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Sample records for premenstrual syndrome-like symptoms

  1. Gynecological management of premenstrual symptoms.

    Science.gov (United States)

    Shulman, Lee P

    2010-10-01

    The vast majority of menstruating women experience uncomfortable symptoms during the premenstrual phase of their menstrual cycles. Although many women do not require specific treatment of their symptoms, approximately 20% to 50% report moderate to severe premenstrual symptoms and about 5% meet the diagnostic criteria for premenstrual dysphoric disorder, the most severe manifestation of premenstrual symptoms. While the etiology of premenstrual symptoms remains unclear, several theories have implicated sex steroids and neurotransmitters in the development and manifestation of symptoms. Further complicating the delineation of etiology is that premenstrual symptoms can be somatic, psychological, or behavioral, as well as a combination of all three. Developing successful interventions for premenstrual symptoms has thus been challenging, with interventions focused on a particular aspect of premenstrual symptomatology. Treatments for premenstrual symptoms include lifestyle changes, cognitive behavioral therapies, and pharmacologic agents including ovulation suppression regimens, antidepressant medications, and anxiolytics.

  2. Premenstrual symptoms and smoking-related expectancies.

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    Pang, Raina D; Bello, Mariel S; Stone, Matthew D; Kirkpatrick, Matthew G; Huh, Jimi; Monterosso, John; Haselton, Martie G; Fales, Melissa R; Leventhal, Adam M

    2016-06-01

    Given that prior research implicates smoking abstinence in increased premenstrual symptoms, tobacco withdrawal, and smoking behaviors, it is possible that women with more severe premenstrual symptoms have stronger expectancies about the effects of smoking and abstaining from smoking on mood and withdrawal. However, such relations have not been previously explored. This study examined relations between premenstrual symptoms experienced in the last month and expectancies that abstaining from smoking results in withdrawal (i.e., smoking abstinence withdrawal expectancies), that smoking is pleasurable (i.e., positive reinforcement smoking expectancies), and smoking relieves negative mood (i.e., negative reinforcement smoking expectancies). In a cross-sectional design, 97 non-treatment seeking women daily smokers completed self-report measures of smoking reinforcement expectancies, smoking abstinence withdrawal expectancies, premenstrual symptoms, mood symptoms, and nicotine dependence. Affect premenstrual symptoms were associated with increased negative reinforcement smoking expectancies, but not over and above covariates. Affect and pain premenstrual symptoms were associated with increased positive reinforcement smoking expectancies, but only affect premenstrual symptoms remained significant in adjusted models. Affect, pain, and water retention premenstrual symptoms were associated with increased smoking abstinence withdrawal expectancies, but only affect premenstrual symptoms remained significant in adjusted models. Findings from this study suggest that addressing concerns about withdrawal and alternatives to smoking may be particularly important in women who experience more severe premenstrual symptoms, especially affect-related changes.

  3. EVALUATION OF NURSING STUDENTS' PREMENSTRUAL SYMPTOMS

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    Kerime Derya TASCI

    2006-12-01

    Full Text Available This study was conducted as a descriptive study for the purpose of determining the kinds of premenstrual symptoms that Denizli Health Sciences School Nursing Students experience and what they do to treat them. The research population included the 126 female students in the Pamukkale University Denizli Health Sciences School Nursing School. Data collects in the classroom. In the examination of the students' menstrual complaints, 47.5% experienced back pain, 59% experienced abdominal pain, 44.3% experienced irritability, 39.3% experienced breast sensitivity/pain, 41% experienced facial or body acne and 32.8% experienced increased appetite every cycle. An examination of the students' responses about procedures during menstruation, 86.9% stated that having a bath was not contraindicated and 60.7% that aspirin-type analgesics should not be used for dysmenorrhea. 77.9% of the students stated that it was normal to have pain during menstruation and 63.9% that walking is beneficial for decreasing menstrual pain. There was a significant difference in the students' answers based on age group and class for experience of menstrual complaints and procedures used (p<0.05. The students' were lived premenstrual symptoms and they had insufficient knowledge of procedures for relief. [TAF Prev Med Bull 2006; 5(6.000: 434-443

  4. Premenstrual Symptom Screening Tool: A Useful Tool for DSM-5 Premenstrual Dysphoric Disorder

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    Kadir Ozdel

    2014-03-01

    Full Text Available Aim: To assess the usefulness of Premenstrual Symptoms Screening Tool (PSST in detecting Premenstrual Dysphoric Syndrome (PMDD and Premenstrual Syndrome (PMS in a Turkish sample. Material and Method: One hundred and eighteen women were included in the study. Participants were menstruating women, between the ages of 18 and 49 years who work in various departments of Diskapi Yildirim Beyazit Teaching and Research Hospital. Sociodemographic data collection form, PSST, and Symptom Check List (SCL-90-R were given to the participants, filled out by participants and checked out by researchers. Participants were divided into three groups (i.e., women with subthreshold premenstrual symptoms, women with PMDD, and women with PMS according to the scores they get on the PSST. These groups were compared according to PSST scores and SCL-90-R scores. Results: Internal consistency was excellent (Cronbach %u03B1=0.928 for the items of the tool. In this sample, the prevalence of the PMDD and PMS were 15.2 % (n=18 and 32.2 % (n=38 respectively. When we compare the scores on SCL-90-R subscales there were significant differences between the PMDD, PMS, and women with subthreshold groups. Besides there were significant differences for the three groups in terms of percentages of women who reported moderate to severe symptoms on the four items that are essential to PMDD diagnosis. Discussion: Premenstrual Symptoms Screening Tool is a useful tool to detect candidates for PMDD and moderate to severe PMS.

  5. Characterization of symptoms and edema distribution in premenstrual syndrome

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    Tacani, Pascale Mutti; Ribeiro, Danielle de Oliveira; Barros Guimarães, Barbara Evelyn; Machado, Aline Fernanda Perez; Tacani, Rogério Eduardo

    2015-01-01

    Background Premenstrual syndrome is a group of symptoms linked to the menstrual cycle, and edema is among these symptoms. Physiotherapy is often sought by many patients for the treatment of edema; however, for an adequate prescription of physiotherapeutic procedures, the distribution of edema throughout the body has yet to be characterized. Objective To determine the most frequent symptoms and body regions that present with edema in women during the premenstrual period. Subjects and methods Sixty women with a mean age of 24.6±4.7 years were evaluated during their premenstrual (between days 21 and 28) and menstrual period (between days 1 and 3), and the collected data included body mass, height, biotype (body-fat distribution), face, breast, limb-circumference measurements, and limb-volume estimate, and an adapted version of the Premenstrual Symptoms Screening Tool was used. Statistical analysis was performed using Student’s t-test and the test for equality of two proportions (P≤0.05). Results Premenstrual syndrome was identified in 91.7% of the women, and the most frequent symptoms were irritability (73.33%) and physical symptoms, including swelling (65%), and anxiety (58.3%). Edema was detected in the following areas: facial, epigastric, mammary, umbilical, and pubic, the mid-third of the arms, distal forearm, in both thighs and in the mid-third of the legs determined by circumference measurements, and in both upper and lower limbs, according to the estimated volume. Conclusion In this study population, the most frequent symptoms were irritability, physical symptoms, and anxiety, with distribution of edema in the face, breast, abdomen, pubic area, distal upper limb, and proximal lower limb. PMID:25792857

  6. An interventional study (calcium supplementation & health education) on premenstrual syndrome - effect on premenstrual and menstrual symptoms

    OpenAIRE

    Shailesh Sutariya, Nitiben Talsania, Chintul Shah

    2011-01-01

    The study was conducted to study the effect of calcium supplementation on Premenstrual and Menstrual Symptoms. It was a one year follow-up prospective, randomized controlled interventional study. After the initial 2-cycle screening phase, a total of 215 healthy premenopausal women were enrolled in the study group calcium supplementation(500 BD) of the trial and 140 subjects either the relatives or neighbors of the study population were enrolled as control group health, nutrition, hygiene educ...

  7. Daily symptom ratings for studying premenstrual dysphoric disorder : A review

    NARCIS (Netherlands)

    Bosman, Renske C.; Jung, Sophie E.; Miloserdov, Kristina; Schoevers, Robert A.; aan het Rot, Marije

    2016-01-01

    Background: To review how daily symptom ratings have been used in research into premenstrual dysphoric disorder (PMDD), and to discuss opportunities for the future. Methods: PsycINFO and Medline were systematically searched, resulting in the inclusion of 75 studies in which (1) participants met the

  8. Lower peripheral circulation in eumenorrheic young women with premenstrual symptoms

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    Tatsumi Noriyuki

    2007-03-01

    Full Text Available Abstract Background A majority of women from all cultures and socioeconomic levels experience diverse psychosomatic and behavioral symptoms premenstrually, a phenomenon commonly termed premenstrual syndrome, although symptoms and discomfort levels vary from woman to woman. The underlying pathological mechanisms of premenstrual syndrome remain unknown; however, altered function or even slight disorder of the blood circulation system, which contributes to the orchestrations of the human internal environment, could cause bio-psychological changes leading to complaints and ultimately compromising a woman's overall health. The present study, therefore, investigates to what extent and how the menstrual cyclicity of peripheral circulation is associated with premenstrual symptomatology. Methods Twenty-one eumenorrheic young women participated in this study. All subjects were investigated during the follicular and late luteal phases. Cycle phase was determined by the onset of menstruation and oral temperature and was verified by concentrations of ovarian hormones, estrone, and pregnanediol in a urine sample taken early in the morning. Peripheral circulation was evaluated with the Astrim (Sysmex, Kobe, a portable non-invasive monitoring device using the principle of near-infrared spectroscopy, which calculates the venous oxygenation index (VOI based on the ratio of light absorption of oxyhemoglobin and deoxyhemoglobin, a proven reliable indicator of peripheral blood circulation. The Menstrual Distress Questionnaire was applied to measure physical, emotional, and behavioral symptoms accompanying the menstrual cycle of the subjects. Results The oral temperature and urinary ovarian hormones adjusted for creatinine significantly increased in the late luteal phase in all subjects. While 10 subjects experienced no symptoms during the menstrual cycle, 11 subjects had apparent physical and psychological discomfort in the late luteal phase. We found that VOI

  9. Characterization of symptoms and edema distribution in premenstrual syndrome

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    Tacani PM

    2015-03-01

    Full Text Available Pascale Mutti Tacani,1 Danielle de Oliveira Ribeiro,1 Barbara Evelyn Barros Guimarães,1 Aline Fernanda Perez Machado,2 Rogério Eduardo Tacani1,2 1Physical Therapy Department, São Camilo University Center, 2Physical Therapy Department, São Paulo City University (UNICID, São Paulo, Brazil Background: Premenstrual syndrome is a group of symptoms linked to the menstrual cycle, and edema is among these symptoms. Physiotherapy is often sought by many patients for the treatment of edema; however, for an adequate prescription of physiotherapeutic procedures, the distribution of edema throughout the body has yet to be characterized. Objective: To determine the most frequent symptoms and body regions that present with edema in women during the premenstrual period.Subjects and methods: Sixty women with a mean age of 24.6±4.7 years were evaluated during their premenstrual (between days 21 and 28 and menstrual period (between days 1 and 3, and the collected data included body mass, height, biotype (body-fat distribution, face, breast, limb-circumference measurements, and limb-volume estimate, and an adapted version of the Premenstrual Symptoms Screening Tool was used. Statistical analysis was performed using Student’s t-test and the test for equality of two proportions (P≤0.05.Results: Premenstrual syndrome was identified in 91.7% of the women, and the most frequent symptoms were irritability (73.33% and physical symptoms, including swelling (65%, and anxiety (58.3%. Edema was detected in the following areas: facial, epigastric, mammary, umbilical, and pubic, the mid-third of the arms, distal forearm, in both thighs and in the mid-third of the legs determined by circumference measurements, and in both upper and lower limbs, according to the estimated volume.Conclusion: In this study population, the most frequent symptoms were irritability, physical symptoms, and anxiety, with distribution of edema in the face, breast, abdomen, pubic area, distal

  10. Emotional regulation difficulties and premenstrual symptoms among Israeli students.

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    Reuveni, Inbal; Dan, Rotem; Segman, Ronen; Evron, Ron; Laufer, Sofia; Goelman, Gadi; Bonne, Omer; Canetti, Laura

    2016-12-01

    Premenstrual dysphoric disorder (PMDD) is a severe form of premenstrual syndrome (PMS) reported to affect 3-8 % of women of reproductive age and resulting in marked emotional and occupational impairment. Despite its prevalence, the etiology of PMDD is largely unknown, and patients remain mostly undiagnosed and poorly treated. It has been suggested that PMDD is a manifestation of underlying depressive disorder which is associated with the inability to regulate emotions in an adaptive manner. Therefore, we hypothesized that women with PMDD would exhibit increased difficulty with emotional regulation. A total of 648 female Israeli college students were assessed by the Premenstrual Symptoms Screening Tool (PSST) and the Difficulties in Emotion Regulation Scale (DERS). Of these women, 166 (25.6 %) met the criteria for PMS. Sixty-four (9.9 %) suffered from PMDD. More emotion regulation deficits were observed in the PMDD and PMS groups compared to the control group. Furthermore, there were more emotional regulation deficits among the predominantly psychological and mixed symptom subtype compared to the predominantly physical symptom subtype group. This is the first study to report an association between emotional dysregulation and PMDD. These findings may lead to development of more individually tailored treatment protocols focused on improving emotional regulation techniques.

  11. Patterns and Predictors of Premenstrual Symptoms among Females Working in a Psychiatry Hospital.

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    Kumari, Sunita; Sachdeva, Ankur

    2016-01-01

    Introduction. Premenstrual syndrome presents with vague psychological, somatic, or biological symptoms. It may be seen more commonly in a specific profile of patients. We try to evaluate the patterns and predictors of premenstrual symptoms among females working in a tertiary care psychiatry hospital. Methodology. We recruited working females at a tertiary care psychiatry hospital in India, through purposive sampling, and assessed them cross-sectionally. Premenstrual Symptom Checklist was used to assess the frequency and distribution of premenstrual symptoms, which were correlated with various sociodemographic variables to evaluate the predictors for premenstrual symptoms. Results. 150 working females were included, belonging to different sociodemographic profile. Somatic symptoms (backache, joint and muscles pain, and fatiguability) were most commonly reported followed by psychological (irritability and losing temper easily) and biological symptoms (increased micturition). Premenstrual symptoms were seen more commonly in women with higher educational status and nursing profession and residing in nuclear families (p working females. Somatic symptoms such as backache and joint pains predominate over psychobiological symptoms. Women with higher educational status and professions like nursing belonging to nuclear families are more prone to these symptoms. Attention needs to be given to premenstrual symptoms in such population of working females.

  12. An interventional study (calcium supplementation & health education on premenstrual syndrome - effect on premenstrual and menstrual symptoms

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    Shailesh Sutariya, Nitiben Talsania, Chintul Shah, Mitesh Patel

    2011-01-01

    Full Text Available The study was conducted to study the effect of calcium supplementation on Premenstrual and Menstrual Symptoms. It was a one year follow-up prospective, randomized controlled interventional study. After the initial 2-cycle screening phase, a total of 215 healthy premenopausal women were enrolled in the study group calcium supplementation(500 BD of the trial and 140 subjects either the relatives or neighbors of the study population were enrolled as control group health, nutrition, hygiene education of the trial. By the second and third treatment months, all symptoms except for fatigue and insomnia showed a significant response to calcium. For the symptom of low backache, the mean screening score was significantly higher than the control group score (0.82±0.74 vs 0.69±0.66,p=0.033 and became significantly lower than the control group score by the end of third treatment cycle. (0.30±0.45 vs 0.49±0.59,p<0.01. Nearly half (55% of the women in the study group reported ?50% improvement and one-third (30% of the women in study group reported ?75% improvement. Significantly lower symptoms score was detected in the urban sites during the first treatment phase with calcium and during the final treatment phase

  13. Premenstrual vaginal colonization of Candida and symptoms of vaginitis.

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    Watson, Cathy J; Grando, Danilla; Garland, Suzanne M; Myers, Stephen; Fairley, Christopher K; Pirotta, Marie

    2012-11-01

    Although premenstrual exacerbation of vulvovaginal symptoms attributed to Candida spp. is well documented, the causation of these symptoms is not well understood. This study describes the daily vaginal colonization of Candida in three women. A single pilot study was designed to test the methodology of the proposed randomized controlled trial, Garlic and Candida. This study reports the colonization of Candida spp. in three women. Ten women aged 18-50 who reported at least one episode of vulvovaginal candidiasis were recruited by the University of Melbourne. Each participant took daily vaginal swabs for 2 weeks during the luteal phase of their menstrual cycle, which were analysed for quantitative colony counts of Candida spp. Of these, three women were colonized with Candida spp. For the first time, to our knowledge, daily colonization of Candida during the luteal phase of the menstrual cycle is described in three women, demonstrating an increase in the colony count preceding symptom development. This small study demonstrated the colonization of Candida spp. during the luteal phase of the menstrual cycle in three women. Candida colonization is poorly understood, yet investigating the relevance of the link between symptom exacerbation and the menstrual cycle in those women who experience recurrent episodes of vulvovaginal candidiasis may influence the management of this condition.

  14. The Relationship Between Severity of Premenstrual Syndrome and Psychiatric Symptoms

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    Maryam Shirmohammadi

    2012-04-01

    Full Text Available Objective: Premenstrual syndrome is a common disorder experienced by up to 50% of women during reproductive age. The prevalence of severe form of PMS (PMDD is 3 % to 8%. Psychiatric disorders in PMS patients have resulted in significant morbidity and in some cases caused resistance to the treatment process Material and Method: 390 participants (264 with PMS/PMDD, and 126 healthy students of University of Guilan who completed the demographic questionnaire, daily symptom rating (DSR and the checklist 90-revised (SCL-90-R took part in this study. This study was conducted using a cross sectional method. Results: According to repeated measure variance, the mean scores of psychiatric symptoms (Depression, Anxiety, Aggression, Interpersonal sensitivity in the PMS group were significantly higher than the healthy group (p< 0/05, and increase in severity of PMS from mild to severe was accompanied by increase in mean score of these subscales. There was a significant difference in mean score of depression, anxiety, aggression and interpersonal sensitivity between the 3rd and the 13th day of the cycle. Significant effect of the DSR grouping (PMS and Healthy group and time interaction emerged in interpersonal sensitivity and aggression, significant effect on the DSR grouping (Mild, Moderate, Severer and time interaction demonstrated in interpersonal sensitivity. Conclusion: Patients with prospective confirmed PMDD seemed to suffer from psychiatric symptoms. Therefore, recognizing co-morbid psychiatric symptoms in patients with PMDD is of prime importance. All healthcare providers should be sensitive to mental status of women with PMS.

  15. Effects of ethinyl estradiol plus desogestrel on premenstrual symptoms in Iranian women.

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    Abbas Norouzi Javidan

    2014-11-01

    Full Text Available Marvelon®, a combined oral contraceptive, contains 30 μg ethinyl estradiol (EE and 150 μg desogestrel (DE, and has been shown to be a well-tolerated and effective combination that provides high contraceptive reliability and good cycle control. However, its efficacy has not been yet evaluated among Iranian women. Thus, the study aimed to determine the effect of oral contraceptive pill on treating premenstrual symptoms and on various parameters associated with well-being and health in a sample of Iranian. This clinical trial (before- after study was performed at the family-planning clinic of the centers under the supervision of Tehran University of Medical Sciences on sixty-one women. The study protocol was approved by the Ethics Committee of Tehran University of Medical Sciences and all participants received a 21/7-day regimen of oral contraceptive containing 150 μg desogestrel (DE and 30 μg ethinyl estradiol (EE for six cycles. Efficacy parameters included changes in premenstrual symptoms were also assessed. Clinical data was collected by calendar of premenstrual experiences (COPE at baseline and treatment cycles 1,2, 3 and 6. Clinical variables were measured including low-density lipoprotein (LDL, high-density lipoprotein (HDL and triglyceride levels for two timing periods (baseline and last visit. Linear mixed model analyses were used to analyze differences in changes of the four factors of premenstrual syndrome (PMS, weight and blood pressure during these timing periods. The mean age of the women was 28.52 (SD=6.75 years. Participants on average had been pregnant 1.13 (SD=1.16 times. The linear mixed model analyses indicated that premenstrual syndrome symptoms reduced significantly over time (P0.05. A combined oral contraceptive containing ethinyl estradiol and desogestrel has a positive effect on women's health and reduces premenstrual symptoms.

  16. Premenstrual syndrome

    National Research Council Canada - National Science Library

    Kwan, Irene; Onwude, Joseph Loze

    2015-01-01

    A woman has premenstrual syndrome (PMS) if she complains of recurrent psychological and/or physical symptoms occurring during the luteal phase of the menstrual cycle, and often resolving by the end of menstruation...

  17. Prevalence of psychological and physical symptoms of pre-menstrual syndrome in female students

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    Awanish Kumar Pandey

    2013-01-01

    Full Text Available Pre-menstrual syndrome is a group of physical and psychological symptoms that appears before the menstrual bleeding. The study was designed to evaluate the prevalence of physical and psychological symptoms of pre-menstrual syndrome among female students of technical institution in Gorakhpur. Two hundred students aged between 15 to 30 years participated in the study and revealed that all the participants of study experienced at least 1 symptom of PMS. The most common physical symptom was joint\\muscle pain (77.5%. Lethargy (83% was reported as most common psychological symptom in the study. The study concluded that prevalence of PMS is 100%, and most of the participants (42.5% have more than 5 symptoms of PMS.

  18. Effect of Yoga Exercise on Premenstrual Symptoms among Female Employees in Taiwan

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    Su-Ying Tsai

    2016-07-01

    Full Text Available Yoga classes designed for women with premenstrual syndrome are available, but their efficacy is unclear. We investigated the effects of 12 weeks’ yoga exercise (yoga intervention on premenstrual symptoms in menstruating females in Taiwan. Sixty-four subjects completed the yoga intervention, and before and after the intervention filled out a structured self-report questionnaire about their demographics, personal lifestyle, menstrual status, baseline menstrual pain scores, premenstrual symptoms, and health-related quality of life. Of 64 subjects, 90.6% reported experiencing menstrual pain during menstruation. After the yoga intervention, subjects reported decreased use of analgesics during menstruation (p = 0.0290 and decreased moderate or severe effects of menstrual pain on work (p = 0.0011. The yoga exercise intervention was associated with the improvement of the scale of physical function (p = 0.0340 and bodily pain (p = 0.0087 of the SF-36, and significantly decreased abdominal swelling (p = 0.0011, breast tenderness (p = 0.0348, abdominal cramps (p = 0.0016, and cold sweats (p = 0.0143. Menstrual pain mitigation after yoga exercise correlated with improvement in six scales of the SF-36 (physical function, bodily pain, general health perception, vitality/energy, social function, mental health. Employers can educate female employees about the benefits of regular exercise such as yoga, which may decrease premenstrual distress and improve female employee health.

  19. Premenstrual Symptoms in Dysmenorrheic College Students: Prevalence and Relation to Vitamin D and Parathyroid Hormone Levels

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    Bayan A. Obeidat

    2012-11-01

    Full Text Available Objectives: To determine the prevalence of premenstrual symptoms (PMS due to primary dysmenorrhea among a sample of university female students, and to explore possible association with vitamin D and parathyroid (PTH levels, as well as frequency of consumption of dairy products. Design: A cross-sectional study. Setting: One Jordanian university. Subjects: A total of 177 female students aged between 18 and 24 years who experienced primary dysmenorrhea participated in the study and completed a self administered questionnaire to collect information concerning demographics, menstruation- related information, associated specified premenstrual symptoms, and consumption of dairy products. Plasma 25-hydroxyvitamin vitamin D level and intact parathyroid hormone level were measured. Results: Of the 177 participants 91.5% had two or more symptoms among which fatigue, mood swings, anxiety, abdominal bloating, and depression were the most prevalent symptoms. There was no evident association between presence of symptoms and vitamin D status, PTH level or dairy products consumption. Headaches and social withdrawal were significantly lower in those women who consumed high amounts of dairy products. Conclusion: Premenstrual symptoms are very common in young women with primary dysmenorrhea. PMS has no relation to levels of vitamin D, parathyroid hormone or dairy products consumption. Headache and social withdrawal may be affected by dairy product consumption.

  20. DO FOOT REFLEXOLOGY AND RELAXATION TRAINING DECREASE PREMENSTRUAL SYMPTOMS IN ADOLESCENT FEMALES

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    Marwa A. Mohamed

    2016-10-01

    Full Text Available Background: Premenstrual syndrome is a current condition characterized by troublesome symptoms as tension, irritability, depression, headache, anxiety and loss of self-control, so the aim of this study was to investigate the effect of foot reflexology augmented with relaxation training on premenstrual syndrome in adolescent females. Methods: A sample of 50 volunteers, virgin females diagnosed as premenstrual syndrome was selected from the students of Faculty of Physical Therapy, Cairo University. Their age was ranged between 19 to 23 years with mean value of (21.53±2.27 yrs and BMI was ≤28 Kg/m² with mean value of (24.04±2.41 Kg/m².A detailed medical history was obtained to screen other pathological conditions that may affect the results. Females were randomly assigned into two equal groups. Group (A consisted of 25 subjects who received foot reflexology in addition to relaxation training techniques twice a week for 8 weeks. Group (B consisted of 25 patients, who received relaxation training techniques only twice a week for 8 weeks. Assessment of all subjects in both groups was carried out before and after the treatment program through heart rate, respiratory rate in addition to plasma cortisol level and daily symptoms report chart. Results: Showed a statistical highly significant decrease (p<0.001 in heart rate, respiratory rate, plasma cortisol level as well as daily symptoms report score in group (A while there was a statistical significant decrease (p<0.05 in all variables in group (B. Conclusions: Adding foot reflexology to relaxation training had a great positive effect on premenstrual syndrome in adolescent females than relaxation training only.

  1. Association between Hardness (Difficulty of Chewing of the Habitual Diet and Premenstrual Symptoms in Young Japanese Women

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    Kentaro Murakami

    2010-01-01

    Full Text Available Recent evidence suggests that voluntary rhythmic movements such as chewing may increase blood serotonin and subsequently brain serotonin, which in turn acts to alleviate premenstrual symptoms. In this observational cross-sectional study, we tested the hypothesis that hardness (difficulty of chewing of the habitual diet (i.e. dietary hardness is associated with decreased premenstrual symptoms. Subjects were 640 female Japanese dietetic students aged 18–22 years. Dietary hardness was assessed as an estimate of masticatory muscle activity for the habitual diet (i.e. the difficulty of chewing the food. The consumption of a total of 107 foods was estimated by means of a self-administered, comprehensive diet history questionnaire, and masticatory muscle activity during the ingestion of these foods was estimated according to published equations. Menstrual cycle symptoms were assessed using the retrospective version of the Moos Menstrual Distress Questionnaire, from which total score and subscale scores (i.e. pain, concentration, behavioral change, autonomic reactions, water retention, and negative affect in the premenstrual phase were calculated and expressed as percentages relative to those in the intermenstrual phase. Dietary hardness was not associated with total score in the premenstrual phase (P for trend = 0.48. Further, no association was seen for any subscale score in the premenstrual phase (P for trend = 0.18–0.91. In conclusion, this preliminary study failed to substantiate a hypothesized inverse relationship between hardness of the habitual diet and premenstrual symptoms. Considering the plausibility of the putative mechanism, however, further investigation using more relevant measures of chewing and premenstrual symptoms is warranted.

  2. THE FREQUENCY OF SYMPTOMS OF THE PREMENSTRUAL SYNDROME BY ADOLESCENT FEMALES WITH HEARING IMPAIRMENT

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    Elvira Čekić

    2011-12-01

    Full Text Available The aim of this study was to determine among adolescent females with hearing impairment the frequency of symptoms of the premenstrual syndrome. The tested sample consisted of 62 adolescents with hearing impairment, and the control sample 62 “hearing” adolescents, the average age of 14-16 years in Sarajevo and Tuzla. Measuring instruments that were used Diagnostic and Statistical Manual of Mental Disorders (DSM IV. The most dominant symptoms of PMS established in this research are: emotional instability, anger and irritability, sensitivity in breast area, headache and depressed mood. The following frequency of symptoms was found: apparent emotional instability (100%, permanent and visible anger or irritability (90.32%, apparent anxiety, feeling of tension (77.41, reduced interest in usual activities (70.96%. There is no qualitative difference in the symptoms between adolescents with and without hearing impairment. There is a statistically signifcant difference in the prevalence of symptoms of the premenstrual syndrome in adolescents with hearing impairments compared to the control group adolescents.

  3. Attitudes toward menstruation, menstrual-related symptoms, and premenstrual syndrome among adolescent girls: a rural school-based survey.

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    Wong, Li Ping

    2011-06-21

    Folk culture surrounding menstrual-related matters has considerable implications for symptom expression and treatment-seeking behavior. A cross-sectional survey of 1,295 rural adolescent girls aged 13 to 19 years was conducted between February 4 and April 16, 2009 to examine these associations. With a higher score indicating a more positive attitude toward menstruation, the mean attitude score was 3.84 (SD ± 1.62) out of a maximum of six. No significant association was observed between the severity of menstrual symptoms and attitudes. Most (63.1%) of the participants identified themselves as having premenstrual symptoms, and 61.1% viewed premenstrual symptoms as a normal part of menstrual cycle. Participants with a higher severity of symptoms in the premenstrual (OR 1.05, 95% CI 1.01-1.10) and menstrual phase (OR 1.04, 95% CI 1.01-1.07), were more likely to consult a physician for premenstrual symptoms, and having a divorced/separated parents was associated with a reduced odds of consulting a physician compared to those having parents that were married (OR 0.19, 95% CI 0.05-0.83). The findings imply the need for education to help adolescent girls manage menstrual symptoms and increase awareness of the benefit of treating them. Given that menstrual-related information was widely available from mothers, family, and social culture are potentially important in shaping good menstrual attitudes.

  4. A Comparative Efficacy of Low-Dose Combined Oral Contraceptives Containing Desogestrel and Drospirenone in Premenstrual Symptoms

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    Jirath Wichianpitaya

    2013-01-01

    Full Text Available Objective. To compare the efficacy of low-dose COC containing desogestrel (DSG with drospirenone (DRSP in the changes of premenstrual symptoms. Methods. In an open-label randomized controlled trial, 90 women with premenstrual syndrome who required COC were randomly recruited and allocated equally to receive either 6 cycles of 20 micrograms ethinyl estradiol (EE/150 micrograms DSG (DSG group or 20 micrograms EE/3 mg DRSP (DRSP group in 24/4 extended regimen. Analysis of covariance and repeated analysis of variance were used to determine the difference of mean Women's Health Assessment Questionnaire (WHAQ scores changes between groups, within group, and in premenstrual, menstrual, and postmenstrual phases. Results. Baseline characteristics and WHAQ scores were comparable. At the ends of the 3rd and the 6th cycles, mean WHAQ scores of all the 3 phases in DRSP group showed significant reduction and were significantly lower than those in DSG group. DSG group showed significant reduction in both premenstrual and menstrual phases after the 6th cycle. Adverse effects were comparable in both groups. In conclusion, low-dose COC containing either DSG or DRSP reduced premenstrual symptoms, but the latter showed greater efficacy and earlier reduction.

  5. Frequency and severity of premenstrual symptoms in women taking birth control pills.

    Science.gov (United States)

    Yuk, V J; Cumming, C E; Fox, E E; Cumming, D C

    1991-01-01

    A retrospective study of a wide range of premenstrual symptomatology using the Premenstrual Assessment Form found little difference between women taking a low-dose birth control pill and non-pill-takers. These data are in keeping with older, but narrower, studies of women taking high-dose pills and raise questions about mechanisms of symptomatic and subclinical premenstrual changes.

  6. The Relationship of Premenstrual Syndrome Symptoms with Menstrual Attitude and Sleep Quality in Turkish Nursing Student

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    Özlem Aşcı

    2015-09-01

    Full Text Available Introduction: Symptoms induced by premenstrual syndrome (PMS adversely affect the women in reproduction period and decrease their quality of life. In literature, it is a common opinion thought that PMS could be associated with both sleep quality and menstrual attitudes. However, there has been no sufficient number of studies to define in what ways the PMS symptoms are correlated with sleep quality and menstrual attitudes. The objective of this study was to examine the relationship of PMS symptoms with menstrual attitude and sleep quality. Methods: The data were collected from 183 nursing students at Health School of Artvin Çoruh University by using a correlational design. Voluntary students completed a questionnaire involving socio-demographic characteristics, Premenstrual Syndrome Scale (PMSS, Menstrual Attitude Questionnaire (MAQ, and Pittsburgh Sleep Quality Index (PSQI. Results: Average age was 19.9 (1.8. The study determined a positively significant correlation between score of PMSS and mean scores of PSQI (r=0.306; P<0.001, and a negatively significant correlation between score of PMSS and total mean score of MAQ (r=-0.317; P<0.01. Similarly, multiple linear regression analysis showed that PSQI total score (​b=5.412; P<0.001 and MAQ total score (​ b=-27.455; P=0.001 significantly affected total score of PMSS.Conclusion: The intensity of PMS symptoms is associated with poor sleep quality and negative menstrual attitudes. Determining the methods of coping with PMS and strengthening the young girls on this subject may enhance their quality of future life.

  7. Epidemiological Distribution and Subtype Analysis of Premenstrual Dysphoric Disorder Syndromes and Symptoms Based on TCM Theories

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    Mingqi Qiao

    2017-01-01

    Full Text Available We performed an epidemiological investigation of subjects with premenstrual dysphoric disorder (PMDD to identify the clinical distribution of the major syndromes and symptoms. The pathogenesis of PMDD mainly involves the dysfunction of liver conveyance and dispersion. Excessive liver conveyance and dispersion are associated with liver-qi invasion syndrome, while insufficient liver conveyance and dispersion are expressed as liver-qi depression syndrome. Additionally, a nonconditional logistic regression was performed to analyze the symptomatic features of liver-qi invasion and liver-qi depression. As a result of this analysis, two subtypes of PMDD are proposed, namely, excessive liver conveyance and dispersion (liver-qi invasion syndrome and insufficient liver conveyance and dispersion (liver-qi depression syndrome. Our findings provide an epidemiological foundation for the clinical diagnosis and treatment of PMDD based on the identification of different types.

  8. The Effect of Relaxation and Positive Self-Talk on Symptoms of Premenstrual Syndrome

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    Kimiyaee Asadi

    2016-05-01

    Full Text Available Background Premenstrual syndrome (PMS is characterized by recurrent, moderate-to-severe affective, physical, and behavioral symptoms that develop during the luteal menstrual cycle and disappear within a few days of menstruation. Objectives This article aims to identify the effects of relaxation, positive self-talk, and a combination of relaxation and positive self-talk on premenstrual syndrome. Methods In this quasi-experimental study, 80 women with PMS disorder were selected using a simple random sampling method, in Hamadan, west of Iran. They were randomly divided into four groups. The first and second groups underwent positive self-talk and relaxation, respectively. The third group experienced positive self-talk and relaxation at the same time. The fourth group did not receive any treatment. The duration of treatment was 8 one-hour sessions. Data were collected using a PMS symptom severity questionnaire. All groups were followed up for six months after the intervention. Finally, data analysis was performed using SPSS version 18 for ANCOVA and Bonferroni tests. Results The results showed that compared to the control group, relaxation (23.2 and positive self-talk (21.25 treatment methods alone can reduce PMS (P < 0.001. On the other hand, a combined (relaxation + positive self-talk treatment method (13.75 was more effective in reducing PMS compared to relaxation or positive self-talk alone. Conclusions It seems that psychological therapy based on relaxation and positive self-talk can be significantly effective in reducing PMS.

  9. Comparing the Effects of Yoga & Oral Calcium Administration in Alleviating Symptoms of Premenstrual Syndrome in Medical Undergraduates

    OpenAIRE

    Mehta Bharati

    2016-01-01

    Introduction: Medical undergraduates are heavily burdened by their curriculum. The females, in addition, suffer from vivid affective or somatic premenstrual syndrome (PMS) symptoms such as bloating, mastalgia, insomnia, fatigue, mood swings, irritability, and depression. The present study was proposed to attenuate the symptoms of PMS by simple lifestyle measures like yoga and/or oral calcium. Methods: 65 medical female students (18-22 years) with a...

  10. Non-contraceptive oestrogen-containing preparations for controlling symptoms of premenstrual syndrome.

    Science.gov (United States)

    Naheed, Bushra; Kuiper, Jan Herman; Uthman, Olalekan A; O'Mahony, Fidelma; O'Brien, Patrick Michael Shaughn

    2017-03-03

    Premenstrual syndrome (PMS) is a psychological and somatic disorder of unknown aetiology, with symptoms typically including irritability, depression, mood swings, bloating, breast tenderness and sleep disturbances. About 3% to 10% of women who experience these symptoms may also meet criteria for premenstrual dysphoric disorder (PMDD). PMS symptoms recur during the luteal phase of the menstrual cycle and reduce by the end of menstruation. PMS results from ovulation and may be due to ovarian steroid interactions relating to neurotransmitter dysfunction. Premenstrual disorders have a devastating effect on women, their families and their work.Several treatment options have been suggested for PMS, including pharmacological and surgical interventions. The treatments thought to be most effective tend to fall into one of two categories: suppressing ovulation or correcting a speculated neuroendocrine anomaly.Transdermal oestradiol by patch, gel or implant effectively stops ovulation and the cyclical hormonal changes which produce the cyclical symptoms. These preparations are normally used for hormone therapy and contain lower doses of oestrogen than found in oral contraceptive pills. A shortened seven-day course of a progestogen is required each month for endometrial protection but can reproduce premenstrual syndrome-type symptoms in these women. To determine the effectiveness and safety of non-contraceptive oestrogen-containing preparations in the management of PMS. On 14 March 2016, we searched the following databases: the Cochrane Gynaecology and Fertility Group (CGF) Specialised Register; Cochrane Central Register of Studies (CRSO); MEDLINE; Embase; PsycINFO; CINAHL; ClinicalTrials.gov; metaRegister of Controlled trials (mRCT); and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) Search Portal. In addition, we checked the reference lists of articles retrieved. We included published and unpublished randomized placebo or active

  11. Effect of Combined Use of Calcium and Vitamin B6 on Premenstrual Syndrome Symptoms: a Randomized Clinical Trial

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    Seyedeh Zahra Masoumi

    2016-03-01

    Full Text Available Introduction: Premenstrual syndrome is one of the most common disorders in women, which includes a group of psychological and physical symptoms. The aim of this study was to examine the impact of combined use of calcium and vitamin B6 on premenstrual syndrome symptoms. Methods: This double blind randomized controlled was carried out on 76 students of Hamadan University of Medical Sciences. Students were randomly allocated to two groups. (38 people in each group. Student in intervention groups received calcium tablet (500mg and vitamin B6 (40 mg and student in intervention groups received only vitamin B6 twice a day for two consecutive months. The symptoms were assessed by Beck depression inventory (BDI and daily symptom records (DSR questionnaires. Analyses were carried out by test-retest method, Chi-square, Mann-Whitney, Independent t-test, and paired t-test using SPSS software ver.13. Results: The result showed that although the severity of symptoms decreased in both groups, but this reduction was more significant in the combined calcium and vitamin B6 group. Conclusion: According to the result, using of combination of calcium and vitamin B6 leads to better controlling of the premenstrual syndrome symptoms. Therefore it is recommended for women who suffer from these syndromes.

  12. Comparing the Effects of Yoga & Oral Calcium Administration in Alleviating Symptoms of Premenstrual Syndrome in Medical Undergraduates

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    Mehta Bharati

    2016-09-01

    Full Text Available Introduction: Medical undergraduates are heavily burdened by their curriculum. The females, in addition, suffer from vivid affective or somatic premenstrual syndrome (PMS symptoms such as bloating, mastalgia, insomnia, fatigue, mood swings, irritability, and depression. The present study was proposed to attenuate the symptoms of PMS by simple lifestyle measures like yoga and/or oral calcium. Methods: 65 medical female students (18-22 years with a regular menstrual cycle were asked to self-rate their symptoms, along with their severity, in a validated questionnaire for two consecutive menstrual cycles. Fifty-eight students were found to have PMS. Twenty girls were given yoga training (45 minutes daily, five days a week, for three months. Another group of 20 was given oral tablets of calcium carbonate daily (500 mg, for three months and rest 18 girl served as control group. Data were analyzed by SPSS ver.13 software. Results: The yoga and calcium groups showed a significant decrease in number and severity of premenstrual symptoms whereas in the control group there was not the significant difference. Conclusion: Encouraging a regular practice of yoga or taking a tablet of calcium daily in the medical schools can decrease the symptoms of premenstrual syndrome.

  13. Comparing the Effects of Yoga & Oral Calcium Administration in Alleviating Symptoms of Premenstrual Syndrome in Medical Undergraduates.

    Science.gov (United States)

    Bharati, Mehta

    2016-09-01

    Introduction: Medical undergraduates are heavily burdened by their curriculum. The females, in addition, suffer from vivid affective or somatic premenstrual syndrome (PMS) symptoms such as bloating, mastalgia, insomnia, fatigue, mood swings, irritability, and depression. The present study was proposed to attenuate the symptoms of PMS by simple lifestyle measures like yoga and/or oral calcium. Methods: 65 medical female students (18-22 years) with a regular menstrual cycle were asked to self-rate their symptoms, along with their severity, in a validated questionnaire for two consecutive menstrual cycles. Fifty-eight students were found to have PMS. Twenty girls were given yoga training (45 minutes daily, five days a week, for three months). Another group of 20 was given oral tablets of calcium carbonate daily (500 mg, for three months) and rest 18 girl served as control group. Data were analyzed by SPSS ver.13 software. Results: The yoga and calcium groups showed a significant decrease in number and severity of premenstrual symptoms whereas in the control group there was not the significant difference. Conclusion: Encouraging a regular practice of yoga or taking a tablet of calcium daily in the medical schools can decrease the symptoms of premenstrual syndrome.

  14. Premenstrual syndrome and premenstrual dysphoric disorder.

    Science.gov (United States)

    Biggs, Wendy S; Demuth, Robin H

    2011-10-15

    Premenstrual syndrome is defined as recurrent moderate psychological and physical symptoms that occur during the luteal phase of menses and resolve with menstruation. It affects 20 to 32 percent of premenopausal women. Women with premenstrual dysphoric disorder experience affective or somatic symptoms that cause severe dysfunction in social or occupational realms. The disorder affects 3 to 8 percent of premenopausal women. Proposed etiologies include increased sensitivity to normal cycling levels of estrogen and progesterone, increased aldosterone and plasma renin activity, and neurotransmitter abnormalities, particularly serotonin. The Daily Record of Severity of Problems is one tool with which women may self-report the presence and severity of premenstrual symptoms that correlate with the criteria for premenstrual dysphoric disorder in the Diagnostic and Statistical Manual of Mental Disorders, 4th ed., text revision. Symptom relief is the goal for treatment of premenstrual syndrome and premenstrual dysphoric disorder. There is limited evidence to support the use of calcium, vitamin D, and vitamin B6 supplementation, and insufficient evidence to support cognitive behavior therapy. Serotonergic antidepressants (citalopram, escitalopram, fluoxetine, sertraline, venlafaxine) are first-line pharmacologic therapy.

  15. The Effects of Melatonin on Menstrual Characteristics, Prolactin and Premenstrual Syndrome-Like Symptoms During a Simulated Eastward Deployment

    Science.gov (United States)

    1998-06-01

    the two. Plasma melatonin has been reported to be high in patients with hyperprolactinemia (Wetterberg, 1979). This is expected if melatonin controls...and mild hyperprolactinemia . Am.J.Obstet.Gvnecol. 168:854-861. Petrie, K., Conaglen, J.V., Thompson, L. and Chamberlain, K. 1989. Effect of melatonin

  16. Effect of menstrual cycle phase on glucose kinetics in healthy women & women with premenstrual symptoms.

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    Meena K. Nandimath

    2015-11-01

    Full Text Available Objective: To compare the blood glucose levels during the two phases of the menstrual cycle between healthy women and patients with premenstrual syndrome (PMS.Methods: From January of 2012 to the August of 2013, a descriptive cross-sectional study was performed among staff of tertiary care hospital.Inclusion Criteria: 1100 women aged 18 to 45 years, 2 Regular Menstrual cycle.Exclusion Criteria: 1 Menopause 2 Patient on Oral Contraceptive pills.After approval from IEC and informed consent from the 100 enrolled subjects with either the most severe symptoms of PMS or healthy controls. 2ml of venous blood was collected on fasting condition during the follicular phase (5-11 days of  menstrual cycleand the luteal phase of the cycle (19-28 days menstrual cycle and analyzed the serum concentrations of glucose by using the glucose oxidase method.Results: The statistical analysis was done using student's paired T test. P value less than 0.0001was taken as significant.No significant differences between the demographic data of the control and PMS groups were observed. The mean concentrations of glucose were significantly different during the follicular and luteal phases.

  17. Effects of Magnesium and Vitamin B6 on the Severity of Premenstrual Syndrome Symptoms

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    Elham Ebrahimi

    2012-11-01

    Full Text Available Introduction: The importance of resolving the problem of premenstrual syndrome for patients has been emphasized due to its direct and indirect economical effects on the society. The aim of the current study was to evaluate the effects of magnesium and vitamin B6 on the severity of premenstrual syndrome in patients referring to health centers affiliated to Isfahan University of Medical Sciences, Iran, during 2009-10. Methods: This two-stage double-blind clinical trial was conducted on 126 women who were randomly allocated into 3 groups to receive magnesium, vitamin B6, or placebo. The study was performed in 10 selected health centers in Isfahan and lasted for 4 months. To confirm premenstrual syndrome, the participants were asked to complete a menstrual diary for 2 months at home. Drug interventions were continued for two cycles and the results of before and after the intervention were compared. Results: The findings of this study showed that the mean scores of premenstrual syndrome significantly decreased after the intervention in all groups (p < 0.05. Conclusion: According to our findings, vitamin B6 and placebo had the most and least efficiency in improving the mean premenstrual syndrome score.

  18. Effectiveness of group cognitive-behavioral therapy ‎on ‎symptoms of premenstrual syndrome (PMS ‎

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    Maryam Maddineshat

    2016-02-01

    Full Text Available Objective: Standards of care and treatment of premenstrual syndrome (PMS vary. Non-drug ‎psychosocial intervention therapy is recommended for women with any kind of ‎discomfort or distress caused by PMS. The current study examined the effectiveness of ‎group cognitive-behavioral therapy on the symptoms of PMS at a girls’ dormitory of ‎North Khorasan University of Medical Sciences.Method: In this quasi-experimental study, 32 female students with PMS who were majoring in ‎nursing and midwifery and residing in the dormitory were selected using the ‎convenience sampling method and were assigned to experimental and control groups. ‎The Standardized Premenstrual Symptoms Screening Tool was used as the research ‎tool. Eight sessions of cognitive-behavioral group therapy were held for the studentsResults: There was a significant difference in psychological symptoms before and after ‎cognitive-behavioral therapy (p=0.012. Furthermore, cognitive-behavioral therapy was ‎effective on social interferences caused by PMS symptoms (p=0.012.‎Conclusion: Group cognitive-behavioral therapy effectively alleviates PMS symptoms in female ‎college students.‎

  19. Effect of Melissa officinalis Capsule on the Intensity of Premenstrual Syndrome Symptoms in High School Girl Students.

    Science.gov (United States)

    Akbarzadeh, Marzieh; Dehghani, Mansoore; Moshfeghy, Zeinab; Emamghoreishi, Masoumeh; Tavakoli, Pouran; Zare, Najaf

    2015-06-01

    Several studies are conducted on Premenstrual Syndrome (PMS). However, a few herbal surveys exist on the treatment of PMS in Iran. Due to the sedative effects of Melissa officinalis (M. officinalis), this question comes to mind that "can it be used in the treatment of PMS symptoms?" The current study aimed to assess the effect of M. officinalis capsule on the intensity of PMS in high-school girls. A double-blind randomized, placebo-controlled trial was performed on 100 high school girls from 2013 to 2014. The intervention group (n = 50) received 1200 mg of M. officinalis essence daily from the first to the last day of their menstrual cycle for three consecutive cycles. The second group (n = 50) received the placebo. The premenstrual symptoms screening tool was used to assess the intensity of PMS symptoms in the two groups before and one, two, and three months after the intervention. The data were analyzed using paired t-test and repeated measures analysis of variance. The results of repeated measures test revealed a significant reduction (P officinalis capsules were effective in reduction of the PMS symptoms. Yet, application of this medication requires further investigations.

  20. Women with Premenstrual Dysphoria Lack the Seemingly Normal Premenstrual Right-Sided Relative Dominance of 5-HTP-Derived Serotonergic Activity in the Dorsolateral Prefrontal Cortices - A Possible Cause of Disabling Mood Symptoms.

    Science.gov (United States)

    Eriksson, Olle; Wall, Anders; Olsson, Ulf; Marteinsdottir, Ina; Holstad, Maria; Ågren, Hans; Hartvig, Per; Långström, Bengt; Naessén, Tord

    2016-01-01

    To investigate potential quantitative and qualitative differences in brain serotonergic activity between women with Premenstrual Dysphoria (PMD) and asymptomatic controls. Serotonin-augmenting drugs alleviate premenstrual mood symptoms in the majority of women with PMD while serotonin-depleting diets worsen PMD symptoms, both indicating intrinsic differences in brain serotonergic activity in women with PMD compared to asymptomatic women. Positron-emission tomography with the immediate precursor of serotonin, 5-hydroxytryptophan (5-HTP), radiolabelled by 11C in the beta-3 position, was performed in the follicular and luteal phases for 12 women with PMD and 8 control women. Brain radioactivity-a proxy for serotonin precursor uptake and synthesis-was measured in 9 regions of interest (ROIs): the right and left sides of the medial prefrontal cortex, dorsolateral prefrontal cortex, putamen and caudate nucleus, and the single "whole brain". There were no significant quantitative differences in brain 5-HTP-derived activity between the groups in either of the menstrual phases for any of the 9 ROIs. However, multivariate analysis revealed a significant quantitative and qualitative difference between the groups. Asymptomatic control women showed a premenstrual right sided relative increase in dorsolateral prefrontal cortex 5-HTP derived activity, whereas PMD women displayed the opposite (p = 0.0001). Menstrual phase changes in this asymmetry (premenstrual-follicular) correlated with changes in self ratings of 'irritability' for the entire group (rs = -0.595, p = 0.006). The PMD group showed a strong inverse correlation between phase changes (premenstrual-follicular) in plasma levels of estradiol and phase changes in the laterality (dx/sin) of radiotracer activity in the dorsolateral prefrontal ROI (rs = -0.635; 0.027). The control group showed no such correlation. Absence of increased premenstrual right-sided relative 5-HTP-derived activity of the dorsolateral prefrontal

  1. Influence of Toxoplasma Gondii Infection on Symptoms and Signs of Premenstrual Syndrome: A Cross-sectional Study

    Science.gov (United States)

    Alvarado-Esquivel, Cosme; Sánchez-Anguiano, Luis Francisco; Hernández-Tinoco, Jesús; Pérez-Álamos, Alma Rosa; Rico-Almochantaf, Yazmin del Rosario; Estrada-Martínez, Sergio; Vaquera-Enriquez, Raquel; Díaz-Herrera, Arturo; Ramos-Nevarez, Agar; Sandoval-Carrillo, Ada Agustina; Salas-Pacheco, José Manuel; Cerrillo-Soto, Sandra Margarita; Antuna-Salcido, Elizabeth Irasema; Liesenfeld, Oliver; Guido-Arreola, Carlos Alberto

    2016-01-01

    Infection with Toxoplasma gondii in brain may cause some symptoms that resemble those in women with premenstrual syndrome. To determine the association of T. gondii infection with symptoms and signs of premenstrual syndrome, we examined 489 women aged 30–40 years old. Sera of participants were analyzed for the presence of anti-Toxoplasma IgG and IgM antibodies using enzyme-linked immunoassays (EIA) and T. gondii DNA by polymerase chain reaction (PCR). Anti-T. gondii IgG antibodies were found in 38 (7.8%) of the women studied. Anti-T. gondii IgM antibodies were found in 13 (34.2%) of the 38 IgG seropositive women. Logistic regression showed two variables associated with seropositivity to T. gondii: presence of diarrhea (odds ratio [OR] = 6.10; 95% confidence interval [CI]: 1.37–27.85; P = 0.01) and weight gain (OR = 2.89; 95% CI: 1.37–6.07; P = 0.005), and two variables associated with high (>150 IU/ml) levels of IgG against T. gondii: presence of diarrhea (OR = 7.40; 95% CI: 1.79–30.46; P = 0.006) and abdominal inflammation (OR = 3.38; 95% CI: 1.13–10.10; P = 0.02). Positivity to EIA IgG and PCR was positively associated with obesity and negatively associated with joint pain by bivariate analysis. Our study for the first time reveals a potential association of T. gondii infection with clinical manifestations of premenstrual syndrome. PMID:27980858

  2. Women with Premenstrual Dysphoria Lack the Seemingly Normal Premenstrual Right-Sided Relative Dominance of 5-HTP-Derived Serotonergic Activity in the Dorsolateral Prefrontal Cortices - A Possible Cause of Disabling Mood Symptoms

    DEFF Research Database (Denmark)

    Eriksson, Olle; Wall, Anders; Olsson, Ulf

    2016-01-01

    STUDY OBJECTIVE: To investigate potential quantitative and qualitative differences in brain serotonergic activity between women with Premenstrual Dysphoria (PMD) and asymptomatic controls. BACKGROUND: Serotonin-augmenting drugs alleviate premenstrual mood symptoms in the majority of women with PMD...... while serotonin-depleting diets worsen PMD symptoms, both indicating intrinsic differences in brain serotonergic activity in women with PMD compared to asymptomatic women. METHODS: Positron-emission tomography with the immediate precursor of serotonin, 5-hydroxytryptophan (5-HTP), radiolabelled by 11C...... in the beta-3 position, was performed in the follicular and luteal phases for 12 women with PMD and 8 control women. Brain radioactivity-a proxy for serotonin precursor uptake and synthesis-was measured in 9 regions of interest (ROIs): the right and left sides of the medial prefrontal cortex, dorsolateral...

  3. Validation of the Brazilian Portuguese version of the Premenstrual Symptoms Screening Tool (PSST and association of PSST scores with health-related quality of life

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    Rachel de A. Câmara

    Full Text Available Objective: To develop and validate a Brazilian Portuguese version of the Premenstrual Symptoms Screening Tool (PSST, a questionnaire used for the screening of premenstrual syndrome (PMS and of the most severe form of PMS, premenstrual dysphoric disorder (PMDD. The PSST also rates the impact of premenstrual symptoms on daily activities. Methods: A consecutive sample of 801 women aged ≥ 18 years completed the study protocol. The internal consistency, test-retest reliability, and content validity of the Brazilian PSST were determined. The independent association of a positive screen for PMS or PMDD and quality of life determined by the World Health Organization Quality of Life instrument-Abbreviated version (WHOQOL-Bref was also assessed. Results: Of 801 participants, 132 (16.5% had a positive screening for PMDD. The Brazilian PSST had adequate internal consistency (Cronbach’s alpha = 0.91 and test-retest reliability. The PSST also had adequate convergent/discriminant validity, without redundancy. Content validity ratio and content validity index were 0.61 and 0.94 respectively. Finally, a positive screen for PMS/PMDD was associated with worse WHOQOL-Bref scores. Conclusions: These findings suggest that PSST is a reliable and valid instrument to screen for PMS/PMDD in Brazilian women.

  4. Ways of coping with premenstrual change: development and validation of a premenstrual coping measure.

    Science.gov (United States)

    Read, Jennifer R; Perz, Janette; Ussher, Jane M

    2014-01-03

    Negative premenstrual change can result in distress for a significant proportion of women. Previous research has suggested that women employ a range of coping strategies and behaviours in order to manage and reduce premenstrual distress. However, as yet there has been no specific scale available to measure premenstrual coping. This research aimed to develop and validate a measure of premenstrual coping which can be used in future investigations of negative premenstrual experience. A sample of 250 women living in Australia, reporting mild to severe premenstrual distress, completed an online survey containing 64 items related to premenstrual coping. The items were generated by reviewing past literature related to premenstrual experience, in particular recent qualitative research on premenstrual coping. A principal components factor analysis with varimax rotation was conducted to determine item clusters that would form a measure. Reliability and validity were tested using calculations of Cronbach alphas, correlational analysis with psychological coping scales and a content analysis of participant reports of coping strategies. The factor analysis, which involved two principal component analyses, resulted in five factors containing 32 premenstrual coping behaviours. Interpretation of the factor solution drew on empirical and theoretical accounts of premenstrual coping and the emergent factors were labelled Avoiding Harm, Awareness and Acceptance of Premenstrual Change, Adjusting Energy, Self-Care, and Communicating. These factors form the subscales of the Premenstrual Coping Measure (PMCM). The subscales demonstrated acceptable to very good reliability and tests of construct, concurrent and content validity were supportive of sound validity. The PMCM provides a valid and reliable scale for quantifying ways of coping specific to negative premenstrual change. Conceptual similarity was found between some coping behaviours and behaviours positioned as symptoms of

  5. Comparison of the Effects of Relaxation and Vitamin B6 on Emotional and Physical Symptoms in Premenstrual Syndrome

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    Nahid Hasani

    2015-06-01

    Full Text Available Background: Premenstrual syndrome (PMS is consisted of multiple psychological and emotional symptoms. This disorder possesses adverse effects on women’ economic, social, familial and professional issues, therefore various medical therapies have been suggested, thus all have own side effects. Aim: To compare the effects of relaxation and vitamin B6 on emotional and physical symptoms of PMS. Method: This is a randomized clinical trial study with pre- and post-test design. The study was conducted on 150 girls living in public dormitory whom were randomly divided into three groups. The relaxation group trained in two sessions and then one week before menstruation, the taught techniques were carried out on a daily basis. The second group received 80mg vitamin B6 tablets QD for one week before menstruation and then three times a week for one cycle. The third group received no intervention as control group. Each day, data were collected using a researcher-made questionnaire and where analyzed using SPSS version 14 with paired T and ANOVA tests. Results: The mean age of the participants was 20.6±1.5 and their average weight was 54.1± 6.6. The mean scores of psychological symptoms after the interventionwere 1.2± 0.2 in vitamin B6 group, 0.3± 0.7 in relaxation group, and 1.6 ± 0.4 in the control group (p

  6. Seric ion level and its relationship with the symptoms of premenstrual syndrome in young women.

    Science.gov (United States)

    dos Santos, Larissa Almenara Silva; de Azeredo, Vilma Blondet; Eloy Chaves Barbosa, Diane; Augusta de Sá, Solange

    2013-11-01

    El objetivo del estudio fue evaluar el nivel de iones séricos y su relación con el síndrome premenstrual (PMS) Los síntomas en las mujeres jóvenes. Método: Noventa y tres voluntarios fueron monitoreados durante tres meses. La evaluación del estado nutricional se basa en el índice de masa corporal. Tres "mapas de síntomas diarios" se utilizaron para investigar la frecuencia de los síntomas de SPM. La evaluación bioquímica se realizó en el primer mes de la fase lútea. Los niveles de sodio, de potasio, de calcio, de magnesio se determinaron por métodos colorimétricos. La concentración de hemoglobina y hematocrito se determinaron por métodos convencionales. Resultados: Los síntomas como la ansiedad (1,13, 0,81, 0,66), edema (0,99, 0,51, 0,22 e), depresión (0,58, 0,36, 0,20) y la mastalgia (0,56; 0,35; 0,09) fueron los más evidentes en el ciclo menstrual de lútea y la fase folicular. Un pequeño número de voluntarios presentó hipocalemia (1,4%), hiponatremia (4,22%) y la hipernatremia (7,04%). Sin embargo, el mayor número de los voluntarios presentó menor nivel de calcio (83,09%). La frecuencia de las mujeres anémicas fue alta (24%). Se encontraron asociaciones significativas (P.

  7. PREMENSTRUAL SYNDROME SYMPTOMS (PMS AND PREVALENCE AMONG UNIVERSITY STUDENTS IN KARACHI, PAKISTAN

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    Zehra Sitwat

    2013-04-01

    Full Text Available A cross-sectional study was designed to investigate the frequency of PMS, on 520 subjects selected from University of Karachi (mean age 20±1.94.The PMS and menstrual cycle data of individuals were collected from prism calendar and symptom-thermal chart for three consecutive cycles. Based on the observations, all subjects were grouped as control (208 and PMS patients (312. The frequency (60% with symptoms include irritability (71.05%, fatigue (86.84%, and bowel constipation (36.76% and loose bowel (17.65%, appetite up (42.65%, and appetite down (51.47%.Breast tenderness (67.65%, abdominal blotting (47.06%, aggressiveness (29.41%, depression (13.24%, and insomnia (14.71%, labile mood (5.88%, and anger (7.35%. Elevated irritability and breast tenderness were observed in age group (19-24 years i.e. 92% and 82% respectively with p<0.001. The present study identified a pattern non-similar to the typical PMS pattern of the Western populations. The typical socio-cultural habitat of Pakistani population, may have led to the evolution of a different pattern of PMS.

  8. Patients with longstanding ulcerative colitis in remission do not have more irritable bowel syndrome-like symptoms than controls.

