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Sample records for preliminary imaging experiments

  1. MR imaging of prostate. Preliminary experience with calculated imaging in 28 cases

    Energy Technology Data Exchange (ETDEWEB)

    Gevenois, P.A.; Van Regemorter, G.; Ghysels, M.; Delepaut, A.; Van Gansbeke, D.; Struyven, J.

    1988-04-01

    The majority of studies with MR imaging in prostate disease are based on a semiology obtained using images weighted in T1 and T2. A study was carried out to evaluate effects of images calculated in T1 and T2 obtained at 0.5T. This preliminary study concerns 28 prostate examinations with spin-echo acquisition and inversion-recuperation parameters, and provided images calculated in T1, weighted and calculated in T2. Images allowed detection and characterization of prostate lesions. However, although calculated images accentuate discrimination of the method, the weighted images conserve their place because of their improved spatial resolution.

  2. Fetal magnetic resonance imaging: jumping from 1.5 to 3 tesla (preliminary experience)

    Energy Technology Data Exchange (ETDEWEB)

    Victoria, Teresa [The Children' s Hospital of Philadelphia, Radiology Department, Center for Fetal Diagnosis and Treatment, Philadelphia, PA (United States); Jaramillo, Diego; Roberts, Timothy Paul Leslie; Zarnow, Deborah; Johnson, Ann Michelle; Delgado, Jorge; Vossough, Arastoo [The Children' s Hospital of Philadelphia, Radiology Department, Philadelphia, PA (United States); Rubesova, Erika [Stanford University, Department of Radiology, Lucile Packard Children' s Hospital, Stanford, CA (United States)

    2014-04-15

    Several attempts have been made at imaging the fetus at 3 T as part of the continuous search for increased image signal and better anatomical delineation of the developing fetus. Until very recently, imaging of the fetus at 3 T has been disappointing, with numerous artifacts impeding image analysis. Better magnets and coils and improved technology now allow imaging of the fetus at greater magnetic strength, some hurdles in the shape of imaging artifacts notwithstanding. In this paper we present the preliminary experience of evaluating the developing fetus at 3 T and discuss several artifacts encountered and techniques to decrease them, as well as safety concerns associated with scanning the fetus at higher magnetic strength. (orig.)

  3. PET/MRI: a novel hybrid imaging technique. Major clinical indications and preliminary experience in Brazil.

    Science.gov (United States)

    Vitor, Taise; Martins, Karine Minaif; Ionescu, Tudor Mihai; Cunha, Marcelo Livorsi da; Baroni, Ronaldo Hueb; Garcia, Marcio Ricardo Taveira; Wagner, Jairo; Campos, Guilherme de Carvalho; Nogueira, Solange Amorim; Guerra, Elaine Gonçalves; Amaro, Edson

    2017-01-01

    In recent years, medical imaging with hybrid techniques has widely accepted and employed in clinical routine. PET/MRI offers significant advantages, including excellent contrast and resolution and reduced ionizing radiation, as compared to well-established PET/CT. Therefore, PET/MRI is a promising modality for oncologic imaging of some regions, such as brain, head and neck, liver and pelvis. This article set out to analyze clinical conditions that could benefit from PET/MRI imaging based on our caseload. The potential of PET/MRI to become the imaging modality of choice for assessment of neurologic and oncologic conditions associated with soft tissues is highlighted. Clinical aspects of PET/MRI and its application to clinical cases are illustrated with examples extracted from the authors' preliminary experience. RESUMO Nos últimos anos, imagens médicas com tecnologias híbridas tornaram-se amplamente aceitas e utilizadas na prática clínica. O PET/RM possui vantagens importantes, incluindo excelentes contrastes e resolução, e menor radiação ionizante, em comparação ao PET/TC. Por isto, é uma modalidade promissora para exames de imagem de pacientes oncológicos, para avaliar o cérebro, cabeça e pescoço, o fígado e a pelve. O objetivo deste artigo foi analisar as situações clínicas que se beneficiariam de exames de PET/RM a partir de uma casuística. Destacamos o potencial desta técnica se tornar o método de imagem de escolha para doenças neurológicas e oncológicas que envolvam partes moles. Os aspectos clínicos de PET/RM e sua aplicação aos casos clínicos são ilustrados com exemplos da experiência inicial dos autores.

  4. [Low field intra-operative magnetic resonance imaging for brain tumour surgery: preliminary experience].

    Science.gov (United States)

    Roldán, Pedro; García, Sergio; González, Josep; Reyes, Luis Alberto; Torales, Jorge; Valero, Ricard; Oleaga, Laura; Enseñat, Joaquim

    Intra-operative magnetic resonance imaging (iMRI) is a recently introduced tool in the most advanced neurosurgical operating rooms worldwide. We present our preliminary experience in brain tumour surgery with low field PoleStar N30® intraoperative MRI since its introduction in 2013 in the Barcelona Clinic Hospital. A prospective non-randomised study was conducted on cases operated on using iMRI and intention of complete removal up to October 2015. A record was made of the data as regards surgical times, resection rates, histological diagnosis, hospital stay, and survival rates during follow-up. The study included 50 patients, with a mean age of 55 years (±13.7), a preoperative mean Karnofsky of 92 (being 81 post-operatively), and a mean follow-up of 10.5 months (±6.5). There were 26% re-operations due to recurrence. High-grade gliomas were reported in 56%, low-grade gliomas in 24%, and 20% "Other" tumours. Overall hospital stay was 10 days (±4.5). Depending on the histologiacl diagnosis, the "Others" group had a longer hospital stay. Overall, there were 52% complete removal, 18% of maximum removals, and 30% of partial removals. The overall survival rates during follow-up was 84%. iMRI is a safe and effective tool for brain tumour surgery. Its use allows an increase in resection rates, and minimises post-operative complications. Its implementation involves an increase in surgical time, which improves with the characteristic learning curve. More studies are needed to establish its role in the long-term survival of patients. Copyright © 2016 Sociedad Española de Neurocirugía. Publicado por Elsevier España, S.L.U. All rights reserved.

  5. High frame-rate blood vector velocity imaging using plane waves: simulations and preliminary experiments

    DEFF Research Database (Denmark)

    Udesen, J.; Gran, F.; Hansen, K.L.

    2008-01-01

    Conventional ultrasound methods for acquiring color images of blood velocity are limited by a relatively low frame-rate and are restricted to give velocity estimates along the ultrasound beam direction only. To circumvent these limitations, the method presented in this paper uses 3 techniques: 1...... carotid artery of a healthy male was scanned with a scan sequence that satisfies the limits set by the Food and Drug Administration. Vector velocity images were obtained with a frame-rate of 100 Hz where 40 speckle images are used for each vector velocity image. It was found that the blood flow...... approximately followed the vessel wall, and that maximum velocity was approximately 1 m/s, which is a normal value for a healthy person. To further evaluate the method, the test person was scanned with magnetic resonance (MR) angiography. The volume flow derived from the MR scanning was compared with that from...

  6. Postmortem whole-body magnetic resonance imaging as an adjunct to autopsy: preliminary clinical experience.

    Science.gov (United States)

    Patriquin, L; Kassarjian, A; Barish, M; Casserley, L; O'Brien, M; Andry, C; Eustace, S

    2001-02-01

    The purpose of this study was to evaluate whole-body magnetic resonance imaging (MRI) of cadavers as an adjunct to autopsy. Eight consecutive patients underwent both whole-body MRI and autopsy [either conventional (six), limited (one), or percutaneous (one)] within 24 hours of death. Comparison was made of major and minor abnormalities and predicted cause of death recorded by independent readers at both MRI and autopsy. Major discrepancies between the recorded primary cause of death at imaging and autopsy occurred in five (5) patients. These included a myocardial infarction found at autopsy alone, bowel infarction and portal venous gas found at MRI alone, and aortic dissection and occipital infarct found at MRI alone in a patient on whom only limited autopsy was performed. Postmortem MRI may represent a useful adjunct to autopsy, particularly in patients in whom autopsy is limited due to patient/family consent, inoculation risks, and ethnic doctrines.

  7. Electromagnetic image-guided orbital decompression: technique, principles, and preliminary experience with 6 consecutive cases.

    Science.gov (United States)

    Servat, Juan J; Elia, Maxwell Dominic; Gong, Dan; Manes, R Peter; Black, Evan H; Levin, Flora

    2014-12-01

    To assess the feasibility of routine use of electromagnetic image guidance systems in orbital decompression. Six consecutive patients underwent stereotactic-guided three wall orbital decompression using the novel Fusion ENT Navigation System (Medtronic), a portable and expandable electromagnetic guidance system with multi-instrument tracking capabilities. The system consists of the Medtronic LandmarX System software-enabled computer station, signal generator, field-generating magnet, head-mounted marker coil, and surgical tracking instruments. In preparation for use of the LandmarX/Fusion protocol, all patients underwent preoperative non-contrast CT scan from the superior aspect of the frontal sinuses to the inferior aspect of the maxillary sinuses that includes the nasal tip. The Fusion ENT Navigation System (Medtronic™) was used in 6 patients undergoing maximal 3-wall orbital decompression for Graves' orbitopthy after a minimum of six months of disease inactivity. Preoperative Hertel exophthalmometry measured more than 27 mm in all patients. The navigation system proved to be no more difficult technically than the traditional orbital decompression approach. Electromagnetic image guidance is a stereotactic surgical navigation system that provides additional intraoperative flexibility in orbital surgery. Electromagnetic image-guidance offers the ability to perform more aggressive orbital decompressions with reduced risk.

  8. Real-time magnetic resonance imaging of deep venous flow during muscular exercise—preliminary experience

    Science.gov (United States)

    Merboldt, Klaus-Dietmar; Voit, Dirk; Dahm, Johannes; Frahm, Jens

    2016-01-01

    Background The accurate assessment of peripheral venous flow is important for the early diagnosis and treatment of disorders such as deep-vein thrombosis (DVT) which is a major cause of post-thrombotic syndrome or even death due to pulmonary embolism. The aim of this work is to quantitatively determine blood flow in deep veins during rest and muscular exercise using a novel real-time magnetic resonance imaging (MRI) method for velocity-encoded phase-contrast (PC) MRI at high spatiotemporal resolution. Methods Real-time PC MRI of eight healthy volunteers and one patient was performed at 3 Tesla (Prisma fit, Siemens, Erlangen, Germany) using a flexible 16-channel receive coil (Variety, NORAS, Hoechberg, Germany). Acquisitions were based on a highly undersampled radial FLASH sequence with image reconstruction by regularized nonlinear inversion at 0.5×0.5×6 mm3 spatial resolution and 100 ms temporal resolution. Flow was assessed in two cross-sections of the lower leg at the level of the calf muscle and knee using a protocol of 10 s rest, 20 s flexion and extension of the foot, and 10 s rest. Quantitative analyses included through-plane flow in the right posterior tibial, right peroneal and popliteal vein (PC maps) as well as signal intensity changes due to flow and muscle movements (corresponding magnitude images). Results Real-time PC MRI successfully monitored the dynamics of venous flow at high spatiotemporal resolution and clearly demonstrated increased flow in deep veins in response to flexion and extension of the foot. In normal subjects, the maximum velocity (averaged across vessel lumen) during exercise was 9.4±5.7 cm·s−1 for the right peroneal vein, 8.5±4.6 cm·s−1 for the right posterior tibial vein and 17.8±5.8 cm·s−1 for the popliteal vein. The integrated flow volume per exercise (20 s) was 1.9, 1.6 and 50 mL (mean across subjects) for right peroneal, right posterior tibial and popliteal vein, respectively. A patient with DVT presented with

  9. High Frame-Rate Blood Vector Velocity Imaging Using Plane Waves: Simulations and Preliminary Experiments

    DEFF Research Database (Denmark)

    Udesen, Jesper; Gran, Fredrik; Hansen, Kristoffer Lindskov;

    2008-01-01

    Conventional ultrasound methods for acquiring color images of blood velocity are limited by a relatively low frame-rate and are restricted to give velocity estimates along the ultrasound beam direction only. To circumvent these limitations, the method presented in this paper uses 3 techniques: 1......) The ultrasound is not focused during the transmissions of the ultrasound signals; 2) A 13-bit Barker code is transmitted simultaneously from each transducer element; and 3) The 2-D vector velocity of the blood is estimated using 2-D cross-correlation. A parameter study was performed using the Field II program......, and performance of the method was investigated when a virtual blood vessel was scanned by a linear array transducer. An improved parameter set for the method was identified from the parameter study, and a flow rig measurement was performed using the same improved setup as in the simulations. Finally, the common...

  10. MR imaging of the brachial plexus: comparison between 1.5-T and 3-T MR imaging: preliminary experience

    Energy Technology Data Exchange (ETDEWEB)

    Tagliafico, Alberto; Neumaier, Carlo Emanuele; Calabrese, Massimo [National Institute for Cancer Research, Department of Radiology, Genova (Italy); Succio, Giulia; Serafini, Giovanni; Ghidara, Matteo [Santa Corona Hospital, Radiology Department, Savona (Italy); Martinoli, Carlo [Universita di Genova, Radiology Department, Genova (Italy)

    2011-06-15

    To compare 1.5-T and 3-T magnetic resonance (MR) imaging of the brachial plexus. Institutional review board approval and informed consent were obtained from 30 healthy volunteers and 30 consecutive patients with brachial plexus disturbances. MR was prospectively performed with comparable sequence parameters and coils with a 1.5-T and a 3-T system. Imaging protocols at both field strengths included T1-weighted turbo spin-echo (tSE) sequences and T2-weighed turbo spin-echo (tSE) sequences with fat saturation. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) between muscle and nerve were calculated for both field strengths. The visibility of brachial plexus nerve at various anatomic levels (roots, interscalene area, costoclavicular space, and axillary level) was analyzed with a four-point grading scale by two radiologists. MR imaging diagnoses and pathological findings were also compared qualitatively. SNR and CNRs were significantly higher on 3-T MR images than on 1.5-T MR images (Friedman test) for all sequences. Nerve visibility was significantly better on 3-T MR images than on 1.5-T MR images (paired sign test). Pathological findings (n = 30/30) were seen equally well with both field strengths. MR imaging diagnoses did not differ for the 1.5- and 3-T protocols. High-quality MR images of the brachial plexus can be obtained with 3-T MR imaging by using sequences similar to those used at 1.5-T MR imaging. In patients and healthy volunteers, the visibility of nerve trunks and cords at 3-T MR imaging appears to be superior to that at 1.5-T MR imaging. (orig.)

  11. Simultaneous PET/MR head–neck cancer imaging: Preliminary clinical experience and multiparametric evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Covello, M., E-mail: echoplanare@gmail.com [IRCCS SDN, Via E. Gianturco, 111-113 – 80143, Naples (Italy); Cavaliere, C.; Aiello, M.; Cianelli, M.S. [IRCCS SDN, Via E. Gianturco, 111-113 – 80143, Naples (Italy); Mesolella, M.; Iorio, B. [Department of Otorhinolaryngoiatry, Federico II University, Naples (Italy); Rossi, A.; Nicolai, E. [IRCCS SDN, Via E. Gianturco, 111-113 – 80143, Naples (Italy)

    2015-07-15

    Highlights: • Simultaneous PET/MRI is a suitable tool for head/neck T-staging. • No significant differences have been found for PET measures get by both PET/CT and PET/MRI. • SUV 2D and 3D measures in HN lesion offer comparable estimations. • Multiparametric evaluation allows a complete characterization of HN lesions. - Abstract: Purpose: To evaluate the role of simultaneous hybrid PET/MR imaging and to correlate metabolic PET data with morpho-functional parameters derived by MRI in patients with head–neck cancer. Methods: Forty-four patients, with histologically confirmed head and neck malignancy (22 primary tumors and 22 follow-up) were studied. Patients initially received a clinical exam and endoscopy with direct biopsy. Next patients underwent whole body PET/CT followed by PET/MR of the head/neck region. PET and MRI studies were separately evaluated by two blinded groups (both included one radiologist and one nuclear physician) in order to define the presence or absence of lesions/recurrences. Regions of interest (ROIs) analysis was conducted on the primary lesion at the level of maximum size on metabolic (SUV and MTV), diffusion (ADC) and perfusion (K{sup trans}, V{sub e}, k{sub ep} and iAUC) parameters. Results: PET/MR examinations were successfully performed on all 44 patients. Agreement between the two blinded groups was found in anatomic allocation of lesions by PET/MR (Primary tumors: Cohen's kappa 0.93; Follow-up: Cohen's kappa 0.89). There was a significant correlation between CT-SUV measures and MR (e.g., CT-SUV VOI vs. MR-SUV VOI: ρ = 0.97, p < 0.001 for the entire sample). There was also significant positive correlations between the ROI area, SUV measures, and the metabolic parameters (SUV and MTV) obtained during both PET/CT and PET/MR. A significant negative correlation was observed between ADC and K{sup trans} values in the primary tumors. In addition, a significant negative correlation existed between MR SUV and ADC in

  12. Testicular microlithiasis and preliminary experience of acoustic radiation force impulse imaging

    Science.gov (United States)

    Osther, Palle Jørn Sloth; Rafaelsen, Søren Rafael

    2016-01-01

    Background Elastography of the testis can be used as a part of multiparametric examination of the scrotum. Purpose To determine the testicular stiffness using acoustic radiation force impulse imaging (ARFI) technique in men with testicular microlithiasis (TML). Material and Methods In 2013, 12 patients with diagnosed testicular microlithiasis in 2008 (mean age, 51 years; age range, 25–76 years) underwent a 5-year follow-up B-mode ultrasonography with three ARFI elastography measurements of each testis. We used a Siemens Acuson S3000 machine. Results No malignancy was found at the 5-year follow-up B-mode and elastography in 2013. However, we found an increase in TML; in the previous ultrasonography in 2008, eight men had bilateral TML, whereas in 2013, 10 men were diagnosed with bilateral TML. The mean elasticity of testicles with TML was 0.82 m/s (interquartile range [IQR], 0.72–0.88 m/s; range, 65–1.08 m/s). Conclusion Elastography velocity of testis with TML seems to be in the same velocity range as in men with normal testis tissue. PMID:27504193

  13. Use of movable high-field-strength intraoperative magnetic resonance imaging with awake craniotomies for resection of gliomas: preliminary experience.

    LENUS (Irish Health Repository)

    Leuthardt, Eric C

    2011-07-01

    Awake craniotomy with electrocortical mapping and intraoperative magnetic resonance imaging (iMRI) are established techniques for maximizing tumor resection and preserving function, but there has been little experience combining these methodologies.

  14. Turbo STIR magnetic resonance imaging as a whole-body screening tool for metastases in patients with breast carcinoma: preliminary clinical experience.

    Science.gov (United States)

    Walker, R; Kessar, P; Blanchard, R; Dimasi, M; Harper, K; DeCarvalho, V; Yucel, E K; Patriquin, L; Eustace, S

    2000-04-01

    This study was undertaken to assess the utility of whole-body turbo short tau inversion recovery (STIR) magnetic resonance imaging (MRI) to detect metastases to liver, brain, and bone as a single examination in women with breast cancer. Seventeen patients with biopsy-proven breast cancer and suspected metastatic disease attending over a 12-month period referred for both conventional imaging and whole-body MRI were included in the study. Three patients were found to be free of metastases at both conventional and MR imaging. Appendicular or axial skeletal metastases were identified in 11 of 17 patients, with correlation between findings at whole-body MRI and scintigraphy in 15 of the 17 patients. Five patients had evidence of hepatic metastases on whole-body MRI, of which metastases were identified in only three patients at CT despite contrast enhancement. Four patients had brain abnormalities (metastases in three patients, meningioma in one patient) detected on both whole-body and dedicated brain MRI. Preliminary clinical experience suggests that turbo STIR whole-body MRI may represent a convenient and cost-effective method of total body screening for metastases in patients with breast carcinoma.

  15. Using corrected Cone-Beam CT image for accelerated partial breast irradiation treatment dose verification: the preliminary experience

    OpenAIRE

    Wang, Jiazhou; Hu, Weigang; Cai, Gang; Peng, Jiayuan; Pan, Ziqiang; Guo, Xiaomao; Chen, Jiayi

    2013-01-01

    Background Accurate target localization is mandatory in the accelerated partial breast irradiation (APBI) delivery. Dosimetric verification for positional error will further guarantee the accuracy of treatment delivery. The purpose of this study is to evaluate the clinical feasibility of a cone beam computer tomographic (CBCT) image correction method in APBI. Methods A CBCT image correction method was developed. First, rigid image registration was proceeded for CTs and CBCTs; second, these im...

  16. Preliminary Experience Using Eye-Tracking Technology to Differentiate Novice and Expert Image Interpretation for Ultrasound-Guided Regional Anesthesia.

    Science.gov (United States)

    Borg, Lindsay K; Harrison, T Kyle; Kou, Alex; Mariano, Edward R; Udani, Ankeet D; Kim, T Edward; Shum, Cynthia; Howard, Steven K

    2017-08-04

    Objective measures are needed to guide the novice's pathway to expertise. Within and outside medicine, eye tracking has been used for both training and assessment. We designed this study to test the hypothesis that eye tracking may differentiate novices from experts in static image interpretation for ultrasound (US)-guided regional anesthesia. We recruited novice anesthesiology residents and regional anesthesiology experts. Participants wore eye-tracking glasses, were shown 5 sonograms of US-guided regional anesthesia, and were asked a series of anatomy-based questions related to each image while their eye movements were recorded. The answer to each question was a location on the sonogram, defined as the area of interest (AOI). The primary outcome was the total gaze time in the AOI (seconds). Secondary outcomes were the total gaze time outside the AOI (seconds), total time to answer (seconds), and time to first fixation on the AOI (seconds). Five novices and 5 experts completed the study. Although the gaze time (mean ± SD) in the AOI was not different between groups (7 ± 4 seconds for novices and 7 ± 3 seconds for experts; P = .150), the gaze time outside the AOI was greater for novices (75 ± 18 versus 44 ± 4 seconds for experts; P = .005). The total time to answer and total time to first fixation in the AOI were both shorter for experts. Experts in US-guided regional anesthesia take less time to identify sonoanatomy and spend less unfocused time away from a target compared to novices. Eye tracking is a potentially useful tool to differentiate novices from experts in the domain of US image interpretation. © 2017 by the American Institute of Ultrasound in Medicine.

  17. Cancer and diverticulitis of the sigmoid colon. Differentiation with computed tomography versus magnetic resonance imaging - Preliminary experiences

    Energy Technology Data Exchange (ETDEWEB)

    Oeistaemoe, Emma; Hjern, Fredrik; Abraham-Nordling, Mirna [Dept. of Clinical Sciences, Div. of Surgery, Danderyd Hospital, Karolinska Institutet, Stockholm (Sweden)], e-mail: mirna.abraham.nordling@ki.se; Blomqvist, Lennart [Dept. of Diagnostic Radiology, Dept. of Molecular Medicine and Surgery Karolinska Univ. Hospital Solna and Karolinska Institutet, Stockholm (Sweden); Von Heijne, Anders [Dept. of Clinical Sciences, Div. of Radiology, Danderyd Hospital, Karolinska Institutet, Stockholm (Sweden)

    2013-04-15

    Background: Both colon cancer and diverticular disease are common in the Western world. A challenge when patients present with clinical findings is that both diseases can present with symptoms that may mimic the other. Purpose: To determine whether magnetic resonance imaging (MRI) could be helpful to differentiate between diverticulitis and cancer of the sigmoid colon compared to the differentiation offered by evaluation of multidetector computed tomography (CT) in a clinical situation. Material and Methods: Thirty patients were consecutively included. Fifteen patients were under work-up for a recently diagnosed sigmoid cancer and 15 patients had recently been treated in hospital due to first-time acute sigmoid diverticulitis. All patients underwent CT, T2- weighted MRI and diffusion-weighted MRI. Anonymized examinations were retrospectively presented in random order to one experienced radiologist. Results: With contrast-enhanced CT, the sensitivity and specificity for diagnosis of cancer and diverticulitis were 66.7% (10/15) and 93.3% (14/15), respectively. Using T2-weighted and diffusion-weighted MR images, the sensitivity and specificity for diagnosis of cancer and diverticulitis were 100% (14/14) and 100% (14/14), respectively. Conclusion: MRI provides information that may contribute to improve the differentiation between sigmoid cancer and diverticulitis that is offered by CT. These encouraging results need to be confirmed in a larger study.

  18. Coronary artery imaging during preoperative CT staging: preliminary experience with 64-slice multidetector CT in 99 consecutive patients

    Energy Technology Data Exchange (ETDEWEB)

    Delhaye, Damien; Remy-Jardin, Martine; Rozel, Celine; Remy, Jacques [University Center of Lille, Boulevard Jules Leclerc, Department of Thoracic Imaging, Hospital Calmette, Lille cedex (France); Dusson, Catherine; Wurtz, Alain [University Center of Lille, Department of Thoracic Surgery, Hospital Calmette, Lille cedex (France); Delannoy-Deken, Valerie; Duhamel, Alain [University of Lille, Department of Medical Statistics, Lille cedex (France)

    2007-03-15

    The purpose of this study was to evaluate the clinical feasibility of coronary artery imaging during routine preoperative 64-slice MDCT scans of the chest. Ninety-nine consecutive patients in sinus rhythm underwent a biphasic multidetector-row spiral CT examination of the chest without the administration of beta-blockers, including an ECG-gated acquisition over the cardiac cavities, followed by a non-gated examination of the upper third of the thorax. Data were reconstructed to evaluate coronary arteries and to obtain presurgical staging of the underlying disease. The percentage of assessable segments ranged from 65.4% (972/1,485) when considering all coronary artery segments to 88% (613/693) for the proximal and mid segments, reaching 98% (387/396) for proximal coronary artery segments. The 387 interpretable proximal segments included 97 (97%) LM, 99 (100%) LAD, 96 (97%) LCX and 95 (96%) RCA with a mean attenuation of 280.70{+-}52.93 HU. The mean percentage of assessable segments was significantly higher in patients with a heart rate {<=}80 bpm (n=48) than in patients with a heart rate greater than 80 bpm (n=35) (80{+-}11% vs. 72{+-}13%; P=0.0008). Diagnostic image quality was achieved in all patients for preoperative staging of the underlying disorder. The mean estimated effective dose was 12.06{+-}3.25 mSv for ECG-gated scans and 13.88{+-}3.49 mSv for complete chest examinations. Proximal and mid-coronary artery segments can be adequately evaluated during presurgical CT examinations of the chest obtained with 64-slice MDCT without the administration of {beta}-blockers. (orig.)

  19. Application of IR and NIR fiber optic imaging in thermographic and spectroscopic diagnosis of atherosclerotic vulnerable plaques: preliminary experience

    Science.gov (United States)

    Naghavi, Morteza; Khan, Tania; Gu, Bujin; Soller, Babs R.; Melling, Peter; Asif, Mohammed; Gul, Khawar; Madjid, Mohammad; Casscells, S. W.; Willerson, James T.

    2000-12-01

    Despite major advances in cardiovascular science and technology during the past three decades, approximately half of all myocardial infarctions and sudden deaths occur unexpectedly. It is widely accepted that coronary atherosclerotic plaques and thrombotic complications resulting from their rupture or erosion are the underlying causes of this major health problem. The majority of these vulnerable plaques exhibit active inflammation, a large necrotic lipid core, a thin fibrous cap, and confer a stenosis of less than 70%. These lesions are not detectable by stress testing or coronary angiography. Our group is exploring the possibility of a functional classification based on physiological variables such as plaque temperature, pH, oxygen consumption, lactate production etc. We have shown that heat accurately locates the inflamed plaques. We also demonstrated human atherosclerotic plaques are heterogeneous with regard to pH and hot plaques and are more likely to be acidic. To develop a nonsurgical method for locating the inflamed plaques, we are developing both IR fiber optic imaging and NIR spectroscopic systems in our laboratory to detect hot and acidic plaque in atherosclerotic arterial walls. Our findings introduce the possibility of an isolated/combined IR and NIR fiber optic catheter that can bring new insight into functional assessment of atherosclerotic plaque and thereby detection of active and inflamed lesions responsible for heart attacks and strokes.

  20. Intra-epiphyseal stress injury of the proximal tibial epiphysis: Preliminary experience of magnetic resonance imaging findings

    Energy Technology Data Exchange (ETDEWEB)

    Tony, G., E-mail: drgtony@gmail.com [Stafford General Hospital, Weston Road, Stafford, Staffordshire ST16 3SA (United Kingdom); Charran, A., E-mail: amandacharran@yahoo.com [Hillingdon Hospital, Pield Heath Rd, Uxbridge, Middlesex UB8 3NN (United Kingdom); Tins, B., E-mail: bernhard.tins@rjah.nhs.uk [Department of Diagnostic Imaging, Robert Jones and Agnes Hunt, Orthopaedic Hospital, Oswestry, Shropshire SY10 7 AG (United Kingdom); Lalam, R., E-mail: radhesh.lalam@rjah.nhs.uk [Department of Diagnostic Imaging, Robert Jones and Agnes Hunt, Orthopaedic Hospital, Oswestry, Shropshire SY10 7 AG (United Kingdom); Tyrrell, P.N.M., E-mail: prudencia.tyrrell@rjah.nhs.uk [Department of Diagnostic Imaging, Robert Jones and Agnes Hunt, Orthopaedic Hospital, Oswestry, Shropshire SY10 7 AG (United Kingdom); Singh, J., E-mail: jaspreet.singh@rjah.nhs.uk [Department of Diagnostic Imaging, Robert Jones and Agnes Hunt, Orthopaedic Hospital, Oswestry, Shropshire SY10 7 AG (United Kingdom); Cool, P., E-mail: paul.cool@rjah.nhs.uk [Orthopaedic Oncology, Robert Jones and Agnes Hunt, Orthopaedic Hospital, Oswestry, Shropshire SY10 7 AG (United Kingdom); Kiely, N., E-mail: nigel.kiely@rjah.nhs.uk [Paediatric Orthopaedics, Robert Jones and Agnes Hunt, Orthopaedic Hospital, Oswestry, Shropshire SY10 7 AG (United Kingdom); Cassar-Pullicino, V.N., E-mail: Victor.Pullicino@rjah.nhs.uk [Department of Diagnostic Imaging, Robert Jones and Agnes Hunt, Orthopaedic Hospital, Oswestry, Shropshire SY10 7 AG (United Kingdom)

    2014-11-15

    Highlights: • Purely intra-epiphyseal stress injuries of the proximal tibial epiphysis are described for the first time. • The variation in the MRI findings of these injuries depending on the stage of maturation is demonstrated. • We postulate a patho-mechanism to explain the variations in site and appearance of stress injuries in this region. - Abstract: Stress induced injuries affecting the physeal plate or cortical bone in children and adolescents, especially young athletes, have been well described. However, there are no reports in the current English language literature of stress injury affecting the incompletely ossified epiphyseal cartilage. We present four cases of stress related change to the proximal tibial epiphysis (PTE) along with their respective magnetic resonance imaging (MRI) appearances ranging from subtle oedema signal to a pseudo-tumour like appearance within the epiphyseal cartilage. The site and pattern of intra-epiphyseal injury is determined by the type of tissue that is affected, the maturity of the skeleton and the type of forces that are transmitted through the tissue. We demonstrate how an awareness of the morphological spectrum of MRI appearances in intra-epiphyseal stress injury and the ability to identify concomitant signs of stress in other nearby structures can help reduce misdiagnosis, avoid invasive diagnostic procedures like bone biopsy and reassure patients and their families.

  1. Diffusion-weighted MR imaging for the diagnosis of abscess complicating fistula-in-ano: preliminary experience

    Energy Technology Data Exchange (ETDEWEB)

    Dohan, Anthony; Soyer, Philippe [Hopital Lariboisiere, Assistance Publique-Hopitaux de Paris, Department of Body and Interventional Imaging, Paris Cedex 10 (France); Universite Paris-Diderot, Sorbonne Paris Cite, Paris (France); Eveno, Clarisse; Pocard, Marc [Universite Paris-Diderot, Sorbonne Paris Cite, Paris (France); Hopital Lariboisiere, Assistance Publique-Hopitaux de Paris, Surgical Oncologic and Digestive Unit, Paris Cedex 10 (France); Oprea, Raluca; Place, Vinciane; Boudiaf, Mourad [Hopital Lariboisiere, Assistance Publique-Hopitaux de Paris, Department of Body and Interventional Imaging, Paris Cedex 10 (France); Pautrat, Karine [Hopital Lariboisiere, Assistance Publique-Hopitaux de Paris, Surgical Oncologic and Digestive Unit, Paris Cedex 10 (France); Hoeffel, Christine [Hopital Robert-Debre, Department of Radiology, Reims Cedex (France)

    2014-11-15

    To investigate the role of diffusion-weighted magnetic resonance imaging (DWMRI) in the diagnosis of abscess-complicating fistula-in-ano. This retrospective study was approved by our Institutional Review Board and informed consent was waived. MRI examinations, including fat-suppressed T2-weighted turbo spin-echo (T2-TSE) MRI and DWMRI, of 24 patients with a fistula-in-ano, were reviewed by two independent readers for the presence and number of visible fistulas, conspicuity and apparent diffusion coefficient (ADC) measurement of suspected fistula tracks and pelvic collections. The reference standard was surgical with follow-up findings. Sensitivity was 91.2 % [95 % CI: 76 %-98 %] for T2-weighted TSE MRI and 100 % [95 % CI: 90 %-100 %] for DWMRI detecting fistulas. ADC values were lower in abscesses than in inflammatory masses (P = 0.714.10{sup -6}). The area under the ROC curve was 0.971 and the optimal cut-off ADC value was 1.186 x 10{sup -3} mm{sup 2}/s, yielding a sensitivity of 100 % [95 % CI: 77 %-100 %], a specificity of 90 % [95 % CI: 66 %-100 %], a positive predictive value of 93 % [95 % CI: 82.8 %-100 %] and a negative predictive value of 90 % [95 % CI: 78 %-100 %] for an abscess diagnosis. Fistula conspicuity was greater with DWMRI than with T2-TSE MRI for the two observers (P = 0.0034 and P = 0.0007). DWMRI shows high sensitivity and specificity for the diagnosis of perianal abscesses and helps discriminate between an abscess and inflammatory mass. Conspicuity of fistulas-in-ano is greater with DWMRI than with T2-weighted TSE MRI. (orig.)

  2. Rayleigh-wave imaging of upper-mantle shear velocities beneath the Malawi Rift; Preliminary results from the SEGMeNT experiment

    Science.gov (United States)

    Accardo, N. J.; Gaherty, J. B.; Shillington, D. J.; Nyblade, A.; Ebinger, C. J.; Mbogoni, G. J.; Chindandali, P. R. N.; Mulibo, G. D.; Ferdinand-Wambura, R.; Kamihanda, G.

    2015-12-01

    The Malawi Rift (MR) is an immature rift located at the southern tip of the Western branch of the East African Rift System (EARS). Pronounced border faults and tectonic segmentation are seen within the upper crust. Surface volcanism in the region is limited to the Rungwe volcanic province located north of Lake Malawi (Nyasa). However, the distribution of extension and magma at depth in the crust and mantle lithosphere is unknown. As the Western Rift of the EARS is largely magma-poor except for discrete volcanic provinces, the MR presents the ideal location to elucidate the role of magmatism in early-stage rifting and the manifestation of segmentation at depth. This study investigates the shear velocity of the crust and mantle lithosphere beneath the MR to constrain the thermal structure, the amount of total crustal and lithospheric thinning, and the presence and distribution of magmatism beneath the rift. Utilizing 55 stations from the SEGMeNT (Study of Extension and maGmatism in Malawi aNd Tanzania) passive-source seismic experiment operating in Malawi and Tanzania, we employed a multi-channel cross-correlation algorithm to obtain inter-station phase and amplitude information from Rayleigh wave observations between 20 and 80 s period. We retrieve estimates of phase velocity between 9-20 s period from ambient noise cross-correlograms in the frequency domain via Aki's formula. We invert phase velocity measurements to obtain estimates of shear velocity (Vs) between 50-200 km depth. Preliminary results reveal a striking low-velocity zone (LVZ) beneath the Rungwe volcanic province with Vs ~4.2-4.3 km/s in the uppermost mantle. Low velocities extend along the entire strike of Lake Malawi and to the west where a faster velocity lid (~4.5 km/s) is imaged. These preliminary results will be extended by incorporating broadband data from seven "lake"-bottom seismometers (LBS) to be retrieved from Lake Malawi in October of this year. The crust and mantle modeling will be

  3. Preliminary Clinical Experience of trans-1-Amino-3-(18F-fluorocyclobutanecarboxylic Acid (anti-(18F-FACBC PET/CT Imaging in Prostate Cancer Patients

    Directory of Open Access Journals (Sweden)

    Kalevi Kairemo

    2014-01-01

    Full Text Available Background. In this retrospective analysis we assessed the role of [18F]-FACBC-PET/CT in the prostatic cancer staging. Procedure. 30 first [18F]-FACBC-PET/CT images of 26 patients (68.1 ± 5.8 years were analyzed. PET/CT findings were compared with PSA concentrations, with PSA doubling times (PDT, and with correlative imaging. Results. On 16 [18F]-FACBC (53.3% scans, 58 metabolically active lesions were found. 12 (20.7% lesions corresponding to the local relapse were found in prostate/prostate bed and seminal vesicles, 9 (15.5% lesions were located in regional lymph nodes, 10 (17.2% were located in distal lymph nodes, and 26 (44.8% metabolically active lesions were found in the skeleton. In one case, focal uptake was found in the brain, confirmed further on MRI as meningioma. The mean S-PSA level in patients with positive [18F]-FACBC findings was 9.5 ± 16.9 μg/L (0.54–69 μg/L and in patients with negative [18F]-FACBC findings was 1.96 ± 1.87 μg/L (0.11–5.9 μg/L, but the difference was not statistically significant. However, the PSA doubling time (PDT in patients with positive findings was significantly shorter than PDT in patients with negative findings: 3.25 ± 2.09 months (0.3–6 months versus 31.2 ± 22.02 months (8–84 months, P<0.0001. There was a strong positive correlation between PSA value and number of metabolically active lesions (R=0.74 and a negative correlation between PDT and number of metabolically active lesions (R=-0.56. There was a weak negative correlation between PDT and SUVmax⁡ (R=-0.30. Conclusion. According to our preliminary clinical experience, [18F]-FACBC-PET may play a role in in vivo restaging of an active prostate cancer, especially in patients with a short S-PSA doubling time.

  4. Sentinel Node Mapping Using Indocyanine Green and Near-infrared Fluorescence Imaging Technology for Uterine Malignancies: Preliminary Experience With the Da Vinci Xi System.

    Science.gov (United States)

    Siesto, Gabriele; Romano, Fabrizio; Fiamengo, Barbara; Vitobello, Domenico

    2016-01-01

    Sentinel lymph node (SLN) mapping has emerged as the new frontier for the surgical staging of apparently early-stage cervical and endometrial cancer. Different colorimetric and radioactive tracers, alone and in combination, have been proposed with encouraging results. Fluorometric mapping using indocyanine green (ICG) appears to be a suitable and attractive alternative to provide reliable staging [1-4]. In this video, we present the technique of SLN mapping in 2 cases (1 endometrial and 1 cervical cancer, respectively) using ICG and the near-infrared technology provided by the newest Da Vinci Xi robotic system (Intuitive Surgical Inc., Sunnyvale, CA). Together we report the results of our preliminary experience on the first 20 cases performed. The new robotic Da Vinci Xi system was available at our institution since May 2015. Upon institutional review board/ethical committee approval, all consecutive patients with early-stage endometrial and cervical cancer who were judged suitable for robotic surgery have been enrolled for SLN mapping with ICG. We adopted the Memorial Sloan Kettering Cancer Center SLN algorithm; the tracer was delivered into the cervix in all cases. Four milliliters (1.25 mg/mL) of ICG was injected divided into the 3- and 9-o'clock positions of the cervix alone, with 1 mL deep into the stroma and 1 mL submucosally at the skin incision. Sentinel lymph nodes were examined with a protocol including both ultrastaging with immunohistochemistry [3] and 1-step nucleic acid amplification assay [5,6] under a parallel protocol of study. During the study period, 20 cases were managed; 14 and 6 patients had endometrial and cervical cancer, respectively. SLN was detected in all cases (20/20, 100%). Bilateral SLNs were detected in 17 of 20 (85.0%) cases. Based on preoperative and intraoperative findings, 13 (65.0%) patients received systematic pelvic lymphadenectomy after SLN mapping. Three (15.0%) patients had microscopic nodal metastases on SLN. No

  5. PET/MRI: a novel hybrid imaging technique: major clinical indications and preliminary experience in Brazil; PET/RM: um novo metodo de imagem hibrida: principais indicacoes clinicas e experiencia preliminar no Brasil

    Energy Technology Data Exchange (ETDEWEB)

    Vitor, Taise; Martins, Karine Minaif; Ionescu, Tudor Mihai and others, E-mail: taisevitor@gmail.com [Hospital Israelita Albert Einstein, Sao Paulo, SP (Brazil)

    2017-04-01

    In recent years, medical imaging with hybrid techniques has widely accepted and employed in clinical routine. PET/MRI offers significant advantages, including excellent contrast and resolution and reduced ionizing radiation, as compared to well-established PET/ CT. Therefore, PET/MRI is a promising modality for oncologic imaging of some regions, such as brain, head and neck, liver and pelvis. This article set out to analyze clinical conditions that could benefit from PET/MRI imaging based on our caseload. The potential of PET/MRI to become the imaging modality of choice for assessment of neurologic and oncologic conditions associated with soft tissues is highlighted. Clinical aspects of PET/MRI and its application to clinical cases are illustrated with examples extracted from the authors' preliminary experience. (author)

  6. Preliminary experiments on quantification of skin condition

    Science.gov (United States)

    Kitajima, Kenzo; Iyatomi, Hitoshi

    2014-03-01

    In this study, we investigated a preliminary assessment method for skin conditions such as a moisturizing property and its fineness of the skin with an image analysis only. We captured a facial images from volunteer subjects aged between 30s and 60s by Pocket Micro (R) device (Scalar Co., Japan). This device has two image capturing modes; the normal mode and the non-reflection mode with the aid of the equipped polarization filter. We captured skin images from a total of 68 spots from subjects' face using both modes (i.e. total of 136 skin images). The moisture-retaining property of the skin and subjective evaluation score of the skin fineness in 5-point scale for each case were also obtained in advance as a gold standard (their mean and SD were 35.15 +/- 3.22 (μS) and 3.45 +/- 1.17, respectively). We extracted a total of 107 image features from each image and built linear regression models for estimating abovementioned criteria with a stepwise feature selection. The developed model for estimating the skin moisture achieved the MSE of 1.92 (μS) with 6 selected parameters, while the model for skin fineness achieved that of 0.51 scales with 7 parameters under the leave-one-out cross validation. We confirmed the developed models predicted the moisture-retaining property and fineness of the skin appropriately with only captured image.

  7. Tree STEM Reconstruction Using Vertical Fisheye Images: a Preliminary Study

    Science.gov (United States)

    Berveglieri, A.; Tommaselli, A. M. G.

    2016-06-01

    A preliminary study was conducted to assess a tree stem reconstruction technique with panoramic images taken with fisheye lenses. The concept is similar to the Structure from Motion (SfM) technique, but the acquisition and data preparation rely on fisheye cameras to generate a vertical image sequence with height variations of the camera station. Each vertical image is rectified to four vertical planes, producing horizontal lateral views. The stems in the lateral view are rectified to the same scale in the image sequence to facilitate image matching. Using bundle adjustment, the stems are reconstructed, enabling later measurement and extraction of several attributes. The 3D reconstruction was performed with the proposed technique and compared with SfM. The preliminary results showed that the stems were correctly reconstructed by using the lateral virtual images generated from the vertical fisheye images and with the advantage of using fewer images and taken from one single station.

  8. TREE STEM RECONSTRUCTION USING VERTICAL FISHEYE IMAGES: A PRELIMINARY STUDY

    Directory of Open Access Journals (Sweden)

    A. Berveglieri

    2016-06-01

    Full Text Available A preliminary study was conducted to assess a tree stem reconstruction technique with panoramic images taken with fisheye lenses. The concept is similar to the Structure from Motion (SfM technique, but the acquisition and data preparation rely on fisheye cameras to generate a vertical image sequence with height variations of the camera station. Each vertical image is rectified to four vertical planes, producing horizontal lateral views. The stems in the lateral view are rectified to the same scale in the image sequence to facilitate image matching. Using bundle adjustment, the stems are reconstructed, enabling later measurement and extraction of several attributes. The 3D reconstruction was performed with the proposed technique and compared with SfM. The preliminary results showed that the stems were correctly reconstructed by using the lateral virtual images generated from the vertical fisheye images and with the advantage of using fewer images and taken from one single station.

  9. Coronary imaging quality in routine ECG-gated multidetector CT examinations of the entire thorax: preliminary experience with a 64-slice CT system in 133 patients

    Energy Technology Data Exchange (ETDEWEB)

    Delhaye, Damien; Remy-Jardin, Martine; Salem, Randa; Teisseire, Antoine; Khalil, Chadi; Remy, Jacques [Hospital Calmette, University Center of Lille, Department of Thoracic Imaging, Lille Cedex (France); Delannoy-Deken, Valerie; Duhamel, Alain [University of Lille, Department of Medical Statistics, Lille Cedex (France)

    2007-04-15

    To evaluate image quality in the assessment of the coronary arteries during routine ECG-gated multidetector CT (MDCT) of the chest. One hundred and thirty three patients in sinus rhythm underwent an ECG-gated CT angiographic examination of the entire chest without {beta}-blockers with a 64-slice CT system. In 127 patients (95%), it was possible to assess the coronary arteries partially or totally; coronary artery imaging failed in six patients (5%), leading to a detailed description of the coronary arteries in 127 patients. Considering ten coronary artery segments per patient, 75% of coronary segments were assessable (948/1270 segments). When the distal segments were excluded from the analysis (i.e., seven coronary segments evaluated per patient), the percentage of assessable segments was 86% (768/889 proximal and mid coronary segments) and reached 93% (474/508) when assessing proximal segments exclusively. The mean number of assessable segments was significantly higher in patients with a heart rate {<=}80 bpm (n=95) than in patients with a heart rate >80 bpm (n=38) (p<0.002). Proximal and mid-coronary segments can be adequately assessed during a whole-chest ECG-gated CT angiographic examination without administration of {beta}-blockers in patients with a heart rate below 80 bpm. (orig.)

  10. Blood oxygenation level-dependent MR imaging as a predictor of therapeutic response to concurrent chemoradiotherapy in cervical cancer: a preliminary experience

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chan Kyo; Park, Sung Yoon; Park, Byung Kwan [Sungkyunkwan University School of Medicine, Department of Radiology and Center for Imaging Science, Samsung Medical Center, Seoul (Korea, Republic of); Park, Won; Huh, Seung Jae [Sungkyunkwan University School of Medicine, Department of Radiation Oncology, Samsung Medical Center, Seoul (Korea, Republic of)

    2014-07-15

    To investigate the value of blood oxygenation level-dependent (BOLD) magnetic resonance imaging (MRI) as a predictor of therapeutic response in cervical cancer patients undergoing concurrent chemoradiotherapy (CCRT). Thirty consecutive patients with biopsy-proven cervical cancer were examined by BOLD MRI before (preTx) and after CCRT (postTx). The R2* value (s{sup -1}) was calculated in the tumour and normal myometrium for preTx and postTx studies. Final tumour responses, as determined by changes of tumour size or volume on MRI, were correlated with tumour R2* values at preTx. The mean R2* values of tumours at preTx (21.1) were significantly lower than those at postTx (39.4 s{sup -1}) (p < 0.001), while those of normal myometrium were similar between preTx and postTx (p = 0.363). At preTx, tumour R2* values showed significantly negative correlation with final tumour size response (p = 0.022, Spearman's coefficient = -0.415). However, tumour R2* values at preTx were not associated with final tumour volume response (p = 0.069). BOLD MRI at 3 T, as an imaging biomarker, may have the potential to evaluate therapeutic response in cervical cancers. The association between BOLD MRI findings and CCRT responses warrants further validation. (orig.)

  11. Imaging the Alpine Fault: preliminary results from a detailed 3D-VSP experiment at the DFDP-2 drill site in Whataroa, New Zealand

    Science.gov (United States)

    Lay, Vera; Bodenburg, Sascha; Buske, Stefan; Townend, John; Kellett, Richard; Savage, Martha; Schmitt, Douglas; Constantinou, Alexis; Eccles, Jennifer; Lawton, Donald; Hall, Kevin; Bertram, Malcolm; Gorman, Andrew

    2017-04-01

    The plate-bounding Alpine Fault in New Zealand is an 850 km long transpressive continental fault zone that is late in its earthquake cycle. The Deep Fault Drilling Project (DFDP) aims to deliver insight into the geological structure of this fault zone and its evolution by drilling and sampling the Alpine Fault at depth. Previously analysed 2D reflection seismic data image the main Alpine Fault reflector at a depth of 1.5-2.2 km with a dip of approximately 48° to the southeast below the DFDP-2 borehole. Additionally, there are indications of a more complex 3D fault structure with several fault branches which have not yet been clearly imaged in detail. For that reason we acquired a 3D-VSP seismic data set at the DFDP-2 drill site in January 2016. A zero-offset VSP and a walk-away VSP survey were conducted using a Vibroseis source. Within the borehole, a permanently installed "Distributed Acoustic Fibre Optic Cable" (down to 893 m) and a 3C Sercel slimwave tool (down to 400 m) were used to record the seismic wavefield. In addition, an array of 160 three-component receivers with a spacing of 10 m perpendicular and 20 m parallel to the main strike of the Alpine Fault was set up and moved successively along the valley to record reflections from the main Alpine Fault zone over a broad depth range and to derive a detailed 3D tomographic velocity model in the hanging wall. We will show a detailed 3D velocity model derived from first-arrival traveltime tomography. Subsets of the whole data set were analysed separately to estimate the corresponding ray coverage and the reliability of the observed features in the obtained velocity model. By testing various inversion parameters and starting models, we derived a detailed near-surface velocity model that reveals the significance of the old glacial valley structures. Hence, this new 3D model improves the velocity model derived previously from a 2D seismic profile line in that area. Furthermore, processing of the dense 3C data

  12. Voyager imaging experiment

    Science.gov (United States)

    Smith, B.A.; Briggs, G.A.; Danielson, G.E.; Cook, A.F.; Davies, M.E.; Hunt, G.E.; Masursky, H.; Soderblom, L.A.; Owen, T.C.; Sagan, C.; Suomi, V.E.

    1977-01-01

    The overall objective of this experiment is exploratory reconnaissance of Jupiter, Saturn, their satellites, and Saturn's rings. Such reconnaissance, at resolutions and phase angles unobtainable from Earth, can be expected to provide much new data relevant to the atmospheric and/or surface properties of these bodies. The experiment also has the following specific objectives: Observe and characterize the global circulation of the atmospheres of Jupiter and Saturn; Determine the horizontal and vertical structure of the visible clouds and establish their relationship to the belted appearance and dynamical properties of the planetary atmospheres; Determine the vertical structure of high, optically-thin, scattering layers on Jupiter and Saturn; Determine the nature of anomalous features such as the Great Red Spot, South Equatorial Belt disturbances, etc.; Characterize the nature of the colored material in the clouds of Jupiter and Saturn, and identify the nature and sources of chromophores on Io and Titan; Perform comparative geologic studies of many satellites at less than 15-km resolution; Map and characterize the geologic structure of several satellites at high resolution (???1 km); Investigate the existence and nature of atmospheres on the satellites; Determine the mass, size, and shape of many of the satellites by direct measurement; Determine the direction of the spin axes and periods of rotation of several satellites, and establish coordinate systems for the larger satellites; Map the radial distribution of material in Saturn's rings at high resolution; Determine the optical scattering properties of the primaries, rings, and satellites at several wavelengths and phase angles; Search for novel physical phenomena, e.g., phenomena associated with the Io flux tube, meteors, aurorae, lightning, or satellite shadows. ?? 1977 D. Reidel Publishing Company.

  13. Portable Imaging Polarimeter and Imaging Experiments

    Energy Technology Data Exchange (ETDEWEB)

    PHIPPS,GARY S.; KEMME,SHANALYN A.; SWEATT,WILLIAM C.; DESCOUR,M.R.; GARCIA,J.P.; DERENIAK,E.L.

    1999-11-01

    Polarimetry is the method of recording the state of polarization of light. Imaging polarimetry extends this method to recording the spatially resolved state of polarization within a scene. Imaging-polarimetry data have the potential to improve the detection of manmade objects in natural backgrounds. We have constructed a midwave infrared complete imaging polarimeter consisting of a fixed wire-grid polarizer and rotating form-birefringent retarder. The retardance and the orientation angles of the retarder were optimized to minimize the sensitivity of the instrument to noise in the measurements. The optimal retardance was found to be 132{degree} rather than the typical 90{degree}. The complete imaging polarimeter utilized a liquid-nitrogen cooled PtSi camera. The fixed wire-grid polarizer was located at the cold stop inside the camera dewar. The complete imaging polarimeter was operated in the 4.42-5 {micro}m spectral range. A series of imaging experiments was performed using as targets a surface of water, an automobile, and an aircraft. Further analysis of the polarization measurements revealed that in all three cases the magnitude of circular polarization was comparable to the noise in the calculated Stokes-vector components.

  14. Preliminary Observations from the 2014 Sand Dunes Experiment

    Science.gov (United States)

    2014-10-01

    2014 Sand Dunes Experiment by Christopher W. Miller, Ching-Sang Chiu, D. Benjamin Reeder, Ying-Jang Yang, Linus Chiu, and Chi-Fang Chen...COVERED (From-To) June 2014 4. TITLE AND SUBTITLE Preliminary Observations from the 2014 Sand Dunes Experiment 5a. CONTRACT NUMBER 5b. GRANT NUMBER...position of the Department of Defense or the U.S. Government 14. ABSTRACT The Sand Dunes 2014 experiment was international US – Taiwan

  15. Imaging with the leak microstructures: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Baiocchi, C.; Balbinot, G; Battistella, A.; Galeazzi, G.; Lombardi, F.S.; Lombardi, M. E-mail: mariano.lombardi@lnl.infn.it; Prete, G.; Simon, A

    2004-02-01

    We report on some images obtained with the Leak Microstructures (LM), which are elements for the detection of gas ionizing particles based on needle-point anodes. X-ray images of a mask with seven holes, 300 {mu}m in diameter and 100 {mu}m separated, drilled on a tantalum sheet were obtained with a very good spatial resolution. Varying the potential to the drifting electrode we put in evidence the possibility to perform a 'zoom' of the image. X-ray images of a tantalum sheet of about 20x20 mm{sup 2} were obtained using a matrix of 9x9 LMs read by only 6 electronic chains (6 ADCs)

  16. Preliminary results of noise radar experiments

    Science.gov (United States)

    Malanowski, Mateusz; Contartese, Clara; Maslikowski, Lukasz; Baczyk, Marcin; Kulpa, Krzysztof

    2009-06-01

    The paper describes the first results of noise radar experiments carried out at Warsaw University of Technology. The radar system was built with Commercial Off-The-Shelf (COTS) components: log-periodic antennas, an arbitrary waveform generator and a two-channel spectrum analyzer. The radar operated in the continuous-wave mode, and the aim was to detect moving targets in the received signal. The paper shows the system setup as well as the numerical results obtained from the recorded signals.

  17. Metabolic Control with Insulin Pump Therapy: Preliminary Experience

    Directory of Open Access Journals (Sweden)

    Shang-Ren Hsu

    2008-07-01

    Conclusion: Our preliminary experience demonstrated the effectiveness of insulin pump therapy for both type 1 and type 2 diabetic patients. The reduction in their HbA1C values was both statistically and clinically significant. This treatment should be considered for patients poorly controlled by subcutaneous insulin injection therapy.

  18. Preliminary results of the echo-seeding experiment at SLAC

    Energy Technology Data Exchange (ETDEWEB)

    Xiang, D.; Colby, E.; Ding, Y.; Dunning, M.; Frederico, J.; Gilevich, S.; Hast, C.; Jobe, K.; McCormick, D.; Nelson, J.; Raubenheimer, T.O.; Soong, K.; Stupakov, G.; Szalata, Z.; Walz, D.; Weathersby, S.; Woodley, M.; Corlett, J.; Qiang, J.; Penn, G.; Prestemon, S.; Schlueter, R.; Venturini, M.; Wan, W.; Pernet, P-L.

    2010-05-23

    ECHO-7 is a proof-of-principle echo-enabled harmonic generation FEL experiment in the Next Linear Collider Test Accelerator (NLCTA) at SLAC. The experiment aims to generate coherent radiation at 318 nm and 227 nm, which are the 5th and 7th harmonic of the infrared seed laser. In this paper we present the preliminary results from the commissioning run of the completed experimental setup which started in April 2010.

  19. Percutaneous aspiration thromboembolectomy: a preliminary experience.

    Science.gov (United States)

    Murray, J G; Brown, A L; Wilkins, R A

    1994-08-01

    Percutaneous aspiration thromboembolectomy (PAT) is a radiological alternative to surgical embolectomy or thrombolysis in the treatment of acute arterial thromboembolic disease. We report our experience in eight patients aged 63-83 years (mean 71 years). Indications were graft thrombosis (1) or emboli from atrial fibrillation (3), abdominal aneurysm (2) or proximal angioplasty (2). PAT was performed at 10 arterial sites; common iliac (1), profunda femoris (1), superficial femoral (2), femoro-popliteal graft (1), popliteal (2) and arteries of the trifurcation (3). PAT was used as an adjunct to thrombolysis or angioplasty in five patients and as the sole procedure in three patients. It was successful in six patients (seven sites) with mean ABI rising from 0.4 pre- to 0.8 post-procedure. Two of the failures required amputations. One of these was a completely thrombosed dacron femoro-popliteal graft with poor run-off, and the second case had a failed surgical embolectomy prior to amputation. There were no major complications, and no mortality on follow-up at 1 month. PAT is a useful adjunct to thrombolysis and balloon angioplasty in the radiological treatment of acute thromboembolic disease. In patients in whom thrombolysis is contraindicated, it offers an alternative to surgical embolectomy.

  20. Gemini Planet Imager: Preliminary Design Report

    Energy Technology Data Exchange (ETDEWEB)

    Macintosh, B

    2007-05-10

    For the first time in history, direct and indirect detection techniques have enabled the exploration of the environments of nearby stars on scales comparable to the size of our solar system. Precision Doppler measurements have led to the discovery of the first extrasolar planets, while high-contrast imaging has revealed new classes of objects including dusty circumstellar debris disks and brown dwarfs. The ability to recover spectrophotometry for a handful of transiting exoplanets through secondary-eclipse measurements has allowed us to begin to study exoplanets as individual entities rather than points on a mass/semi-major-axis diagram and led to new models of planetary atmospheres and interiors, even though such measurements are only available at low SNR and for a handful of planets that are automatically those most modified by their parent star. These discoveries have galvanized public interest in science and technology and have led to profound new insights into the formation and evolution of planetary systems, and they have set the stage for the next steps--direct detection and characterization of extrasolar Jovian planets with instruments such as the Gemini Planet Imager (GPI). As discussed in Volume 1, the ability to directly detect Jovian planets opens up new regions of extrasolar planet phase space that in turn will inform our understanding of the processes through which these systems form, while near-IR spectra will advance our understanding of planetary physics. Studies of circumstellar debris disks using GPI's polarimetric mode will trace the presence of otherwise-invisible low-mass planets and measure the build-up and destruction of planetesimals. To accomplish the science mission of GPI will require a dedicated instrument capable of achieving contrast of 10{sup -7} or more. This is vastly better than that delivered by existing astronomical AO systems. Currently achievable contrast, about 10{sup -5} at separations of 1 arc second or larger, is

  1. Preliminary results from the MINERvA experiment

    Energy Technology Data Exchange (ETDEWEB)

    Harris, Deborah A.; /Fermilab

    2011-11-01

    The MINERvA experiment, operating since 2009 in the NuMI neutrino beam line at Fermilab, has collected neutrino and antineutrino scattering data on a variety of nuclear targets. The detector is designed to identify events originating in plastic scintillator, lead, carbon, iron, water, and liquid helium. The goal of the experiment is to measure inclusive and exclusive cross sections for neutrino and antineutrino with much greater precision than previous experiments. We present preliminary kinematic distributions for charged current quasi-elastic scattering and other processes.

