  14. Nonlinear intersubband absorption and refractive index changes in square and graded quantum well modulated by temperature and Hydrostatic pressure

    International Nuclear Information System (INIS)

    Ozturk, Emine; Sokmen, Ismail

    2013-01-01

    In this study, the effects of hydrostatic pressure and temperature on the linear and nonlinear intersubband transitions and the refractive index changes in the conduction band of square and graded quantum well (QW) are theoretically calculated within the framework of effective mass approximation. Results obtained show that the energy levels in different QWs and intersubband properties can be modified and controlled by the hydrostatic pressure and temperature. The modulation of the absorption coefficients and the refractive index changes which can be suitable for good performance optical modulators and various infrared optical device applications can be easily obtained by tuning the temperature and the hydrostatic pressure. - Highlights: ► Linear and nonlinear optical processes can be changed by pressure and temperature. ► Magnitude and energy of absorption peaks decrease as pressure increases. ► Refractive index changes in magnitude and energy decrease by increasing pressure. ► Energy differences are dependent on pressure, temperature and QW shapes. ► By increasing pressure we can obtain redshift in the optical transitions. ► For SQW, the absorption spectrum shows blueshift as the temperature increases. ► For GQW, the absorption spectrum shows redshift by temperature.

  15. Multicultural Group Work on Field Excursions to Promote Student Teachers' Intercultural Competence

    Science.gov (United States)

    Brendel, Nina; Aksit, Fisun; Aksit, Selahattin; Schrüfer, Gabriele

    2016-01-01

    As a response to the intercultural challenges of Geography Education, this study seeks to determine factors fostering intercultural competence of student teachers. Based on a one-week multicultural field excursion of eight German and eight Turkish students in Kayseri (Turkey) on Education for Sustainable Development, we used qualitative interviews…

  16. Design and fabrication of inner-selective thin-film composite (TFC) hollow fiber modules for pressure retarded osmosis (PRO)

    KAUST Repository

    Wan, Chun Feng

    2016-08-03

    Pressure retarded osmosis (PRO) is a promising technology to harvest the renewable osmotic energy from salinity gradients. There are great progresses in the fabrication of PRO membranes in the last decade. Thin-film composite (TFC) hollow fibers have been widely studied and demonstrated superior performance. However, the lack of effective TFC hollow fiber modules hinders the commercialization of the PRO technology. Knowledge and experiences to fabricate TFC hollow fiber modules remain limited in the open literature. In this study, we aim to reveal the engineering and science on how to fabricate TFC hollow fiber modules including the formation of inner-selective polyamide layers and the repair of leakages. TFC-PES hollow fiber modules with 30% and 50% packing densities have been successfully fabricated, showing peak power densities of 20.0 W/m2 and 19.4 W/m2, respectively, at 20 bar using 1 M NaCl solution and DI water as feeds. The modules may be damaged during handling and high pressure testing. The repaired modules have a power density of 18.2 W/m2, 91% of the power densities of the undamaged ones. This study would make up the gap between TFC membrane fabrication and TFC membrane module fabrication in the membrane industry. © 2016 Elsevier B.V.

  17. Design and fabrication of inner-selective thin-film composite (TFC) hollow fiber modules for pressure retarded osmosis (PRO)

    KAUST Repository

    Wan, Chun Feng; Li, Bofan; Yang, Tianshi; Chung, Neal Tai-Shung

    2016-01-01

    Pressure retarded osmosis (PRO) is a promising technology to harvest the renewable osmotic energy from salinity gradients. There are great progresses in the fabrication of PRO membranes in the last decade. Thin-film composite (TFC) hollow fibers have been widely studied and demonstrated superior performance. However, the lack of effective TFC hollow fiber modules hinders the commercialization of the PRO technology. Knowledge and experiences to fabricate TFC hollow fiber modules remain limited in the open literature. In this study, we aim to reveal the engineering and science on how to fabricate TFC hollow fiber modules including the formation of inner-selective polyamide layers and the repair of leakages. TFC-PES hollow fiber modules with 30% and 50% packing densities have been successfully fabricated, showing peak power densities of 20.0 W/m2 and 19.4 W/m2, respectively, at 20 bar using 1 M NaCl solution and DI water as feeds. The modules may be damaged during handling and high pressure testing. The repaired modules have a power density of 18.2 W/m2, 91% of the power densities of the undamaged ones. This study would make up the gap between TFC membrane fabrication and TFC membrane module fabrication in the membrane industry. © 2016 Elsevier B.V.

  18. Module-scale analysis of pressure retarded osmosis: performance limitations and implications for full-scale operation.

    Science.gov (United States)

    Straub, Anthony P; Lin, Shihong; Elimelech, Menachem

    2014-10-21

    We investigate the performance of pressure retarded osmosis (PRO) at the module scale, accounting for the detrimental effects of reverse salt flux, internal concentration polarization, and external concentration polarization. Our analysis offers insights on optimization of three critical operation and design parameters--applied hydraulic pressure, initial feed flow rate fraction, and membrane area--to maximize the specific energy and power density extractable in the system. For co- and counter-current flow modules, we determine that appropriate selection of the membrane area is critical to obtain a high specific energy. Furthermore, we find that the optimal operating conditions in a realistic module can be reasonably approximated using established optima for an ideal system (i.e., an applied hydraulic pressure equal to approximately half the osmotic pressure difference and an initial feed flow rate fraction that provides equal amounts of feed and draw solutions). For a system in counter-current operation with a river water (0.015 M NaCl) and seawater (0.6 M NaCl) solution pairing, the maximum specific energy obtainable using performance properties of commercially available membranes was determined to be 0.147 kWh per m(3) of total mixed solution, which is 57% of the Gibbs free energy of mixing. Operating to obtain a high specific energy, however, results in very low power densities (less than 2 W/m(2)), indicating that the trade-off between power density and specific energy is an inherent challenge to full-scale PRO systems. Finally, we quantify additional losses and energetic costs in the PRO system, which further reduce the net specific energy and indicate serious challenges in extracting net energy in PRO with river water and seawater solution pairings.

  19. Pressure transients across HEPA filters

    International Nuclear Information System (INIS)

    Gregory, W.; Reynolds, G.; Ricketts, C.; Smith, P.R.

    1977-01-01

    Nuclear fuel cycle facilities require ventilation for health and safety reasons. High efficiency particulate air (HEPA) filters are located within ventilation systems to trap radioactive dust released in reprocessing and fabrication operations. Pressure transients within the air cleaning systems may be such that the effectiveness of the filtration system is questioned under certain accident conditions. These pressure transients can result from both natural and man-caused phenomena: atmospheric pressure drop caused by a tornado or explosions and nuclear excursions initiate pressure pulses that could create undesirable conditions across HEPA filters. Tornado depressurization is a relatively slow transient as compared to pressure pulses that result from combustible hydrogen-air mixtures. Experimental investigation of these pressure transients across air cleaning equipment has been undertaken by Los Alamos Scientific Laboratory and New Mexico State University. An experimental apparatus has been constructed to impose pressure pulses across HEPA filters. The experimental equipment is described as well as preliminary results using variable pressurization rates. Two modes of filtration of an aerosol injected upstream of the filter is examined. A laser instrumentation for measuring the aerosol release, during the transient, is described

  20. Study of the thermal and hydraulic phenomena occurring during power excursion on a heated test section; Etude des phenomenes thermiques et hydrauliques accompagnant une excursion rapide de puissance sur un canal chauffant

    Energy Technology Data Exchange (ETDEWEB)

    Nyer, M. [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1969-07-01

    The thermal and hydrodynamic phenomena occurring during a power excursion were studied in an out-of-pile loop with a water cooled channel at low pressure (1 to 4 atm. abs. ). Circular and rectangular test sections with electrically heated walls of two different thermal diffusivity materials(aluminium and stainless steel) were used. The rectangular test sections were 600 mm long, 35 mm wide and had a 2, 9 mm gap; they simulate two half plates of the M.T.R. fuel element. Natural or forced convection are possible in the test section; the water height above it can be varied from 2.8 to 8 meters and the maximum allowed pressure at its outlet is 4 atm. abs.The heating source is a series of lead batteries which is able to generate, for short periods of time, 85 volts and 25000 amperes; linear, square or exponential power rise versus time can be realized. A 14 channels tape recorder (0-10 000 Hz bandwidth; is used for the measurements of temperature (8/100 mm diameter thermocouple), pressure ('Statham' pressure transducers) and void fraction (X rays). More than 500 tests have been carried out. The influence of the initial water temperature, flow rate, pressure, water height on the water ejections, pressure variations and void fraction in the test section were studied. Tests with energies up to 3000 W/cm in 50 milliseconds were attempted. The energy above which the instabilities appear was determined. An interpretation of the observed phenomena and a simplified theoretical model are presented. [French] Les phenomenes thermiques et hydrodynamiques qui apparaissent au cours d'une excursion de puissance ont ete etudies sur un canal refroidi par de l'eau a basse pression situe sur une installation hors pile. On a utilise des sections d'essais de geometrie cylindrique ou parallipedique dont les parois chauffees par effet Joule sont constituees de materiaux de diffusivite calorifique differente (aluminium et acier inoxydable). La section d

  1. Analysis of LOF/TOP excursions in the SNR-300 Zielkern core with a stress controlled rip extension after failure

    International Nuclear Information System (INIS)

    Royl, P.

    1987-07-01

    An unprotected loss of flow (ULOF) accident can result in energetic power excursions due to reactivity effects from in-pile fuel motion and compaction after a near midplane failure of fuel pins in unvoided regions of the core (loss of flow driven transient overpower or LOF/TOP excursions). These excursions are strongly mitigated by a propagation of the failure rip, which reduces the fuel compaction and enhances fuel sweep-out. A simple model has been introduced into the SAS3D code in which this propagation is restricted to the expansion of the void zone that is firmed in the coolant channel due to thermal interactions of fuel and sodium (FCI) after failure. The rip propagation is demonstrated in this report in all investigated cases to be a strong mitigator that will limit the fuel compaction effects in the region where they originate

  2. An investigation into the effects of frequency-modulated transcutaneous electrical nerve stimulation (TENS) on experimentally-induced pressure pain in healthy human participants.

    Science.gov (United States)

    Chen, Chih-Chung; Johnson, Mark I

    2009-10-01

    Frequency-modulated transcutaneous electrical nerve stimulation (TENS) delivers currents that fluctuate between preset boundaries over a fixed period of time. This study compared the effects of constant-frequency TENS and frequency-modulated TENS on blunt pressure pain in healthy human volunteers. Thirty-six participants received constant-frequency TENS (80 pps), frequency-modulated TENS (20 to 100 pps), and placebo (no current) TENS at a strong nonpainful intensity in a randomized cross-over manner. Pain threshold was taken from the forearm using pressure algometry. There were no statistical differences between constant-frequency TENS and frequency-modulated TENS after 20 minutes (OR = 1.54; CI, 0.29, 8.23, P = 1.0). Both constant-frequency TENS and frequency-modulated TENS were superior to placebo TENS (OR = 59.5, P TENS does not influence hypoalgesia to any greater extent than constant-frequency TENS when currents generate a strong nonpainful paraesthesia at the site of pain. The finding that frequency-modulated TENS and constant-frequency TENS were superior to placebo TENS provides further evidence that a strong yet nonpainful TENS intensity is a prerequisite for hypoalgesia. This study provides evidence that TENS, delivered at a strong nonpainful intensity, increases pain threshold to pressure algometry in healthy participants over and above that seen with placebo (no current) TENS. Frequency-modulated TENS does not increase hypoalgesia to any appreciable extent to that seen with constant-frequency TENS.

  3. The impact of feedwater and condensate return excursions on boiler system component failures

    Energy Technology Data Exchange (ETDEWEB)

    Esmacher, Mel J. [GE Water and Process Technologies, The Woodlands, TX (United States); Rossi, Anthony [GE Water and Process Technologies, Trevose, PA (United States)

    2010-02-15

    During boiler operation, the transport of contaminants in boiler feedwater or condensate return via hardness excursions or transport of metal oxides due to corrosion can cause fouling and subsequent tube failure due to under-deposit corrosion or overheating. Case histories are reviewed and suitable corrective actions discussed. (orig.)

  4. Preliminary Studies Of A Phase Modulation Technique For Measuring Chromaticity

    International Nuclear Information System (INIS)

    Tan, C.-Y.

    2006-01-01

    The classical method for measuring chromaticity is to slowly modulate the RF frequency and then measure the betatron tune excursion. The technique that is discussed in this paper instead modulates the phase of the RF and then the chromaticity is obtained by phase demodulating the betatron tune. This technique requires knowledge of the betatron frequency in real time in order for the phase to be demodulated. Fortunately, the Tevatron has a tune tracker based on the phase locked loop principle which fits this requirement. A preliminary study with this technique has showed that it is a promising method for doing continuous chromaticity measurement and raises the possibility of doing successful chromaticity feedback with it

  5. Raman and photo-modulated reflectivity studies of ZnTe/InAs semiconductor heterostructure under hydrostatic pressure

    International Nuclear Information System (INIS)

    Thomas, R.J.; Boley, M.S.; Chandrasekhar, H.R.; Chandrasekhar, M.; Parks, C.; Ramdas, A.K.; Han, J.; Kobayashi, M.; Gunshor, R.L.

    1994-01-01

    The photo--modulated reflectivity spectrum of a biaxially-strained pseudomorphic ZnTe epilayer, grown on an InAs epilayer by molecular beam epitaxy is studied as a function of applied hydrostatic pressure at 80 K. With increasing hydrostatic compression, the biaxially compressive strain is progressively compensated by the pressure induced tensile strain. At approximately 55 kbars the epilayer becomes strain free, and is under a biaxial tension at higher pressures. The separation between the heavy hole and light hole signatures is superlinear in pressure, suggestive of a pressure dependent shear deformation potential constant for the valence and conduction bands. We also compare the pressure dependence of the Raman LO phonon of the ZnTe epilayer on InAs with that of a bulk ZnTe sample at 13 K. The pressure dependent strain is found to be linear. Accurate values of the first order strain derivatives of the LO-phonons and mode Grueneisen constants are obtained. copyright 1994 American Institute of Physics

  6. Estimation method for first excursion probability of secondary system with impact and friction using maximum response

    International Nuclear Information System (INIS)

    Shigeru Aoki

    2005-01-01

    The secondary system such as pipings, tanks and other mechanical equipment is installed in the primary system such as building. The important secondary systems should be designed to maintain their function even if they are subjected to destructive earthquake excitations. The secondary system has many nonlinear characteristics. Impact and friction characteristic, which are observed in mechanical supports and joints, are common nonlinear characteristics. As impact damper and friction damper, impact and friction characteristic are used for reduction of seismic response. In this paper, analytical methods of the first excursion probability of the secondary system with impact and friction, subjected to earthquake excitation are proposed. By using the methods, the effects of impact force, gap size and friction force on the first excursion probability are examined. When the tolerance level is normalized by the maximum response of the secondary system without impact or friction characteristics, variation of the first excursion probability is very small for various values of the natural period. In order to examine the effectiveness of the proposed method, the obtained results are compared with those obtained by the simulation method. Some estimation methods for the maximum response of the secondary system with nonlinear characteristics have been developed. (author)

  7. Standard Test Method for Saltwater Pressure Immersion and Temperature Testing of Photovoltaic Modules for Marine Environments

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2010-01-01

    1.1 This test method provides a procedure for determining the ability of photovoltaic modules to withstand repeated immersion or splash exposure by seawater as might be encountered when installed in a marine environment, such as a floating aid-to-navigation. A combined environmental cycling exposure with modules repeatedly submerged in simulated saltwater at varying temperatures and under repetitive pressurization provides an accelerated basis for evaluation of aging effects of a marine environment on module materials and construction. 1.2 This test method defines photovoltaic module test specimens and requirements for positioning modules for test, references suitable methods for determining changes in electrical performance and characteristics, and specifies parameters which must be recorded and reported. 1.3 This test method does not establish pass or fail levels. The determination of acceptable or unacceptable results is beyond the scope of this test method. 1.4 The values stated in SI units are to be ...

  8. Neonatal/infant validation study of the CAS model 740 noninvasive blood pressure monitor with the Orion/MaxIQ NIBP module.

    Science.gov (United States)

    Lang, Sean M; Giuliano, John S; Carroll, Christopher L; Rosenkrantz, Ted S; Eisenfeld, Leonard

    2014-06-01

    Blood pressure monitoring is an essential vital sign when caring for critically ill children. Invasive monitoring is considered the gold standard, but is not always feasible. The following study compared the CAS model 740 noninvasive blood pressure monitor with the Orion/MaxIQ NIBP module with the reference (invasive arterial measurement). We evaluated the validity of the system using the criteria provided by the Association for the Advancement of Medical Instrumentation. We performed paired measurements of 29 critically ill neonates and children. For individual paired comparisons, the mean difference in the systolic blood pressure was 2.42 mmHg (SD ± 6.3). The mean difference in the diastolic blood pressure was -1.29 mmHg (SD ± 5.45). The percentage of readings within 5, 10, and 15 mmHg for systolic blood pressure was 65.6, 86.0, and 96.8%, respectively. The percentage of readings within 5, 10, and 15 mmHg for diastolic blood pressure was 77.7, 93, and 95.5%, respectively. The CAS model 740 noninvasive blood pressure monitor with the Orion/MaxIQ NIBP module fulfills the accuracy performance criteria of the Association for the Advancement of Medical Instrumentation. This model may allow for rapid and accurate noninvasive blood pressure monitoring in neonates and children.

  9. Analyses of hypothetical nuclear criticality excursions in 10- and 20-MW freezer/sublimer vessels

    International Nuclear Information System (INIS)

    Haught, C.F.; Jordan, W.C.; Basoglu, B.; Dodds, H.L.; Wilkinson, A.D.

    1995-01-01

    A theoretical model is used to predict the consequences of a postulated hypothetical nuclear criticality excursion in a freezer/sublimer (F/S). Previous work has shown that an intrusion of water into a F/S may result in a critical configuration. A first attempt is made to model the neutronic and thermal-hydraulic phenomena occurring during a criticality excursion involving both uranium hexafluoride (UF 6 ) and uranyl fluoride (UO 2 F 2 ) solution, which is present in the F/S during upset conditions. The model employs point neutronics coupled with simple thermal hydraulics. Reactivity feedback from changes in the properties of the system are included in the model. The excursion is studied in a 10-MW F/S with an initial load of 3,500 kg of 5% weight enriched UF 6 and in a 20-MW F/S with an initial load of 6,800 kg of 2% weight enriched UF 6 . The magnitude of the fission release determined in this work is 5.93 x 10 18 fissions in the 10-MW F/S and 4.21 x 10 18 fissions in the 20-MW F/S. In order to demonstrate the reliability of the techniques used in this work, a limited validation study was conducted by comparing the fission release and peak fission rate determined by this work with experimental results for a limited number of experiments. The agreement between calculations and experiments in the validation study is considered to be satisfactory. The calculational results for the hypothetical accidents in the two F/S vessels appear reasonable

  10. Pressure-modulated differential scanning calorimetry. An approach to the continuous, simultaneous determination of heat capacities and expansion coefficients.

    Science.gov (United States)

    Boehm, K; Rösgen, J; Hinz, H-J

    2006-02-15

    A new method is described that permits the continuous and synchronous determination of heat capacity and expansibility data. We refer to it as pressure-modulated differential scanning calorimetry (PMDSC), as it involves a standard DSC temperature scan and superimposes on it a pressure modulation of preselected format. The power of the method is demonstrated using salt solutions for which the most accurate heat capacity and expansibility data exist in the literature. As the PMDSC measurements could reproduce the parameters with high accuracy and precision, we applied the method also to an aqueous suspension of multilamellar DSPC vesicles for which no expansibility data had been reported previously for the transition region. Excellent agreement was obtained between data from PMDSC and values from independent direct differential scanning densimetry measurements. The basic theoretical background of the method when using sawtooth-like pressure ramps is given under Supporting Information, and a complete statistical thermodynamic derivation of the general equations is presented in the accompanying paper.

  11. Low pressure injection sequence sensitivity study of the M1 module of MEDICI

    International Nuclear Information System (INIS)

    Corradini, M.L.; Moses, G.A.; Norkus, J.K.; Welzbacker, R.T.

    1985-01-01

    In order to assess the consequences of a PWR containment failure and the ensuing radiological source term following a severe reactor accident, it is necessary to understand the ex-vessel behavior of the molten core. The M1 module of MEDICI models the dynamic fuel-coolant mixing, energetic interaction, and ejection of fuel and coolant from the reactor cavity following such an accident. A sensitivity study of the low pressure injection sequence was performed utilizing a Box-Behnken statistical design to treat five sets of input variables considered to be significant in the mixing and steam explosion processes. The low pressure injection sequence was studied in which the molten corium is modeled as a pour stream entering the cavity without entraining or sweeping out fuel or coolant

  12. A one night stand? Reproductive excursions of female roe deer as a breeding dispersal tactic

    Czech Academy of Sciences Publication Activity Database

    Debeffe, L.; Focardi, S.; Bonenfant, Ch.; Hewison, A. J. M.; Morellet, N.; Vanpé, C.; Heurich, M.; Kjellander, P.; Linnell, J. D. C.; Mysterud, A.; Pellerin, M.; Šustr, Pavel; Urbano, F.; Cagnacci, F.

    2014-01-01

    Roč. 176, č. 2 (2014), s. 431-443 ISSN 0029-8549 Institutional support: RVO:67179843 Keywords : Mate choice * Inbreeding avoidance * GPS telemetry * Rut excursion * Ungulate Subject RIV: EH - Ecology, Behaviour Impact factor: 3.093, year: 2014

  13. Further development and verification of the calculating programme Felix for the simulation of criticality excursions

    International Nuclear Information System (INIS)

    Weber, J.; Denk, W.

    1985-01-01

    An improved version of the FELIX programme was applied to varify excursion experiments 01, 03 through 07, and 13. The correspondence of experiments and verification was good. Programme points to be further developed are shown. (orig.) [de

  14. The diode pump: its application to nuclear particle counting and to the detection of rapid neutronic power excursions in atomic piles (1962); La pompe a diodes, son application au comptage de particules nucleaires et a la detection des excursions rapides de puissance neutronique d'une pile atomique (1962)

    Energy Technology Data Exchange (ETDEWEB)

    Nicolo, G [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1962-05-15

    This work deals in particular with three applications of an electronic device whose principle is based on that of the diode pump. 1- Linear response circuit 2- Logarithmic response circuit 3- Detection of neutronic power excursions in atomic piles using a circuit or a combination of several circuits of the linear response type. Each of the applications has been studied theoretically and experimentally. Finally, the detection of rapid power excursions is extensively discussed with reference to the many methods available, emphasis being laid on the rapidity of the electronic response. (author) [French] Cet ouvrage traite plus particulierement de trois applications d'un dispositif electronique dont le principe de fonctionnement est base sur celui de la pompe a diodes. 1- Circuit a reponse lineaire 2- Circuit a reponse logarithmique 3- Detection des excursions de puissance neutronique d'une pile atomique a l'aide d'un circuit ou d'une association de plusieurs circuits a reponse lineaire. Chacune des applications fait l'objet d'une etude theorique et experimentale. Enfin, la detection des excursions rapides de puissance est tres largement discutee a travers plusieurs methodes, notamment sur la partie concernant la rapidite de reponse de l'electronique. (auteur)

  15. Translator’s inferential excursions, with imagination in the background

    Directory of Open Access Journals (Sweden)

    Bożena Tokarz

    2014-01-01

    Full Text Available In a literary work, signals that trigger reader’s inferential excursions allow the reader’s imagination to identify with and control the represented world. They constitute an important element of sense-generating mechanism. Thanks to imagination, the translator imitates the inferential mechanism of the original on various level’s of the text’s structure, activating the imagination of the reader. The translator’s imagination is bi- or multivalent in having the linguistic-semiotic, literary, and cultural quality. Although it manifests itself in language, it goes beyond the boundaries of language. Imagination is a form of consciousness which has no object of its own, and a medium connecting a specific non-imaginary knowledge with representations. It constitutes a mind faculty shaped on the basis of sensory and mental perception. It is derived from individual principles of perception and cognition data processing. It usually requires a stymulus to activate the capabilities of the imagining subject. As a mind faculty, imagination is based on the mental capability common to all people, which is the ability to create chains of associations.Translator’s respect for inferential excursions in the original text is necessary for retaining the original meaning, regardless of whether they occur on the phonetic-phonological level (as in Ionesco’s The Chairs, or on the level of image-semantic and syntactic relations (as in translation of Apollinaire’s Zone, or on the level of syntax (as in translation of Mrożek’s short stories into Slovenian, or on the level of cultural communication (as in Slovenian translation of Gombrowicz’s Trans-Atlantic.

  16. Comparison of dynamic balance in collegiate field hockey and football players using star excursion balance test.

    Science.gov (United States)

    Bhat, Rashi; Moiz, Jamal Ali

    2013-09-01

    The preliminary study aimed to compare dynamic balance between collegiate athletes competing or training in football and hockey using star excursion balance test. A total thirty university level players, football (n = 15) and field hockey (n = 15) were participated in the study. Dynamic balance was assessed by using star excursion balance test. The testing grid consists of 8 lines each 120 cm in length extending from a common point at 45° increments. The subjects were instructed to maintain a stable single leg stance with the test leg with shoes off and to reach for maximal distance with the other leg in each of the 8 directions. A pencil was used to point and read the distance to which each subject's foot reached. The normalized leg reach distances in each direction were summed for both limbs and the total sum of the mean of summed normalized distances of both limbs were calculated. There was no significant difference in all the directions of star excursion balance test scores in both the groups. Additionally, composite reach distances of both groups also found non-significant (P=0.5). However, the posterior (P=0.05) and lateral (P=0.03) normalized reach distances were significantly more in field hockey players. Field hockey players and football players did not differ in terms of dynamic balance.

  17. Electronically-Scanned Pressure Sensors

    Science.gov (United States)

    Coe, C. F.; Parra, G. T.; Kauffman, R. C.

    1984-01-01

    Sensors not pneumatically switched. Electronic pressure-transducer scanning system constructed in modular form. Pressure transducer modules and analog to digital converter module small enough to fit within cavities of average-sized wind-tunnel models. All switching done electronically. Temperature controlled environment maintained within sensor modules so accuracy maintained while ambient temperature varies.

  18. Carbon isotopic record from Upper Devonian carbonates at Dongcun in Guilin, southern China, supporting the world-wide pattern of carbon isotope excursions during Frasnian-Famennian transition

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Two positive δ13C excursions are presented in records from the Frasnian-Famennian (F-F) marine carbonate sediments in Europe, America, Africa, and Australia, having been considered as a worldwide pattern, and attributed to enhanced organic carbon burial during the F-F biological mass extinction. However, this worldwide pattern has not been revealed from the well-deposited Late Devonian sequences in southern China. In this paper, a detailed investigation has been made on the Late Devonian section at Dongcun, Guilin, southern China to constrain perturbations in δ13C of carbonates in the F-F deposited sequence. The result from this section also indicates two positive δ13C excursions during the F-F transition. The first excursion with an amplitude of 1.5‰ occurred at the bottom of linguiformis Zone, later than the early excursion existing in the Late rhenana Zone of the Late Devonian profiles in other continents, especially, in central Europe. This difference has been expected to be a result as conodont Palmatolepis linguiformis occurred earlier in southern China than other sites. The second excursion with an amplitude of 2.1‰ is located at the F-F boundary, same as the records from other continents. This result strongly supports the view that two carbon isotope positive excursions during the F-F transition are common in carbonate sediments, resulting from worldwide increases of organic carbon burial intensity.

  19. Devil's staircase of odd-number charge order modulations in divalent β -vanadium bronzes under pressure

    Science.gov (United States)

    Yamauchi, Touru; Ueda, Hiroaki; Ohwada, Kenji; Nakao, Hironori; Ueda, Yutaka

    2018-03-01

    A common characteristic of quasi-one-dimensional (q1D) conductors β -A0.33V2O5 (A = Li, Na, and Ag) is that the charge ordering (CO), the ground state (GS) at ambient pressure, and the superconducting (SC) phases, the GS under high pressure, are competing with each other. We have explored high-pressure properties of divalent β -vanadium bronzes, β -A0.33V2O5 (A = Ca, Sr, and Pb), which are A -cation stoichiometry finely controlled single-crystal/powder samples, and found the absence of the SC phase. In these observations, however, we observed enormous and novel phase transitions, a kind of "devil's staircase"-type phase transitions in the charge ordering (CO) phases. The most surprising discovery in this devil's staircase, which was found mainly in β -Sr0.33V2O5 , is that all the charge modulation vectors of many kinds of CO phases can be represented as a primitive lattice translation vector along the b axis multiplied by several odd numbers. This discovery surely demonstrates interplay between the charge degree freedom and the crystallographic symmetry. We propose two possible mechanisms to explain this phenomenon: "self-charge transfer (carrier redistribution)" between the two subsystems in these compounds and "sequential symmetry reduction" that was discussed in Landau theory of phase transitions. In β -Ca0.33V2O5 we also found a P -T phase diagram similar in outlook but different in detail. The devil's staircase was also observed but it is an incomplete one. Furthermore, the charge modulation vectors in it are shorter than those in β -Sr0.33V2O5 . In β -Pb0.33V2O5 , which has no CO phase at ambient pressure, the pressure-induced antiferromagnetic ordering was observed at around 50 K above 0.5 GPa. Using these two kinds of mechanisms, we also explain the global high-pressure properties in all the stoichiometric divalent β -vanadium bronzes, which were observed as a wide variety of electromagnetic states. In addition, we also discuss a possible key for

  20. Prediction of the pressure-time history due to fuel-sodium interaction in a subassembly

    International Nuclear Information System (INIS)

    Jacobs, H.

    1975-01-01

    A local cooling disturbance may lead to complete voiding of a subassembly and melt down of the fuel pins. Thus molten fuel may be accumulated and mixed with liquid sodium returning accidentally into the subassembly. The resulting fuel-sodium interaction (FSI) produces a pressure load on the surrounding core structures. It is necessary to prove that the corresponding core deformation neither initiates a nuclear excursion nor renders the shut down system inoperable. This requires the knowledge of the initiating FSI pressure time history. In this paper a theoretical pressure time history is presented which differs completely from all calculations known so far. (Auth.)

  1. Relationship of medial gastrocnemius relative fascicle excursion and ankle joint power and work performance during gait in typically developing children: A cross-sectional study.

    Science.gov (United States)

    Martín Lorenzo, Teresa; Albi Rodríguez, Gustavo; Rocon, Eduardo; Martínez Caballero, Ignacio; Lerma Lara, Sergio

    2017-07-01

    Muscle fascicles lengthen in response to chronic passive stretch through in-series sarcomere addition in order to maintain an optimum sarcomere length. In turn, the muscles' force generating capacity, maximum excursion, and contraction velocity is enhanced. Thus, longer fascicles suggest a greater capacity to develop joint power and work. However, static fascicle length measurements may not be taking sarcomere length differences into account. Thus, we considered relative fascicle excursions through passive ankle dorsiflexion may better correlate with the capacity to generate joint power and work than fascicle length. Therefore, the aim of the present study was to determine if medial gastrocnemius relative fascicle excursions correlate with ankle joint power and work generation during gait in typically developing children. A sample of typically developing children (n = 10) were recruited for this study and data analysis was carried out on 20 legs. Medial gastrocnemius relative fascicle excursion from resting joint angle to maximum dorsiflexion was estimated from trigonometric relations of medial gastrocnemius pennation angle and thickness obtained from B-mode real-time ultrasonography. Furthermore, a three-dimensional motion capture system was used to obtain ankle joint work and power during the stance phase of gait. Significant correlations were found between relative fascicle excursion and peak power absorption (-) r(14) = -0.61, P = .012 accounting for 31% variability, positive work r(18) = 0.56, P = .021 accounting for 31% variability, and late stance positive work r(15) = 0.51, P = .037 accounting for 26% variability. The large unexplained variance may be attributed to mechanics of neighboring structures (e.g., soleus or Achilles tendon mechanics) and proximal joint kinetics which may also contribute to ankle joint power and work performance, and were not taken into account. Further studies are encouraged to provide greater insight

  2. Low-pressure

    Energy Technology Data Exchange (ETDEWEB)

    Baker, Richard [Membrane Technology And Research, Inc., Newark, CA (United States); Kniep, Jay [Membrane Technology And Research, Inc., Newark, CA (United States); Hao, Pingjiao [Membrane Technology And Research, Inc., Newark, CA (United States); Chan, Chi Cheng [Membrane Technology And Research, Inc., Newark, CA (United States); Nguyen, Vincent [Membrane Technology And Research, Inc., Newark, CA (United States); Huang, Ivy [Membrane Technology And Research, Inc., Newark, CA (United States); Amo, Karl [Membrane Technology And Research, Inc., Newark, CA (United States); Freeman, Brice [Membrane Technology And Research, Inc., Newark, CA (United States); Fulton, Don [Membrane Technology And Research, Inc., Newark, CA (United States); Ly, Jennifer [Membrane Technology And Research, Inc., Newark, CA (United States); Lipscomb, Glenn [Membrane Technology And Research, Inc., Newark, CA (United States); Lou, Yuecun [Membrane Technology And Research, Inc., Newark, CA (United States); Gogar, Ravikumar [Membrane Technology And Research, Inc., Newark, CA (United States)

    2015-01-29

    This final technical progress report describes work conducted by Membrane Technology and Research, Inc. (MTR) for the Department of Energy (DOE NETL) on development of low-pressure membrane contactors for carbon dioxide (CO2) capture from power plant flue gas (award number DE-FE0007553). The work was conducted from October 1, 2011 through September 30, 2014. The overall goal of this three-year project was to build and operate a prototype 500 m2 low-pressure sweep membrane module specifically designed to separate CO2 from coal-fired power plant flue gas. MTR was assisted in this project by a research group at the University of Toledo, which contributed to the computational fluid dynamics (CFD) analysis of module design and process simulation. This report details the work conducted to develop a new type of membrane contactor specifically designed for the high-gas-flow, low-pressure, countercurrent sweep operation required for affordable membrane-based CO2 capture at coal power plants. Work for this project included module development and testing, design and assembly of a large membrane module test unit at MTR, CFD comparative analysis of cross-flow, countercurrent, and novel partial-countercurrent sweep membrane module designs, CFD analysis of membrane spacers, design and fabrication of a 500 m2 membrane module skid for field tests, a detailed performance and cost analysis of the MTR CO2 capture process with low-pressure sweep modules, and a process design analysis of a membrane-hybrid separation process for CO2 removal from coal-fired flue gas. Key results for each major task are discussed in the report.

  3. Image simulation of high-speed imaging by high-pressure gas ionization detector

    International Nuclear Information System (INIS)

    Miao Jichen; Liu Ximing; Wu Zhifang

    2005-01-01

    The signal of the neighbor pixels is cumulated in Freight Train Inspection System because data fetch time is shorter than ion excursion time. This paper analyzes the pertinency of neighbor pixels and designs computer simulation method to generate some emulate images such as indicator image. The result indicates the high-pressure gas ionization detector can be used in high-speed digital radiography field. (authors)

  4. Under Pressure: Response Urgency Modulates Striatal and Insula Activity during Decision-Making under Risk

    OpenAIRE

    Jones, Catherine L.; Minati, Ludovico; Harrison, Neil A.; Ward, Jamie; Critchley, Hugo D.

    2011-01-01

    When deciding whether to bet in situations that involve potential monetary loss or gain (mixed gambles), a subjective sense of pressure can influence the evaluation of the expected utility associated with each choice option. Here, we explored how gambling decisions, their psychophysiological and neural counterparts are modulated by an induced sense of urgency to respond. Urgency influenced decision times and evoked heart rate responses, interacting with the expected value of each gamble. Usin...

  5. VENUS-2, Reactor Kinetics with Feedback, 2-D LMFBR Disassembly Excursions

    International Nuclear Information System (INIS)

    Jackson, J.F.; Nicholson, R.B.; Weber, D.P.

    1980-01-01

    1 - Description of problem or function: VENUS-2 is an improved edition of the VENUS fast-reactor disassembly program. It is a two- dimensional (r-z) coupled neutronics-hydrodynamics code that calculates the dynamic behavior of an LMFBR during a prompt-critical disassembly excursion. It calculates the power history and fission energy release as well as the space-time histories of the fuel temperatures, core material pressures, and core material motions. Reactivity feedback effects due to Doppler broadening and reactor material motion are taken into account. 2 - Method of solution: The power and energy release are calculated using a point-kinetics formulation with up to six delayed neutron groups. The reactivity is a combination of an input driving function and feedback effects due to Doppler broadening and material motion. An adiabatic model is used to calculate the temperature increase throughout the reactor based on an initial temperature distribution and power profile provided as input data. These temperatures are, in turn, converted to fuel pressures through one of several equation of state options provided. The material motion that results from the pressure buildup is calculated by a direct finite difference solution of a set of two-dimensional (r-z) hydrodynamics equations. This is done in Lagrangian coordinates. The reactivity change associated with this motion is calculated by first-order perturbation theory. The displacements are also used to adjust the fuel densities as required for the density dependent equation-of- state option. An automatic time-step-size selection scheme is provided. 3 - Restrictions on the complexity of the problem: VENUS-2 is written so that the dimensions of the storage arrays can be readily changed to accommodate a broad range of problem sizes. In the base version, the total number of mesh intervals is restricted such that (NR+3)*(NZ+3) is less than 700, where NR and NZ are the total number of mesh intervals in the r and z

  6. Enabling the Development of Student Teacher Professional Identity through Vicarious Learning during an Educational Excursion

    Science.gov (United States)

    Steenekamp, Karen; van der Merwe, Martyn; Mehmedova, Aygul Salieva

    2018-01-01

    This paper explores the views of student teachers who were provided vicarious learning opportunities during an educational excursion, and how the learning enabled them to develop their teacher professional identity. This qualitative research study, using a social-constructivist lens highlights how vicarious learning influenced student teachers'…

  7. Is portal venous pressure modulation still indicated for all recipients in living-donor liver transplantation?

    Science.gov (United States)

    Yao, Siyuan; Kaido, Toshimi; Uozumi, Ryuji; Yagi, Shintaro; Miyachi, Yosuke; Fukumitsu, Ken; Anazawa, Takayuki; Kamo, Naoko; Taura, Kojiro; Okajima, Hideaki; Uemoto, Shinji

    2018-04-30

    There is a consensus that portal venous pressure (PVP) modulation prevents portal hypertension (PHT) and consequent complications after adult living donor liver transplantation (ALDLT). However, PVP-modulation strategies need updating based on most recent findings. We examined our 10-year experience of PVP modulation and reevaluate whether it is necessary for all recipients or selected recipients in ALDLT. In this retrospective study, 319 patients who underwent ALDLT from 2007 to 2016 were divided into three groups according to the necessity and results of PVP modulation: not indicated (n=189), indicated and successful (n=92), and indicated but failed (n=38). Graft survival and associations with various clinical factors were investigated. PVP modulation was performed mainly by splenectomy to lower final PVP to ≤15 mmHg. Successful PVP modulation improved prognosis that was equivalent to that of patients who did not need modulation, whereas failed modulation was associated with increased incidence of small-for-size syndrome (SFSS) (p=0.003), and early graft loss (EGL) (p=0.006). Among patients with failed modulation, donor age ≥45 years (hazard ratio [HR], 3.67; p=0.02) and ABO incompatibility (HR, 3.90; p=0.01) were independent risk factors for graft loss. Survival analysis showed that PVP >15 mmHg was related to poor prognosis in grafts from either ABO-incompatible or older donor aged ≥45 years (pmodulation is not necessarily required in all recipients. While grafts from both ABO-compatible/identical and young donor can tolerate PHT, lowering PVP to ≤15 mmHg is a key to preventing SFSS and consequent EGL with grafts from either ABO-incompatible or older donors. This article is protected by copyright. All rights reserved. © 2018 by the American Association for the Study of Liver Diseases.

  8. Variations in Star Excursion Balance Test Performance Between High School and Collegiate Football Players.

    Science.gov (United States)

    McCann, Ryan S; Kosik, Kyle B; Beard, Megan Q; Terada, Masafumi; Pietrosimone, Brian G; Gribble, Phillip A

    2015-10-01

    The Star Excursion Balance Test (SEBT) is a reliable inexpensive tool used to assess dynamic postural control deficits and efficacy in the prediction of musculoskeletal injuries, but with little previous consideration for performance differences across age and skill levels. The purpose of this study was to examine differences in SEBT scores between high school and collegiate football players. Three-hundred eighteen high school football players and 180 National Collegiate Athletic Association Division I collegiate football players volunteered to participate. Star Excursion Balance Test scores were obtained bilaterally for anterior (ANT), posterolateral (PL), and posteromedial (PM) directions, and for an overall composite (COMP) score. The mean of 3 trials from each leg was normalized to stance leg length and presented as a percentage score. Bilaterally averaged scores were compared between high school and collegiate football players using separate independent t-tests. A multiple linear backward regression determined the amount of variance in SEBT scores explained by age, mass, and height. Compared with collegiate athletes, high school athletes had lower PL (72.8 ± 11.4% vs. 77.1 ± 10.2%; p football players.

  9. THE HALO MASS FUNCTION FROM EXCURSION SET THEORY. I. GAUSSIAN FLUCTUATIONS WITH NON-MARKOVIAN DEPENDENCE ON THE SMOOTHING SCALE

    International Nuclear Information System (INIS)

    Maggiore, Michele; Riotto, Antonio

    2010-01-01

    A classic method for computing the mass function of dark matter halos is provided by excursion set theory, where density perturbations evolve stochastically with the smoothing scale, and the problem of computing the probability of halo formation is mapped into the so-called first-passage time problem in the presence of a barrier. While the full dynamical complexity of halo formation can only be revealed through N-body simulations, excursion set theory provides a simple analytic framework for understanding various aspects of this complex process. In this series of papers we propose improvements of both technical and conceptual aspects of excursion set theory, and we explore up to which point the method can reproduce quantitatively the data from N-body simulations. In Paper I of the series, we show how to derive excursion set theory from a path integral formulation. This allows us both to derive rigorously the absorbing barrier boundary condition, that in the usual formulation is just postulated, and to deal analytically with the non-Markovian nature of the random walk. Such a non-Markovian dynamics inevitably enters when either the density is smoothed with filters such as the top-hat filter in coordinate space (which is the only filter associated with a well-defined halo mass) or when one considers non-Gaussian fluctuations. In these cases, beside 'Markovian' terms, we find 'memory' terms that reflect the non-Markovianity of the evolution with the smoothing scale. We develop a general formalism for evaluating perturbatively these non-Markovian corrections, and in this paper we perform explicitly the computation of the halo mass function for Gaussian fluctuations, to first order in the non-Markovian corrections due to the use of a top-hat filter in coordinate space. In Paper II of this series we propose to extend excursion set theory by treating the critical threshold for collapse as a stochastic variable, which better captures some of the dynamical complexity of the

  10. Excursions in the catazonal rock complexes of the polyorogenic terrain of Cabo Ortegal (NW Spain)

    NARCIS (Netherlands)

    Vogel, D.E.

    1967-01-01

    This excursion program anticipates the publication of a PhD. thesis (Vogel, in preparation) in this periodical and is intended as a guide to those points at Cabo Ortegal, that are readily accessible, well exposed and of general petrological interest. The described localities are indicated on a small

  11. Temperature measurement on Zircaloy-clad fuel pins during high temperature excursions

    International Nuclear Information System (INIS)

    Meservey, R.H.

    1976-04-01

    The development of a sheathed thermocouple suitable for attachment to zircaloy-clad fuel rods and for use during high temperature (2,800 0 F) excursions under loss-of-coolant accident conditions is described. Development, fabrication, and testing of the thermocouples is covered in detail. In addition, the development of a process for laser welding the thermocouples to fuel rods is discussed. The thermocouples and attachment welds have been tested for resistance to corrosion and nuclear radiation and have been subjected to fast thermal cycle, risetime, and blowdown accident tests

  12. Vertical orbit excursion fixed field alternating gradient accelerators

    Directory of Open Access Journals (Sweden)

    Stephen Brooks

    2013-08-01

    Full Text Available Fixed field alternating gradient (FFAG accelerators with vertical orbit excursion (VFFAGs provide a promising alternative design for rings with fixed-field superconducting magnets. They have a vertical magnetic field component that increases with height in the vertical aperture, yielding a skew quadrupole focusing structure. Scaling-type VFFAGs are found with fixed tunes and no intrinsic limitation on momentum range. This paper presents the first multiparticle tracking of such machines. Proton driver rings to accelerate the 800 MeV beam from the ISIS synchrotron are presented, in terms of both magnet field geometry and longitudinal behavior during acceleration with space charge. The 12 GeV ring produces an output power of at least 2.18 MW. Possible applications of VFFAGs to waste transmutation, hadron therapy, and energy-recovery electron accelerators are also discussed.

  13. Fractionation between inorganic and organic carbon during the Lomagundi (2.22 2.1 Ga) carbon isotope excursion

    Science.gov (United States)

    Bekker, A.; Holmden, C.; Beukes, N. J.; Kenig, F.; Eglinton, B.; Patterson, W. P.

    2008-07-01

    The Lomagundi (2.22-2.1 Ga) positive carbon isotope excursion in shallow-marine sedimentary carbonates has been associated with the rise in atmospheric oxygen, but subsequent studies have demonstrated that the carbon isotope excursion was preceded by the rise in atmospheric oxygen. The amount of oxygen released to the exosphere during the Lomagundi excursion is constrained by the average global fractionation between inorganic and organic carbon, which is poorly characterized. Because dissolved inorganic and organic carbon reservoirs were arguably larger in the Paleoproterozoic ocean, at a time of lower solar luminosity and lower ocean redox state, decoupling between these two variables might be expected. We determined carbon isotope values of carbonate and organic matter in carbonates and shales of the Silverton Formation, South Africa and in the correlative Sengoma Argillite Formation, near the border in Botswana. These units were deposited between 2.22 and 2.06 Ga along the margin of the Kaapvaal Craton in an open-marine deltaic setting and experienced lower greenschist facies metamorphism. The prodelta to offshore marine shales are overlain by a subtidal carbonate sequence. Carbonates exhibit elevated 13C values ranging from 8.3 to 11.2‰ vs. VPDB consistent with deposition during the Lomagundi positive excursion. The total organic carbon (TOC) contents range from 0.01 to 0.6% and δ13C values range from - 24.8 to - 13.9‰. Thus, the isotopic fractionation between organic and carbonate carbon was on average 30.3 ± 2.8‰ ( n = 32) in the shallow-marine environment. The underlying Sengoma shales have highly variable TOC contents (0.14 to 21.94%) and δ13C values (- 33.7 to - 20.8‰) with an average of - 27.0 ± 3.0‰ ( n = 50). Considering that the shales were also deposited during the Lomagundi excursion, and taking δ13C values of the overlying carbonates as representative of the δ13C value of dissolved inorganic carbon during shale deposition, a carbon

  14. Paleointensities of the Auckland Excursion from Volcanic Rocks in New Zealand

    Science.gov (United States)

    Mochizuki, N.; Tsunakawa, H.; Shibuya, H.; Cassidy, J.; Smith, I. E.

    2001-12-01

    Shibuya et al. (1992) reported the Auckland excursion from several basaltic lava flows of monogenetic volcanic centers (Auckland Volcanic Field, New Zealand. The Auckland excursion was recorded in five centers in three intermediate direction groups of north-down, west and south. We carried out paleointensity and rock-magnetic studies in order to obtain the absolute paleointensities associated with three intermediate geomagnetic fields. Thermomagnetic analyses indicated typical Curie temperatures of 150-200, 450-500 and/or 550-580 oC. The Day plot (Day et al., 1977) showed a linear trend in the pseudo-single-domain range of magnetic carriers. Those results, combined with the reflection microscope observations, identified the magnetic carriers as titanomagnetites with wide variation in titanium content and grain size. First, the Coe's version of the Thellier method (Coe, 1967) was applied to the samples. Several samples seemed to give paleointensities ranging from 3.2 to 6.4 μ T (Shibuya and Cassidy, 1995 AGU fall meeting), but they were often affected by thermal alteration in the furnace even from fairly low temperature steps like 200oC. We were forced to introduce correction for thermal alterations in laboratory heating, using low temperature part of the Arai plot. We, therefore, applied the double heating technique (DHT) of Shaw method (Tsunakawa and Shaw, 1994), which was capable of detecting inappropriate results by the ARM correction, to the samples. The low temperature demagnetization (LTD) was combined with DHT (Yamamoto et al., submitted) before AF demagnetization and samples were heated in a vacuum of 10-100 Pa. Sixty-one samples from the five lava flows were subjected to the LTD-DHT Shaw method. Twenty-three of these samples yielded successful results passing the selection criteria. Five out of six paleointensities from the Crater Hill lava were consistent with each other. A mean paleointensity was given to be 10.9+/- 1.9 μ T (N=5) for the Crater Hill

  15. SIMMER-III parametric studies of fuel-steel mixing and radial mesh effects on power excursion in ESFR ULOF transients - 15033

    International Nuclear Information System (INIS)

    Chen, X.N.; Rineiski, A.; Gabrielli, F.; Andriolo, L.; Li, R.; Maschek, W.

    2015-01-01

    This paper deals with SIMMER-III once-through simulations of the first power excursion initiated by an unprotected loss of flow (ULOF) in the Working Horse design of the European Sodium Cooled Fast Reactor (ESFR). Since the sodium void effect is strictly positive in this core and dominant in the transient, a power excursion is initiated by sodium boiling in the ULOF case. Two major effects, namely (1) reactivity effects due to fuel-steel mixing after melting and (2) the radial mesh size, which were not considered initially in SIMMER simulations for ESFR, are studied. The first effect concerns the reactivity difference between the heterogeneous fuel/clad/wrapper configuration and the homogeneous mixture of steel and fuel. The full core homogenization (due to melting) effect is ∼ 2 dollars, though a smaller effect takes place in case of partial core melting. The second effect is due to the SIMMER sub-assembly coarse mesh treatment, where a simultaneous sodium boiling onset in all sub-assemblies belonging to one ring leads to an overestimated reactivity ramp. For investigating the influence of fuel/steel mixing effects, a lumped 'homogenization' reactivity feedback has been introduced, being proportional to the molten steel mass. For improving the coarse mesh treatment, we employ finer radial meshes to take the subchannel effects into account, where the side and interior channels have different coolant velocities and temperatures. The simulation results show that these two effects have significant impacts on the first power excursion after the sodium boiling: both effects delay the power excursion and significantly reduce the height of the power peaks in case of a ULOF

  16. Comparison of excursive occlusal force parameters in post-orthodontic and non-orthodontic subjects using T-Scan® III.

    Science.gov (United States)

    Qadeer, Sarah; Abbas, Ahmed A; Sarinnaphakorn, Lertrit; Kerstein, Robert B

    2018-01-01

    Published studies indicate that orthodontically treated patients demonstrate increased posterior occlusal friction contributing to temporomandibular disorder (TMD) symptoms. This study investigated measured excursive movement occlusal contact parameters and their association with TMD symptoms between non- and post-orthodontic subjects. Twenty-five post-orthodontic and 25 non-orthodontic subjects underwent T-Scan® computerized occlusal analysis to determine their disclusion time (DT), the excursive frictional contacts, and occlusal scheme. Each subject answered a TMD questionnaire to determine the presence or absence of TMD symptoms. Statistical analysis compared the within group and between group differences (p orthodontic and 1.36 s in the non-orthodontic group. In the non-orthodontic group, 72.7% working and 27.3% non-working side contacts were seen, while in the post-orthodontic group, (near equal) 54.7% working and 45.3% non-working side contacts were seen. Presence of canine guidance was seen in 60% of the non-orthodontic group and 24% in the post-orthodontic group. Seventy-two percent of the post orthodontics subjects presented with one or more TMD symptoms. Significantly longer disclusion time, higher posterior frictional contacts, and more TMD symptoms were observed in the post-orthodontic group, suggesting that orthodontic treatment increases posterior tooth friction. Computerized occlusal analysis is an objective diagnostic tool determining the quality of excursive movements following orthodontic treatment.

  17. Diet and exercise training reduce blood pressure and improve autonomic modulation in women with prehypertension.

    Science.gov (United States)

    Sales, Allan R K; Silva, Bruno M; Neves, Fabricia J; Rocha, Natália G; Medeiros, Renata F; Castro, Renata R T; Nóbrega, Antonio C L

    2012-09-01

    Despite mortality from heart disease has been decreasing, the decline in death in women remains lower than in men. Hypertension (HT) is a major risk factor for cardiovascular disease. Therefore, approaches to prevent or delay the onset of HT would be valuable in women. Given this background, we investigated the effect of diet and exercise training on blood pressure (BP) and autonomic modulation in women with prehypertension (PHT). Ten women with PHT (39 ± 6 years, mean ± standard deviation) and ten with normotension (NT) (35 ± 11 years) underwent diet and exercise training for 12 weeks. Autonomic modulation was assessed through heart rate (HR) and systolic BP (SBP) variability, using time and frequency domain analyses. At preintervention, women with PHT had higher SBP (PHT: 128 ± 7 vs. NT: 111 ± 6 mmHg, p 0.05). Moreover, reduction in SBP was associated with augmentation in SDNN (r = -0.46, p diet and exercise training reduced SBP in women with PHT, and this was associated with augmentation in parasympathetic and probably reduction in sympathetic cardiac modulation.

  18. Spatial and temporal patterns of subtidal and intertidal crabs excursions

    Science.gov (United States)

    Silva, A. C. F.; Boaventura, D. M.; Thompson, R. C.; Hawkins, S. J.

    2014-01-01

    Highly mobile predators such as fish and crabs are known to migrate from the subtidal zone to forage in the intertidal zone at high-tide. The extent and variation of these habitat linking movements along the vertical shore gradient have not been examined before for several species simultaneously, hence not accounting for species interactions. Here, the foraging excursions of Carcinus maenas (L.), Necora puber (Linnaeus, 1767) and Cancer pagurus (Linnaeus, 1758) were assessed in a one-year mark-recapture study on two replicated rocky shores in southwest U.K. A comparison between the abundance of individuals present on the shore at high-tide with those present in refuges exposed at low-tide indicated considerable intertidal migration by all species, showing strong linkage between subtidal and intertidal habitats. Estimates of population size based on recapture of marked individuals indicated that an average of ~ 4000 individuals combined for the three crab species, can be present on the shore during one tidal cycle. There was also a high fidelity of individuals and species to particular shore levels. Underlying mechanisms for these spatial patterns such as prey availability and agonistic interactions are discussed. Survival rates were estimated using the Cormack-Jolly-Seber model from multi-recapture analysis and found to be considerably high with a minimum of 30% for all species. Growth rates were found to vary intraspecifically with size and between seasons. Understanding the temporal and spatial variations in predation pressure by crabs on rocky shores is dependent on knowing who, when and how many of these commercially important crab species depend on intertidal foraging. Previous studies have shown that the diet of these species is strongly based on intertidal prey including key species such as limpets; hence intertidal crab migration could be associated with considerable impacts on intertidal assemblages.

  19. Excursions to nuclear facilities in the Federal Republic of Germany

    International Nuclear Information System (INIS)

    1980-12-01

    Promoting young talents in the field of nuclear technology is considered one of the most important tasks the Kerntechnische Gesellschaft e.V. (Society for Nuclear Engineering) tries to fulfill in many ways. It has developed a curriculum for the specialty of nuclear technology, provides funds for attending conferences and gives financial support to student members. In line with these efforts to promote young talents, the Kerntechnische Gesellschaft now submits a list of nuclear facilities where to special excursions may be made in the course of corresponding training programmes. State-owned and private research and development centres, industrial factories and electricity-generating nuclear power plants as well as nuclear fuel cycle centres are thus concerned. (orig.) [de

  20. Traverse across the Nelspruit batholith and the geology of the excursion route between Sabie and Witbank

    International Nuclear Information System (INIS)

    Robb, L.J.; Anhaeusser, C.R.