    Science.gov (United States)

    Lundgren, D; Rutegård, J; Eklöf, V; Palmqvist, R; Karling, P

    2016-11-24

    Irritable bowel syndrome (IBS) is more common in patients with ulcerative colitis (UC) than expected. The prevalence of IBS in patients with UC with longstanding disease is not known. We investigated the prevalence of IBS-like symptoms in patients with UC in remission and longstanding disease in comparison to control subjects. Sixty-eight patients with UC and 33 patients with hereditary familiar colon cancer and who underwent colonoscopy surveillance were included. Faecal calprotectin (FC), Gastrointestinal Symptoms Rating Scale-Irritable Bowel Syndrome (GSRS-IBS) and Hospital Anxiety and Depression scale were fulfilled prior to endoscopy. UC in remission was define by steroid-free clinical remission, a Mayo Score ≤ 1 on endoscopy, a FC ≤ 200 μg/g and no significant active inflammation on colon biopsies. Fifty-five UC patients met the criteria for being in remission. The median disease duration was 17 years. The patients with UC in remission tended to have lower scores on total GSRS-IBS score (6 vs 10.5; p = 0.062) and lower or equal scores on all specific IBS symptoms in comparison to controls. There was a moderate but significant correlation between diarrhoea scores and FC levels (in the span ≤ 200 μg/g) (rs 0.38; p = 0.004) in the UC in remission group. Patients with UC with longstanding disease and in remission do not have more IBS symptoms than controls. In UC patients in remission the FC level in the lower span showed a moderate correlation to symptoms of diarrhoea.

  9. Administration of Wasabia koreana Ameliorates Irritable Bowel Syndrome-Like Symptoms in a Zymosan-Induced Mouse Model.

    Science.gov (United States)

    Park, Bo-Kyung; Chun, Eunho; Choi, Jeong June; Shin, Younmin; Kho, Young Tak; Oh, Seung Hyun; Kim, Sun Yeou; Lee, Taek Hwan; Kim, Tae-Wan; Shin, Eunju; Do, Seon-Gil; Jin, Mirim

    2017-05-01

    Irritable bowel syndrome (IBS) is a functional gastrointestinal disease with complex pathophysiology involving the brain-gut axis. To assess the effects of Wasabia koreana (WK) on IBS, we employed a mouse model of colonic zymosan injection presenting with diarrhea-predominant IBS-like symptoms. Oral WK administration significantly diminished stool score, suppressed colon length and weight change, and minimized body weight loss without affecting food intake. In WK-treated mice, the submucosal thickening and epithelial lining of the colon were inhibited and were similar to those of naïve mice. Infiltration of mast cells into the colon and serum tumor necrosis factor-α levels were markedly suppressed. These effects were comparable to those of sulfasalazine, an anti-inflammatory drug. Furthermore, the number of visceral pain-related behaviors was significantly decreased, and locomotion activities measured in the elevated plus maze and open field tests were significantly increased by WK in a dose-dependent manner compared with amitriptyline, an antidepressant. These changes were accompanied by reduced FosB2 expression in the brain. Taken together, these data suggest that WK may have potential as a medicinal food for IBS by acting on inflammatory diarrhea and neural activity.

  10. Neuroticism-related personality traits are related to symptom severity in patients with premenstrual dysphoric disorder and to the serotonin transporter gene-linked polymorphism 5-HTTPLPR.

    Science.gov (United States)

    Gingnell, Malin; Comasco, Erika; Oreland, Lars; Fredrikson, Mats; Sundström-Poromaa, Inger

    2010-10-01

    Neuroticism has been linked to a functional polymorphism in the serotonin transporter gene (5-HTTLPR), with short-allele carriers being overrepresented among high-scorers on neuroticism. Studies evaluating neuroticism-related personality traits in relation to the 5-HTTLPR polymorphism among patients with premenstrual dysphoric disorder (PMDD) and are lacking. The primary aim of this study was to evaluate the relationship between PMDD and neuroticism-related personality traits, and secondly, to relate the personality trait scores of PMDD patients to experienced symptom severity and to the 5-HTTLPR short allele. Thirty PMDD patients and 55 asymptomatic healthy controls were included in the study. The Swedish Universities Scale of Personality was used to evaluate personality traits. Genotype analyses were available in 27 PMDD patients and 18 healthy controls. Women with PMDD displayed higher levels of neuroticism-related personality traits (psychic trait anxiety, somatic trait anxiety, embitterment, stress susceptibility and mistrust) than healthy controls, and these effects were most prominent in women with more severe luteal phase symptoms. Furthermore, PMDD patients with at least one copy of the short allele of the 5-HTTLPR polymorphism scored higher on psychic trait anxiety and lack of assertiveness than PMDD patients who were homozygous for the long allele. PMDD patients who suffer from more severe luteal phase symptoms also display increased scores of neuroticism-related personality traits in comparison with healthy controls. Within the group of PMDD patients, differences in certain personality trait scores are associated with the short allele of the 5-HTTLPR polymorphism.

  11. Effect of Taking Soybean Supplement and Regular Aerobic Exercise in Water on Mental and Physical Symptoms of Premenstrual Syndrome among Female Students

    Directory of Open Access Journals (Sweden)

    Masume Nazemi

    2014-04-01

    Full Text Available Introduction: The purpose of this study was to investigate the effect of taking soybean supplement and regular aerobic exercise in water on mental and physical symptoms of premenstrual syndrome (PMS among female students. Methods: This study was a single blind quasi-experimental trial that was conducted on female students living in dormitories of Shahroud University. In this study of 67 female students suffering from severe PMS that were eligible for inclusion, 40 persons voluntarily by completing a consent form were willing to work with us until the end of the study. After performing the pre-test and completing the questionnaire (PMS, subjects were divided into 4 groups: Aerobic training, taking soybean supplement, soybean supplement along with aerobic exercise and placebo. Aerobic exercises include activities in water for 8 weeks, with three sessions per week, and intensity of 55 to 65 percent of maximum heart rate. The supplement contains a capsule of 500 mg of soybean, taken once daily and the placebo contains starch, flour and oleaster powder that was similar to soybean capsule, taken once daily. At the end of eight weeks in the post-test stage, participants again completed the PMS questionnaire accurately. Given the normality of data, two-way ANOVA was performed to analyze the data using SPSS18 software. Results: The results showed that aerobic training in water for eight weeks had a significantly effect on general, physical and mental PMS symptoms in training group. Moreover, taking soybean for eight weeks had a significant effect on general and mental symptoms in supplement group, but no significant effect was observed in physical symptoms. In addition, 8 weeks of taking soybean supplement along with aerobic exercise in the water reduce the symptoms, but this difference was not significant. Conclusion: According to the results of this research, Soybean supplement or aerobic exercise in water can be used to treat or reduce PMS symptoms.

  12. Clinical Profiles of Premenstrual Experiences Among Women Having Premenstrual Syndrome (PMS): Affective Changes Predominate and Relate to Social and Occupational Functioning.

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    Schmelzer, Katarina; Ditzen, Beate; Weise, Cornelia; Andersson, Gerhard; Hiller, Wolfgang; Kleinstäuber, Maria

    2015-01-01

    Our objective for this study was to examine symptom severity among women suffering from premenstrual syndrome as well as associations between symptom severity and impairment. In a one-cycle prospective study, various premenstrual symptoms of 91 women were assessed. Tension and irritability were the most severe symptoms. Headache, irritability, self-deprecating thoughts, and depressed mood were the symptoms that were subjectively rated as the most burdensome. Significant correlations were found between the mean premenstrual severity and functional impairment. The severity of premenstrual affective symptoms was related to social impairment. The severity of psychological symptoms was correlated with occupational impairment. These findings confirm the prominent role of premenstrual affective symptoms and support classification guidelines focusing on both affective and physical changes.

  13. [Psychiatric and psychological aspects of premenstrual syndrome].

    Science.gov (United States)

    Limosin, F; Ades, J

    2001-01-01

    Numerous, but heterogeneous studies have been performed about premenstrual syndrome, with finally a lack of credibility and interest among practitioners. More recently with the diagnosis criteria generalization, psychiatrists were more concerned about this syndrome, because of anxiety and mood symptoms involved in social impairment and need of medical care. In 1983 in the United States, the National Institute of Mental Health conference devoted to this topic proposed the first diagnosis criteria, requiring a prospective and daily assessment of the symptoms. In 1987, the American Psychiatric Association, in the DSM III-R, introduced the Late Luteal Phase Dysphoric Disorder diagnosis that became in 1994 in the DSM IV the Premenstrual Dysphoric Disorder, with the same diagnosis criteria. In the literature, prevalence rates are very heterogeneous according to the diagnosis criteria used and to the populations studied. One of the most relevant criteria is the induced impairment, such as avoidance of social activities, or search for medical care. Lifetime prevalence is thus estimated between 75 and 85% if considering the report of one or several symptoms, between 10 and 15% in case of medical care request, and between 2 and 5% in case of social activities interruption. To distinguish isolated complaints from a disabling disorder, self-questionnaires are the best way of assessment in a so complex and changing disease. Most of the epidemiological studies found a positive correlation between the premenstrual dysphoric symptoms and the lifetime major depressive disorder diagnosis. However, recent prospective studies failed to find an association between premenstrual syndrome and an increased risk of major depression. On the other hand, some studies showed that the premenstrual period is a risk period for associated psychiatric disorders exacerbations, as the obsessive-compulsive disorder, more severe alcohol intakes in case of alcoholism, symptoms increase in schizophrenics

  14. Premenstrual syndrome: a psychological overview.

    Science.gov (United States)

    Riven, L

    1983-10-01

    This paper reviews the premenstrual syndrome (PMS) from a historical and psychological perspective. The physician must recognize that the premenstruum-the four days before the onset of the menses-is a `high risk' phase for women. They may demonstrate somatic and psychological complaints such as irritability, aggression, tension, anxiety, depression, lethargy, insomnia, poor coordination and concentration. Psychological disturbances can range from self-deprecation and the feeling that `everything is too much' to pronounced feelings of oppression and depression. Psychiatric patients may become even more disturbed at this time. Recent reviews on PMS have studied its etiology and its possible connection to hormone imbalance, but to date there is no complete explanation for the syndrome's psychological symptoms. The most promising treatments for the psychological symptoms of PMS are pyridoxine (although there are conflicting reports about it), antidepressants, benzodiazepines if anxiety and tension dominate, and ongoing psychotherapy for severe cases.

  15. Premenstrual Distress Among Japanese High School Students: Self-Care Strategies and Associated Physical and Psychosocial Factors.

    Science.gov (United States)

    Otsuka-Ono, Hiroko; Sato, Iori; Ikeda, Mari; Kamibeppu, Kiyoko

    2015-01-01

    This study aimed to identify self-care strategies and assess physical and psychosocial factors associated with premenstrual distress among high school students. A cross-sectional survey of 217 adolescent girls aged 15 to 18 years was conducted in October 2009. Most (84.3 percent) had at least one or more symptoms of premenstrual distress. Premenstrual distress interfered with normal school activity in 51.2 percent. Most participants (57.1 percent) did not perform any self-care strategies for premenstrual distress. A hierarchical multiple linear regression analysis was conducted. Comprehension of one's own physical and mental states during premenstrual phases mediated the relationship between neuroticism and premenstrual distress. Activity restrictions due to menstrual distress mediated the relationship between the family's understanding of one's behavior during premenstrual phases and premenstrual distress. Findings suggest that, even if girls have neuroticism, it will be important to teach them to address the comprehension of one's own physical and mental states so that perceptions of both premenstruation and menstruation become more positive. Findings also suggest that the family's understanding was associated with alleviation of premenstrual distress. This study suggests the need for education to help adolescent girls and their families manage premenstrual distress and increase awareness of the benefit of managing its associated symptoms.

  16. Effects of qigong exercise on fatigue, anxiety, and depressive symptoms of patients with chronic fatigue syndrome-like illness: a randomized controlled trial.

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    Chan, Jessie S M; Ho, Rainbow T H; Wang, Chong-Wen; Yuen, Lai Ping; Sham, Jonathan S T; Chan, Cecilia L W

    2013-01-01

    Background. Anxiety/depressive symptoms are common in patients with chronic fatigue syndrome- (CFS-) like illness. Qigong as a modality of complementary and alternative therapy has been increasingly applied by patients with chronic illnesses, but little is known about the effect of Qigong on anxiety/depressive symptoms of the patients with CFS-like illness. Purpose. To investigate the effects of Qigong on fatigue, anxiety, and depressive symptoms in patients with CFS-illness. Methods. One hundred and thirty-seven participants who met the diagnostic criteria for CFS-like illness were randomly assigned to either an intervention group or a waitlist control group. Participants in the intervention group received 10 sessions of Qigong training twice a week for 5 consecutive weeks, followed by home-based practice for 12 weeks. Fatigue, anxiety, and depressive symptoms were assessed at baseline and postintervention. Results. Total fatigue score [F(1,135) = 13.888, P Qigong group compared to controls. The anxiety score was not significantly improved in the Qigong group. Conclusion. Qigong may not only reduce the fatigue symptoms, but also has antidepressive effect for patients with CFS-like illness. Trial registration HKCTR-1200.

  17. Effects of Qigong Exercise on Fatigue, Anxiety, and Depressive Symptoms of Patients with Chronic Fatigue Syndrome-Like Illness: A Randomized Controlled Trial

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    Jessie S. M. Chan

    2013-01-01

    Full Text Available Background. Anxiety/depressive symptoms are common in patients with chronic fatigue syndrome- (CFS- like illness. Qigong as a modality of complementary and alternative therapy has been increasingly applied by patients with chronic illnesses, but little is known about the effect of Qigong on anxiety/depressive symptoms of the patients with CFS-like illness. Purpose. To investigate the effects of Qigong on fatigue, anxiety, and depressive symptoms in patients with CFS-illness. Methods. One hundred and thirty-seven participants who met the diagnostic criteria for CFS-like illness were randomly assigned to either an intervention group or a waitlist control group. Participants in the intervention group received 10 sessions of Qigong training twice a week for 5 consecutive weeks, followed by home-based practice for 12 weeks. Fatigue, anxiety, and depressive symptoms were assessed at baseline and postintervention. Results. Total fatigue score [F1,135=13.888, P<0.001], physical fatigue score [F1,135=20.852, P<0.001] and depression score [F1,135=9.918, P=0.002] were significantly improved and mental fatigue score [F1,135=3.902, P=0.050] was marginally significantly improved in the Qigong group compared to controls. The anxiety score was not significantly improved in the Qigong group. Conclusion. Qigong may not only reduce the fatigue symptoms, but also has antidepressive effect for patients with CFS-like illness. Trial registration HKCTR-1200.

  18. Caffeine-containing beverages, total fluid consumption, and premenstrual syndrome.

    Science.gov (United States)

    Rossignol, A M; Bonnlander, H

    1990-09-01

    The main objective of this study was to evaluate whether daily consumption of caffeine-containing beverages is related to the prevalence and severity of premenstrual syndrome apart from any effects of daily total fluid consumption. A secondary objective was to determine whether daily total fluid consumption itself is related to premenstrual syndrome. The study is based on 841 responses to a questionnaire probing menstrual and premenstrual health, and daily fluid consumption, which was mailed to female university students in Oregon. Analysis of the data revealed that consumption of caffeine-containing beverages was strongly related to the prevalence of premenstrual syndrome. Among women with more severe symptoms, the relation between consumption of caffeine-containing beverages and premenstrual syndrome was dose-dependent, with prevalence odds ratios equal to 1.3 for consumers of one cup of a caffeine-containing beverage per day and increasing steadily to 7.0 for consumers of eight to 10 cups per day. The effects were apparent among both caffeine-containing tea/coffee consumers and caffeine-containing soda consumers. The observed effects were only slightly reduced when daily total fluid consumption was controlled. Daily total fluid consumption also was related to the prevalence of premenstrual symptoms although the effects were large only for consumers of 13-19 cups of fluid per day (the largest amount studied).

  19. Qigong exercise alleviates fatigue, anxiety, and depressive symptoms, improves sleep quality, and shortens sleep latency in persons with chronic fatigue syndrome-like illness.

    Science.gov (United States)

    Chan, Jessie S M; Ho, Rainbow T H; Chung, Ka-Fai; Wang, Chong-Wen; Yao, Tzy-Jyun; Ng, Siu-Man; Chan, Cecilia L W

    2014-01-01

    Objectives. To evaluate the effectiveness of Baduanjin Qigong exercise on sleep, fatigue, anxiety, and depressive symptoms in chronic fatigue syndrome- (CFS-) like illness and to determine the dose-response relationship. Methods. One hundred fifty participants with CFS-like illness (mean age = 39.0, SD = 7.9) were randomly assigned to Qigong and waitlist. Sixteen 1.5-hour Qigong lessons were arranged over 9 consecutive weeks. Pittsburgh Sleep Quality Index (PSQI), Chalder Fatigue Scale (ChFS), and Hospital Anxiety and Depression Scale (HADS) were assessed at baseline, immediate posttreatment, and 3-month posttreatment. The amount of Qigong self-practice was assessed by self-report. Results. Repeated measures analyses of covariance showed a marginally nonsignificant (P = 0.064) group by time interaction in the PSQI total score, but it was significant for the "subjective sleep quality" and "sleep latency" items, favoring Qigong exercise. Improvement in "subjective sleep quality" was maintained at 3-month posttreatment. Significant group by time interaction was also detected for the ChFS and HADS anxiety and depression scores. The number of Qigong lessons attended and the amount of Qigong self-practice were significantly associated with sleep, fatigue, anxiety, and depressive symptom improvement. Conclusion. Baduanjin Qigong was an efficacious and acceptable treatment for sleep disturbance in CFS-like illness. This trial is registered with Hong Kong Clinical Trial Register: HKCTR-1380.

  20. Qigong Exercise Alleviates Fatigue, Anxiety, and Depressive Symptoms, Improves Sleep Quality, and Shortens Sleep Latency in Persons with Chronic Fatigue Syndrome-Like Illness

    Directory of Open Access Journals (Sweden)

    Jessie S. M. Chan

    2014-01-01

    Full Text Available Objectives. To evaluate the effectiveness of Baduanjin Qigong exercise on sleep, fatigue, anxiety, and depressive symptoms in chronic fatigue syndrome- (CFS- like illness and to determine the dose-response relationship. Methods. One hundred fifty participants with CFS-like illness (mean age = 39.0, SD = 7.9 were randomly assigned to Qigong and waitlist. Sixteen 1.5-hour Qigong lessons were arranged over 9 consecutive weeks. Pittsburgh Sleep Quality Index (PSQI, Chalder Fatigue Scale (ChFS, and Hospital Anxiety and Depression Scale (HADS were assessed at baseline, immediate posttreatment, and 3-month posttreatment. The amount of Qigong self-practice was assessed by self-report. Results. Repeated measures analyses of covariance showed a marginally nonsignificant (P= 0.064 group by time interaction in the PSQI total score, but it was significant for the “subjective sleep quality” and “sleep latency” items, favoring Qigong exercise. Improvement in “subjective sleep quality” was maintained at 3-month posttreatment. Significant group by time interaction was also detected for the ChFS and HADS anxiety and depression scores. The number of Qigong lessons attended and the amount of Qigong self-practice were significantly associated with sleep, fatigue, anxiety, and depressive symptom improvement. Conclusion. Baduanjin Qigong was an efficacious and acceptable treatment for sleep disturbance in CFS-like illness. This trial is registered with Hong Kong Clinical Trial Register: HKCTR-1380.

  1. Drenagem linfática manual nos sintomas da síndrome pré-menstrual: estudo piloto Manual lymphatic drainage for premenstrual syndrome symptoms: a pilot study

    Directory of Open Access Journals (Sweden)

    Juliana de Jesus Ferreira

    2010-03-01

    Full Text Available A síndrome pré-menstrual é um complexo de sintomas - dentre os quais o edema pré-menstrual - entre o 10o e o 14o dias que antecedem a menstruação e cessam no início do fluxo menstrual. A técnica de drenagem linfática manual (DLM drena o excesso de líquido acumulado, atua no edema e poderia aliviar esses sintomas. O objetivo deste estudo piloto foi verificar o efeito da DLM no alívio dos sintomas da síndrome pré-menstrual e a qualidade de vida relacionada à saúde em quatro mulheres jovens. O estudo foi realizado ao longo de dois ciclos menstruais, ciclo 1 sem intervenção terapêutica, e o segundo ciclo, com aplicação da técnica de DLM. As participantes foram avaliadas, no início do ciclo 1 e final do ciclo 2, por anamnese, mensuração de estatura e massa, estimativa da composição corporal, diário de sintomas e quanto à qualidade de vida relacionada à saúde, pelo WHOQoL-bref. Os resultados mostraram redução significativa apenas do diâmetro de abdome superior nos níveis xifóide e umbilical; as médias total e individual dos sintomas do diário reduziram-se, porém sem significância, tal como ocorreu no aumento dos escores no WHOQoL-bref. A drenagem linfática manual foi eficaz na diminuição de um sintoma da síndrome pré-menstrual, o edema em região superior abdominal, e não alterou a qualidade de vida dessas jovens.Premenstrual syndrome is a symptomatology - including premenstrual edema - that affects women between the 10th and 14th days prior to menstruation and ends at the onset of menstrual flux. The technique of manual lymphatic drainage (MLD draws off accumulated fluid excess, acts on edema and might help relieve such symptoms. The purpose of this pilot study was to assess the effect of MLD on premenstrual symptoms and on health-related quality of life of four young women. The study was carried out along two menstrual cycles, the first with no intervention; MLD was applied along the second cycle

  2. Analysis of Symptoms Related to Edema of Premenstrual Dysphoric Disorder and Their Pathogenesis%经前烦躁症水肿相关症状及其病机分析

    Institute of Scientific and Technical Information of China (English)

    孙飞; 王海军; 乔明琦; 张惠云; 孙文君; 辛荣荣

    2015-01-01

    Objective:To explore symptomatologic characteristics of edema of premenstrual dysphoric disorder (PMDD) and the pathogenesis of relative symptoms by analyzing symptomatologic characteristics of PMDD,so as to provide reference for clinical syndrome differentiation. Method:An epidemiological investigation on PMDD was carried out by 6 institutions of our country. The premenstrual symtoms of the subjects were ob-served. Symptoms and signs closely related to edema were selected by unconditioned logistic regression anal ysis. Result:In the 675 patients with PMDD,536(79.5%) were without edema and 138(20.5%) had edema symptoms. Symptoms closely related to edema of PMDD mainly include intolerance of cold,cold limbs,dis-tention in head,breast pain,abdominal bearing-down pain,loose stool,chest congestion,fatigue,enlarged tongue and so on. Conclusion:As one of the symptoms of PMDD,edema and other closely related symptoms reflect-ed the basic pathogenesis of PMDD were dampness obstruction caused by spleen deficiency and disorder and stagnation of liver qi.%目的:结合经前烦躁症(PMDD)症状学特点,探讨PMDD水肿症状学特点及相关症状的发病机制,为临床辨证提供依据。方法:全国六家单位联合进行PMDD流行病学调查,观察受试者月经前症状,采用有非条件logistic回归分析筛选出与水肿密切相关的症状体征。结果:675例PMDD 患者中,无水肿536例,为总病例数的79.5%,水肿症状者138例,为总病例数的20.5%。与PMDD水肿症状关联密切的症状主要为畏寒肢冷、头胀、乳房胀痛、小腹坠胀、便溏、胸闷、疲劳、舌胖大等。结论:通过分析认为,水肿作为PMDD症状之一,与其密切相关的其他症状体征均反映出其基本病机为脾虚湿停,肝气郁滞逆乱。

  3. The Cerebellum and Premenstrual Dysphoric Disorder

    Science.gov (United States)

    Rapkin, Andrea J.; Berman, Steven M.; London, Edythe D.

    2017-01-01

    The cerebellum constitutes ten percent of brain volume and contains the majority of brain neurons. Although it was historically viewed primarily as processing motoric computations, current evidence supports a more comprehensive role, where cerebro-cerebellar feedback loops also modulate various forms of cognitive and affective processing. Here we present evidence for a role of the cerebellum in premenstrual dysphoric disorder (PMDD), which is characterized by severe negative mood symptoms during the luteal phase of the menstrual cycle. Although a link between menstruation and cyclical dysphoria has long been recognized, neuroscientific investigations of this common disorder have only recently been explored. This article reviews functional and structural brain imaging studies of PMDD and the similar but less well defined condition of premenstrual syndrome (PMS). The most consistent findings are that women with premenstrual dysphoria exhibit greater relative activity than other women in the dorsolateral prefrontal cortex and posterior lobules VI and VII of the neocerebellum. Since both brain areas have been implicated in emotional processing and mood disorders, working memory and executive functions, this greater activity probably represents coactivation within a cerebro-cerebellar feedback loop regulating emotional and cognitive processing. Some of the evidence suggests that increased activity within this circuit may preserve cerebellar structure during aging, and possible mechanisms and implications of this finding are discussed.

  4. PMS as a process of negotiation: women's experience and management of premenstrual distress.

    Science.gov (United States)

    Ussher, Jane M; Perz, Janette

    2013-01-01

    The absence of reports of premenstrual syndrome (PMS) in contexts such as China, Hong Kong, and India has led to the conclusion that PMS is a culture-bound syndrome. This qualitative study examines whether is it possible for women in a Western cultural context to negotiate negative premenstrual change in order to effectively avoid or reduce premenstrual distress. Sixty women who self-defined as a 'PMS sufferer' took part in one-to-one interviews, which were analysed using theoretical thematic analysis from a material-discursive-intrapsychic (MDI) perspective. Three major themes were consistently identified across relationship type and context, reflecting women's strategies of premenstrual self-regulation and coping: 'Self-monitoring and awareness: recognition and acceptance of premenstrual change'; 'Coping through self-regulation of premenstrual distress', including: 'avoidance of stress and conflict', 'escaping relational demands and responsibilities', and 'care of the self'; and 'Coping as an inter-subjective experience'. These findings challenge the view of PMS as a fixed unitary syndrome, suggesting that premenstrual change is an ongoing process of negotiation, in which women are agentic subjects, not passive 'PMS sufferers'. This has implications for therapists working with women reporting moderate-severe PMS, suggesting that the reframing of 'symptoms' as normal change, behavioural coping strategies, and self-monitoring, can effectively reduce premenstrual distress.

  5. Fulfillment of the premenstrual dysphoric disorder criteria confirmed using a self-rating questionnaire among Japanese women with depressive disorders

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    Kametani Machiko

    2011-05-01

    Full Text Available Abstract Background Some women with depressive disorders experience severe premenstrual symptoms. However, there have been few studies in which premenstrual symptoms in women suffering from depressive disorders were assessed. In this study, we aimed to investigate premenstrual symptoms in women with depressive disorders using the premenstrual dysphoric disorder (PMDD scale. Methods We administered questionnaires to 65 Japanese female outpatients who had been diagnosed with a major depressive disorder or dysthymic disorder and to 303 healthy women as control subjects. The questionnaire consisted of items on demographics and the PMDD scale, which was modified from the premenstrual symptoms screening tool (PSST developed by Steiner et al. (Arch Womens Ment Health 2003, 6:203-209. Results Twenty-eight women (43.1% with depressive disorder fulfilled certain items of the PMDD scale. These women are considered to have coexisting PMDD and a depressive disorder, or to have premenstrual exacerbation (PME of a depressive disorder. On the other hand, 18 women (5.9% in the control group were diagnosed as having PMDD. The depressive disorder group who fulfilled the PMDD criteria had more knowledge of the term premenstrual syndrome (PMS and took more actions to attenuate premenstrual symptoms than the control group with PMDD. Conclusions Our findings demonstrated that the occurrence of severe premenstrual symptoms is much higher in women with depressive disorders than in healthy subjects. This is partially due to this group containing women with PME, but mainly due to it containing women with PMDD. The higher percentage of PMDD suggests similarity between PMDD and other depressive disorders. Furthermore, educating healthy Japanese women and women with depressive disorders about premenstrual symptoms and evidence-based treatment for them is necessary.

  6. Relationship of premenstrual syndrome and premenstrual dysphoric disorder with major depression: Relevance to clinical practice

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    Susanta Kumar Padhy

    2015-01-01

    Full Text Available Background: Premenstrual syndrome (PMS, premenstrual dysphoric disorder (PMDD and depressive disorder are fairly common; symptoms do overlap, often under-identified and under-emphasized, particularly in rural India. Objective: The objective was to assess the occurrence of PMS and PMDD in a sample of students and staff of a nursing college and to find their correlation with depression. Materials and Methods: A prospective cohort study; Tertiary Care Hospital in Rural India (Wardha, Maharashtra; 118 female nursing students or staff aged between 18 and 40 years, who were likely to stay within the institution for the study period. The participants were rated on Penn daily symptom report prospectively for a period of 3-month. Those who scored positive were applied diagnostic and statistical manual of mental disorders, 4 th edition, text revision (DSM-IV TR criteria for PMDD; and were applied primary care evaluation of mental disorders depression screening followed by DSM-IV TR criteria for depression. Severity of depression was measured using Hamilton Depression Rating Scale. Results: Main outcome measures were frequency and severity of depression in individuals with PMS and PMDD and their clinical and sociodemographic correlation. The age range of the sample was 18-37 years. Some PMS symptoms were observed in 67%; diagnosis of PMDD in 10%; depressive symptoms in 28% of the sample. 46.4% of those with depressive symptoms had major depression. The diagnosis of major depression was significantly associated with the severity of PMS symptoms as well as the presence of PMDD. Conclusion: Premenstrual syndrome is present in a substantial proportion of young females. Concurrent depression is increased by the severity of PMS symptoms and the presence of PMDD. Gynecologist needs to screen such subjects for depression and refer to mental-health professional early, in routine clinical practice.

  7. Prescribing patterns in premenstrual syndrome

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    Jones Paul W

    2002-06-01

    Full Text Available Abstract Background Over 300 therapies have been proposed for premenstrual syndrome. To date there has been only one survey conducted in the UK of PMS treatments prescribed by GPs, a questionnaire-based study by the National Association of Premenstrual Syndrome in 1989. Since then, selective serotonin re-uptake inhibitors have been licensed for severe PMS/PMDD, and governmental recommendations to reduce the dosage of vitamin B6 (the first choice over-the-counter treatment for many women with PMS have been made. This study investigates the annual rates of diagnoses and prescribing patterns for premenstrual syndrome (1993–1998 within a computerised general practitioner database. Methods Retrospective survey of prescribing data for premenstrual syndrome between 1993–1998 using the General Practice Research Database for the West Midlands Region which contains information on 282,600 female patients Results Overall the proportion of women with a prescription-linked diagnosis of premenstrual syndrome has halved over the five years. Progestogens including progesterone were the most commonly recorded treatment for premenstrual syndrome during the whole study period accounting for over 40% of all prescriptions. Selective serotonin-reuptake inhibitors accounted for only 2% of the prescriptions in 1993 but rose to over 16% by 1998, becoming the second most commonly recorded treatment. Vitamin B6 accounted for 22% of the prescriptions in 1993 but dropped markedly between 1997 and 1998 to 11%. Conclusions This study shows a yearly decrease in the number of prescriptions linked to diagnoses for premenstrual syndrome. Progestogens including progesterone, is the most widely prescribed treatment for premenstrual syndrome despite the lack of evidence demonstrating their efficacy.

  8. OBSERVATION ON THE THERAPEUTIC EFFECT OF ACUPUNCTURE THERAPY FOR SIMPLE OBESITY COMPLICATED WITH PREMENSTRUAL TENSION SYNDROME

    Institute of Scientific and Technical Information of China (English)

    LIU Zhi-cheng; LU Ya-ni; YUAN Jin-hong

    2005-01-01

    Objective: To observe the therapeutic effect of acupuncture therapy in the treatment of simple obesity complicated with premenstrual tension syndrome. Methods: A total of 39 cases of simple obesity complicated with premenstrual tension were treated by combination of body acupuncture and otoacupuncture based on syndrome-differentiation of traditional Chinese medicine (TCM). Symptoms, physical signs, obesity indexes and cumulative scores of clinical disease-syndrome before and after treatment were analyzed and compared. Results: After one, two and three courses of treatment, the effective rates were 69.23%, 79.49% and 87.18% respectively. Conclusion: Acupuncture therapy works well in the treatment of simple obesity with concurrent premenstrual tension syndrome.

  9. Serotonin system in premenstrual syndrome occurrence

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    Rogozhina I.E.

    2016-06-01

    Full Text Available The review presents the published data on relevance of problem, frequency rate and the mechanisms of occurrence of premenstrual syndrome, the necessity of complex treatment of premenstrual syndrome has been proved.

  10. Assessment of the effects of massage therapy on premenstrual syndrome

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    Leily Ghaedi

    2011-05-01

    Full Text Available Background: Premenstrual syndrome is characterized by the cyclic occurrence physical, psychological and behavioral symptoms during the luteal phase of the menstruation cycle and will be disappear within a few days of the onset of menstruation. The aim of this research was to assess the effect of massage therapy on premenstrual syndrome. Materials and Method: A randomized clinical trial was carried out on 30 volunteer students of Tehran University with PMS diagnosis. After surveying two menstruation cycles and confirming PMS existence, subjects were randomly assigned into massage and control group. Massage protocol was performed for eight weeks. Volunteers completed Daily Symptom Rating (DSR during 2 cycles before and 2 cycles after intervention. Data collected via data gathering form, criteria for PMS (DSM- IV, DSR and Beck test. Data were analyzed by descriptive and analytic statistics (χ2, Fischer's exact test, paired and independent t tests.Results: In comparison between before and after intervention, massage group showed significant decrease averagely in mean of somatic (56.7%, psychological (64.8% (p<0.001.This is while, in control group only mean of somatic symptoms (averagely 21.2% relieved obviously (p=0.02. comparing two groups often intervention, we did not found any significant difference in mean of somatic symptoms while psychological (p=0.01 and total symptoms (p=0.03 in massage group was significantly less than controls.Conclusion: The authors concluded that massage therapy is an effective method for relieving symptoms of premenstrual syndrome

  11. Study the Prevalence of Premenstrual Dysphoric Disorder in Hamadan High School Girls in 2003

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    A. Farhadi Nasab

    2006-04-01

    Full Text Available Introduction & Objective: Premenstrual dysphoric disorder is considered as a mood disorders that 30 to 80 percent of women have at least mild symptoms and that 2 to 10 percent have severe symptoms of this disorder. The exact cause of this disorder is not clear, but according to one of the most common theories, it seems to be the higher level of estrogen to progesterone in affected women. The symptoms of this disorder include: hopelessness, agitation, emotional disturbance, anger and physical complaints (headache, breast tenderness and edema. The symptoms cause clinically significant impairment in social, occupational or interpersonal functioning. The purpose of this study was evaluation of the prevalence of premenstrual dysphoric disorder in Hamadan high school girls, in 2003.Materials & Methods: This was a descriptive-analytic cross-sectional study. Maximum sampling error was considered to be as 5% and confidence interval was 95%. 384 educating high school girls from Hamadan were selected randomly and were asked by questionnaires that were designed on the basis of premenstrual dysphoric disorder criteria, according to psychiatric references. Data were statistically analyzed by SPSS 10 using 2 test.Results: From 384 studied girls, 172 subjects (44.5% were diagnosed with premenstrual dysphoric disorder which 18 cases of them were suspicious to have other disorder such as depression. 102 patients among affected girls (59.3% were diagnosed during the first year of beginning menstruation. Duration of symptoms of premenstrual dysphoric disorder was more than three days in 20% of cases. Mood, behavioral and physical symptoms were coexisted in 71.5%, 61% and 73.2% of the girls with premenstrual dysphoric disorder respectively, and these associations were statistically significant (p<0.01.Conclusion: Prevalence of premenstrual dysphoric disorder in Hamadan high school girls was near to its prevalence in general population (40%. More than two thirds

  12. Premenstrual Syndrome and Psychiatric Co-morbidities.

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    Ziba Taghizadeh

    2009-04-01

    Full Text Available "n    "nObjective: Premenstrual syndrome (PMS is a common disorder with prevalence rate of approximately 30%; its concurrence with psychiatric symptoms will make it a disabling condition that resists usual treatment. Objective: This study was enrolled to assess the co-morbidity of PMS and psychiatric disorders in a sample of girls with PMS compared to those without PMS. "n    "nMaterial and method : This study was conducted through a cross sectional method with 362 participants (166 with PMS and 196 healthy girls who were selected randomly and completed the demographic questionnaire, premenstrual syndrome symptom daily record scale and the symptom checklist 90-revised (SCL-90-R. "n    "nResult: According to the result of the independent t test, the mean score of all the psychiatric symptoms in the PMS group was significantly higher than those in healthy group (P<0.001. According to SCL-90-R measurement, most of the participants in the PMS group were categorized as extremely sick for somatization (44% ,obsessive-compulsive (59%, depression (58.4%, anxiety (64.5%, hostility (47% and psychoticism (69.3%; most of the participants were diagnosed as having borderline severity of disorders for interpersonal sensitivity (44.6% and paranoid (42.8% and most of the respondents with PMS (46.4% were diagnosed as healthy only for phobic anxiety. "n    "nConclusion: There is a considerable relationship between PMS and different psychiatric symptoms that can complicate the diagnosis of PMS and its treatment for the health care providers. Therefore, all health care providers who are in contact with women in their reproductive age should be sensitive to mental health status in women with PMS.

  13. Premenstrual Syndrome and Self-Medication With Opioids

    NARCIS (Netherlands)

    Qurishi, R.; Sonneborn, C.; Jong, M. de; Jong, C.A.J. de

    2013-01-01

    We have described a patient in opioid substitution treatment using heroin to treat her premenstrual complaints. After a short review of the diagnosis and etiology of premenstrual syndrome or premenstrual dysphoric disorder, the relation between premenstrual syndrome/premenstrual dysphoric disorder

  14. Prevalence and severity of the premenstrual syndrome. Effects of foods and beverages that are sweet or high in sugar content.

    Science.gov (United States)

    Rossignol, A M; Bonnlander, H

    1991-02-01

    The objective of this study was to evaluate whether certain foods and beverages that are high in sugar content or taste sweet are related to the prevalence and severity of the premenstrual syndrome. Specifically, we sought to evaluate whether consumption of "junk foods", chocolate, caffeine-free cola, fruit juices or alcoholic beverages might exert an effect on the premenstrual syndrome apart from any effects of daily consumption of beverages that are high in caffeine (caffeine-containing coffee, tea and colas). The study was based on 853 responses to a questionnaire probing menstrual and premenstrual health and certain daily dietary practices; it was mailed to female university students in Oregon. An analysis of the data revealed that the consumption of chocolate, but not of other junk foods, was related to the prevalence of the premenstrual syndrome among women with more severe premenstrual symptoms. Likewise, the consumption of alcoholic beverages (all alcoholic beverages and beer only) was related to the prevalence of the premenstrual syndrome among women with more severe symptoms, as were both fruit juice and caffeine-free soda. None of the associations was substantially altered when the daily consumption of beverages high in caffeine content was controlled for. Taken together, these data suggest that the consumption of foods and beverages that are high in sugar content or taste sweet is associated with prevalence of the premenstrual syndrome.

  15. The effect of continuous aerobic exercise on premenstrual syndrome: a randomized clinical trial

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    Mosallanejad Z

    2007-11-01

    Full Text Available Background: Premenstrual syndrome is one of the most incidencial problems in women's during reproductive age. That effect personal performance in family and society status. Varied therapeutic treatment has been studied for its promotion. The main attention was to find a method without complications. This study performed with aim of assessing effect of one period of continuous aerobic exercise on premenstrual syndrome in 18-25 years female students in jahrom medical school."nMethods: This study was a kind of semi experimental study with two group plane. Forty students were assessed for premenstrual syndrome with regular mense, without previous history of Diabetes mellitus and Thyroid, Gynecologic and psychological disease. Twenty subjects (with similar VO2 MAX were selected and randomly divided to two experimental and control groups. Data gathering was from ILPDD questionnaire concluded 11 question about signs and symptoms of mental and physical complain related to premenstrual syndrome that filled by samples. All samples have positive five complain that four of them depend on mental symptoms of premenstrual syndrome. Intensity of quantity of premenstrual syndrome and levels of estrogen and progesterone were measured. Then, exercise regime including continuous aerobic exercise, were performed for eight weeks, with frequency of three sessions every week. At the end of 8th week, posttests were repeated in the situation similar to pretest. Analytic statistic as a Nonparametric Mann-whitney test, and nonparametric Wilcoxon signed ranks test was used for comparing variables."nResults: This study showed that after two method of aerobic exercise, somatic and effective complain was decrease in case group (p>0.05. Hormonal change in two groups was not significant."nConclusion: Releaving aerobic experiences is effective for somatic and affective complains secondary to premenstrual syndrome and this plan can be replace by other methods of medical

  16. Premenstrual Syndrome (PMS) FAQ

    Science.gov (United States)

    ... PMS symptoms. Relaxation therapy may include breathing exercises, meditation, and yoga. Massage therapy is another form of relaxation therapy that you may want to try. Some women find therapies like biofeedback and self-hypnosis to be helpful. Getting enough ...

  17. Menstrual Cycle and the Prevalence of Premenstrual Syndrome/Premenstrual Dysphoric Disorder in Adolescent Athletes.

    Science.gov (United States)

    Czajkowska, Mariola; Drosdzol-Cop, Agnieszka; Gałązka, Iwona; Naworska, Beata; Skrzypulec-Plinta, Violetta

    2015-12-01

    The purpose of this study was to assess the menstrual cycle, menstrual disorders and premenstrual syndrome/premenstrual dysphoric disorder (PMS/PMDD) in girls and young women participating in competitive sports. The impact of PMS/PMDD symptoms on the quality of life was also analyzed. The prospective study encompassed 125 girls and young women with the aim to determine the presence of menstrual disorders and the prevalence of PMS/PMDD. The studied group was composed of 75 female athletes aged 16 to 22 years. The control group included 50 healthy girls and young women who did not practice competitive sports. The studied athletes and the controls prospectively evaluated their 2 consecutive menstrual cycles by using a questionnaire. The research tools were a purpose-built questionnaire, a daily log of PMS symptoms according to the American College of Obstetricians and Gynecologists' guidelines, and a daily log of PMDD symptoms based on the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, diagnostic criteria. To determine the impact of competitive sports on the menstrual cycle, menstrual disorders, and the prevalence of PMS/PMDD in girls and young women. Intensive physical exercise delayed menarche. PMDD was diagnosed in 8% and PMS in 42.4% of all respondents. The prevalence of PMDD did not differ significantly between the groups (9.33% versus 6.00%). PMS was significantly more frequent among athletes than among controls (49.33% versus 32%, P = .045). The prevalence of PMS correlated significantly with mean age (P = .00001) and age at menarche (P = .03) in athletes. PMS was more frequent in older athletes and in girls with older age at menarche. Competitive sports, older mean age, older age at menarche, length of sporting career, and intensity of training are conducive to PMS. The prevalence of PMS increases with the duration and intensification of competitive exercises. Copyright © 2015 North American Society

  18. The prevalence and risk factors of school absenteeism due to premenstrual disorders in Japanese high school students-a school-based cross-sectional study.

    Science.gov (United States)

    Tadakawa, Mari; Takeda, Takashi; Monma, Yasutake; Koga, Shoko; Yaegashi, Nobuo

    2016-01-01

    Premenstrual disorders such as premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) interfere with the daily lives of adolescents. The causes of PMS and PMDD are unknown, but lifestyle habits, such as regular exercise and taste preference are known to be associated. This study was conducted to investigate how premenstrual symptoms affect the school life in Japanese high school students and whether there was a risk factor for school absenteeism that is dependent on the types of premenstrual symptoms or lifestyle habits. A school-based survey was conducted in Sendai, an industrial city in Japan. A total of 901 girls aged 15-19 with regular menstrual cycles were assessed using the self-reporting premenstrual symptoms questionnaire (PSQ) and questions regarding school absence, taste preference, and exercise. We classified the girls into 'no/mild PMS', 'moderate-to-severe PMS' and 'PMDD' according to the PSQ. The girls were classified into the 'absent' group if they were absent for more than 1 day per month. We used multivariate logistic analysis to examine the risk factors for school absenteeism. The rates of 'moderate-to-severe PMS' and 'PMDD' were 9.9 and 3.1 %, respectively. A total of 107 girls (11.9 %) were classified into the 'absent' group. Significant differences were observed in the prevalence of all premenstrual symptoms (p absenteeism. One in nine Japanese female high school students were absent from school due to premenstrual symptoms. Physical premenstrual symptoms and lifestyles, such as a preference for salty food and a lack of regular exercise, were identified as risk factors for school absenteeism.

  19. Systematic Review of Premenstrual, Postmenstrual and Infertility Disorders of Vitex Agnus Castus

    Science.gov (United States)

    Rafieian-Kopaei, Mahmoud; Movahedi, Mino

    2017-01-01

    Introduction Vitex agnus-castus, also called vitex is aboriginal to the Mediterranean region, with long leaves, tender stem, flowers and ripening seeds. The aim of this study was to overview premenstrual, postmenstrual and infertility disorder of Vitex agnus-castus. Methods This review article was carried out by searching studies in PubMed, Medline, Web of Science, and IranMedex databases. The initial search strategy identified about 87 references. In this study, 43 studies were accepted for further screening, and met all our inclusion criteria (in English, full text, therapeutic effects of Vitex agnus-castus and dated mainly from the year 2009 to 2016). The search terms were Vitex agnus-castus, premenstrual, postmenstrual, infertility disorder properties and pharmacological effects. Result Vitex agnus-castus was shown to contribute to the treatment of premenstrual syndrome (PMS). Moreover, the result of the present study showed that this valuable plant is helpful in alleviation of pain resulting from postmenstrual disease. Furthermore, it was found that Vitex agnus-castus is beneficial in infertility disorder. Conclusion Vitex agnus-castus (AC) is a phytopharmaceutical compound and is shown to be widely used to treat PMS and PMDD. In addition, it was shown to be beneficial in post-menstrual cases and it can also contribute to treatment of infertility cases in both men and women. Dopaminergic compounds available in this plant help to treat premenstrual mastodynia as well as other symptoms of the premenstrual syndrome. PMID:28243425

  20. PREMENSTRUAL SYNDROME IN YOUNG GIRLS - ACADEMIC LOSS/WORK PRODUCTIVITY

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    Vijayalakshmi

    2015-10-01

    Full Text Available INTRODUCTION: Premenstrual syndrome is a common problem in young girls which adversely affects their educational performance and emotional well - being. PMS is associated with reductions in health - related quality of life and work productivity impairment regardless of the criteria used. We evaluated the loss the work productivity and functional impairment adolescent girls associated with premenstrual symptoms and dysphoric disorder (PMDD. METHODS: A total of 100 unmarried girls who had regular cycles for last 6 months, between the age group of 13 - 19 years, having dysmenorrhic symptoms and having a menstrual cycle length 0f 21 - 35 days were enrolled. Data was collected on Socio economic profile menstrual profile, PMS symptoms ACOG, DSM - IV (PMDD & Work productivity loss & Impairment. Symptoms were recorded. RESULTS: Physical symptoms, the highest % of symptoms are with Abdominal Bloating (95.81%; Breast Discomfort (94.72%; Acne (93.44%; Body ache (90.71%; Increased appetite (87.43%. Psychological symptoms - Angry (94.35% >Anxiety (92.71% >Irritability (91.44% >Feeling depressed (90.35% >Feeling Stress (85.97%. Behavioral S ymptoms: - Personality Change (85.6% >Abstinence from Work (80.5% >Violent Outburst (77.9% Work Productivity Loss and Functional I mpairment: - 27.1% have reported to have a loss of more than 2 days; 12% have reported to have loss of more than 5 days; 2% have reported to have a loss of more than 14 days. CONCLUSION: In the present study, 41% had academic/ work loss. 24% of PMS patients who missed more than 5 days per month with 50% reduction in work productivity and 2% missed more than 14 days per month with impairment in work/social activities/relationships.

  1. [Evaluating the relation of premenstrual syndrome and primary dysmenorrhea in women diagnosed with fibromyalgia].

    Science.gov (United States)

    Terzi, Rabia; Terzi, Hasan; Kale, Ahmet

    2015-01-01

    In this study, we aimed to investigate the presence of premenstrual syndrome (PMS), primary dysmenorrhea (PD) and depression among women with fibromyalgia (FM) and healthy females and to determine possible factors related with PMS and PD in FM. The present study was conducted on 98 female patients diagnosed with FM and 102 age and sex-matched healthy controls. All patients were evaluated for premenstrual syndrome (PMS) and primary dysmenorrhea (PD). Premenstrual syndrome was assessed among the patients for the presence of one or more affective or somatic symptoms within the five days preceding menses. The diagnosis of primary dysmenorrhea was defined as having abdominal pain or lower back pain lasting at least two days during a menstrual period. Dysmenorrhea was assessed via visual analog scale. Dysmenorrhea was rated via Multidimensional Scoring System. The Hamilton depression scale was applied to all patients. Primary dysmenorrhea was established in 41% of FM patients and 28% of the control group. A statistically significant difference was found in PD between the two groups (p=0.03). PMS was established in 42% of the FM patients and 25% of the control group. A statistically significant difference was found in PMS between the two groups (p=0.03). There is an increased frequency of premenstrual syndrome and dysmenorrhea in FM patients. The patients with high symptom severity scores and high depression scores among the FM patients are at risk of PMS and PD. Copyright © 2015 Elsevier Editora Ltda. All rights reserved.

  2. Treatment of Moderate to Severe of Premenstrual Syndrome with

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    Masoumeh Delaram

    2014-03-01

    Full Text Available Background: Premenstrual Syndrome (PMS is the appearance of annoying symptoms, disrupting women's daily activities as well as inducing problems. Different treatment were suggested for its and the method with the least side effects will be preferred. The aim of this study was to determine the effect of Echinophora platyloba extract on PMS in the students of Shahr-e-Kord University Of Medical sciences in Iran. Materials and Methods: Sixty students having moderate to severe PMS, participated in a single-blind randomized clinical trial. The students were randomly assigned into two equal groups. The first group received the Echinophora platyloba (E. platyloba extract and the second group received placebo. The Daily Record of Severity of Problem (DRSP questionnaire was used to quantify PMS severity before and after the intervention. At the end of first and second cycles after the intervention, the severity of PMS was detected and compared with before intervention. Data analysis was performed by using Mann-Whitney U, Wilcoxon and Pearson correlation test. Results: There was not a significant difference in the severity of premenstrual syndrome between the E. platyloba and placebo group before the intervention (100.8±22.1 vs. 104.3±19.5. A significant difference was found between two groups after the intervention [(49.7±23.2 vs. 79.1±28.1, p=0.002]. Conclusion: E. platyloba extract is probably effective in the treatment of premenstrual syndrome. Using of this herbal extract is suggested for the treatment of PMS.

  3. Pyridoxine (vitamin B6) and the premenstrual syndrome: a randomized crossover trial.

    Science.gov (United States)

    Doll, H; Brown, S; Thurston, A; Vessey, M

    1989-09-01

    A randomized double-blind crossover trial was conducted to study the effects of pyridoxine (vitamin B6) at a dose of 50 mg per day on symptoms characteristic of the premenstrual syndrome. Sixty three women aged 18-49 years, identified by means of a general practice based survey of menstrual patterns in the community, entered the trial. All of the women had noticed moderate to severe premenstrual symptoms during the previous year. The women kept a daily menstrual diary which graded the severity of nine individual symptoms from zero to three. After completing a diary for an initial month the women were randomized to receive either drug or placebo for three months, after which the treatments were crossed over for a further three months. Thirty two women completed the full seven months of the study. In these women a significant beneficial effect (P less than 0.05) of pyridoxine was observed on emotional type symptoms (depression, irritability and tiredness). No significant effect was observed on premenstrual symptoms of any other type.

  4. Effect of Premenstrual Syndrome on Work-Related Quality of Life in Turkish Nurses.

    Science.gov (United States)

    Kahyaoglu Sut, Hatice; Mestogullari, Elcin

    2016-03-01

    Little is known about the effects of premenstrual syndrome (PMS) on work-related quality of life in nurses. We aimed to investigate the effect of PMS on work-related quality of life in Turkish nurses. A total of 134 volunteer nurses were included in this cross-sectional study between January 2015 and March 2015. One hundred and thirty-four nurses completed a questionnaire regarding demographic data, the Premenstrual Syndrome Scale (PMSS), and the Work-Related Quality of Life Scale (WRQoL). The nurses were classified as having or not having premenstrual syndrome according to the PMSS. The average age was 29.5 ± 7.1 years and the prevalence of PMS was 38.1%. The total score of PMSS was significantly negatively correlated with the overall score (r = -0.341; p work (p = 0.179) in nurses with PMS were significantly lower than those of nurses without PMS (p work-related quality of life in their professional lives. Methods to help cope with cyclic premenstrual symptoms may be used, and as a result, productivity and work-related quality of life may increase.

  5. Toxoplasma gondii Infection and Premenstrual Dysphoric Disorder: A Cross-Sectional Study

    Science.gov (United States)

    Alvarado-Esquivel, Cosme; Sanchez-Anguiano, Luis Francisco; Hernandez-Tinoco, Jesus; Perez-Alamos, Alma Rosa; Rico-Almochantaf, Yazmin del Rosario; Estrada-Martinez, Sergio; Vaquera-Enriquez, Raquel; Diaz-Herrera, Arturo; Ramos-Nevarez, Agar; Sandoval-Carrillo, Ada Agustina; Salas-Pacheco, Jose Manuel; Cerrillo-Soto, Sandra Margarita; Antuna-Salcido, Elizabeth Irasema; Liesenfeld, Oliver; Guido-Arreola, Carlos Alberto

    2016-01-01

    Background Premenstrual dysphoric disorder is a severe form of premenstrual syndrome. The influence of Toxoplasma gondii (T. gondii) infection on clinical features in women with this disorder has not been studied. Therefore, we determined the association of T. gondii infection with symptoms and signs in women suffering from premenstrual dysphoric disorder. Methods We performed a cross-sectional study of 151 women suffering from premenstrual dysphoric disorder. Anti-Toxoplasma IgG and IgM antibodies were detected in sera of the participants using enzyme-linked immunoassays (EIAs). In addition, T. gondii DNA was detected in whole blood of IgG seropositive participants using polymerase chain reaction. We obtained the clinical data of women with the aid of a questionnaire. The association of T. gondii infection with clinical characteristics of women was assessed by bivariate and multivariate analyses. Results Anti-T. gondii IgG antibodies were found in 10 (6.6%) of the 151 women studied. Of the 10 IgG seropositive women, four (40.0%) were positive for anti-T. gondii IgM antibodies, and one (10.0%) for T. gondii DNA. Mean number (25.8 ± 7.58) of premenstrual clinical characteristics in seropositive women was similar to that (29.22 ± 9.13) found in seronegative women (P = 0.25). Logistic regression showed that seropositivity to T. gondii was negatively associated with difficulty concentrating (OR: 0.18; 95% CI: 0.03 - 0.91; P = 0.03), and positively associated with out of control feeling or overwhelmed (OR: 9.00; 95% CI: 1.32 - 62.00; P = 0.02). Conclusions Results of this first study on the association of T. gondii infection and clinical characteristics of premenstrual dysphoric disorder suggest that this infection might be linked to some symptoms of this disorder. We report for the first time the association of T. gondii infection and out of control feeling or overwhelmed. Results warrant for further research on the role of T. gondii in premenstrual dysphoric

  6. [The possibility for treating the premenstrual syndrome with Periodin].

    Science.gov (United States)

    Rachev, E; Nalbanski, B; Stamenov, G

    2000-01-01

    We examined the possibility of treatment of premenstrual syndrome (PMS) with Periodin (Walmark). Periodin is a combination of polyvitamins, oligoelements and phytoextracts which have a relation with prostaglandin's synthesis and regulation of prolactin secretion. A group of 24 women with PMS and regular cycles in premenopausal period (mean age of 44.7) was examined and took Periodin 1-2 caps daily for a period of 3 months as a food supplement. The assessment was made by modified J. Mortola score system. After treatment the PMS symptoms decreased with 52.3% compared with the beginning. The authors conclude that Periodin has a considerable influence on PMS symptoms, no contraindications and could be useful widely in gynecological practice.

  7. Effect of acupressure vs reflexology on pre-menstrual syndrome among adolescent girls--a pilot study.

    Science.gov (United States)

    Padmavathi, P

    2014-01-01

    Premenstrual syndrome is the most common of gynaecologic complaints. It affects half of all female adolescents today and represents the leading cause of college/school absenteeism among that population. It was sought to assess the effectiveness of acupressure Vs reflexology on premenstrual syndrome among adolescents. Two-group pre-test and post-test true experimental design was adopted for the study. Forty adolescent girls from Government Girls Secondary School, Erode with pre- menstrual syndrome fulfilling the inclusion criteria were selected by simple random sampling. A pre-test was conducted by using premenstrual symptoms assessment scale. Immediately after pre-test acupressure Vs reflexology was given once a week for 6 weeks and again post-test was conducted to assess the effectiveness of treatment. Collected data was analysed by using descriptive and inferential statistics. In post-test, the mean score of the experimental group I sample was 97.3 (SD = 2.5) and the group II mean score was 70:8 (SD = 10.71) with paired 't' value of 19.2 and 31.9. This showed that the reflexology was more effective than acupressure in enhancing the practice of the sample regarding pre-menstrual syndrome. Statistically no significant association was found between the post-test scores of the sample with their demographic variables. The findings imply the need for educating adolescent girls on effective management of pre-menstrual syndrome.

  8. Perception of premenstrual syndrome and attitude of evaluations of work performance among incoming university female students.

    Science.gov (United States)

    Cheng, Shu Hui; Sun, Zih-Jie; Lee, I Hui; Shih, Chi-Chen; Chen, Kao Chin; Lin, Shih-Hsien; Lu, Feng-Hwa; Yang, Yi-Ching; Yang, Yen Kuang

    2015-01-01

    Premenstrual syndrome (PMS) is a common condition, and for 5% of women, the influence is so severe as to interfere with their mental health, interpersonal relationships, or studies. Severe PMS may result in decreased occupational productivity. The aim of this study was to investigate the influence of perception of PMS on evaluation of work performance. A total of 1971 incoming female university students were recruited in September 2009. A simulated clinical scenario was used, with a test battery including measurement of psychological symptoms and the Chinese Premenstrual Symptom Questionnaire. When evaluating employee performance in the simulated scenario, 1565 (79.4%) students neglected the impact of PMS, while 136 (6.9%) students considered it. Multivariate logistic regression showed that perception of daily function impairment due to PMS and frequency of measuring body weight were significantly associated with consideration of the influence of PMS on evaluation of work performance. It is important to increase the awareness of functional impairments related to severe PMS.

  9. The Effect of Premenstrual Syndrome on Quality of Life in Adolescent Girls

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    Mohammad Arbabi

    2008-08-01

    Full Text Available "n Objective: "n "nPremenstrual Syndrome (PMS is a common psychosomatic disorder and about 30%-50% of women in the childbearing age suffer from mild to moderate form of this disorder and 3%-8% suffer from its sever form. The symptoms of this disorder are related to the specific biological characteristics of women's reproductive age that can start from teen years. The symptoms' devastating effect on these crucial years of life can result in a sense of dissatisfaction and inadequacy. The purpose of this study was to determine the correlation between premenstrual syndrome (PMS and quality of life (QOL in adolescent girls. "nMethod: This research is a descriptive-analytic study. The participants were 360 adolescent girls (180 in each group, studying in the second year of high school in south of Tehran. The participants were selected in a multistage randomly- clustered design according to their schools. Respondents completed the demographic questionnaire, premenstrual syndrome symptom daily record scale, and the medical study short form-36 (SF-36. "nResults: Compared with healthy adolescents, those with PMS had a lower score of SF-36 in all the scales (P<0.001. Except for mental health and vitality, no significant difference was observed between other scales of quality of life according to SF-36 in various severities of PMS (P>0.05. However, a statistically meaningful difference was observed in mental health and vitality of SF-36 in severe form of PMS in compare to mild and moderate PMS P=0.002. "nConclusion: Premenstrual syndrome is associated with substantial burden on QOL in adolescents. In addition, increasing severity in PMS symptoms results in decreased quality of mental health and vitality.

  10. Premenstrual dysphoric disorder in medical students residing in hostel and its association with lifestyle factors

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    Amrita Mishra

    2015-01-01

    Full Text Available Context: There is scant research on premenstrual syndrome (PMS and its more severe counterpart, premenstrual dysphoric disorder (PMDD in Indian females. This study aimed to evaluate symptoms of PMS in medical students and to find the association of sociodemographic variables and lifestyle factors with PMDD. Subjects and Methods: A total of 179 medical students residing in the hostel of an Indian medical college and its affiliated teaching hospital were approached, of which 100 (55.8% returned the completed questionnaires. Data related to lifestyle factors was collected. Self-screening quiz for Diagnostic and Statistical Manual of Mental Disorders-IV-Text Revision PMDD and Shortened Premenstrual Assessment Form were used for diagnosis of PMDD and detection of symptomatology, respectively. Results: PMDD was present in 37% of the respondents. It was found at a higher rate in older and postgraduate students. PMDD was significantly associated with lifestyle factors, namely, sleep, physical activity, total tea/coffee intake, and change in tea/coffee and food intake under stress. The most common physical and psychological symptoms were body ache/joint pain and feeling depressed/blue, respectively. Conclusions: PMDD is fairly common in Indian medical students residing in hostel although cultural factors may influence symptom expression. This study suggests that PMDD is associated with lifestyle factors in young, professional, urban women. Modification in lifestyle may thus be an important approach for management of PMS/PMDD. Prospective studies with larger representative samples are needed to validate these findings.

  11. Prevalence of premenstrual syndrome among women of child-bearing age with regular menstrual cycle

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    Nodira Khodjaeva

    2013-11-01

    Full Text Available The study on prevalence of premenstrual syndrome (PMS with various severities was conducted in a cohort of fertile female residents of Tashkent aged from 18 to 30. Clinical and medical history data on psycho-emotional and physical PMS symptoms was put into a specially developed card-questionnaire. Severity of symptoms was determined by total score to fill in a PMS symptom scale on the basis of the examinees’ self-observation. The associations of PMS with social-demographic factors, such as, level of education, employment status, sexual satisfaction and stress index were analyzed.