  2. Preliminary experience on the implementation of computed tomography (CT)-based image guided brachytherapy (IGBT) of cervical cancer using high-dose-rate (HDR) Cobalt-60 source in University of Malaya Medical Centre (UMMC)

    Science.gov (United States)

    Jamalludin, Z.; Min, U. N.; Ishak, W. Z. Wan; Malik, R. Abdul

    2016-03-01

    This study presents our preliminary work of the computed tomography (CT) image guided brachytherapy (IGBT) implementation on cervical cancer patients. We developed a protocol in which patients undergo two Magnetic Resonance Imaging (MRI) examinations; a) prior to external beam radiotherapy (EBRT) and b) prior to intra-cavitary brachytherapy for tumour identification and delineation during IGBT planning and dosimetry. For each fraction, patients were simulated using CT simulator and images were transferred to the treatment planning system. The HR-CTV, IR-CTV, bladder and rectum were delineated on CT-based contouring for cervical cancer. Plans were optimised to achieve HR-CTV and IR-CTV dose (D90) of total EQD2 80Gy and 60Gy respectively, while limiting the minimum dose to the most irradiated 2cm3 volume (D2cc) of bladder and rectum to total EQD2 90Gy and 75Gy respectively. Data from seven insertions were analysed by comparing the volume-based with traditional point- based doses. Based on our data, there were differences between volume and point doses of HR- CTV, bladder and rectum organs. As the number of patients having the CT-based IGBT increases from day to day in our centre, it is expected that the treatment and dosimetry accuracy will be improved with the implementation.

  3. Destination visual image and expectation of experiences

    DEFF Research Database (Denmark)

    Ye, H.; Tussyadiah, Iis

    2011-01-01

    at understanding how a visual image is relevant to the expectation of experiences by deconstructing images of a destination and interpreting visitors' perceptions of these images and the experiences associated with them. The results suggest that tourists with different understandings of desirable experiences found...

  4. A Preliminary Model of Infrared Image Generation for Exhaust Plume

    Directory of Open Access Journals (Sweden)

    Fei Mei

    2011-06-01

    Full Text Available Based on the irradiance calculation of all pixels on the focal plane array, a preliminary infrared imaging prediction model of exhaust plume that have considered the geometrical and the thermal resolution of the camera was developed to understanding the infrared characteristics of exhaust plume. In order to compute the irradiance incident on each pixel, the gas radiation transfer path in the plume for the instantaneous field of view corresponds to the pixel was solved by the simultaneous equation of a enclosure cylinder which covers the exhaust plume and the line of sight. Radiance of the transfer path was calculated by radiation transfer equation for nonscattering gas. The radiative properties of combustion needed in the equation was provided by employing Malkmus model with EM2C narrow band database(25cm-1. The pressure, species concentration along the path was determination by CFD analysis. The relative irradiance intensity of each pixel was converted to color in the display according to gray map coding and hot map coding. Infrared image of the exhaust plumes from a subsonic axisymmetric nozzle with different relative position of camera and the plume was predicted with the model. By changing the parameters, such as FOV and space resolution, the image of different imaging system can be predicted.

  5. Magnetic resonance imaging urodynamics: technique development and preliminary results

    Directory of Open Access Journals (Sweden)

    Gustavo Borghesi

    2006-06-01

    Full Text Available OBJECTIVES: In this preliminary study we report the development of the video urodynamic technique using magnetic resonance imaging (MRI. MATERIALS AND METHODS: We studied 6 women with genuine stress urinary incontinence, diagnosed by history and physical examination. Urodynamic examination was performed on multichannel equipment with the patient in the supine position. Coughing and Valsalva maneuvers were performed at volumes of 150, 250 and 350 mL. Simultaneously, MRI was carried out by using 1.5 T GE Signa CV/i high-speed scanner with real time fluoroscopic imaging possibilities. Fluoroscopic imaging was accomplished in the corresponding planes with T2-weighted single shot fast spin echo sequences at a speed of about 1 frame per second. Both studies were recorded and synchronized, resulting in a single video urodynamic examination. RESULTS: Dynamic MRI with cine-loop reconstruction of 1 image per second demonstrated the movement of all compartment of the relaxed pelvis during straining with the concomitant registration of abdominal and intravesical pressures. In 5 patients, urinary leakage was demonstrated during straining and the Valsalva leak point pressure (VLPP was determined as the vesical pressure at leak subtracted from baseline bladder pressure. Mean VLPP was 72.6 cm H2O (ranging from 43 to 122 cm H2O. CONCLUSIONS: The concept of MRI video urodynamics is feasible. In a clinical perspective, practical aspects represent a barrier to daily use and it should be recommended for research purposes.

  6. The "SCORPION" experiment onboard the International Space Station. Preliminary results.

    Science.gov (United States)

    Borisov, V; Deshevaya, E; Grachov, E; Grigoryan, O; Tchurilo, I; Tsetlin, V

    2003-01-01

    The "SCORPION" program onboard the Russian Segment (RS) of the International Space Station (ISS) is designed to carry out complex research of the effects of the nar-Earth space parameters on the conditions under which various experiments and operations are being conducted. Special attention in this program was paid to the biological objects onboard the orbital station, e.g. it was found that variation in the number of colony forming units (micromicets and bacteria) correlates with the solar activity and the absorbed dose. The "SCORPION" experiment onboard the RS ISS started in January 2002. It was designed to measure the following parameters inside the space absorbed doses in different places inside the RS ISS, the fluxes of energetic charged particles, neutrons and gamma-quanta; the vectors of the magnetic field and low-frequency electromagnetic waves. At the same time the growth of micromicets on the samples of various materials was studied. The description of the "SCORPION" experiment and the preliminary results obtained onboard the RS ISS in 2002 are presented.

  7. Calibration Study and Preliminary Results of PRad Experiment

    Science.gov (United States)

    Levillain, Maxime; PRad Collaboration

    2016-09-01

    The latest measurements of the proton radius through muonic hydrogen Lamb shift show a discrepancy of 7 σ from a global analysis of standard hydrogen Lamb shift and elastic ep -scattering. In order to understand this proton radius puzzle, the PRad experiment successfully took in last June some elastic ep -scattering data at very low Q2 (2 .10-4 to 10-1 GeV2) with very accurate angle and energy measurements to minimize the systematic uncertainties. Before measuring the cross-sections that will be used to extract the electromagnetic form factor GE(Q2) and the proton radius, a very careful calibration of the electromagnetic calorimeter (HyCal) must be performed to get a good energy resolution and separate ep -events from M øller events especially at low angle. We will present an extended study of the electromagnetic calorimeter calibration of this experiment as well as some preliminary results on ep - and ee -scattering processes extracted from the data. The PRad experiment is supported in part by NSF MRI Award PHY-1229153.

  8. Design, integration and preliminary results of the IXV Catalysis experiment

    Science.gov (United States)

    Viladegut, Alan; Panerai, F.; Chazot, O.; Pichon, T.; Bertrand, P.; Verdy, C.; Coddet, C.

    2016-08-01

    The CATalytic Experiment (CATE) is an in-flight demonstration of catalysis effects at the surface of thermal protection materials. A high-catalytic coating was applied over the baseline ceramic material on the windward side of the intermediate experimental vehicle (IXV). The temperature jump due to different catalytic activities was detected during re-entry through measurements made with near-surface thermocouples on the windward side of the vehicle. The experiment aimed at contributing to the development and validation of gas/surface interaction models for re-entry applications. The present paper summarizes the design of CATE and its integration on the windward side of the IXV. Results of a qualification campaign at the Plasmatron facility of the von Karman Institute for Fluid Dynamics are presented. They provided an experimental evidence of the temperature jump at the low-to-high catalytic interface of the heat shield under aerothermal conditions relevant to the actual IXV flight. These tests also gave confidence so that the high-catalytic patch would not endanger the integrity of the vehicle and the safety of the mission. A preliminary assessment of flight data from the thermocouple measurements shows consistency with results of the qualification tests.

  9. Investigation of fracture-matrix interaction: Preliminary experiments in a simple system

    Energy Technology Data Exchange (ETDEWEB)

    Foltz, S.D. [New Mexico Univ., Albuquerque, NM (United States). Dept. of Physics and Astronomy; Tidwell, V.C.; Glass, R.J.; Sobolik, S.R. [Sandia National Labs., Albuquerque, NM (United States)

    1992-12-31

    Paramount to the modeling of unsaturated flow and transport through fractured porous media is a clear understanding of the processes controlling fracture-matrix interaction. As a first step toward such an understanding, two preliminary experiments have been performed to investigate the influence of matrix imbibition on water percolation through unsaturated fractures in the plane normal to the fracture. Test systems consisted of thin slabs of either tuff or an analog material cut by a single vertical fracture into which a constant fluid flux was introduced. Transient moisture content and solute concentration fields were imaged by means of x-ray absorption. Flow fields associated with the two different media were significantly different owing to differences in material properties relative to the imposed flux. Richards` equation was found to be a valid means of modeling the imbibition of water into the tuff matrix from a saturated fracture for the current experiment.

  10. The Galileo Solid-State Imaging experiment

    Science.gov (United States)

    Belton, Michael J. S.; Klaasen, Kenneth P.; Clary, Maurice C.; Anderson, James L.; Anger, Clifford D.; Carr, Michael H.; Chapman, Clark R.; Davies, Merton E.; Greeley, Ronald; Anderson, Donald

    1992-01-01

    The Galileo Orbiter's Solid-State Imaging (SSI) experiment uses a 1.5-m focal length TV camera with 800 x 800 pixel, virtual-phase CCD detector in order to obtain images of Jupiter and its satellites which possess a combination of sensitivity levels, spatial resolutions, geometric fidelity, and spectral range that are unmatched by earlier imaging data. After describing the performance of this equipment on the basis of ground calibrations, attention is given to the SSI experiment's Jupiter system observation objectives; these encompass atmospheric science, satellite surfaces, ring structure, and 'darkside' experiments.

  11. Prospectively gated axial CT coronary angiography: preliminary experiences with a novel low-dose technique

    Energy Technology Data Exchange (ETDEWEB)

    Klass, Oliver; Jeltsch, Martin; Feuerlein, Sebastian; Brunner, Horst; Brambs, Hans-Juergen; Hoffmann, Martin H.K. [University Hospital of Ulm, Department of Diagnostic and Interventional Radiology, Ulm (Germany); Nagel, Hans-Dieter [Philips Healthcare, Department of Science and Technology, Hamburg (Germany); Walker, Matthew J. [CT Clinical Science, Philips Healthcare, Cleveland, OH (United States)

    2009-04-15

    To assess image quality and radiation exposure with prospectively gated axial CT coronary angiography (PGA) compared to retrospectively gated helical techniques (RGH). Forty patients with suspected coronary artery disease (CAD) and a stable heart rate below 65 bpm underwent CT coronary angiography (CTCA) using a 64-channel CT system. The patient cohort consisted of 20 consecutive patients examined using a PGA technique and 20 patients examined using a standard RGH technique. Both groups were matched demographically according to age, gender, body mass index, and heart rate. For both groups, two independent observers assessed image quality for all coronary segments on an ordinal scale from 1 (nonassessable) to 5 (excellent quality). Image quality and radiation exposure were compared between patient groups. There were no significant differences in vessel-based image quality between the two groups (P > 0.05). Mean ({+-} SD) effective radiation exposure in the PGA group was 3.7 {+-} 0.8 mSv compared to 18.9 {+-} 3.8 mSv in the RGH group without ECG-based tube current modulation (P < 0.001). Preliminary experience shows PGA technique to be a promising approach for CTCA resulting in a substantial reduction in radiation exposure with image quality comparable to that of standard RGH technique. (orig.)

  12. Preliminary results of the XR2-1 experiment

    Energy Technology Data Exchange (ETDEWEB)

    Gauntt, R.O.; Helmick, P.H. [Sandia National Labs., Albuquerque, NM (United States); Humphries, L. [SAIC, Albuquerque, NM (United States)

    1996-03-01

    The XR2-1 (Ex-Reactor) experiment, investigating metallic core-melt relocation in boiling water reactor geometry, was performed on October 12, 1995, following two previous simpler XR1-series tests in August and November of 1993. The XR2-1 test made use of a highly detailed replication of the lower region of the BWR core, including the control blade and channel box structures, fuel rods, fuel canister nosepieces, control blade velocity limiter, and fuel support pieces, in order to investigate a key core melt progression uncertainty for BWR Station Blackout type accidents. The purpose of this experiment program is to examine the behavior of downward-draining molten metallic core materials in a severe reactor accident in a dry BWR core, and to determine conditions under which the molten materials drain out of the core region, or freeze to form blockages in the lower portion of the core. In the event that the draining metallic materials do not form stable blockages in the lower core region, and instead erode the lower core structures such as the lower core plate, then the subsequent core melt progression processes may proceed quite differently than was observed in the TMI-2 accident, with correspondingly different impact on vessel loading and vessel release behavior. The results of the Ex-Reactor tests are preliminary. All of the tests conducted have shown a significant degree of channel box destruction induced by the draining control blade materials. The XR2-1 test further showed that the draining zircaloy melt causes significant disruption of the fuel rod geometry. All of the tests have shown tendencies to form interim blockages as the melts temporarily freeze, but that these blockages re-melt, assisted by eutectic interactions, resulting in the sudden draining of accumulated metallic melt pools.

  13. Simultaneous whole body 18F-fluorodeoxyglucose positron emission tomography magnetic resonance imaging for evaluation of pediatric cancer: Preliminary experience and comparison with 18F-fluorodeoxyglucose positron emission tomography computed tomogra

    Institute of Scientific and Technical Information of China (English)

    Brian S Pugmire; Alexander R Guimaraes; Ruth Lim; Alison M Friedmann; Mary Huang; David Ebb; Howard Weinstein; Onofrio A Catalano; Umar Mahmood; Ciprian Catana; Michael S Gee

    2016-01-01

    AIM: To describe our preliminary experience with simultaneous whole body 18F-fluorodeoxyglucose(18F-FDG)positron emission tomography and magnetic resonance imaging(PET-MRI) in the evaluation of pediatric oncology patients.METHODS: This prospective, observational, singlecenter study was Health Insurance Portability and Accountability Act-compliant, and institutional review board approved. To be eligible, a patient was required to:(1) have a known or suspected cancer diagnosis;(2) be under the care of a pediatric hematologist/oncologist; and(3) be scheduled for clinically indicated 18F-FDG PETCT examination at our institution. Patients underwent PET-CT followed by PET-MRI on the same day. PET-CT examinations were performed using standard department protocols. PET-MRI studies were acquired with an integrated 3 Tesla PET-MRI scanner using whole body T1 Dixon, T2 HASTE, EPI diffusion-weighted imaging(DWI) and STIR sequences. No additional radiotracer was given for the PET-MRI examination. Both PET-CT and PETMRI examinations were reviewed by consensus by two study personnel. Test performance characteristics of PETMRI, for the detection of malignant lesions, including FDG maximum standardized uptake value(SUVmax) and minimum apparent diffusion coefficient(ADCmin), were calculated on a per lesion basis using PET-CT as a reference standard.RESULTS: A total of 10 whole body PET-MRI exams were performed in 7 pediatric oncology patients. The mean patient age was 16.1 years(range 12-19 years) including 6 males and 1 female. A total of 20 malignant and 21 benign lesions were identified on PET-CT. PET-MRI SUVmax had excellent correlation with PET-CT SUVmax for both benign and malignant lesions(R = 0.93). PETMRI SUVmax > 2.5 had 100% accuracy for discriminating benign from malignant lesions using PET-computed tomography(CT) reference. Whole body DWI was also evaluated: the mean ADCmin of malignant lesions(780.2 + 326.6) was significantly

  14. Analyzing and mining automated imaging experiments.

    Science.gov (United States)

    Berlage, Thomas

    2007-04-01

    Image mining is the application of computer-based techniques that extract and exploit information from large image sets to support human users in generating knowledge from these sources. This review focuses on biomedical applications of this technique, in particular automated imaging at the cellular level. Due to increasing automation and the availability of integrated instruments, biomedical users are becoming increasingly confronted with the problem of analyzing such data. Image database applications need to combine data management, image analysis and visual data mining. The main point of such a system is a software layer that represents objects within an image and the ability to use a large spectrum of quantitative and symbolic object features. Image analysis needs to be adapted to each particular experiment; therefore, 'end user programming' will be desired to make the technology more widely applicable.

  15. Preliminary results of equation of state measurements using imaging x-ray Thomson spectrometer

    Science.gov (United States)

    Belancourt, Patrick; Theobald, Wolfgang; Keiter, Paul; Collins, Timothy; Bonino, Mark; Kozlowski, Pawel; Drake, Paul; University of Michigan Team; LaboratoryLaser Energetics Team; University of Oxford Team

    2014-10-01

    Understanding the equation of state of materials under shocked conditions is important for laboratory astrophysics and high-energy-density physics experiments. The goal of the experiments discussed here is to create a platform for equation of state measurements in shocked foams on Omega EP. The target of interest for these experiments is shocked carbonized resorcinol formaldehyde foam with an initial density of 0.34 g/cc. Lasers irradiate an ablator, driving a shock into the foam. Plasma conditions ahead of the shock, at the shock and behind the shock are diagnosed using the imaging x-ray Thomson spectrometer (IXTS). The IXTS is capable of spectrally resolving the scattered x-ray beam while imaging in one spatial dimension. Preliminary results from these experiments will be shown. This work is funded by the U.S. Department of Energy, through the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, grant number DE-NA0001840, and the National Laser User Facility Program, Grant Number DE-NA0000850, and through the Laboratory for Laser Energetics, University of Rochester by the NNSA/OICF under Cooperative Agreement No. DE-FC52-08NA28302.

  16. Modeling method and preliminary model of Asteroid Toutatis from Chang'E-2 optical images

    Science.gov (United States)

    Li, Xiang-Yu; Qiao, Dong

    2014-06-01

    Shape modeling is fundamental to the analysis of dynamic environment and motion around asteroid. Chang'E-2 successfully made a flyby of Asteroid 4179 Toutatis and obtained plenty of high-resolution images during the mission. In this paper, the modeling method and preliminary model of Asteroid Toutatis are discussed. First, the optical images obtained by Chang'E-2 are analyzed. Terrain and silhouette features in images are described. Then, the modeling method based on previous radar model and preliminary information from optical images is proposed. A preliminary polyhedron model of Asteroid Toutatis is established. Finally, the spherical harmonic coefficients of Asteroid Toutatis based on the polyhedron model are obtained. Some parameters of model are analyzed and compared. Although the model proposed in this paper is only a preliminary model, this work offers a valuable reference for future high-resolution models.

  17. Preliminary experience with laparoscopic cholecystectomy in a nigerian teaching hospital.

    Science.gov (United States)

    Afuwape, O O; Akute, O O; Adebanjo, A T

    2012-01-01

    Presently many centers have facilities for laparoscopic surgery in Nigeria, but the practice is just evolving in most of these centers. This article presents the preliminary experience of the endoscopic surgery unit (general surgery) at the University College Hospital Ibadan Nigeria. The University College Hospital is the premier Nigerian teaching hospital and is located in the south-western part of the country. All the patients who had laparoscopic cholecystectomy at the University College Hospital between June 2009 and January 2011 were included in this study. The patients' demographic data, diagnosis, results of investigations and intra-operative findings were obtained from the records. Additional information extracted from the records was the duration of surgery, complications, outcome and discharge periods. There were thirteen patients over the twenty month period consisting of twelve females and one male. The age range was twenty six to sixty seven years with a mean of 44.6 years. The duration of surgery ranged from 90 to 189 minutes with a mean of 124 minutes. There were two complications. These were adhesive bowel obstruction and common bile duct injury. The duration of admission ranged from four to thirty two days with a mean of 7.53SD ± 8.5 days. There was one conversion to open surgery due to intra-operative gallbladder perforation with consequent dispersal of multiple gall stones within the peritoneal cavity. The common bile duct injury was diagnosed four days following surgery for which a choledochojejunostomy was done after initial conservative treatment. There was no mortality. Laparoscopic surgery is feasible in Nigeria and is likely to show increasing popularity among patients and surgeons. A careful patient selection protocol is necessary for an acceptable success rate with minimal complications. Our protocol of patient selection eliminated the need for intra-operative common bile duct exploration which requires expensive instruments. However, to

  18. Preliminary Design of a Pendulum Experiment for Searching for a Lorentz-Violation Signal

    CERN Document Server

    Shao, Cheng-Gang; Tan, Yu-Jie

    2016-01-01

    This work mainly presents a preliminary design for a pendulum experiment with both the source mass and the test mass in a striped pattern to amplify the Lorentz-violation signal, since the signal is sensitive to edge effects.

  19. Preliminary experiments on pharmacokinetic diffuse fluorescence tomography of CT-scanning mode

    Science.gov (United States)

    Zhang, Yanqi; Wang, Xin; Yin, Guoyan; Li, Jiao; Zhou, Zhongxing; Zhao, Huijuan; Gao, Feng; Zhang, Limin

    2016-10-01

    In vivo tomographic imaging of the fluorescence pharmacokinetic parameters in tissues can provide additional specific and quantitative physiological and pathological information to that of fluorescence concentration. This modality normally requires a highly-sensitive diffuse fluorescence tomography (DFT) working in dynamic way to finally extract the pharmacokinetic parameters from the measured pharmacokinetics-associated temporally-varying boundary intensity. This paper is devoted to preliminary experimental validation of our proposed direct reconstruction scheme of instantaneous sampling based pharmacokinetic-DFT: A highly-sensitive DFT system of CT-scanning mode working with parallel four photomultiplier-tube photon-counting channels is developed to generate an instantaneous sampling dataset; A direct reconstruction scheme then extracts images of the pharmacokinetic parameters using the adaptive-EKF strategy. We design a dynamic phantom that can simulate the agent metabolism in living tissue. The results of the dynamic phantom experiments verify the validity of the experiment system and reconstruction algorithms, and demonstrate that system provides good resolution, high sensitivity and quantitativeness at different pump speed.

  20. A Preliminary Comparison of Three Dimensional Particle Tracking and Sizing using Plenoptic Imaging and Digital In-line Holography

    Energy Technology Data Exchange (ETDEWEB)

    Guildenbecher, Daniel Robert; Munz, Elise Dahnke; Farias, Paul Abraham; Thurow, Brian S [Auburn U

    2015-12-01

    Digital in-line holography and plenoptic photography are two techniques for single-shot, volumetric measurement of 3D particle fields. Here we present a preliminary comparison of the two methods by applying plenoptic imaging to experimental configurations that have been previously investigated with digital in-line holography. These experiments include the tracking of secondary droplets from the impact of a water drop on a thin film of water and tracking of pellets from a shotgun. Both plenoptic imaging and digital in-line holography successfully quantify the 3D nature of these particle fields. This includes measurement of the 3D particle position, individual particle sizes, and three-component velocity vectors. For the initial processing methods presented here, both techniques give out-of-plane positional accuracy of approximately 1-2 particle diameters. For a fixed image sensor, digital holography achieves higher effective in-plane spatial resolutions. However, collimated and coherent illumination makes holography susceptible to image distortion through index of refraction gradients, as demonstrated in the shotgun experiments. On the other hand, plenotpic imaging allows for a simpler experimental configuration. Furthermore, due to the use of diffuse, white-light illumination, plenoptic imaging is less susceptible to image distortion in the shotgun experiments. Additional work is needed to better quantify sources of uncertainty, particularly in the plenoptic experiments, as well as develop data processing methodologies optimized for the plenoptic measurement.

  1. Smart Ultrasound Remote Guidance Experiment (SURGE) Preliminary Findings

    Science.gov (United States)

    Hurst, Victor; Dulchavsky, Scott; Garcia, Kathleen; Sargsyan, Ashot; Ebert, Doug

    2009-01-01

    To date, diagnostic quality ultrasound images were obtained aboard the International Space Station (ISS) using the ultrasound of the Human Research Facility (HRF) rack in the Laboratory module. Through the Advanced Diagnostic Ultrasound in Microgravity (ADUM) and the Braslet-M Occlusion Cuffs (BRASLET SDTO) studies, non-expert ultrasound operators aboard the ISS have performed cardiac, thoracic, abdominal, vascular, ocular, and musculoskeletal ultrasound assessments using remote guidance from ground-based ultrasound experts. With exploration class missions to the lunar and Martian surfaces on the horizon, crew medical officers will necessarily need to operate with greater autonomy given communication delays (round trip times of up to 5 seconds for the Moon and 90 minutes for Mars) and longer periods of communication blackouts (due to orbital constraints of communication assets). The SURGE project explored the feasibility and training requirements of having non-expert ultrasound operators perform autonomous ultrasound assessments in a simulated exploration mission outpost. The project aimed to identify experience, training, and human factors requirements for crew medical officers to perform autonomous ultrasonography. All of these aims pertained to the following risks from the NASA Bioastronautics Road Map: 1) Risk 18: Major Illness and Trauna; 2) Risk 20) Ambulatory Care; 3) Risk 22: Medical Informatics, Technologies, and Support Systems; and 4) Risk 23: Medical Skill Training and Maintenance.

  2. Preliminary In-Vivo Evaluation of Convex Array Synthetic Aperture Imaging

    DEFF Research Database (Denmark)

    Pedersen, Morten Høgholm; Gammelmark, Kim; Jensen, Jørgen Arendt

    2004-01-01

    of STA imaging in comparison to conventional imaging. The purpose is to evaluate whether STA imaging is feasible in-vivo. and whether the image quality obtained is comparable to traditional scanned imaging in terms of penetration depth, spatial resolution, contrast resolution, and artifacts. Acquisition...... using randomized blinded presentation. Penetration and image quality were scored and evaluated statistically. Results show that in-vivo imaging using STA imaging is feasible with improved image quality compared to conventional imaging.......Synthetic transmit aperture (STA) imaging has previously been investigated and compared to traditional imaging techniques in simulations and phantom studies. However, a full in-vivo study evaluating its clinical potential has yet to be conducted. This paper presents a preliminary in-vivo study...

  3. Effect of oxygen manipulations on benthic foraminifera: A preliminary experiment

    Digital Repository Service at National Institute of Oceanography (India)

    Panchang, R.; Nigam, R.; Linshy, V.; Rana, S.S.; Ingole, B.S.

    marine protists, which have a great potential to detect ecological stress at a very early stage. Due to their high fossilization potential, an understanding of the ecology of foraminifera allows interpretations of the past benthic environmental...’. Many soft-shelled forms also exist, but have not been considered in the present study as they have no fossilization potential and thereby of no geological significance. This is a preliminary report and only presents the effect of oxygen...

  4. Preliminary Experiments with XKaapi on Intel Xeon Phi Coprocessor

    OpenAIRE

    Ferreira Lima, Joao Vicente; Broquedis, Francois; Gautier, Thierry; Raffin, Bruno

    2013-01-01

    International audience; This paper presents preliminary performance comparisons of parallel applications developed natively for the Intel Xeon Phi accelerator using three different parallel programming environments and their associated runtime systems. We compare Intel OpenMP, Intel CilkPlus and XKaapi together on the same benchmark suite and we provide comparisons between an Intel Xeon Phi coprocessor and a Sandy Bridge Xeon-based machine. Our benchmark suite is composed of three computing k...

  5. A preliminary diffusional kurtosis imaging study of Parkinson disease: comparison with conventional diffusion tensor imaging

    Energy Technology Data Exchange (ETDEWEB)

    Kamagata, Koji; Kamiya, Kouhei; Suzuki, Michimasa; Hori, Masaaki; Yoshida, Mariko; Aoki, Shigeki [Juntendo University School of Medicine, Department of Radiology, Bunkyo-ku, Tokyo (Japan); Tomiyama, Hiroyuki; Hatano, Taku; Motoi, Yumiko; Hattori, Nobutaka [Juntendo University School of Medicine, Department of Neurology, Tokyo (Japan); Abe, Osamu [Nihon University School of Medicine, Department of Radiology, Tokyo (Japan); Shimoji, Keigo [National Center of Neurology and Psychiatry Hospital, Department of Radiology, Tokyo (Japan)

    2014-03-15

    Diffusional kurtosis imaging (DKI) is a more sensitive technique than conventional diffusion tensor imaging (DTI) for assessing tissue microstructure. In particular, it quantifies the microstructural integrity of white matter, even in the presence of crossing fibers. The aim of this preliminary study was to compare how DKI and DTI show white matter alterations in Parkinson disease (PD). DKI scans were obtained with a 3-T magnetic resonance imager from 12 patients with PD and 10 healthy controls matched by age and sex. Tract-based spatial statistics were used to compare the mean kurtosis (MK), mean diffusivity (MD), and fractional anisotropy (FA) maps of the PD patient group and the control group. In addition, a region-of-interest analysis was performed for the area of the posterior corona radiata and superior longitudinal fasciculus (SLF) fiber crossing. FA values in the frontal white matter were significantly lower in PD patients than in healthy controls. Reductions in MK occurred more extensively throughout the brain: in addition to frontal white matter, MK was lower in the parietal, occipital, and right temporal white matter. The MK value of the area of the posterior corona radiata and SLF fiber crossing was also lower in the PD group. DKI detects changes in the cerebral white matter of PD patients more sensitively than conventional DTI. In addition, DKI is useful for evaluating crossing fibers. By providing a sensitive index of brain pathology in PD, DKI may enable improved monitoring of disease progression. (orig.)

  6. AGC-1 Experiment and Final Preliminary Design Report

    Energy Technology Data Exchange (ETDEWEB)

    Robert L. Bratton; Tim Burchell

    2006-08-01

    This report details the experimental plan and design as of the preliminary design review for the Advanced Test Reactor Graphite Creep-1 graphite compressive creep capsule. The capsule will contain five graphite grades that will be irradiated in the Advanced Test Reactor at the Idaho National Laboratory to determine the irradiation induced creep constants. Seven other grades of graphite will be irradiated to determine irradiated physical properties. The capsule will have an irradiation temperature of 900 C and a peak irradiation dose of 5.8 x 10{sup 21} n/cm{sup 2} [E > 0.1 MeV], or 4.2 displacements per atom.

  7. The Ring Imaging Cherenkov detector (RICH) of the AMS experiment

    CERN Document Server

    Barão, F; Alcaraz, J; Arruda, L; Barrau, A; Barreira, G; Belmont, E; Berdugo, J; Brinet, M; Buénerd, M; Casadei, D; Casaus, J; Cortina, E; Delgado, C; Díaz, C; Derome, L; Eraud, L; Garcia-Lopez, R J; Gallin-Martel, L; Giovacchini, F; Gonçalves, P; Lanciotti, E; Laurenti, G; Malinine, A; Maña, C; Marin, J; Martínez, G; Menchaca-Rocha, A; Molla, M; Palomares, C; Panniello, M; Pereira, R; Pimenta, M; Protasov, K; Sánchez, E; Seo, E S; Sevilla, N; Torrento, A; Vargas-Trevino, M; Veziant, O

    2006-01-01

    The Alpha Magnetic Spectrometer (AMS) experiment to be installed on the International Space Station (ISS) will be equipped with a proximity focusing Ring Imaging Cherenkov (RICH) detector for measuring the electric charge and velocity of the charged cosmic particles. A RICH prototype consisting of 96 photomultiplier units, including a piece of the conical reflector, was built and its performance evaluated with ion beam data. Preliminary results of the in-beam tests performed with ion fragments resulting from collisions of a 158 GeV/c/nuc primary beam of Indium ions (CERN SPS) on a Pb target are reported. The collected data included tests to the final front-end electronics and to different aerogel radiators. Cherenkov rings for a large range of charged nuclei and with reflected photons were observed. The data analysis confirms the design goals. Charge separation up to Fe and velocity resolution of the order of 0.1% for singly charged particles are obtained.

  8. Preliminary results of the scientific experiments on the Kosmos-936 biosatellite

    Science.gov (United States)

    1977-01-01

    The scientific equipment and experiments on the Kosmos-936 biosatellite are described, including various ground controls and the lab unit for studies at the descent vehicle landing site. Preliminary results are presented of the physiological experiment with rats, biological experiments with drosophila and higher and lower plants, and radiation physics and radiobiology studies for the planning of biological protection on future space flights. The most significant conclusion from the preliminary data is that rats tolerate space flight better with an artificial force of gravity.

  9. Zero-gravity cloud physics laboratory: Experiment program definition and preliminary laboratory concept studies

    Science.gov (United States)

    Eaton, L. R.; Greco, E. V.

    1973-01-01

    The experiment program definition and preliminary laboratory concept studies on the zero G cloud physics laboratory are reported. This program involves the definition and development of an atmospheric cloud physics laboratory and the selection and delineations of a set of candidate experiments that must utilize the unique environment of zero gravity or near zero gravity.

  10. Interactions between piscivores, zooplanktivores and zooplankton in submerged macrophytes : Preliminary observations from enclosure and pond experiments

    DEFF Research Database (Denmark)

    Jacobsen, Lene; Perrow, M.R.; Landkildehus, F.

    1997-01-01

    behavioural changes of zooplanktivores has received little attention, even though this may be an important mechanism in enhancing the stability of submerged macrophytes in shallow lakes. Preliminary observations from an unreplicated large-scale field enclosure experiment and a replicated pond experiment...

  11. Preliminary Studies for Three Experiments at Treiman-Yang Criterion

    Science.gov (United States)

    Kres, I. V.; Kondratyev, V. N.; Cherubini, S.; Spitaleri, C.

    2016-05-01

    Nuclear reactions with three bodies in their final state may proceed through different reaction mechanisms. The Feynman graph technique has been widely used to describe such reactions. However, it is very difficult in general to select the graphs that dominate in given process. The Treiman-Yang criterion is one of the most powerful experimental tests for verifying the pole approximation prediction when describing a quasi-free reaction mechanism. We propose the theoretical study of the H2(B10, α Be7)ns, H1(B11, α1α2)αs, He3(Be9, α1α2)αs reactions at different energies. The preliminary study helps to check the existence of a QF channel by using the TY creterion.

  12. Preliminary comparison of 3D synthetic aperture imaging with Explososcan

    DEFF Research Database (Denmark)

    Rasmussen, Morten Fischer; Hansen, Jens Munk; Ferin, Guillaume

    2012-01-01

    Explososcan is the 'gold standard' for real-time 3D medical ultrasound imaging. In this paper, 3D synthetic aperture imaging is compared to Explososcan by simulation of 3D point spread functions. The simulations mimic a 32x32 element prototype transducer. The transducer mimicked is a dense matrix...

  13. Preliminary results from the {sup 51}Cr neutrino source experiment in GALLEX

    Energy Technology Data Exchange (ETDEWEB)

    Hampel, W.; Heusser, G.; Kiko, J. [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany)] [and others

    1996-09-01

    The GALLEX collaboration performed a second {sup 51}Cr neutrino source experiment during fall 1995. The full results from this second source experiment will not be available before the end of 1996. Meanwhile, we present a short description and preliminary results in this informal note. The (preliminary) value of the activity obtained form direct measurements has been found equal to (68.7 {+-}0.7) PBq (with 1-sigma error). This value, which is about 10% higher than the activity of the first source, was achieved by optimizing the irradiation conditions in the Silo{acute e} reactor and doing a longer irradiation of the enriched chromium. Preliminary results show that the ratio, R, of the radiochemically determined activity from {sup 71}Ge counting (57.1 {+-} PBq) to the directly measured activity is (0.83 {+-} 0.10). The combined value of R for the two source experiments is (0.92 {+-} 0.08).

  14. Kinetics experiments and bench-scale system: Background, design, and preliminary experiments

    Energy Technology Data Exchange (ETDEWEB)

    Rofer, C.K.

    1987-10-01

    The project, Supercritical Water Oxidation of Hazardous Chemical Waste, is a Hazardous Waste Remedial Actions Program (HAZWRAP) Research and Development task being carried out by the Los Alamos National Laboratory. Its objective is to obtain information for use in understanding the basic technology and for scaling up and applying oxidation in supercritical water as a viable process for treating a variety of DOE-DP waste streams. This report gives the background and rationale for kinetics experiments on oxidation in supercritical water being carried out as a part of this HAZWRAP Research and Development task. It discusses supercritical fluid properties and their relevance to applying this process to the destruction of hazardous wastes. An overview is given of the small emerging industry based on applications of supercritical water oxidation. Factors that could lead to additional applications are listed. Modeling studies are described as a basis for the experimental design. The report describes plug flow reactor and batch reactor systems, and presents preliminary results. 28 refs., 4 figs., 5 tabs.

  15. Preliminary comparison of 3D synthetic aperture imaging with Explososcan

    Science.gov (United States)

    Rasmussen, Morten Fischer; Hansen, Jens Munk; Férin, Guillaume; Dufait, Rémi; Jensen, Jørgen Arendt

    2012-03-01

    Explososcan is the 'gold standard' for real-time 3D medical ultrasound imaging. In this paper, 3D synthetic aperture imaging is compared to Explososcan by simulation of 3D point spread functions. The simulations mimic a 32×32 element prototype transducer. The transducer mimicked is a dense matrix phased array with a pitch of 300 μm, made by Vermon. For both imaging techniques, 289 emissions are used to image a volume spanning 60° in both the azimuth and elevation direction and 150mm in depth. This results for both techniques in a frame rate of 18 Hz. The implemented synthetic aperture technique reduces the number of transmit channels from 1024 to 256, compared to Explososcan. In terms of FWHM performance, was Explososcan and synthetic aperture found to perform similar. At 90mm depth is Explososcan's FWHM performance 7% better than that of synthetic aperture. Synthetic aperture improved the cystic resolution, which expresses the ability to detect anechoic cysts in a uniform scattering media, at all depths except at Explososcan's focus point. Synthetic aperture reduced the cyst radius, R20dB, at 90mm depth by 48%. Synthetic aperture imaging was shown to reduce the number of transmit channels by four and still, generally, improve the imaging quality.

  16. The Galileo Solid-State Imaging experiment

    Science.gov (United States)

    Belton, M.J.S.; Klaasen, K.P.; Clary, M.C.; Anderson, J.L.; Anger, C.D.; Carr, M.H.; Chapman, C.R.; Davies, M.E.; Greeley, R.; Anderson, D.; Bolef, L.K.; Townsend, T.E.; Greenberg, R.; Head, J. W.; Neukum, G.; Pilcher, C.B.; Veverka, J.; Gierasch, P.J.; Fanale, F.P.; Ingersoll, A.P.; Masursky, H.; Morrison, D.; Pollack, James B.

    1992-01-01

    The Solid State Imaging (SSI) experiment on the Galileo Orbiter spacecraft utilizes a high-resolution (1500 mm focal length) television camera with an 800 ?? 800 pixel virtual-phase, charge-coupled detector. It is designed to return images of Jupiter and its satellites that are characterized by a combination of sensitivity levels, spatial resolution, geometric fiedelity, and spectral range unmatched by imaging data obtained previously. The spectral range extends from approximately 375 to 1100 nm and only in the near ultra-violet region (??? 350 nm) is the spectral coverage reduced from previous missions. The camera is approximately 100 times more sensitive than those used in the Voyager mission, and, because of the nature of the satellite encounters, will produce images with approximately 100 times the ground resolution (i.e., ??? 50 m lp-1) on the Galilean satellites. We describe aspects of the detector including its sensitivity to energetic particle radiation and how the requirements for a large full-well capacity and long-term stability in operating voltages led to the choice of the virtual phase chip. The F/8.5 camera system can reach point sources of V(mag) ??? 11 with S/N ??? 10 and extended sources with surface brightness as low as 20 kR in its highest gain state and longest exposure mode. We describe the performance of the system as determined by ground calibration and the improvements that have been made to the telescope (same basic catadioptric design that was used in Mariner 10 and the Voyager high-resolution cameras) to reduce the scattered light reaching the detector. The images are linearly digitized 8-bits deep and, after flat-fielding, are cosmetically clean. Information 'preserving' and 'non-preserving' on-board data compression capabilities are outlined. A special "summation" mode, designed for use deep in the Jovian radiation belts, near Io, is also described. The detector is 'preflashed' before each exposure to ensure the photometric linearity

  17. Diffusion-weighted MR imaging of cystic lesions of neurocysticercosis: a preliminary study

    Energy Technology Data Exchange (ETDEWEB)

    Raffin, Luciana S.; Bacheschi, Luiz A.; Machado, Luis R.; Nobrega, Jose P.S.; Coelho, Christina; Leite, Claudia C. [Sao Paulo Univ., SP (Brazil). Faculdade de Medicina. Dept. de Neurologia]. E-mail: bacheschi@henet.usp.br

    2001-12-01

    Neurocysticercosis is an endemic disease in some developing countries. It has pleomorfic clinical and imaging findings, which are variable from patient to patient. In this preliminary note, we studied the magnetic resonance diffusion-weighted images of sixteen patients presenting with cystic lesions of this disease diagnosed by clinical and laboratorial findings. All the lesions had hypointense signal and the similar apparent diffusion coefficient values as the cerebrospinal fluid. (author)

  18. Optical fiber sensors for image formation in radiodiagnostic - preliminary essays; Sensores a fibra optica para formacao de imagens em radiodiagnostico - ensaios preliminares

    Energy Technology Data Exchange (ETDEWEB)

    Carvalho, Cesar C. de; Werneck, Marcelo M. [Universidade Federal, Rio de Janeiro, RJ (Brazil). Coordenacao dos Programas de Pos-graduacao de Engenharia. Programa de Engenharia Biomedica

    1998-07-01

    This work describes preliminary experiments that will bring subsidies to analyze the capability to implement a system able to capture radiological images with new sensor system, comprised by FOs scanning process and I-CCD camera. These experiments have the main objective to analyze the optical response from FOs bundle, with several typos of scintillators associated with them, when it is submitted to medical x-rays exposition. (author)

  19. Preliminary Experiments on the Propagation of Plastic Deformation

    Science.gov (United States)

    2013-04-25

    Burnh:l.m Kelly Assist:J.nt to the Chief 2 Defense and Offense • • .. , . R E _S __ 1 RIC TED ., Preface ’ . The work described ~n this...variance with t he t heoreticall ;J- obta i ned curves and , hence, needs f~ther explanation. The object of the experiment s des cribed in t hi s...quite well with the experiments . The shape of t he pl3.stic wave is at some variance with the theor et i cally obta i ned curves. A.s shown by

  20. HDlive rendering images of the fetal stomach: a preliminary report.

    Science.gov (United States)

    Inubashiri, Eisuke; Abe, Kiyotaka; Watanabe, Yukio; Akutagawa, Noriyuki; Kuroki, Katumaru; Sugawara, Masaki; Maeda, Nobuhiko; Minami, Kunihiro; Nomura, Yasuhiro

    2015-01-01

    This study aimed to show reconstruction of the fetal stomach using the HDlive rendering mode in ultrasound. Seventeen healthy singleton fetuses at 18-34 weeks' gestational age were observed using the HDlive rendering mode of ultrasound in utero. In all of the fetuses, we identified specific spatial structures, including macroscopic anatomical features (e.g., the pyrous, cardia, fundus, and great curvature) of the fetal stomach, using the HDlive rendering mode. In particular, HDlive rendering images showed remarkably fine details that appeared as if they were being viewed under an endoscope, with visible rugal folds after 27 weeks' gestational age. Our study suggests that the HDlive rendering mode can be used as an additional method for evaluating the fetal stomach. The HDlive rendering mode shows detailed 3D structural images and anatomically realistic images of the fetal stomach. This technique may be effective in prenatal diagnosis for examining detailed information of fetal organs.

  1. The MathScheme Library: Some Preliminary Experiments

    CERN Document Server

    Carette, Jacques; Jeremic, Filip; Maccio, Vincent; O'Connor, Russell; Tran, Quang M

    2011-01-01

    We present some of the experiments we have performed to best test our design for a library for MathScheme, the mechanized mathematics software system we are building. We wish for our library design to use and reflect, as much as possible, the mathematical structure present in the objects which populate the library.

  2. Preliminary results of solar constant observations with the SOLCON experiment on ATLAS-1

    Science.gov (United States)

    Crommelynck, D.; Domingo, V.; Barkstrom, B.; Lee, R. B., II; Donaldson, J.; Telljohann, U; Warren, L.; Fichot, A.

    1994-01-01

    A brief description is given of the Solar Constant (SOLCAN) experiment on Atmospheric Laboratory for Applications and Science (ATLAS) 1, its scientific and technical objectives, as well as its measurement principle and its on board chronology of operations. A preliminary value of the solar constant during the third solar operation of the mission is also provided.

  3. THE MORPHOLOGICAL BASIS FOR OLFACTORY PERCEPTION OF STEROIDS DUING AGONISTIC BEHAVIOR IN LOBSTER: PRELIMINARY EXPERIMENTS

    Science.gov (United States)

    The morphological basis for olfactory perception of steroids during agonistic behavior in lobsters: preliminary experiments. Borsay Horowitz, DJ1, Kass-Simon, G2, Coglianese, D2, Martin, L2, Boseman, M2, Cromarty, S3, Randall, K3, Fini, A.3 1US EPA, NHEERL, ORD, Atlantic Ecology...

  4. CUTIE: Cubesat Ultraviolet Transient Imaging Experiment

    Science.gov (United States)

    Cenko, Stephen B.; Bellm, Eric Christopher; Gal-Yam, Avishay; Gezari, Suvi; Gorjian, Varoujan; Jewell, April; Kruk, Jeffrey W.; Kulkarni, Shrinivas R.; Mushotzky, Richard; Nikzad, Shouleh; Piro, Anthony; Waxman, Eli; Ofek, Eran Oded

    2017-01-01

    We describe a mission concept for the Cubesat Ultraviolet Transient Imaging Experiment (CUTIE). CUTIE will image an area on the sky of ~ 1700 square degrees every ~ 95 min at near-UV wavelengths (260-320 nm) to a depth of 19.0 mag (AB). These capabilities represent orders of magnitude improvement over past UV imagers, allowing CUTIE to conduct the first true synoptic survey of the transient and variable sky in the UV bandpass. CUTIE will uniquely address key Decadal Survey science questions such as how massive stars end their lives, how super-massive black holes accrete material and influence their surroundings, and how suitable habitable-zone planets around low-mass stars are for hosting life. By partnering with upcoming ground-based time-domain surveys, CUTIE will further leverage its low-Earth orbit to provide a multi-wavelength view of the dynamic universe that can only be achieved from space. The remarkable sensitivity for such a small payload is achieved via the use of large format delta-doped CCDs; space qualifying this technology will serve as a key milestone towards the development of future large missions (Explorers and Surveyors). Finally, our innovative design in a 6U cubesat form factor will enable significant cost savings, accelerating the timeline from conception to on-sky operation (5 years; well matched for graduate student participation).

  5. Preliminary experience with laparoscopic surgery in Ile-Ife, Nigeria.

    Science.gov (United States)

    Adisa, A O; Arowolo, O A; Salako, A A; Lawal, O O

    2009-12-01

    This study presents a pioneer experience with laparoscopic operations in a General Surgical unit of the Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria. Consecutive patients who had laparoscopic operations from April through December 2008 were prospectively studied. Following clinical diagnosis, initial diagnostic laparoscopy was undertaken in all patients, followed by therapeutic open or laparoscopic procedures. All procedures were done under general anaesthesia. Duration of operation and outcome including complications were recorded. In all, there were 12 patients (8 males, 4 females), aged 15 to 50 years. Eight patients had clinical diagnoses of acute appendicitis, one each had undetermined right lower abdominal pain suspected ectopic gestation, adhesive intestinal obstruction and metastatic liver disease. The first 4 patients with inflammed appendix confirmed at laparoscopy had open appendicectomy. Of the next cohort of 5 patients, laparoscopic appendicectomy was completed in four but converted to open procedure in one. Normal findings were noted in the lady with suspected ectopic gestation. Laparoscopic adhesiolysis was done for adhesive intestinal obstruction while a laparoscopic liver biopsy was done for the patient with metastatic liver disease. Operative time ranged from 55-105 minutes with marked reduction in operation time as confidence and experience grew. No intraoperative complication was observed but one patient had superficial port site infection postoperatively. We conclude that with good patient selection and some improvisation, laparoscopic general surgical operations are feasible with acceptable outcome even in a poor resource setting.

  6. Real-time elastography for detecting prostate cancer: preliminary experience.

    Science.gov (United States)

    Pallwein, Leo; Mitterberger, Michael; Struve, Peter; Pinggera, Germar; Horninger, Wolfgang; Bartsch, Georg; Aigner, Friedrich; Lorenz, Andreas; Pedross, Florian; Frauscher, Ferdinand

    2007-07-01

    To assess the use of real-time elastography (RTE) for detecting prostate cancer in patients scheduled for radical prostatectomy (RP), as most solid tumours differ in their consistency from the deriving tissue, and RTE might offer a new tool for cancer detection. We examined 15 patients (mean age 56 years, sd 6.2, range 46-71) with RTE, using an ultrasonography (US) system with a 7.5-MHz transrectal probe as a transducer. RTE is capable of visualizing displacements between pairs of US images of tissues when placed under axial compression. The stiffness of the lesion was displayed from blue (soft) to black (hard). Hard lesions with a diameter of > or = 5 mm were considered as malignant. All patients had the diagnosis of prostate cancer confirmed by biopsy and had a mean (range) prostate specific antigen (PSA) level of 4.6 (1.4-16.1) ng/mL; all were scheduled for RP. US was performed by two investigators and interpreted by consensus. Cancer location and size was determined in the RTE mode only. One pathologist classified tumour location, grade and stage. The RTE findings were compared with the pathological findings. There were no major complications during RP in any patient; all had a pT2 tumour on histopathological examination, the Gleason score was 5-9 and the mean (range) tumour size 1.1 (0.6-2.5) cm. Thirty-five foci of prostate cancer were present at the pathological evaluation; multiple foci were found in 11 of the 15 glands. RTE detected 28 of 35 cancer foci (sensitivity 80%). The per-patient analysis showed that RTE detected at least one cancer area in each of the 15 patients. Only four sites with false-positive findings on RTE and no histopathological correlation were detected; these findings were obtained in the first five patients (period of learning). RTE can be used to visualize differences in tissue elasticity. Our results show that RTE allows the detection of prostate cancer and estimation of tumour location and size. RTE of the prostate is a new

  7. Comparison of stroke infarction between CT perfusion and diffusion weighted imaging: preliminary results

    Science.gov (United States)

    Abd. Rahni, Ashrani Aizzuddin; Arka, Israna Hossain; Chellappan, Kalaivani; Mukari, Shahizon Azura; Law, Zhe Kang; Sahathevan, Ramesh

    2016-03-01

    In this paper we present preliminary results of comparison of automatic segmentations of the infarct core, between that obtained from CT perfusion (based on time to peak parameter) and diffusion weighted imaging (DWI). For each patient, the two imaging volumes were automatically co-registered to a common frame of reference based on an acquired CT angiography image. The accuracy of image registration is measured by the overlap of the segmented brain from both images (CT perfusion and DWI), measured within their common field of view. Due to the limitations of the study, DWI was acquired as a follow up scan up to a week after initial CT based imaging. However, we found significant overlap of the segmented brain (Jaccard indices of approximately 0.8) and the percentage of infarcted brain tissue from the two modalities were still fairly highly correlated (correlation coefficient of approximately 0.9). The results are promising with more data needed in future for clinical inference.

  8. Preliminary skyshine calculations for the Poloidal Diverter Tokamak Experiment

    Science.gov (United States)

    Nigg, D. W.; Wheeler, F. J.

    1981-01-01

    A calculational model is presented to estimate the radiation dose, due to the skyshine effect, in the control room and at the site boundary of the Poloidal Diverter Experiment (PDX) facility at Princeton University which requires substantial radiation shielding. The required composition and thickness of a water-filled roof shield that would reduce this effect to an acceptable level is computed, using an efficient one-dimensional model with an Sn calculation in slab geometry. The actual neutron skyshine dose is computed using a Monte Carlo model with the neutron source at the roof surface obtained from the slab Sn calculation, and the capture gamma dose is computed using a simple point-kernel single-scatter method. It is maintained that the slab model provides the exact probability of leakage out the top surface of the roof and that it is nearly as accurate as and much less costly than multi-dimensional techniques.

  9. A PRELIMINARY EXPERIMENT ON DENITRIFICATION OF WASTE LANDFILL LEACHATE

    Science.gov (United States)

    Wada, Nariaki; Nakamichi, Tamihiro; Yagi, Masahiro; Matsumoto, Toshihide; Kugimiya, Akikazu; Michioku, Kohji

    A laboratory experiment on denitrification was carried out in order to reduce nitrogen load from municipal landfill leachate. Nitrogen was efficiently removed by feeding sludge of the leachate pond into the tanks, which could activate denitrification bacteria. Although inorganic reducing agent such as iron powder was not able to make the whole water mass anoxic, denitrification took place by supplying organic matters such as methanol, hydrogen feeding agent, etc.. It is considered that small amount of anoxic water film produced on surfaces of container and carriers might contribute to denitrification, although the bulk water is kept aerobic. It is found that organic matters contained in the leachate is so insufficient that nitrification liquid circulation does not work well for denitrification.

  10. Preliminary Results of the Echo-Seeding Experiment ECHO-7 at SLAC

    Energy Technology Data Exchange (ETDEWEB)

    Xiang, D.; Colby, E.; Ding, Y.; Dunning, M.; Frederico, J.; Gilevich, S.; Hast, C.; Jobe, K.; McCormick, D.; Nelson, J.; Raubenheimer, T.O.; Soong, K.; Stupakov, G.; Szalata, Z.; Walz, D.; Weathersby, S.; Woodley, M.; /SLAC; Corlett, J.; Qiang, J.; Penn, G.; Prestemon, S.; /LBL, Berkeley /LPHE, Lausanne

    2010-06-15

    ECHO-7 is a proof-of-principle echo-enabled harmonic generation FEL experiment in the Next Linear Collider Test Accelerator (NLCTA) at SLAC. The experiment aims to generate coherent radiation at 318 nm and 227 nm, which are the 5th and 7th harmonic of the infrared seed laser. In this paper we present the preliminary results from the commissioning run of the completed experimental setup which started in April 2010.

  11. CT imaging of enhanced oil recovery experiments

    Energy Technology Data Exchange (ETDEWEB)

    Gall, B.L.

    1992-12-01

    X-ray computerized tomography (Cr) has been used to study fluid distributions during chemical enhanced oil recovery experiments. Four CT-monitored corefloods were conducted, and oil saturation distributions were calculated at various stages of the experiments. Results suggested that this technique could add significant information toward interpretation and evaluation of surfactant/polymer EOR recovery methods. CT-monitored tracer tests provided information about flow properties in the core samples. Nonuniform fluid advance could be observed, even in core that appeared uniform by visual inspection. Porosity distribution maps based on CT density calculations also showed the presence of different porosity layers that affected fluid movement through the cores. Several types of CT-monitored corefloods were conducted. Comparisons were made for CT-monitored corefloods using chemical systems that were highly successful in reducing residual oil saturations in laboratory experiments and less successful systems. Changes were made in surfactant formulation and in concentration of the mobility control polymer. Use of a poor mobility control agent failed to move oil that was not initially displaced by the injected surfactant solution; even when a good'' surfactant system was used. Use of a less favorable surfactant system with adequate mobility control could produce as much oil as the use of a good surfactant system with inadequate mobility control. The role of mobility control, therefore, becomes a critical parameter for successful application of chemical EOR. Continuation of efforts to use CT imaging in connection with chemical EOR evaluations is recommended.

  12. CT imaging of enhanced oil recovery experiments

    Energy Technology Data Exchange (ETDEWEB)

    Gall, B.L.

    1992-12-01

    X-ray computerized tomography (Cr) has been used to study fluid distributions during chemical enhanced oil recovery experiments. Four CT-monitored corefloods were conducted, and oil saturation distributions were calculated at various stages of the experiments. Results suggested that this technique could add significant information toward interpretation and evaluation of surfactant/polymer EOR recovery methods. CT-monitored tracer tests provided information about flow properties in the core samples. Nonuniform fluid advance could be observed, even in core that appeared uniform by visual inspection. Porosity distribution maps based on CT density calculations also showed the presence of different porosity layers that affected fluid movement through the cores. Several types of CT-monitored corefloods were conducted. Comparisons were made for CT-monitored corefloods using chemical systems that were highly successful in reducing residual oil saturations in laboratory experiments and less successful systems. Changes were made in surfactant formulation and in concentration of the mobility control polymer. Use of a poor mobility control agent failed to move oil that was not initially displaced by the injected surfactant solution; even when a ``good`` surfactant system was used. Use of a less favorable surfactant system with adequate mobility control could produce as much oil as the use of a good surfactant system with inadequate mobility control. The role of mobility control, therefore, becomes a critical parameter for successful application of chemical EOR. Continuation of efforts to use CT imaging in connection with chemical EOR evaluations is recommended.

  13. Preliminary experiments: High-energy alpha PIXE in archaeometry

    Energy Technology Data Exchange (ETDEWEB)

    Dupuis, Thomas, E-mail: T.Dupuis@ulg.ac.b [Centre Europeen d' Archeometrie, Atomique et Spectroscopie, Universite de Liege, Sart Tilman B15, B-4000 Liege (Belgium); Institut de Physique Nucleaire, Atomique et Spectroscopie, Universite de Liege, Sart Tilman B15, B-4000 Liege (Belgium); Chene, G.; Mathis, F. [Centre Europeen d' Archeometrie, Atomique et Spectroscopie, Universite de Liege, Sart Tilman B15, B-4000 Liege (Belgium); Institut de Physique Nucleaire, Atomique et Spectroscopie, Universite de Liege, Sart Tilman B15, B-4000 Liege (Belgium); Marchal, A.; Philippe, M.; Garnir, H.-P. [Institut de Physique Nucleaire, Atomique et Spectroscopie, Universite de Liege, Sart Tilman B15, B-4000 Liege (Belgium); Strivay, D. [Centre Europeen d' Archeometrie, Atomique et Spectroscopie, Universite de Liege, Sart Tilman B15, B-4000 Liege (Belgium); Institut de Physique Nucleaire, Atomique et Spectroscopie, Universite de Liege, Sart Tilman B15, B-4000 Liege (Belgium)

    2010-06-15

    This paper describes the work realized at the 'Centre Europeen d'Archeometrie' to highlight the utility of high-energy alpha PIXE in the particular field of archaeometry and to introduce the developments done and to be done to complete the knowledge of high-energy alpha PIXE. It starts with the comparison of the yield and the noise background between several alpha particle beams and the comparison between alpha particle and proton beams on different thick and thin references. After, this paper depicts the developments done at the 'Institut de Physique Nucleaire, Atomique et Spectroscopie' to perform such high-energy experiments, first on standards and later on cultural heritage objects. Moreover, it introduces the problematics of such beams for the quantification in PIXE by the intermediary of the knowledge of the ionization and X-ray production cross-sections and also the developments done to answer to this serious lack in the databases.