    1981-01-01

    A geologic survey was done on the traverse across the Nelspruit batholith and the geology of the excursion route between Sabie and Witbank. Rubidium isotopes, strontium 86 and strontium 87 were used to determine the rock age. The petrogenetic aspects relating to the Nelspruit batholith were also studied

  1. An information, education and communication module to reduce dietary salt intake and blood pressure among tea garden workers of Assam

    Directory of Open Access Journals (Sweden)

    Prasanta K. Borah

    2018-03-01

    Full Text Available Objective: High salt diet increases blood pressure. Tea garden workers (TGW of Assam, India have high (60.8% prevalence of hypertension (HTN, which may be due to consumption of extra salt (salt as side dish and salted tea at work place and home. The present study evaluated an information, education and communication (IEC module to reduce salt intake and blood pressure among TGW. Methods: Two tea gardens (usual care and intervention were selected at random covering a total population of 13,458. The IEC module consisting of poster display, leaflets, health rally, documentary show, individual and group discussion was introduced in the intervention garden targeting study participants, health care providers, key stake holders, school children and teachers. IEC intervention was continued for one year. Participants from usual care and intervention were followed at three monthly intervals and BP and other information were compared after one year. Results: A total of 393 study participants (Non intervention: 194; intervention: 199 were included. After one year of follow up, consumption of extra salt was reduced significantly in the intervention participants (66.3 vs. 45.5%, p = 0.000. Intention to treat analysis revealed significant reduction in systolic [−6.4 (−8.6 to −4.2] and diastolic [−6.9 (−8.1 to −5.7] blood pressure after one year. Prevalence of HTN was reduced significantly (52.5 vs. 40.0%, p = 0.02 among them. Conclusions: Our IEC module created awareness about risk of hypertension associated with high salt intake and could reduce dietary salt intake and BP. Keywords: Blood pressure, Dietary salt, Hypertension, Tea garden worker

  2. Stand-alone polarization-modulation infrared reflection absorption spectroscopy instrument optimized for the study of catalytic processes at elevated pressures

    Science.gov (United States)

    Kestell, John D.; Mudiyanselage, Kumudu; Ye, Xinyi; Nam, Chang-Yong; Stacchiola, Dario; Sadowski, Jerzy; Boscoboinik, J. Anibal

    2017-10-01

    This paper describes the design and construction of a compact, "user-friendly" polarization-modulation infrared reflection absorption spectroscopy (PM-IRRAS) instrument at the Center for Functional Nanomaterials (CFN) of Brookhaven National Laboratory, which allows studying surfaces at pressures ranging from ultra-high vacuum to 100 Torr. Surface infrared spectroscopy is ideally suited for studying these processes as the vibrational frequencies of the IR chromophores are sensitive to the nature of the bonding environment on the surface. Relying on the surface selection rules, by modulating the polarization of incident light, it is possible to separate the contributions from the isotropic gas or solution phase, from the surface bound species. A spectral frequency range between 1000 cm-1 and 4000 cm-1 can be acquired. While typical spectra with a good signal to noise ratio can be obtained at elevated pressures of gases in ˜2 min at 4 cm-1 resolution, we have also acquired higher resolution spectra at 0.25 cm-1 with longer acquisition times. By way of verification, CO uptake on a heavily oxidized Ru(0001) sample was studied. As part of this test study, the presence of CO adsorbed on Ru bridge sites was confirmed, in agreement with previous ambient pressure X ray photoelectron spectroscopy studies. In terms of instrument performance, it was also determined that the gas phase contribution from CO could be completely removed even up to pressures close to 100 Torr. A second test study demonstrated the use of the technique for studying morphological properties of a spin coated polymer on a conductive surface. Note that this is a novel application of this technique. In this experiment, the polarization of incident light was modulated manually (vs. through a photoelastic modulator). It was demonstrated, in good agreement with the literature, that the polymer chains preferentially lie parallel with the surface. This PM-IRRAS system is small, modular, and easily

  3. Validation of the Serpent 2-DYNSUB code sequence using the Special Power Excursion Reactor Test III (SPERT III)

    International Nuclear Information System (INIS)

    Knebel, Miriam; Mercatali, Luigi; Sanchez, Victor; Stieglitz, Robert; Macian-Juan, Rafael

    2016-01-01

    Highlights: • Full few-group cross section tables created by Monte Carlo lattice code Serpent 2. • Serpent 2 group constant methodology verified for HFP static and transient cases. • Serpent 2-DYNSUB tool chainvalidated using SPERT III REA experiments. • Serpent 2-DYNSUB tool chain suitable to model RIAs in PWRs. - Abstract: The Special Power Excursion Reactor Test III (SPERT III) is studied using the Serpent 2-DYNSUB code sequence in order to validate it for modeling reactivity insertion accidents (RIA) in PWRs. The SPERT III E-core was a thermal research reactor constructed to analyze reactor dynamics. Its configuration resembles a commercial PWR on terms of fuel type, choice of moderator, coolant flow and system pressure. The initial conditions of the rod ejection accident experiments (REA) performed cover cold startup, hot startup, hot standby and operating power scenarios. Eight of these experiments were analyzed in detail. Firstly, multi-dimensional nodal diffusion cross section tables were created for the three-dimensional reactor simulator DYNSUB employing the Monte Carlo neutron transport code Serpent 2. In a second step, DYNSUB stationary simulations were compared to Monte Carlo reference three-dimensional full scale solutions obtained with Serpent 2 (cold startup conditions) and Serpent 2/SUBCHANFLOW (operating power conditions) with a good agreement being observed. The latter tool is an internal coupling of Serpent 2 and the sub-channel thermal-hydraulics code SUBCHANFLOW. Finally, DYNSUB was utilized to study the eight selected transient experiments. Results were found to match measurements well. As the selected experiments cover much of the possible transient (delayed super-critical, prompt super-critical and super-prompt critical excursion) and initial conditions (cold and hot as well as zero, little and full power reactor states) one expects in commercial PWRs, the obtained results give confidence that the Serpent 2-DYNSUB tool chain is

  4. DEVELOPMENT OF PRESSURIZED CIRCULATING FLUIDIZED BED PARTIAL GASIFICATION MODULE (PGM)

    Energy Technology Data Exchange (ETDEWEB)

    Archie Robertson

    2003-10-29

    Foster Wheeler Power Group, Inc. is working under US Department of Energy contract No. DE-FC26-00NT40972 to develop a partial gasification module (PGM) that represents a critical element of several potential coal-fired Vision 21 plants. When utilized for electrical power generation, these plants will operate with efficiencies greater than 60% and produce near zero emissions of traditional stack gas pollutants. The new process partially gasifies coal at elevated pressure producing a coal-derived syngas and a char residue. The syngas can be used to fuel the most advanced power producing equipment such as solid oxide fuel cells or gas turbines, or processed to produce clean liquid fuels or chemicals for industrial users. The char residue is not wasted; it can also be used to generate electricity by fueling boilers that drive the most advanced ultra-supercritical pressure steam turbines. The amount of syngas and char produced by the PGM can be tailored to fit the production objectives of the overall plant, i.e., power generation, clean liquid fuel production, chemicals production, etc. Hence, PGM is a robust building bock that offers all the advantages of coal gasification but in a more user-friendly form; it is also fuel flexible in that it can use alternative fuels such as biomass, sewerage sludge, etc. This report describes the work performed during the July 1--September 30, 2003 time period.

  5. DEVELOPMENT OF PRESSURIZED CIRCULATING FLUIDIZED BED PARTIAL GASIFICATION MODULE (PGM)

    Energy Technology Data Exchange (ETDEWEB)

    Unknown

    2003-01-30

    Foster Wheeler Power Group, Inc. is working under US Department of Energy contract No. DE-FC26-00NT40972 to develop a partial gasification module (PGM) that represents a critical element of several potential coal-fired Vision 21 plants. When utilized for electrical power generation, these plants will operate with efficiencies greater than 60% and produce near zero emissions of traditional stack gas pollutants. The new process partially gasifies coal at elevated pressure producing a coal-derived syngas and a char residue. The syngas can be used to fuel the most advanced power producing equipment such as solid oxide fuel cells or gas turbines, or processed to produce clean liquid fuels or chemicals for industrial users. The char residue is not wasted; it can also be used to generate electricity by fueling boilers that drive the most advanced ultra-supercritical pressure steam turbines. The amount of syngas and char produced by the PGM can be tailored to fit the production objectives of the overall plant, i.e., power generation, clean liquid fuel production, chemicals production, etc. Hence, PGM is a robust building bock that offers all the advantages of coal gasification but in a more user-friendly form; it is also fuel flexible in that it can use alternative fuels such as biomass, sewerage sludge, etc. This report describes the work performed during the October 1--December 31, 2002 time period.

  6. DEVELOPMENT OF PRESSURIZED CIRCULATING FLUIDIZED BED PARTIAL GASIFICATION MODULE (PGM)

    Energy Technology Data Exchange (ETDEWEB)

    Archie Robertson

    2003-07-23

    Foster Wheeler Power Group, Inc. is working under US Department of Energy contract No. DE-FC26-00NT40972 to develop a partial gasification module (PGM) that represents a critical element of several potential coal-fired Vision 21 plants. When utilized for electrical power generation, these plants will operate with efficiencies greater than 60% and produce near zero emissions of traditional stack gas pollutants. The new process partially gasifies coal at elevated pressure producing a coal-derived syngas and a char residue. The syngas can be used to fuel the most advanced power producing equipment such as solid oxide fuel cells or gas turbines, or processed to produce clean liquid fuels or chemicals for industrial users. The char residue is not wasted; it can also be used to generate electricity by fueling boilers that drive the most advanced ultra-supercritical pressure steam turbines. The amount of syngas and char produced by the PGM can be tailored to fit the production objectives of the overall plant, i.e., power generation, clean liquid fuel production, chemicals production, etc. Hence, PGM is a robust building bock that offers all the advantages of coal gasification but in a more user-friendly form; it is also fuel flexible in that it can use alternative fuels such as biomass, sewerage sludge, etc. This report describes the work performed during the April 1--June 30, 2003 time period.

  7. DEVELOPMENT OF PRESSURIZED CIRCULATIONG FLUIDIZED BED PARTIAL GASIFICATION MODULE(PGM)

    Energy Technology Data Exchange (ETDEWEB)

    Archie Robertson

    2003-04-17

    Foster Wheeler Power Group, Inc. is working under US Department of Energy contract No. DE-FC26-00NT40972 to develop a partial gasification module (PGM) that represents a critical element of several potential coal-fired Vision 21 plants. When utilized for electrical power generation, these plants will operate with efficiencies greater than 60% and produce near zero emissions of traditional stack gas pollutants. The new process partially gasifies coal at elevated pressure producing a coal-derived syngas and a char residue. The syngas can be used to fuel the most advanced power producing equipment such as solid oxide fuel cells or gas turbines, or processed to produce clean liquid fuels or chemicals for industrial users. The char residue is not wasted; it can also be used to generate electricity by fueling boilers that drive the most advanced ultra-supercritical pressure steam turbines. The amount of syngas and char produced by the PGM can be tailored to fit the production objectives of the overall plant, i.e., power generation, clean liquid fuel production, chemicals production, etc. Hence, PGM is a robust building block that offers all the advantages of coal gasification but in a more user-friendly form; it is also fuel flexible in that it can use alternative fuels such as biomass, sewerage sludge, etc. This report describes the work performed during the January 1--March 31, 2003 time period.

  8. Development of Pressurized Circulating Fluidized Bed Partial Gasification Module (PGM)

    Energy Technology Data Exchange (ETDEWEB)

    A. Robertson

    2003-12-31

    Foster Wheeler Power Group, Inc. is working under US Department of Energy contract No. DE-FC26-00NT40972 to develop a partial gasification module (PGM) that represents a critical element of several potential coal-fired Vision 21 plants. When utilized for electrical power generation, these plants will operate with efficiencies greater than 60% and produce near zero emissions of traditional stack gas pollutants. The new process partially gasifies coal at elevated pressure producing a coal-derived syngas and a char residue. The syngas can be used to fuel the most advanced power producing equipment such as solid oxide fuel cells or gas turbines, or processed to produce clean liquid fuels or chemicals for industrial users. The char residue is not wasted; it can also be used to generate electricity by fueling boilers that drive the most advanced ultra-supercritical pressure steam turbines. The amount of syngas and char produced by the PGM can be tailored to fit the production objectives of the overall plant, i.e., power generation, clean liquid fuel production, chemicals production, etc. Hence, PGM is a robust building bock that offers all the advantages of coal gasification but in a more user-friendly form; it is also fuel flexible in that it can use alternative fuels such as biomass, sewerage sludge, etc. This report describes the work performed during the October 1 - December 31, 2003 time period.

  9. Phosphotyrosine phosphatase and tyrosine kinase inhibition modulate airway pressure-induced lung injury.

    Science.gov (United States)

    Parker, J C; Ivey, C L; Tucker, A

    1998-11-01

    We determined whether drugs which modulate the state of protein tyrosine phosphorylation could alter the threshold for high airway pressure-induced microvascular injury in isolated perfused rat lungs. Lungs were ventilated for successive 30-min periods with peak inflation pressures (PIP) of 7, 20, 30, and 35 cmH2O followed by measurement of the capillary filtration coefficient (Kfc), a sensitive index of hydraulic conductance. In untreated control lungs, Kfc increased by 1.3- and 3.3-fold relative to baseline (7 cmH2O PIP) after ventilation with 30 and 35 cmH2O PIP. However, in lungs treated with 100 microM phenylarsine oxide (a phosphotyrosine phosphatase inhibitor), Kfc increased by 4.7- and 16.4-fold relative to baseline at these PIP values. In lungs treated with 50 microM genistein (a tyrosine kinase inhibitor), Kfc increased significantly only at 35 cmH2O PIP, and the three groups were significantly different from each other. Thus phosphotyrosine phosphatase inhibition increased the susceptibility of rat lungs to high-PIP injury, and tyrosine kinase inhibition attenuated the injury relative to the high-PIP control lungs.

  10. Shared Responsibility for Type 1 Diabetes Care Is Associated With Glycemic Variability and Risk of Glycemic Excursions in Youth.

    Science.gov (United States)

    Marker, Arwen M; Noser, Amy E; Clements, Mark A; Patton, Susana R

    2018-01-01

    We examined how parent and youth responsibility for type 1 diabetes (T1D) care is related to adherence and glycemic outcomes, namely, glycemic variability and risk of glycemic excursions. One hundred thirty-five parent-youth dyads (10-16 years old; diagnosed with T1D for at least 6 months) participated in this study. Percent responsibility of T1D care attributed to the youth, parent, or shared was measured using the Diabetes Family Responsibility Questionnaire. We collected youth's hemoglobin A1c (HbA1c) and glucometer downloads to examine relationships between responsibility and HbA1c, frequency of blood glucose monitoring (self-monitoring blood glucose, SMBG), risk of glycemic excursions, and actual glycemic variability using bivariate correlations and path analysis. Participants reported shared responsibility for almost half of T1D self-care tasks. Bivariate correlations showed shared responsibility was associated with less variability, whereas parent responsibility was associated with greater glycemic variability and risk for glycemic excursions. Youth responsibility was associated with lower frequency of SMBG. The path analyses confirmed our correlational findings (pshypothesis that shared T1D responsibility is associated with better diabetes outcomes in youth. © The Author 2017. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  11. Doppler ultrasound surveillance in deep tunneling compressed-air work with Trimix breathing: bounce dive technique compared to saturation-excursion technique.

    Science.gov (United States)

    Vellinga, T P van Rees; Sterk, W; de Boer, A G E M; van der Beek, A J; Verhoeven, A C; van Dijk, F J H

    2008-01-01

    The Western Scheldt Tunneling Project in The Netherlands provided a unique opportunity to evaluate two deep-diving techniques with Doppler ultrasound surveillance. Divers used the bounce diving techniques for repair and maintenance of the TBM. The tunnel boring machine jammed at its deepest depth. As a result the work time was not sufficient. The saturation diving technique was developed and permitted longer work time at great depth. Thirty-one divers were involved in this project. Twenty-three divers were examined using Doppler ultrasound. Data analysis addressed 52 exposures to Trimix at 4.6-4.8 bar gauge using the bounce technique and 354 exposures to Trimix at 4.0-6.9 bar gauge on saturation excursions. No decompression incidents occurred with either technique during the described phase of the project. Doppler ultrasound revealed that the bubble loads assessed in both techniques were generally low. We find out, that despite longer working hours, shorter decompression times and larger physical workloads, the saturation-excursion technique was associated with significant lower bubble grades than in the bounce technique using Doppler Ultrasound. We conclude that the saturation-excursion technique with Trimix is a good option for deep and long exposures in caisson work. The Doppler technique proved valuable, and it should be incorporated in future compressed-air work.

  12. Creep Burst Testing of a Woven Inflatable Module

    Science.gov (United States)

    Selig, Molly M.; Valle, Gerard D.; James, George H.; Oliveras, Ovidio M.; Jones, Thomas C.; Doggett, William R.

    2015-01-01

    A woven Vectran inflatable module 88 inches in diameter and 10 feet long was tested at the NASA Johnson Space Center until failure from creep. The module was pressurized pneumatically to an internal pressure of 145 psig, and was held at pressure until burst. The external environment remained at standard atmospheric temperature and pressure. The module burst occurred after 49 minutes at the target pressure. The test article pressure and temperature were monitored, and video footage of the burst was captured at 60 FPS. Photogrammetry was used to obtain strain measurements of some of the webbing. Accelerometers on the test article measured the dynamic response. This paper discusses the test article, test setup, predictions, observations, photogrammetry technique and strain results, structural dynamics methods and quick-look results, and a comparison of the module level creep behavior to the strap level creep behavior.

  13. Development of 10kW SOFC module

    Energy Technology Data Exchange (ETDEWEB)

    Hisatome, N.; Nagata, K. [Mitsubishi Heavy Industries, Ltd., Nagasaki (Japan); Kakigami, S. [Electric Power Development Co., Inc., Tokyo (Japan)] [and others

    1996-12-31

    Mitsubishi Heavy industries, Ltd. (MHI) has been developing tubular type Solid Oxide Fuel Cells (SOFC) since 1984. A 1 kW module of SOFC has been continuously operated for 3,000 hours with 2 scheduled thermal cycles at Electric Power Development Co., Inc. (EPDC) Wakamatsu Power Station in 1993. We have obtained of 34% (HHV as H{sub 2}) module efficiency and deterioration rate of 2% Per 1,000 hours in this field test. As for next step, we have developed 10 kW module in 1995. The 10 kW module has been operated for 5,000 hours continuously. This module does not need heating support to maintain the operation temperature, and the module efficiency was 34% (HHV as H{sub 2}). On the other hand, we have started developing the technology of pressurized SOFC. In 1996, pressurized MW module has been tested at MHI Nagasaki Shipyard & Machinery, Works. We are now planning the development of pressurized 10 kW module.

  14. The main problems of Cycling excursions on the Moscow market

    Directory of Open Access Journals (Sweden)

    Sergeev A.A.

    2016-12-01

    Full Text Available the article discusses the reasons of rejection of Bicycle transport. It is noted that the main causes are the heavy ecological situation in Moscow and a large number of vehicles. The authors note that according to the Department of natural resources 90% of pollution is caused by the road transport. To solve this problem, the authors offer to use bicycles and to develop a network of cycle routes and excursions, improve the quality of bike paths to connect them together, to approve the rules of the road (SDA for cyclists, which will reduce the number of accidents with their participation. The article presents strong arguments in favor of the development and use of bicycles and bicycle tours.

  15. The museum “La casa encantada” of Briones in the teaching of history: proposed primary education school excursion

    Directory of Open Access Journals (Sweden)

    Sebastián Molina Puche

    2013-05-01

    Full Text Available It has been demonstrated, in order that the school excursions develop all his didactic potential (this is, in order that they serve to stimulate the “guided discovery” learning, have to be framed in didactic itineraries and with it, to be considered as an integral part of the didactic programming of the course. The curricular integration of the school excursions is one of the principal problems which the teacher meets at the moment of putting in practical this important didactic resource. With this work we claim, beside showing many possibilities that there has the museum of “The Enchanted House” of Briones (section ethnology of the Museum of La Rioja for the learning of the history in Primary Education, to indicate how they can integrate in the curriculum the visits to the museum in each of three cycles that shape this educational level.

  16. UK regulatory aspects of prestressed concrete pressure vessels for gas-cooled reactor nuclear power stations

    International Nuclear Information System (INIS)

    Watson, P.S.

    1990-01-01

    Safety assessment principles for nuclear power plants and for nuclear chemical plants demand application of best proven techniques, recognised standards, adequacy margins, inspection and maintenance of all the components including prestressed concrete pressure vessels. In service inspection of prestressed concrete pressure vessels includes: concrete surface examination; anchorage inspection; tendon load check; tendon material examination; foundation settlement and tilt; log-term deformation; vessel temperature excursions; coolant loss; top cap deflection. Hartlepool and Heysham 1 power plants prestress shortfall problem is discussed. Main recommendations can be summarised as follows: at all pressure vessel stations prestress systems should be calibrated in a manner which results in all load bearing components being loaded in a representative manner; at all pressure vessel stations load measurements during calibration should be verified by a redundant and diverse system

  17. Estimates of the effectiveness of automatic control in alleviating wake vortex induced roll excursions

    Science.gov (United States)

    Tinling, B. E.

    1977-01-01

    Estimates of the effectiveness of a model following type control system in reducing the roll excursion due to a wake vortex encounter were obtained from single degree of freedom computations with inputs derived from the results of wind tunnel, flight, and simulation experiments. The analysis indicates that the control power commanded by the automatic system must be roughly equal to the vortex induced roll acceleration if effective limiting of the maximum bank angle is to be achieved.

  18. Optimization of vehicle weight for Mars excursion missions

    Science.gov (United States)

    Ferebee, Melvin J., Jr.

    1991-01-01

    The excursion class mission to Mars is defined as a mission with one year durations coupled with a stay time of up to 30 days. The fuel budget for such a mission is investigated. The overall figure of merit in such an assessment is the vehicle weight ratio, the ratio between the wet vehicle weight to the dry vehicle weight. It is necessary to minimize the overall fuel budget for the mission in order to maximize the benefits that could be obtained by sending humans to Mars. Assumptions used in the analysis are: each mission will depart and terminate in low-earth-orbit (LEO) (500 km circular) and the maximum stay time at Mars is 30 days. The maximum mission duration is one year (355-375 days). The mass returned to LEO is 135,000 kg, the dropoff mass left at Mars is 168,000 kg. Three propulsive techniques for atmospheric interface are investigated: aerobraking, all-chemical propulsion, and nuclear thermal propulsion. By defining the fuel requirements, the space transfer vehicle's configuration is defined.

  19. Exercise training prevents increased intraocular pressure and sympathetic vascular modulation in an experimental model of metabolic syndrome

    International Nuclear Information System (INIS)

    Castro, E.F.S.; Mostarda, C.T.; Rodrigues, B.; Moraes-Silva, I.C.; Feriani, D.J.; De Angelis, K.; Irigoyen, M.C.

    2015-01-01

    The present study aimed to study the effects of exercise training (ET) performed by rats on a 10-week high-fructose diet on metabolic, hemodynamic, and autonomic changes, as well as intraocular pressure (IOP). Male Wistar rats receiving fructose overload in drinking water (100 g/L) were concomitantly trained on a treadmill for 10 weeks (FT group) or kept sedentary (F group), and a control group (C) was kept in normal laboratory conditions. The metabolic evaluation comprised the Lee index, glycemia, and insulin tolerance test (KITT). Arterial pressure (AP) was measured directly, and systolic AP variability was performed to determine peripheral autonomic modulation. ET attenuated impaired metabolic parameters, AP, IOP, and ocular perfusion pressure (OPP) induced by fructose overload (FT vs F). The increase in peripheral sympathetic modulation in F rats, demonstrated by systolic AP variance and low frequency (LF) band (F: 37±2, 6.6±0.3 vs C: 26±3, 3.6±0.5 mmHg 2 ), was prevented by ET (FT: 29±3, 3.4±0.7 mmHg 2 ). Positive correlations were found between the LF band and right IOP (r=0.57, P=0.01) and left IOP (r=0.64, P=0.003). Negative correlations were noted between KITT values and right IOP (r=-0.55, P=0.01) and left IOP (r=-0.62, P=0.005). ET in rats effectively prevented metabolic abnormalities and AP and IOP increases promoted by a high-fructose diet. In addition, ocular benefits triggered by exercise training were associated with peripheral autonomic improvement

  20. Gas Hydrate-Sediment Morphologies Revealed by Pressure Core Analysis

    Science.gov (United States)

    Holland, M.; Schultheiss, P.; Roberts, J.; Druce, M.

    2006-12-01

    Analysis of HYACINTH pressure cores collected on IODP Expedition 311 and NGHP Expedition 1 showed gas hydrate layers, lenses, and veins contained in fine-grained sediments as well as gas hydrate contained in coarse-grained layers. Pressure cores were recovered from sediments on the Cascadia Margin off the North American West Coast and in the Krishna-Godavari Basin in the Western Bay of Bengal in water depths of 800- 1400 meters. Recovered cores were transferred to laboratory chambers without loss of pressure and nondestructive measurements were made at in situ pressures and controlled temperatures. Gamma density, P-wave velocity, and X-ray images showed evidence of grain-displacing and pore-filling gas hydrate in the cores. Data highlights include X-ray images of fine-grained sediment cores showing wispy subvertical veins of gas hydrate and P-wave velocity excursions corresponding to grain-displacing layers and pore-filling layers of gas hydrate. Most cores were subjected to controlled depressurization experiments, where expelled gas was collected, analyzed for composition, and used to calculate gas hydrate saturation within the core. Selected cores were stored under pressure for postcruise analysis and subsampling.

  1. ULF Generation by Modulated Ionospheric Heating

    Science.gov (United States)

    Chang, C.; Labenski, J.; Wallace, T.; Papadopoulos, K.

    2013-12-01

    Modulated ionospheric heating experiments designed to generate ULF waves using the HAARP heater have been conducted since 2007. Artificial ULF waves in the Pc1 frequency range were observed from space and by ground induction magnetometers located in the vicinity of the heater as well as at long distances. Two distinct generation mechanisms of artificial ULF waves were identified. The first was electroject modulation under geomagnetically disturbed conditions. The second was pressure modulation in the E and F regions of the ionosphere under quiet conditions. Ground detections of ULF waves near the heater included both Shear Alfven waves and Magnetosonic waves generated by electrojet and/or pressure modulations. Distant ULF detections involved Magnetosonic wave propagation in the Alfvenic duct with pressure modulation as the most likely source. Summary of our observations and theoretical interpretations will be presented at the meeting. We would like to acknowledge the support provided by the staff at the HAARP facility during our ULF experiments.

  2. Perception of a Sung Vowel as a Function of Frequency-Modulation Rate and Excursionin Normal-Hearing and Hearing-Impaired Listeners

    DEFF Research Database (Denmark)

    Vatti, Marianna; Santurette, Sébastien; Pontoppidan, Niels henrik

    2014-01-01

    Purpose: Frequency fluctuations in human voices can usually be described as coherent frequency modulation (FM). As listeners with hearing impairment (HI listeners) are typically less sensitive to FM than listeners with normal hearing (NH listeners), this study investigated whether hearing loss...... affects the perception of a sung vowel based on FM cues. Method: Vibrato maps were obtained in 14 NH and 12 HI listeners with different degrees of musical experience. The FM rate and FM excursion of a synthesized vowel, to which coherent FM was applied, were adjusted until a singing voice emerged. Results......: In NH listeners, adding FM to the steady vowel components produced perception of a singing voice for FM rates between 4.1 and 7.5 Hz and FM excursions between 17 and 83 cents on average. In contrast, HI listeners showed substantially broader vibrato maps. Individual differences in map boundaries were...

  3. Morphology of the Iceland Basin Excursion from a spherical harmonics analysis and an iterative Bayesian inversion procedure of sedimentary records

    Science.gov (United States)

    Lanci, Luca; Kissel, Catherine; Leonhardt, Roman; Laj, Carlo

    2008-08-01

    Based on 5 published marine high-resolution sedimentary records of the Iceland Basin Excursion [IBE; Channell, J.E.T., Hodell, D.A., Lehman, B., 1997. Relative geomagnetic paleointensity and ∂ 18O at ODP Site 983/Gardar Drift, North Atlantic since 350 ka. Earth Planet. Sci. Lett. 153, 103-118; Laj, C., Kissel, C., Roberts, A., 2006. Geomagnetic field behavior during the Iceland Basin and Laschamp geomagnetic excursions: a simple transitional field geometry? Geochem. Geophys. Geosystems. 7, Q03004, doi:10.1029/2005GC001122] dated around 186-190 kyr, we present models of the excursional geomagnetic field at the Earth's surface using two different approaches. First a spherical harmonics analysis is performed after synchronization of the records using their paleointensity profiles. Second, we have used an iterative Bayesian inversion procedure, calibrated using the single volcanic data available so far. Both modeling approaches suffer from imperfections of the paleomagnetic signals and mostly from the still poor geographical distribution of detailed records, presently available only from the North Atlantic and the West Pacific. For these reasons, our modeling results should only be regarded as preliminary models of the geomagnetic field during the IBE, susceptible to improvements when including results from future paleomagnetic studies. Nevertheless, both approaches show distinct similarities and are stable against moderate variations of modeling parameters. The general picture is that of a dipole field undergoing a strong reduction, but remaining higher than the non-dipole field all through the excursional process, except for a very short interval of time corresponding to the dipole minimum at the center of the excursion. On the other hand, some differences exist between the results of the two models with each other and with the real data when the virtual geomagnetic pole (VGP) paths are considered. The non-dipole field does not appear to undergo very significant

  4. Proofs of the Cantor-Bernstein theorem a mathematical excursion

    CERN Document Server

    Hinkis, Arie

    2013-01-01

    This book offers an excursion through the developmental area of research mathematics. It presents some 40 papers, published between the 1870s and the 1970s, on proofs of the Cantor-Bernstein theorem and the related Bernstein division theorem. While the emphasis is placed on providing accurate proofs, similar to the originals, the discussion is broadened to include aspects that pertain to the methodology of the development of mathematics and to the philosophy of mathematics. Works of prominent mathematicians and logicians are reviewed, including Cantor, Dedekind, Schröder, Bernstein, Borel, Zermelo, Poincaré, Russell, Peano, the Königs, Hausdorff, Sierpinski, Tarski, Banach, Brouwer and several others mainly of the Polish and the Dutch schools. In its attempt to present a diachronic narrative of one mathematical topic, the book resembles Lakatos’ celebrated book Proofs and Refutations. Indeed, some of the observations made by Lakatos are corroborated herein. The analogy between the two books is clearly an...

  5. Effect of hamstring flexibility on hip and lumbar spine joint excursions during forward-reaching tasks in participants with and without low back pain.

    Science.gov (United States)

    Johnson, Erica N; Thomas, James S

    2010-07-01

    To examine the correlation between hamstring flexibility and hip and lumbar spine joint excursions during standardized reaching and forward-bending tasks. Retrospective analysis of data obtained during 2 previous prospective studies that examined kinematics and kinetics during forward-reaching tasks in participants with and without low back pain (LBP). The 2 previous studies were conducted in the Motor Control Lab at Ohio University and the Orthopaedic Ergonomics Laboratory at The Ohio State University. Data from a total of 122 subjects from 2 previous studies: study 1: 86 subjects recovered from an episode of acute LBP (recovered) and study 2 (A.I. McCallum, unpublished data): 18 chronic LBP subjects and 18 healthy-matched controls (healthy). Not applicable. Correlation values between hamstring flexibility as measured by straight leg raise (SLR) and amount of hip and lumbar spine joint excursions used during standardized reaching and forward-bending tasks. No significant correlation was found between hamstring flexibility and hip and lumbar joint excursions during forward-bending tasks in the LBP or recovered groups. The SLR had a significant negative correlation with lumbar spine excursions during reaching tasks to a low target in the healthy group (right SLR: P=.011, left SLR: P=.004). Hamstring flexibility is not strongly related to the amount of lumbar flexion used to perform forward-reaching tasks in participants who have chronic LBP or who have recovered from LBP. More research needs to be conducted to examine the influence of hamstring flexibility on observed movement patterns to further evaluate the efficacy of flexibility training in the rehabilitation of patients with LBP. Copyright 2010 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  6. Glucose and triglyceride excursions following a standardized meal in individuals with diabetes: ELSA-Brasil study

    OpenAIRE

    Riboldi, B?rbara P; Luft, Vivian C; de Castilhos, Cristina D; de Cardoso, Let?cia O; Schmidt, Maria I; Barreto, Sandhi M; de Sander, Maria F; Alvim, Sheila M; Duncan, Bruce B

    2015-01-01

    Objective: To assess glucose and triglyceride excursions 2 hours after the ingestion of a standardized meal and their associations with clinical characteristics and cardiovascular complications in individuals with diabetes. Research design and methods: Blood samples of 898 subjects with diabetes were collected at fasting and 2 hours after a meal containing 455 kcal, 14 g of saturated fat and 47 g of carbohydrates. Self-reported morbidity, socio-demographic characteristics and clinical measure...

  7. Star Excursion Balance Test Anterior Asymmetry Is Associated With Injury Status in Division I Collegiate Athletes.

    Science.gov (United States)

    Stiffler, Mikel R; Bell, David R; Sanfilippo, Jennifer L; Hetzel, Scott J; Pickett, Kristen A; Heiderscheit, Bryan C

    2017-05-01

    Study Design Retrospective cohort. Background Star Excursion Balance Test (SEBT) performance differs by sport in healthy collegiate athletes, and lower extremity injury rates also vary by sport, sex, and athletic exposure. The relationship between SEBT performance and injury risk has not been evaluated with consideration of these additional variables, which may be necessary to fully describe the relationship between SEBT performance and injury risk. Objectives To assess the association between preseason SEBT performance and noncontact injury occurrence to the knee or ankle in Division I collegiate athletes when controlling for sport, sex, and athletic exposure. Methods Star Excursion Balance Test performance, starting status, and injury status were reviewed retrospectively in National Collegiate Athletic Association Division I collegiate athletes from a single institution. A total of 147 athletes were healthy at the time of preseason SEBT testing and either remained healthy (n = 118) or sustained a noncontact injury to the knee or ankle (n = 29) during their sport's subsequent competitive season. Side-to-side asymmetries were calculated in each direction as the absolute difference in reach distance between limbs. Star Excursion Balance Test reach distances and asymmetries were compared between groups using multivariable regression, controlling for sport, sex, and athletic exposure (starter, nonstarter). Receiver operating characteristic curves were used to determine optimal sensitivity and specificity for significant models. Results When controlling for sport, sex, and athletic exposure, SEBT side-to-side asymmetry in the anterior direction, expressed as an absolute or normalized to limb length, discriminated between injured and noninjured athletes (area under the curve greater than 0.82). Conclusion Assessing side-to-side reach asymmetry in the anterior direction of the SEBT may assist in identifying collegiate athletes who are at risk for sustaining noncontact

  8. Conditioned Pain Modulation and Pressure Pain Sensitivity in the Adult Danish General Population: The DanFunD Study

    DEFF Research Database (Denmark)

    Skovbjerg, Sine; Jørgensen, Torben; Arendt-Nielsen, Lars

    2017-01-01

    with cold pressor pain (hand) for 2 minutes. Conditioning pain intensity was assessed using a visual analog scale and questionnaire data were collected. Female sex (P stress......Increased pressure pain sensitivity and impaired descending pain control have been associated with chronic pain, but knowledge on the variability in the adult general population is lacking. Pressure pain thresholds (PPTs) and descending pain control assessed using conditioned pain modulation (CPM...... (P ≤ .02), and high visual analog scale score (P ≤ .02) were associated with a larger CPM response. PERSPECTIVE: Data from this large population-based study provide new insight into the gender and age variation in pain sensitivity and CPM response. Decreased CPM potency and increased pain sensitivity...

  9. Exercise training prevents increased intraocular pressure and sympathetic vascular modulation in an experimental model of metabolic syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Castro, E.F.S. [Unidade de Hipertensão, Instituto do Coração, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP (Brazil); Mostarda, C.T. [Universidade Federal do Maranhão, São Luís, MA (Brazil); Rodrigues, B. [Laboratório do Movimento Humano, Universidade São Judas Tadeu, São Paulo, SP (Brazil); Moraes-Silva, I.C. [Unidade de Hipertensão, Instituto do Coração, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP (Brazil); Feriani, D.J. [Laboratório do Movimento Humano, Universidade São Judas Tadeu, São Paulo, SP (Brazil); De Angelis, K. [Laboratório de Fisiologia Translacional, Universidade Nove de Julho, São Paulo, SP (Brazil); Irigoyen, M.C. [Unidade de Hipertensão, Instituto do Coração, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP (Brazil)

    2015-02-13

    The present study aimed to study the effects of exercise training (ET) performed by rats on a 10-week high-fructose diet on metabolic, hemodynamic, and autonomic changes, as well as intraocular pressure (IOP). Male Wistar rats receiving fructose overload in drinking water (100 g/L) were concomitantly trained on a treadmill for 10 weeks (FT group) or kept sedentary (F group), and a control group (C) was kept in normal laboratory conditions. The metabolic evaluation comprised the Lee index, glycemia, and insulin tolerance test (KITT). Arterial pressure (AP) was measured directly, and systolic AP variability was performed to determine peripheral autonomic modulation. ET attenuated impaired metabolic parameters, AP, IOP, and ocular perfusion pressure (OPP) induced by fructose overload (FT vs F). The increase in peripheral sympathetic modulation in F rats, demonstrated by systolic AP variance and low frequency (LF) band (F: 37±2, 6.6±0.3 vs C: 26±3, 3.6±0.5 mmHg{sup 2}), was prevented by ET (FT: 29±3, 3.4±0.7 mmHg{sup 2}). Positive correlations were found between the LF band and right IOP (r=0.57, P=0.01) and left IOP (r=0.64, P=0.003). Negative correlations were noted between KITT values and right IOP (r=-0.55, P=0.01) and left IOP (r=-0.62, P=0.005). ET in rats effectively prevented metabolic abnormalities and AP and IOP increases promoted by a high-fructose diet. In addition, ocular benefits triggered by exercise training were associated with peripheral autonomic improvement.

  10. The use of genetic programming to develop a predictor of swash excursion on sandy beaches

    OpenAIRE

    M. Passarella; E. B. Goldstein; S. De Muro; G. Coco

    2018-01-01

    We use genetic programming (GP), a type of machine learning (ML) approach, to predict the total and infragravity swash excursion using previously published data sets that have been used extensively in swash prediction studies. Three previously published works with a range of new conditions are added to this data set to extend the range of measured swash conditions. Using this newly compiled data set we demonstrate that a ML approach can reduce the prediction errors compared ...

  11. Feasibility of a fast optical pressure interlock for the ITER neutral beam injectors

    International Nuclear Information System (INIS)

    Ash, Andrew; Surrey, Elizabeth

    2009-01-01

    The feasibility of using Balmer-α emission for a high-speed pressure diagnostic and beam interlock for the ITER neutral beam heating system is investigated. An interlock is needed to prevent excessive re-ionisation of the neutral beam when rapid excursions of pressure occur in either the electrostatic residual ion dump (ERID), or the neutral beam duct (NBD). The re-ionised fraction of the beam, will be deflected by stray tokamak fields, potentially causing excessive thermal loads on beam line components. Experience from JET indicates that a response time of order 100 μs is required in order to prevent fast pressure excursions. Fast penning gauges have a time response of around 30-50 ms, however, a faster response (around 1 μs) is possible by monitoring the H α (656.3 nm)/D α (656.1 nm) emission from collisional excitation of the background gas and neutral beam. Published total cross-sections are used to calculate a signal of 3.5x10 13 -3.0x10 17 photons s -1 m -2 sr -1 for normal conditions. This signal must be distinguished from the background light of the tokamak plasma (line emission and bremsstrahlung). The beam emission is Doppler shifted by up to 21 nm (D operation) and up to 27 nm (H operation) depending on angle of observation and this can be used to help distinguish against background line emission. The distribution of background light along the beam line is calculated with a two-dimensional radiosity code, solving the equilibrium energy balance within the beam line enclosure. The Balmer-α signal and background signal due to bremsstrahlung are compared for a 500-MW reference plasma.

  12. Diode Laser Detection of Greenhouse Gases in the Near-Infrared Region by Wavelength Modulation Spectroscopy: Pressure Dependence of the Detection Sensitivity

    Directory of Open Access Journals (Sweden)

    Takashi Asakawa

    2010-05-01

    Full Text Available We have investigated the pressure dependence of the detection sensitivity of CO2, N2O and CH4 using wavelength modulation spectroscopy (WMS with distributed feed-back diode lasers in the near infrared region. The spectral line shapes and the background noise of the second harmonics (2f detection of the WMS were analyzed theoretically. We determined the optimum pressure conditions in the detection of CO2, N2O and CH4, by taking into consideration the background noise in the WMS. At the optimum total pressure for the detection of CO2, N2O and CH4, the limits of detection in the present system were determined.

  13. Graft-to-recipient weight ratio lower to 0.7% is safe without portal pressure modulation in right-lobe living donor liver transplantation with favorable conditions.

    Science.gov (United States)

    Lee, Seung Duk; Kim, Seong Hoon; Kim, Young-Kyu; Lee, Soon-Ae; Park, Sang-Jae

    2014-02-01

    The low graft-to-recipient weight ratio (GRWR) in adult-to-adult living donor liver transplantation (LDLT) is one of the major risk factors affecting graft survival. The goal of this study was to evaluate whether the lower limit of the GRWR can be safely reduced without portal pressure modulation in right-lobe LDLT. From 2005 to 2011, 317 consecutive patients from a single institute underwent LDLT with right-lobe grafts without portal pressure modulation. Of these, 23 had a GRWR of less than 0.7% (group A), 27 had a GRWR of ≥0.7%, recipient, donor, operation factors, laboratory findings and complications were reviewed retrospectively. The baseline demographics showed low model for end-stage liver disease score (mean 16.3+/-8.9) and high percentage of hepatocellular carcinoma (231 patients, 72.9%). Three groups by GRWR demonstrated similar characteristics except recipient body mass index and donor gender. For small-for-size syndrome, there were 3 (13.0%) in group A, 1 (3.7%) in group B, and 2 patients (0.7%) in group C (Pneed to modulate portal pressure in adult-to-adult LDLT using the right-lobe in favorable conditions including low model for end-stage liver disease score.

  14. The impact of animation on the length of stay and radius of movement of the excursion-recreational tourism

    Directory of Open Access Journals (Sweden)

    Dimitrić Dragana

    2016-01-01

    Full Text Available The basic hypothesis from which we started in the paper is the claim that animation of visitors has a direct impact on the length and radius of excursion-recreational tourism. The main objective of the research is to define the role of animation in the choice of tourist destination and length of staying. In the area of the City of Belgrade, there are more protected natural areas and one of them is the Great War Island located at the confluence of the River Sava in River Danube. This area has three protected zones. Temporary population that was the subject of the interview, as well as the Association of Tourist Guides of Serbia occupate one of these zones. We concluded that one of the biggest advantages of developing tourism of the Great War Island is the possibility of developing certain forms of tourism, and one of these forms, the excursion-recreational tourism has multiple positive effects on the population. The paper concluded that the animation proportionally affects the length of stay of tourists, as well as the radius of their movement.

  15. Kilovoltage Intrafraction Monitoring for Prostate Intensity Modulated Arc Therapy: First Clinical Results

    International Nuclear Information System (INIS)

    Ng, Jin Aun; Booth, Jeremy T.; Poulsen, Per R.; Fledelius, Walther; Worm, Esben Schjødt; Eade, Thomas; Hegi, Fiona; Kneebone, Andrew; Kuncic, Zdenka; Keall, Paul J.

    2012-01-01

    Purpose: Most linear accelerators purchased today are equipped with a gantry-mounted kilovoltage X-ray imager which is typically used for patient imaging prior to therapy. A novel application of the X-ray system is kilovoltage intrafraction monitoring (KIM), in which the 3-dimensional (3D) tumor position is determined during treatment. In this paper, we report on the first use of KIM in a prospective clinical study of prostate cancer patients undergoing intensity modulated arc therapy (IMAT). Methods and Materials: Ten prostate cancer patients with implanted fiducial markers undergoing conventionally fractionated IMAT (RapidArc) were enrolled in an ethics-approved study of KIM. KIM involves acquiring kV images as the gantry rotates around the patient during treatment. Post-treatment, markers in these images were segmented to obtain 2D positions. From the 2D positions, a maximum likelihood estimation of a probability density function was used to obtain 3D prostate trajectories. The trajectories were analyzed to determine the motion type and the percentage of time the prostate was displaced ≥3, 5, 7, and 10 mm. Independent verification of KIM positional accuracy was performed using kV/MV triangulation. Results: KIM was performed for 268 fractions. Various prostate trajectories were observed (ie, continuous target drift, transient excursion, stable target position, persistent excursion, high-frequency excursions, and erratic behavior). For all patients, 3D displacements of ≥3, 5, 7, and 10 mm were observed 5.6%, 2.2%, 0.7% and 0.4% of the time, respectively. The average systematic accuracy of KIM was measured at 0.46 mm. Conclusions: KIM for prostate IMAT was successfully implemented clinically for the first time. Key advantages of this method are (1) submillimeter accuracy, (2) widespread applicability, and (3) a low barrier to clinical implementation. A disadvantage is that KIM delivers additional imaging dose to the patient.

  16. Accidental nuclear excursion Recuplex operation 234-5 facility. Final report: Date of incident: April 7, 1962

    Energy Technology Data Exchange (ETDEWEB)

    1962-08-01

    On Saturday morning, April 7, 1962, at about 1059 Armed Forces time, an accidental nuclear excursion occurred in the plutonium waste recovery facility (Recuplex) of the 234-5 Building. This excursion did not result in any mechanical damage or spread of contamination. Three employees of the General Electric Company received overexposures to gamma and neutron radiation. None were fatally exposed; in each case the overexposure was recognized promptly, and following medical observation and testing the men were released to return to work. In compliance with AEC Manual Chapter 0703, an AEC-HAPO committee composed of two AEC employees and five General Electric employees was appointed by the Manger, HOO, with the concurrence of the General Manager, HAPO, to conduct an investigation of the incident. The committee`s purpose was to determine the cause, nature, and extent of the incident, and recommend action to be taken by others to minimize or preclude future incidents of this magnitude. A study of operating practices and operating conditions that appeared to exist prior to, during, and subsequent to the accident was made by the committee. The committee believes that this report provides sufficient information to answer questions which may arise as a result of the criticality incident except those relating to its cause.

  17. A new approach of the Star Excursion Balance Test to assess dynamic postural control in people complaining from chronic ankle instability.

    Science.gov (United States)

    Pionnier, Raphaël; Découfour, Nicolas; Barbier, Franck; Popineau, Christophe; Simoneau-Buessinger, Emilie

    2016-03-01

    The purpose of this study was to quantitatively and qualitatively assess dynamic balance with accuracy in individuals with chronic ankle instability (CAI). To this aim, a motion capture system was used while participants performed the Star Excursion Balance Test (SEBT). Reached distances for the 8 points of the star were automatically computed, thereby excluding any dependence to the experimenter. In addition, new relevant variables were also computed, such as absolute time needed to reach each distance, lower limb ranges of motion during unipodal stance, as well as absolute error of pointing. Velocity of the center of pressure and range of variation of ground reaction forces have also been assessed during the unipodal phase of the SEBT thanks to force plates. CAI group exhibited smaller reached distances and greater absolute error of pointing than the control group (p<0.05). Moreover, the ranges of motion of lower limbs joints, the velocity of the center of pressure and the range of variation of the ground reaction forces were all significantly smaller in the CAI group (p<0.05). These reduced quantitative and qualitative performances highlighted a lower dynamic postural control. The limited body movements and accelerations during the unipodal stance in the CAI group could highlight a protective strategy. The present findings could help clinicians to better understand the motor strategies used by CAI patients during dynamic balance and may guide the rehabilitation process. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. Students' Long-Term Memories from an Ecology Field Excursion: Retelling a Narrative as an Interplay between Implicit and Explicit Memories

    Science.gov (United States)

    Stolpe, Karin; Bjorklund, Lars

    2013-01-01

    This study aims to investigate the science content remembered by biology students 6 and 12 months after an ecology excursion. The students' memories were tested during a stimulated recall interview. The authors identified three different types of memories: "recall," "recognition" and "narratives." The "dual…

  19. System for detecting operating errors in a variable valve timing engine using pressure sensors

    Science.gov (United States)

    Wiles, Matthew A.; Marriot, Craig D

    2013-07-02

    A method and control module includes a pressure sensor data comparison module that compares measured pressure volume signal segments to ideal pressure volume segments. A valve actuation hardware remedy module performs a hardware remedy in response to comparing the measured pressure volume signal segments to the ideal pressure volume segments when a valve actuation hardware failure is detected.

  20. The impact of round window vs cochleostomy surgical approaches on interscalar excursions in the cochlea: Preliminary results from a flat-panel computed tomography study

    Directory of Open Access Journals (Sweden)

    Nicole T. Jiam

    2016-09-01

    Full Text Available Objective: To evaluate incidence of interscalar excursions between round window (RW and cochleostomy approaches for cochlear implant (CI insertion. Methods: This was a retrospective case-comparison. Flat-panel CT (FPCT scans for 8 CI users with Med-El standard length electrode arrays were collected. Surgical technique was identified by a combination of operative notes and FPCT imaging. Four cochleae underwent round window insertion and 4 cochleae underwent cochleostomy approaches anterior and inferior to the round window. Results: In our pilot study, cochleostomy approaches were associated with a higher likelihood of interscalar excursion. Within the cochleostomy group, we found 29% of electrode contacts (14 of 48 electrodes to be outside the scala tympani. On the other hand, 8.5% of the electrode contacts (4 of 47 electrodes in the round window insertion group were extra-scalar to the scala tympani. These displacements occurred at a mean angle of occurrence of 364° ± 133°, near the apex of the cochlea. Round window electrode displacements tend to localize at angle of occurrences of 400° or greater. Cochleostomy electrodes occurred at an angle of occurrence of 19°–490°. Conclusions: Currently, the optimal surgical approach for standard CI electrode insertion is highly debated, to a certain extent due to a lack of post-operative assessment of intracochlear electrode contact. Based on our preliminary findings, cochleostomy approach is associated with an increased likelihood of interscalar excursions, and these findings should be further evaluated with future prospective studies. Keywords: Cochlear implantation, Round window insertion, Cochleostomy, Interscalar excursion, Electrode position, Flat-panel computed tomography, Surgical approach

  1. Excursions out-of-lane versus standard deviation of lateral position as outcome measure of the on-the-road driving test

    NARCIS (Netherlands)

    Verster, Joris C; Roth, Thomas

    BACKGROUND: The traditional outcome measure of the Dutch on-the-road driving test is the standard deviation of lateral position (SDLP), the weaving of the car. This paper explores whether excursions out-of-lane are a suitable additional outcome measure to index driving impairment. METHODS: A

  2. The Role of Arch Compression and Metatarsophalangeal Joint Dynamics in Modulating Plantar Fascia Strain in Running

    Science.gov (United States)

    McDonald, Kirsty A.; Stearne, Sarah M.; Alderson, Jacqueline A.; North, Ian; Pires, Neville J.; Rubenson, Jonas

    2016-01-01

    Elastic energy returned from passive-elastic structures of the lower limb is fundamental in lowering the mechanical demand on muscles during running. The purpose of this study was to investigate the two length-modulating mechanisms of the plantar fascia, namely medial longitudinal arch compression and metatarsophalangeal joint (MPJ) excursion, and to determine how these mechanisms modulate strain, and thus elastic energy storage/return of the plantar fascia during running. Eighteen runners (9 forefoot and 9 rearfoot strike) performed three treadmill running trials; unrestricted shod, shod with restricted arch compression (via an orthotic-style insert), and barefoot. Three-dimensional motion capture and ground reaction force data were used to calculate lower limb kinematics and kinetics including MPJ angles, moments, powers and work. Estimates of plantar fascia strain due to arch compression and MPJ excursion were derived using a geometric model of the arch and a subject-specific musculoskeletal model of the plantar fascia, respectively. The plantar fascia exhibited a typical elastic stretch-shortening cycle with the majority of strain generated via arch compression. This strategy was similar in fore- and rear-foot strike runners. Restricting arch compression, and hence the elastic-spring function of the arch, was not compensated for by an increase in MPJ-derived strain. In the second half of stance the plantar fascia was found to transfer energy between the MPJ (energy absorption) and the arch (energy production during recoil). This previously unreported energy transfer mechanism reduces the strain required by the plantar fascia in generating useful positive mechanical work at the arch during running. PMID:27054319

  3. The Role of Arch Compression and Metatarsophalangeal Joint Dynamics in Modulating Plantar Fascia Strain in Running.

    Directory of Open Access Journals (Sweden)

    Kirsty A McDonald

    Full Text Available Elastic energy returned from passive-elastic structures of the lower limb is fundamental in lowering the mechanical demand on muscles during running. The purpose of this study was to investigate the two length-modulating mechanisms of the plantar fascia, namely medial longitudinal arch compression and metatarsophalangeal joint (MPJ excursion, and to determine how these mechanisms modulate strain, and thus elastic energy storage/return of the plantar fascia during running. Eighteen runners (9 forefoot and 9 rearfoot strike performed three treadmill running trials; unrestricted shod, shod with restricted arch compression (via an orthotic-style insert, and barefoot. Three-dimensional motion capture and ground reaction force data were used to calculate lower limb kinematics and kinetics including MPJ angles, moments, powers and work. Estimates of plantar fascia strain due to arch compression and MPJ excursion were derived using a geometric model of the arch and a subject-specific musculoskeletal model of the plantar fascia, respectively. The plantar fascia exhibited a typical elastic stretch-shortening cycle with the majority of strain generated via arch compression. This strategy was similar in fore- and rear-foot strike runners. Restricting arch compression, and hence the elastic-spring function of the arch, was not compensated for by an increase in MPJ-derived strain. In the second half of stance the plantar fascia was found to transfer energy between the MPJ (energy absorption and the arch (energy production during recoil. This previously unreported energy transfer mechanism reduces the strain required by the plantar fascia in generating useful positive mechanical work at the arch during running.

  4. The Role of Arch Compression and Metatarsophalangeal Joint Dynamics in Modulating Plantar Fascia Strain in Running.

    Science.gov (United States)

    McDonald, Kirsty A; Stearne, Sarah M; Alderson, Jacqueline A; North, Ian; Pires, Neville J; Rubenson, Jonas

    2016-01-01

    Elastic energy returned from passive-elastic structures of the lower limb is fundamental in lowering the mechanical demand on muscles during running. The purpose of this study was to investigate the two length-modulating mechanisms of the plantar fascia, namely medial longitudinal arch compression and metatarsophalangeal joint (MPJ) excursion, and to determine how these mechanisms modulate strain, and thus elastic energy storage/return of the plantar fascia during running. Eighteen runners (9 forefoot and 9 rearfoot strike) performed three treadmill running trials; unrestricted shod, shod with restricted arch compression (via an orthotic-style insert), and barefoot. Three-dimensional motion capture and ground reaction force data were used to calculate lower limb kinematics and kinetics including MPJ angles, moments, powers and work. Estimates of plantar fascia strain due to arch compression and MPJ excursion were derived using a geometric model of the arch and a subject-specific musculoskeletal model of the plantar fascia, respectively. The plantar fascia exhibited a typical elastic stretch-shortening cycle with the majority of strain generated via arch compression. This strategy was similar in fore- and rear-foot strike runners. Restricting arch compression, and hence the elastic-spring function of the arch, was not compensated for by an increase in MPJ-derived strain. In the second half of stance the plantar fascia was found to transfer energy between the MPJ (energy absorption) and the arch (energy production during recoil). This previously unreported energy transfer mechanism reduces the strain required by the plantar fascia in generating useful positive mechanical work at the arch during running.

  5. Critical Assessment of Pressure Gauges for ITER

    International Nuclear Information System (INIS)

    Tabares, Francisco L.; Tafalla, David; Garcia-Cortes, Isabel

    2008-01-01

    The density and flux of molecular species in ITER, largely dominated by the molecular form of the main plasma components and the He ash, is a valuable parameter of relevance not only for operation purposes but also for validating existing neutral particle models of direct implications in divertor performance. An accurate and spatially resolved monitoring of this parameter implies the proper selection of pressure gauges able to cope with the very unique and aggressive environment to be expected in a fusion reactor. To date, there is no standard gauge fulfilling all the requirements, which encompass high neutron and gamma fluxes, together with strong magnetic field and temperature excursions and dusty environment. In the present work, a review of the challenges to face in the measurement of neutral pressure in ITER, together with existing technologies and developments to be made in some of them for their application to the task is presented. Particular attention is paid to R and D needs of existing concepts with potential use in future designs

  6. Mass functions from the excursion set model

    Science.gov (United States)

    Hiotelis, Nicos; Del Popolo, Antonino

    2017-11-01

    Aims: We aim to study the stochastic evolution of the smoothed overdensity δ at scale S of the form δ(S) = ∫0S K(S,u)dW(u), where K is a kernel and dW is the usual Wiener process. Methods: For a Gaussian density field, smoothed by the top-hat filter, in real space, we used a simple kernel that gives the correct correlation between scales. A Monte Carlo procedure was used to construct random walks and to calculate first crossing distributions and consequently mass functions for a constant barrier. Results: We show that the evolution considered here improves the agreement with the results of N-body simulations relative to analytical approximations which have been proposed from the same problem by other authors. In fact, we show that an evolution which is fully consistent with the ideas of the excursion set model, describes accurately the mass function of dark matter haloes for values of ν ≤ 1 and underestimates the number of larger haloes. Finally, we show that a constant threshold of collapse, lower than it is usually used, it is able to produce a mass function which approximates the results of N-body simulations for a variety of redshifts and for a wide range of masses. Conclusions: A mass function in good agreement with N-body simulations can be obtained analytically using a lower than usual constant collapse threshold.

  7. Accurate Predictions of Mean Geomagnetic Dipole Excursion and Reversal Frequencies, Mean Paleomagnetic Field Intensity, and the Radius of Earth's Core Using McLeod's Rule

    Science.gov (United States)

    Voorhies, Coerte V.; Conrad, Joy

    1996-01-01

    The geomagnetic spatial power spectrum R(sub n)(r) is the mean square magnetic induction represented by degree n spherical harmonic coefficients of the internal scalar potential averaged over the geocentric sphere of radius r. McLeod's Rule for the magnetic field generated by Earth's core geodynamo says that the expected core surface power spectrum (R(sub nc)(c)) is inversely proportional to (2n + 1) for 1 less than n less than or equal to N(sub E). McLeod's Rule is verified by locating Earth's core with main field models of Magsat data; the estimated core radius of 3485 kn is close to the seismologic value for c of 3480 km. McLeod's Rule and similar forms are then calibrated with the model values of R(sub n) for 3 less than or = n less than or = 12. Extrapolation to the degree 1 dipole predicts the expectation value of Earth's dipole moment to be about 5.89 x 10(exp 22) Am(exp 2)rms (74.5% of the 1980 value) and the expected geomagnetic intensity to be about 35.6 (mu)T rms at Earth's surface. Archeo- and paleomagnetic field intensity data show these and related predictions to be reasonably accurate. The probability distribution chi(exp 2) with 2n+1 degrees of freedom is assigned to (2n + 1)R(sub nc)/(R(sub nc). Extending this to the dipole implies that an exceptionally weak absolute dipole moment (less than or = 20% of the 1980 value) will exist during 2.5% of geologic time. The mean duration for such major geomagnetic dipole power excursions, one quarter of which feature durable axial dipole reversal, is estimated from the modern dipole power time-scale and the statistical model of excursions. The resulting mean excursion duration of 2767 years forces us to predict an average of 9.04 excursions per million years, 2.26 axial dipole reversals per million years, and a mean reversal duration of 5533 years. Paleomagnetic data show these predictions to be quite accurate. McLeod's Rule led to accurate predictions of Earth's core radius, mean paleomagnetic field

  8. System for Rapid, Precise Modulation of Intraocular Pressure, toward Minimally-Invasive In Vivo Measurement of Intracranial Pressure.

    Directory of Open Access Journals (Sweden)

    Max A Stockslager

    Full Text Available Pathologic changes in intracranial pressure (ICP are commonly observed in a variety of medical conditions, including traumatic brain injury, stroke, brain tumors, and glaucoma. However, current ICP measurement techniques are invasive, requiring a lumbar puncture or surgical insertion of a cannula into the cerebrospinal fluid (CSF-filled ventricles of the brain. A potential alternative approach to ICP measurement leverages the unique anatomy of the central retinal vein, which is exposed to both intraocular pressure (IOP and ICP as it travels inside the eye and through the optic nerve; manipulating IOP while observing changes in the natural pulsations of the central retinal vein could potentially provide an accurate, indirect measure of ICP. As a step toward implementing this technique, we describe the design, fabrication, and characterization of a system that is capable of manipulating IOP in vivo with <0.1 mmHg resolution and settling times less than 2 seconds. In vitro tests were carried out to characterize system performance. Then, as a proof of concept, we used the system to manipulate IOP in tree shrews (Tupaia belangeri while video of the retinal vessels was recorded and the caliber of a selected vein was quantified. Modulating IOP using our system elicited a rapid change in the appearance of the retinal vein of interest: IOP was lowered from 10 to 3 mmHg, and retinal vein caliber sharply increased as IOP decreased from 7 to 5 mmHg. Another important feature of this technology is its capability to measure ocular compliance and outflow facility in vivo, as demonstrated in tree shrews. Collectively, these proof-of-concept demonstrations support the utility of this system to manipulate IOP for a variety of useful applications in ocular biomechanics, and provide a framework for further study of the mechanisms of retinal venous pulsation.