  12. Efficacy of Vitamin B6 in the Treatment of Premenstrual Dysphoric Disorder

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    M Maaroofi

    2004-06-01

    Full Text Available Background: Many etiological factors have been proposed for Premenstrual Dysphoric Disorder (PDD and different drugs and techniques have been suggested for its treatment. This study was designed to assess the efficacy of vitamin B6 in the treatment of PDD. Methods: In a randomized double-blind placebo controlled study, 121 Women, aged 20-45 years, who according to DSM-4 criteria, had PDD were randomly divided into two groups to receive orally either vitamin B6 (group A 40 mg twice daily during luteal phase of their menstrual cycle or starch as placebo. Vitamin B6 and starch both were prepared in gelatin capsules with the same shape and color. Emotional and somatic scores for the severity of PDD symptoms were determined and compared between the two groups. Results: Emotional score decreased significantly in group A compared to group B and basal value. No changes in somatic scores were observed. Conclusion: It seems that vitamin B6 is an effective drug for relief of emotional symptoms in PDD. Keywords: Premenstrual Dysphric Disorder, Vitamin B6, Premenstrual Tension.

  13. Premenstrual Syndrome in Turkish college students and its effects on life quality.

    Science.gov (United States)

    Pinar, Gul; Colak, Meric; Oksuz, Ergun

    2011-01-01

    The purpose of this research is to analyze the frequency of Premenstrual Syndrome (PMS) in college students, the factors affecting Premenstrual Syndrome and the effect of Premenstrual Syndrome on life quality. The research was performed on 316 students who study at Medical Sciences Faculty of Başkent University and accepted to take part in the research. The data of the research was compiled by using "Questionnaire Form", "PMS Rating Scale" and "Life Quality Scale" developed by the researchers. In the analysis of the data; Percentage distribution, Chi-square test, One Way Anova test, Logistic regression, Multi nominal regression analysis were used. PMS was detected in 72.1% of the students. The most frequent symptoms are mainly low back pain, stress-discomfort, nervous-anger, distention and breast tenderness. PMS was found significantly high in those students who have menstrual irregularity, who have dysmenorrhea, who consume 2 cups of coffee or above per day and who smoke and drink alcohol (pstudents and this adversely affects the life quality. It was revealed that the preventive, instructive and consultancy roles of the medical staff became more of an issue in reducing the effect of the factors causing and/or aggravating these symptoms in order to decrease PMS incidence and to improve the life quality of the students. Copyright © 2010. Published by Elsevier B.V.

  14. Development of a screening instrument to assess premenstrual dysphoric disorder as conceptualized in DSM-5.

    Science.gov (United States)

    Aperribai, Leire; Alonso-Arbiol, Itziar; Balluerka, Nekane; Claes, Laurence

    2016-09-01

    This study aimed at developing and validating a screening instrument to assess premenstrual dysphoric disorder (PMDD) based on DSM-5 criteria, which is not yet available. The Premenstrual Dysphoric Disorder Questionnaire for DSM-5 (Cuestionario del Trastorno Disfórico Premenstrual - DSM-5), a 25-item questionnaire to assess PMDD was developed and completed in Spanish by 2820 women (Age M=23.43; SD=7.87). Exploratory factor analysis (N=1410) and confirmatory factor analysis (N=1410) were performed in randomly selected subsamples. Empirical evidence of construct validity was obtained via a multitrait-multimethod approach (N=118). Additional validity evidence was provided by associating PMDD with Neuroticism. Internal consistency and test-retest reliability were checked. Exploratory and confirmatory factor analyses yielded a bi-dimensional structure. The first dimension, called Dysphoria, included dysphoric symptoms and weight gain; the second dimension, Apathy, referred to apathetic and physical symptoms. Both dimensions displayed good internal consistency coefficients (Dysphoria's ordinal alpha=0.88; Apathy's ordinal alpha=0.84), and moderate temporal stability. The multitrait-multimethod analysis showed that convergent coefficients were higher than discriminant coefficients. Furthermore, a positive relationship between Neuroticism and PMDD was observed. These findings suggest that the instrument is valid and reliable to assess PMDD. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. The effect of Valerian root extract on the severity of pre menstrual syndrome symptoms

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    Zahra Behboodi Moghadam

    2016-07-01

    A significant difference was seen in mean emotional, behavioral and physical premenstrual symptom severity in the intervention group before and after the intervention (P < 0.001. However, this difference was not statistically significant in the control group. The results of this study showed that Valerian root extract may reduce emotional, physical, and behavioral symptoms of premenstrual syndrome.

  16. Role of danazol in relieving the premenstrual syndrome.

    Science.gov (United States)

    Derzko, C M

    1990-01-01

    Approximately 90% of women experience some symptoms of the premenstrual syndrome (PMS); in up to 40% of cases the symptoms are moderate to severe. The signs and symptoms of PMS usually wax and wane according to a four-phase temporal pattern. Within this overall schema there are a number of PMS subtypes. PMS typically manifests before the age of 30 and rarely resolves spontaneously. While genetic factors may play a role in the development of PMS, other epidemiologic factors do not seem to be involved. Various pathophysiologic mechanisms have been proposed as causing PMS. They are an estrogen/progesterone imbalance, prolactin abnormalities, fluid retention, abnormal production of certain prostaglandins, hypoglycemia, pyridoxine deficiency and shifting levels of endorphins. However, the role of these factors in the etiology of PMS has not been established definitively; thus, treatment remains largely empiric. The author's experience with the use of Danocrine (danazol) on 21 patients with PMS suggests that this synthetic steroid, when used in conjunction with nonpharmacologic treatment options, relieves the symptoms of PMS in up to 85% of patients. Women whose PMS is characterized primarily by mastalgia appear to respond most favorably to treatment; danazol is not recommended for women with primary depression or anxiety symptomatology.

  17. [Serotonin uptake inhibitors provide rapid relief from premenstrual dysphoria. New findings shed light on how serotonin modulates sex hormone-related behavior].

    Science.gov (United States)

    Eriksson, E; Andersch, B; Ho, H P; Landén, M; Sundblad, C

    2001-08-22

    Premenstrual dysphoria (PMD) is a severe form of premenstrual syndrome, afflicting 5-10% of all women. The cardinal symptom--surfacing between ovulation and menstruation, and disappearing within a few days after the onset of the bleeding--is irritability. Serotonin reuptake inhibitors (SRIs), but not non-serotonergic antidepressants, reduce the symptoms of PMD very effectively. Since the, onset of action of SRIs is rapid when used for PMD, medication may be restricted to the luteal phase. The finding that SRIs are effective for PMD lends support for the hypothesis that a major role for brain serotonin is to modulate sex steroid-driven behavior.

  18. Evidence for altered transcapillary fluid balance in women with the premenstrual syndrome.

    Science.gov (United States)

    Tollan, A; Oian, P; Fadnes, H O; Maltau, J M

    1993-05-01

    Redistribution of body fluids has been suggested as a possible pathophysiological mechanism for the premenstrual syndrome (PMS). To elucidate this hypothesis, transcapillary fluid balance was studied in ten women with well defined PMS. Wick-methods were used for measuring colloid osmotic and hydrostatic interstitial pressures on the thorax and on the leg. The capillary filtration coefficient was measured by strain gauge plethysmography. From the follicular to the luteal phase the interstitial colloid osmotic pressure on the leg was significantly reduced (mean 3.6 mm Hg, p = 0.005), whereas the interstitial colloid osmotic pressure on the thorax remained constant. The capillary filtration coefficient increased 30% (mean 5.3 x 10(-4) ml/min/100 gm/mm Hg, p = 0.04) from the follicular to the luteal phase. No change was observed in body weight. These findings indicate an instability of vascular regulation in women with premenstrual syndrome, and lend support to the hypothesis that redistribution of fluid, rather than water retention, is responsible for the subjective symptoms such as bloatedness, in the premenstrual syndrome.

  19. An overview of four studies of a continuous oral contraceptive (levonorgestrel 90 mcg/ethinyl estradiol 20 mcg) on premenstrual dysphoric disorder and premenstrual syndrome

    DEFF Research Database (Denmark)

    Freeman, Ellen W; Halbreich, Uriel; Grubb, Gary S

    2012-01-01

    This article presents an overview of four studies that evaluated a continuous oral contraceptive (OC) containing levonorgestrel (90 mcg) and ethinyl estradiol (20 mcg; LNG/EE) for managing premenstrual dysphoric disorder (PMDD) and premenstrual syndrome (PMS).......This article presents an overview of four studies that evaluated a continuous oral contraceptive (OC) containing levonorgestrel (90 mcg) and ethinyl estradiol (20 mcg; LNG/EE) for managing premenstrual dysphoric disorder (PMDD) and premenstrual syndrome (PMS)....

  20. The efficacy of Femal in women with premenstrual syndrome: a randomised, double-blind, parallel-group, placebo-controlled, multicentre study

    DEFF Research Database (Denmark)

    Gerhardsen, G.; Hansen, A.V.; Killi, M.

    2008-01-01

    Introduction: A double-blind, placebo-controlled, randomised, parallel-group, multicentre study was conducted to evaluate the effect of a pollen-based herbal medicinal product, Femal (R) (Sea-Band Ltd, Leicestershire, UK), on premenstrual sleep disturbances (PSD) in women with premenstrual syndrome...... (PMS). Methods: Femal, 160 mg twice-daily, was given for four menstrual cycles to 50 women, and placebo to 51 women. PSD were evaluated on a visual analogue scale prior to and after the four cycles. The effect on overall PMS symptoms was assessed with the Steiner premenstrual tension syndrome (PMTS......) self-rating questionnaire. The results were analysed statistically based on intention to treat. Results: Femal treatment resulted in a significant reduction in PSD (P 0.05). In a subgroup analysis of women with irritability as their main PMS...

  1. Prevalência da Síndrome Pré-menstrual e seus Principais Sintomas Observados em Acadêmicas do Curso de Medicina de uma Faculdade do Sul de Minas Gerais Prevalence of Premenstrual Syndrome and its Main Symptoms Observed in Students of a Medical School Course in the South of

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    Prevalência da Síndrome Pré-menstrual e seus Principais Sintomas Observados em Acadêmicas do Curso de Medicina de uma Faculdade do Sul de Minas Gerais/Prevalence of Premenstrual Syndrome and its Main Symptoms Observed in Students of a Medical School Cours

    2013-06-01

    Full Text Available Objetivos: Avaliar a presença da síndrome pré-menstrual (SPM e sua intensidade, bem como os principais sintomas relacionados em acadêmicas do curso de medicina da Faculdade de Medicina de Itajubá. Materiais e Métodos: Foi realizado um inquérito com mulheres que ingressaram no curso entre os anos de 2005 a 2011, através de um questionário em que as acadêmicas eram classificadas de acordo com a intensidade dos sintomas de SPM e agrupadas em um tipo de sintoma principal. Resultados e Discussão: A ocorrência da SPM foi observada em 100% das acadêmicas entrevistadas em todos os anos, independentemente da série, ou seja, todas as acadêmicas apresentaram algum sintoma, mesmo que leve, da SPM. No entanto, o 2° ano letivo foi o que teve a maior média de sintomas (média de 41,7 pontos da SPM, e o 6°, a menor (média de 36,1. Quanto às características de sintomas das acadêmicas, as manifestações mais citadas foram a irritabilidade e compulsividade. Conclusão: A alta prevalência da SPM foi observada em todos os anos entrevistados, indo de encontro com a literatura, que indica a presença da síndrome em mulheres de todo o mundo, tornando necessária a existência de estudos que facilitem o diagnostico precoce com seu respectivo tratamento mais adequado, reduzindo seus efeitos no cotidiano das mulheres. Objectives: To evaluate the presence of Premenstrual syndrome (PMS and its intensity, as well as major academic-related symptoms in the course of medicine at Medical College of Itajubá. Materials and Methods: A survey was conducted with women who entered the course between the years 2005 to 2011, through a questionnaire the students were classified according to the intensity of the symptoms of PMS and grouped into one type of symptom page. Results and Discussion: The occurrence of PMS was observed in 100% of academic respondents in every year, regardless of the series, all academic exhibited some symptoms, even mild PMS. However

  2. ACUPUNCTURE TREATMENT OF FEMALE OBESITY COMPLICATED WITH PREMENSTRUAL TENSION SYNDROME

    Institute of Scientific and Technical Information of China (English)

    LIU Zhi-cheng; SUN Feng-min; XU Bing-guo; YUAN Jin-hong; XU Bin; L(U) Ya-ni; SU Xiao-qing

    2005-01-01

    Objective: To explore mechanisms of acupuncture for the treatment of obesity complicated with premenstrual tension syndrome (PTS). Methods: By means of syndrome-differentiation, 45 female simple obese (SO) patients with PTS (SO+PTS group and 35 simple obesity patients (SO group) were treated with body acupuncture combined with ear acupuncture. Thirty-three normal women subjects were assigned to control group. Changes in symptoms, signs, obesity index, clinical indices of disease and syndrome, equilibrium index of the vegetative nervous system (Y value), blood estradiol (E2), progesterone (P), aldosterone (Ald) and lipid levels were detected and compared before and after the treatment. Results: Before acupuncture treatment, the obesity index, clinical indices of disease and syndrome, Y value, E2/P ratio and Ald in these patients were obviously increased, and E2 and P levels decreased. After the treatment, the body weight of the patients was reduced, and the increased obesity index, clinical indices of diseases and syndromes, Y value, E2/P ratio and Ald were markedly lowered (P<0.05, or P<0.01), and the decreased E2 and P levels elevated significantly (P<0.01). Conclusion: Acupuncture exerts favorable regulative function on clinical indices of disease and syndrome, Y value, E2, P, Ald, lipid and E2/P in obese patients with PTS, which may be related to its resultant improvement of the functions of the hypothalamo-pituitary-gonadal axis, hypothalamo-pituitary-adrenal axis and the vegetative nervous system.

  3. Theory and methodology in premenstrual syndrome research.

    Science.gov (United States)

    Walker, A

    1995-09-01

    Premenstrual Syndrome (PMS) is a controversial and ill-defined phenomenon, the aetiology of which remains an enigma, despite considerable research effort. In this paper, four meta-theoretical approaches to PMS are described and evaluated. Approaches to PMS can be criticised on three inter-related grounds. They have failed to describe women's experiences in detail before explaining them; they have not placed experience within its socio-cultural context; and they have assumed a linear relationship between biology or culture and behaviour. Future research can address these issues in two ways. Biopsychosocial models of PMS may integrate a variety of approaches and improve our understanding of individual experiences but are unlikely to offer new insights into the phenomenon of PMS. These are more likely to emerge from anthropological and sociological studies which question the cultural and individual meaning of PMS.

  4. 不同个性中国女大学生经前期综合征的症状及其应对方式研究%Relationships between premenstrual syndrome symptoms and coping styles in female college students with different personalities

    Institute of Scientific and Technical Information of China (English)

    张永爱; 安瑞芳; 唐争艳; 李静; 张海苗

    2013-01-01

    目的 探讨不同个性类型女大学生经前期综合征(premenstrual syndrome,PMS)相关症状及其应对方式的差异,为不同个性女大学生经前期综合征制定个体化干预方案提供科学依据.方法 通过多阶段分层整群随机抽样的方法,抽取中国不同地区12所大学,72个班2508名女大学生为调查对象,采用艾森克人格问卷、月经症状量表以及月经应对方式量表进行调查.资料分析利用SPSS Windows Program 18.0进行单向分类-方差分析.结果 不同个性女大学生经前期综合征的症状总分之间,差异有统计学意义(F=53.38,P<0.001).不同个性女大学生的PMS症状6个领域即疼痛、注意力下降、行为改变、自主神经反应、钠水潴留、否定情绪反应分数之间,差异亦均有统计学意义(P <0.001).内向稳定型和外向稳定型、内向不稳定型和外向不稳定型分数之间差异无统计学意义(P>0.05),但内向稳定型、外向稳定型分别与内向不稳定型、外向不稳定型分数进行比较,不稳定型得分高,差异有统计学意义(P均<0.001).不同个性女大学生PMS各种应对方式即一般应对方式、积极行为应对方式、积极认知应对方式、消极应对方式的分数之间,差异均有统计学意义(P<0.001).内向稳定型分别和内向不稳定型、外向稳定型、外向不稳定型分数比较差异有统计学意义(P均<0.001).结论 不同个性女大学生的PMS相关症状及其应对方式存在差异,应根据不同个性类别给予针对性的干预方案,为女大学生个体化性健康教育程序的制定提供可靠的理论依据.%Objective To explore the relationships between premenstrual syndrome (PMS) symptoms, coping styles and personalities, and to provide scientific basis for making the individual intervention plans of PMS to female college students with different personalities. Methods Through multistage stratified cluster random sampling, the

  5. The relationship between Exercise and premenstrual syndrome

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    Ameneh Safarzadeh

    2016-09-01

    Full Text Available Premenstrual syndrome (PMS starts during puberty years and it continues to the menopausal period. PMS manifests itself during every monthly luteal stage in the form of a complex of somatic, psychological and behavioral disorders. Exercises such as walking, cycling, swimming and slow running are a few suitable methods for settling down the tension and eliminating the PMS. It is evident that sport in comparison to the therapeutically drugs is free from side effects and it is devoid of any risks. Therefore, the objective of the present study is assessing the relationship between exercises and premenstrual syndrome (PMS. The present descriptive-analytical study has been conducted on 160 students of Zahedan University of Medical Sciences in 2014-2015 academic year. For gathering data a two-section questionnaire was used. The first section was related to the demographic features and the second section pertained to PSTT standard questionnaire. The questionnaires were completed in three consecutive periods of the menstrual cycle by the students based on a self-report method. Gathered data w analyzed by through SPSS 19.0. The statistical tests were used such as the descriptive statistical tests, Chi square and independent samples t-test. The participators’ average age was 21.06 ± 2.19. The subjects did exercise s ( 86 students less than twice a week, did physical activities between 2 and 4 days in a week (44 students and 30 subjects did exercises more than 4 times weekly. They had experiences of dysmenorrhea during their menstrual cycle (120 subjects. There was not observed a significant relationship between age and PMS (P>0.05. The relationship between the individuals citizenship with PMS was statistically significant (P=0.04. The relationship between sport and PMS in three measured periods was statistically significant (P<0.05. The results obtained from the present study indicated that doing regular physical exercises and continuous sport can be

  6. Stress reactivity and emotion in premenstrual syndrome

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    Liu Q

    2017-06-01

    Full Text Available Qing Liu,1 Yongshun Wang,2 Cornelis Hermanus van Heck,3 Wei Qiao4 1Department of Nuclear Medicine and Medical PET Center, The Second Hospital of Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 2School of Physical Education and Sport, Huaqiao University, Xiamen, People’s Republic of China; 3DCC, Donders Institute for Neuroscience and Neurocognition, Arnhem, the Netherlands; 4Department of Physical Education, Xiamen Institute of Technology, Xiamen, People’s Republic of China Background: Hormone level fluctuation across the menstrual cycle causes women to experience negative emotions and also affects their mood regulation and stress sensitivity. However, the stress reactivity and emotional variations in women with premenstrual syndrome (PMS, who are especially sensitive to the variations in hormone cycles, have not been explained. Methods: The present study used an electroencephalogram (EEG stress evaluation test, a physiology stress evaluation test, and the positive affect and negative affect scale (PANAS to evaluate the stress reactivity pattern and emotional state of women with PMS. Results: The results showed that women with PMS had higher negative affect and lower positive affect compared with controls. Moreover, under stressful conditions, the women with PMS had a higher alpha activity and a lower respiration rate than the controls. The differences in stress reactivity and emotional states between women with PMS and controls were based on a covariant analysis with menstrual cycle (luteal and follicular phases as the covariate. Conclusion: The results demonstrated that, compared with controls, women suffering from PMS have a continuous abnormality in emotional state and stress reactivity, which was independent of the menstrual cycle. Keywords: premenstrual syndrome, stress reactivity, emotion, EEG stress evaluation test, physiology stress evaluation test

  7. Bipolar disorder and Premenstrual Syndrome or Premenstrual Dysphoric Disorder comorbidity: a systematic review Comorbidade entre o Transtorno Bipolar e Síndrome Pré-menstrual ou Transtorno Disfórico Pré-menstrual: uma revisão sistemática

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    Patricia Carvalho Cirillo

    2012-12-01

    Full Text Available OBJECTIVE: This article aims to review the comorbidity of premenstrual syndrome (PMS or premenstrual dysphoric disorder (PMDD and bipolar disorder (BD, identify variables requiring further investigation and to remind physicians that special care is required for diagnosis and therapy. METHOD: A systematic review of articles published from 1987 to February 2012 was conducted in the Medline database with the following terms: (premenstrual syndrome OR premenstrual dysphoric disorder OR premenstrual AND (bipolar OR mania OR manic. Seventeen articles were analyzed. RESULTS: PMS and PMDD were most often comorbid among BD-II patients and vice versa. Moreover, patients with PMS or PMDD also have an increased risk of having BD-I. In addition, bipolar women susceptible to hormonal changes exhibit more severe symptoms, more frequent relapses and a worse therapeutic response. CONCLUSION: Future investigations should attempt to stabilize hormonal levels through the continuous use of contraceptives to target a reduction in symptom severity. In addition, psychiatrists should note menstrual period dates and compare symptom intensity between the luteal and follicular phases. Finally, PMS and PMDD patients should be studied separately.OBJETIVO: Esse artigo tem como objetivo revisar a comorbidade entre a Síndrome Pré-Menstrual (SPM ou Transtorno Disfórico Pré-Menstrual (TDPM e o Transtorno Bipolar (TB, identificar as variáveis que exigem uma investigação mais aprofundada e lembrar os médicos que as mulheres necessitam de cuidados especiais para diagnóstico e tratamento. MÉTODO: Foi realizada uma revisão sistemática de 1987 a fevereiro de 2012 através da base de dados Medline utilizando os seguintes descritores: (premenstrual syndrome OR premenstrual dysphoric disorder OR premenstrual AND (bipolar OR mania OR manic. Dezessete artigos foram analisados. RESULTADOS: Pacientes com SPM ou TDPM possuem comorbidade com TB-II com maior frequência e vice

  8. Comparing the Effects of Vitamin B1 and Calcium on Premenstrual Syndrome (PMS among Female Students, Ilam- Iran

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    Soheila Samieipour

    2016-09-01

    Full Text Available Background Premenstrual syndrome (PMS is a combination of physical, psychological and emotional symptoms that occur periodically before menstruation and disappear with the onset of menstruation. There are some therapeutic methods mostly according to the clinical trials that reduce the prevalence and intensity of symptoms of PMS by unknown mechanisms. This study aimed to investigate the effects of Calcium and vitamin B1 on Premenstrual syndrome among female students. Materials and Methods: This is a triple-blind clinical trial conducted on 210 female students living in dormitories of Ilam University of Medical Sciences who had PMS. PMS symptoms questionnaire was used to investigate the symptoms. Participants were assigned in 3 groups of 70 people with the following regimen: group 1 received one pill containing 100 milligrams vitamin B1, group 2 received Calcium pills and group 3 received placebo. The participants in all groups took medicines for 2 months and then reported the intensity of their symptoms by the questionnaire. The collected data was analyzed by descriptive and inferential statistics, using SPSS-16. Results: In groups receiving vitamin B1, Calcium and placebo, the intensity of physical and psychological symptoms as well as general symptoms of PMS had a remarkable reduction (P

  9. Premenstrual syndrome and perception of impact on sport performance from Brazilian indoor soccer athletes

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    Patrícia Aparecida Gaion

    2009-01-01

    Full Text Available This study’s objective was to verify the association between Premenstrual Syndrome (PMS and perceived impact on sport performance from Brazilian indoor soccer athletes. A total of 112 athletes were enrolled, with ages varying from 18 to 31years old, and who participated in the Brazilian Clubs Cup in 2007. The instruments used were: a self-reported sheet based on criteria from the American College of Obstetricians and Gynecologist (2000 for the diagnosis of PMS and a sport performance impact perception sheet, organized in a Likert scale with values ranging from 0 (“notaffected” to 3 (“extremely affected”. Data were analyzed using the Mann-Whitney test, Pearson’s chi-square and Poisson regression with robust variance. The prevalence of PMS was 47.32% and the perceived impact on sport performance for those with PMS was RP 1.71 (95%CI 1.23 to 2.38. The symptoms associated with sport performanceimpact were depression, irritability, breast tenderness, difficulty concentrating, back pain and tiredness. The intensity with which the athletes with PMS feel their performance affected during the premenstrual phase was significant in the “lowly affected “(RP 2.195%CI 1.26 to 3.55 and “extremely affected” (RP 3.5 95%CI 2.23 to 5.62 categories. Athletes with 6 to 9 symptoms presented higher risk (RP 3.20 95%CI 1.53 to 6.71 than athletes with 4 to 5 symptoms (RP 2.82 95%CI 1.32 to 6.05 or with 2 to 3 symptoms (RP 2.57 95%CI 1.25 to 5.30. In conclusion, the presence of PMS, the number and thekind of symptoms all exhibited associations with the sport performance impact perceived by Brazilian indoor soccer athletes.

  10. Femicomfort in the Treatment of Premenstrual Syndromes: A Double-Blind, Randomized and Placebo Controlled Trial

    Directory of Open Access Journals (Sweden)

    Shahin Akhondzadeh

    2010-06-01

    Full Text Available "nObjective:Premenstrual syndromes (PMS affecting 20-40% of women of reproductive age. The aim of this double blind and placebo controlled trial was to investigate whether femicofort a supplement contains Vitamin B6, Vitamin E and evening primrose oil could relieve symptoms of PMS. "nMethod: This was a randomized and double blind clinical trial. The trial was conducted between November 2009 and April March 2010. Women aged 20 to 45 years with regular menstrual cycles and experience of PMS symptoms (According to the current diagnostic criteria proposed by the American College of Obstetrics and Gynecology for at least 6 months were eligible for the study. Patients were randomized to receive femicomfort or placebo in a 1: ratio using a computer-generated code. The assignments were kept in sealed, opaque envelopes until the point of analysis of data. In this double-blind, patients were randomly assigned to receive capsule of femicomfort (Group A or capsule placebo for two menstrual cycles (cycles 3 and 4. The primary outcome measure was the Daily Symptom Report, a checklist of 17 premenstrual symptoms rated from 0 to 4 according to their severity throughout the menstrual cycle. Secondary outcome measure was Hamilton Depression Rating Scale (17-item. "nResults:Femicomfort at this dose was found to be effective in relieving symptoms of PMS. The difference between the femicomfort and placebo in the frequency of side effects was not significant. Conclusion: The results of this study indicate the efficacy of femicomfort in the treatment of PMS.

  11. Safety, efficacy, actions, and patient acceptability of drospirenone/ethinyl estradiol contraceptive pills in the treatment of premenstrual dysphoric disorder

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    Lesley L Breech

    2009-08-01

    Full Text Available Lesley L Breech, Paula K BravermanDivision of Adolescent Medicine, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USAAbstract: Premenstrual dysphoric disorder (PMDD is estimated to affect 3%–8% of reproductive age women. Multiple therapeutic modalities have been evaluated with varying efficacy for the associated somatic and mood symptoms. The majority of older studies had shown that oral contraceptive pills (OCs were most effective for the physical symptoms. However, newer OCs containing a novel progestin, drospirenone, have shown promise in alleviating both the somatic and affective/behavioral symptoms. This progestin, which is a derivative of spironolactone, has both antimineralocorticoid and antiandrogenic activity. A 24/4 formulation containing 20 µg of ethinyl estradiol has been found effective in randomized double-blind placebo-controlled trials utilizing established scales documenting symptoms associated with PMDD. Multiple studies have shown that drospirenone-containing OCs are safe without evidence of clinically adverse effects on carbohydrate metabolism, lipids, blood pressure, weight, serum potassium or increased thrombotic events compared to other low dose OCs. In addition, significant improvements have been demonstrated in acne, hirsutism, and fluid retention symptoms. Several open label studies demonstrated good patient compliance and reported satisfaction with the method. Because of the significant placebo effect demonstrated in the blinded placebo-controlled trials, additional large randomized placebo-controlled trials are needed to confirm the efficacy of the drospirenone OCs in the treatment of PMDD. However, this OC formulation appears to be a promising therapeutic modality.Keywords: drospirenone, premenstrual dysphoric disorder, premenstrual syndrome, oral contraceptive pill

  12. COMPARISON OF PREVALENCE OF PREMENSTRUAL SYNDROME IN SWIMMER AND NON-SWIMMER STUDENTS: A HISTORICAL COHORT STUDY

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    A Khademi

    2008-08-01

    Full Text Available "nA number of studies have examined the role of aerobic exercise and evidence suggests this may be an effective therapy for premenstrual syndrome (PMS. The aim of this study was to assess the PMS symptoms between swimmer and non-swimmer female students. Two hundred eighty subjects were studied. One hundred forty subjects were swimmers, while 140 were normal sedentary controls. Duration of swimming per week, and the length of exercise were asked from the case group. The predominant symptom of PMS was determined. PMS occurred in 36.2% and 22.8% of non-swimmers and swimmers, respectively (P = 0.00. The prevalence of premenstrual symptoms differ in the two group studied. There was no complaint about items asked in 35 (25% and 13 (9.9% of swimmers and non-swimmers, respectively (P = 0.000. In 11 (7.9% swimmers, there was a problem in more than 50% of items asked, whereas 48 (17.1 % non-swimmers had complaints in this range (P = 0.00. The prevalence of feeling more irritable, tend to eat more than usual or at irregular hours, easily distracted, restless behavior noticeable by others, feeling more angry, physical symptoms, change in mood without obvious reason, significant swelling in breasts, ankles, and abdomen, marked change in sexual desire, avoiding some social commitments, and decreasing desire to have communication with males were significantly lower in swimmers. Aerobic exercise has been found in epidemiologic studies to be associated with fewer reported premenstrual symptoms. Swimming is one of aerobic exercises which can be used in relation to this issue.

  13. Vestibular stimulation for management of premenstrual syndrome

    Science.gov (United States)

    Johny, Minu; Kumar, Sai Sailesh; Rajagopalan, Archana; Mukkadan, Joseph Kurien

    2017-01-01

    Objectives: The present study was undertaken to observe the effectiveness of vestibular stimulation in the management of premenstrual syndrome (PMS). Materials and Methods: The present study was an experimental study; twenty female participants of age group 18–30 years were recruited in the present study. Conventional swing was used to administer vestibular stimulation. Variables were recorded before and after vestibular stimulation and compared. Results: Depression and stress scores are significantly decreased after 2 months of intervention. Anxiety scores decreased followed by vestibular stimulation. However, it is no statistically significant. Serum cortisol levels significantly decreased after 2 months of intervention. WHOQOL-BREF-transformed scores were not significantly changed followed by the intervention. However, psychological domain score (T2) and social relationships domain score (T3) were increased followed by intervention. Systolic blood pressure was significantly decreased after 2 months of intervention. No significant change was observed in diastolic pressure and pulse rate. Pain score was significantly decreased after 2 months of intervention. Mini mental status examination scores and spatial and verbal memory score were significantly improved followed by intervention. Conclusion: The present study provides preliminary evidence for implementing vestibular stimulation for management of PMS as a nonpharmacological therapy. Hence, we recommend further well-controlled, detailed studies in this area with higher sample size. PMID:28250680

  14. Therapeutic Effect of Vitex Agnus Castus in Patients with Premenstrual Syndrome

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    Saadat Torabian

    2012-02-01

    Full Text Available Medical therapies have been widely used for premenstrual syndrome (PMS, but in all of them side effects are predominant. Herbal remedies rarely have side effects and people have more tendencies toward them than chemical therapies. In this study the therapeutic effect of Vitexagnuscastus on women who had the PMS, in comparison with placebo, were investigated. In this randomized, placebo-controlled, double-blind study, from134 selected patients 128 women suffered from PMS were evaluated (active 62, placebo 66.All patients answered to a self assessment questionnaire about their headache, anger, irritability, depression, breast fullness and bloating and tympani during the premenstrual period before the study. Forty drops of Vitexagnus extract or matching placebo, administrated for 6 days before mensesfor 6 consecutive cycles. Patients answered the self-assessment questionnaires after 6 menstrual cycles, again. Each item rated using a visual analogue scale (VAS. The mean age was 30.77 (SD=4.37 years in the active group and 30.89 (SD=4.02 years in the placebo group.Rank of variables had significantly difference in active and placebo group before and after the study (P<0.0001also we noticed significant differences on the use of VitexAgnus in comparison with placebo (P<0.0001.Vitexagnus can be considered as an effective and well tolerated treatment for the relief of symptoms of mild and moderate PMS.

  15. The premenstrual period and exacerbations in multiple sclerosis

    NARCIS (Netherlands)

    Zorgdrager, A; De Keyser, J

    2002-01-01

    The aim of this study was to assess whether an association exists between the premenstrual period and exacerbations of multiple sclerosis (MS). The subjects were 56 premenopausal patients with relapsing MS and a regular menstrual cycle. Data over the previous 2 years were gathered from a structured

  16. Pre-Menstrual Syndrome in Women with Down Syndrome

    Science.gov (United States)

    Mason, Linda; Cunningham, Cliff

    2009-01-01

    Background: Prevalence of pre-menstrual syndrome (PMS) may be higher in women with Down syndrome due to syndrome specific characteristics in biochemistry, psychopathology and lifestyle. Recognition of PMS may be difficult for women with intellectual disabilities and their carers. Method: A daily diary, used to diagnose PMS with typical women, was…

  17. Pre-Menstrual Syndrome in Women with Down Syndrome

    Science.gov (United States)

    Mason, Linda; Cunningham, Cliff

    2009-01-01

    Background: Prevalence of pre-menstrual syndrome (PMS) may be higher in women with Down syndrome due to syndrome specific characteristics in biochemistry, psychopathology and lifestyle. Recognition of PMS may be difficult for women with intellectual disabilities and their carers. Method: A daily diary, used to diagnose PMS with typical women, was…

  18. Comparing the effects of aerobic exercise and Foeniculum vulgare on pre-menstrual syndrome

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    Hassan Pazoki

    2016-03-01

    Full Text Available Introduction: Premenstrual syndrome (PMS has been identified by a number of psychological and physical symptoms which occur cyclically in the luteal phase of the menstrual cycle. The present study has been carried out to compare the effects of regular exercise and Foeniculum vulgare extract (fennel together and separately on PMS in high school girls. Materials and methods: In this randomized clinical trial 48 students aged 16–18 years were selected by filling the daily record of severity of problem questionnaire (DRSP-Q. The participants were divided into four equal groups: the first group received fennel, the second group had aerobic exercise, the third group received fennel along with exercise and the last group was control group without fennel and exercise. Participants filled DRSP-Q three times: the first menstrual cycle before the intervention, the first menstrual cycle after four weeks and finally the first menstrual cycle after eight weeks of intervention. Results: After 8 weeks of intervention the severity of PMS symptoms reduced significantly in experimental groups (fennel, exercise and fennel + exercise compared to control group (P < 0.05. Meanwhile, there were not any significant differences in age, body mass index, age at menarche, age at dysmenorrhea onset and duration of menstruation among the four groups. Discussions: The result of this study indicated that fennels and exercise could reduce the severity of premenstrual syndrome. In addition, fennel extract and exercise together seem to be more effective on symptoms of anxiety and depression compared with using them alone.

  19. Premenstrual syndrome: Symptomatic and diagnosed prevalence, dualistic treatment approach – A cross-sectional study in Ukraine

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    Edith Meszaros Crow

    2017-01-01

    Full Text Available Background: Diagnosing and treatment of premenstrual syndrome (PMS still pose a challenge in the routine medical practice which usually focuses on single pharmacological therapy. Recent research suggests that the combination of treatments including complementary alternative medicine (CAM therapies may be more beneficial. The objective of this study was to assess the percentage of diagnosed and nondiagnosed PMS/premenstrual dysphoric disorder (PMDD based on the presence of adequate symptoms and to compare population using hormonal or pharmaceutical agents versus CAM therapies. Methods: This is a cross-sectional study targeting sample population of 160 females of potentially reproductive age done in Ukraine between May 2014 and April 2015. Results: According to declared symptoms, 29% females versus 26% previously diagnosed by a medical professional qualify for “moderate/severe PMS,” P > 0.05. In 30% persons using pharmacological agents, major side effects, namely, nausea, insomnia, headache was caused by painkillers, contraceptives, and antidepressants. Only 37.5% of study population has been using CAM therapy methods to deal with the symptoms of PMS. Of these, 22% have achieved moderate degree in relief of the symptoms long term. Conclusions: We have concluded that when dealing with the burden of PMS/PMDD, the affected treatment-seeking women should have choice and access to the variety of therapies within integrative medicine (both conventional and nonconventional.

  20. Type 2 leprosy reaction with Sweet's syndrome-like presentation*

    Science.gov (United States)

    Chiaratti, Francielle Chiavelli; Daxbacher, Egon Luiz Rodrigues; Neumann, Antonielle Borges Faria; Jeunon, Thiago

    2016-01-01

    Leprosy is a chronic disease characterized by manifestations in the peripheral nerves and skin. The course of the disease may be interrupted by acute phenomena called reactions. This article reports a peculiar case of type 2 leprosy reaction with Sweet's syndrome-like features as the first clinical manifestation of leprosy, resulting in a delay in the diagnosis due to unusual clinical presentation. The patient had clinical and histopathological features reminiscent of Sweet's syndrome associated with clusters of vacuolated histiocytes containing acid-fast bacilli isolated or forming globi. Herein, it is discussed how to recognize type 2 leprosy reaction with Sweet's syndrome features, the differential diagnosis with type 1 leprosy reaction and the treatment options. When this kind of reaction is the first clinical presentation of leprosy, the correct diagnosis might be not suspected clinically, and established only with histopathologic evaluation. PMID:27438203

  1. Pyridoxine in the treatment of premenstrual syndrome: a retrospective survey in 630 patients.

    Science.gov (United States)

    Brush, M G; Bennett, T; Hansen, K

    1988-11-01

    We present a survey summarising the retrospective reports of the therapeutic effect of pyridoxine (vitamin B6) in 630 women suffering from premenstrual syndrome (PMS) who attended a PMS clinic during the period 1976-1983. The daily doses of pyridoxine hydrochloride varied from 40 to 100 mg early in the study and from 120 to 200 mg in the later period of the investigations. The response to treatment was recorded as good (no significant residual complaints) in 40 per cent or more of patients taking 100-150 mg pyridoxine daily and in 60 per cent of patients treated with 160-200 mg daily. Together with partial response (useful benefit but still some significant complaints), the positive effect of the treatment increased to 65-68 per cent and 70-88 per cent respectively. No symptoms consistent with a diagnosis of peripheral neuropathy were reported.

  2. Cyclical Changes in Calcium Metabolism across the Menstrual Cycle in Women with Premenstrual Dysphoric Disorder

    National Research Council Canada - National Science Library

    Thys-Jacobs, Susan; McMahon, Don; Bilezikian, John P

    2007-01-01

    ...: Our objective was to measure fluctuations and group differences in calcium-regulating hormones across the menstrual cycle in women with and without premenstrual dysphoric disorder (PMDD). Design...

  3. Beta-Arrestin1 Levels in Mononuclear Leukocytes Support Depression Scores for Women with Premenstrual Dysphoric Disorder

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    Farzana Alam

    2015-12-01

    Full Text Available Depression is very common in reproductive women particularly with premenstrual dysphoric disorder (PMDD, which is a severe form of premenstrual syndrome (PMS. Beta-arrestins were previously implicated in the pathophysiology, diagnosis and treatment for mood disorders. This study examined whether a measurement for beta-arrestin1 levels in peripheral blood mononuclear leukocytes (PBMC, could aid to distinguish between PMDD and PMS. Study participants (n = 25 were non-pregnant women between 18–42 years of age with the symptoms of PMS/PMDD, but not taking any antidepressants/therapy and at the luteal phase of menstruation. The levels of beta-arrestin1 protein in the PBMCs were determined by ELISA using human beta-arrestin1 kit. The beta-arrestin1 levels were compared with the Hamilton Depression Rating Scale scores among these women. The magnitude of the different parameters for Axis 1 mental disorders were significantly higher and beta arrestin1 protein levels in PBMCs were significantly lower in women with PMDD as compared to PMS women. The reduction in beta arrestin1 protein levels was significantly correlated with the severity of depressive symptoms. Beta-arrestin1 measurements in women may potentially serve for biochemical diagnostic purposes for PMDD and might be useful as evidence-based support for questionnaires.

  4. The interrelation between premenstrual syndrome and major depression: Results from a population-based sample

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    Weiss Carine

    2011-10-01

    Full Text Available Abstract Background Research about the relationship between premenstrual syndrome (PMS and major depression is limited. This study examined the relationship between moderate to severe PMS and major depression in a population-based sample of women of reproductive age. The objectives of the study were to assess the association between premenstrual syndrome and major depression, to analyse how PMS and major depression differ and to characterise the group of women who report both PMS and major depression. Methods Data were obtained from the Swiss Health Survey 2007. Included in the analysis was data from women under the age of 55 without hysterectomy and who answered the questions on PMS symptoms. The population-based sample consisted of 3518 women. Weighted prevalence rates were calculated and relative risk ratios for PMS, major depression and women who reported both PMS and major depression, were calculated with logistic multinominal logit regression. Results The prevalence of major depression was 11.3% in women screening positive for moderate PMS and 24.6% in women screening positive for severe PMS. Compared to women without any of these conditions, women who reported moderate to severe alcohol consumption had a lower risk for PMS. Women reporting use of antidepressants, and use of oral contraceptives had a higher risk for major depression compared to women without any of these conditions. Women reporting work dissatisfaction had a higher risk for PMS. A higher relative risk to report both PMS and major depression compared to women without PMS or major depression was related to factors such as high psychological distress, low mastery, psychotropic drug consumption, and low self-rated health. Conclusions The results suggested that women who suffer from both PMS and major depression are more impaired compared to women with only one disorder. The results further indicated that PMS and major depression are different disorders that can, however, co-occur.

  5. The phenomenology of premenstrual syndrome in female medical students: a cross sectional study

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    Magdy Hassan Balaha

    2010-04-01

    Full Text Available BACKGROUND: The premenstrual syndrome (PMS is particularly common in the younger age groups and, therefore represents a significant public health problem in young girls. This study aims to estimate the prevalence, severity, determinants of premenstrual syndrome (PMS and its impact among the female medical students in Al-Ahsa, Saudi Arabia. METHODS: This study was performed at the College of Medicine, King Faisal University, Saudi Arabia, from June through December 2009. It included 250 medical students. They filled different questionnaires covering American College of Obstetrics and Gynecology (ACOG criteria to diagnose PMS, demographic and reproductive factors, physical activity and mental condition. Regression analysis was conducted for all the predictors. RESULTS: PMS was diagnosed in 35.6% of cases, distributed as 45% mild, 32.6% moderate and 22.4% severe. There were significant trends for older age, rural residence, family income and family history of PMS. The dominant limited activity was concentration in class (48.3%. Limitations of activities were significantly more frequent among severe cases. The preva lence of anxiety and depression was statistically more evident in the PMS group. Regression analysis revealed that, PMS was significantly associated with older age groups, rural residence, lower age at menarche, regularity of menses and family history. CONCLUSION: PMS is a common problem in young Saudi students in Al Ahsa. Severe PMS was associated with more impairment of daily activities and psychological distress symptoms. Older student age, rural residence, earlier age of menarche, regular cycles and positive family history are possible risk factors for PMS.

  6. The Effects of Mindfulness-Based Cognitive Therapy on Depression and Anxiety in Women with Premenstrual Syndrome

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    Faeze Panahi

    2016-01-01

    Full Text Available Objective. Little research has been done regarding the role of psychotherapy in the treatment of Premenstrual Syndrome (PMS. The aim of this study was to examine the effect of mindfulness-based cognitive therapy (MBCT on the PMS symptoms and depression and anxiety symptoms in women with PMS. Design. In a randomized controlled trial, a total of 60 students at Mazandaran University with mild to moderate PMS who had depressive symptoms (Beck depression scores 16–47 were randomly allocated to either an experimental (n=30 or a control (n=30 group. The experimental group received MBCT in eight group sessions (120 min each over 8 weeks. The control group received no intervention. All participants completed the Premenstrual Assessment Scale (PAS, Beck Depression Inventory (BDI, and Beck Anxiety Inventory (BAI at the beginning and the end of the study. Repeated-measure ANOVA was used to analyze the data. Results. At the end of study, the experimental and control groups showed the following scores, respectively (mean ± SD: depression, 15.73±6.99 and 25.36±7.14; anxiety, 16.96±7.78 and 26.60±9.38; and total PAS, 42.86±8.02 and 58.93±8.47. MBCT improved depression and anxiety symptoms and total PAS score. Conclusion. MBCT intervention is acceptable and potentially beneficial in women with PMS symptoms. Psychotherapy should be considered as a treatment option for mild to moderate PMS in women with depressive symptoms.

  7. The premenstrual phase and reactions to aversive events: a study of hormonal influences on emotionality.

    NARCIS (Netherlands)

    Goozen, van St.H.M.; Frijda, N.H.; Wiegant, V.M.; Endert, E.; Poll, van de N.E.

    1996-01-01

    Fifty-eight normal cycle, healthy women were confronted with an aversive, anger-provoking situation in the laboratory. Eighteen women were tested in their follicular phase. A further 40 women were tested in the premenstrual phase, half of whom reported suffering from complaints of premenstrual emoti

  8. Changes in functioning of mesolimbic incentive processing circuits during the premenstrual phase

    NARCIS (Netherlands)

    Ossewaarde, L.; Wingen, G.A. van; Kooijman, S.C.; Backstrom, T.; Fernandez, G.S.E.; Hermans, E.J.

    2011-01-01

    The premenstrual phase of the menstrual cycle is associated with marked changes in normal and abnormal motivated behaviors. Animal studies suggest that such effects may result from actions of gonadal hormones on the mesolimbic dopamine (DA) system. We therefore investigated premenstrual changes in r

  9. Personality Traits of Suicidality Are Associated with Premenstrual Syndrome and Premenstrual Dysphoric Disorder in a Suicidal Women Sample.

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    Déborah Ducasse

    Full Text Available Both Premenstrual Syndrome (PMS and Premenstrual Dysphoric Disorder (PMDD might increase the risk of suicidal behavior. The aim of this study was to assess the relationship between personality dimensions specifically involved in suicidal vulnerability and PMS/PMDD.We collected data from 232 women consecutively hospitalized after a suicide attempt. We examined the relationship between impulsivity, aggressiveness/hostility, hopelessness, trait anger, affect intensity, emotional lability, and PMS/PMDD. Notably, we created an algorithm from the shortened Premenstrual Assessment form in order to assess PMDD status.The proportions of PMS and PMDD among female suicide attempters were 50% and 23% respectively. Women with PMS or PMDD were more likely to endorse most of these personality traits to than those without even after controlling for potential confounders. We found an impulsive-aggressive pattern of personality in women with PMS or PMDD, independently from the time of the menstrual cycle. Interestingly, trait anger remained associated with both PMS and PMDD independently of every other personality traits. The higher the anger level, the higher the risk was to suffer from both PMS and PMDD.This study demonstrates a strong, independent association between PMS/PMDD and trait anger among a representative sample of female suicide attempters. It is of major interest for clinicians in view of addressing a substantial public health problem among women of reproductive age.

  10. Assessment of starch dietary regimen regarding pre-menstrual syndrome among high school students in Sari during 2007

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    K. Abedian Kasgari

    2008-01-01

    Full Text Available AbstractBackground and Purpose: Pre-menstrual syndrome (PMS is one of the abnormalities associated with pre-menstrual cycles. Approximately 85% to 97% of women are suffering from psycho-somatic of physiological and behavioral symptoms from PMS, prior to menstruation. The most common PMS symptoms include: flatulence, stress anxiety, breast tenderness, depression, fatigue, unknown irritability, anger, poor concentration, and some degree in extremities edema. There are several therapeutic methods for PMS such as: oral contraceptive pills, GnRH antagonisms, diazole, use of Calcium and vitamin supplements, and dietary modification in which there is a controversy regarding type of diet. We assessed the effect of third- hour starch dietary regimen on pre-menstrual syndrome among high school students.Materials and Methods: This randomized quasi- experimental study was performed on students in grade 2 and 3 in Private and Governmental high schools in Sari. The sample size was calculated using randomize numbers table (478 participants. A questionnaire composed of two parts was prepared. The first part included demographic characteristics, while the second part consisted of data related to history of menstrual cycle, pervious diseases and use of drugs. The symptoms of PMS were assessed at the beginning of the study and also at the end of the first, second and third month after beginning of the third-hours starch regimen. Data was gathered by self-reporting technique, analyzed by descriptive and comprehensive statistical techniques.Results: The age range of participants was 14 to 19 years of age (16.891.12. The mean of menstrual cycle was 28.872.1 days, and the mean of menstrual duration was 6.321.8. PMS symptoms score was 12.858.01 prior to dietary regimen, and at the end of one, two and three months, following dietary regimen in-take were 11.037.59, 12.477.79 and 11.136.71 respectively. This study indicated that there was significant

  11. Premenstrual Dysphoric Disorder (PMDD): Different from PMS?

    Science.gov (United States)

    ... The cause of PMDD isn't clear. Underlying depression and anxiety are common in both PMS and PMDD, so ... before trying one. Diet and lifestyle changes. Regular exercise often ... smoking may ease symptoms, too. Getting enough sleep and using relaxation ...

  12. The Relationship Between Premenstrual Syndrome and Food Patterns in University Student Girls

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    Darabi

    2014-12-01

    Full Text Available Background Premenstrual syndrome (PMS is a group of disorders that many girls and women suffer from. It is well known that an appropriate diet as well as environmental factors plays a major role in quality of life. Objectives This study evaluates food patterns for university student girls who suffer from PMS and are healthy. Materials and Methods Eighty-six university student girls from Ahvaz Jundishapur University of Medical Sciences participated in the survey and PMS was diagnosed using the diagnostic criteria of the American College of Obstetricians and Gynecologists. They completed a daily symptom-rating questionnaire for PMS symptoms. The score of categorical symptoms (mood-emotional and gastrointestinal disorders, pain, fatigue-focus, and other disorders were determined separately. Student food pattern was determined according to the Iranian food pyramid. The correlation between symptom scores and food group servings was determined by the Pearson correlation coefficient. Results The score for each categorical symptom showed significant differences between healthy and students who suffered from PMS (P < 0.001. A significant negative relationship was observed between milk consumption and pain score (P = 0.038, r = -0.224, and between total dairy consumption and pain score (P = 0.019, r = -0.253. Total disorder scores showed a significant negative relationship with total dairy product (P = 0.024, r = -0.243. Conclusions The results of the survey indicate that PMS symptoms are related to consuming less milk or dairy products. Therefore, an appropriate intake of foods according to standard food patterns (like the Iranian food pyramid is recommended.

  13. Estudo populacional de síndrome pré-menstrual Population study of premenstrual syndrome

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    Celene Maria Longo da Silva

    2006-02-01

    -sectional population-based study, involving 1,395 women aged 15 to 49 years old in a medium-sized municipality in Southern Brazil, carried out in 2003. Questionnaires were applied to measure the prevalence of premenstrual syndrome by means of a score based on five premenstrual symptoms that interfered with family life or led to absence from work or school. Associations with socioeconomic, demographic and behavioral variables were investigated. Self-reported syndrome was investigated with regard to its sensitivity and specificity, taking the score as the gold standard. The statistical analyses performed were Pearson chi2, Mantel-Haenszel and Poisson regression, with Kappa coefficients to verify the concordance of the responses. RESULTS: The obtained prevalence was 25.2% (95% CI: 22.5-27.9 and the self-reported prevalence was 60.3% (95% CI: 57.4-63.3. The principal premenstrual symptoms found were: irritability, abdominal discomfort, nervousness, headache, fatigue and breast pain; all of these showed prevalence of over 50%. Higher risk was presented by women of higher socioeconomic level, better schooling level, aged under 30 years and with white skin color. Psychotropic drug users and women who were not using any hormonal contraceptive presented higher prevalence of the syndrome. The sensitivity of the test was 94%, specificity 51% and accuracy 62%. CONCLUSIONS: A high prevalence of premenstrual syndrome was found. Even though the women's perception of the syndrome was higher than the result measured by the symptom score, one quarter of the women presented this health problem.

  14. Comparison the effects of Ginger and Curcumin in treatment of premenstrual syndrome

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    Samira khayat

    2015-07-01

    Full Text Available Background: Most women at reproductive ages experience the premenstrual syndrome (PMS. Different methods have been suggested for the treatment of this syndrome and one of them is using herbal medicine. This study was carried out to evaluate the effects of ginger and curcumin on severity of symptoms of PMS. Materials and Methods: In this double-blind clinical trial, 105 students with PMS symptoms were randomly assigned to ginger, curcumin and placebo groups. Participants received two capsules daily from seven days before menstruation to three days after menstruation for three cycles and they recorded severity of the symptoms by Daily Record of Severity of Problems (DRSP questionnaire. Data of before interventions and 1, 2 and 3 months after interventions were analyzed by repeated measurement ANOVA and indepented t-test. SPSS-18 software was used for analyses and P<0/05 was considered significant. Results: The mean of PMS symptoms severity were similar in three groups before the intervention [( 110/2±30/7 in ginger group, 103/6±39/1 in curcumin group and106/7±44/65 in placebo group p=0/79], but after interventions there were significant differences between groups [(47/06 ±33/4 in ginger group, 29/74±11/6 in curcumin group and106±48/7 in placebo group P<0/0001]. Also, there was a significant difference between effects of curcumin and ginger (P=0/008. Conclusion: Ginger and curcumin are effective in reduction of severity of psychological, physical and behavioral symptoms of PMS and the effect of curcumin is more than ginger. Results of present study suggest curcumin and ginger as treatment for PMS.

  15. Sweet food improves chronic stress-induced irritable bowel syndrome-like symptoms in rats.

    Science.gov (United States)

    Rho, Sang-Gyun; Kim, Yong Sung; Choi, Suck Chei; Lee, Moon Young

    2014-03-07

    To investigate whether palatable sweet foods have a beneficial effect on chronic stress-induced colonic motility and inflammatory cytokines. Adult male rats were divided into 3 groups: control (CON, n = 5), chronic variable stress with chow (CVS-A, n = 6), and chronic variable stress with chow and sweet food (CVS-B, n = 6). The rats were fed standard rodent chow as the chow food and/or AIN-76A as the sweet food. A food preference test for AIN-76A was performed in another group of normal rats (n = 10) for twelve days. Fecal pellet output (FPO) was measured for 6 wk during water bedding stress in the CVS groups. The weight of the adrenal glands, adrenocorticotropic hormone (ACTH) and corticosterone levels in plasma were measured. The expression levels of transforming growth factor-β, interleukin (IL)-2, and interferon-gamma (IFN-γ) were measured in the distal part of colonic tissues and plasma using Western blot analysis. In sweet preference test, all rats initially preferred sweet food to chow food. However, the consumption rate of sweet food gradually decreased and reduced to below 50% of total intake eight days after sweet food feeding. Accumulated FPO was higher in the CVS-A group compared with the CVS-B group over time. All stress groups showed significant increases in the adrenal to body weight ratio (CVS-A, 0.14 ± 0.01; CVS-B, 0.14 ± 0.01) compared with the control group (0.12 ± 0.01, P colon compared to the control group, whereas this effect was significantly attenuated in the CVS-B group. These results suggest that concurrent sweet food ingestion during CVS might have an effect on the reduction of stress-induced colonic hyper-motility and pro-inflammatory cytokine production in rats.

  16. Effect of '61-points relaxation technique' on stress parameters in premenstrual syndrome.

    Science.gov (United States)

    Dvivedi, Jyoti; Dvivedi, Sanjay; Mahajan, K K; Mittal, Sunita; Singhal, Anil

    2008-01-01

    Premenstrual Syndrome is a psychoneuroendocrine stress related disorder and more than 300 treatment modalities for PMS show that the existing remedies have not provided satisfactory help to relieve PMS. 61-points relaxation exercise (61-PR), a relatively less known hatha yoga technique, is a successful means of stress relaxation and is expected to relieve PMS as well. The present study was conducted on 50 clinically healthy women volunteers who were in their reproductive age group and in their premenstrual period, from which a control group (n = 20) and a PMS group (n = 30) based on the symptoms were identified. In both groups basal heart rate (HR/min), systolic (SBP; mmHg) and diastolic blood pressure (DBP; mmHg), electromyogram (EMG; mV), electrodermal galvanic activity (EDG; microv), respiratory rate (RR/min) and peripheral temperature (T; degrees F) were recorded and the subjects were taken through a guided 61-PR. The symptoms and parameters were re-recorded after the 61-PR. In control group, the basal HR was 82.06 +/- 8.07, SBP 111.95 +/- 8.23, DBP 76.8 +/- 6.42, EMG 4.08 +/- 2.99, EDG 9.77 +/- 3.29, RR 15.60 +/- 3.77 and T was 97.86 +/- 0.63. After 10 minutes of 61-PR, HR (77.27 +/-10.85, P 0.05) rose significantly. In the PMS group, the basal HR was 90.61 +/- 8.46, SBP 122.5 +/- 11.52, DBP 83.53 +/- 8.26, EMG 5.79 +/-2.75, EDG 13.14 +/- 6.54, RR 19.13 +/- 3.76 and T was 93.43 -/+ 5.29. After 10 minutes of 61-PR, HR (75.58 +/- 10.11, P relaxation. 61-PR is effective in providing relief from PMS and may be a useful adjuvant to medical therapy of PMS and other stress disorders.

  17. The phenomenology of premenstrual syndrome in female medical students: a cross sectional study

    OpenAIRE

    Magdy Hassan Balaha; Mostafa Abd El Monem Amr; Mohammed Saleh Al Moghannum; Nouria Saab Al Muhaidab

    2010-01-01

    BACKGROUND: The premenstrual syndrome (PMS) is particularly common in the younger age groups and, therefore represents a significant public health problem in young girls. This study aims to estimate the prevalence, severity, determinants of premenstrual syndrome (PMS) and its impact among the female medical students in Al-Ahsa, Saudi Arabia. METHODS: This study was performed at the College of Medicine, King Faisal University, Saudi Arabia, from June through December 2009. It included 250 medi...

  18. Deregulation of Fas ligand expression as a novel cause of autoimmune lymphoproliferative syndrome-like disease.

    Science.gov (United States)

    Nabhani, Schafiq; Ginzel, Sebastian; Miskin, Hagit; Revel-Vilk, Shoshana; Harlev, Dan; Fleckenstein, Bernhard; Hönscheid, Andrea; Oommen, Prasad T; Kuhlen, Michaela; Thiele, Ralf; Laws, Hans-Jürgen; Borkhardt, Arndt; Stepensky, Polina; Fischer, Ute

    2015-09-01

    Autoimmune lymphoproliferative syndrome is frequently caused by mutations in genes involved in the Fas death receptor pathway, but for 20-30% of patients the genetic defect is unknown. We observed that treatment of healthy T cells with interleukin-12 induces upregulation of Fas ligand and Fas ligand-dependent apoptosis. Consistently, interleukin-12 could not induce apoptosis in Fas ligand-deficient T cells from patients with autoimmune lymphoproliferative syndrome. We hypothesized that defects in the interleukin-12 signaling pathway may cause a similar phenotype as that caused by mutations of the Fas ligand gene. To test this, we analyzed 20 patients with autoimmune lymphoproliferative syndrome of unknown cause by whole-exome sequencing. We identified a homozygous nonsense mutation (c.698G>A, p.R212*) in the interleukin-12/interleukin-23 receptor-component IL12RB1 in one of these patients. The mutation led to IL12RB1 protein truncation and loss of cell surface expression. Interleukin-12 and -23 signaling was completely abrogated as demonstrated by deficient STAT4 phosphorylation and interferon γ production. Interleukin-12-mediated expression of membrane-bound and soluble Fas ligand was lacking and basal expression was much lower than in healthy controls. The patient presented with the classical symptoms of autoimmune lymphoproliferative syndrome: chronic non-malignant, non-infectious lymphadenopathy, splenomegaly, hepatomegaly, elevated numbers of double-negative T cells, autoimmune cytopenias, and increased levels of vitamin B12 and interleukin-10. Sanger sequencing and whole-exome sequencing excluded the presence of germline or somatic mutations in genes known to be associated with the autoimmune lymphoproliferative syndrome. Our data suggest that deficient regulation of Fas ligand expression by regulators such as the interleukin-12 signaling pathway may be an alternative cause of autoimmune lymphoproliferative syndrome-like disease. Copyright© Ferrata Storti

  19. The Association between Premenstrual Syndrome and Physical Activity and Aerobic Power in Female High School Students

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    Sabaei Yekta

    2015-04-01

    Full Text Available Objective: The purpose of this study was to investigate the relationship between premenstrual syndrome (PMS and physical activity, aerobic power, and anaerobic power in female high school students. Materials and Methods: A total of 367 female high school students were selected randomly from district 5 of Tehran. Among them, 40 students who had the highest PMS score and all the inclusion criteria of the study were selected as subjects. The level of physical activity was assessed using the Baecke Physical Activity Questionnaire and PMS was assessed using a self-report questionnaire. Aerobic power was assessed using submaximal 1-mile track jog test. Pearson’s correlation coefficient was used for analyzing the relationship between variables. Results: The results indicated a significant negative correlation between PMS and physical activity (r = -0.86 and P < 0.05 and aerobic power (r = -0.71 and P < 0.05. Conclusion: Based on the findings, it seems that regular physical activity, especially aerobic activities, can be effective in reducing the symptoms of PMS.