  14. Mitchell′s technique for epispadias repair: Our preliminary experience

    Directory of Open Access Journals (Sweden)

    Sarin Yogesh

    2006-01-01

    Full Text Available Aim: We present here experience of a single surgeon with Mitchell′s procedure for correction of epispadias. Materials and Methods: Nine boys (mean age 5½ years, range 9 months to 16 years underwent Mitchell′s repair in Department of Pediatric Surgery over a period of 5½ (September 1999 to March 2005 for correction of epispadias. Six of these patients had come for the second stage of exstrophy-epispadias repair after primary bladder closure; the other three had incontinent penopubic epispadias. Results: The penis was cosmetically acceptable as regards to size, glans shape and peno-pubic angle in all the patients. However, there was a high incidence of penopubic fistula (44%. These patients with penopubic fistula also required postoperative urethral dilatations, at times repeated. One of the common factors to these subset patients was their younger age when Mitchell′s urethroplasty was performed. Limitations: The series is descriptive in nature, short in numbers and does not provide statistical comparison of Mitchell′s procedure with the previously done procedures. Conclusions: Mitchell′s complete penile disassembly technique for epispadias repair is more acceptable anatomical procedure that results in near-pendulous penis. However, when performed at young age, it is fraught with the complication of penopubic fistula similar to that as seen with Cantwell-Ransley′s procedure. Mitchell′s procedure creates a hypospadiac meatus initially and the meatal advancement is required as for any other distal penile/coronal hypospadias.

  15. Preliminary experience with biodegradable implants for fracture fixation

    Directory of Open Access Journals (Sweden)

    Dhillon Mandeep

    2008-01-01

    Full Text Available Background: Biodegradable implants were designed to overcome the disadvantages of metal-based internal fixation devices. Although they have been in use for four decades internationally, many surgeons in India continue to be skeptical about the mechanical strength of biodegradable implants, hence this study. Materials and Methods: A prospective study was done to assess the feasibility and surgeon confidence level with biodegradable implants over a 12-month period in an Indian hospital. Fifteen fractures (intra-articular, metaphyseal or small bone fractures were fixed with biodegradable implants. The surgeries were randomly scheduled so that different surgeons with different levels of experience could use the implants for fixation. Results: Three fractures (one humeral condyle, two capitulum, were supplemented by additional K-wires fixation. Trans-articular fixator was applied in two distal radius and two pilon fractures where bio-pins alone were used. All fractures united, but in two cases the fracture displaced partially during the healing phase; one fibula due to early walking, and one radius was deemed unstable even after bio-pin and external fixator. Conclusions: Biodegradable -implants are excellent for carefully selected cases of intra-articular fractures and some small bone fractures. However, limitations for use in long bone fractures persist and no great advantage is gained if a "hybrid" composite is employed. The mechanical properties of biopins and screws in isolation are perceived to be inferior to those of conventional metal implants, leading to low confidence levels regarding the stability of reduced fractures; these implants should be used predominantly in fracture patterns in which internal fixation is subjected to minimal stress.

  16. Preliminary Experience with a New Total Distal Radioulnar Joint Replacement

    Science.gov (United States)

    Ewald, Timothy J.; Skeete, Kshamata; Moran, Steven L.

    2012-01-01

    resurfacing design may provide a means of decreasing pain and restoring DRUJ stability and motion following severe trauma, failed hemiarthroplasty, or failed Sauvé–Kapandji procedure. More experience is needed with this implant to confirm these initial encouraging results. The level of evidence for this study is IV (therapeutic, case series). PMID:23904976

  17. Preliminary examples of 3D vector flow imaging

    DEFF Research Database (Denmark)

    Pihl, Michael Johannes; Stuart, Matthias Bo; Tomov, Borislav Gueorguiev

    2013-01-01

    and visualized using three alternative approaches. Practically no in-plane motion (vx and vz) is measured, whereas the out-of-plane motion (vy) and the velocity magnitude exhibit the expected 2D circular-symmetric parabolic shape. It shown that the ultrasound method is suitable for real-time data acquisition...... ultrasound scanner SARUS on a flow rig system with steady flow. The vessel of the flow-rig is centered at a depth of 30 mm, and the flow has an expected 2D circular-symmetric parabolic prole with a peak velocity of 1 m/s. Ten frames of 3D vector flow images are acquired in a cross-sectional plane orthogonal...... to the center axis of the vessel, which coincides with the y-axis and the flow direction. Hence, only out-of-plane motion is expected. This motion cannot be measured by typical commercial scanners employing 1D arrays. Each frame consists of 16 flow lines steered from -15 to 15 degrees in steps of 2 degrees...

  18. DYNAMIC MAGNETIC RESONANCE IMAGING: PRELIMINARY PRESENTATION OF A TECHNIQUE

    Directory of Open Access Journals (Sweden)

    BRUNO DA COSTA ANCHESCHI

    Full Text Available ABSTRACT Objective: To evaluate morphometric variations of the cervical spine in patients with cervical spondylotic myelopathy (CSM using dynamic magnetic resonance imaging (MRI in neutral, flexion and extension positions. Methods: This is a prospective study of patients with CSM secondary to degenerative disease of the cervical spine. The morphometric parameters were evaluated using T2-weighted MRI sequences in the sagittal plane in neutral, flexion and extension position of the neck. The parameters studied were the anterior length of the spinal cord (ALSC, the posterior length of the spinal cord (PLSC, the diameter of the vertebral canal (DVC and the diameter of the spinal cord (DSC. Results: The ALSC and PLSC were longer in flexion than in extension and neutral position, with statistically significant difference between the flexion and extension position. The DVC and the DSC were greater in flexion than in extension and neutral position, however, there was no statistically significant difference when they were compared in the neutral, flexion and extension positions. Conclusion: Dynamic MRI allows to evaluate morphometric variations in the cervical spinal canal in patients with cervical spondylotic myelopathy.

  19. The ESO Imaging Survey Status Report and Preliminary Results

    CERN Document Server

    Da Costa, L N; Deul, E; Erben, T; Freudling, W; Guarnieri, M D; Hook, I; Hook, R N; Méndez, R; Nonino, M; Olsen, L; Prandoni, I; Renzini, A; Savaglio, S; Scodeggio, M; Silva, D; Slijkhuis, R; Wicenec, A; Wichmann, R; Benoist, C

    1998-01-01

    The ESO Imaging Survey (EIS) presented in early issues of the Messenger, and with up-to-date information on the ongoing observations available on the Web (http://www.eso.org/eis), is a concerted effort by ESO and the Member State community to provide targets for the first year of operation of the VLT. It consists of two parts: a relatively wide-angle survey (EIS-WIDE) to cover four pre-selected patches of sky, 6 square degrees each, spread in right ascension to search for distant clusters and quasars and a deep, multicolor survey of four optical (SUSI-2) and two infrared (SOFI) covering the HST/Hubble Deep Field South (HDFS) and its flanking fields (EIS-DEEP). From the start, the main challenge has been to carry out a public survey in a limited amount of time requiring observations, software development and data reduction with the goal of distributing the survey data products before the call for proposal for the VLT. To cope with this one-year timetable, a novel type of collaboration between ESO and the commu...

  20. Fusion Core Imaging Experiment Based on the Shenguang Ⅱ Facility

    Institute of Scientific and Technical Information of China (English)

    郑志坚; 曹磊峰; 滕浩; 成金秀

    2002-01-01

    A laser fusion experiment was performed based on the Shenguang Ⅱ facility. An image of thermonuclear burning region was obtained with a Fresnel zone plate-coded imaging technique, where the laser-driven target was served as an α-particle source, and the coded image obtained in the experiment was reconstructed by a numerical way.

  1. Muon-catalyzed fusion experiment target and detector system. Preliminary design report

    Energy Technology Data Exchange (ETDEWEB)

    Jones, S.E.; Watts, K.D.; Caffrey, A.J.; Walter, J.B.

    1982-03-01

    We present detailed plans for the target and particle detector systems for the muon-catalyzed fusion experiment. Requirements imposed on the target vessel by experimental conditions and safety considerations are delineated. Preliminary designs for the target vessel capsule and secondary containment vessel have been developed which meet these requirements. In addition, the particle detection system is outlined, including associated fast electronics and on-line data acquisition. Computer programs developed to study the target and detector system designs are described.

  2. Charge generation associated with liquid spraying in tank cleaning and comparable processes - preliminary experiments

    Science.gov (United States)

    Blum, Carsten; Losert, Oswald F. J.

    2015-10-01

    The BG RCI has initiated investigations in order to improve the data basis for assessing the ignition hazard by electrostatic charging processes associated with the spraying of liquids. On the base of preliminary experiments, we established procedures for measurements of electric field strength and charging current in the presence of aerosol particles. Results obtained with three different nozzle types, variation of pressure and with built-in deflecting plate are presented.

  3. The RPC-based IFR system at BaBar experiment preliminary results

    CERN Document Server

    Piccolo, D; Bagnasco, S; Baldini, R; Band, H R; Bionta, R; Buzzo, A; Calcaterra, A; Cavallo, N; Contri, R; Crosetti, G; De Nardo, Gallieno; De Sangro, R; Fabozzi, F; Falciai, D; Finocchiaro, G; Gatto, C; Johnson, J; Lista, L; Lo Vetere, M; Macri, M; Monge, R; Palano, A; Paolucci, P; Passaggio, S; Patrignani, C; Patteri, P; Peruzzi, I; Piccolo, M; Robutti, E; Santroni, A; Sciacca, C; Wright, D; Yu, Z; Zallo, A

    2002-01-01

    The IFR system is a RPC-based detector used to identify muons and neutral hadrons in the BaBar experiment at PEP II machine in SLAC. The RPC system can be used to reconstruct the trajectory of muons, pions and neutral hadrons interacting in the iron of the IFR. The different range and hit pattern allow to discriminate different particles crossing the IFR. An overview of the system design and the preliminary results on the IFR performances are reported.

  4. THE Q/U IMAGING EXPERIMENT INSTRUMENT

    Energy Technology Data Exchange (ETDEWEB)

    Bischoff, C.; Brizius, A.; Buder, I.; Kusaka, A.; Smith, K. M.; Bogdan, M. [Kavli Institute for Cosmological Physics, Department of Physics, Enrico Fermi Institute, The University of Chicago, Chicago, IL 60637 (United States); Chinone, Y. [High Energy Accelerator Research Organization (KEK), 1-1 Oho, Tsukuba, Ibaraki 305-0801 (Japan); Cleary, K.; Reeves, R. [Cahill Center for Astronomy and Astrophysics, California Institute of Technology, 1200 E. California Blvd M/C 249-17, Pasadena, CA 91125 (United States); Dumoulin, R. N.; Newburgh, L. B. [Department of Physics and Columbia Astrophysics Laboratory, Columbia University, New York, NY 10027 (United States); Monsalve, R.; Bustos, R. [Department of Physics, University of Miami, 1320 Campo Sano Drive, Coral Gables, FL 33146 (United States); Naess, S. K. [Institute of Theoretical Astrophysics, University of Oslo, P.O. Box 1029 Blindern, N-0315 Oslo (Norway); Nixon, G. [Joseph Henry Laboratories of Physics, Jadwin Hall, Princeton University, Princeton, NJ 08544 (United States); Vanderlinde, K. [Department of Physics, McGill University, 3600 Rue University, Montreal, Quebec H3A 2T8 (Canada); Wehus, I. K. [Department of Physics, University of Oslo, P.O. Box 1048 Blindern, N-0316 Oslo (Norway); Church, S. E. [Kavli Institute for Particle Astrophysics and Cosmology and Department of Physics, Stanford University, Varian Physics Building, 382 Via Pueblo Mall, Stanford, CA 94305 (United States); Davis, R.; Dickinson, C., E-mail: newburgh@princeton.edu [Jodrell Bank Centre for Astrophysics, Alan Turing Building, School of Physics and Astronomy, University of Manchester, Oxford Road, Manchester M13 9PL (United Kingdom); and others

    2013-05-01

    The Q/U Imaging ExperimenT (QUIET) is designed to measure polarization in the cosmic microwave background, targeting the imprint of inflationary gravitational waves at large angular scales({approx}1 Degree-Sign ). Between 2008 October and 2010 December, two independent receiver arrays were deployed sequentially on a 1.4 m side-fed Dragonian telescope. The polarimeters that form the focal planes use a compact design based on high electron mobility transistors (HEMTs) that provides simultaneous measurements of the Stokes parameters Q, U, and I in a single module. The 17-element Q-band polarimeter array, with a central frequency of 43.1 GHz, has the best sensitivity (69 {mu}Ks{sup 1/2}) and the lowest instrumental systematic errors ever achieved in this band, contributing to the tensor-to-scalar ratio at r < 0.1. The 84-element W-band polarimeter array has a sensitivity of 87 {mu}Ks{sup 1/2} at a central frequency of 94.5 GHz. It has the lowest systematic errors to date, contributing at r < 0.01. The two arrays together cover multipoles in the range l {approx} 25-975. These are the largest HEMT-based arrays deployed to date. This article describes the design, calibration, performance, and sources of systematic error of the instrument.

  5. Fiscal year 1981 US corn and soybeans pilot preliminary experiment plan, phase 1

    Science.gov (United States)

    Livingston, G. P.; Nedelman, K. S.; Norwood, D. F.; Smith, J. H. (Principal Investigator)

    1981-01-01

    A draft of the preliminary experiment plan for the foreign commodity production forecasting project fiscal year 1981 is presented. This draft plan includes: definition of the phase 1 and 2 U.S. pilot objectives; the proposed experiment design to evaluate crop calendar, area estimation, and area aggregation components for corn and soybean technologies using 1978/1979 crop-year data; a description of individual sensitivity evaluations of the baseline corn and soybean segment classification procedure; and technology and data assessment in support of the corn and soybean estimation technology for use in the U.S. central corn belt.

  6. Preliminary Image Map of the 2007 Buckweed Fire Perimeter, Agua Dulce Quadrangle, Los Angeles County, California

    Science.gov (United States)

    Clark, Perry S.; Scratch, Wendy S.; Bias, Gaylord W.; Stander, Gregory B.; Sexton, Jenne L.; Krawczak, Bridgette J.

    2008-01-01

    In the fall of 2007, wildfires burned out of control in southern California. The extent of these fires encompassed large geographic areas that included a variety of landscapes from urban to wilderness. The U.S. Geological Survey National Geospatial Technical Operations Center (NGTOC) is currently (2008) developing a quadrangle-based 1:24,000-scale image map product. One of the concepts behind the image map product is to provide an updated map in electronic format to assist with emergency response. This image map is one of 55 preliminary image map quadrangles covering the areas burned by the southern California wildfires. Each map is a layered, geo-registered Portable Document Format (.pdf) file. For more information about the layered geo-registered .pdf, see the readme file (http://pubs.usgs.gov/of/2008/1029/downloads/CA_Agua_Dulce_of2008-1029_README.txt). To view the areas affected and the quadrangles mapped in this preliminary project, see the map index (http://pubs.usgs.gov/of/2008/1029/downloads/CA_of2008_1029-1083_index.pdf) provided with this report.

  7. Preliminary Image Map of the 2007 Harris Fire Perimeter, Morena Reservoir Quadrangle, San Diego County, California

    Science.gov (United States)

    Clark, Perry S.; Scratch, Wendy S.; Bias, Gaylord W.; Stander, Gregory B.; Sexton, Jenne L.; Krawczak, Bridgette J.

    2008-01-01

    In the fall of 2007, wildfires burned out of control in southern California. The extent of these fires encompassed large geographic areas that included a variety of landscapes from urban to wilderness. The U.S. Geological Survey National Geospatial Technical Operations Center (NGTOC) is currently (2008) developing a quadrangle-based 1:24,000-scale image map product. One of the concepts behind the image map product is to provide an updated map in electronic format to assist with emergency response. This image map is one of 55 preliminary image map quadrangles covering the areas burned by the southern California wildfires. Each map is a layered, geo-registered Portable Document Format (.pdf) file. For more information about the layered geo-registered .pdf, see the readme file (http://pubs.usgs.gov/of/2008/1029/downloads/CA_Agua_Dulce_of2008-1029_README.txt). To view the areas affected and the quadrangles mapped in this preliminary project, see the map index (http://pubs.usgs.gov/of/2008/1029/downloads/CA_of2008_1029-1083_index.pdf) provided with this report.

  8. Preliminary Image Map of the 2007 Slide Fire Perimeter, Harrison Mountain Quadrangle, San Bernardino County, California

    Science.gov (United States)

    Clark, Perry S.; Scratch, Wendy S.; Bias, Gaylord W.; Stander, Gregory B.; Sexton, Jenne L.; Krawczak, Bridgette J.

    2008-01-01

    In the fall of 2007, wildfires burned out of control in southern California. The extent of these fires encompassed large geographic areas that included a variety of landscapes from urban to wilderness. The U.S. Geological Survey National Geospatial Technical Operations Center (NGTOC) is currently (2008) developing a quadrangle-based 1:24,000-scale image map product. One of the concepts behind the image map product is to provide an updated map in electronic format to assist with emergency response. This image map is one of 55 preliminary image map quadrangles covering the areas burned by the southern California wildfires. Each map is a layered, geo-registered Portable Document Format (.pdf) file. For more information about the layered geo-registered .pdf, see the readme file (http://pubs.usgs.gov/of/2008/1029/downloads/CA_Agua_Dulce_of2008-1029_README.txt). To view the areas affected and the quadrangles mapped in this preliminary project, see the map index (http://pubs.usgs.gov/of/2008/1029/downloads/CA_of2008_1029-1083_index.pdf) provided with this report.

  9. Preliminary Image Map of the 2007 Witch Fire Perimeter, Santa Ysabel Quadrangle, San Diego County, California

    Science.gov (United States)

    Clark, Perry S.; Scratch, Wendy S.; Bias, Gaylord W.; Stander, Gregory B.; Sexton, Jenne L.; Krawczak, Bridgette J.

    2008-01-01

    In the fall of 2007, wildfires burned out of control in southern California. The extent of these fires encompassed large geographic areas that included a variety of landscapes from urban to wilderness. The U.S. Geological Survey National Geospatial Technical Operations Center (NGTOC) is currently (2008) developing a quadrangle-based 1:24,000-scale image map product. One of the concepts behind the image map product is to provide an updated map in electronic format to assist with emergency response. This image map is one of 55 preliminary image map quadrangles covering the areas burned by the southern California wildfires. Each map is a layered, geo-registered Portable Document Format (.pdf) file. For more information about the layered geo-registered .pdf, see the readme file (http://pubs.usgs.gov/of/2008/1029/downloads/CA_Agua_Dulce_of2008-1029_README.txt). To view the areas affected and the quadrangles mapped in this preliminary project, see the map index (http://pubs.usgs.gov/of/2008/1029/downloads/CA_of2008_1029-1083_index.pdf) provided with this report.

  10. Preliminary Image Map of the 2007 Witch Fire Perimeter, Warners Ranch Quadrangle, San Diego County, California

    Science.gov (United States)

    Clark, Perry S.; Scratch, Wendy S.; Bias, Gaylord W.; Stander, Gregory B.; Sexton, Jenne L.; Krawczak, Bridgette J.

    2008-01-01

    In the fall of 2007, wildfires burned out of control in southern California. The extent of these fires encompassed large geographic areas that included a variety of landscapes from urban to wilderness. The U.S. Geological Survey National Geospatial Technical Operations Center (NGTOC) is currently (2008) developing a quadrangle-based 1:24,000-scale image map product. One of the concepts behind the image map product is to provide an updated map in electronic format to assist with emergency response. This image map is one of 55 preliminary image map quadrangles covering the areas burned by the southern California wildfires. Each map is a layered, geo-registered Portable Document Format (.pdf) file. For more information about the layered geo-registered .pdf, see the readme file (http://pubs.usgs.gov/of/2008/1029/downloads/CA_Agua_Dulce_of2008-1029_README.txt). To view the areas affected and the quadrangles mapped in this preliminary project, see the map index (http://pubs.usgs.gov/of/2008/1029/downloads/CA_of2008_1029-1083_index.pdf) provided with this report.

  11. Quantitative measure in image segmentation for skin lesion images: A preliminary study

    Science.gov (United States)

    Azmi, Nurulhuda Firdaus Mohd; Ibrahim, Mohd Hakimi Aiman; Keng, Lau Hui; Ibrahim, Nuzulha Khilwani; Sarkan, Haslina Md

    2014-12-01

    Automatic Skin Lesion Diagnosis (ASLD) allows skin lesion diagnosis by using a computer or mobile devices. The idea of using a computer to assist in diagnosis of skin lesions was first proposed in the literature around 1985. Images of skin lesions are analyzed by the computer to capture certain features thought to be characteristic of skin diseases. These features (expressed as numeric values) are then used to classify the image and report a diagnosis. Image segmentation is often a critical step in image analysis and it may use statistical classification, thresholding, edge detection, region detection, or any combination of these techniques. Nevertheless, image segmentation of skin lesion images is yet limited to superficial evaluations which merely display images of the segmentation results and appeal to the reader's intuition for evaluation. There is a consistent lack of quantitative measure, thus, it is difficult to know which segmentation present useful results and in which situations they do so. If segmentation is done well, then, all other stages in image analysis are made simpler. If significant features (that are crucial for diagnosis) are not extracted from images, it will affect the accuracy of the automated diagnosis. This paper explore the existing quantitative measure in image segmentation ranging in the application of pattern recognition for example hand writing, plat number, and colour. Selecting the most suitable segmentation measure is highly important so that as much relevant features can be identified and extracted.

  12. The NASA Juncture Flow Experiment: Goals, Progress, and Preliminary Testing (Invited)

    Science.gov (United States)

    Rumsey, Christopher L.; Neuhart, Danny H.; Kegerise, Michael A.

    2016-01-01

    NASA has been working toward designing and conducting a juncture flow experiment on a wing-body aircraft configuration. The experiment is planned to provide validation-quality data for CFD that focuses on the onset and progression of a separation bubble near the wing-body juncture trailing edge region. This paper describes the goals and purpose of the experiment. Although currently considered unreliable, preliminary CFD analyses of several different configurations are shown. These configurations have been subsequently tested in a series of "risk-reduction" wind tunnel tests, in order to help down-select to a final configuration that will attain the desired flow behavior. The risk-reduction testing at the higher Reynolds number has not yet been completed (at the time of this writing), but some results from one of the low-Reynolds-number experiments are shown.

  13. Experiences with digital processing of images at INPE

    Science.gov (United States)

    Mascarenhas, N. D. A. (Principal Investigator)

    1984-01-01

    Four different research experiments with digital image processing at INPE will be described: (1) edge detection by hypothesis testing; (2) image interpolation by finite impulse response filters; (3) spatial feature extraction methods in multispectral classification; and (4) translational image registration by sequential tests of hypotheses.

  14. An evaluation of the Positive Emotional Experiences Scale: A preliminary analysis

    Directory of Open Access Journals (Sweden)

    Rene van Wyk

    2016-04-01

    Full Text Available Orientation: The positive organisational behaviour movement emphasises the advantages of psychological strengths in business. The psychological virtues of positive emotional experiences can potentially promote human strengths to the advantages of business functioning and the management of work conditions. This is supported by Fredrickson’s broaden-and-build theory that emphasises the broadening of reactive thought patterns through experiences of positive emotions.Research purpose: A preliminary psychometric evaluation of a positive measurement of dimensions of emotional experiences in the workplace, by rephrasing the Kiefer and Barclay Toxic Emotional Experiences Scale.Motivation for the study: This quantitative Exploratory Factor Analysis investigates the factorial structure and reliability of the Positive Emotional Experiences Scale, a positive rephrased version of the Toxic Emotional Experiences Scale.Research approach, design and method: This Exploratory Factor Analysis indicates an acceptable three-factor model for the Positive Emotional Experiences Scale. These three factors are: (1 psychological recurrent positive state, (2 social connectedness and (3 physical refreshed energy, with strong Cronbach’s alphas of 0.91, 0.91 and 0.94, respectively.Main findings: The three-factor model of the Positive Emotional Experiences Scale provides a valid measure in support of Fredrickson’s theory of social, physical and psychological endured personal resources that build positive emotions.Practical/Managerial implications: Knowledge gained on positive versus negative emotional experiences could be applied by management to promote endured personal resources that strengthen positive emotional experiences.Contribution/value-add: The contribution of this rephrased Positive Emotional Experiences Scale provides a reliable measure of assessment of the social, physical and endured psychological and personal resources identified in Fredrickson’s broaden

  15. ISPA (imaging silicon pixel array) experiment

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    Application components of ISPA tubes are shown: the CERN-developed anode chip, special windows for gamma and x-ray detection, scintillating crystal and fibre arrays for imaging and tracking of ionizing particles.

  16. BIOMEX (Biology and Mars Experiment): Preliminary results on Antarctic black cryptoendolithic fungi in ground based experiments

    OpenAIRE

    C. Pacelli; Selbmann, L.; S. Onofri; de Vera, J.P.P.

    2014-01-01

    The main goal for astrobiologists is to find traces of present or past life in extraterrestrial environment or in meteorites. Biomolecules, such as lipids, pigments or polysaccharides, may be useful to establish the presence of extant or extinct life (Simoneit, B et al., 1998). BIOMEX (Biology and Mars Experiment) aims to measure to what extent biomolecules, such as pigments and cellular components, preserve their stability under space and Mars-like conditions. The experiment has just been la...

  17. Spinel dissolution via addition of glass forming chemicals. Results of preliminary experiments

    Energy Technology Data Exchange (ETDEWEB)

    Fox, K. M. [Savannah River Site (SRS), Aiken, SC (United States); Johnson, F. C. [Savannah River Site (SRS), Aiken, SC (United States)

    2015-11-01

    Increased loading of high level waste in glass can lead to crystallization within the glass. Some crystalline species, such as spinel, have no practical impact on the chemical durability of the glass, and therefore may be acceptable from both a processing and a product performance standpoint. In order to operate a melter with a controlled amount of crystallization, options must be developed for remediating an unacceptable accumulation of crystals. This report describes preliminary experiments designed to evaluate the ability to dissolve spinel crystals in simulated waste glass melts via the addition of glass forming chemicals (GFCs).

  18. Preliminary experience with Piccolo Composite™, a radiolucent distal fibula plate, in ankle fractures.

    Science.gov (United States)

    Caforio, Marco; Perugia, Dario; Colombo, Massimiliano; Calori, Giorgio Maria; Maniscalco, Pietro

    2014-12-01

    The radiolucent plate has many advantageous properties in the treatment of complex ankle fractures, particularly trimalleolar fractures. Surgeons may sometimes have difficulty observing the posterior malleolus after synthesis of lateral malleolus with a traditional plate because common materials of conventional plates are not radiolucent. In this study, the authors highlight the importance of the radiolucent property in the treatment of ankle fractures and describe their preliminary experience with a carbon fibre-reinforced polyetheretherketone distal fibula plate, with good results at 4 months' follow-up and no signs of tissue inflammatory reaction.

  19. Percutaneous pulmonary valve implantation in a single artery branch: A preliminary experience

    Institute of Scientific and Technical Information of China (English)

    Massimo; Chessa; Gianfranco; Butera; Luca; Giugno; Angelo; Micheletti; Diana; G; Negura; Mario; Carminati

    2015-01-01

    To describe preliminary experience of percutaneous pulmonary valve implantation, in a single pulmonary branch position. Two procedures in 2 patients from a single center are described, where implantation of percutaneous valves within a single pulmonary artery branch was technically successful. The procedural indication was pulmonary valve regurgitation and/or residual stenosis. The 2 patients were symptomatic. An Edwards Sapien? valve(Patient 1), and a Medtronic Melody? valve(Patient 2) were implanted. Both pts were discharged with an excellent valve function. In this report it is underlined that this modality is technically feasible and may be considered an option in patients with congenital heart defect under special circumstances.

  20. Low-dose fetal CT for evaluation of severe congenital skeletal anomalies: preliminary experience

    Energy Technology Data Exchange (ETDEWEB)

    Victoria, Teresa; Epelman, Monica; Johnson, Ann M.; Kramer, Sandra; Jaramillo, Diego [Children' s Hospital of Philadelphia, Diagnostic Imaging, Philadelphia, PA (United States); Bebbington, Michael [Children' s Hospital of Philadelphia, Center for Fetal Diagnosis and Treatment, Philadelphia, PA (United States); Wilson, R.D. [University of Calgary, Obstetrics and Gynecology, Calgary (Canada)

    2012-01-15

    Congenital skeletal abnormalities compose a heterogeneous and complex group of conditions that affect bone growth and development and result in various anomalies in shape and size of the skeleton. Prenatal sonographic diagnosis of these anomalies is challenging because of the relative rarity of each skeletal dysplasia, the multitude of differential diagnoses encountered when the bony abnormalities are identified, lack of precise molecular diagnosis and the fact that many of these disorders have overlapping features and marked phenotypic variability. The following review is a preliminary summary of our experience at the Children's Hospital of Philadelphia (CHOP) using low-dose fetal CT in the evaluation of severe fetal osseous abnormalities. (orig.)

  1. 小粒径磁共振成像超敏感纳米对比剂的研制及初步动物实验%Preparation and preliminary animal experiment of a small size and super-sensitive magnetic resonance imaging nano-contrast agent

    Institute of Scientific and Technical Information of China (English)

    洪国斌; 周经兴; 苑仁旭; 李新春

    2011-01-01

    目的 制备一种小粒径磁共振成像(MRI)超敏感的纳米对比剂并进行初步动物实验,探讨其用于分子影像学研究的可行性.方法 利用聚乙二醇(PEG)引发ε-己内酯(CL)开环聚合与自组装技术制备嵌段聚合物PEG-b-PCL,在其疏水性内核负载单颗粒超顺磁性氧化铁(SPIO)制成纳米对比剂.应用透射电子显微镜测量该纳米对比剂的粒径,原子吸收法测量其SPIO负载率,多平面回波SE序列测量T2值并计算横向弛豫率R2,同时对其进行磁学性质测量.将纳米对比剂由鼠尾静脉注射入Balb/c裸鼠体内,利用MRI于注射前、注射后1、3、6、12、24 h共6个时间点进行扫描,观察其在裸鼠体内的分布特点及循环时间.结果 制备的纳米对比剂粒径为(38±3)am,Fe3O4含量为37.0%,横向弛豫率R2为110 Fe(mmol/L)-1·s-1;磁学性质测定结果表明其具有超顺磁性.经外周静脉注射后,主要分布于肝脏,且循环时间长,与注射前相比,1 h信号强度明显降低(498±60比120±32,P<0.05),至24 h降低至88+28(P<0.05).结论 负载单颗粒SPIO的聚合物纳米对比剂粒径小、MRI超敏感,具有成为MRI对比剂并用于分子靶向成像的潜能.%Objective To synthesize a small size and super-sensitive magnetic resonance imaging (MRI) nano-contrast agent for preliminary animal experiment and to explore the feasibility for its use in molecular imaging studies.Methods Polyethylene glycol (PEC) was used for ring-opening polymerization of ε-caprolactone(CL), and amphiphilic PEG-b-PCL block polymer was prepared by self-assembly technique.Single particle superparamagnetic iron oxide (SPIO) was loaded at the hydrophobic core of PEG-b-PCL to develop a nano-contrast agent.The particle diameter and SPIO-loading density were respectively determined by transmission electron microscope and atomic absorption spectroscopy.Echo multiplanar sequence was used for T2 value test, with transverse relaxation rate R2 computed

  2. X-ray phase computed tomography for nanoparticulated imaging probes and therapeutics: preliminary feasibility study

    Science.gov (United States)

    Tang, Xiangyang; Yang, Yi; Tang, Shaojie

    2011-03-01

    With the scientific progress in cancer biology, pharmacology and biomedical engineering, the nano-biotechnology based imaging probes and therapeutical agents (namely probes/agents) - a form of theranostics - are among the strategic solutions bearing the hope for the cure of cancer. The key feature distinguishing the nanoparticulated probes/agents from their conventional counterparts is their targeting capability. A large surface-to-volume ratio in nanoparticulated probes/agents enables the accommodation of multiple targeting, imaging and therapeutic components to cope with the intra- and inter-tumor heterogeneity. Most nanoparticulated probes/agents are synthesized with low atomic number materials and thus their x-ray attenuation are very similar to biological tissues. However, their microscopic structures are very different, which may result in significant differences in their refractive properties. Recently, the investigation in the x-ray grating-based differential phase contrast (DPC) CT has demonstrated its advantages in differentiating low-atomic materials over the conventional attenuation-based CT. We believe that a synergy of x-ray grating-based DPC CT and nanoparticulated imaging probes and therapeutic agents may play a significant role in extensive preclinical and clinical applications, or even become a modality for molecular imaging. Hence, we propose to image the refractive property of nanoparticulated imaging probes and therapeutical agents using x-ray grating-based DPC CT. In this work, we conduct a preliminary feasibility study with a focus to characterize the contrast-to-noise ratio (CNR) and contrast-detail behavior of the x-ray grating-based DPC CT. The obtained data may be instructive to the architecture design and performance optimization of the x-ray grating-based DPC CT for imaging biomarker-targeted imaging probes and therapeutic agents, and even informative to the translation of preclinical research in theranostics into clinical applications.

  3. A Preliminary Study of Automatic Delineation of Eyes on CT Images Using Ant Colony Optimization

    Institute of Scientific and Technical Information of China (English)

    LI Yong-jie; XIE Wei-fu; YAO De-zhong

    2007-01-01

    Eyes are important organs-at-risk (OARs) that should be protected during the radiation treatment of those head tumors. Correct delineation of the eyes on CT images is one of important issues for treatment planning to protect the eyes as much as possible. In this paper, we propose a new method, named ant colony optimization (ACO), to delineate the eyes automatically.In the proposed algorithm, each ant tries to find a closed path, and some pheromone is deposited on the visited path when the ant finds a path. After all ants finish a circle, the best ant will lay some pheromone to enforce the best path. The proposed algorithm is verified on several CT images, and the preliminary results demonstrate the feasibility of ACO for the delineation problem.

  4. ISPA (imaging silicon pixel array) experiment

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    On the table, under the scrutiny of some collaboration members, an ISPA tube (upper-left of the table) with some of its application components is shown: they consist of the CERN-developed anode chip, special windows for gamma and x-ray detection, scintillating crystal and fibre arrays for imaging and tracking of ionizing particles.

  5. China ADS sub-critical experimental assembly-Venus-1 and preliminary experiment

    Institute of Scientific and Technical Information of China (English)

    SHI Yongqian; ZHANG Wei; CAO Jian; QUAN Yanhui; LUO Huangda; WU Xiaofei; XIA Pu; LUO Zhanglin; ZHAO Zhixiang; DING Dazhao; LI Yiguo; ZHU Qinfu; XIA Haihong; LI Jien

    2007-01-01

    China's accelerator-driven sub-critical system (ADS) sub-critical experimental assembly--Venus-1 and the preliminary experiment is presented. The core of Venus-1 is a coupled one of a fast neutron zone and a thermal neutron zone. The fast neutron zone is at the centre of the core and formed by natural uranium fuel. A fast neutron spectrum field can be produced in the fast neutron zone and used for the transmutation of minor actinides (Mas). The thermal neutron zone surrounds the fast neutron zone and is formed by low-enriched uranium fuel. It is a fission zone. An epithermal neutron zone between the fast neutron zone and the thermal neutron zone can be established for the transmutation of longlived fission products (LLFP). On July 18, 2005, the first fuel element was loaded into the Venus-Ⅰ sub-critical assembly and some preliminary experiments about the subcritical neutronics were performed. The Venus-1 can be driven by an Am-Be source or other steady neutron source (Cf-252, D-D reaction and D-T reaction) to study the effect of the external neutron source with different energies or a D-T pulsed neutron source on the dynamic characteristics.

  6. Optimisation of a high-resolution whole-body MR angiography protocol with parallel imaging and biphasic administration of a single bolus of Gd-BOPTA: preliminary experience in the systemic evaluation of atherosclerotic burden in patients referred for endovascular procedures.

    Science.gov (United States)

    Napoli, A; Anzidei, M; Marincola, B Cavallo; Zaccagna, F; Geiger, D; Di Paolo, P L; Zini, C; Catalano, C; Passariello, R

    2009-06-01

    This study was performed to validate a high-resolution whole-body magnetic resonance angiography (MRA) protocol with parallel imaging and biphasic administration of a single bolus of contrast agent in the preliminary assessment of systemic atherosclerotic burden in patients referred for endovascular procedures. Forty patients referred for endovascular treatment of atherosclerotic disease of the carotid arteries (n=23), peripheral vessels (n=14) or aorta (n=3) on the basis of previous clinical and diagnostic examinations underwent high-resolution whole-body MRA at 1.5 T with 3D spoiled gradient recalled echo (GRE) sequences, featuring parallel imaging acquisition technique with x2 acceleration factor. Sixty-eight surface coil elements and a four-station imaging protocol were employed. Biphasic intravenous administration of a paramagnetic contrast agent [gadolinium benzyloxyproprionic-tetraacetic acid (Gd-BOPTA)] was performed with the following protocol: 10 ml at a speed of 1 ml/s followed by further 10 ml at a speed of 0.5 ml/s. For image analysis, the arterial system was divided into 42 segments for evaluation. The presence or absence of atherosclerotic lesions was evaluated by two observers in consensus; segments were classified as having clinically significant disease (>or=50% stenosis or an aneurysmal dilatation) or no significant disease (<50% stenosis). The presence of stenoocclusive disease, determined at all segments, was compared with findings on digital subtraction angiography (DSA), which were interpreted by a third independent reader. Sensitivity, specificity and concordance of whole-body MRA findings with DSA were calculated, and receiver operating characteristic (ROC) analysis was performed for all vascular territories. A total of 1,680 arterial segments was evaluated; 138 (8.3%) were affected by atherosclerotic alterations. Carotid lesions were confirmed in 23 patients (34 segments), involvement of peripheral vessels in 14 (57 segments) and abdominal

  7. Rayleigh-Taylor Instability within Sediment Layers Due to Gas Retention: Preliminary Theory and Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Gauglitz, Phillip A.; Wells, Beric E.; Buchmiller, William C.; Rassat, Scot D.

    2013-03-21

    In Hanford underground waste storage tanks, a typical waste configuration is settled beds of waste particles beneath liquid layers. The settled beds are typically composed of layers, and these layers can have different physical and chemical properties. One postulated configuration within the settled bed is a less-dense layer beneath a more-dense layer. The different densities can be a result of different gas retention in the layers or different degrees of settling and compaction in the layers. This configuration can experience a Rayleigh-Taylor (RT) instability where the less dense lower layer rises into the upper layer. Previous studies of gas retention and release have not considered potential buoyant motion within a settle bed of solids. The purpose of this report is to provide a review of RT instabilities, discuss predictions of RT behavior for sediment layers, and summarize preliminary experimental observations of RT instabilities in simulant experiments.

  8. Experience with CANDID: Comparison algorithm for navigating digital image databases

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, P.; Cannon, M.

    1994-10-01

    This paper presents results from the authors experience with CANDID (Comparison Algorithm for Navigating Digital Image Databases), which was designed to facilitate image retrieval by content using a query-by-example methodology. A global signature describing the texture, shape, or color content is first computed for every image stored in a database, and a normalized similarity measure between probability density functions of feature vectors is used to match signatures. This method can be used to retrieve images from a database that are similar to a user-provided example image. Results for three test applications are included.

  9. Automatic Polyp Detection in Pillcam Colon 2 Capsule Images and Videos: Preliminary Feasibility Report

    Directory of Open Access Journals (Sweden)

    Pedro N. Figueiredo

    2011-01-01

    Full Text Available Background. The aim of this work is to present an automatic colorectal polyp detection scheme for capsule endoscopy. Methods. PillCam COLON2 capsule-based images and videos were used in our study. The database consists of full exam videos from five patients. The algorithm is based on the assumption that the polyps show up as a protrusion in the captured images and is expressed by means of a P-value, defined by geometrical features. Results. Seventeen PillCam COLON2 capsule videos are included, containing frames with polyps, flat lesions, diverticula, bubbles, and trash liquids. Polyps larger than 1 cm express a P-value higher than 2000, and 80% of the polyps show a P-value higher than 500. Diverticula, bubbles, trash liquids, and flat lesions were correctly interpreted by the algorithm as nonprotruding images. Conclusions. These preliminary results suggest that the proposed geometry-based polyp detection scheme works well, not only by allowing the detection of polyps but also by differentiating them from nonprotruding images found in the films.

  10. [The use of nitric oxide during transport of newborns with critical respiratory insufficiency: own experience, preliminary report].

    Science.gov (United States)

    Ziebiński, Marek; Walas, Wojciech

    2002-01-01

    This preliminary report presents author's experience with inhaled nitric oxide during transport of newborns with critical respiratory insufficiency. The theoretical basis, indications and contraindications as well as principles of administration during transport are described. The required equipment and some technical aspects are discussed. A short preview of performed transportations is given. Preliminary data show, that use of NO during transport is very helpful in children with critical respiratory insufficiency.

  11. RGB-NIR color image fusion: metric and psychophysical experiments

    Science.gov (United States)

    Hayes, Alex E.; Finlayson, Graham D.; Montagna, Roberto

    2015-01-01

    In this paper, we compare four methods of fusing visible RGB and near-infrared (NIR) images to produce a color output image, using a psychophysical experiment and image fusion quality metrics. The results of the psychophysical experiment show that two methods are significantly preferred to the original RGB image, and therefore RGB-NIR image fusion may be useful for photographic enhancement in those cases. The Spectral Edge method is the most preferred method, followed by the dehazing method of Schaul et al. We then investigate image fusion metrics which give results correlated with the psychophysical experiment results. We extend several existing metrics from 2 to 1 to M to N channel image fusion, as well as introducing new metrics based on output image colorfulness and contrast, and test them on our experimental data. While none of the individual metrics gives a ranking of the algorithms which exactly matches that of the psychophysical experiment, through a combination of two metrics we accurately rank the two leading fusion methods.

  12. ISPA (imaging silicon pixel array) experiment

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    The ISPA tube is a position-sensitive photon detector. It belongs to the family of hybrid photon detectors (HPD), recently developed by CERN and INFN with leading photodetector firms. HPDs confront in a vacuum envelope a photocathode and a silicon detector. This can be a single diode or a pixelized detector. The electrons generated by the photocathode are efficiently detected by the silicon anode by applying a high-voltage difference between them. ISPA tube can be used in high-energy applications as well as bio-medical and imaging applications.

  13. Nuclear imaging of the fuel assembly in ignition experiments

    Energy Technology Data Exchange (ETDEWEB)

    Grim, G. P.; Guler, N.; Merrill, F. E.; Morgan, G. L.; Danly, C. R.; Volegov, P. L.; Wilde, C. H.; Wilson, D. C.; Clark, D. S.; Hinkel, D. E.; Jones, O. S.; Raman, K. S.; Izumi, N.; Fittinghoff, D. N.; Drury, O. B.; Alger, E. T.; Arnold, P. A.; Ashabranner, R. C.; Atherton, L. J.; Barrios, M. A.; Batha, S.; Bell, P. M.; Benedetti, L. R.; Berger, R. L.; Bernstein, L. A.; Berzins, L. V.; Betti, R.; Bhandarkar, S. D.; Bionta, R. M.; Bleuel, D. L.; Boehly, T. R.; Bond, E. J.; Bowers, M. W.; Bradley, D. K.; Brunton, G. K.; Buckles, R. A.; Burkhart, S. C.; Burr, R. F.; Caggiano, J. A.; Callahan, D. A.; Casey, D. T.; Castro, C.; Celliers, P. M.; Cerjan, C. J.; Chandler, G. A.; Choate, C.; Cohen, S. J.; Collins, G. W.; Cooper, G. W.; Cox, J. R.; Cradick, J. R.; Datte, P. S.; Dewald, E. L.; Di Nicola, P.; Di Nicola, J. M.; Divol, L.; Dixit, S. N.; Dylla-Spears, R.; Dzenitis, E. G.; Eckart, M. J.; Eder, D. C.; Edgell, D. H.; Edwards, M. J.; Eggert, J. H.; Ehrlich, R. B.; Erbert, G. V.; Fair, J.; Farley, D. R.; Felker, B.; Fortner, R. J.; Frenje, J. A.; Frieders, G.; Friedrich, S.; Gatu-Johnson, M.; Gibson, C. R.; Giraldez, E.; Glebov, V. Y.; Glenn, S. M.; Glenzer, S. H.; Gururangan, G.; Haan, S. W.; Hahn, K. D.; Hammel, B. A.; Hamza, A. V.; Hartouni, E. P.; Hatarik, R.; Hatchett, S. P.; Haynam, C.; Hermann, M. R.; Herrmann, H. W.; Hicks, D. G.; Holder, J. P.; Holunga, D. M.; Horner, J. B.; Hsing, W. W.; Huang, H.; Jackson, M. C.; Jancaitis, K. S.; Kalantar, D. H.; Kauffman, R. L.; Kauffman, M. I.; Khan, S. F.; Kilkenny, J. D.; Kimbrough, J. R.; Kirkwood, R.; Kline, J. L.; Knauer, J. P.; Knittel, K. M.; Koch, J. A.; Kohut, T. R.; Kozioziemski, B. J.; Krauter, K.; Krauter, G. W.; Kritcher, A. L.; Kroll, J.; Kyrala, G. A.; Fortune, K. N. La; LaCaille, G.; Lagin, L. J.; Land, T. A.; Landen, O. L.; Larson, D. W.; Latray, D. A.; Leeper, R. J.; Lewis, T. L.; LePape, S.; Lindl, J. D.; Lowe-Webb, R. R.; Ma, T.; MacGowan, B. J.; MacKinnon, A. J.; MacPhee, A. G.; Malone, R. M.; Malsbury, T. N.; Mapoles, E.; Marshall, C. D.; Mathisen, D. G.; McKenty, P.; McNaney, J. M.; Meezan, N. B.; Michel, P.; Milovich, J. L.; Moody, J. D.; Moore, A. S.; Moran, M. J.; Moreno, K.; Moses, E. I.; Munro, D. H.; Nathan, B. R.; Nelson, A. J.; Nikroo, A.; Olson, R. E.; Orth, C.; Pak, A. E.; Palma, E. S.; Parham, T. G.; Patel, P. K.; Patterson, R. W.; Petrasso, R. D.; Prasad, R.; Ralph, J. E.; Regan, S. P.; Rinderknecht, H.; Robey, H. F.; Ross, G. F.; Ruiz, C. L.; Seguin, F. H.; Salmonson, J. D.; Sangster, T. C.; Sater, J. D.; Saunders, R. L.; Schneider, M. B.; Schneider, D. H.; Shaw, M. J.; Simanovskaia, N.; Spears, B. K.; Springer, P. T.; Stoeckl, C.; Stoeffl, W.; Suter, L. J.; Thomas, C. A.; Tommasini, R.; Town, R. P.; Traille, A. J.; Wonterghem, B. Van; Wallace, R. J.; Weaver, S.; Weber, S. V.; Wegner, P. J.; Whitman, P. K.; Widmann, K.; Widmayer, C. C.; Wood, R. D.; Young, B. K.; Zacharias, R. A.; Zylstra, A.

    2013-05-01

    First results from the analysis of neutron image data collected on implosions of cryogenically layered deuterium-tritium capsules during the 2011-2012 National Ignition Campaign are reported. The data span a variety of experimental designs aimed at increasing the stagnation pressure of the central hotspot and areal density of the surrounding fuel assembly. Images of neutrons produced by deuterium–tritium fusion reactions in the hotspot are presented, as well as images of neutrons that scatter in the surrounding dense fuel assembly. The image data are compared with 1D and 2D model predictions, and consistency checked using other diagnostic data. The results indicate that the size of the fusing hotspot is consistent with the model predictions, as well as other imaging data, while the overall size of the fuel assembly, inferred from the scattered neutron images, is systematically smaller than models’ prediction. Preliminary studies indicate these differences are consistent with a significant fraction (20%–25%) of the initial deuterium-tritium fuel mass outside the compact fuel assembly, due either to low mode mass asymmetry or high mode 3D mix effects at the ablator-ice interface.

  14. Use of Diffusion Spectrum imaging in preliminary longitudinal evaluation of Amyotrophic Lateral Sclerosis: development of an imaging biomarker

    Directory of Open Access Journals (Sweden)

    Kumar eAbhinav

    2014-04-01

    Full Text Available Previous diffusion tensor imaging (DTI studies have shown white matter pathology in ALS, predominantly in the motor pathways. Further these studies have shown that DTI can be used longitudinally to track pathology over time, making white matter pathology a candidate as an outcome measure in future trials. DTI has demonstrated application in group studies, however its derived indices, for example fractional anisotropy, are susceptible to partial volume effects, making its role questionable in examining individual progression. We hypothesize that changes in the white matter are present in ALS beyond the motor tracts, and that the affected pathways and associated pattern of disease progression can be tracked longitudinally using automated diffusion connectometry analysis. Connectometry analysis is based on diffusion spectrum imaging (DSI and overcomes the limitations of a conventional tractography approach and DTI. The identified affected white matter tracts can then be assessed in a targeted fashion using High definition fiber tractography (a novel white matter MR imaging technique. Changes in quantitative and qualitative markers over time could then be correlated with clinical progression.We illustrate these principles towards developing an imaging biomarker for demonstrating individual progression, by presenting results for five ALS patients, including with longitudinal data in two. Preliminary analysis demonstrated a number of changes bilaterally and asymmetrically in motoric and extramotoric white matter pathways. Further the limbic system was also affected possibly explaining the cognitive symptoms in ALS. In the two longitudinal subjects, the white matter changes were less extensive at baseline, although there was evidence of disease progression in a frontal pattern with a relatively spared postcentral gyrus, consistent with the known pathology in ALS.

  15. Preliminary test of effects of cognitive ability, experience, and teaching methods on Verbal Analogy Test scores.

    Science.gov (United States)

    Rosenberg, D; Willson-Quayle, A; Pasnak, R

    2000-06-01

    The methods from which one can choose when preparing for the GRE Verbal Analogies include books, software, audiotapes, and formal classroom instruction. What teaching method will work best for a given individual? To begin the search for an answer, Gray's test of reasoning ability was given to 28 undergraduates who also answered a questionnaire detailing their experience with analogies. They were randomly assigned to teaching conditions ranging from self-directed workbook study to intensive interactive assistance. No teaching method was superior overall, but interactions showed that (1) students who scored worst on the pretest improved the most, (2) those higher in cognitive functioning and experience performed better after intensive interactive assistance, and (3) those lower in both cognitive functioning and experience did significantly better with self-paced workbooks. This preliminary work suggests that it may be profitable to assess the prior experience and reasoning of potential students and adopt the methods for teaching formal operational thought found empirically to be most suitable.

  16. Preliminary Results from the PrimEx-II experiment at Jefferson Lab

    Energy Technology Data Exchange (ETDEWEB)

    Gasparian, Ashot [NCA& T, Greensboro, NC; Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)

    2016-06-01

    Properties of the neutral pion, as the lightest hadron in Nature, are most sensitive to the basic symmetries and their partial breaking effects in the theory of the strong interaction (QCD). In particular, the po →gg decay width is primarily defined by the spontaneous chiral symmetry breaking effect (chiral anomaly) in QCD. The next order corrections to the anomaly have been shown to be small and are known to a 1% precision level. The PrimEx Collaboration at JLab has developed and performed two Primakoff type experiments to measure the po →gg decay width with a similar precision. The published result from the PrimEx-I experiment, G(p0 →gg ) = 7.82±0.14 (stat.)±0.17 (syst.) eV, was a factor of two more precise than the average value quoted in PDG-2010 [1]. The second experiment was performed in 2010 with a goal of 1.4% total uncertainty to address the next-to-leading-order theory calculations. The preliminary results from the PrimEx-II experiment are presented and discussed in this note.

  17. Coherence Imaging Measurements of Impurity Flow in the Compact Toroidal Hybrid Experiment

    Science.gov (United States)

    Ennis, D. A.; Hartwell, G. J.; Johnson, C. A.; Maurer, D. A.; Allen, S. L.; Meyer, W. H.; Samuell, C. M.

    2016-10-01

    Measurements of impurity ion emissivity and velocity in the Compact Toroidal Hybrid (CTH) experiment are achieved with a new optical coherence imaging diagnostic. The Coherence Imaging Spectroscopy (CIS) technique measures the spectral coherence of an emission line with an imaging interferometer of fixed delay. CIS has a number of advantages when compared to dispersive Doppler spectroscopy, including higher throughput and the capability to provide 2D spectral images, making it ideal for investigating the non-axisymmetric geometry of CTH plasmas. Furthermore, detailed measurements of the ion flow structure provided by CIS combined with predictive computational models could also provide spatially resolved images of complex flow structures, such as those associated with an island divertor. First CIS measurements of CTH plasmas reveal strong signals for C III (465 nm), He II (468 nm) and C II (513 nm) emission. Preliminary analysis of C III interferograms indicate a net toroidal flow on the order of 10 km/s during the time of peak current. Bench tests using Zn and Cd light sources reveal that the temperature of the instrument must be actively controlled to within 0.01°C to limit phase drift of the interferometer resulting in artificially measured flow. Results from this diagnostic will aid in characterizing the ion flow in planned island divertor and MHD mode-locking experiments. Work supported by USDoE Grant DE-FG02-00ER54610.

  18. Preliminary Results of Earthquake-Induced Building Damage Detection with Object-Based Image Classification

    Science.gov (United States)

    Sabuncu, A.; Uca Avci, Z. D.; Sunar, F.

    2016-06-01

    Earthquakes are the most destructive natural disasters, which result in massive loss of life, infrastructure damages and financial losses. Earthquake-induced building damage detection is a very important step after earthquakes since earthquake-induced building damage is one of the most critical threats to cities and countries in terms of the area of damage, rate of collapsed buildings, the damage grade near the epicenters and also building damage types for all constructions. Van-Ercis (Turkey) earthquake (Mw= 7.1) was occurred on October 23th, 2011; at 10:41 UTC (13:41 local time) centered at 38.75 N 43.36 E that places the epicenter about 30 kilometers northern part of the city of Van. It is recorded that, 604 people died and approximately 4000 buildings collapsed or seriously damaged by the earthquake. In this study, high-resolution satellite images of Van-Ercis, acquired by Quickbird-2 (Digital Globe Inc.) after the earthquake, were used to detect the debris areas using an object-based image classification. Two different land surfaces, having homogeneous and heterogeneous land covers, were selected as case study areas. As a first step of the object-based image processing, segmentation was applied with a convenient scale parameter and homogeneity criterion parameters. As a next step, condition based classification was used. In the final step of this preliminary study, outputs were compared with streetview/ortophotos for the verification and evaluation of the classification accuracy.

  19. Cortical gyrification in autistic and Asperger disorders: a preliminary magnetic resonance imaging study.

    Science.gov (United States)

    Jou, Roger J; Minshew, Nancy J; Keshavan, Matcheri S; Hardan, Antonio Y

    2010-12-01

    The validity of Asperger disorder as a distinct syndrome from autism is unclear partly because of the paucity of differentiating neurobiological evidence. Frontal lobe cortical folding between these disorders was compared using the gyrification index. Twenty-three boys underwent structural magnetic resonance imaging: 6 with high-functioning autism, 9 with Asperger disorder, and 8 controls. Using the first coronal slice anterior to the corpus callosum, total and outer cortical contours were traced to calculate the gyrification index. This index was also calculated for superior and inferior regions to examine dorsolateral prefrontal and orbitofrontal cortices, respectively. Analysis of variance revealed differences in the left inferior gyrification index, which was higher in the autism group compared with Asperger and control groups. There were no differences in age, intelligence quotient, and brain volume. These preliminary findings suggest that cortical folding may be abnormally high in the frontal lobe in autism but not Asperger disorder, suggesting distinct frontal lobe neuropathology.

  20. Preliminary results of absolute wavelength calibration of imaging X-ray crystal spectrometer on EAST

    Energy Technology Data Exchange (ETDEWEB)

    Pan, Xiayun [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); University of Science and Technology of China, Hefei 230026 (China); Wang, Fudi [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Chen, Jun [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); University of Science and Technology of China, Hefei 230026 (China); Lyu, Bo, E-mail: blu@ipp.ac.cn [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Li, Yingying; Fu, Jia; Xu, Liqing [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Shi, Yuejiang [University of Science and Technology of China, Hefei 230026 (China); Department of Nuclear Engineering, Seoul National University, Seoul 151-742 (Korea, Republic of); Ye, Minyou [University of Science and Technology of China, Hefei 230026 (China); Wan, Baonian [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China)

    2015-10-15

    Highlights: • The absolute wavelength calibration method for X-ray crystal spectrometer using X-ray fluorescence of the appropriate materials was first tested on EAST, and the preliminary experimental results were obtained. • The experimental results were thoroughly discussed and suggestion for further improvements of the experimental arrangement was proposed. • Rotation calibration of X-ray crystal spectrometer on EAST using MHD frequency was presented when the absolute wavelength calibration method is unavailable currently. - Abstract: Imaging X-ray crystal spectrometers (XCS) are currently operating on several major tokamaks to provide profiles of ion temperature and rotation velocity. In order to acquire absolute rotation velocity, several indirect methods were pursued previously, however the direct and effective method is to use known X-ray lines for wavelength calibration. One way to produce standard spectral lines is X-ray fluorescence, which could be excited by X-rays from tokamak plasmas. As part of the upgrade of XCS system on EAST, wavelength calibration was studied using cadmium's L-shell lines, namely Lα{sub 1} line (3.9564 Å) and Lα{sub 2} line (3.9650 Å) as the reference wavelength. The Geant 4 code was used to optimize foil thickness to achieve a reasonable X-ray fluorescence intensity. The Cd foil was placed between the beryllium window and crystal and could be retracted to provide in situ wavelength calibration. The detailed arrangement and preliminary wavelength calibration results of imaging X-ray crystal spectrometer on EAST are presented, plus the calibration using MHD frequency.

  1. HACCP and water safety plans in Icelandic water supply: preliminary evaluation of experience.

    Science.gov (United States)

    Gunnarsdóttir, María J; Gissurarson, Loftur R

    2008-09-01

    Icelandic waterworks first began implementing hazard analysis and critical control points (HACCP) as a preventive approach for water safety management in 1997. Since then implementation has been ongoing and currently about 68% of the Icelandic population enjoy drinking water from waterworks with a water safety plan based on HACCP. Preliminary evaluation of the success of HACCP implementation was undertaken in association with some of the waterworks that had implemented HACCP. The evaluation revealed that compliance with drinking water quality standards improved considerably following the implementation of HACCP. In response to their findings, waterworks implemented a large number of corrective actions to improve water safety. The study revealed some limitations for some, but not all, waterworks in relation to inadequate external and internal auditing and a lack of oversight by health authorities. Future studies should entail a more comprehensive study of the experience with the use of HACCP with the purpose of developing tools to promote continuing success.