  9. Validation of the U.S. NRC coupled code system TRITON/TRACE/PARCS with the special power excursion reactor test III (SPERT III)

    Energy Technology Data Exchange (ETDEWEB)

    Wang, R. C.; Xu, Y.; Downar, T. [Dept. of Nuclear Engineering and Radiological Sciences, Univ. of Michigan, Ann Arbor, MI 48104 (United States); Hudson, N. [RES Div., U.S. NRC, Rockville, MD (United States)

    2012-07-01

    The Special Power Excursion Reactor Test III (SPERT III) was a series of reactivity insertion experiments conducted in the 1950's. This paper describes the validation of the U.S. NRC Coupled Code system TRITON/PARCS/TRACE to simulate reactivity insertion accidents (RIA) by using several of the SPERT III tests. The work here used the SPERT III E-core configuration tests in which the RIA was initiated by ejecting a control rod. The resulting super-prompt reactivity excursion and negative reactivity feedback produced the familiar bell shaped power increase and decrease. The energy deposition during such a power peak has important safety consequences and provides validation basis for core coupled multi-physics codes. The transients of five separate tests are used to benchmark the PARCS/TRACE coupled code. The models were thoroughly validated using the original experiment documentation. (authors)

  10. 40Ar/ 39Ar, K-Ar and 230Th- 238U dating of the Laschamp excursion: A radioisotopic tie-point for ice core and climate chronologies

    Science.gov (United States)

    Singer, Brad S.; Guillou, Hervé; Jicha, Brian R.; Laj, Carlo; Kissel, Catherine; Beard, Brian L.; Johnson, Clark M.

    2009-08-01

    A brief period of enhanced 10Be flux that straddles the interstadial warm period known as Dansgaard-Oeschger event 10 in Greenland and its counterpart in Antarctica, the Antarctic Isotope Maximum 10 is but one consequence of the weakening of Earth's magnetic field associated with the Laschamp excursion. This 10Be peak measured in the GRIP ice core is dated at 41,250 y b2k (= before year 2000 AD) in the most recent GICC05 age model obtained from the NorthGRIP core via multi-parameter counting of annual layers. Uncertainty in the age of the 10Be peak is, however, no better than ± 1630 y at the 95% confidence level, reflecting accumulated error in identifying annual layers. The age of the Laschamp excursion [Guillou, H., Singer, B.S., Laj, C., Kissel, C., Scaillet, S., Jicha, B., 2004. On the age of the Laschamp geomagnetic excursion. Earth Planet. Sci. Lett. 227, 331-343.] is revised on the basis of new 40Ar/ 39Ar, unspiked K-Ar and 238U- 230Th data from three lava flows in the Massif Central, France, together with the 40Ar/ 39Ar age of a transitionally magnetized lava flow at Auckland, New Zealand. Combined, these data yield an age of 40,700 ± 950 y b2k, where the uncertainty includes both analytical and systematic ( 40K and 230Th decay constant) errors. Taking the radioisotopic age as a calibration tie point suggests that the layer-counting chronologies for the NorthGRIP and GISP2 ice cores are more accurate and precise than previously thought at depths corresponding to the Laschamp excursion.

  11. Combined electric and pressure cuff pain stimuli for assessing conditioning pain modulation (CPM).

    Science.gov (United States)

    Tsukamoto, M; Petersen, K K; Mørch, C D; Arendt-Nielsen, L

    2017-12-29

    Aims Traditionally, conditioning pain modulation (CPM) can be assessed by applying a test stimulus (TS) before and after application of a conditioning stimulus (CS), which is normally applied extra-segmental. Currently, no studies have attempted to apply the TS and CS to the same site using different stimuli modalities. The aim of this study was to evaluate electrical TS and cuff pressure CS applied to the same experimental site for studying CPM. Methods 20 male volunteers participated in this study, which consisted of stimulations applied by a cuff-algometer (NociTech and Aalborg University, Denmark) and current stimulator (Digitimer DS5, UK), through two Ag/AgCl electrodes (Ambu® Neuroline 700, Denmark). The cuff was wrapped around the lower leg and stimulation electrodes were placed under the cuff and to the same location on the contralateral leg. Electrical TS were applied to the non-dominant leg with or without cuff pressure CS on the dominant (CS1) or the same (non-dominant) leg (CS2, electrode under cuff). The subjects were instructed to rate the electrical evoked pain intensity on a 10-cm continuous visual analog scale (VAS, "0" represented "no pain", and "10" represented "maximal pain"). The pain detection threshold (PDT) was defined as "1" on the VAS scale. Results There was no significant deference in PDT for neither CS1 nor CS2. A median split subanalysis on CPM-responders versus CPM-nonresponders to the TS + CS1 combination. Using this grouping, there was significant increase in PDT when comparing TS to TS + CS1 or TS + CS2 (4.0 mA vs 5.6 mA; P CPM can be evoked in a subgroup of subjects by applying the electrical test stimulus and cuff pressure conditioning stimuli to the same experimental site.

  12. Tricuspid Annular Plane Systolic Excursion (TAPSE in a Patient with Pulmonary Emboli

    Directory of Open Access Journals (Sweden)

    Nicole Zawada

    2018-01-01

    Full Text Available History of present illness: A 60-year-old male with a history of pulmonary emboli (PE presented to the emergency department with exertional shortness of breath following a ten-hour flight. The patient admitted to recently stopping his previously prescribed rivaroxaban. His electrocardiogram (ECG showed findings consistent with a S1Q3T3 pattern. Point-of-care ultrasound (POCUS was performed using the curvilinear probe, which revealed a thrombus in the inferior vena cava (IVC. POCUS using the phased array probe demonstrated an abnormal tricuspid annular plane systolic excursion (TAPSE and a significantly dilated right ventricle (RV. Computed tomography angiogram (CTA showed evidence of acute emboli within the right and left distal main pulmonary arteries, left lobar, and left proximal segmental artery. Additionally, a thrombus was visualized in the left distal subhepatic IVC. The patient was admitted to telemetry for anticoagulation and monitoring. Right heart catheterization revealed a significantly elevated pulmonary artery pressure of 95/27. Significant findings: Video 1 and Image 1 show a thrombus in the patient’s IVC. Video 2 and Images 2-3 demonstrate a positive TAPSE of less than 17mm (blue arrow length with a significantly dilated RV, indicating abnormal excursion of the tricuspid annulus and right ventricular dysfunction. Discussion: Pulmonary embolism is the third leading cause of death from cardiovascular disease following myocardial infarction and stroke.1 Approximately half of all PEs are diagnosed in the emergency department2 and early detection and treatment have been shown to improve outcomes and survival.3 Pulmonary emboli can present with a wide range of symptoms including dyspnea, chest pain, shock, or sustained hypotension, and can even be asymptomatic, making it a potentially challenging diagnosis.4 Studies show a high specificity of over 80% but low sensitivity of lower than 60%, for echocardiography in the diagnosis of PE

  13. Behavior of aircraft antiskid braking systems on dry and wet runway surfaces. A slip-velocity-controlled, pressure-bias-modulated system

    Science.gov (United States)

    Stubbs, S. M.; Tanner, J. A.; Smith, E. G.

    1979-01-01

    The braking and cornering response of a slip velocity controlled, pressure bias modulated aircraft antiskid braking system is investigated. The investigation, conducted on dry and wet runway surfaces, utilized one main gear wheel, brake, and tire assembly of a McDonnell Douglas DC 9 series 10 airplane. The landing gear strut was replaced by a dynamometer. The parameters, which were varied, included the carriage speed, tire loading, yaw angle, tire tread condition, brake system operating pressure, and runway wetness conditions. The effects of each of these parameters on the behavior of the skid control system is presented. Comparisons between data obtained with the skid control system and data obtained from single cycle braking tests without antiskid protection are examined.

  14. High Pressure Angle Gears: Comparison to Typical Gear Designs

    Science.gov (United States)

    Handschuh, Robert F.; Zabrajsek, Andrew J.

    2010-01-01

    A preliminary study has been completed to determine the feasibility of using high-pressure angle gears in aeronautic and space applications. Tests were conducted in the NASA Glenn Research Center (GRC) Spur Gear Test Facility at speeds up to 10,000 rpm and 73 N*m (648 in.*lb) for 3.18, 2.12, and 1.59 module gears (8, 12, and 16 diametral pitch gears), all designed to operate in the same test facility. The 3.18 module (8-diametral pitch), 28 tooth, 20deg pressure angle gears are the GRC baseline test specimen. Also, 2.12 module (12-diametral pitch), 42 tooth, 25deg pressure angle gears were tested. Finally 1.59 module (16-diametral pitch), 56 tooth, 35deg pressure angle gears were tested. The high-pressure angle gears were the most efficient when operated in the high-speed aerospace mode (10,000 rpm, lubricated with a synthetic turbine engine oil), and produced the lowest wear rates when tested with a perfluoroether-based grease. The grease tests were conducted at 150 rpm and 71 N*m (630 in.*lb).

  15. Scope Complexity Options Risks Excursions (SCORE) Factor Mathematical Description.

    Energy Technology Data Exchange (ETDEWEB)

    Gearhart, Jared Lee [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Samberson, Jonell Nicole [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Shettigar, Subhasini [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jungels, John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Welch, Kimberly M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Dean A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-03-01

    The purpose of the Scope, Complexity, Options, Risks, Excursions (SCORE) model is to estimate the relative complexity of design variants of future warhead options, resulting in scores. SCORE factors extend this capability by providing estimates of complexity relative to a base system (i.e., all design options are normalized to one weapon system). First, a clearly defined set of scope elements for a warhead option is established. The complexity of each scope element is estimated by Subject Matter Experts (SMEs), including a level of uncertainty, relative to a specific reference system. When determining factors, complexity estimates for a scope element can be directly tied to the base system or chained together via comparable scope elements in a string of reference systems that ends with the base system. The SCORE analysis process is a growing multi-organizational Nuclear Security Enterprise (NSE) effort, under the management of the NA-12 led Enterprise Modeling and Analysis Consortium (EMAC). Historically, it has provided the data elicitation, integration, and computation needed to support the out-year Life Extension Program (LEP) cost estimates included in the Stockpile Stewardship Management Plan (SSMP).

  16. Excursions in classical analysis pathways to advanced problem solving and undergraduate research

    CERN Document Server

    Chen, Hongwei

    2010-01-01

    Excursions in Classical Analysis introduces undergraduate students to advanced problem solving and undergraduate research in two ways. Firstly, it provides a colourful tour of classical analysis which places a wide variety of problems in their historical context. Secondly, it helps students gain an understanding of mathematical discovery and proof. In demonstrating a variety of possible solutions to the same sample exercise, the reader will come to see how the connections between apparently inapplicable areas of mathematics can be exploited in problem-solving. This book will serve as excellent preparation for participation in mathematics competitions, as a valuable resource for undergraduate mathematics reading courses and seminars and as a supplement text in a course on analysis. It can also be used in independent study, since the chapters are free-standing.

  17. Integral analysis of cavity pressurization in a fuel rod during an ULOF driven TOP with inclusion of surface tension effects on froth gas bubbles and variable cavity conditions due to fuel melting and ejection

    International Nuclear Information System (INIS)

    Royl, P.

    1984-02-01

    The transient cavity pressurization in an ULOF driven TOP excursion has been analyzed for the SPX-1 reactor with an equation of state that allows to simulate the contribution of small froth gas bubbles to the pressure build-up in a fuel pin with inclusion of restraints from surface tension. Calculations were performed for various bubble parameters. Estimates are made for effective gas availabilities at fuel melting which can be used in a cavity model with an ideal gas equation to arrive at similar pressure transients

  18. Intelligent pressure measurement in multiple sensor arrays

    International Nuclear Information System (INIS)

    Matthews, C.A.

    1995-01-01

    Pressure data acquisition has typically consisted of a group of sensors scanned by an electronic or mechanical multiplexer. The data accuracy was dependent upon the temperature stability of the sensors. This paper describes a new method of pressure measurement that combines individual temperature compensated pressure sensors, a microprocessor, and an A/D converter in one module. Each sensor has its own temperature characteristics stored in a look-up table to minimize sensor thermal errors. The result is an intelligent pressure module that can output temperature compensated engineering units over an Ethernet interface. Calibration intervals can be dramatically extended depending upon system accuracy requirements and calibration techniques used

  19. Thermally moderated hollow fiber sorbent modules in rapidly cycled pressure swing adsorption mode for hydrogen purification

    KAUST Repository

    Lively, Ryan P.; Bessho, Naoki; Bhandari, Dhaval A.; Kawajiri, Yoshiaki; Koros, William J.

    2012-01-01

    We describe thermally moderated multi-layered pseudo-monolithic hollow fiber sorbents entities, which can be packed into compact modules to provide small-footprint, efficient H2 purification/CO2 removal systems for use in on-site steam methane reformer product gas separations. Dual-layer hollow fibers are created via dry-jet, wet-quench spinning with an inner "active" core of cellulose acetate (porous binder) and zeolite NaY (69 wt% zeolite NaY) and an external sheath layer of pure cellulose acetate. The co-spun sheath layer reduces the surface porosity of the fiber and was used as a smooth coating surface for a poly(vinyl-alcohol) post-treatment, which reduced the gas permeance through the fiber sorbent by at least 7 orders of magnitude, essentially creating an impermeable sheath layer. The interstitial volume between the individual fibers was filled with a thermally-moderating paraffin wax. CO2 breakthrough experiments on the hollow fiber sorbent modules with and without paraffin wax revealed that the "passively" cooled paraffin wax module had 12.5% longer breakthrough times than the "non-isothermal" module. The latent heat of fusion/melting of the wax offsets the released latent heat of sorption/desorption of the zeolites. One-hundred rapidly cycled pressure swing adsorption cycles were performed on the "passively" cooled hollow fiber sorbents using 25 vol% CO2/75 vol% He (H2 surrogate) at 60 °C and 113 psia, resulting in a product purity of 99.2% and a product recovery of 88.1% thus achieving process conditions and product quality comparable to conventional pellet processes. Isothermal and non-isothermal dynamic modeling of the hollow fiber sorbent module and a traditional packed bed using gPROMS® indicated that the fiber sorbents have sharper fronts (232% sharper) and longer adsorbate breakthrough times (66% longer), further confirming the applicability of the new fiber sorbent approach for H2 purification. © 2012, Hydrogen Energy Publications, LLC

  20. Thermally moderated hollow fiber sorbent modules in rapidly cycled pressure swing adsorption mode for hydrogen purification

    KAUST Repository

    Lively, Ryan P.

    2012-10-01

    We describe thermally moderated multi-layered pseudo-monolithic hollow fiber sorbents entities, which can be packed into compact modules to provide small-footprint, efficient H2 purification/CO2 removal systems for use in on-site steam methane reformer product gas separations. Dual-layer hollow fibers are created via dry-jet, wet-quench spinning with an inner "active" core of cellulose acetate (porous binder) and zeolite NaY (69 wt% zeolite NaY) and an external sheath layer of pure cellulose acetate. The co-spun sheath layer reduces the surface porosity of the fiber and was used as a smooth coating surface for a poly(vinyl-alcohol) post-treatment, which reduced the gas permeance through the fiber sorbent by at least 7 orders of magnitude, essentially creating an impermeable sheath layer. The interstitial volume between the individual fibers was filled with a thermally-moderating paraffin wax. CO2 breakthrough experiments on the hollow fiber sorbent modules with and without paraffin wax revealed that the "passively" cooled paraffin wax module had 12.5% longer breakthrough times than the "non-isothermal" module. The latent heat of fusion/melting of the wax offsets the released latent heat of sorption/desorption of the zeolites. One-hundred rapidly cycled pressure swing adsorption cycles were performed on the "passively" cooled hollow fiber sorbents using 25 vol% CO2/75 vol% He (H2 surrogate) at 60 °C and 113 psia, resulting in a product purity of 99.2% and a product recovery of 88.1% thus achieving process conditions and product quality comparable to conventional pellet processes. Isothermal and non-isothermal dynamic modeling of the hollow fiber sorbent module and a traditional packed bed using gPROMS® indicated that the fiber sorbents have sharper fronts (232% sharper) and longer adsorbate breakthrough times (66% longer), further confirming the applicability of the new fiber sorbent approach for H2 purification. © 2012, Hydrogen Energy Publications, LLC

  1. Temperature-insensitive fiber Bragg grating dynamic pressure sensing system.

    Science.gov (United States)

    Guo, Tuan; Zhao, Qida; Zhang, Hao; Zhang, Chunshu; Huang, Guiling; Xue, Lifang; Dong, Xiaoyi

    2006-08-01

    Temperature-insensitive dynamic pressure measurement using a single fiber Bragg grating (FBG) based on reflection spectrum bandwidth modulation and optical power detection is proposed. A specifically designed double-hole cantilever beam is used to provide a pressure-induced axial strain gradient along the sensing FBG and is also used to modulate the reflection bandwidth of the grating. The bandwidth modulation is immune to spatially uniform temperature effects, and the pressure can be unambiguously determined by measuring the reflected optical power, avoiding the complex wavelength interrogation system. The system acquisition time is up to 85 Hz for dynamic pressure measurement, and the thermal fluctuation is kept less than 1.2% full-scale for a temperature range of -10 degrees C to 80 degrees C.

  2. Pressurized solid oxide fuel cell integral air accumular containment

    Science.gov (United States)

    Gillett, James E.; Zafred, Paolo R.; Basel, Richard A.

    2004-02-10

    A fuel cell generator apparatus contains at least one fuel cell subassembly module in a module housing, where the housing is surrounded by a pressure vessel such that there is an air accumulator space, where the apparatus is associated with an air compressor of a turbine/generator/air compressor system, where pressurized air from the compressor passes into the space and occupies the space and then flows to the fuel cells in the subassembly module, where the air accumulation space provides an accumulator to control any unreacted fuel gas that might flow from the module.

  3. Axion excursions of the landscape during inflation

    Science.gov (United States)

    Palma, Gonzalo A.; Riquelme, Walter

    2017-07-01

    Because of their quantum fluctuations, axion fields had a chance to experience field excursions traversing many minima of their potentials during inflation. We study this situation by analyzing the dynamics of an axion field ψ , present during inflation, with a periodic potential given by v (ψ )=Λ4[1 -cos (ψ /f )]. By assuming that the vacuum expectation value of the field is stabilized at one of its minima, say, ψ =0 , we compute every n -point correlation function of ψ up to first order in Λ4 using the in-in formalism. This computation allows us to identify the distribution function describing the probability of measuring ψ at a particular amplitude during inflation. Because ψ is able to tunnel between the barriers of the potential, we find that the probability distribution function consists of a non-Gaussian multimodal distribution such that the probability of measuring ψ at a minimum of v (ψ ) different from ψ =0 increases with time. As a result, at the end of inflation, different patches of the Universe are characterized by different values of the axion field amplitude, leading to important cosmological phenomenology: (a) Isocurvature fluctuations induced by the axion at the end of inflation could be highly non-Gaussian. (b) If the axion defines the strength of standard model couplings, then one is led to a concrete realization of the multiverse. (c) If the axion corresponds to dark matter, one is led to the possibility that, within our observable Universe, dark matter started with a nontrivial initial condition, implying novel signatures for future surveys.

  4. Role of pressuriser in enhancing pressure control system capability in primary system of 500 MWe PHWR

    Energy Technology Data Exchange (ETDEWEB)

    Walia, M P.S.; Misri, Vijay; Bapat, C N; Sharma, V K [Nuclear Power Corporation, Bhabha Atomic Research Centre, Mumbai (India)

    1994-06-01

    The primary heat transport system of a pressurized heavy water reactor (PHWR) extracts and transports the heat produced in the fuel (located inside coolant channel assemblies) to the steam generators where steam is generated to run the turbo-generator. The heat transport medium (primary coolant) is heavy water which is kept in a pressurized liquid state with the help of a pressure control system. Feed and bleed circuits with associated equipment of PHT main system have traditionally constituted the pressure control system. However, for large size reactors of 500 MWe capacity, a surge tank known as pressurizer was incorporated due to the presence of relatively large inventory in PHT main circuit. The pressurizer acts as a cushion for pressure variations resulting from various transients. This significantly reduces the onerous demand on feed and bleed system, thereby reducing reactor outages on system pressure excursions. The paper describes in detail the pressure control system of 500 MWe PHWR involving pressuriser and feed and bleed system including their functions and instrumentation. The results of mathematical modelling/analysis undertaken to establish the response adequacy of pressure control system, to postulated plant transients vis-a-vis the role of pressurizer are presented. (author). 10 figs.

  5. Ionization asymmetry effects on the properties modulation of atmospheric pressure dielectric barrier discharge sustained by tailored voltage waveforms

    Science.gov (United States)

    Zhang, Z. L.; Nie, Q. Y.; Zhang, X. N.; Wang, Z. B.; Kong, F. R.; Jiang, B. H.; Lim, J. W. M.

    2018-04-01

    The dielectric barrier discharge (DBD) is a promising technology to generate high density and uniform cold plasmas in atmospheric pressure gases. The effective independent tuning of key plasma parameters is quite important for both application-focused and fundamental studies. In this paper, based on a one-dimensional fluid model with semi-kinetics treatment, numerical studies of ionization asymmetry effects on the properties modulation of atmospheric DBD sustained by tailored voltage waveforms are reported. The driving voltage waveform is characterized by an asymmetric-slope fundamental sinusoidal radio frequency signal superimposing one or more harmonics, and the effects of the number of harmonics, phase shift, as well as the fluctuation of harmonics on the sheath dynamics, impact ionization of electrons and key plasma parameters are investigated. The results have shown that the electron density can exhibit a substantial increase due to the effective electron heating by a spatially asymmetric sheath structure. The strategic modulation of harmonics number and phase shift is capable of raising the electron density significantly (e.g., nearly three times in this case), but without a significant increase in the gas temperature. Moreover, by tailoring the fluctuation of harmonics with a steeper slope, a more profound efficiency in electron impact ionization can be achieved, and thus enhancing the electron density effectively. This method then enables a novel alternative approach to realize the independent control of the key plasma parameters under atmospheric pressure.

  6. The ANTARES Optical Module

    CERN Document Server

    Amram, P; Anvar, S; Ardellier-Desages, F E; Aslanides, Elie; Aubert, Jean-Jacques; Azoulay, R; Bailey, D; Basa, S; Battaglieri, M; Bellotti, R; Benhammou, Ya; Bernard, F; Berthier, R; Bertin, V; Billault, M; Blaes, R; Bland, R W; Blondeau, F; De Botton, N R; Boulesteix, J; Brooks, B; Brunner, J; Cafagna, F; Calzas, A; Capone, A; Caponetto, L; Cârloganu, C; Carmona, E; Carr, J; Carton, P H; Cartwright, S L; Cassol, F; Cecchini, S; Ciacio, F; Circella, M; Compere, C; Cooper, S; Coyle, P; Croquette, J; Cuneo, S; Danilov, M; Van Dantzig, R; De Marzo, C; De Vita, R; Deck, P; Destelle, J J; Dispau, G; Drougou, J F; Druillole, F; Engelen, J; Feinstein, F; Festy, D; Fopma, J; Gallone, J M; Giacomelli, G; Goret, P; Gosset, L G; Gournay, J F; Heijboer, A; Hernández-Rey, J J; Herrouin, G; Hubbard, John R; Jacquet, M; De Jong, M; Karolak, M; Kooijman, P M; Kouchner, A; Kudryavtsev, V A; Lachartre, D; Lafoux, H; Lamare, P; Languillat, J C; Laubier, L; Laugier, J P; Le Guen, Y; Le Provost, H; Le Van-Suu, A; Lemoine, L; Lo Nigro, L; Lo Presti, D; Loucatos, Sotirios S; Louis, F; Lyashuk, V I; Magnier, P; Marcelin, M; Margiotta, A; Massol, A; Masullo, R; Mazéas, F; Mazeau, B; Mazure, A; McMillan, J E; Michel, J L; Migneco, E; Millot, C; Mols, P; Montanet, François; Montaruli, T; Morel, J P; Moscoso, L; Navas, S; Nezri, E; Nooren, G J L; Oberski, J; Olivetto, C; Oppelt-pohl, A; Palanque-Delabrouille, Nathalie; Payre, P; Perrin, P; Petruccetti, M; Petta, P; Piattelli, P; Poinsignon, J; Popa, V; Potheau, R; Queinec, Y; Racca, C; Raia, G; Randazzo, N; Rethore, F; Riccobene, G; Ricol, J S; Ripani, M; Roca-Blay, V; Rolin, J F; Rostovtsev, A A; Russo, G V; Sacquin, Yu; Salusti, E; Schuller, J P; Schuster, W; Soirat, J P; Suvorova, O; Spooner, N J C; Spurio, M; Stolarczyk, T; Stubert, D; Taiuti, M; Tao, Charling; Tayalati, Y; Thompson, L F; Tilav, S; Triay, R; Valente, V; Varlamov, I; Vaudaine, G; Vernin, P; De Witt-Huberts, P K A; De Wolf, E; Zakharov, V; Zavatarelli, S; De Dios-Zornoza-Gomez, Juan; Zúñiga, J

    2002-01-01

    The ANTARES collaboration is building a deep sea neutrino telescope in the Mediterranean Sea. This detector will cover a sensitive area of typically 0.1 km-squared and will be equipped with about 1000 optical modules. Each of these optical modules consists of a large area photomultiplier and its associated electronics housed in a pressure resistant glass sphere. The design of the ANTARES optical module, which is a key element of the detector, has been finalized following extensive R & D studies and is reviewed here in detail.

  7. Limnologic-geologic excursion in the territory of the lower Erft River

    Energy Technology Data Exchange (ETDEWEB)

    Friedrich, G.; Thome, K.N.

    1976-01-01

    The geography and hydrology of the area of the excursion are described. There is much damage due to brown coal strip mining operations. Ground water was drained through a canal leading to the Erft River. The water in nearby springs is rich in Fe which repels plant life. The canal contains only a few blue algae (Oscillatoria splendida) and filamentous green algae (Ulothrix tenerrima) which tolerate high Fe concentrations. The Erft shore plant population includes Sparganium erectum, Potamogeton natans, P. pectinatus and Ranunculus fluitans. On flowering plants and stones, diatoms, various green algae (Cladophora glomerata, Stigeoclonium tenue, Oedogonium capillare) and the tropical red alga Compsopogon hookeri were found. The macrozoobenthos is composed mainly of snails (Bithynia tenaculata, Lumnaea ovata, Physa fontinalis, P. acuta and worms of North American origin (Dugesia tifrina, Dendrocoelum lacteum and Planaria lugubris). The Isopoda included Asellus coxalis and A. aquaticus. Leeches (Herpobdella octoculata) and insect larvae (Chironomids, Limnephilids) were also found.

  8. Blood pressure and cardiac autonomic modulation at rest, during exercise and recovery time in the young overweight

    Directory of Open Access Journals (Sweden)

    Jaqueline Alves de Araújo

    2016-03-01

    Full Text Available Abstract This study aimed to assess the blood pressure (BP, cardiac autonomic modulation at rest, in physical exercise and in the recovery in untrained eutrophic (E and overweight (O youth. The body mass index (BMI, waist circumference (WC, systolic BP-SBP (E: 109.80 ± 10.05; O: 121.85 ± 6.98 mmHg and diastolic BP - DBP (E: 65.90 ± 7.28; O: 73.14 ± 12.22 mmHg were higher in overweight and the heart rate recovery (%HRR was lower as compared with E volunteers. The BMI was associated with SBP (r= 0.54, DBP (r= 0.65, load on the heart rate variability threshold - HRVT (r= -0.46, %HRR 2' (r= -0.48 and %HRR 5' (r= -0.48, and WC was associated with SBP (r= 0.54, DBP (r= 0.64 and HRR 2' (r= -0.49. The %HRR was associated to SBP, DBP and HRVT. In summary, the anthropometric variables, BP and cardiac autonomic modulation in the recovery are altered in overweight youth.

  9. The Mono Lake geomagnetic excursion recorded in loess: Its application as time marker and implications for its geomagnetic nature

    Science.gov (United States)

    Hambach, U.; Hark, M.; Zeeden, C.; Reddersen, B.; Zöller, L.; Fuchs, M.

    2009-04-01

    One of the youngest and worldwide documented geomagnetic excursions in the Brunhes Chron is the Mono Lake excursion (MLE). It has been detected in marine and terrestrial sedimentary archives as well as in lavas. Recent age determinations and age estimates for the MLE centre around an age interval of approximately 31 - 34 ka. Likewise the Laschamp excursion the MLE goes along with a distinct peak in cosmogenic radionuclides in ice cores and sedimentary archives. It provides therefore an additional geomagnetic time marker for various geoarchives to synchronise different climate archives. Here we report on a detailed record of the MLE from a loess site at Krems, Lower Austria. The site is situated on the southern slope of the Wachtberg hill in the vicinity of the old city centre of Krems. The archive comprises Middle to Upper Würmian (Late Pleistocene) loess in which an Upper Palaeolithic (Early Gravettian) cultural layer is embedded. The most spectacular finds are a double infant burial found in 2005 and a single burial discovered in 2006 (Einwögerer et al., 2006). Generally, archaeological findings show an extraordinarily good preservation due to embedding in rapidly sedimented loess (Händel et al., 2008). The about 10 m thick loess pile consists of calcareous sandy, coarse silt which is rich in mica indicating local sources. It is well stratified with brownish horizons representing embryonic soils pointing to incipient pedogenesis. Some of the pedo-horizons show occasionally indications of minor erosion and bedding-parallel sediment transport, but no linear erosional features. Pale greyish horizons are the result of partial gleying under permafrost conditions. No strong pedogenesis including decalcification and clay formation is present. The cultural layer is still covered by more than 5 m of loess, and dated by radiocarbon to ~27 ka 14C BP (Einwögerer et al., 2006). Below this layer up to 2.5 m of loess resting on Lower Pleistocene fluvial gravels are

  10. The ANTARES optical module

    Energy Technology Data Exchange (ETDEWEB)

    Amram, P.; Anghinolfi, M.; Anvar, S.; Ardellier-Desages, F.E.; Aslanides, E.; Aubert, J.-J.; Azoulay, R.; Bailey, D.; Basa, S.; Battaglieri, M.; Bellotti, R.; Benhammou, Y.; Bernard, F.; Berthier, R.; Bertin, V.; Billault, M.; Blaes, R.; Bland, R.W.; Blondeau, F.; Botton, N. de; Boulesteix, J.; Brooks, C.B.; Brunner, J.; Cafagna, F.; Calzas, A.; Capone, A.; Caponetto, L.; Carloganu, C.; Carmona, E.; Carr, J.; Carton, P.-H.; Cartwright, S.L.; Cassol, F.; Cecchini, S.; Ciacio, F.; Circella, M.; Compere, C.; Cooper, S.; Coyle, P.; Croquette, J.; Cuneo, S.; Danilov, M.; Dantzig, R. van; De Marzo, C.; DeVita, R.; Deck, P.; Destelle, J.-J.; Dispau, G.; Drougou, J.F.; Druillole, F.; Engelen, J.; Feinstein, F.; Festy, D.; Fopma, J.; Gallone, J.-M.; Giacomelli, G.; Goret, P.; Gosset, L.; Gournay, J.-F.; Heijboer, A.; Hernandez-Rey, J.J.; Herrouin, G.; Hubbard, J.R.; Jaquet, M.; Jong, M. de; Karolak, M.; Kooijman, P.; Kouchner, A.; Kudryavtsev, V.A.; Lachartre, D.; Lafoux, H. E-mail: lafoux@cea.fr; Lamare, P.; Languillat, J.-C.; Laubier, L.; Laugier, J.-P.; Le Guen, Y.; Le Provost, H.; Le Van Suu, A.; Lemoine, L.; Lo Nigro, L.; Lo Presti, D.; Loucatos, S.; Louis, F.; Lyashuk, V.; Magnier, P.; Marcelin, M.; Margiotta, A.; Massol, A.; Masullo, R.; Mazeas, F.; Mazeau, B.; Mazure, A.; McMillan, J.E.; Michel, J.L.; Migneco, E.; Millot, C.; Mols, P.; Montanet, F.; Montaruli, T.; Morel, J.P.; Moscoso, L.; Musumeci, M.; Navas, S.; Nezri, E.; Nooren, G.J.; Oberski, J.; Olivetto, C.; Oppelt-Pohl, A.; Palanque-Delabrouille, N.; Papaleo, R.; Payre, P.; Perrin, P.; Petruccetti, M.; Petta, C.; Piattelli, P.; Poinsignon, J.; Potheau, R.; Queinec, Y.; Racca, C.; Raia, G.; Randazzo, N.; Rethore, F.; Riccobene, G.; Ricol, J.-S.; Ripani, M.; Roca-Blay, V.; Rolin, J.F.; Rostovstev, A.; Russo, G.V.; Sacquin, Y.; Salusti, E.; Schuller, J.-P.; Schuster, W.; Soirat, J.-P.; Souvorova, O.; Spooner, N.J.C.; Spurio, M.; Stolarczyk, T.; Stubert, D.; Taiuti, M.; Tao, C.; Tayalati, Y.; Thompson, L.F.

    2002-05-21

    The ANTARES collaboration is building a deep sea neutrino telescope in the Mediterranean Sea. This detector will cover a sensitive area of typically 0.1 km{sup 2} and will be equipped with about 1000 optical modules. Each of these optical modules consists of a large area photomultiplier and its associated electronics housed in a pressure resistant glass sphere. The design of the ANTARES optical module, which is a key element of the detector, has been finalized following extensive R and D studies and is reviewed here in detail.

  11. The ANTARES optical module

    International Nuclear Information System (INIS)

    Amram, P.; Anghinolfi, M.; Anvar, S.; Ardellier-Desages, F.E.; Aslanides, E.; Aubert, J.-J.; Azoulay, R.; Bailey, D.; Basa, S.; Battaglieri, M.; Bellotti, R.; Benhammou, Y.; Bernard, F.; Berthier, R.; Bertin, V.; Billault, M.; Blaes, R.; Bland, R.W.; Blondeau, F.; Botton, N. de; Boulesteix, J.; Brooks, C.B.; Brunner, J.; Cafagna, F.; Calzas, A.; Capone, A.; Caponetto, L.; Carloganu, C.; Carmona, E.; Carr, J.; Carton, P.-H.; Cartwright, S.L.; Cassol, F.; Cecchini, S.; Ciacio, F.; Circella, M.; Compere, C.; Cooper, S.; Coyle, P.; Croquette, J.; Cuneo, S.; Danilov, M.; Dantzig, R. van; De Marzo, C.; DeVita, R.; Deck, P.; Destelle, J.-J.; Dispau, G.; Drougou, J.F.; Druillole, F.; Engelen, J.; Feinstein, F.; Festy, D.; Fopma, J.; Gallone, J.-M.; Giacomelli, G.; Goret, P.; Gosset, L.; Gournay, J.-F.; Heijboer, A.; Hernandez-Rey, J.J.; Herrouin, G.; Hubbard, J.R.; Jaquet, M.; Jong, M. de; Karolak, M.; Kooijman, P.; Kouchner, A.; Kudryavtsev, V.A.; Lachartre, D.; Lafoux, H.; Lamare, P.; Languillat, J.-C.; Laubier, L.; Laugier, J.-P.; Le Guen, Y.; Le Provost, H.; Le Van Suu, A.; Lemoine, L.; Lo Nigro, L.; Lo Presti, D.; Loucatos, S.; Louis, F.; Lyashuk, V.; Magnier, P.; Marcelin, M.; Margiotta, A.; Massol, A.; Masullo, R.; Mazeas, F.; Mazeau, B.; Mazure, A.; McMillan, J.E.; Michel, J.L.; Migneco, E.; Millot, C.; Mols, P.; Montanet, F.; Montaruli, T.; Morel, J.P.; Moscoso, L.; Musumeci, M.; Navas, S.; Nezri, E.; Nooren, G.J.; Oberski, J.; Olivetto, C.; Oppelt-Pohl, A.; Palanque-Delabrouille, N.; Papaleo, R.; Payre, P.; Perrin, P.; Petruccetti, M.; Petta, C.; Piattelli, P.; Poinsignon, J.; Potheau, R.; Queinec, Y.; Racca, C.; Raia, G.; Randazzo, N.; Rethore, F.; Riccobene, G.; Ricol, J.-S.; Ripani, M.; Roca-Blay, V.; Rolin, J.F.; Rostovstev, A.; Russo, G.V.; Sacquin, Y.; Salusti, E.; Schuller, J.-P.; Schuster, W.; Soirat, J.-P.; Souvorova, O.; Spooner, N.J.C.; Spurio, M.; Stolarczyk, T.; Stubert, D.; Taiuti, M.; Tao, C.; Tayalati, Y.; Thompson, L.F.; Tilav, S.; Triay, R.; Valente, V.; Varlamov, I.; Vaudaine, G.; Vernin, P.; Witt Huberts, P. de; Wolf, E. de; Zakharov, V.; Zavatarelli, S.; D Zornoza, J. de; Zuniga, J.

    2002-01-01

    The ANTARES collaboration is building a deep sea neutrino telescope in the Mediterranean Sea. This detector will cover a sensitive area of typically 0.1 km 2 and will be equipped with about 1000 optical modules. Each of these optical modules consists of a large area photomultiplier and its associated electronics housed in a pressure resistant glass sphere. The design of the ANTARES optical module, which is a key element of the detector, has been finalized following extensive R and D studies and is reviewed here in detail

  12. DEVELOPMENT OF PRESSURIZED CIRCULATING FLUIDIZED BED PARTIAL GASIFICATION MODULE (PGM)

    International Nuclear Information System (INIS)

    Unknown

    2001-01-01

    Foster Wheeler Development Corporation is working under DOE contract No. DE-FC26-00NT40972 to develop a partial gasification module (PGM) that represents a critical element of several potential coal-fired Vision 21 plants. When utilized for electrical power generation, these plants will operate with efficiencies greater than 60% while producing near zero emissions of traditional stack gas pollutants. The new process partially gasifies coal at elevated pressure producing a coal-derived syngas and a char residue. The syngas can be used to fuel the most advanced power producing equipment such as solid oxide fuel cells or gas turbines or processed to produce clean liquid fuels or chemicals for industrial users. The char residue is not wasted; it can also be used to generate electricity by fueling boilers that drive the most advanced ultra-supercritical pressure steam turbines. The unique aspect of the process is that it utilizes a pressurized circulating fluidized bed partial gasifier and does not attempt to consume the coal in a single step. To convert all the coal to syngas in a single step requires extremely high temperatures ((approx)2500 to 2800F) that melt and vaporize the coal and essentially drive all coal ash contaminants into the syngas. Since these contaminants can be corrosive to power generating equipment, the syngas must be cooled to near room temperature to enable a series of chemical processes to clean the syngas. Foster Wheeler's process operates at much lower temperatures that control/minimize the release of contaminants; this eliminates/minimizes the need for the expensive, complicated syngas heat exchangers and chemical cleanup systems typical of high temperature gasification. By performing the gasification in a circulating bed, a significant amount of syngas can still be produced despite the reduced temperature and the circulating bed allows easy scale up to large size plants. Rather than air, it can also operate with oxygen to facilitate

  13. Some local dilution transient in a pressurized water reactor

    International Nuclear Information System (INIS)

    Jacobson, S.

    1989-01-01

    Reactivity accidents are important in the safety analysis of a pressurized water reactor. In this anlysis ejected control rod, steam line break, start of in-active loop and boron dilution accidents are usually dealt with. However, in the analysis is not included what reactivity excursions might happen when a zone,depleted of boron passes the reactor core. This thesis investigates during what operation and emergency conditions diluted zones might exist in a pressurized water reactor and what should be the maximum volumes for then. The limiting transport means are also established in terms of reactivty addition, for the depleted zones. In order to describe the complicated mixing process in the reactor vessel during such a transportation, a typical 3-loop reactor vessel has been modulated by means of TRAC-PF1's VESSEL component. Three cases have been analysed. In the first case the reactor is in a cold condition and the ractor coolant has boron concentration of 2000 ppm. To the reactor vessel is injected an clean water colume of 14 m 3 . In the two other cases the reactor is close to hot shutdown and borated to 850 ppm. To the reactor vessel is added 41 and 13 m 3 clean water, respectively. In the thesis is shown what spatial distribution the depleted zone gets when passing through the reactor vessel in the three cases. The boron concentration in the first case did not decrease the values which would bring the reactor to critical condition. For case two was shown by means of TRAC's point kinetics model that the reactor reaches prompt criticality after 16.03 seconds after starting of the reactor coolant pump. Another prompt criticality occured two seconds later. The total energy developed during the two power escalations were about 55 GJ. A comparision with the criteria used to evaluate the ejected control rod reactivity transient showed that none of these criteria were exceeded. (64 figs.)

  14. Pressure modulation of Ras-membrane interactions and intervesicle transfer.

    Science.gov (United States)

    Kapoor, Shobhna; Werkmüller, Alexander; Goody, Roger S; Waldmann, Herbert; Winter, Roland

    2013-04-24

    Proteins attached to the plasma membrane frequently encounter mechanical stresses, including high hydrostatic pressure (HHP) stress. Signaling pathways involving membrane-associated small GTPases (e.g., Ras) have been identified as critical loci for pressure perturbation. However, the impact of mechanical stimuli on biological outputs is still largely terra incognita. The present study explores the effect of HHP on the membrane association, dissociation, and intervesicle transfer process of N-Ras by using a FRET-based assay to obtain the kinetic parameters and volumetric properties along the reaction path of these processes. Notably, membrane association is fostered upon pressurization. Conversely, depending on the nature and lateral organization of the lipid membrane, acceleration or retardation is observed for the dissociation step. In addition, HHP can be inferred as a positive regulator of N-Ras clustering, in particular in heterogeneous membranes. The susceptibility of membrane interaction to pressure raises the idea of a role of lipidated signaling molecules as mechanosensors, transducing mechanical stimuli to chemical signals by regulating their membrane binding and dissociation. Finally, our results provide first insights into the influence of pressure on membrane-associated Ras-controlled signaling events in organisms living under extreme environmental conditions such as those that are encountered in the deep sea and sub-seafloor environments, where pressures reach the kilobar (100 MPa) range.

  15. Under pressure: response urgency modulates striatal and insula activity during decision-making under risk.

    Science.gov (United States)

    Jones, Catherine L; Minati, Ludovico; Harrison, Neil A; Ward, Jamie; Critchley, Hugo D

    2011-01-01

    When deciding whether to bet in situations that involve potential monetary loss or gain (mixed gambles), a subjective sense of pressure can influence the evaluation of the expected utility associated with each choice option. Here, we explored how gambling decisions, their psychophysiological and neural counterparts are modulated by an induced sense of urgency to respond. Urgency influenced decision times and evoked heart rate responses, interacting with the expected value of each gamble. Using functional MRI, we observed that this interaction was associated with changes in the activity of the striatum, a critical region for both reward and choice selection, and within the insula, a region implicated as the substrate of affective feelings arising from interoceptive signals which influence motivational behavior. Our findings bridge current psychophysiological and neurobiological models of value representation and action-programming, identifying the striatum and insular cortex as the key substrates of decision-making under risk and urgency.

  16. High pressure water jet mining machine

    Science.gov (United States)

    Barker, Clark R.

    1981-05-05

    A high pressure water jet mining machine for the longwall mining of coal is described. The machine is generally in the shape of a plowshare and is advanced in the direction in which the coal is cut. The machine has mounted thereon a plurality of nozzle modules each containing a high pressure water jet nozzle disposed to oscillate in a particular plane. The nozzle modules are oriented to cut in vertical and horizontal planes on the leading edge of the machine and the coal so cut is cleaved off by the wedge-shaped body.

  17. Reliability of the Star Excursion Balance Test and Two New Similar Protocols to Measure Trunk Postural Control.

    Science.gov (United States)

    López-Plaza, Diego; Juan-Recio, Casto; Barbado, David; Ruiz-Pérez, Iñaki; Vera-Garcia, Francisco J

    2018-05-18

    Although the Star Excursion Balance test (SEBT) has shown a good intrasession reliability, the intersession reliability of this test has not been deeply studied. Furthermore, there is an evident high influence of the lower limbs in the performance of the SEBT, so even if it has been used to measure core stability, it is possibly not the most suitable measurement. The aims of this study were to (1) to assess the absolute and relative between-session reliability of the SEBT and 2 novel variations of this test to assess trunk postural control while sitting, ie, the Star Excursion Sitting Test (SEST) and the Star Excursion Timing Test (SETT); and (2) to analyze the relationships between these 3 test scores. Correlational and reliability test-retest study. Controlled laboratory environment. Twenty-seven physically active men (age: 24.54 ± 3.05 years). Relative and absolute reliability of the SEBT, SEST, and SETT were calculated through the intraclass correlation coefficient (ICC) and standard error of measurement (SEM), respectively. A Pearson correlation analysis was carried out between the variables of the 3 tests. Maximum normalized reach distances were assessed for different SEBT and SEST directions. In addition, composite indexes were calculated for SEBT, SEST, and SETT. The SEBT (dominant leg: ICC = 0.87 [0.73-0.94], SEM = 2.12 [1.66-2.93]; nondominant leg: ICC = 0.74 [0.50-0.87], SEM = 3.23 [2.54-4.45]), SEST (ICC = 0.85 [0.68-0.92], SEM = 1.27 [1.03-1.80]), and SETT (ICC = 0.61 [0.30-0.80], SEM = 2.31 [1.82-3.17]) composite indexes showed moderate-to-high 1-month reliability. A learning effect was detected for some SEBT and SEST directions and for SEST and SETT composite indexes. No significant correlations were found between SEBT and its 2 variations (r ≤ .366; P > .05). A significant correlation was found between the SEST and SETT composite indexes (r = .520; P > .01). SEBT, SEST, and SETT are reliable field protocols to measure postural control. However

  18. Acoustic emission test on a 25mm thick mild steel pressure vessel with inserted defects

    International Nuclear Information System (INIS)

    Bentley, P.G.; Dawson, D.G.; Hanley, D.J.; Kirby, N.

    1976-12-01

    Acoustic emission measurements have been taken on an experimental mild steel vessel with 4 inserted defects ranging in severity up to 90% of through thickness. The vessel was subjected to a series of pressure excursions of increasing magnitude until failure occurred by extension of the largest inserted defect through the vessel wall. No acoustic emission was detected throughout any part of the tests which would indicate the presence of such serious defects or of impending failure. Measurements of acoustic emission from metallurgical specimens are included and the results of post test inspection using conventional NDT and metallographic techniques are reported. (author)

  19. Reliability of an HTR-module primary circuit pressure boundary. Influences, sensitivity, and comparison with a PWR

    International Nuclear Information System (INIS)

    Staat, M.

    1995-01-01

    The reliability of the HTR-module for electricity and steam generation was analysed for normal operation, as well as accident conditions. The probabilistic fracture mechanics assessment was performed with a modification of the ZERBERUS code on the basis of widely used data. The calculated failure probabilities may thus be compared with similar investigations. The HTR-module primary circuit pressure boundary as a unit showed leak-before-break behaviour in a probabilistic sense, although a break was more probable than a leak for some of its parts.However, the findings may depend greatly on the stochastic data. Therefore a stochastic reference problem is defined and the results are compared with the Japanese round robin on a PWR section. Possible changes of failure probabilities and of the leak-before-break behaviour are discussed for different criteria for the events leading to a leak, and for modifications of the stochastic reference problem such as the inclusion of NDE. The results may be used to identify those stochastic variables which have the greatest influence on the computed failure probabilities, and to perhaps justify further work which would provide more detailed information on these probabilities. Furthermore, there is an obvious need for reduction of the non-statistical reasons for great variations of failure probabilities. (orig.)

  20. Glycemic excursions are positively associated with HbA1c reduction from baseline after treatment with acarbose in patients with type 2 diabetes on metformin monotherapy.

    Science.gov (United States)

    Wang, Jun-Sing; Lee, I-Te; Lee, Wen-Jane; Lin, Shi-Dou; Su, Shih-Li; Tu, Shih-Te; Tseng, Yao-Hsien; Lin, Shih-Yi; Sheu, Wayne Huey-Herng

    2017-03-01

    The aim of the present study was to examine the association between glycemic excursions before treatment and HbA1c reduction after treatment intensification with acarbose or glibenclamide in patients with type 2 diabetes (T2D). Patients receiving single or dual oral antidiabetic drug treatment with an HbA1c of 7.0-11.0 % (53-97 mmol/mol) were switched to metformin monotherapy (500 mg, t.i.d.) for 8 weeks, followed by randomization to either acarbose (100 mg, t.i.d.) or glibenclamide (5 mg, t.i.d.) as add-on treatment for 16 weeks. Glycemic excursions were assessed as mean amplitude of glycemic excursions (MAGE) with 72-h ambulatory continuous glucose monitoring. Treatment efficacy was evaluated as relative HbA1c reduction (%), calculated as (baseline HbA1c - post-treatment HbA1c)/baseline HbA1c × 100. Fifty patients (mean [±SD] age 53.5 ± 8.2 years, 48 % men, mean baseline HbA1c 8.4 ± 1.2 %) were analyzed. Baseline MAGE was positively correlated with relative HbA1c reduction from baseline in patients treated with acarbose (r = 0.421, P = 0.029) but not glibenclamide (r = 0.052, P = 0.813). Linear regression analysis revealed that the association between baseline MAGE and relative HbA1c reduction from baseline (β = 0.125, P = 0.029) in patients treated with acarbose remained significant after adjustment for several confounders (P HbA1c reduction from baseline after treatment with acarbose, but not glibenclamide. These findings highlight the importance of glycemic excursions in individualized treatment for patients with T2D. © 2016 Ruijin Hospital, Shanghai JiaoTong University School of Medicine (SJTU), Chinese Society of Endocrinology and Chinese Endocrinologist Association and John Wiley & Sons Australia, Ltd.

  1. Analysis of hypothetical nuclear excursions in the external core retention system

    International Nuclear Information System (INIS)

    Froehlich, R.; Kussmaul, G.; Schmuck, P.

    1976-01-01

    The core catcher system of the SNR 300 is outside the reactor tank. The probability of recriticality phenomena is reduced by its design, but the licensing procedures still call for the analysis of strong recriticality phenomena in the core catcher system outside the reactor tank in order to achieve a better understanding of the possible physical effects and to get to know the safety limits of the system. For their theoretical investigations, the authors used a two-partner model as presented in fig. 1. At the bottom of the core catcher - which consists of depleted UO 2 - there is a fuel cylinder. Another fuel cylinder (with the same axis) is dropped from a height of 250 cm. The two cylindrical masses are immersed in sodium, but a free fall is assumed since the possibility cannot be excluded that the reactor bottom may be empty or only partially filled with sodium. It was found that under these conditions the strongest excursions may be expected in those cases where prompt criticality does not occur until just before the two partners meet. (orig./AK) [de

  2. Accidental nuclear excursion recuplex operation 234-5 facility: Final medical report

    Energy Technology Data Exchange (ETDEWEB)

    Fuqua, P. A.

    1962-04-07

    The April 7, 1962 criticality accident involving human exposures was the first to have occurred in any production facility at Hanford. The accidental nuclear excursion did not result in any mechanical damage or spread of contamination. Three employees received over-exposure to gamma and neutron radiation. None were fatally exposed and in each case the over-exposure was recognized promptly. Following an initial period of medical observation and testing, the men were released to work. They continued to be followed clinically. Clinical studies performed were hematological procedures including leukocyte chromosome aberrations, morphologically aberrant blood cells, bone marrow evaluations, blood chemistry determinations, amino acid excretion studies, seminal fluid, urinary gonadotropins and estrogen excretion studies, testicular biopsies and crystalline lens examinations. These studies, along with a brief description of the accident and of the dosimetry, are summarized in this report by those participating in the studies. In view of the dose ranges received in these cases, both the negative and positive findings are considered to be of unusual interest due to the lack of knowledge of effects following human exposures at these levels.

  3. Scope Complexity Options Risks Excursions (SCORE) Version 3.0 Mathematical Description.

    Energy Technology Data Exchange (ETDEWEB)

    Gearhart, Jared Lee [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Samberson, Jonell Nicole [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Shettigar, Subhasini [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jungels, John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Welch, Kimberly M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Dean A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-03-01

    The purpose of the Scope, Complexity, Options, Risks, Excursions (SCORE) model is to estimate the relative complexity of design variants of future warhead options. The results of this model allow those considering these options to understand the complexity tradeoffs between proposed warhead options. The core idea of SCORE is to divide a warhead option into a well- defined set of scope elements and then estimate the complexity of each scope element against a well understood reference system. The uncertainty associated with estimates can also be captured. A weighted summation of the relative complexity of each scope element is used to determine the total complexity of the proposed warhead option or portions of the warhead option (i.e., a National Work Breakdown Structure code). The SCORE analysis process is a growing multi-organizational Nuclear Security Enterprise (NSE) effort, under the management of the NA- 12 led Enterprise Modeling and Analysis Consortium (EMAC), that has provided the data elicitation, integration and computation needed to support the out-year Life Extension Program (LEP) cost estimates included in the Stockpile Stewardship Management Plan (SSMP).

  4. Under pressure: response urgency modulates striatal and insula activity during decision-making under risk.

    Directory of Open Access Journals (Sweden)

    Catherine L Jones

    Full Text Available When deciding whether to bet in situations that involve potential monetary loss or gain (mixed gambles, a subjective sense of pressure can influence the evaluation of the expected utility associated with each choice option. Here, we explored how gambling decisions, their psychophysiological and neural counterparts are modulated by an induced sense of urgency to respond. Urgency influenced decision times and evoked heart rate responses, interacting with the expected value of each gamble. Using functional MRI, we observed that this interaction was associated with changes in the activity of the striatum, a critical region for both reward and choice selection, and within the insula, a region implicated as the substrate of affective feelings arising from interoceptive signals which influence motivational behavior. Our findings bridge current psychophysiological and neurobiological models of value representation and action-programming, identifying the striatum and insular cortex as the key substrates of decision-making under risk and urgency.

  5. The effect of different skin-ankle brace application pressures on quiet single-limb balance and electromyographic activation onset of lower limb muscles

    Directory of Open Access Journals (Sweden)

    Papadakis Stamatios A

    2007-09-01

    Full Text Available Abstract Background Several studies have been carried out in order to investigate the effect of ankle bracing on ankle joint function and performance. However, no study so far has examined the role of skin-brace interface pressure in neuromuscular control. The aim of this study was to investigate the effect of different skin-ankle brace interface pressures on quiet single limb balance and the electromyographic (EMG activation sequence of four lower limb muscles. Methods Thirty three male physical education students who volunteered to take part in the study were measured under three ankle brace conditions: i without brace, ii with brace and 30 kPa application pressure and iii with brace and 60 kPa application pressure. Single limb balance (anteroposterior and mediolateral parameter was assessed on the dominant lower limb, with open and closed eyes, on a force platform, simultaneously with the EMG recording of four lower lower limb muscles' (gastrocnemius, peroneus longus, rectus femoris and biceps femoris activation onset. Results The results showed that overall balance (total stability parameter was not significantly affected in any of the three ankle brace conditions. However, the anteroposterior centre of pressure excursion and centre of pressure excursion velocity were significantly increased with the application of ankle brace, both with 30 and 60 kPa application pressures. Furthermore, it was found that single limb balance was significantly worse with closed eyes compared to open eyes. EMG measurements showed that the sequence of lower limb activation onset was not affected in any of the three ankle brace application conditions. The results of this study showed that the application of an ankle brace with two different skin-brace interface pressures had no effect on overall single limb balance and the sequence of lower limb muscle activation. Conclusion These findings suggest that peripheral joint receptors are either not adequately

  6. Numerical Study on Flow Characteristics of Hollow Fiber Membrane Module for Water Recovery Cooling Tower

    Energy Technology Data Exchange (ETDEWEB)

    Park, Chang Cheol; Shin, Weon Gyu [Chungnam Nat’l Univ., Daejeon (Korea, Republic of); Park, Hyun Seol; Lee, Hyung Keun [Korea Institute of Energy Research, Daejeon (Korea, Republic of)

    2017-08-15

    The purpose of this study is to analyze the flow characteristics when a staggered hollow fiber membrane module is modeled as a porous medium. The pressure-velocity equation was used for modeling the porous medium, using pressure drop data. In terms of flow characteristics, we compared the case of the 'porous medium' when the membrane module was modeled as a porous medium with the case of the 'membrane module' when considering the original shape of the membrane module. The difference in pressure drop between the 'porous medium' and 'membrane module' was less than 0.6%. However, the maximum flow velocity and mean turbulent kinetic energy of the 'porous medium' were 2.5 and 95 times larger than those of the 'membrane module,' respectively. Our results indicate that modeling the hollow fiber module as a porous medium is useful for predicting pressure drop, but not sufficient for predicting the maximum flow velocity and mean turbulent kinetic energy.

  7. Renal intercalated cells and blood pressure regulation

    Directory of Open Access Journals (Sweden)

    Susan M. Wall

    2017-12-01

    Full Text Available Type B and non-A, non-B intercalated cells are found within the connecting tubule and the cortical collecting duct. Of these cell types, type B intercalated cells are known to mediate Cl⁻ absorption and HCO₃⁻ secretion largely through pendrin-dependent Cl⁻/HCO₃⁻ exchange. This exchange is stimulated by angiotensin II administration and is also stimulated in models of metabolic alkalosis, for instance after aldosterone or NaHCO₃ administration. In some rodent models, pendrin-mediated HCO₃⁻ secretion modulates acid-base balance. However, the role of pendrin in blood pressure regulation is likely of more physiological or clinical significance. Pendrin regulates blood pressure not only by mediating aldosterone-sensitive Cl⁻ absorption, but also by modulating the aldosterone response for epithelial Na⁺ channel (ENaC-mediated Na⁺ absorption. Pendrin regulates ENaC through changes in open channel of probability, channel surface density, and channels subunit total protein abundance. Thus, aldosterone stimulates ENaC activity through both direct and indirect effects, the latter occurring through its stimulation of pendrin expression and function. Therefore, pendrin contributes to the aldosterone pressor response. Pendrin may also modulate blood pressure in part through its action in the adrenal medulla, where it modulates the release of catecholamines, or through an indirect effect on vascular contractile force. This review describes how aldosterone and angiotensin II-induced signaling regulate pendrin and the contributory role of pendrin in distal nephron function and blood pressure.

  8. Automated Seat Cushion for Pressure Ulcer Prevention Using Real-Time Mapping, Offloading, and Redistribution of Interface Pressure

    Science.gov (United States)

    2016-10-01

    of MATLAB image processing routines to identify, sort, and track the location of the intended points (markers), Fig. 12(c). Further, magnification...testing as well as finite element simulation . Automation and control testing has been completed on a 5x5 array of bubble actuators to verify pressure...ulcer prevention, automated seat cushion, bubble actuator, pressure modulation , pressure offloading, wheelchair cushion, spinal cord injury 16. SECURITY

  9. Clayey landslide initiation and acceleration strongly modulated by soil swelling

    Science.gov (United States)

    Schulz, William; Smith, Joel B.; Wang, Gonghui; Jiang, Yao; Roering, Joshua J.

    2018-01-01

    Largely unknown mechanisms restrain motion of clay-rich, slow-moving landslides that are widespread worldwide and rarely accelerate catastrophically. We studied a clayey, slow-moving landslide typical of thousands in northern California, USA, to decipher hydrologic-mechanical interactions that modulate landslide dynamics. Similar to some other studies, observed pore-water pressures correlated poorly with landslide reactivation and speed. In situ and laboratory measurements strongly suggested that variable pressure along the landslide's lateral shear boundaries resulting from seasonal soil expansion and contraction modulated its reactivation and speed. Slope-stability modeling suggested that the landslide's observed behavior could be predicted by including transient swell pressure as a resistance term, whereas modeling considering only transient hydrologic conditions predicted movement 5–6 months prior to when it was observed. All clayey soils swell to some degree; hence, our findings suggest that swell pressure likely modulates motion of many landslides and should be considered to improve forecasts of clayey landslide initiation and mobility.