  20. Chronic periodontitis as an etiology of sleep disturbances and premenstrual syndrome (PMS

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    Haryono Utomo

    2007-03-01

    Full Text Available It is obvious that sleep disturbances may induced by acute pulpal or periodontal pain. Other causes of sleep disturbances which also termed as sleep dysfunction, or insomnia, according to the patient has to be treated by physician. Nevertheless, in a case report, surprisingly, periodontal treatment relieved sleep disturbances and premenstrual syndrome (PMS. Coincidentally, women also more vulnerable to sleep disturbances and periodontal disease. It is also interesting that the exact etiology of PMS is still unknown, and 80% women who suffered from PMS also experience sleep disturbances. Recently, there has been increasing numbers of literatures and evidence-based cases linking periodontal disease to systemic diseases. However, systemic effects of periodontal disease that lead to PMS which associated with sleep disturbances are rarely discussed. Several mechanisms had been proposed to involve in these symptoms: female sexual hormonal imbalance, stimulation of the hypothalamic-pituitary-adrenal axis (HPA-axis and neurogenic switching mechanism. In addition, as estrogen makes women more susceptible to stress, it worsen the symptoms. The glucocorticoid hormones synthesized upon stimulation of the HPA-axis, either by stress or pro-inflammatory cytokines, may disrupt the sleep-wake cycle; and also create estrogen dominance. The aim of this study is to propose the etiopathogenesis of PMS which associated with sleep disturbances that may be related to chronic periodontitis. Since in this case report scaling and curettage resulted in the disappearing of PMS and sleep disturbances; the conclusion is that chronic periodontal disease may act as one of the etiologies of PMS and sleep disturbance.

  1. Affective disturbance associated with premenstrual dysphoric disorder does not disrupt emotional modulation of pain and spinal nociception.

    Science.gov (United States)

    Rhudy, Jamie L; Bartley, Emily J; Palit, Shreela; Kuhn, Bethany L; Kerr, Kara L; Martin, Satin L; DelVentura, Jennifer L; Terry, Ellen L

    2014-10-01

    In healthy individuals, emotions modulate pain and spinal nociception according to a valence linear trend (ie, pain/nociception is highest during negative emotions and lowest during positive emotions). However, emerging evidence suggests that emotional modulation of pain (but not spinal nociception) is disrupted in fibromyalgia and disorders associated with chronic pain risk (eg, major depression, insomnia). The present study attempted to extend this work and to examine whether women with premenstrual dysphoric disorder (PMDD), a cyclical syndrome associated with debilitating affective symptoms during the late-luteal (premenstrual) phase of the menstrual cycle, is also associated with disrupted emotional modulation of pain. To do so, an affective picture-viewing procedure was used to study emotional modulation of pain and spinal nociception in 14 women with PMDD and 14 control women during mid-follicular, ovulatory, and late-luteal phases of the menstrual cycle (verified by salivary hormone levels and luteinizing hormone tests). At each phase, mutilation, neutral, and erotic pictures were presented to manipulate emotion. During picture viewing, suprathreshold electrocutaneous stimuli were presented to evoke pain and the nociceptive flexion reflex (NFR; a physiological measure of spinal nociception). Statistically powerful linear mixed model analyses confirmed that pictures evoked the intended emotional states in both groups across all menstrual phases. Furthermore, emotion modulated pain and NFR according to a valence linear trend in both groups and across all menstrual phases. Thus, PMDD-related affective disturbance is not associated with a failure to emotionally modulate pain, suggesting that PMDD does not share this pain phenotype with major depression, insomnia, and fibromyalgia.

  2. Ethinyl Estradiol-Drospirenon Versus Vitex Agnus-Castus Extract in Efficacy of the Treatment of Premenstrual Syndrome

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    Mustafa Kaplanoglu

    2014-12-01

    Full Text Available Aim: The premenstrual syndrome (PMS, which causes emotional and physical symptoms, is a common problem in reproductive age women. Several treatment modalities has been used in PMS. But controversial results has been observed in treatment . The present study was performed to compare vitex agnus castus (VAC and ethinyl estradiol-drospirenone (EE-Drs in the treatment of PMS. Material ve Method: It was a prospective, randomised, placebo-controlled study carried out in our clinic. A total of 120 patients were enrolled and randomly assigned to EE-Drs, VAC group or placebo group. Eligible patients were treated with EE-Drs, VAC extract and placebo for consecutive three cycles. Symptoms were documented with PMS diary (PMSD. Main efficacy variable was the reduction percentage of 15 symptom score documented in PMSD during the luteal phase of the third treatment cycle. Visual Anolog Scale (VAS was used in assessment of PMS semptoms. Results: After the treatment, there was statistically significant difference between the groups for anxiety (p

  3. Breast Magnetic Resonance Imaging Findings in Women Treated with Toremifene for Premenstrual Mastalgia

    Energy Technology Data Exchange (ETDEWEB)

    Oksa, S. (Dept. of Obstetrics and Gynecology, Satakunta Central Hospital, Pori (Finland)); Parkkola, R. (Dept. of Radiology, Univ. Hospital of Turku, Turku (Finland)); Luukkaala, T.; Maeenpaeae, J. (Medical School, Univ. of Tampere, Tampere (Finland))

    2009-11-15

    Background: Toremifene, a selective estrogen receptor modulator, has been shown to be effective in alleviating premenstrual breast pain. However, the exact mechanism by which toremifene and related compounds work in premenstrual mastalgia is poorly understood. Purpose: To find out if the effect of toremifene on breast would be detectable with dynamic magnetic resonance imaging (MRI). Material and Methods: This randomized, double-blind crossover study was performed on women suffering from marked premenstrual mastalgia. Ten women were randomized to receive either toremifene (20 mg) or placebo from cycle day 15 until next menstruation for three menstrual cycles. After a washout period, the treatment was crossed over for three additional cycles. The MRI evaluations were performed premenstrually at the end of each treatment phase. Breast pain and quality-of-life scores were collected from one baseline cycle and from all the treatment cycles. Results: Nine patients were evaluable for this analysis. Both the enhancement ratio and the maximum slope of enhancement tended to be smaller during the toremifene cycles as compared to placebo. On the left side, the difference in the maximum slope of enhancement between toremifene and placebo was statistically significant (median 5.150 [range 3.7-6.7] and 6.500 [range 4.9-9.5], respectively; P=0.047). T2 relaxation times as well as breast pain and quality-of-life scores were inconsistent. Conclusion: Use of toremifene is associated with measurable changes in dynamic breast MRI findings in women with cyclic breast pain

  4. The prevalence of premenstrual dysphoric disorder in a randomly selected group of urban and rural women

    NARCIS (Netherlands)

    Gehlert, S.; Song, I. H.; Chang, C. -H.; Hartlage, S. A.

    2009-01-01

    Background. Premenstrual dysphoric disorder (PMDD) was included as a provisional diagnostic category in the appendices of Diagnostic and Statistical Manual of Mental Disorders (DSM)-III-R (then called late luteal phase dysphoric disorder) and remained as an appendix in DSM-IV. Our study aimed to det

  5. Prevalência de síndrome pré-menstrual em atletas Prevalence of premenstrual syndrome in athletes

    Directory of Open Access Journals (Sweden)

    Patrícia Aparecida Gaion

    2010-02-01

    Full Text Available A síndrome pré-menstrual (SPM é um conjunto de sintomas emocionais e físicos que afeta negativamente as atividades diárias das mulheres durante o período pré-menstrual. Embora seja um tema bastante estudado na população em geral, existe uma lacuna na literatura a respeito da presença de SPM em atletas. Dessa forma, o objetivo do estudo foi analisar a prevalência de SPM em atletas. Foi desenvolvido um estudo do tipo inquérito, com 57 atletas, com idade entre 18 e 47 anos, de 11 modalidades esportivas. Para identificar a presença de SPM, utilizou-se uma ficha autoaplicável baseada nos critérios do American College of Obstetricians and Gynecologists (ACOG, 2000; a confirmação diagnóstica foi feita através do preenchimento de um diário de sintomas durante dois ciclos menstruais consecutivos (baseado no ACOG, 2000. Para análise dos dados utilizou-se teste de Shapiro-Wilk e teste exato de Fisher, adotando P The premenstrual syndrome (PMS is a set of emotional and physical symptoms that adversely affects the daily activities of women during the pre-menstrual period. Despite being a theme quite discussed in the general population, there is still a gap in the literature concerning the presence of PMS in athletes. Thus, the objective of the study was to analyze the prevalence of PMS in athletes. An inquiry study with 57 athletes age range of 18 and 47 years from 11 sport modalities was developed. A self-applicable sheet based on the American College of Obstetricians and Gynecologists criteria (ACOG, 2000 was used to identify the presence of PMS ; the diagnostic confirmation was performed through the answer of a symptoms diary during two consecutive menstrual cycles (based on ACOG, 2000. Shapiro Wilks test and Fisher's exact test, adopting a P<0.05 were used for the data analysis. The prevalence of PMS retrospectively estimated was of 68% while the estimated prevalence through the follow-up with the diaries was of 48%. Breast soreness

  6. Repercussões do transtorno disfórico pré-menstrual entre universitárias Effects of premenstrual dysphoric disorder among college students

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    Valéria Conceição Passos de Carvalho

    2009-01-01

    Full Text Available INTRODUÇÃO: O transtorno disfórico pré-menstrual (TDPM é uma variante mais grave da síndrome pré-menstrual que apresenta a oscilação do humor como fator mais perturbador e debilitante, repercutindo na qualidade de vida das mulheres em idade reprodutiva. O objetivo deste estudo foi identificar as principais repercussões físicas e emocionais causadas pela TDPM entre universitárias de Fisioterapia. MÉTODO: Estudo do tipo corte transversal, descritivo e analítico, realizado no período de agosto a dezembro de 2008 em 259 universitárias. Os instrumentos utilizados para a realização desta pesquisa foram: um questionário contendo questões socioeconômicas, o Questionário de Sintomas Menstruais (Menstrual Symptom Questionnaire, MSQ, a escala de autoavaliação de síndrome de transtorno pré-menstrual de Steiner e o Questionário de Autoavaliação da Escala de Hamilton para Depressão. A análise estatística foi descritiva e analítica, sendo utilizado o teste qui-quadrado ou o teste exato de Fisher, sendo que todas as conclusões foram tomadas ao nível de significância de 5%. RESULTADOS: Encontramos alta prevalência de repercussões somáticas e emocionais. Através dos sinais e sintomas pesquisados pelo MSQ entre as portadoras de TDPM, observou-se uma associação do transtorno com os sintomas depressivos (p = 0,048. Os demais sintomas como ansiedade, labilidade de humor, sintomas somáticos, habilidade para realizar tarefas e dor não apresentaram correlação. CONCLUSÃO: O TDPM provocou desconforto físico e emocional e revelou uma correlação significativa com os sintomas depressivos, sugerindo tratar-se de uma expressão clínica de transtorno de humor.INTRODUCTION: Maternal premenstrual dysphoric disorder (PMDD is a severe variant of premenstrual syndrome in which mood swings is the most disturbing and debilitating symptom, affecting the quality of life of women of reproductive age. The objective of this study was to

  7. Ansiedad y diagnóstico del síndrome premenstrual (SPM

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    CARMEN BORRÁS SANSALONI

    2001-01-01

    Full Text Available La falta de una definición clara y unánime del trastorno constituye uno de los principales problemas metodológicos en la evaluación del síndro m e premenstrual (SPM, dificultando enormemente la diferenciación entre los denominados cambios premenstruales negativos (CPM- y el verdadero síndrome premenstrual (SPM. Algunos autores, con el objeto de solucionar este problema, han propuesto una serie de criterios para el correcto diagnóstico del SPM, criterios que hacen referencia a síntomas tanto emocionales como comportamentales relacionados con la fase premenstrual del ciclo ovárico y cuya severidad interfiere significativamente en la vida cotidiana de las mujeres que los padecen No obstante, por una parte, algunos autores han señalado que dichos criterios diagnósticos se refieren a una manifestación ideal del trastorno y, por otra, numerosos estudios han demostrado que el patrón general de ansiedad constituye uno de los principales factores implicados en el padecimiento del SPM. En el presente trabajo, realizado con una muestra de 133 mujeres se analiza la posible relación entre el patrón general de ansiedad así como de las respuestas emocionales manifestadas en las diferentes fases del ciclo menstrual y los criterios diagnósticos del SPM.

  8. Effects of fentanyl on serotonin syndrome-like behaviors in rats.

    Science.gov (United States)

    Kitamura, Sonoe; Kawano, Takashi; Kaminaga, Satomi; Yamanaka, Daiki; Tateiwa, Hiroki; Locatelli, Fabricio M; Yokoyama, Masataka

    2016-02-01

    Emerging evidence from case reports suggests that fentanyl may precipitate potentially life-threatening serotonin syndrome in patients taking serotonergic drugs. However, the underlying mechanism of the association between serotonin syndrome and fentanyl remains under investigation. We therefore investigated the pharmacological effects of an analgesic dose of fentanyl (0.2 mg/kg) injected subcutaneously (s.c.) on serotonergic toxicity-like responses in rats. Rats were s.c. injected with 0.75 mg/kg 8-OH-DPAT, a full 5-HT1A agonist, as an animal model of serotonin syndrome. The 8-OH-DPAT-treated rats showed well-characterized serotonin syndrome-like behaviors (low body posture, forepaw treading), hyperlocomotion, and decreased body temperature. Rats injected s.c. with fentanyl alone showed no significant changes in any of the parameters measured, while concomitant administration of fentanyl + 8-OH-DPAT resulted in exaggerated 8-OH-DPAT-induced serototoxic responses. A separate dose-response experiment showed that the serototoxic effect of fentanyl was dose-dependent. Pretreatment with naloxone [2.0 mg/kg, intraperitoneal (i.p.) injection], an opioid receptor antagonist, failed to antagonize the fentanyl-induced exaggerated serotonin syndrome-like behaviors. In contrast, pretreatment with WAY-100653, a serotonin 5-HT1A receptor antagonist (0.5 mg/kg, i.p. injection) completely inhibited all responses. Our findings provide preclinical proof-of-concept that an analgesic dose of fentanyl enhances serotonin toxicity, likely via its serotonin-reuptake inhibitory activity, independently of interaction with the opioid receptors.

  9. Effect of curcumin on serum brain-derived neurotrophic factor levels in women with premenstrual syndrome: A randomized, double-blind, placebo-controlled trial.

    Science.gov (United States)

    Fanaei, Hamed; Khayat, Samira; Kasaeian, Amir; Javadimehr, Mani

    2016-04-01

    Premenstrual syndrome (PMS) is a variety of physical, mental, and behavioral symptoms that start during the late luteal phase of the menstrual cycle, and the symptoms disappear after the onset of menses. Serum brain-derived neurotrophic factor (BDNF) levels during luteal phase in women associated with PMS have more alterations than women not suffering from PMS. In this regard, altered luteal BDNF levels in women with PMS might play a role in a set of psychological and somatic symptoms of the PMS. Studies of last decade revealed neuroprotective effects of curcumin and its ability to increase BDNF levels. In the present study, we evaluated the effect of curcumin on serum BDNF level and PMS symptoms severity in women with PMS. Present study is a Randomized, Double-Blinded, Placebo-Controlled Clinical Trial. Curcumin treatment was given for three successive menstrual cycles and each cycle ran 10 days. After having identified persons with PMS, participants were randomly allocated into placebo (n=35) and curcumin (n=35) groups. Each sample in placebo and curcumin groups received two capsules daily for seven days before menstruation and for three days after menstruation for three successive menstrual cycles. Participants noted the severity of the symptoms mentioned in the daily record questionnaire. Self-report was used to determine menstrual cycle phase of participants. At the fourth day of each menstrual cycle venous blood samples were collected for BDNF measurement by ELISA method. Before intervention, BDNF levels and mean scores of PMS symptoms (mood, behavioral and physical symptoms) between two groups showed no significant differences. But in curcumin group first, second and third cycles after interventions BDNF levels were significantly higher and mean scores of PMS symptoms were significantly less than placebo group. Based on our results part of these beneficial effects of curcumin may be mediated through enhancing serum BDNF levels in women with PMS.

  10. A ring D chromosome in association with Down's syndrome-like phenotype

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    A. Wajntal

    1973-03-01

    Full Text Available The case of a ten-years-old mentally retarded girl with Down's syndrome-like features whose chromosome analysis revealed an unusual mosaicism including 10% mitosis with a ring chromosome replacing a D chromosome is reported. The clinical features of the patient were considered similar to those described by Jacobsen (1966 and Emberger et al. (1971 who interpreted the ring chromosome present in their patients as being chromosome 15.Relata-se um caso de uma menina com 10 anos de idade, mentalmente retardada e com semelhanças com a síndrome de Down, cuja análise cromossômica revelou um mosaicismo pouco freqüente, incluindo 10% de mitoses com um cromossoma em anel substituindo um cromossoma D. O quadro clínico da paciente é similar ao descrito por Jacobsen (1966 e Emberger et al. (1971 que interpretaram a presença do cromossoma em anel em seus pacientes como sendo o cromossoma 15.

  11. SUPLEMENTASI DAUN TORBANGUN (COLEUS AMBOINICUS LOUR UNTUK MENURUNKAN KELUHAN SINDROM PRAMENSTRUASI PADA REMAJA PUTRI (SUPPLEMENTATION OF TORBANGUN LEAVES [COLEUS AMBOINICUS LOUR] IN REDUCING THE COMPLAINST OF PRE-MENSTRUAL SYNDROME [PMS] AMONG TEENAGE G

    Directory of Open Access Journals (Sweden)

    Mazarina Devi

    2013-07-01

    Full Text Available ABSTRACT Background: Torbangun leaves (Coleus ambonicus Lour is one of type of species from Labiatae family which contains a lot of micronutrient and active element which have been examined as beneficial for human health and quality of life. The plants containing iridoid and flavonoid as well as phytochemical which deal with reproduction hormone is applicable to traditional medication toward PMS cases. Methods: The present study was aimed to assess the efficacy of CAL leaves in the management of PMS. An experimental clinical trial was conducted in 35 teenagers with PMS. Three intervention groups were defined: CAL leaves; commercial preparation; and placebo. Participants were followed-up individually for 1 month. Result: The results showed average menarche occurred around age 13 years, with menstruation lasting 5 days. During each successive treatment cycle, participants experienced a lower pain intensity score. Chi Square test, after adjusting each cycle for baseline pain, treatment compliance and other variables, showed that the group receiving CAL extract had significantly reduced pain intensity (p<0.05 compared with commercial preparation and placebo. Conclusion: The torbangun leaves supplement can be used as treatment to relief symptoms of the premenstrual syndrome. [Penel Gizi Makan 2010, 33(2:180-194]   Keywords: Torbangun leaves (Coleus amboinicus Lour, pre-menstrual syndrome (PMS, teenage girls

  12. Premenstrual syndrome and life quality in Turkish health science students.

    Science.gov (United States)

    İşik, Hatice; Ergöl, Şule; Aynioğlu, Öner; Şahbaz, Ahmet; Kuzu, Ayşe; Uzun, Müge

    2016-04-19

    The purpose of the present study was to investigate the incidence of PMS, risk factors affecting PMS symptoms, and life quality in health science students. A total of 608 volunteer female students studying at the health campus of a state university in Turkey were included in the study. The participants were asked to fill out questionnaires on sociodemographic data, PMS symptoms, and SF-36 life quality tests. The overall frequency of PMS among participants was 84.5%. The average PMS and general health SF scores were 118.34 ± 37.3 and 20.03 ± 3.72, respectively. Students who had irregular breakfast, drank ≥2 cups of coffee/day, and consumed alcohol or fast food had higher PMS scores. Irregular menstruation and family history increased PMS scores and decreased life quality (P students significantly decreased as the severity of PMS increased (P consumption and irregular breakfasts, and coffee and alcohol consumption increased PMS risk significantly. In order to improve their life quality, students should be informed about the symptoms, risk factors, and management options of PMS.

  13. RELACIÓN ENTRE RENDIMIENTO LABORAL Y SÍNDROME PREMENSTRUAL

    OpenAIRE

    Espina V.,Natalia; Fuenzalida A.,Alejandra; Urrutia S,María Teresa

    2005-01-01

    El Síndrome Premenstrual (SPM) afecta a gran cantidad de mujeres en edad reproductiva y se caracteriza por una repetición cíclica de síntomas físicos y psicológicos que, en algunos casos, pueden llegar a ser lo suficientemente severos como para interferir en los patrones de vida. El objetivo de esta revisión bibliográfica es conocer cómo afecta el SPM el rendimiento laboral de las mujeres. A pesar de las significativas repercusiones personales y económicas, existen pocas investigaciones que e...

  14. FORMULASI MINUMAN SUPLEMEN DAUN TORBANGUN (Coleus amboinicus Lour. UNTUK WANITA YANG MENDERITA PMS (PREMENSTRUAL SYNDROME

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    Pramadya Alfitra

    2012-03-01

    Full Text Available 800x600 Normal 0 false false false IN X-NONE X-NONE MicrosoftInternetExplorer4 Torbangun (Coleus amboinicus Lour is one of Labiatae family containing a lot of micronutrients and active components. The plant is used as traditional medicine for relieving premenstrual syndromes (PMS. Based on the results of previous studies, a capsule containing 750 mg of dried Torbangun leaves can relieve PMS as well as commercial herbal, and better than placebo. Capsule supplement form seems less acceptable because it tastes like taking a drug. Therefore, it requires development for Torbangun supplement product in other forms, and one of them is a supplement drink. The study is aimed to formulate  a supplement drink from Torbangun leaves as the basic ingredients. Supplement drink formulation is made in trial and error by combining extract of torbangun leaves, sucrose, and lemon, obtaining three formulas: DT1 contains 10 g extract of torbangun leaves and 16 g sucrose, DT2 contains 10 g extract of torbangun leaves, 2 g lemon, 22 g sucrose, and DT3 contains 10 g extract of torbangun leaves, 4 g lemon, and 28 g sucrose. These formulas are then tested by organoleptic, physical, and chemical. The results show that the formula DT3 has the highest average score. Blanching treatment improves organoleptic properties of supplement drinks. Mean scores in color, aroma, and taste of the blanched supplement drink are different (p Key words: Torbangun leaves, premenstrual syndrome, supplement drink, blanching.

  15. 星状神经节阻滞治疗经前期综合征的研究%Study of stellate ganglion block in the treatment of premenstrual syndrome

    Institute of Scientific and Technical Information of China (English)

    王宏伟; 田斌斌; 顾春亮; 胡百奇; 张瑞杰; 贺淑君; 郭玉娜

    2015-01-01

    Objective It is to observe the curative effect of stellate ganglion block therapy on premenstrual syndrome and the effect on serum estradiol ( E2 ) and progesterone ( P) .Methods 112 patients under stellate ganglion block were selected as observation group, which was treated with the injection 7 days after menstruation once time per 3 days, 4 times for 1 courses, 7 days after the next menstruation the treatment continued, and they patients were treated for 3 menstruation cycles.Some healthy women volunteers with the same age as observation group were selected as control group.Blood samples were collected before and after four different periods of menstrual cycle in both groups to detect serum E2 and P content by radioimmunoassay. The changes of major symptoms of premenstrual syndrome ( premenstrual breast swelling pain, insomnia, dysmenorrhea, men-strual headache, irritability, menstrual edema) were observed during the treatment course, and the total curative effect was e-valuated after 3 cycles of treatment.Results 100 cases of patients completed their treatment in observation group.The level of E2 decreased much in secretion and proliferation stage, P secretion peak was lacking;E2 proliferative phase, secretory phase appeared two peak of stellate ganglion block therapy after 3 cycles, and close to the normal level(P<0.01);P secretion peak return to normal.In the treatment of the third menstrual cycles, the total effective rates of the 6 major symptoms of premenstru-al syndrome, premenstrual breast pain, insomnia, menstrual headache, irritability, the edema were all 100%, that of abdomi-nal pain reached 95%.The total efficiency was 96%after 3 cycles of treatment.Conclusion Hormone level changes periodi-cally in different phases of menstrual cycle, especially serum E2 , P changes is the important mechanism in patients with differ-ent symptoms of premenstrual syndrome;stellate ganglion block through a misaligned on E2 , P hormone level changes periodi-cally to

  16. The ESC/E(Z) complex, an effector of response to ovarian steroids, manifests an intrinsic difference in cells from women with premenstrual dysphoric disorder.

    Science.gov (United States)

    Dubey, N; Hoffman, J F; Schuebel, K; Yuan, Q; Martinez, P E; Nieman, L K; Rubinow, D R; Schmidt, P J; Goldman, D

    2017-01-03

    Clinical evidence suggests that mood and behavioral symptoms in premenstrual dysphoric disorder (PMDD), a common, recently recognized, psychiatric condition among women, reflect abnormal responsivity to ovarian steroids. This differential sensitivity could be due to an unrecognized aspect of hormonal signaling or a difference in cellular response. In this study, lymphoblastoid cell line cultures (LCLs) from women with PMDD and asymptomatic controls were compared via whole-transcriptome sequencing (RNA-seq) during untreated (ovarian steroid-free) conditions and following hormone treatment. The women with PMDD manifested ovarian steroid-triggered behavioral sensitivity during a hormone suppression and addback clinical trial, and controls did not, leading us to hypothesize that women with PMDD might differ in their cellular response to ovarian steroids. In untreated LCLs, our results overall suggest a divergence between mRNA (for example, gene transcription) and protein (for example, RNA translation in proteins) for the same genes. Pathway analysis of the LCL transcriptome revealed, among others, over-expression of ESC/E(Z) complex genes (an ovarian steroid-regulated gene silencing complex) in untreated LCLs from women with PMDD, with more than half of these genes over-expressed as compared with the controls, and with significant effects for MTF2, PHF19 and SIRT1 (PMolecular Psychiatry advance online publication, 3 January 2017; doi:10.1038/mp.2016.229.

  17. Shuyu Capsules Relieve Premenstrual Syndrome Depression by Reducing 5-HT3AR and 5-HT3BR Expression in the Rat Brain

    Science.gov (United States)

    Li, Fang; Feng, Jizhen; Gao, Dongmei; Wang, Jieqiong; Song, Chunhong; Wei, Sheng

    2016-01-01

    The effects of the Shuyu capsule on 5-HT3AR and 5-HT3BR expression in a rat model of premenstrual syndrome (PMS) depression and on 5-HT3AR and 5-HT3BR expression and hippocampal neuron 5-HT3 channel current were investigated, to elucidate its mechanism of action against PMS depression. PMS depression model rats were divided into depression and Shuyu- and fluoxetine-treated groups, which were compared to control rats for frontal lobe and hippocampal 5-HT3AR and 5-HT3BR expression and behavior. The depressed model rats displayed symptoms of depression, which were reduced in treated and normal control rats. Frontal lobe and hippocampal 5-HT3AR and 5-HT3BR levels were significantly higher in the model versus the control group and were significantly lower in the Shuyu group. As compared to control rats, the 5-HT3R channel current in the model group was significantly higher; the 5-HT3R channel current in hippocampal neurons treated with serum from Shuyu group rats was significantly lower than that in those treated with model group serum. Thus, PMS depression may be related to 5-HT3AR and 5-HT3BR expression and increased 5-HT3 channel current. Shuyu capsules rectified abnormal 5-HT3AR and 5-HT3BR expression and 5-HT3 channel current changes in a rat model; this finding may provide insight into treating PMS depression.

  18. ASSESSING ONLINE SELF-SUPPORT: ANSWERS FACE THE PREMENSTRUAL DYSPHORIC DISORDER EMERGENCE

    Directory of Open Access Journals (Sweden)

    Agustin Quilez-Clavero

    2015-12-01

    Full Text Available Through the content analyze of two Internet self-support forums, spontaneously organized by women suffering Premenstrual dysphoric disorder, it is wanted The Social Work to attract its attention about the need of taking up professional initiatives generally to online Social Work practice and particularly to online self-support groups. This disorder is barely known. It causes serious consequences for the patients who have to tackle with frequent lack of understanding. This seriousness, often causes, affected are forced to drop out their jobs, or relationships like couples or friendships. Self-support becomes a relief to them who can express themselves on the Internet with people suffering the same situation. It has been a task for Social Work, supporting groups needing a convenient organization for obtaining an optimal empowerment. This challenge about Online Social Work practice is not common; consequently it is an interesting challenge for the Social Work of the beginning of the century.

  19. Premenstrual Exacerbation of Life-Threatening Asthma: Effect of Gonadotrophin Releasing Hormone Analogue Therapy

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    Alun L Edwards

    1996-01-01

    Full Text Available Variability in the severity of asthma during various phases of the menstrual cycle has been frequently suspected. However, the hormonal changes that might affect mediators of bronchospasm have yet to be elucidated. The case of a 41-year-old woman suffering from longstanding asthma with life-threatening exacerbations is reported. The patient was treated with buserelin, a gonadotropin releasing hormone (GnRH analogue, which created a temporary chemical menopause and thus permitted diagnosis of a premenstrual exacerbation of asthma and offered insight into potential therapy. GnRH analogues may therefore be of value in assessing women with severe asthma suspected to vary with the menstrual cycle. The addition of estrogens and progestins at the same time as treatment with GnRH analogue may be of value in determining the role of these hormones in the pathogenesis of menstrually related exacerbations of asthma.

  20. Sexual desire changes during menstrual cycle and relationship with premenstrual syndrome

    Directory of Open Access Journals (Sweden)

    Kiani Asiabar A.

    2007-09-01

    Full Text Available Background: Sexual function in women may be affected by their menstrual cycle. Lack of sexual drive is a deficiency or absence of sexual fantasies and desire for sexual activity. This study aims at determining the changes in sexual desire during the menstrual cycle and those associated with premenstrual syndrome (PMS and evaluates sexual desire during the menstrual cycle and the associated changes with PMS. Methods: The sample for this cross-sectional study includes 150 women employed in factories in Tehran. The instruments for data collection were questionnaires and journals of premenstrual experiences.Results: Analysis of the data showed that the mean age of the subjects was 31 years standard deviation = 8.46(. The most frequent decrease in sexual desire was during the week prior to the start of menstrual bleeding (27.3% and the least frequent was from the end of bleeding to one week before the next period of menstrual bleeding (5.3%. In 24.7% of the cases, an increase in sexual desire occurred during the middle of the menstrual cycle and 27.3% during the course of menstrual bleeding. Moreover, 10.7% of the subjects had an increase in sexual desire during the week before bleeding. Furthermore, a positive correlation was found between changes in sexual desire and PMS (p<0.001. In addition, a positive correlation was found between changes in sexual desire and breast tenderness, joint and muscle pain. Conclusions: The sexual desire of women, with or without PMS, changes during the menstrual cycle. The greatest decrease in sexual desire occurs during the first week before menstrual bleeding in women with PMS. Such information can greatly help toward understanding and treatment in sexual therapy for couples.

  1. Effect of an Educational Intervention Based on Construal Level Theory on Decision Making in Adolescents with Premenstrual Syndrome

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    Fazllollah Ghofranipour

    2014-01-01

    Full Text Available Background: In this study, the existing challenge about the association of construal level and temporal distance was examined. Doing so, the effect of two types of educational intervention on progress of decision making stages in students with premenstrual syndrome (PMS was studied, based on theoretical concepts of construal level. Materials and Methods: The present study is a randomized field trial research conducted on 1578 high school students. A total of 255 students in the second stage of the precaution adoption process model were chosen randomly. They then went through educational intervention based on either low or high construal levels of relaxation method. Results: Subjects in the intervention group showed a higher decision-making stage progression than in control group (p<0.001. The two-stage progression was significantly salient in low construal level-based intervention group (p=0.012. None of the demographic, premenstrual, and premenstrual syndrome severity characteristics were related to this progression. Conclusion: Inducing low construal level causes an individual shift toward desired action more rapidly. That is, there is a correlation between construal level and temporal distance. To accelerate the adoption of any health behavior, temporal distance can be taken as a basic and essential topic.

  2. Premenstrual syndrome

    Science.gov (United States)

    ... Sleep problems (sleeping too much or too little) Exams and Tests There are no specific signs or ... drink soft drinks, alcohol, or other beverages with caffeine. This will help reduce bloating, fluid retention, and ...

  3. The role of perceived control over anxiety in prospective symptom reports across the menstrual cycle.

    Science.gov (United States)

    Mahon, Jennifer N; Rohan, Kelly J; Nillni, Yael I; Zvolensky, Michael J

    2015-04-01

    The present investigation tested the role of psychological vulnerabilities to anxiety in reported menstrual symptom severity. Specifically, the current study tested the incremental validity of perceived control over anxiety-related events in predicting menstrual symptom severity, controlling for the effect of anxiety sensitivity, a documented contributor to menstrual distress. It was expected that women with lower perceived control over anxiety-related events would report greater menstrual symptom severity, particularly in the premenstrual phase. A sample of 49 normally menstruating women, aged 18-47 years, each prospectively tracked their menstrual symptoms for one cycle and completed the Anxiety Control Questionnaire (Rapee, Craske, Brown, & Barlow Behav Ther 27:279-293. doi: 10.1016/S0005-7894(96)80018-9 , 1996) in their follicular and premenstrual phases. A mixed model analysis revealed perceived control over anxiety-related events was a more prominent predictor of menstrual symptom severity than anxiety sensitivity, regardless of the current cycle phase. This finding provides preliminary evidence that perceived control over anxiety-related events is associated with the perceived intensity of menstrual symptoms. This finding highlights the role of psychological vulnerabilities in menstrual distress. Future research should examine whether psychological interventions that target cognitive vulnerabilities to anxiety may help reduce severe menstrual distress.

  4. 女大学生经前期综合征与学校适应性相关性分析%Correlation between premenstrual syndrome and adaptability for female college students

    Institute of Scientific and Technical Information of China (English)

    宋培歌; 王代娣; 吴恺君; 刘兆; 谢红

    2013-01-01

    目的 了解女大学生经前期综合征与学校适应性及两者的相关性,为采取有针对性的入学教育提供建议.方法 便利整群抽取北京大学医学部2011年新入学女大学生445名,采用一般资料调查表、经前期综合征调查表、经前期综合征症状打分表、学校适应水平量表进行调查.结果 新入学女大学生中46.3%有不同程度的经前期综合征,突出表现的症状为易激动、注意力不集中、嗜睡及焦虑;新人学女大学生总体适应性水平得分为(244.97 ±30.89)分,城镇生源在角色适应性和环境的总体认同上优于农村生源(P值均<0.01);除职业选择适应性维度之外,新人学女大学生经前期综合征严重程度与总体学校适应性及其余各维度均呈负相关(P值均<0.01).结论 经前期综合征与学校适应性之间呈负相关,应引起学校的高度重视,通过各种途径改善女大学生的生理心理卫生状况.%Objective To study the prevalence and the relationship of premenstrual syndrome ( PMS) and adaptability in female college students. Methods For convenience, a cluster sampling of the 445 newly enrolled female students from the Health Science Centre of Peking University in 2011 was surveyed for data collection by using of series of questionnaires; The general information questionnaire, the questionnaire of premenstrual syndrome, the level of premenstrual syndrome, and the school adaption questionnaire. Results It was found that 46. 3% of female college students suffered from premenstrual syndrome and the major symptoms were irritability, impaired concentration, drowsiness and anxiety. Further study revealed that the average score of the o-verall adaptability of the newly enrolled female students was (244. 97 ± 30. 89) , and score in self-adaptability and environmental general evaluation for urban students were significantly better than that for rural students ( P <0. 01). Finally, in addition to

  5. PENGARUH RELAKSASI GUIDED IMAGERY PADA GANGGUAN PREMENSTRUAL SYNDROM (PMS REMAJA PUTRI

    Directory of Open Access Journals (Sweden)

    Hanna Sriyanti Saragih

    2017-03-01

    Full Text Available Menstruasi adalah perdarahan secara periodik dan terjadi menurut siklusnya dari rahim. Nyeri menstruasi adalah nyeri saat menstruasi yang terasa di perut bagian bawah dan muncul sebelum, selama atau setelah menstruasi. Relaksasi Guided Imagery secara umum sebagai metode yang paling efektif terutama pada pasien yang mengalami nyeri sehingga perlu dilakukan penelitian pengaruh terapi relaksasi terhadap nyeri. Tujuan penelitian ini adalah untuk menganalisis perbedaan derajat nyeri menstruasi sebelum dan sesudah dilakukan relaksasi Guided Imagery. Penelitian ini merupakan penelitian kuantitatif dengan desain quasi experimental dengan pre and post test control goup design untuk mengetahui pengaruh relaksasi guided imagery terhadap nyeri menstruasi. Data dianalisa menggunakan uji Mann_Whitney, dan nilai p<0.05 dianggap bermakna secara statistik. Setelah dilakukan relaksasi guided imagery didapati hasil rerata nyeri menstruasi pada kelompok perlakuan sebesar 2,6 ± 0,5 dan rerata nyeri menstruasi pada kelompok kontrol sebesar 4,6 ± 0,6. Dari hasil penelitian dapat disimpulkan bahwa relaksasi guided imagery berpengaruh terhadap nyeri menstruasi. Kata kunci: Pre-Menstrual Syndrom, Relaksasi, Guided Imagery

  6. Is catechol-o-methyltransferase gene polymorphism a risk factor in the development of premenstrual syndrome?

    Science.gov (United States)

    Deveci, Esma Ozturk; Selek, Salih; Camuzcuoglu, Aysun; Hilali, Nese Gul; Camuzcuoglu, Hakan; Erdal, Mehmet Emin; Vural, Mehmet

    2014-01-01

    Objective The objective of this study was to investigate whether there was a correlation between catechol-o-methyltransferase (COMT) gene polymorphism, which is believed to play a role in the etiology of psychotic disorders, and premenstrual syndrome (PMS). Methods Fifty-three women with regular menstrual cycles, aged between 18 and 46 years and diagnosed with PMS according to the American Congress of Obstetrics and Gynecology criteria were included in this study as the study group, and 53 healthy women having no health problems were selected as the controls. Venous blood was collected from all patients included in the study and kept at -18℃ prior to analysis. Results There was no significant difference between the groups in terms of demographic features such as age, body mass index, number of pregnancies, parity, and number of children. No statistically significant difference was observed in terms of COMT gene polymorphism (p=0.61) between women in the PMS and the control groups. However, a significant difference was found between arthralgia, which is an indicator of PMS, and low-enzyme activity COMT gene (Met/Met) polymorphism (p=0.04). Conclusion These results suggested that there was no significant relationship between PMS and COMT gene polymorphism. Since we could not find a direct correlation between the COMT gene polymorphism and PMS, further studies including alternative neurotransmitter pathways are needed to find an effective treatment for this disease. PMID:25045629

  7. Germline mutation of CBL is associated with moyamoya disease in a child with juvenile myelomonocytic leukemia and Noonan syndrome-like disorder.

    Science.gov (United States)

    Hyakuna, Nobuyuki; Muramatsu, Hideki; Higa, Takeshi; Chinen, Yasutsugu; Wang, Xinan; Kojima, Seiji

    2015-03-01

    Germline mutations in CBL have been identified in patients with Noonan syndrome-like phenotypes, while juvenile myelomonocytic leukemia (JMML) harbors duplication of a germline CBL, resulting in acquired isodisomy. The association between moyamoya disease and Noonan syndrome carrying a PTPN11 mutation has recently been reported. We present a patient with JMML who developed moyamoya disease and neovascular glaucoma. Our patient exhibited a Noonan syndrome-like phenotype. Genetic analysis revealed acquired isodisomy and a germline heterozygous mutation in CBL. This is a rare case of CBL mutation associated with moyamoya disease. Prolonged RAS pathway signaling may cause disruption of cerebrovascular development.

  8. Menstrual-related attitudes and symptoms among multi-racial Asian adolescent females.

    Science.gov (United States)

    Wong, Li Ping; Khoo, Ee Ming

    2011-09-01

    Menstruation has important implications on the physical and emotional well-being of adolescents' reproductive health. This study aimed to investigate the perception towards menstruation and premenstrual syndrome (PMS), to provide insight into menstrual-related education information in order to help adolescent girls manage the physical and psychological changes associated with menstruation. This cross-sectional study included 1,092 adolescent females from 94 schools in the Federal Territory of Kuala Lumpur, Malaysia. A self-administered semi-structured questionnaire was used in the data collection. The results showed the mean scores on the menstrual attitude questionnaire to be 2.80 (SD ±1.88) out of six. A total of 80.7% and 83.6% of the participants experienced one or more affective and somatic symptoms respectively in the premenstrual phase. Irritability, mood swing and tension were the three most frequently reported affective symptoms, while fatigue and menstrual cramps were highly prevalent somatic symptoms in both the premenstrual and menstrual phases. The effects on functional impairment and quality of life, in order of importance, include poor class concentration, restriction of social and recreational activities, difficulty to mingle with friends, and poor class performance. Despite the evident impact, only 10.3% of adolescent girls consulted doctors for PMS symptoms, while one-third did nothing about their condition. There were ethnic differences in the seeking of treatment for PMS. The study calls for an education program related to PMS and menstrual-related disorders to provide information and support to adolescents. This will help them to cope better with menstrual-related problems, and encourage positive attitudes to menstruation.

  9. Mastalgia cíclica pré-menstrual: placebo versus outras drogas Pre-menstrual cyclic mastalgia

    Directory of Open Access Journals (Sweden)

    Laurival A. De Luca

    2006-08-01

    compound of retinol, pyridoxine chlorhydrate and tocopherol acetate. METHODS: The study is a prospective, controlled, triple blinded, randomized trial. From 259 patients, 81 were selected in order to follow rigid criteria of inclusion. They were divided into three groups of 27 patients, taking aspirin, vitamins or placebo respectively. The number of patients in each group was considered satisfactory for statistical analysis. Pain was scored as Grade 1 (without pain, Grade II (moderate pain and Grade III (severe pain. The Tukey test was applied for comparison of results (statistical significance 5%. RESULTS: Clinical parameters, age, weight, BMI, parity and lactation period were similar for each group. There was a decrease of pain intensity in all groups, that was even more pronounced for the placebo group. DISCUSSION: Emphasis was given to symptomatic treatment of cyclic premenstrual mastalgia with symptoms considered to be the expression of a physiological process that can be treated with simple drugs or placebo. Usual therapeutic approaches with several drugs are criticized, including results and contraindications. CONCLUSION: This study based upon acceptable trial methodology (randomized, triple blinded, placebo controlled, prospective did not show significant differences in the treatment of cyclic mastalgia.

  10. Essential fatty acids for premenstrual syndrome and their effect on prolactin and total cholesterol levels: a randomized, double blind, placebo-controlled study

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    Pinho Neto João S

    2011-01-01

    Full Text Available Abstract Objective To evaluate the effectiveness and safety of polyunsaturated fatty acids for the treatment of the premenstrual syndrome (PMS using a graded symptom scale and to assess the effect of this treatment on basal plasma levels of prolactin and total cholesterol. Methods A randomized, double-blind, placebo-controlled study was conducted with 120 women with PMS divided into three groups and treated with 1 or 2 grams of the medication or placebo. Symptoms were recorded over a 6-month period using the Prospective Record of the Impact and Severity of Menstruation (PRISM calendar. Total cholesterol and prolactin levels were measured. Analysis of variance (ANOVA, Pearson's chi-square test, Wilcoxon's nonparametric signed-rank test for paired samples and the Mann-Whitney nonparametric test for independent samples were used in the statistical analysis. Results There were no differences in age, marital status, schooling or ethnicity between the groups. In the group treated with 1 gram of the medication, a significant reduction was found when the median PRISM score recorded in the luteal phase at baseline (99 was compared with the median score recorded in the 3rd month (58 and in the 6th month of evaluation (35. In the 2-gram group, these differences were even more significant (baseline score: 98; 3rd month: 48; 6th month: 28. In the placebo group, there was a significant reduction at the 3rd but not at the 6th month (baseline: 96.5; 3rd month: 63.5; 6th month: 62. The difference between the phases of the menstrual cycle was greater in the 2-gram group compared to the group treated with 1 gram of the medication. There were no statistically significant differences in prolactin or total cholesterol levels between baseline values and those recorded after six months of treatment. Conclusion The difference between the groups using the medication and the placebo group with respect to the improvement in symptomatology appears to indicate the

  11. The Effects of Sertraline in Controlling Refractory Hypertension in Women with Premenstrual Syndrome

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    Fatemeh Ranjbar

    2016-12-01

    Full Text Available Objective: The aim of this study was to evaluate the effect of Premenstrual Syndrome (PMS treatment with selective serotonin reuptake inhibitor (SSRI on treatment response of refractory hypertension of the patients.Method: This was a triple-blind randomized clinical trial conducted on female patients suffering from refractory hypertension and PMS at the same time. We obtained informed consent from 40 patients who had inclusion criteria and selected 20 patients for the intervention (sertraline 50 mg daily and 20 for the control groups. The study period was five weeks. The mean of systolic and diastolic blood pressure before and after intervention was measured separately for each individual in each group and the mean of blood pressure of the members of the two groups were compared with each other.Results: The mean age of the participants was 43.60 ± 4.57. In this study, systolic and diastolic blood pressure of both groups reduced after intervention. The mean of systolic blood pressure was reduced by 40.86 mmHg in the intervention group and this reduction was 16 mm Hg in control group after intervention (P<0.001. Comparing this reduction between the two groups, we found that reduction rate in systolic blood pressure of the two groups did not have a significant statistical difference before and after the intervention (P = 0.11. Mean of diastolic blood pressure also showed reduction of 9.17 mm Hg and that of control group showed 6.7-mmHg reduction. Reduction rate of diastolic blood pressure in the intervention group had a statistically significant difference with that of the control group (P<0.017.‎‎Conclusion: Administration of sertraline is more effective in controlling diastolic blood pressure in women suffering from refractory hypertension and comorbid PMS.

  12. Treatment of premenstrual tension syndrome with Vitex agnus castus controlled, double-blind study versus pyridoxine.

    Science.gov (United States)

    Lauritzen, C; Reuter, H D; Repges, R; Böhnert, K J; Schmidt, U

    1997-09-01

    The objective of the present study was to determine the efficacy and tolerability of a new solid formulation (capsules) of Agnolyt®(*)) in a randomized, controlled trial versus pyridoxine in women with PMTS over a period of three treatment cycles (Vitex agnus castus (VAC): 1 capsule + 1 placebo capsule/day, n = 90; pyridoxine (B6): 2 capsules day, n = 85). The therapeutic response was assessed using the premenstrual tension syndrome scale (PMTS scale), the recording of six characteristic complaints of the syndrome, and the clinical global impression scale (CGI scale). Upon completion of the trial, efficacy of the treatment was assessed by the physician as well as by the patient. On the PMTS scale, treatment with VAC and B6 produced a reduction in score points from 15.2 to 5.1 (-47,4%) and from 11.9 to 5.1 (-48%)(*), respectively. In comparison with pyridoxine, VAC caused a considerably more marked alleviation of typical PMTS complaints, such as breast tenderness, edema, inner tension, headache, constipation, and depression. Analogous results were obtained with the CGI scale. In both treatment groups, efficacy was rated as at least adequate by more than 80% of the investigators; however, VAC treatment was rated as excellent by 24.5% and pyridoxine treatment by 12.1% of the investigators. According to the patients' assessment, 36.1% of the cases in the VAC group and 21.3% in the pyridoxine group were free from complaints. Adverse events (gastrointestinal and lower abdominal complaints, skin manifestations and transitory headache) occurred in 5 patients under B6 and in 12 patients under VAC. Serious adverse events were not observed. The results of the present study confirm the efficacy and safety of Agnolyt® capsules in the treatment of PMTS.

  13. Premenstrual syndrome and dysmenorrhea: urban-rural and multiethnic differences in perception, impacts, and treatment seeking.

    Science.gov (United States)

    Wong, Li Ping

    2011-10-01

    Attitudes toward menarche and menstruation are largely influenced by sociological, cultural, and family environmental factors. Recognizing the influential effects that these factors might have on shaping adolescents' attitudes is crucial in designing a more effective means of transmitting health information. This study aimed to gather an in-depth understanding of perceptions, impacts, and treatment seeking on menstruation-related issues from an ethnically mixed group of rural and urban girls. In total, 27 focus group discussions (172 participants) were conducted between November 2008 and April 2009. Participants were adolescent girls aged 13-19 years, recruited from 7 public secondary schools in the Federal Territory of Kuala Lumpur and 4 public secondary schools from the rural districts of Kelantan, in Malaysia. Many participants revealed that they were not given or had not received detailed information about the mechanism or physiology of menstruation prior to its onset. Thus, many described the onset of menarche as shocking, an event for which they were unprepared, and which has had a tremendous impact on their emotions. More positive acceptance of menarche was reported in the urban than with the rural groups. Despite the high prevalence of premenstrual syndrome and dysmenorrhea, participants across urban-rural and ethnic groups perceived the problems as completely normal, hence they relied on self-care methods and did not want to seek professional treatment. More rural girls compared to urban girls were embarrassed to talk to their mothers or consult their physicians regarding menstruation-related problems. Menstruation-related education would have a positive impact in improving adolescent girls' knowledge and in nurturing a positive attitude toward menstruation-related matters at home, at school, and in the community. Copyright © 2011 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

  14. Mental and Reproductive Health Correlates of Academic Performance among Debre Berhan University Female Students, Ethiopia : The Case of Premenstrual Dysphoric Disorder

    NARCIS (Netherlands)

    Alemu, Sisay Mulugeta; Habtewold, Tesfa Dejenie; Haile, Yohannes Gebreegziabhere

    2017-01-01

    Background. Globally 3 to 8% of reproductive age women are suffering from premenstrual dysphoric disorder (PMDD). Several mental and reproductive health-related factors cause low academic achievement during university education. However, limited data exist in Ethiopia. The aim of the study was to

  15. Exposure to phthalates among premenstrual girls from rural and urban Gharbiah, Egypt: A pilot exposure assessment study

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    Hablas Ahmed

    2011-05-01

    Full Text Available Abstract Background Phthalates have been identified as endocrine active compounds associated with developmental and reproductive toxicity. The exposure to phthalates in premenstrual Egyptian females remains unknown. The objective of this study was to characterize phthalate exposure of a potentially vulnerable population of premenstrual girls from urban and rural Egypt. Materials and methods We collected one spot urine sample from 60 10-13 year old females, 30 from rural Egypt, and 30 from urban Egypt from July to October 2009. Samples were analyzed for 11 phthalate metabolites. Additionally, we collected anthropometrics as well as questionnaire data concerning food storage behaviors, cooking practices, and cosmetic use. Phthalate metabolite concentrations were compared between urban and rural Egyptians as well as to age and gender matched Americans. Results Monoethyl phthalate (MEP, was detected at the highest concentration in urine of Egyptian girls (median: 43.2 ng/mL in rural, 98.8 ng/mL in urban. Concentrations of urinary metabolites of di-(2-ethylhexyl phthalate and dibutyl phthalate were comparable between Egyptians and age matched US girls. Storage of food in plastic containers was a statistically significant predictor of urinary mono-isobutyl phthalate (MiBP concentrations when comparing covariate adjusted means. Conclusions Urinary concentrations of phthalate metabolites were similar in Egyptian and US populations, suggesting that phthalate exposure also occurs in developing nations. Dietary intake is likely an important route of exposure to phthalates in both urban and rural populations.

  16. An open-label pilot study to assess the effectiveness of krill oil with added vitamins and phytonutrients in the relief of symptoms of PMS

    Directory of Open Access Journals (Sweden)

    Wakeman MP

    2013-09-01

    Full Text Available Michael P Wakeman School of Cancer Sciences, University of Birmingham, Edgbaston, Birmingham, West Midlands, UK Abstract: An open-label pilot study over 4 months to evaluate the effectiveness of a compound formulation of ingredients, which individually have been demonstrated to be implicated in the pathogenesis of premenstrual syndrome to ameliorate the most troublesome symptoms of the condition. The supplement provided thiamine, riboflavin, pyridoxine, vitamin D, soy isoflavones, rosemary extract, and krill oil and was taken each day for the 3 months of the trial. Statistically significant effect was reported by the 29 women who completed the study in relief of anxiety, bloating, mood swings, breast tenderness, skin outbreaks, food cravings, fatigue, forgetfulness, insomnia, and headache after 3 months of treatment compared with baseline. This pilot study indicates the formulation to be effective, and a larger placebo-controlled trial is now planned. Keywords: thiamine, riboflavin, pyridoxine, vitamin D, soy isoflavones, rosemary extract, premenstrual syndrome

  17. Abdominal bloating and irritable bowel syndrome like symptoms following microinstillation inhalation exposure to chemical warfare nerve agent VX in guinea pigs.

    Science.gov (United States)

    Katos, Alexandre M; Conti, Michele L; Moran, Theodore S; Gordon, Richard K; Doctor, Bhupendra P; Sciuto, Alfred M; Nambiar, Madhusoodana P

    2007-05-01

    While assessing the methylphosphonothioic acid S-(2-(bis(1-methylethyl)amino)ethyl)O-ethyl ester (VX) induced respiratory toxicity and evaluating therapeutics against lung injury, we observed that the animals were experiencing abnormal swelling in the abdominal area. Nerve agent has been known to increase salivary, nasal and gastrointestinal secretion and cause diarrhea. This study was initiated to investigate the effect of VX on the gastrointestinal tract (GI) since abdominal pathology may affect breathing and contribute to the on going respiratory toxicity. The mid-abdominal diameter and the size of the lower left abdomen was measured before and after 27.3 mg/m3 VX exposure by microinstillation and at 30 min intervals up to 2 h post-VX exposure. Both VX and saline exposed animals exhibited a decrease in circumference of the upper abdomen, although the decrease was slightly higher in VX-exposed animals up to 1 h. The waist diameter increased slightly in VX-exposed animals from 60 to 90 min post-VX exposure but was similar to saline controls. The lower left abdomen near to the cecum, 6 cm below and 2cm to the right of the end of the sternum, showed an increase in size at 30-60 min that was significantly increased at 90-120 min post-VX exposure. In addition, VX-exposed animals showed loose fecal matter compared to controls. Necropsy at 24h showed an increased small intestine twisting motility in VX-exposed animals. Body tissue AChE assay showed high inhibition in the esophagus and intestine in VX-exposed animals indicating that a significant amount of the agent is localized to the GI following microinstillation exposure. These results suggest that microinstillatipn inhalation VX exposure induces gastrointestinal disturbances similar to that of irritable bowel syndrome and bloating.

  18. Frequency, determinants, and clinical relevance of acute coronary syndrome-like electrocardiographic findings in patients with acute aortic syndrome.

    Science.gov (United States)

    Biagini, Elena; Lofiego, Carla; Ferlito, Marinella; Fattori, Rossella; Rocchi, Guido; Graziosi, Maddalena; Lovato, Luigi; di Diodoro, Lara; Cooke, Robin M T; Petracci, Elisabetta; Bacchi-Reggiani, Letizia; Zannoli, Romano; Branzi, Angelo; Rapezzi, Claudio

    2007-09-15

    We investigated frequency/characteristics of acute coronary syndrome-like (ACS-like) electrocardiographic (ECG) profiles among patients with a final diagnosis of acute aortic syndrome (AAS), and explored pathophysiologic determinants and prognostic relevance within each Stanford subtype. We blindly reviewed presentation electrocardiograms of 233 consecutive patients with final diagnosis of AAS (164 Stanford type A) at a regional treatment center. Prevalence of ACS-like ECG findings was 27% (type A, 26%, type B, 29%); most were non-ST-elevation myocardial infarction-like. Patients with ACS-like ECG findings more often had coronary ostia involvement (p=0.002), pleural effusion (p=0.02), significant aortic regurgitation (p=0.01), and troponin positivity (p=0.001). ACS-like ECG profile in type A disease was independently associated with coronary ostia involvement (odds ratio [OR] 5.27, 95% confidence interval [CI] 1.75 to 15.88). ACS-like ECG profile predicted in-hospital mortality (OR 2.90, 95% CI 1.24 to 6.12), as did age (each incremental 10-year: OR 1.59, 95% CI 1.14 to 2.22), and syncope at presentation (OR 2.90, 95% CI 1.16 to 7.24). In conclusion, about 25% of our AAS patients (in either Stanford subtype) presented ACS-like ECG patterns-often with non-ST-elevation myocardial infarction characteristics-which could cause misdiagnosis. ACS-like ECG profile was associated with more complicated disease, and in type A disease was a strong independent predictor of in-hospital mortality.

  19. Neuroleptic malignant syndrome-like reaction precipitated by antipsychotics in a patient with gamma-butyrolactone withdrawal.

    Science.gov (United States)

    Eiden, Céline; Capdevielle, Delphine; Deddouche, Charlotte; Boulenger, Jean-Philippe; Blayac, Jean-Pierre; Peyrière, Hélène

    2011-12-01

    We report the case of a patient with chronic abuse of gamma-butyrolactone (GBL, 3 bottles per week for 4 months), who in the course of the management of acute agitation and hallucinations developed symptoms compatible with both neuroleptic malignant syndrome and GBL withdrawal symptoms.Some GHB withdrawal symptoms are similar to those of neuroleptic malignant syndrome, and the administration of antipsychotics might worsen the neurological condition of patients. So, it seems important to rapidly detect drugs taken by patients with mental agitation, to optimize management and minimize complications related to drugs.

  20. Recognizing Symptoms

    Science.gov (United States)

    ... bowel habits. Learn More About Pain in IBS Symptoms Won’t Stop Everyone suffers from bowel changes ... They can be constant or keep coming back. Symptoms Change Some or all of IBS symptoms can ...

  1. Familial Mediterranean fever with P369S/R408Q exon3 variant in pyrin presenting as symptoms of PFAPA.

    Science.gov (United States)

    Yamagami, Keiko; Nakamura, Tomoyuki; Nakamura, Ryota; Hanioka, Yusuke; Seki, Kaori; Chiba, Hiroshi; Kobayashi, Keiko; Agematsu, Kazunaga

    2017-03-01

    Familial Mediterranean fever (FMF) can be classified into typical and incomplete/atypical types. Periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis (PFAPA) syndrome-like symptoms have been found in atypical type carrying P369S-R408Q mutations in the responsible gene MEFV. A 28-year-old female with recurrent fever and her young sisters and mother, all of whom had tonsillectomy for tonsillitis, carried heterozygous alterations involving E148Q/P369S/R408Q. A diagnosis of atypical FMF, MEFV exon3 variants with PFAPA syndrome-like symptoms, was made.

  2. Menopausal symptoms

    OpenAIRE

    Rymer, Janice; Morris, Edward P.

    2011-01-01

    In the UK, the median age for onset of menopausal symptoms is 45.5 to 47.5 years. Symptoms associated with the menopause include vasomotor symptoms, sleeplessness, mood changes, reduced energy levels, loss of libido, vaginal dryness, and urinary symptoms.Many symptoms, such as hot flushes, are temporary, but those resulting from reduced hormone levels, such as genital atrophy, may be permanent.

  3. The G-Protein β3 subunit 825 TT genotype is associated with epigastric pain syndrome-like dyspepsia

    Directory of Open Access Journals (Sweden)

    Hori Kazutoshi

    2010-01-01

    Full Text Available Abstract Background Although familial clustering of functional dyspepsia (FD has been reported, the role of genetics in the susceptibility to FD is still not well understood. Several reports indicate an association between FD and G-protein β3 (GNB3 subunit gene polymorphism (C825T; however, these studies had small sample sizes and the findings are inconclusive. In the present study we clarified the association between GNB3 gene polymorphism and dyspepsia in a large population of Japanese subjects who visited a hospital for annual health check-up. Methods Subjects with significant upper gastrointestinal findings were excluded. Subjects with dyspeptic symptoms were divided into either a postprandial distress syndrome (PDS group or an epigastric pain syndrome (EPS group according to the Rome III criteria. The presence of the GNB3 C825T polymorphism was then evaluated and logistic regression analysis was used to test all variables. Results The GNB3 genotype distribution in subjects without dyspepsia was 191 CC (25.1%, 368 TC (48.4%, and 202 TT (26.5% and 17 CC (25.0%, 29 TC (42.6%, and 22 TT (32.4% in subjects with dyspepsia. No significant correlation was found between the GNB3 825TT genotype and dyspepsia. However, the TT genotype was significantly associated with subjects with EPS-like symptoms (odds ratio (OR = 2.00, 95% confidence interval (CI; 1.07-3.76 compared to the CT/CC genotype adjusted for gender and age. No significant correlation was found between GNB3 polymorphism and PDS-like symptoms (OR = 0.68, 95% CI; 0.31-1.51. With the exclusion of subjects with both EPS- and PDS-like symptoms, only the TT genotype was significantly associated with EPS-like symptoms (OR = 2.73, 95% CI; 1.23-5.91. Conclusion The homozygous GNB3 825T allele influences the susceptibility to EPS-like dyspepsia.

  4. The Effect of Three Months Regular Aerobic Exercise on Premenstrual Syndrome

    Directory of Open Access Journals (Sweden)

    Zinat Ghanbari

    2008-12-01

    Full Text Available Objective: To determine the effects of three-month regular aerobic exercise on the PMS symptoms. Also correlations with age, education, marital status and severity of PMS symptoms were studied.Materials and Methods: A Quasi- Experimental study was conducted on 91 volunteer women with regular menstrual cycle and no history of gynecological, endocrinological and psychological disorders. The study was done during March 2005- March 2007, in Tehran University of Medical Sciences. A Modified Menstrual Distress Questionnaire (MMDQ was used in this study. Participants were divided into two groups: Non-exercised, they also didn't have any past experience of regular exercise (n= 48 and Exercised (n= 43. The exercise time duration was one hour and was carried out three times per week for three months.  Emotional, behavioral, electrolyte, autonomic, neurovegatative and skin symptoms of PMS were compared between two groups. P value was considered significant at < 0.05.Results: A significant difference was observed for electrolytic, neurovegetative and cognitive symptoms before and after the exercise. Also the severity of skin and neurovegetative symptoms were different in experimental groups with and without past history of doing regular exercise. There was no correlation between age, education, marital status and severity of PMS symptoms.Conclusion: Three months of regular aerobic exercise effectively reduces the severity of PMS symptoms.

  5. Anthrax: Symptoms

    Science.gov (United States)

    ... EID Journal Articles Anthrax-Related MMWRs Medscape Commentaries Symptoms Language: English Español (Spanish) Recommend on Facebook Tweet ... cause severe illness and even death. Cutaneous anthrax symptoms can include: A group of small blisters or ...

  6. An exploratory pilot of factors associated with premenstrual syndrome in minority women

    Directory of Open Access Journals (Sweden)

    Mallory Perry

    2015-06-01

    Conclusions: This pilot evidence of improved PMS symptoms in minority and non-minority groups related to fish oil supplementation supports a universal treatment approach and highlights need for a larger-scale investigation.