  2. Experiments, conceptual design, preliminary cost estimates and schedules for an underground research facility

    Energy Technology Data Exchange (ETDEWEB)

    Korbin, G.; Wollenberg, H.; Wilson, C.; Strisower, B.; Chan, T.; Wedge, D.

    1981-09-01

    Plans for an underground research facility are presented, incorporating techniques to assess the hydrological and thermomechanical response of a rock mass to the introduction and long-term isolation of radioactive waste, and to assess the effects of excavation on the hydrologic integrity of a repository and its subsequent backfill, plugging, and sealing. The project is designed to utilize existing mine or civil works for access to experimental areas and is estimated to last 8 years at a total cost for contruction and operation of $39.0 million (1981 dollars). Performing the same experiments in an existing underground research facility would reduce the duration to 7-1/2 years and cost $27.7 million as a lower-bound estimate. These preliminary plans and estimates should be revised after specific sites are identified which would accommodate the facility.

  3. Post-depositional changes in snow isotope content: preliminary results of laboratory experiments

    Directory of Open Access Journals (Sweden)

    A. A. Ekaykin

    2009-10-01

    Full Text Available Isotopic content of the snow and firn thickness is assumed to be altered significantly due to the post-depositional (PD mass- and isotope exchange with the atmospheric water vapor. If so, these effects should be accounted for in the ice core-based isotope-temperature paleo-reconstructions. In order to study the intensity of the PD processes we set up a series of laboratory experiments. In this paper we describe in detail the experimental technique and briefly overview preliminary results. It is shown that the PD modifications in the upper layer of snow thickness are noticeably strong even under such a low temperature as −35°C (the value typical for the Central Antarctic summer. It is demonstrated that the PD isotopic changes in snow can be approximated as a linear function of the relative mass loss due to snow sublimation. Possible applications for improving the isotope-temperature paleo-reconstructions are shortly discussed.

  4. From image quality to atmosphere experience: how evolutions in technology impact experience assessment

    Science.gov (United States)

    Heynderickx, Ingrid; de Ridder, Huib

    2013-03-01

    Image quality is a concept that for long very well served to optimize display performance and signal quality. New technological developments, however, forced the community to look into higher-level concepts to capture the full experience. Terms as naturalness and viewing experience were used to optimize the full experience of 3D-displays and Ambilight TV. These higher-level concepts capture differences in image quality and differences in perceived depth or perceived viewing field. With the introduction of solid-state lighting, further enhancing the multimedia experience, yet more advanced quality evaluation concepts to optimize the overall experience will be needed in the future.

  5. Preliminary Experience with a New Multidirectional Videoendoscope for Neuroendoscopic Surgical Procedures.

    Directory of Open Access Journals (Sweden)

    Luigi Maria Cavallo

    Full Text Available We assessed the applicability of a new multidirectional videoendoscope (digiCAMeleon, Karl Storz GmbH, Tuttlingen, Germany in various neuroendoscopic procedures.A 4-mm-diameter rigid videoendoscope (digiCAMeleon, Karl Storz GmbH, Tuttlingen, Germany with 1 sensor and an internal LED light source was tested. The device offers a resolution of 1920 x 1080 pixels and weighs ≈ 215 g. The prototype was tested on three cadaveric heads using three different approaches: a endoscopic endonasal transsphenoidal; b frontal transcortical intraventricular; c supraorbital.We identified several major benefits of the integrated system as applied to endoscopic endonasal, transcortical intraventricular, and endoscopic supraorbital keyhole approaches. These included improved maneuverability of the scope on account of reduced bulk and integration of the camera and fiberoptic light components, a variable angle of view from 0-70 degrees, and a novel feature that can be activated to maintain orientation of the surgical horizon. Our preliminary report highlights the potential for handling the videoendoscope in one hand, as one would a microsurgical instrument. The videoendoscope harbors all its electronic and lighting data into a unique and thin cable, thus resembling a modern "all-in-one" computer technology. Because of its reduced weight and ergonomic shape, controlling its movements is very easy and comfortable, even in the microsurgical environment. Furthermore, the videoendoscope offers the unique feature of orienting the horizon of vision, thanks to the possibility of offering angled views while working; this helps the surgeons to stay oriented with direct visualization and improved control of the instruments over a specific area of interest.The videoendoscope prototype represents an HD-image quality versatile tool in a neurosurgical environment, thanks to its reduced weight and dimensions; in these preliminary simulations, we have identified optimized visibility

  6. Preliminary Experience with a New Multidirectional Videoendoscope for Neuroendoscopic Surgical Procedures

    Science.gov (United States)

    Cavallo, Luigi Maria; Di Somma, Alberto; Solari, Domenico; de Divitiis, Oreste; Bracale, Umberto Marcello; Cappabianca, Paolo

    2016-01-01

    Purpose We assessed the applicability of a new multidirectional videoendoscope (digiCAMeleon, Karl Storz GmbH, Tuttlingen, Germany) in various neuroendoscopic procedures. Methods A 4-mm-diameter rigid videoendoscope (digiCAMeleon, Karl Storz GmbH, Tuttlingen, Germany) with 1 sensor and an internal LED light source was tested. The device offers a resolution of 1920 x 1080 pixels and weighs ≈ 215 g. The prototype was tested on three cadaveric heads using three different approaches: a) endoscopic endonasal transsphenoidal; b) frontal transcortical intraventricular; c) supraorbital. Results We identified several major benefits of the integrated system as applied to endoscopic endonasal, transcortical intraventricular, and endoscopic supraorbital keyhole approaches. These included improved maneuverability of the scope on account of reduced bulk and integration of the camera and fiberoptic light components, a variable angle of view from 0–70 degrees, and a novel feature that can be activated to maintain orientation of the surgical horizon. Our preliminary report highlights the potential for handling the videoendoscope in one hand, as one would a microsurgical instrument. The videoendoscope harbors all its electronic and lighting data into a unique and thin cable, thus resembling a modern "all-in-one" computer technology. Because of its reduced weight and ergonomic shape, controlling its movements is very easy and comfortable, even in the microsurgical environment. Furthermore, the videoendoscope offers the unique feature of orienting the horizon of vision, thanks to the possibility of offering angled views while working; this helps the surgeons to stay oriented with direct visualization and improved control of the instruments over a specific area of interest. Conclusions The videoendoscope prototype represents an HD-image quality versatile tool in a neurosurgical environment, thanks to its reduced weight and dimensions; in these preliminary simulations, we have

  7. Screening diagnostics of antivital experiences and propensity toward impulsive, autoagressive behavior in adolescents (preliminary results

    Directory of Open Access Journals (Sweden)

    Bannikov G.S.,

    2014-08-01

    Full Text Available Development of methods for revealing antivital experiences and propensity to autoaggressive behavior in educational institutions is one of the key steps in developing strategies for the primary prevention of suicidal behavior in adolescents. The purpose of this study was to develop an effective screening diagnostic package aimed at identifying antivital experiences and propensity to autoaggressive behavior. The survey methods we used were: Beck Hopelessness Scale, Russell Loneliness Scale, A.G. Shmelev Suicide Risk Questionnaire, PDQ-IV Borderline disorder and Narcissism scales. At the first stage we examined 750 minors aged 12-18 and identified risk group (85 people – 11.4%, which included adolescents with high levels of both individual scales, and their combination. At the second stage we examined 10 adolescents at risk. In 7 of them (70% were identified antivital, suicidal thoughts of passive or compulsive nature, signs of subjective and objective socio- psychological maladjustment. Our preliminary conclusion is that high levels of hopelessness and loneliness in adolescents are stable predictors of mental and emotional distress and psychosocial maladjustment in the period of psychological crises and decompensation of character accentuation of borderline and narcissistic types. These scales can be recommended for primary screening of antivital (depressive experiences and propensity to autoaggressive behavior in adolescents.

  8. Compressive sensing in reflectance confocal microscopy of skin images: a preliminary comparative study

    Science.gov (United States)

    Arias, Fernando X.; Sierra, Heidy; Rajadhyaksha, Milind; Arzuaga, Emmanuel

    2016-03-01

    Compressive Sensing (CS)-based technologies have shown potential to improve the efficiency of acquisition, manipulation, analysis and storage processes on signals and imagery with slight discernible loss in data performance. The CS framework relies on the reconstruction of signals that are presumed sparse in some domain, from a significantly small data collection of linear projections of the signal of interest. As a result, a solution to the underdetermined linear system resulting from this paradigm makes it possible to estimate the original signal with high accuracy. One common approach to solve the linear system is based on methods that minimize the L1-norm. Several fast algorithms have been developed for this purpose. This paper presents a study on the use of CS in high-resolution reflectance confocal microscopy (RCM) images of the skin. RCM offers a cell resolution level similar to that used in histology to identify cellular patterns for diagnosis of skin diseases. However, imaging of large areas (required for effective clinical evaluation) at such high-resolution can turn image capturing, processing and storage processes into a time consuming procedure, which may pose a limitation for use in clinical settings. We present an analysis on the compression ratio that may allow for a simpler capturing approach while reconstructing the required cellular resolution for clinical use. We provide a comparative study in compressive sensing and estimate its effectiveness in terms of compression ratio vs. image reconstruction accuracy. Preliminary results show that by using as little as 25% of the original number of samples, cellular resolution may be reconstructed with high accuracy.

  9. A preliminary investigation: the impact of microscopic condenser on depth of field in cytogenetic imaging

    Science.gov (United States)

    Ren, Liqiang; Qiu, Yuchen; Li, Zheng; Li, Yuhua; Zheng, Bin; Li, Shibo; Chen, Wei R.; Liu, Hong

    2013-02-01

    As one of the important components of optical microscopes, the condenser has a considerable impact on system performance, especially on the depth of field (DOF). DOF is a critical technical feature in cytogenetic imaging that may affect the efficiency and accuracy of clinical diagnosis. The purpose of this study is to investigate the influence of microscopic condenser on DOF using a prototype of transmitted optical microscope, based on objective and subjective evaluations. After the description of the relationship between condenser and objective lens and the theoretical analysis of the condenser impact on system numerical aperture and DOF, a standard resolution pattern and several cytogenetic samples are adopted to assess the condenser impact on DOF, respectively. The experimental results of these objective and subjective evaluations are in agreement with the theoretical analysis and show that, under the specific intermediate range of condenser numerical aperture ( NAcond ), the DOF value decreases with the increase of NAcond . Although the above qualitative results are obtained under the experimental conditions with a specific prototype system, the methods presented in this preliminary investigation could offer useful guidelines for optimizing operational parameters in cytogenetic imaging.

  10. Visualizing aerosol-particle injection for diffractive-imaging experiments

    CERN Document Server

    Awel, Salah; Eckerskorn, Niko; Wiedorn, Max; Horke, Daniel A; Rode, Andrei V; Küpper, Jochen; Chapman, Henry N

    2015-01-01

    Delivering sub-micrometer particles to an intense x-ray focus is a crucial aspect of single-particle diffractive-imaging experiments at x-ray free-electron lasers. Enabling direct visualization of sub-micrometer aerosol particle streams without interfering with the operation of the particle injector can greatly improve the overall efficiency of single-particle imaging experiments by reducing the amount of time and sample consumed during measurements. We have developed in-situ non-destructive imaging diagnostics to aid real-time particle injector optimization and x-ray/particle-beam alignment, based on laser illumination schemes and fast imaging detectors. Our diagnostics are constructed to provide a non-invasive rapid feedback on injector performance during measurements, and have been demonstrated during diffraction measurements at the FLASH free-electron laser.

  11. Developing students’ ideas about lens imaging: teaching experiments with an image-based approach

    Science.gov (United States)

    Grusche, Sascha

    2017-07-01

    Lens imaging is a classic topic in physics education. To guide students from their holistic viewpoint to the scientists’ analytic viewpoint, an image-based approach to lens imaging has recently been proposed. To study the effect of the image-based approach on undergraduate students’ ideas, teaching experiments are performed and evaluated using qualitative content analysis. Some of the students’ ideas have not been reported before, namely those related to blurry lens images, and those developed by the proposed teaching approach. To describe learning pathways systematically, a conception-versus-time coordinate system is introduced, specifying how teaching actions help students advance toward a scientific understanding.

  12. The Shuttle Imaging Radar B (SIR-B) experiment report

    Science.gov (United States)

    Cimino, Jo Bea; Holt, Benjamin; Richardson, Annie

    1988-01-01

    The primary objective of the SIR-B experiment was to acquire multiple-incidence-angle radar imagery of a variety of Earth's surfaces to better understand the effects of imaging geometry on radar backscatter. A complementary objective was to map extensive regions of particular interest. Under these broad objectives, many specific scientific experiments were defined by the 43 SIR-B Science Team members, including studies in the area of geology, vegetation, radar penetration, oceanography, image analysis, and calibration technique development. Approximately 20 percent of the planned digital data were collected, meeting 40 percent of the scientific objectives. This report is an overview of the SIR-B experiment and includes the science investigations, hardware design, mission scenario, mission operations, events of the actual missions, astronaut participation, data products (including auxiliary data), calibrations, and a summary of the actual coverage. Also included are several image samples.

  13. Preliminary experience with dexmedetomidine for monitored anesthesia care during ENT surgical procedures.

    Science.gov (United States)

    Busick, Tamra; Kussman, Mary; Scheidt, Troy; Tobias, Joseph D

    2008-01-01

    Dexmedetomidine is an alpha2-adrenergic agonist that produces anxiolysis, amnesia, sedation, potentiation of opioid analgesia, and sympatholysis. It is currently approved by the U.S. Food & Drug Administration for the sedation of adults in the intensive care setting for up to 24 hours during mechanical ventilation. Given its beneficial sedative and anxiolytic properties and limited adverse effect profile, it has been used in several other clinical scenarios. The authors present their experience using dexmedetomidine for monitored anesthesia care (MAC) during "awake" ENT procedures such as thyroplasty, a procedure requiring a patient to verbalize when requested but to otherwise remain immobile to allow for completion of the procedure, and in a patient with post-polio syndrome with poor pulmonary reserve requiring esophagoscopy with dilation and botulinum toxin injection for cricopharyngeal dysfunction. Our preliminary experience suggests that dexmedetomidine provides effective sedation as the primary agent for MAC during such procedures in adult patients. The end-organ effects of dexmedetomidine and previous reports of its use during MAC are reviewed.

  14. Augmented Reality Cubes for Cognitive Gaming: Preliminary Usability and Game Experience Testing

    Directory of Open Access Journals (Sweden)

    Costas Boletsis

    2016-03-01

    Full Text Available Early detection is important in dementia care; however, cognitive impairment is still under-recognised and under-diagnosed. Cognitive screening and training are two important preventative treatments, which can lead to early detection of cognitive decline. In this work, the “Cognitive Augmented Reality Cubes” (CogARC system is presented, i.e. a serious game for cognitive training and screening, utilising an interaction technique based on Augmented Reality and the manipulation of tangible, physical objects (cubes. The game is a collection of cognitive mini-games of preventative nature and is, primarily, targeting elderly players (≥60 years old. A preliminary testing was conducted focusing on the game experience that CogARC offers (utilising the In-Game Experience Questionnaire, the usability of the system (using the System Usability Scale, and the specific user observations and remarks, as documented by open, semi-structured interviews.  Overall, CogARC demonstrated satisfying positive responses, however, the negative reactions indicated that there are specific problems with aspects of the interaction technique and a number of mini-games. The open interview shed more light on the specific issues of each mini-game and further interpretation of user interactions. The current study managed to provide interesting insights into the game design elements, integration of Augmented Reality, tangible interaction of the system, and on how elderly players perceive and use those interaction components. 

  15. Preliminary experience with the MicroMed DeBakey pediatric ventricular assist device.

    Science.gov (United States)

    Fraser, Charles D; Carberry, Kathleen E; Owens, W Richard; Arrington, Karol A; Morales, David L S; Heinle, Jeffery S; McKenzie, E Dean

    2006-01-01

    Mechanical circulatory support for both acute and chronic heart failure is a widely applied therapeutic option in the adult population with a variety of devices clinically available. Technology in this field has advanced sufficiently such that long-term support or "destination therapy" has become a generally accepted reality. Similar progress has not occurred in the field of device support for heart failure in children. While the number of potential patients is significantly lower in the pediatric population, the clinical relevance and poignancy of individual need are nonetheless real. Until recently, children with heart failure have been largely disadvantaged in comparison to their adult counterparts. The DeBakey VAD Child (MicroMed Technology, Inc, Houston, TX) represents a hopeful initial step in the direction of reducing the technological gap between adults and children. While the clinical experience with this device is limited at present, preliminary results are encouraging. This report will provide an overview of the DeBakey VAD Child, including device specifications, indications for clinical use, surgical and postoperative considerations, and updated clinical experience.

  16. Results from neutron imaging of ICF experiments at NIF

    Science.gov (United States)

    Merrill, F. E.; Danly, C. R.; Fittinghoff, D. N.; Grim, G. P.; Guler, N.; Volegov, P. L.; Wilde, C. H.

    2016-03-01

    In 2011 a neutron imaging diagnostic was commissioned at the National Ignition Facility (NIF). This new system has been used to collect neutron images to measure the size and shape of the burning DT plasma and the surrounding fuel assembly. The imaging technique uses a pinhole neutron aperture placed between the neutron source and a neutron detector. The detection system measures the two-dimensional distribution of neutrons passing through the pinhole. This diagnostic collects two images at two times. The long flight path for this diagnostic, 28 m, results in a chromatic separation of the neutrons, allowing the independently timed images to measure the source distribution for two neutron energies. Typically one image measures the distribution of the 14 MeV neutrons, and the other image measures the distribution of the 6-12 MeV neutrons. The combination of these two images has provided data on the size and shape of the burning plasma within the compressed capsule, as well as a measure of the quantity and spatial distribution of the cold fuel surrounding this core. Images have been collected for the majority of the experiments performed as part of the ignition campaign. Results from this data have been used to estimate a burn-averaged fuel assembly as well as providing performance metrics to gauge progress towards ignition. This data set and our interpretation are presented.

  17. Predicting diagnostic error in radiology via eye-tracking and image analytics: Preliminary investigation in mammography

    Energy Technology Data Exchange (ETDEWEB)

    Voisin, Sophie; Tourassi, Georgia D. [Biomedical Science and Engineering Center, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831 (United States); Pinto, Frank [School of Engineering, Science, and Technology, Virginia State University, Petersburg, Virginia 23806 (United States); Morin-Ducote, Garnetta; Hudson, Kathleen B. [Department of Radiology, University of Tennessee Medical Center at Knoxville, Knoxville, Tennessee 37920 (United States)

    2013-10-15

    Purpose: The primary aim of the present study was to test the feasibility of predicting diagnostic errors in mammography by merging radiologists’ gaze behavior and image characteristics. A secondary aim was to investigate group-based and personalized predictive models for radiologists of variable experience levels.Methods: The study was performed for the clinical task of assessing the likelihood of malignancy of mammographic masses. Eye-tracking data and diagnostic decisions for 40 cases were acquired from four Radiology residents and two breast imaging experts as part of an IRB-approved pilot study. Gaze behavior features were extracted from the eye-tracking data. Computer-generated and BIRADS images features were extracted from the images. Finally, machine learning algorithms were used to merge gaze and image features for predicting human error. Feature selection was thoroughly explored to determine the relative contribution of the various features. Group-based and personalized user modeling was also investigated.Results: Machine learning can be used to predict diagnostic error by merging gaze behavior characteristics from the radiologist and textural characteristics from the image under review. Leveraging data collected from multiple readers produced a reasonable group model [area under the ROC curve (AUC) = 0.792 ± 0.030]. Personalized user modeling was far more accurate for the more experienced readers (AUC = 0.837 ± 0.029) than for the less experienced ones (AUC = 0.667 ± 0.099). The best performing group-based and personalized predictive models involved combinations of both gaze and image features.Conclusions: Diagnostic errors in mammography can be predicted to a good extent by leveraging the radiologists’ gaze behavior and image content.

  18. CT-guided thin needles percutaneous cryoablation (PCA) in patients with primary and secondary lung tumors: A preliminary experience

    Energy Technology Data Exchange (ETDEWEB)

    Pusceddu, Claudio, E-mail: clapusceddu@gmail.com [Division of Interventional Radiology, Department of Oncological Radiology, Businco Hospital, Regional Referral Center for Oncologic Diseases, Cagliari, Zip code 09100 (Italy); Sotgia, Barbara, E-mail: barbara.sotgia@gmail.com [Department of Oncological Radiology, Businco Hospital, Regional Referral Center for Oncological Diseases, Cagliari, Zip code 09100 (Italy); Fele, Rosa Maria, E-mail: rosellafele@tiscali.it [Department of Oncological Radiology, Businco Hospital, Regional Referral Center for Oncological Diseases, Cagliari, Zip code 09100 (Italy); Melis, Luca, E-mail: doclucamelis@tiscali.it [Department of Oncological Radiology, Businco Hospital, Regional Referral Center for Oncological Diseases, Cagliari, Zip code 09100 (Italy)

    2013-05-15

    Purpose: To report the data of our initial experience with CT-guided thin cryoprobes for percutaneous cryoablation (PCA) in patients with primary and secondary pulmonary tumors. Material and methods: CT-guided thin needles PCA was performed on 34 lung masses (11 NSCLC = 32%; 23 secondary lung malignancies = 68%) in 32 consecutive patients (24 men and 8 women; mean age 67 ± 10 years) not suitable for surgical resection. Lung masses were treated using two types of cryoprobes: IceRod and IceSeed able to obtain different size of iceball. The number of probes used ranged from 1 to 5 depending on the size of the tumor. After insertion of the cryoprobes into the lesion, the PCA were performed with two 2 (91%) or 3 (9%) cycles each of 12 min of freezing followed by a 4 min active thawing phase and a 4 min passive thawing phase for each one for all treatments. Results: All cryoablation sessions were successfully completed. All primary and metastatic lung tumors were ablated. No procedure-related deaths occurred. Morbidity consisted of 21% (7 of 34) pneumothorax and 3% (1 of 34) cases asymptomatic small pulmonary hemorrhage, respectively, all of CTCAE grade 1 (Common Terminology Criteria for Adverse Events). Low density of entire lesion, central necrosis and solid mass appearance were identify in 21 (62%), 7 (21%) and 6 (17%) of cryoablated tumors, respectively. No lymphadenopathy developed in the region of treated lesions. Technical success (complete lack of enhancement) was achieved in 82%, 97% and 91% of treated lesions at 1-, 3- and 6-months CT follow-up scan, respectively (p < .000). Comparing the tumor longest diameter between the baseline and at 6 month CT images, technical success was revealed in 92% cases (p < .000). Conclusion: Our preliminary experience suggests that PCA is a feasible treatment option. Well-designed clinical trials with a larger patient population are necessary to further investigate the long-term results and prognostic factors.

  19. Preliminary Flight Results of the Microelectronics and Photonics Test Bed: NASA DR1773 Fiber Optic Data Bus Experiment

    Science.gov (United States)

    Jackson, George L.; LaBel, Kenneth A.; Marshall, Cheryl; Barth, Janet; Seidleck, Christina; Marshall, Paul

    1998-01-01

    NASA Goddard Spare Flight Center's (GSFC) Dual Rate 1773 (DR1773) Experiment on the Microelectronic and Photonic Test Bed (MPTB) has provided valuable information on the performance of the AS 1773 fiber optic data bus in the space radiation environment. Correlation of preliminary experiment data to ground based radiation test results show the AS 1773 bus is employable in future spacecraft applications requiring radiation tolerant communication links.

  20. Automated analysis of whole skeletal muscle for muscular atrophy detection of ALS in whole-body CT images: preliminary study

    Science.gov (United States)

    Kamiya, Naoki; Ieda, Kosuke; Zhou, Xiangrong; Yamada, Megumi; Kato, Hiroki; Muramatsu, Chisako; Hara, Takeshi; Miyoshi, Toshiharu; Inuzuka, Takashi; Matsuo, Masayuki; Fujita, Hiroshi

    2017-03-01

    Amyotrophic lateral sclerosis (ALS) causes functional disorders such as difficulty in breathing and swallowing through the atrophy of voluntary muscles. ALS in its early stages is difficult to diagnose because of the difficulty in differentiating it from other muscular diseases. In addition, image inspection methods for aggressive diagnosis for ALS have not yet been established. The purpose of this study is to develop an automatic analysis system of the whole skeletal muscle to support the early differential diagnosis of ALS using whole-body CT images. In this study, the muscular atrophy parts including ALS patients are automatically identified by recognizing and segmenting whole skeletal muscle in the preliminary steps. First, the skeleton is identified by its gray value information. Second, the initial area of the body cavity is recognized by the deformation of the thoracic cavity based on the anatomical segmented skeleton. Third, the abdominal cavity boundary is recognized using ABM for precisely recognizing the body cavity. The body cavity is precisely recognized by non-rigid registration method based on the reference points of the abdominal cavity boundary. Fourth, the whole skeletal muscle is recognized by excluding the skeleton, the body cavity, and the subcutaneous fat. Additionally, the areas of muscular atrophy including ALS patients are automatically identified by comparison of the muscle mass. The experiments were carried out for ten cases with abnormality in the skeletal muscle. Global recognition and segmentation of the whole skeletal muscle were well realized in eight cases. Moreover, the areas of muscular atrophy including ALS patients were well identified in the lower limbs. As a result, this study indicated the basic technology to detect the muscle atrophy including ALS. In the future, it will be necessary to consider methods to differentiate other kinds of muscular atrophy as well as the clinical application of this detection method for early ALS

  1. Magnetospheric Atmospheric X-ray Imaging Experiment (MAXIE)

    Science.gov (United States)

    Imhof, W. L.; Voss, H. D.; Mobilia, J.; Datlowe, D. W.; Chinn, V. L.; Hilsenrath, M.; Vondrak, R. R.

    1996-01-01

    This report summarizes the activities sponsored by the Office of Naval Research for the Magnetospheric Atmospheric X-ray Imaging Experiment (MAXIE). The MAXIE instrument was developed as a joint activity of Lockheed, The Aerospace Corporation, and the University of Bergen, Norway. Lockheed was responsible for the overall management of the program, interfacing with the appropriate government agencies, the overall electrical and mechanical design, flight software, environmental testing, spacecraft integration activities, on orbit checkout, and data processing activities. The Magnetospheric Atmospheric X-ray Imaging Experiment (MAXIE), the ONR 401 experiment, is the first in a new class of satellite-borne remote sensing instruments. The primary innovation is the ability to obtain rapid, sequential, images with high sensitivity of the earth's X ray aurora from a low altitude polar orbiting satellite. These images can be used to identify dynamic temporal variations in the three-dimensional (energy and position) distribution of electron precipitation into the atmosphere. MAXIE was launched on the TIROS NOAA-13 satellite on 9 August 1993. The experiment performed well during its turn-on sequence; however, the spacecraft bus failed on 21 August 1993. New spacebased technologies successfully used in MAXIE were mixed-mode ASIC microcircuits, a zero torque scanning system with associated viscoelastic damping, a paraffin stow release mechanism, a parallel integrating PHA processor, a low noise Si(Li) sensor telescope, and an advanced thermal cooling system. MAXIE's on orbit operation, control of penetrating particle backgrounds, and scientific data indicated good overall performance.

  2. Magnetic resonance imaging features of the spinal cord in pediatric multiple sclerosis: a preliminary study

    Energy Technology Data Exchange (ETDEWEB)

    Verhey, Leonard H. [Hospital for Sick Children, Neuroscience and Mental Health, Toronto, ON (Canada); University of Toronto, Institute of Medical Science, Faculty of Medicine, Toronto, ON (Canada); Branson, Helen M.; Shroff, Manohar [Hospital for Sick Children, Department of Diagnostic Imaging (Neuroradiology), Toronto, ON (Canada); University of Toronto, Department of Medical Imaging, Toronto, ON (Canada); Makhija, Monica [Hospital for Sick Children, Neuroscience and Mental Health, Toronto, ON (Canada); Banwell, Brenda [Hospital for Sick Children, Neuroscience and Mental Health, Toronto, ON (Canada); University of Toronto, Institute of Medical Science, Faculty of Medicine, Toronto, ON (Canada); University of Toronto, Department of Pediatrics (Neurology), Toronto, ON (Canada)

    2010-12-15

    Spinal cord lesions in adults with multiple sclerosis (MS) are thought to contribute to disability. The magnetic resonance imaging (MRI) appearance and clinical correlates of spinal cord lesions in children with MS have not been reported. T1-weighted pre- and post-gadolinium and T2-weighted TSE/FSE spine MR images of 36 children (age, 14.3 {+-} 3.3) with relapsing-remitting MS (annualized relapse rate, 0.7; disease duration, 7.5 {+-} 3.3 years) were analyzed for total lesion count, lesion location and length, intramedullary extent, and gadolinium enhancement. Clinical, demographic, laboratory, and MRI data were correlated. Lesions preferentially involved the cervical region, were predominantly focal, and involved only a portion of the transverse cord diameter. However, ten of 36 patients demonstrated longitudinally extensive lesions. Children with the highest clinical relapse rate also tended to have more spinal cord lesions and were more likely to accrue new lesions on serial spinal scans. These preliminary data suggest that MS lesions of the spinal cord in children are radiographically similar to that of adult-onset MS - supporting a common biology of pediatric- and adult-onset disease. However, children with relapsing-remitting MS can also develop longitudinally extensive lesions, suggesting that such lesions may be less specific for diseases such as neuromyelitis optica in pediatric patients. All patients recovered well from spinal cord attacks, and the presence of spinal cord lesions in the first few years of disease did not correlate with physical disability. Measures of spinal cord atrophy and longer periods of observation are required to determine the impact of spinal cord involvement in pediatric-onset MS. (orig.)

  3. MR IMAGING OF CORONARY ARTERY BYPASS GRAFT:A PRELIMINARY STUDY

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Objective. To make a preliminary investigation of the patency and function of coronary artery bypass grafts(CABG) by magnetic resonance(MR) images and to establish a suitable method for follow-up study after CABG operation among Chinese.Methods. MR imaging was performed with a Toshiba 1.5-T unit in 27 patients with 74 grafts. All patients were examined with a breath-hold ECG-gated two-dimensional fast field echo (FFE) sequence to evaluate the patency of bypass grafts, among them 16 patients with 42 grafts were further examined with a phase shift magnetic resonance angiography flow (PSMRAflow) sequence to evaluate the grafts patency as well as the flow velocity and flow volume vs. time.Results. The results showed that 66 of the 74 grafts in the patients of the present series studied with FFE were patent with a patency rate of 89.2%. The results evaluated both with FFE and PSMRAflow remained the same except that two grafts were patent with FFE and the results with PSMRAflow were uncertain. Diastolic perfusion pattern curves were found in 25 of the 32 grafts in patients of the present series. Comparing the flow curves of the grafted left internal mammary artery with those of the native right internal mammary artery in 7 patients, the systolic peak velocity value(SPV) of the grafted arteries was significantly lower than that of the ungrafted ones, whereas the diastolic peak velocity value(DPV) and the ratio of DPV to SPV were significantly greater than that of the ungrafed ones.Conclusion. The FFE and PSMRAflow sequences were efficient in evaluating patency and obtaining the curves of flow velocity and volume of the bypass grafts. Therefore, they may offer a non-invasive screening method for follow-up study in patients after CABG surgery, although its accuracy should be further evaluated in more patients and comparatively studied with other methods.

  4. Preliminary experience with drug-coated balloon angioplasty in primary percutaneous coronary intervention

    Institute of Scientific and Technical Information of China (English)

    Hee; Hwa; Ho; Julian; Tan; Yau; Wei; Ooi; Kwok; Kong; Loh; Than; Htike; Aung; Nwe; Tun; Yin; Dasdo; Antonius; Sinaga; Fahim; Haider; Jafary; Paul; Jau; Lueng; Ong

    2015-01-01

    We evaluated the clinical feasibility of using drugcoated balloon(DCB) angioplasty in patients undergoingprimary percutaneous coronary intervention(PPCI). Between January 2010 to September 2014,89 STelevation myocardial infarction patients(83% male,mean age 59 ± 14 years) with a total of 89 coronary lesions were treated with DCB during PPCI. Clinical outcomes are reported at 30 d follow-up. Left anterior descending artery was the most common target vessel for PCI(37%). Twenty-eight percent of the patients had underlying diabetes mellitus. Mean left ventricular ejection fraction was 44% ± 11%. DCB-only PCI was the predominant approach(96%) with the remaining 4% of patients receiving bail-out stenting. Thrombolysis in Myocardial Infarction(TIMI) 3 flow was successfully restored in 98% of patients. An average of 1.2 ± 0.5 DCB were used per patient,with mean DCB diameter of 2.6 ± 0.5 mm and average length of 23.2 ± 10.2 mm. At 30-d follow-up,there were 4 deaths(4.5%). No patients experienced abrupt closure of the infarctrelated artery and there was no reported target-lesion failure. Our preliminary experience showed that DCB angioplasty in PPCI was feasible and associated with a high rate of TIMI 3 flow and low 30-d ischaemic event.

  5. An overview of the Tokamak Physics Experiment vacuum vessel preliminary design

    Energy Technology Data Exchange (ETDEWEB)

    Rocco, R.E. [Raytheon Engineers and Constructors, Inc., Princeton, NJ (United States)

    1995-12-31

    The mission of the Tokamak Physics Experiment (TPX) Project is to develop the scientific basis for a compact and continuously operating tokamak fusion reactor. The vacuum vessel, which consists of a double walled torus, ports and supports, is a major element of the TPX machine. This paper provides an overview of the vacuum vessel preliminary design work. The design of the vacuum vessel is being carried out by an industrial team under subcontract to the Princeton Plasma Physics Laboratory. The respective work scopes of this team are discussed. The role of concurrent engineering is presented in the context of this design-build subcontract. A discussion of the engineering requirements, material selection rationale and vacuum vessel configuration is provided. Titanium 6Al-4V will be used to fabricate the vacuum vessel. Significant material concerns were identified with the use of titanium; hydrogen embrittlement and the effects of borated water were the major issues. A research and development (R and D) program was established to resolve these material issues as well as to develop the vessel weld details. A comprehensive analytical effort was established to perform the structural and thermal analysis of the vessel. Design details of the vessel, supports, ports, and flanges are presented.

  6. Pool film boiling experiments on a wire in low gravity: preliminary results.

    Science.gov (United States)

    Di Marco, P; Grassi, W; Trentavizi, F

    2002-10-01

    This paper reports preliminary results for pool film boiling on a wire immersed in almost saturated FC72 recently obtained during an experimental campaign performed in low gravity on the European Space Agency Zero-G airplane, (reduced gravity level 10(-2)). This is part of a long-term research program on the effect of gravitational and electric forces on boiling. The reported data set refers to experiments performed under the following conditions: (1) Earth gravity without electric field, (2) Earth gravity with electric field, (3) low gravity without electric field, and (4) low gravity with electric field. Although a decrease of gravity causes a heat transfer degradation, the electric field markedly improves heat exchange. This improvement is so effective that, beyond a certain field value, the heat flux is no longer sensitive to gravity. Two main film boiling regimes have been identified, both in normal and in low gravity: one is affected by the electric field and the other is practically insensitive to the field influence.

  7. Electromagnetic experiment to map in situ water in heated welded tuff: Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Ramirez, A.L.; Daily, W.D.

    1987-03-16

    An experiment was conducted in Tunnel Complex G at the Nevada Test Site to evaluate geotomography as a possible candidate for in situ monitoring of hydrology in the near field of a heater placed in densely welded tuff. Alterant tomographs of 200 MHz electromagnetic permittivity were made for a vertical and a horizontal plane. After the 1 kilowatt heater was turned on, the tomographs indicated a rapid and strong drying adjacent to the heater. Moisture loss was not symmetric about the heater, but seemed to be strongly influenced by heterogeneity in the rock mass. The linear character of many tomographic features and their spatial correlation with fractures mapped in boreholes are evidence that drying was most rapid along some fractures. When the heater was turned off, an increase in moisture content occurred around the heater and along the dry fractures. However, this process is much slower and the magnitude of the moisture increase much smaller than the changes observed during heating of the rock. The interpretation of the tomographs is preliminary until they can be processed without the restrictive assumption of straight ray paths for the signals through the highly heterogeneous rock mass. 15 refs., 4 figs.

  8. Preliminary experience with laparoscopic repair of associated inguinal and umbilical hernias in children.

    Science.gov (United States)

    Bertozzi, M; Magrini, E; Appignani, A

    2015-08-01

    The authors report their preliminary experience in laparoscopic repair of associated inguinal and umbilical hernias in children. Twenty-six patients affected by the association of inguinal and umbilical hernia with an umbilical defect larger than 5 mm underwent a laparoscopic procedure. A 5-mm trocar was placed through the umbilical defect for the optic. To fix the trocar to avoid loss of carboperitoneum, we fashioned and tightened a purse-string non-absorbable suture with a sliding knot around the defect. In this manner, we ensured the trocar, fixing it and avoiding any loss of CO2, proceeding safely to the laparoscopic IH repair, by means of two additional 3 mm operative trocars. At the end of the inguinal herniorrhaphy, the previously fashioned purse-string suture was tightened to repair the umbilical defect. The mean operative time for the repair of associated inguinal and umbilical hernias was 30.1 ± 7.4 min in cases of unilateral inguinal hernia and 39.5 ± 10.6 for bilateral inguinal hernia. Follow-up ranged from 8 to 32 months. Neither intra- nor post-operative complications nor recurrences were seen. This small sample suggests that this simple method is safe, effective and might be useful for pediatric surgeons performing laparoscopic repair for inguinal hernia in presence of an associated UH with a statistically significant decrease of operative time.

  9. Preliminary Λ ^0 arrow p + π ^- Signal for SELEX - Fermilab Experiment 781

    Science.gov (United States)

    Parkhurst, James F.; Dauwe, Loretta J.; E781 Collaboration

    1997-10-01

    SELEX (SEgmented Large X baryon spectrometer), a fixed target experiment at Fermilab, collected data from February to September 1997, using both 650 GeV/c Σ ^-/π ^-, and 550 GeV/c p/π ^+ beams. This run resulted in 2 billion triggered interactions being logged to tape. Primarily designed to study charmed baryons, E781 can also study hyperon production and decays, and the Primakoff effect. Λ ^0 has several decay modes, however it primarily decays into a p and π ^-. A neutral particle decay to two charged particles appears in the spectrometer as two oppositely charged tracks, originating downstream from the primary interaction in the target. Spectrometer magnets provide a transverse momentum kick which spreads the particle trajectories in a direction depending on the particles' charge. Particle momentum is determined from knowledge of the magnetic field and the track curvature. Assuming masses for the positive and negative tracks, the invariant mass and momentum of the initial neutral particle is calculated. A preliminary reconstruction of Λ ^0 decay, including the mass distribution, will be presented.

  10. [The lived experience of family member caring for a person affected by Alzheimer's disease: preliminary results].

    Science.gov (United States)

    Vellone, E; Micci, F; Sansoni, J; Sinapi, N; Cattel, C

    2000-01-01

    The aim of this article is to report the preliminary results from a phenomenological study on the lived experience of Alzheimer's caregivers. Eight caregivers involved in caring for two years at list were interviewed. The analysis of interviews by Giorgi's method showed a multidimensional reality synthesizable in eight spheres of themes: Illness, Patient, Caring, Caregiver's Life and Health, Coping, Spouse/Family, Others, Feelings. Illness has a great impact on the caregivers' life and causes the loss of the affected person even before his/her death. Caring is very hard and emotionally involving. Caregivers mainly complain the lack of support from the National Health System. The continuous involvement in caring produces also health problems, depression, and negative effects within the family. Others are considered as bad. The most common feelings are fear for possible accidents to the patients and remorses. Some caregivers have good coping style putting their faith in God, valuing the closeness of the family and living daily. The utility of the eight spheres of themes are discussed in order to guide the practice toward the caregivers.

  11. Universal newborn hearing screening: preliminary experience at the University Hospital of Cagliari

    Directory of Open Access Journals (Sweden)

    Giulia Pinna

    2012-10-01

    Full Text Available Bilateral congenital or acquired sensorineural hearing loss is a pathological condition affecting 1-2 children per 1,000 live births; it represents a major issue in public health because its late identification can negatively affect speech and language development. The aim of hearing screening is to obtain diagnosis and management of hearing loss as soon as possible; in fact early diagnosis and treatment allow children with congenital hearing impairment to acquire adequate linguistic competence. The present study reports our preliminary experience in newborn hearing screening at Neonatology services of University of Cagliari (Italy. During the first semester of surveillance, between January 2012 and June 2012, hearing screening was performed on a total of 901 babies using two different methods, TEOAEs in healthy neonates and automated ABR in high-risk babies. All infants were screened prior to hospital discharge; in some cases, especially for preterm infants of Neonatal Intensive Care Unit and Puericulture Institute, the screening was performed after discharge, to achieve a possible better global and acoustic maturation; 5 cases of hearing impairment were found. In the present study the Authors confirmed that it is possible to start a universal hearing screening in a relatively short time reaching the percentages suggested by Joint Committee on Infant Hearing.

  12. Preliminary test of an imaging probe for nuclear medicine using hybrid pixel detectors

    CERN Document Server

    Bertolucci, Ennio; Mettivier, G; Montesi, M C; Russo, P

    2002-01-01

    We are investigating the feasibility of an intraoperative imaging probe for lymphoscintigraphy with Tc-99m tracer, for sentinel node radioguided surgery, using the Medipix series of hybrid detectors coupled to a collimator. These detectors are pixelated semiconductor detectors bump-bonded to the Medipix1 photon counting read-out chip (64x64 pixel, 170 mu m pitch) or to the Medipix2 chip (256x256 pixel, 55 mu m pitch), developed by the European Medipix collaboration. The pixel detector we plan to use in the final version of the probe is a semi-insulating GaAs detector or a 1-2 mm thick CdZnTe detector. For the preliminary tests presented here, we used 300-mu m thick silicon detectors, hybridized via bump-bonding to the Medipix1 chip. We used a tungsten parallel-hole collimator (7 mm thick, matrix array of 64x64 100 mu m circular holes with 170 mu m pitch), and a 22, 60 and 122 keV point-like (1 mm diameter) radioactive sources, placed at various distances from the detector. These tests were conducted in order ...

  13. Biological image construction by using Raman radiation and Pca: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Martinez E, J. C. [IPN, Unidad Profesional Interdisciplinaria de Ingenieria, Campus Guanajuato, Av. Mineral de Valenciana 200, Col. Fracc. Industrial Puerto Interior, 36275 Silao, Guanajuato (Mexico); Cordova F, T. [Universidad de Guanajuato, DIC, Departamento de Ingenieria Fisica, Loma del Bosque No. 103, Col. Lomas del Campestre, 37150 Leon, Guanajuato (Mexico); Hugo R, V., E-mail: jcmartineze@ipn.mx [Universidad de Guadalajara, Centro Universitario de Tonala, Morelos No. 180, 69584 Tonala, Jalisco (Mexico)

    2015-10-15

    Full text: In the last years, the Raman spectroscopy (Rs) technique has had some applications in the study and analysis of biological samples, due to it is able to detect concentrations or presence of certain organic and inorganic compounds of medical interest. In this work, raw data were obtained through measurements in selected points on a square regions in order to detect specific organic / inorganic compounds on biological samples. Gold nano stars samples were prepared and coated with membrane markers (CD 10+ and CD 19+) and diluted in leukemic B lymphocytes. Each data block was evaluated independently by the method of principal component analysis (Pca) in order to find representative dimensionless values (Cp) for each Raman spectrum in a specific coordinate. Each Cp was normalized in a range of 0-255 in order to generate a representative image of 8 bits of the region under study. Data acquisition was performed with Raman microscopy system Renishaw in Via in the range of 550 to 1700 cm-1 with a 785 nm laser source, with a power of 17 m W and 15 s of exposure time were used for each spectrum. In preliminary results could detect the presence of molecular markers CD 10+ and CD 19+ with gold nano stars and discrimination between both markers. The results suggest conducting studies with specific concentrations organic and inorganic materials. (Author)

  14. The Habitable Exoplanet (HabEx) Imaging Mission: preliminary science drivers and technical requirements

    Science.gov (United States)

    Mennesson, Bertrand; Gaudi, Scott; Seager, Sara; Cahoy, Kerri; Domagal-Goldman, Shawn; Feinberg, Lee; Guyon, Olivier; Kasdin, Jeremy; Marois, Christian; Mawet, Dimitri; Tamura, Motohide; Mouillet, David; Prusti, Timo; Quirrenbach, Andreas; Robinson, Tyler; Rogers, Leslie; Scowen, Paul; Somerville, Rachel; Stapelfeldt, Karl; Stern, Daniel; Still, Martin; Turnbull, Margaret; Booth, Jeffrey; Kiessling, Alina; Kuan, Gary; Warfield, Keith

    2016-07-01

    HabEx is one of four candidate flagship missions being studied in detail by NASA, to be submitted for consideration to the 2020 Decadal Survey in Astronomy and Astrophysics for possible launch in the 2030s. It will be optimized for direct imaging and spectroscopy of potentially habitable exoplanets, and will also enable a wide range of general astrophysics science. HabEx aims to fully characterize planetary systems around nearby solar-type stars for the first time, including rocky planets, possible water worlds, gas giants, ice giants, and faint circumstellar debris disks. In particular, it will explore our nearest neighbors and search for signs of habitability and biosignatures in the atmospheres of rocky planets in the habitable zones of their parent stars. Such high spatial resolution, high contrast observations require a large (roughly greater than 3.5m), stable, and diffraction-limited optical space telescope. Such a telescope also opens up unique capabilities for studying the formation and evolution of stars and galaxies. We present some preliminary science objectives identified for HabEx by our Science and Technology Definition Team (STDT), together with a first look at the key challenges and design trades ahead.

  15. The Habitable Exoplanet (HabEx) Imaging Mission: Preliminary Science Drivers and Technical Requirements

    Science.gov (United States)

    Gaudi, B. Scott; Habitable Exoplanet Imaging Mission Science and Technology Definition Team

    2017-01-01

    HabEx is one of four candidate flagship missions being studied in detail by NASA, to be submitted for consideration to the 2020 Decadal Survey in Astronomy and Astrophysics for possible launch in the 2030s. It will be optimized for direct imaging and spectroscopy of potentially habitable exoplanets, and will also enable a wide range of general astrophysics science. HabEx aims to fully characterize planetary systems around nearby solar-type stars for the first time, including rocky planets, possible water worlds, gas giants, ice giants, and faint circumstellar debris disks. In particular, it will explore our nearest neighbors and search for signs of habitability and biosignatures in the atmospheres of rocky planets in the habitable zones of their parent stars. Such high spatial resolution, high contrast observations require a large (roughly greater than 3.5m), stable, and diffraction-limited optical space telescope. Such a telescope also opens up unique capabilities for studying the formation and evolution of stars and galaxies. We present some preliminary science objectives identified for HabEx by our Science and Technology Definition Team (STDT), together with a first look at the key challenges and design trades ahead.

  16. PET/MR imaging of atherosclerosis: initial experience and outlook.

    Science.gov (United States)

    Rischpler, Christoph; Nekolla, Stephan G; Beer, Ambros J

    2013-01-01

    Hybrid scanners such as PET/CT have in the past emerged as a valuable modality in clinical routine as well as an important research tool. Recently, the newly developed fully integrated PET/MR scanners were introduced to the market, raising high expectations especially due to the excellent soft tissue contrast and functional imaging capabilities of MRI. In this issue of the American Journal of Nuclear Medicine and Molecular Imaging, initial experiences using a hybrid PET/MR scanner for carotid artery imaging in a group of patients with increased risk for atherosclerosis are described. This represents a proof-of-principle study, which could stimulate future applications of this powerful modality in atherosclerotic plaque imaging.

  17. IDEAL: Images Across Domains, Experiments, Algorithms and Learning

    Science.gov (United States)

    Ushizima, Daniela M.; Bale, Hrishikesh A.; Bethel, E. Wes; Ercius, Peter; Helms, Brett A.; Krishnan, Harinarayan; Grinberg, Lea T.; Haranczyk, Maciej; Macdowell, Alastair A.; Odziomek, Katarzyna; Parkinson, Dilworth Y.; Perciano, Talita; Ritchie, Robert O.; Yang, Chao

    2016-09-01

    Research across science domains is increasingly reliant on image-centric data. Software tools are in high demand to uncover relevant, but hidden, information in digital images, such as those coming from faster next generation high-throughput imaging platforms. The challenge is to analyze the data torrent generated by the advanced instruments efficiently, and provide insights such as measurements for decision-making. In this paper, we overview work performed by an interdisciplinary team of computational and materials scientists, aimed at designing software applications and coordinating research efforts connecting (1) emerging algorithms for dealing with large and complex datasets; (2) data analysis methods with emphasis in pattern recognition and machine learning; and (3) advances in evolving computer architectures. Engineering tools around these efforts accelerate the analyses of image-based recordings, improve reusability and reproducibility, scale scientific procedures by reducing time between experiments, increase efficiency, and open opportunities for more users of the imaging facilities. This paper describes our algorithms and software tools, showing results across image scales, demonstrating how our framework plays a role in improving image understanding for quality control of existent materials and discovery of new compounds.

  18. IDEAL: Images Across Domains, Experiments, Algorithms and Learning

    Science.gov (United States)

    Ushizima, Daniela M.; Bale, Hrishikesh A.; Bethel, E. Wes; Ercius, Peter; Helms, Brett A.; Krishnan, Harinarayan; Grinberg, Lea T.; Haranczyk, Maciej; Macdowell, Alastair A.; Odziomek, Katarzyna; Parkinson, Dilworth Y.; Perciano, Talita; Ritchie, Robert O.; Yang, Chao

    2016-11-01

    Research across science domains is increasingly reliant on image-centric data. Software tools are in high demand to uncover relevant, but hidden, information in digital images, such as those coming from faster next generation high-throughput imaging platforms. The challenge is to analyze the data torrent generated by the advanced instruments efficiently, and provide insights such as measurements for decision-making. In this paper, we overview work performed by an interdisciplinary team of computational and materials scientists, aimed at designing software applications and coordinating research efforts connecting (1) emerging algorithms for dealing with large and complex datasets; (2) data analysis methods with emphasis in pattern recognition and machine learning; and (3) advances in evolving computer architectures. Engineering tools around these efforts accelerate the analyses of image-based recordings, improve reusability and reproducibility, scale scientific procedures by reducing time between experiments, increase efficiency, and open opportunities for more users of the imaging facilities. This paper describes our algorithms and software tools, showing results across image scales, demonstrating how our framework plays a role in improving image understanding for quality control of existent materials and discovery of new compounds.

  19. Wageningen Urban Rainfall Experiment 2014 (WURex14): Experimental setup and preliminary results

    Science.gov (United States)

    van Leth, Thomas C.; Uijlenhoet, Remko; Overeem, Aart; Leijnse, Hidde; Hazenberg, Pieter; Berne, Alexis

    2016-04-01

    Microwave links from cellular communication networks have been shown to be able to provide valuable information concerning the space-time variability of rainfall. In particular over urban areas, where network densities are generally high, they have the potential to complement existing dedicated infrastructure to measure rainfall (gauges, radars). In addition, microwave links provide a great opportunity for ground-based rainfall measurement for those land surface areas of the world where gauges and radars are generally lacking. Such information is not only crucial for water management and agriculture, but also for instance for ground validation of space-borne rainfall estimates such as those provided by the GPM (Global Precipitation Measurement) mission. WURex14 is dedicated to address several errors and uncertainties associated with such quantitative precipitation estimates in detail. The core of the experiment is provided by three co-located microwave links installed between two major buildings on the Wageningen University campus, approximately 2 km apart: a 38 GHz commercial microwave link, provided by T-Mobile NL, and 26 GHz and 38 GHz (dual-polarization) research microwave links from RAL. Transmitting and receiving antennas have been attached to masts installed on the roofs of the two buildings, about 30 m above the ground. This setup has been complemented with a Scintec infrared Large-Aperture Scintillometer, installed over the same path, as well as 5 Parsivel optical disdrometers and an automated rain gauge positioned at several locations along the path. Temporal sampling of the received signals was performed at a rate of 20 Hz. The setup is being monitored by time-lapse cameras to assess the state of the antennas as well as the atmosphere. Finally, data is available from the KNMI weather radars and an automated weather station situated just outside Wageningen. The experiment has been active between August 2014 and December 2015. We give a global overview of

  20. Evaluation of chemotherapy response in ovarian cancer treatment using quantitative CT image biomarkers: a preliminary study

    Science.gov (United States)

    Qiu, Yuchen; Tan, Maxine; McMeekin, Scott; Thai, Theresa; Moore, Kathleen; Ding, Kai; Liu, Hong; Zheng, Bin

    2015-03-01

    The purpose of this study is to identify and apply quantitative image biomarkers for early prediction of the tumor response to the chemotherapy among the ovarian cancer patients participated in the clinical trials of testing new drugs. In the experiment, we retrospectively selected 30 cases from the patients who participated in Phase I clinical trials of new drug or drug agents for ovarian cancer treatment. Each case is composed of two sets of CT images acquired pre- and post-treatment (4-6 weeks after starting treatment). A computer-aided detection (CAD) scheme was developed to extract and analyze the quantitative image features of the metastatic tumors previously tracked by the radiologists using the standard Response Evaluation Criteria in Solid Tumors (RECIST) guideline. The CAD scheme first segmented 3-D tumor volumes from the background using a hybrid tumor segmentation scheme. Then, for each segmented tumor, CAD computed three quantitative image features including the change of tumor volume, tumor CT number (density) and density variance. The feature changes were calculated between the matched tumors tracked on the CT images acquired pre- and post-treatments. Finally, CAD predicted patient's 6-month progression-free survival (PFS) using a decision-tree based classifier. The performance of the CAD scheme was compared with the RECIST category. The result shows that the CAD scheme achieved a prediction accuracy of 76.7% (23/30 cases) with a Kappa coefficient of 0.493, which is significantly higher than the performance of RECIST prediction with a prediction accuracy and Kappa coefficient of 60% (17/30) and 0.062, respectively. This study demonstrated the feasibility of analyzing quantitative image features to improve the early predicting accuracy of the tumor response to the new testing drugs or therapeutic methods for the ovarian cancer patients.

  1. Preliminary Results on Different Impedance Contrast Agents for Pulmonary Perfusion Imaging with Electrical Impedance Tomography

    Science.gov (United States)

    Nguyen, D. T.; Kosobrodov, R.; Barry, M. A.; Chik, W.; Pouliopoulos, J.; Oh, T. I.; Thiagalingam, A.; McEwan, A.

    2013-04-01

    Recent studies in animal models suggest that the use of small volume boluses of NaCl as an impedance contrast agent can significantly improve pulmonary perfusion imaging by Electrical Impedance Tomography (EIT). However, these studies used highly concentrated NaCl solution (20%) which may have adverse effects on the patients. In a pilot experiment, we address this problem by comparing a number of different Impedance Contrast Boluses (ICBs). Conductivity changes in the lungs of a sheep after the injection of four different ICBs were compared, including three NaCl-based ICBs and one glucose-based ICB. The following procedure was followed for each ICB. Firstly, ventilation was turned off to provide an apneic window of approximately 40s to image the conductivity changes due to the ICB. Each ICB was then injected through a pig-tail catheter directly into the right atrium. EIT images were acquired throughout the apnea to capture the conductivity change. For each ICB, the experiment was repeated three times. The three NaCl-based ICB exhibited similar behaviour in which following the injection of each of these ICBs, the conductivity of each lung predictably increased. The effect of the ICB of 5% glucose solution was inconclusive. A small decrease in conductivity in the left lung was observed in two out of three cases and none was discernible in the right lung.

  2. Preliminary results on in-vivo imaging of upper airway inhalation injuries using anatomical optical coherence tomography

    Science.gov (United States)

    Phan, Anthony; Karnowski, Karol; Lee, Qingyun; Fejes, Peter; Quirk, Bryden; McLaughlin, Robert; Wood, Fiona M.; Sampson, David D.

    2017-04-01

    Quantitative assessment of upper airway geometry using optical coherence tomography in burns patients could provide physicians with the information needed to make critical decisions. We have developed a high speed catheter based OCT system capable of real time imaging in airways up to 3cm in diameter. Preliminary scans of inhalation injured airways are presented to demonstrate the feasibility of aOCT as a diagnostic tool for assessing burns patients.

  3. First Human Experience with Directly Image-able Iodinated Embolization Microbeads.

    Science.gov (United States)

    Levy, Elliot B; Krishnasamy, Venkatesh P; Lewis, Andrew L; Willis, Sean; Macfarlane, Chelsea; Anderson, Victoria; van der Bom, Imramsjah Mj; Radaelli, Alessandro; Dreher, Matthew R; Sharma, Karun V; Negussie, Ayele; Mikhail, Andrew S; Geschwind, Jean-Francois H; Wood, Bradford J

    2016-08-01

    To describe first clinical experience with a directly image-able, inherently radio-opaque microspherical embolic agent for transarterial embolization of liver tumors. LC Bead LUMI™ is a new product based upon sulfonate-modified polyvinyl alcohol hydrogel microbeads with covalently bound iodine (~260 mg I/ml). 70-150 μ LC Bead LUMI™ iodinated microbeads were injected selectively via a 2.8 Fr microcatheter to near complete flow stasis into hepatic arteries in three patients with hepatocellular carcinoma, carcinoid, or neuroendocrine tumor. A custom imaging platform tuned for LC LUMI™ microbead conspicuity using a cone beam CT (CBCT)/angiographic C-arm system (Allura Clarity FD20, Philips) was used along with CBCT embolization treatment planning software (EmboGuide, Philips). LC Bead LUMI™ image-able microbeads were easily delivered and monitored during the procedure using fluoroscopy, single-shot radiography (SSD), digital subtraction angiography (DSA), dual-phase enhanced and unenhanced CBCT, and unenhanced conventional CT obtained 48 h after the procedure. Intra-procedural imaging demonstrated tumor at risk for potential under-treatment, defined as paucity of image-able microbeads within a portion of the tumor which was confirmed at 48 h CT imaging. Fusion of pre- and post-embolization CBCT identified vessels without beads that corresponded to enhancing tumor tissue in the same location on follow-up imaging (48 h post). LC Bead LUMI™ image-able microbeads provide real-time feedback and geographic localization of treatment in real time during treatment. The distribution and density of image-able beads within a tumor need further evaluation as an additional endpoint for embolization.