  10. Rhythmic components in renal autoregulation: Nonlinear modulation phenomena

    International Nuclear Information System (INIS)

    Pavlov, A.N.; Sosnovtseva, O.V.; Pavlova, O.N.; Mosekilde, E.; Holstein-Rathlou, N.-H.

    2009-01-01

    Autoregulation of nephron blood flow involves two oscillatory processes: the tubular-flow sensitive tubuloglomerular feedback (TGF) mechanism and the blood-pressure sensitive myogenic mechanism. Both act to regulate the diameter of the afferent arteriole, which carries blood to the nephron. In this paper, we apply wavelet analysis to time series of the proximal tubular pressure obtained from normotensive and hypertensive rats to study how the TGF-mediated oscillations modulate both the frequency and the amplitude of the myogenic oscillations. The tubular pressure oscillations are nearly periodic for normotensive rats, but irregular (or chaotic) for rats with hypertension. Modulation phenomena are clearly observed in both types of rats, but the effect is stronger in those with hypertension.

  11. Liquid crystalline fiber optic colorimeter for hydrostatic pressure measurement

    Science.gov (United States)

    Wolinski, Tomasz R.; Bajdecki, Waldemar K.; Domanski, Andrzej W.; Karpierz, Miroslaw A.; Konopka, Witold; Nasilowski, T.; Sierakowski, Marek W.; Swillo, Marcin; Dabrowski, Roman S.; Nowinowski-Kruszelnicki, Edward; Wasowski, Janusz

    2001-08-01

    This paper presents results of tests performed on a fiber optic system of liquid crystalline transducer for hydrostatic pressure monitoring based on properties of colorimetry. The system employs pressure-induced deformations occurring in liquid crystalline (LC) cells configured in a homogeneous Frederiks geometry. The sensor is compared of a round LC cell placed inside a specially designed pressure chamber. As a light source we used a typical diode operating at red wavelength and modulated using standard techniques. The pressure transducer was connected to a computer with a specially designed interface built on the bas of advanced ADAM modules. Results indicate that the system offers high response to pressure with reduced temperature sensitivity and, depending on the LC cell used, can be adjusted for monitoring of low hydrostatic pressures up to 6 MPa. These studies have demonstrated the feasibility of fiber optic liquid crystal colorimeter for hydrostatic pressure sensing specially dedicated to pipe- lines, mining instrumentation, and process-control technologies.

  12. Wavelength modulation spectroscopy near 5 μm for carbon monoxide sensing in a high-pressure kerosene-fueled liquid rocket combustor

    Science.gov (United States)

    Lee, Daniel D.; Bendana, Fabio A.; Schumaker, S. Alexander; Spearrin, R. Mitchell

    2018-05-01

    A laser absorption sensor was developed for carbon monoxide (CO) sensing in high-pressure, fuel-rich combustion gases associated with the internal conditions of hydrocarbon-fueled liquid bipropellant rockets. An absorption feature near 4.98 μm, comprised primarily of two rovibrational lines from the P-branch of the fundamental band, was selected to minimize temperature sensitivity and spectral interference with other combustion gas species at the extreme temperatures (> 3000 K) and pressures (> 50 atm) in the combustion chamber environment. A scanned wavelength modulation spectroscopy technique (1 f-normalized 2 f detection) is utilized to infer species concentration from CO absorption, and mitigate the influence of non-absorption transmission losses and noise associated with the harsh sooting combustor environment. To implement the sensing strategy, a continuous-wave distributed-feedback (DFB) quantum cascade laser (QCL) was coupled to a hollow-core optical fiber for remote mid-infrared light delivery to the test article, with high-bandwidth light detection by a direct-mounted photovoltaic detector. The method was demonstrated to measure time-resolved CO mole fraction over a range of oxidizer-to-fuel ratios and pressures (20-70 atm) in a single-element-injector RP-2-GOx rocket combustor.

  13. Spin Forming Aluminum Crew Module (CM) Metallic Aft Pressure Vessel Bulkhead (APVBH) - Phase II

    Science.gov (United States)

    Hoffman, Eric K.; Domack, Marcia S.; Torres, Pablo D.; McGill, Preston B.; Tayon, Wesley A.; Bennett, Jay E.; Murphy, Joseph T.

    2015-01-01

    The principal focus of this project was to assist the Multi-Purpose Crew Vehicle (MPCV) Program in developing a spin forming fabrication process for manufacture of the Orion crew module (CM) aft pressure vessel bulkhead. The spin forming process will enable a single piece aluminum (Al) alloy 2219 aft bulkhead resulting in the elimination of the current multiple piece welded construction, simplify CM fabrication, and lead to an enhanced design. Phase I (NASA TM-2014-218163 (1)) of this assessment explored spin forming the single-piece CM forward pressure vessel bulkhead. The Orion MPCV Program and Lockheed Martin (LM) recently made two critical decisions relative to the NESC Phase I work scope: (1) LM selected the spin forming process to manufacture a single-piece aft bulkhead for the Orion CM, and (2) the aft bulkhead will be manufactured from Al 2219. Based on the Program's new emphasis related to the spin forming process, the NESC was asked to conduct a Phase II assessment to assist in the LM manufacture of the aft bulkhead and to conduct a feasibility study into spin forming the Orion CM cone. This activity was approved on June 19, 2013. Dr. Robert Piascik, NASA Technical Fellow for Materials at the Langley Research Center (LaRC), was selected to lead this assessment. The project plan was approved by the NASA Engineering and Safety Center (NESC) Review Board (NRB) on July 18, 2013. The primary stakeholders for this assessment were the NASA and LM MPCV Program offices. Additional benefactors are commercial launch providers developing CM concepts.

  14. Supercritical water gasification with decoupled pressure and heat transfer modules

    KAUST Repository

    Dibble, Robert W.; Ng, Kim Choon; Sarathy, Mani

    2017-01-01

    decouples the function of containing high pressure from the high temperature function. The present invention allows the heat transfer function to be conducted independently from the pressure transfer function such that the system equipment can be designed

  15. Molecular density modulation type ultrahigh vacuum gauge

    International Nuclear Information System (INIS)

    Horikoshi, Gen-ichi; Komada, Kazutaka; Mizuno, Hajime

    1978-01-01

    When pressure is measured in ultrahigh vacuum region, with an ionization gauge one of the causes producing the measuring limit is its dark current due to so-called soft X-ray effect and ion desorption. A kind of the modulation gauge provided with a modulation electrode is described in this paper. If a plate is vibrating perpendicularly to its surface in the sufficiently low pressure gas to satisfy molecular conditions (molecular density n), the molecular density in the space in front of the plate is expected to vary with time, affected by the vibration of the plate. When the vacuum gauge is placed in this space, the modulated current is proportional to pressure P, which is not related to the current due to soft X-ray effect and ion desorption. The other cause of determining the pressure-measuring limit is noises, among which only the noise coherent with the vibration of the plate affects the measurement. To avoid the induced current by this type of noise, it is considered to use the pulse-counting technique using an electron multiplier. It is anticipated that the induced currents generated from electrical noises and mechanical vibrations can be avoided almost completely by this method. As a result, the theoretical measuring limit may be estimated at approximately 5 x 10 -13 Torr, if the mean residence time in the collision of molecules with the plate is assumed to be 1 sec, the sensitivity of the vacuum gauge S is 20 Torr -1 , electron current Ie is 2 x 10 -3 A and modulation coefficient m is 3 x 10 -3 . (Wakatsuki, Y.)

  16. Application of the FADS system on the Re-entry Module

    Science.gov (United States)

    Zhen, Huang

    2016-07-01

    The aerodynamic model for Flush Air Data Sensing System (FADS) is built based on the surface pressure distribution obtained through the pressure orifices laid on specific positions of the surface,and the flight parameters,such as angle of attack,angle of side-slip,Mach number,free-stream static pressure and dynamic pressure are inferred from the aerodynamic model.The flush air data sensing system (FADS) has been used on several flight tests of aircraft and re-entry vehicle,such as,X-15,space shuttle,F-14,X-33,X-43A and so on. This paper discusses the application of the FADS on the re-entry module with blunt body to obtain high-precision aerodynamic parameters.First of all,a basic theory and operating principle of the FADS is shown.Then,the applications of the FADS on typical aircrafts and re-entry vehicles are described.Thirdly,the application mode on the re-entry module with blunt body is discussed in detail,including aerodynamic simulation,pressure distribution,trajectory reconstruction and the hardware shoule be used,such as flush air data sensing system(FADS),inertial navigation system (INS),data acquisition system,data storage system.Finally,ablunt module re-entry flight test from low earth orbit (LEO) is planned to obtain aerodynamic parameters and amend the aerodynamic model with this FADS system data.The results show that FADS system can be applied widely in re-entry module with blunt bodies.

  17. Fixed field alternating gradient accelerator with small orbit shift and tune excursion

    Directory of Open Access Journals (Sweden)

    Suzanne L. Sheehy

    2010-04-01

    Full Text Available A new design principle of a nonscaling fixed field alternating gradient accelerator is proposed. It is based on optics that produce approximate scaling properties. A large field index k is chosen to squeeze the orbit shift as much as possible by setting the betatron oscillation frequency in the second stability region of Hill’s equation. Then, the lattice magnets and their alignment are simplified. To simplify the magnets, we expand the field profile of r^{k} into multipoles and keep only a few lower order terms. A rectangular-shaped magnet is assumed with lines of constant field parallel to the magnet axis. The lattice employs a triplet of rectangular magnets for focusing, which are parallel to one another to simplify alignment. These simplifications along with fringe fields introduce finite chromaticity and the fixed field alternating gradient accelerator is no longer a scaling one. However, the tune excursion of the whole ring can be within half an integer and we avoid the crossing of strong resonances.

  18. Analysis of fission product release from HTGR core during transient temperature excursion

    International Nuclear Information System (INIS)

    Saito, Takao; Yamatoya, Naotoshi; Onuma, Mamoru

    1978-01-01

    The computer program ''FRANC'' was developed to calculate the release activity of fission products from a high-temperature gas cooled reactor (HTGR) core during transient temperature excursions such as a hypothetical loss of forced circulation combined with design basis depressurization. The program utilizes a segmented cylindrical core spatial model with the associated values of the prior fuel irradiation history and temperature conditions. The fission product transport and decay chain behavior is expressed by a set of differential equations. This set of equations describes the entire core inventory of fission products by means of calculated parameters based on the detailed spatial core conditions. The program determines the time-dependent amounts of fission product nuclides escaping from the core into the coolant. Coded in Continuous System Simulation Language (CSSL) with double precision, FRANC showed appropriate results for both short- and long-lived fission product nuclides. The sample calculation conducted by applying the program to a large HTGR indicated that it would take about one hour for noble gases and volatile nuclides to be released to the coolant, and several hours for metalic nuclides. (auth.)

  19. Monolithic Composite “Pressure + Acceleration + Temperature + Infrared” Sensor Using a Versatile Single-Sided “SiN/Poly-Si/Al” Process-Module

    Directory of Open Access Journals (Sweden)

    Xinxin Li

    2013-01-01

    Full Text Available We report a newly developed design/fabrication module with low-cost single-sided “low-stress-silicon-nitride (LS-SiN/polysilicon (poly-Si/Al” process for monolithic integration of composite sensors for sensing-network-node applications. A front-side surface-/bulk-micromachining process on a conventional Si-substrate is developed, featuring a multifunctional SiN/poly-Si/Al layer design for diverse sensing functions. The first “pressure + acceleration + temperature + infrared” (PATIR composite sensor with the chip size of 2.5 mm × 2.5 mm is demonstrated. Systematic theoretical design and analysis methods are developed. The diverse sensing components include a piezoresistive absolute-pressure sensor (up to 700 kPa, with a sensitivity of 49 mV/MPa under 3.3 V supplied voltage, a piezoresistive accelerometer (±10 g, with a sensitivity of 66 μV/g under 3.3 V and a −3 dB bandwidth of 780 Hz, a thermoelectric infrared detector (with a responsivity of 45 V/W and detectivity of 3.6 × 107 cm·Hz1/2/W and a thermistor (−25–120 °C. This design/fabrication module concept enables a low-cost monolithically-integrated “multifunctional-library” technique. It can be utilized as a customizable tool for versatile application-specific requirements, which is very useful for small-size, low-cost, large-scale sensing-network node developments.

  20. Pressure modulates the self-cleavage step of the hairpin ribozyme

    Science.gov (United States)

    Schuabb, Caroline; Kumar, Narendra; Pataraia, Salome; Marx, Dominik; Winter, Roland

    2017-03-01

    The ability of certain RNAs, denoted as ribozymes, to not only store genetic information but also catalyse chemical reactions gave support to the RNA world hypothesis as a putative step in the development of early life on Earth. This, however, might have evolved under extreme environmental conditions, including the deep sea with pressures in the kbar regime. Here we study pressure-induced effects on the self-cleavage of hairpin ribozyme by following structural changes in real-time. Our results suggest that compression of the ribozyme leads to an accelerated transesterification reaction, being the self-cleavage step, although the overall process is retarded in the high-pressure regime. The results reveal that favourable interactions between the reaction site and neighbouring nucleobases are strengthened under pressure, resulting therefore in an accelerated self-cleavage step upon compression. These results suggest that properly engineered ribozymes may also act as piezophilic biocatalysts in addition to their hitherto known properties.

  1. Experimental and numerical studies on pressure drop in reverse electrodialysis: Effect of unit cell configuration

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Sung Kook; Choi, Kyung Soo [Advanced Combustion Laboratory, Korea Institute of Energy Research, Daejeon (Korea, Republic of); Kim, Chan Soo; Hwang, Kyo Sik; Han, Ji Hyung; Kim, Han Ki; Jeong, Nam Jo [Jeju Global Research Center, Korea Institute of Energy Research, Jeju (Korea, Republic of)

    2016-11-15

    Experimental and numerical studies on pressure drop in Reverse electrodialysis (RED) were performed. In this study, a module with 200 unit cells is considered for the demonstration of bench-scale RED module and two different unit cell configurations are utilized. Pressure drop through the module is measured by varying flow rates. For evaluating the hydrodynamic characteristics in the unit cell, a numerical simulation is also conducted and the simplified method using a porous media model is employed to simulate the channel filled with spacer. Due to the insertion of spacer and narrow channel, great pressure loss occurs along the unit cell. Based on estimated pressure data, high pressure difference between seawater and fresh water channel takes place locally in the unit cell configuration with crossflow direction, leading to a leakage problem through the membrane and finally degradation in the output power. Consequently, it is confirmed that the unit cell configuration is one of the important design parameters in a RED module.

  2. Rhythmic components in renal autoregulation: Nonlinear modulation phenomena

    DEFF Research Database (Denmark)

    Pavlov, A. N.; Sosnovtseva, Olga; Pavlova, O. N.

    2009-01-01

    . In this paper, we apply wavelet analysis to time series of the proximal tubular pressure obtained from normotensive and hypertensive rats to study how the TGF-mediated oscillations modulate both the frequency and the amplitude of the myogenic oscillations. The tubular pressure oscillations are nearly periodic...

  3. The use of genetic programming to develop a predictor of swash excursion on sandy beaches

    Science.gov (United States)

    Passarella, Marinella; Goldstein, Evan B.; De Muro, Sandro; Coco, Giovanni

    2018-02-01

    We use genetic programming (GP), a type of machine learning (ML) approach, to predict the total and infragravity swash excursion using previously published data sets that have been used extensively in swash prediction studies. Three previously published works with a range of new conditions are added to this data set to extend the range of measured swash conditions. Using this newly compiled data set we demonstrate that a ML approach can reduce the prediction errors compared to well-established parameterizations and therefore it may improve coastal hazards assessment (e.g. coastal inundation). Predictors obtained using GP can also be physically sound and replicate the functionality and dependencies of previous published formulas. Overall, we show that ML techniques are capable of both improving predictability (compared to classical regression approaches) and providing physical insight into coastal processes.

  4. Laryngeal and phrenic nerve involvement in a patient with hereditary neuropathy with liability to pressure palsies (HNPP).

    Science.gov (United States)

    Cortese, A; Piccolo, G; Lozza, A; Schreiber, A; Callegari, I; Moglia, A; Alfonsi, E; Pareyson, D

    2016-07-01

    Lower cranial and phrenic nerve involvement is exceptional in hereditary neuropathy with liability to pressure palsies (HNPP). Here we report the occurrence of reversible laryngeal and phrenic nerve involvement in a patient with HNPP. The patient recalled several episodes of reversible weakness and numbness of his feet and hands since the age of 30 years. His medical history was uneventful, apart from chronic obstructive pulmonary disease (COPD). At age 44, following severe weight loss, he presented with progressive dysphonia and hoarseness. EMG of cricoarytenoid and thyroarytenoid muscles and laryngeal fibroscopy confirmed vocal cord paralysis. These speech disturbances gradually regressed. Two years later, he reported rapidly worsening dyspnea. Electroneurography showed increased distal latency of the right phrenic nerve and diaphragm ultrasonography documented reduced right hemi-diaphragm excursion. Six months later and after optimization of CODP treatment, his respiratory function had improved and both phrenic nerve conduction and diaphragm excursion were completely restored. We hypothesize that chronic cough and nerve stretching in the context of CODP, together with severe weight loss, may have triggered the nerve paralysis in this patient. Our report highlights the need for optimal management of comorbidities such as CODP as well as careful control of weight in HNPP patients to avoid potentially harmful complications. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. Increased vascular sympathetic modulation in mice with Mas receptor deficiency

    Science.gov (United States)

    Rabello Casali, Karina; Ravizzoni Dartora, Daniela; Moura, Marina; Bertagnolli, Mariane; Bader, Michael; Haibara, Andrea; Alenina, Natalia; Irigoyen, Maria Claudia; Santos, Robson A

    2016-01-01

    Introduction: The angiotensin-converting enzyme 2 (ACE2)/angiotensin (Ang)-(1–7)/Mas axis could modulate the heart rate (HR) and blood pressure variabilities (BPV) which are important predictors of cardiovascular risk and provide information about the autonomic modulation of the cardiovascular system. Therefore we investigated the effect of Mas deficiency on autonomic modulation in wild type and Mas-knockout (KO) mice. Methods: Blood pressure was recorded at high sample rate (4000 Hz). Stationary sequences of 200–250 beats were randomly chosen. Frequency domain analysis of HR and BPV was performed with an autoregressive algorithm on the pulse interval sequences and on respective systolic sequences. Results: The KO group presented an increase of systolic arterial pressure (SAP; 127.26±11.20 vs 135.07±6.98 mmHg), BPV (3.54±1.54 vs 5.87±2.12 mmHg2), and low-frequency component of systolic BPV (0.12±0.11 vs 0.47±0.34 mmHg2). Conclusions: The deletion of Mas receptor is associated with an increase of SAP and with an increased BPV, indicating alterations in autonomic control. Increase of sympathetic vascular modulation in absence of Mas evidences the important role of Ang-(1–7)/Mas on cardiovascular regulation. Moreover, the absence of significant changes in HR and HRV can indicate an adaptation of autonomic cardiac balance. Our results suggest that the Ang-(1–7)/Mas axis seems more important in autonomic modulation of arterial pressure than HR. PMID:27080540

  6. Falsifying the Sikussak-Oasis Hypothesis for the Tillite Group, East Greenland: Implications for Trezona-like Carbon Isotope Excursions Beneath Neoproterozoic Glacials

    Science.gov (United States)

    Hoffman, P. F.; Domack, E. W.; Maloof, A. C.; Halverson, G. P.

    2006-05-01

    In Neoproterozoic time, East Greenland and East Svalbard (EGES) occupied landward and seaward positions, respectively, on the southern subtropical margin of Laurentia. In both areas, thick clastic-to-carbonate successions are overlain by two discrete glacial and/or periglacial formations, separated by fine basinal clastics. In Svalbard, the younger glacial has a characteristic Marinoan (basal Ediacaran) cap dolostone, but the older glacial is underlain by a 10-permil negative carbon isotope excursion that is indistinguishable from excursions observed exclusively beneath Marinoan glacials in Australia, Namibia and western Laurentia. This led us to propose (Basin Research 16, 297-324, 2004) that the paired glacials in EGES represent the onset and climax of a single, long-lived, Marinoan glaciation. The intervening fine clastics, which contain ikaite pseudomorphs, presumptively accumulated beneath permanent shorefast sea ice (sikussak), analogous to East Greenland fjords during the Younger Dryas and Little Ice Age. In this model, the top of the older glacial signals the start of Snowball Earth. We conducted a preliminary field test of the sikussak hypothesis in Strindberg Land (SL), Andrée Land (AL) and Ella O (EO), East Greenland. We confirmed the correlation of the paired glacials and the Marinoan cap dolostone (missing on EO). In SL, the older glacial (Ulveso Fm) is a thin diamictite overlain by conglomerate lag and a set of megavarves composed of alternating siltstone and ice-rafted debris. In AL and EO, the Ulveso is a sub-glacial diamictite overlain by aeolian and/or marine sandstone. In Bastion Bugt on EO, it is a transgressive shoreface sandstone. This proves that glacial recession occurred under open-water conditions and did not result from permanent sea-ice formation, as stipulated in the sikussak model. There is no evidence that the fine clastic sequence between the glacials formed under an ice cover, or for a single glacial period. This brings us back to

  7. High pressure effects on protein structure and function.

    Science.gov (United States)

    Mozhaev, V V; Heremans, K; Frank, J; Masson, P; Balny, C

    1996-01-01

    Many biochemists would regard pressure as a physical parameter mainly of theoretical interest and of rather limited value in experimental biochemistry. The goal of this overview is to show that pressure is a powerful tool for the study of proteins and modulation of enzymatic activity.

  8. Supercritical water gasification with decoupled pressure and heat transfer modules

    KAUST Repository

    Dibble, Robert

    2017-09-14

    The present invention discloses a system and method for supercritical water gasification (SCWG) of biomass materials wherein the system includes a SCWG reactor and a plurality of heat exchangers located within a shared pressurized vessel, which decouples the function of containing high pressure from the high temperature function. The present invention allows the heat transfer function to be conducted independently from the pressure transfer function such that the system equipment can be designed and fabricated in manner that would support commercial scaled-up SCWG operations. By using heat exchangers coupled to the reactor in a series configuration, significant efficiencies are achieved by the present invention SCWG system over prior known SCWG systems.

  9. Time-on-task decrement in vigilance is modulated by inter-individual vulnerability to homeostatic sleep pressure manipulation

    Directory of Open Access Journals (Sweden)

    Micheline eMaire

    2014-03-01

    Full Text Available Under sleep loss, vigilance is reduced and attentional failures emerge progressively. It becomes difficult to maintain stable performance over time, leading to growing performance variability (i.e. state instability in an individual and among subjects. Task duration plays a major role in the maintenance of stable vigilance levels, such that the longer the task, the more likely state instability will be observed. Vulnerability to sleep-loss-dependent performance decrements is highly individual and is also modulated by a polymorphism in the human clock gene PERIOD3 (PER3. By combining two different protocols, we manipulated sleep-wake history by once extending wakefulness for 40 h (high sleep pressure condition and once by imposing a short sleep-wake cycle by alternating 160 min of wakefulness and 80 min naps (low sleep pressure condition in a within-subject design. We observed that homozygous carriers of the long repeat allele of PER3 (PER35/5 experienced a greater time-on-task dependent performance decrement (i.e., a steeper increase in the number of lapses in the Psychomotor Vigilance Task compared to the carriers of the short repeat allele (PER34/4. These genotype-dependent effects disappeared under low sleep pressure conditions, and neither motivation, nor perceived effort accounted for these differences. Our data thus suggest that greater sleep-loss related attentional vulnerability based on the PER3 polymorphism is mirrored by a greater state instability under extended wakefulness in the short compared to the long allele carriers. Our results undermine the importance of time-on-task related aspects when investigating inter-individual differences in sleep loss-induced behavioural vulnerability.

  10. Cosmogenic signature of geomagnetic reversals and excursions from the Réunion event to the Matuyama-Brunhes transition (0.7-2.14 Ma interval)

    Science.gov (United States)

    Simon, Quentin; Bourlès, Didier L.; Thouveny, Nicolas; Horng, Chorng-Shern; Valet, Jean-Pierre; Bassinot, Franck; Choy, Sandrine

    2018-01-01

    Long-term variations of the geomagnetic dipole moment (GDM) during periods of stable polarity and in transitional states (reversals and excursions) provide key information for understanding the geodynamo regime. Following several studies dealing with the Brunhes chron and the Matuyama-Brunhes transition, this study presents a new authigenic 10Be/9Be ratio (Be-ratio) record obtained from the MD97-2143 core (western Pacific Ocean). This new Be-ratio series yields a record of GDM variations covering the early Brunhes and mid to late Matuyama time period (i.e. 700-2140 ka), independently from the relative paleointensity (RPI) record obtained from the same core, that can be compared with available RPI records and stacks. Stratigraphic offsets measured between the Be-ratio peaks and the corresponding RPI minima reach 2 to 14 cm. They can be assigned to (post-) detrital remanent magnetization (pDRM) effects leading to magnetization locking-in delays varying from 2 to 12 ka in the studied core. 10Be overproduction episodes triggered by geomagnetic dipole moment lows (GDL) linked to polarity reversals and excursions confirm the global control exerted by the GDM on cosmogenic radionuclides production. A dipole moment reconstruction derived from the Beryllium-10 (BeDiMo) was compiled and calibrated using absolute paleointensity data. This independent record complements the available paleomagnetic RPI records, permitting 1) to overcome the pDRM lock-in offsets induced below the mixing layer, 2) to confront and increase the robustness and precision of GDM reconstructions and, 3) to better constrain the chronology of geomagnetic field instabilities during the mid to late Matuyama chron. Our new 10Be derived inventory is fully compatible with the GDL series linked to geomagnetic polarity reversals and events (Matuyama-Brunhes transition, Jaramillo and Olduvai subchron boundaries, Cobb Mountain, Réunion) and it strengthens the occurrence of several excursions (Kamikatsura, Santa

  11. Experimental investigation of PV modules recycling; PV module recycle no jikkenteki kento

    Energy Technology Data Exchange (ETDEWEB)

    Unagida, H; Kurokawa, K [Tokyo University of Agriculture and Technology, Tokyo (Japan); Sakuta, K; Otani, K; Murata, K [Electrotechnical Laboratory, Tsukuba (Japan)

    1997-11-25

    Recycling, cost/energy analysis and recovery experiment were made on crystalline silicon PV modules with EVA(ethylene vinyl acetate)-laminated structure. The life of modules is dependent not on performance deterioration of PV cells themselves but on yellowing or poor transmittance of EVA caused by ultraviolet ray, and disconnection between cells by thermal stress. Recovery is carried out in 3 stages of cell, wafer and material. Recovery in the stages of cell and wafer results in considerable reduction of energy and cost. The recovery experiment was carried out using PV module samples prepared by cutting the modules into 25times15mm pieces after removing Al frames from the used modules, peeling back sheets and cutting off EVA. Since a nitric acid process at 70-80degC can dissolve EVA effectively, it is promising for reuse of surface glass and PV cells as they are. This process is also carried out under a condition around room temperature and pressure, contributing to cost reduction and energy saving for recycling. Generation of harmful NOx is only a problem to be solved. 2 refs., 6 figs., 1 tab.

  12. Perception of a Sung Vowel as a Function of Frequency-Modulation Rate and Excursion in Listeners with Normal Hearing and Hearing Impairment

    Science.gov (United States)

    Vatti, Marianna; Santurette, Sébastien; Pontoppidan, Niels Henrik; Dau, Torsten

    2014-01-01

    Purpose: Frequency fluctuations in human voices can usually be described as coherent frequency modulation (FM). As listeners with hearing impairment (HI listeners) are typically less sensitive to FM than listeners with normal hearing (NH listeners), this study investigated whether hearing loss affects the perception of a sung vowel based on FM…

  13. Hallux valgus and plantar pressure loading: the Framingham foot study

    Science.gov (United States)

    2013-01-01

    Background Hallux valgus (HV), a common structural foot deformity, can cause foot pain and lead to limited mobility. The purpose of this study was to evaluate differences in plantar pressure and force during gait by HV status in a large population-based cohort of men and women. Methods A trained examiner performed a validated physical examination on participants’ feet and recorded the presence of hallux valgus and other specific foot disorders. Each foot was classified into one of four mutually exclusive groups based on the foot examination. Foot groups were: (i) HV only, (ii) HV and at least one additional foot disorder (FD), (iii) no HV but at least one other FD, and (iv) neither HV nor FD (referent). Biomechanical data for both feet were collected using Tekscan Matscan. Foot posture during quiet standing, using modified arch index (MAI), and foot function during gait, using center of pressure excursion index (CPEI), were calculated per foot. Further, walking scans were masked into eight sub-regions using Novel Automask, and peak pressure and maximum force exerted in each region were calculated. Results There were 3205 participants, contributing 6393 feet with complete foot exam data and valid biomechanical measurements. Participants with HV had lower hallucal loading and higher forces at lesser toes as well as higher MAI and lower CPEI values compared to the referent. Participants with HV and other FDs were also noted to have aberrant rearfoot forces and pressures. Conclusions These results suggest that HV alters foot loading patterns and pressure profiles. Future work should investigate how these changes affect the risk of other foot and lower extremity ailments. PMID:24138804

  14. NpX3 compounds under high pressure

    International Nuclear Information System (INIS)

    Zwirner, S.; Kalvius, G.M.

    1993-01-01

    The systematics of hyperfine interactions and the ordering temperature T ord in isostructural NpX 3 compounds (X=Al, Si, Ga, Ge, ln, Sn) are briefly reviewed. NpSn 3 has been viewed as a Kondo lattice system, similar to CeAl 2 , NpIn 3 shows a modulated magnetic structure including low moment and nonmagnetic contributions at ambient pressure and 4.2 K. Preliminary results of recent 237 Np Moessbauer studies on NpIn 3 at ambient pressure and various temperatures and at 4.0(8) GPa and 4.2 K are reported. At 4.0(8) GPa, T ord rises from 17 to 22 K, the low-moment contributions of the modulated structure are reduced and the non-magnetic site is lost below T ord . The variation of the hyperfine parameters and of T ord with pressure is similar to the behavior observed in NpSn 3 . (orig.)

  15. The use of genetic programming to develop a predictor of swash excursion on sandy beaches

    Directory of Open Access Journals (Sweden)

    M. Passarella

    2018-02-01

    Full Text Available We use genetic programming (GP, a type of machine learning (ML approach, to predict the total and infragravity swash excursion using previously published data sets that have been used extensively in swash prediction studies. Three previously published works with a range of new conditions are added to this data set to extend the range of measured swash conditions. Using this newly compiled data set we demonstrate that a ML approach can reduce the prediction errors compared to well-established parameterizations and therefore it may improve coastal hazards assessment (e.g. coastal inundation. Predictors obtained using GP can also be physically sound and replicate the functionality and dependencies of previous published formulas. Overall, we show that ML techniques are capable of both improving predictability (compared to classical regression approaches and providing physical insight into coastal processes.

  16. Self-initialization module for the RELAP4/MOD7 program

    International Nuclear Information System (INIS)

    Behling, S.R.; Burgess, C.H.; Johnsen, G.W.

    1979-01-01

    An automated self-initialization option has been developed and implemented into the RELAP4/MOD7 computer code. With this new feature, pressurized water reactors or similar models may be initialized to steady state conditions with minimal user-supplied input data. Previously, the analyst (user) had to hand compute all pressures and temperatures in conjunction with several iterative computer runs. Two semi-independent functions, pressure balancing and thermal balancing, comprise the self-initialization module. The user supplies input data specifying a reference pressure and temperature and associated locations. Control volume pressures and temperatures are computed consistent with the nodalization, geometry, total power, and mass flow rates specified. Verification has been accomplished by performing transient calculations on system models and observing the persistence of stable operating conditions. Preparation of input data for the self-initialization module seldom requires more than several man-hours. Computing time required on a CDC 7600 computer to complete the self-initialization process is typically less than 30 seconds

  17. In search of mitochondrial mechanisms: interfield excursions between cell biology and biochemistry.

    Science.gov (United States)

    Bechtel, William; Abrahamsen, Adele

    2007-01-01

    Developing models of biological mechanisms, such as those involved in respiration in cells, often requires collaborative effort drawing upon techniques developed and information generated in different disciplines. Biochemists in the early decades of the 20th century uncovered all but the most elusive chemical operations involved in cellular respiration, but were unable to align the reaction pathways with particular structures in the cell. During the period 1940-1965 cell biology was emerging as a new discipline and made distinctive contributions to understanding the role of the mitochondrion and its component parts in cellular respiration. In particular, by developing techniques for localizing enzymes or enzyme systems in specific cellular components, cell biologists provided crucial information about the organized structures in which the biochemical reactions occurred. Although the idea that biochemical operations are intimately related to and depend on cell structures was at odds with the then-dominant emphasis on systems of soluble enzymes in biochemistry, a reconceptualization of energetic processes in the 1960s and 1970s made it clear why cell structure was critical to the biochemical account. This paper examines how numerous excursions between biochemistry and cell biology contributed a new understanding of the mechanism of cellular respiration.

  18. On the importance of valve modelling, reflected pressures, and wall friction, in CATHENA water hammer simulations

    International Nuclear Information System (INIS)

    Beuthe, T.G.

    1998-01-01

    The results of code and modelling developments outlined in this paper show that CATHENA can be used to accurately model the behaviour of valve slam generated water hammer if sufficient care and detail are used to model the characteristics of the valve. It also shows that CATHENA can accurately predict the reflection and transmission of travelling water pressure waves at expansions, contractions, and dead ends. Finally, although CATHENA is capable of accurately predicting the critical phenomena observed in water hammer, the inter-peak timing of the pressure excursions is not well predicted when significant bulk flows occur. The use of an unsteady wall friction factor to correct for this discrepancy has been examined, but the implementation of relationships suggested in the literature provided too much damping. A good match between experimental and simulation data can be achieved, but it is suggested that the default implementation of such a relationship take place only after an investigation of further potential loss terms can be completed. (author)

  19. High pressure and [Ca2+] produce an inverse modulation of synaptic input strength, network excitability and frequency response in the rat dentate gyrus

    Directory of Open Access Journals (Sweden)

    Thomas I Talpalar

    2016-09-01

    Full Text Available Hyperbaric environments induce the high pressure neurological syndrome (HPNS characterized by hyperexcitability of the central nervous system and memory impairment. Human divers and other animals experience the HPNS at pressures beyond 1.1 MPa. High pressure depresses synaptic transmission and alters its dynamics in various animal models. Medial perforant path (MPP synapses connecting the medial entorhinal cortex with the hippocampal formation are suppressed by 50% at 10.1MPa. Reduction of synaptic inputs is paradoxically associated with enhanced ability of dentate gyrus’ granule cells to generate spikes at high pressure. This mechanism allows MPP inputs to elicit standard granule cell outputs at 0.1 -25 Hz frequencies under hyperbaric conditions. An increased postsynaptic gain of MPP inputs probably allows diving animals to perform in hyperbaric environments, but makes them vulnerable to high intensity/frequency stimuli producing hyperexcitability. Increasing extracellular Ca2+ (Ca2+o partially reverted pressure-mediated depression of MPP inputs and increased MPP’s low-pass filter properties. We postulated that raising Ca2+o in addition to increase synaptic inputs may reduce network excitability in the dentate gyrus potentially improving its function and reducing sensitivity to high intensity and pathologic stimuli. For this matter, we activated the MPP with single and 50 Hz frequency stimuli that simulated physiologic and deleterious conditions, while assessing the granule cell’s output under various conditions of pressure and Ca2+o. Our results reveal that pressure and Ca2+o produce an inverse modulation on synaptic input strength and network excitability. These coincident phenomena suggest a potential general mechanism of networks that adjusts gain as an inverse function of synaptic inputs’ strength. Such mechanism may serve for adaptation to variable pressure and other physiological and pathological conditions and may explain the

  20. Sensitivity analysis of power excursion in RSG-GAS reactor due to reactivity insertion

    International Nuclear Information System (INIS)

    Pinem, Surian; Sembiring, Tagor Malem

    2002-01-01

    Reactor kinetics has a very important role in reactor operation safety and nuclear reactor control. One of the important aspects in reactor kinetics is power behavior as function of time due to chain reaction in the core. The calculation was performed using kinetic equation and feedback reactivity and evaluated using static power coefficient. Analysis was performed for oxide 250 g, silicide 250 g and silicide 300 g fuel elements with insertion of positive reactivity, negative reactivity and reactivity close to delay neutron fraction. The calculation of power excursion sensitivity showed that the insertion of 0,5 % Δk/k, in the fuel element of silicide 300 g is bigger 5 % than the one of oxide 250 g or silicide 250 g. If inserted by - 1,2 % Δk/k, there is no change among three fuel elements. Therefore, in kinetic point of view, it is showed there is no significant influence in the RSG-GAS reactor operation safety is the current core of oxide 250 g is converted to silicide 250 g or to silicide 300 g

  1. High pressure modulated transport and signaling functions of membrane proteins in models and in vivo

    International Nuclear Information System (INIS)

    Vogel, R F; Linke, K; Teichert, H; Ehrmann, M A

    2008-01-01

    Cellular membranes serve in the separation of compartments, recognition of the environment, selective transport and signal transduction. Membrane lipids and membrane proteins play distinct roles in these processes, which are affected by environmental chemical (e. g. pH) or physical (e. g. pressure and temperature) changes. High hydrostatic pressure (HHP) affects fluidity and integrity of bacterial membranes instantly during the ramp, resulting in a loss of membrane potential and vital membrane protein functions. We have used the multiple drug transporter LmrA from Lactococcus lactis and ToxR, a membrane protein sensor from Photobacterium profundum, a deep-sea bacterium, and Vibrio cholerae to study membrane protein interaction and functionality in proteolioposomes and by the use of in vivo reporter systems, respectively. Both proteins require dimerization in the phospholipid bilayer for their functionality, which was favoured in the liquid crystalline lipid phase with ToxR and LmrA. Whereas LmrA, which resides in liposomes consisting of DMPC, DMPC/cholesterol or natural lipids, lost its ATPase activity above 20 or 40 MPa, it maintained its active dimeric structure in DOPC/DPPC/cholesterol liposomes up to 120 MPa. By using a specific indicator strain in which the dimerisation of ToxR initiates the transcription of lacZ it was demonstrated, that the amino acid sequence of the transmembrane domain influences HHP stability of ToxR dimerization in vivo. Thus, both the lipid structure and the nature of the protein affect membrane protein interaction. It is suggested that the protein structure determines basic functionality, e.g. principle ability or kinetics to dimerize to a functional complex, while the lipid environment modulates this property

  2. High pressure modulated transport and signaling functions of membrane proteins in models and in vivo

    Energy Technology Data Exchange (ETDEWEB)

    Vogel, R F; Linke, K; Teichert, H; Ehrmann, M A [Technische Universitaet Muenchen, Technische Mikrobiologie, Weihenstephaner Steig 16, 85350 Freising (Germany)], E-mail: rudi.vogel@wzw.tum.de

    2008-07-15

    Cellular membranes serve in the separation of compartments, recognition of the environment, selective transport and signal transduction. Membrane lipids and membrane proteins play distinct roles in these processes, which are affected by environmental chemical (e. g. pH) or physical (e. g. pressure and temperature) changes. High hydrostatic pressure (HHP) affects fluidity and integrity of bacterial membranes instantly during the ramp, resulting in a loss of membrane potential and vital membrane protein functions. We have used the multiple drug transporter LmrA from Lactococcus lactis and ToxR, a membrane protein sensor from Photobacterium profundum, a deep-sea bacterium, and Vibrio cholerae to study membrane protein interaction and functionality in proteolioposomes and by the use of in vivo reporter systems, respectively. Both proteins require dimerization in the phospholipid bilayer for their functionality, which was favoured in the liquid crystalline lipid phase with ToxR and LmrA. Whereas LmrA, which resides in liposomes consisting of DMPC, DMPC/cholesterol or natural lipids, lost its ATPase activity above 20 or 40 MPa, it maintained its active dimeric structure in DOPC/DPPC/cholesterol liposomes up to 120 MPa. By using a specific indicator strain in which the dimerisation of ToxR initiates the transcription of lacZ it was demonstrated, that the amino acid sequence of the transmembrane domain influences HHP stability of ToxR dimerization in vivo. Thus, both the lipid structure and the nature of the protein affect membrane protein interaction. It is suggested that the protein structure determines basic functionality, e.g. principle ability or kinetics to dimerize to a functional complex, while the lipid environment modulates this property.

  3. High pressure modulated transport and signaling functions of membrane proteins in models and in vivo

    Science.gov (United States)

    Vogel, R. F.; Linke, K.; Teichert, H.; Ehrmann, M. A.

    2008-07-01

    Cellular membranes serve in the separation of compartments, recognition of the environment, selective transport and signal transduction. Membrane lipids and membrane proteins play distinct roles in these processes, which are affected by environmental chemical (e. g. pH) or physical (e. g. pressure and temperature) changes. High hydrostatic pressure (HHP) affects fluidity and integrity of bacterial membranes instantly during the ramp, resulting in a loss of membrane potential and vital membrane protein functions. We have used the multiple drug transporter LmrA from Lactococcus lactis and ToxR, a membrane protein sensor from Photobacterium profundum, a deep-sea bacterium, and Vibrio cholerae to study membrane protein interaction and functionality in proteolioposomes and by the use of in vivo reporter systems, respectively. Both proteins require dimerization in the phospholipid bilayer for their functionality, which was favoured in the liquid crystalline lipid phase with ToxR and LmrA. Whereas LmrA, which resides in liposomes consisting of DMPC, DMPC/cholesterol or natural lipids, lost its ATPase activity above 20 or 40 MPa, it maintained its active dimeric structure in DOPC/DPPC/cholesterol liposomes up to 120 MPa. By using a specific indicator strain in which the dimerisation of ToxR initiates the transcription of lacZ it was demonstrated, that the amino acid sequence of the transmembrane domain influences HHP stability of ToxR dimerization in vivo. Thus, both the lipid structure and the nature of the protein affect membrane protein interaction. It is suggested that the protein structure determines basic functionality, e.g. principle ability or kinetics to dimerize to a functional complex, while the lipid environment modulates this property.

  4. Temporally resolved ozone distribution of a time modulated RF atmospheric pressure argon plasma jet: flow, chemical reaction, and transient vortex

    International Nuclear Information System (INIS)

    Zhang, S; Sobota, A; Van Veldhuizen, E M; Bruggeman, P J

    2015-01-01

    The ozone density distribution in the effluent of a time modulated RF atmospheric pressure plasma jet (APPJ) is investigated by time and spatially resolved by UV absorption spectroscopy. The plasma jet is operated with an averaged dissipated power of 6.5 W and gas flow rate 2 slm argon  +2% O 2 . The modulation frequency of the RF power is 50 Hz with a duty cycle of 50%. To investigate the production and destruction mechanism of ozone in the plasma effluent, the atomic oxygen and gas temperature is also obtained by TALIF and Rayleigh scattering, respectively. A temporal increase in ozone density is observed close to the quartz tube exit when the plasma is switched off due to the decrease in O density and gas temperature. Ozone absorption at different axial positions indicates that the ozone distribution is dominated by the convection induced by the gas flow and allows estimating the on-axis local gas velocity in the jet effluent. Transient vortex structures occurring during the switch on and off of the RF power also significantly affect the ozone density in the far effluent. (paper)

  5. Geological setting of the Olkiluoto investigation site, Eurajoki, SW Finland. Excursion guidebook

    International Nuclear Information System (INIS)

    Paulamaeki, S.

    2009-08-01

    -1250 million years in age. Their geochemical features suggest that they are feeder channels to continental flood basalts, which have not, however, been preserved in the Satakunta area. Lake Saeaeksjaervi, northeast of the Satakunta sandstone, hosts approximately 4.5 km wide impact structure of early Cambrian age (ca. 560 Ma). Below water level it contains unexposed suevite breccia and impact melt breccia. Day 1 of the field excursion introduces the Palaeoproterozoic geology of the Olkiluoto site, with special emphasis to the structural geology. Day 2 presents the Mesoproterozoic history of southern Satakunta area, including the Laitila and Eurajoki rapakivi granites, the Satakunta sandstone and the olivine diabases. The excursion ends to the Lake Saeaeksjaervi, where boulders of impact rocks can be found on the northern shore of the lake. (orig.)

  6. Significant intra-valvular pressure loss across EPIC SUPRA and perimount magna supra-annular designed aortic bioprostheses in patients with normal aortic size

    Directory of Open Access Journals (Sweden)

    Jagdish C. Mohan

    2017-01-01

    Full Text Available Doppler-derived trans-prosthetic gradients are higher and the estimated effective valve area is smaller than the catheter-derived and directly measured hemodynamic values, mostly due to pressure recovery phenomenon. Pressure recovery to a varying extent is common to all prosthetic heart valves including bioprostheses. Pressure recovery-related differences are usually small except in patients with bileaflet metallic prosthesis, wherein high-pressure local jets across central orifice have been documented since long back and also in patients with narrow aortic root. We describe two patients with normally functioning stented aortic bioprostheses with supra-annular design (EPIC SUPRA and PERIMOUNT MAGNA, wherein very high trans-prosthetic gradients and critically reduced estimated effective valve orifice areas in presence of normal aortic size were consistently recorded over long periods of follow-up. The valve leaflets, however had normal excursion, were thin, opened with a triangular or oblong shape and had expected geometric valve area (1.7 and 1.6 cm2 respectively measured by 3D trans-oesophageal echocardiographic planimetry. Pressure recovery upstream the valves accounted for 20% and 12% of total pressure gradients respectively. Dominant site for pressure drop was intra-valvular (75–85%. Such a phenomenon has not been reported in vivo for these two valve designs.

  7. Significant intra-valvular pressure loss across EPIC SUPRA and perimount magna supra-annular designed aortic bioprostheses in patients with normal aortic size.

    Science.gov (United States)

    Mohan, Jagdish C; Mohan, Vishwas; Shukla, Madhu; Sethi, Arvind

    Doppler-derived trans-prosthetic gradients are higher and the estimated effective valve area is smaller than the catheter-derived and directly measured hemodynamic values, mostly due to pressure recovery phenomenon. Pressure recovery to a varying extent is common to all prosthetic heart valves including bioprostheses. Pressure recovery-related differences are usually small except in patients with bileaflet metallic prosthesis, wherein high-pressure local jets across central orifice have been documented since long back and also in patients with narrow aortic root. We describe two patients with normally functioning stented aortic bioprostheses with supra-annular design (EPIC SUPRA and PERIMOUNT MAGNA), wherein very high trans-prosthetic gradients and critically reduced estimated effective valve orifice areas in presence of normal aortic size were consistently recorded over long periods of follow-up. The valve leaflets, however had normal excursion, were thin, opened with a triangular or oblong shape and had expected geometric valve area (1.7 and 1.6cm 2 respectively) measured by 3D trans-oesophageal echocardiographic planimetry. Pressure recovery upstream the valves accounted for 20% and 12% of total pressure gradients respectively. Dominant site for pressure drop was intra-valvular (75-85%). Such a phenomenon has not been reported in vivo for these two valve designs. Copyright © 2016. Published by Elsevier B.V.

  8. Designing an Electro-Hydraulic Control Module for an Open-Circuit Variable Displacement Pump

    DEFF Research Database (Denmark)

    Pedersen, Henrik Clemmensen; Andersen, Torben Ole; Hansen, Michael Rygaard

    2005-01-01

    , in the form of an electric control signal, under varying working conditions, when having access to engine speed and actual pump pressure. The paper presents a model of both the pump and the control module, along with design considerations on which linear controllers are developed for a worst point......This paper deals with the problem of designing an electric control module for a Sauer-Danfoss Series 45 H-frame open circuit axial piston pump. The purpose of the electric control module is to replace the existing hydro-mechanical (LS) regulator, and enable the pump to follow a reference pressure...

  9. Hyperglycemia acutely lowers the postprandial excursions of glucagon-like Peptide-1 and gastric inhibitory polypeptide in humans

    DEFF Research Database (Denmark)

    Vollmer, Kirsten; Gardiwal, Husai; Menge, Bjoern A

    2009-01-01

    INTRODUCTION: Impaired secretion of glucagon-like peptide 1 (GLP-1) has been suggested to contribute to the deficient incretin effect in patients with type 2 diabetes. It is unclear whether this is a primary defect or a consequence of the hyperglycemia in type 2 diabetes. We examined whether acute...... hyperglycemia reduces the postprandial excursions of gastric inhibitory polypeptide (GIP) and GLP-1, and if so, whether this can be attributed to changes in gastric emptying. PATIENTS AND METHODS: Fifteen nondiabetic individuals participated in a euglycemic clamp and a hyperglycemic clamp experiment, carried...... the hyperglycemic clamp experiments and 83 +/- 3 mg/dl during the euglycemia (P hyperglycemia, but meal ingestion led to a decline in glucose requirements in both experiments (P

  10. Origin of Infrared Light Modulation in Reflectance-Mode Photoplethysmography.

    Directory of Open Access Journals (Sweden)

    Igor S Sidorov

    Full Text Available We recently pointed out the important role of dermis deformation by pulsating arterial pressure in the formation of a photoplethysmographic signal at green light. The aim of this study was to explore the role of this novel finding in near-infrared (NIR light. A light-emitting diode (LED-based imaging photoplethysmography (IPPG system was used to detect spatial distribution of blood pulsations under frame-to-frame switching green and NIR illumination in the palms of 34 healthy individuals. We observed a significant increase of light-intensity modulation at the heartbeat frequency for both illuminating wavelengths after a palm was contacted with a glass plate. Strong positive correlation between data measured at green and NIR light was found, suggesting that the same signal was read independently from the depth of penetration. Analysis of the data shows that an essential part of remitted NIR light is modulated in time as a result of elastic deformations of dermis caused by variable blood pressure in the arteries. Our observations suggest that in contrast with the classical model, photoplethysmographic waveform originates from the modulation of the density of capillaries caused by the variable pressure applied to the skin from large blood vessels. Particularly, beat-to-beat transmural pressure in arteries compresses/decompresses the dermis and deforms its connective-tissue components, thus affecting the distance between the capillaries, which results in the modulation of absorption and scattering coefficients of both green and NIR light. These findings are important for the correct interpretation of this widely used medical technique, which may have novel applications in diagnosis and treatment monitoring of aging and skin diseases.

  11. Two-phase flow and thermal response from nuclear excursions in tuff

    International Nuclear Information System (INIS)

    Rath, J.S.; Sanchez, L.C.; Taylor, L.L.

    1998-05-01

    Thermal hydrology calculations were performed to predict the geologic thermal and saturation response of a far-field nuclear criticality. The thermal hydrology (THX) calculations used an experimental version of a transient multi-phase fluid and energy simulator, BRAGFLO T. A total of 45 THX calculations were completed using various combinations of initial saturation S 0 , input heat generation zone (HGZ) radii r 0 , input energies E 0 , and input space power density functions (SPDFs). The thermal hydrology calculations were performed as a part the nuclear dynamics consequence analysis (NDCA) study for potential criticality consequences associated with disposal of high-level waste (HLW) and spent nuclear fuel (SNF) in an underground geologic repository. In the NDCA study it was identified that total fission energy E 0 , integrated from the power-time history, has an expected range of 10 17 --10 20 total fissions per excursion. This range of values is comparable to those reported for aqueous criticality accidents that had occurred in processing plants. The THX results show (using the conservative temperature recycle times) that a criticality frequency between 3 and 30 criticalities/yr is possible. Probability frequencies (generated by probabilistic risk analysis and the THX model) for these consequences indicate that any additional fissions are minor contributions to the biological hazards caused by the disposed fissile materials

  12. Is autonomic modulation different between European and Chinese astronauts?

    Science.gov (United States)

    Liu, Jiexin; Li, Yongzhi; Verheyden, Bart; Chen, Shanguang; Chen, Zhanghuang; Gai, Yuqing; Liu, Jianzhong; Gao, Jianyi; Xie, Qiong; Yuan, Ming; Li, Qin; Li, Li; Aubert, André E

    2015-01-01

    The objective was to investigate autonomic control in groups of European and Chinese astronauts and to identify similarities and differences. Beat-to-beat heart rate and finger blood pressure, brachial blood pressure, and respiratory frequency were measured from 10 astronauts (five European taking part in three different space missions and five Chinese astronauts taking part in two different space missions). Data recording was performed in the supine and standing positions at least 10 days before launch, and 1, 3, and 10 days after return. Cross-correlation analysis of heart rate and systolic pressure was used to assess cardiac baroreflex modulation. A fixed breathing protocol was performed to measure respiratory sinus arrhythmia and low-frequency power of systolic blood pressure variability. Although baseline cardiovascular parameters before spaceflight were similar in all astronauts in the supine position, a significant increase in sympathetic activity and a decrease in vagal modulation occurred in the European astronauts when standing; spaceflight resulted in a remarkable vagal decrease in European astronauts only. Similar baseline supine and standing values for heart rate, mean arterial pressure, and respiratory frequency were shown in both groups. Standing autonomic control was based on a balance of higher vagal and sympathetic modulation in European astronauts. Post-spaceflight orthostatic tachycardia was observed in all European astronauts, whereas post-spaceflight orthostatic tachycardia was significantly reduced in Chinese astronauts. The basis for orthostatic intolerance is not apparent; however, many possibilities can be considered and need to be further investigated, such as genetic diversities between races, astronaut selection, training, and nutrition, etc.

  13. Is autonomic modulation different between European and Chinese astronauts?

    Directory of Open Access Journals (Sweden)

    Jiexin Liu

    Full Text Available The objective was to investigate autonomic control in groups of European and Chinese astronauts and to identify similarities and differences.Beat-to-beat heart rate and finger blood pressure, brachial blood pressure, and respiratory frequency were measured from 10 astronauts (five European taking part in three different space missions and five Chinese astronauts taking part in two different space missions. Data recording was performed in the supine and standing positions at least 10 days before launch, and 1, 3, and 10 days after return. Cross-correlation analysis of heart rate and systolic pressure was used to assess cardiac baroreflex modulation. A fixed breathing protocol was performed to measure respiratory sinus arrhythmia and low-frequency power of systolic blood pressure variability.Although baseline cardiovascular parameters before spaceflight were similar in all astronauts in the supine position, a significant increase in sympathetic activity and a decrease in vagal modulation occurred in the European astronauts when standing; spaceflight resulted in a remarkable vagal decrease in European astronauts only. Similar baseline supine and standing values for heart rate, mean arterial pressure, and respiratory frequency were shown in both groups. Standing autonomic control was based on a balance of higher vagal and sympathetic modulation in European astronauts.Post-spaceflight orthostatic tachycardia was observed in all European astronauts, whereas post-spaceflight orthostatic tachycardia was significantly reduced in Chinese astronauts. The basis for orthostatic intolerance is not apparent; however, many possibilities can be considered and need to be further investigated, such as genetic diversities between races, astronaut selection, training, and nutrition, etc.

  14. Modulation of blood pressure response to exercise by physical activity and relationship with resting blood pressure during pregnancy.

    Science.gov (United States)

    Bisson, Michèle; Rhéaume, Caroline; Bujold, Emmanuel; Tremblay, Angelo; Marc, Isabelle

    2014-07-01

    To determine whether physical activity and blood pressure (BP) response to exercise in early pregnancy are related to resting BP at the end of pregnancy. Understanding physiological BP responses to exercise during pregnancy will help in improving BP profile and guiding exercise recommendations in pregnant women. Maternal physical activity, cardiorespiratory fitness (VO2peak) and BP (systolic and diastolic) at rest and during exercise (submaximal and relative response) were assessed at 16 weeks of gestation in 61 normotensive pregnant women. BP at 36 weeks of gestation and obstetrical outcomes were collected from maternal charts. Related to resting DBP at 16 weeks (r =  -0.28, P = 0.028), total energy expenditure spend at any physical activity in early pregnancy was also associated with resting SBP at 36 weeks (r =  -0.27, P = 0.038). On the contrary, although related to VO2peak (r =  -0.57, P sports and exercise (r =  -0.29, P = 0.024), the relative SBP response to exercise at 16 weeks was not associated with resting BP at 36 weeks. Strongly associated with resting BP at 16 weeks and also with total energy expenditure, submaximal BP response to exercise at 16 weeks was related to resting SBP and DBP at 36 weeks (r = 0.41, P = 0.001 and r = 0.26, P = 0.051, respectively). In normotensive women, physical activity performed in early pregnancy appears to slightly modulate resting BP in early and late pregnancy. However, further investigations are needed to determine which physical activity-related parameter in response to exercise best predicts BP variations during pregnancy.

  15. A 20-15 ka high-resolution paleomagnetic secular variation record from Black Sea sediments - no evidence for the 'Hilina Pali excursion'?

    Science.gov (United States)

    Liu, Jiabo; Nowaczyk, Norbert R.; Frank, Ute; Arz, Helge W.

    2018-06-01

    A comprehensive magnetostratigraphic investigation on sixteen sediment cores from the southeastern Black Sea yielded a very detailed high-quality paleosecular variation (PSV) record spanning from 20 to 15 ka. The age models are based on radiocarbon dating, stratigraphic correlation, and tephrochronology. Further age constraints were obtained by correlating four meltwater events, described from the western Black Sea, ranging in age from about 17 to 15 ka, with maxima in K/Ti ratios, obtained from X-ray fluorescence (XRF) scanning, and minima in S-ratios, reflecting increased hematite content, in the studied cores. Since the sedimentation rates in the investigated time window are up to 50 cm ka-1, the obtained PSVs records enabled a stacking using 50-yr bins. A directional anomaly at 18.5 ka, associated with pronounced swings in inclination and declination, as well as a low in relative paleointensity (rPI), is probably contemporaneous with the Hilina Pali excursion, originally reported from Hawaiian lava flows. However, virtual geomagnetic poles (VGPs) calculated from Black Sea sediments are not located at latitudes lower than 60°N, which denotes normal, though pronounced secular variations. During the postulated Hilina Pali excursion, the VGPs calculated from Black Sea data migrated clockwise only along the coasts of the Arctic Ocean from NE Canada (20.0 ka), via Alaska (18.6 ka) and NE Siberia (18.0 ka) to Svalbard (17.0 ka), then looping clockwise through the Eastern Arctic Ocean.

  16. Ion transport membrane module and vessel system with directed internal gas flow

    Science.gov (United States)

    Holmes, Michael Jerome; Ohrn, Theodore R.; Chen, Christopher Ming-Poh

    2010-02-09

    An ion transport membrane system comprising (a) a pressure vessel having an interior, an inlet adapted to introduce gas into the interior of the vessel, an outlet adapted to withdraw gas from the interior of the vessel, and an axis; (b) a plurality of planar ion transport membrane modules disposed in the interior of the pressure vessel and arranged in series, each membrane module comprising mixed metal oxide ceramic material and having an interior region and an exterior region; and (c) one or more gas flow control partitions disposed in the interior of the pressure vessel and adapted to change a direction of gas flow within the vessel.