  7. Somatic Symptoms

    DEFF Research Database (Denmark)

    Eliasen, Marie; Kreiner, Svend; Ebstrup, Jeanette F

    2016-01-01

    ) the associations between the symptoms, and 3) the associations between the somatic symptoms, self-perceived health and limitations due to physical health accounting for the co-occurrence of symptoms. Information on 19 somatic symptoms, self-perceived health and limitations due to physical health was achieved from...... a population-based questionnaire survey of 36,163 randomly selected adults in the Capital Region of Denmark in 2006/07. Chain graph models were used to transparently identify and describe the associations between symptoms, self-perceived health and limitations due to physical health. In total, 94...... all strongly directly associated with both of the outcomes (γ>0.30). Chest pain was strongly associated with self-perceived health, and other musculoskeletal symptoms and urinary retention were strongly associated with limitations due to physical health. Other symptoms were either moderate...

  8. Adiponectin Potentially Contributes to the Antidepressive Effects of Baduanjin Qigong Exercise in Women With Chronic Fatigue Syndrome-Like Illness.

    Science.gov (United States)

    Chan, Jessie S M; Li, Ang; Ng, Siu-Man; Ho, Rainbow T H; Xu, Aimin; Yao, Tzy-Jyun; Wang, Xiao-Min; So, Kwok-Fai; Chan, Cecilia L W

    2017-03-13

    Our recent study demonstrates that adiponectin signaling plays a significant role in mediating physical exercise-exerted effects on hippocampal neurogenesis and antidepression in mice. Whether the findings can be translated to humans remains unknown. This study aimed to investigate the effects of Baduanjin Qigong exercise on adiponectin and to evaluate whether adiponectin is involved in the antidepressive effects of Qigong exercise on chronic fatigue syndrome (CFS)-like illness. This is a randomized, waitlist-controlled trial. One hundred eight female participants were randomly assigned to either Qigong exercise or waitlist groups. Sixteen 1.5-h Qigong lessons were conducted. Outcome measures were taken at three time points. Baseline adiponectin levels were negatively associated with body weight, body mass index, waist circumference, hip circumference, and waist/hip ratio in women with CFS-like illness. Compared with the waitlist control, Qigong exercise significantly reduced anxiety and depression symptoms and significantly raised plasma adiponectin levels (median = 0.8 vs. -0.1, p Qigong exercise were associated with decreases in depression scores for the Qigong group (r = -0.38, p = 0.04). Moreover, adjusted linear regression analysis further identified Qigong exercise and change in adiponectin levels as the significant factors accounting for reduction of depression symptoms. Baduanjin Qigong significantly increased adiponectin levels in females with CFS-like illness. Decreases in depression symptoms were associated with increases in adiponectin levels following Qigong exercise, indicating that the potential contribution of adiponectin to Qigong exercise elicited antidepressive effects in human subjects.

  9. Compartment syndrome like picture in metaphyseal comminuted fracture of tibia treated by locking plate due to tight closure

    Directory of Open Access Journals (Sweden)

    Prafulla Herode

    2013-01-01

    Full Text Available A 22-year-old male came to casualty on 5 th May 2012 after a fall from motorcycle. He complained of excruciating pain and swelling over right knee. There was an open wound of 7 × 2 cm over supra-patellar region and diffuse swelling over knee joint with severe tenderness over proximal aspect of right tibia. X-ray showed intra-articular fracture of proximal tibia extending to diaphysis classified as type 6 by Schatzker classification for proximal tibia, with fibula shaft transverse fracture. The skin over the fracture was contused. Debridement with primary wound closure was done in emergency. Skeletal traction was applied through a lower tibial Steinman pin. Patient was operated after 15 days when wound healed and swelling subsided. Locking plate was applied on medial aspect using Minimally invasive percutaneous plate osteosysthesis (MIPPO technique. Post-operatively over 4 hours patient developed severe pain and swelling in operated leg which mimicked compartment syndrome. Suture removal was done immediately in the ward from the distal aspect, which relieved the symptoms but lead to exposure of the plate. A rotational flap was done to cover the plate in coordination with a plastic surgeon on the next day.

  10. Diphtheria Symptoms

    Science.gov (United States)

    ... Search Form Controls Cancel Submit Search The CDC Diphtheria Note: Javascript is disabled or is not supported ... message, please visit this page: About CDC.gov . Diphtheria Home About Diphtheria Causes and Transmission Symptoms Complications ...

  11. Plague Symptoms

    Science.gov (United States)

    ... Search Form Controls Cancel Submit Search the CDC Plague Note: Javascript is disabled or is not supported ... message, please visit this page: About CDC.gov . Plague Home Ecology & Transmission Symptoms Diagnosis & Treatment Maps & Statistics ...

  12. The link between neurosteroids and syndromic/syndromal components of the mood spectrum disorders in women during the premenstrual phase

    Directory of Open Access Journals (Sweden)

    Dell'Osso Liliana

    2008-02-01

    Full Text Available Abstract Objectives Females with a lifetime diagnosis of major mood disorder (Bipolar Disorder BD, Major Depressive Disorder MMD investigated during the luteal phase of their menstrual cycle and in a condition of clinical well-being showed higher blood serum concentrations of progesterone and allopregnanolone compared to healthy controls. Women with BD presented even higher levels than those affected by MDD. This study attempted to verify, in line with a dimensional approach, if the possible differences in neurohormonal levels may be directly linked to some syndromal clusters (dimensions of the mood spectrum disorders indipendently of diagnosis. Methods Premenstrual concentrations of allopregnanolone, THDOC, progesterone, and cortisol were measured in 3 groups of women: 17 BD and 14 MDD outpatients, and 16 control subjects. Psychiatric evaluation was performed with the SCID-I interview and the SCI-MOODS-SR questionnaire. The correlation between steroid levels and mood disorder syndromal cluster (SCI-MOODS-SR domains and sub-domains was evaluated by means of analysis of main components with Varimax rotation and Kaiser's normalization (which provided for inclusion of all components with an Eigen value >1. Results Analysis of the main components evidenced the presence of 3 components: 1 mania, 2 depression both with mixed component 3 steroid + manic cognitivity and suicidal ideas. Conclusion Levels of allopregnanolone and progesterone do not correlate with the association of the depressive and manic syndromes, but rather with mixed symptomatological aspects, and in particular with cognitive manic and depressive (with suicidal thoughts dimensions. Further studies should be carried out to confirm these findings.

  13. in Ibadan, Nigeria

    African Journals Online (AJOL)

    experienced during menstruation, attitude towards and management of ... participants experienced symptoms during premenstrual periods than menstrual periods. .... magnesium trisilicate mixture, 10% hyosine Premenstrual syndrome Survey ...

  14. Study Protocol for a Randomized Double Blind, Treatment Control Trial Comparing the Efficacy of a Micronutrient Formula to a Single Vitamin Supplement in the Treatment of Premenstrual Syndrome

    Directory of Open Access Journals (Sweden)

    Hannah Retallick-Brown

    2016-12-01

    Full Text Available Background: The recent addition of Premenstrual Dysphoric Disorder (PMDD to the Diagnostic and Statistical Manual (5th ed. has highlighted the seriousness of this disorder. Many alternatives to psychoactive medication in the form of vitamins, minerals, and plant extracts have been trialled by women seeking a natural treatment approach. We plan to explore whether a well validated micronutrient formula, EMPowerplus Advanced, can outperform a recognized single nutrient treatment, vitamin B6, for the treatment of Premenstrual Syndrome (PMS. Methods: This will be a randomized treatment control study. Eighty women will be recruited and assigned to one of two treatment groups; EMPowerplus Advanced or vitamin B6. Baseline daily data will be collected for an initial two cycles, followed by three months of active treatment. A natural follow up will take place three cycles post treatment. Results: The primary outcome measure will be PMS change scores as based on results from the Daily Record of Severity of Problems (DRSP. The number of treatment responders for each of the two groups will yield a comparison score between the two treatments, with participants deemed as a responder if they show a total PMS score improvement of 50% from their baseline scores on the DRSP. Conclusion: If a micronutrient formula proves more effective for treating PMS, not only does it give women suffering from the condition a viable treatment option, but it may also suggest one cause of PMS; that is insufficient minerals and vitamins.

  15. Characterization of headaches in the premenstrual tension syndrome Caracterização das cefaléias na síndrome da tensão pré-menstrual

    Directory of Open Access Journals (Sweden)

    Yara Dadalti Fragoso

    2009-03-01

    Full Text Available OBJECTIVE: Characterization of headaches in premenstrual syndrome (PMS. Although headache is one of the symptoms for PMS, no details on this headache are given by the American College of Obstetrics and Gynecology (ACOG criteria. METHOD: A group of 45 fertile age women presenting PMS were invited to complete a registration diary for headache and PMS symptoms for three consecutive months. The diary included details of each headache attack, allowing for classification according to the International Headache Society criteria (IHS-2004. RESULTS: Migraine without aura was the most common type of headache in PMS (n=27, 60%, followed by tension type headache (n=15, 30%. Only in two cases the type of headache varied among the observed months, and only in one case the diagnosis could not be concluded by the IHS-2004 criteria. CONCLUSION: Better clinical and therapeutic approach to headache in PMS can be achieved if the patient's type of headache could be properly characterized.OBJETIVO: Caracterização das cefaléias na síndrome da tensão pré-menstrual (TPM. Embora cefaléia seja um dos sintomas associados à TPM, não são fornecidos detalhes sobre esta dor pelos critérios do American College of Obstetrics and Gynecology (ACOG. MÉTODO: Um grupo de 45 mulheres em idade fértil apresentando TPM foi convidado a preencher um diário de registro de cefaléia e dos sintomas de TPM por três meses consecutivos. O diário incluía detalhes de cada crise de cefaléia, permitindo classificação de acordo com os critérios da International Headache Society (IHS-2004. RESULTADOS: Enxaqueca sem aura foi a forma mais freqüente de cefaléia na TPM (n=27, 60%, seguida de cefaléia tipo tensional (n=15, 30%. Em apenas dois casos a cefaléia variou entre os meses observados e em apenas um caso o diagnóstico não pôde ser conclusivo pelos critérios da IHS-2004. CONCLUSÃO: Melhor manejo clínico e terapêutico pode ser obtido na cefaléia da TPM se o tipo de

  16. A dual role for interferon-gamma in the pathogenesis of Sjogren's syndrome-like autoimmune exocrinopathy in the nonobese diabetic mouse.

    Science.gov (United States)

    Cha, S; Brayer, J; Gao, J; Brown, V; Killedar, S; Yasunari, U; Peck, A B

    2004-12-01

    Sjogren's syndrome-like autoimmune exocrinopathy (AEC) in the nonobese diabetic (NOD) mouse progresses from a preimmune phase to an immune phase, resulting in dry mouth and/or dry eyes. In the present study, the impact of the prototypical T-helper type 1 cytokine, interferon-gamma (IFN-gamma), on the onset of AEC was investigated using both the IFN-gamma and the IFN-gamma receptor gene knockout mice, NOD.IFN-gamma(-/-) and NOD.IFN-gammaR(-/-), respectively. Neither the NOD.IFN-gamma(-/-) nor the NOD.IFN-gammaR(-/-) mice exhibited increased acinar cell apoptosis and abnormal salivary protein expression, typically observed in parental NOD mice prior to disease. Without these preimmune phase abnormalities, NOD.IFN-gamma(-/-) and NOD.IFN-gammaR(-/-) mice showed no subsequent autoimmune responses against the salivary glands at 20 weeks. Interestingly, real-time polymerase chain reaction and electrophoretic gel mobility shift assays suggested that IFN-gamma and STAT1, as well as the transcriptional activity of STAT1 in NOD glands, were increased at birth. Unlike the neonatal submandibular glands of NOD or NOD-scid mice that show abnormal glandular morphogenesis at birth, the submandibular glands of the newly constructed congenic strain, NOD-scid.IFN-gamma(-/-), were found to be normal. Taken together, IFN-gamma appears to play a critical role not only during the later immune phase of AEC, but also the early preimmune phase, independent of effector functions of immune cells. How exactly IFN-gamma functions during this period remains speculative.

  17. Symptoms of Parkinson's

    Science.gov (United States)

    ... Primary Motor Symptoms Secondary Motor Symptoms Nonmotor Symptoms Causes Progression Medications & Treatments Clinical Trials Statistics on Parkinson's What's New In Parkinson's Research? What's in the ...

  18. Premenstrual Syndrome (PMS) FAQ

    Science.gov (United States)

    ... syndrome irritable bowel syndrome thyroid disease Depression and anxiety disorders are the most common conditions that overlap with PMS. About one half of women seeking treatment for PMS have one of these ...

  19. Premenstrual dysphoric disorder

    Science.gov (United States)

    ... joint or muscle pain Problems sleeping Trouble concentrating Exams and Tests No physical examination or lab tests ... and little or no salt, sugar, alcohol, and caffeine. Get regular aerobic exercise throughout the month to ...

  20. Premenstrual breast changes

    Science.gov (United States)

    ... org/docs/3091546/Narrative/ . Accessed July 15, 2016. Katz VL, Dotters D. Breast diseases: diagnosis and treatment ... disease. In: Lentz GM, Lobo RA, Gershenson DM, Katz VL, eds. Comprehensive Gynecology . 6th ed. Philadelphia, PA: ...

  1. Premenstrual Dysphoric Disorder (PMDD)

    Science.gov (United States)

    ... Situations Pets and Animals myhealthfinder Food and Nutrition Healthy Food Choices Weight Loss and Diet Plans Nutrients and Nutritional Info Sugar and Sugar Substitutes Exercise and Fitness Exercise Basics Sports Safety Injury Rehabilitation Emotional Well- ...

  2. Premenstrual Syndrome (PMS)

    Science.gov (United States)

    ... as ginkgo, ginger, chasteberry, evening primrose oil and St. John's wort. However, few scientific studies have found that any ... or interact with other medications you're taking. St. John's wort, for example, reduces the effectiveness of birth control ...

  3. Multiple Myeloma Symptoms

    Science.gov (United States)

    ... Treatment Center Finder Home » About Multiple Myeloma » Symptoms Multiple Myeloma Symptoms Multiple myeloma symptoms may vary by patient, ... to be managed or prevented. The most common multiple myeloma symptoms may include: Bone pain or bone fractures ...

  4. General IC Symptoms

    Science.gov (United States)

    ... IC Symptoms of IC General IC Symptoms General IC Symptoms Symptoms of interstitial cystitis (IC) differ from ... news and events. Please leave this field empty Interstitial Cystitis Association 7918 Jones Branch Drive, Suite 300 McLean, ...

  5. Symptoms of Acoustic Neuroma

    Science.gov (United States)

    ... Programs & Services Search ANAUSA.org Connect with us! Symptoms of Acoustic Neuroma Each heading slides to reveal more information. Early Symptoms Early Symptoms Early symptoms are easily overlooked, thus making diagnosis ...

  6. Ambivalent sexism, attitudes towards menstruation and menstrual cycle-related symptoms.

    Science.gov (United States)

    Marván, Ma Luisa; Vázquez-Toboada, Rocío; Chrisler, Joan C

    2014-08-01

    The objective of the present study was to investigate the relationship between ambivalent sexism and beliefs and attitudes towards menstruation, and, in turn, to study the influence of these variables on menstrual cycle-related symptoms. One hundred and six Mexican women completed the Ambivalent Sexism Inventory, the Beliefs about and Attitudes toward Menstruation Questionnaire and the Menstrual Distress Questionnaire. The higher scores on benevolent sexism were associated with the most positive attitudes towards menstruation and also with the belief that a menstruating woman should or should not do some activities and that menstruation keeps women from their daily activities. The higher scores on hostile sexism were associated with rejection of menstruation as well as with feelings of embarrassment about it. Beliefs about and attitudes towards menstruation predicted menstrual cycle-related symptoms related to negative affect, impaired concentration and behavioural changes, but did not predict somatic symptoms. These results will be useful to health professionals and advocates who want to change the negative expectations and stereotypes of premenstrual and menstrual women and reduce the sexism and negative attitudes towards women that are evident in Mexican culture.

  7. Comportamento masculino diante da mulher com Síndrome Pré-Menstrual: narrativas de mulheres Comportamiento masculino delante de la mujer con Síndrome Premenstrual: narrativas de mujeres Male behavior in front of women with Premenstrual Syndrome: narratives of women

    Directory of Open Access Journals (Sweden)

    Luiza Akiko Komura Hoga

    2010-06-01

    Full Text Available OBJETIVO: Descrever as percepções de mulheres com Síndrome Pré-Menstrual a respeito do comportamento de seus parceiros diante delas. MÉTODOS: Pesquisa de abordagem qualitativa com desenvolvimento das cinco etapas do método de análise da narrativa para conhecer as representações a respeito dessa experiência. RESULTADOS: As experiências das 20 mulheres entrevistadas estão representadas nas categorias: Dificuldades para identificar a síndrome e adotar práticas de cuidado; Falta de conhecimento e sensibilidade dos homens e suas consequências sobre a relação entre o casal. CONCLUSÃO: Orientações sistematizadas sobre a Síndrome Pré-Menstrual devem ser fornecidas a todas as pessoas, em momento anterior à menarca, para evitar o surgimento de problemas decorrentes do desconhecimento da síndrome e suas consequências nas esferas pessoal, familiar e social das mulheres.OBJETIVO: Describir las percepciones de las mujeres con Síndrome Premenstrual a respecto del comportamiento de sus compañeros delante de ellas. MÉTODOS: Investigación de abordaje cualitativo con desarrollo de las cinco etapas, del método análisis de narrativa, para conocer las representaciones a respecto de esa experiencia. RESULTADOS: Las experiencias de las 20 mujeres entrevistadas están representadas en las categorías: Dificultades para identificar el síndrome y adoptar prácticas de cuidado; falta de conocimiento y de sensibilidad de los hombres y, sus consecuencias sobre la relación de la pareja. CONCLUSIÓN: Es necesario ofrecer orientaciones sistematizadas sobre el Síndrome Premenstrual a todas las personas, en un momento anterior a la menarca, para evitar el surgimiento de problemas provenientes del desconocimiento del síndrome y de sus consecuencias en las esferas personal, familiar y social de las mujeres.OBJECTIVE: To describe the perceptions of women with premenstrual syndrome regarding the behavior of their spouses in face of this event

  8. Comparison of serum zinc concentrations and body antioxidant status between young women with premenstrual syndrome and normal controls: A case-control study

    Science.gov (United States)

    Fathizadeh, Sanaz; Amani, Reza; Haghighizadeh, Mohammad Hossein; Hormozi, Razieh

    2016-01-01

    Background: Premenstrual syndrome (PMS) is one of the important health problems with high incidence in young women. The exact cause of this syndrome is not clear and some theories have been declared from hormonal factors to nutritional disorders. Objective: We investigated the correlation between serum zinc and antioxidant status with PMS. Materials and Methods: In this case-control study, forty eight young girls were selected from a total sample of 110 students residing at university dormitories including PMS (n=23) and healthy (n=25) groups based on PMS questionnaire. Dietary intake questionnaire and blood samples were collected from all participants. Serum total antioxidant capacity (TAC) and zinc concentrations were also measured. Results: Serum TAC and zinc concentrations were lower in PMS patients compared with healthy groups (p<0.01 and p<0.05, respectively). Healthy controls consumed lower servings of hydrogenated oils (p<0.05). There were significant differences in terms of muscle mass between the PMS and healthy groups (p<0.05). Both serum TAC and zinc levels were negatively correlated to PMS scores (r=-0.39, p<0.05 and r= -0.36; p<0.05, respectively). Conclusion: This study shows that higher TAC and zinc serum levels are associated with lower risk of PMS. PMS cases have more hydrogenated oils than their normal counterparts. PMID:27981255

  9. Pilot investigation of the circadian plasma melatonin rhythm across the menstrual cycle in a small group of women with premenstrual dysphoric disorder.

    Science.gov (United States)

    Shechter, Ari; Lespérance, Paul; Ng Ying Kin, N M K; Boivin, Diane B

    2012-01-01

    Women with premenstrual dysphoric disorder (PMDD) experience mood deterioration and altered circadian rhythms during the luteal phase (LP) of their menstrual cycles. Disturbed circadian rhythms may be involved in the development of clinical mood states, though this relationship is not fully characterized in PMDD. We therefore conducted an extensive chronobiological characterization of the melatonin rhythm in a small group of PMDD women and female controls. In this pilot study, participants included five women with PMDD and five age-matched controls with no evidence of menstrual-related mood disorders. Participants underwent two 24-hour laboratory visits, during the follicular phase (FP) and LP of the menstrual cycle, consisting of intensive physiological monitoring under "unmasked", time-isolation conditions. Measures included visual analogue scale for mood, ovarian hormones, and 24-hour plasma melatonin. Mood significantly (P≤.03) worsened during LP in PMDD compared to FP and controls. Progesterone was significantly (P = .025) increased during LP compared to FP, with no between-group differences. Compared to controls, PMDD women had significantly (Pcircadian phases spanning the biological night during both menstrual phases and reduced amplitude of its circadian rhythm during LP. PMDD women also had reduced area under the curve of melatonin during LP compared to FP. PMDD women showed affected circadian melatonin rhythms, with reduced nocturnal secretion and amplitude during the symptomatic phase compared to controls. Despite our small sample size, these pilot findings support a role for disturbed circadian rhythms in affective disorders. Possible associations with disrupted serotonergic transmission are proposed.

  10. Glaucoma: Symptoms, Diagnosis & Treatment

    Science.gov (United States)

    ... this page please turn JavaScript on. Feature: Glaucoma Symptoms, Treatment and Research Past Issues / Spring 2015 Table ... without any pain. Photo courtesy of NEI Glaucoma Symptoms At first, open-angle glaucoma has no symptoms. ...

  11. Symptoms and Diagnosis

    Science.gov (United States)

    ... Differential Disorders Frequently Asked Questions Glossary Downloadable Publications Symptoms and Diagnosis If you are new to dystonia, it can ... be accounted for: ► The age at which the symptoms started. The age at which symptoms begin is ...

  12. 埋线配合穴位按压治疗经前期综合征疗效观察%Observation of the effect of catgut implantation combined with acupressure on premenstrual syndrome

    Institute of Scientific and Technical Information of China (English)

    谭秀芬; 林玉敏

    2015-01-01

    目的:观察埋线配合穴位按压治疗经前期综合征( PMS)的临床疗效。方法将108例PMS患者随机分为治疗组和对照组各54例,治疗组采用埋线配合穴位按压疗法;对照组予以口服中成药逍遥丸。治疗3个月经周期,观察治疗前后2组临床症状、基础体温( BBT)变化情况。结果纳入108例患者,104例完成试验,脱落4例。治疗组52例患者,痊愈6例,显效23例,有效18例,无效5例,总有效率90%;对照组52例患者,痊愈3例,显效10例,有效24例,无效15例,总有效率71%。治疗后2组总疗效比较差异有统计学意义(P<0.01)。结论埋线配合穴位按压疗法具有疗效高、见效快、安全无不良反应、患者依从性高的特点,治疗PMS的临床疗效显著优于中成药,值得临床推广应用。%Objective It is to observe the clinical curative effect of catgut implantation combined with acupressure on pre-menstrual syndrome ( PMS) .Methods 108 patients with PMS were randomly divided into treatment group and control group with 54 cases in each group.The treatment group was treated with catgut implantation combined with acupressure, while the control group was treated with Xiaoyao pills by oral administration.After 3 menstrual cycle’ s treatment, the changes of clinical symptoms and BBT before and after treatment in both groups were observed.Results In the 108 patients selected, there were 104 cases completed the study, and 4 cases lost.In the treatment group, there were 52 cases in which there were 6 curing ca-ses, 23 excellent cases, 18 effective cases, 5 non-effective cases, the total effective rate was 90%;In the control group, there were 52 cases in which there were 3 curing cases, 10 excellent cases, 24 effective cases, 15 non-effective cases, the total ef-fective rate was 71%.The difference in the total effect between the two groups were significant (P<0.01).Conclusion The therapy with catgut

  13. Pilot investigation of the circadian plasma melatonin rhythm across the menstrual cycle in a small group of women with premenstrual dysphoric disorder.

    Directory of Open Access Journals (Sweden)

    Ari Shechter

    Full Text Available Women with premenstrual dysphoric disorder (PMDD experience mood deterioration and altered circadian rhythms during the luteal phase (LP of their menstrual cycles. Disturbed circadian rhythms may be involved in the development of clinical mood states, though this relationship is not fully characterized in PMDD. We therefore conducted an extensive chronobiological characterization of the melatonin rhythm in a small group of PMDD women and female controls. In this pilot study, participants included five women with PMDD and five age-matched controls with no evidence of menstrual-related mood disorders. Participants underwent two 24-hour laboratory visits, during the follicular phase (FP and LP of the menstrual cycle, consisting of intensive physiological monitoring under "unmasked", time-isolation conditions. Measures included visual analogue scale for mood, ovarian hormones, and 24-hour plasma melatonin. Mood significantly (P≤.03 worsened during LP in PMDD compared to FP and controls. Progesterone was significantly (P = .025 increased during LP compared to FP, with no between-group differences. Compared to controls, PMDD women had significantly (P<.05 decreased melatonin at circadian phases spanning the biological night during both menstrual phases and reduced amplitude of its circadian rhythm during LP. PMDD women also had reduced area under the curve of melatonin during LP compared to FP. PMDD women showed affected circadian melatonin rhythms, with reduced nocturnal secretion and amplitude during the symptomatic phase compared to controls. Despite our small sample size, these pilot findings support a role for disturbed circadian rhythms in affective disorders. Possible associations with disrupted serotonergic transmission are proposed.

  14. Gout: Symptoms, Diagnosis & Treament

    Science.gov (United States)

    ... Javascript on. Feature: Detecting and Treating Gout Gout: Symptoms, Diagnosis & Treament Past Issues / Winter 2012 Table of Contents ... Gout may be difficult to diagnose because the symptoms can be vague and could be from other ...

  15. Pertussis Signs & Symptoms

    Science.gov (United States)

    ... of Kids with Infectious Diseases (PKIDs) Signs and Symptoms Language: English Español (Spanish) Recommend on Facebook Tweet ... not for as long as 3 weeks. Early Symptoms In those who have been vaccinated: In most ...

  16. PTSD: Symptoms, Diagnosis, Treatment

    Science.gov (United States)

    ... Bar Home Current Issue Past Issues Feature PTSD Symptoms, Diagnosis , Treatment Past Issues / Winter 2009 Table of Contents ... version of this page please turn Javascript on. Symptoms As with mild traumatic brain injury (TBI), PTSD ...

  17. Prostate Cancer Symptoms

    Science.gov (United States)

    ... Patient Support Guides Why no symptoms? Because prostate cancer hardly ever starts in the most convenient part of the prostate for symptoms to occur, near the urethra (the tube that carries urine through the prostate ...

  18. Psychiatric symptoms as pathogens

    NARCIS (Netherlands)

    van den Hout, Marcel

    2014-01-01

    Disorders are typically seen as the causes of their symptoms. This makes sense in many fields of medicine, but not in psychiatry where symptoms constitute disorders: the notion that mental disorders cause symptoms is a tautology. Biological psychiatry tries to circumvent this logical fallacy by tryi

  19. Understanding medical symptoms

    DEFF Research Database (Denmark)

    Malterud, Kirsti; Guassora, Ann Dorrit Kristiane; Graungaard, Anette Hauskov

    2015-01-01

    The aim of this article is to present a conceptual review and analysis of symptom understanding. Subjective bodily sensations occur abundantly in the normal population and dialogues about symptoms take place in a broad range of contexts, not only in the doctor’s office. Our review of symptom unde...

  20. Symptoms of Ovarian Cancer

    Science.gov (United States)

    ... Informed Cancer Home What Are the Symptoms of Ovarian Cancer? Language: English Español (Spanish) Recommend on Facebook Tweet Share Compartir Gynecologic cancer symptoms diaries Ovarian cancer may cause the following signs and symptoms— Vaginal ...

  1. Management of somatic symptoms

    DEFF Research Database (Denmark)

    Schröder, Andreas; Dimsdale, Joel

    2014-01-01

    on the recognition and effective management of patients with excessive and disabling somatic symptoms. The clinical presentation of somatic symptoms is categorized into three groups of patients: those with multiple somatic symptoms, those with health anxiety, and those with conversion disorder. The chapter provides...

  2. Initial Symptoms of ALS

    Science.gov (United States)

    ... Research In Your Community Advocate Get Involved Donate Symptoms and Diagnosis En español Symptoms The initial symptoms of ALS can be quite ... the eyes and bladder are generally not affected. Diagnosis ALS is a difficult disease to diagnose. There ...

  3. Consequências da síndrome da tensão pré-menstrual na vida da mulher Consequencias de la sindrome de la tension pre-menstrual en la vida de la mujer The consequences of the syndrome of the pre-menstrual tension in the woman's life

    Directory of Open Access Journals (Sweden)

    Clarice H. Muramatsu

    2001-09-01

    Full Text Available Este estudo tem como objetivo identificar as possíveis conseqüências da Síndrome da Tensão Pré-Menstrual na vida da mulher. Através do questionário, identificamos distúrbios relacionados a alterações físicas, emocionais e, como consequências às alterações nos relacionamentos envolvendo filho, marido/ namorado e familiar, assim como no ambiente de trabalho.Este estudio tuvo como objetivo identificar las posibles consequencias de la sindrome de la tensión pre-menstrual en la vida de la mujer. Atraves de un questionário, identificamos disturbios relacionados con alteraciones físicas y emocionales que por vez danãn los relacionamentos envolviendo hijo, marido, enamorado y familiares, asi como en el ambiente de trabajo.This study has as objective to identify the possible consequences of the Syndrome of the Pré-menstrual Tension in the woman's life. Through the questionnaire, we identified disturb related to physical and emotional discomfort and as consequences the alterations in the relationships involving son, husband / boyfriend and family, as well as in the work atmosphere.

  4. Association of self-reported symptoms with serum levels of vitamin D and multivariate cytokine profile in healthy women

    Science.gov (United States)

    Azizieh, Fawaz Y; Alyahya, Khulood O; Dingle, Kamaludin

    2017-01-01

    Background Although a large number of studies have investigated possible relationships among serum levels of vitamin D or cytokines with disease progress and prognosis, similar studies on self-reported symptoms are still controversial. The overall objective of this study was to look into the association between serum levels of vitamin D or cytokines with self-reported symptoms related to musculoskeletal pain, sleep disorders, and premenstrual syndrome (PMS) in healthy adult women. Subjects and methods Venous blood samples were collected from 117 healthy adult women, and serum levels of vitamin D, pro-inflammatory cytokines (IL-1β, IL-6, IL-8, IL-17, IFN-γ, and TNF-α) and anti-inflammatory cytokines (IL-4, IL-10, and IL-13) were measured. Groups were tested for differences in single parameters, pro-:anti-inflammatory cytokine ratios, and differences in multivariate patterns. Results There were no significant associations between serum levels of vitamin D and any of the self-reported symptoms studied. However, serum levels of certain pro-inflammatory cytokines were significantly higher in subjects with musculoskeletal pain (IL-8, P=0.008), sleep disorders (IFN-γ, P=0.02), and PMS (IL-8 and TNF-α, P=0.009 and 0.002, respectively) compared to subjects who reported no symptoms. The pro-:anti-inflammatory cytokine ratios showed pro-inflammatory cytokine dominance in subjects with self-reported symptoms, particularly in the groups with deficient levels of vitamin D. However, the multivariate cytokine-pattern analysis was significantly different between PMS groups only. Conclusion These data point to a possible role of pro-inflammatory cytokines as a contributing factor in self-reported symptoms related to musculoskeletal pain, sleep disorders, and PMS.

  5. Musculoskeletal symptoms among electricians.

    Science.gov (United States)

    Hunting, K L; Welch, L S; Cuccherini, B A; Seiger, L A

    1994-02-01

    This study ascertained the presence of musculoskeletal symptoms among electricians, in order to evaluate the prevalence of cumulative trauma disorders (CTD) in this population. We adapted the CTD surveillance questionnaire used by National Institute for Occupational Safety and Health (NIOSH) to assess the prevalence of neck, shoulder, elbow, hand/wrist, back, and knee symptoms in the year prior to the survey. Questionnaires were completed by 308 apprentices and journeymen enrolled in training classes at the local union hall. The participants were relatively young individuals, and 86% of the participants were currently working as electricians. Participants reported a high prevalence of symptoms which occurred more than three times during the past year or which lasted more than 1 week. Back symptoms and hand/wrist symptoms were experienced most frequently, by about half the population, while elbow symptoms were reported by only 15% of participants. Symptom prevalence was lower, but still notable, when defined as symptoms which had occurred at least once a month or lasted more than a week in the past year. Eighty-two percent of participants reported at least one musculoskeletal symptom using the most inclusive definition, while 57% reported two or more symptoms. This survey highlights that: 1) low back discomfort is common in young construction workers, and resulted in medical care, missed work, or light duty for almost 35% of the participants; 2) neck discomfort is also very common and required doctor visits or work modification for almost one quarter of the participants; 3) these construction workers continued to work with symptoms that are classifiable as a CTD; and 4) history of injury is correlated with the subsequent prevalence of musculoskeletal symptoms.

  6. Management of somatic symptoms

    DEFF Research Database (Denmark)

    Schröder, Andreas; Dimsdale, Joel

    2014-01-01

    on the recognition and effective management of patients with excessive and disabling somatic symptoms. The clinical presentation of somatic symptoms is categorized into three groups of patients: those with multiple somatic symptoms, those with health anxiety, and those with conversion disorder. The chapter provides...... information to assist with making a diagnosis and differential diagnosis. Management includes ways to improve the physician–patient interaction that will benefit the patient, a step-care model based on illness severity and complexity, and psychological and pharmacologic treatment. The chapter is enhanced...... by figures and tables that summarize health anxiety, symptoms, differential diagnoses, and management strategies, as well as by case studies and examples....

  7. Chronic Fatigue Syndrome (CFS): Symptoms

    Science.gov (United States)

    ... CDC.gov . Chronic Fatigue Syndrome (CFS) Share Compartir Symptoms On this Page Primary Symptoms Other Symptoms What's ... a doctor distinguish CFS from other illnesses. Primary Symptoms As the name chronic fatigue syndrome suggests , fatigue ...

  8. Tratamento da disforia pré-menstrual com antidepressivos: revisão dos ensaios clínicos controlados Treatment of premenstrual dysphoria with antidepressants: review of controlled clinical trials

    Directory of Open Access Journals (Sweden)

    Elie Cheniaux

    2006-01-01

    Full Text Available INTRODUÇÃO: A disforia pré-menstrual (DPM, que acomete entre 3% e 8% das mulheres em idade fértil, representa uma forma mais grave de síndrome pré-menstrual, na qual predominam as alterações do humor e do comportamento. Acredita-se que haja algum tipo de ligação entre a DPM e os transtornos do humor. OBJETIVO: Estudar a eficácia dos antidepressivos na DPM. MÉTODOS: Foi realizada uma revisão dos ensaios clínicos controlados com antidepressivos no tratamento da DPM, utilizando-se as seguintes bases de dados: Medline, Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS, psycINFO e Biblioteca Cochrane. RESULTADOS: A clomipramina, a fluoxetina, a sertralina, a paroxetina e a venlafaxina se mostraram superiores ao placebo em diversos estudos. DISCUSSÃO: As mulheres que sofrem de DPM possivelmente apresentam uma disfunção serotoninérgica. CONCLUSÃO: Alguns antidepressivos, especialmente os inibidores seletivos da recaptação da serotonina (ISRS, parecem ser eficazes no tratamento da DPM.INTODUCTION: Premenstrual dysphoria (PMD, which affects between 3% and 8% of women during reproductive years, represents a more severe type of premenstrual syndrome. Mood and behavior changes are predominant in PMD. It is believed that there is some kind of link between PMS and mood disorders. OBJECTIVE: Studying the efficacy of antidepressants in PMD. METHODS: We elaborated a review of controlled clinical trials with antidepressants in the treatment of PMD, using the following databases: Medline, LILACS, psycINFO and Cochrane Library. RESULTS: Clomipramine, fluoxetine, sertraline, paroxetine and venlafaxine were superior to placebo in various studies. DISCUSSION: Women with PMD possibly present a serotonergic dysfunction. CONCLUSION: Some antidepressants, specialy SSRIs, seem to be effective in the treatment of PMD.

  9. Gynecological cancer alarm symptoms:

    DEFF Research Database (Denmark)

    Balasubramaniam, Kirubakaran; Ravn, Pernille; dePont Christensen, René

    2016-01-01

    INTRODUCTION: To determine the proportion of patients who were referred to specialist care after reporting gynecological cancer alarm symptoms to their general practitioner. To investigate whether contact with specialist care was associated with lifestyle factors or socioeconomic status. MATERIAL......: Educational level influence contact with specialist care among patients with gynecological cancer alarm symptoms. Future studies should investigate inequalities in access to the secondary healthcare system. This article is protected by copyright. All rights reserved.......INTRODUCTION: To determine the proportion of patients who were referred to specialist care after reporting gynecological cancer alarm symptoms to their general practitioner. To investigate whether contact with specialist care was associated with lifestyle factors or socioeconomic status. MATERIAL...... and odds ratios (ORs) for associations between specialist care contact, lifestyle factors and socioeconomic status. RESULTS: The study included 25 866 non-pregnant women; 2957 reported the onset of at least one gynecological cancer alarm symptom, and 683 of these (23.1%) reported symptoms to their general...

  10. Numb Chin Syndrome as First Symptom of Diffuse Large B-Cell Lymphoma

    Directory of Open Access Journals (Sweden)

    Mario Carbone

    2014-01-01

    Full Text Available Numb chin syndrome is a rare sensory neuropathy of the mental nerve characterized by numbness, hypoesthesia, paraesthesia, and very rarely pain. Dental causes, especially iatrogenic ones, maxillofacial trauma, or malignant neoplasm are etiologic factors for this rare syndrome. Many malignant and metastatic neoplasms are causing this syndrome, like primary osteosarcoma, squamous cell carcinoma, and mandibular metastasis of primary carcinoma of breast, lung, thyroid, kidney, prostate, and nasopharynx. Haematological malignancies like acute lymphocytic leukaemia, Hodgkin and non-Hodgkin lymphoma, and myeloma can cause this neuropathy. The authors report a case of a 71-year-old woman in which the numb chin syndrome was the first symptom of the diffuse large B-cell lymphoma, which caused infiltration and reabsorption of the alveolar ridge and lower mandibular cortex. A biopsy of the mass was performed on fragments of tissue collected from the mandibular periosteum, medullary and cortical mandibular bone, and inferior alveolar nerve.

  11. Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD)

    Science.gov (United States)

    ... have ever been treated for a mood or anxiety disorder, substance abuse, headaches, chronic fatigue or other medical conditions that can sometimes get worse a few days before a women’s menstrual period. Is there anything I can do ...

  12. Dermatomyositis: Signs and Symptoms

    Science.gov (United States)

    ... Meet our Partners How to Get Involved Donate Dermatomyositis (DM) Share print email share facebook twitter google ... Signs and Symptoms What happens to someone with dermatomyositis? For many decades, DM was considered “ polymyositis with ...

  13. Medically Unexplained Symptoms

    Science.gov (United States)

    ... may flare up or worsen. IRRITABLE BOWEL SYNDROME Irritable Bowel Syndrome (IBS) is an MUS that interferes with the normal functioning of the large intestine. It is characterized by a group of symptoms, ...

  14. Symptoms of Blood Disorders

    Science.gov (United States)

    ... leg (causing most often swelling, redness, and/or warmth of the leg or shortness of breath) Petechiae ( ... Disorders Symptoms of Blood Disorders Medical History and Physical Examination for Blood Disorders Laboratory Tests for Blood ...

  15. Throat Problems (Symptom Checker)

    Science.gov (United States)

    ... your doctor.Start OverDiagnosisThese symptoms may be from BRONCHITIS, PNEUMONIA or POST-NASAL DRIP.Self CareThese illnesses need prescription treatments. See your doctor.Start OverDiagnosisA dry barking cough ...

  16. Duration of symptoms

    DEFF Research Database (Denmark)

    Hansen, Olfred; Larsen, Susanne; Bastholt, Lars

    2005-01-01

    PURPOSE: To study the relationship between the durations of symptoms before the start of radiotherapy and treatment outcome in Stage I-III glottic cancer. METHODS AND MATERIALS: From 1965 to 1997, 611 glottic cancer patients from the Southern Region of Denmark were treated with primary radiotherapy....... A total of 544 patients fulfilled the criteria for inclusion to the study (Stage I-III glottic cancer, a duration of symptoms less than or equal to 36 months, primary radiotherapy with at least 50 Gy and sufficient data for analysis). The total radiation dose ranged from 50.0 to 71.6 Gy in 22 to 42...... of symptoms was a significant factor (p symptoms was statistically...

  17. Symptoms of Tickborne Illness

    Science.gov (United States)

    ... Removing a tick Symptoms of tickborne illness Geographic distribution of ticks that bite humans How ticks spread ... varies greatly from person to person in appearance, location, and time of onset. About 10% of people ...

  18. Tetanus: Symptoms and Complications

    Science.gov (United States)

    ... Search The CDC Cancel Submit Search The CDC Tetanus Note: Javascript is disabled or is not supported ... message, please visit this page: About CDC.gov . Tetanus Home About Tetanus Causes and Transmission Symptoms and ...

  19. Correlations among insomnia symptoms, sleep medication use and depressive symptoms

    National Research Council Canada - National Science Library

    Komada, Yoko; Nomura, Takashi; Kusumi, Masayoshi; Nakashima, Kenji; Okajima, Isa; Sasai, Taeko; Inoue, Yuichi

    2011-01-01

    Aim:  To elucidate the factors associated with insomnia symptoms and the use of sleep medication, and the correlations among insomnia symptoms, sleep medication use and depressive symptoms in the general population. Methods...

  20. Menopause: Symptom Relief and Treatments

    Science.gov (United States)

    ... Submit Home > Menopause > Menopause symptom relief and treatments Menopause Menopause symptom relief and treatments Working with your doctor ... on menopause symptom relief and treatments Learning about menopause treatment options Most women do not need treatment ...

  1. Symptoms of Lewy Body Dementia

    Science.gov (United States)

    ... Treatment Options Join the fight against LBD! Donate Symptoms Lewy body dementia symptoms and diagnostic criteria Every person with LBD is ... or Dementia plus one or more suggestive features. Symptoms Explained In this section we'll discuss each ...

  2. Headache Symptoms, Diagnosis, and Treatment

    Science.gov (United States)

    ... Current Issue Past Issues Headaches and Migraines Headache Symptoms, Diagnosis, and Treatment Past Issues / Spring 2009 Table of ... symptoms and treatments. Migraine and Other Vascular Headaches—Symptoms and Diagnosis Migraine: The most common of vascular ...

  3. Cooperation and depressive symptoms.

    Science.gov (United States)

    Brendan Clark, C; Thorne, Christopher B; Hardy, Sonya; Cropsey, Karen L

    2013-09-25

    Deficits in pro-social cooperation are common in many individuals with mental illnesses such as depression. For decades, researchers have used economic game paradigms to compare cross-cultural cooperative behavior. However, research using economic games to assess cooperative behavior in clinical populations is in the early stages. We hypothesized that individuals with greater depressive symptoms would struggle to maintain reciprocity in iterative games, but not in single-iteration games measuring personal values. Participants (n=41) played four computer-based economic games (prisoner's dilemma, the public goods game, the ultimatum game, and the trust game) measuring different aspects of cooperation. Participants completed the Depression Anxiety and Stress Scale (DASS) and other measures of personality and demographics. Analyses assessed the relationships between game performance and psychological distress as measured by the DASS. Significant correlations were found between game performance and depressive symptoms, but not symptoms of anxiety or stress. Performance in the prisoner's dilemma and public goods game was significantly related to depression in a linear regression even when known associations with depressive affect such as age, gender, race, education, marital status, and neuroticism were controlled for. Depressive symptoms were associated with an inability to sustain reciprocal cooperation. Participants showed the predicted deficits in cooperation in these economic games. Economic games show the potential for assessing the social deficits associated with depressive symptoms. © 2013 Elsevier B.V. All rights reserved.

  4. Social Sensations of Symptoms:

    DEFF Research Database (Denmark)

    Meinert, Lotte; Whyte, Susan Reynolds

    2016-01-01

    The interpretation of sensations and the recognition of symptoms of a sickness, as well as the movement to seek treatment, have long been recognized in medical anthropology as inherently social processes. Based on cases of HIV and trauma (PTSD) in Uganda, we show that even the first signs...... and sensations of sickness can be radically social. The sensing body can be a ‘social body’ – a family, a couple, a network – a unit that transcends the individual body. In this article we focus on four aspects of the sociality of sensations and symptoms: mode of transmission; the shared experience of sensations...

  5. 大学生睡眠质量与经前期烦躁障碍%Sleep quality in university students with Premenstrual Dysphoric Disorder

    Institute of Scientific and Technical Information of China (English)

    Habibolah KHAZAIE; Mohammad Rasoul GHADAMI; Behnam KHALEDI-PAVEH; Azita CHEHRI; Marzieh NASOURI

    2016-01-01

    Background:Up to 8% of women in their reproducitve years are affected by Premenstral Dysphoric Disorder (PMDD). Sleep disturbances such as insomnia or hypersomnia are one of the DSM-IV-TR’s deifning criteria for the diagnosis of PMDD and are found in about 70% of women with the disorder. However, studies are lacking that speciifcally address the effects of PMDD on quality of sleep. Aim:This study was designed to evaluate the prevalence of Premenstrual DysphoricDisorder (PMDD) and its impact on sleep quality in female university students. Methods:We developed an 18-item PMDD scale based on The Diagnositc and Staitsitcal Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) to diagnose PMDD in female university studentswho ranged in age from 18 to 30 years and had regular menstrual cycles.Paritcipants were categorized into a PMDD group or a No/PMDD group and sleep quality was compared between the two groups. The evaluaiton tool used to measure sleep quality was the Pittsburgh Sleep Quality Index (PSQI). Results:The prevalence of PMDD in female universitystudents was 25.5%. Analysis of the PSQI demonstrated that 80.5% of those in PMDD group had a PSQI that scored >5; however, only 56.4% in the No/PMDD grouphad a PSQI that scored >5 (χ2=12.459,p<0.001). The mean PSQI score was 8.2(3.4) in the PMDD group and was 6.5(3.1) in the No/PMDD group (t=3.648,p<0.001). Conclusions:Female university students who experience PMDD are deeply affected by sleep problems. Lower sleep quality, dayitme dysfunciton, and sleep disturbance are common sleep problems among female university students with PMDD.%背景:高达8%的育龄妇女受经前期烦躁障碍(PMDD)所困。DSM-IV-TR把失眠或嗜睡等睡眠紊乱作为PMDD的诊断标准之一。大约70%的PMDD患者存在睡眠紊乱。然而,专注解决PMDD对睡眠质量影响的有关研究却非常缺乏。目标:本研究旨在评估女大学生中PMDD的患病率及其对睡眠质量的影响。

  6. Symptoms of Celiac Disease

    Science.gov (United States)

    ... enamel • Unexplained infertility, recurrent miscarriage • Osteopenia (mild) or osteoporosis (more serious bone density problem) • Peripheral Neuropathy • Psychiatric disorders such as anxiety, depression How do these symptoms tend to appear in children and adults? Children tend to have the more classic signs ...

  7. Emotional symptoms among adolescents

    DEFF Research Database (Denmark)

    Meilstrup, Charlotte; Ersbøll, Annette K; Nielsen, Line

    2015-01-01

    . A negative classroom climate was associated with emotional symptoms (OR 1.29, 95% CI: 0.99-1.69) and so was being part of classrooms with a high prevalence of bullying (OR 1.28, 95% CI: 1.0-1.60). CONCLUSION: Female sex, low OSC, single parent family, exposure to bullying and a high prevalence of bullying...

  8. Bullying and PTSD Symptoms

    Science.gov (United States)

    Idsoe, Thormod; Dyregrov, Atle; Idsoe, Ella Cosmovici

    2012-01-01

    PTSD symptoms related to school bullying have rarely been investigated, and never in national samples. We used data from a national survey to investigate this among students from grades 8 and 9 (n = 963). The prevalence estimates of exposure to bullying were within the range of earlier research findings. Multinomial logistic regression showed that…

  9. FORSTÅ DINE SYMPTOMER

    DEFF Research Database (Denmark)

    Christensen, Kaj Aage Sparle

    Hvis du tit har smerter og andre fysiske symptomer - og lægen har svært ved at finde ud af, hvad du fejler - kan det være, du har en funktionel lidelse. Funktionel lidelse betyder, at kroppen reagerer medsymptomer, når du er udsat for psykiske belastninger. Symptomerne er lige så virkelige og...

  10. Symptoms%症状

    Institute of Scientific and Technical Information of China (English)

    Jerome K. Jerome; 孙宝成; 徐彬

    2004-01-01

    @@ It was my liver that was out of order. I knew it was my liver that was out of order, because I had just been reading a patent liver-pill circular1, in which were detailed the various symptoms by which a man could tell when his liver was out of order. I had them all.

  11. Premonitory symptoms in migraine

    DEFF Research Database (Denmark)

    Laurell, Katarina; Artto, Ville; Bendtsen, Lars

    2016-01-01

    AIM: To describe the frequency and number of premonitory symptoms (PS) in migraine, the co-occurrence of different PS, and their association with migraine-related factors. METHODS: In this cross-sectional study, a validated questionnaire was sent to Finnish migraine families between 2002 and 2013...

  12. Pathways from maternal depressive symptoms to adolescent depressive symptoms:the unique contribution of irritability symptoms

    OpenAIRE

    Whelan, Y.M.; Leibenluft, E.; Stringaris, A; Edward D Barker

    2015-01-01

    BACKGROUND: The authors tested three possible pathways linking prenatal maternal depressive symptoms to adolescent depressive symptoms. These pathways went through childhood Irritability Symptoms, Anxiety/Depressive Symptoms or Conduct Problems.METHOD: Data were collected from 3,963 mother-child pairs participating in the Avon Longitudinal Study of Parents and Children. Measures include maternal depressive symptoms (pre- and postnatal); toddler temperament (2 years); childhood (7-13 years) ir...

  13. Hearing symptoms personal stereos

    Science.gov (United States)

    da Luz, Tiara Santos; Borja, Ana Lúcia Vieira de Freitas

    2012-01-01

    Summary Introduction: Practical and portable the personal stereos if had become almost indispensable accessories in the day the day. Studies disclose that the portable players of music can cause auditory damages in the long run for who hear music in high volume for a drawn out time. Objective: to verify the prevalence of auditory symptoms in users of amplified players and to know its habits of use Method: Observational prospective study of transversal cut carried through in three institutions of education of the city of Salvador BA, being two of public net and one of the private net. 400 students had answered to the questionnaire, of both the sex, between 14 and 30 years that had related the habit to use personal stereos. Results: The symptoms most prevalent had been hyperacusis (43.5%), auricular fullness (30.5%) and humming (27.5), being that the humming is the symptom most present in the population youngest. How much to the daily habits: 62.3% frequent use, 57% in raised intensities, 34% in drawn out periods. An inverse relation between exposition time was verified and the band of age (p = 0,000) and direct with the prevalence of the humming. Conclusion: Although to admit to have knowledge on the damages that the exposition the sound of high intensity can cause the hearing, the daily habits of the young evidence the inadequate use of the portable stereos characterized by long periods of exposition, raised intensities, frequent use and preference for the insertion phones. The high prevalence of symptoms after the use suggests a bigger risk for the hearing of these young. PMID:25991931

  14. Hearing symptoms personal stereos

    Directory of Open Access Journals (Sweden)

    Tiara Santos da Luz1

    2012-01-01

    Full Text Available Introduction: Practical and portable the personal stereos if had become almost indispensable accessories in the day the day. Studies disclose that the portable players of music can cause auditory damages in the long run for who hear music in high volume for a drawn out time. Objective: to verify the prevalence of auditory symptoms in users of amplified players and to know its habits of use. Method: Observational prospective study of transversal cut carried through in three institutions of education of the city of Salvador BA, being two of public net and one of the private net. 400 students had answered to the questionnaire, of both the sex, between 14 and 30 years that had related the habit to use personal stereos. Results: The symptoms most prevalent had been hyperacusis (43.5%, auricular fullness (30.5% and humming (27.5, being that the humming is the symptom most present in the population youngest. How much to the daily habits: 62.3% frequent use, 57% in raised intensities, 34% in drawn out periods. An inverse relation between exposition time was verified and the band of age (p=0,000 and direct with the prevalence of the humming. Conclusion: Although to admit to have knowledge on the damages that the exposition the sound of high intensity can cause the hearing, the daily habits of the young evidence the inadequate use of the portable stereos characterized by long periods of exposition, raised intensities, frequent use and preference for the insertion phones. The high prevalence of symptoms after the use suggests a bigger risk for the hearing of these young.

  15. [Depressive symptoms and sexuality].

    Science.gov (United States)

    Porto, Robert

    2014-10-01

    The mutually reinforcing dyad of depressive symptoms and erectile dysfunction is scientifically established. The cure of depression improves sexual dysfunction (SD) and the treatment of SD induces improvement of depression. Most of anti-depressants induce negative sexual side effects that lead to non-compliance of these treatments. The knowledge of interrelation between depression, anti-depressants and sexuality is of great importance in clinical practice. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  16. Neurobiology Underlying Fibromyalgia Symptoms

    Directory of Open Access Journals (Sweden)

    Marta Ceko

    2012-01-01

    Full Text Available Fibromyalgia is characterized by chronic widespread pain, clinical symptoms that include cognitive and sleep disturbances, and other abnormalities such as increased sensitivity to painful stimuli, increased sensitivity to multiple sensory modalities, and altered pain modulatory mechanisms. Here we relate experimental findings of fibromyalgia symptoms to anatomical and functional brain changes. Neuroimaging studies show augmented sensory processing in pain-related areas, which, together with gray matter decreases and neurochemical abnormalities in areas related to pain modulation, supports the psychophysical evidence of altered pain perception and inhibition. Gray matter decreases in areas related to emotional decision making and working memory suggest that cognitive disturbances could be related to brain alterations. Altered levels of neurotransmitters involved in sleep regulation link disordered sleep to neurochemical abnormalities. Thus, current evidence supports the view that at least some fibromyalgia symptoms are associated with brain dysfunctions or alterations, giving the long-held “it is all in your head” view of the disorder a new meaning.

  17. Therapeutics for multiple sclerosis symptoms.

    Science.gov (United States)

    Ben-Zacharia, Aliza Bitton

    2011-01-01

    Symptoms management in multiple sclerosis is an integral part of its care. Accurate assessment and addressing the different symptoms provides increased quality of life among patients with multiple sclerosis. Multiple sclerosis symptoms may be identified as primary, secondary, or tertiary symptoms. Primary symptoms, such as weakness, sensory loss, and ataxia, are directly related to demyelination and axonal loss. Secondary symptoms, such as urinary tract infections as a result of urinary retention, are a result of the primary symptoms. Tertiary symptoms, such as reactive depression or social isolation, are a result of the social and psychological consequences of the disease. Common multiple sclerosis symptoms include fatigue and weakness; decreased balance, spasticity and gait problems; depression and cognitive issues; bladder, bowel, and sexual deficits; visual and sensory loss; and neuropathic pain. Less-common symptoms include dysarthria and dysphagia, vertigo, and tremors. Rare symptoms in multiple sclerosis include seizures, hearing loss, and paralysis. Symptom management includes nonpharmacological methods, such as rehabilitation and psychosocial support, and pharmacological methods, ie, medications and surgical procedures. The keys to symptom management are awareness, knowledge, and coordination of care. Symptoms have to be recognized and management needs to be individualized. Multiple sclerosis therapeutics include nonpharmacological strategies that consist of lifestyle modifications, rehabilitation, social support, counseling, and pharmacological agents or surgical procedures. The goal is vigilant management to improve quality of life and promote realistic expectations and hope.

  18. 经前期综合征相关神经递质及其受体研究进展%Research Progress of Neurotransmitters and the Receptors Involved in Premenstrual Syndrome

    Institute of Scientific and Technical Information of China (English)

    高兴笑

    2011-01-01

    经前期综合征(PMS)的发病机制十分复杂,目前尚未完全明确,与该病可能相关的神经递质主要包括单胺类、氨基酸类和肽类.国内外已有研究表明PMS与单胺类(以5-羟色胺为主)及氨基酸类(以谷氨酸、氨酪酸为主)神经递质有关,但有关肽类对PMS影响的研究较少较浅.现对可能涉及该病的神经递质及其受体进行归类综述,以期为进一步探讨PMS神经生化方面的微观机制提供参考.%Pathogenesis of premenstrual syndrome is so complicated that a clear understanding of it is still missing. Neurotransmitters,which may have close relation to PMS,including monoamines,aminoacids and neuropeptides. Domestic and abroad researches have found that PMS is closely related to monoamines( 5-HE、 DA and NE )and aminoacids( GABA and Glu are of greater importance ),but studies on neuropeptides are less and supeificial. Here is to introduce the development of neurotransmitters and their receptors related to PMS according to their categories, with expectation to provide references on neural and biochemical micro-mechanism for PMS.

  19. Research progress on the treatment of premenstrual syndrome by oral contraceptive%口服避孕药治疗经前期综合征的研究进展

    Institute of Scientific and Technical Information of China (English)

    涂彬彬; 乔杰

    2009-01-01

    经前期综合征(premenstrual syndrome,PMS)是指月经来潮前周期性出现影响妇女日常生活和工作的躯体、精神及行为的一组症候群,发病率较高,目前病因尚不明确.其治疗主要包括非药物治疗和药物治疗.口服避孕药(oral contraceptive,OCP)由于其特殊性质近来被考虑应用于治疗PMS.第三代孕激素屈螺酮的出现让OCP治疗PMC出现曙光,研究表明含屈螺酮的OCP可以显著改善PMS症状,包括躯体、精神、行为症状,其效果优于其他OCP,且缩短OCP无激素间隔可能效果更好.

  20. Burden of menstrual symptoms in Japanese women – an analysis of medical care-seeking behavior from a survey-based study

    Directory of Open Access Journals (Sweden)

    Tanaka E

    2013-12-01

    , endometriosis, and premenstrual syndrome were the most commonly self-reported diagnoses, and oral contraceptives were frequently prescribed at gynecologist visits. Nonvisit group subjects felt that gynecologist consultations were unnecessary or felt resistant to them. Daily life was significantly improved after medical treatment from a gynecologist visit with associated economic savings, whilst the nonvisit group had no change after taking over-the-counter drugs to relieve their menstrual symptoms. Conclusion: The present study results indicate that Japanese women who were suffering from menstrual symptoms could benefit from visiting a gynecologist for easing their symptoms, hence improving their daily life. Keywords: menstrual symptoms, burden, outpatient, care-seeking, MDQ score, patient reported outcome

  1. with respiratory symptoms in Lilongwe

    African Journals Online (AJOL)

    Audit of outpatient department management of patients with respiratory symptoms ... verbal reports of main symptoms did not match with those recorded on OPD notes. .... palpitations, rheumatism, tonsillitis, general body pains, COAD, difficulty ...

  2. Celiac Disease: Symptoms, Diagnosis & Treatment

    Science.gov (United States)

    ... of this page please turn JavaScript on. Feature: Celiac Disease Symptoms, Diagnosis & Treatment Past Issues / Spring 2015 Table ... Contents What are some of the symptoms of celiac disease? Some people with celiac disease may not feel ...

  3. TBI Symptoms, Diagnosis, Treatment, Prevention

    Science.gov (United States)

    ... Past Issues Cover Story: Traumatic Brain Injury TBI Symptoms, Diagnosis, Treatment, Prevention Past Issues / Fall 2008 Table of ... turn Javascript on. Photo courtesy of ABC News Symptoms Mild: Person may remain conscious or be briefly ...

  4. Heart Disease: Symptoms, Diagnosis, Treatment

    Science.gov (United States)

    ... Past Issues Cover Story Heart Health Heart Disease: Symptoms, Diagnosis, Treatment Past Issues / Winter 2009 Table of Contents ... to view a larger version of the image Symptoms It is very important to learn the signs ...

  5. Colorectal Cancer: Symptoms, Diagnosis, Treatment

    Science.gov (United States)

    ... Past Issues Special Section: Colorectal Cancer Colorectal Cancer: Symptoms, Diagnosis and Treatment Past Issues / Spring 2009 Table of ... version of this page please turn Javascript on. Symptoms Check with your healthcare provider if you have ...

  6. Symptom attribution and symptom reporting in Australian Gulf War veterans.

    Science.gov (United States)

    Wright, Breanna K; McFarlane, Alexander C; Clarke, David M; Sim, Malcolm R; Kelsall, Helen L

    2015-12-01

    To better understand the consistent elevated symptom reporting by Gulf War veterans; we compared Australian Gulf War veterans and military-comparison group on symptom attributional styles and the relationship with total number and grouping of somatic and psychological symptoms. Postal questionnaires were completed by Australian Gulf War veterans (n=697) and military-comparison group (n=659) in 2000-2002 and 2011-2012. Data were collected on deployments, military-psychological stressors, symptom reporting, symptom factors and attributional style (normalising, psychologising, somatising, mixed-attribution). Gulf War veterans did not differ in attributional style from comparison group (p>0.05); normalising was the predominant style. Groups were combined for analyses. Psychologisers reported the highest overall symptoms (mean(M)=10.95, standard deviation(SD)=9.15), the most psychophysiological (M=1.71, SD=2.82), cognitive (M=5.79, SD=5.09) and arthro-neuromuscular symptoms (M=1.53, SD=1.73). Psychologisers and somatisers reported significantly more symptoms across overall symptoms, all three symptom factors and psychological distress than normalisers. Normalisers consistently reported fewest overall symptoms (M=2.85, SD=4.49), psychophysiological (M=0.40, SD=0.98), cognitive (M=1.14, SD=2.22), and arthro-neuromuscular symptoms (M=0.72, SD=1.31). Persistent symptoms, rather than remitted, between baseline and follow-up were associated with increased rates of psychologising and mixed-attribution compared with normalising. For incident symptoms a similar pattern was observed, some symptoms also showed increased rates of somatising. In veterans, psychologising was associated with higher symptom reporting, whilst somatisers and mixed-attribution also demonstrated higher reporting than normalisers. Symptom persistence and incidence were associated with symptom attribution. The findings indicate that attributional style is associated with patterns of symptom reporting and

  7. Symptom Clusters among Young Adolescents.

    Science.gov (United States)

    Knishkowsky, Barry; And Others

    1995-01-01

    Examines recurrent psychosomatic symptoms and symptom clusters among Israeli school children (n=259). Results of a questionnaire that asked about the frequency of 8 psychosomatic and 8 organic complaints indicated that girls had a higher prevalence than boys for 8 of the symptoms, and that abdominal pain and headache were each reported as an…

  8. Gender, Anxiety, and Depressive Symptoms

    Science.gov (United States)

    Chaplin, Tara M.; Gillham, Jane E.; Seligman, Martin E. P.