  4. Relaxation enhanced compressed sensing three-dimensional black-blood vessel wall MR imaging: Preliminary studies.

    Science.gov (United States)

    Li, Bo; Li, Hao; Li, Jun; Zhang, Yuchen; Wang, Xiaoying; Zhang, Jue; Dong, Li; Fang, Jing

    2015-09-01

    In this study, we sought to investigate the feasibility of a new technique termed relaxation enhanced compressed sensing three-dimensional motion-sensitizing driven equilibrium prepared 3D rapid gradient echo sequence (RECS-3D MERGE). The RECS-3D MERGE sequence consisted of a 3D MERGE sequence for imaging, a period of delay time (TD) for relaxation enhancement, and a pseudo-centric phase encoding order used for under-sampling acquisition to maintain scan efficiency. Seven healthy volunteers and six patients with 40% to 75% carotid artery stenosis were recruited in this study. Healthy subjects underwent 3D MERGE, RECS-3D MERGE and two-dimensional (2D) T1-weighted double inversion recovery fast spin echo (T1W DIR-FSE) scans. The signal ratio (SR) values of 21 RECS-3D MERGE scans were compared in order to determine the optimal scan parameter set of acceleration factor (AF) and delay time (TD) for RECS-3D MERGE sequence. Patients then underwent 3D MERGE, RECS-3D MERGE using the aforementioned optimal scan parameter set and 2D T1W DIR-FSE scans. Two radiologists, blinded to the imaging technique, qualitatively graded each image on a six-point ordinal scale. The highest value of SR occurred with the scan parameter set of 3-fold AF and 800ms TD. Compared to 3D MERGE, RECS-3D MERGE with the parameter set significantly improved the image quality for both healthy subjects and patients experiments, while the scan efficiency was not sacrificed. And no significant differences were observed in the subjective scores of RECS-3D MERGE and 2D T1W DIR-FSE image qualities. RECS-3D MERGE technique achieved significant improvement in black-blood image quality compared with 3D MERGE. And the image quality of this 3D rapid carotid black-blood imaging technique is comparable to 2D T1W DIR-FSE while it has much higher scan efficiency. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Accuracy Considerations in Image-guided Cardiac Interventions: Experience and Lessons Learned

    Science.gov (United States)

    Linte, Cristian A.; Lang, Pencilla; Rettmann, Maryam E.; Cho, Daniel S.; Holmes, David R.; Robb, Richard A.; Peters, Terry M.

    2014-01-01

    Motivation Medical imaging and its application in interventional guidance has revolutionized the development of minimally invasive surgical procedures leading to reduced patient trauma, fewer risks, and shorter recovery times. However, a frequently posed question with regards to an image guidance system is “how accurate is it?” On one hand, the accuracy challenge can be posed in terms of the tolerable clinical error associated with the procedure; on the other hand, accuracy is bound by the limitations of the system’s components, including modeling, patient registration, and surgical instrument tracking, all of which ultimately impact the overall targeting capabilities of the system. Methods While these processes are not unique to any interventional specialty, this paper discusses them in the context of two different cardiac image-guidance platforms: a model-enhanced ultrasound platform for intracardiac interventions and a prototype system for advanced visualization in image-guided cardiac ablation therapy. Results Pre-operative modeling techniques involving manual, semi-automatic and registration-based segmentation are discussed. The performance and limitations of clinically feasible approaches for patient registration evaluated both in the laboratory and operating room are presented. Our experience with two different magnetic tracking systems for instrument and ultrasound transducer localization is reported. Ultimately, the overall accuracy of the systems is discussed based on both in vitro and preliminary in vivo experience. Conclusion While clinical accuracy is specific to a particular patient and procedure and vastly dependent on the surgeon’s experience, the system’s engineering limitations are critical to determine whether the clinical requirements can be met. PMID:21671097

  6. Magnetic Field Gradient Calibration as an Experiment to Illustrate Magnetic Resonance Imaging

    Science.gov (United States)

    Seedhouse, Steven J.; Hoffmann, Markus M.

    2008-01-01

    A nuclear magnetic resonance (NMR) spectroscopy experiment for the undergraduate physical chemistry laboratory is described that encompasses both qualitative and quantitative pedagogical goals. Qualitatively, the experiment illustrates how images are obtained in magnetic resonance imaging (MRI). Quantitatively, students experience the…

  7. Preliminary stress characterization for an in-situ stimulation experiment at the Grimsel Underground Laboratory

    Science.gov (United States)

    Krietsch, Hannes; Doetsch, Joseph; Gischig, Valentin; Amann, Florian; Jalali, Mohammadreza; Madonna, Claudio; Evans, Keith; Valley, Benoit; Giardini, Domenico; Wiemer, Stefan; Maurer, Hansruedi; Loew, Simon

    2016-04-01

    A decameter-scale in-situ stimulation experiment is currently being executed at the Grimsel Test Site in Switzerland, spanning from hydraulic fracturing to controlled fault-slip experiments. For the feasibility of this project the in-situ stress tensor is of foremost importance. Therefore a unique stress characterization campaign combining stress relief methods (overcoring of USBM and CSIRO-HI probes) with hydraulic fracturing (HF) and hydraulic testing on pre-existing fractures (HTPF) in three boreholes was conducted in a first phase of this project. During all hydraulic stress measurements, micro-seismicity was monitored and localized in real time utilizing a dense network of piezo-electric sensors. In this contribution, we present preliminary results of the stress characterization and compare the derived stress tensor with previous estimates of the stress state. The stress characterization campaign was conducted in three boreholes, one sub-vertical and two sub-horizontal boreholes, assuming that the sub-vertical and one sub-horizontal are parallel to a principal stress component. A major task in this contribution is the integration of the different stress characterization methods. Our results of the different methods (overcoring and HF) are largely consistent, but disagree with some of the previous stress orientation estimates. From the new campaign the overcoring measurements indicate a sub-horizontal sigma1 of 17.3 MPa with a strike of 145°, a sigma2 of 9.7 MPa with 241°/69° and a sigma3 of 8.3 MPa with 055°/21° using an isotropic approach for inversion calculation. Whereas the USBM-Probe measures a projection of the principal stresses in a plane normal to borehole axis, the CSIRO-HI Probe provides the real 3D stress tensor. The HF and HTPF measurements indicate a far-field minimum horizontal stress between 8.7 and 9.1 MPa, consistent with the overcoring. Principal stresses, estimated by location of micro-seismic events during HF and HTPF, suggest that

  8. Preliminary studies of fluorescence image-guided photothermal therapy of human oesophageal adenocarcinoma in vivo using multifunctional gold nanorods

    Science.gov (United States)

    Nabavi, Elham; Singh, Mohan; Zhou, Yu; Gallina, Maria Elena; Zhao, Hailin; Ma, Daqing; Cass, Anthony; Hanna, George; Elson, Daniel S.

    2016-03-01

    We present a preliminary in vivo study of fluorescence imaging and photothermal therapy (PTT) of human oesophageal adenocarcinoma using multi-functionalised gold nanorods (GNRs). After establishing tumour xenograft in mouse functionalised GNRs were administrated intravenously (IV). Fluorescence imaging was performed to detect the tumour area. The intensity of the fluorescence signal varied significantly across the tumour site and surrounding tissues. PTT was then performed using a 808 nm continuous wave diode laser to irradiate the tumour for 3 minutes, inducing a temperature rise of ~44°C, which photothermally ablated the tumour.

  9. Images of Poverty in Contemporary Realistic Fiction for Youth: Preliminary Results of a Content Analysis Using a Social Psychological Conceptual Framework.

    Science.gov (United States)

    Fitzgibbons, Shirley A.; Tilley, Carol L.

    This preliminary study of 20 contemporary realistic fiction books for youth, in middle school and above, analyzed images of poverty using a framework adapted from the work of Robert Leahy. Findings are related to demographics, images of poverty and emerging themes. Results indicate that, as a whole, the sample of books rely on concrete images of…

  10. Cardiac biplane strain imaging: initial in vivo experience

    Energy Technology Data Exchange (ETDEWEB)

    Lopata, R G P; Nillesen, M M; Thijssen, J M; De Korte, C L [Clinical Physics Laboratory, Radboud University Nijmegen Medical Centre, Nijmegen (Netherlands); Verrijp, C N; Lammens, M M Y; Van der Laak, J A W M [Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen (Netherlands); Singh, S K; Van Wetten, H B [Department of Cardiothoracic Surgery, Radboud University Nijmegen Medical Centre, Nijmegen (Netherlands); Kapusta, L [Pediatric Cardiology, Department of Pediatrics, Radboud University Nijmegen Medical Centre, Nijmegen (Netherlands)], E-mail: R.Lopata@cukz.umcn.nl

    2010-02-21

    In this study, first we propose a biplane strain imaging method using a commercial ultrasound system, yielding estimation of the strain in three orthogonal directions. Secondly, an animal model of a child's heart was introduced that is suitable to simulate congenital heart disease and was used to test the method in vivo. The proposed approach can serve as a framework to monitor the development of cardiac hypertrophy and fibrosis. A 2D strain estimation technique using radio frequency (RF) ultrasound data was applied. Biplane image acquisition was performed at a relatively low frame rate (<100 Hz) using a commercial platform with an RF interface. For testing the method in vivo, biplane image sequences of the heart were recorded during the cardiac cycle in four dogs with an aortic stenosis. Initial results reveal the feasibility of measuring large radial, circumferential and longitudinal cumulative strain (up to 70%) at a frame rate of 100 Hz. Mean radial strain curves of a manually segmented region-of-interest in the infero-lateral wall show excellent correlation between the measured strain curves acquired in two perpendicular planes. Furthermore, the results show the feasibility and reproducibility of assessing radial, circumferential and longitudinal strains simultaneously. In this preliminary study, three beagles developed an elevated pressure gradient over the aortic valve ({delta}p: 100-200 mmHg) and myocardial hypertrophy. One dog did not develop any sign of hypertrophy ({delta}p = 20 mmHg). Initial strain (rate) results showed that the maximum strain (rate) decreased with increasing valvular stenosis (-50%), which is in accordance with previous studies. Histological findings corroborated these results and showed an increase in fibrotic tissue for the hearts with larger pressure gradients (100, 200 mmHg), as well as lower strain and strain rate values.

  11. Preliminary Results of the NASA Beacon Receiver for Alphasat Aldo Paraboni TDP5 Propagation Experiment

    Science.gov (United States)

    Nessel, James; Morse, Jacquelynne; Zemba, Michael; Riva, Carlo; Luini, Lorenzo

    2014-01-01

    NASA Glenn Research Center (GRC) and the Politecnico di Milano (POLIMI) have initiated a joint propagation campaign within the framework of the Alphasat propagation experiment to characterize rain attenuation, scintillation, and gaseous absorption effects of the atmosphere in the 40 GHz band. NASA GRC has developed and installed a K/Q-band (20/40 GHz) beacon receiver at the POLIMI campus in Milan, Italy, which receives the 20/40 GHz signals broadcast from the Alphasat Aldo Paraboni TDP#5 beacon payload. The primary goal of these measurements is to develop a physical model to improve predictions of communications systems performance within the Q-band. Herein, we describe the design and preliminary performance of the NASA propagation terminal, which has been installed and operating in Milan since May 2014. The receiver is based upon a validated Fast Fourier Transform (FFT) I/Q digital design approach utilized in other operational NASA propagation terminals, but has been modified to employ power measurement via a frequency estimation technique and to coherently track and measure the amplitude of the 20/40 GHz beacon signals. The system consists of a 1.2-m K-band and a 0.6-m Qband Cassegrain reflector employing synchronous open-loop tracking to track the inclined orbit of the Alphasat satellite. An 8 Hz sampling rate is implemented to characterize scintillation effects, with a 1-Hz measurement bandwidth dynamic range of 45 dB. A weather station with an optical disdrometer is also installed to characterize rain drop size distribution for correlation with physical based models.

  12. Risk of surgical site infection in paediatric herniotomies without any prophylactic antibiotics: A preliminary experience

    Directory of Open Access Journals (Sweden)

    Dhananjay Vaze

    2014-01-01

    Full Text Available Background: Different studies underline the use of pre-operative antibiotic prophylaxis in clean surgeries like herniotomy and inguinal orchiopexy. But, the meta-analyses do not recommend nor discard the use of prophylactic pre-operative antibiotics. The scarcity of controlled clinical trials in paediatric population further vitiates the matter. This study assessed the difference in the rate of early post-operative wound infection cases in children who received single dose of pre-operative antibiotics and children who did not receive antibiotics after inguinal herniotomy and orchiopexy. Materials and Methods: This randomised prospective study was conducted in Paediatric Surgery department of PGIMER Chandigarh. Out of 251 patients, 112 patients were randomised to the case group and 139 were ascribed to the control group. The patients in control group were given a standard regimen of single dose of intravenous antibiotic at the time of induction followed by 3-4 days of oral antibiotic. Case group patients underwent the surgical procedure in similar manner with no antibiotic either at the time of induction or post-operatively. Results: The incidence of surgical site infection in case group was 3.73 % and that in control group was 2.22%. The observed difference in the incidence of surgical site infection was statistically insignificant (P value = 0.7027. The overall infection rate in case and control group was 2.89%. Conclusions: Our preliminary experience suggests that there is no statistically significant difference in the proportion of early post-operative wound infection between the patients who received single dose of pre-operative antibiotics and the patients who received no antibiotics after inguinal herniotomy and orchiopexy. The risk of surgical site infection in paediatric heriotomies does not increase even if the child′s weight is less than his/her expected weight for age.

  13. DENOTATIVE ORIGINS OF ABSTRACT IMAGES IN LINGUISTIC EXPERIMENT

    Directory of Open Access Journals (Sweden)

    Elina, E.

    2017-03-01

    Full Text Available The article discusses the refusal from denotation (the subject, as the basic principle of abstract images, and semiotic problems arising in connection with this principle: how to solve the contradiction between the pointlessness and iconic nature of the image? Is it correct in the absence of denotation to recognize abstract representation of a single-level entity? The solution is proposed to decide these questions with the help of a psycholinguistic experiment in which the verbal interpretation of abstract images made by both experienced and “naive” audience-recipients demonstrates the objectivity of perception of denotative “traces” and the presence of denotative invariant in an abstract form.

  14. Diffusion imaging with stimulated echoes: signal models and experiment design

    CERN Document Server

    Alexander, Daniel C

    2013-01-01

    Purpose: Stimulated echo acquisition mode (STEAM) diffusion MRI can be advantageous over pulsed-gradient spin-echo (PGSE) for diffusion times that are long compared to $\\ttwo$. It is important therefore for biomedical diffusion imaging applications at 7T and above where $\\ttwo$ is short. However, imaging gradients in the STEAM sequence contribute much greater diffusion weighting than in PGSE, but are often ignored during post-processing. We demonstrate here that this can severely bias parameter estimates. Method: We present models for the STEAM signal for free and restricted diffusion that account for crusher and slice-select (butterfly) gradients to avoid such bias. The butterfly gradients also disrupt experiment design, typically by skewing gradient-vectors towards the slice direction. We propose a simple compensation to the diffusion gradient vector specified to the scanner that counterbalances the butterfly gradients to preserve the intended experiment design. Results: High-field data fixed monkey brain e...

  15. The anatomy of extended limbic pathways in Asperger syndrome: a preliminary diffusion tensor imaging tractography study.

    Science.gov (United States)

    Pugliese, Luca; Catani, Marco; Ameis, Stephanie; Dell'Acqua, Flavio; Thiebaut de Schotten, Michel; Murphy, Clodagh; Robertson, Dene; Deeley, Quinton; Daly, Eileen; Murphy, Declan G M

    2009-08-15

    It has been suggested that people with autistic spectrum disorder (ASD) have altered development (and connectivity) of limbic circuits. However, direct evidence of anatomical differences specific to white matter pathways underlying social behaviour and emotions in ASD is lacking. We used Diffusion Tensor Imaging Tractography to compare, in vivo, the microstructural integrity and age-related differences in the extended limbic pathways between subjects with Asperger syndrome and healthy controls. Twenty-four males with Asperger syndrome (mean age 23+/-12 years, age range: 9-54 years) and 42 age-matched male controls (mean age 25+/-10 years, age range: 9-54 years) were studied. We quantified tract-specific diffusivity measurements as indirect indexes of microstructural integrity (e.g. fractional anisotropy, FA; mean diffusivity, MD) and tract volume (e.g. number of streamlines) of the main limbic tracts. The dissected limbic pathways included the inferior longitudinal fasciculus, inferior frontal occipital fasciculus, uncinate, cingulum and fornix. There were no significant between-group differences in FA and MD. However, compared to healthy controls, individuals with Asperger syndrome had a significantly higher number of streamlines in the right (p=.003) and left (p=.03) cingulum, and in the right (p=.03) and left (p=.04) inferior longitudinal fasciculus. In contrast, people with Asperger syndrome had a significantly lower number of streamlines in the right uncinate (p=.02). Within each group there were significant age-related differences in MD and number of streamlines, but not FA. However, the only significant age-related between-group difference was in mean diffusivity of the left uncinate fasciculus (Z(obs)=2.05) (p=.02). Our preliminary findings suggest that people with Asperger syndrome have significant differences in the anatomy, and maturation, of some (but not all) limbic tracts.

  16. A preliminary validation study of diffusion tensor imaging as a measure of functional brain injury.

    Science.gov (United States)

    Fox, Robert J; McColl, Roderick W; Lee, Jar-Chi; Frohman, Teresa; Sakaie, Ken; Frohman, Elliot

    2008-09-01

    Diffusion tensor imaging (DTI) characterizes multiple sclerosis (MS) tissue injury, although it has remained unproven whether DTI changes in disease have functional consequences. The medial longitudinal fasciculus (MLF) is a key brainstem pathway for ocular adduction and is commonly injured in patients with MS, typically resulting in internuclear ophthalmoparesis. To validate DTI as a physiologically relevant measure of brain tissue integrity. A correlation study of ocular dysmotility and DTI conducted between January 2004 and September 2004. Multiple Sclerosis Center, University of Texas Southwestern Medical Center, Dallas. Patients Six patients with chronic, unilateral, or bilateral internuclear ophthalmoparesis and 10 healthy control subjects. Main Outcome Measure We used infrared oculography to correlate the velocity versional dysconjugacy index, defined as the ratio of the velocity of the abducting to adducting eye movements during horizontal saccades, and DTI measures within the MLF as measured through an anatomical overlay. Overall diffusion was measured by mean diffusivity, and anisotropy was measured by the lattice index. Within the pontine MLF, the mean diffusivity was increased compared with healthy controls (P r = 0.65, P r = 0.46, P = .07). Similar correlations were found between the versional dysconjugacy index and the lattice index (left: r = -0.43, P = .09; right: r = -0.65, P <.01). We identified DTI evidence of pathologic disruption of a small brainstem fiber pathway, which is crucial for accurate horizontal eye movements. In this small study, we observed correlations between the DTI changes and oculomotor dysfunction. Our preliminary observations provide criterion validity of DTI as a surrogate marker of brain tissue integrity.

  17. A sidelobe suppression method with experiment for underwater acoustic imaging

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    In this paper,a sidelobe suppression method using nonuniformly spaced array with aperture apodization processing is proposed for underwater acoustic imaging in near field,which is studied both in theory and experiment.The focused beamforming based on spherical wave propagation theory is used in the method.Firstly,the nonuniform array with low sidelobe is designed for suppressing the sidelobe of one-way beam pattern by spacing perturbation.Then, applying the aperture apodization technique to underwater ac...

  18. Dendritic iodinated contrast agents with PEG-cores for CT imaging: synthesis and preliminary characterization.

    Science.gov (United States)

    Fu, Yanjun; Nitecki, Danute E; Maltby, David; Simon, Gerhard H; Berejnoi, Kirill; Raatschen, Hans-Juergen; Yeh, Benjamin M; Shames, David M; Brasch, Robert C

    2006-01-01

    The purpose of this study was to design, synthesize, and initially characterize a representative set of novel constructs for large-molecular radiographic/computed tomography (CT) contrast agents, intended for a primarily intravascular distribution. A new assembly of well-known and biocompatible components consists of paired, symmetrical dendritic polylysines initiated from both ends of a poly(ethylene glycol) (PEG) core, yielding an array of multiple free amino groups to which were conjugated highly soluble and stable triiodophthalamide ("triiodo") moieties. An array of six dendritic contrast agents was synthesized originally, using three different PEG cores (3, 6, 12 kDa) with t-Boc lysine-generated dendrimer "amplifiers" (from three to five generations) containing 16 to 64 amino groups for conjugation with reactive triiodo moieties. A clinically used, nonionic, small molecular CT contrast agent, iobitridol, was derivatized via a hydroxyl protection/deprotection strategy, introducing a new carboxyl group available for conjugation to the lysine amino groups of dendrimers. Final products were purified by size exclusion chromatography and characterized by NMR, UV, HPLC, and elemental analysis. Preliminary evaluations were conducted for physicochemical characterization and in vivo CT contrast enhancement in a rat model. All six iodinated PEG-core dendrimer conjugates were synthesized in good yields, with a high degree of size monodispersity, large apparent molecular weight, favored physicochemical properties. A representative compound, PEG12000-carbamate-Gen4-IOB conjugate, 27% (w%) rich in iodine, demonstrated a desirable strong and persistent intravascular enhancement with a monoexponential blood half-life of approximately 35 min assayed by dynamic CT imaging and also showed high water solubility (>550 mg/mL at 25 degrees C), large apparent molecular size (comparable to a 143-kDa protein), high hydrophilicity (butanol-water partition coefficient 0.015), and

  19. Surveying rip current survivors: preliminary insights into the experiences of being caught in rip currents

    Science.gov (United States)

    Drozdzewski, D.; Shaw, W.; Dominey-Howes, D.; Brander, R.; Walton, T.; Gero, A.; Sherker, S.; Goff, J.; Edwick, B.

    2012-04-01

    This paper begins a process of addressing a significant gap in knowledge about people's responses to being caught in rip currents. While rip currents are the primary hazard facing recreational ocean swimmers in Australia, debate exists about the best advice to give swimmers caught in rip currents. Such surf rescue advice - on what to do and how to respond when caught in a rip - relies on empirical evidence. However, at present, knowledge about swimmers reactions and responses to rip currents is limited. This gap is a considerable barrier to providing effective advice to beach goers and to understanding how this advice is utilised (or not) when actually caught in the rip current. This paper reports the findings of a pilot study that focussed on garnering a better understanding of swimmers' experiences when caught in rip currents. A large scale questionnaire survey instrument generated data about rip current survivors' demographics, knowledge of beach safety and their reactions and responses when caught in a rip current. A mix of online and paper surveys produced a total of 671 completed surveys. Respondents were predominantly an informed group in terms of rip current knowledge, beach experience and had a high self-rated swimming ability. Preliminary insights from the survey show that most respondents recalled a "swim across the rip/parallel to the beach" message when caught in the rip and most escaped unassisted by acting on this message. However, while nearly a quarter of respondents recalled a message of "not to panic", short answer responses revealed that the onset of panic inhibited some respondents from recalling or enacting any other type of beach safety message when caught in the rip current. Results also showed that despite the research sample being younger, competent and frequent ocean swimmers, they were more likely to swim at unpatrolled beaches and outside of the red and yellow safety flags. Moreover, they were still caught in a rip current and they

  20. Preliminary experience in the management of tracheobronchial foreign bodies in Lagos, Nigeria.

    Science.gov (United States)

    Falase, Bode; Sanusi, Michael; Majekodunmi, Adetinuwe; Ajose, Ifeoluwa; Oke, David

    2013-01-01

    Aspiration of tracheobronchial foreign bodies commonly affects young children, is potentially life threatening and requires early intervention for extraction. Access to facilities and skill manpower for bronchoscopic extraction is however limited in Nigeria. The aim of this study is to describe the experience in our institution with bronchoscopic removal of tracheobronchial foreign bodies and highlight the challenges encountered. This is a retrospective study of all patients referred to the Lagos State University Teaching Hospital with a diagnosis of tracheobronchial foreign body within the period of February 2008 and February 2013. Data extracted from the medical records were age, sex, time interval between aspiration and presentation, location of tracheobronchial foreign body, bronchoscopic technique, complications and outcome. A total of 24 patients were referred and confirmed at bronchoscopy to have tracheobronchial foreign bodies. Mean age was 6.6 + 5 years. Male to female ratio was 1:1. Delayed presentation was common with 22 patients (91.7%) presenting more than 24 hours after aspiration. Aspirated material was inorganic in 17 patients (70.8%) and organic in 7 patients (29.2%). Location of tracheobronchial foreign bodies was right main bronchus in 16 patients (66.7%), left main bronchus in 6 patients (25%) and the trachea in 2 patients (8.3%). Challenges to speedy and safe removal of the foreign bodies were delayed presentation and a limited range of bronchoscopic equipment early in the series which caused prolonged procedures and increased complications. Two mortalities occurred early in the series; one from airway obstruction and the other from respiratory failure caused by tracheobronchial oedema. Extraction of tracheobronchial foreign bodies was faster, more complete and safer later in the series due to a wider range of bronchoscopy equipment which included both flexible and rigid videobronchoscopy with the use of optical forceps. This preliminary

  1. Surveying rip current survivors: preliminary insights into the experiences of being caught in rip currents

    Directory of Open Access Journals (Sweden)

    D. Drozdzewski

    2012-04-01

    Full Text Available This paper begins a process of addressing a significant gap in knowledge about people's responses to being caught in rip currents. While rip currents are the primary hazard facing recreational ocean swimmers in Australia, debate exists about the best advice to give swimmers caught in rip currents. Such surf rescue advice – on what to do and how to respond when caught in a rip – relies on empirical evidence. However, at present, knowledge about swimmers reactions and responses to rip currents is limited. This gap is a considerable barrier to providing effective advice to beach goers and to understanding how this advice is utilised (or not when actually caught in the rip current.

    This paper reports the findings of a pilot study that focussed on garnering a better understanding of swimmers' experiences when caught in rip currents. A large scale questionnaire survey instrument generated data about rip current survivors' demographics, knowledge of beach safety and their reactions and responses when caught in a rip current. A mix of online and paper surveys produced a total of 671 completed surveys. Respondents were predominantly an informed group in terms of rip current knowledge, beach experience and had a high self-rated swimming ability. Preliminary insights from the survey show that most respondents recalled a "swim across the rip/parallel to the beach" message when caught in the rip and most escaped unassisted by acting on this message. However, while nearly a quarter of respondents recalled a message of "not to panic", short answer responses revealed that the onset of panic inhibited some respondents from recalling or enacting any other type of beach safety message when caught in the rip current. Results also showed that despite the research sample being younger, competent and frequent ocean swimmers, they were more likely to swim at unpatrolled beaches and outside of the red and yellow safety flags. Moreover, they were still

  2. Geomorphic expression of strike-slip faults: field observations vs. analog experiments: preliminary results

    Science.gov (United States)

    Hsieh, S. Y.; Neubauer, F.; Genser, J.

    2012-04-01

    The aim of this project is to study the surface expression of strike-slip faults with main aim to find rules how these structures can be extrapolated to depth. In the first step, several basic properties of the fault architecture are in focus: (1) Is it possible to define the fault architecture by studying surface structures of the damage zone vs. the fault core, particularly the width of the damage zone? (2) Which second order structures define the damage zone of strike-slip faults, and how relate these to such reported in basement fault strike-slip analog experiments? (3) Beside classical fault bend structures, is there a systematic along-strike variation of the damage zone width and to which properties relates the variation of the damage zone width. We study the above mentioned properties on the dextral Altyn fault, which is one of the largest strike-slip on Earth with the advantage to have developed in a fully arid climate. The Altyn fault includes a ca. 250 to 600 m wide fault valley, usually with the trace of actual fault in its center. The fault valley is confined by basement highs, from which alluvial fans develop towards the center of the fault valley. The active fault trace is marked by small scale pressure ridges and offset of alluvial fans. The fault valley confining basement highs are several kilometer long and ca. 0.5 to 1 km wide and confined by rotated dextral anti-Riedel faults and internally structured by a regular fracture pattern. Dextral anti-Riedel faults are often cut by Riedel faults. Consequently, the Altyn fault comprises a several km wide damage zone. The fault core zone is a barrier to fluid flow, and the few springs of the region are located on the margin of the fault valley implying the fractured basement highs as the reservoir. Consequently, the southern Silk Road was using the Altyn fault valley. The preliminary data show that two or more orders of structures exist. Small-scale develop during a single earthquake. These finally

  3. Gaslini's tracheal team: preliminary experience after one year of paediatric airway reconstructive surgery

    Directory of Open Access Journals (Sweden)

    Torre Michele

    2011-10-01

    single tertiary care Centre providing rapid access to endoscopic and surgical manoeuvres on upper and lower airways and the possibility to start immediately cardiopulmonary bypass or ECMO. The preliminary experience of the Tracheal Team shows that good results can be obtained with this multidisciplinary approach in the treatment of complicated cases. The centralization of all the cases in one or few national Centres should be considered.

  4. Purification, crystallization and preliminary X-ray diffraction experiment of nattokinase from Bacillus subtilis natto.

    Science.gov (United States)

    Yanagisawa, Yasuhide; Chatake, Toshiyuki; Chiba-Kamoshida, Kaori; Naito, Sawa; Ohsugi, Tadanori; Sumi, Hiroyuki; Yasuda, Ichiro; Morimoto, Yukio

    2010-12-01

    Nattokinase is a single polypeptide chain composed of 275 amino acids (molecular weight 27,724) which displays strong fibrinolytic activity. Moreover, it can activate other fibrinolytic enzymes such as pro-urokinase and tissue plasminogen activator. In the present study, native nattokinase from Bacillus subtilis natto was purified using gel-filtration chromatography and crystallized to give needle-like crystals which could be used for X-ray diffraction experiments. The crystals belonged to space group C2, with unit-cell parameters a=74.3, b=49.9, c=56.3 Å, β=95.2°. Diffraction images were processed to a resolution of 1.74 Å with an Rmerge of 5.2% (15.3% in the highest resolution shell) and a completeness of 69.8% (30.0% in the highest resolution shell). This study reports the first X-ray diffraction analysis of nattokinase.

  5. Comparison of image quality between mammography dedicated monitor and UHD 4K monitor, using standard mammographic phantom: A preliminary study

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Ji Young; Cha, Soon Joo; Hong, Sung Hwan; Kim, Su Young; Kim, Yong Hoon; Kim, You Sung; Kim, Jeong A [Dept. of Radiology, Inje Unveristy Ilsan Paik Hospital, Goyang (Korea, Republic of)

    2017-03-15

    Using standard mammographic phantom images, we compared the image quality obtained between a mammography dedicated 5 megapixel monitor (5M) and a UHD 4K (4K) monitor with digital imaging and communications in medicine display, to investigate the possibility of clinical application of 4K monitors. Three different exposures (autoexposure, overexposure and underexposure) images of mammographic phantom were obtained, and six radiologists independently evaluated the images in 5M and 4K without image modulation, by scoring of fibers, groups of specks and masses within the phantom image. The mean score of each object on both monitors was independently analyzed, using t-test and interobserver reliability by intraclass correlation coefficient (ICC) of SPSS. The overall mean scores of fiber, group of specks, and mass in 5M were 4.25, 3.92, and 3.28 respectively, and scores obtained in 4K monitor were 3.81, 3.58, and 3.14, respectively. No statistical difference was seen in scores of fiber and mass between the two monitors at all exposure conditions, but the score of group of specks in 4K was statistically lower in the overall (p = 0.0492) and in underexposure conditions (p = 0.012). The ICC for interobserver reliability was excellent (0.874). Our study suggests that since the mammographic phantom images are appropriate with no significant difference in image quality observed between the two monitors, the 4K monitor could be used for clinical studies. Since this is a small preliminary study using phantom images, the result may differ in actual mammographic images, and subsequent investigation with clinical mammographic images is required.

  6. Preliminary experiments to estimate the PE.MA.M (PElagic MArine Mesocosm) offshore behaviour

    Science.gov (United States)

    Albani, Marta; Piermattei, Viviana; Stefanì, Chiara; Marcelli, Marco

    2016-04-01

    The phytoplankton community is controlled not only by local environmental conditions but also by physical processes occurring on different temporal and spatial scales. Hydrodynamic local conditions play an important role in marine ecosystems. Several studies have shown that hydrodynamic conditions can influence the phytoplankton settling velocity, vertical and horizontal distribution and formation of cyanobacterial blooms. Mesocosms are useful structures to simulate marine environment at mesoscale resolution; allowing to closely approximate biotic or abiotic parameters of interest directly in nature. In this work an innovative structure named PE.MA.M (PElagic MArine Mesocosm) is presented and tested. Laboratory experiments have been conducted in order to observe seasonal variations of biomass behaviour in two different hydrodynamic conditions: outside as well as whithin the PE.MA.M. We have evaluated whether it is possible to isolate a natural system from external water mass hydrodynamic exchanges and to assume that phytoplankton cells' transition is limited at the net and sea interface. Preliminary experiments test the isolating capacity of the net, to determine the currents' attenuation rate and to estimate the possible PE.MA.M. offshore behaviour. In the first investigation, we monitored the diffusion of phytoplankton cells. The PE.MA.M. exterior and interior were simulated using a plexiglass tank divided into two half-tanks (Aout-Bin) by a septum consisting of a net like a PE.MA.M. The tank was filled up with 10 L of water and only the half-tank Aout was filled up with 10 ml of phytoplankton culture (Clorella sp.). We monitored the chlorophyll concentrations for 24 hours. The two tanks had similar concentrations after 4 hours (2.70322 mg/m³ Aout and 2.37245 mg/m3 Bin) and this constant relationship was maintened until the end of the test. In the second investigation we used clod cards to measure water motions.We conducted two experiments within tank, the first

  7. Preliminary Image Map of the 2007 Witch Fire Perimeter, Rancho Santa Fe Quadrangle, San Diego County, California

    Science.gov (United States)

    Clark, Perry S.; Scratch, Wendy S.; Bias, Gaylord W.; Stander, Gregory B.; Sexton, Jenne L.; Krawczak, Bridgette J.

    2008-01-01

    In the fall of 2007, wildfires burned out of control in southern California. The extent of these fires encompassed large geographic areas that included a variety of landscapes from urban to wilderness. The U.S. Geological Survey National Geospatial Technical Operations Center (NGTOC) is currently (2008) developing a quadrangle-based 1:24,000-scale image map product. One of the concepts behind the image map product is to provide an updated map in electronic format to assist with emergency response. This image map is one of 55 preliminary image map quadrangles covering the areas burned by the southern California wildfires. Each map is a layered, geo-registered Portable Document Format (.pdf) file. For more information about the layered geo-registered .pdf, see the readme file (http://pubs.usgs.gov/of/2008/1029/downloads/CA_Agua_Dulce_of2008-1029_README.txt). To view the areas affected and the quadrangles mapped in this preliminary project, see the map index (http://pubs.usgs.gov/of/2008/1029/downloads/CA_of2008_1029-1083_index.pdf) provided with this report.

  8. Preliminary Image Map of the 2007 Ranch Fire Perimeter, Whitaker Peak Quadrangle, Los Angeles and Ventura Counties, California

    Science.gov (United States)

    Clark, Perry S.; Scratch, Wendy S.; Bias, Gaylord W.; Stander, Gregory B.; Sexton, Jenne L.; Krawczak, Bridgette J.

    2008-01-01

    In the fall of 2007, wildfires burned out of control in southern California. The extent of these fires encompassed large geographic areas that included a variety of landscapes from urban to wilderness. The U.S. Geological Survey National Geospatial Technical Operations Center (NGTOC) is currently (2008) developing a quadrangle-based 1:24,000-scale image map product. One of the concepts behind the image map product is to provide an updated map in electronic format to assist with emergency response. This image map is one of 55 preliminary image map quadrangles covering the areas burned by the southern California wildfires. Each map is a layered, geo-registered Portable Document Format (.pdf) file. For more information about the layered geo-registered .pdf, see the readme file (http://pubs.usgs.gov/of/2008/1029/downloads/CA_Agua_Dulce_of2008-1029_README.txt). To view the areas affected and the quadrangles mapped in this preliminary project, see the map index (http://pubs.usgs.gov/of/2008/1029/downloads/CA_of2008_1029-1083_index.pdf) provided with this report.

  9. Preliminary Image Map of the 2007 Ammo Fire Perimeter, Las Pulgas Canyon Quadrangle, San Diego County, California

    Science.gov (United States)

    Clark, Perry S.; Scratch, Wendy S.; Bias, Gaylord W.; Stander, Gregory B.; Sexton, Jenne L.; Krawczak, Bridgette J.

    2008-01-01

    In the fall of 2007, wildfires burned out of control in southern California. The extent of these fires encompassed large geographic areas that included a variety of landscapes from urban to wilderness. The U.S. Geological Survey National Geospatial Technical Operations Center (NGTOC) is currently (2008) developing a quadrangle-based 1:24,000-scale image map product. One of the concepts behind the image map product is to provide an updated map in electronic format to assist with emergency response. This image map is one of 55 preliminary image map quadrangles covering the areas burned by the southern California wildfires. Each map is a layered, geo-registered Portable Document Format (.pdf) file. For more information about the layered geo-registered .pdf, see the readme file (http://pubs.usgs.gov/of/2008/1029/downloads/CA_Agua_Dulce_of2008-1029_README.txt). To view the areas affected and the quadrangles mapped in this preliminary project, see the map index (http://pubs.usgs.gov/of/2008/1029/downloads/CA_of2008_1029-1083_index.pdf) provided with this report.

  10. P and S-wave tomographic images for the PASSCAL experiments

    Science.gov (United States)

    Yuan, H.; Dueker, K.

    2001-12-01

    We present teleseismic P and S-wave tomographic images down to 400 Km for the PASSCAL CD-ROM teleseismic experiment. Our aim is to investigate the structural variations across the Archean-Proterozoic Cheyenne Belt (the North line) and across the Proterozoic-Proterozoic Jemez volcanic lineament (the South line). A full year of teleseismic P and S-wave data was collected from 48 PASSCAL broadband 3-component instruments. S phases were rotated to the direction of maximum linear polarization. A multi-channel cross correlation technique was used to measure the arrival times. We picked 1400 travel-time residuals for the teleseismic S, ScS and SKS phases and 2000 for P. An iterative LSQR matrix solver with Laplacian regulation was applied to invert the data for P and S wave images. Our preliminary results show large peak-to-peak teleseismic residuals, i.e., 2 sec P-time variations and 5 sec S-wave variations. The peak-to-peak S velocity difference reaches 12%. In the CD-ROM North line a fast anomaly appears north of CB, which is consistent with the cold, stable Archean craton. To the south this feature vanishes across the Cheyenne Belt (N 41.25 deg). The south line shows a large low velocity zone extending to 200 km beneath the Jemez volcanic lineament. The P-wave and S-wave images are highly correlated with a dnVp/dlnVs ratio of about 2. Images from two different PASSCAL experiments, the Lodore and Laramie array, share the complexities of the seismic velocity variation beneath the CD-ROM transects. A joint inversion of the P and S and a delta t-star data are proposed to further constrain the thermal state and composition state of the active upper mantle beneath the Wyoming, Colorado and New Mexico regions.

  11. The Ring Imaging CHerenkov Detectors of the LHCb Experiment

    CERN Document Server

    Perego, Davide Luigi

    2012-01-01

    Particle identification is a fundamental requirement of the LHCb experiment to fulfill its physics programme. Positive hadron identification is performed by two Ring Imaging CHerenkov (RICH) detectors. This system covers the full angular acceptance of the experiment and is equipped with three Cherenkov radiators to identify particles in a wide momentum range from1 GeV/ c up to 100 GeV/ c . The Hybrid Photon Detectors (HPDs) located outside the detector acceptance provide the photon detection with 500,000 channels. Specific read–out electronics has been developed to readout and process data from the HPDs including data transmission and power distribution. The operation and performanceoftheRICHsystemare ensuredbythe constant controland monitoringoflowandhighvoltage systems,of thegas qualityandenvironmental parameters,ofthe mirror alignment,and finallyofthe detector safety. The description of the LHCb RICH is given. The experience in operating the detector at the Large Hadron Collider is presented and discusse...

  12. Cardiac biplane strain imaging: initial in vivo experience

    Science.gov (United States)

    Lopata, R. G. P.; Nillesen, M. M.; Verrijp, C. N.; Singh, S. K.; Lammens, M. M. Y.; van der Laak, J. A. W. M.; van Wetten, H. B.; Thijssen, J. M.; Kapusta, L.; de Korte, C. L.

    2010-02-01

    In this study, first we propose a biplane strain imaging method using a commercial ultrasound system, yielding estimation of the strain in three orthogonal directions. Secondly, an animal model of a child's heart was introduced that is suitable to simulate congenital heart disease and was used to test the method in vivo. The proposed approach can serve as a framework to monitor the development of cardiac hypertrophy and fibrosis. A 2D strain estimation technique using radio frequency (RF) ultrasound data was applied. Biplane image acquisition was performed at a relatively low frame rate (cardiac cycle in four dogs with an aortic stenosis. Initial results reveal the feasibility of measuring large radial, circumferential and longitudinal cumulative strain (up to 70%) at a frame rate of 100 Hz. Mean radial strain curves of a manually segmented region-of-interest in the infero-lateral wall show excellent correlation between the measured strain curves acquired in two perpendicular planes. Furthermore, the results show the feasibility and reproducibility of assessing radial, circumferential and longitudinal strains simultaneously. In this preliminary study, three beagles developed an elevated pressure gradient over the aortic valve (Δp: 100-200 mmHg) and myocardial hypertrophy. One dog did not develop any sign of hypertrophy (Δp = 20 mmHg). Initial strain (rate) results showed that the maximum strain (rate) decreased with increasing valvular stenosis (-50%), which is in accordance with previous studies. Histological findings corroborated these results and showed an increase in fibrotic tissue for the hearts with larger pressure gradients (100, 200 mmHg), as well as lower strain and strain rate values.

  13. Students' Ideas about Prismatic Images: Teaching Experiments for an Image-Based Approach

    Science.gov (United States)

    Grusche, Sascha

    2017-01-01

    Prismatic refraction is a classic topic in science education. To investigate how undergraduate students think about prismatic dispersion, and to see how they change their thinking when observing dispersed images, five teaching experiments were done and analysed according to the Model of Educational Reconstruction. For projection through a prism,…

  14. Preliminary planning study for safety relief valve experiments in a Mark III BWR pressure suppression system

    Energy Technology Data Exchange (ETDEWEB)

    McCauley, E.W.; Holman, G.S.

    1980-04-21

    In response to a request from the Water Reactor Safety Research Division of the US NRC, a preliminary study is provided which identifies key features and consideration involved in planning a comprehensive in-plant Safety Relief Valve experimental program for a Mark III containment design. The report provides identification of program objectives, measurement system requirements, and some details quantifying expected system response. In addition, a preliminary test matrix is outlined which involves a supporting philosophy intended to enhance the usefulness of the experimental results for all members of the program team: experimentalists, analysts, and plant operator.

  15. A new extra-abdominal channel alternative to the mitrofanoff principle: experimental and preliminary clinical experience

    Directory of Open Access Journals (Sweden)

    Antonio Macedo Jr.

    2009-04-01

    Full Text Available INTRODUCTION: The appendix is the gold-standard channel for the Mitrofanoff principle in pediatric urology, but the search for alternatives is justified considering it may not be available or preferably used for colonic stomas (Malone antegrade continence enema. The aim of this study is to report on technical feasibility of a new approach for creating catheterizable channels in a rabbit model and to present our preliminary clinical experience. MATERIAL AND METHODS: We configured a tube from two rectangular skin flaps 1x4 cm opposite each other in the middle line of the lower inferior abdomen. The channel was anastomosed to the bladder dome with embedding sutures to create a valvular mechanism. The experimental study consisted of 12 rabbits, divided in 4 groups according to the sacrifice schedule at 2, 4, 8 and 12 weeks. At 30th postoperative day, an urodynamic evaluation was performed to record continence of the stoma. A histological analysis of the specimens stained with hematoxylin-eosin, Masson trichrome and Picrosirius red was also done in group 2 (sacrifice at 4 weeks postoperatively. We used this method in 3 patients with congenital non-neurogenic bladder disease presenting with massive residual volumes without compliance deficits. RESULT: The technique proved feasible in all animals, 9 of 12 could be easily catheterized and underwent urodynamic study. No stoma leakage was observed in 7 animals at high bladder pressures (> 50 cm H20 and only 2 animals had some leakage at 40 cm H20. Urodynamics performed through the stoma showed urethral leakage at 20 cm H20, therefore demonstrating the efficacy of the valvular mechanism. Histological analysis confirmed good integration between the tube and the bladder. Mean follow-up of the clinical series (3 patients was 7.2 months. Two patients remained continent up to 4 hours, whereas 1 patient had some leakage after 2 hours. CONCLUSION: We were able to confirm feasibility of a new extra

  16. Only fixation for cervical spondylosis: Report of early results with a preliminary experience with 6 cases

    Directory of Open Access Journals (Sweden)

    Atul Goel

    2013-01-01

    Full Text Available Aim: The author reports early post-operative outcome and preliminary experience with an alternative form of treatment of cervical degenerative or spondylotic disease leading to spinal canal stenosis that involves fixation-arthrodesis of the affected spinal segment using one or two (double insurance transarticular screws for each joint. Materials and Methods: During the period of months from March 2013 to July 2013, six patients having cervical spondylotic cord compression were treated with transarticular method of screw fixation of the involved segments. The operation involved section of the spinous process at its base, opening up of the facet joint, denuding of articular cartilage, placement of intraarticular cavity bone graft chips and insertion of either a single or two transarticular screws at each level. The fixation was done in four levels in four patients and at two levels in two patients. Japanese Orthopedic Association score, visual analog scale (neck pain and Odom′s criteria were used to monitor the clinical status of the patients before and after the surgery and at follow-up. Results: Immediate post-operative and a relatively short-term post-operative outcome was remarkably gratifying. During the average period of follow-up of 6 months (range: 3-8 months; there was varying degree of recovery of symptoms. The procedure resulted in firm stabilization and fixation of the spinal segment and provided a ground for arthrodesis. No patient worsened after treatment. During the period of follow-up, all patients showed remarkable and progressive recovery in symptoms. Conclusions: Vertical instability and telescoping, listhesis or overriding of the facets on physical activity seems to be the defining phenomenon in pathogenesis of cervical spondylotic disease. The clinical outcome in our patients suggest that only fixation of the spinal segment can be a rationale form of treatment. Transarticular method of treatment is a simple, safe and

  17. Microwave thermal imaging of scanned focused ultrasound heating: animal experiments

    Science.gov (United States)

    Zhou, Tian; Meaney, Paul M.; Hoopes, P. Jack; Geimer, Shireen D.; Paulsen, Keith D.

    2011-03-01

    High intensity focused ultrasound (HIFU) uses focused ultrasound beams to ablate localized tumors noninvasively. Multiple clinical trials using HIFU treatment of liver, kidney, breast, pancreas and brain tumors have been conducted, while monitoring the temperature distribution with various imaging modalities such as MRI, CT and ultrasound. HIFU has achieved only minimal acceptance partially due to insufficient guidance from the limited temperature monitoring capability and availability. MR proton resonance frequency (PRF) shift thermometry is currently the most effective monitoring method; however, it is insensitive in temperature changes in fat, susceptible to motion artifacts, and is high cost. Exploiting the relationship between dielectric properties (i.e. permittivity and conductivity) and tissue temperature, in vivo dielectric property distributions of tissue during heating were reconstructed with our microwave tomographic imaging technology. Previous phantom studies have demonstrated sub-Celsius temperature accuracy and sub-centimeter spatial resolution in microwave thermal imaging. In this paper, initial animal experiments have been conducted to further investigate its potential. In vivo conductivity changes inside the piglet's liver due to focused ultrasound heating were observed in the microwave images with good correlation between conductivity changes and temperature.

  18. Preliminary diffusion tensor imaging studies in limb-girdle muscular dystrophies

    Science.gov (United States)

    Hidalgo-Tobon, S.; Hernandez-Salazar, G.; Vargas-Cañas, S.; Marrufo-Melendez, O.; Solis-Najera, S.; Taboada-Barajas, J.; Rodriguez, A. O.; Delgado-Hernandez, R.

    2012-10-01

    Limb-girdle muscular dystrophies (LGMD) are a group of autosomal dominantly or recessively inherited muscular dystrophies that also present with primary proximal (limb-girdle) muscle weakness. This type of dystrophy involves the shoulder and pelvic girdles, distinct phenotypic or clinical characteristics are recognized. Imaging experiments were conducted on a 1.5T GE scanner (General Electric Medical Systems. Milwaukee. USA), using a combination of two eight-channel coil array. Diffusion Tensor Imaging (DTI) data were acquired using a SE-EPI sequence, diffusion weighted gradients were applied along 30 non-collinear directions with a b-value=550 s/mm2. The connective tissue content does not appear to have a significant effect on the directionality of the diffusion, as assessed by fractional anisotropy. The fibers of the Sartorius muscle and gracilis showed decreased number of tracts, secondary to fatty infiltration and replacement of connective tissue and muscle mass loss characteristic of the underlying pathology. Our results demonstrated the utility of non-invasive MRI techniques to characterize the muscle pathology, through quantitative and qualitative methods such as the FA values and tractrography.

  19. SU-E-I-74: Image-Matching Technique of Computed Tomography Images for Personal Identification: A Preliminary Study Using Anthropomorphic Chest Phantoms

    Energy Technology Data Exchange (ETDEWEB)

    Matsunobu, Y; Shiotsuki, K [Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka (Japan); Morishita, J [Department of Health Sciences, Faculty of Medical Sciences, Kyushu University, Fukuoka, JP (Japan)

    2015-06-15

    Purpose: Fingerprints, dental impressions, and DNA are used to identify unidentified bodies in forensic medicine. Cranial Computed tomography (CT) images and/or dental radiographs are also used for identification. Radiological identification is important, particularly in the absence of comparative fingerprints, dental impressions, and DNA samples. The development of an automated radiological identification system for unidentified bodies is desirable. We investigated the potential usefulness of bone structure for matching chest CT images. Methods: CT images of three anthropomorphic chest phantoms were obtained on different days in various settings. One of the phantoms was assumed to be an unidentified body. The bone image and the bone image with soft tissue (BST image) were extracted from the CT images. To examine the usefulness of the bone image and/or the BST image, the similarities between the two-dimensional (2D) or threedimensional (3D) images of the same and different phantoms were evaluated in terms of the normalized cross-correlation value (NCC). Results: For the 2D and 3D BST images, the NCCs obtained from the same phantom assumed to be an unidentified body (2D, 0.99; 3D, 0.93) were higher than those for the different phantoms (2D, 0.95 and 0.91; 3D, 0.89 and 0.80). The NCCs for the same phantom (2D, 0.95; 3D, 0.88) were greater compared to those of the different phantoms (2D, 0.61 and 0.25; 3D, 0.23 and 0.10) for the bone image. The difference in the NCCs between the same and different phantoms tended to be larger for the bone images than for the BST images. These findings suggest that the image-matching technique is more useful when utilizing the bone image than when utilizing the BST image to identify different people. Conclusion: This preliminary study indicated that evaluating the similarity of bone structure in 2D and 3D images is potentially useful for identifying of an unidentified body.

  20. The MARTE VNIR Imaging Spectrometer Experiment: Design and Analysis

    CERN Document Server

    Brown, Adrian J; Dunagan, Stephen

    2014-01-01

    We report on the design, operation, and data analysis methods employed on the VNIR imaging spectrometer instrument that was part of the Mars Astrobiology Research and Technology Experiment (MARTE). The imaging spectrometer is a hyperspectral scanning pushbroom device sensitive to VNIR wavelengths from 400-1000 nm. During the MARTE project, the spectrometer was deployed to the Rio Tinto region of Spain. We analyzed subsets of 3 cores from Rio Tinto using a new band modeling technique. We found most of the MARTE drill cores to contain predominantly goethite, though spatially coherent areas of hematite were identified in Core 23. We also distinguished non Fe-bearing minerals that were subsequently analyzed by X-ray diffraction (XRD) and found to be primarily muscovite. We present drill core maps that include spectra of goethite, hematite, and non Fe-bearing minerals.

  1. Preliminary data for the 20 May 1974, simultaneous evaluation of remote sensors experiment. [water pollution monitoring

    Science.gov (United States)

    Johnson, R. W.; Batten, C. E.; Bowker, D. E.; Bressette, W. E.; Grew, G. W.

    1975-01-01

    Several remote sensors were simultaneously used to collect data over the tidal James River from Hopewell to Norfolk, Virginia. Sensors evaluated included the Multichannel-Ocean Color Sensor, multispectral scanners, and multispectral photography. Ground truth measurements and remotely sensed data are given. Preliminary analysis indicates that suspended sediment and concentrated industrial effluent are observable from all sensors.

  2. Image processing analysis of traditional Gestalt vision experiments

    Science.gov (United States)

    McCann, John J.

    2002-06-01

    In the late 19th century, the Gestalt Psychology rebelled against the popular new science of Psychophysics. The Gestalt revolution used many fascinating visual examples to illustrate that the whole is greater than the sum of all the parts. Color constancy was an important example. The physical interpretation of sensations and their quantification by JNDs and Weber fractions were met with innumerable examples in which two 'identical' physical stimuli did not look the same. The fact that large changes in the color of the illumination failed to change color appearance in real scenes demanded something more than quantifying the psychophysical response of a single pixel. The debates continues today with proponents of both physical, pixel-based colorimetry and perceptual, image- based cognitive interpretations. Modern instrumentation has made colorimetric pixel measurement universal. As well, new examples of unconscious inference continue to be reported in the literature. Image processing provides a new way of analyzing familiar Gestalt displays. Since the pioneering experiments by Fergus Campbell and Land, we know that human vision has independent spatial channels and independent color channels. Color matching data from color constancy experiments agrees with spatial comparison analysis. In this analysis, simple spatial processes can explain the different appearances of 'identical' stimuli by analyzing the multiresolution spatial properties of their surrounds. Benary's Cross, White's Effect, the Checkerboard Illusion and the Dungeon Illusion can all be understood by the analysis of their low-spatial-frequency components. Just as with color constancy, these Gestalt images are most simply described by the analysis of spatial components. Simple spatial mechanisms account for the appearance of 'identical' stimuli in complex scenes. It does not require complex, cognitive processes to calculate appearances in familiar Gestalt experiments.

  3. A Preliminary Mapping of Web Queries Using Existing Image Query Schemes.

    Science.gov (United States)

    Jansen, Bernard J.

    End user searching on the Web has become the primary method of locating images for many people. This study investigates the nature of Web image queries by attempting to map them to known image classification schemes. In this study, approximately 100,000 image queries from a major Web search engine were collected in 1997, 1999, and 2001. A…

  4. Solid Hydrogen Experiments for Atomic Propellants: Image Analyses

    Science.gov (United States)

    Palaszewski, Bryan

    2002-01-01

    This paper presents the results of detailed analyses of the images from experiments that were conducted on the formation of solid hydrogen particles in liquid helium. Solid particles of hydrogen were frozen in liquid helium, and observed with a video camera. The solid hydrogen particle sizes, their agglomerates, and the total mass of hydrogen particles were estimated. Particle sizes of 1.9 to 8 mm (0.075 to 0.315 in.) were measured. The particle agglomerate sizes and areas were measured, and the total mass of solid hydrogen was computed. A total mass of from 0.22 to 7.9 grams of hydrogen was frozen. Compaction and expansion of the agglomerate implied that the particles remain independent particles, and can be separated and controlled. These experiment image analyses are one of the first steps toward visually characterizing these particles, and allow designers to understand what issues must be addressed in atomic propellant feed system designs for future aerospace vehicles.

  5. Towards a quantitative study of the VUV photolysis of methane: preliminary experiment on trichloromethane

    Science.gov (United States)

    Gans, B.; Boyé-Péronne, S.; Douin, S.; Gauyacq, D.

    2010-01-01

    Photolysis of methane in Titan's stratosphere is the starting point of gas phase carbon chemistry. Quantitative studies of methane photolytic products are of utmost importance for Titan atmosphere models. With this aim, two experimental strategies are presented in this article. Preliminary results demonstrate the possibility of using CRDS absorption coupled with pulsed photolysis on the example of a halogenated derivative of methane: Trichloromethane (CHCl_3).

  6. Mass transport phenomena during solidification in microgravity; preliminary results of the first Mephisto flight experiment

    Science.gov (United States)

    Favier, J. J.; Garandet, J. P.; Rouzaud, A.; Camel, D.

    1994-06-01

    The MEPHISTO space facility flew on the Columbia space shuttle in October 1992. The preliminary scientific results, mainly based on the analysis of the Seebeck signal, are presented in this paper. Valuable information was obtained for both planar and cellular solidification regimes. It is shown that mass transfer in the melt during the flight was principally diffusive; however, even in microgravity, slow growth rates may result in significant convective transport. A tentative interpretation of the Seebeck signal for destabilized interfaces is also proposed.

  7. Preliminary results of Resistive Plate Chambers operated with eco-friendly gas mixtures for application in the CMS experiment

    CERN Document Server

    Abbrescia, M

    2016-01-01

    The operations of Resistive Plate Chambers in LHC experiments require Fluorine based (F-based) gases for optimal performance. Recent European regulations demand the use of environmentally unfriendly F-based gases to be limited or banned. In view of the CMS experiment upgrade, several tests are ongoing to measure the performance of the detector with these new ecological gas mixtures, in terms of efficiency, streamer probability, induced charge and time resolution. Prototype chambers with readout pads and with the standard CMS electronic setup are under test. In this paper preliminary results on performance of RPCs operated with a potential eco-friendly gas candidate 1,3,3,3-Tetrafluoropropene, commercially known as HFO-1234ze, with CO2 and CF3I based gas mixtures are presented and discussed for the possible application in the CMS experiment.

  8. Preliminary results of Resistive Plate Chambers operated with eco-friendly gas mixtures for application in the CMS experiment

    CERN Document Server

    Abbrescia, Marcello; Benussi, Luigi; Bianco, Stefano; Cauwenbergh, Simon Marc D; Ferrini, Mauro; Muhammad, Saleh; Passamontic, L; Pierluigi, Daniele; Piccolo, Davide; Primavera, Federica; Russo, Alessandro; Savianoc, G; Tytgat, Michael

    2016-01-01

    The operations of Resistive Plate Chambers in LHC experiments require F-based gases for optimal performance. Recent regulations demand the use of environmentally unfriendly F-based gases to be limited or banned. In view of the CMS experiment upgrade several tests are ongoing to measure the performance of the detector in terms of efficiency, streamer probability, induced charge and time resolution. Prototype chambers with readout pads and with the standard cms electronic setup are under test. In this talk preliminary results on performance of RPCs operated with a potential eco-friendly gas candidate 1,3,3,3-Tetrafluoropropene, commercially known as HFO-1234ze and with CO2 based gas mixtures are presented and discussed for the possible application in the CMS experiment.

  9. Fusion of intravenous contrast-enhanced C-arm CT and pretreatment imaging for ablation margin assessment of liver tumors: A preliminary study

    Directory of Open Access Journals (Sweden)

    Jin Iwazawa

    2012-01-01

    Full Text Available The aim of this preliminary study was to evaluate the feasibility of assessing ablation margins after radiofrequency ablation (RFA of liver tumors from fusion images of post-treatment C-arm computed tomography (CT images fused to pretreatment images. Five patients with liver tumors underwent RFA. Intravenous contrast-enhanced C-arm CT images were obtained for all patients immediately after RFA, and multi-detector CT (MDCT images were obtained 3-7 days later. The C-arm CT and MDCT images were fused to pretreatment images using a multimodality image fusion software. The minimum ablation margins were assessed in the C-arm CT and MDCT fusion images. Ablation margins after RFA of liver tumors can be measured using intravenous contrast-enhanced C-arm CT images fused with pretreatment images. This technique has the potential for use in the intra-procedural assessment of liver tumor ablation.