  17. Resonant transducers for solid-state plasma density modulation

    Energy Technology Data Exchange (ETDEWEB)

    Hallock, Gary A., E-mail: hallock@ece.utexas.edu [The University of Texas at Austin, Austin, Texas 78701 (United States); Meier, Mark A., E-mail: mark.a.meier@exxonmobil.com [ExxonMobil Upstream Research Company, Houston, Texas 77389 (United States)

    2016-04-15

    We have developed transducers capable of modulating the plasma density and plasma density gradients in indium antimonide. These transducers make use of piezoelectric drivers to excite acoustic pressure resonance at 3λ/2, generating large amplitude standing waves and plasma density modulations. The plasma density has been directly measured using a laser diagnostic. A layered media model shows good agreement with the experimental measurements.

  18. All-optical pressure sensor

    DEFF Research Database (Denmark)

    2014-01-01

    The present invention relates to an all-optical pressure sensor comprising a waveguide accommodating a distributed Bragg reflector. Pressure sensing can then be provided by utilizing effective index modulation of the waveguide and detection of a wavelength shift of light reflected from the Bragg...... reflector. Sound sensing may also be provided thereby having an all-optical microphone. One embodiment of the invention relates to an optical pressure sensor comprising at least one outer membrane and a waveguide, the waveguide comprising at least one core for confining and guiding light,at least one...... distributed Bragg reflector located in said at least one core, and at least one inner deflecting element forming at least a part of the core,wherein the pressure sensor is configured such that the geometry and/or dimension of the at least one core is changed when the at least one outer membrane is submitted...

  19. AUTOLOAD, an automatic optimal pressurized water reactor reload design system with an expert module

    International Nuclear Information System (INIS)

    Li, Z.; Levine, S.H.

    1994-01-01

    An automatic optimal pressurized water reactor (PWR) reload design expert system AUTOLOAD has been developed. It employs two important new techniques. The first is a new loading priority scheme that defines the optimal placement of the fuel in the core that has the maximum end-of-cycle state k eff . The second is a new power-shape-driven progressive iteration method for automatically determining the burnable poison (BP) loading in the fresh fuel assemblies. The Haling power distribution is used in converting the theoretically optimal solution into the practical design, which meets the design constraints for the given fuel assemblies. AUTOLOAD is a combination of C and FORTRAN languages. It requires only the required cycle length, the maximum peak normalized power, the BP type, the number of fresh fuel assemblies, the assembly burnup, and BP histories of the available fuel assemblies as its input. Knowledge-based modules have been built into the expert system computer code to perform all of the tasks involved in reloading a PWR. AUTOLOAD takes only ∼ 30 CPU min on an IBM 3090 600s mainframe to accomplish a practical reload design. A maximum of 12.5% fresh fuel enrichment saving is observed compared with the core used by the utility

  20. Nonlinear modulation of ionization waves

    International Nuclear Information System (INIS)

    Bekki, Naoaki

    1981-01-01

    In order to investigate the nonlinear characteristics of ionization waves (moving-striations) in the positive column of glow discharge, a nonlinear modulation of ionization waves in the region of the Pupp critical current is analysed by means of the reductive perturbation method. The modulation of ionization waves is described by a nonlinear Schroedinger type equation. The coefficients of the equation are evaluated using the data of the low pressure Argon-discharge, and the simple solutions (plane wave and envelope soliton type solutions) are presented. Under a certain condition an envelope soliton is propagated through the positive column. (author)

  1. Effect of flow leakage on the benchmarking of FLOWTRAN with Mark-22 mockup flow excursion test data from Babcock and Wilcox

    International Nuclear Information System (INIS)

    Chen, Kuo-Fu.

    1992-10-01

    This report presents a revised analysis of the Babcock and Wilcox (B and W) downflow flow excursion tests that accounts for leakage between flow channels in the test assembly. Leak rates were estimated by comparing results from the downflow tests with those for upflow tests conducted using an identical assembly with some minor modifications. The upflow test assembly did not contain leaks. This revised analyses shows that FLOWTRAN with the SRS working criterion conservatively predicts onset of flow instability without using a local peaking factor to model heat transfer variations near the ribs

  2. Fiber-linked interferometric pressure sensor

    Science.gov (United States)

    Beheim, G.; Fritsch, K.; Poorman, R. N.

    1987-01-01

    A fiber-optic pressure sensor is described which uses a diaphragm to modulate the mirror separation of a Fabry-Perot cavity (the sensing cavity). A multimode optical fiber delivers broadband light to the sensing cavity and returns the spectrally modulated light which the cavity reflects. The sensor's output spectrum is analyzed using a tunable Fabry-Perot cavity (the reference cavity) to determine the mismatch in the mirror separations of the two cavities. An electronic servo control uses this result to cause the mirror separation of the reference cavity to equal that of the sensing cavity. The displacement of the pressure-sensing diaphragm is then obtained by measuring the capacitance of the reference cavity's metal-coated mirrors. Relative to other fiber-optic sensors, an important advantage of this instrument is its high immunity to the effects of variations in both the transmissivity of the fiber link and the wavelength of the optical source.

  3. Multipathway modulation of exercise and glucose stress effects upon GH secretion in healthy men.

    Science.gov (United States)

    Veldhuis, Johannes D; Olson, Thomas P; Takahashi, Paul Y; Miles, John M; Joyner, Michael J; Yang, Rebecca J; Wigham, Jean

    2015-09-01

    Exercise evokes pulsatile GH release followed by autonegative feedback, whereas glucose suppresses GH release followed by rebound-like GH release (feedforward escape). Here we test the hypothesis that age, sex steroids, insulin, body composition and physical power jointly determine these dynamic GH responses. This was a prospectively randomized glucose-blinded study conducted in the Mayo Center for Advancing Translational Sciences in healthy men ages 19-77 years (N=23). Three conditions, fasting/rest/saline, fasting/exercise/saline and fasting/rest/iv glucose infusions, were used to drive GH dynamics during 10-min blood sampling for 6h. Linear correlation analysis was applied to relate peak/nadir GH dynamics to age, sex steroids, insulin, CT-estimated abdominal fat and physical power (work per unit time). Compared with the fasting/rest/saline (control) day, fasting/exercise/saline infusion evoked peak GH within 1h, followed by negative feedback 3-5h later. The dynamic GH excursion was strongly (R(2)=0.634) influenced by (i) insulin negatively (P=0.011), (ii) power positively (P=0.0008), and (iii) E2 positively (P=0.001). Dynamic glucose-modulated GH release was determined by insulin negatively (P=0.0039) and power positively (P=0.0034) (R(2)=0.454). Under rest/saline, power (P=0.031) and total abdominal fat (P=0.012) (R(2)=0.267) were the dominant correlates of GH excursions. In healthy men, dynamic GH perturbations induced by exercise and glucose are strongly related to physical power, insulin, estradiol, and body composition, thus suggesting a network of regulatory pathways. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Nuclear-fuel-cycle education: Module 5. In-core fuel management

    International Nuclear Information System (INIS)

    Levine, S.H.

    1980-07-01

    The purpose of this project was to develop a series of educational modules for use in nuclear-fuel-cycle education. These modules are designed for use in a traditional classroom setting by lectures or in a self-paced, personalized system of instruction. This module on in-core fuel management contains information on computational methods and theory; in-core fuel management using the Virginia Polytechnic Institute and State University computer modules; pressurized water reactor in-core fuel management; boiling water reactor in-core fuel management; and in-core fuel management for gas-cooled and fast reactors

  5. Laser power meter based on the Peltier effect

    International Nuclear Information System (INIS)

    Goldschmid, H.J.; Miller, L.A.; Paul, G.L.

    1984-01-01

    An isothermal power meter, in which the incoming radiation is balanced by thermoelectric cooling, has two substantial advantages: there are no heat losses to the surroundings, and a short response time should result from the smallness of the temperature excursions before balance is achieved. Experiments on prototype devices consisting of thermoelectric modules, made from bismuth telluride alloys, with nominally black-body receivers are reported. Laser powers in the range 100 to 550 mW were measured. In the most favoured arrangement, multijunction modules were used both to provide cooling through the Peltier effect and to detect any temperature excursions through the Seebeck effect. The results justify further work on the system

  6. Working gas temperature and pressure changes for microscale thermal creep-driven flow caused by discontinuous wall temperatures

    International Nuclear Information System (INIS)

    Han, Yen-Lin

    2010-01-01

    Microscale temperature gradient-driven (thermal creep/transpiration) gas flows have attracted significant interest during the past decade. For free molecular and transitional conditions, applying temperature gradients to a flow channel's walls induces the thermal creep effect. This results in a working gas flowing through the channel from cold to hot, which is generally accompanied by a rising pressure from cold to hot in the channel. Working gas temperature and pressure distributions can vary significantly, depending on a flow channel's configuration and wall temperature distribution. Understanding working gas temperature excursions, both increases and decreases, is essential to ensure the effective use of thermal creep flows in microscale applications. In this study, the characterizations of working gas temperature variations, due to both temperature discontinuities and more gradual changes, on a variety of flow channel walls, were systematically investigated using the direct simulation Monte Carlo (DSMC) method. A micro/meso-scale pump, the Knudsen compressor, was chosen to illustrate the importance of controlling working gas temperature in thermal creep-driven flows. Gas pressure and temperature variations, through several Knudsen compressor stage configurations, were studied to determine the most advantageous flow phenomena for the efficient operation of Knudsen compressors.

  7. Operating characteristics of a 0.87 kW-hr flywheel energy storage module

    Science.gov (United States)

    Loewenthal, S. H.; Scibbe, H. W.; Parker, R. D.; Zaretsky, E. V.

    1985-01-01

    Discussion is given of the design and loss characteristics of 0.87 kW-hr (peak) flywheel energy storage module suitable for aerospace and automotive applications. The maraging steel flywheel rotor, a 46-cm- (18-in-) diameter, 58-kg (128-lb) tapered disk, delivers 0.65 kW-hr of usable energy between operating speeds of 10,000 and 20,000 rpm. The rotor is supported by 20- and 25-mm bore diameter, deep-groove ball bearings, lubricated by a self-replenishing wick type lubrication system. To reduce aerodynamic losses, the rotor housing was evacuated to vacuum levels from 40 to 200 millitorr. Dynamic rotor instabilities uncovered during testing necessitated the use of an elastometric-bearing damper to limit shaft excursions. Spindown losses from bearing, seal, and aerodynamic drag at 50 millitorr typically ranged from 64 to 193 W at 10,000 and 20,000 rpm, respectively. Discharge efficiency of the flywheel system exceeded 96 percent at torque levels greater than 21 percent of rated torque.

  8. Gender Differences in Behavioral and Neural Responses to Unfairness Under Social Pressure.

    Science.gov (United States)

    Zheng, Li; Ning, Reipeng; Li, Lin; Wei, Chunli; Cheng, Xuemei; Zhou, Chu; Guo, Xiuyan

    2017-10-18

    Numerous studies have revealed the key role of social pressure on individuals' decision-making processes. However, the impact of social pressure on unfairness-related decision-making processes remains unclear. In the present study, we investigated how social pressure modulated men's and women's responses in an ultimatum game. Twenty women and eighteen men played the ultimatum game as responders in the scanner, where fair and unfair offers were tendered by proposers acting alone (low pressure) or by proposers endorsed by three supporters (high pressure). Results showed that men rejected more, whereas women accepted more unfair offers in the high versus low pressure context. Neurally, pregenual anterior cingulate cortex activation in women positively predicted their acceptance rate difference between contexts. In men, stronger right anterior insula activation and increased connectivity between right anterior insula and dorsal anterior cingulate cortex were observed when they receiving unfair offers in the high than low pressure context. Furthermore, more bilateral anterior insula and left dorsolateral prefrontal cortex activations were found when men rejected (relative to accepted) unfair offers in the high than low pressure context. These findings highlighted gender differences in the modulation of behavioral and neural responses to unfairness by social pressure.

  9. Paraventricular Nucleus Modulates Excitatory Cardiovascular Reflexes during Electroacupuncture

    Science.gov (United States)

    Tjen-A-Looi, Stephanie C.; Guo, Zhi-Ling; Fu, Liang-Wu; Longhurst, John C.

    2016-01-01

    The paraventricular nucleus (PVN) regulates sympathetic outflow and blood pressure. Somatic afferent stimulation activates neurons in the hypothalamic PVN. Parvocellular PVN neurons project to sympathoexcitatory cardiovascular regions of the rostral ventrolateral medulla (rVLM). Electroacupuncture (EA) stimulates the median nerve (P5-P6) to modulate sympathoexcitatory responses. We hypothesized that the PVN and its projections to the rVLM participate in the EA-modulation of sympathoexcitatory cardiovascular responses. Cats were anesthetized and ventilated. Heart rate and mean blood pressure were monitored. Application of bradykinin every 10-min on the gallbladder induced consistent pressor reflex responses. Thirty-min of bilateral EA stimulation at acupoints P5-P6 reduced the pressor responses for at least 60-min. Inhibition of the PVN with naloxone reversed the EA-inhibition. Responses of cardiovascular barosensitive rVLM neurons evoked by splanchnic nerve stimulation were reduced by EA and then restored with opioid receptor blockade in the PVN. EA at P5-P6 decreased splanchnic evoked activity of cardiovascular barosensitive PVN neurons that also project directly to the rVLM. PVN neurons labeled with retrograde tracer from rVLM were co-labeled with μ-opioid receptors and juxtaposed to endorphinergic fibers. Thus, the PVN and its projection to rVLM are important in processing acupuncture modulation of elevated blood pressure responses through a PVN opioid mechanism. PMID:27181844

  10. Attention-related modulation of auditory brainstem responses during contralateral noise exposure.

    Science.gov (United States)

    Ikeda, Kazunari; Sekiguchi, Takahiro; Hayashi, Akiko

    2008-10-29

    As determinants facilitating attention-related modulation of the auditory brainstem response (ABR), two experimental factors were examined: (i) auditory discrimination; and (ii) contralateral masking intensity. Tone pips at 80 dB sound pressure level were presented to the left ear via either single-tone exposures or oddball exposures, whereas white noise was delivered continuously to the right ear at variable intensities (none--80 dB sound pressure level). Participants each conducted two tasks during stimulation, either reading a book (ignoring task) or detecting target tones (attentive task). Task-related modulation within the ABR range was found only during oddball exposures at contralateral masking intensities greater than or equal to 60 dB. Attention-related modulation of ABR can thus be detected reliably during auditory discrimination under contralateral masking of sufficient intensity.

  11. Concentrated pitch discrimination modulates auditory brainstem responses during contralateral noise exposure.

    Science.gov (United States)

    Ikeda, Kazunari; Sekiguchi, Takahiro; Hayashi, Akiko

    2010-03-31

    This study examined a notion that auditory discrimination is a requisite for attention-related modulation of the auditory brainstem response (ABR) during contralateral noise exposure. Given that the right ear was exposed continuously with white noise at an intensity of 60-80 dB sound pressure level, tone pips at 80 dB sound pressure level were delivered to the left ear through either single-stimulus or oddball procedures. Participants conducted reading (ignoring task) and counting target tones (attentive task) during stimulation. The oddball but not the single-stimulus procedures elicited task-related modulations in both early (ABR) and late (processing negativity) event-related potentials simultaneously. The elicitation of the attention-related ABR modulation during contralateral noise exposure is thus considered to require auditory discrimination and have the corticofugal nature evidently.

  12. Towards an Excursion Flora for Austria and all the Eastern Alps

    Directory of Open Access Journals (Sweden)

    Manfred A. Fischer

    2018-02-01

    Full Text Available This is on the one hand an announcement of the two-volume Fourth Edition of the Excursion Flora for Austria expanded by also including the remaining parts of the Eastern Alps (chapter 1, and on the other hand a rough survey of the flora of the Eastern Alps in connection with the main vegetation types (chapter 2. The geographical scope includes, besides Austria, the entire Eastern Alps from the Rhine valley in E Switzerland (Grisons to the Vipava valley in SW Slovenia. Volume 1 mainly contains comprehensive introductory chapters like introductions to plant morphology, taxonomy, and nomenclature, as well as a sketch of ecomorphology and habitat ecology, a survey of vegetation types (phytosociology and floristic peculiarities of the different natural regions, a rough history of floristic research, a detailed glossary including the meaning of epithets, etc., and drawings of several plant species characteristic of the flora covered. The structure of the keys concentrated in volume 2 is explained: besides the descriptive traits, they include for each taxon comprehensive ecological and plant geographical data, as well as information about Red Lists of the countries involved, plant uses, and taxonomical problems. Genus names are given not only in German, but also in the Romansh (Rumantsch Grischun, Italian, and Slovenian languages. In chapter 2, some important chorotypes including endemics are characterised, and an overview of floristic diversity (lists of exemplary taxa in accordance with the main and most characteristic vegetation types is presented.

  13. Impact of malnutrition on cardiac autonomic modulation in children

    Directory of Open Access Journals (Sweden)

    Gláucia Siqueira Carvalho Barreto

    2016-11-01

    Conclusion: Malnourished children present changes in cardiac autonomic modulation, characterized by reductions in both sympathetic and parasympathetic activity, as well as increased heart rate and decreased blood pressure.

  14. Longitudinal On-Column Thermal Modulation for Comprehensive Two-Dimensional Liquid Chromatography.

    Science.gov (United States)

    Creese, Mari E; Creese, Mathew J; Foley, Joe P; Cortes, Hernan J; Hilder, Emily F; Shellie, Robert A; Breadmore, Michael C

    2017-01-17

    Longitudinal on-column thermal modulation for comprehensive two-dimensional liquid chromatography is introduced. Modulation optimization involved a systematic investigation of heat transfer, analyte retention, and migration velocity at a range of temperatures. Longitudinal on-column thermal modulation was realized using a set of alkylphenones and compared to a conventional valve-modulator employing sample loops. The thermal modulator showed a reduced modulation-induced pressure impact than valve modulation, resulting in reduced baseline perturbation by a factor of 6; yielding a 6-14-fold improvement in signal-to-noise. A red wine sample was analyzed to demonstrate the potential of the longitudinal on-column thermal modulator for separation of a complex sample. Discrete peaks in the second dimension using the thermal modulator were 30-55% narrower than with the valve modulator. The results shown herein demonstrate the benefits of an active focusing modulator, such as reduced detection limits and increased total peak capacity.

  15. Feasibility of kilovoltage x-ray energy modulation by gaseous media and its application in contrast-enhanced radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Facundo-Flores, E. L.; Garnica-Garza, H. M. [Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Unidad Monterrey, Vía del Conocimiento 201 Parque PIIT, Apodaca, Nuevo León 66600 (Mexico)

    2013-09-15

    Purpose: To present a method to modulate the energy contents of a kilovoltage x-ray beam that makes use of a gas as the modulating medium. The method is capable of producing arbitrary x-ray spectra by varying the pressure of the modulating gas and the peak kilovoltage (kVp) of the x-ray beams whose energy is being modulated.Methods: An aluminum chamber was machined with a 0.5 cm wall thickness, designed to withstand pressures of more than 80 atm. A pressure sensor and electrovalves were used to monitor and regulate the gas pressure. Argon was used as the modulating gas. A CdTe spectrometer was used to measure x-ray spectra for different combinations of kVp and gas pressure, thus obtaining a set of basis x-ray functions. An arbitrary x-ray spectrum can then be formed by the linear combination of such basis functions. In order to show one possible application of the modulation method, a contrast-enhanced radiotherapy prostate treatment was optimized with respect to the x-ray beam energy, without restrictions on the possible shape of the resultant x-ray spectra.Results: The x-ray spectra basis functions obtained display a smooth and gradual variation of their average energy as a function of the gas pressure for a given kVp, sometimes in the order of 1 or 2 keV. This gradual variation would be difficult to obtain with a conventional aluminum or copper filters, as the change in thickness necessary to reproduce the data presented would be in the order of micrometers, making necessary the use of a large number of such filters. Using the modulation method presented here, the authors were able to reconstruct the optimized x-ray spectra from the measured basis functions, for different optimization objectives.Conclusions: A method has been developed that allows for the controlled modulation of the energy contents of kilovoltage x-ray spectra. The method has been shown to be able to reproduce spectra of arbitrary shape, such as those obtained from the optimization of contrast

  16. Thermodynamic analysis of energy density in pressure retarded osmosis: The impact of solution volumes and costs

    International Nuclear Information System (INIS)

    Reimund, Kevin K.

    2015-01-01

    A general method was developed for estimating the volumetric energy efficiency of pressure retarded osmosis via pressure-volume analysis of a membrane process. The resulting model requires only the osmotic pressure, π, and mass fraction, w, of water in the concentrated and dilute feed solutions to estimate the maximum achievable specific energy density, uu, as a function of operating pressure. The model is independent of any membrane or module properties. This method utilizes equilibrium analysis to specify the volumetric mixing fraction of concentrated and dilute solution as a function of operating pressure, and provides results for the total volumetric energy density of similar order to more complex models for the mixing of seawater and riverwater. Within the framework of this analysis, the total volumetric energy density is maximized, for an idealized case, when the operating pressure is π(1+√w -1 ), which is lower than the maximum power density operating pressure, Δπ/2, derived elsewhere, and is a function of the solute osmotic pressure at a given mass fraction. It was also found that a minimum 1.45 kmol of ideal solute is required to produce 1 kWh of energy while a system operating at "maximum power density operating pressure" requires at least 2.9 kmol. Utilizing this methodology, it is possible to examine the effects of volumetric solution cost, operation of a module at various pressure, and operation of a constant pressure module with various feed.

  17. Acoustic field modulation in regenerators

    Science.gov (United States)

    Hu, J. Y.; Wang, W.; Luo, E. C.; Chen, Y. Y.

    2016-12-01

    The regenerator is a key component that transfers energy between heat and work. The conversion efficiency is significantly influenced by the acoustic field in the regenerator. Much effort has been spent to quantitatively determine this influence, but few comprehensive experimental verifications have been performed because of difficulties in modulating and measuring the acoustic field. In this paper, a method requiring two compressors is introduced and theoretically investigated that achieves acoustic field modulation in the regenerator. One compressor outputs the acoustic power for the regenerator; the other acts as a phase shifter. A RC load dissipates the acoustic power out of both the regenerator and the latter compressor. The acoustic field can be modulated by adjusting the current in the two compressors and opening the RC load. The acoustic field is measured with pressure sensors instead of flow-field imaging equipment, thereby greatly simplifying the experiment.

  18. Unity connecting module in SSPF

    Science.gov (United States)

    1998-01-01

    In the Space Station Processing Facility, the Unity connecting module, part of the International Space Station, is shown with Pressurized Mating Adapters 1 (left) and 2 (right) attached. Unity is scheduled to undergo testing of the common berthing mechanism to which other space station elements will dock. Unity is the primary payload on mission STS-88, targeted to launch Dec. 3, 1998. Other testing includes the Pad Demonstration Test to verify the compatibility of the module with the Space Shuttle as well as the ability of the astronauts to send and receive commands to Unity from the flight deck of the orbiter. Unity is expected to be ready for installation into the payload canister on Oct. 25, and transported to Launch Pad 39-A on Oct. 27. The Unity will be mated to the Russian-built Zarya control module which should already be in orbit at that time.

  19. Effect of Elevated Intracranial Pressure on Amplitudes and Frequency Tuning of Ocular Vestibular Evoked Myogenic Potentials Elicited by Bone-Conducted Vibration.

    Science.gov (United States)

    Gürkov, Robert; Speierer, Guillaume; Wittwer, Luis; Kalla, Roger

    Recently, it could be demonstrated that an increased intracranial pressure causes a modulation of the air conducted sound evoked ocular vestibular evoked myogenic potential (oVEMP). The mechanism for this modulation is not resolved and may depend on a change of either receptor excitability or sound energy transmission. oVEMPs were elicited in 18 healthy subjects with a minishaker delivering 500 and 1000 Hz tone bursts, in supine and tilted positions. The study could confirm the frequency tuning of oVEMP. However, at neither stimulus frequency could a modulating effect of increased intracranial pressure be observed. These data suggest that the observed modulation of the oVEMP response by an increased intracranial pressure is primarily due to the effect of an increased intralabyrinthine pressure onto the stiffness of the inner ear contents and the middle ear-inner ear junction. Future studies on the effect of intracranial pressure on oVEMP should use air-conducted sound and not bone-conducted vibration.

  20. A mechanism for frequency modulation in songbirds shared with humans.

    Science.gov (United States)

    Amador, Ana; Margoliash, Daniel

    2013-07-03

    In most animals that vocalize, control of fundamental frequency is a key element for effective communication. In humans, subglottal pressure controls vocal intensity but also influences fundamental frequency during phonation. Given the underlying similarities in the biomechanical mechanisms of vocalization in humans and songbirds, songbirds offer an attractive opportunity to study frequency modulation by pressure. Here, we present a novel technique for dynamic control of subsyringeal pressure in zebra finches. By regulating the opening of a custom-built fast valve connected to the air sac system, we achieved partial or total silencing of specific syllables, and could modify syllabic acoustics through more complex manipulations of air sac pressure. We also observed that more nuanced pressure variations over a limited interval during production of a syllable concomitantly affected the frequency of that syllable segment. These results can be explained in terms of a mathematical model for phonation that incorporates a nonlinear description for the vocal source capable of generating the observed frequency modulations induced by pressure variations. We conclude that the observed interaction between pressure and frequency was a feature of the source, not a result of feedback control. Our results indicate that, beyond regulating phonation or its absence, regulation of pressure is important for control of fundamental frequencies of vocalizations. Thus, although there are separate brainstem pathways for syringeal and respiratory control of song production, both can affect airflow and frequency. We hypothesize that the control of pressure and frequency is combined holistically at higher levels of the vocalization pathways.

  1. Frequency modulation spectroscopy with a THz quantum-cascade laser.

    Science.gov (United States)

    Eichholz, R; Richter, H; Wienold, M; Schrottke, L; Hey, R; Grahn, H T; Hübers, H-W

    2013-12-30

    We report on a terahertz spectrometer for high-resolution molecular spectroscopy based on a quantum-cascade laser. High-frequency modulation (up to 50 MHz) of the laser driving current produces a simultaneous modulation of the frequency and amplitude of the laser output. The modulation generates sidebands, which are symmetrically positioned with respect to the laser carrier frequency. The molecular transition is probed by scanning the sidebands across it. In this way, the absorption and the dispersion caused by the molecular transition are measured. The signals are modeled by taking into account the simultaneous modulation of the frequency and amplitude of the laser emission. This allows for the determination of the strength of the frequency as well as amplitude modulation of the laser and of molecular parameters such as pressure broadening.

  2. Cavity Preparation/assembly Techniques and Impact on Q, Realistic Q - Factors in a Module, Review of Modules

    Energy Technology Data Exchange (ETDEWEB)

    Peter Kneisel

    2005-03-19

    This contribution summarizes the surface preparation procedures for niobium cavities presently used both in laboratory experiments and for modules, such as buffered chemical polishing (BCP), electropolishing (EP), high pressure ultrapure water rinsing (HPR), CO{sub 2} snow cleaning and high temperature heat treatments for hydrogen degassing or postpurification. The impact of surface treatments and the degree of cleanliness during assembly procedures on cavity performance (Q - value and accelerating gradient E{sub acc}) will be discussed. In addition, an attempt will be made to summarize the experiences made in module assemblies in different labs/projects such as DESY(TTF), Jlab (Upgrade) and SNS.

  3. Thermodynamic analysis of energy density in pressure retarded osmosis: The impact of solution volumes and costs

    Energy Technology Data Exchange (ETDEWEB)

    Reimund, Kevin K. [Univ. of Connecticut, Storrs, CT (United States). Dept. of Chemical and Biomolecular Engineering; McCutcheon, Jeffrey R. [Univ. of Connecticut, Storrs, CT (United States). Dept. of Chemical and Biomolecular Engineering; Wilson, Aaron D. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-08-01

    A general method was developed for estimating the volumetric energy efficiency of pressure retarded osmosis via pressure-volume analysis of a membrane process. The resulting model requires only the osmotic pressure, π, and mass fraction, w, of water in the concentrated and dilute feed solutions to estimate the maximum achievable specific energy density, uu, as a function of operating pressure. The model is independent of any membrane or module properties. This method utilizes equilibrium analysis to specify the volumetric mixing fraction of concentrated and dilute solution as a function of operating pressure, and provides results for the total volumetric energy density of similar order to more complex models for the mixing of seawater and riverwater. Within the framework of this analysis, the total volumetric energy density is maximized, for an idealized case, when the operating pressure is π/(1+√w⁻¹), which is lower than the maximum power density operating pressure, Δπ/2, derived elsewhere, and is a function of the solute osmotic pressure at a given mass fraction. It was also found that a minimum 1.45 kmol of ideal solute is required to produce 1 kWh of energy while a system operating at “maximum power density operating pressure” requires at least 2.9 kmol. Utilizing this methodology, it is possible to examine the effects of volumetric solution cost, operation of a module at various pressure, and operation of a constant pressure module with various feed.

  4. High hydrostatic pressure induces pro-osteoarthritic changes in cartilage precursor cells: A transcriptome analysis.

    Science.gov (United States)

    Montagne, Kevin; Onuma, Yasuko; Ito, Yuzuru; Aiki, Yasuhiko; Furukawa, Katsuko S; Ushida, Takashi

    2017-01-01

    Due to the high water content of cartilage, hydrostatic pressure is likely one of the main physical stimuli sensed by chondrocytes. Whereas, in the physiological range (0 to around 10 MPa), hydrostatic pressure exerts mostly pro-chondrogenic effects in chondrocyte models, excessive pressures have been reported to induce detrimental effects on cartilage, such as increased apoptosis and inflammation, and decreased cartilage marker expression. Though some genes modulated by high pressure have been identified, the effects of high pressure on the global gene expression pattern have still not been investigated. In this study, using microarray technology and real-time PCR validation, we analyzed the transcriptome of ATDC5 chondrocyte progenitors submitted to a continuous pressure of 25 MPa for up to 24 h. Several hundreds of genes were found to be modulated by pressure, including some not previously known to be mechano-sensitive. High pressure markedly increased the expression of stress-related genes, apoptosis-related genes and decreased that of cartilage matrix genes. Furthermore, a large set of genes involved in the progression of osteoarthritis were also induced by high pressure, suggesting that hydrostatic pressure could partly mimic in vitro some of the genetic alterations occurring in osteoarthritis.

  5. Multi-unit shutdown due to boiler feedwater chemical excursion

    International Nuclear Information System (INIS)

    Diebel, M.E.

    1991-01-01

    Ontario Hydro's Bruce Nuclear Generating Station 'B' consists of four 935 W CANDU units located on the east shore of Lake Huron in the province of Ontario, Canada. On July 25 and 26, 1989 three of the four operating units were shutdown due to boiler feedwater chemical excursions initiated by a process upset in the Water Treatment Plant that provides demineralized make-up water to all four units. The chemicals that escaped from an ion exchange vessel during a routine regeneration very quickly spread through the condensate make-up system and into the boiler feedwater systems. This resulted in boiler sulfate levels exceeding shutdown limits. A total of 260 GWH of electrical generation was unexpectedly made unavailable to the grid at a time of peak seasonal demand. This event exposed several unforeseen deficiencies and vulnerabilities in the automatic demineralized water make-up quality protection scheme, system designs, operating procedures and the ability of operating personnel to recognize and appropriately respond to such an event. The combination of these factors contributed towards turning a minor system upset into a major multi-unit shutdown. This paper provides the details of the actual event initiation in the Water Treatment Plant and describes the sequence of events that led to the eventual shutdown of three units and near shutdown of the fourth. The design inadequacies, procedural deficiencies and operating personnel responses and difficulties are described. The process of recovering from this event, the flushing out of system piping, boilers and the feedwater train is covered as well as our experiences with setting up supplemental demineralized water supplies including trucking in water and the use of rental trailer mounted demineralizing systems. System design, procedural and operational changes that have been made and that are still being worked on in response to this event are described. The latest evidence of the effect of this event on boiler tube

  6. Generating pulsatility by pump speed modulation with continuous-flow total artificial heart in awake calves.

    Science.gov (United States)

    Fukamachi, Kiyotaka; Karimov, Jamshid H; Sunagawa, Gengo; Horvath, David J; Byram, Nicole; Kuban, Barry D; Dessoffy, Raymond; Sale, Shiva; Golding, Leonard A R; Moazami, Nader

    2017-12-01

    The purpose of this study was to evaluate the effects of sinusoidal pump speed modulation of the Cleveland Clinic continuous-flow total artificial heart (CFTAH) on hemodynamics and pump flow in an awake chronic calf model. The sinusoidal pump speed modulations, performed on the day of elective sacrifice, were set at ±15 and ± 25% of mean pump speed at 80 bpm in four awake calves with a CFTAH. The systemic and pulmonary arterial pulse pressures increased to 12.0 and 12.3 mmHg (±15% modulation) and to 15.9 and 15.7 mmHg (±25% modulation), respectively. The pulsatility index and surplus hemodynamic energy significantly increased, respectively, to 1.05 and 1346 ergs/cm at ±15% speed modulation and to 1.51 and 3381 ergs/cm at ±25% speed modulation. This study showed that it is feasible to generate pressure pulsatility with pump speed modulation; the platform is suitable for evaluating the physiologic impact of pulsatility and allows determination of the best speed modulations in terms of magnitude, frequency, and profiles.

  7. Higher order magnetic modulation structures in rare earth metal, alloys and compounds under extreme conditions

    International Nuclear Information System (INIS)

    Kawano, S.

    2003-01-01

    Magnetic materials consisting of rare earth ions form modulation structures such as a helical or sinusoidal structure caused by the oscillating magnetic interaction between rare earth ions due to RKKY magnetic interaction. These modulation structures, in some cases, develop further to higher order modulation structures by additional modulations caused by higher order crystalline electric field, magnetic interactions such as spin-lattice interaction, external magnetic field and pressure. The higher order modulation structures are observed in a spin-slip structure or a helifan structure in Ho, and a tilt helix structure in a TbEr alloy. Paramagnetic ions originated from frustration generate many magnetic phases under applied external magnetic field. KUR neutron diffraction groups have performed the development and adjustment of high-pressure instruments and external magnetic fields for neutron diffraction spectrometers. The studies of 'neutron diffraction under extreme conditions' by the seven groups are described in this report. (Y. Kazumata)

  8. Promotion of Cultural Content Knowledge through the Use of the History and Philosophy of Science

    Science.gov (United States)

    Galili, Igal

    2012-01-01

    Historical excurse was suggested as a beneficial form of using the history and philosophy of science in the modules of learning materials developed within the History and Philosophy in Science Teaching project. The paper briefly describes the theoretical framework of the produced modules, addressing ontological and epistemological aspects of…

  9. Meal sequence and glucose excursion, gastric emptying and incretin secretion in type 2 diabetes: a randomised, controlled crossover, exploratory trial.

    Science.gov (United States)

    Kuwata, Hitoshi; Iwasaki, Masahiro; Shimizu, Shinobu; Minami, Kohtaro; Maeda, Haruyo; Seino, Susumu; Nakada, Koji; Nosaka, Chihiro; Murotani, Kenta; Kurose, Takeshi; Seino, Yutaka; Yabe, Daisuke

    2016-03-01

    Investigation of dietary therapy for diabetes has focused on meal size and composition; examination of the effects of meal sequence on postprandial glucose management is limited. The effects of fish or meat before rice on postprandial glucose excursion, gastric emptying and incretin secretions were investigated. The experiment was a single centre, randomised controlled crossover, exploratory trial conducted in an outpatient ward of a private hospital in Osaka, Japan. Patients with type 2 diabetes (n = 12) and healthy volunteers (n = 10), with age 30-75 years, HbA1c 9.0% (75 mmol/mol) or less, and BMI 35 kg/m(2) or less, were randomised evenly to two groups by use of stratified randomisation, and subjected to meal sequence tests on three separate mornings; days 1 and 2, rice before fish (RF) or fish before rice (FR) in a crossover fashion; and day 3, meat before rice (MR). Pre- and postprandial levels of glucose, insulin, C-peptide and glucagon as well as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide were evaluated. Gastric emptying rate was determined by (13)C-acetate breath test involving measurement of (13)CO2 in breath samples collected before and after ingestion of rice steamed with (13)C-labelled sodium acetate. Participants, people doing measurements or examinations, and people assessing the outcomes were not blinded to group assignment. FR and MR in comparison with RF ameliorated postprandial glucose excursion (AUC-15-240 min-glucose: type 2 diabetes, FR 2,326.6 ± 114.7 mmol/l × min, MR 2,257.0 ± 82.3 mmol/l × min, RF 2,475.6 ± 87.2 mmol/l × min [p Japan Society for Promotion of Science, Japan Association for Diabetes Education and Care, and Japan Vascular Disease Research Foundation.

  10. Hip strength and star excursion balance test deficits of patients with chronic ankle instability.

    Science.gov (United States)

    McCann, Ryan S; Crossett, Ian D; Terada, Masafumi; Kosik, Kyle B; Bolding, Brenn A; Gribble, Phillip A

    2017-11-01

    To examine isometric hip strength in those with and without CAI, and determine the degree of Star Excursion Balance Test (SEBT) variance explained by isometric hip strength. Single-blinded, cross-sectional, case-control study. Thirty individuals with CAI, 29 lateral ankle sprain (LAS) copers, and 26 healthy controls participated. We assessed dynamic postural control with the SEBT anterior (SEBT-ANT), posteromedial (SEBT-PM), and posterolateral (SEBT-PL) reaches, and isometric hip extension (EXT), abduction (ABD) and external rotation (ER) strength with hand-held dynamometry. The CAI and LAS coper groups' involved limbs and randomly selected limbs in controls were tested. Separate Kruskal-Wallis tests compared SEBT scores and isometric hip strength between groups. Backwards linear regression models determined the degree of SEBT variance explained by isometric hip strength. Statistical significance was set a priori at Phip strength compared to LAS copers and controls. Additionally, the CAI group's isometric hip strength significantly influenced dynamic postural control performance. Future CAI rehabilitation strategies should consider hip muscular strengthening to facilitate improvements in dynamic postural control. Copyright © 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  11. Lung heparan sulfates modulate Kfc during increased vascular pressure: evidence for glycocalyx-mediated mechanotransduction

    Science.gov (United States)

    Cluff, Mark; Kingston, Joseph; Hill, Denzil; Chen, Haiyan; Hoehne, Soeren; Malleske, Daniel T.; Kaur, Rajwinederjit

    2012-01-01

    Lung endothelial cells respond to changes in vascular pressure through mechanotransduction pathways that alter barrier function via non-Starling mechanism(s). Components of the endothelial glycocalyx have been shown to participate in mechanotransduction in vitro and in systemic vessels, but the glycocalyx's role in mechanosensing and pulmonary barrier function has not been characterized. Mechanotransduction pathways may represent novel targets for therapeutic intervention during states of elevated pulmonary pressure such as acute heart failure, fluid overload, and mechanical ventilation. Our objective was to assess the effects of increasing vascular pressure on whole lung filtration coefficient (Kfc) and characterize the role of endothelial heparan sulfates in mediating mechanotransduction and associated increases in Kfc. Isolated perfused rat lung preparation was used to measure Kfc in response to changes in vascular pressure in combination with superimposed changes in airway pressure. The roles of heparan sulfates, nitric oxide, and reactive oxygen species were investigated. Increases in capillary pressure altered Kfc in a nonlinear relationship, suggesting non-Starling mechanism(s). nitro-l-arginine methyl ester and heparanase III attenuated the effects of increased capillary pressure on Kfc, demonstrating active mechanotransduction leading to barrier dysfunction. The nitric oxide (NO) donor S-nitrosoglutathione exacerbated pressure-mediated increase in Kfc. Ventilation strategies altered lung NO concentration and the Kfc response to increases in vascular pressure. This is the first study to demonstrate a role for the glycocalyx in whole lung mechanotransduction and has important implications in understanding the regulation of vascular permeability in the context of vascular pressure, fluid status, and ventilation strategies. PMID:22160307

  12. Investigation on the effect of temperature excursion on the helium defects of tungsten surface by using compact plasma device

    International Nuclear Information System (INIS)

    Takamura, S.; Miyamoto, T.; Tomida, Y.; Minagawa, T.; Ohno, N.

    2011-01-01

    The effects of temperature excursion on the helium defects of tungsten surface have been investigated by using compact plasma device AIT-PID (Aichi Institute of Technology - Plasma Irradiation Device). An initial stage of bubble formation has been identified with an order of smaller (sub-micron) bubbles and holes than those in the past in which the micron size is the standard magnitude. The radiation cooling has been detected when a blacking of tungsten surface coming from nanostructure formation is proceeding due to an increase in the emissivity. The temperature increase to the domain (∼1600 K) in bubble/hole formation from that in nanostructure formation has been found to bring a constriction in diameter and a reduction in length of fiber-form nanostructure.

  13. Engineering and licensing progress of the HTR-Module

    Energy Technology Data Exchange (ETDEWEB)

    Weisbrodt, I A

    1988-07-01

    This report deals not only with the latest status of Siemens/Interatom's HTR-Module but also reflects the latest engineering and licensing progress of the HTR-Module against the background of the specified design requirements and of the discussions on passively safe reactors. Therefore, I intend to report also about two examples of the accident analysis - one design basis accident, i.e. the leak-before-break of the reactor pressure vessel and one beyond design accident, i. e. massive water ingress.

  14. Engineering and licensing progress of the HTR-Module

    International Nuclear Information System (INIS)

    Weisbrodt, I.A.

    1988-01-01

    This report deals not only with the latest status of Siemens/Interatom's HTR-Module but also reflects the latest engineering and licensing progress of the HTR-Module against the background of the specified design requirements and of the discussions on passively safe reactors. Therefore, I intend to report also about two examples of the accident analysis - one design basis accident, i.e. the leak-before-break of the reactor pressure vessel and one beyond design accident, i. e. massive water ingress

  15. Pressure effects on distribution of solids in a PFBC-plant

    Energy Technology Data Exchange (ETDEWEB)

    Pavlovec, V.; Linzer, W. [Technische Univ., Vienna (Austria)

    1999-07-01

    With Pressurized Fluidized Beds some peculiarities have to be regarded when comparing them to atmospheric systems with the same power output. There is a significant influence on solids distribution of the growing density at increasing pressure, not only by means of density itself, but also due to changes in drag coefficients and - at pressures above approx. 16 bar - due to the pressure effect on gas properties. In addition to these effects on homogeneous fluidization there is an influence on formation and behavior of bubbles in dense beds. During the redesign of a simulation program (that had been originally designed for atmospheric conditions) towards use with elevated pressure therefore a couple of modifications had to be applied to the subroutine responsible for calculation of solids distribution. In addition a new module had to be written, for the computation of gas properties of air and flue gas at pressures up to 50 bar and temperatures up to 1200 C to prevent inaccuracies when extending simulation to pressures above 16 bar. This module utilizes a 1-fluid-approximation for an arbitrary mixture of N{sub 2}, O{sub 2}, CO{sub 2}, SO{sub 2}, H{sub 2}O and Ar, gas properties are computed by using mainly the Lee-Kesler-Pitzer approach for real gas-effects. Computations were performed with this software to demonstrate trends in fluidization behavior at higher than atmospheric pressures. A model of a pressurized system was compared to an AFB at the same superficial velocity, reaching similar fluidization states by enlarging the bed mass at higher pressures. These numeric tests were run for pressures of 10 and 20 bar. (orig.)

  16. Hyolaryngeal excursion as the physiological source of swallowing accelerometry signals

    International Nuclear Information System (INIS)

    Zoratto, D C B; Chau, T; Steele, C M

    2010-01-01

    Swallowing dysfunction, or dysphagia, is a serious condition that can result from any structural or neurological impairment (such as stroke, neurodegenerative disease or brain injury) that affects the swallowing mechanism. The gold-standard method of instrumental swallowing assessment is an x-ray examination known as the videofluoroscopic swallowing study, which involves radiation exposure. Consequently, there is interest in exploring the potential of less invasive methods, with lesser risks of biohazard, to accurately detect swallowing abnormalities. Accelerometry is one such technique, which measures the epidermal vibration signals on a patient's neck during swallowing. Determining the utility of accelerometry signals for detecting dysphagia requires an understanding of the physiological source of the vibrations that are measured on the neck during swallowing. The purpose of the current study was to determine the extent to which movement of the hyoid bone and larynx contributes to the vibration signal that is registered during swallowing accelerometry. This question was explored by mapping the movement trajectories of the hyoid bone and the arytenoid cartilages from lateral videofluoroscopy recordings collected during thin liquid swallowing, and comparing these trajectories to time-linked signals obtained from a dual-axis accelerometer placed on the neck, just anterior to the cricoid cartilage. Participants for this study included 43 adult patients referred for videofluoroscopic swallowing studies to characterize the nature and severity of suspected neurogenic dysphagia. A software program was created to allow frame-by-frame tracking of structural movement on the videofluoroscopy recordings. These movement data were then compared to the integrated acceleration data using multiple linear regressions. The results concur with previous studies, implicating hyolaryngeal excursion as the primary physiological source of swallowing accelerometry signals, with both

  17. Utilizing Photogrammetry and Strain Gage Measurement to Characterize Pressurization of Inflatable Modules

    Science.gov (United States)

    Mohammed, Anil

    2011-01-01

    This paper focuses on integrating a large hatch penetration into inflatable modules of various constructions. This paper also compares load predictions with test measurements. The strain was measured by utilizing photogrammetric methods and strain gages mounted to select clevises that interface with the structural webbings. Bench testing showed good correlation between strain data collected from an extensometer and photogrammetric measurements, even when the material transitioned from the low load to high load strain region of the curve. The full-scale torus design module showed mixed results as well in the lower load and high strain regions. After thorough analysis of photogrammetric measurements, strain gage measurements, and predicted load, the photogrammetric measurements seem to be off by a factor of two.

  18. Laboratory Measures of Postural Control During the Star Excursion Balance Test After Acute First-Time Lateral Ankle Sprain

    Science.gov (United States)

    Doherty, Cailbhe; Bleakley, Chris M.; Hertel, Jay; Caulfield, Brian; Ryan, John; Delahunt, Eamonn

    2015-01-01

    Context No researchers, to our knowledge, have investigated the immediate postinjury-movement strategies associated with acute first-time lateral ankle sprain (LAS) as quantified by center of pressure (COP) and kinematic analyses during performance of the Star Excursion Balance Test (SEBT). Objective To analyze the kinematic and COP patterns of a group with acute first-time LAS and a noninjured control group during performance of the SEBT. Design Case-control study. Setting University biomechanics laboratory. Patients or Other Participants A total of 81 participants with acute first-time LAS (53 men, 28 women; age = 23.22 ± 4.93 years, height = 1.73 ± 0.09 m, mass = 75.72 ± 13.86 kg) and 19 noninjured controls (15 men, 4 women; age = 22.53 ± 1.68 years, height = 1.74 ± 0.08 m, mass = 71.55 ± 11.31 kg). Intervention Participants performed the anterior (ANT), posterolateral (PL), and posteromedial (PM) reach directions of the SEBT. Main Outcome Measure(s) We assessed 3-dimensional kinematics of the lower extremity joints and associated fractal dimension (FD) of the COP path during performance of the SEBT. Results The LAS group had decreased normalized reach distances in the ANT, PL, and PM directions when compared with the control group on their injured (ANT: 58.16% ± 6.86% versus 64.86% ± 5.99%; PL: 85.64% ± 10.62% versus 101.14% ± 8.39%; PM: 94.89% ± 9.26% versus 107.29 ± 6.02%) and noninjured (ANT: 60.98% ± 6.74% versus 64.76% ± 5.02%; PL: 88.95% ± 11.45% versus 102.36% ± 8.53%; PM: 97.13% ± 8.76% versus 106.62% ± 5.78%) limbs (P postural control, as evidenced by the bilateral reduction in angular displacement of the lower extremity joints and reduced reach distances and FD of the COP path on the injured limb during performance of the SEBT. PMID:25811845

  19. Evaluation of postprandial glucose excursion using a novel minimally invasive glucose area-under-the-curve monitoring system.

    Science.gov (United States)

    Kuranuki, Sachi; Sato, Toshiyuki; Okada, Seiki; Hosoya, Samiko; Seko, Akinobu; Sugihara, Kaya; Nakamura, Teiji

    2013-01-01

    To develop a minimally invasive interstitial fluid extraction technology (MIET) to monitor postprandial glucose area under the curve (AUC) without blood sampling, we evaluated the accuracy of glucose AUC measured by MIET and compared with that by blood sampling after food intake. Interstitial fluid glucose AUC (IG-AUC) following consumption of 6 different types of foods was measured by MIET. MIET consisted of stamping microneedle arrays, placing hydrogel patches on the areas, and calculating IG-AUC based on glucose levels in the hydrogels. Glycemic index (GI) was determined using IG-AUC and reference AUC measured by blood sampling. IG-AUC strongly correlated with reference AUC (R = 0.91), and GI determined using IG-AUC showed good correlation with that determined by reference AUC (R = 0.88). IG-AUC obtained by MIET can accurately predict the postprandial glucose excursion without blood sampling. In addition, feasibility of GI measurement by MIET was confirmed.

  20. Trajectory of coronary motion and its significance in robotic motion cancellation.

    Science.gov (United States)

    Cattin, Philippe; Dave, Hitendu; Grünenfelder, Jürg; Szekely, Gabor; Turina, Marko; Zünd, Gregor

    2004-05-01

    To characterize remaining coronary artery motion of beating pig hearts after stabilization with an 'Octopus' using an optical remote analysis technique. Three pigs (40, 60 and 65 kg) underwent full sternotomy after receiving general anesthesia. An 8-bit high speed black and white video camera (50 frames/s) coupled with a laser sensor (60 microm resolution) were used to capture heart wall motion in all three dimensions. Dopamine infusion was used to deliberately modulate cardiac contractility. Synchronized ECG, blood pressure, airway pressure and video data of the region around the first branching point of the left anterior descending (LAD) coronary artery after Octopus stabilization were captured for stretches of 8 s each. Several sequences of the same region were captured over a period of several minutes. Computerized off-line analysis allowed us to perform minute characterization of the heart wall motion. The movement of the points of interest on the LAD ranged from 0.22 to 0.81 mm in the lateral plane (x/y-axis) and 0.5-2.6 mm out of the plane (z-axis). Fast excursions (>50 microm/s in the lateral plane) occurred corresponding to the QRS complex and the T wave; while slow excursion phases (movement of the coronary artery after stabilization appears to be still significant. Minute characterization of the trajectory of motion could provide the substrate for achieving motion cancellation for existing robotic systems. Velocity plots could also help improve gated cardiac imaging.

  1. The making of pressure measurement device on heating-02 based realtime

    International Nuclear Information System (INIS)

    Giarno; Kussigit Santosa; Agus Nur Rachman; G B Heru K

    2013-01-01

    In order to modify the installation strand BETA Test Section Test integrated with heating-02 into a closed loop, it would require an additional system that can measure pressure changes in the closed-loop system. By making the measurement device to test the system pressure at the heating-expected 02 researchers can monitor the pressure changes that occur in the system. The pressure gauge device fabrication using manufacturing simulation methodology, the preparation of the hardware and software and test functions. Manufacturing simulation using measuring devices HIOKI DC current source Signal Source, preparation of pressure measurement devices require hardware such as pressure transducers, NI cRIO-9074, NI 9203 analog module, Computer and software LabVIEW 2011 as programming. In the test process function method is used to provide flow simulation module that is connected to the 9203 NI NI cRIO-9074. Current provision tailored to the specifics pressure transducer is 4 mA s/d 20 mA. Based on the test results obtained function value of the lowest current is 4.00 mA = 0.001 bar, and the highest current value of 20.00 mA = 4995 bar. From the results of calculations using the linear equations obtained correlation coefficient (R 2 ) of 0.999, so it is evident that the pressure changes in LabVIEW is affected by changes in flow. The results obtained from this activity is a device that can measure the pressure in the heating-02 test. (author)

  2. Quality Assurance Tests of the LHCb VELO Modules

    CERN Document Server

    Marinho, Franciole

    2007-01-01

    The LHCb experiment has a dedicated vertex detector (VELO) to measure the particle’s tracks close to the interaction point. This paper describes the main steps of the quality assurance tests performed during assembly, reception and installation of the LHCb VELO modules. Visual inspection, electrical tests, thermal tests and metrology measurements were made. A burn-in test of the modules was performed in a vacuum environment similar to that of the LHCb experiment. The signal to noise of the sensors was estimated to be 20.4 3.0 for R sensors and 22.4 3 0 for Φ sensors. The modules were tested up to 350 V and the leakage current of the modules did not exceed 20µA at any stage of the testing. Only 0.6% of channels were found to be noisy or not fully functional. The acceptable operating pressures of the modules in vacuum was also evaluated.

  3. The Manufacturing Process for the NASA Composite Crew Module Demonstration Structure

    Science.gov (United States)

    Pelham, Larry; Higgins, John E.

    2008-01-01

    This paper will describe the approaches and methods selected in fabrication of a carbon composite demonstration structure for the Composite Crew Module (CCM) Program. The program is managed by the NASA Safety and Engineering Center with participants from ten NASA Centers and AFRL. Multiple aerospace contractors are participating in the design development, tooling and fabrication effort as well. The goal of the program is to develop an agency wide design team for composite habitable spacecraft. The specific goals for this development project are: a).To gain hands on experience in design, building and testing a composite crew module. b) To validate key assumptions by resolving composite spacecraft design details through fabrication and testing of hardware. This abstract is based on Preliminary Design data..The final design will continue to evolve through the fall of 2007 with fabrication mostly completed by conference date. From a structures perspective, the.CCM can be viewed as a pressure module with variable pressure time histories and a series of both impact and quasi-static, high intensity point, line, and area distributed loads. The portion of the overall space vehicle being designed and. fabricated by the CCM team is just the pressure module and primary loading points. The heaviest point loads are applied and distributed to the pressure module at.an aluminum Service Module/Alternate Launch Abort System (SM/ALAS) fittings and at Main and Drogue Chute fittings. Significant line loads with metal to metal impact is applied at.the Lids ring. These major external point and line loads as well as pressure impact loads (blast and water landing) are applied to the lobed floor though the reentry shield and crushable materials. The pressure module is divided into upper and lower. shells that mate together with a bonded belly band splice joint to create the completed structural assembly. The benefits of a split CCM far outweigh the risks of a joint. These benefits include

  4. Development of user-friendly structural design system for pressure vessels

    International Nuclear Information System (INIS)

    Sato, Takuya; Nomoto, Taeko; Kado, Kenichiro; Yagawa, Genki; Yoshimura, Shinobu.

    1996-01-01

    In this paper we describe a new user-friendly structural design system for pressure vessels, which is based on finite element stress analyses. The basic concept of the developed system is to minimize input data required for the finite element analysis and to perform the analysis quickly. To realize this, the system is equipped with the finite element modeling module based on fuzzy knowledge processing, the input data generation module, the finite element analyzer, the graphic user-interface module for analysis results, and the stress evaluation module. Fundamental performance of the present system is clearly demonstrated through the analysis of a top nozzle. (author)

  5. Investigation of coolant mixture in pressurized water reactors at the Rossendorf mixing test facility ROCOM

    International Nuclear Information System (INIS)

    Grunwald, G.; Hoehne, T.; Prasser, H.M.; Richter, K.; Weiss, F.P.

    1999-01-01

    During the so-called boron dilution or cold water transients at pressurized water reactors too weakly borated water or too cold water, respectively, might enter the reactor core. This results in the insertion of positive reactivity and possibly leads to a power excursion. If the source of unborated or subcooled water is not located in all coolant loops but in selected ones only, the amount of reactivity insertion depends on the coolant mixing in the downcomer and lower plenum of the reactor pressure vessel (RPV). Such asymmetric disturbances of the coolant temperature or boron concentration might e.g. be the result of a failure of the chemical and volume control system (CVCS) or of a main steam line break (MSLB) that does only affect selected steam generators (SG). For the analysis of boron dilution or MSLB accidents coupled neutron kinetics/thermo-hydraulic system codes have been used. To take into account coolant mixing phenomena in these codes in a realistic manner, analytical mixing models might be included. These models must be simple and fast running on the one hand, but must well describe the real mixing conditions on the other hand. (orig.)

  6. Evaluation of PV modules integrated with roofing materials; Kenzai ittaigata taiyo denchi module no hyoka

    Energy Technology Data Exchange (ETDEWEB)

    Morizane, M.; Yagiura, T.; Nakashima, S.; Yagi, H.; Murata, K.; Uchihashi, K.; Tsuda, S.; Nakano, S. [Sanyo Electric Co. Ltd., Osaka (Japan); Ito, M.; Kurimoto, T.; Yamakawa, H.; Fujiwara, T. [Kubota Corp., Osaka (Japan)

    1997-11-25

    PV modules unified with building materials which are low in cost, easy to install and excellent in designing were developed and were evaluated in various tests. As to the basic structure of this module, seamless and unified construction with the back metal plate was adopted considering improvement in fire prevention and cost reduction. About the installation, module is easy to install by just fit connection with the frame, and easy to remove with no use of special tools. Concerning intensity and durability requested for this module, tests on reliability such as torsion strength and wind pressure resistance were conducted according to JIS standards, and it was confirmed that there were no problems. Also on the long-term durability, tests on long-term reliability were carried out by doubling test terms of the temperature/humidity cycle test, salt water resistance test, etc., and the reliability the same as that of the existing type was confirmed. In the verification test using a model house, no changes were seen in electrical characteristics and appearance, and waterproof was also favorable one and a half year after the installation. 4 refs., 7 figs., 5 tabs.

  7. Analyses of the mechanisms of amplitude modulation of aero-acoustic wind turbine sound

    DEFF Research Database (Denmark)

    Fischer, Andreas; Aagaard Madsen, Helge; Kragh, Knud Abildgaard

    2014-01-01

    This paper explores the source mechanism which cause amplitude modulation of the emitted sound of a wind turbine at large distances from the turbine, named as other amplitude modulation. Measurements of the fluctuating surface pressure on a 2.3MW wind turbine showed a considerable variation over...... give further evidence that transient stall is a main mechanism to cause other amplitude modulation. Wind shear was identified as a critical condition to cause angle of attack variations. Dierent control strategies to mitigate other amplitude modulation were proposed....

  8. About the causes and circumstances of the Chernobyl NPP accident

    International Nuclear Information System (INIS)

    Shteynberg, N.

    1992-01-01

    The Chernobyl accident is the product of unsatisfactory solutions to scientific-technical, socio-economic and human problems. The documentarily recorded power excursion of the reactor and its rise velocity as well as the quick pressure rise in the separator drum admit the conclusion that the cause of the accident was the rapid power excursion of the reactor and not some external influence. (DG) [de

  9. Development of Thermal-hydraulic Analysis Methodology for Multi-module Breeding Blankets in K-DEMO

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Geon-Woo; Lee, Jeong-Hun; Park, Goon-Cherl; Cho, Hyoung-Kyu [Seoul National University, Seoul (Korea, Republic of); Im, Kihak [National Fusion Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    In this paper, the purpose of the analyses is to extend the capability of MARS-KS to the entire blanket system which includes a few hundreds of single blanket modules. Afterwards, the plan for the whole blanket system analysis using MARS-KS is introduced and the result of the multiple blanket module analysis is summarized. A thermal-hydraulic analysis code for a nuclear reactor safety, MARS-KS, was applied for the conceptual design of the K-DEMO breeding blanket thermal analysis. Then, a methodology to simulate multiple blanket modules was proposed, which uses a supervisor program to handle each blanket module individually at first and then distribute the flow rate considering pressure drops arises in each module. For a feasibility test of the proposed methodology, 10 outboard blankets in a toroidal field sector were simulated, which are connected with each other through the inlet and outlet common headers. The calculation results of flow rates, pressure drops, and temperatures showed the validity of the calculation and thanks to the parallelization using MPI, almost linear speed-up could be obtained.