    2009-01-01

    Does anxiety lead to depression more for girls than for boys? This study prospectively examines gender differences in the relationship between anxiety and depressive symptoms in early adolescence. One hundred thirteen 11- to 14-year-old middle school students complete questionnaires assessing depressive symptoms and three dimensions of anxiety (worry and oversensitivity, social concerns and concentration, and physiological anxiety) as well as total anxiety symptoms at an initial assessment and 1 year later. Total anxiety and worry and oversensitivity symptoms are found to predict later depressive symptoms more strongly for girls than for boys. There is a similar pattern of results for social concerns and concentration symptoms, although this does not reach statistical significance. Physiological anxiety predicts later depressive symptoms for both boys and girls. These findings highlight the importance of anxiety for the development of depression in adolescence, particularly worry and oversensitivity among girls. PMID:19756209

  9. 绝经前卵巢上皮性癌预后因素分析%Clinical analysis about prognostic factors of the ovarian epithelial cell in cancer premenstrual woman

    Institute of Scientific and Technical Information of China (English)

    林丽红; 郭玉

    2012-01-01

    Objective To investigate prognostic factors of the premenstrual woman with ovarian epithelial cell cancer. Methods From January 2000 to January 2007, the data on 163 cases of patients were collected,and the factors which affected prognosis were retrospectively analyzed. Based on five years of follow-up, the survival rate was compared between layer factors with chi-square test, life method was used in calculation of survival, Kaplan-meier, Log-rank and COX multi-factor mode analytic method was respectively adopted to analyze variables, survival differences and multi-factors analysis. Results The 2-year survival rate was 79.07%, with a 46.01% 5-year survival rate; the cytology grade, residual tumor size and the method of surgery were prognostic factors (P < 0.01) according to the Cox-model multifactor results; based on the COX model multi-factor analysis, cytology classification, residual focal size, the operation method were the independent factors affecting the prognosis (P < 0.01); A statistical significance was found about the 5-year survival rate between every group under a different layer factors by a single factor Logistic regression analysis (P < 0.01). Conclusion The research data shows earlier staging, higher cell differentiation, fewer residual focal size, more optimistic prognosis for the premenstrual epithelial ovarian carcinoma.%目的 探讨影响绝经前卵巢上皮性癌患者生存预后的相关因素.方法 回顾性分析2000年1月~2007年1月共163例绝经前卵巢上皮性癌患者临床资料,评估预后因素.随访时间为5年,各分层因素间生存率比较采用χ2检验,寿命法计算生存率,Kaplan-meier法分析变量,Log-rank法检验生存差异,COX多因素模型进行多因素分析.结果绝经前卵巢上皮性癌患者2年生存率为79.75%,5年生存率为46.01%.单因素逐步COX模型分析与分层因素间生存率比较结果显示:临床分期、病理类型、细胞学分级、残留灶大小、手术方式是

  10. Efficacy and safety of a combined oral contraceptive containing drospirenone 3 mg and ethinylestradiol 20 μg in the treatment of premenstrual dysphoric disorder:a randomized, double blind placebo-controlled study%屈螺酮炔雌醇片治疗经前期情绪障碍的疗效及安全性

    Institute of Scientific and Technical Information of China (English)

    付艺; 张晋碚; 宓为峰; 李玲芝; 张鸿燕; 王嘉; 程文俊; 孙丽洲; 李凌江; 谢世平

    2014-01-01

    目的:评价屈螺酮炔雌醇片(其他名称:优思悦,简称:YAZ)治疗经前期情绪障碍(PMDD)的疗效及安全性。方法采用为期3个周期(每个周期28 d)随机、双盲、安慰剂对照、多中心的临床研究方法,全国共有17个中心参与本研究,首例入组时间为2009年1月13日,末位受试者末次访视时间为2011年1月7日。按1:1的比例将187例PMDD患者随机纳入YAZ组(93例)或安慰剂组(94例)。主要疗效指标为问题严重程度每天记录量表(DRSP)前21项评分治疗前后的差值,并评价安全性。结果 YAZ组、安慰剂组患者治疗前后DRSP量表前21项评分的差值中位数分别为-28.7分(范围是-82.5~2.3分)、-23.7分(范围是-86.0~11.8分),YAZ组优于安慰剂组,但两组比较,差异无统计学意义(P>0.05)。在本研究的治疗期间,未出现死亡或严重的不良事件;YAZ的主要不良事件为月经间期出血(13%,12/93)、月经过多(9%,8/93)、恶心(5%,5/93)、皮疹(4%,4/93)。结论 YAZ对PMDD患者的症状有改善作用,有效性略高于安慰剂;不良反应轻微,安全性好。%Objective To compare the efficacy and safety of a new low-dose oral contraceptive pill (YAZ) containing drospirenone 3 mg and ethinylestradiol 20 μg with placebo in reducing symptoms of premenstrual dysphoric disorder (PMDD). Methods This multicenter, double-blind, randomized clinical trial consisted of 2 run-in and 3 treatment cycles (84 days) with daily symptom charting; 187 women with symptoms of PMDD were randomized to either placebo group (n=94) or YAZ group (n=93), and assessed with daily record of severity of problems scale (DRSP) and clinical global impressions scale (CGI) before, during and after the treatments. Hormones were administered for 24 days, followed by 4 days of inactive pills. Results Compared with baseline level of DRSP, both groups got improvement after

  11. Vasomotor symptoms and metabolic syndrome.

    Science.gov (United States)

    Tuomikoski, Pauliina; Savolainen-Peltonen, Hanna

    2017-03-01

    A vast majority of menopausal women suffer from vasomotor symptoms, such as hot flushes and night sweats, the mean duration of which may be up to 7-10 years. In addition to a decreased quality of life, vasomotor symptoms may have an impact on overall health. Vasomotor symptoms are associated with overactivity of the sympathetic nervous system, and sympathetic overdrive in turn is associated with metabolic syndrome, which is a known risk factor for cardiovascular disease. Menopausal hot flushes have a complex relationship to different features of the metabolic syndrome and not all data point towards an association between vasomotor symptoms and metabolic syndrome. Thus, it is still unclear whether vasomotor symptoms are an independent risk factor for metabolic syndrome. Research in this area is constantly evolving and we present here the most recent data on the possible association between menopausal vasomotor symptoms and the metabolic syndrome.

  12. Symptom,sign and syndrome

    Institute of Scientific and Technical Information of China (English)

    1995-01-01

    950416 A clinicopathological study on mental andnervous symptoms in uremia.CUI Xiaoying(崔晓英),et al.Dept Intern Med,202nd Hosp,PLA,Shenyang110003.Chin J Neurol & Psychiat 1995;28(1):26-28.Mental and nervous symptoms,brainstem auditoryevoked potential(BAEP),brain computed tomography(CT) scans and pathological changes were studied in34 uremic patients.It was shown that mental depres-sion was the most common symptom.The latency of

  13. Persistent Negative Symptoms in Schizophrenia: An Overview

    OpenAIRE

    Buchanan, Robert W.

    2006-01-01

    Persistent negative symptoms represent an alternative approach for assessing negative symptoms in the context of clinical trials. Persistent negative symptoms are designed to capture those symptoms that lead to functional impairment but are currently understudied and for which there are no currently available effective treatments. Persistent negative symptoms differ from the 2 most commonly used approaches: primary, enduring negative symptoms or deficit symptoms and negative symptoms broadly ...

  14. Depressive symptoms in neurodegenerative diseases.

    Science.gov (United States)

    Baquero, Miquel; Martín, Nuria

    2015-08-16

    Depressive symptoms are very common in chronic conditions. This is true so for neurodegenerative diseases. A number of patients with cognitive decline and dementia due to Alzheimer's disease and related conditions like Parkinson's disease, Lewy body disease, vascular dementia, frontotemporal degeneration amongst other entities, experience depressive symptoms in greater or lesser grade at some point during the course of the illness. Depressive symptoms have a particular significance in neurological disorders, specially in neurodegenerative diseases, because brain, mind, behavior and mood relationship. A number of patients may develop depressive symptoms in early stages of the neurologic disease, occurring without clear presence of cognitive decline with only mild cognitive deterioration. Classically, depression constitutes a reliable diagnostic challenge in this setting. However, actually we can recognize and evaluate depressive, cognitive or motor symptoms of neurodegenerative disease in order to establish their clinical significance and to plan some therapeutic strategies. Depressive symptoms can appear also lately, when the neurodegenerative disease is fully developed. The presence of depression and other neuropsychiatric symptoms have a negative impact on the quality-of-life of patients and caregivers. Besides, patients with depressive symptoms also tend to further decrease function and reduce cognitive abilities and also uses to present more affected clinical status, compared with patients without depression. Depressive symptoms are treatable. Early detection of depressive symptoms is very important in patients with neurodegenerative disorders, in order to initiate the most adequate treatment. We review in this paper the main neurodegenerative diseases, focusing in depressive symptoms of each other entities and current recommendations of management and treatment.

  15. Neurobiological background of negative symptoms.

    Science.gov (United States)

    Galderisi, Silvana; Merlotti, Eleonora; Mucci, Armida

    2015-10-01

    Studies investigating neurobiological bases of negative symptoms of schizophrenia failed to provide consistent findings, possibly due to the heterogeneity of this psychopathological construct. We tried to review the findings published to date investigating neurobiological abnormalities after reducing the heterogeneity of the negative symptoms construct. The literature in electronic databases as well as citations and major articles are reviewed with respect to the phenomenology, pathology, genetics and neurobiology of schizophrenia. We searched PubMed with the keywords "negative symptoms," "deficit schizophrenia," "persistent negative symptoms," "neurotransmissions," "neuroimaging" and "genetic." Additional articles were identified by manually checking the reference lists of the relevant publications. Publications in English were considered, and unpublished studies, conference abstracts and poster presentations were not included. Structural and functional imaging studies addressed the issue of neurobiological background of negative symptoms from several perspectives (considering them as a unitary construct, focusing on primary and/or persistent negative symptoms and, more recently, clustering them into factors), but produced discrepant findings. The examined studies provided evidence suggesting that even primary and persistent negative symptoms include different psychopathological constructs, probably reflecting the dysfunction of different neurobiological substrates. Furthermore, they suggest that complex alterations in multiple neurotransmitter systems and genetic variants might influence the expression of negative symptoms in schizophrenia. On the whole, the reviewed findings, representing the distillation of a large body of disparate data, suggest that further deconstruction of negative symptomatology into more elementary components is needed to gain insight into underlying neurobiological mechanisms.

  16. Betahistine for symptoms of vertigo

    NARCIS (Netherlands)

    Murdin, Louisa; Hussain, Kiran; Schilder, Anne G M

    2016-01-01

    BACKGROUND: Vertigo is a symptom in which individuals experience a false sensation of movement. This type of dizziness is thought to originate in the inner ear labyrinth or its neural connections. It is a commonly experienced symptom and can cause significant problems with carrying out normal

  17. Menopause. How Exercise Mitigates Symptoms.

    Science.gov (United States)

    Hargarten, Kathleen M.

    1994-01-01

    During menopause and the climacteric, women experience many changes that can affect nearly every organ system and cause psychological symptoms. This article reviews the specific changes and explains how exercise can address each symptom; outlines a practical approach physicians can use to help menopausal patients improve their quality of life. (SM)

  18. Symptoms in Children After Chemotherapy

    Directory of Open Access Journals (Sweden)

    Sevcan Atay Turan

    2016-08-01

    Full Text Available Introduction: Identification of symptoms resulted from chemotherapy in children. Materials and Methods: In this study 46 children and adolescents who had chemotherapy in a pediatric oncology clinic of an oncology hospital were included. Sociodemographic questionnaire and Memorial Symptom Assessment Scale (10-18 years were used as data collection tool. Results: In this survey the mean age of children with cancer was 13.47±2.14 years and the majority of them (41.3% were monitored with non-Hodgkin’s lymphoma diagnosis. The most common symptoms in children who had chemotherapy in hospital were fatigue (76.1%, feeling nervous (69.6%, alopecia (65.2%, nausea (60.9% and feeling sad (60.9%, while the least common symptoms were swelling in the arms/legs (8.7% and problems in urination (6.5%. The most troublesome symptoms were dizziness (66.6%, difficulty in swallowing (64.3%, pain (47.8% and hair loss (43.4%. Conclusions: It was seen that the children still experience high prevalence of post-treatment symptoms, they had more intense psychological symptoms and physical symptoms caused more discomfort.

  19. Betahistine for symptoms of vertigo

    NARCIS (Netherlands)

    Murdin, Louisa; Hussain, Kiran; Schilder, Anne G M

    2016-01-01

    BACKGROUND: Vertigo is a symptom in which individuals experience a false sensation of movement. This type of dizziness is thought to originate in the inner ear labyrinth or its neural connections. It is a commonly experienced symptom and can cause significant problems with carrying out normal activi

  20. Turning symptoms into allies: utilization approaches with posttraumatic symptoms.

    Science.gov (United States)

    Phillips, M

    1993-01-01

    Adult patients with symptoms connected to the trauma of childhood sexual abuse often present in therapy with multiple symptoms and life difficulties and offer a challenge to even the most experienced clinician. In this paper, I describe my work with three such patients who were crippled in different ways by symptoms that had proved resistant to years of various therapeutic interventions. In every case, I accepted and utilized these symptoms as positive resources for successful and rapid change. Patients were then taught self-utilization approaches which allowed them to sustain and extend initial improvements. I conclude that the indirect utilization principle introduced by Milton Erickson provides an effective method to use in approaching some of the more persistent patterns of posttraumatic symptomatology related to childhood sexual abuse.

  1. Perimenstrual symptoms and symptoms at midlife in Puebla, Mexico.

    Science.gov (United States)

    Sievert, L L; Bertone-Johnson, E

    2013-02-01

    To examine perimenstrual symptoms in relation to hot flushes and depressive symptoms among 755 pre- and postmenopausal women aged 40-60 years drawn from a general population in Puebla, Mexico. Hot flushes and depressed mood during the past 2 weeks were queried, along with cramps and other symptoms experienced during or before menstruation. Relationships among perimenstrual symptoms were examined by factor analyses. Logistic regression was used to assess determinants of hot flushes and determinants of depressed mood at midlife. Fifty-four percent of the women reported abdominal cramping (cólicos) during menstruation; fewer reported irritability (8%) and depressed mood (9%). Gastrointestinal complaints were most frequently volunteered (12%), followed by breast tenderness (10%) and mid-back pain (9%). Emotional symptoms clustered separately from perimenstrual symptoms. In bivariate analyses, abdominal cramping and waist pain were associated with hot flushes at midlife (p <0.01) and remained significant determinants after controlling for potential confounders. Depressed mood with menstruation was associated with depressed mood at midlife (p <0.05). After controlling for education, socioeconomic status and parity, perimenstrual irritability and depressed mood raised the risk of midlife depressed mood, although significance was lost after adding current hot flushes and trouble sleeping. The relationship between abdominal cramps and hot flushes may be hormonal or sociocultural. The lack of association between depressed mood with menstruation and depressed mood at midlife after controlling for current hot flushes and trouble sleeping suggests that concurrent difficulties were more important than past history of depression in this population.

  2. Nivel de iones sérica y su relación con los síntomas del síndrome premenstrual en mujeres jóvenes

    Directory of Open Access Journals (Sweden)

    Larissa Almenara Silva dos Santos

    2013-12-01

    Full Text Available El objetivo del estudio fue evaluar el nivel de iones séricos y su relación con el síndrome premenstrual (PMS Los síntomas en las mujeres jóvenes. Método: Noventa y tres voluntarios fueron monitoreados durante tres meses. La evaluación del estado nutricional se basa en el índice de masa corporal. Tres "mapas de síntomas diarios" se utilizaron para investigar la frecuencia de los síntomas de SPM. La evaluación bioquímica se realizó en el primer mes de la fase lútea. Los niveles de sodio, de potasio, de calcio, de magnesio se determinaron por métodos colorimétricos. La concentración de hemoglobina y hematocrito se determinaron por métodos convencionales. Resultados: Los síntomas como la ansiedad (1,13, 0,81, 0,66, edema (0,99, 0,51, 0,22 e, depresión (0,58, 0,36, 0,20 y la mastalgia (0,56; 0,35; 0,09 fueron los más evidentes en el ciclo menstrual de lútea y la fase folicular. Un pequeño número de voluntarios presentó hipocalemia (1,4%, hiponatremia (4,22% y la hipernatremia (7,04%. Sin embargo, el mayor número de los voluntarios presentó menor nivel de calcio (83,09%. La frecuencia de las mujeres anémicas fue alta (24%. Se encontraron asociaciones significativas (P < 0,05 entre el síntoma de ansiedad y sodio (r = 0,2630, y magnesio y la depresión (r = 0,2508 y náuseas (r = 2,882. Conclusiones: La anemia y la hipocalcemia es un problema nutricional importante. La regulación de la concentración sérica de calcio parece ser afectada en la fase lútea del ciclo menstrual y el sodio y los iones de magnesio influir en algunos (ansiedad y depresión psicológica y los síntomas gastrointestinales (náuseas y estreñimiento.

  3. Symptoms and Treatment of Depression

    Medline Plus

    Full Text Available ... for a few days. It is a serious illness that affects many people. Symptoms can vary, but ... fighting. NARRATOR : Depression is a real and complex illness that is not yet completely understood. We do ...

  4. Symptoms and Treatment of Depression

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    Full Text Available ... Funding Home Opportunities & Announcements Funding Strategy for Grants Application Process Managing Grants Clinical Research Training Labs at ... give up. Read more about depression on this Web page. If the symptoms fit, get help now. ...

  5. Symptoms and Treatment of Depression

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    Full Text Available ... Opportunities & Announcements Funding Strategy for Grants Application Process Managing Grants Clinical Research Training Labs at NIMH Labs ... Symptoms and Treatment of Depression February 1, 2010 People with depression discuss how they got help. & ...

  6. Symptoms and Treatment of Depression

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    Full Text Available ... a minute really to do anything that took deep concentration. I tried a journal and I tried ... give up. Read more about depression on this Web page. If the symptoms fit, get help now. ...

  7. Cradle Cap: Symptoms and Causes

    Science.gov (United States)

    Cradle cap Symptoms and causes By Mayo Clinic Staff Common signs of cradle cap include: Patchy scaling or thick crusts on the ... on the ears, eyelids, nose and groin. Cradle cap is common in newborns. It usually isn't ...

  8. Symptoms and Treatment of Depression

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    Full Text Available ... me to do anything for myself. NARRATOR : Depression is more than just a feeling of being down ... dumps or blue for a few days. It is a serious illness that affects many people. Symptoms ...

  9. Symptoms and Treatment of Depression

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    Full Text Available ... Us About Us Home About the Director Advisory Boards and Groups Strategic Plan Offices and Divisions Budget ... few days. It is a serious illness that affects many people. Symptoms can vary, but many depressed ...

  10. Symptoms and Treatment of Depression

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    Full Text Available ... 3 items) Institute Announcements (24 items) Symptoms and Treatment of Depression February 1, 2010 People with depression ... why it affects some people but not others. Treatments for depression do work. One type of effective ...

  11. Symptoms and Treatment of Depression

    Medline Plus

    Full Text Available ... a minute really to do anything that took deep concentration. I tried a journal and I tried ... give up. Read more about depression on this Web page. If the symptoms fit, get help now. ...

  12. Signs and Symptoms of Mumps

    Science.gov (United States)

    ... Serology Publications and Resources Multimedia MMWR Articles Outbreak Articles Related Links World Health Organization Medline Plus Signs & Symptoms of Mumps Language: English Español (Spanish) Recommend on Facebook Tweet Share Compartir ...

  13. Symptoms and Treatment of Depression

    Medline Plus

    Full Text Available ... 3 items) Institute Announcements (24 items) Symptoms and Treatment of Depression February 1, 2010 People with depression ... why it affects some people but not others. Treatments for depression do work. One type of effective ...

  14. Symptoms and Treatment of Depression

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    Full Text Available ... a serious illness that affects many people. Symptoms can vary, but many depressed people lose interest in ... lot of weight. NARRATOR : A person with depression can feel irritable and restless, and have sleep problems. ...

  15. Cranial Autonomic Symptoms in Migraine

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2009-11-01

    Full Text Available Cranial autonomic symptoms (CAS in patients with migraine and cluster headaches (CH were characterized and compared in a prospective study of consecutive patients attending a headache clinic at Taipei Veterans General Hospital, Taiwan.

  16. Understanding ADHD: Symptoms in Children

    Science.gov (United States)

    ... this page please turn JavaScript on. Feature: Understanding ADHD Symptoms In Children Past Issues / Spring 2014 Table ... hyperactivity, and impulsivity are the key behaviors of ADHD. It is normal for all children to be ...

  17. What Are the Symptoms of Pituitary Tumors?

    Science.gov (United States)

    ... Clinical Trials Resources and Publications What are the symptoms of pituitary tumors? Skip sharing on social media links Share this: Page Content Symptoms of Functioning Tumors The symptoms of functioning tumors ...

  18. What Are the Symptoms of Endometriosis?

    Science.gov (United States)

    ... the case. Hormone therapy such as estrogen or birth control pills, given to reduce menopausal symptoms, may cause these endometriosis symptoms to continue. Endometriosis-Related Pain Researchers know that pain is a primary symptom ...

  19. Alzheimer's Disease: Symptoms, Diagnosis and Treatment

    Science.gov (United States)

    ... page please turn Javascript on. Feature: Alzheimer's Disease Symptoms, Diagnosis and Treatment Past Issues / Fall 2010 Table of Contents Symptoms Scientists believe that changes in the brain may ...

  20. Diabetes Complications and Depressive Symptoms

    DEFF Research Database (Denmark)

    Deschênes, Sonya S; Burns, Rachel J; Pouwer, Frans

    2017-01-01

    the course of the follow-up period (β= 0.74, p diabetes complications and depressive symptoms and underscores the psychological burden of diabetes complications by prospectively demonstrating the increased risk and recurrence......OBJECTIVE: Prospective studies testing the potential impact of diabetes complications on depression are limited. The present study examined the longitudinal associations between diabetes complications and the risk and recurrence/persistence of depressive symptoms. METHODS: Data were from...... a prospective community cohort telephone survey of adults with diabetes (N= 1,314). Diabetes complications and depressive symptoms were assessed via self-report (Diabetes Complications Index and Patient Health Questionnaire-9, respectively) at baseline and annually for 5 years. Statistical models adjusted...

  1. [Symptoms and management of tetany].

    Science.gov (United States)

    Ito, Nobuaki; Fukumoto, Seiji

    2007-08-01

    Tetany is a series of symptoms characterized by painful muscle cramp that derives from enhanced neuromuscular excitability due to hypocalcemia, hypomagnesemia or alkalosis. In a broad sense, tetany includes associated sensory disturbance. Typical symptoms of tetany include carpopedal spasm, laryngospasm and generalized seizure. Chvostek and Trousseau signs are provocative tests for diagnosis of latent tetany. Many diseases including endocrine disorders like hypoparathyroidism and alkalosis by hyperventilation can cause tetany. Infusion of calcium or magnesium is effective as an acute therapy for tetany. However, subsequent diagnosis and treatment of underlining diseases are mandatory.

  2. Betahistine for symptoms of vertigo.

    Science.gov (United States)

    Murdin, Louisa; Hussain, Kiran; Schilder, Anne G M

    2016-06-21

    Vertigo is a symptom in which individuals experience a false sensation of movement. This type of dizziness is thought to originate in the inner ear labyrinth or its neural connections. It is a commonly experienced symptom and can cause significant problems with carrying out normal activities. Betahistine is a drug that may work by improving blood flow to the inner ear. This review examines whether betahistine is more effective than a placebo at treating symptoms of vertigo from different causes. To assess the effects of betahistine in patients with symptoms of vertigo from different causes. The Cochrane ENT Information Specialist searched the Cochrane ENT Trials Register; Central Register of Controlled Trials (CENTRAL 2015, Issue 8); PubMed; EMBASE; CINAHL; Web of Science; ClinicalTrials.gov; ICTRP and additional sources for published and unpublished trials. We also contacted manufacturers and researchers in the field. The date of the search was 21 September 2015. We included randomised controlled trials of betahistine versus placebo in patients of any age with vertigo from any neurotological diagnosis in any settings. We used the standard methodological procedures expected by Cochrane. Our primary outcome was the proportion of patients with reduction in vertigo symptoms (considering together the intensity, frequency and duration those symptoms). We included 17 studies, with a total of 1025 participants; 12 studies were published (567 patients) and five were unpublished (458 patients). Sixteen studies including 953 people compared betahistine with placebo. All studies with analysable data lasted three months or less. The majority were at high risk of bias, but in some the risk of bias was unclear. One study, at high risk of bias, included 72 people with benign paroxysmal positional vertigo (BPPV) and compared betahistine with placebo; all patients also had particle repositioning manoeuvres. The studies varied considerably in terms of types of participants, their

  3. Symptoms

    Science.gov (United States)

    ... diabetes. Shopdiabetes.org: Your Stress-Free System for Family Dinners! - 2017-03-book-oclock-scramble.html Shopdiabetes.org Your Stress-Free System for Family Dinners! A year of delicious meals to help prevent ...

  4. Massage therapy for fibromyalgia symptoms.

    Science.gov (United States)

    Kalichman, Leonid

    2010-07-01

    Massage therapy is widely used by patients with fibromyalgia seeking symptom relief. We performed a review of all available studies with an emphasis on randomized controlled trials to determine whether massage therapy can be a viable treatment of fibromyalgia symptoms. Extensive narrative review. PubMed, PsychInfo, CINAHL, PEDro, ISI Web of Science, and Google Scholar databases (inception-December 2009) were searched for the key words "massage", "massotherapy", "self-massage", "soft tissue manipulation", "soft tissue mobilization", "complementary medicine", "fibromyalgia" "fibrositis", and "myofascial pain". No language restrictions were imposed. The reference lists of all articles retrieved in full were also searched. The effects of massage on fibromyalgia symptoms have been examined in two single-arm studies and six randomized controlled trials. All reviewed studies showed short-term benefits of massage, and only one single-arm study demonstrated long-term benefits. All reviewed studies had methodological problems. The existing literature provides modest support for use of massage therapy in treating fibromyalgia. Additional rigorous research is needed in order to establish massage therapy as a safe and effective intervention for fibromyalgia. In massage therapy of fibromyalgia, we suggest that massage will be painless, its intensity should be increased gradually from session to session, in accordance with patient's symptoms; and the sessions should be performed at least 1-2 times a week.

  5. Perfectionism, Shame, and Depressive Symptoms

    Science.gov (United States)

    Ashby, Jeffrey S.; Rice, Kenneth G.; Martin, James L.

    2006-01-01

    The authors examined the relationship between depression, maladaptive perfectionism, and shame. Regression analyses were used to replicate a model in which maladaptive perfectionism was negatively associated with self-esteem and positively associated with symptoms of depression, with self-esteem mediating the effects of maladaptive perfectionism…

  6. Symptoms and Treatment of Depression

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    Full Text Available ... items) Alzheimer’s Disease (2 items) Coping with Traumatic Events (3 items) Institute Announcements (24 items) More Multimedia ... items) Alzheimer’s Disease (2 items) Coping with Traumatic Events (3 items) Institute Announcements (24 items) Symptoms and ...

  7. Symptoms and Treatment of Depression

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    Full Text Available ... to recovery. Depression treatment can take time to work, so don't give up. Read more about depression on this Web page. If the symptoms fit, get help now. ... of Scientific Meetings Information about NIMH RePORTER : Research Portfolio Online ...

  8. Symptoms and Treatment of Depression

    Medline Plus

    Full Text Available ... 3 items) Institute Announcements (24 items) Symptoms and Treatment of Depression February 1, 2010 People with depression discuss how ... why it affects some people but not others. Treatments for depression do work. One type of effective psychotherapy is ...

  9. Symptoms and Treatment of Depression

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    Full Text Available ... the road to recovery. Depression treatment can take time to work, so don't give up. Read more about depression on this Web page. If the symptoms fit, get help now. Share More Video and Audio about Depression Contact ...

  10. Symptoms and Treatment of Depression

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    Full Text Available ... depression on this Web page. If the symptoms fit, get help now. Share More Video and Audio ... Office 301-443-4536 NIMHpress@nih.gov Press Resources Mental Health Information Summaries of Scientific ... Contact Us Staff Directories Privacy Notice Policies ...

  11. FRIEDRICH TRENDELENBURG AND TRENDELENBURG'S SYMPTOM

    Directory of Open Access Journals (Sweden)

    Z. K. Bashurov

    2010-01-01

    Full Text Available In 1895 German surgeon Frederic Trendelenburg has described the symptom of failure of gluteus medius and gluteus minimus muscles at congenital hip dislocation which named after him today. There is full translation of this article, the picture and the Trendelenburg's portrait cited in this report.

  12. Functional bowel symptoms and diet.

    Science.gov (United States)

    Gibson, P R; Barrett, J S; Muir, J G

    2013-10-01

    It is well recognised that ingestion of food is a trigger for functional bowel symptoms, particularly those associated with irritable bowel syndrome (IBS). Patients often use manipulation of diet as a means of controlling symptoms. Despite description of multiple dietary methods, few have scientific backing or quality evidence of efficacy. One approach is to define how specific food components influence the pathophysiology of IBS and then rationally design dietary approaches. For example, short-chain poorly absorbed carbohydrates (fermentable oligo-, di- and mono-saccharides and polyols (FODMAP)) cause luminal distension, which is a major stimulus for the development of symptoms in patients with visceral hypersensitivity. By determining food content of FODMAP, a diet in which foods low in FODMAP are favoured over those high in FODMAP can be designed. Observational, comparative and randomised controlled treatment and rechallenge studies have shown that such an approach is efficacious in the majority of patients with IBS. The low FODMAP diet is now the primary dietary therapy for such patients. Similar approaches can be applied to other food components, including proteins (such as gluten), fats and natural bioactive food chemicals. Such approaches have suggestions of efficacy, but the evidence base remains underdeveloped. An additional and important consideration for any dietary therapy is its nutritional adequacy and potential adverse health effects. Dietary manipulation is now a key management strategy in patients with functional bowel symptoms. Future well-designed interventional studies will lead to refinement of dietary approaches taken and to a better understanding of their long-term safety.

  13. The Signaling Theory of Symptoms

    Directory of Open Access Journals (Sweden)

    Leander Steinkopf

    2015-08-01

    Full Text Available Placebo research shows that the subjective quality of care and social support, as well as the patients’ expectations of treatment, influence therapeutic outcomes. However, this phenomenon, known as the placebo effect, does not usually cure the disease, but rather can provide symptomatic relief: It may soothe symptoms such as pain, swelling, or nausea that constitute part of an immune response. The function of this mechanism remains unclear. This article puts forward the Signaling Theory of Symptoms (STS as a possible explanation. According to STS, discernible aspects of an immune response, such as pain, swelling, or nausea, not only serve a defensive and healing function but also a signaling function: symptoms signal the need for care and treatment to potential helpers. Once help and treatment are granted, the signaling function is fulfilled and the symptoms diminish. This mechanism may have been a significant advantage in preindustrial environments, when sufferers depended on extensive social support and personal treatment. Nowadays, from the point of view of modern materialist medicine, the mobilization of social support no longer seems so crucial, and thus the placebo effect has been assigned a somewhat mysterious quality.

  14. Perfectionism, Shame, and Depressive Symptoms

    Science.gov (United States)

    Ashby, Jeffrey S.; Rice, Kenneth G.; Martin, James L.

    2006-01-01

    The authors examined the relationship between depression, maladaptive perfectionism, and shame. Regression analyses were used to replicate a model in which maladaptive perfectionism was negatively associated with self-esteem and positively associated with symptoms of depression, with self-esteem mediating the effects of maladaptive perfectionism…

  15. Symptom,sign and syndrome

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    2010381 Clinical and electrophysiological characteristics of Lambert-Eaton myasthenic syndrome:retrospective study in forty-five patients. GUAN Yuzhou(管宇宙),et al. Dept Neurol,PUMC & CAMS,Bejing 100730. Chin J Neurol 2010;331-334. Objective To analyze the symptoms and signs in forty-five Lambert-Eaton myasthenia syndrome (LEMS)patients

  16. Symptoms as the main problem

    DEFF Research Database (Denmark)

    Rosendal, Marianne; Carlsen, Anders Helles; Rask, Mette Troellund

    2016-01-01

    Dette studie undersøger tilfredsheden hos patienter, der blev afsluttet i almen praksis uden specifik diagnose, dvs. hvor lægen efter afsluttet konsultation kun kunne anføre "symptom" eller "problem" som slutdiagnose. Det drejer sig om ca. 1/3 af alle helbredsrelaterede konsultationer i almen....... Tidligere undersøgelser af patienter med medicinsk uforklarede symptomer (MUS) eller funktionelle lidelser har ligeledes vist utilfredshed blandt patienterne, men denne undersøgelse peger nu på, at utilfredsheden også findes hos den store gruppe af patienter, der henvender sig med almindelige symptomer. Da...... håndtering af patienter med symptomer såvel i tidlig fase som ved langvarige tilstande er en kerneopgave for almen praksis, tyder patienternes tilbagemelding på, at der er behov for øget fokus på dette område i forskning, undervisning og den kliniske hverdag. Undersøgelsen bygger på spørgeskemaoplysninger...

  17. Symptom monitoring in treatment of cancer patients

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Objective To examine self-reported symptoms by the patients receiving cancer therapy, and find out the symptoms that should be coped with and managed during the treatment. Methods A pilot study was conducted on self-reported symptoms on 185 patients receiving chemotherapy and/or radiotherapy for different cancers. The Therapy-Related Symptoms Checklist (TRSC) was used. Results Severe symptoms on the TRSC subscales: loss of appetite, feeling sluggish, weight loss, nausea and hair loss, were reported by the p...

  18. Clinical symptoms and symptom signatures of Alzheimer's disease subgroups.

    Science.gov (United States)

    Iqbal, Khalid; Flory, Michael; Soininen, Hilkka

    2013-01-01

    Alzheimer's disease (AD) is a multifactorial disorder that involves several different mechanisms. Over 99% of AD patients suffer from the sporadic form of the disease. Based on cerebrospinal fluid (CSF) levels of amyloid-β (Aβ)(1-42), total tau, and ubiquitin--the markers associated with the histopathological hallmarks of the disease (Aβ plaques and abnormally hyperphosphorylated neurofibrillary tangles)--previous studies identified five subgroups of AD. Here we report the potential diagnostic predictive value of hallucination, hypokinesia, paranoia, rigidity, and tremors in aged individuals for AD and differences in the prevalence of these symptoms in the CSF marker-based subgroups of the disease. Analysis of 196 clinically diagnosed AD or Alzheimer with Lewy body, and 75 non-AD neurological and non-neurological control cases, all from a single center, showed that the presence of hallucination, hypokinesia, paranoia, rigidity, or tremors individually, or the presence of any of these, could diagnose AD with sensitivities and specificities of 14% and 99%; 30% and 99%; 15% and 99%; 16% and 100%; 16% and 96%; and 47% and 92%, respectively. The pattern of the prevalence of the above symptoms varied from AD subgroup to subgroup. Presence of any of these symptoms, as well as presence of each individual symptom except tremors, significantly differentiated AD subgroups from the predominantly control cluster. These findings encourage the exploration of hallucination, hypokinesia, paranoia, rigidity, and tremors in identifying various subgroups of AD for stratification of patients for clinical trials to develop therapeutic drugs. This study is for the special issue of the Journal of Alzheimer's Disease honoring Inge Grundke-Iqbal who made several seminal contributions in AD research.

  19. Poverty and adolescent depressive symptoms.

    Science.gov (United States)

    Butler, Amy C

    2014-01-01

    Longitudinal data on non-Hispanic White children from the Panel Study of Income Dynamics (N = 1,056) were used to examine whether the relationship between poverty (early childhood poverty, poverty persistence, and current poverty) and adolescent depressive symptoms (measured by the Children's Depression Inventory and the Internalizing Index) can be explained by the mother's own childhood depression and family characteristics measured during the child's first year of life. Associations between poverty and depressive symptoms among adolescents were explained by mother's childhood depression and whether the adolescent had lived with both parents during the first year of life. The findings highlight the need for appropriate treatment of childhood depression so as to reduce the adverse consequences in adulthood and for the next generation.

  20. Symptoms of menopause: hot flushes.

    Science.gov (United States)

    Santoro, Nanette

    2008-09-01

    Vasomotor symptoms (VMSs) are highly prevalent during the peri- and early postmenopause. They constitute a major driver for patient self-referral for medical care. Although most women will experience an abatement of their VMS by 5 years after their final menses, women with early or surgical menopause may have worse or more persistent symptoms, and up to 16% of naturally menopausal women continue to experience VMS well after their menopause is past. Although estrogen is the most effective known therapy, it is neither appropriate nor desirable for every symptomatic woman, and nonhormonal treatments such as gabapentin, selective serotonin reuptake inhibitors/selective norepinephrine reuptake inhibitors drugs, and the antihypertensives clonidine and alphamethyldopa may be helpful for some women. There is mounting evidence to support the ineffectiveness of many proposed complementary and alternative modalities. This review will highlight the natural history of VMS and the current medical evidence supporting various treatments.

  1. [Pain, from symptom to syndrome].

    Science.gov (United States)

    Piano, Virginie

    2017-05-01

    Acute pain is a symptom enabling us to implement a response when faced with an attack. Chronic pain is complex and multifactorial. The care of the patient by a multidisciplinary team comprises the diagnosis of the pain and the putting in place of a treatment for each of its components. This includes physical reconditioning, adaptation strategies and work on the psychological elements relating to the representation of the pain. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  2. Cholecystic fistula with atypical symptoms

    DEFF Research Database (Denmark)

    Bang, U.C.; Hasbak, P.; From, G.

    2008-01-01

    We report a patient with spontaneous cholecystocolonis fistula secondary to cholelithiasis. A 93 year-old woman was admitted because of weight loss, diarrhoea and upper abdominal pain. Ultrasound examination revealed air in the biliary tract and cholescientigraphy revealed a fistula between the g...... the gallbladder and right colon. Using endoscopic retrograde cholangiopancreatography a calculus was extracted from the bile duct and the symptoms disappeared Udgivelsesdato: 2008/1/14...

  3. [Neuropsychiatric symptoms in dementia syndrome].

    Science.gov (United States)

    Artaso Irigoyen, B; Goñi Sarriés, A; Gómez Martínez, A R

    The aim of this study was to describe the neuropsychiatric disorders that present in dementia and the differences they show at each stage as the disease progresses. The study involved a total of 175 patients from a psychogeriatric clinic who had been diagnosed as suffering from dementia at distinct stages of the disease: 66 had mild dementia, 56 were with moderate dementia and 53 were suffering from severe dementia. The following instruments were used to collect both socio demographic and clinical data: the Spanish version of the Mini Mental State Examination (miniexamen cognitivo: MEC) for cognitive impairment, the Barthel index for functional deterioration and the neuropsychiatric inventory (NPI) for the non cognitive symptoms. There were no significant differences in the NPI according to the degree of cognitive impairment and the most frequently seen symptoms were anomalous motor activity, apathy and irritability; the neuropsychiatric disorder that was least often present was euphoria. The presence of disinhibition, irritability, depression, hallucinations and anomalous motor activity varied significantly in the different phases of dementia. Thus, disinhibition, irritability and depression were more frequent in the initial stages of the disease whereas hallucinations and anomalous motor activity were seen more often when the cognitive impairment was severe. Neuropsychiatric disorders appear throughout the whole course of dementia and symptoms vary according to the stage of the disease.

  4. Mindfulness Is Associated with Fewer PTSD Symptoms, Depressive Symptoms, Physical Symptoms, and Alcohol Problems in Urban Firefighters

    Science.gov (United States)

    Smith, Bruce W.; Ortiz, J. Alexis; Steffen, Laurie E.; Tooley, Erin M.; Wiggins, Kathryn T.; Yeater, Elizabeth A.; Montoya, John D.; Bernard, Michael L.

    2011-01-01

    Objective: This study investigated the association between mindfulness, other resilience resources, and several measures of health in 124 urban firefighters. Method: Participants completed health measures of posttraumatic stress disorder (PTSD) symptoms, depressive symptoms, physical symptoms, and alcohol problems and measures of resilience…

  5. What Are the Symptoms of Pelvic Pain?

    Science.gov (United States)

    ... Resources and Publications What are the symptoms of pelvic pain? Skip sharing on social media links Share this: Page Content The symptoms of pelvic pain vary from woman to woman. Pelvic pain can ...

  6. What Are the Symptoms of Menopause?

    Science.gov (United States)

    ... Resources and Publications What are the symptoms of menopause? Skip sharing on social media links Share this: ... longer than a week. A common symptom of menopause is the appearance of hot flashes (sometimes called ...

  7. HIV / AIDS: Symptoms, Diagnosis, Prevention and Treatment

    Science.gov (United States)

    Skip Navigation Bar Home Current Issue Past Issues HIV / AIDS HIV / AIDS: Symptoms , Diagnosis, Prevention and Treatment Past Issues / ... Most people who have become recently infected with HIV will not have any symptoms. They may, however, ...

  8. 10 Early Signs and Symptoms of Alzheimer's

    Science.gov (United States)

    ... be a symptom of Alzheimer's or another dementia . Alzheimer's is a brain disease that causes a slow decline in memory, thinking and reasoning skills. There are 10 warning signs and symptoms. Every individual may experience one or more of ...

  9. Restless Legs Syndrome -- Causes and Symptoms

    Science.gov (United States)

    ... Overview & Facts Causes & Symptoms Self-Tests & Diagnosis Treatment Restless Legs Syndrome - Causes & Symptoms Causes What causes of restless legs syndrome varies from person to person. In some cases ...

  10. Haemophilus influenzae Disease (Including Hib) Symptoms

    Science.gov (United States)

    ... Search The CDC Cancel Submit Search The CDC Haemophilus influenzae Disease (Including Hib) Note: Javascript is disabled or ... and Symptoms Recommend on Facebook Tweet Share Compartir Haemophilus influenzae , including Hib, disease causes different symptoms depending on ...

  11. Food Allergies: Symptoms, Diagnosis, Prevention and Treatment

    Science.gov (United States)

    ... of this page please turn Javascript on. Feature: Food Allergies Food Allergies: Symptoms, Diagnosis, Prevention and Treatment Past Issues / ... available treatments only ease the symptoms. Preventing a food allergy reaction There are no drugs or treatments ...

  12. Glaucoma: Symptoms, Diagnosis, Treatment and Latest Research

    Science.gov (United States)

    ... page please turn Javascript on. Feature: Glaucoma Glaucoma: Symptoms, Diagnosis, Treatment and Latest Research Past Issues / Fall 2009 Table of Contents Symptoms and Diagnosis Glaucoma can develop in one or ...

  13. Symptoms Before Sudden Arrhythmic Death Syndrome

    DEFF Research Database (Denmark)

    Glinge, Charlotte; Jabbari, Reza; Risgaard, Bjarke

    2015-01-01

    INTRODUCTION: No studies in an unselected and nationwide setting have characterized the symptoms and medical history of patients with sudden arrhythmic death syndrome (SADS). The aim of this study was to identify and describe the symptoms and medical history of patients before the presentation....... The National Patient Registry was utilized to obtain information on all in- and outpatient activity in Danish hospitals. All medical records from hospitals and general practitioners, including death certificates and autopsy reports were reviewed. Before death, 48 (35%) SADS patients had cardiac symptoms; among...... these, 30 (22%) had contacted the healthcare system. Antecedent symptoms (symptoms >24 hours before death) were present in 34 (25%) patients. Prodromal symptoms (symptoms ≤24 hours before death) were present in 23 (17%) patients. Cardiac symptoms included chest pain (n = 16, 12%), dyspnea (n = 18, 13...

  14. Signs and Symptoms of Untreated Lyme Disease

    Science.gov (United States)

    ... FAQ Health care providers Educational materials Signs and Symptoms of Untreated Lyme Disease Recommend on Facebook Tweet ... area where Lyme disease occurs . Early Signs and Symptoms (3 to 30 days after tick bite) Fever, ...

  15. Signs and Symptoms of Mood Disorders

    Science.gov (United States)

    ... Public Service Announcements Partnering with DBSA Signs and Symptoms of Mood Disorders Depression and bipolar disorder (also ... a Confidential Online Mood Disorder Screening Signs and symptoms of depression Prolonged sadness or unexplained crying spells ...

  16. Musculoskeletal System Symptoms in Goiter

    Directory of Open Access Journals (Sweden)

    Sevim Akin

    2013-04-01

    Full Text Available Aim: The aim of this study was to investigate the prevalence of musculoskeletal manifestations in patients with thyroid dysfunction. Methods: One hundred and twenty-three patients (100 female, 23 male who visited the nuclear medicine department for thyroid gland scintigraphy were included in our study. According to thyroid hormone levels, patients were allocated into five categories: hyperthyroidism, subclinical hyperthyroidism, euthyroid, subclinical hypothyroidism, and hypothyroidism. Before neurological and musculoskeletal examinations, a standardized symptom questionnaire was completed including questions about sensory symptoms, muscle weakness, restricted joint mobility, musculoskeletal pain. Neurological examination, range of motion of joints, effusion or swelling of joints was assessed. Diagnosis of osteoarthritis was done by the clinical and radiological characteristics. The diagnosis of FMS was made according to criteria of American College of Rheumatology. According to the World Health Organization (WHO, a T-score ≤ -2.5 was classified as osteoporosis, whereas a T-score between -2.5 and -1.0 was classified as osteopenia. Thyroid status was determined by serum TSH levels. Results: Eighty-one percent of the patients were female (100 and 19% were male (23. Mean age of female patients was 49.99±15.27 years (range 20-87 and mean age of male patients was 61.8±12.33 years (range 34-88. When divided according to thyroid status, 21.1% (n=26 had hyperthyroidism, 21.1% (n=26 had subclinical hyperthyroidism, 49.6% (n=61 were euthyroid, 4.9% (n=6 had subclinical hypothyroidism and 3.3% (n=4 were hypothyroid. None of 59% of patients had any musculoskeletal diagnosis. Osteoporosis was the most common problem, affecting 23.7% of patients Conclusion: The presence of musculoskeletal symptoms in patients with goiter should be considered and investigated. [Cukurova Med J 2013; 38(2.000: 261-269

  17. Predicting depressive symptoms in unemployed

    Directory of Open Access Journals (Sweden)

    Marić Zorica

    2005-01-01

    Full Text Available In this study we review recent research literature focused on relationship between unemployment and depression, and theories emphasizing the mechanisms by which unemployment may contribute to increased levels of depression. Our research investigated depressive symptomatology and its predictors among unemployed people (N = 453 varying in length of unemployment. Results showed that self - mastery, self - esteem, financial strain, gender, intensity of job - seek behavior and length on unemployment were significant predictors of depressive symptoms. Results are discussed in light of current theories of unemployment and mental health and recommendations are made for practice.

  18. Prediction of withdrawal symptoms during opioid detoxification

    NARCIS (Netherlands)

    Dijkstra, Boukje A G; Krabbe, Paul F M; De Jong, Cor A J; van der Staak, Cees P F

    2008-01-01

    OBJECTIVE: The severity of self-reported withdrawal symptoms varies during detoxification of opioid-dependent patients. The aim of this study is to identify subgroups of withdrawal symptoms within the detoxification trajectory and to predict the severity of withdrawal symptoms on the basis of

  19. Schmerz: Symptom, Folge, Behandlung bei Multipler Sklerose

    Directory of Open Access Journals (Sweden)

    Schmidegg S

    2006-01-01

    Full Text Available Schmerz ist ein viel häufigeres Symptom bei Patienten mit Multipler Sklerose als angenommen. In 5,5 % der Patienten ist Schmerz ein vorherrschendes Symptom, entweder alleine oder in Kombination mit anderen Symptomen, z. B. der Spastizität. Häufigste Symptome sind ein zentral neuropathischer Schmerz, die Allodynie und Hyperalgesie sowie Trigeminusneuralgien.

  20. [Non-motor symptoms of Parkinson's disease

    NARCIS (Netherlands)

    Weerkamp, N.J.; Nijhof, A.; Tissingh, G.

    2012-01-01

    Parkinson's disease has traditionally been viewed as a disease with only motor features. Nowadays, a wide variety of non-motor symptoms and signs are also recognised as being characteristic of the disease. Non-motor symptoms, most importantly autonomic dysfunction, neuropsychiatric symptoms and slee

  1. Symptom attributions in patients with colorectal cancer

    DEFF Research Database (Denmark)

    Jensen, Line Flytkjær; Hvidberg, Line; Pedersen, Anette Fischer

    2015-01-01

    Størstedelen af kolorektal cancere opdages gennem patienters symptomatiske henvendelse i almen praksis. Man ved dog ikke meget om, hvordan patienter selv oplever deres symptomer. Formålet med studiet var, at undersøge om symptom attributioner er associeret med hvilket symptom man oplevede før...

  2. Vegan diet alleviates fibromyalgia symptoms.

    Science.gov (United States)

    Kaartinen, K; Lammi, K; Hypen, M; Nenonen, M; Hanninen, O; Rauma, A L

    2000-01-01

    The effect of a strict, low-salt, uncooked vegan diet rich in lactobacteria on symptoms in 18 fibromyalgia patients during and after a 3-month intervention period in an open, non-randomized controlled study was evaluated. As control 15 patients continued their omnivorous diet. The groups did not differ significantly from each other in the beginning of the study in any other parameters except in pain and urine sodium. The results revealed significant improvements in Visual analogue scale of pain (VAS) (p=0.005), joint stiffness (p=0.001), quality of sleep (p=0.0001), Health assessment questionnaire (HAQ) (p=0.031), General health questionnaire (GHQ) (p=0.021), and a rheumatologist's own questionnaire (p=0.038). The majority of patients were overweight to some extent at the beginning of the study and shifting to a vegan food caused a significant reduction in body mass index (BMI) (p=0.0001). Total serum cholesterol showed a statistically significant lowering (p=0.003). Urine sodium dropped to 1/3 of the beginning values (p=0.0001) indicating good diet compliance. It can be concluded that vegan diet had beneficial effects on fibromyalgia symptoms at least in the short run.

  3. Eating disorder symptoms and parenting styles.

    Science.gov (United States)

    Haycraft, Emma; Blissett, Jackie

    2010-02-01

    This study aimed to examine associations between symptoms of eating disorders and parenting style, in a non-clinical sample. One hundred and five mothers completed self-report measures of eating disorder symptoms and parenting style. Higher levels of eating disorder symptoms were associated with more authoritarian and permissive parenting styles. Authoritative parenting was not significantly related to eating disorder symptoms. The findings demonstrate that eating disorder symptoms in non-clinical individuals are related to less adaptive parenting styles. These findings have potential implications for clinicians working with mothers with eating disorders.

  4. Symptom monitoring in treatment of cancer patients

    Institute of Scientific and Technical Information of China (English)

    Yao Wanxia; Lin Miao; Lü Ye; Yang Biao; Yao Cong; Liu Juan; Wang Wenru

    2008-01-01

    Objective To examine self-reported symptoms by the patients receiving cancer therapy, and find out the symptoms that should be coped with and managed during the treatment. Methods A pilot study was conducted on self-reported symptoms on 185 patients receiving chemotherapy and/or radiotherapy for different cancers. The Therapy-Related Symptoms Checklist (TRSC) was used. Results Severe symptoms on the TRSC subscales: loss of appetite,feeling sluggish, weight loss, nausea and hair loss, were reported by the patients. The frequently reported symptoms by those on chemotherapy were nausea, feeling sluggish, weight loss, vomiting, and taste change. The frequently reported symptoms by those on radiotherapy were feeling sluggish, weight loss, loss of appetite, difficult sleeping, and changing taste. The symptoms of loss of appetite, feeling sluggish, weight loss, hair loss, and nausea were both frequently reported by those on radiotherapy and those on chemotherapy. Conclusion Symptom monitoring may be facilitated by TRSC, based on the severity and frequency of reported symptoms, more patients and caregivers could know which symptoms should be preferential interventions.

  5. Music therapy for dementia symptoms.

    Science.gov (United States)

    Koger, S M; Brotons, M

    2000-01-01

    While music/music therapy does not represent a treatment of dementia, its use is based on a possible beneficial effect on symptoms including social, emotional and cognitive skills and for decreasing behavioral problems of individuals with dementias. Thus, there are clear implications for patients' and caregivers' quality of life. However, quantification and documentation of the evidence of this effect is necessary. Professional music therapists are accountable for providing efficient, beneficial treatment. Further, music therapists are responsible for assessing, designing and implementing music therapy treatments, monitoring client progress, and reformulating their practice according to data collected and new advancements in the field. If they wait until sufficient valid, empirical data on all aspects of a disability or music response are available before attempting to design a therapy session, they may well reach retirement age before even one client can be served. On the other hand, promulgating the efficacy of music therapy in general, or of specific music therapy techniques, in the absence of any substantiation other than intuition or tradition borders on professional recklessness. To gather and evaluate the evidence for the effectiveness of music therapy for dementia symptoms. All available sources of references were searched for randomised controlled trials of music therapy used as an intervention in dementia. The search terms included 'controlled trial or study, music*, therapy, dement*, Alzheimer*, cognitive impairment.' The reviewers assessed the methodological quality of the studies available for inclusion. The criteria used are presence and adequacy of a control condition, independent assessment of patients' performance (ie standardized ratings carried out by a person other than the music therapist) and the number of participants (no fewer than three). No randomised controlled trials, or trials with quantitative data suitable for analysis were found. The

  6. Skin symptoms in bakery and auto body shop workers: Associations with exposure and respiratory symptoms

    NARCIS (Netherlands)

    Arrandale, V.; Meijster, T.; Pronk, A.; Doekes, G.; Redlich, C.A.; Holness, D.L.; Heederik, D.

    2013-01-01

    Purpose: Despite the importance of skin exposure, studies of skin symptoms in relation to exposure and respiratory symptoms are rare. The goals of this study were to describe exposure-response relationships for skin symptoms, and to investigate associations between skin and respiratory symptoms in b

  7. Levothyroxine Poisoning - Symptoms and Clinical Outcome

    DEFF Research Database (Denmark)

    Nygaard, Birgitte; Saedder, Eva A.; Dalhoff, Kim

    2015-01-01

    Levothyroxine (LT), T4, poisoning is rarely associated with a severe outcome. However, cases with significant complications have been reported. The aim of this study was to identify factors associated with symptoms of poisoning including late-onset symptoms. All enquiries to the Danish Poison...... Information Centre (DPIC) concerning LT poisoning between March 2007 and September 2012 were reviewed and the following parameters were recorded: age, dose, time from ingestion, multiple drug intake and symptoms. To evaluate the frequency of late-onset symptoms, a subgroup of patients without initial symptoms...... patients, neither in children nor in adults (age 16-92 years) (p symptoms of poisoning at the time of enquiry; however, in 9 of 21 (43%) patients, we were able to contact, late-onset symptoms existed. In none of the cases...

  8. 20 CFR 416.928 - Symptoms, signs, and laboratory findings.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Symptoms, signs, and laboratory findings. 416....928 Symptoms, signs, and laboratory findings. (a) Symptoms are your own description of your physical... symptom(s), we will accept as a statement of this symptom(s) the description given by the person who...

  9. Asthma symptoms in obese adults

    DEFF Research Database (Denmark)

    Ulrik, Charlotte Suppli

    2016-01-01

    The association between asthma and obesity is well-described, but not straightforward, and according to current guidelines asthma control is more difficult to achieve in obese patients. The currently available studies evaluating response to pharmacological asthma therapy in obese patients show...... that these patients have an altered, in general less favorable, response to both reliever and controller medication compared to normal weight patients. However, at present, the limited available evidence precludes evidence-based recommendations. The 'obesity-related asthma' phenotype has different characteristics......, including association with atopy and type of airway inflammation, compared to 'classic' asthma. Furthermore, weight loss in patients with this phenotype leads to an improvement in symptoms, lung function, and airway responsiveness, as well as a reduction in medication utilization and hospital admissions...

  10. Nightmares in narcolepsy: underinvestigated symptom?

    Science.gov (United States)

    Pisko, Juraj; Pastorek, Lukas; Buskova, Jitka; Sonka, Karel; Nevsimalova, Sona

    2014-08-01

    Besides main disease symptoms, disturbing dreams are often found in narcoleptics and may contribute to disturbed sleep. Our main goal was to study different types of oneiric activity in narcolepsy with cataplexy (NC) and narcolepsy without cataplexy (N). We have analyzed the medical history of 118 narcoleptics (64 men, 86 with NC, 32 with N, mean age 41.6±15 years). Their most frequent dreams were divided into four groups: (A) low recall/mundane dreams, (B) vivid dreams without disturbing negative emotion, (C) nightmares, (D) reduction of nightmares, possibly by medication. Associations with other features of the disease were statistically analyzed. Nightmares were found in one-third of the patients, proportionally distributed in N and NC groups; not negatively charged vivid dreams appeared more frequently in NC patients (Pdreams occurred with higher prevalence in men (48%) than in women (20%), (Pdreaming activities appear to be closely related. Copyright © 2014 Elsevier B.V. All rights reserved.

  11. Symptom,sign and syndrome

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    930605 A study on clinical evaluation of theSHH for SAH.SONG Donglin(宋东林),et al.Dept Neurol,General Hosp,Air Force,PLA.,Beijing,100036.Chin J Nerv & Ment Dis 1993;19(1):6-8.The clinical evaluation of subhyaloid hemor-rhage(SHH)in 609 cases with subarachnoidhemorrhage(SAH)was studied by analysing 62patients with SHH(in both eyes in 35 cases andone eye in 27 cases).A comparision study be-tween the SHH group and non-SHH group wasmade,showing that the clinical symptoms in theSHH group were more severe,and had higher in-tracranial pressure and higher mortality.The au-topsy showed that in the 6 cases of SHH with oneeye the damaged eye was located on the same sidewith ruptured intracranial aneurysm.

  12. Systemic atherosclerosis and voiding symptom.

    Science.gov (United States)

    Yeniel, A Ozgur; Ergenoglu, A Mete; Meseri, Reci; Ari, Anıl; Sancar, Ceren; Itil, Ismail Mete

    2017-03-01

    To evaluate the effect of atherosclerosis on the storage and voiding symptoms of the bladder in women with overactive bladder (OAB). We retrospectively reviewed the charts of women with OAB who were evaluated between 2013 and 2015 in our urogynecology unit. Charts were assessed for history, examination findings, urinary diary, quality of life (QOL) questionnaires, urodynamic studies (UDSs), and four main risk factors for atherosclerosis: hypertension, diabetes mellitus, smoking, and hyperlipidemia. In a previous study, these were defined as vascular risk factors. Cases were excluded for insufficient data, diabetes mellitus with dysregulated blood glucose, or prolapse greater than 1cm to avoid confusing bladder outlet obstruction. We included 167 eligible cases in this study. We evaluated storage and voiding symptoms such as frequency, nocturia, residual urine volume, and voiding difficulties and UDS findings such as maximum bladder capacity, first desire, strong desire, detrusor overactivity, and bladder contractility index. The vascular risk score was categorized as "no risk" if the woman did not have any of the four risk factors and "at risk" if she had any of the factors. Independent sample t-test and chi-square tests were performed for analyses. Among the participants (n=167), 71.9% had at least one vascular risk factor. Those who were at risk were facing significantly more wet-type OAB (p=0.003) and nocturia (p=0.023). Moreover, mean age (p=0.008) and mean gravidity (p=0.020) were significantly higher in the at-risk group, whereas mean total nocturia QOL questionnaire scores (p=0.029) were significantly lower. Our findings suggest that aging and atherosclerosis may be associated with severe OAB and poorer QOL. Nocturia and related parameters of poor quality can be explained by impaired bladder neck perfusion. Future trials need to assess vascular and molecular changes in women with OAB. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Assessing effort: differentiating performance and symptom validity.

    Science.gov (United States)

    Van Dyke, Sarah A; Millis, Scott R; Axelrod, Bradley N; Hanks, Robin A

    2013-01-01

    The current study aimed to clarify the relationship among the constructs involved in neuropsychological assessment, including cognitive performance, symptom self-report, performance validity, and symptom validity. Participants consisted of 120 consecutively evaluated individuals from a veteran's hospital with mixed referral sources. Measures included the Wechsler Adult Intelligence Scale-Fourth Edition Full Scale IQ (WAIS-IV FSIQ), California Verbal Learning Test-Second Edition (CVLT-II), Trail Making Test Part B (TMT-B), Test of Memory Malingering (TOMM), Medical Symptom Validity Test (MSVT), WAIS-IV Reliable Digit Span (RDS), Post-traumatic Check List-Military Version (PCL-M), MMPI-2 F scale, MMPI-2 Symptom Validity Scale (FBS), MMPI-2 Response Bias Scale (RBS), and the Postconcussive Symptom Questionnaire (PCSQ). Six different models were tested using confirmatory factor analysis (CFA) to determine the factor model describing the relationships between cognitive performance, symptom self-report, performance validity, and symptom validity. The strongest and most parsimonious model was a three-factor model in which cognitive performance, performance validity, and self-reported symptoms (including both standard and symptom validity measures) were separate factors. The findings suggest failure in one validity domain does not necessarily invalidate the other domain. Thus, performance validity and symptom validity should be evaluated separately.