  10. Hydrogeological characterization of the Heletz Sands Reservoir, Heletz (Israel) as a preliminary step towards CO2 injection experiments

    Science.gov (United States)

    Bensabat, Jacob; Niemi, Auli; Tsang, Chin-Fu; Sharma, Prabhakar; Carrera, Jesus; Sauter, Martin; Tatomir, Alexandru; Ghergut, Julia; Pezard, Philippe; Edlman, Katriona; Brauchler, Ralf

    2013-04-01

    Hydrogeological characterization of the Heletz Sands Reservoir, Heletz (Israel) as a preliminary step towards CO2 injection experiments One the major components of the EU-FP7 funded MUSTANG project is to conduct a highly controlled series of CO2 injection experiments, aimed at determining field values of key CO2 trapping mechanisms such as dissolution and residual trapping and to establish a comprehensive and consistent dataset for model validation. Prior to injecting CO2 there is a need to achieve a sufficient degree of hydrogeological characterization of the reservoir. In what follows we present a sequence of hydrologic tests to be conducted at Heletz and their expected contribution to the understanding relevant hydrogeology. These include: 1) Chemical characterization of the formation fluid; 2) Flowing Fluid Electrical Conductivity log, aimed at determining the vertical variability of the reservoir permeability in the near well vicinity; 3) Water pulse and pumping tests, aimed at determining the reservoir scale hydraulic properties; 4) Thermal test, aimed at determining the value of the heat transfer coefficient from the reservoir to the borehole fluid, which is responsible for the heating of injected fluid in the borehole; 5) two-well injection and pumping of water and tracers test, in order to determine the impact of heterogeneity on the hydraulic parameters and to identify preferential flow paths in the reservoir. This paper presents the design and planning of the experiments, the results obtained in field and a preliminary interpretation.

  11. Application of Computed Tomography Virtual Noncontrast Spectral Imaging in Evaluation of Hepatic Metastases: A Preliminary Study

    Institute of Scientific and Technical Information of China (English)

    Shi-Feng Tian; Ai-Lian Liu; Jing-Hong Liu; Mei-Yu Sun; He-Qing Wang; Yi-Jun Liu

    2015-01-01

    Objective:The objective was to qualitatively and quantitatively evaluate hepatic metastases using computed tomography (CT) virtual noncontrast (VNC) spectral imaging in a retrospective analysis.Methods:Forty hepatic metastases patients underwent CT scans including the conventional true noncontrast (TNC) and the tri-phasic contrast-enhanced dual energy spectral scans in the hepatic arterial,portal venous,and equilibrium phases.The tri-phasic spectral CT images were used to obtain three groups of VNC images including in the arterial (VNCa),venous (VNCv),and equilibrium (VNCe) phase by the material decomposition process using water and iodine as a base material pair.The image quality and the contrast-to-noise ratio (CNR) of metastasis of the four groups were compared with ANOVA analysis.The metastasis detection rates with the four nonenhanced image groups were calculated and compared using the Chi-square test.Results:There were no significant differences in image quality among TNC,VNCa and VNCv images (P > 0.05).The quality of VNCe images was significantly worse than that of other three groups (P < 0.05).The mean CNR of metastasis in the TNC and VNCs images was 1.86,2.42,1.92,and 1.94,respectively; the mean CNR of metastasis in VNCa images was significantly higher than that in other three groups (P < 0.05),while no statistically significant difference was observed among VNCv,VNCe and TNC images (P > 0.05).The metastasis detection rate of the four nonenhanced groups with no statistically significant difference (P > 0.05).Conclusions:The quality of VNCa and VNCv images is identical to that of TNC images,and the metastasis detection rate in VNC images is similar to that in TNC images.VNC images obtained from arterial phase show metastases more clearly.Thus,VNCa imaging may be a surrogate to TNC imaging in hepatic metastasis diagnosis.

  12. The Thirty Gigahertz Instrument Receiver for the QUIJOTE Experiment: Preliminary Polarization Measurements and Systematic-Error Analysis.

    Science.gov (United States)

    Casas, Francisco J; Ortiz, David; Villa, Enrique; Cano, Juan L; Cagigas, Jaime; Pérez, Ana R; Aja, Beatriz; Terán, J Vicente; de la Fuente, Luisa; Artal, Eduardo; Hoyland, Roger; Génova-Santos, Ricardo

    2015-08-05

    This paper presents preliminary polarization measurements and systematic-error characterization of the Thirty Gigahertz Instrument receiver developed for the QUIJOTE experiment. The instrument has been designed to measure the polarization of Cosmic Microwave Background radiation from the sky, obtaining the Q, U, and I Stokes parameters of the incoming signal simultaneously. Two kinds of linearly polarized input signals have been used as excitations in the polarimeter measurement tests in the laboratory; these show consistent results in terms of the Stokes parameters obtained. A measurement-based systematic-error characterization technique has been used in order to determine the possible sources of instrumental errors and to assist in the polarimeter calibration process.

  13. A PRELIMINARY STUDY ON COMPARISON AND FUSION OF METABOLIC IMAGES OF PET WITH ANATOMIC IMAGES OF CT AND MRI

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Objective. To compare and match metabolic images of PET with anatomic images of CT and MRI. Methods. The CT or MRI images of the patients were obtained through a photo scanner, and then transferred to the remote workstation of PET scanner with a floppy disk. A fusion method was developed to match the 2-dimensional CT or MRI slices with the correlative slices of 3-dimensional volume PET images. Results. Twenty- nine metabolically changed foci were accurately localized in 21 epilepsy patients' MRI images, while MRI alone had only 6 true positive findings. In 53 cancer or suspicious cancer patients, 53 positive lesions detected by PET were compared and matched with the corresponding lesions in CT or MRI images, in which 10 lesions were missed. On the other hand, 23 lesions detected from the patients' CT or MRI images were negative or with low uptake in the PET images, and they were finally proved as benign. Conclusions. Comparing and matching metabolic images with anatomic images helped obtain a full understanding about the lesion and its peripheral structures. The fusion method was simple, practical and useful for localizing metabolically changed lesions.

  14. Preliminary clinical results: an analyzing tool for 2D optical imaging in detection of active inflammation in rheumatoid arthritis

    Science.gov (United States)

    Adi Aizudin Bin Radin Nasirudin, Radin; Meier, Reinhard; Ahari, Carmen; Sievert, Matti; Fiebich, Martin; Rummeny, Ernst J.; No"l, Peter B.

    2011-03-01

    Optical imaging (OI) is a relatively new method in detecting active inflammation of hand joints of patients suffering from rheumatoid arthritis (RA). With the high number of people affected by this disease especially in western countries, the availability of OI as an early diagnostic imaging method is clinically highly relevant. In this paper, we present a newly in-house developed OI analyzing tool and a clinical evaluation study. Our analyzing tool extends the capability of existing OI tools. We include many features in the tool, such as region-based image analysis, hyper perfusion curve analysis, and multi-modality image fusion to aid clinicians in localizing and determining the intensity of inflammation in joints. Additionally, image data management options, such as the full integration of PACS/RIS, are included. In our clinical study we demonstrate how OI facilitates the detection of active inflammation in rheumatoid arthritis. The preliminary clinical results indicate a sensitivity of 43.5%, a specificity of 80.3%, an accuracy of 65.7%, a positive predictive value of 76.6%, and a negative predictive value of 64.9% in relation to clinical results from MRI. The accuracy of inflammation detection serves as evidence to the potential of OI as a useful imaging modality for early detection of active inflammation in patients with rheumatoid arthritis. With our in-house developed tool we extend the usefulness of OI imaging in the clinical arena. Overall, we show that OI is a fast, inexpensive, non-invasive and nonionizing yet highly sensitive and accurate imaging modality.-

  15. Manual khalifa therapy in patients with completely ruptured anterior cruciate ligament in the knee: First preliminary results from thermal imaging

    Directory of Open Access Journals (Sweden)

    Gerhard Litscher

    2013-01-01

    Full Text Available Background: This preliminary publication describes acute temperature effects after manual Khalifa therapy. Aims : The goal of this study was to describe temperature distribution and the effects on surface temperature of the knees and feet in patients with completely ruptured anterior cruciate ligament before and immediately after the manual therapy. Materials and Methods: Ten male patients were investigated with thermal imaging. An infrared camera operating at a wavelength range of 7.5-13 μm was used. Temperature was analyzed at three locations on both knees and in addition on both feet. Results: The study revealed that baseline temperature of the injured knee differed from that of the untreated control knee. After the therapy on the injured knee, the surface temperature was significantly increased on both knees (injured and control. There were no significant changes in the temperature of the feet. Conclusions: Further studies using continuous thermal image recording may help to explain the details concerning the temperature distribution.

  16. A dual-modality photoacoustic and ultrasound imaging system for noninvasive sentinel lymph node detection: preliminary clinical results

    Science.gov (United States)

    Erpelding, Todd N.; Garcia-Uribe, Alejandro; Krumholz, Arie; Ke, Haixin; Maslov, Konstantin; Appleton, Catherine; Margenthaler, Julie; Wang, Lihong V.

    2014-03-01

    Sentinel lymph node biopsy (SLNB) has emerged as an accurate, less invasive alternative to axillary lymph node dissection, and it has rapidly become the standard of care for patients with clinically node-negative breast cancer. The sentinel lymph node (SLN) hypothesis states that the pathological status of the axilla can be accurately predicted by determining the status of the first (i.e., sentinel) lymph nodes that drain from the primary tumor. Physicians use radio-labeled sulfur colloid and/or methylene blue dye to identify the SLN, which is most likely to contain metastatic cancer cells. However, the surgical procedure causes morbidity and associated expenses. To overcome these limitations, we developed a dual-modality photoacoustic and ultrasound imaging system to noninvasively detect SLNs based on the accumulation of methylene blue dye. Ultimately, we aim to guide percutaneous needle biopsies and provide a minimally invasive method for axillary staging of breast cancer. The system consists of a tunable dye laser pumped by a Nd:YAG laser, a commercial ultrasound imaging system (Philips iU22), and a multichannel data acquisition system which displays co-registered photoacoustic and ultrasound images in real-time. Our clinical results demonstrate that real-time photoacoustic imaging can provide sensitive and specific detection of methylene blue dye in vivo. While preliminary studies have shown that in vivo detection of SLNs by using co-registered photoacoustic and ultrasound imaging is feasible, further investigation is needed to demonstrate robust SLN detection.

  17. Emergency CT brain: preliminary interpretation with a tablet device: image quality and diagnostic performance of the Apple iPad.

    LENUS (Irish Health Repository)

    Mc Laughlin, Patrick

    2012-04-01

    Tablet devices have recently been used in radiological image interpretation because they have a display resolution comparable to desktop LCD monitors. We identified a need to examine tablet display performance prior to their use in preliminary interpretation of radiological images. We compared the spatial and contrast resolution of a commercially available tablet display with a diagnostic grade 2 megapixel monochrome LCD using a contrast detail phantom. We also recorded reporting discrepancies, using the ACR RADPEER system, between preliminary interpretation of 100 emergency CT brain examinations on the tablet display and formal review on a diagnostic LCD. The iPad display performed inferiorly to the diagnostic monochrome display without the ability to zoom. When the software zoom function was enabled on the tablet device, comparable contrast detail phantom scores of 163 vs 165 points were achieved. No reporting discrepancies were encountered during the interpretation of 43 normal examinations and five cases of acute intracranial hemorrhage. There were seven RADPEER2 (understandable) misses when using the iPad display and 12 with the diagnostic LCD. Use of software zoom in the tablet device improved its contrast detail phantom score. The tablet allowed satisfactory identification of acute CT brain findings, but additional research will be required to examine the cause of "understandable" reporting discrepancies that occur when using tablet devices.

  18. [Development of RF coil of permanent magnet mini-magnetic resonance imager and mouse imaging experiments].

    Science.gov (United States)

    Hou, Shulian; Xie, Huantong; Chen, Wei; Wang, Guangxin; Zhao, Qiang; Li, Shiyu

    2014-10-01

    In the development of radio frequency (RF) coils for better quality of the mini-type permanent magnetic resonance imager for using in the small animal imaging, the solenoid RF coil has a special advantage for permanent magnetic system based on analyses of various types.of RF coils. However, it is not satisfied for imaging if the RF coils are directly used. By theoretical analyses of the magnetic field properties produced from the solenoid coil, the research direction was determined by careful studies to raise further the uniformity of the magnetic field coil, receiving coil sensitivity for signals and signal-to-noise ratio (SNR). The method had certain advantages and avoided some shortcomings of the other different coil types, such as, birdcage coil, saddle shaped coil and phased array coil by using the alloy materials (from our own patent). The RF coils were designed, developed and made for keeled applicable to permanent magnet-type magnetic resonance imager, multi-coil combination-type, single-channel overall RF receiving coil, and applied for a patent. Mounted on three instruments (25 mm aperture, with main magnetic field strength of 0.5 T or 1.5 T, and 50 mm aperture, with main magnetic field strength of 0.48 T), we performed experiments with mice, rats, and nude mice bearing tumors. The experimental results indicated that the RF receiving coil was fully applicable to the permanent magnet-type imaging system.

  19. A Preliminary Study on 1D Numerical Experiment of Water Debris Flow in Gully

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    In order to improve and enhance the numerical modeling methods and its application on debris flow problems,a preliminary study has been proposed in accordance with the corrected water-sediment numerical model on the premise of revised resistance and sediment capacity equations.Firstly,an overview the recent re- search achievements on numerical simulation of debris flow has been conducted,the results shown that a gener- al numerical model for debris flow can not be existed at all because the complex rheol...

  20. Rapid screening of wheat bran contaminated by deoxynivalenol mycotoxin using Raman spectroscopy: a preliminary experiment

    Science.gov (United States)

    Mignani, A. G.; Ciaccheri, L.; Mencaglia, A. A.; De Girolamo, A.; Lippolis, V.; Pascale, M.

    2016-05-01

    Deoxynivalenol (DON) is a mycotoxin frequently occurring in cereals and derived products, and regulated in many countries. Raman spectroscopy performed using optical fibers, with excitation at 1064 nm and a dispersive detection scheme, was utilized to analyze wheat bran samples naturally contaminated with DON. A multivariate processing of the spectroscopic data allowed to distinguish two classes of contamination, with DON below and above 400 μg/kg, respectively. Only one highly contaminated sample was misclassified. This preliminary result demonstrates the potential of Raman spectroscopy as a useful analytical tool for the non-destructive and rapid analysis of mycotoxins in food.

  1. Frictional sliding in layered rock model: Preliminary experiments. Yucca Mountain Site Characterization Project

    Energy Technology Data Exchange (ETDEWEB)

    Perry, K.E. Jr.; Buescher, B.J.; Anderson, D.; Epstein, J.S. [Idaho National Engineering Lab., Idaho Falls, ID (United States)

    1995-09-01

    An important aspect of determining the suitability of Yucca Mountain as a possible nuclear waste repository requires understanding the mechanical behavior of jointed rock-masses. To this end we have studied the frictional sliding between simulated rock joints in the laboratory using the technique of phase shifting moire interferometry. The models were made from stacks of Lexan plates and contained a central hole to induce slip between the plates when the models were loaded in compression. These preliminary results confirm the feasibility of the approach and show a clear evolution of slip as function of load.

  2. Mass transport phenomena in microgravity: Preliminary results of the first MEPHISTO flight experiment

    Science.gov (United States)

    Favier, Jean Jacques; Garandet, J. P.; Rouzaud, A.; Camel, D.

    1994-01-01

    The MEPHISTO space program is the result of a cooperative effort that involves the French nuclear and space agencies (Commissariat a l'energie atomique, CEA - Centre National d'Etudes Spatiales, CNES) and the American National Aeronautics and Space Administration (NASA). The scientific studies and apparatus development were funded in the frame of the GRAMME agreement between CEA and CNES, the flight costs being taken in charge by NASA. Six flight opportunities are scheduled, with alternating French and American principal investigators. It is the purpose of this paper to briefly present MEPHISTO along with the preliminary results obtained during its first flight on USMP-1 in October 1992.

  3. Preliminary Single-Center Canadian Experience of Human Normothermic Ex Vivo Liver Perfusion: Results of a Clinical Trial.

    Science.gov (United States)

    Bral, M; Gala-Lopez, B; Bigam, D; Kneteman, N; Malcolm, A; Livingstone, S; Andres, A; Emamaullee, J; Russell, L; Coussios, C; West, L J; Friend, P J; Shapiro, A M J

    2017-04-01

    After extensive experimentation, outcomes of a first clinical normothermic machine perfusion (NMP) liver trial in the United Kingdom demonstrated feasibility and clear safety, with improved liver function compared with standard static cold storage (SCS). We present a preliminary single-center North American experience using identical NMP technology. Ten donor liver grafts were procured, four (40%) from donation after circulatory death (DCD), of which nine were transplanted. One liver did not proceed because of a technical failure with portal cannulation and was discarded. Transplanted NMP grafts were matched 1:3 with transplanted SCS livers. Median NMP was 11.5 h (range 3.3-22.5 h) with one DCD liver perfused for 22.5 h. All transplanted livers functioned, and serum transaminases, bilirubin, international normalized ratio, and lactate levels corrected in NMP recipients similarly to controls. Graft survival at 30 days (primary outcome) was not statistically different between groups on an intent-to-treat basis (p = 0.25). Intensive care and hospital stays were significantly more prolonged in the NMP group. This preliminary experience demonstrates feasibility as well as potential technical risks of NMP in a North American setting and highlights a need for larger, randomized studies. © 2016 The American Society of Transplantation and the American Society of Transplant Surgeons.

  4. TESIS experiment on EUV imaging spectroscopy of the Sun

    Science.gov (United States)

    Kuzin, S. V.; Bogachev, S. A.; Zhitnik, I. A.; Pertsov, A. A.; Ignatiev, A. P.; Mitrofanov, A. M.; Slemzin, V. A.; Shestov, S. V.; Sukhodrev, N. K.; Bugaenko, O. I.

    2009-03-01

    TESIS is a set of solar imaging instruments in development by the Lebedev Physical Institute of the Russian Academy of Science, to be launched aboard the Russian spacecraft CORONAS-PHOTON in December 2008. The main goal of TESIS is to provide complex observations of solar active phenomena from the transition region to the inner and outer solar corona with high spatial, spectral and temporal resolution in the EUV and Soft X-ray spectral bands. TESIS includes five unique space instruments: the MgXII Imaging Spectroheliometer (MISH) with spherical bent crystal mirror, for observations of the Sun in the monochromatic MgXII 8.42 Å line; the EUV Spectoheliometer (EUSH) with grazing incidence difraction grating, for the registration of the full solar disc in monochromatic lines of the spectral band 280-330 Å; two Full-disk EUV Telescopes (FET) with multilayer mirrors covering the band 130-136 and 290-320 Å; and the Solar EUV Coronagraph (SEC), based on the Ritchey-Chretien scheme, to observe the inner and outer solar corona from 0.2 to 4 solar radii in spectral band 290-320 Å. TESIS experiment will start at the rising phase of the 24th cycle of solar activity. With the advanced capabilities of its instruments, TESIS will help better understand the physics of solar flares and high-energy phenomena and provide new data on parameters of solar plasma in the temperature range 10-10K. This paper gives a brief description of the experiment, its equipment, and its scientific objectives.

  5. The Dysarthria Impact Profile: A Preliminary French Experience with Parkinson’s Disease

    Directory of Open Access Journals (Sweden)

    Alban Letanneux

    2013-01-01

    Full Text Available This preliminary study aimed to adapt the Dysarthria Impact Profile (DIP in French and to confirm its relevance for the assessment of the psychosocial impact of dysarthria in Parkinson's disease (PD. The DIP scale was administered to 10 people with PD and 10 age-matched control subjects. The DIP psychometric properties were calculated (discriminant validity, internal consistency, and concurrent validity, notably by using the Voice Handicap Index (VHI for interscale comparisons. The French version of the DIP discriminated people with PD from control subjects (χ2 test, P<0.05. Good internal consistency was observed in both populations (Cronbach’s α=0.93 for PD people and α=0.76 for control subjects. The DIP was highly correlated with the VHI (Spearman’s ρ=-0.70, P<0.01, confirming the external validity of the scale. There was no direct relationship between PD speech and quality of life as assessed by the Parkinson’s Disease Questionnaire-39 (PDQ-39. Our preliminary data suggest that the French version of the DIP has the potential to make a useful contribution for the assessment and outcome management in acquired dysarthria for both clinicians and researchers.

  6. Preliminary experience of fractionated stereotactic radiosurgery with extend system of Gamma Knife

    Directory of Open Access Journals (Sweden)

    Raj Bisht

    2016-03-01

    Full Text Available Purpose: The purpose of this study is to present multisession stereotactic radiosurgery with initial experience using custom made extend system (ES of Gamma Knife.Methods: The ES is comprised of a carbon fiber frame also called extend frame, vacuum head rest cushion, patient surveillance unit and a configurable front piece with dental impression tray. The extend frame is a rigid connection between patient's head and patient positioning system (PPS of Gamma Knife. A dental impression of patient was created and attached to the frontal piece of extend system. The treatment setup involves positioning the patient within the extend frame using patient specific headrest cushion and front piece. The reference patient’s head position was recorded through measurements of repositioning check tool (RCT apertures using a high precision digital probe before computed tomography (CT scan. The RCT measurements taken before treatment were compared with recorded reference position to ensure appropriate patient treatment position. Volumetric magnetic resonance (MR scan was co-registered with stereotactic CT scan on Leksell Gamma plan. Fused MR to CT images on Gamma Plan was utilized to delineate regions of interest and prepare a precise treatment plan. The presented study includes positional reproducibility check and dosimetric evaluation of ten patients treated with ES.Results: Forty-three fractions on ten patients with prescribed treatment format were delivered successfully. An average tumor volume of 11.26 cm3 (range, 340 mm3 to 59.12 cm3 was treated with ES. The mean tumor coverage of 91.91% (range, 90% to 95% was able to achieve at 50% prescription isodose without compromising adjacent normal structure radiation dose tolerances. The mean inter-fraction positional variation of 0.69 mm influences an inherent strength of immobilization technique. Follow-up of seven patients at a median interval of 16 months (range, 9 months to 26 months showed evidence of 100

  7. Three-dimensional image registration as a tool for forensic odontology: a preliminary investigation.

    Science.gov (United States)

    Abduo, Jaafar; Bennamoun, Mohammed

    2013-09-01

    Frequently, human dentition is utilized for victim identification. This report introduces a new human identification technique based on the principle of 3-dimensional (3D) image registration of the dentition. With the aid of a dry human skull, postmortem (PM) and antemortem (AM) scenarios were assumed. The skull in its initial state composed the PM scenario. Virtual 3D PM images were reconstructed from medical CT images. The AM scenario was achieved by reconstructing the missing hard and soft tissues of the skull by dental waxes. Virtual 3D AM images were obtained by laser surface scanning. The virtual PM and AM images were registered at 2 levels: arch level and tooth level. At arch level, the deviation between the 2 images was 0.147 mm for the maxilla and 0.166 mm for the mandible. At tooth level, the deviation average ranged from 0.077 to 0.237 mm. Qualitatively, even image fit was observed for the arches, intact teeth, and teeth with minimal deficiencies. As the tooth defect increased, the alignment discrepancy increased. It is concluded that 3D image registration ensured an accurate superimposition of the 3D images and can be used as a robust tool for forensic identification.

  8. A preliminary investigation of communication techniques for local and remote access to image databases

    Science.gov (United States)

    Ma, Mathias; Danielson, Ronald L.; Likens, William C.

    1988-01-01

    A software technique which allows users to examine images remotely while minimizing transmission time, is discussed. The technique provides a browsing capability, making it possible to roam over larger images, to zoom to various resolution levels, and to specify subregions of interest in the image to display at full resolution. The software permits analysts to remotely submit images for processing and to review the processing result. The capabilities of the technique under varying conditions and the speed at which imagery can be displayed over direct connect serial lines are discussed and examples of the imagery at various levels of resolution are presented.

  9. Development of ring imaging Cherenkov detectors for the LHCb experiment

    CERN Document Server

    John, M J J

    2001-01-01

    This thesis reports on work done as part of the development of the Ring Imaging Cherenkov (RICH) detectors of the LHCb experiment. The context of this work is set out in Chapter 1, which includes an overview of the physics of CP violation, followed by a discussion of other experiments that study B physics. LHCb itself is then described, with particular emphasis on its RICH detectors, and the photon detectors to be used therein. The work done by the author to ensure an adequate shielding of the photon detectors in the two RICH detectors from the magnetic fields produced by the LHCb dipole is then presented. A candidate photodetector for the RICH is the Pixel HPD. The author's contribution to the upgrade of the HPD test system to operate at the LHC bunch-crossing rate of 40MHz is the subject of the following section. This system was used to investigate and optimise a method of minimising the threshold distribution of the Pixel HPD's encapsulated readout chip. The final chapter of the thesis concerns the aerogel...

  10. Development of an Image Processing System for Automatic Melanoma Diagnosis from Dermoscopic Images: Preliminary Sudy - Original Article

    Directory of Open Access Journals (Sweden)

    M. Emin Yüksel

    2008-12-01

    Full Text Available Objective: Design and implementation of a medical image processing system that will provide decision support to the clinician in the diagnosis of melanoma type skin cancers by performing the analysis of dermoscopic images.Methods: Visual features of pigmented lesions are converted into measurable numerical quantities by employing digital image processing methods and a classification regarding melanoma diagnosis is performed based on these quantitative data.Results: We achieved numerical results showing asymmetry, border and color features of the pigmentary lesions by using segmentation, image histogram, thresholding, convex hull, color clustering, color quantization and distribution methods. Conclusion: The system under development speeds up the decision process of the clinician. In addition, it allows the diagnosis to be based on more objective data.

  11. A preliminary investigation of the environmental Control and Life Support Subsystems (EC/LSS) for animal and plant experiment payloads

    Science.gov (United States)

    Wells, H. B.

    1972-01-01

    A preliminary study of the environmental control and life support subsystems (EC/LSS) necessary for an earth orbital spacecraft to conduct biological experiments is presented. The primary spacecraft models available for conducting these biological experiments are the space shuttle and modular space station. The experiments would be housed in a separate module that would be contained in either the shuttle payload bay or attached to the modular space station. This module would be manned only for experiment-related tasks, and would contain a separate EC/LSS for the crew and animals. Metabolic data were tabulated on various animals that are considered useful for a typical experiment program. The minimum payload for the 30-day space shuttle module was found to require about the equivalent of a one-man EC/LSS; however, the selected two-man shuttle assemblies will give a growth and contingency factor of about 50 percent. The maximum payloads for the space station mission will require at least a seven-man EC/LSS for the laboratory colony and a nine-man EC/LSS for the centrifuge colony. There is practically no room for growth or contingencies in these areas.

  12. Flexible Fiber-Optic High-Speed Imaging of Vocal Fold Vibration: A Preliminary Report.

    Science.gov (United States)

    Woo, Peak; Baxter, Peter

    2017-03-01

    High-speed video (HSV) imaging of vocal fold vibration has been possible only through the rigid endoscope. This study reports that a fiberscope-based high-speed imaging system may allow HSV imaging of naturalistic voicing. Twenty-two subjects were recorded using a commercially available black and white high-speed camera (Photron Motion Tools, 256 × 120 pixel, 2000 frames per second, 8 second acquisition time). The camera gain is set to +6 db. The camera is coupled to a standard fiber-optic laryngoscope (Olympus ENF P-4) with a 300-W Xenon light. Image acquisition was done by asking the subject to perform repeated phonation at modal phonation. Video images were processed using commercial video editing and video noise reduction software (After effects, Magix, and Neat Video 4.1). After video processing, the video images were analyzed using digital kymography (DKG). The HSV black and white video acquired by the camera is gray and lacks contrast. By adjustment of image contrast, brightness, and gamma and using noise reduction software, the flexible laryngoscopy image can be converted to video image files suitable for DKG and waveform analysis. The increased noise still makes edge tracking for objective analysis difficult, but subjective analysis of DKG plot is possible. This is the first report of HSV acquisition in an unsedated patient using a fiberscope. Image enhancement and noise reduction can enhance the HSV to allow extraction of the digital kymogram. Further image enhancement may allow for objective analysis of the vibratory waveform. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  13. Two-photon deep imaging through skin and skull of Zebra finches: preliminary studies for in-vivo brain metabolism monitoring

    Science.gov (United States)

    Abi-Haidar, D.; Olivier, T.; Mottin, S.; Vignal, C.; Mathevon, N.

    2007-02-01

    Zebra Finches are songbirds which constitute a model for neuro-ethologists to study the neuro-mechanisms of vocal recognition. For this purpose, in vivo and non invasive monitoring of brain activity is required during acoustical stimulation. MRI (Magnetic Resonance Imaging) or NIRS (Near InfraRed Spectroscopy) are suitable methods for these measurements, even though MRI is difficult to link quantitatively with neural activity and NIRS suffers from a poor resolution. In the particular case of songbirds (whose skin is thin and quite transparent and whose skull structure is hollow), two-photon microscopy enables a quite deep penetration in tissues and could be an alternative. We present here preliminary studies on the feasability of two-photon microscopy in these conditions. To do so, we chose to image hollow fibers, filled with Rhodamine B, through the skin of Zebra finches in order to evaluate the spatial resolution we may expect in future in vivo experiments. Moreover, we used the reflectance-mode confocal configuration to evaluate the exponential decrease of backreflected light in skin and in skull samples. Following this procedure recently proposed by S.L. Jacques and co-workers, we planned to determine the scattering coefficient μ s and the anisotropy g of these tissues and make a comparison between fixed and fresh skin and skull samples for future Monte Carlo simulations of the scattering in our particular multi-layered structure.

  14. Preliminary Observations on Sensitivity and Specificity of Magnetization Transfer Asymmetry for Imaging Myelin of Rat Brain at High Field.

    Science.gov (United States)

    Kim, Jae-Woong; Choi, Jiye; Cho, Janggeun; Lee, Chulhyun; Jeon, Daejong; Park, Sung-Hong

    2015-01-01

    Magnetization transfer ratio (MTR) has been often used for imaging myelination. Despite its high sensitivity, the specificity of MTR to myelination is not high because tissues with no myelin such as muscle can also show high MTR. In this study, we propose a new magnetization transfer (MT) indicator, MT asymmetry (MTA), as a new method of myelin imaging. The experiments were performed on rat brain at 9.4 T. MTA revealed high signals in white matter and significantly low signals in gray matter and muscle, indicating that MTA has higher specificity than MTR. Demyelination and remyelination studies demonstrated that the sensitivity of MTA to myelination was as high as that of MTR. These experimental results indicate that MTA can be a good biomarker for imaging myelination. In addition, MTA images can be efficiently acquired with an interslice MTA method, which may accelerate clinical application of myelin imaging.

  15. Frictional sliding in layered rock: Preliminary experiments on stacked Lexan plates

    Energy Technology Data Exchange (ETDEWEB)

    Perry, K.E. Jr.; Epstein, J.S. [Idaho National Engineering Laboratory, Idaho Falls, ID (United States). Fracture Behavior Group; Jung, J. [Sandia National Labs., Albuquerque, NM (United States)

    1995-12-31

    Understanding the mechanical behavior of jointed-rock masses is of critical importance to designing and predicting the performance of a potential nuclear waste repositiry. To this end we have studied the frictional sliding between simulated rock joints using phase shifting moire interferometry. Preliminary calibration models were made from stacks of Lexan plates that were sand-blasted to provide a uniform frictional interface. Load was applied monotonically and phase shifted moire fringe patterns were recorded at three different load states. Plots of slip along the interfaces for the model are presented to demonstrate the ability of the photomechanics technique to provide precise measurements of in-plane displacement, and ultimately the slip between the plates.

  16. Image of Women in Advertisements: A Preliminary Study of Avenues for Change.

    Science.gov (United States)

    Butler-Paisley, Matilda, Ed.; And Others

    The Center for Research on Women (CROW) at Stanford University along with the Communication Department, the Psychology Department, and the School of Education conducted a study on the image of women in advertising and suggested ways to improve women's image in the advertising media. With the objective of sponsoring some alternatives to expedite…

  17. Soil transference patterns on bras: Image processing and laboratory dragging experiments.

    Science.gov (United States)

    Murray, Kathleen R; Fitzpatrick, Robert W; Bottrill, Ralph S; Berry, Ron; Kobus, Hilton

    2016-01-01

    In a recent Australian homicide, trace soil on the victim's clothing suggested she was initially attacked in her front yard and not the park where her body was buried. However the important issue that emerged during the trial was how soil was transferred to her clothing. This became the catalyst for designing a range of soil transference experiments (STEs) to study, recognise and classify soil patterns transferred onto fabric when a body is dragged across a soil surface. Soil deposits of interest in this murder were on the victim's bra and this paper reports the results of anthropogenic soil transfer to bra-cups and straps caused by dragging. Transfer patterns were recorded by digital photography and photomicroscopy. Eight soil transfer patterns on fabric, specific to dragging as the transfer method, appeared consistently throughout the STEs. The distinctive soil patterns were largely dependent on a wide range of soil features that were measured and identified for each soil tested using X-ray Diffraction and Non-Dispersive Infra-Red analysis. Digital photographs of soil transfer patterns on fabric were analysed using image processing software to provide a soil object-oriented classification of all soil objects with a diameter of 2 pixels and above transferred. Although soil transfer patterns were easily identifiable by naked-eye alone, image processing software provided objective numerical data to support this traditional (but subjective) interpretation. Image software soil colour analysis assigned a range of Munsell colours to identify and compare trace soil on fabric to other trace soil evidence from the same location; without requiring a spectrophotometer. Trace soil from the same location was identified by linking soils with similar dominant and sub-dominant Munsell colour peaks. Image processing numerical data on the quantity of soil transferred to fabric, enabled a relationship to be discovered between soil type, clay mineralogy (smectite), particle size and

  18. Multifrequency radar imaging of ash plumes: an experiment at Stromboli

    Science.gov (United States)

    Donnadieu, Franck; Freret-Lorgeril, Valentin; Delanoë, Julien; Vinson, Jean-Paul; Peyrin, Frédéric; Hervier, Claude; Caudoux, Christophe; Van Baelen, Joël; Latchimy, Thierry

    2016-04-01

    Volcanic ash emissions in the atmosphere are hazardous to aviation while ash fallout affects people and human activities and may cause damage to infrastructures and economic losses. In the framework of the French Government Laboratory of Excellence ClerVolc initiative, an experiment was carried out on Stromboli volcano (Italy), between 28 September and 4 October 2015. The aim was to retrieve various physical properties of the ash plumes, especially the mass loading parameters which are critical for the modelling of ash dispersal. We used a complementary set of cutting edge techniques recording in different bands of the electromagnetic spectrum. The innovative instrument setup consisted in three radars, hyperspectral thermal infrared and dual-band UV cameras, a mini DOAS-Flyspec and a multigas sensor. A drone equipped with differential GPS was flown near the ash plumes with several sensors including SO2, CO2 and particle counter. We mainly focus on radar measurements of over 200 ash plumes and present some preliminary comparisons at three frequencies. The BASTA Doppler radar at 95 GHz, originally designed for atmospheric studies, was deployed at about 2.2 km in slant distance from the eruptive craters. It was configured to observe volumes above one of the active craters with a spatio-temporal resolution of 12.5 m and 1 s. From the same location, a 1.2 GHz volcano Doppler radar (VOLDORAD) was recording the signature of ballistics and small lapilli at 0.15 s in 60 m-deep volumes. In addition, a commercial 24 GHz micro rain Doppler radar (MRR) simultaneously recorded activity from the Rochette station, at 400 to 650 m from the active craters with a sampling rate of 10 s and a resolution of 25 m. The latter was pointing almost perpendicularly to the other radar beams. Reflectivity factors were measured inside the ash plume above the source vent by the BASTA radar (3 mm wavelength) spanning -9 to +21 dBZ. Fallout could sometimes be tracked during several minutes within

  19. A preliminary study of CT imaging of water in a carnation flower

    Energy Technology Data Exchange (ETDEWEB)

    Nakanishi, T.M. [Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113 (Japan); Furukawa, J. [Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113 (Japan); Matsubayashi, M. [Japan Atomic Energy Research Institute, Tokai-mura, Naka-gun, Ibaraki-ken 319-11 (Japan)

    1999-11-03

    We present the trial to determine the water deletion part in a carnation flower tissue while drying by neutron computer tomography (CT). The flower part was fixed on a rotating disk and thermal neutrons were irradiated for 4 s per projection. The total neutron dose was 6.0x10{sup 8} n/cm{sup 2} per projection. The neutrons penetrating the sample were converted to photons by a fluorescence converter. The photon image was guided to a cooled CCD camera using two mirrors. The sample was rotated, stepwise, every 1 deg. , up to 180 deg. , i.e. 180 images were obtained for the CT construction. Horizontal CT images of several slices of the flower were taken before and after the drying treatment. Vertical CT images of the flower were also constructed based on horizontal CT images. It was found that the water around the ovule was selectively removed by the drying treatment.

  20. A preliminary study of CT imaging of water in a carnation flower

    Science.gov (United States)

    Nakanishi, T. M.; Furukawa, J.; Matsubayashi, M.

    1999-11-01

    We present the trial to determine the water deletion part in a carnation flower tissue while drying by neutron computer tomography (CT). The flower part was fixed on a rotating disk and thermal neutrons were irradiated for 4 s per projection. The total neutron dose was 6.0×10 8 n/cm 2 per projection. The neutrons penetrating the sample were converted to photons by a fluorescence converter. The photon image was guided to a cooled CCD camera using two mirrors. The sample was rotated, stepwise, every 1°, up to 180°, i.e. 180 images were obtained for the CT construction. Horizontal CT images of several slices of the flower were taken before and after the drying treatment. Vertical CT images of the flower were also constructed based on horizontal CT images. It was found that the water around the ovule was selectively removed by the drying treatment.

  1. Preliminary study of synthetic aperture tissue harmonic imaging on in-vivo data

    DEFF Research Database (Denmark)

    Rasmussen, Joachim Hee; Hemmsen, Martin Christian; Sloth Madsen, Signe

    2013-01-01

    A method for synthetic aperture tissue harmonic imaging is investigated. It combines synthetic aperture sequential beamforming (SASB) with tissue harmonic imaging (THI) to produce an increased and more uniform spatial resolution and improved side lobe reduction compared to conventional B......-mode imaging. Synthetic aperture sequential beamforming tissue harmonic imaging (SASB-THI) was implemented on a commercially available BK 2202 Pro Focus UltraView ultrasound system and compared to dynamic receive focused tissue harmonic imaging (DRF-THI) in clinical scans. The scan sequence...... that was implemented on the UltraView system acquires both SASB-THI and DRF-THI simultaneously. Twenty-four simultaneously acquired video sequences of in-vivo abdominal SASB-THI and DRF-THI scans on 3 volunteers of 4 different sections of liver and kidney tissues were created. Videos of the in-vivo scans were...

  2. Preliminary Application of High-Definition CT Gemstone Spectral Imaging in Hand and Foot Tendons

    Energy Technology Data Exchange (ETDEWEB)

    Deng, Kai; Zhang, Cheng Qi; Li, Wei; Wang, Xin Yi; Pang, Tao Peng; Wang, Guang Li [Dept. of Medical Imaging, Qianfoshan Hospital Affiliated to Shandong University, Jinan (China); Wang, Jun Jun [The Medical College of Shandong University, Jinan (China); Lui, Cheng [CT Room, Shandong Medical Imaging Research Institute, Jinan (China)

    2012-11-15

    To assess the feasibility of visualizing hand and foot tendon anatomy and disorders by Gemstone Spectral Imaging (GSI) high-definition CT (HDCT). Thirty-five patients who suffered from hand or foot pain were scanned with GSI mode HDCT and MRI. Spectrum analysis was used to select the monochromatic images that provide the optimal contrast-to-noise ratio (CNR) for tendons. The image quality at the best selected monochromatic level and the conventional polychromatic images were compared. Tendon anatomy and disease were also analyzed at GSI and MRI. The monochromatic images at about 65 keV (mean 65.09 {+-} 2.98) provided the optimal CNR for hand and foot tendons. The image quality at the optimal selected monochromatic level was superior to conventional polychromatic images (p = 0.005, p < 0.05). GSI was useful in visualizing hand and foot tendon anatomy and disorders. There were no statistical differences between GSI and MRI with regard to tendon thickening (X{sup 2} = 0, p > 0.05), compression (X{sup 2} = 0.5, p > 0.05), absence (X{sup 2} = 0, p > 0.05) and rupture (X{sup 2} = 0, p > 0.05). GSI was significantly less sensitive than MRI in displaying tendon adhesion (X{sup 2} = 4.17, p < 0.05), degeneration (X{sup 2} = 4.17, p < 0.05), and tendinous sheath disease (X{sup 2} = 10.08, p < 0.05). GSI with monochromatic images at 65 keV displays clearly the most hand and foot tendon anatomy and disorders with image quality improved, as compared with conventional polychromatic images. It may be used solely or combined with MRI in clinical work, depending on individual patient disease condition.

  3. A preliminary study for fully automated quantification of psoriasis severity using image mapping

    Science.gov (United States)

    Mukai, Kazuhiro; Iyatomi, Hitoshi

    2014-03-01

    Psoriasis is a common chronic skin disease and it detracts patients' QoL seriously. Since there is no known permanent cure so far, controlling appropriate disease condition is necessary and therefore quantification of its severity is important. In clinical, psoriasis area and severity index (PASI) is commonly used for abovementioned purpose, however it is often subjective and troublesome. A fully automatic computer-assisted area and severity index (CASI) was proposed to make an objective quantification of skin disease. It investigates the size and density of erythema based on digital image analysis, however it does not consider various inadequate effects caused by different geometrical conditions under clinical follow-up (i.e. variability in direction and distance between camera and patient). In this study, we proposed an image alignment method for clinical images and investigated to quantify the severity of psoriasis under clinical follow-up combined with the idea of CASI. The proposed method finds geometrical same points in patient's body (ROI) between images with Scale Invariant Feature Transform (SIFT) and performs the Affine transform to map the pixel value to the other. In this study, clinical images from 7 patients with psoriasis lesions on their trunk under clinical follow-up were used. In each series, our image alignment algorithm align images to the geometry of their first image. Our proposed method aligned images appropriately on visual assessment and confirmed that psoriasis areas were properly extracted using the approach of CASI. Although we cannot evaluate PASI and CASI directly due to their different definition of ROI, we confirmed that there is a large correlation between those scores with our image quantification method.

  4. Preliminaries on core image analysis using fault drilling samples; Core image kaiseki kotohajime (danso kussaku core kaisekirei)

    Energy Technology Data Exchange (ETDEWEB)

    Miyazaki, T.; Ito, H. [Geological Survey of Japan, Tsukuba (Japan)

    1996-05-01

    This paper introduces examples of image data analysis on fault drilling samples. The paper describes the following matters: core samples used in the analysis are those obtained from wells drilled piercing the Nojima fault which has moved in the Hygoken-Nanbu Earthquake; the CORESCAN system made by DMT Corporation, Germany, used in acquiring the image data consists of a CCD camera, a light source and core rotation mechanism, and a personal computer, its resolution being about 5 pixels/mm in both axial and circumferential directions, and 24-bit full color; with respect to the opening fractures in core samples collected by using a constant azimuth coring, it was possible to derive values of the opening width, inclination angle, and travel from the image data by using a commercially available software for the personal computer; and comparison of this core image with the BHTV record and the hydrophone VSP record (travel and inclination obtained from the BHTV record agree well with those obtained from the core image). 4 refs., 4 figs.

  5. The Sun Radio Imaging Space Experiment (SunRISE) Mission

    Science.gov (United States)

    Lazio, Joseph; Kasper, Justin; Maksimovic, Milan; Alibay, Farah; Amiri, Nikta; Bastian, Tim; Cohen, Christina; Landi, Enrico; Manchester, Ward; Reinard, Alysha; Schwadron, Nathan; Cecconi, Baptiste; Hallinan, Gregg; Hegedus, Alex; Krupar, Vratislav; Zaslavsky, Arnaud

    2017-04-01

    Radio emission from coronal mass ejections (CMEs) is a direct tracer of particle acceleration in the inner heliosphere and potential magnetic connections from the lower solar corona to the larger heliosphere. Energized electrons excite Langmuir waves, which then convert into intense radio emission at the local plasma frequency, with the most intense acceleration thought to occur within 20 RS. The radio emission from CMEs is quite strong such that only a relatively small number of antennas is required to detect and map it, but many aspects of this particle acceleration and transport remain poorly constrained. Ground-based arrays would be quite capable of tracking the radio emission associated with CMEs, but absorption by the Earth's ionosphere limits the frequency coverage of ground-based arrays (ν ≳ 15 MHz), which in turn limits the range of solar distances over which they can track the radio emission (≲ 3RS). The state-of-the-art for tracking such emission from space is defined by single antennas (Wind/WAVES, Stereo/SWAVES), in which the tracking is accomplished by assuming a frequency-to-density mapping; there has been some success in triangulating the emission between the spacecraft, but considerable uncertainties remain. We describe the Sun Radio Imaging Space Experiment (SunRISE) mission concept: A constellation of small spacecraft in a geostationary graveyard orbit designed to localize and track radio emissions in the inner heliosphere. Each spacecraft would carry a receiving system for observations below 25 MHz, and SunRISE would produce the first images of CMEs more than a few solar radii from the Sun. Part of this research was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration.

  6. Value or waste: Perfusion imaging following radiofrequency ablation - early experience.

    Science.gov (United States)

    Thieme, Stefan F; Vahldiek, Janis L; Tummler, Katja; Poch, Franz; Gemeinhardt, Ole; Hiebl, Bernhard; Lehmann, Kai S; Hamm, B; Niehues, Stefan M

    2015-01-01

    Radiofrequency ablation (RFA) is an evolving technique in treatment of hepatic malignant tumors. By heating local tissue it leads to coagulative necrotic areas around the ablation probe. Temperature falls with increasing distance to the probe, risking incomplete necrosis at the margins of the RFA-induced lesion. Therefore, immediate non-invasive and precise detection of incomplete ablation is necessary for early enlargement of the ablation if needed. This in vivo pig study compares early experiences of immediate post-interventional computed tomography (CT) perfusion volume analysis to macroscopic and CT image evaluation in healthy pig liver. RFA was performed in vivo in healthy pig livers. Different CT perfusion algorithms (Maximum slope analysis and Patlak plot) were used to quantify three different perfusion parameters. Data points were acquired from rectangular grids. These grids were semiautomatically overlayed to macroscopic images documented after liver explantation. Each data point was visually assigned to zones defined as "inner" and "outer necrotic zone", "margin" or "vital tissue". Significant differences between necrotic zones and vital tissue are shown for equivalent blood volume (p <  0.0001), arterial flow (p <  0.01) and flow extraction product (p <  0.001). Looking at equivalent blood volume and flow extraction product, there were also significant differences (EquivBV: p <  0.0001, FE: p <  0.001) between margins, necrotic and vital areas. In a porcine model these early results could show that all of the used CT perfusion parameters allowed discrimination of necrosis from vital tissue after RFA at high levels of significance. In addition, the parameters EquivBV and FE that give an estimate of the tissue blood volume and the permeability, were able to precisely discern different zones also seen macroscopically. From this data CT perfusion analysis could be precise tool for measurement and visualization of ablated liver lesions and

  7. Aid in the detection of myocardial perfusion abnormality utilizing SPECT atlas and images registration: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Padua, Rodrigo Donizete Santana de [Universidade de Sao Paulo (USP), Ribeirao Preto, SP (Brazil). Faculdade de Medicina. Div. de Cardiologia]. E-mail: rodrigo_dsp@hcrp.fmrp.usp.br; Oliveira, Lucas Ferrari de [Universidade Federal de Pelotas (UFPel), RS (Brazil). Inst. de Fisica e Matematica. Dept. de Tecnologia da Informacao; Marques, Paulo Mazzoncini de Azevedo [Universidade de Sao Paulo (USP), Ribeirao Preto, SP (Brazil). Faculdade de Medicina. Centro de Ciencias das Imagens e Fisica Medica; Groote, Jean-Jacques Georges Soares de [Instituto de Ensino Superior COC, Ribeirao Preto, SP (Brazil). Lab. of Artifical Intelligence and Applications; Castro, Adelson Antonio de [Universidade de Sao Paulo (USP), Ribeirao Preto, SP, (Brazil). Faculdade de Medicina; Ana, Lauro Wichert [Universidade de Sao Paulo (USP), Ribeirao Preto, SP (Brazil). Faculdade de Medicina. Centro de Ciencias das Imagens e Fisica Medica; Simoes, Marcus Vinicius [Universidade de Sao Paulo (USP), Ribeirao Preto, SP, (Brazil). Faculdade de Medicina. Divisao de Cardiologia

    2008-11-15

    To develop an atlas of myocardial perfusion scintigraphy and evaluating its applicability in computer-aided detection of myocardial perfusion defects in patients with ischemic heart disease. The atlas was created with rest-stress myocardial perfusion scintigraphic images of 20 patients of both genders with low probability of coronary artery disease and considered as normal by two experienced observers. Techniques of image registration and mathematical operations on images were utilized for obtaining template images depicting mean myocardial uptake and standard deviation for each gender and physiological condition. Myocardial perfusion scintigraphy images of one male and one female patient were aligned with the corresponding atlas template image, and voxels with myocardial uptake rates two standard deviations below the mean voxel value of the respective region in the atlas template image were highlighted on the tomographic sections and confirmed as perfusion defects by both observe. The present study demonstrated the creation of an atlas of myocardial perfusion scintigraphy with promising results of this tool as an aid in the detection of myocardial perfusion defects. However, further prospective validation with a more representative sample is recommended. (author)

  8. Student Participation in Ecological Research: Preliminary Insights from Students' Experiences in the Smoky Mountains

    Science.gov (United States)

    Pacifici, Lara B.; Miller, Craig; Thomson, Norman

    2009-01-01

    Students participating in summer research internships at the Great Smoky Mountain National Park kept electronic journals to document their experiences. We used a combined content analysis to quantify the responses from the students in particular areas of interest and to understand the essence of experiences from the explanations provided in their…

  9. Near-Death Experiences and the "Fantasy-Prone" Personality: Preliminary Findings.

    Science.gov (United States)

    Council, James R.; Greyson, Bruce

    Near-death experiences (NDEs) are subjective experiences at the threshold of death which can include strong positive affect, dissociation from the physical body, and paranormal/transcendental phenomena. Empirical investigation of NDEs has typically relied upon retrospective reports and personality studies of individuals who have come close to…

  10. Patient Perceptions of Participating in the RSNA Image Share Project: a Preliminary Study.

    Science.gov (United States)

    Hiremath, Atheeth; Awan, Omer; Mendelson, David; Siegel, Eliot L

    2016-04-01

    The purpose of this study was to gauge patient perceptions of the RSNA Image Share Project (ISP), a pilot program that provides patients access to their imaging studies online via secure Personal Health Record (PHR) accounts. Two separate Institutional Review Board exempted surveys were distributed to patients depending on whether they decided to enroll or opt out of enrollment in the ISP. For patients that enrolled, a survey gauged baseline computer usage, perceptions of online access to images through the ISP, effect of patient access to images on patient-physician relationships, and interest in alternative use of images. The other survey documented the age and reasons for declining participation for those that opted out of enrolling in the ISP. Out of 564 patients, 470 enrolled in the ISP (83 % participation rate) and 456 of these 470 individuals completed the survey for a survey participation rate of 97 %. Patients who enrolled overwhelmingly perceived access to online images as beneficial and felt it bolstered their patient-physician relationship. Out of 564 patients, 94 declined enrollment in the ISP and all 94 individuals completed the survey for a survey participation rate of 100 %. Patients who declined to participate in the ISP cited unreliable access to Internet and existing availability of non-web-based intra-network images to their physicians. Patients who participated in the ISP found having a measure of control over their images to be beneficial and felt that patient-physician relationships could be negatively affected by challenges related to image accessibility.

  11. Preliminary Experience Using Dynamic MRI at 3.0 Tesla for Evaluation of Soft Tissue Tumors

    OpenAIRE

    2012-01-01

    Objective We aimed to evaluate the use of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) at 3.0 T for differentiating the benign from malignant soft tissue tumors. Also we aimed to assess whether the shorter length of DCE-MRI protocols are adequate, and to evaluate the effect of temporal resolution. Materials and Methods Dynamic contrast-enhanced magnetic resonance imaging, at 3.0 T with a 1 second temporal resolution in 13 patients with pathologically confirmed soft tissue tu...

  12. Intracranial Dual-Mode IVUS and Hyperthermia Using Circular Arrays: Preliminary Experiments

    OpenAIRE

    Patel, Vivek; Light, Edward; Herickhoff, Carl; Grant, Gerald; Britz, Gavin; Wilson, Christy; Palmeri, Mark; Smith, Stephen

    2013-01-01

    In this study, we investigated the feasibility of using 3.5-Fr (3 Fr = 1 mm) circular phased-array intravascular ultrasound (IVUS) catheters for minimally invasive, image-guided hyperthermia treatment of tumors in the brain. Feasibility was demonstrated in two ways: (1) by inserting a 3.5-Fr IVUS catheter through skull burr holes, for 20 MHz brain imaging in the pig model, and (2) by testing a modified circular array for therapy potential with 18.5-MHz and 9-MHz continuous wave (CW) excitatio...

  13. Preliminary study of tolerance of ambiguity of individuals reporting paranormal experiences.

    Science.gov (United States)

    Houran, J

    1998-02-01

    This research tested the notion that poltergeist-like experiences reflect the need to explain anomalous personal experiences. Thus, it was hypothesized that percipients of poltergeists would score lower on tolerance of ambiguity than controls. Further, it was hypothesized that tolerance of ambiguity would negatively correlate with the number of different categories of poltergeist experience. 30 self-identified percipients of poltergeist-like phenomena and 30 self-identified nonpercipients of the paranormal were administered the Rydell-Rosen Ambiguity Tolerance Scale and Houran and Lange's Poltergeist Experiences Checklist. Results partially supported predictions. Percipients of the paranormal scored significantly lower on tolerance of ambiguity than nonpercipients, but scores on the experiences checklist did not significantly correlate with scores on tolerance of ambiguity. The results supported the main hypothesis but more detailed research is needed to clarify the roles of age and tolerance of ambiguity in the perception of anomalous phenomena.

  14. Orientale and South Pole-Aitken basins on the Moon: Preliminary Galileo imaging results

    Science.gov (United States)

    Head, J.; Fischer, E.; Murchie, S.; Pieters, C.; Plutchak, J.; Sunshine, J.; Belton, M.; Carr, M.; Chapman, C.; Davies, M.

    During the Earth-Moon flyby the Galileo Solid State Imaging System obtained new information on the landscape and physical geology of the Moon. Multicolor Galileo images of the Moon reveal variations in color properties of the lunar surface. Using returned lunar samples as a key, the color differences can be interpreted in terms of variations in the mineral makeup of the lunar rocks and soil. The combined results of Apollo landings and multicolor images from Galileo allow extrapolation of surface composition to areas distant from the landing sites, including the far side invisible from Earth.

  15. Time Integrated Soft X-ray Imaging in High Intensity Laser Experiments (thesis)

    Energy Technology Data Exchange (ETDEWEB)

    Stafford, David [Univ. of California, Davis, CA (United States)

    2009-01-01

    2009 marks a significant achievement and the dawn of a new era in high intensity laser research with the final commissioning of all 192 beams at the National Ignition Facility (NIF). NIF is a department of energy (DOE) funded project more than 10 years in the making located at the Lawrence Livermore National Laboratory (LLNL). The following research was done as one of many preliminary experiments done to prepare for these historic events. The primary focus of the experimental campaign this paper addresses is to test and develop a thermal x-radiation source using a short pulse laser. This data is hoped to provide information about the thermal transport mechanisms important in the development of prediction models in High Energy Density (HED) science. One of several diagnostics fielded was a soft x-ray imager (SXRI) which is detailed in this paper. The SXRI will be used to measure the relative size of the heated region and also the relative level of specific x-ray emissions among several shot and target configurations. The laser system used was the Titan laser located in the Jupiter Laser Facility (JLF) at Lawrence Livermore National Laboratory (LLNL). Titan uses the JLF Janus Nd:glass laser west frontend system with a Optical Parametric Chirped Pulse Amplification (OPCPA) in place of the nanosecond oscillator. The system is capable of producing laser intensities of over a petawatt with several tens of joules delivered in the beam.

  16. Construction and test of a tungsten/Sci-Fi imaging calorimeter for the CREAM experiment

    Energy Technology Data Exchange (ETDEWEB)

    Marrocchesi, P.S. [Department of Physics, University of Siena/INFN, 56 v.Roma, Banchi di Sotto 55, 53100 Siena (Italy)]. E-mail: marrocchesi@pi.infn.it; Ahn, H.S. [Institute for Physics Science and Technology, University of Maryland, College Park, MD 20742 (United States); Bagliesi, M.G. [Department of Physics, University of Siena/INFN, 56 v.Roma, Banchi di Sotto 55, 53100 Siena (Italy); Basti, A. [Department of Physics, University of Siena/INFN, 56 v.Roma, Banchi di Sotto 55, 53100 Siena (Italy); Bigongiari, G. [Department of Physics, University of Siena/INFN, 56 v.Roma, Banchi di Sotto 55, 53100 Siena (Italy); Castellina, A. [IFSI sez. di Torino, 4 Corso Fiume, 10133 Torino (Italy); Ganel, O. [Institute for Physics Science and Technology, University of Maryland, College Park, MD 20742 (United States); Lee, M.H. [Institute for Physics Science and Technology, University of Maryland, College Park, MD 20742 (United States); Lomtadze, T. [INFN sez. di Pisa, 1291 v.Livornese S.Piero a Grado, 56010 Pisa (Italy); Lutz, L. [Institute for Physics Science and Technology, University of Maryland, College Park, MD 20742 (United States); Maestro, P. [Department of Physics, University of Siena/INFN, 56 v.Roma, Banchi di Sotto 55, 53100 Siena (Italy); Malinine, A. [Institute for Physics Science and Technology, University of Maryland, College Park, MD 20742 (United States); Meucci, M. [Department of Physics, University of Siena/INFN, 56 v.Roma, Banchi di Sotto 55, 53100 Siena (Italy); Millucci, V. [Department of Physics, University of Siena/INFN, 56 v.Roma, Banchi di Sotto 55, 53100 Siena (Italy); Morsani, F. [INFN sez. di Pisa, 1291 v.Livornese S.Piero a Grado, 56010 Pisa (Italy); Seo, E.S. [Institute for Physics Science and Technology, University of Maryland, College Park, MD 20742 (United States); Zinn, S.Y. [Institute for Physics Science and Technology, University of Maryland, College Park, MD 20742 (United States)

    2004-12-11

    Cosmic Ray Energetics And Mass (CREAM) is a balloon-borne experiment designed to perform direct measurements of cosmic ray composition over the elemental range from proton to iron to the supernova energy scale of 1015eV in a series of balloon flights using the new Ultra Long Duration Balloon (ULDB) capability under development by NASA. The first flight of CREAM will take place at the end of 2004 from Antarctica. The instrument includes a sampling tungsten/scintillating fiber calorimeter preceded by a graphite target with scintillating fiber hodoscopes, a pixelated silicon charge detector, a transition radiation detector and a segmented timing-based particle-charge detector. The thin ionization calorimeter has been designed to operate in the range of energies from a few hundred GeV to 1PeV providing imaging capability in the reconstruction of the showers originating from the interaction of primary nuclei in the carbon target. A twin calorimeter for the second CREAM payload has been built and tested at CERN. Its construction technique and preliminary test results are presented.