  10. Liquid pressure wireless sensor based on magnetostrictive microwires for applications in cardiovascular localized diagnostic

    Directory of Open Access Journals (Sweden)

    A. M. Aragón

    2015-08-01

    Full Text Available In this letter, we report a method to measure changes in a fluid pressure, flowing through a flexible pipeline, by means of a ring of magnetic microwire concentric to the pipeline. The detection is based on the modulated scattering of electromagnetic waves by the magnetoelastic ring. This modulation is driven by applying a low frequency bias magnetic field able to tune the magnetic permeability of the ferromagnetic microwire. Pressure detection, by means of magnetic permeability changes, is possible due to the magnetostrictive character of the sample. The experimental work developed has, also, allowed fluid pressure detection in a hydraulic circuit connected to ventricular assist system where a fluid with a viscosity close to blood flows.

  11. Development of high pressure pipe scanners

    International Nuclear Information System (INIS)

    Kim, Jae H.; Lee, Jae C.; Moon, Soon S.; Eom, Heung S.; Choi, Yu R.

    1998-12-01

    This report describes an automatic ultrasonic scanning system for pressure pipe welds, which was developed in this project using recent advanced technologies on mobile robot and computer. The system consists of two modules: a robot scanner module which navigates and manipulates scanning devices, and a data acquisition module which generates ultrasonic signal and processes the data from the scanner. The robot has 4 magnetic wheels and 2 -axis manipulator on which ultrasonic transducer attached. The wheeled robot can navigate curved surface such as outer wall of circular pipes. Magnetic wheels were optimally designed through magnetic field analysis. Free surface sensing and line tracking control algorithm were developed and implemented, and the control devices and software can be used in practical inspection works. We expect our system can contribute to reduction of inspection time, performance enhancement, and effective management of inspection results

  12. Atmospheric pressure plasma analysis by modulated molecular beam mass spectrometry

    NARCIS (Netherlands)

    Aranda Gonzalvo, Y.; Whitmore, T.D.; Rees, J.A.; Seymour, D.L.; Stoffels - Adamowicz, E.

    2006-01-01

    Fractional no. d. measurements for a radiofrequency plasma needle operating at atm. pressure were obtained using a mol. beam mass spectrometer (MBMS) system designed for diagnostics of atm. plasmas. The MBMS system comprises three differentially pumped stages and a mass/energy analyzer and includes

  13. Right ventricular pressure response to exercise in adults with isolated ventricular septal defect closed in early childhood.

    Science.gov (United States)

    Moller, Thomas; Lindberg, Harald; Lund, May Brit; Holmstrom, Henrik; Dohlen, Gaute; Thaulow, Erik

    2018-06-01

    We previously demonstrated an abnormally high right ventricular systolic pressure response to exercise in 50% of adolescents operated on for isolated ventricular septal defect. The present study investigated the prevalence of abnormal right ventricular systolic pressure response in 20 adult (age 30-45 years) patients who underwent surgery for early ventricular septal defect closure and its association with impaired ventricular function, pulmonary function, or exercise capacity. The patients underwent cardiopulmonary tests, including exercise stress echocardiography. Five of 19 patients (26%) presented an abnormal right ventricular systolic pressure response to exercise ⩾ 52 mmHg. Right ventricular systolic function was mixed, with normal tricuspid annular plane systolic excursion and fractional area change, but abnormal tricuspid annular systolic motion velocity (median 6.7 cm/second) and isovolumetric acceleration (median 0.8 m/second2). Left ventricular systolic and diastolic function was normal at rest as measured by the peak systolic velocity of the lateral wall and isovolumic acceleration, early diastolic velocity, and ratio of early diastolic flow to tissue velocity, except for ejection fraction (median 53%). The myocardial performance index was abnormal for both the left and right ventricle. Peak oxygen uptake was normal (mean z score -0.4, 95% CI -2.8-0.3). There was no association between an abnormal right ventricular systolic pressure response during exercise and right or left ventricular function, pulmonary function, or exercise capacity. Abnormal right ventricular pressure response is not more frequent in adult patients compared with adolescents. This does not support the theory of progressive pulmonary vascular disease following closure of left-to-right shunts.

  14. Evaluation of Postprandial Glucose Excursion Using a Novel Minimally Invasive Glucose Area-Under-the-Curve Monitoring System

    Directory of Open Access Journals (Sweden)

    Sachi Kuranuki

    2013-01-01

    Full Text Available Objective: To develop a minimally invasive interstitial fluid extraction technology (MIET to monitor postprandial glucose area under the curve (AUC without blood sampling, we evaluated the accuracy of glucose AUC measured by MIET and compared with that by blood sampling after food intake. Methods: Interstitial fluid glucose AUC (IG-AUC following consumption of 6 different types of foods was measured by MIET. MIET consisted of stamping microneedle arrays, placing hydrogel patches on the areas, and calculating IG-AUC based on glucose levels in the hydrogels. Glycemic index (GI was determined using IG-AUC and reference AUC measured by blood sampling. Results: IG-AUC strongly correlated with reference AUC (R = 0.91, and GI determined using IG-AUC showed good correlation with that determined by reference AUC (R = 0.88. Conclusions: IG-AUC obtained by MIET can accurately predict the postprandial glucose excursion without blood sampling. In addition, feasibility of GI measurement by MIET was confirmed.

  15. Radiation-pressure-mediated control of an optomechanical cavity

    Science.gov (United States)

    Cripe, Jonathan; Aggarwal, Nancy; Singh, Robinjeet; Lanza, Robert; Libson, Adam; Yap, Min Jet; Cole, Garrett D.; McClelland, David E.; Mavalvala, Nergis; Corbitt, Thomas

    2018-01-01

    We describe and demonstrate a method to control a detuned movable-mirror Fabry-Pérot cavity using radiation pressure in the presence of a strong optical spring. At frequencies below the optical spring resonance, self-locking of the cavity is achieved intrinsically by the optomechanical (OM) interaction between the cavity field and the movable end mirror. The OM interaction results in a high rigidity and reduced susceptibility of the mirror to external forces. However, due to a finite delay time in the cavity, this enhanced rigidity is accompanied by an antidamping force, which destabilizes the cavity. The cavity is stabilized by applying external feedback in a frequency band around the optical spring resonance. The error signal is sensed in the amplitude quadrature of the transmitted beam with a photodetector. An amplitude modulator in the input path to the cavity modulates the light intensity to provide the stabilizing radiation pressure force.

  16. Numerical Studies on the Effects of the Channel-Inlet-Pressure Difference in the Pressure-Retarded Osmosis (PRO) Power System

    International Nuclear Information System (INIS)

    Hong, Sung Soo; Ryoo, Won; Chung, Gui Yung; Chun, Myung-Suk

    2014-01-01

    In the spiral wound module of the pressure-retarded osmosis (PRO) system for the salinity gradient power generation, effects of the inlet pressure differences between feed-channel and draw-channel were studied. Fluxes of water and solute through membrane and power were estimated. The water flux through membrane decreased along the x-direction and increased along the y-direction with the increase of inlet pressure differences between two channels. On the other hand, the solute flux through membrane showed the opposite trend. The concentration of flow in the feed-channel increased a lot along the y-direction and that in the draw-channel decreased along the x-direction. In our system, for the inlet pressure differences of 1-11 atm, the flow rate in the feed-channel decreased about 8-13% and that in the draw-channel increased by the same amount. The power density increased and then decreased with the increasing inlet pressure difference

  17. Numerical Studies on the Effects of the Channel-Inlet-Pressure Difference in the Pressure-Retarded Osmosis (PRO) Power System

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Sung Soo; Ryoo, Won; Chung, Gui Yung [Hong-Ik University, Seoul (Korea, Republic of); Chun, Myung-Suk [Korea Institute of Science and Technology (KIST), Seoul (Korea, Republic of)

    2014-02-15

    In the spiral wound module of the pressure-retarded osmosis (PRO) system for the salinity gradient power generation, effects of the inlet pressure differences between feed-channel and draw-channel were studied. Fluxes of water and solute through membrane and power were estimated. The water flux through membrane decreased along the x-direction and increased along the y-direction with the increase of inlet pressure differences between two channels. On the other hand, the solute flux through membrane showed the opposite trend. The concentration of flow in the feed-channel increased a lot along the y-direction and that in the draw-channel decreased along the x-direction. In our system, for the inlet pressure differences of 1-11 atm, the flow rate in the feed-channel decreased about 8-13% and that in the draw-channel increased by the same amount. The power density increased and then decreased with the increasing inlet pressure difference.

  18. Simulation of the pressure recovery time in a CLIC standard module

    CERN Document Server

    Costa-Pinto, P

    2008-01-01

    Vacuum pressure inside the CLIC accelerating structures (AS) is crucial for both beam and RF stability. Gas molecules released during RF breakdown must be evacuated from the cells of the AS before the arrival of the next train of particles. Due to its complex geometry, accurate analytical calculations are not viable. In this paper we introduce a calculation method based on the combination of analytical vacuum equations with Monte Carlo test particle simulations, implemented in a PSpice environment via the vacuum-electrical network analogy. Pressure recovery times are calculated for the main gas species released during a breakdown. The number and type of molecules used for the calculation is the result of measurements performed in the DC spark test system.

  19. Effect of power modulation on properties of pulsed capacitively coupled radiofrequency discharges

    International Nuclear Information System (INIS)

    Samara, V; Bowden, M D; Braithwaite, N St J

    2010-01-01

    We describe measurements of plasma properties of pulsed, low pressure, capacitively coupled discharges operated in argon. The study aims to determine the effect of modulating the radiofrequency power during the discharge part of the pulse cycle. Measurements of local electron density and optical emission were made in capacitively coupled rf discharges generated in a Gaseous Electronics Conference (GEC) reference reactor. Gas pressure was in the range 7-70 Pa, rf power in the range 1-100 W and pulse durations in the range 10 μs-100 ms. The results indicate that the ignition and afterglow decay processes in pulsed discharges can be controlled by modulating the shape of applied radiofrequency pulse.

  20. Relation of Dietary Sodium (Salt) to Blood Pressure and Its Possible Modulation by Other Dietary Factors: The INTERMAP Study.

    Science.gov (United States)

    Stamler, Jeremiah; Chan, Queenie; Daviglus, Martha L; Dyer, Alan R; Van Horn, Linda; Garside, Daniel B; Miura, Katsuyuki; Wu, Yangfeng; Ueshima, Hirotsugu; Zhao, Liancheng; Elliott, Paul

    2018-04-01

    Available data indicate that dietary sodium (as salt) relates directly to blood pressure (BP). Most of these findings are from studies lacking dietary data; hence, it is unclear whether this sodium-BP relationship is modulated by other dietary factors. With control for multiple nondietary factors, but not body mass index, there were direct relations to BP of 24-hour urinary sodium excretion and the urinary sodium/potassium ratio among 4680 men and women 40 to 59 years of age (17 population samples in China, Japan, United Kingdom, and United States) in the INTERMAP (International Study on Macro/Micronutrients and Blood Pressure), and among its 2195 American participants, for example, 2 SD higher 24-hour urinary sodium excretion (118.7 mmol) associated with systolic BP 3.7 mm Hg higher. These sodium-BP relations persisted with control for 13 macronutrients, 12 vitamins, 7 minerals, and 18 amino acids, for both sex, older and younger, blacks, Hispanics, whites, and socioeconomic strata. With control for body mass index, sodium-BP-but not sodium/potassium-BP-relations were attenuated. Normal weight and obese participants manifested significant positive relations to BP of urinary sodium; relations were weaker for overweight people. At lower but not higher levels of 24-hour sodium excretion, potassium intake blunted the sodium-BP relation. The adverse association of dietary sodium with BP is minimally attenuated by other dietary constituents; these findings underscore the importance of reducing salt intake for the prevention and control of prehypertension and hypertension. URL: https://www.clinicaltrials.gov. Unique identifier: NCT00005271. © 2018 American Heart Association, Inc.

  1. Local blockage of EMMPRIN impedes pressure ulcers healing in a rat model

    OpenAIRE

    Zhao, Xi-Lan; Luo, Xiao; Wang, Ze-Xin; Yang, Guo-Li; Liu, Ji-Zhong; Liu, Ya-Qiong; Li, Ming; Chen, Min; Xia, Yong-Mei; Liu, Jun-Jie; Qiu, Shu-Ping; Gong, Xiao-Qing

    2015-01-01

    Excessive extracellular matrix degradation caused by the hyperfunction of matrix metalloproteinases (MMPs) has been implicated in the failure of pressure ulcers healing. EMMPRIN, as a widely expressed protein, has emerged as an important regulator of MMP activity. We hypothesize that EMMPRIN affects the process of pressure ulcer healing by modulating MMP activity. In the rat pressure ulcer model, the expression of EMMPRIN in ulcers detected by Western blot was elevated compared with that obse...

  2. Magnetic structures of erbium under high pressure

    DEFF Research Database (Denmark)

    Kawano, S.; Lebech, B.; Achiwa, N.

    1993-01-01

    Neutron diffraction studies of the magnetic structures of erbium metal at 4.5 K and 11.5 kbar hydrostatic pressure have revealed that the transition to a conical structure at low temperatures is suppressed and that the cycloidal structure, with modulation vector Q congruent-to (2/7 2pi/c)c persists...

  3. Shape control of slack space reflectors using modulated solar pressure.

    Science.gov (United States)

    Borggräfe, Andreas; Heiligers, Jeannette; Ceriotti, Matteo; McInnes, Colin R

    2015-07-08

    The static deflection profile of a large spin-stabilized space reflector because of solar radiation pressure acting on its surface is investigated. Such a spacecraft consists of a thin reflective circular film, which is deployed from a supporting hoop structure in an untensioned, slack manner. This paper investigates the use of a variable reflectivity distribution across the surface to control the solar pressure force and hence the deflected shape. In this first analysis, the film material is modelled as one-dimensional slack radial strings with no resistance to bending or transverse shear, which enables a semi-analytic derivation of the nominal deflection profile. An inverse method is then used to find the reflectivity distribution that generates a specific, for example, parabolic deflection shape of the strings. Applying these results to a parabolic reflector, short focal distances can be obtained when large slack lengths of the film are employed. The development of such optically controlled reflector films enables future key mission applications such as solar power collection, radio-frequency antennae and optical telescopes.

  4. Development of thermal-hydraulic analysis methodology for multiple modules of water-cooled breeder blanket in fusion DEMO reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Geon-Woo; Lee, Jeong-Hun [Department of Nuclear Engineering, Seoul National University 1 Gwanak-ro, Gwanak-gu, Seoul 151-744 (Korea, Republic of); Cho, Hyoung-Kyu, E-mail: chohk@snu.ac.kr [Department of Nuclear Engineering, Seoul National University 1 Gwanak-ro, Gwanak-gu, Seoul 151-744 (Korea, Republic of); Park, Goon-Cherl [Department of Nuclear Engineering, Seoul National University 1 Gwanak-ro, Gwanak-gu, Seoul 151-744 (Korea, Republic of); Im, Kihak [National Fusion Research Institute, 169-148, Yuseong-gu, Daejeon 305-806 (Korea, Republic of)

    2016-02-15

    Highlights: • A methodology to simulate the K-DEMO blanket system was proposed. • The results were compared with the CFD, to verify the prediction capability of MARS. • 46 Blankets in a single sector in K-DEMO were simulated using MARS-KS. • Supervisor program was devised to handle each blanket module individually. • The calculation results showed the flow rates, pressure drops, and temperatures. - Abstract: According to the conceptual design of the fusion DEMO reactor proposed by the National Fusion Research Institute of Korea, the water-cooled breeding blanket system incorporates a total of 736 blanket modules. The heat flux and neutron wall loading to each blanket module vary along their poloidal direction, and hence, thermal analysis for at least one blanket sector is required to confirm that the temperature limitations of the materials are satisfied in all the blanket modules. The present paper proposes a methodology of thermal analysis for multiple modules of the blanket system using a nuclear reactor thermal-hydraulic analysis code, MARS-KS. In order to overcome the limitations of the code, caused by the restriction on the number of computational nodes, a supervisor program was devised, which handles each blanket module separately at first, and then corrects the flow rate, considering pressure drops that occur in each module. For a feasibility test of the proposed methodology, 46 blankets in a single sector were simulated; the calculation results of the parameters, such as mass flow, pressure drops, and temperature distribution in the multiple blanket modules showed that the multi-module analysis method can be used for efficient thermal-hydraulic analysis of the fusion DEMO reactor.

  5. Are U-channels measurements appropriate for reversal or excursion records ?

    Science.gov (United States)

    Philippe, E. G. H.; Valet, J. P.

    2017-12-01

    Sampling of sediment cores by U-channel plastic tubes is a very successful technique that allows to perform measurements of the magnetic remanence and demagnetization of long sections of sediment. This approach made possible the acquisition of detailed records of paleosecular variation, geomagnetic polarity and relative paleointensity over the past million years and yielded significant advances in our knowledge of the geomagnetic field changes. The major pitfall is that the resolution of the signal which is imposed by the deposition rate of the sediment is also attenuated by the response curve of the magnetic sensors used for measurements. This is not so critical to document the dipole field changes, but may have a significant impact to recover fast field changes typical of the non-dipole field that prevail during reversals and excursions. We have investigated possible consequences by comparing 150 successive individual directions of 1 cm side successive single samples with the measurement of the 1.5m equivalent U-channel obtained by placing the same samples adjacent to each other. We compared different transition lengths and generated transitional directions that produce records with similar characteristics as those derived from volcanic records of reversals with a magnetization intensity dropping to 5% of the full polarity value during the transition. The results show that even with transitional intervals as long as 30 cm and therefore associated with deposition rates as high as 10 cm/ka the U-channels considerably smooth all variations with significant consequences on the VGP paths that become more constrained in longitude. Despite little similarity with the global structure of the transition, the U-channels fail to reproduce the complexity of the transitional period. The transitional VGPs never duplicate the variations of the non-dipole field even within several centimeters and generate artificial clusters or periods of apparent fast changes. We are currently

  6. A critical note on the IAGA-endorsed Polar Cap (PC) indices: excessive excursions in the real-time index values

    Science.gov (United States)

    Stauning, Peter

    2018-04-01

    The Polar Cap (PC) indices were approved by the International Association for Geomagnetism and Aeronomy (IAGA) in 2013 and made available at the web portal http://pcindex.org" target="_blank">http://pcindex.org holding prompt (real-time) as well as archival index values. The present note provides the first reported examination of the validity of the IAGA-endorsed method to generate real-time PC index values. It is demonstrated that features of the derivation procedure defined by Janzhura and Troshichev (2011) may cause considerable excursions in the real-time PC index values compared to the final index values. In examples based on occasional downloads of index values, the differences between real-time and final values of PC indices were found to exceed 3 mV m-1, which is a magnitude level that may indicate (or hide) strong magnetic storm activity.

  7. Environmental testing of terrestrial flat plate photovoltaic modules

    Science.gov (United States)

    Hoffman, A.; Griffith, J.

    1979-01-01

    The Low-Cost Solar Array (LSA) Project at the Jet Propulsion Laboratory has as one objective: the development and implementation of environmental tests for flat plate photovoltaic modules as part of the Department of Energy's terrestrial photovoltaic program. Modules procured under this program have been subjected to a variety of laboratory tests intended to simulate service environments, and the results of these tests have been compared to available data from actual field service. This comparison indicates that certain tests (notably temperature cycling, humidity cycling, and cyclic pressure loading) are effective indicators of some forms of field failures. Other tests have yielded results useful in formulating module design guidelines. Not all effects noted in field service have been successfully reproduced in the laboratory, however, and work is continuing in order to improve the value of the test program as a tool for evaluating module design and workmanship. This paper contains a review of these ongoing efforts and an assessment of significant test results to date.

  8. Optimal right heart filling pressure in acute respiratory distress syndrome determined by strain echocardiography.

    Science.gov (United States)

    Garcia-Montilla, Romel; Imam, Faryal; Miao, Mi; Stinson, Kathryn; Khan, Akram; Heitner, Stephen

    2017-06-01

    Right ventricular (RV) systolic dysfunction is common in acute respiratory distress syndrome (ARDS). While preload optimization is crucial in its management, dynamic fluid responsiveness indices lack reliability, and there is no consensus on target central venous pressure (CVP). We analyzed the utility of RV free wall longitudinal strain (RVFWS) in the estimation of optimal RV filling pressure in ARDS. A retrospective cross-sectional analysis of clinical data and echocardiograms of patients with ARDS was performed. Tricuspid annular plane systolic excursion (TAPSE), tricuspid peak systolic velocity (S'), RV fractional area change (RVFAC), RVFWS, CVP, systolic pulmonary artery pressure (SPAP), and left ventricular ejection fraction (LVEF) were measured. Fifty-one patients with moderate-severe ARDS were included. There were inverse correlations between CVP and TAPSE, S', RVFAC, RVFWS, and LVEF. The most significant was with RVFWS (r:.74, R 2 :.55, P:.00001). Direct correlations with creatinine and lactate were noted. Receiver operating characteristic analysis showed that RVFWS -21% (normal reference value) was associated with CVP: 13 mm Hg (AUC: 0.92, 95% CI: 0.83-1.00). Regression model analysis of CVP, and RVFWS interactions established an RVFWS range from -18% to -24%. RVFWS -24% corresponded to CVP: 11 mm Hg and RVFWS -18% to CVP: 15 mm Hg. Beyond a CVP of 15 mm Hg, biventricular systolic dysfunction rapidly ensues. Our data are the first to show that an RV filling pressure of 13±2 mm Hg-as by CVP-correlates with optimal RV mechanics as evaluated by strain echocardiography in patients with moderate-severe ARDS. © 2017, Wiley Periodicals, Inc.

  9. Investigation of high flux test module for the international fusion materials irradiation facilities (IFMIF)

    International Nuclear Information System (INIS)

    Miyashita, Makoto; Sugimoto, Masayoshi; Yutani, Toshiaki

    2007-03-01

    This report describes investigation on structure of a high neutron flux test module (HFTM) for the International Fusion Materials Irradiation Facilities (IFMIF). The HFTM is aimed for neutron irradiation of a specimen in a high neutron flux domain of the test cell for irradiation ground of IFMIF. We investigated the overall structure of the HFTM that was able to include specimens in a rig and thermocouple arrangement, an interface of control signal and support structure. Moreover, pressure and the amount of the bend in the module vessel (a rectangular section pressure vessel) were calculated. The module vessel did a rectangular section from limitation of a high neutron flux domain. Also, we investigated damage of thermocouples under neutron irradiation, which was a temperature sensor of irradiation materials temperature control demanded high precision. Based on these results, drawings on the HTFM structure. (author)

  10. Modulational instability of ion-acoustic soliton in a multicomponent plasma

    International Nuclear Information System (INIS)

    Tsukabayashi, I.; Yagishita, T.; Nakamura, Y.

    1986-01-01

    An experiment has been performed in a multi-dipole double plasma device. The inner diameter is 80 cm and its total length is 150 cm. The chamber is evacuated down to 8x10/sup -7/ Torr. Argon and sulfur hexafluoride are introduced independently into the chamber under continuous pumping. The pressure of Ar is 2 x 10/sup -4/ Torr and the partial pressure of SF/sub 6/ is changed 0 to 3 x 10/sup -8/ Torr. The plasma includes several species of positive and negative ions, SF/sub 6//sup -/. However, since ions of lighter mass dominate the ion-acoustic wave, the plasma is considered to be effectively composed of AR/sup +/, F/sup -/ and electrons. Initial modulated sinusoidal signals, the absolute amplitude 1.5 to 0.1 V, the percentage modulation 0 to 100%, the duration of the train 200μsec, the carrier frequency f/sub o/ = w/2π = 200 to 300 kHz and the modulation frequency Ω/2π=15 to 20 kHz, are applied to the driver plasma. The detected signals increase the percentage modulation with the distance from the separation grid, and the growth rate is proportional to the amplitude of applied signal. The measurement of the power spectra show that the frequency of the carrier wave shifts to the lower side-bands (f/sub o/ -Ω/2π and f/sub o/ -2Ω/2π) as development of the amplitude modulation instability. These results can be explained by the analysis of the N-S equation

  11. 3D pressure field in lipid membranes and membrane-protein complexes

    DEFF Research Database (Denmark)

    Ollila, O H Samuli; Risselada, H Jelger; Louhivuori, Martti

    2009-01-01

    We calculate full 3D pressure fields for inhomogeneous nanoscale systems using molecular dynamics simulation data. The fields represent systems with increasing level of complexity, ranging from semivesicles and vesicles to membranes characterized by coexistence of two phases, including also...... a protein-membrane complex. We show that the 3D pressure field is distinctly different for curved and planar bilayers, the pressure field depends strongly on the phase of the membrane, and that an integral protein modulates the tension and elastic properties of the membrane....

  12. An integrated CAD/CAM system for CNG pressure vessel manufactured by deep drawing and ironing operation

    Energy Technology Data Exchange (ETDEWEB)

    Park, Joon Hong; Kim, Chul; Choi, Jae Chan [Pusan National Univ., Pusan (Korea, Republic of)

    2004-06-01

    The fiber reinforced composite material is widely used in the multi-industrial field because of their high specific modulus and specific strength. It has two main merits which are to cut down energy by reducing weight and to prevent explosive damage proceeding to the sudden bursting which is generated by the pressure leakage condition. Therefore, pressure vessels using this composite material can be applied in the field such as defence industry and aerospace industry. In this paper, for nonlinear finite element analysis of E-glass/epoxy filament winding of composite vessel subjected to internal pressure, the standard interpretation model is developed by using the ANSYS with AutoLISP and ANSYS APDL languages, general commercial software, which is verified as useful characteristic of the solution. Among the modules of the system, both the process planning module for carrying out the process planning of filament wound composite pressure vessel and the autofrettage process module for obtaining higher residual stress will minimize trial and error and reduce the period for developing new products. The system can serve as a valuable system for experts and as a dependable training aid for beginners.

  13. An integrated CAD/CAM system for CNG pressure vessel manufactured by deep drawing and ironing operation

    International Nuclear Information System (INIS)

    Park, Joon Hong; Kim, Chul; Choi, Jae Chan

    2004-01-01

    The fiber reinforced composite material is widely used in the multi-industrial field because of their high specific modulus and specific strength. It has two main merits which are to cut down energy by reducing weight and to prevent explosive damage proceeding to the sudden bursting which is generated by the pressure leakage condition. Therefore, pressure vessels using this composite material can be applied in the field such as defence industry and aerospace industry. In this paper, for nonlinear finite element analysis of E-glass/epoxy filament winding of composite vessel subjected to internal pressure, the standard interpretation model is developed by using the ANSYS with AutoLISP and ANSYS APDL languages, general commercial software, which is verified as useful characteristic of the solution. Among the modules of the system, both the process planning module for carrying out the process planning of filament wound composite pressure vessel and the autofrettage process module for obtaining higher residual stress will minimize trial and error and reduce the period for developing new products. The system can serve as a valuable system for experts and as a dependable training aid for beginners

  14. Pressure Drop Versus Flow Rate Analysis of the Limited Streamer Tube Gas System of the BaBar Muon Detector Upgrade

    International Nuclear Information System (INIS)

    Yi, M.

    2004-01-01

    It has been proposed that Limited Streamer Tubes (LST) be used in the current upgrade of the muon detector in the BaBar detector. An LST consists of a thin silver plated wire centered in a graphite-coated cell. One standard LST tube consists of eight such cells, and two or three such tubes form an LST module. Under operation, the cells are filled with a gas mixture of CO 2 , argon and isobutane. During normal operation of the detector, the gas will be flushed out of the system at a constant low rate of one volume change per day. During times such as installation, however, it is often desired to flush and change the LST gas volumes very rapidly, leading to higher than normal pressure which may damage the modules. This project studied this pressure as a function of flow rate and the number of modules that are put in series in search of the maximal safe flow rate at which to flush the modules. Measurements of pressure drop versus flow rate were taken using a flow meter and a pressure transducer on configurations of one to five modules put in series. Minimal Poly-Flo tubing was used for all connections between test equipment and modules. They contributed less than 25% to all measurements. A ratio of 0.00022 ± 0.00001 mmHg per Standard Cubic Centimeter per Minute (SCCM) per module was found, which was a slight overestimate since it included the contributions from the tubing connections. However, for the purpose of finding a flow rate at which the modules can be safely flushed, this overestimate acts as a safety cushion. For a standard module with a volume of 16 liters and a known safe overpressure of 2 inches of water, the ratio translates into a flow rate of 17000 ± 1000SCCM and a time requirement of 56 ± 5 seconds to flush an entire module

  15. The calcium-sensing receptor and calcimimetics in blood pressure modulation

    DEFF Research Database (Denmark)

    Smajilovic, Sanela; Yano, Shozo; Jabbari, Reza

    2011-01-01

    R (calcimimetics) are the first drugs in their class to become available for clinical use and have been shown to successfully treat certain forms of primary and secondary hyperparathyroidism. In addition, several studies suggest beneficial effects of calcimimetics on cardiovascular risk factors associated....... This review will summarize the current knowledge on the possible functions of the CaR and calcimimetics on blood pressure regulation....

  16. High-pressure microscopy for tracking dynamic properties of molecular machines.

    Science.gov (United States)

    Nishiyama, Masayoshi

    2017-12-01

    High-pressure microscopy is one of the powerful techniques to visualize the effects of hydrostatic pressures on research targets. It could be used for monitoring the pressure-induced changes in the structure and function of molecular machines in vitro and in vivo. This review focuses on the dynamic properties of the assemblies and machines, analyzed by means of high-pressure microscopy measurement. We developed a high-pressure microscope that is optimized both for the best image formation and for the stability to hydrostatic pressure up to 150 MPa. Application of pressure could change polymerization and depolymerization processes of the microtubule cytoskeleton, suggesting a modulation of the intermolecular interaction between tubulin molecules. A novel motility assay demonstrated that high hydrostatic pressure induces counterclockwise (CCW) to clockwise (CW) reversals of the Escherichia coli flagellar motor. The present techniques could be extended to study how molecular machines in complicated systems respond to mechanical stimuli. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. An ultralow power wireless intraocular pressure monitoring system

    International Nuclear Information System (INIS)

    Liu Demeng; Mei Niansong; Zhang Zhaofeng

    2014-01-01

    This paper describes an ultralow power wireless intraocular pressure (IOP) monitoring system that is dedicated to sensing and transferring intraocular pressure of glaucoma patients. Our system is comprised of a capacitive pressure sensor, an application-specific integrated circuit, which is designed on the SMIC 180 nm process, and a dipole antenna. The system is wirelessly powered and demonstrates a power consumption of 7.56 μW at 1.24 V during continuous monitoring, a significant reduction in active power dissipation compared to existing work. The input RF sensitivity is −13 dBm. A significant reduction in input RF sensitivity results from the reduction of mismatch time of the ASK modulation caused by FM0 encoding. The system exhibits an average error of ± 1.5 mmHg in measured pressure. Finally, a complete IOP system is demonstrated in the real biological environment, showing a successful reading of the pressure of an eye. (semiconductor integrated circuits)

  18. Chromatic Modulator for a High-Resolution CCD or APS

    Science.gov (United States)

    Hartley, Frank; Hull, Anthony

    2008-01-01

    A chromatic modulator has been proposed to enable the separate detection of the red, green, and blue (RGB) color components of the same scene by a single charge-coupled device (CCD), active-pixel sensor (APS), or similar electronic image detector. Traditionally, the RGB color-separation problem in an electronic camera has been solved by use of either (1) fixed color filters over three separate image detectors; (2) a filter wheel that repeatedly imposes a red, then a green, then a blue filter over a single image detector; or (3) different fixed color filters over adjacent pixels. The use of separate image detectors necessitates precise registration of the detectors and the use of complicated optics; filter wheels are expensive and add considerably to the bulk of the camera; and fixed pixelated color filters reduce spatial resolution and introduce color-aliasing effects. The proposed chromatic modulator would not exhibit any of these shortcomings. The proposed chromatic modulator would be an electromechanical device fabricated by micromachining. It would include a filter having a spatially periodic pattern of RGB strips at a pitch equal to that of the pixels of the image detector. The filter would be placed in front of the image detector, supported at its periphery by a spring suspension and electrostatic comb drive. The spring suspension would bias the filter toward a middle position in which each filter strip would be registered with a row of pixels of the image detector. Hard stops would limit the excursion of the spring suspension to precisely one pixel row above and one pixel row below the middle position. In operation, the electrostatic comb drive would be actuated to repeatedly snap the filter to the upper extreme, middle, and lower extreme positions. This action would repeatedly place a succession of the differently colored filter strips in front of each pixel of the image detector. To simplify the processing, it would be desirable to encode information on

  19. Inclusion of pressure and flow in the KITES MHD equilibrium code

    International Nuclear Information System (INIS)

    Raburn, Daniel; Fukuyama, Atsushi

    2013-01-01

    One of the simplest self-consistent models of a plasma is single-fluid magnetohydrodynamic (MHD) equilibrium with no bulk fluid flow under axisymmetry. However, both fluid flow and non-axisymmetric effects can significantly impact plasma equilibrium and confinement properties: in particular, fluid flow can produce profile pedestals, and non-axisymmetric effects can produce islands and stochastic regions. There exist a number of computational codes which are capable of calculating equilibria with arbitrary flow or with non-axisymmetric effects. Previously, a concept for a code to calculate MHD equilibria with flow in non-axisymmetric systems was presented, called the KITES (Kyoto ITerative Equilibrium Solver) code. Since then, many of the computational modules for the KITES code have been completed, and the work-in-progress KITES code has been used to calculate non-axisymmetric force-free equilibria. Additional computational modules are required to allow the KITES code to calculate equilibria with pressure and flow. Here, the authors report on the approaches used in developing these modules and provide a sample calculation with pressure. (author)

  20. Noninvasive blood pressure measurement scheme based on optical fiber sensor

    Science.gov (United States)

    Liu, Xianxuan; Yuan, Xueguang; Zhang, Yangan

    2016-10-01

    Optical fiber sensing has many advantages, such as volume small, light quality, low loss, strong in anti-jamming. Since the invention of the optical fiber sensing technology in 1977, optical fiber sensing technology has been applied in the military, national defense, aerospace, industrial, medical and other fields in recent years, and made a great contribution to parameter measurement in the environment under the limited condition .With the rapid development of computer, network system, the intelligent optical fiber sensing technology, the sensor technology, the combination of computer and communication technology , the detection, diagnosis and analysis can be automatically and efficiently completed. In this work, we proposed a noninvasive blood pressure detection and analysis scheme which uses optical fiber sensor. Optical fiber sensing system mainly includes the light source, optical fiber, optical detector, optical modulator, the signal processing module and so on. wavelength optical signals were led into the optical fiber sensor and the signals reflected by the human body surface were detected. By comparing actual testing data with the data got by traditional way to measure the blood pressure we can establish models for predicting the blood pressure and achieve noninvasive blood pressure measurement by using spectrum analysis technology. Blood pressure measurement method based on optical fiber sensing system is faster and more convenient than traditional way, and it can get accurate analysis results in a shorter period of time than before, so it can efficiently reduce the time cost and manpower cost.

  1. Bound on largest r ∼< 0.1 from sub-Planckian excursions of inflaton

    International Nuclear Information System (INIS)

    Chatterjee, Arindam; Mazumdar, Anupam

    2015-01-01

    In this paper we will discuss the range of large tensor to scalar ratio, r, obtainable from a sub-Planckian excursion of a single, slow roll driven inflaton field. In order to obtain a large r for such a scenario one has to depart from a monotonic evolution of the slow roll parameters in such a way that one still satisfies all the current constraints of \\texttt(Planck), such as the scalar amplitude, the tilt in the scalar power spectrum, running and running of the tilt close to the pivot scale. Since the slow roll parameters evolve non-monotonically, we will also consider the evolution of the power spectrum on the smallest scales, i.e. at P s (k ∼ 10 16  Mpc −1 )∼< 10 −2 , to make sure that the amplitude does not become too large. All these constraints tend to keep the tensor to scalar ratio, r ∼< 0.1. We scan three different kinds of potential for supersymmetric flat directions and obtain the benchmark points which satisfy all the constraints. We also show that it is possible to go beyond r ∼> 0.1 provided we relax the upper bound on the power spectrum on the smallest scales

  2. An Excursion Set Model of the Cosmic Web: the Abundance of Sheets, Filaments And Halos

    Energy Technology Data Exchange (ETDEWEB)

    Shen, Jiajian; /Penn State U., Astron. Astrophys.; Abel, Tom; /KIPAC, Menlo Park; Mo, Houjun; /Massachusetts U., Amherst; Sheth, Ravi; /Pennsylvania U.

    2006-01-11

    We discuss an analytic approach for modeling structure formation in sheets, filaments and knots. This is accomplished by combining models of triaxial collapse with the excursion set approach: sheets are defined as objects which have collapsed along only one axis, filaments have collapsed along two axes, and halos are objects in which triaxial collapse is complete. In the simplest version of this approach, which we develop here, large scale structure shows a clear hierarchy of morphologies: the mass in large-scale sheets is partitioned up among lower mass filaments, which themselves are made-up of still lower mass halos. Our approach provides analytic estimates of the mass fraction in sheets, filaments and halos, and its evolution, for any background cosmological model and any initial fluctuation spectrum. In the currently popular {Lambda}CDM model, our analysis suggests that more than 99% of the mass in sheets, and 72% of the mass in filaments, is stored in objects more massive than 10{sup 10}M{sub {circle_dot}} at the present time. For halos, this number is only 46%. Our approach also provides analytic estimates of how halo abundances at any given time correlate with the morphology of the surrounding large-scale structure, and how halo evolution correlates with the morphology of large scale structure.

  3. LOFT fuel modules design, characterization, and fabrication program

    International Nuclear Information System (INIS)

    Russell, M.L.

    1977-06-01

    The loss-of-fluid test [LOFT) fuel modules have evolved from a comprehensive five-year design, characterization, and fabrication program which has resulted in the accomplishment of many technical activities of interest in pressurized water reactor fuel design development and safety research. Information is presented concerning: determination of fundamental high-temperature reactor material properties; design invention related to in-core instrumentation attachment; implementation of advanced and/or unique fuel bundle characterization techniques; implementation of improved fuel bundle fabrication techniques; and planning and execution of a multimillion dollar design, characterization, and fabrication program for pressurized water reactor fuel

  4. Load Dependency of Postural Control--Kinematic and Neuromuscular Changes in Response to over and under Load Conditions.

    Science.gov (United States)

    Ritzmann, Ramona; Freyler, Kathrin; Weltin, Elmar; Krause, Anne; Gollhofer, Albert

    2015-01-01

    Load variation is associated with changes in joint torque and compensatory reflex activation and thus, has a considerable impact on balance control. Previous studies dealing with over (OL) and under loading (UL) used water buoyancy or additional weight with the side effects of increased friction and inertia, resulting in substantially modified test paradigms. The purpose of this study was to identify gravity-induced load dependency of postural control in comparable experimental conditions and to determine the underlying neuromuscular mechanisms. Balance performance was recorded under normal loading (NL, 1 g), UL (0.16 g 0.38 g) and OL (1.8 g) in monopedal stance. Center of pressure (COP) displacement and frequency distribution (low 0.15-0.5 Hz (LF), medium 0.5-2 Hz (MF), high 2-6 Hz (HF)) as well as ankle, knee and hip joint kinematics were assessed. Soleus spinal excitability was determined by H/M-recruitment curves (H/M-ratios). Compared to NL, OL caused an increase in ankle joint excursion, COP HF domain and H/M-ratio. Concomitantly, hip joint excursion and COP LF decreased. Compared to NL, UL caused modulations in the opposite direction: UL decreased ankle joint excursions, COP HF and H/M-ratio. Collaterally, hip joint excursion and COP LF increased. COP was augmented both in UL and in OL compared to NL. Subjects achieved postural stability in OL and UL with greater difficulty compared to NL. Reduced postural control was accompanied by modified balance strategies and compensatory reflex activation. With increasing load, a shift from hip to ankle strategy was observed. Accompanying, COP frequency distribution shifted from LF to HF and spinal excitability was enhanced. It is suggested that in OL, augmented ankle joint torques are compensated by quick reflex-induced postural reactions in distal muscles. Contrarily, UL is associated with diminished joint torques and thus, postural equilibrium may be controlled by the proximal segments to adjust the center of

  5. Load Dependency of Postural Control - Kinematic and Neuromuscular Changes in Response to over and under Load Conditions

    Science.gov (United States)

    Ritzmann, Ramona; Freyler, Kathrin; Weltin, Elmar; Krause, Anne; Gollhofer, Albert

    2015-01-01

    Introduction Load variation is associated with changes in joint torque and compensatory reflex activation and thus, has a considerable impact on balance control. Previous studies dealing with over (OL) and under loading (UL) used water buoyancy or additional weight with the side effects of increased friction and inertia, resulting in substantially modified test paradigms. The purpose of this study was to identify gravity-induced load dependency of postural control in comparable experimental conditions and to determine the underlying neuromuscular mechanisms. Methods Balance performance was recorded under normal loading (NL, 1g), UL (0.16g; 0.38g) and OL (1.8g) in monopedal stance. Center of pressure (COP) displacement and frequency distribution (low 0.15-0.5Hz (LF), medium 0.5-2Hz (MF), high 2-6Hz (HF)) as well as ankle, knee and hip joint kinematics were assessed. Soleus spinal excitability was determined by H/M-recruitment curves (H/M-ratios). Results Compared to NL, OL caused an increase in ankle joint excursion, COP HF domain and H/M-ratio. Concomitantly, hip joint excursion and COP LF decreased. Compared to NL, UL caused modulations in the opposite direction: UL decreased ankle joint excursions, COP HF and H/M-ratio. Collaterally, hip joint excursion and COP LF increased. COP was augmented both in UL and in OL compared to NL. Conclusion Subjects achieved postural stability in OL and UL with greater difficulty compared to NL. Reduced postural control was accompanied by modified balance strategies and compensatory reflex activation. With increasing load, a shift from hip to ankle strategy was observed. Accompanying, COP frequency distribution shifted from LF to HF and spinal excitability was enhanced. It is suggested that in OL, augmented ankle joint torques are compensated by quick reflex-induced postural reactions in distal muscles. Contrarily, UL is associated with diminished joint torques and thus, postural equilibrium may be controlled by the proximal

  6. Load Dependency of Postural Control--Kinematic and Neuromuscular Changes in Response to over and under Load Conditions.

    Directory of Open Access Journals (Sweden)

    Ramona Ritzmann

    Full Text Available Load variation is associated with changes in joint torque and compensatory reflex activation and thus, has a considerable impact on balance control. Previous studies dealing with over (OL and under loading (UL used water buoyancy or additional weight with the side effects of increased friction and inertia, resulting in substantially modified test paradigms. The purpose of this study was to identify gravity-induced load dependency of postural control in comparable experimental conditions and to determine the underlying neuromuscular mechanisms.Balance performance was recorded under normal loading (NL, 1 g, UL (0.16 g 0.38 g and OL (1.8 g in monopedal stance. Center of pressure (COP displacement and frequency distribution (low 0.15-0.5 Hz (LF, medium 0.5-2 Hz (MF, high 2-6 Hz (HF as well as ankle, knee and hip joint kinematics were assessed. Soleus spinal excitability was determined by H/M-recruitment curves (H/M-ratios.Compared to NL, OL caused an increase in ankle joint excursion, COP HF domain and H/M-ratio. Concomitantly, hip joint excursion and COP LF decreased. Compared to NL, UL caused modulations in the opposite direction: UL decreased ankle joint excursions, COP HF and H/M-ratio. Collaterally, hip joint excursion and COP LF increased. COP was augmented both in UL and in OL compared to NL.Subjects achieved postural stability in OL and UL with greater difficulty compared to NL. Reduced postural control was accompanied by modified balance strategies and compensatory reflex activation. With increasing load, a shift from hip to ankle strategy was observed. Accompanying, COP frequency distribution shifted from LF to HF and spinal excitability was enhanced. It is suggested that in OL, augmented ankle joint torques are compensated by quick reflex-induced postural reactions in distal muscles. Contrarily, UL is associated with diminished joint torques and thus, postural equilibrium may be controlled by the proximal segments to adjust the center of

  7. Apparatus and method for non-contact, acoustic resonance determination of intraocular pressure

    Science.gov (United States)

    Sinha, D.N.; Wray, W.O.

    1994-12-27

    The apparatus and method for measuring intraocular pressure changes in an eye under investigation by detection of vibrational resonances therein. An ultrasonic transducer operating at its resonant frequency is amplitude modulated and swept over a range of audio frequencies in which human eyes will resonate. The output therefrom is focused onto the eye under investigation, and the resonant vibrations of the eye observed using a fiber-optic reflection vibration sensor. Since the resonant frequency of the eye is dependent on the pressure therein, changes in intraocular pressure may readily be determined after a baseline pressure is established. 3 figures.

  8. Fissile solution dynamics: Student research

    Energy Technology Data Exchange (ETDEWEB)

    Hetrick, D.L.

    1994-09-01

    There are two research projects in criticality safety at the University of Arizona: one in dynamic simulation of hypothetical criticality accidents in fissile solutions, and one in criticality benchmarks using transport theory. We have used the data from nuclear excursions in KEWB, CRAC, and SILENE to help in building models for solution excursions. An equation of state for liquids containing gas bubbles has been developed and coupled to point-reactor dynamics in an attempt to predict fission rate, yield, pressure, and kinetic energy. It appears that radiolytic gas is unimportant until after the first peak, but that it does strongly affect the shape of the subsequent power decrease and also the dynamic pressure.

  9. Experimental apparatus with full optical access for combustion experiments with laminar flames from a single circular nozzle at elevated pressures.

    Science.gov (United States)

    Joo, Peter H; Gao, Jinlong; Li, Zhongshan; Aldén, Marcus

    2015-03-01

    The design and features of a high pressure chamber and burner that is suitable for combustion experiments at elevated pressures are presented. The high pressure combustion apparatus utilizes a high pressure burner that is comprised of a chamber burner module and an easily accessible interchangeable burner module to add to its flexibility. The burner is well suited to study both premixed and non-premixed flames. The optical access to the chamber is provided through four viewports for direct visual observations and optical-based diagnostic techniques. Auxiliary features include numerous access ports and electrical connections and as a result, the combustion apparatus is also suitable to work with plasmas and liquid fuels. Images of methane flames at elevated pressures up to 25 atm and preliminary results of optical-based measurements demonstrate the suitability of the high pressure experimental apparatus for combustion experiments.

  10. Neutron-transparent first wall for module testing

    International Nuclear Information System (INIS)

    Fuller, G.M.; Cramer, B.A.; Haines, J.R.; Kirchner, J.; Engholm, B.A.; Seki, M.

    1983-01-01

    Major design goals for FED-R are the achievement of: (1) a high level of neutron exposure of the test modules and (2) a capability for rapid changeout of test modules. A major factor in rapid changeout is perceived to be the location of the vacuum boundary. In FED-R this boundary was set at the first wall so that module changeout did not require the plasma chamber to be brought up to atmosphere. Efforts to realize these goals in the design resulted in a neutronically thin outboard wall for the vacuum vessel constructed of 316 stainless steel (SS) with helium as a coolant. A normalized 14-MeV neutron transmission of 0.82 is expected, with an inlet pressure of 2 MPa and a pumping power requirement of 8.7 MW. Other options considered in the study were aluminum as a wall material and water and sodium potassium (NaK) as coolants

  11. Axial distribution of deformation in the cladding of pressurized water reactor fuel rods in a loss-of-coolant accident

    International Nuclear Information System (INIS)

    Rose, K.M.; Mann, C.A.; Hindle, E.D.

    1979-01-01

    In the event of a loss-of-coolant accident in a pressurized water reactor, the cladding of the fuel rods would undergo a temperature excursion while being subject to tensile hoop stress. The deformation behavior of 470-mm lengths of Zircaloy-4 fuel cladding has been studied experimentally; under a range of stress levels in the high-alpha range of zirconium (600 to 850 0 C), diametral strains of up to 70% were observed over the greater part of their length. A negative-feedback mechanism is suggested, based on the reduction of secondary creep rate following cooling by enhanced heat loss at swelling areas. An approximate analysis based on this mechanism was found to be in reasonable agreement with the experimental results. A computer modeling code is being developed to predict cladding deformation under realistic conditions

  12. Axial distribution of deformation in the cladding of pressurized water reactor fuel rods in a loss-of-coolant accident

    Energy Technology Data Exchange (ETDEWEB)

    Rose, K.M.; Mann, C.A.; Hindle, E.D.

    1979-12-01

    In the event of a loss-of-coolant accident in a pressurized water reactor, the cladding of the fuel rods would undergo a temperature excursion while being subject to tensile hoop stress. The deformation behavior of 470-mm lengths of Zircaloy-4 fuel cladding has been studied experimentally; under a range of stress levels in the high-alpha range of zirconium (600 to 850/sup 0/C), diametral strains of up to 70% were observed over the greater part of their length. A negative-feedback mechanism is suggested, based on the reduction of secondary creep rate following cooling by enhanced heat loss at swelling areas. An approximate analysis based on this mechanism was found to be in reasonable agreement with the experimental results. A computer modeling code is being developed to predict cladding deformation under realistic conditions.

  13. Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss.

    Science.gov (United States)

    Halassa, Michael M; Florian, Cedrick; Fellin, Tommaso; Munoz, James R; Lee, So-Young; Abel, Ted; Haydon, Philip G; Frank, Marcos G

    2009-01-29

    Astrocytes modulate neuronal activity by releasing chemical transmitters via a process termed gliotransmission. The role of this process in the control of behavior is unknown. Since one outcome of SNARE-dependent gliotransmission is the regulation of extracellular adenosine and because adenosine promotes sleep, we genetically inhibited the release of gliotransmitters and asked if astrocytes play an unsuspected role in sleep regulation. Inhibiting gliotransmission attenuated the accumulation of sleep pressure, assessed by measuring the slow wave activity of the EEG during NREM sleep, and prevented cognitive deficits associated with sleep loss. Since the sleep-suppressing effects of the A1 receptor antagonist CPT were prevented following inhibition of gliotransmission and because intracerebroventricular delivery of CPT to wild-type mice mimicked the transgenic phenotype, we conclude that astrocytes modulate the accumulation of sleep pressure and its cognitive consequences through a pathway involving A1 receptors.

  14. Cardiovascular responses to treadmill exercise in Nigerian ...

    African Journals Online (AJOL)

    2011-07-25

    Jul 25, 2011 ... The systolic blood pressure (SBP) and pressure rate product (PRP) ... Left ventricular hypertrophy (LVH) has been shown to be ... and functional evaluation of patients with cardiovascular ... excursion of the mitral valve leaflets. ..... blood flow reflecting diastolic behavior of the left ventricle in health and.

  15. Shear modulation experiments with ECCD on TCV

    International Nuclear Information System (INIS)

    Cirant, S.; Alberti, S.; Gandini, F.; Behn, R.; Goodman, T.P.; Nikkola, P.

    2006-01-01

    Anomalous electron transport is determined by turbulence, which in turn is affected by magnetic shear. A novel application of electron cyclotron current drive (ECCD), aiming at localized shear modulation, has been applied on the TCV tokamak for experiments on shear-dependent electron transport. Pairs of EC beams, absorbed at the same radius, with one oriented for co- and the other for counter-injection, are modulated out of phase in order to force a local modulation of current-density at constant input power. Off-axis deposition (ρ dep = 0.24) is performed to avoid the central region, where the low heat flux would make transport analysis difficult. In addition some sawteeth control is achieved in this way. A significant impact on local shear is achieved with I ECCD ∼ 0.1I OH , even when the modulation period is much shorter than the current diffusion time across the whole plasma radius. The main result is that although source (heat and particle) terms are constant, both electron density and temperature are modulated during alternated ECCD. Once equilibrium effects are taken into account for appropriate mapping of Thomson scattering measurements onto flux coordinates, modulation of T e and electron pressure, peaked on-axis, is confirmed at all radii internal to EC deposition. The best confinement occurs for co-injection, in which case a local decrease (∼55%) in the magnetic shear causes a decrease in the electron thermal diffusivity of a similar amount (∼65%)

  16. Application of EASY5 and MMS modules to BWR controller design

    International Nuclear Information System (INIS)

    Carmichael, L.A.; Rayes, L.; Yasutake, T.

    1987-01-01

    The application of EPRI's MMS Library and BCS' EASY5 simulation language to the design of a digital feedwater control system for the Monticello Boiling Water Nuclear Power Plant is discussed. In order to first design and then verify the digital feedwater controller algorithms, a digital simulation model of the Monticello plant was constructed using a combination of custom designed modules, existing MMS two-phase library modules, and standard modules available in the EASY5 library. Details of the process models, namely the BWR nuclear steam supply system, the steamline piping, and the feedwater piping are described in a companion paper. Details of the models for the existing BWR turbine pressure inlet pressure control and recirculation flow control system are described. These models are required to be operational during the transient analysis portion of the feedwater controller design verification, since they interact strongly with the reactor steam flow and water level. The design of the digital feedwater flow control loop is described. Its design is of particular interest because it requires consideration of control loop interaction and is, therefore, a simple example of multivariable non-interacting control design

  17. Module theory, extending modules and generalizations

    CERN Document Server

    Tercan, Adnan

    2016-01-01

    The main focus of this monograph is to offer a comprehensive presentation of known and new results on various generalizations of CS-modules and CS-rings. Extending (or CS) modules are generalizations of injective (and also semisimple or uniform) modules. While the theory of CS-modules is well documented in monographs and textbooks, results on generalized forms of the CS property as well as dual notions are far less present in the literature. With their work the authors provide a solid background to module theory, accessible to anyone familiar with basic abstract algebra. The focus of the book is on direct sums of CS-modules and classes of modules related to CS-modules, such as relative (injective) ejective modules, (quasi) continuous modules, and lifting modules. In particular, matrix CS-rings are studied and clear proofs of fundamental decomposition results on CS-modules over commutative domains are given, thus complementing existing monographs in this area. Open problems round out the work and establish the...

  18. Nuclear Engineering Computer Modules, Thermal-Hydraulics, TH-3: High Temperature Gas Cooled Reactor Thermal-Hydraulics.

    Science.gov (United States)

    Reihman, Thomas C.

    This learning module is concerned with the temperature field, the heat transfer rates, and the coolant pressure drop in typical high temperature gas-cooled reactor (HTGR) fuel assemblies. As in all of the modules of this series, emphasis is placed on developing the theory and demonstrating its use with a simplified model. The heart of the module…

  19. Gas separation performance of a hollow-filament type polyimide membrane module for a compact tritium removal system

    International Nuclear Information System (INIS)

    Hayashi, Takumi; Yamada, Masayuki; Suzuki, Takumi; Matsuda, Yuji; Okuno, Kenji

    1995-01-01

    A new tritium removal system using gas separation membranes has been studied to develop more compact and cost-effective system for a fusion reactor. To obtain necessary parameters, which are directly scalable to the ITER Atmospheric Detritiation System, the basic tritium recovery performance was investigated with a scaled polyimide membrane module (hollow-filament type : 10 m 3 /hr) loop. The result shows that the H 2 recovery ratio from N 2 or air was more than 99% or about 97%, respectively, at flow rate ratio of permeated/feed = 0.1, feed ampersand permeated side pressures = 2580 ampersand 80 torr, and module temp. = 293 K. Tritium (HT) recovery function was almost the same as H 2 recovery, even though the total hydrogen concentration was a few ppm in the feed of module. H 2 O recovery performance was better than hydrogen recovery. These recovery functions were improved effectively decreasing the pressure ratio of permeated/feed of module. 5 refs., 11 figs

  20. The Pacman Perforator-Based V-Y Advancement Flap for Reconstruction of Pressure Sores at Different Locations.

    Science.gov (United States)

    Bonomi, Stefano; Salval, André; Brenta, Federica; Rapisarda, Vincenzo; Settembrini, Fernanda

    2016-09-01

    Many procedures have been proposed for the treatment of pressure sores, and V-Y advancement flaps are widely used to repair a defect. Unfortunately, the degree of mobility of a V-Y advancement flap is dependent on the laxity of the underlying subcutaneous tissue. This is an important disadvantage of traditional V-Y advancement flap and limits its use.We used V-Y advancement flaps as perforator-based to overcome mobility restriction problem, with a further modification (Pacman-like shape) to improve the covering surface area of the flap. Between January 2012 and December 2014, the authors used 37 V-Y Pacman perforator-based flaps in 33 consecutive patients for coverage of defects located at sacral (n = 21), ischial (n = 13), trochanter (n = 1) regions. There were 27 male and 6 female patients with a mean age of 49.9 years (range, 15-74 years). All flaps survived completely (92.3%) except 3 in which one of them had undergone total necrosis due to hematoma and the other 2 had partial necrosis. No venous congestion was observed. The mean follow-up period was 14.9 months (range, 2-38 months). No flap surgery-related mortality or recurrence of pressure sores was noted. The V-Y Pacman perforator-based advancement flaps are safe and very effective for reconstruction of pressure sores at various regions. The advantage of our modification procedure include shorter operative time, lesser pedicle dissection, low donor site morbidity, good preservation of muscle, and offers remarkable excursion to the V-Y flap, which make the V-Y Pacman perforator-based flaps an excellent choice for large pressure sore coverage.

  1. Evaluative pressure overcomes perceptual load effects.

    Science.gov (United States)

    Normand, Alice; Autin, Frédérique; Croizet, Jean-Claude

    2015-06-01

    Perceptual load has been found to be a powerful bottom-up determinant of distractibility, with high perceptual load preventing distraction by any irrelevant information. However, when under evaluative pressure, individuals exert top-down attentional control by giving greater weight to task-relevant features, making them more distractible from task-relevant distractors. One study tested whether the top-down modulation of attention under evaluative pressure overcomes the beneficial bottom-up effect of high perceptual load on distraction. Using a response-competition task, we replicated previous findings that high levels of perceptual load suppress task-relevant distractor response interference, but only for participants in a control condition. Participants under evaluative pressure (i.e., who believed their intelligence was assessed) showed interference from task-relevant distractor at all levels of perceptual load. This research challenges the assumptions of the perceptual load theory and sheds light on a neglected determinant of distractibility: the self-relevance of the performance situation in which attentional control is solicited.