  14. A race riot's effect on psychological symptoms.

    Science.gov (United States)

    Greenley, J R; Gillespie, D P; Lindenthal, J J

    1975-09-01

    Certain individually stressful events have been observed to increase the psychological distress of persons affected; reduced psychological distress following other events has been attributed to collective processes, including increased group cohesion. These possibilities are investigated by contrasting reported symptom levels of 938 adults interviewed before, during, and after a racial riot. White suburbanites interviewed after the riot and urban black women interviewed during the riot report significantly fewer psychological symptoms. Hypotheses of seasonal symptom changes, sampling biases, and the absence of symptom changes among relatively unimpaired respondents are rejected, suggesting that reductions in symptom level are associated with the riot. Serious methodological problems are raised by our finding that such events may significantly affect not only rates but also patterns of reported psychological symptoms obtained through epidemiological studies.

  15. Symptom Patterns Among Gulf War Registry Veterans

    Science.gov (United States)

    Hallman, William K.; Kipen, Howard M.; Diefenbach, Michael; Boyd, Kendal; Kang, Han; Leventhal, Howard; Wartenberg, Daniel

    2003-01-01

    Objectives. We identify symptom patterns among veterans who believe they suffer from Gulf War–related illnesses and characterize groups of individuals with similar patterns. Methods. A mail survey was completed by 1161 veterans drawn from the Gulf War Health Registry. Results. An exploratory factor analysis revealed 4 symptom factors. A K-means cluster analysis revealed 2 groups: (1) veterans reporting good health and few moderate/severe symptoms, and (2) veterans reporting fair/poor health and endorsing an average of 37 symptoms, 75% as moderate/severe. Those in Cluster 2 were more likely to report having 1 or more of 24 medical conditions. Conclusions. These findings are consistent with previous investigations of symptom patterns in Gulf War veterans. This multisymptom illness may be more fully characterized by the extent, breadth, and severity of symptoms reported. PMID:12660208

  16. [Family functioning of elderly with depressive symptoms].

    Science.gov (United States)

    Souza, Rosely Almeida; Desani da Costa, Gislaine; Yamashita, Cintia Hitomi; Amendola, Fernanda; Gaspar, Jaqueline Correa; Alvarenga, Márcia Regina Martins; Faccenda, Odival; Oliveira, Maria Amélia de Campos

    2014-06-01

    To classify families of elderly with depressive symptoms regarding their functioning and to ascertain the presence of an association between these symptoms, family functioning and the characteristics of the elderly. This was an observational, analytical, cross-sectional study performed with 33 teams of the Family Health Strategy in Dourados, MS. The sample consisted of 374 elderly divided into two groups (with and without depressive symptoms). The instruments for data collection were a sociodemographic instrument, the GeriatricDepression Scale (15 items) and the Family Apgar. An association was observed between depressive symptoms and family dysfunction, female gender, four or more people living together, and physical inactivity. The functional family may represent effective support for the elderly with depressive symptoms, because it offers a comfortable environment that ensures the well-being of its members. The dysfunctional family can barely provide necessary care for the elderly, which can exacerbate depressive symptoms.

  17. Family functioning of elderly with depressive symptoms

    Directory of Open Access Journals (Sweden)

    Rosely Almeida Souza

    2014-06-01

    Full Text Available Objective: To classify families of elderly with depressive symptoms regarding their functioning and to ascertain the presence of an association between these symptoms, family functioning and the characteristics of the elderly. Method: This was an observational, analytical, cross-sectional study performed with 33 teams of the Family Health Strategy in Dourados, MS. The sample consisted of 374 elderly divided into two groups (with and without depressive symptoms. The instruments for data collection were a sociodemographic instrument, the GeriatricDepression Scale (15 items and the Family Apgar. Results: An association was observed between depressive symptoms and family dysfunction, female gender, four or more people living together, and physical inactivity. Conclusion: The functional family may represent effective support for the elderly with depressive symptoms, because it offers a comfortable environment that ensures the well-being of its members. The dysfunctional family can barely provide necessary care for the elderly, which can exacerbate depressive symptoms.

  18. Basic symptoms in schizophrenic and affective psychoses.

    Science.gov (United States)

    Ebel, H; Gross, G; Klosterkötter, J; Huber, G

    1989-01-01

    The study compares schizophrenic and affective psychoses with regard to basic symptoms. 30 patients in schizophrenic pre-, intra-, and postpsychotic basic stages and 30 patients in endogenous-depressive phases were examined according to the Bonn Scale for the Assessment of Basic Symptoms. The most important result is that certain cognitive basic symptoms and cenesthesias which are decisive for the development of florid productive-psychotic phenomena are found more frequently in the group of schizophrenias.

  19. Diagnostic validity of basic symptoms.

    Science.gov (United States)

    Klosterkötter, J; Ebel, H; Schultze-Lutter, F; Steinmeyer, E M

    1996-01-01

    Although the Bonn Scale for the Assessment of Basic Symptoms (BSABS) [13] has come into use in several European countries, its diagnostic validity has not yet been sufficiently examined. That is why we have assessed BSABS items on a sample of 243 consecutive admissions to the Department of Psychiatry at the RWTH University, Aachen, and 79 psychologically healthy persons. Then, a cluster analysis was calculated to identify the empirical item-grouping. Five well-interpretable BSABS subsyndromes were found. In addition, uni- and multivariate analyses were computed to evaluate the diagnostic validity of these subsyndromes. We were able to show that every BSABS subsyndrome separates at least schizophrenic, organic mental and affective disorders from personality, neurotic and substance-induced disorders, as well as from psychological health. Furthermore, the subsyndrome "information processing disturbances" differentiates between schizophrenic and organic mental disorders, on the one hand, and affective disorders, on the other, and additionally, the subsyndrome "interpersonal irritation" between schizophrenics and all other persons examined.

  20. Male hypogonadism: Symptoms and treatment

    Directory of Open Access Journals (Sweden)

    Peeyush Kumar

    2010-01-01

    Full Text Available Male hypogonadism is a condition in which the body does not produce enough of the testosterone hormone; the hormone that plays a key role in masculine growth and development during puberty. There is a clear need to increase the awareness of hypogonadism throughout the medical profession, especially in primary care physicians who are usually the first port of call for the patient. Hypogonadism can significantly reduce the quality of life and has resulted in the loss of livelihood and separation of couples, leading to divorce. It is also important for doctors to recognize that testosterone is not just a sex hormone. There is an important research being published to demonstrate that testosterone may have key actions on metabolism, on the vasculature, and on brain function, in addition to its well-known effects on bone and body composition. This article has been used as an introduction for the need to develop sensitive and reliable assays for sex hormones and for symptoms and treatment of hypogonadism.

  1. Symptoms Relevant to Surveillance for Ovarian Cancer

    Directory of Open Access Journals (Sweden)

    Robert M. Ore

    2017-03-01

    Full Text Available To examine how frequently and confidently healthy women report symptoms during surveillance for ovarian cancer. A symptoms questionnaire was administered to 24,526 women over multiple visits accounting for 70,734 reports. A query of reported confidence was included as a confidence score (CS. Chi square, McNemars test, ANOVA and multivariate analyses were performed. 17,623 women completed the symptoms questionnaire more than one time and >9500 women completed it more than one four times for >43,000 serially completed questionnaires. Reporting ovarian cancer symptoms was ~245 higher than ovarian cancer incidence. The positive predictive value (0.073% for identifying ovarian cancer based on symptoms alone would predict one malignancy for 1368 cases taken to surgery due to reported symptoms. Confidence on the first questionnaire (83.3% decreased to 74% when more than five questionnaires were completed. Age-related decreases in confidence were significant (p < 0.0001. Women reporting at least one symptom expressed more confidence (41,984/52,379 = 80.2% than women reporting no symptoms (11,882/18,355 = 64.7%, p < 0.0001. Confidence was unrelated to history of hormone replacement therapy or abnormal ultrasound findings (p = 0.30 and 0.89. The frequency of symptoms relevant to ovarian cancer was much higher than the occurrence of ovarian cancer. Approximately 80.1% of women expressed confidence in what they reported.

  2. What Are the Signs and Symptoms of Heart Disease?

    Science.gov (United States)

    ... Twitter. What Are the Signs and Symptoms of Heart Disease? The signs and symptoms of coronary heart disease ( ... will have signs and symptoms of the disease. Heart Disease Signs and Symptoms The illustration shows the major ...

  3. Children's perception of physical symptoms: The example of asthma.

    NARCIS (Netherlands)

    Rietveld, S.; Prins, P.J.M.; Lahey, B.B.; Kazdin, A.E.

    1998-01-01

    Introduces symptom perception as a concept to explain and understand the discordance between objective and subjective symptoms of disease. Contemporary models describing symptom perception and factors that influence these symptom perceptual processes are evaluated in light of recent empirical advant

  4. What Are the Symptoms of a Heart Attack?

    Science.gov (United States)

    ... from the NHLBI on Twitter. What Are the Symptoms of a Heart Attack? Not all heart attacks ... symptoms are called silent heart attacks. Most Common Symptoms The most common warning symptoms of a heart ...

  5. Negative symptoms in psychometrically defined schizotypy: The role of depressive symptoms.

    Science.gov (United States)

    Campellone, Timothy R; Elis, Ori; Mote, Jasmine; Sanchez, Amy H; Kring, Ann M

    2016-06-30

    People high in schizotypy, a risk factor for schizophrenia-spectrum disorders, can have negative symptoms, including diminished experience of motivation/pleasure (MAP) and emotional expressivity (EXP). Additionally, people high in schizotypy often report elevated depressive symptoms, which are also associated with diminished MAP and EXP. In this study, we examined whether negative symptoms were related to schizotypy above and beyond the presence of depressive symptoms. Thirty-one people high in schizotypy and 24 people low in schizotypy were administered the Clinical Assessment Interview for Negative Symptoms (CAINS), an interview-based measure of MAP and EXP negative symptoms and completed a self-report measure of cognitive and somatic-affective depressive symptoms. People high in schizotypy had more MAP negative symptoms than people low in schizotypy, but we found no group differences in EXP negative symptoms. Importantly, the relationship between MAP negative symptoms and schizotypy was fully mediated by cognitive depressive symptoms. These findings suggest that depressive symptoms, specifically cognitive depressive symptoms, may be a pathway for motivation and pleasure impairment, in people at elevated risk for developing schizophrenia-spectrum disorders.

  6. Nonmotor symptoms in genetic Parkinson disease

    DEFF Research Database (Denmark)

    Kasten, Meike; Kertelge, Lena; Brüggemann, Norbert

    2010-01-01

    To review current knowledge on nonmotor symptoms (NMS), particularly psychiatric features, in genetic Parkinson disease (PD) and to provide original data for genetic and idiopathic PD.......To review current knowledge on nonmotor symptoms (NMS), particularly psychiatric features, in genetic Parkinson disease (PD) and to provide original data for genetic and idiopathic PD....

  7. Time interval between concussions and symptom duration.

    Science.gov (United States)

    Eisenberg, Matthew A; Andrea, John; Meehan, William; Mannix, Rebekah

    2013-07-01

    To test the hypothesis that children with a previous history of concussion have a longer duration of symptoms after a repeat concussion than those without such a history. Prospective cohort study of consecutive patients 11 to 22 years old presenting to the emergency department of a children's hospital with an acute concussion. The main outcome measure was time to symptom resolution, assessed by the Rivermead Post-Concussion Symptoms Questionnaire (RPSQ). Patients and providers completed a questionnaire describing mechanism of injury, associated symptoms, past medical history, examination findings, diagnostic studies, and the RPSQ. Patients were then serially administered the RPSQ for 3 months after the concussion or until all symptoms resolved. A total of 280 patients were enrolled over 12 months. Patients with a history of previous concussion had a longer duration of symptoms than those without previous concussion (24 vs 12 days, P = .02). Median symptom duration was even longer for patients with multiple previous concussions (28 days, P = .03) and for those who had sustained a concussion within the previous year (35 days, P = .007) compared with patients without those risk factors. In a multivariate model, previous concussion, absence of loss of consciousness, age ≥13, and initial RPSQ score >18 were significant predictors of prolonged recovery. Children with a history of a previous concussion, particularly recent or multiple concussions, are at increased risk for prolonged symptoms after concussion. These findings have direct implications on the management of patients with concussion who are at high risk for repeat injuries.

  8. Predicting psychiatric symptoms among homeless people.

    Science.gov (United States)

    Calsyn, R J; Morse, G A

    1992-10-01

    Multiple regression was used to predict psychiatric symptoms among homeless people. The following variables were significant predictors of psychiatric symptoms: current life satisfaction, previous psychiatric hospitalization, the number of stressful life events, social support, problem drinking, and childhood unhappiness. The results are discussed in terms of their policy and practice implications, particularly the need for crisis intervention services and for dual-diagnosed clients.

  9. Somatic Symptoms in Traumatized Children and Adolescents

    Science.gov (United States)

    Kugler, Brittany B.; Bloom, Marlene; Kaercher, Lauren B.; Truax, Tatyana V.; Storch, Eric A.

    2012-01-01

    Childhood exposure to trauma has been associated with increased rates of somatic symptoms (SS), which may contribute to diminished daily functioning. One hundred and sixty-one children residing at a residential treatment home who had experienced neglect and/or abuse were administered the Trauma Symptom Checklist for Children (TSCC), the…

  10. Depressive symptoms in first-episode psychosis

    DEFF Research Database (Denmark)

    Sönmez, Nasrettin; Røssberg, Jan Ivar; Evensen, Julie

    2016-01-01

    AIMS: The present study examined if any patient characteristics at baseline predicted depressive symptoms at 10 years and whether patients prone to depressive symptoms in the first year of treatment had a different prognosis in the following years. METHOD: A total of 299 first-episode psychosis...

  11. Upper gastrointestinal symptoms in autoimmune gastritis

    Science.gov (United States)

    Carabotti, Marilia; Lahner, Edith; Esposito, Gianluca; Sacchi, Maria Carlotta; Severi, Carola; Annibale, Bruno

    2017-01-01

    Abstract Autoimmune gastritis is often suspected for its hematologic findings, and rarely the diagnosis is made for the presence of gastrointestinal symptoms. Aims of this cross-sectional study were to assess in a large cohort of patients affected by autoimmune gastritis the occurrence and the pattern of gastrointestinal symptoms and to evaluate whether symptomatic patients are characterized by specific clinical features. Gastrointestinal symptoms of 379 consecutive autoimmune gastritis patients were systematically assessed and classified following Rome III Criteria. Association between symptoms and anemia pattern, positivity to gastric autoantibodies, Helicobacter pylori infection, and concomitant autoimmune disease were evaluated. In total, 70.2% of patients were female, median age 55 years (range 17–83). Pernicious anemia (53.6%), iron deficiency anemia (34.8%), gastric autoantibodies (68.8%), and autoimmune disorders (41.7%) were present. However, 56.7% of patients complained of gastrointestinal symptoms, 69.8% of them had exclusively upper symptoms, 15.8% only lower and 14.4% concomitant upper and lower symptoms. Dyspepsia, subtype postprandial distress syndrome was the most represented, being present in 60.2% of symptomatic patients. Univariate and multivariate analyses showed that age gastritis is associated in almost 60% of cases with gastrointestinal symptoms, in particular dyspepsia. Dyspepsia is strictly related to younger age, no smoking, and absence of anemia. PMID:28072728

  12. Psychosocioeconomic study of medically unexplained physical symptoms

    Directory of Open Access Journals (Sweden)

    Maju Mathew Koola

    2012-01-01

    Full Text Available Background: There is a paucity of studies done on medically unexplained physical symptoms (MUPS in Kerala, India. The objective of this study was to examine the sociodemographic and other clinical variables associated with this condition. Materials and Methods: The clinical sample was taken from the General Medicine Clinic of a tertiary care hospital, in Kerala. The referred cases meeting the criteria (N=48 for medically unexplained physical symptoms were enrolled for this cross-sectional study. The medical doctor with experience in psychiatry completed the questionnaire. Results: Most of the patients were middle-aged females from rural areas. The most common symptom reported was headache. Most of the patients had symptoms for five years or more and had seen two-to-five consultants. A majority of the patients had undergone special investigations and a few had expensive and invasive investigations. Cluster C personality disorders were the most common associated personality disorders with medically unexplained physical symptoms. Conclusions: To our knowledge this is the first psychosocioeconomic study on medically unexplained physical symptoms, done in Kerala, India. Medically unexplained physical symptoms cause loss of productivity and economic burden and are a major public health problem. Future studies are warranted focusing on non-pharmacological treatment, psycho-education on mind-body association, and medical models on specific cytokines associated with medically unexplained physical symptoms for personalized management, and to examine the effect of a combination of pharmacotherapy and cognitive behavioral therapy.

  13. Signs and Symptoms of Congenital Heart Defects

    Science.gov (United States)

    ... Twitter. What Are the Signs and Symptoms of Congenital Heart Defects? Many congenital heart defects cause few or no signs and symptoms. A ... lips, and fingernails) Fatigue (tiredness) Poor blood circulation Congenital heart defects don't cause chest pain or other painful ...

  14. Atrophic vaginitis: signs, symptoms, and better outcomes.

    Science.gov (United States)

    Reimer, Annabelle; Johnson, Laura

    2011-01-01

    Atrophic vaginitis is a common finding in women with low estrogen states. Many women believe their symptoms are expected signs of aging. NPs can provide therapeutic options to improve vaginal health and quality of life. This article reviews physiology, clinical manifestations, signs, symptoms, and treatment methods for atrophic vaginitis.

  15. Common Cold in Babies: Symptoms and Causes

    Science.gov (United States)

    Common cold in babies Symptoms and causes By Mayo Clinic Staff The first indication of the common cold in a baby is often: A congested ... or green Other signs and symptoms of a common cold in a baby may include: Fever Sneezing ...

  16. Methodological issues in negative symptom trials.

    Science.gov (United States)

    Marder, Stephen R; Daniel, David G; Alphs, Larry; Awad, A George; Keefe, Richard S E

    2011-03-01

    Individuals from academia, the pharmaceutical industry, and the US Food and Drug Administration used a workshop format to discuss important methodological issues in the design of trials of pharmacological agents for improving negative symptoms in schizophrenia. The issues addressed included the need for a coprimary functional measure for registration trials; the characteristics of individuals who should enter negative symptom trials; the optimal duration for a proof-of-concept or registration trial; the optimal design of a study of a broad-spectrum agent that treats both positive and negative symptoms or a co-medication that is added to an antipsychotic; the relative strengths and weaknesses of available instruments for measuring negative symptoms; the definition of clinically meaningful improvement for these trials; and whether drugs can be approved for a subdomain of negative symptoms.

  17. Symptoms and syndromes of bodily distress

    DEFF Research Database (Denmark)

    Fink, Per; Toft, Tomas; Hansen, Morten Steen

    2007-01-01

    OBJECTIVE: Physical complaints not attributable to verifiable, conventionally defined diseases, i.e., medically unexplained or functional somatic symptoms, are prevalent in all medical settings, but their classification is contested as numerous overlapping diagnoses and syndrome labels have been...... introduced. This study aims to determine whether functional somatic symptoms cluster into distinct syndromes and diagnostic entities. METHODS: The 978 consecutively admitted patients from a neurological department (n = 120), a medical department (n = 157), and from primary care (n = 701) were interviewed...... using the Schedules for Clinical Assessment in Neuropsychiatry (SCAN) diagnostic instrument. RESULTS: Patients complained of a median of five functional somatic symptoms; women of six, men of four (p symptoms stood out as distinctive for patients with multiple symptoms. Principal...

  18. Fatigue and Depressive Symptoms in Older People

    DEFF Research Database (Denmark)

    Mänty, Minna; Rantanen, Taina; Era, Pertti

    2014-01-01

    Fatigue is considered an important indicator of aging-related declines in health and functional abilities. Previous studies have indicated strong associations between fatigue and depressive symptoms among younger populations and in patient groups with specific diseases. However, it is not known how...... different measures of fatigue are associated with depressive symptoms among general older populations. The purpose of this study is to describe the prevalence of depressive symptoms among community-dwelling older adults reporting mobility-related or general feelings fatigue. The study population consisted...... of 75-year-old community-living individuals (n = 561). Both, mobility-related and general fatigue, were associated in a stepwise relationship with depressive symptoms: a higher level of fatigue was related to higher level of depressive symptoms. Especially major general fatigue was strongly associated...

  19. Symptoms of Nerve Dysfunction After Hip Arthroscopy

    DEFF Research Database (Denmark)

    Dippmann, Christian; Thorborg, Kristian; Kraemer, Otto

    2014-01-01

    PURPOSE: The primary purpose of this study was to analyze the rate, pattern, and severity of symptoms of nerve dysfunction after hip arthroscopy (HA) by reviewing prospectively collected data. The secondary purpose was to study whether symptoms of nerve dysfunction were related to traction time...... year after HA concerning symptoms of nerve dysfunction, possible localization, and erectile dysfunction. Fifty patients participated and returned fully completed questionnaires. Patients reporting symptoms of nerve dysfunction 1 year after HA were re-examined. RESULTS: Twenty-three of 50 patients (46......%) reported symptoms of nerve dysfunction during the first week after HA; this was reduced to 14 patients (28%) after 6 weeks, 11 patients (22%) after 26 weeks, and 9 patients (18%) after 1 year. One patient experienced temporary erectile dysfunction. No difference in traction time between patients...

  20. The symptom intensity scale, fibromyalgia, and the meaning of fibromyalgia-like symptoms

    NARCIS (Netherlands)

    Wolfe, Frederick; Rasker, Johannes J.

    2006-01-01

    OBJECTIVE: To characterize a scale for the measurement of fibromyalgia (FM)-like symptoms; to investigate whether FM is a discrete disorder; to understand the significance of FM-like symptoms; and to investigate causal and noncausal factors in the development of such symptoms. METHODS: We evaluated

  1. The symptom intensity scale, fybromyalgia, and the meaning of fybromyalgia-like symptoms

    NARCIS (Netherlands)

    Wolfe, Frederick; Rasker, Hans J.

    2006-01-01

    OBJECTIVE: To characterize a scale for the measurement of fibromyalgia (FM)-like symptoms; to investigate whether FM is a discrete disorder; to understand the significance of FM-like symptoms; and to investigate causal and noncausal factors in the development of such symptoms. METHODS: We evaluated

  2. Determinants of Menopausal Symptoms among Ghanaian Women

    Directory of Open Access Journals (Sweden)

    Jacob Setorglo

    2012-07-01

    Full Text Available The onset of menopause is unique to every woman with varying symptoms which have implications on health and well-being. This study evaluated the perception, knowledge and beliefs about menopause and the prevalence of climacteric symptoms. The study was a cross-sectional survey of 280 menopausal women aged 45 years and older in the Accra Metropolis of the Greater Accra Region of Ghana. Data on socio-demographic characteristics, knowledge, beliefs and experience of menopausal symptoms were collected using a semi-structured questionnaire. Anthropometric data on weight, height, % body fat and MUAC were also taken. All data were analyzed using SPSS version 16.0 and presented as means and frequencies. Predictors of menopausal symptoms were determined by logistic regression. The mean age of onset of menopause was (48±2.9 years with 98.2% having some knowledge of the signs and symptoms of menopause. The most frequently reported menopausal symptoms by the women were: night sweats (83.2%, hot flashes (76.4%, mood swings (72.5% and vaginal dryness (71.4%. The significant predictors for the occurrence of the most common symptoms reported were: age at onset of menstruation, age of start of menopause, body weight and % body fat. There was a decreased risk of experiencing symptoms such as night sweats, mood swings and vaginal dryness as age at menopause increased. Menopausal transition was determined by both vasomotor and urogenital symptoms. Counseling and support are needed to enable women manage the symptoms better. Most women have heard of and know what menopause is.

  3. Pesticides and respiratory symptoms among farmers

    Directory of Open Access Journals (Sweden)

    Faria Neice Müller Xavier

    2005-01-01

    Full Text Available OBJECTIVE: Despite the intensive use of pesticides in agriculture there are few studies assessing the risk of respiratory conditions from this exposure. The study aimed at quantifying the prevalence of respiratory symptoms among farmers and evaluating its relationship with occupational use of pesticides and the prevalence of respiratory symptoms. METHODS: A cross-sectional study was conducted among 1,379 farmers from two municipalities of Southern Brazil in 1996. Frequency and type of chemical exposure and pesticide poisoning were recorded for both sexes. All subjects aged 15 years or older with at least 15 weekly hours of agricultural activity were interviewed. An adapted questionnaire developed by the American Thoracic Society was used for the assessment of respiratory symptoms. Multivariate logistic regression analysis was carried out. RESULTS: More than half (55% of interviewees were male. The prevalence of asthma symptoms was 12% and chronic respiratory disease symptoms was 22%. Higher odds ratios for both asthma (OR=1.51; 95% CI: 1.07-2.14 and chronic respiratory disease (OR=1.34; 95% CI 1.00-1.81 symptoms were found in women. Logistic regression analysis identified associations between many forms of exposure to pesticides and increased respiratory symptoms. Occurrence of pesticide poisoning was associated with higher prevalence of asthma symptoms (OR=1.54; 95% CI: 1.04-2.58 and chronic respiratory disease symptoms (OR=1.57; 95% CI: 1.08-2.28. CONCLUSIONS: In spite of causality limitations, the study results provide evidence that farming exposure to pesticides is associated with higher prevalence of respiratory symptoms, especially when the exposure is above two days per month.

  4. Gastrointestinal Symptoms in Lysosmal Disease

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    Farid IMANZADEH

    2012-12-01

    Full Text Available  How to Cite this Article: Imanzadeh F. Gastrointestinal Symptoms in Lysosmal Disease. Iran J Child Neurol Autumn 2012; 6:4 (suppl. 1:17-18.pls see PDF. References: 1. Semenza  GL,  Pyeritz  RE.  Respiratory complications of mucopolysaccharide storage disorders. Medicine (Baltimore 1988; 67:209. 2.   Wraith   JE,   Scarpa   M,   Beck   M,   et   al. Mucopolysaccharidosis type II (Hunter syndrome: a clinical review and recommendations for treatment in the era of enzyme replacement therapy. Eur J Pediatr 2008; 167:267. 3. Stevens JM, Kendall BE, Crockard HA, Ransford   A.   The   odontoid   process   in Morquio-Brailsford’s disease. The effects of occipitocervical fusion. J Bone Joint Surg Br 1991; 73:851. 4.   Jones AE, Croley TF. Morquio syndrome and anesthesia. Anesthesiology 1979; 51:261. 5.   Ashraf J, Crockard HA, Ransford AO, Stevens JM. Transoral decompression and posterior stabilisation in Morquio’s disease. Arch Dis Child 1991; 66:1318. 6.  Neufeld EF, Muenzer J. The metabolic and molecular bases of inherited disease, Scriver C, Beaudet AL, Valle D, Sly W (Eds, McGraw- Hill, New York 2001. p.3421. 7.   Wraith   JE.   The   mucopolysaccharidoses:   a clinical review and guide to management. Arch Dis Child 1995; 72:263. 8.   Cleary MA, Wraith JE. The presenting features of mucopolysaccharidosis type IH (Hurler syndrome. Acta Paediatr 1995; 84:337. 9.   Elsner B. Ultrastructure of the rectal wall in Hunter’s   syndrome.   Gastroenterology   1970; 58:856. 10. Cleary   MA,   Wraith   JE.   Management   of mucopolysaccharidosis type III. Arch Dis Child 1993; 69:403. 

  5. Gender, depressive symptoms, and daily cigarette use.

    Science.gov (United States)

    Bares, Cristina B

    2014-01-01

    It is widely known that cigarette use and depressive symptoms co-occur during adolescence and young adulthood and that there are gender differences in smoking initiation, progression, and co-occurrence with other drug use. Given that females have an earlier onset of depressive symptoms while males have an earlier onset of cigarette use, this study explored the possible bidirectional development of cigarette use and depressive symptoms by gender across the transition from adolescence to young adulthood. Gender differences in the stability and crossed effects of depressive symptoms and cigarette smoking during the transition to young adulthood, controlling for other known risk factors, were examined using a nationally representative longitudinal sample. A bivariate autoregressive multi-group structural equation model examined the longitudinal stability and crossed relationships between a latent construct of depressive symptoms and cigarette smoking over four waves of data. Data for this study came from four waves of participants (N = 6,501) from the National Longitudinal Survey of Adolescent Health. At each of four waves, participants completed a battery of measures including questions on depressive symptoms and an ordinal measure of number of cigarettes smoked per day. The best-fitting bivariate autoregressive models were gender-specific, included both crossed and parallel associations between depressive symptoms and cigarette use during the transition to adulthood, and controlled for wave-specific parental smoking, alcohol use, and number of friends who smoke. For females, greater depressive symptoms at each wave, except the first one, were associated with greater subsequent cigarette use. There were bidirectional associations between depressive symptoms and cigarette use only for females during young adulthood, but not for males. The development of depressive symptoms and cigarette use from adolescence and into young adulthood follows similar patterns for males

  6. Effects of quitting cannabis on respiratory symptoms

    Science.gov (United States)

    Hancox, Robert J.; Shin, Hayden H.; Gray, Andrew R.; Poulton, Richie; Sears, Malcolm R.

    2016-01-01

    Smoking cannabis is associated with symptoms of bronchitis. Little is known about the persistence of symptoms after stopping cannabis use. We assessed associations between changes in cannabis use and respiratory symptoms in a population-based cohort of 1037 young adults. Participants were asked about cannabis and tobacco use at ages 18, 21, 26, 32 and 38 years. Symptoms of morning cough, sputum production, wheeze, dyspnoea on exertion and asthma diagnoses were ascertained at the same ages. Frequent cannabis use was defined as ≥52 occasions over the previous year. Associations between frequent cannabis use and respiratory symptoms were analysed using generalised estimating equations with adjustments for tobacco smoking, asthma, sex and age. Frequent cannabis use was associated with morning cough (OR 1.97, pcannabis use was associated with reductions in the prevalence of cough, sputum and wheeze to levels similar to nonusers. Frequent cannabis use is associated with symptoms of bronchitis in young adults. Reducing cannabis use often leads to a resolution of these symptoms. PMID:25837035

  7. Symptoms Relevant to Surveillance for Ovarian Cancer.

    Science.gov (United States)

    Ore, Robert M; Baldwin, Lauren; Woolum, Dylan; Elliott, Erika; Wijers, Christiaan; Chen, Chieh-Yu; Miller, Rachel W; DeSimone, Christopher P; Ueland, Frederick R; Kryscio, Richard J; Nagell, John R van; Pavlik, Edward J

    2017-03-20

    To examine how frequently and confidently healthy women report symptoms during surveillance for ovarian cancer. A symptoms questionnaire was administered to 24,526 women over multiple visits accounting for 70,734 reports. A query of reported confidence was included as a confidence score (CS). Chi square, McNemars test, ANOVA and multivariate analyses were performed. 17,623 women completed the symptoms questionnaire more than one time and >9500 women completed it more than one four times for >43,000 serially completed questionnaires. Reporting ovarian cancer symptoms was ~245 higher than ovarian cancer incidence. The positive predictive value (0.073%) for identifying ovarian cancer based on symptoms alone would predict one malignancy for 1368 cases taken to surgery due to reported symptoms. Confidence on the first questionnaire (83.3%) decreased to 74% when more than five questionnaires were completed. Age-related decreases in confidence were significant (p replacement therapy or abnormal ultrasound findings (p = 0.30 and 0.89). The frequency of symptoms relevant to ovarian cancer was much higher than the occurrence of ovarian cancer. Approximately 80.1% of women expressed confidence in what they reported.

  8. Prevalence of andropausal symptoms among Kuwaiti males.

    Science.gov (United States)

    Maha, Al-Sejari

    2013-11-01

    Andropause is a syndrome that usually occurs during men's midlife. It is associated with clinical short-term and long-term effects, as well as some physiological and psychological symptoms due to subnormal levels of testosterone serum. The objective of this study was to identify the factors that significantly contribute to the prevalence of symptoms that may be related to androgen deficiency. The study used a cross-sectional structured questionnaire and a sample of 214 Kuwaiti men aged 40 years and older. The questionnaire consisted of the sociodemographic characteristics of the participants and the Androgen Deficiency of the Aging Male Scale of Andropausal Symptoms. The results of the study indicate that Kuwaiti men who were 40 to 49 years old reported fewer symptoms than did Kuwaiti men aged 50 years and older, including deterioration in their ability to play sports, easily falling asleep after dinner, anger, and hot flushes (p sport performance, sweating, loss of height, decreased libido, as well as falling asleep after dinner. For those aged 40 to 49 years, lower education levels, marital status, and employment status were significantly associated with the men's symptoms (p < .05). On the other hand, in the case of respondents aged 50 years and older, only education level was significantly associated with their symptoms (p < .05). This is a preliminary study that reports the prevalence of aging male symptoms among Kuwaiti men. The findings will offer insight into the necessary health care provisions to educate, treat, and provide information related to andropause for the general public.

  9. Anxiety symptoms during pregnancy and postpartum.

    Science.gov (United States)

    Breitkopf, Carmen Radecki; Primeau, Loree A; Levine, Ruth E; Olson, Gayle L; Wu, Z Helen; Berenson, Abbey B

    2006-09-01

    This cross-sectional study compared the distribution of anxiety symptoms among pregnant, non-pregnant, and postpartum women of lower socioeconomic status. Participants were 807 women who were pregnant (24-36 weeks), postpartum (2-8 weeks), or not pregnant. Anxiety and depressive symptoms were assessed by the state-trait anxiety index and the Beck depression inventory, respectively. English and Spanish versions of the instrument were available. Group differences in anxiety were evaluated using analysis of variance. Multivariate regression was performed to evaluate differences in anxiety while controlling for marital status, education, race/ethnicity, employment, cohabitation, income, parity, history of depression/anxiety, and depressive symptoms. Anxiety scores were lower among postpartum women relative to pregnant and non-pregnant women (both P < 0.001), who did not differ (P = 0.99). After controlling for depressive symptoms and patient characteristics, anxiety remained lowest among postpartum women. Additionally, history of depression/anxiety and depressive symptoms were significant predictors of anxiety in the multivariate analysis. Comparatively low anxiety and depressive symptoms were observed among women who were 2-8 weeks postpartum. Anxiety symptoms that occur postpartum may not appear until later in the postpartum period.

  10. Mediators between bereavement and somatic symptoms

    Directory of Open Access Journals (Sweden)

    Konkolÿ Thege Barna

    2012-06-01

    Full Text Available Abstract Background In our research we examined the frequency of somatic symptoms among bereaved (N = 185 and non-bereaved men and women in a national representative sample (N = 4041 and investigated the possible mediating factors between bereavement status and somatic symptoms. Methods Somatic symptoms were measured by the Patient Health Questionnaire (PHQ-15, anxiety with a four-point anxiety rating scale, and depression with a nine-item shortened version of the Beck Depression Inventory. Results Among the bereaved, somatic symptoms proved to be significantly more frequent in both genders when compared to the non-bereaved, as did anxiety and depression. On the multivariate level, the results show that both anxiety and depression proved to be a mediator between somatic symptoms and bereavement. The effect sizes indicated that for both genders, anxiety was a stronger predictor of somatic symptoms than depression. Conclusions The results of our research indicate that somatic symptoms accompanying bereavement are not direct consequences of this state but they can be traced back to the associated anxiety and depression. These results draw attention to the need to recognize anxiety and depression looming in the background of somatic complaints in bereavement and to the importance of the dissemination of related information.

  11. Evaluation and treatment of postconcussive symptoms.

    Science.gov (United States)

    McAllister, Thomas W; Arciniegas, David

    2002-01-01

    Postconcussive symptoms such as headache, dizziness, irritability, and difficulties with memory and attention are reported frequently after traumatic brain injuries (TBI) of all severities. The etiology of these symptoms in individuals with mild TBI has been a subject of some controversy with theories ranging from neural damage to malingering. Furthermore, although the term postconcussive syndrome is commonly used clinically and in the scientific literature, it is not clear that postconcussive symptoms constitute a syndrome per se. Instead, it may be the case that the various symptoms that commonly co-occur after TBI are relatively independent consequences of a single neurological event. In other words, because the locations and severity of injury vary between individuals despite ostensibly similar injuries, it follows that there should be variations in symptom type and severity between individuals as well. This article reviews the sequelae and natural course of recovery from mild TBI, the evidence regarding both persistent postconcussive symptoms and the postconcussive syndrome, and outlines an approach to the assessment and treatment of individuals with these symptoms after TBI.

  12. Coparenting Behaviors as Mediators Between Postpartum Parental Depressive Symptoms and Toddler’s Symptoms

    Directory of Open Access Journals (Sweden)

    Hervé Tissot

    2016-12-01

    Full Text Available Postpartum parental depression, even of mild intensity and short duration, has negative consequences on child development, including increased externalizing and internalizing symptoms. Studies revealed that the links between parental depression and child development are mediated by parenting difficulties. On the other hand, the mediating role of problematic family-level relationships, such as low coparenting support and high conflict between the parents, has rarely been considered, although coparenting difficulties have been linked with both increased depressive symptoms in parents and increased symptoms in toddlers. In the present study, we proposed testing a comprehensive mediation model linking parental depression, coparenting, and child symptoms. At 3 months postpartum, a convenience sample of 69 parental couples completed the Edinburgh Postnatal Depression Scale. In addition, we assessed levels of coparenting support and conflict during a mother–father–infant play situation, the Lausanne Trilogue Play. At 18 months postpartum, both parents assessed child symptoms with the Symptom Checklist Questionnaire. The results showed that coparenting support mediated the links between parental depressive symptoms and child symptoms, but only for mothers: Maternal depressive symptoms were linked with lower coparenting support, which in turn predicted increased psychofunctional symptoms and behavior problems assessed by mothers. Although coparenting conflict behaviors were not predicted by parents’ depressive symptoms, higher conflict was unexpectedly linked with fewer behavior problems assessed by both parents. The present study allowed us to unveil complex pathways between mild parental mood disturbances, family-level relationships, and child development in the first months of the child’s life.

  13. Vulvar symptoms in paediatric and adolescent patients.

    Science.gov (United States)

    Piippo, S; Lenko, H; Vuento, R

    2000-04-01

    Vulvovaginal symptoms in children and young adolescents are not yet very well understood, nor is the actual incidence known. This study evaluates the character and possible infectious aetiology of vulvar symptoms of females aged up to 16 y. The signs, symptoms and bacteriological findings of 68 consecutive cases were studied. The study was conducted in the University Hospital of Tampere at a special gynaecological consultation clinic for children and adolescents. Sixty-eight patients were included in the study: 48 girls (71%) were prepubertal, at Tanner stage M1P1, 26 patients were 2-4-y-old and 15 were 5-7-y-old. The duration of symptoms was known for 46 patients: 41% had had symptoms for >1 mo and 20% for >6 mo. Forty-eight patients had abnormal clinical findings on examination and 16 (33%) of them had an infectious aetiology. Streptococcus pyogenes infection was identified in 11 (16%) patients, all of whom had symptoms. Candida was identified in 6 (9%) patients. No infectious aetiology was found among 26 patients who had symptoms and abnormal clinical findings. Vulvovaginal symptoms during childhood are more common among younger children (<7 y). In 67% of patients no infectious aetiology could be found. Samples for microbiological culture should be taken from symptomatic patients and symptomatic areas. Cultures of Candida and bacteria are necessary but usually sufficient. If a microbiological aetiology is established, treatment can be assigned accordingly. Patients with vulvar symptoms and findings but with an unclear aetiology need support and advice on proper hygiene and can intermittently use mild corticosteroids locally.

  14. Symptoms in smokers trying to quit

    Directory of Open Access Journals (Sweden)

    Helgason Asgeir R

    2006-08-01

    Full Text Available Abstract Aims To describe the prevalence and intensity of different symptoms in relation to tobacco abstinence. To explore latent dimensions between symptoms in smokers trying to quit. Design A cross sectional study using a questionnaire to retrospectively assess symptoms over a period of 12 months. Setting Swedish telephone quitline, a nationwide free of charge service. Participants All 741 individuals who had called the quitline and signed up for smoking cessation treatment between February 2000 to November 2001 and reported to have been smoke free for at least 24 hours during the previous 12 month period from first contact. Measurements Assessments were made by self-report, and abstinence was defined as "not a single puff of smoke during the last week". A factor analysis approach where individual items aggregate into factors was used to explore the relationship between the different symptoms. Findings High intensity of symptoms related to unsuccessful quitting attempts and included craving, irritability, apprehension/anxiety, difficulties concentrating, restlessness, depression/depressed mood, and insomnia. The factor loadings of all 17 symptoms resulted in three factors with factor 1, psychological being the most important. High scores on this factor relates to unsuccessful quitting attempts. Using Nicotine Replacement Therapy (NRT for 5 weeks or longer, reduced symptoms included in factor 1. The other two factors were factor 2 physiological and factor 3 neurological. Conclusion Symptoms that are psychological and/or neurological in nature are interrelated and appear to be the most significant obstacles for successful quitting attempts in a population-based setting. These symptoms may be successfully treated with NRT.

  15. Symptoms in smokers trying to quit

    Directory of Open Access Journals (Sweden)

    Helgason Asgeir R

    2006-08-01

    Full Text Available Abstract Aims To describe the prevalence and intensity of different symptoms in relation to tobacco abstinence. To explore latent dimensions between symptoms in smokers trying to quit. Design A cross sectional study using a questionnaire to retrospectively assess symptoms over a period of 12 months. Setting Swedish telephone quitline, a nationwide free of charge service. Participants All 741 individuals who had called the quitline and signed up for smoking cessation treatment between February 2000 to November 2001 and reported to have been smoke free for at least 24 hours during the previous 12 month period from first contact. Measurements Assessments were made by self-report, and abstinence was defined as "not a single puff of smoke during the last week". A factor analysis approach where individual items aggregate into factors was used to explore the relationship between the different symptoms. Findings High intensity of symptoms related to unsuccessful quitting attempts and included craving, irritability, apprehension/anxiety, difficulties concentrating, restlessness, depression/depressed mood, and insomnia. The factor loadings of all 17 symptoms resulted in three factors with factor 1, psychological being the most important. High scores on this factor relates to unsuccessful quitting attempts. Using Nicotine Replacement Therapy (NRT for 5 weeks or longer, reduced symptoms included in factor 1. The other two factors were factor 2 physiological and factor 3 neurological. Conclusion Symptoms that are psychological and/or neurological in nature are interrelated and appear to be the most significant obstacles for successful quitting attempts in a population-based setting. These symptoms may be successfully treated with NRT.

  16. Multiple perspectives on symptom interpretation in primary care research

    DEFF Research Database (Denmark)

    Rosendal, Marianne; Jarbøl, Dorte Ejg; Pedersen, Anette Fischer;

    2013-01-01

    BACKGROUND: Assessment and management of symptoms is a main task in primary care. Symptoms may be defined as 'any subjective evidence of a health problem as perceived by the patient'. In other words, symptoms do not appear as such; symptoms are rather the result of an interpretation process. We a......, including medicalisation of normal phenomena and devaluation of medically unexplained symptoms. Future research in primary care could gain from exploring symptoms as a generic phenomenon and raised awareness of symptom complexity....

  17. Predictors of neurobehavioral symptoms in a university population: a multivariate approach using a postconcussive symptom questionnaire.

    Science.gov (United States)

    Ettenhofer, Mark L; Reinhardt, Lindsay E; Barry, David M

    2013-10-01

    Several factors have been linked to severity of postconcussive-type (neurobehavioral) symptoms. In this study, predictors of neurobehavioral symptoms were examined using multivariate methods to determine the relative importance of each. Data regarding demographics, symptoms, current alcohol use, history of traumatic brain injury (TBI), orthopedic injuries, and psychiatric/developmental diagnoses were collected via questionnaire from 3027 university students. The most prominent predictors of symptoms were gender, history of depression or anxiety, history of attention-deficit/hyperactivity disorder or learning disability diagnosis, and frequency of alcohol use. Prior mild TBI was significantly related to overall symptoms, but this effect was small in comparison to other predictors. These results provide further evidence that neurobehavioral symptoms are multi-determined phenomena, and highlight the importance of psychiatric comorbidity, demographic factors, and health behaviors to neurobehavioral symptom presentation after mild TBI.

  18. Computer use, sleep duration and health symptoms

    DEFF Research Database (Denmark)

    Nuutinen, Teija; Roos, Eva; Ray, Carola

    2014-01-01

    and Denmark in 2010, including data on 5,402 adolescents (mean age 15.61 (SD 0.37), girls 53 %). Symptoms assessed included feeling low, irritability/bad temper, nervousness, headache, stomachache, backache, and feeling dizzy. We used structural equation modeling to explore the mediating effect of sleep...... duration on the association between computer use and symptom load. RESULTS: Adolescents slept approximately 8 h a night and computer use was approximately 2 h a day. Computer use was associated with shorter sleep duration and higher symptom load. Sleep duration partly mediated the association between...

  19. Symptoms and biomarkers associated with celiac disease

    DEFF Research Database (Denmark)

    Kårhus, Line L; Thuesen, Betina H; Rumessen, Jüri J

    2016-01-01

    with having been diagnosed and 71% felt better on a gluten-free diet. CONCLUSION: There were no differences in the prevalence of symptoms between participants with and without screening-detected celiac disease, confirming that risk stratification in a general population by symptoms is difficult. The majority...... of participants diagnosed with celiac disease felt better on a gluten-free diet despite not reporting abdominal symptoms before diagnosis and participants in the clinical evaluation were generally satisfied with participation in the screening program....

  20. [Psychiatric symptoms can reveal Turner syndrome].

    Science.gov (United States)

    Thusgaard, Helle; Arnfred, Sidse Marie H

    2013-02-01

    Turner syndrome is usually diagnosed by physical characteristics, i.e. low height and infertility. This case report presents a woman, who was referred to a chromosome analysis at the age of 35 years, due to a specific pattern of psychiatric symptoms. She felt childish, had strong emotional bonds to her family, yet lacked friendships and intimate relationships. She had moderate symptoms of obsessive-compulsive disorder with a sexual content. Confronted with this constellation of symptoms, psychiatrists and psychologists should be aware of Turner syndrome.

  1. Presenting Symptoms of Chiari Type I Malformation

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2009-06-01

    Full Text Available Clinical and radiographic predictors of neurologic symptoms were investigated in a population-based retrospective study of 51 children identified with Chiari I malformation at the University of California, and Kaiser Department of Radiology, San Francisco.

  2. Psychotic Symptoms Associated with Left Caudate Infarction

    Directory of Open Access Journals (Sweden)

    Ying-Chih Cheng

    2015-09-01

    Full Text Available Psychotic symptoms following acquired brain lesion are relatively rare, and thus, the specific association linking such symptoms to the distinct brain structure remains unclear. The frontal–subcortical circuits are thought to modulate motor activity and human behavior, and have been reported to be associated with many neuropsychiatric symptoms. We herein report the case of a 77-year-old man without previous psychiatric disorder who developed a new onset of psychotic symptoms following left caudate infarction. The presented case supports the fact that psychosis might arise from alteration of the distinct brain structure. The functional impairment of the frontal–subcortical circuits may be a critical factor linking the pathogenesis of psychosis associated with acquired brain lesion.

  3. Periodontal (Gum) Disease: Causes, Symptoms, and Treatments

    Science.gov (United States)

    ... for providing oral care. NIDCR > OralHealth > Topics > Gum (Periodontal) Diseases > Periodontal (Gum) Disease: Causes, Symptoms, and Treatments Periodontal ( ... U.S. currently have some form of the disease. Periodontal diseases range from simple gum inflammation to serious disease ...

  4. Seasonal Allergies: Symptoms, Diagnosis, and Treatment

    Science.gov (United States)

    ... usually used in combination with antihistamines. Long-term usage of spray decongestants can actually make symptoms worse, ... Contact Us | Viewers & Players Friends of the National Library of Medicine (FNLM)

  5. Lower Back Pain Symptom Checker Flowchart

    Science.gov (United States)

    ... of the back. Some causes and treatment of back pain are described in this chart.Our trusted Symptom ... Problems Hip Problems Knee Problems Leg Problems Lower Back Pain Menstrual Cycle Problems Mouth Problems Mouth Problems in ...

  6. What Are the Symptoms of Osteogenesis Imperfecta?

    Science.gov (United States)

    ... Resources and Publications What are the symptoms of osteogenesis imperfecta (OI)? Skip sharing on social media links Share ... decline and inability to breathe. 2 , 3 , 4 Osteogenesis Imperfecta Foundation. (2008). Respiratory issues in osteogenesis imperfecta. Retrieved ...

  7. Women's Heart Disease: Heart Attack Symptoms

    Science.gov (United States)

    ... this page please turn JavaScript on. Feature: Women's Heart Disease Heart Attack Symptoms Past Issues / Winter 2014 Table ... NHLBI has uncovered some of the causes of heart diseases and conditions, as well as ways to prevent ...

  8. Signs and Symptoms of Cervical Cancer

    Science.gov (United States)

    ... Detection, Diagnosis, and Staging Signs and Symptoms of Cervical Cancer Women with early cervical cancers and pre-cancers ... Ask Your Doctor About Cervical Cancer? More In Cervical Cancer About Cervical Cancer Causes, Risk Factors, and Prevention ...

  9. Symptoms of Major Depression and Complicated Grief

    Science.gov (United States)

    ... Loss of a Loved One Symptoms of major depression and complicated grief Depression It’s common for people to have sadness, pain, ... ball game; reading a good book; listening to music; or getting a massage or manicure. Prepare for ...

  10. Feature Hepatitis: Hepatitis Symptoms, Diagnosis, Treatment & Prevention

    Science.gov (United States)

    ... Navigation Bar Home Current Issue Past Issues Feature Hepatitis Hepatitis: Symptoms, Diagnosis, Treatment & Prevention Past Issues / Spring 2009 ... No appetite Fever Headaches Diagnosis To check for hepatitis viruses, your doctor will test your blood. You ...

  11. Signs and Symptoms of Thyroid Cancer

    Science.gov (United States)

    ... Detection, Diagnosis, and Staging Signs and Symptoms of Thyroid Cancer Thyroid cancer can cause any of the following ... Health Care Team About Thyroid Cancer? More In Thyroid Cancer About Thyroid Cancer Causes, Risk Factors, and Prevention ...

  12. Home Care Nursing Improves Cancer Symptom Management

    Science.gov (United States)

    Home care nursing (HCN) improves the management of symptoms in breast and colorectal cancer patients who take the oral chemotherapy drug capecitabine, according to a study published online November 16 in the Journal of Clinical Oncology.

  13. Modified Protein Improves Vitiligo Symptoms in Mice

    Science.gov (United States)

    ... 2013 (historical) Modified Protein Improves Vitiligo Symptoms in Mice Altering a key protein involved in the development ... pigmentation loss associated with the skin disorder in mice, according to recent research funded by the NIH’s ...

  14. Personality trait predictors of bipolar disorder symptoms.

    Science.gov (United States)

    Quilty, Lena Catherine; Sellbom, Martin; Tackett, Jennifer Lee; Bagby, Robert Michael

    2009-09-30

    The purpose of the current investigation was to examine the personality predictors of bipolar disorder symptoms, conceptualized as one-dimensional (bipolarity) or two-dimensional (mania and depression). A psychiatric sample (N=370; 45% women; mean age 39.50 years) completed the Revised NEO Personality Inventory and the Minnesota Multiphasic Personality Inventory -2. A model in which bipolar symptoms were represented as a single dimension provided a good fit to the data. This dimension was predicted by Neuroticism and (negative) Agreeableness. A model in which bipolar symptoms were represented as two separate dimensions of mania and depression also provided a good fit to the data. Depression was associated with Neuroticism and (negative) Extraversion, whereas mania was associated with Neuroticism, Extraversion and (negative) Agreeableness. Symptoms of bipolar disorder can be usefully understood in terms of two dimensions of mania and depression, which have distinct personality correlates.

  15. ACUTE SYMPTOMS AND COMPLICATIONS OF HEMODIALYSIS

    Directory of Open Access Journals (Sweden)

    Bárbara Paula Magalhães de Deus

    2015-07-01

    Full Text Available Backgound and Objectives: Chronic Kidney Disease and the number of patients on renal replacement therapies have become more frequent in recent decades. Even with new technologies used in hemodialysis, which result in greater patient safety, acute symptoms and complications after the procedure may still occur. Recognizing these complications and knowing how to manage them is crucial to ensure a better quality of life for these patients. Content: This is a literature search on symptoms related to hemodialysis, carried out in electronic databases: Periodicals CAPES (Coordination of Higher Education Personnel Training, Brazil, Scientific Electronic Library Online - SciELO, LILACS and Pubmed, from which 30 articles were selected on the main complications observed and described during the course of hemodialysis. Conclusion: There was a prevalence of symptoms related to fluid and electrolyte imbalance and hemodynamic changes, especially headache. KEYWORDS: Renal Insufficiency Chronic; Symptoms; Renal Dialysis.

  16. Multiple somatic symptoms in primary care

    DEFF Research Database (Denmark)

    Goldberg, D. P.; Reed, G. M.; Robles, R.

    2016-01-01

    Objective A World Health Organization (WHO) field study conducted in five countries assessed proposals for Bodily Stress Syndrome (BSS) and Health Anxiety (HA) for the Primary Health Care Version of ICD-11. BSS requires multiple somatic symptoms not caused by known physical pathology and associated...... with BSS or HA, 70.4% were identified as having both conditions. Participants had an average of 10.9 somatic symptoms. Patients who presented somatic symptoms across multiple body systems were more disabled than patients with symptoms in a single system. Most referred patients (78.9%) had co...... without identifiable physical pathology. Although highly co-occurring with each other and with mood and anxiety disorders, BSS and HA represent distinct constructs that correspond to important presentations in primary care. © 2016 Elsevier Inc....

  17. Assessment of Menopausal Symptoms During Perimenopause and ...

    African Journals Online (AJOL)

    Menopause Rating Scale (MRS) is an effective tool to assess the severity of these symptoms. ..... lifestyle, smoking, and their attitude towards menopause also affect the ..... this article:***. Source of Support: Nil, Conflict of Interest: None declared.

  18. Symptoms and Causes of Irritable Bowel Syndrome

    Science.gov (United States)

    ... of sugars or bile acids may cause symptoms. Mental Health Problems Psychological, or mental health, problems such ... Blood Diseases Diagnostic Tests La información de la salud en español Health Statistics Healthy Moments Radio Broadcast ...

  19. Cranial Autonomic Symptoms in Pediatric Migraine

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2013-09-01

    Full Text Available Investigators at the University of California, San Francisco, examined the frequency of cranial autonomic symptoms in all pediatric and adolescent patients with migraine seen in 4 different clinical settings during July 2010 to June 2012.

  20. [Treatment of multiple sclerosis symptoms and exacerbations].

    Science.gov (United States)

    Prieto González, José María

    2014-12-01

    In the last few years, there has been an explosion of new drugs acting on the clinical course of multiple sclerosis (MS) but less attention has been paid to better knowledge of the symptoms of this disease and their pathogenesis and treatment, which is essential to improve patients' quality of life. Because many patients have numerous concurrent symptoms during their clinical course, their management is complex and consequently it is important to know which symptoms are a direct result of the degenerative lesions of MS. The present article describes all the therapeutic options available for spasticity and its associated pain, paroxystic symptoms, fatigue, genitourinary disorders and sexual dysfunction, tremor, ataxia, gait disorder and cognitive impairment, with special emphasis on novel treatments. The article also defines exacerbations, how to recognize them and the available treatments, mainly oral administration of high-dose methylprednisolone and plasmapheresis. Copyright © 2014 Elsevier España, S.L.U. All rights reserved.

  1. Retrospective assessment of seasonal allergic symptoms

    DEFF Research Database (Denmark)

    Bødtger, Uffe; Poulsen, L K; Malling, H-J

    2003-01-01

    BACKGROUND: The history of the severity of seasonal allergic symptoms is often obtained post-seasonally as a retrospective assessment. Correct rating is essential when determining the efficacy of pharmaceutical treatment, indications for allergen-specific immunotherapy (SIT), or inclusion...... into controlled clinical studies. OBJECTIVES: To investigate the agreement between in- and post-seasonal ratings of seasonal symptoms, and to investigate whether the effect of SIT could be detected retrospectively. MATERIAL AND METHODS: Thirty-five birch pollen-allergic patients were allocated to SIT or placebo...... in a double-blind study. Assessment of severity of symptoms from the nose, eyes and lungs were performed daily during the season 2000, and post-seasonally 6 months after the season in 1999 and 2000. A four-point verbal descriptor scale (VDS-4) was used at all occasions. A mean in-seasonal symptom rating...

  2. Prostate Cancer: Symptoms, Tests, and Treatment

    Science.gov (United States)

    ... Devices Radiation-Emitting Products Vaccines, Blood & Biologics Animal & Veterinary Cosmetics Tobacco Products For Consumers Home For Consumers Consumer Updates Prostate Cancer: Symptoms, Tests, and Treatment Share Tweet Linkedin Pin it ...

  3. Associations between depressive symptoms and insulin resistance

    DEFF Research Database (Denmark)

    Adriaanse, M C; Dekker, J M; Nijpels, G

    2006-01-01

    AIMS/HYPOTHESIS: The association between depression and insulin resistance has been investigated in only a few studies, with contradictory results reported. The aim of this study was to determine whether the association between symptoms of depression and insulin resistance varies across glucose...... established type 2 diabetes mellitus. Main outcome measures were insulin resistance defined by the homeostasis model assessment for insulin resistance (HOMA-IR) and symptoms of depression using the Centre for Epidemiologic Studies Depression Scale (CES-D). RESULTS: In the total sample, we found a weak.......942). The association between depressive symptoms and insulin resistance was similar for men and women. CONCLUSIONS/INTERPRETATION: We found only weak associations between depressive symptoms and insulin resistance, which did not differ among different glucose metabolism subgroups or between men and women....

  4. Relaxation Techniques to Manage IBS Symptoms

    Science.gov (United States)

    ... the Day Art of IBS Gallery Contact Us Relaxation Techniques to Manage IBS Symptoms Details Content Last Updated: ... Topic Psychological Treatments Understanding Stress Cognitive Behavioral Therapy Relaxation Techniques for IBS You’ve been to the doctor ...

  5. Interpreting angina: symptoms along a gender continuum

    Science.gov (United States)

    Crea-Arsenio, Mary; Shannon, Harry S; Velianou, James L; Giacomini, Mita

    2016-01-01

    Background ‘Typical’ angina is often used to describe symptoms common among men, while ‘atypical’ angina is used to describe symptoms common among women, despite a higher prevalence of angina among women. This discrepancy is a source of controversy in cardiac care among women. Objectives To redefine angina by (1) qualitatively comparing angina symptoms and experiences in women and men and (2) to propose a more meaningful construct of angina that integrates a more gender-centred approach. Methods Patients were recruited between July and December 2010 from a tertiary cardiac care centre and interviewed immediately prior to their first angiogram. Symptoms were explored through in-depth semi-structured interviews, transcribed verbatim and analysed concurrently using a modified grounded theory approach. Angiographically significant disease was assessed at ≥70% stenosis of a major epicardial vessel. Results Among 31 total patients, 13 men and 14 women had angiograpically significant CAD. Patients describe angina symptoms according to 6 symptomatic subthemes that array along a ‘gender continuum’. Gender-specific symptoms are anchored at each end of the continuum. At the centre of the continuum, are a remarkably large number of symptoms commonly expressed by both men and women. Conclusions The ‘gender continuum’ offers new insights into angina experiences of angiography candidates. Notably, there is more overlap of shared experiences between men and women than conventionally thought. The gender continuum can help researchers and clinicians contextualise patient symptom reports, avoiding the conventional ‘typical’ versus ‘atypical’ distinction that can misrepresent gendered angina experiences. PMID:27158523

  6. A Dementia Case Presenting with Psychotic Symptoms

    Directory of Open Access Journals (Sweden)

    Osman Ozdemir

    2013-06-01

    Full Text Available Dementia is a progressive clinical syndrome in which affected areas of brain function may be affected, such as memory, language, abstract thinking, problem solving and attention. Psychotic symptoms include auditory and visual hallucinations and delusions, which usually occur in the dementia. In this paper, a dementia case presenting with psychotic symptoms is presented. [Cukurova Med J 2013; 38(3.000: 482-486

  7. Parkinson's disease and narcolepsy-like symptoms.

    Science.gov (United States)

    Ylikoski, Ari; Martikainen, Kirsti; Sarkanen, Tomi; Partinen, Markku

    2015-04-01

    Various sleep-related problems, for example, insomnia and symptoms of rapid eye movement behavior disorder (RBD), are common in patients with Parkinson's disease (PD). We studied the prevalence of symptoms of narcolepsy (NARC), hallucinations, and RBD and their association with other symptoms. Altogether, 1447 randomly selected patients with PD, aged 43-89 years, participated in a questionnaire study. A structured questionnaire with 207 items was based on the Basic Nordic Sleep Questionnaire. Questions on demographics, PD, RBD, and other issues were included. The response rate was 59.0%; of these patients, 73% had answered to all questions that were used in the analyses (N = 623). The occurrence of suspected narcolepsy (Ullanlinna Narcolepsy Scale ≥ 14 and Epworth Sleepiness Scale ≥ 11) was observed in 9.3% of the subjects (PD with NARC), RBD (REM Sleep Behavior Disorder Screening Questionnaire ≥ 6) in 39.2% of all patients with PD, and in 62.1% of those with PD and NARC. In patients with PD, hallucinations before going to bed in the evening occurred in 5.8%, hypnagogic hallucinations in 4.0%, hallucinations during night 8.3%, and hypnopompic hallucinations in 3.2%. Cataplexy symptoms occurred in 43.1% of subjects with PD and NARC. In a logistic regression analysis, PD with NARC was associated with RBD, all types of hallucinations, daytime sleepiness, fatigue, insomnia, and intense dreaming also when adjusted for age, sex, disease duration, and levodopa. Narcolepsy-like symptoms may be present in patients with PD. Symptoms of RBD were associated with symptoms of narcolepsy including symptoms of cataplexy. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. 症状要素与症状规范化%Symptom Elements and Symptom Standardization

    Institute of Scientific and Technical Information of China (English)

    王志国; 王永炎

    2012-01-01

    本文着重论述了症状要素的概念及其与症状规范化的关系,是关于症状术语规范化的思路与方法.症状要素是症状描述或症状术语中抛开部位的部分,大部分为症状的性质,多个同类症状经常含有共同的因素."要"是简要、重要,不可或缺,也就是症状中不可或缺的重要因素.症状要素分为感觉异常、功能障碍……等20余类.症状要素+解剖部位+症状清单,三者相结合将最终实现症状术语规范化.%The article mainly deals with the concept of symptom elements and the relationship with symptom standardization, and provides thoughts and methods of standardization of symptom terms. Symptom elements are description of symptoms, or the part of symptom terms that are irrelevant to diseased sites. Symptom elements provide the nature of symptoms, so symptoms of a same kind often share common elements. Elements are inseparable to symptoms, and are classified into 20 categories, such as sensory abnormality, functional obstacle. The combination of symptom elements and anatomical parts and symptom lists can achieve eventually the standardization of symptom terms.