  17. Understanding God images and God concepts : Towards a pastoral hermeneutics of the God attachment experience

    NARCIS (Netherlands)

    Counted, Agina Victor

    2015-01-01

    The author looks at the God image experience as an attachment relationship experience with God. Hence, arguing that the God image experience is borne originally out of a parent–child attachment contagion, in such a way that God is often represented in either secure or insecure attachment patterns.

  18. Understanding God images and God concepts : Towards a pastoral hermeneutics of the God attachment experience

    NARCIS (Netherlands)

    Counted, Agina Victor

    2015-01-01

    The author looks at the God image experience as an attachment relationship experience with God. Hence, arguing that the God image experience is borne originally out of a parent–child attachment contagion, in such a way that God is often represented in either secure or insecure attachment patterns. T

  19. Preliminary design of a tangentially viewing imaging bolometer for NSTX-U

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, B. J., E-mail: peterson@LHD.nifs.ac.jp; Mukai, K. [National Institute for Fusion Science, Toki 509-5292 (Japan); SOKENDAI (The Graduate University for Advance Studies), Toki 509-5292 (Japan); Sano, R. [National Institutes for Quantum and Radiological Science and Technology, Naka, Ibaraki 311-0193 (Japan); Reinke, M. L.; Canik, J. M.; Lore, J. D.; Gray, T. K. [Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831 (United States); Delgado-Aparicio, L. F.; Jaworski, M. A. [Princeton Plasma Physics Laboratory, Princeton, New Jersey 08543 (United States); Eden, G. G. van [FOM Institute DIFFER, 5612 AJ Eindhoven (Netherlands)

    2016-11-15

    The infrared imaging video bolometer (IRVB) measures plasma radiated power images using a thin metal foil. Two different designs with a tangential view of NSTX-U are made assuming a 640 × 480 (1280 × 1024) pixel, 30 (105) fps, 50 (20) mK, IR camera imaging the 9 cm × 9 cm × 2 μm Pt foil. The foil is divided into 40 × 40 (64 × 64) IRVB channels. This gives a spatial resolution of 3.4 (2.2) cm on the machine mid-plane. The noise equivalent power density of the IRVB is given as 113 (46) μW/cm{sup 2} for a time resolution of 33 (20) ms. Synthetic images derived from Scrape Off Layer Plasma Simulation data using the IRVB geometry show peak signal levels ranging from ∼0.8 to ∼80 (∼0.36 to ∼26) mW/cm{sup 2}.

  20. Photonic Imaging with Optical Coherence Tomography for Quality Monitoring in the Poultry Industry: a Preliminary Study

    Directory of Open Access Journals (Sweden)

    M Sabuncu

    2015-09-01

    Full Text Available ABSTRACTA photonic imaging method that gives the possibility to measure egg quality was applied. Since the method is non-contact and non-destructive we believe that this photonic imaging method may be successfully integrated in the automated inspection systems in the poultry industry. The method involves scanning an invisible infrared light beam over the eggshell, allowing to detect possible cracks and reveal information about the structure of the eggshell. The high resolution, high quality measurements obtained through optical coherence tomography (OCT make it feasible to be utilized as part of an automated inspection system. In this paper we present an OCT scan image of the egg tip and reconstructed volumetric images of the eggshell surface. The method enables the detection of small cracks on eggs and reveals the detailed inner structures of the cracks.

  1. A facial expression image database and norm for Asian population: a preliminary report

    Science.gov (United States)

    Chen, Chien-Chung; Cho, Shu-ling; Horszowska, Katarzyna; Chen, Mei-Yen; Wu, Chia-Ching; Chen, Hsueh-Chih; Yeh, Yi-Yu; Cheng, Chao-Min

    2009-01-01

    We collected 6604 images of 30 models in eight types of facial expression: happiness, anger, sadness, disgust, fear, surprise, contempt and neutral. Among them, 406 most representative images from 12 models were rated by more than 200 human raters for perceived emotion category and intensity. Such large number of emotion categories, models and raters is sufficient for most serious expression recognition research both in psychology and in computer science. All the models and raters are of Asian background. Hence, this database can also be used when the culture background is a concern. In addition, 43 landmarks each of the 291 rated frontal view images were identified and recorded. This information should facilitate feature based research of facial expression. Overall, the diversity in images and richness in information should make our database and norm useful for a wide range of research.

  2. Gender and urban infrastructural poverty experience in Africa: A preliminary survey in Ibadan city, Nigeria

    Directory of Open Access Journals (Sweden)

    Raimi. A. Asiyanbola

    2012-12-01

    Full Text Available The paper examines gender differences in the urban infrastructural poverty experience in an African city – Ibadan, Nigeria. The result of the cross-sectional survey of 232 households sampled in Ibadan city shows that there is intra-urban variation in the women and men urban infrastructure experience in Ibadan. The result of the correlation analysis shows that there is significant relationship between women and men urban infrastructure experience and the household income, educational level, household size and the stage in the life cycle; only with the urban infrastructure experience of the women is a significant relationship found with the occupation and the responsibility in the household. The result of the multiple linear regression analysis shows that the impact/effect of the socio-cultural, demographic and economic characteristics are more on women experience of urban infrastructure than on men’s experience. While the relative contributions of the economic characteristics, family characteristics and socio-cultural characteristics in that order are all significant in explaining the variance in women’s experience of urban infrastructure, only economic characteristics and family characteristics in that order are found to be significant in the case of the men. Also, the most important socio-cultural demographic and economic variables as shown by the beta coefficients for women are household income, household size, and responsibility in the household, while for men are the household income and the household size. Policy implications of the findings are highlighted in the paper.

  3. Preliminary experiment design of graphite dust emission measurement under accident conditions for HTGR

    Energy Technology Data Exchange (ETDEWEB)

    Peng, Wei, E-mail: pengwei@tsinghua.edu.cn [Institute of Nuclear and New Energy Technology of Tsinghua University, Advanced Nuclear Energy Technology Cooperation Innovation Center, The Key Laboratory of Advanced Nuclear Engineering and Safety, Ministry of Education, Beijing 100084 (China); Chen, Tao; Sun, Qi; Wang, Jie [Institute of Nuclear and New Energy Technology of Tsinghua University, Advanced Nuclear Energy Technology Cooperation Innovation Center, The Key Laboratory of Advanced Nuclear Engineering and Safety, Ministry of Education, Beijing 100084 (China); Yu, Suyuan, E-mail: suyuan@tsinghua.edu.cn [Center for Combustion Energy, The Key Laboratory for Thermal Science and Power Engineering, Ministry of Education, Tsinghua University, Beijing 100084 (China)

    2017-05-15

    Highlights: • A theoretical analysis is used to predict the total graphite dust release for an AVR LOCA. • Similarity criteria must be satisfied between the experiment and the actual HTGR system. • Model experiments should be conducted to predict the graphite dust resuspension rate. - Abstract: The graphite dust movement behavior is significant for the safety analyses of high-temperature gas cooled reactor (HTGR). The graphite dust release for accident conditions is an important source term for HTGR safety analyses. Depressurization release tests are not practical in HTGR because of a radioactivity release to the environment. Thus, a theoretical analysis and similarity principles were used to design a group of modeling experiments. Modeling experiments for fan start-up and depressurization process and actual experiments of helium circulator start-up in an HTGR were used to predict the rate of graphite dust resuspension and the graphite dust concentration, which can be used to predict the graphite dust release during accidents. The modeling experiments are easy to realize and the helium circulator start-up test does not harm the reactor system or the environment, so this experiment program is easily achieved. The revised Rock’n’Roll model was then used to calculate the AVR reactor release. The calculation results indicate that the total graphite dust releases during a LOCA will be about 0.65 g in AVR.

  4. Study to perform preliminary experiments to evaluate particle generation and characterization techniques for zero-gravity cloud physics experiments

    Science.gov (United States)

    Katz, U.

    1982-01-01

    Methods of particle generation and characterization with regard to their applicability for experiments requiring cloud condensation nuclei (CCN) of specified properties were investigated. Since aerosol characterization is a prerequisite to assessing performance of particle generation equipment, techniques for characterizing aerosol were evaluated. Aerosol generation is discussed, and atomizer and photolytic generators including preparation of hydrosols (used with atomizers) and the evaluation of a flight version of an atomizer are studied.

  5. Preliminary design of laser-induced breakdown spectroscopy for proto-Material Plasma Exposure eXperiment.

    Science.gov (United States)

    Shaw, G; Martin, M Z; Martin, R; Biewer, T M

    2014-11-01

    Laser-induced breakdown spectroscopy (LIBS) is a technique for measuring surface matter composition. LIBS is performed by focusing laser radiation onto a target surface, ablating the surface, forming a plasma, and analyzing the light produced. LIBS surface analysis is a possible diagnostic for characterizing plasma-facing materials in ITER. Oak Ridge National Laboratory has enabled the initial installation of a laser-induced breakdown spectroscopy diagnostic on the prototype Material-Plasma Exposure eXperiment (Proto-MPEX), which strives to mimic the conditions found at the surface of the ITER divertor. This paper will discuss the LIBS implementation on Proto-MPEX, preliminary design of the fiber optic LIBS collection probe, and the expected results.

  6. The Thirty Gigahertz Instrument Receiver for the QUIJOTE Experiment: Preliminary Polarization Measurements and Systematic-Error Analysis

    Science.gov (United States)

    Casas, Francisco J.; Ortiz, David; Villa, Enrique; Cano, Juan L.; Cagigas, Jaime; Pérez, Ana R.; Aja, Beatriz; Terán, J. Vicente; de la Fuente, Luisa; Artal, Eduardo; Hoyland, Roger; Génova-Santos, Ricardo

    2015-01-01

    This paper presents preliminary polarization measurements and systematic-error characterization of the Thirty Gigahertz Instrument receiver developed for the QUIJOTE experiment. The instrument has been designed to measure the polarization of Cosmic Microwave Background radiation from the sky, obtaining the Q, U, and I Stokes parameters of the incoming signal simultaneously. Two kinds of linearly polarized input signals have been used as excitations in the polarimeter measurement tests in the laboratory; these show consistent results in terms of the Stokes parameters obtained. A measurement-based systematic-error characterization technique has been used in order to determine the possible sources of instrumental errors and to assist in the polarimeter calibration process. PMID:26251906

  7. The Thirty Gigahertz Instrument Receiver for the QUIJOTE Experiment: Preliminary Polarization Measurements and Systematic-Error Analysis

    Directory of Open Access Journals (Sweden)

    Francisco J. Casas

    2015-08-01

    Full Text Available This paper presents preliminary polarization measurements and systematic-error characterization of the Thirty Gigahertz Instrument receiver developed for the QUIJOTE experiment. The instrument has been designed to measure the polarization of Cosmic Microwave Background radiation from the sky, obtaining the Q, U, and I Stokes parameters of the incoming signal simultaneously. Two kinds of linearly polarized input signals have been used as excitations in the polarimeter measurement tests in the laboratory; these show consistent results in terms of the Stokes parameters obtained. A measurement-based systematic-error characterization technique has been used in order to determine the possible sources of instrumental errors and to assist in the polarimeter calibration process.

  8. Potential flow calculations and preliminary wing design in support of an NLF variable sweep transition flight experiment

    Science.gov (United States)

    Waggoner, E. G.; Phillips, P. S.; Viken, J. K.; Davis, W. H.

    1985-01-01

    NASA Langley and NASA Ames-Dryden have defined a variable-sweep transition-flight experiment utilizing the F-14 aircraft to enhance understanding of the interaction of crossflow and Tollmien-Schlichting instabilities on a laminar-boundary-layer transition. The F-14 wing outer panel will be modified to generate favorable pressure gradients on the upper wing surface over a wide range of flight conditions. Extensive computations have been performed using two-dimensional and three-dimensional transonic analysis codes. Flight-test and computational data are compared and shown to validate the applicability of the three-dimensional codes (WBPPW and TAWFIVE). In addition, results from two preliminary glove designs derived from two different approaches to the design problem are presented. Advantages and disadvantages of each approach are identified, and it is concluded that coupling an analysis code with an automated design procedure yields a powerful code with distinct advantages over a 'cut-and-dry' approach.

  9. [Preliminary research on application of Q method in studying experiences of Chinese medicine famous veteran doctors].

    Science.gov (United States)

    Liu, Meng-Yu; Peng, Jin; Jiang, Miao

    2010-10-01

    As the stands, one-sidedness of subjective understanding and subjective bias is surely existed in the study of Chinese medicine (CM) doctors' experiences, so to find appropriate methods for inheriting the real experiences of experts is needed. Since CM thinking presents as a system integral way of intention thinking and a mental process of subject, to study CM experts' experiences in virtue of Q method, a psychological research method for the subjective sense, must be feasible. The application of Q method was inspected in this article, it was considered to be capable of sorting the experts, integrating the opinions of experts and comparing their opinions from multi-pointviews. A test investigation was carried out by applying Q method to analyze the CM measures, getting from some chosen gynecology specialists, for regain pregnancy in women underwent spontaneous abortion, for exploring the applicative value of Q method in the co-cognizance formation of experts' experiences.

  10. Preliminary study of religious, spiritual and mystical experiences. Thematic analysis of Poles adult’s narratives

    Directory of Open Access Journals (Sweden)

    Marta Magdalena Boczkowska

    2016-07-01

    Full Text Available The aim of this study was to examine narratives of the personal religious, spiritual and mystical experiences of adult Poles (N = 74 and their impact on narrative identity. The method for collecting qualitative data about individual understandings and spiritual, religious and mystical experiences was the narrative interview, developed on the basis of the Life Story Interview. During the analysis, the following key topics were identified: awareness of the presence/protection of God, a peak experience, the awareness of oneness with nature and the world, and a sense of closeness/contact with a person who has died. This study provides specific information on the spiritual, religious and mystical experiences of the investigated group of Poles.

  11. Preliminary Results from the GPS-Reflections Mediterranean Balloon Experiment (GPSR MEBEX)

    Science.gov (United States)

    Garrison, James L.; Ruffini, Giulio; Rius, Antonio; Cardellach, Estelle; Masters, Dallas; Armathys, Michael; Zavorotny, Valery

    2000-01-01

    An experiment to collect bistatically scattered GPS signals from a balloon at 37 km altitude has been conducted. This experiment represented the highest altitude to date that such signals were successfully recorded. The flight took place in August 1999 over the Mediterranean sea, between a launch in Sicily and recovery near Nerpio, a town in the Sierra de Segura, Albacete province of Huelva, Spain. Results from this experiment are presented, showing the waveform shape as compared to theoretical calculations. These results will be used to validate analytical models which form the basis of wind vector retrieval algorithms. These algorithms are already being validated from aircraft altitudes, but may be applied to data from future spaceborne GPS receivers. Surface wind data from radiosondes were used for comparison. This experiment was a cooperative project between NASA, the IEEC in Barcelona, and the University of Colorado at Boulder.

  12. Preliminary Results from the GPS-Reflections Mediterranean Balloon Experiment (GPSR-MEBEX)

    Science.gov (United States)

    Garrison, James L.; Ruffini, Giulio; Rius, Antonio; Cardellach, Estelle; Masters, Dallas; Armatys, Michael; Zavorotny, Valery; Bauer, Frank H. (Technical Monitor)

    2000-01-01

    An experiment to collect bistatically scattered GPS signals from a balloon at 37 km altitude has been conducted. This experiment represented the highest altitude to date that such signals were successfully recorded. The flight took place in August 1999 over the Mediterranean sea, between a launch in Sicily and recovery near Nerpio, a town in the Sierra de Segura, Albacete province of Huelva, Spain. Results from this experiment are presented, showing the waveform shape as compared to theoretical calculations. These results will be used to validate analytical models which form the basis of wind vector retrieval algorithms. These algorithms are already being validated from aircraft altitudes, but may be applied to data from future spacebourne GPS receivers. Surface wind data from radiosondes were used for comparison. This experiment was a cooperative project between NASA, the IEEC in Barcelona, and the University of Colorado at Boulder.

  13. Greenhouse Gas Laser Imaging Tomography Experiment (GreenLITE

    Directory of Open Access Journals (Sweden)

    Dobler Jeremy

    2016-01-01

    Full Text Available Exelis has recently developed a novel laser-based instrument to aid in the autonomous real-time monitoring and mapping of CO2 concentration over a two-dimensional area. The Greenhouse gas Laser Imaging Tomography Experiment (GreenLITE instrument uses two transceivers and a series of retroreflectors to continuously measure the differential transmission over a number of overlapping lines of sight or “chords”, forming a plane. By inverting the differential transmission measurements along with locally measured temperature (T, pressure (P and relative humidity (RH the average concentration of CO2 along each chord can be determined and, based on the overlap between chords, a 2D map of CO2 concentration over the measurement plane can be estimated. The GreenLITE system was deployed to the Zero Emissions Research and Technology (ZERT center in Bozeman, Montana, in Aug-Sept 2014, where more than 200 hours of data were collected over a wide range of environmental conditions, while utilizing a controlled release of CO2 into a segmented underground pipe [1]. The system demonstrated the ability to identify persistent CO2 sources at the test facility and showed strong correlation with an independent measurement using a LI-COR based system. Here we describe the measurement approach, instrument design, and results from the deployment to the ZERT site.

  14. Blastocyst transfer for patients with multiple assisted reproduction treatment failures: preliminary experience.

    Science.gov (United States)

    Sakkas, D; Percival, G; D'Arcy, Y; Lenton, W; Sharif, K; Afnan, M

    2001-01-01

    This preliminary study reports the results obtained from a patient group in which blastocyst culture and transfer were performed, and discusses the advantages and disadvantages of introducing blastocyst transfer in a clinic. Twenty-six patients who had failed to achieve a pregnancy in previous in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) treatments were offered the choice of a fresh cycle with culture to the blastocyst stage. Of the 26 patients who elected to attempt blastocyst culture, 11 opted to have transfer on day 2 or day 3 due to low numbers of embryos. Of the 15 patients who proceeded to blastocyst culture, 46.2% of the embryos cultured reached the blastocyst stage or later and eight of the patients achieved a clinical pregnancy. More oocytes were collected in this patient group, hence the chances of obtaining blastocysts were higher. Offering blastocyst culture to patients with a reasonable chance of success who have had previous multiple assisted reproduction failures is an acceptable way of introducing blastocyst culture into practice.

  15. Outcome measures to evaluate new technology for tonsillectomy: preliminary experience with Coblation

    Science.gov (United States)

    Shah, Udayan K.; Puchalski, Robert; Briggs, Marianne; Chiavacci, Rosetta; Galinkin, Jeffrey

    2001-05-01

    Evaluating the benefits of new surgical technologies does not end with the observation of successful instrument-to- tissue interaction. The impact of new technologies in medicine today is also gauged by improvements in patients' daily activities and performance. We present our outcomes assessment tool for judging the value of applying a novel tonsillectomy technique, plasma- mediated ablation using Coblation technology. Plasma- mediated ablation (PMA) achieves soft tissue resection in the oropharynx by energizing protons to break bonds. Less heat is released, allowing for less thermal injury, and possibly less pain, than with tonsillectomy performed using electrocautery alone. Children undergoing tonsillectomy by PMA, were evaluated using our outcomes-based scale, which asked families to report the degree of interruption of normal activities for the patient and their family during the post-tonsillectomy recovery period. A preliminary review of several outcomes assessments exemplify the benefits and limitations of this tool. The tracking of valuable data is weighed against the limitations of a short time course relative to the duration of disability, and a poor response rate. Future work aims to improve this data collection tool to allow application to other new technologies in otolaryngology.

  16. Estimation of desmosponge (Porifera, Demospongiae) larval settlement rates from short-term recruitment rates: Preliminary experiments

    Science.gov (United States)

    Zea, Sven

    1992-09-01

    During a study of the spatial and temporal patterns of desmosponge (Porifera, Demospongiae) recruitment on rocky and coral reef habitats of Santa Marta, Colombian Caribbean Sea, preliminary attempts were made to estimate actual settlement rates from short-term (1 to a few days) recruitment censuses. Short-term recruitment rates on black, acrylic plastic plates attached to open, non-cryptic substratum by anchor screws were low and variable (0 5 recruits/plate in 1 2 days, sets of n=5 10 plates), but reflected the depth and seasonal trends found using mid-term (1 to a few months) censusing intervals. Moreover, mortality of recruits during 1 2 day intervals was low (0 12%). Thus, short-term censusing intervals can be used to estimate actual settlement rates. To be able to make statistical comparisons, however, it is necessary to increase the number of recruits per census by pooling data of n plates per set, and to have more than one set per site or treatment.

  17. Fibrosis and postoperative fistula of the pancreas: correlation with MR imaging findings--preliminary results.

    Science.gov (United States)

    Watanabe, Haruo; Kanematsu, Masayuki; Tanaka, Kaori; Osada, Shinji; Tomita, Hiroyuki; Hara, Akira; Goshima, Satoshi; Kondo, Hiroshi; Kawada, Hiroshi; Noda, Yoshifumi; Tanahashi, Yukichi; Kawai, Nobuyuki; Yoshida, Kazuhiro; Moriyama, Noriyuki

    2014-03-01

    To assess the potential value of magnetic resonance (MR) imaging in evaluating pancreatic fibrosis and predicting the development of postoperative pancreatic fistula. This retrospective study had institutional review board approval, and the requirement for informed consent was waived. MR images obtained in 29 consecutive patients (15 men, 14 women; mean age, 64.9 years; age range, 21-80 years) who underwent pancreatectomy were evaluated. The pancreas-to-muscle signal intensity (SI) ratio on unenhanced T1- and T2-weighted, dynamic contrast material-enhanced, and diffusion-weighted images and the apparent diffusion coefficient (ADC) of the pancreas were measured. MR imaging parameters were correlated with the degrees of pancreatic fibrosis and expression of activated pancreatic stellate cells (PSCs) by using univariate and multivariate regression analyses and receiver operating characteristic curve analysis. The relationships between the development of postoperative pancreatic fistula and the MR imaging measurements were examined by using logistic regression analysis and the Mann-Whitney U test. Multiple regression analysis showed that pancreas-to-muscle SI ratios on T1-weighted images and ADC values were independently associated with pancreatic fibrosis (r(2) = 0.66, P fistula (1.6 ± 0.2) than for those without (1.2 ± 0.2), and the odds ratio for postoperative pancreatic fistula was 21.3 in patients with an SI ratio of 1.41 and higher. The pancreas-to-muscle SI ratio on T1-weighted MR images of the pancreas may be a potential biomarker for assessment of pancreatic fibrosis and prediction of postoperative pancreatic fistula. RSNA, 2013

  18. Preliminary 3d depth migration of a network of 2d seismic lines for fault imaging at a Pyramid Lake, Nevada geothermal prospect

    Energy Technology Data Exchange (ETDEWEB)

    Frary, R.; Louie, J. [UNR; Pullammanappallil, S. [Optim; Eisses, A.

    2016-08-01

    Roxanna Frary, John N. Louie, Sathish Pullammanappallil, Amy Eisses, 2011, Preliminary 3d depth migration of a network of 2d seismic lines for fault imaging at a Pyramid Lake, Nevada geothermal prospect: presented at American Geophysical Union Fall Meeting, San Francisco, Dec. 5-9, abstract T13G-07.

  19. The OMERACT psoriatic arthritis magnetic resonance imaging scoring system (PsAMRIS): definitions of key pathologies, suggested MRI sequences, and preliminary scoring system for PsA Hands

    DEFF Research Database (Denmark)

    Østergaard, Mikkel; McQueen, Fiona; Wiell, Charlotte

    2009-01-01

    This article describes a preliminary OMERACT psoriatic arthritis magnetic resonance image scoring system (PsAMRIS) for evaluation of inflammatory and destructive changes in PsA hands, which was developed by the international OMERACT MRI in inflammatory arthritis group. MRI definitions of important...

  20. Preliminary evaluation of magnetic resonance fresh blood imaging for diagnosis of Budd-Chiari syndrome

    Institute of Scientific and Technical Information of China (English)

    REN Ke; XU Ke; SUN Wen-ge; CHEN Yu-shuai; QI Xi-xun; LI Ran-liang; JIN An-yu

    2007-01-01

    Background Budd-Chiari syndrome (BCS) is a rare disease with portal hypertension caused by the blockage of the hepatic vein and/or the inferior vena cava (IVC). Angiography is the "golden standard" for diagnosis, but it is an invasive examination. To assess the diagnostic value of a fresh blood imaging (FBI) relative to BCS, we used a magnetic resonance angiography (MRA) with an FBI sequence for a preoperative evaluation of the BCS patients in this study. Methods Fifty patients who were suspected of having BCS after they had been checked by a B-ultrasound were studied. 2D and 3D FBI were performed on a 1.5T superconductive MR scanner. Original images were rebuilt using a maximal intensity projection (MIP) method on the console. Two doctors reviewed all images before they learned of the angiography results. We then compared the diagnoses obtained from the FBI and angiography results to evaluate the diagnostic value of the FBI.Results Forty-one patients were diagnosed as BCS and 9 as non-BCS based on an angiography. The FBI correctly diagnosed 38 patients, incorrectly diagnosed 1 patient, and missed diagnosis in 3 patients. Thus, the diagnostic sensitivity of the FBI is 93% (38/41), the specificity is 89% (8/9) and the accuracy is 92% (46/50). The FBI images of the 13 membranous stenoses of the IVC showed a sudden stenosis of the post-liver segment of the IVC. The Images of the 5 patients with a membranous obstruction of the IVC showed IVC thickening and an absence of blood signals in the post-hepatic segment of the IVC. The images of the 4 patients with the segmental thrombosis of the IVC showed abnormal and intermittent signals in the IVC. The images of the 6 patients with a simple hepatic vein obstruction showed obstructive hepatic veins. The images of the 6 patients with the stenosis of both the IVC and the hepatic veins showed the stenosis of the IVC, the thickening of the hepatic veins and the formation of a compensatory circulation within the liver. Lastly

  1. Comparison of MRI and renal cortical scintigraphy findings in childhood acute pyelonephritis: preliminary experience

    Energy Technology Data Exchange (ETDEWEB)

    Kovanlikaya, Arzu; Okkay, Nese; Cakmakci, Handan E-mail: cakmakh@egenet.com.tr; Oezdogan, Oezhan; Degirmenci, Berna; Kavukcu, Salih

    2004-01-01

    Objective: The diagnosis of acute pyelonephritis in children remains a clinical challenge. It may cause permanent renal scar formation and results in the chronic renal failure if prompt diagnosis and treatment are delayed. The purpose of this study is to compare magnetic resonance imaging (MRI) and renal cortical scintigraphy (RCS) findings in childhood acute pyelonephritis and to determine pyelonephritic foci in the acute phase. Materials and method: Twenty children (15 females and five males) with symptoms dysuria, enuresis, costovertebral pain, fever of 37.5 degree sign C or more and/or positive urine culture were imaged by unenhanced turbo spin echo T2, spin echo T1-weighted, pre- and post-gadolinium inversion recovery MRI and RCS. Both imaging techniques were read independently by two radiologists and nuclear medicine specialists. Sensitivity and specificity of MRI in detecting acute pyelonephritic foci and scar lesions were calculated. Furthermore, in order to calculate the reliability of MRI over RCS in differentiating scar tissue and acute pyelonephritic foci, follow-up MRI studies were done in six patients after treatment of acute pyelonephritis. Results: Sensitivity and specificity of MRI in the detection of pyelonephritic lesions were found to be 90.9 and 88.8%, respectively. There is no statistically significant difference in lesion detection between the two diagnostic modalities (P>0.05). Conclusion: Post-gadolinium MR images show significant correlation with RCS in the determination of renal pathology. Moreover, the ability of discriminating acute pyelonephritic foci and renal scar in early stages of disease is the superiority of MRI.

  2. MR imaging of the knee using fat suppression technique: a preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    Suh, Jin Suck; Kim, Mi Hye; Cho, Jae Hyun; Park, Chang Yun; Lee, Yeon Hee [Yonsei University College of Medicine, Seoul (Korea, Republic of); Kim, Yong Soo [Inje University College of Medicine, Kimhae (Korea, Republic of)

    1994-03-15

    The purpose of this study is to evaluate the usefulness of fat suppression technique for MR imaging of the knee. Twenty-eight knees of 26 patients were imaged at a 1.5 T MR system. Sagittal and coronal T2-weighted spin echo imaged (SET2) and sagittal fat suppression SET2(FSSE) were obtained in all cases. We used a chemical shift imaging method for fat suppression. We compared FSSE with SET2 in terms of the conspicuity of lesions of menisci, cruciate ligaments, cartilage, bone and soft tissue of the knee. Meniscal lesions were detected on FSSE and SET2 as well. FSSE depicted the lesion more conspicuously in 6 cases. For the depiction of ACL tear, SET2 was superior to FSSE in 5 cases. FSSE was better for the visualization of the normal structure of cartilage and it also depicted the cartilaginous lesions more conspicuously in 3 cases. Though bone bruise could be detected on both techniques, FSSE was better. FSSE could provide the improved delineation of menisci, cartilage, bone bruise and other soft tissues except the injuries of anterior cruciate ligament. Although FSSE is a reliable method, it can not replace SET2. It may be used as a complemental method in the imaging of the knee.

  3. Imaging Arterial Fibres Using Diffusion Tensor Imaging—Feasibility Study and Preliminary Results

    Directory of Open Access Journals (Sweden)

    Kerskens Christian

    2010-01-01

    Full Text Available Abstract MR diffusion tensor imaging (DTI was used to analyze the fibrous structure of aortic tissue. A fresh porcine aorta was imaged at 7T using a spin echo sequence with the following parameters: matrix 128 128 pixel; slice thickness 0.5 mm; interslice spacing 0.1 mm; number of slices 16; echo time 20.3 s; field of view 28 mm 28 mm. Eigenvectors from the diffusion tensor images were calculated for the central image slice and the averaged tensors and the eigenvector corresponding to the largest eigenvalue showed two distinct angles corresponding to near and to the transverse plane of the aorta. Fibre tractography within the aortic volume imaged confirmed that fibre angles were oriented helically with lead angles of and . The findings correspond to current histological and microscopy data on the fibrous structure of aortic tissue, and therefore the eigenvector maps and fibre tractography appear to reflect the alignment of the fibers in the aorta. In view of current efforts to develop noninvasive diagnostic tools for cardiovascular diseases, DTI may offer a technique to assess the structural properties of arterial tissue and hence any changes or degradation in arterial tissue.

  4. Imaging Arterial Fibres Using Diffusion Tensor Imaging—Feasibility Study and Preliminary Results

    Directory of Open Access Journals (Sweden)

    Ciaran K. Simms

    2010-01-01

    Full Text Available MR diffusion tensor imaging (DTI was used to analyze the fibrous structure of aortic tissue. A fresh porcine aorta was imaged at 7T using a spin echo sequence with the following parameters: matrix 128 × 128 pixel; slice thickness 0.5 mm; interslice spacing 0.1 mm; number of slices 16; echo time 20.3 s; field of view 28 mm × 28 mm. Eigenvectors from the diffusion tensor images were calculated for the central image slice and the averaged tensors and the eigenvector corresponding to the largest eigenvalue showed two distinct angles corresponding to near 0∘ and 180∘ to the transverse plane of the aorta. Fibre tractography within the aortic volume imaged confirmed that fibre angles were oriented helically with lead angles of 15±2.5∘ and 175±2.5∘. The findings correspond to current histological and microscopy data on the fibrous structure of aortic tissue, and therefore the eigenvector maps and fibre tractography appear to reflect the alignment of the fibers in the aorta. In view of current efforts to develop noninvasive diagnostic tools for cardiovascular diseases, DTI may offer a technique to assess the structural properties of arterial tissue and hence any changes or degradation in arterial tissue.

  5. Fractal Analysis of Elastographic Images for Automatic Detection of Diffuse Diseases of Salivary Glands: Preliminary Results

    Directory of Open Access Journals (Sweden)

    Alexandru Florin Badea

    2013-01-01

    Full Text Available The geometry of some medical images of tissues, obtained by elastography and ultrasonography, is characterized in terms of complexity parameters such as the fractal dimension (FD. It is well known that in any image there are very subtle details that are not easily detectable by the human eye. However, in many cases like medical imaging diagnosis, these details are very important since they might contain some hidden information about the possible existence of certain pathological lesions like tissue degeneration, inflammation, or tumors. Therefore, an automatic method of analysis could be an expedient tool for physicians to give a faultless diagnosis. The fractal analysis is of great importance in relation to a quantitative evaluation of “real-time” elastography, a procedure considered to be operator dependent in the current clinical practice. Mathematical analysis reveals significant discrepancies among normal and pathological image patterns. The main objective of our work is to demonstrate the clinical utility of this procedure on an ultrasound image corresponding to a submandibular diffuse pathology.

  6. Projection-reflection ultrasound images using PE-CMOS sensor: a preliminary bone fracture study

    Science.gov (United States)

    Lo, Shih-Chung B.; Liu, Chu-Chuan; Freedman, Matthew T.; Mun, Seong-Ki; Kula, John; Lasser, Marvin E.; Lasser, Bob; Wang, Yue Joseph

    2008-03-01

    In this study, we investigated the characteristics of the ultrasound reflective image obtained by a CMOS sensor array coated with piezoelectric material (PE-CMOS). The laboratory projection-reflection ultrasound prototype consists of five major components: an unfocused ultrasound transducer, an acoustic beam splitter, an acoustic compound lens, a PE-CMOS ultrasound sensing array (Model I400, Imperium Inc. Silver Spring, MD), and a readout circuit system. The prototype can image strong reflective materials such as bone and metal. We found this projection-reflection ultrasound prototype is able to reveal hairline bone fractures with and without intact skin and tissue. When compared, the image generated from a conventional B-scan ultrasound on the same bone fracture is less observable. When it is observable with the B-scan system, the fracture or crack on the surface only show one single spot of echo due to its scan geometry. The corresponding image produced from the projection-reflection ultrasound system shows a bright blooming strip on the image clearly indicating the fracture on the surface of the solid material. Speckles of the bone structure are also observed in the new ultrasound prototype. A theoretical analysis is provided to link the signals as well as speckles detected in both systems.

  7. Microwave bone imaging: a preliminary scanning system for proof-of-concept.

    Science.gov (United States)

    Ruvio, Giuseppe; Cuccaro, Antonio; Solimene, Raffaele; Brancaccio, Adriana; Basile, Bruno; Ammann, Max J

    2016-09-01

    This Letter introduces a feasibility study of a scanning system for applications in biomedical bone imaging operating in the microwave range 0.5-4 GHz. Mechanical uncertainties and data acquisition time are minimised by using a fully automated scanner that controls two antipodal Vivaldi antennas. Accurate antenna positioning and synchronisation with data acquisition enables a rigorous proof-of-concept for the microwave imaging procedure of a multi-layer phantom including skin, fat, muscle and bone tissues. The presence of a suitable coupling medium enables antenna miniaturisation and mitigates the impedance mismatch between antennas and phantom. The three-dimensional image of tibia and fibula is successfully reconstructed by scanning the multi-layer phantom due to the distinctive dielectric contrast between target and surrounding tissues. These results show the viability of a microwave bone imaging technology which is low cost, portable, non-ionising, and does not require specially trained personnel. In fact, as no a-priori characterisation of the antenna is required, the image formation procedure is very conveniently simplified.

  8. Intracranial dual-mode IVUS and hyperthermia using circular arrays: preliminary experiments.

    Science.gov (United States)

    Patel, Vivek; Light, Edward; Herickhoff, Carl; Grant, Gerald; Britz, Gavin; Wilson, Christy; Palmeri, Mark; Smith, Stephen

    2013-01-01

    In this study, we investigated the feasibility of using 3.5-Fr (3 Fr = 1 mm) circular phased-array intravascular ultrasound (IVUS) catheters for minimally invasive, image-guided hyperthermia treatment of tumors in the brain. Feasibility was demonstrated in two ways: (1) by inserting a 3.5-Fr IVUS catheter through skull burr holes, for 20 MHz brain imaging in the pig model, and (2) by testing a modified circular array for therapy potential with 18.5-MHz and 9-MHz continuous wave (CW) excitation. The imaging transducer's performance was superior to our previous 9-MHz mechanical IVUS prototype. The therapy catheter transducer was driven by CW electrical power at 18.5 MHz, achieving temperature changes reaching +8°C at a depth of 2 mm in a human glioblastoma grown on the flank of a mouse with minimal transducer resistive heating of +2°C. Further hyperthermia trials showed that 9-MHz CW excitation produced temperature changes of +4.5°C at a depth of 12 mm-a sufficient temperature rise for our long-term goal of targeted, controlled drug release via thermosensitive liposomes for therapeutic treatment of 1-cm-diameter glioblastomas.

  9. Preliminary results of a new approach for three-dimensional reconstruction of Dynamic AngioThermography (DATG) images based on the inversion of heat equation.

    Science.gov (United States)

    Brancaccio, R; Bettuzzi, M; Morigi, M P; Casali, F; Levi, G; Baldazzi, G; Inferrera, P

    2016-09-01

    Dynamic AngioThermography (DATG) is a contact-plate technique capable of producing a digital representation of breast vascularity. The inception and growth of a tumor are associated with neoangenesis, which may result in a demonstrable alteration in the regional blood flow, while in normal health conditions the vascularity remains unchanged throughout life. DATG, if included in the clinical evaluation for breast cancer, could potentially improve the accuracy of the diagnosis of this disease. Conventional DATG is limited, however, in that it is a projection (i.e. two-dimensional) imaging technique that does not provide any information on the depth and its effect on the pattern of the perfusion revealed by this technique. In fact, the blood pattern is detected by projecting temperature signals on the plate, thus acquiring a digital two-dimensional image. In this article we propose a new approach for extracting information on depth through the inversion of the Fourier heat equation. The idea is to extract the information along the third axis while acquiring and analyzing the temporal sequence during the process of image formation. The method implemented has been tested on a dedicated "electric phantom" and in one in vivo experiment. In spite of the limits of these preliminary tests, the experimental results have shown that this method makes it possible to obtain a 3D representation of the vascularity. Although it appears to be promising, further validation and characterization of our technique are required. Copyright © 2016 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  10. Acquisition procedures, processing methodologies and preliminary results of magnetic and ROV data collected during the TOMO-ETNA experiment

    Directory of Open Access Journals (Sweden)

    Danilo Cavallaro

    2016-09-01

    Full Text Available The TOMO-ETNA experiment was devised for the investigation of the continental and oceanic crust beneath Mt. Etna volcano and northeastern Sicily up to the Aeolian Islands, through an active source study. In this experiment, a large amount of geophysical data was collected both inland and in the Ionian and Tyrrhenian Seas for identifying the major geological and structural features offshore Mt. Etna and NE Sicily. One of the oceanographic cruises organized within the TOMO-ETNA experiment was carried out on the hydrographic vessel “Galatea” by Italian Navy. During the cruise a detailed magnetic survey and a set of ROV (remotely operated vehicle dives were performed offshore Mt. Etna. The magnetic survey allowed the compilation of a preliminary magnetic map revealing a clear direct relationship between volcanic structures and high frequency magnetic anomalies. Significant positive magnetic anomalies were identified offshore the Timpa area and along the easternmost portion of the Riposto Ridge and correlated to a primitive volcanic edifice and to shallow volcanic bodies, respectively. On the whole, the magnetic anomaly map highlights a clear SW-NE decreasing trend, where high amplitude positive magnetic anomaly pattern of the SW sector passes, northeastwardly, to a main negative one. ROV dives permitted to directly explore the shallowest sectors of the Riposto Ridge and to collect several videos and seafloor samples, allowing us to identify some locally developed volcanic manifestations.

  11. Analysis of Images from Experiments Investigating Fragmentation of Materials

    Energy Technology Data Exchange (ETDEWEB)

    Kamath, C; Hurricane, O

    2007-09-10

    Image processing techniques have been used extensively to identify objects of interest in image data and extract representative characteristics for these objects. However, this can be a challenge due to the presence of noise in the images and the variation across images in a dataset. When the number of images to be analyzed is large, the algorithms used must also be relatively insensitive to the choice of parameters and lend themselves to partial or full automation. This not only avoids manual analysis which can be time consuming and error-prone, but also makes the analysis reproducible, thus enabling comparisons between images which have been processed in an identical manner. In this paper, we describe our approach to extracting features for objects of interest in experimental images. Focusing on the specific problem of fragmentation of materials, we show how we can extract statistics for the fragments and the gaps between them.

  12. [Modular project of the Picture Archiving and Communication System (PACS). Preliminary operational experience. I].

    Science.gov (United States)

    Dalla Palma, L; Ukovich, W; Stacul, F; Cuttin Zernich, R; Carbi, N; Giribona, P

    1990-01-01

    Since september 1988 a PAC System (Comm View by AT & T and Philips) has been operating in the Radiology Department of the University Hospital, Trieste. A research project is presently in progress aiming at providing factual evidence for the evaluation of this kind of systems as far as operational, technical, clinical and economic aspects are concerned. The general approach to this research consists in implementing and monitoring a PACS in a stepwise way, starting with a small system connected to some digital modalities only, in order to test the feasibility and effectiveness of the system within a Radiology Department, and to test the possibility of matching the PACS to the Radiological System. The present paper describes in detail the present configuration of this entry-level system and its technical features. The planned development (october 1989) is also depicted. Further developments devise at managing in an integrated way all the radiological images of the four hospitals of Trieste. At present, the PACS is currently used to manage and store on optical disks all the images acquired from the connected modalities plus the related reports, and to perform the reporting sessions for CT examinations (brain and abdomen). The present research effort is devoted to two main areas: clinical evaluation and operational analysis. The object of the operational analysis was the assessment of the impact of PACS on the operations of a Radiology Department. The general approach followed for this research consists in analysing the procedures as they are performed in the conventional way (manual operations), and comparing them to the way they are, or could be, performed using a PACS System (automatic operations). This stage of the project is divided into three phases, concerning respectively the analysis of the organization and operations before PACS, the analysis of the impact of PACS in its initial configuration and the forecast of the influence of PACS in its future setting. A

  13. Relations among media influence, body image, eating concerns, and sexual orientation in men: A preliminary investigation.

    Science.gov (United States)

    Carper, Teresa L Marino; Negy, Charles; Tantleff-Dunn, Stacey

    2010-09-01

    The current study explored the relation between sexual orientation, media persuasion, and eating and body image concerns among 78 college men (39 gay; 39 straight). Participants completed measures of sexual orientation, eating disorder symptoms, appearance-related anxiety, perceived importance of physical attractiveness, perceptions of media influence, and media exposure. Gay men scored significantly higher on drive for thinness, body dissatisfaction, and body image-related anxiety than their straight counterparts. Additionally, perceptions of media influence were higher for gay men, and significantly mediated the relation between sexual orientation and eating and body image concerns. Sexual orientation also moderated the relation between perceived media influence and beliefs regarding the importance of physical attractiveness, as this relation was significant for gay men, but not straight men. The current findings suggest that gay men's increased vulnerability to media influence partially accounts for the relatively high rate of eating pathology observed in this population.

  14. Preliminary studies for the ORganics Exposure in Orbit (OREOcube) Experiment on the International Space Station

    Science.gov (United States)

    Alonzo, Jason; Fresneau, A.; Elsaesser, A.; Chan, J.; Breitenbach, A.; Ehrenfreund, P.; Ricco, A.; Salama, F.; Mattioda, A.; Santos, O.; Cottin, H.; Dartois, E.; d'Hendecourt, L.; Demets, R.; Foing, B.; Martins, Z.; Sephton, M.; Spaans, M.; Quinn, R.

    2013-01-01

    Organic compounds that survive in uncommon space environments are an important astrobiology focus. The ORganics Exposure in Orbit (OREOcube) experiment will investigate, in real time, chemical changes in organic compounds exposed to low Earth orbit radiation conditions on an International Space Station (ISS) external platform. OREOcube is packaged as an identical pair of 10-cm cube instruments, each weighing electronics, microcontroller, and data storage to make each cube an autonomous stand-alone instrument package requiring only a standard power and data interface. We have characterized the influence of mineralogically relevant inorganic materials on the stability, modification, and degradation of the organic molecules under ground laboratory experimental conditions. The results of our laboratory experiments will be used as the basis for the selection of samples for further investigations on the OREOcube ISS experiment. OREOcube is an international collaboration between the European Space Agency, the National Aeronautics and Space Administration, and University partners.

  15. Measuring Three-Dimensional Thorax Motion Via Biplane Radiographic Imaging: Technique and Preliminary Results.

    Science.gov (United States)

    Baumer, Timothy G; Giles, Joshua W; Drake, Anne; Zauel, Roger; Bey, Michael J

    2016-01-01

    Measures of scapulothoracic motion are dependent on accurate imaging of the scapula and thorax. Advanced radiographic techniques can provide accurate measures of scapular motion, but the limited 3D imaging volume of these techniques often precludes measurement of thorax motion. To overcome this, a thorax coordinate system was defined based on the position of rib pairs and then compared to a conventional sternum/spine-based thorax coordinate system. Alignment of the rib-based coordinate system was dependent on the rib pairs used, with the rib3:rib4 pairing aligned to within 4.4 ± 2.1 deg of the conventional thorax coordinate system.

  16. Preliminary Results on VLT K-band Imaging Observations of GRB Host Galaxies

    Indian Academy of Sciences (India)

    E. Le Floc’h; I. F. Mirabel; P.-A. Duc

    2002-03-01

    We have obtained -band imaging observations of Gamma-Ray Burst (GRB) host galaxies with the near-infrared spectro-imager ISAAC installed on the Very Large Telescope at Paranal (Chile). The derived magnitudes, combined with other photometric data taken from the literature, are used to investigate the – colors of GRB hosts. We do not find any extremely reddened starbursts in our sample, despite the capability of GRBs to trace star formation even in dusty regions. The observed – colors are on the contrary typical of irregular and spiral blue galaxies at high redshift.

  17. Fast Blood Vector Velocity Imaging: Simulations and Preliminary In Vivo Results

    DEFF Research Database (Denmark)

    Udesen, Jesper; Gran, Fredrik; Hansen, Kristoffer Lindskov

    2007-01-01

    for each pulse emission. 2) The transmitted pulse consists of a 13 bit Barker code which is transmitted simultaneously from each transducer element. 3) The 2-D vector velocity of the blood is found using 2-D speckle tracking between segments in consecutive speckle images. III Results: The method was tested...... rate can be significantly increased, and the full 2-D vector velocity of the blood can be estimated. II Method: The method presented in this paper uses three techniques: 1) The ultrasound is not focused during the transmit of the ultrasound signals, and a full speckle image of the blood can be acquired...

  18. Preliminary experience using dynamic MRI at 3.0 tesla for evaluation of soft tissue tumors

    Energy Technology Data Exchange (ETDEWEB)

    Park, Micheal; Jee, Won Hee; Jung, Joon Yong [Dept. of Radiology, Seoul St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, Seoul (Korea, Republic of); Kim, Sun Ki [Dept. of Radiology, Incheon St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, Incheon (Korea, Republic of); Lee, So Yeon [Dept. of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2013-01-15

    We aimed to evaluate the use of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) at 3.0 T for differentiating the benign from malignant soft tissue tumors. Also we aimed to assess whether the shorter length of DCE-MRI protocols are adequate, and to evaluate the effect of temporal resolution. Dynamic contrast-enhanced magnetic resonance imaging, at 3.0 T with a 1 second temporal resolution in 13 patients with pathologically confirmed soft tissue tumors, was analyzed. Visual assessment of time-signal curves, subtraction images, maximal relative enhancement at the first (maximal peak enhancement [Emax]/1) and second (Emax/2) minutes, Emax, steepest slope calculated by using various time intervals (5, 30, 60 seconds), and the start of dynamic enhancement were analyzed. The 13 tumors were comprised of seven benign and six malignant soft tissue neoplasms. Washout on time-signal curves was seen on three (50%) malignant tumors and one (14%) benign one. The most discriminating DCE-MRI parameter was the steepest slope calculated, by using at 5-second intervals, followed by Emax/1 and Emax/2. All of the steepest slope values occurred within 2 minutes of the dynamic study. Start of dynamic enhancement did not show a significant difference, but no malignant tumor rendered a value greater than 14 seconds. The steepest slope and early relative enhancement have the potential for differentiating benign from malignant soft tissue tumors. Short-length rather than long-length DCE-MRI protocol may be adequate for our purpose. The steepest slope parameters require a short temporal resolution, while maximal peak enhancement parameter may be more optimal for a longer temporal resolution.

  19. Preliminary experience with dynamic MR projection angiography in the evaluation of cervicocranial steno-occlusive disease

    Energy Technology Data Exchange (ETDEWEB)

    Wetzel, S.G.; Haselhorst, R.; Bilecen, D.; Radue, E.W. [Section of Neuroradiology, Kantonsspital Basel (Switzerland); Lyrer, P.A. [Dept. of Neurology, Kantonsspital Basel (Switzerland); Seifritz, E. [Psychiatric University Hospital Basel (Switzerland); Bongartz, G. [Inst. for Diagnostic Radiology, Kantonsspital Basel (Switzerland); Scheffler, K. [Department of Diagnostic Radiology, University of Freiburg, Freiburg (Germany)

    2001-02-01

    The application of a contrast-enhanced, two-dimensional MR technique, which provides dynamic projection angiograms at a subsecond temporal frame rate for depiction of the cervical and intracranial arteries, was evaluated in three healthy volunteers and seven patients with various cervicocranial steno-occlusive diseases. Intra-arterial digital subtraction angiography (DSA) served as standard of reference for findings in the patients. Magnetic resonance projection angiography (MRPA) was performed on a standard 1.5-T clinical MR imaging system at intravenous injection of a single dose of contrast agent (0.1 mmol/kg GdDTPA-BMA). Sixty consecutive images of the cerebral circulation were acquired at a temporal frame rate of 900 ms per image in the coronal plane. The collateral flow and the perfusion of the compromised vessel territory were readily assessed by MPRA in patients with occlusion of the internal cerebral artery (ICA) or middle cerebral artery (MCA). The leptomeningeal collateralisation of these patients was displayed in a dynamic fashion. Furthermore, quantitative perfusion measurement provided a difference between both MCA territories in the time to peak ({delta}DTTP) of the contrast bolus of 1.12 {+-} 0.28 s in five patients with severe stenosis or occlusion of the ICA (healthy volunteers 0.19 {+-} 0.05 s). However, important pathological findings, such as the evaluation of carotid artery stenoses and the intracranial collateral flow pattern in patients with severe carotid stenoses, were not sufficiently assessable as compared with DSA. We conclude that the possibility of obtaining simultaneously information about morphology and perfusion dynamics of the cervicocranial vessels is unique in MPRA as compared with other MR techniques. However, in the applied form, the technique is not a reliable tool for the complete evaluation of the cervicocranial vessels in patients with steno-occlusive disease. (orig.)

  20. Student Satisfaction or Happiness?: A Preliminary Rethink of What Is Important in the Student Experience

    Science.gov (United States)

    Dean, Aftab; Gibbs, Paul

    2015-01-01

    Purpose: This paper aims to investigate the purpose of the complex open system of higher education and to explore this transformative experience as personal flourishing, where students come to terms with a way of being, matching their potentiality with their agency and leading to profound happiness. There is influential, but not uncontested…

  1. Norwegian fjords as potential sites for CO{sub 2} experiments. A preliminary feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    Golmen, Lars G.; Soerensen, Jan; Haugan, Peter; Bakke, Torgeir; Bjerknes, Vilhelm

    1997-12-31

    Large-scale deposition of CO{sub 2} will probably take place deep in the open oceans. But small-scale experiments on plume dynamics and chemical or biological impacts are more conveniently performed in Norwegian fjords. This report describes a feasibility study treating the physical, biological and legal constraints upon such experiments. Several small and large fjord basins with depths exceeding 500 m exist in western Norway. The report gives guidelines to what further steps should be taken to establish an in-situ CO{sub 2} experiment in a fjord. Twenty-six different basins have been identified in terms of maximum depths, municipal adherence etc. Deep water hydrographic conditions vary relatively little from one fjord to another. Data on the dynamical states and on deep water biology are in general lacking and a baseline study on selected fjords should be performed prior to the final selection. User conflicts and legal aspects must be considered and a complete EIA study will probably be required before any CO{sub 2} experiment can be started in a fjord. 60 refs., 13 figs.

  2. Experience Sampling of Positive Affect in Adolescents with Autism: Feasibility and Preliminary Findings.

    Science.gov (United States)

    Kovac, Megan; Mosner, Maya; Miller, Stephanie; Hanna, Eleanor K; Dichter, Gabriel S

    2016-01-01

    Experience sampling is a powerful method for obtaining ecologically valid data from research participants in real-world contexts. Given the urgent need for innovative and sensitive outcome measures in autism spectrum disorder (ASD) research, the present study sought to examine the feasibility of using experience sampling of positive affect and behavior in adolescents with ASD. Nineteen high functioning adolescents with ASD and 20 sex and age matched controls completed smartphone- and Qualtrics® -based experience sampling of positive affect and behavior six times over four days. Adherence was excellent: adolescents with ASD completed 85% of the assessments, compared to 93% in controls, and response rates were not impacted by age or IQ. Groups did not differ in positive affect overall or as a function of activities, nor did groups differ in the proportion of assessments completed during social or nonsocial activities. However, groups did differ in the proportion of assessments completed during preferred activities. Results suggest that smartphone- and Qualtrics® -based experience sampling with high functioning adolescents with ASD is feasible and captures real-world behaviors that would not be possible using laboratory-based measures.

  3. Preliminary analysis of the MER magnetic properties experiment using a computational fluid dynamics model

    DEFF Research Database (Denmark)

    Kinch, K.M.; Merrison, J.P.; Gunnlaugsson, H.P.;

    2006-01-01

    Motivated by questions raised by the magnetic properties experiments on the NASA Mars Pathfinder and Mars Exploration Rover (MER) missions, we have studied in detail the capture of airborne magnetic dust by permanent magnets using a computational fluid dynamics (CFD) model supported by laboratory...

  4. A Preliminary Theoretical Analysis of a Research Experience for Undergraduates Community Model

    Science.gov (United States)

    Castillo-Garsow, Carlos; Castillo-Chavez, Carlos; Woodley, Sherry

    2013-01-01

    The Mathematical and Theoretical Biology Institute (MTBI) is a successful summer research experience for undergraduates, with a strong record of mentoring Ph.D. graduates, particularly, underrepresented minority students. However, the MTBI program was designed for education in research, not for research in education, and the mechanisms of the…

  5. Preliminary Explorations of Indigenous Perspectives of Educational Management: The Evolving Malaysian Experience.

    Science.gov (United States)

    Bajunid, Ibrahim Ahmad

    1996-01-01

    Articulates the need to understand and seek indigenous perspectives of educational management, using Malaysia's experience as an example. To differentiate culture-free and culture-bound content in educational management, the field's core corpus of theories, concepts, and terminology must be identified; the culture-specific ways of knowing must be…

  6. Student Satisfaction or Happiness?: A Preliminary Rethink of What Is Important in the Student Experience

    Science.gov (United States)

    Dean, Aftab; Gibbs, Paul

    2015-01-01

    Purpose: This paper aims to investigate the purpose of the complex open system of higher education and to explore this transformative experience as personal flourishing, where students come to terms with a way of being, matching their potentiality with their agency and leading to profound happiness. There is influential, but not uncontested…

  7. Preliminary studies for the ORganics Exposure in Orbit (OREOcube) Experiment on the International Space Station

    NARCIS (Netherlands)

    Alonzo, Jason; Fresneau, A.; Elsaesser, A.; Chan, J.; Breitenbach, A.; Ehrenfreund, P.; Ricco, A.; Salama, F.; Mattioda, A.; Santos, O.; Cottin, H.; Dartois, E.; d'Hendecourt, L.; Demets, R.; Foing, B.; Martins, Z.; Sephton, M.; Spaans, M.; Quinn, R.

    2013-01-01

    Organic compounds that survive in uncommon space environments are an important astrobiology focus. The ORganics Exposure in Orbit (OREOcube) experiment will investigate, in real time, chemical changes in organic compounds exposed to low Earth orbit radiation conditions on an International Space Stat

  8. Preliminary studies for the ORganics Exposure in Orbit (OREOcube) Experiment on the International Space Station

    NARCIS (Netherlands)

    Alonzo, Jason; Fresneau, A.; Elsaesser, A.; Chan, J.; Breitenbach, A.; Ehrenfreund, P.; Ricco, A.; Salama, F.; Mattioda, A.; Santos, O.; Cottin, H.; Dartois, E.; d'Hendecourt, L.; Demets, R.; Foing, B.; Martins, Z.; Sephton, M.; Spaans, M.; Quinn, R.

    Organic compounds that survive in uncommon space environments are animportant astrobiology focus. The ORganics Exposure in Orbit (OREOcube)experiment will investigate, in real time, chemical changes in organiccompounds exposed to low Earth orbit radiation conditions on anInternational Space Station

  9. Silent game as Model for Examining Student Online Creativity - Preliminary Results from an Experiment

    DEFF Research Database (Denmark)

    Sørensen, Jannick Kirk

    the creative dialogues developed through a very constrained communicative environment. The participants could only communicate their creative ideas by placing standard LEGO bricks on a plate. No talking or any other communication was allowed. The game used in the experiment is an adoption of the so...

  10. Preliminary studies for the ORganics Exposure in Orbit (OREOcube) Experiment on the International Space Station

    NARCIS (Netherlands)

    Alonzo, Jason; Fresneau, A.; Elsaesser, A.; Chan, J.; Breitenbach, A.; Ehrenfreund, P.; Ricco, A.; Salama, F.; Mattioda, A.; Santos, O.; Cottin, H.; Dartois, E.; d'Hendecourt, L.; Demets, R.; Foing, B.; Martins, Z.; Sephton, M.; Spaans, M.; Quinn, R.

    2013-01-01

    Organic compounds that survive in uncommon space environments are animportant astrobiology focus. The ORganics Exposure in Orbit (OREOcube)experiment will investigate, in real time, chemical changes in organiccompounds exposed to low Earth orbit radiation conditions on anInternational Space Station

  11. Preliminary studies for the ORganics Exposure in Orbit (OREOcube) Experiment on the International Space Station

    NARCIS (Netherlands)

    Alonzo, Jason; Fresneau, A.; Elsaesser, A.; Chan, J.; Breitenbach, A.; Ehrenfreund, P.; Ricco, A.; Salama, F.; Mattioda, A.; Santos, O.; Cottin, H.; Dartois, E.; d'Hendecourt, L.; Demets, R.; Foing, B.; Martins, Z.; Sephton, M.; Spaans, M.; Quinn, R.

    2013-01-01

    Organic compounds that survive in uncommon space environments are an important astrobiology focus. The ORganics Exposure in Orbit (OREOcube) experiment will investigate, in real time, chemical changes in organic compounds exposed to low Earth orbit radiation conditions on an International Space Stat

  12. Preliminary evaluation of cryogenic two-phase flow imaging using electrical capacitance tomography

    Science.gov (United States)

    Xie, Huangjun; Yu, Liu; Zhou, Rui; Qiu, Limin; Zhang, Xiaobin

    2017-09-01

    The potential application of the 2-D eight-electrode electrical capacitance tomography (ECT) to the inversion imaging of the liquid nitrogen-vaporous nitrogen (LN2-VN2) flow in the tube is theoretically evaluated. The phase distribution of the computational domain is obtained using the simultaneous iterative reconstruction technique with variable iterative step size. The detailed mathematical derivations for the calculations are presented. The calculated phase distribution for the two detached LN2 column case shows the comparable results with the water-air case, regardless of the much reduced dielectric permittivity of LN2 compared with water. The inversion images of total eight different LN2-VN2 flow patterns are presented and quantitatively evaluated by calculating the relative void fraction error and the correlation coefficient. The results demonstrate that the developed reconstruction technique for ECT has the capacity to reconstruct the phase distribution of the complex LN2-VN2 flow, while the accuracy of the inversion images is significantly influenced by the size of the discrete phase. The influence of the measurement noise on the image quality is also considered in the calculations.