  2. Pregnancy-related changes in center of pressure during gait.

    Science.gov (United States)

    Bertuit, Jeanne; Leyh, Clara; Rooze, Marcel; Feipe, Véronique

    2017-01-01

    Physical and hormonal modifications occuring during the pregnancy, can lead to an increase in postural instability and to a higher risk of falls during gait. The first objective was to describe the center of pressure (COP) during late pregnancy at different gait velocity. Comparison of nulliparous women with postpartum women were conducted in order to investigate the effects of pregnancy. The second objective was to analyse COP variability between pregnant and non-pregnant women in order to investigate the effects of pregnancy on gait variability. Fifty-eight pregnant women in the last four months of pregnancy, nine postpartum women and twenty-three healthy non-pregnant women performed gait trials at three different speeds: preferred, slow and fast. In the last four months of pregnancy gait velocity decreased. During the pregnancy, gait velocity decreased by 22%, stopover time increased by 6-12%, COP excursion XY decreased by 5% and COP velocity decreased by 16% and 20% along the anteroposterior and transverse axes, respectively. After delivery, gait velocity increased by 3% but remained a lower compared to non-pregnant women (-12%). Intra-individual variability was greater for non-pregnant than pregnant women. COP parameters were influenced by pregnancy. This suggests that pregnant women establish very specific and individual strategies with the aim of maintaining stability during gait.

  3. Star Excursion Balance Test Performance Varies by Sport in Healthy Division I Collegiate Athletes.

    Science.gov (United States)

    Stiffler, Mikel R; Sanfilippo, Jennifer L; Brooks, M Alison; Heiderscheit, Bryan C

    2015-10-01

    Cross-sectional. To describe performance and asymmetry on the Star Excursion Balance Test (SEBT) by sex and sport, and to determine if differences exist within a collegiate athlete population. Performance on the SEBT may differ between sexes and levels of competition, though the results of previous studies have been inconsistent. Investigation of performance and asymmetry differences between sports is limited. Sex- and sport-specific reference values likely need to be determined to best assess SEBT performance. Performance on the SEBT was retrospectively reviewed in 393 healthy National Collegiate Athletic Association Division I collegiate athletes from 8 sports. Means, standard deviations, and 95% confidence intervals were calculated for all variables. Normalized reach distance (percent limb length) and asymmetry between limbs were compared for the anterior (ANT), posterolateral (PL), and posteromedial (PM) directions and for the composite (COMP) score using a 2-way analysis of variance (ANOVA) of sex by sport, and a 1-way ANOVA to separately compare sports within each sex. Average normalized reach distance ranged from 62% to 69%, 84% to 97%, and 99% to 113% in the ANT, PL, and PM directions, respectively, and from 82% to 92% in the COMP score. Normalized asymmetry ranged from 3% to 4%, 5% to 8%, and 5% to 6% in the ANT, PL, and PM directions, respectively. A significant sex-by-sport interaction (P = .039) was observed in the ANT direction, with a sex effect for soccer players (Psport.

  4. Modulation of invasive phenotype by interstitial pressure-driven convection in aggregates of human breast cancer cells.

    Directory of Open Access Journals (Sweden)

    Joe Tien

    Full Text Available This paper reports the effect of elevated pressure on the invasive phenotype of patterned three-dimensional (3D aggregates of MDA-MB-231 human breast cancer cells. We found that the directionality of the interstitial pressure profile altered the frequency of invasion by cells located at the surface of an aggregate. In particular, application of pressure at one end of an aggregate suppressed invasion at the opposite end. Experimental alteration of the configuration of cell aggregates and computational modeling of the resulting flow and solute concentration profiles revealed that elevated pressure inhibited invasion by altering the chemical composition of the interstitial fluid near the surface of the aggregate. Our data reveal a link between hydrostatic pressure, interstitial convection, and invasion.

  5. Vapor pressure lowering effects due to salinity and suction pressure in the depletion of vapor-dominated geothermal reservoirs

    Energy Technology Data Exchange (ETDEWEB)

    Battistelli, A. [Aquater S.p.A., Pisa (Italy); Calore, C. [Istituto Internazionale per le Ricerche Geotermiche-CNR, Pisa (Italy); Pruess, K. [Lawrence Berkeley Lab., Berkeley, CA (United States)

    1995-03-01

    The equation-of-state module able to handle saline brines with non-condensible gas, developed for the TOUGH2 simulator, has been improved to include vapor pressure lowering (VPL) due to suction pressure as represented by Kelvin`s equation. In this equation the effects of salt are considered whereas those of non-condensible gas have currently been neglected. Numerical simulations of fluid production from tight matrix blocks have been performed to evaluate the impact of VPL effects due to salinity and suction pressure on the depletion behaviour of vapor-dominated geothermal reservoirs. Previous studies performed neglected VPL due to suction pressure showed that for initial NaCl mass fractions above threshold values, {open_quotes}sealing{close_quotes} of the block occurs and large amounts of liquid fluid may not be recovered. On the other hand, below the threshold value the matrix block dries out due to fluid production. The inclusion of VPL due to suction pressure does not allow complete vaporization of the liquid phase. As a result, the threshold NaCl concentration above which sealing of the matrix block occurs is increased. Above the {open_quotes}critical{close_quotes} NaCl concentration, block depletion behaviour with and without the VPL due to suction pressure is almost identical, as liquid phase saturation remains high even after long production times. As the VPL due to suction pressure depends mainly on capillary pressure, the shape of capillary pressure functions used in numerical simulations is important in determining VPL effects on block depletion.

  6. Diffusive-to-ballistic transition of the modulated heat transport in a rarefied air chamber

    Science.gov (United States)

    Gomez-Heredia, C. L.; Macias, J.; Ordonez-Miranda, J.; Ares, O.; Alvarado-Gil, J. J.

    2017-01-01

    Modulated heat transfer in air subject to pressures from 760 Torr to 10-4 Torr is experimentally studied by means of a thermal-wave resonant cavity placed in a vacuum chamber. This is done through the analysis of the amplitude and phase delay of the photothermal signal as a function of the cavity length and pressure through of the Knudsen's number. The viscous, transitional, and free molecular regimes of heat transport are observed for pressures P>1.5 Torr, 25 mTorrheat transport.

  7. Aortic atherosclerosis is a key modulator of the prognostic value of postural blood pressure changes.

    Science.gov (United States)

    Courand, Pierre-Yves; Harbaoui, Brahim; Fay, Helène; Grandjean, Adrien; Milon, Hugues; Lantelme, Pierre

    2018-01-01

    Orthostatic blood pressure decrease or increase has been related to cardiovascular events in hypertensive patients. Large blood pressure changes after orthostatic stress are associated with autonomic and neurohormonal abnormalities; aortic atherosclerosis (ATS) may also play a role. We investigated the interaction of ATS on the prognostic value of postural blood pressure changes. In a cohort of 958 hypertensive patients with an aortography (mean ± standard deviation age 44 ± 11 years, 61% men, mean blood pressure 182/110 mmHg), blood pressure was measured after 10 min of rest in the supine position. Systolic blood pressure (SBP) was also measured in standing position, 1 min after the supine position. Blood pressure changes were calculated as supine SBP minus standing SBP and analyzed as absolute or arithmetic means. ATS was assessed using an aortography score. After 15 years of follow-up, 280 all-cause and 167 cardiovascular deaths occurred. In a multivariable Cox regression analysis adjusted for major cardiovascular risk factors and stratified according to ATS status, SBP changes were statistically associated with all-cause and cardiovascular mortality only in the presence of ATS: tertile 3 versus 1, 2.99 (1.37-6.49) and 4.08 (1.55-10.72) respectively, tertile 3 versus 2, 2.89 (1.29-6.46) and 4.82 (1.79-12.98), respectively (p for interaction: 0.003 for all-cause and 0.003 for cardiovascular mortality) for absolute changes. The hazard associated with the magnitude of SBP changes was more important than that associated with its direction. The prognostic significance of postural SBP changes is markedly influenced by ATS in hypertensive patients. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Design of a Continuous Blood Pressure Measurement System Based on Pulse Wave and ECG Signals.

    Science.gov (United States)

    Li, Jian-Qiang; Li, Rui; Chen, Zhuang-Zhuang; Deng, Gen-Qiang; Wang, Huihui; Mavromoustakis, Constandinos X; Song, Houbing; Ming, Zhong

    2018-01-01

    With increasingly fierce competition for jobs, the pressures on people have risen in recent years, leading to lifestyle and diet disorders that result in significantly higher risks of cardiovascular disease. Hypertension is one of the common chronic cardiovascular diseases; however, mainstream blood pressure measurement devices are relatively heavy. When multiple measurements are required, the user experience and the measurement results may be unsatisfactory. In this paper, we describe the design of a signal collection module that collects pulse waves and electrocardiograph (ECG) signals. The collected signals are input into a signal processing module to filter the noise and amplify the useful physiological signals. Then, we use a wavelet transform to eliminate baseline drift noise and detect the feature points of the pulse waves and ECG signals. We propose the concept of detecting the wave shape associated with an instance, an approach that minimizes the impact of atypical pulse waves on blood pressure measurements. Finally, we propose an improved method for measuring blood pressure based on pulse wave velocity that improves the accuracy of blood pressure measurements by 58%. Moreover, the results meet the american medical instrument promotion association standards, which demonstrate the feasibility of our measurement system.

  9. Banana regime pressure anisotropy in a bumpy cylinder magnetic field

    International Nuclear Information System (INIS)

    Garcia-Perciante, A.L.; Callen, J.D.; Shaing, K.C.; Hegna, C.C.

    2006-01-01

    The pressure anisotropy is calculated for a plasma in a bumpy cylindrical magnetic field in the low collisionality (banana) regime for small magnetic-field modulations (ε≡ΔB/2B parallel is then calculated and is shown to exceed the flux-surface-averaged parallel viscous force parallel > by a factor of O(1/ε). A high-frequency limit (ω>>ν) for the pressure anisotropy is also determined and the calculation is then extended to include the full frequency dependence by using an expansion in Cordey eigenfunctions

  10. Concurrent and discriminant validity of the Star Excursion Balance Test for military personnel with lateral ankle sprain.

    Science.gov (United States)

    Bastien, Maude; Moffet, Hélène; Bouyer, Laurent; Perron, Marc; Hébert, Luc J; Leblond, Jean

    2014-02-01

    The Star Excursion Balance Test (SEBT) has frequently been used to measure motor control and residual functional deficits at different stages of recovery from lateral ankle sprain (LAS) in various populations. However, the validity of the measure used to characterize performance--the maximal reach distance (MRD) measured by visual estimation--is still unknown. To evaluate the concurrent validity of the MRD in the SEBT estimated visually vs the MRD measured with a 3D motion-capture system and evaluate and compare the discriminant validity of 2 MRD-normalization methods (by height or by lower-limb length) in participants with or without LAS (n = 10 per group). There is a high concurrent validity and a good degree of accuracy between the visual estimation measurement and the MRD gold-standard measurement for both groups and under all conditions. The Cohen d ratios between groups and MANOVA products were higher when computed from MRD data normalized by height. The results support the concurrent validity of visual estimation of the MRD and the use of the SEBT to evaluate motor control. Moreover, normalization of MRD data by height appears to increase the discriminant validity of this test.

  11. Two-phase flow instabilities in a vertical annular channel

    Energy Technology Data Exchange (ETDEWEB)

    Babelli, I.; Nair, S.; Ishii, M. [Purdue Univ., West Lafayette, IN (United States)

    1995-09-01

    An experimental test facility was built to study two-phase flow instabilities in vertical annular channel with emphasis on downward flow under low pressure and low flow conditions. The specific geometry of the test section is similar to the fuel-target sub-channel of the Savannah River Site (SRS) Mark 22 fuel assembly. Critical Heat Flux (CHF) was observed following flow excursion and flow reversal in the test section. Density wave instability was not recorded in this series of experimental runs. The results of this experimental study show that flow excursion is the dominant instability mode under low flow, low pressure, and down flow conditions. The onset of instability data are plotted on the subcooling-Zuber (phase change) numbers stability plane.

  12. Geometry and scaling laws of excursion and iso-sets of enstrophy and dissipation in isotropic turbulence

    Science.gov (United States)

    Elsas, José Hugo; Szalay, Alexander S.; Meneveau, Charles

    2018-04-01

    Motivated by interest in the geometry of high intensity events of turbulent flows, we examine the spatial correlation functions of sets where turbulent events are particularly intense. These sets are defined using indicator functions on excursion and iso-value sets. Their geometric scaling properties are analysed by examining possible power-law decay of their radial correlation function. We apply the analysis to enstrophy, dissipation and velocity gradient invariants Q and R and their joint spatial distributions, using data from a direct numerical simulation of isotropic turbulence at Reλ ≈ 430. While no fractal scaling is found in the inertial range using box-counting in the finite Reynolds number flow considered here, power-law scaling in the inertial range is found in the radial correlation functions. Thus, a geometric characterisation in terms of these sets' correlation dimension is possible. Strong dependence on the enstrophy and dissipation threshold is found, consistent with multifractal behaviour. Nevertheless, the lack of scaling of the box-counting analysis precludes direct quantitative comparisons with earlier work based on multifractal formalism. Surprising trends, such as a lower correlation dimension for strong dissipation events compared to strong enstrophy events, are observed and interpreted in terms of spatial coherence of vortices in the flow.

  13. Boundary modulation effects on MHD instabilities in Heliotrons

    International Nuclear Information System (INIS)

    Nakajima, N.; Hudson, S.R.; Hegna, C.C.; Nakamura, Y.

    2005-01-01

    In three-dimensional configurations, the confinement region is surrounded by the stochastic magnetic field lines related to magnetic islands or separatrix, leading to the fact that the plasma-vacuum boundary is not so definite compared with tokamaks that the various modulations of the plasma-vacuum boundary will be induced around the stochastic region by a large Shafranov shift of the whole plasma, in especially high-β operations. To examine such the modulation effects of the plasma boundary on MHD instabilities, high-β plasmas allowing a large Shafranov shift are considered in the inward-shifted LHD configurations with the vacuum magnetic axis R ax of 3.6m, for which previous theoretical analyses indicate that pressure-driven modes are significantly more unstable compared with experimental observations. It is shown that the boundary modulation due to a free motion of the equilibrium plasma has not only significant stabilizing effects on ideal MHD instabilities, but also characteristics consistent to experimental observations. (author)

  14. Irreducible Specht modules are signed Young modules

    OpenAIRE

    Hemmer, David J.

    2005-01-01

    Recently Donkin defined signed Young modules as a simultaneous generalization of Young and twisted Young modules for the symmetric group. We show that in odd characteristic, if a Specht module $S^\\lambda$ is irreducible, then $S^\\lambda$ is a signed Young module. Thus the set of irreducible Specht modules coincides with the set of irreducible signed Young modules. This provides evidence for our conjecture that the signed Young modules are precisely the class of indecomposable self-dual module...

  15. Pressure Safety: Advanced Self-Study 30120

    Energy Technology Data Exchange (ETDEWEB)

    Glass, George [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-02-29

    Pressure Safety Advance Self-Study (Course 30120) consists of an introduction, five modules, and a quiz. To receive credit in UTrain for completing this course, you must score 80% or better on the 15-question quiz (check UTrain). Directions for initiating the quiz are appended to the end of this training manual. This course contains several links to LANL websites. UTrain might not support active links, so please copy links into the address line in your browser.

  16. Testing flat plate photovoltaic modules for terrestrial environment

    Science.gov (United States)

    Hoffman, A. R.; Arnett, J. C.; Ross, R. G., Jr.

    1979-01-01

    New qualification tests have been developed for flat plate photovoltaic modules. Temperature cycling, cyclic pressure load, and humidity exposure are especially useful for detecting design and fabrication deficiencies. There is positive correlation between many of the observed field effects, such as power loss, and qualification test induced degradation. The status of research efforts for the development of test methodology for field-related problems is reviewed.

  17. Effects of hormone therapy on blood pressure.

    Science.gov (United States)

    Issa, Zeinab; Seely, Ellen W; Rahme, Maya; El-Hajj Fuleihan, Ghada

    2015-04-01

    Although hormone therapy remains the most efficacious option for the management of vasomotor symptoms of menopause, its effects on blood pressure remain unclear. This review scrutinizes evidence of the mechanisms of action of hormone therapy on signaling pathways affecting blood pressure and evidence from clinical studies. Comprehensive Ovid MEDLINE searches were conducted for the terms "hypertension" and either of the following "hormone therapy and menopause" or "selective estrogen receptor modulator" from year 2000 to November 2013. In vitro and physiologic studies did not reveal a clear deleterious effect of hormone therapy on blood pressure. The effect of oral therapy was essentially neutral in large trials conducted in normotensive women with blood pressure as primary outcome. Results from all other trials had several limitations. Oral therapy had a neutral effect on blood pressure in hypertensive women. Transdermal estrogen and micronized progesterone had a beneficial effect on blood pressure in normotensive women and, at most, a neutral effect on hypertensive women. In general, tibolone and raloxifene had a neutral effect on blood pressure in both hypertensive and normotensive women. Large randomized trials are needed to assess the effect of oral hormone therapy on blood pressure as a primary outcome in hypertensive women and the effect of transdermal preparations on both normotensive and hypertensive women. Transdermal preparations would be the preferred mode of therapy for hypertensive women, in view of their favorable physiologic and clinical profiles. The decision regarding the use of hormone therapy should be individualized, and blood pressure should be monitored during the course of treatment.

  18. Modification of enzymes by use of high-pressure homogenization.

    Science.gov (United States)

    Dos Santos Aguilar, Jessika Gonçalves; Cristianini, Marcelo; Sato, Helia Harumi

    2018-07-01

    High-pressure is an emerging and relatively new technology that can modify various molecules. High-pressure homogenization (HPH) has been used in several studies on protein modification, especially in enzymes used or found in food, from animal, plant or microbial resources. According to the literature, the enzymatic activity can be modulated under pressure causing inactivation, stabilization or activation of the enzymes, which, depending on the point of view could be very useful. Homogenization can generate changes in the structure of the enzyme modifying various chemical bonds (mainly weak bonds) causing different denaturation levels and, consequently, affecting the catalytic activity. This review aims to describe the various alterations due to HPH treatment in enzymes, to show the influence of high-pressure on proteins and to report the HPH effects on the enzymatic activity of different enzymes employed in the food industry and research. Copyright © 2018 Elsevier Ltd. All rights reserved.

  19. Fluid Properties Measurements Using Wavelength Modulation Spectroscopy with First Harmonic Detection

    Science.gov (United States)

    Chen, Shin-Juh (Inventor); Silver, Joel A. (Inventor)

    2014-01-01

    An apparatus and method for monitoring gas velocity, temperature, and pressure in combustion systems and flow devices, in particular at inlets and isolators of scramjet engines. The invention employs wavelength modulation spectroscopy with first harmonic detection and without the need to scan the full absorption spectra.

  20. Spatially digitized tactile pressure sensors with tunable sensitivity and sensing range.

    Science.gov (United States)

    Choi, Eunsuk; Sul, Onejae; Hwang, Soonhyung; Cho, Joonhyung; Chun, Hyunsuk; Kim, Hongjun; Lee, Seung-Beck

    2014-10-24

    When developing an electronic skin with touch sensation, an array of tactile pressure sensors with various ranges of pressure detection need to be integrated. This requires low noise, highly reliable sensors with tunable sensing characteristics. We demonstrate the operation of tactile pressure sensors that utilize the spatial distribution of contact electrodes to detect various ranges of tactile pressures. The device consists of a suspended elastomer diaphragm, with a carbon nanotube thin-film on the bottom, which makes contact with the electrodes on the substrate with applied pressure. The electrodes separated by set distances become connected in sequence with tactile pressure, enabling consecutive electrodes to produce a signal. Thus, the pressure is detected not by how much of a signal is produced but by which of the electrodes is registering an output. By modulating the diaphragm diameter, and suspension height, it was possible to tune the pressure sensitivity and sensing range. Also, adding a fingerprint ridge structure enabled the sensor to detect the periodicity of sub-millimeter grating patterns on a silicon wafer.

  1. Central venous pressure and mean circulatory filling pressure in the dogfish Squalus acanthias: adrenergic control and role of the pericardium.

    Science.gov (United States)

    Sandblom, Erik; Axelsson, Michael; Farrell, Anthony P

    2006-11-01

    Subambient central venous pressure (Pven) and modulation of venous return through cardiac suction (vis a fronte) characterizes the venous circulation in sharks. Venous capacitance was estimated in the dogfish Squalus acanthias by measuring the mean circulatory filling pressure (MCFP) during transient occlusion of cardiac outflow. We tested the hypothesis that venous return and cardiac preload can be altered additionally through adrenergic changes of venous capacitance. The experiments involved the surgical opening of the pericardium to place a perivascular occluder around the conus arteriosus. Another control group was identically instrumented, but lacked the occluder, and was subjected to the same pharmacological protocol to evaluate how pericardioectomy affected cardiovascular status. Routine Pven was negative (-0.08+/-0.02 kPa) in control fish but positive (0.09+/-0.01 kPa) in the pericardioectomized group. Injections of 5 microg/kg body mass (Mb) of epinephrine and phenylephrine (100 microg/kg Mb) increased Pven and MCFP, whereas isoproterenol (1 microg/kg Mb) decreased both variables. Thus, constriction and relaxation of the venous vasculature were mediated through the respective stimulation of alpha- and beta-adrenergic receptors. Alpha-adrenergic blockade with prazosin (1 mg/kg Mb) attenuated the responses to phenylephrine and decreased resting Pven in pericardioectomized animals. Our results provide convincing evidence for adrenergic control of the venous vasculature in elasmobranchs, although the pericardium is clearly an important component in the modulation of venous function. Thus active changes in venous capacitance have previously been underestimated as an important means of modulating venous return and cardiac performance in this group.

  2. Signed Young Modules and Simple Specht Modules

    OpenAIRE

    Danz, Susanne; Lim, Kay Jin

    2015-01-01

    By a result of Hemmer, every simple Specht module of a finite symmetric group over a field of odd characteristic is a signed Young module. While Specht modules are parametrized by partitions, indecomposable signed Young modules are parametrized by certain pairs of partitions. The main result of this article establishes the signed Young module labels of simple Specht modules. Along the way we prove a number of results concerning indecomposable signed Young modules that are of independent inter...

  3. Earth's magnetic field is probably not reversing.

    Science.gov (United States)

    Brown, Maxwell; Korte, Monika; Holme, Richard; Wardinski, Ingo; Gunnarson, Sydney

    2018-04-30

    The geomagnetic field has been decaying at a rate of [Formula: see text]5% per century from at least 1840, with indirect observations suggesting a decay since 1600 or even earlier. This has led to the assertion that the geomagnetic field may be undergoing a reversal or an excursion. We have derived a model of the geomagnetic field spanning 30-50 ka, constructed to study the behavior of the two most recent excursions: the Laschamp and Mono Lake, centered at 41 and 34 ka, respectively. Here, we show that neither excursion demonstrates field evolution similar to current changes in the geomagnetic field. At earlier times, centered at 49 and 46 ka, the field is comparable to today's field, with an intensity structure similar to today's South Atlantic Anomaly (SAA); however, neither of these SAA-like fields develop into an excursion or reversal. This suggests that the current weakened field will also recover without an extreme event such as an excursion or reversal. The SAA-like field structure at 46 ka appears to be coeval with published increases in geomagnetically modulated beryllium and chlorine nuclide production, despite the global dipole field not weakening significantly in our model during this time. This agreement suggests a greater complexity in the relationship between cosmogenic nuclide production and the geomagnetic field than is commonly assumed.

  4. Evaluation of structural reliability for vacuum vessel under external pressure and electromagnetic force

    International Nuclear Information System (INIS)

    Minato, Akio

    1983-08-01

    Static and dynamic structural analyses of the vacuum vessel for a Swimming Pool Type Tokamak Reactor (SPTR) have been conducted under the external pressure (hydraulic and atmospheric pressure) during normal operation or the electromagnetic force due to plasma disruption. The reactor structural design is based on the concept that the adjacent modules of the vacuum vessel are not connected mechanically with bolts in the torus inboard region each other, so as to save the required space for inserting the remote handling machine for tightenning and untightenning bolts in the region and to simplify the repair and maintenance of the reactor. The structural analyses of the vacuum vessel have been carried out under the external pressure and the electromagnetic force and the structural reliability against the static and dynamic loads is estimated. The several configurations of the lip seal between the modules, which is required to make a plasma vacuum boundary, have been proposed and the structural strength under the forced displacements due to the deformation of the vacuum vessel is also estimated. (author)

  5. Improvement and evaluation of debris coolability analysis module in severe accident analysis code SAMPSON using LIVE experiment

    International Nuclear Information System (INIS)

    Wei, Hongyang; Erkan, Nejdet; Okamoto, Koji; Gaus-Liu, Xiaoyang; Miassoedov, Alexei

    2017-01-01

    Highlights: • Debris coolability analysis module in SAMPSON is validated. • Model for heat transfer between melt pool and pressure vessel wall is modified. • Modified debris coolability analysis module is found to give reasonable results. - Abstract: The purpose of this work is to validate the debris coolability analysis (DCA) module in the severe accident analysis code SAMPSON by simulating the first steady stage of the LIVE-L4 test. The DCA module is used for debris cooling in the lower plenum and for predicting the safety margin of present reactor vessels during a severe accident. In the DCA module, the spreading and cooling of molten debris, gap cooling, heating of a three-dimensional reactor vessel, and natural convection heat transfer are all considered. The LIVE experiment is designed to investigate the formation and stability of melt pools in a reactor pressure vessel (RPV). By comparing the simulation results and experimental data in terms of the average melt pool temperature and the heat flux along the vessel wall, a bug is found in the code and the model for the heat transfer between the melt pool and RPV wall is modified. Based on the Asfia–Dhir and Jahn–Reineke correlations, the modified version of the DCA module is found to give reasonable results for the average melt pool temperature, crust thickness in the steady state, and crust growth rate.

  6. Effect of DS Concentration on the PRO Performance Using a 5-Inch Scale Cellulose Triacetate-Based Hollow Fiber Membrane Module

    Directory of Open Access Journals (Sweden)

    Masahiro Yasukawa

    2018-05-01

    Full Text Available In this study, pressure-retarded osmosis (PRO performance of a 5-inch scale cellulose triacetate (CTA-based hollow fiber (HF membrane module was evaluated under a wide range of operating conditions (0.0–6.0 MPa of applied pressure, 0.5–2.0 L/min feed solution (FS inlet flow rate, 1.0–6.0 L/min DS inlet flow rate and 0.1–0.9 M draw solution (DS concentration by using a PRO/reverse osmosis (RO hybrid system. The subsequent RO system for DS regeneration enabled the evaluation of the steady-stated module performance. In the case of pilot-scale module operation, since the DS dilution and the feed solution (FS up-concentration had occurred and was not negligible, unlike the lab-scale experiment, PRO performance strongly depended on operating conditions such as inlet flow rates of both the DS and FS concentration. To compare the module performance with different configurations, we proposed a converted parameter in which a difference of the packing density between the spiral wound (SW and the HF module was fairly considered. In the case of HF configuration, because of high packing density, volumetric-based performance was higher than that of SW module, that is, the required number of the module would be less than that of SW module in a full-scale PRO plant.

  7. A new humane method of stunning broilers using low atmospheric pressure

    Science.gov (United States)

    This research project evaluated an alternative method of controlled atmosphere stunning of commercial broilers to induce anoxia utilizing a vacuum pump to reduce the oxygen tension, low atmospheric pressure stun (LAPS). A custom built 2 cage-module system (holding a total of 600 broilers each) with...

  8. Watermelon extract reduces blood pressure but does not change sympathovagal balance in prehypertensive and hypertensive subjects.

    Science.gov (United States)

    Massa, Nayara Moreira Lacerda; Silva, Alexandre Sérgio; Toscano, Luciana Tavares; Silva, Joanna D'arc Gomes Rodrigues; Persuhn, Darlene Camati; Gonçalves, Maria Da Conceição Rodrigues

    2016-08-01

    Previous studies have shown that watermelon extract reduces blood pressure through vasodilation. However, those studies have not verified whether sympathetic nervous activity is influenced by watermelon extract. This study aimed to evaluate the effect of supplementation with watermelon extract for 6 weeks on blood pressure and sympathovagal balance of prehypertensive and hypertensive individuals. Forty volunteers participated in a randomized, double-blind, experimental and placebo-controlled study. They consumed 6 g of watermelon extract daily (n = 20; age 48.7 ± 1.9 years, 10 men) or a placebo (n = 20; age 47.4 ± 1.2 years, 11 men) for 6 weeks. Blood pressure and cardiac autonomic modulation were measured. Watermelon extract promoted a significant reduction in systolic (137.8 ± 3.9 to 126.0 ± 4.0 mmHg, p watermelon extract reduces systolic and diastolic blood pressure in prehypertensive and hypertensive individuals, but does not alter the cardiac autonomic modulation of these individuals.

  9. Experimental investigation of MHD pressure losses in a mock-up of a liquid metal blanket

    Science.gov (United States)

    Mistrangelo, C.; Bühler, L.; Brinkmann, H.-J.

    2018-03-01

    Experiments have been performed to investigate the influence of a magnetic field on liquid metal flows in a scaled mock-up of a helium cooled lead lithium (HCLL) blanket. During the experiments pressure differences between points on the mock-up have been recorded for various values of flow rate and magnitude of the imposed magnetic field. The main contributions to the total pressure drop in the test-section have been identified as a function of characteristic flow parameters. For sufficiently strong magnetic fields the non-dimensional pressure losses are practically independent on the flow rate, namely inertia forces become negligible. Previous experiments on MHD flows in a simplified test-section for a HCLL blanket showed that the main contributions to the total pressure drop in a blanket module originate from the flow in the distributing and collecting manifolds. The new experiments confirm that the largest pressure drops occur along manifolds and near the first wall of the blanket module, where the liquid metal passes through small openings in the stiffening plates separating two breeder units. Moreover, the experimental data shows that with the present manifold design the flow does not distribute homogeneously among the 8 stacked boxes that form the breeding zone.

  10. Implementation of CFD module in the KORSAR thermal-hydraulic system code

    Energy Technology Data Exchange (ETDEWEB)

    Yudov, Yury V.; Danilov, Ilia G.; Chepilko, Stepan S. [Alexandrov Research Inst. of Technology (NITI), Sosnovy Bor (Russian Federation)

    2015-09-15

    The Russian KORSAR/GP (hereinafter KORSAR) computer code was developed by a joint team from Alexandrov NITI and OKB ''Gidropress'' for VVER safety analysis and certified by the Rostechnadzor of Russia in 2009. The code functionality is based on a 1D two-fluid model for calculation of two-phase flows. A 3D CFD module in the KORSAR computer code is being developed by Alexandrov NITI for representing 3D effects in the downcomer and lower plenum during asymmetrical loop operation. The CFD module uses Cartesian grid method with cut cell approach. The paper presents a numerical algorithm for coupling 1D and 3D thermal- hydraulic modules in the KORSAR code. The combined pressure field is calculated by the multigrid method. The performance efficiency of the algorithm for coupling 1D and 3D modules was demonstrated by solving the benchmark problem of mixing cold and hot flows in a T-junction.

  11. Design and analysis of a high pressure piezoelectric actuated microvalve

    NARCIS (Netherlands)

    Fazal, I.; Elwenspoek, Michael Curt

    2007-01-01

    A normally open piezoelectric actuated microvalve which modulates a gas flow is fabricated and tested. This work is based on the novel concept of combining micro-machining- and fine machining. The microvalve was tested for air flow. It is shown that a flow rate of 250 ml min-1 for a pressure

  12. Modulation of a compressional electromagnetic wave in a magnetized electron-positron quantum plasma.

    Science.gov (United States)

    Amin, M R

    2015-09-01

    Amplitude modulation of a compressional electromagnetic wave in a strongly magnetized electron-positron pair plasma is considered in the quantum magnetohydrodynamic regime. The important ingredients of this study are the inclusion of the external strong magnetic field, Fermi quantum degeneracy pressure, particle exchange potential, quantum diffraction effects via the Bohm potential, and dissipative effect due to collision of the charged carriers. A modified-nonlinear Schödinger equation is developed for the compressional magnetic field of the electromagnetic wave by employing the standard reductive perturbation technique. The linear and nonlinear dispersions of the electromagnetic wave are discussed in detail. For some parameter ranges, relevant to dense astrophysical objects such as the outer layers of white dwarfs, neutron stars, and magnetars, etc., it is found that the compressional electromagnetic wave is modulationally unstable and propagates as a dissipated electromagnetic wave. It is also found that the quantum effects due to the particle exchange potential and the Bohm potential are negligibly small in comparison to the effects of the Fermi quantum degeneracy pressure. The numerical results on the growth rate of the modulation instability is also presented.

  13. A study of mini-channel thermal module design for achieving high stability and high capability in electronic cooling

    International Nuclear Information System (INIS)

    Wang, Hsiang-Li; Wu, Huang-Ching; Kong Wang, S.; Hung, Tzu-Chen; Yang, Ruey-Jen

    2013-01-01

    In this study, pressure drop and heat transfer characteristics of multiple-mini-channel thermal modules were investigated quantitatively. The flow channels, which were mounted on one side of a copper test section, were designed in three types: (1) the first module consists of fourteen straight and parallel channels with a rectangular cross section of 1 mm × 3 mm, (2) the second module consists of fourteen gradually widening channels with a U-shaped cross section starting from an inlet section of 0.5 mm × 3 mm and increasing to an outlet section of 1 mm × 3 mm, and (3) the third module is similar to the second module except for the rectangular cross section. Visual observations and the measured boiling curves show that, in the straight channels, some bubbles cannot be flushed out of the channels fast enough, so they tend to flow back and accumulate at the entrance. This results in a rather dry channel condition for CHF (critical heat flux) to occur for the cases with low flow rates. For the widening channel modules, no occurrence of CHF was observed under an even lower operating pressure in an attempt to induce the incipient of CHF. Under a similar temperature rise at the channel exit, the maximum heat removal rate of the widening channels reaches 27 W/cm 2 which is at least twice as high as that of the straight channels. -- Highlights: ► Three mini-channel modules were designed, and experiments were carried out on pressure drop and heat transfer characteristics. ► Comparisons were made between one regular straight-channel module and two widening-channel modules with rectangular and U-shaped cross sections. ► It was found that the widening channels yield a stable two-phase heat transfer mode with no occurrence of CHF due to a better movement of the bubbles and the absence of backflow which causes accumulation of bubbles commonly occur at the entrance of the straight-shaped parallel channels. ► The maximum heat removal rate of the widening channels reaches

  14. Overview of results of the first phase of validation activities for the IFMIF High Flux Test Module

    International Nuclear Information System (INIS)

    Arbeiter, Frederik; Chen Yuming; Dolensky, Bernhard; Freund, Jana; Heupel, Tobias; Klein, Christine; Scheel, Nicola; Schlindwein, Georg

    2012-01-01

    Highlights: ► Validation of computational fluid dynamics (CFD) modeling approach for application in the IFMIF High Flux Test Module. ► Fabrication of prototypes of the irradiation capsules of the IFMIF High Flux Test Module. - Abstract: The international fusion materials irradiation facility (IFMIF) is projected to create an experimentally validated database of material properties relevant for fusion reactor designs. The IFMIF High Flux Test Module is the dedicated experiment to irradiate alloys in the temperature range 250–550 °C and up to 50 displacements per atom per irradiation cycle. The High Flux Test Module is developed to maximize the specimen payload in the restricted irradiation volume, and to minimize the temperature spread within each specimen bundle. Low pressure helium mini-channel cooling is used to offer a high integration density. Due to the demanding thermo-hydraulic and mechanical conditions, the engineering design process (involving numerical neutronic, thermo-hydraulic and mechanical analyses) is supported by extensive experimental validation activities. This paper reports on the prototype manufacturing, thermo-hydraulic modeling experiments and component tests, as well as on mechanical testing. For the testing of the 1:1 prototype of the High Flux Test Module, a dedicated test facility, the Helium Loop Karlsruhe-Low Pressure (HELOKA-LP) has been taken into service.

  15. A Harsh Environment Wireless Pressure Sensing Solution Utilizing High Temperature Electronics

    Science.gov (United States)

    Yang, Jie

    2013-01-01

    Pressure measurement under harsh environments, especially at high temperatures, is of great interest to many industries. The applicability of current pressure sensing technologies in extreme environments is limited by the embedded electronics which cannot survive beyond 300 °C ambient temperature as of today. In this paper, a pressure signal processing and wireless transmission module based on the cutting-edge Silicon Carbide (SiC) devices is designed and developed, for a commercial piezoresistive MEMS pressure sensor from Kulite Semiconductor Products, Inc. Equipped with this advanced high-temperature SiC electronics, not only the sensor head, but the entire pressure sensor suite is capable of operating at 450 °C. The addition of wireless functionality also makes the pressure sensor more flexible in harsh environments by eliminating the costly and fragile cable connections. The proposed approach was verified through prototype fabrication and high temperature bench testing from room temperature up to 450 °C. This novel high-temperature pressure sensing technology can be applied in real-time health monitoring of many systems involving harsh environments, such as military and commercial turbine engines. PMID:23447006

  16. Ion cyclotron wave excitation by double resonance coupling

    International Nuclear Information System (INIS)

    Fasoli, A.; Good, T.N.; Paris, P.J.; Skiff, F.; Tran, M.Q.

    1990-07-01

    A modulated high frequency wave is used to remotely excite low frequency oscillations in a linear, strongly magnetized plasma column. An electromagnetic wave is launched as an extraordinary mode across the plasma by an external waveguide in the Upper Hybrid frequency regime f=f UH =f ce =8 GHz, with P≤2 W. By frequency modulating (at f FM =1-60 kHz, with f ci ≅30 kHz) the pump wave, the resonant layer is swept radially across the profile and perpendicularly to the field lines at f=f FM . The resulting radial oscillation of the electron linear and non linear pressure can be considered to act as a source term for the ion wave. A localized virtual antenna is thereby created inside the plasma. Measurements of the ion dielectric response (interferograms and perturbed distribution functions) via laser induced fluorescence identify the two branches (forward, or ion-acoustic-like, and backward, or Bernstein, modes) of the electrostatic dispersion relation in the ion cyclotron frequency range. By changing the modulation bandwidth, and thus the spatial excursion of the oscillating resonant layer, a control on the perpendicular wavelength of the excited mode can be exerted. In particular, the possibility of selective excitation of the ion Bernstein wave is demonstrated experimentally. (author) 38 refs., 13 figs

  17. Constellation Architecture Team-Lunar Scenario 12.0 Habitation Overview

    Science.gov (United States)

    Kennedy, Kriss J.; Toups, Larry D.; Rudisill, Marianne

    2010-01-01

    This paper will describe an overview of the Constellation Architecture Team Lunar Scenario 12.0 (LS-12) surface habitation approach and concept performed during the study definition. The Lunar Scenario 12 architecture study focused on two primary habitation approaches: a horizontally-oriented habitation module (LS-12.0) and a vertically-oriented habitation module (LS-12.1). This paper will provide an overview of the 12.0 lunar surface campaign, the associated outpost architecture, habitation functionality, concept description, system integration strategy, mass and power resource estimates. The Scenario 12 architecture resulted from combining three previous scenario attributes from Scenario 4 "Optimized Exploration", Scenario 5 "Fission Surface Power System" and Scenario 8 "Initial Extensive Mobility" into Scenario 12 along with an added emphasis on defining the excursion ConOps while the crew is away from the outpost location. This paper will describe an overview of the CxAT-Lunar Scenario 12.0 habitation concepts and their functionality. The Crew Operations area includes basic crew accommodations such as sleeping, eating, hygiene and stowage. The EVA Operations area includes additional EVA capability beyond the suitlock function such as suit maintenance, spares stowage, and suit stowage. The Logistics Operations area includes the enhanced accommodations for 180 days such as enhanced life support systems hardware, consumable stowage, spares stowage, interconnection to the other habitation elements, a common interface mechanism for future growth, and mating to a pressurized rover or Pressurized Logistics Module (PLM). The Mission & Science Operations area includes enhanced outpost autonomy such as an IVA glove box, life support, medical operations, and exercise equipment.

  18. Laboratory test of a prototype heat storage module based on stable supercooling of sodium acetate trihydrate

    DEFF Research Database (Denmark)

    Dannemand, Mark; Kong, Weiqiang; Fan, Jianhua

    2015-01-01

    Laboratory test of a long term heat storage module utilizing the principle of stable supercooling of 199.5 kg of sodium acetate water mixture has been carried out. Avoiding phase separation of the incongruently melting salt hydrate by using the extra water principle increased the heat storage...... capacity. An external expansion vessel minimized the pressure built up in the module while heating and reduced the risk of instable supercooling. The module was stable supercooled at indoor ambient temperature for up to two months after which it was discharged. The energy discharged after activating...

  19. Sedentary Behavior and Light Physical Activity Are Associated with Brachial and Central Blood Pressure in Hypertensive Patients

    DEFF Research Database (Denmark)

    Gerage, A. M.; Benedetti, T. R. B.; Farah, B. Q.

    2015-01-01

    of this study was to investigate the association between the time spent in physical activities of different intensities and blood pressure levels, arterial stiffness and autonomic modulation in hypertensive patients. Methods In this cross-sectional study, 87 hypertensive patients (57.5 +/- 9.9 years of age) had...... are associated with lower blood pressure, without affecting arterial stiffness and cardiac autonomic modulation in hypertensive patients.......Background Physical activity is recommended as a part of a comprehensive lifestyle approach in the treatment of hypertension, but there is a lack of data about the relationship between different intensities of physical activity and cardiovascular parameters in hypertensive patients. The purpose...

  20. High RF power test of a CFC antenna module for lower hybrid current drive

    International Nuclear Information System (INIS)

    Maebara, S.; Seki, M.; Ikeda, Y.; Kiyono, K.; Suganuma, K.; Imai, T.; Goniche, M.; Bibet, Ph.; Brossaud, J.; Cano, V.; Kazarian-Vibert, F.; Froissard, P.; Rey, G.

    1998-01-01

    A mock-up of a 3.7 GHz Lower Hybrid Current Drive (LHCD) antenna module was fabricated from Carbon Fibre Composite (CFC) for the development of heat resistive low Z front facing the plasma. This 2 divided waveguide module is made from CFC plates and rods which are Cu-plated to reduce the RF losses. The withstand-voltage, the RF properties and the outgassing rates for long pulses and high RF power were tested at the Lower Hybrid test bed facility of Cadarache. A reference module made from Dispersion Strengthened Copper (DSC) was also fabricated. After the short pulse conditioning, long pulses with a power density ranging between 50 and 150 MW/m 2 were performed with no breakdowns on the CFC module. It was also checked that the highest power density, up to 150 MW/m 2 , could be transmitted when the waveguides are filled with H2 at a pressure of 5 x 10 -2 Pa. During a long pulse, the power reflection coefficient remains low in the 0.8-1.3 % range and no significant change in the reflection coefficient is measured after the thermal cycling provided by the long pulse operation. From thermocouple measurements, RF losses of the copper coated CFC and the DSC modules were compared. No significant differences were measured. From pressure measurements, it was found that the outgassing rate of Cu-plated CFC is about 6-7 times larger than of DSC at 300 deg.C. It is concluded that a CFC module is an attractive candidate for the hardening of the tip of the LHCD antenna. (author)

  1. Evaluation of the qualification of SPERT [Special Power Excursion Reactor Test] fuel for use in non-power reactors

    International Nuclear Information System (INIS)

    1987-08-01

    This report summarizes the US Nuclear Regulatory Commission staff's evaluation of the qualification of the stainless-steel-clad uranium/oxide (UO 2 ) fuel pins for use in non-power reactors. The fuel pins were originally procured in the 1960's as part of the Special Power Excursion Reactor Test (SPERT) program. Argonne National Laboratory (ANL) examined 600 SPERT fuel pins to verify that the pins were produced according to specification and to assess their present condition. The pins were visually inspected under 6X magnification and by X-radiographic, destructive, and metallographic examinations. Spectrographic and chemical analyses were performed on the UO 2 fuel. The results of the qualification examinations indicated that the SPERT fuel pins meet the requirements of Phillips Specification No. F-1-SPT and have suffered no physical damage since fabrication. Therefore, the qualification results give reasonable assurance that the SPERT fuel rods are suitable for use in non-power reactors provided that the effects of thin-wall defects in the region of the upper end cap and low-density fuel pellets are evaluated for the intended operating conditions. 1 ref., 4 figs., 11 tabs

  2. Environmental forcing of terrestrial carbon isotope excursion amplification across five Eocene hyperthermals

    Science.gov (United States)

    Bowen, G. J.; Abels, H.

    2015-12-01

    Abrupt changes in the isotope composition of exogenic carbon pools accompany many major episodes of global change in the geologic record. The global expression of this change in substrates that reflect multiple carbon pools provides important evidence that many events reflect persistent, global redistribution of carbon between reduced and oxidized stocks. As the diversity of records documenting any event grows, however, discrepancies in the expression of carbon isotope change among substrates are almost always revealed. These differences in magnitude, pace, and pattern of change can complicate interpretations of global carbon redistribution, but under ideal circumstances can also provide additional information on changes in specific environmental and biogeochemical systems that accompanied the global events. Here we evaluate possible environmental influences on new terrestrial records of the negative carbon isotope excursions (CIEs) associated with multiple hyperthermals of the Early Eocene, which show a common pattern of amplified carbon isotope change in terrestrial paleosol carbonate records relative to that recorded in marine substrates. Scaling relationships between climate and carbon-cycle proxies suggest that that the climatic (temperature) impact of each event scaled proportionally with the magnitude of its marine CIE, likely implying that all events involved release of reduced carbon with a similar isotopic composition. Amplification of the terrestrial CIEs, however, does not scale with event magnitude, being proportionally less for the first, largest event (the PETM). We conduct a sensitivity test of a coupled plant-soil carbon isotope model to identify conditions that could account for the observed CIE scaling. At least two possibilities consistent with independent lines of evidence emerge: first, varying effects of pCO2 change on photosynthetic carbon isotope discrimination under changing background pCO2, and second, contrasting changes in regional

  3. Lens intracellular hydrostatic pressure is generated by the circulation of sodium and modulated by gap junction coupling

    Science.gov (United States)

    Gao, Junyuan; Sun, Xiurong; Moore, Leon C.; White, Thomas W.; Brink, Peter R.

    2011-01-01

    We recently modeled fluid flow through gap junction channels coupling the pigmented and nonpigmented layers of the ciliary body. The model suggested the channels could transport the secretion of aqueous humor, but flow would be driven by hydrostatic pressure rather than osmosis. The pressure required to drive fluid through a single layer of gap junctions might be just a few mmHg and difficult to measure. In the lens, however, there is a circulation of Na+ that may be coupled to intracellular fluid flow. Based on this hypothesis, the fluid would cross hundreds of layers of gap junctions, and this might require a large hydrostatic gradient. Therefore, we measured hydrostatic pressure as a function of distance from the center of the lens using an intracellular microelectrode-based pressure-sensing system. In wild-type mouse lenses, intracellular pressure varied from ∼330 mmHg at the center to zero at the surface. We have several knockout/knock-in mouse models with differing levels of expression of gap junction channels coupling lens fiber cells. Intracellular hydrostatic pressure in lenses from these mouse models varied inversely with the number of channels. When the lens’ circulation of Na+ was either blocked or reduced, intracellular hydrostatic pressure in central fiber cells was either eliminated or reduced proportionally. These data are consistent with our hypotheses: fluid circulates through the lens; the intracellular leg of fluid circulation is through gap junction channels and is driven by hydrostatic pressure; and the fluid flow is generated by membrane transport of sodium. PMID:21624945

  4. Electrical stimulation of acupuncture points and blood pressure responses to postural changes: a pilot study.

    Science.gov (United States)

    Jones, Alice Y M; Kwan, Y L; Leung, Nathan T F; Yu, Rachel P W; Wu, Cindy M Y; Warburton, Darren E R

    2011-05-01

    Application of transcutaneous electrical stimulation over acupuncture points (Acu-TENS) facilitates heart rate recovery after exercise and restores hemodynamic stability after open heart surgery. The role of Acu-TENS on cardiovascular parameters in response to postural changes has not been reported. To investigate (1) the effect of Acu-TENS on blood pressure responses to -10º head-down postural change and (2) whether such effects were associated with modulation by the autonomic nervous system. Sixteen healthy volunteers, mean age 22.8 (SD, 3.1) years, were subjected to a -10º head-down tilt from the supine position on 3 separate occasions and received in random order the following 3 intervention protocols for 40 minutes before the postural change: Acu-TENS (over bilateral acupuncture points, PC6), sham-TENS (TENS applied to the skin over the patellae), and control (no electrical output from the TENS device applied at PC6). Mean arterial pressure, large artery elasticity index, cardiac output, and heart rate were recorded and compared at different stimulation protocols in the supine and -10º head-down tilt positions. Spectral analysis of heart rate variability was used to determine any modulation by the autonomic nervous system. Change in large artery elasticity index was observed only in the Acu-TENS group (P pressure appeared most stable during Acu-TENS. Autonomic nervous system modulation was not apparent with spectral analysis, irrespective of intervention. Sympathetic activity predominated in all positions. Acu-TENS seems to reduce blood pressure changes with -10º head-down tilt with concomitant changes in arterial vessel tone.

  5. Performance characterization of the FLEX low pressure helium facility for fusion technology experiments

    Energy Technology Data Exchange (ETDEWEB)

    Schlindwein, Georg, E-mail: schlindwein@kit.edu; Arbeiter, Frederik

    2014-10-15

    Highlights: • A gas loop for fusion R and D has been built and tested. • Facility requirements and their implementation are given. • The loop's functions and instrumentation are explained. • The loops performance has been characterized. - Abstract: FLEX (Fluid Dynamics Experimental Facility) is a multi-purpose small scale gas loop for research on fluid and thermodynamic investigations, especially heat transfer, flow field measurements and gas purification. Initially it was built for investigation on mini-channel gas-flow to design the HFTM module of IFMIF. Because of its versatility it offers a wide range of further applications, e.g. the research of pressure drops in mockups of breeder units of the helium cooled pebble bed (HCPB) test blanket module for ITER. The main parameters of the loop, which can be operated with inert gases and air are: (i) operation gas pressure 0.02–0.38 MPa abs., (ii) test section pressure head up to 0.12 MPa, (iii) tolerable gas temperature RT – 200 °C and (iv) mass flow rate 0.2–12 × 10{sup −3} kg/s for Helium. This paper gives a detailed view of the loop assembly with the components that generate and regulate the mass flow and loop pressure. The measurement instrumentation will be presented as well as a representative mass flow-pressure drop characteristic. Furthermore, the achievable gas purity will be discussed.

  6. Photovoltaic module and interlocked stack of photovoltaic modules

    Science.gov (United States)

    Wares, Brian S.

    2014-09-02

    One embodiment relates to an arrangement of photovoltaic modules configured for transportation. The arrangement includes a plurality of photovoltaic modules, each photovoltaic module including a frame. A plurality of individual male alignment features and a plurality of individual female alignment features are included on each frame. Adjacent photovoltaic modules are interlocked by multiple individual male alignment features on a first module of the adjacent photovoltaic modules fitting into and being surrounded by corresponding individual female alignment features on a second module of the adjacent photovoltaic modules. Other embodiments, features and aspects are also disclosed.

  7. Daily Administration of Short-Acting Liothyronine Is Associated with Significant Triiodothyronine Excursions and Fails to Alter Thyroid-Responsive Parameters.

    Science.gov (United States)

    Jonklaas, Jacqueline; Burman, Kenneth D

    2016-06-01

    TSH to the values seen during levothyroxine therapy. There were significant excursions in serum total and free T3 concentrations with once-daily therapy. Trials of combination therapy are likely to be associated with similar excursions, albeit of a lesser magnitude. Only the physical component score of the SF36 questionnaire and hyperthyroid symptoms changed significantly with conversion to liothyronine monotherapy. Sustained release preparations with stable serum T3 profiles may have entirely different outcomes.

  8. Large scale modulation of high frequency acoustic waves in periodic porous media.

    Science.gov (United States)

    Boutin, Claude; Rallu, Antoine; Hans, Stephane

    2012-12-01

    This paper deals with the description of the modulation at large scale of high frequency acoustic waves in gas saturated periodic porous media. High frequencies mean local dynamics at the pore scale and therefore absence of scale separation in the usual sense of homogenization. However, although the pressure is spatially varying in the pores (according to periodic eigenmodes), the mode amplitude can present a large scale modulation, thereby introducing another type of scale separation to which the asymptotic multi-scale procedure applies. The approach is first presented on a periodic network of inter-connected Helmholtz resonators. The equations governing the modulations carried by periodic eigenmodes, at frequencies close to their eigenfrequency, are derived. The number of cells on which the carrying periodic mode is defined is therefore a parameter of the modeling. In a second part, the asymptotic approach is developed for periodic porous media saturated by a perfect gas. Using the "multicells" periodic condition, one obtains the family of equations governing the amplitude modulation at large scale of high frequency waves. The significant difference between modulations of simple and multiple mode are evidenced and discussed. The features of the modulation (anisotropy, width of frequency band) are also analyzed.

  9. Polydyne displacement interferometer using frequency-modulated light

    Science.gov (United States)

    Arablu, Masoud; Smith, Stuart T.

    2018-05-01

    A radio-frequency Frequency-Modulated (FM) signal is used to diffract a He-Ne laser beam through an Acousto-Optic Modulator (AOM). Due to the modulation of the FM signal, the measured spectra of the diffracted beams comprise a series of phase-synchronized harmonics that have exact integer frequency separation. The first diffraction side-beam emerging from the AOM is selected by a slit to be used in a polydyne displacement interferometer in a Michelson interferometer topology. The displacement measurement is derived from the phase measurement of selected modulation harmonic pairs. Individual harmonic frequency amplitudes are measured using discrete Fourier transform applied to the signal from a single photodetector. Phase signals are derived from the changes in the amplitudes of different harmonic pairs (typically odd-even pairs) with the phase being extracted using a standard quadrature method. In this study, two different modulation frequencies of 5 and 10 kHz are used at different modulation depths. The measured displacements by different harmonic pairs are compared with a commercial heterodyne interferometer being used as a reference for these studies. Measurements obtained from five different harmonic pairs when the moving mirror of the interferometer is scanned over ranges up to 10 μm all show differences of less than 50 nm from the reference interferometer measurements. A drift test was also used to evaluate the differences between the polydyne interferometer and reference measurements that had different optical path lengths of approximately 25 mm and 50 mm, respectively. The drift test results indicate that about half of the differences can be attributed to temperature, pressure, and humidity variations. Other influences include Abbe and thermal expansion effects. Rough magnitude estimates using simple models for these two effects can account for remaining observed deviations.

  10. Development of additional module to neutron-physic and thermal-hydraulic computer codes for coolant acoustical characteristics calculation

    Energy Technology Data Exchange (ETDEWEB)

    Proskuryakov, K.N.; Bogomazov, D.N.; Poliakov, N. [Moscow Power Engineering Institute (Technical University), Moscow (Russian Federation)

    2007-07-01

    The new special module to neutron-physic and thermal-hydraulic computer codes for coolant acoustical characteristics calculation is worked out. The Russian computer code Rainbow has been selected for joint use with a developed module. This code system provides the possibility of EFOCP (Eigen Frequencies of Oscillations of the Coolant Pressure) calculations in any coolant acoustical elements of primary circuits of NPP. EFOCP values have been calculated for transient and for stationary operating. The calculated results for nominal operating were compared with results of measured EFOCP. For example, this comparison was provided for the system: 'pressurizer + surge line' of a WWER-1000 reactor. The calculated result 0.58 Hz practically coincides with the result of measurement (0.6 Hz). The EFOCP variations in transients are also shown. The presented results are intended to be useful for NPP vibration-acoustical certification. There are no serious difficulties for using this module with other computer codes.

  11. Development of additional module to neutron-physic and thermal-hydraulic computer codes for coolant acoustical characteristics calculation

    International Nuclear Information System (INIS)

    Proskuryakov, K.N.; Bogomazov, D.N.; Poliakov, N.

    2007-01-01

    The new special module to neutron-physic and thermal-hydraulic computer codes for coolant acoustical characteristics calculation is worked out. The Russian computer code Rainbow has been selected for joint use with a developed module. This code system provides the possibility of EFOCP (Eigen Frequencies of Oscillations of the Coolant Pressure) calculations in any coolant acoustical elements of primary circuits of NPP. EFOCP values have been calculated for transient and for stationary operating. The calculated results for nominal operating were compared with results of measured EFOCP. For example, this comparison was provided for the system: 'pressurizer + surge line' of a WWER-1000 reactor. The calculated result 0.58 Hz practically coincides with the result of measurement (0.6 Hz). The EFOCP variations in transients are also shown. The presented results are intended to be useful for NPP vibration-acoustical certification. There are no serious difficulties for using this module with other computer codes

  12. Pressure dependence of excited-state charge-carrier dynamics in organolead tribromide perovskites

    Science.gov (United States)

    Liu, X. C.; Han, J. H.; Zhao, H. F.; Yan, H. C.; Shi, Y.; Jin, M. X.; Liu, C. L.; Ding, D. J.

    2018-05-01

    Excited-state charge-carrier dynamics governs the performance of organometal trihalide perovskites (OTPs) and is strongly influenced by the crystal structure. Characterizing the excited-state charge-carrier dynamics in OTPs under high pressure is imperative for providing crucial insights into structure-property relations. Here, we conduct in situ high-pressure femtosecond transient absorption spectroscopy experiments to study the excited-state carrier dynamics of CH3NH3PbBr3 (MAPbBr3) under hydrostatic pressure. The results indicate that compression is an effective approach to modulate the carrier dynamics of MAPbBr3. Across each pressure-induced phase, carrier relaxation, phonon scattering, and Auger recombination present different pressure-dependent properties under compression. Responsiveness is attributed to the pressure-induced variation in the lattice structure, which also changes the electronic band structure. Specifically, simultaneous prolongation of carrier relaxation and Auger recombination is achieved in the ambient phase, which is very valuable for excess energy harvesting. Our discussion provides clues for optimizing the photovoltaic performance of OTPs.

  13. Weyl modules, demazure modules, KR-modules, crystals, fusion products and limit constructions

    OpenAIRE

    Fourier, G.; Littelmann, P.

    2007-01-01

    We study finite dimensional representations of current algebras, loop algebras and their quantized versions. For the current algebra of a simple Lie algebra of type {\\tt ADE}, we show that Kirillov-Reshetikhin modules and Weyl modules are in fact all Demazure modules. As a consequence one obtains an elementary proof of the dimension formula for Weyl modules for the current and the loop algebra. Further, we show that the crystals of the Weyl and the Demazure module are the same up to some addi...

  14. QUALITY OF Pinus elliottii PARTICLE BOARDS BONDED WITH POLYURETHANE ADHESIVE UNDER VARIOUS COMBINATIONS OF TEMPERATURE AND PRESSURE

    Directory of Open Access Journals (Sweden)

    Juarez Benigno Paes

    2011-09-01

    Full Text Available This work aimed to produce homogeneous layer particle boards with residues of Pinus elliottii wood adhered with polyurethane adhesive to castor oil plant base and to evaluate the effect of the combination of pressure and temperature in the quality of the particle boards produced. To do so, 12 particle boards were manufactured, subdivided into four treatments in function of the pressure (2.0; 3.0; 3.5; and 3.5 MPa and temperature (90; 90; 50; and 60 ºC. The particleboards were sectioned in test samples, and accomplished by physical-mechanical tests for the determination of density, swelling and absorption of water (0-2h; 2-24h; e 0-24h; rupture module and elasticity module in static bending, internal ligation and screw withdrawal. The particle boards pressed with pressure of 3.0 MPa and temperature of 90 ºC and that with pressure of 3.5 MPa and temperature of 60 ºC presented the best  results. The higher temperature of pressing was the predominant variable in the quality of those particle boards manufactured.