  9. [Three patients with the same diagnosis but very different symptoms].

    Science.gov (United States)

    Knechtle, Beat; Rüst, Christoph A; Rosemann, Thomas

    2015-01-02

    We present three cases of patients with a thoracic disc herniation with misinterpretation of the initial symptoms. In a first case, pulmonary symptoms were prominent; in a second case, the patient complained of cardiac symptoms; and in a third case, the patient reported neurological symptoms. Ineffective investigation of thoracic symptoms should raise the suspicion of a thoracic disc herniation.

  10. A multivariate exploration of basic symptoms.

    Science.gov (United States)

    Rubino, I Alex; Ciani, Nicola

    2002-01-01

    Little is known about the relationship between the different categories of basic symptoms (BS). Researchers of the Bonn School have accurately described the progression from second-level BS (relatively characteristic BS) to first-rank Schneiderian symptoms. Using a multiple regression model, the present study tried to investigate which kind of dynamic deficiencies (DDs; uncharacteristic first-level BS) mostly lead to each type of second-level BS. A group of 108 patients with a DSM-III-R diagnosis of schizophrenia completed an inventory on BS, with all items in strict accordance with those of the Bonn Scale. Five dependent variables (cognitive thought disorders, cognitive perception disorders, cognitive action disorders, increased impressionability, cenesthesias) and four independent variables (DDs with direct negative symptoms, DDs with indirect negative symptoms, affective DDs, relational DDs) were considered. Among the significant findings, a widespread contribution of DDs with indirect negative symptoms to most of the dependent variables, and the special role of DDs with direct negative symptoms as a predictor of cognitive thought disorders, must be emphasized. Suggestions for further multivariate studies in the field of BS are presented.

  11. Therapeutic Yoga: Symptom Management for Multiple Sclerosis.

    Science.gov (United States)

    Rogers, Kim A; MacDonald, Megan

    2015-11-01

    Multiple sclerosis (MS) is the most common autoimmune inflammatory demyelinating disease of the central nervous system, affecting over 2.3 million people worldwide. According to the National Institute of Neurological Disorders and Stroke, the age of disease onset is typically between 20 and 40 years, with a higher incidence in women. Individuals with MS experience a wide range of symptoms, including declining physical, emotional, and psychological symptoms (e.g., fatigue, imbalance, spasticity, chronic pain, cognitive impairment, bladder and bowel dysfunction, visual and speech impairments, depression, sensory disturbance, and mobility impairment). To date, both the cause of and cure for MS remain unknown. In recent years, more individuals with MS have been pursuing alternative methods of treatment to manage symptoms of the disease, including mind-body therapies such as yoga, meditation, breathing, and relaxation techniques. It has been suggested that the practice of yoga may be a safe and effective way of managing symptoms of MS. Therefore, the purpose of this paper is to summarize the most relevant literature on exercise and mind-body modalities to treat MS symptoms and, more specifically, the benefits and potential role of yoga as an alternative treatment of symptom management for individuals with MS. The article also discusses future directions for research.

  12. Progression of motor symptoms in Parkinson's disease

    Institute of Scientific and Technical Information of China (English)

    Ruiping Xia; Zhi-Hong Mao

    2012-01-01

    Parkinson's disease (PD) is a chronic progressive neurodegenerative disease that is clinically manifested by a triad of cardinal motor symptoms - rigidity,bradykinesia and tremor - due to loss of dopaminergic neurons.The motor symptoms of PD become progressively worse as the disease advances.PD is also a heterogeneous disease since rigidity and bradykinesia are the major complaints in some patients whereas tremor is predominant in others.In recent years,many studies have investigated the progression of the hallmark symptoms over time,and the cardinal motor symptoms have different rates of progression,with the disease usually progressing faster in patients with rigidity and bradykinesia than in those with predominant tremor.The current treatment regime of dopamine-replacement therapy improves motor symptoms and alleviates disability.Increasing the dosage of dopaminergic medication is commonly used to combat the worsenirtg symptoms.However,the drug-induced involuntary body movements and motor comphcations can significantly contribute to overall disability.Further,none of the currently-available therapies can slow or halt the disease progression.Significant research efforts have been directed towards developing neuroprotective or disease-modifying agents that are intended to slow the progression.In this article,the most recent clinical studies investigating disease progression and current progress on the development of disease-modifying drug trials are reviewed.

  13. Development of a symptom assessment instrument for chronic hemodialysis patients: the Dialysis Symptom Index.

    Science.gov (United States)

    Weisbord, Steven D; Fried, Linda F; Arnold, Robert M; Rotondi, Armando J; Fine, Michael J; Levenson, David J; Switzer, Galen E

    2004-03-01

    Little is known about the prevalence, severity, or impact of symptoms in hemodialysis patients because of the lack of a validated symptom assessment instrument. We systematically developed an index to assess physical and emotional symptom burden in this patient population. We employed four steps in the generation of this index: a review of dialysis quality-of-life instruments, three focus groups, experts' content validity assessment, and test-retest reliability measurement. Seventy-five symptoms were identified. Of these, 46 appeared in > or = 4 of the instruments/focus groups and were considered for inclusion. Twelve were grouped into other symptom constructs and experts judged four of the remaining items not to be pertinent, leaving 30 items in the new index. Overall kappa statistic was 0.48+/-0.22. These steps allowed the systematic development of a 30-item symptom assessment index for hemodialysis patients. Additional reliability and validity testing is needed prior to its widespread use.

  14. Self-reported symptoms and healthcare seeking in the general population -exploring "The Symptom Iceberg"

    DEFF Research Database (Denmark)

    Elnegaard, Sandra; Andersen, Rikke Sand; Pedersen, Anette Fischer

    2015-01-01

    BACKGROUND: Research has illustrated that the decision-making process regarding healthcare seeking for symptoms is complex and associated with a variety of factors, including gender differences. Enhanced understanding of the frequency of symptoms and the healthcare seeking behaviour in the general...... population may increase our knowledge of this complex field. The primary objective of this study was to estimate the prevalence of self-reported symptoms and the proportion of individuals reporting GP contact, in a large Danish nationwide cohort. A secondary objective was to explore gender differences in GP...... of 44 different symptoms covering a wide area of alarm symptoms and non-specific frequently occurring symptoms were selected based on extensive literature search. Further, items regarding contact to the GP were included. Data on socioeconomic factors were obtained from Statistics Denmark. RESULTS...

  15. Acupuncture Alleviated the Nonmotor Symptoms of Parkinson’s Disease including Pain, Depression, and Autonomic Symptoms

    OpenAIRE

    Chifumi Iseki; Taiga Furuta; Masao Suzuki; Shingo Koyama; Keiji Suzuki; Tomoko Suzuki; Akiyo Kaneko; Tadamichi Mitsuma

    2014-01-01

    A woman started to feel intractable pain on her lower legs when she was 76. At the age of 78, she was diagnosed as having Parkinson’s disease (PD). The leg pain was suspected to be a symptom of PD after eliminating other causes. The patient also suffered from nonmotor symptoms, depression, anxiety, hot flashes, and paroxysmal sweating. Though the patient had received pharmacotherapy including levodopa for 5 years, she still suffered from the nonmotor symptoms and was referred to our departmen...

  16. Hypothyroidism:Symptoms,Diagnosis and Treatment | NIH Medlineplus the Magazine

    Science.gov (United States)

    ... of this page please turn Javascript on. Feature: Hypothyroidism Hypothyroidism: Symptoms, Diagnosis & Treatment Past Issues / Spring 2012 Table ... of its symptoms are seen in other diseases, hypothyroidism usually cannot be diagnosed based on symptoms alone. ...

  17. What Are the Signs and Symptoms of Kawasaki Disease?

    Science.gov (United States)

    ... Twitter. What Are the Signs and Symptoms of Kawasaki Disease? Major Signs and Symptoms One of the main symptoms during the early part of Kawasaki disease, called the acute phase, is fever. The ...

  18. What Are the Signs and Symptoms of Anemia?

    Science.gov (United States)

    ... Twitter. What Are the Signs and Symptoms of Anemia? The most common symptom of anemia is fatigue ( ... mild symptoms or none at all. Complications of Anemia Some people who have anemia may have arrhythmias ( ...

  19. What Are the Signs and Symptoms of Fanconi Anemia?

    Science.gov (United States)

    ... What Are the Signs and Symptoms of Fanconi Anemia? Major Signs and Symptoms Your doctor may suspect ... sisters also should be tested for the disorder. Anemia The most common symptom of all types of ...

  20. What Are the Signs and Symptoms of Aplastic Anemia?

    Science.gov (United States)

    ... What Are the Signs and Symptoms of Aplastic Anemia? Lower than normal numbers of red blood cells, ... most of the signs and symptoms of aplastic anemia. Signs and Symptoms of Low Blood Cell Counts ...

  1. What Are the Signs and Symptoms of Sarcoidosis?

    Science.gov (United States)

    ... Twitter. What Are the Signs and Symptoms of Sarcoidosis? Many people who have sarcoidosis have no signs ... symptom is more common in women than men. Sarcoidosis Signs and Symptoms The illustration shows the major ...

  2. What Are the Signs and Symptoms of Diabetic Heart Disease?

    Science.gov (United States)

    ... What Are the Signs and Symptoms of Diabetic Heart Disease? Some people who have diabetic heart disease (DHD) ... when it's given right after symptoms occur. Coronary Heart Disease A common symptom of coronary heart disease (CHD) ...

  3. What Are the Signs and Symptoms of Coronary Heart Disease?

    Science.gov (United States)

    ... What Are the Signs and Symptoms of Coronary Heart Disease? A common symptom of coronary heart disease (CHD) ... and Symptoms of Heart Problems Related to Coronary Heart Disease Some people who have CHD have no signs ...

  4. Prostatic Cyst with Bladder Outlet Obstruction Symptoms. Case Report

    African Journals Online (AJOL)

    ADMIN

    reported a series of transrectal ultrasound on 704 patients with symptoms of bladder ... pelvic pain and prostatitis-like syndrome symptoms, but can rarely result in .... International Prostate Symptom Score (IPSS) was 20, and his quality of life ...

  5. Premonitory symptoms in migraine: an electronic diary study

    DEFF Research Database (Denmark)

    Giffin, N J; Ruggiero, L; Lipton, R B

    2003-01-01

    Migraine is frequently associated with nonheadache symptoms before, during, and after the headache. Premonitory symptoms occurring before the attack have not been rigorously studied. Should these symptoms accurately predict headache, there are considerable implications for the pathophysiology...

  6. Signs and Symptoms for Hantavirus Pulmonary Syndrome (HPS)

    Science.gov (United States)

    ... page: About CDC.gov . Hantavirus Share Compartir Signs & Symptoms for Hantavirus Pulmonary Syndrome (HPS) Due to the ... urine, droppings, or saliva of infected rodents. Early Symptoms Early symptoms include fatigue, fever and muscle aches, ...

  7. Pharmacological treatment of negative symptoms in schizophrenia.

    Science.gov (United States)

    Möller, Hans-Jürgen; Czobor, Pal

    2015-10-01

    Effective treatment of negative symptoms is one of the most important unmet needs in schizophrenic disorders. Because the evidence on current psychopharmacological treatments is unclear, the authors reviewed the findings published to date by searching PubMed with the keywords negative symptoms, antipsychotics, antidepressants, glutamatergic compounds, monotherapy and add-on therapy and identifying additional articles in the reference lists of the resulting publications. The findings presented here predominantly focus on results of meta-analyses. Evidence for efficacy of current psychopharmacological medications is difficult to assess because of methodological problems and inconsistent results. In general, the second-generation antipsychotics (SGAs) do not appear to have good efficacy in negative symptoms, although some show better efficacy than first-generation antipsychotics, some of which also demonstrated efficacy in negative symptoms. Specific trials on predominant persistent negative symptoms are rare and have been performed with only a few SGAs. More often, trials on somewhat persistent negative symptoms evaluate add-on strategies to ongoing antipsychotic treatment. Such trials, mostly on modern antidepressants, have demonstrated some efficacy. Several trials with small samples have evaluated add-on treatment with glutamatergic compounds, such as the naturally occurring amino acids glycine and D-serine and new pharmacological compounds. The results are highly inconsistent, although overall efficacy results appear to be positive. The unsatisfactory and inconsistent results can be partially explained by methodological problems. These problems need to be solved in the future, and the authors propose some possible solutions. Further research is required to identify effective treatment for the negative symptoms of schizophrenia.

  8. Symptom onset in autosomal dominant Alzheimer disease

    Science.gov (United States)

    Acosta-Baena, Natalia; Aisen, Paul S.; Bird, Thomas; Danek, Adrian; Fox, Nick C.; Goate, Alison; Frommelt, Peter; Ghetti, Bernardino; Langbaum, Jessica B.S.; Lopera, Francisco; Martins, Ralph; Masters, Colin L.; Mayeux, Richard P.; McDade, Eric; Moreno, Sonia; Reiman, Eric M.; Ringman, John M.; Salloway, Steve; Schofield, Peter R.; Sperling, Reisa; Tariot, Pierre N.; Xiong, Chengjie; Morris, John C.; Bateman, Randall J.

    2014-01-01

    Objective: To identify factors influencing age at symptom onset and disease course in autosomal dominant Alzheimer disease (ADAD), and develop evidence-based criteria for predicting symptom onset in ADAD. Methods: We have collected individual-level data on ages at symptom onset and death from 387 ADAD pedigrees, compiled from 137 peer-reviewed publications, the Dominantly Inherited Alzheimer Network (DIAN) database, and 2 large kindreds of Colombian (PSEN1 E280A) and Volga German (PSEN2 N141I) ancestry. Our combined dataset includes 3,275 individuals, of whom 1,307 were affected by ADAD with known age at symptom onset. We assessed the relative contributions of several factors in influencing age at onset, including parental age at onset, age at onset by mutation type and family, and APOE genotype and sex. We additionally performed survival analysis using data on symptom onset collected from 183 ADAD mutation carriers followed longitudinally in the DIAN Study. Results: We report summary statistics on age at onset and disease course for 174 ADAD mutations, and discover strong and highly significant (p 0.38) correlations between individual age at symptom onset and predicted values based on parental age at onset and mean ages at onset by mutation type and family, which persist after controlling for APOE genotype and sex. Conclusions: Significant proportions of the observed variance in age at symptom onset in ADAD can be explained by family history and mutation type, providing empirical support for use of these data to estimate onset in clinical research. PMID:24928124

  9. Validation of a self-reported HIV symptoms list: the ISS-HIV symptoms scale.

    Science.gov (United States)

    Bucciardini, Raffaella; Pugliese, Katherina; Francisci, Daniela; Costantini, Andrea; Schiaroli, Elisabetta; Cognigni, Miriam; Tontini, Chiara; Lucattini, Stefano; Fucili, Luca; Di Gregorio, Massimiliano; Mirra, Marco; Fragola, Vincenzo; Pompili, Sara; Murri, Rita; Vella, Stefano

    2016-01-01

    To describe the development and the psychometric properties of the Istituto Superiore di Sanità-HIV symptoms scale (lSS-HIV symptoms scale). The ISS-HIV symptom scale was developed by an Italian working team including researchers, physicians and people living with HIV. The development process went through the following steps: (1) review of HIV/AIDS literature; (2) focus group; (3) pre-test analysis; (4) scale validation. The 22 symptoms of HIV-ISS symptoms scale were clustered in five factors: pain/general discomfort (7 items); depression/anxiety (4 items); emotional reaction/psychological distress (5 items); gastrointestinal discomfort (4 items); sexual discomfort (2 items). The internal consistence reliability was for all factors within the minimum accepted standard of 0.70. The results of this study provide a preliminary evidence of the reliability and validity of the ISS-HIV symptoms scale. In the new era where HIV infection has been transformed into a chronic diseases and patients are experiencing a complex range of symptoms, the ISS-HIV symptoms scale may represent an useful tool for a comprehensive symptom assessment with the advantage of being easy to fill out by patients and potentially attractive to physicians mainly because it is easy to understand and requires short time to interpret the results.

  10. Reviewing the Dissociative Symptoms in Patients With Schizophreniaand their Association With Positive and Negative Symptoms

    Science.gov (United States)

    Ghoreishi, Abolfazl; Shajari, Zahra

    2014-01-01

    Objective: The present study aimed to clarify dissociative symptoms in patients with schizophrenia and its association with negative and positive symptom of schizophrenia. Methods: Based on the 4th edition of Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria, 80 schizophrenic subjects were randomly selected from patients who referred to the clinics of psychiatry hospital in Kerman, Iran. Eighty non-schizophrenic patients were chosen as the control group. Both groups were evaluated for dissociation symptom using the Dissociative Experience Scale (DES). Positive and Negative Syndrome Scale (PANSS) score was also used in the case group for determination of positive and negative symptom of schizophrenia. Results: The prevalence of dissociation symptom was 13% and 4% among schizophrenic and control groups, respectively (p = 0.02). In addition, there was a statistical significant association between DES score and positive symptom in schizophrenia (p = 0.02). Conclusion: The association between dissociative symptom and schizophrenia was significant and dissociative symptoms were associated with positive symptoms of schizophrenia. Declaration of interest: None. PMID:24995025

  11. Endotyping early childhood asthma by quantitative symptom assessment

    DEFF Research Database (Denmark)

    Bisgaard, Hans; Pipper, Christian Bressen; Bønnelykke, Klaus

    2011-01-01

    Asthmatic symptoms in young children reflect a heterogeneous group of diseases. Symptoms remain the primary end-point in both research and clinical management, but there is a need for standardized symptom assessment.......Asthmatic symptoms in young children reflect a heterogeneous group of diseases. Symptoms remain the primary end-point in both research and clinical management, but there is a need for standardized symptom assessment....

  12. Appraisal, coping, health status, and psychological symptoms.

    Science.gov (United States)

    Folkman, S; Lazarus, R S; Gruen, R J; DeLongis, A

    1986-03-01

    In this study we examined the relation between personality factors (mastery and interpersonal trust), primary appraisal (the stakes a person has in a stressful encounter), secondary appraisal (options for coping), eight forms of problem- and emotion-focused coping, and somatic health status and psychological symptoms in a sample of 150 community-residing adults. Appraisal and coping processes should be characterized by a moderate degree of stability across stressful encounters for them to have an effect on somatic health status and psychological symptoms. These processes were assessed in five different stressful situations that subjects experienced in their day-to-day lives. Certain processes (e.g., secondary appraisal) were highly variable, whereas others (e.g., emotion-focused forms of coping) were moderately stable. We entered mastery and interpersonal trust, and primary appraisal and coping variables (aggregated over five occasions), into regression analyses of somatic health status and psychological symptoms. The variables did not explain a significant amount of the variance in somatic health status, but they did explain a significant amount of the variance in psychological symptoms. The pattern of relations indicated that certain variables were positively associated and others negatively associated with symptoms.

  13. Symptoms of craniomandibular disorder among elderly people.

    Science.gov (United States)

    Ow, R K; Loh, T; Neo, J; Khoo, J

    1995-06-01

    This study investigated the subjective symptoms of craniomandibular disorder and the restriction in maximal mandibular opening of 891 elderly Singaporean citizens. A distribution of 22% of subjects (20% of the women and 26% of the men) reported subjective symptoms of craniomandibular disorders. The most common single symptom reported was occasional to frequent clicking sounds from the temporomandibular joints (in 15% of subjects). The other single symptoms were reported only occasionally in 2-6% of subjects. Nineteen per cent of the subjects had some restriction in maximal interincisal opening (30-39 mm) and about 1% of subjects were severely restricted in maximal opening (less than 30 mm). Subjectively evaluated limitation of wide mandibular opening was recorded for only 2% of the subjects. Background factors included general musculo-skeletal problems (54%), perceived fair to poor general health (29%), headaches (33%), work-related stress (24%), oral parafunctional clenching (4%) and grinding activity (4%). This paper confirms earlier reports that the subjective signs and symptoms of craniomandibular disorder tend to diminish in elderly people.

  14. Symptom overlap in anxiety and multiple sclerosis.

    LENUS (Irish Health Repository)

    O Donnchadha, Seán

    2013-02-14

    BACKGROUND: The validity of self-rated anxiety inventories in people with multiple sclerosis (pwMS) is unclear. However, the appropriateness of self-reported depression scales has been widely examined. Given somatic symptom overlap between depression and MS, research emphasises caution when using such scales. OBJECTIVE: This study evaluates symptom overlap between anxiety and MS in a group of 33 individuals with MS, using the Beck Anxiety Inventory (BAI). METHODS: Participants underwent a neurological examination and completed the BAI. RESULTS: A novel procedure using hierarchical cluster analysis revealed three distinct symptom clusters. Cluster one (\\'wobbliness\\' and \\'unsteady\\') grouped separately from all other BAI items. These symptoms are well-recognised MS-related symptoms and we question whether their endorsement in pwMS can be considered to reflect anxiety. A modified 19-item BAI (mBAI) was created which excludes cluster one items. This removal reduced the number of MS participants considered \\'anxious\\' by 21.21% (low threshold) and altered the level of anxiety severity for a further 27.27%. CONCLUSION: Based on these data, it is suggested that, as with depression measures, researchers and clinicians should exercise caution when using brief screening measures for anxiety in pwMS.

  15. Time series models of symptoms in schizophrenia.

    Science.gov (United States)

    Tschacher, Wolfgang; Kupper, Zeno

    2002-12-15

    The symptom courses of 84 schizophrenia patients (mean age: 24.4 years; mean previous admissions: 1.3; 64% males) of a community-based acute ward were examined to identify dynamic patterns of symptoms and to investigate the relation between these patterns and treatment outcome. The symptoms were monitored by systematic daily staff ratings using a scale composed of three factors: psychoticity, excitement, and withdrawal. Patients showed moderate to high symptomatic improvement documented by effect size measures. Each of the 84 symptom trajectories was analyzed by time series methods using vector autoregression (VAR) that models the day-to-day interrelations between symptom factors. Multiple and stepwise regression analyses were then performed on the basis of the VAR models. Two VAR parameters were found to be associated significantly with favorable outcome in this exploratory study: 'withdrawal preceding a reduction of psychoticity' as well as 'excitement preceding an increase of withdrawal'. The findings were interpreted as generating hypotheses about how patients cope with psychotic episodes.

  16. Hypercalciuria in children with urinary tract symptoms

    Directory of Open Access Journals (Sweden)

    Fallahzadeh M

    2010-01-01

    Full Text Available We performed this prospective study to determine the urinary calcium to creatinine ratio (Ca/Cr in children with different urinary symptoms. We studied 523 children in our neph-rology clinic with an age range of 3 to 14 years (mean= 8 and male to female ratio of 0.61. All the children had at least one of the urinary tract symptoms (dysuria, frequency, urgency, abdo-minal and/or flank pain, diurnal incontinence or enuresis, microscopic hematuria, urinary tract infection or urolithiasis. Fasting urine was collected for measuring calcium and creatinine and the results were compared to the values for the normal Iranian children. Ca/Cr ratio of more than 0.2 (mg/mg was considered as hypercalciuria. Of all the patients, 166 (31.3% were hypercalciuric. Urine Ca/Cr ratio was significantly higher in all the subgroups with one or more of the urinary symptoms (P< 0.001. We conclude that urine Ca/Cr ratio is significantly increased in children with all types of urinary symptoms. We recommend measuring urinary calcium in all children with urinary tract symptoms, especially if unexplained.

  17. 'Postconcussive' symptoms in persons with chronic pain.

    Science.gov (United States)

    Iverson, G L; McCracken, L M

    1997-11-01

    The purpose of this study was to examine the base rate of cognitive and neurobehavioural complaints in patients with chronic pain (N = 170) who had not sustained a head injury. The patients completed a packet of questionnaires that contained numerous questions regarding physical, cognitive, and psychological symptoms. The 'postconcussive-like' symptoms were selected and analysed. Specific symptom endorsement rates ranged from 5% to 76.5%. Disturbed sleep, fatigue, and irritability were reported by the majority of chronic pain patients. Cognitive complaints relating to forgetfulness (29%), difficulty maintaining attention (18%), and difficulty with concentration or thinking (16.5%) were endorsed by a significant minority of patients. Most patients (80.6%) endorsed three or more symptoms from Category C of the DSM-IV Postconcussional Disorder research criteria. This study further illustrates that postconcussive-like symptoms are not unique sequelae of mild head injury, and the presence of chronic pain should be considered when interpreting patients' physical, cognitive, and psychological complaints following closed head injury.

  18. Presenting symptoms of children with cancer

    DEFF Research Database (Denmark)

    Ahrensberg, Jette Møller; Hansen, Rikke Pilegaard; Olesen, Frede

    2012-01-01

    Almen praksis er involveret i det diagnostiske forløb hos 4 ud af 5 børn med kræft. De hyppigste symptomer er smerte, en knude/en hævelse og træthed. Disse tre symptomer ses hos 20-25 % af alle børn med kræft. Bleghed, feber, hovedpine og opkast ses hos mellem 10-15 % af børn med kræft. Klassiske...... hos 5 % af de børn, der fik konstateret knoglekræft. Vha et spørgeskema til praktiserende læger indsamledes data om symptomer, der sås i almen praksis og lægens tolkning af symptomerne. Symptomerne klassificeredes efter ICPC-2. Viden om symptomer og kliniske fund hos børn med kræft i almen praksis er...... relevant i forbindelse med uddannelse af alment praktiserende læger og udviklingen af kliniske retningslinjer, herunder kræftpakke for børnekræft. Den lave forekomst af alarmsymptomer har mulig indflydelse på tiden fra symptom præsentation i almen praksis til diagnose....

  19. [Negative symptoms of schizophrenia: historical aspects].

    Science.gov (United States)

    Pringuey, D; Paquin, N; Cherikh, F; Giordana, B; Belzeaux, R; Cermolacce, M; Adida, M; Azorin, J-M

    2015-12-01

    The history of negative symptoms of schizophrenia rises early days of medicine in clinical and pathophysiological differences between positive and negative and their complex joint. Forming a set of typical core of symptoms, and some feature of a syndrome belonging to a specific pathophysiological mechanism, negative symptoms of schizophrenia emerge from old descriptions of clinical pictures, related to the overall look of madness, the heart of alienation, a central sign of early dementia, gradually more precisely describing the strange nature of the autistic withdrawal and schizophrenic apragmatism. At therapeutic era, negative symptoms have taken over the positive symptoms to establish an operational criteria whose importance lies in the progressive severity of this clinical type and in their contribution to therapeutic resistance. Despite the efforts of modern typological classifications, this work rehabilitates the old concept of "unitary psychosis" by defining a common symptomatic core to multiple clinical forms of psychosis, combining deficit of emotional expression and avolition, meaning a native psychopathology and a pathophysiology possibly in a common final way, and calling the arrival of new treatment strategies. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  20. Depressive symptoms in institutionalized older adults

    Directory of Open Access Journals (Sweden)

    Lívia Maria Santiago

    2014-04-01

    Full Text Available OBJECTIVE To estimate the prevalence of depressive symptoms among institutionalized elderly individuals and to analyze factors associated with this condition. METHODS This was a cross-sectional study involving 462 individuals aged 60 or older, residents in long stay institutions in four Brazilian municipalities. The dependent variable was assessed using the 15-item Geriatric Depression Scale. Poisson’s regression was used to evaluate associations with co-variables. We investigated which variables were most relevant in terms of presence of depressive symptoms within the studied context through factor analysis. RESULTS Prevalence of depressive symptoms was 48.7%. The variables associated with depressive symptoms were: regular/bad/very bad self-rated health; comorbidities; hospitalizations; and lack of friends in the institution. Five components accounted for 49.2% of total variance of the sample: functioning, social support, sensory deficiency, institutionalization and health conditions. In the factor analysis, functionality and social support were the components which explained a large part of observed variance. CONCLUSIONS A high prevalence of depressive symptoms, with significant variation in distribution, was observed. Such results emphasize the importance of health conditions and functioning for institutionalized older individuals developing depression. They also point to the importance of providing opportunities for interaction among institutionalized individuals.

  1. Renal provider recognition of symptoms in patients on maintenance hemodialysis.

    Science.gov (United States)

    Weisbord, Steven D; Fried, Linda F; Mor, Maria K; Resnick, Abby L; Unruh, Mark L; Palevsky, Paul M; Levenson, David J; Cooksey, Stephen H; Fine, Michael J; Kimmel, Paul L; Arnold, Robert M

    2007-09-01

    Although several studies have found that the burden of symptoms in patients who are on maintenance hemodialysis is substantial, little is known about renal providers' awareness of these symptoms. The aim of this study was to assess renal provider recognition of symptoms and their severity in hemodialysis patients. The Dialysis Symptom Index, a 30-item measure of symptoms and their severity, was administered to patients during a routine hemodialysis session. Immediately after surveying patients, the renal provider who evaluated the patient completed the Dialysis Symptom Index to report the symptoms that he or she believed were present in that patient. Sensitivity, specificity, and positive and negative predictive values of provider reports of symptoms were calculated using patient reports as the reference standard. Patient-provider agreement on the presence and severity of symptoms was assessed using the kappa statistic. Surveys were completed by 75 patients and 18 providers. For 27 of 30 symptoms, the sensitivity of provider responses was <50%, and provider responses for 25 symptoms were characterized by positive predictive values of <75%. kappa scores for 25 symptoms including those pertaining to pain, sexual dysfunction, sleep disturbance, and psychologic distress were <0.20, indicating poor provider recognition of these symptoms. Providers underestimated the severity of 19 of 30 symptoms. Renal providers are largely unaware of the presence and severity of symptoms in patients who are on maintenance hemodialysis. Implementation of a standardized symptom assessment process may improve provider recognition of symptoms and promote use of symptom-alleviating treatments.

  2. What Are the Signs and Symptoms of Pneumonia?

    Science.gov (United States)

    ... Home » Health Information for the Public » Health Topics » Pneumonia » Signs, Symptoms, and Complications Explore Pneumonia Pneumonia Causes Risk Factors Signs, Symptoms, and Complications ...

  3. Methylphenidate-induced mania-like symptoms

    Directory of Open Access Journals (Sweden)

    Kaustav Chakraborty

    2011-01-01

    Full Text Available Therapeutic dose of methylphenidate is known to cause adverse effects (psychosis or mania, albeit in a small number of cases. Signs and symptoms of adverse effects usually disappear on stopping the medicine. Data regarding the safety of methylphenidate in comorbid attention deficit hyperactivity disorder (ADHD and mental retardation are nonexistent. We describe a case of an 11-year-old girl with ADHD and mental retardation treated with methylphenidate, who developed mania like symptoms requiring inpatient treatment. The index case required psychopharmacological intervention with sodium valproate and olanzapine as the symptoms did not subside even after 3 days. This case highlights the fact that one has to exercise caution while prescribing methylphenidate in patients with comorbid ADHD and mental retardation.

  4. Transient Neurological Symptoms after Spinal Anesthesia

    Directory of Open Access Journals (Sweden)

    Zehra Hatipoglu

    2013-02-01

    Full Text Available Lidocaine has been used for more than 50 years for spinal anesthesia and has a remarkable safety record. In 1993, a new adverse effect, transient neurologic toxicity was described in patients recovering from spinal anesthesia with lidocaine. Transient neurological symptoms have been defined as pain in the lower extremities (buttocks, thighs and legs after an uncomplicated spinal anesthesia and after an initial full recovery during the immediate postoperative period (less than 24 h. The incidence of transient neurological symptoms reported in prospective, randomized trials varies from 4% to 37%. The etiology of transient neurological symptoms remains unkonwn. Despite the transient nature of this syndrome, it has proven to be difficult to treat effectively. Drug or some interventional therapy may be necessary. [Archives Medical Review Journal 2013; 22(1.000: 33-44

  5. [Validity of assessment of schizophrenic basic symptoms].

    Science.gov (United States)

    Mass, R; Hitschfeld, K; Wall, E; Wagner, H B

    1997-03-01

    A study on the concept and measurement of the basic disorders of schizophrenia is presented. A total of 151 male adult psychiatric inpatients (51 with a dual diagnosis of schizophrenia and alcoholism, 50 schizophrenics and 50 alcoholics) were included. The aims of this study were: (1) the replication of the previous finding that the Frankfurt Complaint Questionnaire (FBF) contains items that discriminate between schizophrenia and alcoholism; (2) an empirical comparison between FBF and the Bonn Scale for the Assessment of Basic Symptoms (BSABS); (3) testing the relationship between basic and negative versus positive symptoms, as measured by the Positive and Negative Syndrome Scale (PANSS). Regarding (1), the former result was replicated. Regarding (2), FBF subscales and BSABS categories were shown to be significantly but weakly related, even if identical symptoms were included in the inquiry. Regarding (3), FBF and BSABS were found to be more closely related to negative than to positive PANSS items. Theoretical implications and consequences for further research are discussed.

  6. Depersonalization and basic symptoms in schizophrenia.

    Science.gov (United States)

    Maggini, Carlo; Raballo, Andrea; Salvatore, Paola

    2002-01-01

    The purpose of this study is to examine the classic psychopathologic notion of depersonalization in the light of the Basic Symptom paradigm. A sample of 57 chronic schizophrenics was cross-sectionally assessed with the Bonn Scale for the Assessment of Basic Symptoms (BSABS) and contextually with specific scales testing positive, negative, depressive and alexithymic dimensions. In order to categorize depersonalized vs. nondepersonalized patients three specific BSABS items explicitly identifying the allo-/auto-/somatopsychic domains of depersonalization were used, according to the wernickian threefold definition. Depersonalized schizophrenics showed a semiological profile that was distinct from that of nondepersonalized schizophrenics (as regards basic, positive, depressive symptoms and alexithymia); patients with multiple co-occurring forms of depersonalization revealed higher levels of cognitive disturbance, lowering of stress threshold and greater alexithymia. Clinical and research implications are discussed.

  7. [Negative symptoms in schizophrenia: new pharmacological approaches].

    Science.gov (United States)

    Lodovighi, M-A; Palomba, A; Belzeaux, R; Adida, M; Azorin, J-M

    2015-12-01

    The management of negative symptoms appears to be a major challenge because of functional disability induced by these symptoms and their relative resistance to treatments currently on the market. The aim of this article is to review new approaches that may enable optimal management of these symptoms. First, we describe the methodological difficulties that hindered the development and evaluation of specific treatment, and objectives currently defined to enable the development of new pharmacological approaches. Then we present the monotherapy and adjuvant therapies that have been assessed, including first and second generation antipsychotics, psychostimulants, antidepressants, cholinergic and glutamatergic agents, the oxytocin, hormones and more invasive therapies such as transcranial magnetic stimulation (rTMS) and electroconvulsive therapy (ECT). Other molecules are under development and evaluation such alpha-7 nicotinic receptor agonists.

  8. Initial symptoms and clinical features in osteosarcoma

    Institute of Scientific and Technical Information of China (English)

    Sujia Wu; Xing Shi; Jianling Zhao; Yurong Wang; Jun Zhang; Liwu Zhou; Yuexian Cheng; Guangxin Zhou

    2005-01-01

    Objective: To establish the initial symptoms and physical signs of osteosarcoma from the records of the first medical visit and to identify early characteristics of the diseases to shorten the delay of diagnosis. Methods: A group of patients with osteosarcoma in extremities was identified from Nanjing Jinling Hospital. Records from the first medical visit due to symptoms and physical signs related to the bone tumor were obtained from 71 patients with osteosarcoma. Results: The results of the data recorded about the first medical visit,reasons for consultation, pain,trauma,initial diagnosis,delay in diagnosis were reported respectively. Conclusion: Pair an initial symptom of osteosarcoma, and was intermittent but not frequently felt at night. A history of trauma was common, but the clinical course often diverged from what was expected from trauma. The most important clinical feature was a palpable mass. This finding emphasizes that a thorough physical examination is absolutely necessary.

  9. Anxiety symptoms in HIV-infected individuals.

    Science.gov (United States)

    Kemppainen, Jeanne K; MacKain, Sally; Reyes, Darcel

    2013-01-01

    Anxiety is one of the most frequent symptoms recognized by providers who care for persons living with HIV disease (PLWH). This evidence-based review of anxiety and HIV disease includes an overview of anxiety symptoms, their prevalence in PLWH, and co-existing mood and behavioral disorders. Harmful physiologic effects are also highlighted. Valid and reliable clinical measurement tools used for assessing anxiety include the Clinical Diagnostic Questionnaire, the Hamilton Anxiety Scale, the State-Trait Anxiety Scale, the Profile of Mood States, and the Hospital Anxiety and Depression Scale. Evidence supports the use of cognitive behavioral therapy as a recommended intervention for the treatment of anxiety symptoms and/or anxiety disorders in PLWH. Medications for use with more severe and disabling anxiety are discussed, as well as evidence based on expert opinion for anxiety self-management.

  10. Behavioral and Psychological Symptoms of Dementia

    Directory of Open Access Journals (Sweden)

    Joaquim eCerejeira

    2012-05-01

    Full Text Available Behavioral and psychological symptoms of dementia (BPSD, also known as neuropsychiatric symptoms, represent a heterogeneous group of non-cognitive symptoms and behaviors occurring in subjects with dementia. BPSD constitute a major component of the dementia syndrome irrespective of its subtype. They are as clinically relevant as cognitive symptoms as they strongly correlate with the degree of functional and cognitive impairment. BPSD include agitation, aberrant motor behavior, anxiety, elation, irritability, depression, apathy, disinhibition, delusions, hallucinations, and sleep or appetite changes. It is estimated that BPSD affect up to 90% of all dementia subjects over the course of their illness, and is independently associated with poor outcomes, including distress among patients and caregivers, long term hospitalization, misuse of medication and increased health care costs. Although these symptoms can be present individually it is more common that various psychopathological features co-occur simultaneously in the same patient. Thus, categorization of BPSD in clusters taking into account their natural course, prognosis and treatment response may be useful in the clinical practice. The pathogenesis of BPSD has not been clearly delineated but it is probably the result of a complex interplay of psychological, social and biological factors. Recent studies have emphasized the role of neurochemical, neuropathological and genetic factors underlying the clinical manifestations of BPSD. A high degree of clinical expertise is crucial to appropriately recognize and manage the neuropsychiatric symptoms in a patient with dementia. Combination of non-pharmacological and careful use of pharmacological interventions is the recommended therapeutic for managing BPSD. Given the modest efficacy of current strategies, there is an urgent need to identify novel pharmacological targets and develop new non-pharmacological approaches to improve the adverse outcomes

  11. The cultural shaping of depression: somatic symptoms in China, psychological symptoms in North America?

    Science.gov (United States)

    Ryder, Andrew G; Yang, Jian; Zhu, Xiongzhao; Yao, Shuqiao; Yi, Jinyao; Heine, Steven J; Bagby, R Michael

    2008-05-01

    The expectation that Chinese people present distress somatically is a central prediction of cultural psychopathology and has been the subject of considerable theoretical speculation. At the same time, empirical studies have been infrequent and have yielded mixed results. The authors examined symptom presentation in Chinese (n=175) and Euro-Canadian (n=107) outpatients, using spontaneous problem report, structured clinical interview, and symptom questionnaire methods. All 3 methods yielded cross-culturally equivalent somatic and psychological symptom subscales. Chinese outpatients reported more somatic symptoms on spontaneous problem report and structured clinical interview compared with Euro-Canadians, who in turn reported more psychological symptoms on all 3 methods. The relation between culture and somatic symptom presentation was mediated by a tendency toward externally oriented thinking. Difficulties with identifying emotions or describing them to others did not differ significantly across cultures, supporting a nonpathological interpretation of observed differences. Psychological symptom effects were larger and more consistent than somatic symptom effects; because other studies have confirmed the ubiquity of somatic presentations worldwide, these results suggest that Western psychologization may be more culturally specific than is Chinese somatization.

  12. Symptom scoring systems to diagnose distal polyneuropathy in diabetes : the Diabetic Neuropathy Symptom score

    NARCIS (Netherlands)

    Meijer, J.W.G.; Smit, A.J.; van Sonderen, E.; Groothoff, J.W.; Eisma, W.H.; Links, T.P.

    2002-01-01

    AIMS: To provide one of the diagnostic categories for distal diabetic polyneuro-pathy,several symptom scoring systems are available, which are often extensive andlack in validation. We validated a new four-item Diabetic Neuropathy Symptom (DNS) scorefor diagnosing distal diabetic polyneuropathy. MET

  13. Correlation of Visual Prostate Symptom Score with International Prostate Symptom Score and Uroflowmetry Parameters in Nepalese Male Patients with Lower Urinary Tract Symptoms.

    Science.gov (United States)

    Bhomi, K K; Subedi, N; Panta, P P

    2017-01-01

    International prostate symptom score is a validated questionnaire used to evaluate the lower urinary tract symptoms in benign prostatic hyperplasia. Visual prostate symptom score is a new simplified symptom score with pictograms to evaluate the same. We evaluated the correlation of visual prostate symptom score with international prostate symptom score and uroflowmetry parameters in Nepalese male patients with lower urinary tract symptoms. Male patients aged ≥40 years attending the Urology clinic were enrolled in the study. They were given international prostate symptom score and visual prostate symptom score questionnaires to complete providing assistance whenever needed. Demographic data, examination findings and uroflowmetry parameters were noted. Correlation and regression analysis was used to identify correlation of the two scoring systems and uroflowmetry parameters. Among the 66 patients enrolled, only 10 (15.15%) patients were able to understand English language. There was a statistically significant correlation between total visual prostate symptom score and international prostate symptom score (r= 0.822; Pcorrelations between individual scores of the two scoring systems related to force of urinary stream, frequency, nocturia and quality of life were also statistically significant. There was also a statistically significant correlation of both scores with maximum flow rate and average flow rate. There is a statistically significant correlation of visual prostate symptom score with international prostate symptom score and uroflowmetry parameters. IPSS can be replaced with simple VPSS in evaluation of lower urinary tract symptoms in elderly male patients.

  14. Symptom removal: the nineteenth century experience.

    Science.gov (United States)

    Weitzenhoffer, Andre

    2002-10-01

    It has been said that traditional clinical hypnotists, essentially those practicing before 1900, made excessive use of symptom removal to the detriment of their patients. However, statements of this kind have never been documented. This article is based on a search of the relevant literature that examines the hypnotic methods and results of that era. One finding is that available clinical data support the claim that clinical hypnotists practicing before 1900 made considerable use of symptom removal. The data also indicate that they achieved substantial success without any detrimental effects. This information is considered relevant for the scientifically based practice of hypnosis.

  15. Parental recognition of postconcussive symptoms in children.

    Science.gov (United States)

    Stevens, Penelope K; Penprase, Barbara; Kepros, John P; Dunneback, James

    2010-01-01

    Evaluation of current emergency department discharge instructions and parental recognition of symptomatology requiring further care for traumatic brain injury (TBI) is not well understood. A convenience sample of 105 parents of children aged 5 to 17 years who were seen and discharged from the pediatric emergency department with TBI was identified. Parents were surveyed by telephone 2 to 5 days after injury and a questionnaire was completed regarding identification of TBI symptoms. This study demonstrated that despite verbal and written discharge instructions, many parents with symptomatic children reported that their children were asymptomatic, and unable to identify postconcussive symptoms in their children.

  16. Nasal chondromesenchymal hamartoma with no nasal symptoms.

    LENUS (Irish Health Repository)

    Uzomefuna, Vincent

    2012-01-01

    The authors present a case of nasal chondromesenchymal hamartoma (NCMH) in an 8-year-old boy with a 4-month history of frontal headache and no symptoms of nasal obstruction, rhinorrhoea or postnasal drip. An ENT examination as well as ophthalmology assessment presented normal results. CT scan showed a lesion involving the sphenoid and ethmoid sinuses. The patient had an endoscopic resection of the lesion that was confirmed histologically to be a NCMH. Though NCMH is known to present usually in infants with obstructing nasal mass, an unusual presentation of a patient with throbbing headache without any nasal symptoms is reported here.

  17. Self-compassion and PTSD symptom severity.

    Science.gov (United States)

    Thompson, Brian L; Waltz, Jennifer

    2008-12-01

    Neff's (2003a, 2003b) notion of self-compassion emphasizes kindness towards one's self, a feeling of connectedness with others, and mindful awareness of distressing experiences. Because exposure to trauma and subsequent posttraumatic stress symptoms (PSS) may be associated with self-criticism and avoidance of internal experiences, the authors examined the relationship between self-compassion and PSS. Out of a sample of 210 university students, 100 endorsed experiencing a Criterion A trauma. Avoidance symptoms significantly correlated with self-compassion, but reexperiencing and hyperarousal did not. Individuals high in self-compassion may engage in less avoidance strategies following trauma exposure, allowing for a natural exposure process.

  18. The range of symptoms in refugees of war: the New Mexico Refugee Symptom Checklist-121.

    Science.gov (United States)

    Hollifield, Michael; Warner, Teddy D; Krakow, Barry; Jenkins, Janis; Westermeyer, Joseph

    2009-02-01

    The range of symptoms experienced by refugees of war has not been empirically assessed. The New Mexico Refugee Symptom Checklist-121 (NMRSCL-121) was developed utilizing established guidelines and evaluated for its psychometric properties. Community-dwelling Kurdish and Vietnamese refugees reported 48 (SD = 31) persistent and bothersome somatic and psychological symptoms on the NMRSCL-121. Internal consistency and test-retest reliability for the total scale and for most subscales were acceptable, and construct and concurrent validity for the NMRSCL-121 data was shown. There were modest ethnic group differences on symptom severity and psychometric properties of NMRSCL-121 subscales. The NMRSCL-121 produces reliable and valid assessments of a wide range of symptoms in 2 broad community samples of displaced adult refugees.

  19. Catatonic Symptoms Appearing before Autonomic Symptoms Help Distinguish Neuroleptic Malignant Syndrome from Malignant Catatonia.

    Science.gov (United States)

    Komatsu, Takayuki; Nomura, Tomohisa; Takami, Hiroki; Sakamoto, So; Mizuno, Keiko; Sekii, Hajime; Hatta, Kotaro; Sugita, Manabu

    A 42-year-old Japanese woman with a 10-year history of schizophrenia was admitted due to a disturbance in consciousness that met the diagnostic criteria for both neuroleptic malignant syndrome (NMS) and malignant catatonia. Despite systemic supportive treatments, the catatonic symptoms preceding autonomic symptoms persisted. The symptoms improved after lorazepam administration, leading to a retrospective diagnosis of malignant catatonia. Catatonia is thought to be caused by a dysfunction of ganmma-aminobutyric acid type A receptors in the cortico-cortical networks of the frontal lobes, which causes hypoactivity of the dopaminergic transmission in the subcortical areas. Identifying the catatonic symptoms preceding autonomic symptoms could aid in distinguishing malignant catatonia from NMS.

  20. The Autonomic Symptom Profile: a new instrument to assess autonomic symptoms

    Science.gov (United States)

    Suarez, G. A.; Opfer-Gehrking, T. L.; Offord, K. P.; Atkinson, E. J.; O'Brien, P. C.; Low, P. A.

    1999-01-01

    OBJECTIVE: To develop a new specific instrument called the Autonomic Symptom Profile to measure autonomic symptoms and test its validity. BACKGROUND: Measuring symptoms is important in the evaluation of quality of life outcomes. There is no validated, self-completed questionnaire on the symptoms of patients with autonomic disorders. METHODS: The questionnaire is 169 items concerning different aspects of autonomic symptoms. The Composite Autonomic Symptom Scale (COMPASS) with item-weighting was established; higher scores indicate more or worse symptoms. Autonomic function tests were performed to generate the Composite Autonomic Scoring Scale (CASS) and to quantify autonomic deficits. We compared the results of the COMPASS with the CASS derived from the Autonomic Reflex Screen to evaluate validity. RESULTS: The instrument was tested in 41 healthy controls (mean age 46.6 years), 33 patients with nonautonomic peripheral neuropathies (mean age 59.5 years), and 39 patients with autonomic failure (mean age 61.1 years). COMPASS scores correlated well with the CASS, demonstrating an acceptable level of content and criterion validity. The mean (+/-SD) overall COMPASS score was 9.8 (+/-9) in controls, 25.9 (+/-17.9) in the patients with nonautonomic peripheral neuropathies, and 52.3 (+/-24.2) in the autonomic failure group. Scores of symptoms of orthostatic intolerance and secretomotor dysfunction best predicted the CASS on multiple stepwise regression analysis. CONCLUSIONS: We describe a questionnaire that measures autonomic symptoms and present evidence for its validity. The instrument shows promise in assessing autonomic symptoms in clinical trials and epidemiologic studies.

  1. Improving Symptom Control in Early Parkinson's Disease

    OpenAIRE

    Isaacson, Stuart H; Hauser, Robert A.

    2009-01-01

    Motor symptoms in Parkinson's disease (PD) are caused by a severe loss of pigmented dopamine-producing nigro-striatal neurons. Symptomatic therapies provide benefit for motor features by restoring dopamine receptor stimulation. Studies have demonstrated that delaying the introduction of dopaminergic medical therapy is associated with a rapid decline in quality of life. Nonmotor s...

  2. Correlates of psychotic symptoms among elderly outpatients.

    Science.gov (United States)

    Holroyd, S; Laurie, S

    1999-05-01

    Psychotic symptoms presenting in late life can offer a diagnostic challenge to the clinician. In this study, 140 geriatric outpatients were prospectively examined for psychotic symptoms and assessed on a number of demographic and clinical variables. Cognition was assessed using the Mini-Mental State Exam. Psychiatric diagnoses were made by DSM-III-R criteria. Twenty-seven per cent (N = 38) had psychotic symptoms, delusions being the most common type. Patients with psychosis were significantly more likely to have a previous history of psychosis, to have a lower MMSE and to live in a nursing home. Four diagnoses accounted for 79.5% of all psychotic patients. In order of frequency, these were dementia, major depression, delirium and organic psychosis (organic hallucinosis, organic delusional disorder). Psychotic patients were significantly more likely to have a diagnosis of dementia, delirium or organic psychosis than non-psychotics, but depression was significantly more likely to occur in patients without psychosis. Although psychotic symptoms occur in a variety of illnesses, elderly patients with psychosis should be carefully evaluated for these disorders.

  3. Emotion Regulation and Depressive Symptoms in Preadolescence

    Science.gov (United States)

    Siener, Shannon; Kerns, Kathryn A.

    2012-01-01

    This study examined associations among several measures of emotion regulation, and their links to depressive symptoms, in a sample of children ages 10-12 years old (N = 87). Both temporal features of emotion regulation and regulation processes involved in the evaluation, monitoring, and modification of emotion were assessed through parent and…

  4. Psychiatric Symptoms in Children with Primary Headache

    Science.gov (United States)

    Anttila, Pirjo; Sourander, Andre; Metsahonkala, Liisa; Aromaa, Minna; Helenius, Hans; Sillanpaa, Matti

    2004-01-01

    Objective: To examine the association of psychiatric symptoms with migraine and tension-type headache in children. Method: A questionnaire completed by 1,135 Finnish children in the sixth grade identified 154 children with migraine, 138 with tension-type headache, and 407 children who were headache-free. Seventy children were randomly selected…

  5. Psychiatric Symptoms in Alpha-Mannosidosis

    Science.gov (United States)

    Malm, D.; Pantel, J.; Linaker, O. M.

    2005-01-01

    Alpha-mannosidosis is characterized by mild to moderate intellectual disability (ID), moderate to severe neurosensory hearing loss, frequent infections, psychomotor disturbances and skeletal dysmorphism. For the first time, a panel of nine alpha-mannosidosis patients with psychiatric symptoms is presented. The clinical picture has several…

  6. Maternal Depressive Symptoms following Autism Spectrum Diagnosis

    Science.gov (United States)

    Taylor, Julie Lounds; Warren, Zachary E.

    2012-01-01

    The current study examined depressive symptoms, concerning the week following autism spectrum diagnosis and an average of 1.4 years later, in mothers (n = 75) of young children diagnosed with an autism spectrum disorder (ASD). Over three-quarters of mothers (78.7%) provided retrospective reports of clinically significant depressive symptoms…

  7. Distress attributed to negative symptoms in schizophrenia

    NARCIS (Netherlands)

    Selten, JP; Wiersma, D; van den Bosch, RJ

    2000-01-01

    The purpose of the study was to examine (1) to which negative symptoms schizophrenia patients attribute distress and (2) whether clinical variables can predict the levels of reported distress. With the help of a research assistant, 86 hospitalized patients completed a self-rating scale for negative

  8. Anorexia Nervosa: Its Symptoms and Possible Cures.

    Science.gov (United States)

    Bingaman, David E.

    This document presents a definition and description of anorexia nervosa as a disorder that occurs predominantly in girls and that can affect 1 out of every 250 girls between the ages of 12 and 18 years. The existence of a distorted mental body image among anorexics is discussed and symptoms of the disorder are described, including amenorrhea…

  9. Onset symptoms in paediatric multiple sclerosis

    DEFF Research Database (Denmark)

    Boesen, Magnus Spangsberg; Sellebjerg, Finn; Blinkenberg, Morten

    2014-01-01

    INTRODUCTION: Paediatric multiple sclerosis (MS) carries a relatively higher mortality and morbidity than adult MS. Paediatric MS symptoms and paraclinical findings at the first demyelinating event have never before been characterised in a Danish setting. The aim of this study was to compare...

  10. THE STRUCTURE OF OBSESSIVE-COMPULSIVE SYMPTOMS

    NARCIS (Netherlands)

    VANOPPEN, P; HOEKSTRA, RJ; EMMELKAMP, PMG

    In the present study, the structure of obsessive-compulsive symptoms was investigated by means of the Padua Inventory (PI). Simultaneous Components Analysis on data from obsessive-compulsives (n = 206), patients with other anxiety disorders (n = 222), and a non clinical sample (n = 430) revealed a

  11. Huge Pericardial Cyst Misleading Symptoms of COPD

    Directory of Open Access Journals (Sweden)

    Göktürk Fındık

    2012-04-01

    Full Text Available Pericardial cysts are rare benign congenital mediastinal lesions. It accounts 30% of all mediastinal cysts. They are usually asemptomatic. They can produce the compression of the mediastinal structures typically caused the symptoms of dyspnea, thoracic pain, tachicardia and cough due to the unusual large size of the cyst. It can performed symptoms of lung atelectasia. The case was a sixty-five years old woman followed with a diagnosis of COPD for seven years. The patient was admitted to our center with the diagnosis of elevation of the right hemidiaphragm on chest radiography. The computed tomography revealed a cystic lesion adjacent to the right hemidiaphragm and cyst excision was performed via right thoracotomy. Patient%u2019s postoperative clinical findings indicated that the symptoms of COPD regressed completely and the patient did not require any further bronchodilator therapy. The aim of this case report is to demonstrate that the pericardial cysts can be missed in chest radiographs and impression of cysts may cause COPD like symptoms in these patients.

  12. Sickness absence due to depressive symptoms

    NARCIS (Netherlands)

    Koopmans, P. C.; Roelen, C. A. M.; Groothoff, J. W.

    Objective There is no information on the duration of absence of depressed Dutch workers. The aim of this study was to determine the duration of sickness absence due to depressive symptoms in the working population. Methods In this observational study of 15% of the Dutch working population, all

  13. Symptom removal: the twentieth century experience.

    Science.gov (United States)

    Weitzenhoffer, André M

    2004-01-01

    The twentieth century hypnosis literature regarding the use of direct symptom removal with hypnosis is in strong contrast with that of the nineteenth. It shows much ambivalence about the use of symptom removal. Objections, largely based on conclusions drawn from psychoanalytic theory, led many twentieth century psychotherapists to reject direct symptom removal. However, a certain amount of empirical evidence, scattered through the literature, has accumulated during the twentieth century to support this rejection. The lack of satisfactory twentieth century statistics and of nineteenth century details concerning hypnotic interventions that were used, makes it impossible to satisfactorily account for the discrepancy in experiences of the nineteenth and twentieth centuries. Although therapists did not altogether abandon working directly with symptoms, many opted instead for modifying and manipulating them by suggestion instead of completely removing them, usually allowing the patient to retain a psychodynamically suitable substitute. Here again a lack of adequate statistics prevents one from being able to properly appraise the effectiveness of this approach which has remained the preferred one for a number of therapists.

  14. Does Early Adolescent Sex Cause Depressive Symptoms?

    Science.gov (United States)

    Sabia, Joseph J.

    2006-01-01

    A recent study by the Heritage Foundation (Rector, Johnson, & Noyes, 2003) found evidence of a positive relationship between early sexual intercourse and depressive symptoms. This finding has been used to bolster support for funding abstinence only sex education. However, promoting abstinence will only yield mental health benefits if there is…

  15. Depression, Life Events and Somatic Symptoms.

    Science.gov (United States)

    Rozzini, Renzo; And Others

    1988-01-01

    Investigated the relationship between somatic symptoms, depression, and life events (health status, function, social satisfaction, income) in a population of 1,201 elderly persons living at home. Found depression was the most important factor in the appearance of somatic complaints; however, life events were important cofactors in defining…

  16. Patterns of depressive symptoms in epilepsy

    Directory of Open Access Journals (Sweden)

    Nikolaos I. Triantafyllou

    2013-04-01

    Full Text Available Objective: The purpose of this study was to determine the nature and extent of depressive symptoms among patients with epilepsy.Methods:Ninety patients were investigated over a three-month period: 42 were suffering from generalized epilepsy, 29 from focal epilepsy and 19 from undetermined epilepsy. All completed the Zung self-rating scale for assessment of the depressive symptoms.Results:Sixty-seven patients felt stigmatized because of epilepsy (67%: 73.6% in the undetermined epilepsy group, 55.1% in the focal epilepsy group and 88% in the generalized epilepsy group. Moreover, among the 90 epileptic patients studied, symptoms of irritability, indecisiveness, personal devaluation and emptiness showed a constant increasing trend for their presence from the undetermined epilepsy group through the generalized epilepsy group to the focal epilepsy group.Conclusions:These findings indicate that although the focal epilepsy patients felt less stigmatized, they did not differ greatly in terms of depressive symptoms, in relation to the undetermined epilepsy and generalized epilepsy patients.

  17. Neuropsychiatric symptoms in patients with thymoma- associated ...

    African Journals Online (AJOL)

    Symptoms of moderate or severe depression and anxiety were present in around 30%. ... scores and a tendency to suicidal behaviour. ... stabilised on immunosuppressive therapy and a thymectomy was ... The quantified MG score, recent thyroid studies, .... examining broader psychopathology, e.g. cognitive impairment,.

  18. Neuropsychological Correlates of Early Symptoms of Autism.

    Science.gov (United States)

    Dawson, Geraldine; Meltzoff, Andrew N.; Osterling, Julie; Rinaldi, Julie

    1998-01-01

    Examined performance on neuropsychological tests (tapping the medial temporal lobe and related limbic structures, and the dorsolateral prefrontal cortex, respectively) in relation to performance on tasks assessing autistic symptoms in young children with autism, and developmentally matched children with Down syndrome or typical development.…

  19. An integrated network model of psychotic symptoms.

    Science.gov (United States)

    Looijestijn, Jasper; Blom, Jan Dirk; Aleman, André; Hoek, Hans W; Goekoop, Rutger

    2015-12-01

    The full body of research on the nature of psychosis and its determinants indicates that a considerable number of factors are relevant to the development of hallucinations, delusions, and other positive symptoms, ranging from neurodevelopmental parameters and altered connectivity of brain regions to impaired cognitive functioning and social factors. We aimed to integrate these factors in a single mathematical model based on network theory. At the microscopic level this model explains positive symptoms of psychosis in terms of experiential equivalents of robust, high-frequency attractor states of neural networks. At the mesoscopic level it explains them in relation to global brain states, and at the macroscopic level in relation to social-network structures and dynamics. Due to the scale-free nature of biological networks, all three levels are governed by the same general laws, thereby allowing for an integrated model of biological, psychological, and social phenomena involved in the mediation of positive symptoms of psychosis. This integrated network model of psychotic symptoms (INMOPS) is described together with various possibilities for application in clinical practice.

  20. An integrated network model of psychotic symptoms

    NARCIS (Netherlands)

    Looijestijn, Jasper; Blom, Jan Dirk; Aleman, Andre; Hoek, Hans W.; Goekoop, Rutger

    2015-01-01

    The full body of research on the nature of psychosis and its determinants indicates that a considerable number of factors are relevant to the development of hallucinations, delusions, and other positive symptoms, ranging from neurodevelopmental parameters and altered connectivity of brain regions to