  15. A micro-fabricated hydrogen storage module with sub-atmospheric activation and durability in air exposure

    Energy Technology Data Exchange (ETDEWEB)

    Shan, Xi; Payer, Joe H. [Corrosion and Reliability Engineering, Department of Chemical and Biomolecular Engineering, University of Akron, 302 Buchtel Common, Akron, OH 44325 (United States); Wainright, Jesse S.; Dudik, Laurie [Department of Chemical Engineering, Case Western Reserve University, Cleveland, OH 44106 (United States)

    2011-01-15

    The objective of this work was to develop a hydrogen storage module for onboard electrical power sources suitable for use in micro-power systems and micro-electro-mechanical systems (MEMS). Hydrogen storage materials were developed as thin-film inks to be compatible with an integrated manufacturing process. Important design aspects were (a) ready activation at sub-atmospheric hydrogen pressure and room temperature and (b) durability, i.e. capable of hundreds of absorption/desorption cycles and resistance to deactivation on exposure to air. Inks with palladium-treated intermetallic hydrogen storage alloys were developed and are shown here to be compatible with a thin-film micro-fabrication process. These hydrogen storage modules absorb hydrogen readily at atmospheric pressure, and the absorption/desorption rates remained fast even after the ink was exposed to air for 47 weeks. (author)

  16. Superstability for Generalized Module Left Derivations and Generalized Module Derivations on a Banach Module (I

    Directory of Open Access Journals (Sweden)

    Rassias JM

    2009-01-01

    Full Text Available We discuss the superstability of generalized module left derivations and generalized module derivations on a Banach module. Let be a Banach algebra and a Banach -module, and . The mappings , and are defined and it is proved that if (resp., is dominated by then is a generalized (resp., linear module- left derivation and is a (resp., linear module- left derivation. It is also shown that if (resp., is dominated by then is a generalized (resp., linear module- derivation and is a (resp., linear module- derivation.

  17. Two-phase natural circulation experiments in a pressurized water loop with CANDU geometry

    Energy Technology Data Exchange (ETDEWEB)

    Ardron, K.H.; Krishnan, V.S.; McGee, G.R.; Anderson, J.W.D.; Hawley, E.H.

    1984-07-01

    A series of tests has been performed in the RD-12 loop, a 10-MPa pressurized-water loop containing two active boilers, two pumps, and two, or four, heated horizontal channels arranged in a symmetrical figure-of-eight configuration characteristic of the CANDU reactor primary heat-transport system. In the tests, single-phase natural circulation was established in the loop and void was introduced by controlled draining, with the surge tank (pressurizer) valved out of the system. Results indicate that a stable, two-phase, natural circulation flow can usually be established. However, as the void fraction in the loop is increased, large-amplitude flow oscillations can occur. The initial flow oscillations in the two halves of the loop are usually very nearly 180/sup 0/ out-of-phase. However, as the loop inventory is further decreased, an in-phase oscillation component is observed. In tests with two parallel, heated channels in each half-loop, oscillations associated with mass transfer between the channel pairs are also observed. Although flow oscillations can lead to intermittent dryout of the upper elements of the heater-rod assemblies in the horizontal channels, natural circulation cooling appears to be effective until about 50% of the loop inventory is drained; sustained flow stratification then occurs in the heated channels, leading to heater temperature excursions. The paper reviews the experimental results obtained and describes the evolution of natural circulation flow in particular cases as voidage is progressively increased. The stability behavior is discussed briefly with reference to a simple stability model.

  18. Involvement of α2-adrenoceptors in inhibitory and facilitatory pain modulation processes.

    Science.gov (United States)

    Vo, L; Drummond, P D

    2016-03-01

    In healthy humans, high-frequency electrical stimulation (HFS) of the forearm not only produces hyperalgesia at the site of stimulation but also reduces sensitivity to pressure-pain on the ipsilateral side of the forehead. In addition, HFS augments the ipsilateral trigeminal nociceptive blink reflex and intensifies the ipsilateral component of conditioned pain modulation. The aim of this study was to determine whether α2-adrenoceptors mediate these ipsilateral nociceptive influences. The α2-adrenoceptor antagonist yohimbine was administered to 22 participants in a double-blind, placebo-controlled crossover study. In each session, thermal and mechanical sensitivity in the forearms and forehead was assessed before and after HFS. In addition, the combined effect of HFS and yohimbine on the nociceptive blink reflex and on conditioned pain modulation was explored. In this paradigm, the conditioning stimulus was cold pain in the ipsilateral or contralateral temple, and the test stimulus was electrically evoked pain in the forearm. Blood pressure and electrodermal activity increased for several hours after yohimbine administration, consistent with blockade of central α2-adrenoceptors. Yohimbine not only augmented the nociceptive blink reflex ipsilateral to HFS but also intensified the inhibitory influence of ipsilateral temple cooling on electrically evoked pain at the HFS-treated site in the forearm. Yohimbine had no consistent effect on primary or secondary hyperalgesia in the forearm or on pressure-pain in the ipsilateral forehead. These findings imply involvement of α2-adrenoceptors both in ipsilateral antinociceptive and pronociceptive pain modulation processes. However, a mechanism not involving α2-adrenoceptors appears to mediate analgesia in the ipsilateral forehead after HFS. © 2015 European Pain Federation - EFIC®

  19. Post-test analysis of components from selenide isotope generator modules M-7, M-15, and M-18

    International Nuclear Information System (INIS)

    Wei, G.C.; Keiser, J.R.; Crouse, R.S.; Allen, M.D.; Schaffhauser, A.C.

    1979-05-01

    Several critical components removed from SIG (Selenide Isotope Generator) thermoelectric modules M-7, M-15C, M-15D, and M-18 were examined. These modules failed to show the predicted stability and conversion efficiency. Understanding the degradation and identifying means for preventing it necessitated detailed post-test examinations of key parts in the modules. Steel springs, which provided pressure for contacts at the hot and cold ends of P- or N-legs, relaxed more than expected. Beryllium oxide insulators had dark deposits that caused electrical shorts. The GdSe 1 49 N-leg exhibited cracking. The (Cu,Ag) 2 Se P-leg lost weight or sublimed excessively in module M-7 and more than expected in the other modules

  20. Deep breathing exercises with positive expiratory pressure in patients with multiple sclerosis - a randomized controlled trial.

    Science.gov (United States)

    Westerdahl, Elisabeth; Wittrin, Anna; Kånåhols, Margareta; Gunnarsson, Martin; Nilsagård, Ylva

    2016-11-01

    Breathing exercises with positive expiratory pressure are often recommended to patients with advanced neurological deficits, but the potential benefit in multiple sclerosis (MS) patients with mild and moderate symptoms has not yet been investigated in randomized controlled trials. To study the effects of 2 months of home-based breathing exercises for patients with mild to moderate MS on respiratory muscle strength, lung function, and subjective breathing and health status outcomes. Forty-eight patients with MS according to the revised McDonald criteria were enrolled in a randomized controlled trial. Patients performing breathing exercises (n = 23) were compared with a control group (n = 25) performing no breathing exercises. The breathing exercises were performed with a positive expiratory pressure device (10-15 cmH 2 O) and consisted of 30 slow deep breaths performed twice a day for 2 months. Respiratory muscle strength (maximal inspiratory and expiratory pressure at the mouth), spirometry, oxygenation, thoracic excursion, subjective perceptions of breathing and self-reported health status were evaluated before and after the intervention period. Following the intervention, there was a significant difference between the breathing group and the control group regarding the relative change in lung function, favoring the breathing group (vital capacity: P < 0.043; forced vital capacity: P < 0.025). There were no other significant differences between the groups. Breathing exercises may be beneficial in patients with mild to moderate stages of MS. However, the clinical significance needs to be clarified, and it remains to be seen whether a sustainable effect in delaying the development of respiratory dysfunction in MS can be obtained. © 2015 The Authors. The Clinical Respiratory Journal published by John Wiley & Sons Ltd.

  1. Clinical Potential of Hyperbaric Pressure-Treated Whey Protein

    Science.gov (United States)

    Piccolomini, André F.; Kubow, Stan; Lands, Larry C.

    2015-01-01

    Whey protein (WP) from cow’s milk is a rich source of essential and branched chain amino acids. Whey protein isolates (WPI) has been demonstrated to support muscle accretion, antioxidant activity, and immune modulation. However, whey is not readily digestible due to its tight conformational structure. Treatment of WPI with hyperbaric pressure results in protein unfolding. This enhances protein digestion, and results in an altered spectrum of released peptides, and greater release of essential and branched chain amino acids. Pressurized whey protein isolates (pWPI), through a series of cell culture, animal models and clinical studies, have been demonstrated to enhance muscle accretion, reduce inflammation, improve immunity, and decrease fatigue. It is also conceivable that pWPI would be more accessible to digestive enzymes, which would allow for a more rapid proteolysis of the proteins and an increased or altered release of small bioactive peptides. The altered profile of peptides released from WP digestion could thus play a role in the modulation of the immune response and tissue glutathione (GSH) concentrations. The research to date presents potentially interesting applications for the development of new functional foods based on hyperbaric treatment of WPI to produce products with more potent nutritional and nutraceutical properties. PMID:27417773

  2. On-line Analysis of Catalytic Reaction Products Using a High-Pressure Tandem Micro-reactor GC/MS.

    Science.gov (United States)

    Watanabe, Atsushi; Kim, Young-Min; Hosaka, Akihiko; Watanabe, Chuichi; Teramae, Norio; Ohtani, Hajime; Kim, Seungdo; Park, Young-Kwon; Wang, Kaige; Freeman, Robert R

    2017-01-01

    When a GC/MS system is coupled with a pressurized reactor, the separation efficiency and the retention time are directly affected by the reactor pressure. To keep the GC column flow rate constant irrespective of the reaction pressure, a restrictor capillary tube and an open split interface are attached between the GC injection port and the head of a GC separation column. The capability of the attached modules is demonstrated for the on-line GC/MS analysis of catalytic reaction products of a bio-oil model sample (guaiacol), produced under a pressure of 1 to 3 MPa.

  3. Effects of geometric modulation and surface potential heterogeneity on electrokinetic flow and solute transport in a microchannel

    Science.gov (United States)

    Bera, Subrata; Bhattacharyya, S.

    2018-04-01

    A numerical investigation is performed on the electroosmotic flow (EOF) in a surface-modulated microchannel to induce enhanced solute mixing. The channel wall is modulated by placing surface-mounted obstacles of trigonometric shape along which the surface potential is considered to be different from the surface potential of the homogeneous part of the wall. The characteristics of the electrokinetic flow are governed by the Laplace equation for the distribution of external electric potential; the Poisson equation for the distribution of induced electric potential; the Nernst-Planck equations for the distribution of ions; and the Navier-Stokes equations for fluid flow simultaneously. These nonlinear coupled set of governing equations are solved numerically by a control volume method over the staggered system. The influence of the geometric modulation of the surface, surface potential heterogeneity and the bulk ionic concentration on the EOF is analyzed. Vortical flow develops near a surface modulation, and it becomes stronger when the surface potential of the modulated region is in opposite sign to the surface potential of the homogeneous part of the channel walls. Vortical flow also depends on the Debye length when the Debye length is in the order of the channel height. Pressure drop along the channel length is higher for a ribbed wall channel compared to the grooved wall case. The pressure drop decreases with the increase in the amplitude for a grooved channel, but increases for a ribbed channel. The mixing index is quantified through the standard deviation of the solute distribution. Our results show that mixing index is higher for the ribbed channel compared to the grooved channel with heterogeneous surface potential. The increase in potential heterogeneity in the modulated region also increases the mixing index in both grooved and ribbed channels. However, the mixing performance, which is the ratio of the mixing index to pressure drop, reduces with the rise in

  4. Pressure pulsation in Kaplan turbines: Prototype-CFD comparison

    International Nuclear Information System (INIS)

    Rivetti, A; Lucino, C; Liscia, S; Muguerza, D; Avellan, F

    2012-01-01

    Pressure pulsation phenomena in a large Kaplan turbine are investigated by means of numerical simulations (CFD) and prototype measurements in order to study the dynamic behavior of flow due to the blade passage and its interaction with other components of the turbine. Numerical simulations are performed with the commercial software Ansys CFX code, solving the incompressible Unsteady Reynolds-Averaged-Navier Stokes equations under a finite volume scheme. The computational domain involves the entire machine at prototype scale. Special care is taken in the discretization of the wicket gate overhang and runner blade gap. Prototype measurements are performed using pressure transducers at different locations among the wicket gate outlet and the draft tube inlet. Then, CFD results are compared with temporary signals of prototype measurements at identical locations to validate the numerical model. A detailed analysis was focused on the tip gap flow and the pressure field at the discharge ring. From a rotating reference frame perspective, it is found that the mean pressure fluctuates accordingly the wicket gate passage. Moreover, in prototype measurements the pressure frequency that reveals the presence of modulated cavitation at the discharge ring is distinguished, as also verified from the shape of erosion patches in concordance with the number of wicket gates.

  5. Pressure pulsation in Kaplan turbines: Prototype-CFD comparison

    Science.gov (United States)

    Rivetti, A.; Lucino1, C.; Liscia, S.; Muguerza, D.; Avellan, F.

    2012-11-01

    Pressure pulsation phenomena in a large Kaplan turbine are investigated by means of numerical simulations (CFD) and prototype measurements in order to study the dynamic behavior of flow due to the blade passage and its interaction with other components of the turbine. Numerical simulations are performed with the commercial software Ansys CFX code, solving the incompressible Unsteady Reynolds-Averaged-Navier Stokes equations under a finite volume scheme. The computational domain involves the entire machine at prototype scale. Special care is taken in the discretization of the wicket gate overhang and runner blade gap. Prototype measurements are performed using pressure transducers at different locations among the wicket gate outlet and the draft tube inlet. Then, CFD results are compared with temporary signals of prototype measurements at identical locations to validate the numerical model. A detailed analysis was focused on the tip gap flow and the pressure field at the discharge ring. From a rotating reference frame perspective, it is found that the mean pressure fluctuates accordingly the wicket gate passage. Moreover, in prototype measurements the pressure frequency that reveals the presence of modulated cavitation at the discharge ring is distinguished, as also verified from the shape of erosion patches in concordance with the number of wicket gates.

  6. Developing eLearning for pressure ulcer prevention and management.

    Science.gov (United States)

    Cameron, Rosie; Rodgers, Angela; Welsh, Lynn; McGown, Katrina

    2014-08-12

    The impact of pressure ulcers is psychologically, physically and clinically challenging for both patients and NHS staff. NHS Greater Glasgow and Clyde (NHS GGC), in line with the Scottish Best Practice Statement for the Prevention and Management of Pressure Ulcers ( Quality Improvement Scotland, 2009 ), and the NHS Health Improvement Scotland (2011) Preventing Pressure Ulcers Change Package, launched an awareness campaign throughout the organisation in April 2012 and has more recently adopted a 'zero-tolerance' approach to pressure damage. The tissue viability service in NHS GGC recognised that in order to achieve this aim, education of front-line staff is essential. An educational framework for pressure ulcer prevention was developed for all levels of healthcare staff involved in the delivery of patient care. As a means to support the framework, an initiative to develop web-based eLearning modules has been taken forward. This has resulted in the creation of an accessible, cost-effective, stimulating, relevant, and evidence-based education programme designed around the educational needs of all healthcare staff. In conjunction with the organisation's 'top ten tools' for pressure ulcer prevention and management, the modular online education programme addresses the aims of quality improvement and zero tolerance by supporting the provision of safe and effective person-centered care.

  7. Subglottal pressure, tracheal airflow, and intrinsic laryngeal muscle activity during rat ultrasound vocalization

    Science.gov (United States)

    2011-01-01

    Vocal production requires complex planning and coordination of respiratory, laryngeal, and vocal tract movements, which are incompletely understood in most mammals. Rats produce a variety of whistles in the ultrasonic range that are of communicative relevance and of importance as a model system, but the sources of acoustic variability were mostly unknown. The goal was to identify sources of fundamental frequency variability. Subglottal pressure, tracheal airflow, and electromyographic (EMG) data from two intrinsic laryngeal muscles were measured during 22-kHz and 50-kHz call production in awake, spontaneously behaving adult male rats. During ultrasound vocalization, subglottal pressure ranged between 0.8 and 1.9 kPa. Pressure differences between call types were not significant. The relation between fundamental frequency and subglottal pressure within call types was inconsistent. Experimental manipulations of subglottal pressure had only small effects on fundamental frequency. Tracheal airflow patterns were also inconsistently associated with frequency. Pressure and flow seem to play a small role in regulation of fundamental frequency. Muscle activity, however, is precisely regulated and very sensitive to alterations, presumably because of effects on resonance properties in the vocal tract. EMG activity of cricothyroid and thyroarytenoid muscle was tonic in calls with slow or no fundamental frequency modulations, like 22-kHz and flat 50-kHz calls. Both muscles showed brief high-amplitude, alternating bursts at rates up to 150 Hz during production of frequency-modulated 50-kHz calls. A differentiated and fine regulation of intrinsic laryngeal muscles is critical for normal ultrasound vocalization. Many features of the laryngeal muscle activation pattern during ultrasound vocalization in rats are shared with other mammals. PMID:21832032

  8. A Full Vector Study of a Terrestrial Geomagnetic Record of the Porcupine Excursion (ca. 2737 ka) Recovered From a Long Volcanic Sequence at Makapuu Point, Koolau Volcano, Hawaii, USA.

    Science.gov (United States)

    Herrero-Bervera, E.; Jicha, B.

    2017-12-01

    , suggesting that the excursion corresponds to the Porcupine excursion (ca. 2737 ka) reported by Channell et al., (2016). This is the first terrestrial record of the Porcupine excursion and the age is 2-3% younger than in the reported timescale. The obtained VGPs are located over the northeastern part of Asia, close to the artic Circle and as far south as the East China Sea.

  9. Multi-PMT optical module for the KM3NeT neutrino telescope

    NARCIS (Netherlands)

    Kavatsyuk, O.; Dorosti-Hasankiadeh, Q.; Löhner, H.

    2012-01-01

    The future cubic kilometre scale neutrino telescope KM3NeT will employ a novel type of a Digital Optical Module (DOM), developed during the recent FP6 Design Study. A pressure-resistant glass sphere hosts 31 photomultiplier tubes (PMTs) of 3-in, diameter, together with all the electronics for

  10. Pressure pain thresholds increase after preconditioning 1 Hz repetitive transcranial magnetic stimulation with transcranial direct current stimulation.

    Directory of Open Access Journals (Sweden)

    Tonya M Moloney

    Full Text Available BACKGROUND: The primary motor cortex (M1 is an effective target of non-invasive cortical stimulation (NICS for pain threshold modulation. It has been suggested that the initial level of cortical excitability of M1 plays a key role in the plastic effects of NICS. OBJECTIVE: Here we investigate whether transcranial direct current stimulation (tDCS primed 1 Hz repetitive transcranial magnetic stimulation (rTMS modulates experimental pressure pain thresholds and if this is related to observed alterations in cortical excitability. METHOD: 15 healthy, male participants received 10 min 1 mA anodal, cathodal and sham tDCS to the left M1 before 15 min 1 Hz rTMS in separate sessions over a period of 3 weeks. Motor cortical excitability was recorded at baseline, post-tDCS priming and post-rTMS through recording motor evoked potentials (MEPs from right FDI muscle. Pressure pain thresholds were determined by quantitative sensory testing (QST through a computerized algometer, on the palmar thenar of the right hand pre- and post-stimulation. RESULTS: Cathodal tDCS-primed 1 Hz-rTMS was found to reverse the expected suppressive effect of 1 Hz rTMS on cortical excitability; leading to an overall increase in activity (p<0.001 with a parallel increase in pressure pain thresholds (p<0.01. In contrast, anodal tDCS-primed 1 Hz-rTMS resulted in a corresponding decrease in cortical excitability (p<0.05, with no significant effect on pressure pain. CONCLUSION: This study demonstrates that priming the M1 before stimulation of 1 Hz-rTMS modulates experimental pressure pain thresholds in a safe and controlled manner, producing a form of analgesia.

  11. Overview of results of the first phase of validation activities for the IFMIF High Flux Test Module

    Energy Technology Data Exchange (ETDEWEB)

    Arbeiter, Frederik, E-mail: frederik.arbeiter@kit.edu [Karlsruhe Institute of Technology, Karlsruhe (Germany); Chen Yuming; Dolensky, Bernhard; Freund, Jana; Heupel, Tobias; Klein, Christine; Scheel, Nicola; Schlindwein, Georg [Karlsruhe Institute of Technology, Karlsruhe (Germany)

    2012-08-15

    Highlights: Black-Right-Pointing-Pointer Validation of computational fluid dynamics (CFD) modeling approach for application in the IFMIF High Flux Test Module. Black-Right-Pointing-Pointer Fabrication of prototypes of the irradiation capsules of the IFMIF High Flux Test Module. - Abstract: The international fusion materials irradiation facility (IFMIF) is projected to create an experimentally validated database of material properties relevant for fusion reactor designs. The IFMIF High Flux Test Module is the dedicated experiment to irradiate alloys in the temperature range 250-550 Degree-Sign C and up to 50 displacements per atom per irradiation cycle. The High Flux Test Module is developed to maximize the specimen payload in the restricted irradiation volume, and to minimize the temperature spread within each specimen bundle. Low pressure helium mini-channel cooling is used to offer a high integration density. Due to the demanding thermo-hydraulic and mechanical conditions, the engineering design process (involving numerical neutronic, thermo-hydraulic and mechanical analyses) is supported by extensive experimental validation activities. This paper reports on the prototype manufacturing, thermo-hydraulic modeling experiments and component tests, as well as on mechanical testing. For the testing of the 1:1 prototype of the High Flux Test Module, a dedicated test facility, the Helium Loop Karlsruhe-Low Pressure (HELOKA-LP) has been taken into service.

  12. Dietary Flavanols: A Review of Select Effects on Vascular Function, Blood Pressure, and Exercise Performance.

    Science.gov (United States)

    Al-Dashti, Yousef A; Holt, Roberta R; Stebbins, Charles L; Keen, Carl L; Hackman, Robert M

    2018-05-02

    An individual's diet affects numerous physiological functions and can play an important role in reducing the risk of cardiovascular disease. Epidemiological and clinical studies suggest that dietary flavanols can be an important modulator of vascular risk. Diets and plant extracts rich in flavanols have been reported to lower blood pressure, especially in prehypertensive and hypertensive individuals. Flavanols may act in part through signaling pathways that affect vascular function, nitric oxide availability, and the release of endothelial-derived relaxing and constricting factors. During exercise, flavanols have been reported to modulate metabolism and respiration (e.g., maximal oxygen uptake, O 2 cost of exercise, and energy expenditure), and reduce oxidative stress and inflammation, resulting in increased skeletal muscle efficiency and endurance capacity. Flavanol-induced reductions in blood pressure during exercise may decrease the work of the heart. Collectively, these effects suggest that flavanols can act as an ergogenic aid to help delay the onset of fatigue. More research is needed to better clarify the effects of flavanols on vascular function, blood pressure regulation, and exercise performance and establish safe and effective levels of intake. Flavanol-rich foods and food products can be useful components of a healthy diet and lifestyle program for those seeking to better control their blood pressure or to enhance their physical activity. Key teaching points • Epidemiological and clinical studies indicate that dietary flavanols can reduce the risk of vascular disease. • Diets and plant extracts rich in flavanols have been reported to lower blood pressure and improve exercise performance in humans. • Mechanisms by which flavanols may reduce blood pressure function include alterations in signaling pathways that affect vascular function, nitric oxide availability, and the release of endothelial-derived relaxation and constriction factors.

  13. Susceptibility to social pressure following ventromedial prefrontal cortex damage.

    Science.gov (United States)

    Chen, Kuan-Hua; Rusch, Michelle L; Dawson, Jeffrey D; Rizzo, Matthew; Anderson, Steven W

    2015-11-01

    Social pressure influences human behavior including risk taking, but the psychological and neural underpinnings of this process are not well understood. We used the human lesion method to probe the role of ventromedial prefrontal cortex (vmPFC) in resisting adverse social pressure in the presence of risk. Thirty-seven participants (11 with vmPFC damage, 12 with brain damage outside the vmPFC and 14 without brain damage) were tested in driving simulator scenarios requiring left-turn decisions across oncoming traffic with varying time gaps between the oncoming vehicles. Social pressure was applied by a virtual driver who honked aggressively from behind. Participants with vmPFC damage were more likely to select smaller and potentially unsafe gaps under social pressure, while gap selection by the comparison groups did not change under social pressure. Participants with vmPFC damage also showed prolonged elevated skin conductance responses (SCR) under social pressure. Comparison groups showed similar initial elevated SCR, which then declined prior to making left-turn decisions. The findings suggest that the vmPFC plays an important role in resisting explicit and immediately present social pressure with potentially negative consequences. The vmPFC appears to contribute to the regulation of emotional responses and the modulation of decision making to optimize long-term outcomes. © The Author (2015). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  14. Hydrostatic pressure decreases membrane fluidity and lipid desaturase expression in chondrocyte progenitor cells.

    Science.gov (United States)

    Montagne, Kevin; Uchiyama, Hiroki; Furukawa, Katsuko S; Ushida, Takashi

    2014-01-22

    Membrane biomechanical properties are critical in modulating nutrient and metabolite exchange as well as signal transduction. Biological membranes are predominantly composed of lipids, cholesterol and proteins, and their fluidity is tightly regulated by cholesterol and lipid desaturases. To determine whether such membrane fluidity regulation occurred in mammalian cells under pressure, we investigated the effects of pressure on membrane lipid order of mouse chondrogenic ATDC5 cells and desaturase gene expression. Hydrostatic pressure linearly increased membrane lipid packing and simultaneously repressed lipid desaturase gene expression. We also showed that cholesterol mimicked and cholesterol depletion reversed those effects, suggesting that desaturase gene expression was controlled by the membrane physical state itself. This study demonstrates a new effect of hydrostatic pressure on mammalian cells and may help to identify the molecular mechanisms involved in hydrostatic pressure sensing in chondrocytes. © 2013 Elsevier Ltd. All rights reserved.

  15. Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility

    OpenAIRE

    Chintalapudi, Sumana R.; Maria, Doaa; Di Wang, Xiang; Bailey, Jessica N. Cooke; Hysi, Pirro G.; Wiggs, Janey L.; Williams, Robert W.; Jablonski, Monica M.

    2017-01-01

    textabstractGlaucoma is a multi-factorial blinding disease in which genetic factors play an important role. Elevated intraocular pressure is a highly heritable risk factor for primary open angle glaucoma and currently the only target for glaucoma therapy. Our study helps to better understand underlying genetic and molecular mechanisms that regulate intraocular pressure, and identifies a new candidate gene, Cacna2d1, that modulates intraocular pressure and a promising therapeutic, pregabalin, ...

  16. Status of development of the HTR module

    International Nuclear Information System (INIS)

    Weisbrodt, I.A.

    1989-01-01

    Growing concern about the rising global temperature of the earth due to the ''Greenhouse Effect'' is increasingly focussing worldwide interest on passively safe reactors for heat and power production. In this context the development status of the HTR-Module designed by the Siemens-Group merits strong interest. The HTR-Module has a high degree of passive safety features. Even in case of hypothetical accidents the decay heat is dissipated from the primary system to the environment by passive measures alone i.e. by heat conduction, convection and radiation. The detailed engineering for the HTR-Module continues to progress. In addition to the engineering for the layout considerable progress has been made in the detailed engineering for specific components - e.g. pressure vessel, steam generator, hot gas duct, blower etc. - and specific systems - e.g. first core, helium purification system, reactor safety system, reactor control etc. The procedure for the conceptual licence has been continued. A large number of supplementary analyses and reports have been elaborated and submitted for this procedure. Many workshop meetings have been held with the nominated experts. The hypothetical accidents have been analysed and a special report on these accidents has been submitted. The safety analyses report has been revised, taking into account the results and achievements reached during the ongoing licensing procedure. Parallel to these engineering activities outstanding in R and D work for the HTR-Module, e.g. in the field of fuel elements etc. has been continued. The HTR-Module has found worldwide interest. Respective activities are going on in Bangladesh, PR China, USSR, Indonesia etc. Relevant application studies have been carried out and/or initiated. (author). 15 refs, 16 figs

  17. Design optimization of first wall and breeder unit module size for the Indian HCCB blanket module

    Science.gov (United States)

    Deepak, SHARMA; Paritosh, CHAUDHURI

    2018-04-01

    The Indian test blanket module (TBM) program in ITER is one of the major steps in the Indian fusion reactor program for carrying out the R&D activities in the critical areas like design of tritium breeding blankets relevant to future Indian fusion devices (ITER relevant and DEMO). The Indian Lead–Lithium Cooled Ceramic Breeder (LLCB) blanket concept is one of the Indian DEMO relevant TBM, to be tested in ITER as a part of the TBM program. Helium-Cooled Ceramic Breeder (HCCB) is an alternative blanket concept that consists of lithium titanate (Li2TiO3) as ceramic breeder (CB) material in the form of packed pebble beds and beryllium as the neutron multiplier. Specifically, attentions are given to the optimization of first wall coolant channel design and size of breeder unit module considering coolant pressure and thermal loads for the proposed Indian HCCB blanket based on ITER relevant TBM and loading conditions. These analyses will help proceeding further in designing blankets for loads relevant to the future fusion device.

  18. Presence and future of thin-film photovoltaics modules; Gegenwart und Zukunft von Duennschichtphotovoltaikmodulen

    Energy Technology Data Exchange (ETDEWEB)

    Voswinckel, Sebastian [Fachhochschule Nordhausen (Germany). Inst. fuer Regenerative Energietechnik (in.RET)

    2012-07-01

    The thin-film photovoltaics is a technology with a high level of future potential of the solar energy industry. An enhanced potential of expense reduction and technical development provided a massive development of production capacities. The thin-film photovoltaics has advantageous technical properties such as a pronounced low-light behaviour and an enhanced efficiency at higher temperatures. In contrast, there are technical challenges. Beside the lower efficiency, an irreversible degradation of the transparent front contact may result especially in the case of amorphous silicon modules under certain circumstances. Effective measures for the protection of the so-called TCO corrosion have to be developed and implemented on module level and system level. Similarly, time-saving and cost-saving test methods for the evaluation of the damage potential have to be developed. The growing pricing pressure of crystalline solar cells put the thin-film industry under pressure. With respect to the technical and economic expectations aroused in the past as well as with respect to partly unsolved problems of the thin-film technology, the author of the contribution under consideration tries to present an outlook on the future chances and threats of this technology. Advantages and disadvantages of thin-film photovoltaics modules as well as possible approaches of a solution of technical difficulties are presented.

  19. Carbon capture from coal fired power plant using pressurized fluid bed technology

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Dennis; Christensen, Tor

    2010-09-15

    This presentation will discuss the use of a pressurized fluid bed boiler system and specialized carbon capture system to burn coal and generagte clean electricity. The paper will present the existing boiler and carbon capture technology and present economics, thermal performance and emissions reduction for a 100Mw module.

  20. A Study on Decontamination Process Using Atmospheric Pressure Plasma

    International Nuclear Information System (INIS)

    Kim, Yong Soo; Jeon, Sang Hwan; Jin, Dong Sik; Park, Dong Min

    2010-05-01

    Radioactive decontamination process using atmospheric pressure plasma which can be operated parallel with low vacuum cold plasma processing is studied. Two types of cold plasma torches were designed and manufactured. One of them is the cylindrical type applicable to the treatment of three-dimensional surfaces. The other is the rectangular type for the treatment of flat and large surface areas. Ar palsam was unstable but using He as a carrier gas, discharge condition was improved. Besides filtering module using pre, medium, charcoal, and HEPA filter was designed and manufactured. More intensive study for developing filtering system will be followed. Atmospheric pressure plasma decontamination process can be used to the equipment and facility wall decontamination

  1. [Effects of long-term Tai Ji Quan exercise on automatic nervous modulation in the elderly].

    Science.gov (United States)

    Guo, Feng

    2015-03-01

    To examine the effects of long-term Tai Ji Quan (Chinnese Traditional Exercise) on automatic nervous modulation in the elders. The 18 subjects from Tai Ji Quan exercise class in Liaoning University of Retired Veteran Cadres were assigned into long-term Tai Ji Quan exercise group including 10 subjects and novice group including 8 subjects. Electrocardiography, respiratory and blood pressure data were collected on the following time points: at rest before Tai Ji Qhuan exercise and 30 min or 60 min after Tai Ji Quan exercise. The subjects at rest state in the long-term Tai Ji Quan exercise group showed higher than the subjects in the novice group in resperitory rate (RR), standard deviations of normal to normal intervals (SDNN), total power (TP), low frequency power (LFP), high frequency power (HFP), normalized high frequency power (nHFP), but lower in LFP/HFP, systolic and diastolic blood pressure, and heart rate. At rest state the respiratory rate of subjects in long-term Tai Ji Quan exercise group was significantly lower than the novices. After Tai Ji Quan exercise, TP, nHFP, LFP/HFP, heart rate and systolic pressure showed significantly changes, and the change level of Tai Ji Quan on these indices was larger in Tai Ji Quan exercise group than that in the novice group. Long-term Tai Ji Quan exercise can improve vagal modulations, and tend to reduce the sympathetic modulations.

  2. Full-scale multi-ejector module for a carbon dioxide supermarket refrigeration system: Numerical study of performance evaluation

    International Nuclear Information System (INIS)

    Bodys, Jakub; Palacz, Michal; Haida, Michal; Smolka, Jacek; Nowak, Andrzej J.; Banasiak, Krzysztof; Hafner, Armin

    2017-01-01

    Highlights: • A numerical study of the full-scale multi-ejector module performance was presented. • The module was characterised by stable operation in each considered configuration. • The module showed a high total efficiency for all the operating conditions. - Abstract: The performance of fixed ejectors installed in a multi-ejector module in a carbon dioxide refrigeration system is discussed in this paper. To analyse the module operation, three-dimensional ejector models including the inlet and outlet collecting ducts were considered. The tests were performed for three of four vapour ejectors of different sizes that compose the multi-ejector pack. The testing modes included the serial and parallel operation of the fixed units in operating conditions that are characteristic for the supermarket refrigeration unit working at high ambient temperatures. All numerical simulations were performed using the validated Homogeneous Equilibrium Model implemented on the ejectorPL computational tool for typical transcritical parameters at the motive nozzle port. The detailed analysis was executed separately for the ejectors and the ducts of the module collectors. The results discussion concerned the crucial parameters for such an installation like the pressure and vapour quality distribution. Negligible influence of the motive nozzle collector and a crucial influence of the outlet collector shape was indicated. The global performance analysis showed that the multi-ejector pack provides high and stable performance of all installed ejectors over the entire range of the considered operating conditions for supermarket application. Areas of the possible pressure loss reduction and the uniformity growth in the vapour quality distribution were presented. Finally, according to the multi-ejector pack ducts analysis, the potential areas for module shape optimisation were indicated as well.

  3. High precision silicon piezo resistive SMART pressure sensor

    International Nuclear Information System (INIS)

    Brown, Rod

    2005-01-01

    Instruments for test and calibration require a pressure sensor that is precise and stable. Market forces also dictate a move away from single measurand test equipment and, certainly in the case of pressure, away from single range equipment. A pressure 'module' is required which excels in pressure measurement but is interchangble with sensors for other measurands. A communications interface for such a sensor has been specified. Instrument Digital Output Sensor (IDOS) that permits this interchanagability and allows the sensor to be inside or outside the measuring instrument. This paper covers the design and specification of a silicon diaphragm piezo resistive SMART sensor using this interface. A brief history of instrument sensors will be given to establish the background to this development. Design choices of the silicon doping, bridge energisation method, temperature sensing, signal conversion, data processing, compensation method, communications interface will be discussed. The physical format of the 'in-instrument' version will be shown and then extended to the packaging design for the external version. Test results will show the accuracy achieved exceeds the target of 0.01%FS over a range of temperatures

  4. High precision silicon piezo resistive SMART pressure sensor

    Science.gov (United States)

    Brown, Rod

    2005-01-01

    Instruments for test and calibration require a pressure sensor that is precise and stable. Market forces also dictate a move away from single measurand test equipment and, certainly in the case of pressure, away from single range equipment. A pressure `module' is required which excels in pressure measurement but is interchangble with sensors for other measurands. A communications interface for such a sensor has been specified. Instrument Digital Output Sensor (IDOS) that permits this interchanagability and allows the sensor to be inside or outside the measuring instrument. This paper covers the design and specification of a silicon diaphragm piezo resistive SMART sensor using this interface. A brief history of instrument sensors will be given to establish the background to this development. Design choices of the silicon doping, bridge energisation method, temperature sensing, signal conversion, data processing, compensation method, communications interface will be discussed. The physical format of the `in-instrument' version will be shown and then extended to the packaging design for the external version. Test results will show the accuracy achieved exceeds the target of 0.01%FS over a range of temperatures.

  5. Energy recovery by pressure retarded osmosis (PRO) in SWRO–PRO integrated processes

    KAUST Repository

    Wan, Chun Feng

    2015-11-11

    Pressure retarded osmosis (PRO) is a promising technology to reduce the specific energy consumption of a seawater reverse osmosis (SWRO) plant. In this study, it is projected that 25.6-40.7millionkWh/day of energy can be recovered globally, if the brines from SWRO are used as the draw solution and diluted to the seawater level in a PRO system. Detailed integrated SWRO-PRO processes are developed in this study with the option to form a closed-loop SWRO-PRO process that can substantially reduce the pretreatment cost of desalination. The governing mathematical models that describe both the transport phenomena on a module level and the energy flow on a system level are developed to evaluate the performances of the SWRO-PRO processes. The model aims to investigate the performance of the hollow fibers as dilution occurs and provides guidelines on hollow fiber module design and process operation. Determining the dilution factor and the corresponding operating pressure of PRO is the key to optimize the integrated process. The specific energy consumptions of three SWRO-involved processes; namely, (1) SWRO without a pressure exchanger, (2) SWRO with a pressure exchanger, and (3) SWRO with pressure exchangers and PRO are compared. The results show that the specific energy consumptions for the above three processes are 5.51, 1.79 and 1.08kWh/(m of desalinated water) for a 25% recovery SWRO plant; and 4.13, 2.27 and 1.14kWh/(m of desalinated water) for a 50% recovery SWRO plant, using either freshwater or wastewater as the feed solution in PRO.

  6. Stick-slip Cycles and Tidal Modulation of Ice Stream Flow

    Science.gov (United States)

    Lipovsky, B.; Dunham, E. M.

    2016-12-01

    The reactivation of a single dormant Antarctic ice stream would double the continent's mass imbalance. Despite importance of understanding the likelihood of such an event, direct observation of the basal processes that lead to the activation and stagnation of streaming ice are minimal. As the only ice stream undergoing stagnation, the Whillans Ice Plain (WIP) occupies a central role in our understanding of these subglacial processes. Complicating matters is the observation, from GPS records, that the WIP experiences most of its motion during episodes of rapid sliding. These sliding events are tidally modulated and separated by 12 hour periods of quiescence. We conduct numerical simulations of ice stream stick-slip cycles. Our simulations include rate- and state-dependent frictional sliding, tidal forcing, inertia, upstream loading in a cross-stream, thickness-averaged formulation. Our principal finding is that ice stream motion may respond to ocean tidal forcing with one of two end member behaviors. In one limit, tidally modulated slip events have rupture velocities that approach the shear wave speed and slip events have a duration that scales with the ice stream width divided by the shear wave speed. In the other limit, tidal modulation results in ice stream sliding velocities with lower amplitude variation but at much longer timescales, i.e. semi-diurnal and longer. This latter behavior more closely mimics the behavior of several active ice streams (Bindschadler, Rutford). We find that WIP slip events exist between these two end member behaviors: rupture velocities are far below the inertial limit yet sliding occurs only episodically. The continuum of sliding behaviors is governed by a critical ice stream width over which slip event nucleate. When the critical width is much longer than the ice stream width, slip events are unable to nucleate. The critical width depends on the subglacial effective pressure, ice thickness, and frictional and elastic constitutive

  7. Modulator-free quadrature amplitude modulation signal synthesis

    Science.gov (United States)

    Liu, Zhixin; Kakande, Joseph; Kelly, Brian; O'Carroll, John; Phelan, Richard; Richardson, David J.; Slavík, Radan

    2014-12-01

    The ability to generate high-speed on-off-keyed telecommunication signals by directly modulating a semiconductor laser’s drive current was one of the most exciting prospective applications of the nascent field of laser technology throughout the 1960s. Three decades of progress led to the commercialization of 2.5 Gbit s-1-per-channel submarine fibre optic systems that drove the growth of the internet as a global phenomenon. However, the detrimental frequency chirp associated with direct modulation forced industry to use external electro-optic modulators to deliver the next generation of on-off-keyed 10 Gbit s-1 systems and is absolutely prohibitive for today’s (>)100 Gbit s-1 coherent systems, which use complex modulation formats (for example, quadrature amplitude modulation). Here we use optical injection locking of directly modulated semiconductor lasers to generate complex modulation format signals showing distinct advantages over current and other currently researched solutions.

  8. Use of a Connected Glucose Meter and Certified Diabetes Educator Coaching to Decrease the Likelihood of Abnormal Blood Glucose Excursions: The Livongo for Diabetes Program.

    Science.gov (United States)

    Downing, Janelle; Bollyky, Jenna; Schneider, Jennifer

    2017-07-11

    The Livongo for Diabetes Program offers members (1) a cellular technology-enabled, two-way messaging device that measures blood glucose (BG), centrally stores the glucose data, and delivers messages back to the individual in real time; (2) unlimited BG test strips; and (3) access to a diabetes coaching team for questions, goal setting, and automated support for abnormal glucose excursions. The program is sponsored by at-risk self-insured employers, health plans and provider organizations where it is free to members with diabetes or it is available directly to the person with diabetes where they cover the cost. The objective of our study was to evaluate BG data from 4544 individuals with diabetes who were enrolled in the Livongo program from October 2014 through December 2015. Members used the Livongo glucose meter to measure their BG levels an average of 1.8 times per day. We estimated the probability of having a day with a BG reading outside of the normal range (70-180 mg/dL, or 3.9-10.0 mmol/L) in months 2 to 12 compared with month 1 of the program, using individual fixed effects to control for individual characteristics. Livongo members experienced an average 18.4% decrease in the likelihood of having a day with hypoglycemia (BG 180 mg/dL) in months 2-12 compared with month 1 as the baseline. The biggest impact was seen on hyperglycemia for nonusers of insulin. We do not know all of the contributing factors such as medication or other treatment changes during the study period. These findings suggest that access to a connected glucose meter and certified diabetes educator coaching is associated with a decrease in the likelihood of abnormal glucose excursions, which can lead to diabetes-related health care savings. ©Janelle Downing, Jenna Bollyky, Jennifer Schneider. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 11.07.2017.

  9. On Better Estimating and Normalizing the Relationship between Clinical Parameters: Comparing Respiratory Modulations in the Photoplethysmogram and Blood Pressure Signal (DPOP versus PPV

    Directory of Open Access Journals (Sweden)

    Paul S. Addison

    2015-01-01

    Full Text Available DPOP (ΔPOP or Delta-POP is a noninvasive parameter which measures the strength of respiratory modulations present in the pulse oximeter waveform. It has been proposed as a noninvasive alternative to pulse pressure variation (PPV used in the prediction of the response to volume expansion in hypovolemic patients. We considered a number of simple techniques for better determining the underlying relationship between the two parameters. It was shown numerically that baseline-induced signal errors were asymmetric in nature, which corresponded to observation, and we proposed a method which combines a least-median-of-squares estimator with the requirement that the relationship passes through the origin (the LMSO method. We further developed a method of normalization of the parameters through rescaling DPOP using the inverse gradient of the linear fitted relationship. We propose that this normalization method (LMSO-N is applicable to the matching of a wide range of clinical parameters. It is also generally applicable to the self-normalizing of parameters whose behaviour may change slightly due to algorithmic improvements.

  10. On better estimating and normalizing the relationship between clinical parameters: comparing respiratory modulations in the photoplethysmogram and blood pressure signal (DPOP versus PPV).

    Science.gov (United States)

    Addison, Paul S; Wang, Rui; Uribe, Alberto A; Bergese, Sergio D

    2015-01-01

    DPOP (ΔPOP or Delta-POP) is a noninvasive parameter which measures the strength of respiratory modulations present in the pulse oximeter waveform. It has been proposed as a noninvasive alternative to pulse pressure variation (PPV) used in the prediction of the response to volume expansion in hypovolemic patients. We considered a number of simple techniques for better determining the underlying relationship between the two parameters. It was shown numerically that baseline-induced signal errors were asymmetric in nature, which corresponded to observation, and we proposed a method which combines a least-median-of-squares estimator with the requirement that the relationship passes through the origin (the LMSO method). We further developed a method of normalization of the parameters through rescaling DPOP using the inverse gradient of the linear fitted relationship. We propose that this normalization method (LMSO-N) is applicable to the matching of a wide range of clinical parameters. It is also generally applicable to the self-normalizing of parameters whose behaviour may change slightly due to algorithmic improvements.

  11. Report on achievements in fiscal 1998. Development of technologies to put photovoltaic power generation systems into practical use - Development of solar beam power generation and utilization systems and ancillary technologies (Research and development of building material integrated solar cell modules - modules with new multi-layer structure); 1998 nendo taiyoko hatsuden system jitsuyoka gijutsu kaihatsu seika hokokusho. Taiyoko hatsuden riyo system shuhen gijutsu no kenkyu kaihatsu (shinkenzai ittaigata taiyo denchi module no kenkyu kaihatsu (shinfukuso kozo module))

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    Development is being made on a panel type module that can be used together with an air bubble concrete board (ALC board), and is provided with design characteristics. The development work includes trial fabrication and evaluation of a module with new multi-layer structure, and development of a technology to unitize cells and submodules, and a systematizing method. In the trial fabrication and evaluation, flame retardant and uninflammable modules using fluororesin, and modules with as large area as 4 m{sup 2} were fabricated on a trial basis, in addition to the modules with the basic structure. These modules were given evaluations on such wall material properties as wind pressure resistance, heat and cracking resistance, and fire resistance. In a deformation resistance test considering the integrated use with the ALC board, the developed modules showed a good result. In developing the cells with design characteristics, discussions were given on the inter-cell wiring methods. Development was made on a method to establish a unit structure based on the design and size of a building. In developing the systematization method, the trial fabrication method was applied to a module with lamination structure, a module integrated with the ALC board, and a large-area hollow module to have fabricated the top-light spandrels. (NEDO)

  12. Measurement and evaluation of pumping speed and gas discharge characteristics of titanium getter pump by conductance modulation method

    International Nuclear Information System (INIS)

    Terada, Keiko; Okano, Tatsuo; Tsuji, Hiroshi.

    1989-01-01

    The conductance modulation method is designed to determine the pumping speed from a known conductance. With the method, the intrinsic pumping speed Sp and net pumping speed S * can be determined in a wide range up to near the ultimate pressure. In the present study, the pumping speed and gas discharge rate of a titanium getter pump at 77K are analyzed, and the results are compared with measurements made at room temperature. The pressure in a vacuum chamber depends on the gas load and the pumping speed. The pressure varies from P A to P B as the conductance of the orifice is changed from C A to C B . The ultimate pressure also changes from P AO to P BO . The intrinsic and net pumping speeds can be calculated from P A , P B , P AO and P BO . The major feature of the conductance modulation method is that the intrinsic and net pumping speeds can be determined from a change in the conductance without knowing the sensitivity of the vacuum meter or the flow rate of gas entering the chamber from outside. With this feature, the method is very effective for measuring the balance between the gas discharge and pumping speed near the ultimate pressure. (N.K.)

  13. Effect of upper body position on arterial stiffness: influence of hydrostatic pressure and autonomic function.

    Science.gov (United States)

    Schroeder, Elizabeth C; Rosenberg, Alexander J; Hilgenkamp, Thessa I M; White, Daniel W; Baynard, Tracy; Fernhall, Bo

    2017-12-01

    To evaluate changes in arterial stiffness with positional change and whether the stiffness changes are due to hydrostatic pressure alone or if physiological changes in vasoconstriction of the conduit arteries play a role in the modulation of arterial stiffness. Thirty participants' (male = 15, 24 ± 4 years) upper bodies were positioned at 0, 45, and 72° angles. Pulse wave velocity (PWV), cardio-ankle vascular index, carotid beta-stiffness index, carotid blood pressure (cBP), and carotid diameters were measured at each position. A gravitational height correction was determined using the vertical fluid column distance (mmHg) between the heart and carotid artery. Carotid beta-stiffness was calibrated using three methods: nonheight corrected cBP of each position, height corrected cBP of each position, and height corrected cBP of the supine position (theoretical model). Low frequency systolic blood pressure variability (LFSAP) was analyzed as a marker of sympathetic activity. PWV and cardio-ankle vascular index increased with position (P hydrostatic pressure. Arterial stiffness indices based on Method 2 were not different from Method 3 (P = 0.65). LFSAP increased in more upright positions (P pressure did not (P > 0.05). Arterial stiffness increases with a more upright body position. Carotid beta-stiffness needs to be calibrated accounting for hydrostatic effects of gravity if measured in a seated position. It is unclear why PWV increased as this increase was independent of blood pressure. No difference between Methods 2 and 3 presumably indicates that the beta-stiffness increases are only pressure dependent, despite the increase in vascular sympathetic modulation.

  14. Tricuspid Annular Plane Systolic Excursion and Its Association with Mortality in Critically Ill Patients.

    Science.gov (United States)

    Gajanana, Deepakraj; Seetha Rammohan, Harish; Alli, Oluseun; Romero-Corral, Abel; Purushottam, Bhaskar; Ponamgi, Shiva; Figueredo, Vincent M; Pressman, Gregg S

    2015-08-01

    Transient left ventricular dysfunction can occur under conditions of extreme emotional or physiological stress. There is little data on right ventricular function in such situations. One hundred twenty patients admitted to an ICU with a noncardiac illness were studied. Those with documented coronary disease, ejection fraction <40%, sepsis, or intracranial hemorrhage were excluded. Echocardiograms were performed within 24 hours of admission. Tricuspid annular plane systolic excursion (TAPSE) was measured to assess right ventricular systolic function. Plasma catecholamines (norepinephrine, epinephrine, dopamine) were measured on admission. Clinical and demographic data were collected, along with data on ICU length of stay (LOS), hospital LOS, and in-hospital and long-term mortality. TAPSE was tested for correlation with adverse outcomes and length of stay. Mean TAPSE for the group was 2.05 ± 0.66 cm. Based on area under the ROC curve analysis, TAPSE <2.4 cm was the best cutoff for predicting in-hospital and long-term mortality. There were 13 in-hospital deaths, 12 in the group with TAPSE <2.4 cm and one among those with TAPSE ≥2.4 cm. On multivariate analysis, TAPSE <2.4 cm was a significant predictor of in-hospital mortality (χ(2)  = 4.6, P = 0.03). When tested against hospital LOS, an inverse correlation was found (P = 0.04). No association was found between TAPSE and catecholamine levels. Right ventricular systolic function, as assessed by TAPSE, has important prognostic value in critically ill patients. Mean values were lower in patients who died in-hospital versus those who survived to discharge. In addition, patients with TAPSE <2.4 cm had a longer hospital length of stay. © 2015, Wiley Periodicals, Inc.

  15. Astronauts Work in the Russian Zvezda Service Module

    Science.gov (United States)

    2001-01-01

    Astronauts Frank L. Culbertson, Jr. (left), Expedition Three mission commander, and Daniel W. Bursch, Expedition Four flight engineer, work in the Russian Zvezda Service Module on the International Space Station (ISS). Zvezda is linked to the Russian built Functional Cargo Block (FGB), or Zarya, the first component of the ISS. Zarya was launched on a Russian Proton rocket prior to the launch of Unity. The third component of the ISS, Zvezda (Russian word for star), the primary Russian contribution to the ISS, was launched by a three-stage Proton rocket on July 12, 2000. Zvezda serves as the cornerstone for early human habitation of the Station, providing living quarters, a life support system, electrical power distribution, a data processing system, a flight control system, and a propulsion system. It also provides a communications system that includes remote command capabilities from ground flight controllers. The 42,000 pound module measures 43 feet in length and has a wing span of 98 feet. Similar in layout to the core module of Russia's Mir space station, it contains 3 pressurized compartments and 13 windows that allow ultimate viewing of Earth and space.

  16. To freeze or not to freeze? Affective and cognitive perturbations have markedly different effects on postural control

    NARCIS (Netherlands)

    Stins, J.F.; Roerdink, M.; Beek, P.J.

    2011-01-01

    Similar effects have been reported for diverting attention from postural control and increased anxiety on the characteristics of center-of-pressure (COP) time series (decreased excursions and elevated mean power frequency). These effects have also received similar interpretations in terms of

  17. Pressure broadening and pressure shift of diatomic iodine at 675 nm

    Science.gov (United States)

    Wolf, Erich N.

    Doppler-limited, steady-state, linear absorption spectra of 127 I2 (diatomic iodine) near 675 nm were recorded with an internally-referenced wavelength modulation spectrometer, built around a free-running diode laser using phase-sensitive detection, and capable of exceeding the signal-to-noise limit imposed by the 12-bit data acquisition system. Observed I2 lines were accounted for by published spectroscopic constants. Pressure broadening and pressure shift coefficients were determined respectively from the line-widths and line-center shifts as a function of buffer gas pressure, which were determined from nonlinear regression analysis of observed line shapes against a Gaussian-Lorentzian convolution line shape model. This model included a linear superposition of the I2 hyperfine structure based on changes in the nuclear electric quadrupole coupling constant. Room temperature (292 K) values of these coefficients were determined for six unblended I 2 lines in the region 14,817.95 to 14,819.45 cm-1 for each of the following buffer gases: the atoms He, Ne, Ar, Kr, and Xe; and the molecules H2, D2, N2, CO2, N2O, air, and H2O. These coefficients were also determined at one additional temperature (388 K) for He and CO2, and at two additional temperatures (348 and 388 K) for Ar. Elastic collision cross-sections were determined for all pressure broadening coefficients in this region. Room temperature values of these coefficients were also determined for several low-J I2 lines in the region 14,946.17 to 14,850.29 cm-1 for Ar. A line shape model, obtained from a first-order perturbation solution of the time-dependent Schrodinger equation for randomly occurring interactions between a two-level system and a buffer gas treated as step-function potentials, reveals a relationship between the ratio of pressure broadening to pressure shift coefficients and a change in the wave function phase-factor, interpreted as reflecting the "cause and effect" of state-changing events in the

  18. Image quality testing of assembled IR camera modules

    Science.gov (United States)

    Winters, Daniel; Erichsen, Patrik

    2013-10-01

    Infrared (IR) camera modules for the LWIR (8-12_m) that combine IR imaging optics with microbolometer focal plane array (FPA) sensors with readout electronics are becoming more and more a mass market product. At the same time, steady improvements in sensor resolution in the higher priced markets raise the requirement for imaging performance of objectives and the proper alignment between objective and FPA. This puts pressure on camera manufacturers and system integrators to assess the image quality of finished camera modules in a cost-efficient and automated way for quality control or during end-of-line testing. In this paper we present recent development work done in the field of image quality testing of IR camera modules. This technology provides a wealth of additional information in contrast to the more traditional test methods like minimum resolvable temperature difference (MRTD) which give only a subjective overall test result. Parameters that can be measured are image quality via the modulation transfer function (MTF) for broadband or with various bandpass filters on- and off-axis and optical parameters like e.g. effective focal length (EFL) and distortion. If the camera module allows for refocusing the optics, additional parameters like best focus plane, image plane tilt, auto-focus quality, chief ray angle etc. can be characterized. Additionally, the homogeneity and response of the sensor with the optics can be characterized in order to calculate the appropriate tables for non-uniformity correction (NUC). The technology can also be used to control active alignment methods during mechanical assembly of optics to high resolution sensors. Other important points that are discussed are the flexibility of the technology to test IR modules with different form factors, electrical interfaces and last but not least the suitability for fully automated measurements in mass production.

  19. PPARγ ligands decrease hydrostatic pressure-induced platelet aggregation and proinflammatory activity.

    Directory of Open Access Journals (Sweden)

    Fang Rao

    Full Text Available Hypertension is known to be associated with platelet overactivity, but the direct effects of hydrostatic pressure on platelet function remain unclear. The present study sought to investigate whether elevated hydrostatic pressure is responsible for platelet activation and to address the potential role of peroxisome proliferator-activated receptor-γ (PPARγ. We observed that hypertensive patients had significantly higher platelet volume and rate of ADP-induced platelets aggregation compared to the controls. In vitro, Primary human platelets were cultured under standard (0 mmHg or increased (120, 180, 240 mmHg hydrostatic pressure for 18 h. Exposure to elevated pressure was associated with morphological changes in platelets. Platelet aggregation and PAC-1 (the active confirmation of GPIIb/IIIa binding were increased, CD40L was translocated from cytoplasm to the surface of platelet and soluble CD40L (sCD40L was released into the medium in response to elevated hydrostatic pressure (180 and 240 mmHg. The PPARγ activity was up-regulated as the pressure was increased from 120 mmHg to 180 mmHg. Pressure-induced platelet aggregation, PAC-1 binding, and translocation and release of CD40L were all attenuated by the PPARγ agonist Thiazolidinediones (TZDs. These results demonstrate that platelet activation and aggregation are increased by exposure to elevated pressure and that PPARγ may modulate platelet activation induced by high hydrostatic pressure.

  20. PPARγ ligands decrease hydrostatic pressure-induced platelet aggregation and proinflammatory activity.

    Science.gov (United States)

    Rao, Fang; Yang, Ren-Qiang; Chen, Xiao-Shu; Xu, Jin-Song; Fu, Hui-Min; Su, Hai; Wang, Ling

    2014-01-01

    Hypertension is known to be associated with platelet overactivity, but the direct effects of hydrostatic pressure on platelet function remain unclear. The present study sought to investigate whether elevated hydrostatic pressure is responsible for platelet activation and to address the potential role of peroxisome proliferator-activated receptor-γ (PPARγ). We observed that hypertensive patients had significantly higher platelet volume and rate of ADP-induced platelets aggregation compared to the controls. In vitro, Primary human platelets were cultured under standard (0 mmHg) or increased (120, 180, 240 mmHg) hydrostatic pressure for 18 h. Exposure to elevated pressure was associated with morphological changes in platelets. Platelet aggregation and PAC-1 (the active confirmation of GPIIb/IIIa) binding were increased, CD40L was translocated from cytoplasm to the surface of platelet and soluble CD40L (sCD40L) was released into the medium in response to elevated hydrostatic pressure (180 and 240 mmHg). The PPARγ activity was up-regulated as the pressure was increased from 120 mmHg to 180 mmHg. Pressure-induced platelet aggregation, PAC-1 binding, and translocation and release of CD40L were all attenuated by the PPARγ agonist Thiazolidinediones (TZDs). These results demonstrate that platelet activation and aggregation are increased by exposure to elevated pressure and that PPARγ may modulate platelet activation induced by high hydrostatic pressure.