  13. Preliminary Experimental Verification of Synthetic Aperture Flow Imaging Using a Dual Stage Beamformer Approach

    DEFF Research Database (Denmark)

    Li, Ye; Jensen, Jørgen Arendt

    2011-01-01

    A dual stage beamformer method for synthetic aperture flow imaging has been developed. The motivation is to increase the frame rate and still maintain a beamforming quality sufficient for flow estimation that is possible to implement in a commercial scanner. With the new method high resolution im...

  14. Nonrigid registration algorithm for longitudinal breast MR images and the preliminary analysis of breast tumor response

    Science.gov (United States)

    Li, Xia; Dawant, Benoit M.; Welch, E. Brian; Chakravarthy, A. Bapsi; Freehardt, Darla; Mayer, Ingrid; Kelley, Mark; Meszoely, Ingrid; Gore, John C.; Yankeelov, Thomas E.

    2009-02-01

    Although useful for the detection of breast cancers, conventional imaging methods, including mammography and ultrasonography, do not provide adequate information regarding response to therapy. Dynamic contrast enhanced MRI (DCE-MRI) has emerged as a promising technique to provide relevant information on tumor status. Consequently, accurate longitudinal registration of breast MR images is critical for the comparison of changes induced by treatment at the voxel level. In this study, a nonrigid registration algorithm is proposed to allow for longitudinal registration of breast MR images obtained throughout the course of treatment. We accomplish this by modifying the adaptive bases algorithm (ABA) through adding a tumor volume preserving constraint in the cost function. The registration results demonstrate the proposed algorithm can successfully register the longitudinal breast MR images and permit analysis of the parameter maps. We also propose a novel validation method to evaluate the proposed registration algorithm quantitatively. These validations also demonstrate that the proposed algorithm constrains tumor deformation well and performs better than the unconstrained ABA algorithm.

  15. Diffusion tensor imaging and tractography of the median nerve in carpal tunnel syndrome: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Khalil, C.; Hancart, C.; Thuc, V.Le; Cotten, A. [Service de Radiologie Osteoarticulaire, Hopital Roger Salengro, CHRU de Lille (France); Chantelot, C. [Clinique d' Orthopedie, Hopital Roger Salengro, CHRU de Lille (France); Chechin, D. [Philips Medical Systems, Suresnes (France)

    2008-10-15

    The purpose was to demonstrate the feasibility of in vivo diffusion tensor imaging (DTI) and tractography of the human median nerve with a 1.5-T MR scanner and to assess potential differences in diffusion between healthy volunteers and patients suffering from carpal tunnel syndrome. The median nerve was examined in 13 patients and 13 healthy volunteers with MR DTI and tractography using a 1.5-T MRI scanner with a dedicated wrist coil. T1-weighted images were performed for anatomical correlation. Mean fractional anisotropy (FA) and mean apparent diffusion coefficient (ADC) values were quantified in the median nerve on tractography images. In all subjects, the nerve orientation and course could be detected with tractography. Mean FA values were significantly lower in patients (p=0.03). However, no statistically significant differences were found for mean ADC values. In vivo assessment of the median nerve in the carpal tunnel using DTI with tractography on a 1.5-T MRI scanner is possible. Microstructural parameters can be easily obtained from tractography images. A significant decrease of mean FA values was found in patients suffering from chronic compression of the median nerve. Further investigations are necessary to determine if mean FA values may be correlated with the severity of nerve entrapment. (orig.)

  16. White Matter Integrity in Asperger Syndrome: A Preliminary Diffusion Tensor Magnetic Resonance Imaging Study in Adults

    NARCIS (Netherlands)

    O.J.N. Bloemen; Q. Deeley; F. Sundram; E.M. Daly; G.J. Barker; D.K. Jones; T.A.M.J. van Amelsvoort; N. Schmitz; D. Robertson; K.C. Murphy; D.G.M. Murphy

    2010-01-01

    Background: Autistic Spectrum Disorder (ASD), including Asperger syndrome and autism, is a highly genetic neurodevelopmental disorder. There is a consensus that ASD has a biological basis, and it has been proposed that it is a "connectivity" disorder. Diffusion Tensor Magnetic Resonance Imaging (DT-

  17. Cross-Language Transfer of Indexing Concepts for Storage and Retrieval of Moving Images: Preliminary Results.

    Science.gov (United States)

    Turner, James M.

    1996-01-01

    A French-language version of stock footage videotapes from previous research (using English-language data) was prepared, using the same images. The most popular terms identified in each of the two studies for each of the shots are compared, to determine the rate of correspondence between potential indexing terms in each language. (Author/AEF)

  18. Characteristic Dynamic Enhancement Pattern of Magnetic Resonance Imaging for Malignant Thyroid Tumor: A Preliminary Report

    Energy Technology Data Exchange (ETDEWEB)

    Park, Young Nam; Hwang, Hee Young; Shim, Young Sup; Byun, Sung Su; Choi, Hye Young; Kim, Hyung Sik [Dept. of Radiology, Gil Hospital, Gachon University College of Medicine and Science, Incheon (Korea, Republic of)

    2011-11-15

    The purpose of this study is to determine the characteristic dynamic enhancement pattern of magnetic resonance (MR) imaging for malignant thyroid tumor. Eight patients who were pathology proven to have a malignant thyroid tumor, preoperatively. There are 5 papillary carcinomas, 1 medullary carcinoma, 1 follicular carcinoma, and 1 fine needle aspiration biopsy proven atypical cell. Based on preoperative MR imaging, we compared the dynamic MR enhancement pattern relating to the pathologic type. On contrast agent-enhanced dynamic T1-weighted image (T1WI), 5 papillary carcinoma and one medullary carcinoma showed delayed enhancement compared to normal parenchyma. In addition, one follicular carcinoma shows stronger enhancement than normal parenchyma, with one papillary carcinoma showing a persistent decrease in enhancement compared to normal parenchyma. Although this study is limited by a small patients population, the data suggests that delayed enhancement on enhanced dynamic T1WI is a possible characteristic MR finding of a malignant thyroid tumor. I think that the comparison of MR imaging between benign and malignant nodules is required for a correct characterization.

  19. MR imaging of pelvic lymph nodes in primary pelvic carcinoma with ultrasmall superparamagnetic iron oxide (Combidex): preliminary observations.

    Science.gov (United States)

    Harisinghani, M G; Saini, S; Slater, G J; Schnall, M D; Rifkin, M D

    1997-01-01

    The potential of ultrasmall superparamagnetic iron oxide (Combidex)-enhanced MRI of pelvic lymph nodes in patients with primary pelvic carcinoma is evaluated. Fifteen histologically classified lymph nodes in six patients with known primary pelvic cancer (four prostate; one rectum; one uterus) were evaluated with T2-weighted fast spin-echo (FSE) and T2*-weighted gradient-echo (GRE) MRI at 1.5T 12 to 48 hours after intravenous administration of Combidex at a dose of 1.7 mg Fe/kg. Quantitative image evaluation was performed by comparing signal intensity of individual nodes on pre- and postcontrast images. All patients proceeded to pelvic lymph-node biopsy or surgical dissection, where six were found to be benign and nine were malignant. Of the 15 lymph nodes, four nodes showed a decrease in signal intensity. Of these, three, in which signal loss was homogenous were benign, and one, in which the signal-intensity decrease was heterogeneous, was malignant (micrometastases). No signal change was noted in 11 of 15 lymph nodes of which three were benign (inflammatory) and eight were malignant. Combidex is a promising MR contrast agent for evaluating pelvic lymph nodes. Our preliminary observations suggest that the agent is most useful for classifying normal lymph nodes.

  20. Imaging Spectropolarimeter for the Multi-Application Solar Telescope at Udaipur Solar Observatory: Characterization of Polarimeter and Preliminary Observations

    Science.gov (United States)

    Tiwary, Alok Ranjan; Mathew, Shibu K.; Bayanna, A. Raja; Venkatakrishnan, P.; Yadav, Rahul

    2017-04-01

    The Multi-Application Solar Telescope (MAST) is a 50 cm off-axis Gregorian telescope that has recently become operational at the Udaipur Solar Observatory (USO). An imaging spectropolarimeter is being developed as one of the back-end instruments of MAST to gain a better understanding of the evolution and dynamics of solar magnetic and velocity fields. This system consists of a narrow-band filter and a polarimeter. The polarimeter includes a linear polarizer and two sets of liquid crystal variable retarders (LCVRs). The instrument is intended for simultaneous observations in the spectral lines 6173 Å and 8542 Å, which are formed in the photosphere and chromosphere, respectively. In this article, we present results from the characterization of the LCVRs for the spectral lines of interest and the response matrix of the polarimeter. We also present preliminary observations of an active region obtained using the spectropolarimeter. For verification purposes, we compare the Stokes observations of the active region obtained from the Helioseismic Magnetic Imager (HMI) onboard the Solar Dynamics Observatory (SDO) with that of MAST observations in the spectral line 6173 Å. We find good agreement between the two observations, considering the fact that MAST observations are limited by seeing.

  1. Use of thermographic imaging in clinical diagnosis of small animal: preliminary notes

    Directory of Open Access Journals (Sweden)

    Veronica Redaelli

    2014-06-01

    Full Text Available INTRODUCTION. The authors, after a description of the physics of infrared thermographic technique (IRT, analyze the reading of images and the main applications in the veterinary field, compared to the existing literature on the subject and to their experimental researches. IRT lends itself to countless applications in biology, thanks to its characteristics of versatility, lack of invasiveness and high sensitivity. Probably the major limitation to its application in the animal lies in the ease of use and in its extreme sensitivity. MATERIALS AND METHODS. From September 2009 to October 2010, the experimental investigation with the thermo camera took into consideration 110 animals (92 dogs and 18 cats, without any selection criteria. All patients were brought to the Faculty of Veterinary Medicine in Milan University by the owner, to be examined by a specialist, or to undergo one of the following diagnostic procedures: X-rays, computed tomography, or ultrasound examinations; finally some patients were brought in for surgical procedures. With the consent of the owner, 1 to 10 thermographic images were recorded from each clinical case. Results. In this first experimental investigation, thermography has shown a high sensitivity (100%, but a low specificity (44%. This figure excludes the use of thermal imaging technology to replace other imaging techniques such as radiography, computed tomography and magnetic resonance imaging. Furthermore, it does not show any ability to recognize the etiology of the disease, but only the thermal alteration, and this is restricting its use. However, this experimental study has demonstrated that thermography can be used in veterinary medicine, and specifically in dogs and cats. It is hoped that in the field of targeted diseases this technique will become an important tool for diagnostic purposes by using working protocols validated and repeatable.

  2. Biokinetics and imaging with the somatostatin receptor PET radioligand {sup 68}Ga-DOTATOC: preliminary data

    Energy Technology Data Exchange (ETDEWEB)

    Hofmann, M.; Boerner, A.R.; Weckesser, E.; Oei, M.L.; Meyer, G.J.; Knapp, W.H. [Dept. of Nuclear Medicine, Hannover University Medical School (Germany); Maecke, H.; Heppeler, A. [Dept. of Radiology, Kantonspittal, Basel (Switzerland); Schoeffski, P. [Dept. of Haematology and Oncology, Hannover University Medical School (Germany); Schumacher, J.; Henze, M. [German Cancer Research Centre, Heidelberg (Germany)

    2001-12-01

    Somatostatin (SMS) scintigraphy is widely used for the detection and staging of neuroendocrine tumours. Because of its superior imaging properties, there is growing interest in the use of positron emission tomography (PET) technology for SMS scintigraphy. This study addressed the production of gallium-68 DOTATOC, its biokinetics and its clinical performance in detecting SMS-positive tumours and metastases. A preparation protocol was developed, yielding 40% overall incorporation of {sup 68}Ga into the peptide (DOTATOC). After column filtration, the radiochemical purity exceeded 98%. Eight patients with histologically verified carcinoid tumours were injected with 80-250 MBq of this tracer. PET acquisition was initiated immediately after administration and carried out until 3 h post injection. Images were quantitated using standardised uptake values and target to non-target ratios. Prior to {sup 68}Ga-DOTATOC PET, all patients underwent indium-111 octreotide planar and single-photon emission tomographic (SPET) imaging. Arterial activity elimination was bi-exponential, with half-lives of 2.0 ({+-}0.3) min and 48 ({+-}7) min. No radioactive metabolites were detected within 4 h in serum. Maximal tumour activity accumulation was reached 70{+-}20 min post injection. Kidney uptake averaged <50% compared with spleen uptake. Of 40 lesions predefined by computed tomography and/or magnetic resonance imaging, {sup 68}Ga-DOTATOC PET identified 100%, whereas {sup 111}In-octreotide planar and SPET imaging identified only 85%. Tumour to non-tumour ratios ranged from >3:1 for liver ({sup 111}In-octreotide: 1.5:1) to 100:1 for CNS ({sup 111}In-octreotide: 10:1). With {sup 68}Ga-DOTATOC >30% additional lesions were detected. It is concluded that PET using {sup 68}Ga-DOTATOC results in high tumour to non-tumour contrast and low kidney accumulation and yields higher detection rates as compared with {sup 111}In-octreotide scintigraphy. (orig.)

  3. The chest X-ray image features of patients with severe SARS: a preliminary study

    Institute of Scientific and Technical Information of China (English)

    刘晋新; 唐小平; 江松峰; 陈碧华; 张烈光; 黄德扬; 黄务枝; 史红玲; 尹炽标; 陈金城

    2003-01-01

    Objective To study the chest X-ray image features of patients with severe SARS.Methods Chest X-ray image features in 36 patients with severe SARS were retrospectively analyzed. The image characteristics were compared with those of 224 patients with common SARS. Results The important chest X-ray imaging features of 36 patients with severe SARS included small patch of infiltration (n=27, 75.0%), large patch of infiltration (n=22, 61.1%), large area of lung consolidation (n=10, 27.3%), interstitial lung lesion (n=26, 72.2%), ground-glass shadow (n=28, 77.8%), irregular linear opacity (n=15, 41.7%), diffuse lung lesion (n=12, 33.3%), with single lung involved (n=9, 25.0%), and both lungs involved (n=32, 88.9%). The rates of large patch of infiltration, large area of lung consolidation, ground-glass shadow, diffuse lung lesion and involvement of both lungs in patients with severe SARS were significantly higher than those in patients with common type of SARS (all P<0.01). Out of the 11 severe SARS patients who died, nine had large area of ground-glass shadow with air bronchogram in both lungs before death.Conclusions Large patch of infiltration, large area of consolidation, ground-glass shadow, diffuse lung lesion and involvement of both lungs were the main X-ray image characteristics of patients with severe SARS. Large area of ground-glass shadow with air bronchogram in both lungs indicated a bad prognosis.

  4. Greenhouse gas Laser Imaging Tomography Experiment (GreenLITE)

    Energy Technology Data Exchange (ETDEWEB)

    Dobler, Jeremy [Exelis Inc., Fort Wayne, IN (United States); Zaccheo, T. Scott [Exelis Inc., Fort Wayne, IN (United States); Blume, Nathan [Exelis Inc., Fort Wayne, IN (United States); Pernini, Timothy [Exelis Inc., Fort Wayne, IN (United States); Braun, Michael [Exelis Inc., Fort Wayne, IN (United States); Botos, Christopher [Exelis Inc., Fort Wayne, IN (United States)

    2016-03-31

    This report describes the development and testing of a novel system, the Greenhouse gas Laser Imaging Tomography Experiment (GreenLITE), for Monitoring, Reporting and Verification (MRV) of CO2 at Geological Carbon Storage (GCS) sites. The system consists of a pair of laser based transceivers, a number of retroreflectors, and a set of cloud based data processing, storage and dissemination tools, which enable 2-D mapping of the CO2 in near real time. A system was built, tested locally in New Haven, Indiana, and then deployed to the Zero Emissions Research and Technology (ZERT) facility in Bozeman, MT. Testing at ZERT demonstrated the ability of the GreenLITE system to identify and map small underground leaks, in the presence of other biological sources and with widely varying background concentrations. The system was then ruggedized and tested at the Harris test site in New Haven, IN, during winter time while exposed to temperatures as low as -15 °CºC. Additional testing was conducted using simulated concentration enhancements to validate the 2-D retrieval accuracy. This test resulted in a high confidence in the reconstruction ability to identify sources to tens of meters resolution in this configuration. Finally, the system was deployed for a period of approximately 6 months to an active industrial site, Illinois Basin – Decatur Project (IBDP), where >1M metric tons of CO2 had been injected into an underground sandstone basin. The main objective of this final deployment was to demonstrate autonomous operation over a wide range of environmental conditions with very little human interaction, and to demonstrate the feasibility of the system for long term deployment in a GCS environment.

  5. Photoacoustic Imaging in Oncology: Translational Preclinical and Early Clinical Experience.

    Science.gov (United States)

    Valluru, Keerthi S; Wilson, Katheryne E; Willmann, Jürgen K

    2016-08-01

    Photoacoustic imaging has evolved into a clinically translatable platform with the potential to complement existing imaging techniques for the management of cancer, including detection, characterization, prognosis, and treatment monitoring. In photoacoustic imaging, tissue is optically excited to produce ultrasonographic images that represent a spatial map of optical absorption of endogenous constituents such as hemoglobin, fat, melanin, and water or exogenous contrast agents such as dyes and nanoparticles. It can therefore provide functional and molecular information that allows noninvasive soft-tissue characterization. Photoacoustic imaging has matured over the years and is currently being translated into the clinic with various clinical studies underway. In this review, the current state of photoacoustic imaging is presented, including techniques and instrumentation, followed by a discussion of potential clinical applications of this technique for the detection and management of cancer. (©) RSNA, 2016.

  6. Intravascular optical coherence tomography to characterize tissue deformation during angioplasty: preliminary experiments with artery phantoms

    Science.gov (United States)

    Azarnoush, Hamed; Vergnole, Sébastien; Pazos, Valérie; Bisaillon, Charles-Étienne; Boulet, Benoit; Lamouche, Guy

    2012-09-01

    We explored the potential of intravascular optical coherence tomography (IVOCT) to assess deformation during angioplasty balloon inflation. Using a semi-compliant balloon and artery phantoms, we considered two experimental scenarios. The goal for the first scenario was to investigate if variation in the elasticity of the structure surrounding the balloon could be sensed by IVOCT monitoring. In this scenario, we used three single-layer phantoms with various mechanical properties. Image analysis was performed to extract the inner and outer diameters of the phantoms at various pressures. The goal for the second scenario was twofold. First, we investigated the IVOCT capability to monitor a more complex balloon inflation process. The balloon was in a folded state prior to inflation. This allowed studying two stages of deformation: during balloon unfolding and during balloon expansion. Second, we investigated IVOCT capability to monitor the deformation in a three-layer phantom used to better mimic a true artery. So, not only were the IVOCT images processed to provide the inner and outer diameters of the phantom, but the layer thicknesses were also determined. In both scenarios, IVOCT monitoring revealed to be very efficient in providing relevant information about the phantom deformation during balloon inflation.

  7. Characterize Behaviour of Emerging Pollutants in Artificial Recharge: Column Experiments - Experiment Design and Results of Preliminary Tests

    Science.gov (United States)

    Wang, H.; Carrera, J.; Ayora, C.; Licha, T.

    2012-04-01

    Emerging pollutants (EPs) have been detected in water resources as a result of human activities in recent years. They include pharmaceuticals, personal care products, dioxins, flame retardants, etc. They are a source of concern because many of them are resistant to conventional water treatment, and they are harmful to human health, even in low concentrations. Generally, this study aims to characterize the behaviour of emerging pollutants in reclaimed water in column experiments which simulates artificial recharge. One column set includes three parts: influent, reactive layer column (RLC) and aquifer column (AC). The main influent is decided to be Secondary Effluent (SE) of El Prat Wastewater Treatment Plant, Barcelona. The flow rate of the column experiment is 0.9-1.5 mL/min. the residence time of RLC is designed to be about 1 day and 30-40 days for AC. Both columns are made of stainless steel. Reactive layer column (DI 10cm * L55cm) is named after the filling material which is a mixture of organic substrate, clay and goethite. One purpose of the application of the mixture is to increase dissolve organic carbon (DOC). Leaching test in batchs and columns has been done to select proper organic substrate. As a result, compost was selected due to its long lasting of releasing organic matter (OM). The other purpose of the application of the mixture is to enhance adsorption of EPs. Partition coefficients (Kow) of EPs indicate the ability of adsorption to OM. EPs with logKow>2 could be adsorbed to OM, like Ibuprofen, Bezafibrate and Diclofenac. Moreover, some of EPs are charged in the solution with pH=7, according to its acid dissociation constant (Ka). Positively charged EPs, for example Atenolol, could adsorb to clay. In the opposite, negatively charged EPs, for example Gemfibrozil, could adsorb to goethite. Aquifer column (DI 35cm * L1.5m) is to simulate the processes taking place in aquifer in artificial recharge. The filling of AC has two parts: silica sand and

  8. Preliminary study of metabolic radiotherapy with {sup 188}Re via small animal imaging

    Energy Technology Data Exchange (ETDEWEB)

    Antoccia, A. [Dept. of Biology, Univ. Roma3, V.le G. Marconi, I-00146 Rome (Italy); INFN, Sezione Roma3, Via della Vasca Navale 84, I-00146 Rome (Italy); Baldazzi, G. [Dept. of Physics, Univ. Bologna, V.le C. Berti-Pichat 6/2, I-40127 Bologna (Italy); INFN, Sezione Bologna, V.le C. Berti-Pichat 6/2, I-40127 Bologna (Italy); Bello, M. [Dept. of Physics, Univ. Padova, Via F. Marzolo 8, I-35131 Padova (Italy); INFN - LNL, V.le dell' Universita 2, I-35020 Legnaro(Italy)

    2006-01-15

    {sup 188}Re is a {beta}{sup -} (Emax=2.12 MeV) and {gamma} (155 keV) emitter. Since its chemistry is similar to that of the largely employed tracer, {sup 99m}Tc, molecules of hyaluronic acid (HA) have been labelled with {sup 188}Re to produce a target specific radiopharmaceutical. The radiolabeled compound, i.v. injected in healthy mice, is able to accumulate into the liver after a few minutes. To study the effect of metabolic radiotherapy in mice, we have built a small gamma camera based on a matrix of YAP:Ce crystals, with 0.6x0.6x10 mm{sup 3} pixels, read out by a R2486 Hamamatsu PSPMT. A high-sensitivity 20 mm thick lead parallel-hole collimator, with hole diameter 1.5 mm and septa of 0.18 mm, is placed in front of the YAP matrix. Preliminary results obtained with various phantoms containing a solution of {sup 188}Re and with C57 black mice injected with the {sup 188}Re-HA solution are presented. To increase the space resolution and to obtain two orthogonal projections simultaneously we are building in parallel two new cameras to be positioned at 90 degrees. They use a CsI(Tl) matrix with 1x1x5 mm{sup 3} pixels read out by H8500 Hamamatsu Flat panel PMT.

  9. Preliminary study of metabolic radiotherapy with 188Re via small animal imaging

    CERN Document Server

    Baldazzi, G; Muciaccio, A; Navarria, Francesco Luigi; Pancaldi, G; Perrotta, A; Zuffa, M; Boccaccio, P; Uzunov, N; Bello, M; Bernardini, D; Mazzi, U; Moschini, G; Riondato, M; Rosato, A; Garibaldi, F; Pani, R; Antoccia, A; De Notaristefani, F; Hull, G; Cencelli, V O; Sgura, A; Tanzarella, C

    2006-01-01

    188Re is a beta- (Emax = 2.12 MeV) and gamma (155 keV) emitter. Since its chemistry is similar to that of the largely employed tracer, 99mTc, molecules of hyaluronic acid (HA) have been labelled with 188Re to produce a target specific radiopharmaceutical. The radiolabeled compound, i.v. injected in healthy mice, is able to accumulate into the liver after a few minutes. To study the effect of metabolic radiotherapy in mice, we have built a small gamma camera based on a matrix of YAP:Ce crystals, with 0.6x0.6x10 mm**3 pixels, read out by a R2486 Hamamatsu PSPMT. A high-sensitivity 20 mm thick lead parallel-hole collimator, with hole diameter 1.5 mm and septa of 0.18 mm, is placed in front of the YAP matrix. Preliminary results obtained with various phantoms containing a solution of 188Re and with C57 black mice injected with the 188Re-HA solution are presented. To increase the space resolution and to obtain two orthogonal projections simultaneously we are building in parallel two new cameras to be positioned at...

  10. A preliminary assessment of using a white light confocal imaging profiler for cut mark analysis.

    Science.gov (United States)

    Schmidt, Christopher W; Moore, Christopher R; Leifheit, Randell

    2012-01-01

    White light confocal microscopy creates detailed 3D representations of microsurfaces that can be qualitatively and quantitatively analyzed. The study describes its application to the analysis of cut marks on bone, particularly when discerning cuts made by steel tools from those made by stone. The process described comes from a study where cuts were manually made on a cow rib with seven cutting tools, four stone (an unmodified chert flake, a chert biface, a bifacially ground slate fragment, and an unsharpened piece of slate), and three steel (a Swiss Army Knife, a serrate steak knife, and a serrate saw). Kerfs were magnified ×20 and 3D data clouds were generated using a Sensofar(®) White Light Confocal Profiler (WLCP). Kerf profiles and surface areas, volumes, mean depths, and maximum depths were calculated with proprietary software (SensoScan(®) and SolarMap(®)). For the most part, the stone tools make shallower and wider cuts. Kerf floors can be studied at higher magnifications; they were viewed at ×100. When comparing the kerf floors of the unsharpened slate and the serrate steak knife it was found that the slate floor was more uneven, but the serrate steak knife generated more overall relief. Although preliminary, the approach described here successfully distinguishes stone and steel tools; the authors conclude that the WLCP is a promising technology for cut mark analysis because of the very detailed 3D representations it creates and the numerous avenues of analysis it provides.

  11. Preliminary Findings of the Photovoltaic Cell Calibration Experiment on Pathfinder Flight 95-3

    Science.gov (United States)

    Vargas-Aburto, Carlos

    1997-01-01

    The objective of the photovoltaic (PV) cell calibration experiment for Pathfinder was to develop an experiment compatible with an ultralight UAV to predict the performance of PV cells at AM0, the solar spectrum in space, using the Langley plot technique. The Langley plot is a valuable technique for this purpose and requires accurate measurements of air mass (pressure), cell temperature, solar irradiance, and current-voltage(IV) characteristics with the cells directed normal to the direct ray of the sun. Pathfinder's mission objective (95-3) of 65,000 ft. maximum altitude, is ideal for performing the Langley plot measurements. Miniaturization of electronic data acquisition equipment enabled the design and construction of an accurate and light weight measurement system that meets Pathfinder's low payload weight requirements.

  12. Zero-gravity cloud physics laboratory: Candidate experiments definition and preliminary concept studies

    Science.gov (United States)

    Eaton, L. R.; Greco, R. V.; Hollinden, A. B.

    1973-01-01

    The candidate definition studies on the zero-g cloud physics laboratory are covered. This laboratory will be an independent self-contained shuttle sortie payload. Several critical technology areas have been identified and studied to assure proper consideration in terms of engineering requirements for the final design. Areas include chambers, gas and particle generators, environmental controls, motion controls, change controls, observational techniques, and composition controls. This unique laboratory will allow studies to be performed without mechanical, aerodynamics, electrical, or other type techniques to support the object under study. This report also covers the candidate experiment definitions, chambers and experiment classes, laboratory concepts and plans, special supporting studies, early flight opportunities and payload planning data for overall shuttle payload requirements assessments.

  13. Preliminary study of feasibility of an experiment looking for excited state double beta transitions in Tin

    CERN Document Server

    Das, Soumik; Raina, P K; Singh, A K; Rath, P K; Cappella, F; Cerulli, R; Laubenstein, M; Belli, P; Bernabei, R

    2015-01-01

    A first attempt to study the feasibility of an experiment to search for double beta decay in $^{124}$Sn and $^{112}$Sn was carried out by using ultra-low background HPGe detector (244 cm$^{3}$) inside the Gran Sasso National Laboratory (LNGS) of the INFN (Italy). A small sample of natural Sn was examined for 2367.5 h. The radioactive contamination of the sample has been estimated. The data has also been considered to calculate the present sensitivity for the proposed search; half-life limits $\\sim$ $10^{17} - 10^{18}$ years for $\\beta^{+}$EC and EC-EC processes in $^{112}$Sn and $\\sim$ $10^{18}$ years for $\\beta^{-}\\beta^{-}$ transition in $^{124}$Sn were measured. In the last section of the paper the enhancement of the sensitivity for a proposed experiment with larger mass to reach theoretically estimated values of half-lives is discussed.

  14. Video-assisted anal fistula treatment: technical considerations and preliminary results of the first brazilian experience

    OpenAIRE

    Mendes,Carlos Ramon Silveira; FERREIRA, Luciano Santana de Miranda; Sapucaia,Ricardo Aguiar; LIMA, Meyline Andrade; Araujo, Sergio Eduardo Alonso

    2014-01-01

    Backgroung : Anorectal fistula represents an epithelized communication path of infectious origin between the rectum or anal canal and the perianal region. The association of endoscopic surgery with the minimally invasive approach led to the development of the video-assisted anal fistula treatment. Aim : To describe the technique and initial experience with the technique video-assisted for anal fistula treatment. Technique : A Karl Storz video equipment was used. Main steps included the ...

  15. Post-irradiation Examination of the AGR-1 Experiment: Plans and Preliminary Results

    Energy Technology Data Exchange (ETDEWEB)

    Paul Demkowicz

    2001-10-01

    Abstract – The AGR-1 irradiation experiment contains seventy-two individual cylindrical fuel compacts (25 mm long x 12.5 mm diameter) each containing approximately 4100 TRISO-coated uranium oxycarbide fuel particles. The experiment accumulated 620 effective full power days in the Advanced Test Reactor at the Idaho National Laboratory with peak burnups exceeding 19% FIMA. An extensive post-irradiation examination campaign will be performed on the AGR-1 fuel in order to characterize the irradiated fuel properties, assess the in-pile fuel performance in terms of coating integrity and fission metals release, and determine the fission product retention behavior during high temperature accident testing. PIE experiments will include dimensional measurements of fuel and irradiated graphite, burnup measurements, assessment of fission metals release during irradiation, evaluation of coating integrity using the leach-burn-leach technique, microscopic examination of kernel and coating microstructures, and accident testing of the fuel in helium at temperatures up to 1800°C. Activities completed to date include opening of the irradiated capsules, measurement of fuel dimensions, and gamma spectrometry of selected fuel compacts.

  16. Student reflections following exposure to a case-based interprofessional learning experience: Preliminary findings.

    Science.gov (United States)

    Goldberg, Lynette R; Brown, Gina R; Mosack, Victoria A; Fletcher, Phyllis A

    2015-01-01

    This study analyzed students' written reflections following their initial exposure to interprofessional teamwork in case-based problem-solving. A three-hour seminar featuring three sequenced scenarios was developed and offered 12-times over two semesters. A total of 305 students from a variety of healthcare programs worked together with standardized patients in an on-campus laboratory simulating hospital ward and rehabilitation settings. A thematic analysis of students' reflections showed that they valued the shared learning and realistic case study. However, they felt the experience would be strengthened by working in smaller, more representative teams that included students from medicine, psychology, and social work to enable more effective communication and comprehensive case discussion. While useful for future planning, the identified themes did not enable a comparative statistical analysis of what students found helpful and difficult and a re-coding of students' responses now is underway. Implications for measuring the effectiveness of future interprofessional case-based learning center on addressing the identified weaknesses, and establishing a research design that enables a comparison of pre- and post-seminar data, and the effectiveness of the IPE experience compared to profession-specific experiences.

  17. Preliminary analysis of the forest health state based on multispectral images acquired by Unmanned Aerial Vehicle

    Directory of Open Access Journals (Sweden)

    Czapski Paweł

    2015-09-01

    Full Text Available The main purpose of this publication is to present the current progress of the work associated with the use of a lightweight unmanned platforms for various environmental studies. Current development in information technology, electronics and sensors miniaturisation allows mounting multispectral cameras and scanners on unmanned aerial vehicle (UAV that could only be used on board aircraft and satellites. Remote Sensing Division in the Institute of Aviation carries out innovative researches using multisensory platform and lightweight unmanned vehicle to evaluate the health state of forests in Wielkopolska province. In this paper, applicability of multispectral images analysis acquired several times during the growing season from low altitude (up to 800m is presented. We present remote sensing indicators computed by our software and common methods for assessing state of trees health. The correctness of applied methods is verified using analysis of satellite scenes acquired by Landsat 8 OLI instrument (Operational Land Imager.

  18. Fluorescence endoscopic imaging for evaluation of gastric mucosal blood flow: a preliminary study

    Science.gov (United States)

    Bocquillon, Nicolas; Mordon, Serge R.; Mathieu, D.; Maunoury, Vincent; Marechal, Xavier-Marie; Neviere, Remi; Wattel, Francis; Chopin, Claude

    1999-02-01

    Microcirculatory disorders of the gastrointestinal tract appear to be a major compound of the multiple organ dysfunction syndrome secondary to sepsis or septic shock. A better analysis of mucosal hypoperfusion in critically ill patients with sepsis may be helpful for the comprehension of this high mortality-associated syndrome. Fluorescence endoscopy has been recognized as a non-invasive method for both spatial and temporal evaluation of gastrointestinal mucosal perfusion. We performed this imaging technique during routine gastric endoscopy in patients with sepsis criteria. The study included gastric observation and appearance time of gastric fluorescence after an intravenous 10% sodium - fluorescein bolus. Qualitative analysis of high fluorescence areas was compared with mucosal blood flow measurements by laser - Doppler flowmetry. We concluded that the fluorescence endoscopic imaging in critically ill patients with sepsis may reveal spacial and temporal differences in the mucosal microcirculation distribution.

  19. Preliminary study on diffuse axonal injury by Fourier transform infrared spectroscopy histopathology imaging.

    Science.gov (United States)

    Yang, Tiantong; He, Guanglong; Zhang, Xiang; Chang, Lin; Zhang, Haidong; Ripple, Mary G; Fowler, David R; Li, Ling

    2014-01-01

    The objective of this study was to evaluate the application of Fourier transform infrared (FTIR) spectroscopy for detecting diffuse axonal injury (DAI) in a mouse model. Brain tissues from DAI mouse model were prepared with H&E, silver, and β-amyloid precursor protein (β-APP) immunohistochemistry stains and were also studied with FTIR. The infrared spectrum images showed high absorption of amide II in the subcortical white matter of the experimental mouse brain, while there was no obvious expression of amide II in the control mouse brain. The areas with high absorption of amide II were in the same distribution as the DAI region confirmed by the silver and β-APP studies. The result suggests that high absorption of amide II correlates with axonal injury. The use of FTIR imaging allows the biochemical changes associated with DAI pathologies to be detected in the tissues, thus providing an important adjunct method to the current conventional pathological diagnostic techniques.

  20. Magnetic resonance imaging in the assessment of revascularization in Kienbock's disease. A preliminary report.

    Science.gov (United States)

    Viegas, S F; Amparo, E

    1989-12-01

    A 25-year-old man with stage II Kienbock's disease of his left lunate underwent an initial period of immobilization. He was subsequently treated by ulnar lengthening, with a good outcome. Magnetic resonance imaging (MRI) was utilized to demonstrate the lack of improvement with cast immobilization and the revascularization that followed surgical treatment. This new application of MRI in cases of avascular necrosis of the lunate may be helpful in the early identification of revascularization.

  1. Biokinetics and imaging with the somatostatin receptor PET radioligand (68)Ga-DOTATOC: preliminary data.

    Science.gov (United States)

    Hofmann, M; Maecke, H; Börner, R; Weckesser, E; Schöffski, P; Oei, L; Schumacher, J; Henze, M; Heppeler, A; Meyer, J; Knapp, H

    2001-12-01

    Somatostatin (SMS) scintigraphy is widely used for the detection and staging of neuroendocrine tumours. Because of its superior imaging properties, there is growing interest in the use of positron emission tomography (PET) technology for SMS scintigraphy. This study addressed the production of gallium-68 DOTATOC, its biokinetics and its clinical performance in detecting SMS-positive tumours and metastases. A preparation protocol was developed, yielding 40% overall incorporation of (68)Ga into the peptide (DOTATOC). After column filtration, the radiochemical purity exceeded 98%. Eight patients with histologically verified carcinoid tumours were injected with 80-250 MBq of this tracer. PET acquisition was initiated immediately after administration and carried out until 3 h post injection. Images were quantitated using standardised uptake values and target to non-target ratios. Prior to (68)Ga-DOTATOC PET, all patients underwent indium-111 octreotide planar and single-photon emission tomographic (SPET) imaging. Arterial activity elimination was bi-exponential, with half-lives of 2.0 (+/-0.3) min and 48 (+/-7) min. No radioactive metabolites were detected within 4 h in serum. Maximal tumour activity accumulation was reached 70+/-20 min post injection. Kidney uptake averaged 68)Ga-DOTATOC PET identified 100%, whereas (111)In-octreotide planar and SPET imaging identified only 85%. Tumour to non-tumour ratios ranged from >3:1 for liver ((111)In-octreotide: 1.5:1) to 100:1 for CNS ((111)In-octreotide: 10:1). With (68)Ga-DOTATOC >30% additional lesions were detected. It is concluded that PET using (68)Ga-DOTATOC results in high tumour to non-tumour contrast and low kidney accumulation and yields higher detection rates as compared with (111)In-octreotide scintigraphy.

  2. Hyperpolarized {sup 3}He magnetic resonance imaging: Preliminary evaluation of phenotyping potential in chronic obstructive pulmonary disease

    Energy Technology Data Exchange (ETDEWEB)

    Mathew, Lindsay, E-mail: lmathew@imaging.robarts.ca [Imaging Research Laboratories, Robarts Research Institute, London (Canada); Department of Medical Biophysics, University of Western Ontario, London (Canada); Kirby, Miranda, E-mail: mkirby@imaging.robarts.ca [Imaging Research Laboratories, Robarts Research Institute, London (Canada); Department of Medical Biophysics, University of Western Ontario, London (Canada); Etemad-Rezai, Roya, E-mail: Roya.EtemadRezai@lhsc.on.ca [Department of Medical Imaging, University of Western Ontario (Canada); Wheatley, Andrew, E-mail: awheat@imaging.robarts.ca [Imaging Research Laboratories, Robarts Research Institute, London (Canada); McCormack, David G., E-mail: David.McCormack@lhsc.on.ca [Imaging Research Laboratories, Robarts Research Institute, London (Canada); Division of Respirology, Department of Medicine, University of Western Ontario, London (Canada); Lawson Health Research Institute, London (Canada); Parraga, Grace, E-mail: gep@imaging.robarts.ca [Imaging Research Laboratories, Robarts Research Institute, London (Canada); Department of Medical Biophysics, University of Western Ontario, London (Canada); Department of Medical Imaging, University of Western Ontario (Canada); Lawson Health Research Institute, London (Canada)

    2011-07-15

    Rationale and objectives: Emphysema and small airway obstruction are the pathological hallmarks of chronic obstructive pulmonary disease (COPD). The aim of this pilot study in a small group of chronic obstructive pulmonary disease (COPD) patients was to quantify hyperpolarized helium-3 ({sup 3}He) magnetic resonance imaging (MRI) functional and structural measurements and to explore the potential role for {sup 3}He MRI in detecting the lung structural and functional COPD phenotypes. Materials and methods: We evaluated 20 ex-smokers with stage I (n = 1), stage II (n = 9) and stage III COPD (n = 10). All subjects underwent same-day plethysmography, spirometry, {sup 1}H MRI and hyperpolarized {sup 3}He MRI at 3.0 T. {sup 3}He ventilation defect percent (VDP) was generated from {sup 3}He static ventilation images and {sup 1}H thoracic images and the {sup 3}He apparent diffusion coefficient (ADC) was derived from diffusion-weighted MRI. Results: Based on the relative contribution of normalized ADC and VDP, there was evidence of a predominant {sup 3}He MRI measurement in seven patients (n = 3 mainly ventilation defects or VDP dominant (VD), n = 4 mainly increased ADC or ADC dominant (AD)). Analysis of variance (ANOVA) showed significantly lower ADC for subjects with predominantly elevated VDP (p = 0.02 compared to subjects with predominantly elevated ADC; p = 0.008 compared to mixed group) and significantly decreased VDP for subjects with predominantly elevated ADC (p = 0.003, compared to mixed group). Conclusion: In this small pilot study, a preliminary analysis shows the potential for {sup 3}He MRI to categorize or phenotype COPD ex-smokers, providing good evidence of feasibility for larger prospective studies.

  3. Understanding God images and God concepts: Towards a pastoral hermeneutics of the God attachment experience

    Directory of Open Access Journals (Sweden)

    Victor Counted

    2015-03-01

    Full Text Available The author looks at the God image experience as an attachment relationship experience with God. Hence, arguing that the God image experience is borne originally out of a parent�child attachment contagion, in such a way that God is often represented in either secure or insecure attachment patterns. The article points out that insecure God images often develop head-to-head with God concepts in a believer�s emotional experience of God. On the other hand, the author describes God concepts as indicators of a religious faith and metaphorical standards for regulating insecure attachment patterns. The goals of this article, however, is to highlight the relationship between God images and God concepts, and to provide a hermeneutical process for interpreting and surviving the God image experience.Intradisciplinary and/or interdisciplinary implications: Given that most scholars within the discipline of Practical Theology discuss the subject of God images from cultural and theological perspectives, this article has discussed God images from an attachment perspective, which is a popular framework in psychology of religion. This is rare. The study is therefore interdisciplinary in this regards. The article further helps the reader to understand the intrapsychic process of the God image experience, and thus provides us with hermeneutical answers for dealing with the God image experience from methodologies grounded in Practical Theology and pastoral care.

  4. Destroying False Images of God: The Experiences of LGBT Catholics.

    Science.gov (United States)

    Deguara, Angele

    2017-04-10

    This article is about how lesbian, gay, bisexual, and trans (LGBT) Catholics imagine God and how images of God change in parallel with their self-image. The study is based on qualitative research with LGBT Catholics, most of whom are members of Drachma LGBTI in Malta or Ali d'Aquila in Palermo, Sicily. LGBT Catholics' image of God changes as they struggle to reconcile their religious and sexual identities and as they go through a process of "conversion" from deviants and sinners to loved children of God. One study participant compares his faith in God to peeling an onion: "With every layer one peels off, one destroys false images of God." Most study participants have moved away from the image of God as a bearded old man and father of creation and moved more toward a conception of God as love once identity conflicts are resolved.

  5. The preliminary results: Internal seismic velocity structure imaging beneath Mount Lokon

    Science.gov (United States)

    Firmansyah, Rizky; Nugraha, Andri Dian; Kristianto

    2015-04-01

    Historical records that before the 17th century, Mount Lokon had been dormant for approximately 400 years. In the years between 1350 and 1400, eruption ever recorded in Empung, came from Mount Lokon's central crater. Subsequently, in 1750 to 1800, Mount Lokon continued to erupt again and caused soil damage and fall victim. After 1949, Mount Lokon dramatically increased in its frequency: the eruption interval varies between 1 - 5 years, with an average interval of 3 years and a rest interval ranged from 8 - 64 years. Then, on June 26th, 2011, standby alert set by the Center for Volcanology and Geological Hazard Mitigation. Peak activity happened on July 4th, 2011 that Mount Lokon erupted continuously until August 28th, 2011. In this study, we carefully analyzed micro-earthquakes waveform and determined hypocenter location of those events. We then conducted travel time seismic tomographic inversion using SIMULPS12 method to detemine Vp, Vs and Vp/Vs ratio structures beneath Lokon volcano in order to enhance our subsurface geological structure. During the tomographic inversion, we started from 1-D seismic velocities model obtained from VELEST33 method. Our preliminary results show low Vp, low Vs, and high Vp/Vs are observed beneath Mount Lokon-Empung which are may be associated with weak zone or hot material zones. However, in this study we used few station for recording of micro-earthquake events. So, we suggest in the future tomography study, the adding of some seismometers in order to improve ray coverage in the region is profoundly justified.

  6. The preliminary results: Internal seismic velocity structure imaging beneath Mount Lokon

    Energy Technology Data Exchange (ETDEWEB)

    Firmansyah, Rizky, E-mail: rizkyfirmansyah@hotmail.com [Geophysical Engineering, Faculty of Mining and Petroleum Engineering, Institut Teknologi Bandung, Bandung, 40132 (Indonesia); Nugraha, Andri Dian, E-mail: nugraha@gf.itb.ac.id [Global Geophysical Group, Faculty of Mining and Petroleum Engineering, Institut Teknologi Bandung, Bandung, 40132 (Indonesia); Kristianto, E-mail: kris@vsi.esdm.go.id [Center for Volcanology and Geological Hazard Mitigation (CVGHM), Geological Agency, Bandung, 40122 (Indonesia)

    2015-04-24

    Historical records that before the 17{sup th} century, Mount Lokon had been dormant for approximately 400 years. In the years between 1350 and 1400, eruption ever recorded in Empung, came from Mount Lokon’s central crater. Subsequently, in 1750 to 1800, Mount Lokon continued to erupt again and caused soil damage and fall victim. After 1949, Mount Lokon dramatically increased in its frequency: the eruption interval varies between 1 – 5 years, with an average interval of 3 years and a rest interval ranged from 8 – 64 years. Then, on June 26{sup th}, 2011, standby alert set by the Center for Volcanology and Geological Hazard Mitigation. Peak activity happened on July 4{sup th}, 2011 that Mount Lokon erupted continuously until August 28{sup th}, 2011. In this study, we carefully analyzed micro-earthquakes waveform and determined hypocenter location of those events. We then conducted travel time seismic tomographic inversion using SIMULPS12 method to detemine Vp, Vs and Vp/Vs ratio structures beneath Lokon volcano in order to enhance our subsurface geological structure. During the tomographic inversion, we started from 1-D seismic velocities model obtained from VELEST33 method. Our preliminary results show low Vp, low Vs, and high Vp/Vs are observed beneath Mount Lokon-Empung which are may be associated with weak zone or hot material zones. However, in this study we used few station for recording of micro-earthquake events. So, we suggest in the future tomography study, the adding of some seismometers in order to improve ray coverage in the region is profoundly justified.

  7. The administration of psilocybin to healthy, hallucinogen-experienced volunteers in a mock-functional magnetic resonance imaging environment: a preliminary investigation of tolerability.

    Science.gov (United States)

    Carhart-Harris, Robin L; Williams, Tim M; Sessa, Ben; Tyacke, Robin J; Rich, Ann S; Feilding, Amanda; Nutt, David J

    2011-11-01

    This study sought to assess the tolerability of intravenously administered psilocybin in healthy, hallucinogen-experienced volunteers in a mock-magnetic resonance imaging environment as a preliminary stage to a controlled investigation using functional magnetic resonance imaging to explore the effects of psilocybin on cerebral blood flow and activity. The present pilot study demonstrated that up to 2 mg of psilocybin delivered as a slow intravenous injection produces short-lived but typical drug effects that are psychologically and physiologically well tolerated. With appropriate care, this study supports the viability of functional magnetic resonance imaging work with psilocybin.

  8. Our experience in the diagnosis of intraocular tumours by a B-scan computerized system and angiodynography (Doppler). Preliminary results.

    Science.gov (United States)

    Falco, L; Esente, S; Fanfani, S; Pasarelli, N; Utari, S

    1992-01-01

    The authors compare the ultrasound diagnostic results of intraocular tumours by A/B-scans (Sonomed B 3000, Sonocare, Sonovision STT-100) with images obtained using computerized B-scan (Sonocare, Sonovision STT-100, Acoustic Tissue Typing ATT) and angiodynopgraphy systems (Quantum Philips). The Sonovision uses a computerized ultrasound spectrum analysis to assess the probability that a given lesion is a certain tumour, rather than another. The ATT system provides diagnostic probability for type B and type E melanoma, for haemangioma and metastatic carcinoma. The Quantum ultrasound equipment was developed for studying the heart and the major blood vessels. It is a colour Doppler that simplifies the Doppler technique, allowing it to study small anatomical parts such as tumour-like lesions of the eye. The Doppler technique ascertains the presence and the velocity of blood flow in the tumours. In presenting the preliminary results with the new techniques the authors are aware that the ATT system is not designed for some of the lesions under study (melanomas after conservative radiotherapy).

  9. Preliminary study of kaonic deuterium X-rays by the SIDDHARTA experiment at DAΦNE

    Energy Technology Data Exchange (ETDEWEB)

    Bazzi, M. [INFN, Laboratori Nazionali di Frascati, C.P. 13, Via E. Fermi 40, I-00044 Frascati (Roma) (Italy); Beer, G. [Department of Physics and Astronomy, University of Victoria, P.O. Box 3055, Victoria BC V8W3P6 (Canada); Berucci, C. [Stefan-Meyer-Institut für subatomare Physik, Boltzmanngasse 3, 1090 Wien (Austria); INFN, Laboratori Nazionali di Frascati, C.P. 13, Via E. Fermi 40, I-00044 Frascati (Roma) (Italy); Bombelli, L. [Politecnico di Milano, Dipartimento di Elettronica e Informazione, Piazza L. da Vinci 32, I-20133 Milano (Italy); Bragadireanu, A.M. [INFN, Laboratori Nazionali di Frascati, C.P. 13, Via E. Fermi 40, I-00044 Frascati (Roma) (Italy); IFIN-HH, Institutul National pentru Fizica si Inginerie Nucleara Horia Hulubei, Reactorului 30, Magurele (Romania); Cargnelli, M., E-mail: michael.cargnelli@oaaw.ac.at [Stefan-Meyer-Institut für subatomare Physik, Boltzmanngasse 3, 1090 Wien (Austria); Curceanu, C.; D' Uffizi, A. [INFN, Laboratori Nazionali di Frascati, C.P. 13, Via E. Fermi 40, I-00044 Frascati (Roma) (Italy); Fiorini, C.; Frizzi, T. [Politecnico di Milano, Dipartimento di Elettronica e Informazione, Piazza L. da Vinci 32, I-20133 Milano (Italy); Ghio, F. [INFN Sezione di Roma I and Instituto Superiore di Sanita, I-00161 Roma (Italy); Guaraldo, C. [INFN, Laboratori Nazionali di Frascati, C.P. 13, Via E. Fermi 40, I-00044 Frascati (Roma) (Italy); Hayano, R. [University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo (Japan); Iliescu, M. [INFN, Laboratori Nazionali di Frascati, C.P. 13, Via E. Fermi 40, I-00044 Frascati (Roma) (Italy); Ishiwatari, T. [Stefan-Meyer-Institut für subatomare Physik, Boltzmanngasse 3, 1090 Wien (Austria); Iwasaki, M. [RIKEN, Institute of Physical and Chemical Research, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); and others

    2013-06-03

    The study of the K{sup ¯}N system at very low energies plays a key role for the understanding of the strong interaction between hadrons in the strangeness sector. At the DAΦNE electron–positron collider of Laboratori Nazionali di Frascati we studied kaonic atoms with Z=1 and Z=2, taking advantage of the low-energy charged kaons from Φ-mesons decaying nearly at rest. The SIDDHARTA experiment used X-ray spectroscopy of the kaonic atoms to determine the transition yields and the strong interaction induced shift and width of the lowest experimentally accessible level (1s for H and D and 2p for He). Shift and width are connected to the real and imaginary part of the scattering length. To disentangle the isospin dependent scattering lengths of the antikaon–nucleon interaction, measurements of K{sup −}p and of K{sup −}d are needed. We report here on an exploratory deuterium measurement, from which a limit for the yield of the K-series transitions was derived: Y(K{sub tot})<0.0143 and Y(K{sub α})<0.0039 (CL 90%). Also, the upcoming SIDDHARTA-2 kaonic deuterium experiment is introduced.

  10. Preliminary study of kaonic deuterium X-rays by the SIDDHARTA experiment at DAΦNE.

    Science.gov (United States)

    Bazzi, M; Beer, G; Berucci, C; Bombelli, L; Bragadireanu, A M; Cargnelli, M; Curceanu Petrascu, C; Dʼuffizi, A; Fiorini, C; Frizzi, T; Ghio, F; Guaraldo, C; Hayano, R; Iliescu, M; Ishiwatari, T; Iwasaki, M; Kienle, P; Levi Sandri, P; Longoni, A; Marton, J; Okada, S; Pietreanu, D; Ponta, T; Romero Vidal, A; Sbardella, E; Scordo, A; Shi, H; Sirghi, D L; Sirghi, F; Tatsuno, H; Tudorache, A; Tudorache, V; Vazquez Doce, O; Widmann, E; Zmeskal, J

    2013-06-03

    The study of the [Formula: see text] system at very low energies plays a key role for the understanding of the strong interaction between hadrons in the strangeness sector. At the DAΦNE electron-positron collider of Laboratori Nazionali di Frascati we studied kaonic atoms with [Formula: see text] and [Formula: see text], taking advantage of the low-energy charged kaons from Φ-mesons decaying nearly at rest. The SIDDHARTA experiment used X-ray spectroscopy of the kaonic atoms to determine the transition yields and the strong interaction induced shift and width of the lowest experimentally accessible level (1s for H and D and 2p for He). Shift and width are connected to the real and imaginary part of the scattering length. To disentangle the isospin dependent scattering lengths of the antikaon-nucleon interaction, measurements of [Formula: see text] and of [Formula: see text] are needed. We report here on an exploratory deuterium measurement, from which a limit for the yield of the K-series transitions was derived: [Formula: see text] and [Formula: see text] (CL 90%). Also, the upcoming SIDDHARTA-2 kaonic deuterium experiment is introduced.

  11. Preliminary investigation of relations between young students' self-regulatory strategies and their metacognitive experiences.

    Science.gov (United States)

    Dermitzaki, Irini

    2005-12-01

    The present study investigated second-graders' self-regulative behav ior during task engagement and its relations to performance and to students' on-line metacognitive experiences. Participants were 25 individually examined Greek second graders (13 boys and 12 girls; M age: 7.6 yr., SD = 0.2). Students' use of cognitive, metacognitive, and motivational regulatory strategies while performing a cognitive task were directly observed and recorded by two independent observers. Students' task-specific performance was also evaluated. Finally, students' feeling of satisfaction with the solution produced, their estimate of effort expenditure, and estimate of the solution's correctness were assessed. Analysis showed these second grade students' use of self-regulatory strategies and feeling of satisfaction were significantly associated with their performance. However, metacognitive experiences reported after the solution were only slightly related to the students' actual self-regulative behavior during the task, implying that the relations of students' regulatory efforts with their metacognitive processes are still developing at such a young age.

  12. Evaluation of the diagnostic performance of infrared imaging of the breast: a preliminary study

    Directory of Open Access Journals (Sweden)

    Wu Yuh-Ming

    2010-01-01

    Full Text Available Abstract Background The study was conducted to investigate the diagnostic performance of infrared (IR imaging of the breast using an interpretive model derived from a scoring system. Methods The study was approved by the Institutional Review Board of our hospital. A total of 276 women (mean age = 50.8 years, SD 11.8 with suspicious findings on mammograms or ultrasound received IR imaging of the breast before excisional biopsy. The interpreting radiologists scored the lesions using a scoring system that combines five IR signs. The ROC (receiver operating characteristic curve and AUC (area under the ROC curve were analyzed by the univariate logistic regression model for each IR sign and an age-adjusted multivariate logistic regression model including 5 IR signs. The cut-off values and corresponding sensitivity, specificity, Youden's Index (Index = sensitivity+specificity-1, positive predictive value (PPV, negative predictive value (NPV were estimated from the age-adjusted multivariate model. The most optimal cut-off value was determined by the one with highest Youden's Index. Results For the univariate model, the AUC of the ROC curve from five IR signs ranged from 0.557 to 0.701, and the AUC of the ROC from the age-adjusted multivariate model was 0.828. From the ROC derived from the multivariate model, the sensitivity of the most optimal cut-off value would be 72.4% with the corresponding specificity 76.6% (Youden's Index = 0.49, PPV 81.3% and NPV 66.4%. Conclusions We established an interpretive age-adjusted multivariate model for IR imaging of the breast. The cut-off values and the corresponding sensitivity and specificity can be inferred from the model in a subpopulation for diagnostic purpose. Trial Registration NCT00166998.

  13. Quantitative dynamic contrast-enhanced MR imaging analysis of complex adnexal masses: a preliminary study.

    Science.gov (United States)

    Thomassin-Naggara, Isabelle; Balvay, Daniel; Aubert, Emilie; Daraï, Emile; Rouzier, Roman; Cuenod, Charles A; Bazot, Marc

    2012-04-01

    To evaluate the ability of quantitative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to differentiate malignant from benign adnexal tumours. Fifty-six women with 38 malignant and 18 benign tumours underwent MR imaging before surgery for complex adnexal masses. Microvascular parameters were extracted from high temporal resolution DCE-MRI series, using a pharmacokinetic model in the solid tissue of adnexal tumours. These parameters were tissue blood flow (F(T)), blood volume fraction (Vb), permeability-surface area product (PS), interstitial volume fraction (Ve), lag time (Dt) and area under the enhancing curve (rAUC). Area under the receiver operating curve (AUROC) was calculated as a descriptive tool to assess the overall discrimination of parameters. Malignant tumours displayed higher F(T), Vb, rAUC and lower Ve than benign tumours (P < 0.0001, P = 0.0006, P = 0.04 and P = 0.0002, respectively). F(T) was the most relevant factor for discriminating malignant from benign tumours (AUROC = 0.86). Primary ovarian invasive tumours displayed higher F(T) and shorter Dt than borderline tumours. Malignant adnexal tumours with associated peritoneal carcinomatosis at surgery displayed a shorter Dt than those without peritoneal carcinomatosis at surgery (P = 0.01). Quantitative DCE-MRI is a feasible and accurate technique to differentiate malignant from benign adnexal tumours and could potentially help oncologists with management decisions. Quantitative DCE MR imaging allows accurate differentiation between malignant and benign tumours. Quantitative DCE MRI may help predict peritoneal carcinomatosis associated with ovarian tumors. Quantitative DCE MRI helps distinguish between invasive and borderline primary ovarian tumours.

  14. 3-D Tomographic Imaging of the Chicxulub Impact Crater: Preliminary Results From EW#0501

    Science.gov (United States)

    Surendra, A. T.; Barton, P. J.; Vermeesch, P. M.; Morgan, J. V.; Warner, M. R.; Gulick, S. P.; Christeson, G. L.; Urrutia-Fucugauchi, J.; Rebolledo-Vieyra, M.; Melosh, H. J.; McDonald, M. A.; Goldin, T.; Mendoza, K.

    2005-05-01

    The Chicxulub impact structure provides a unique opportunity to investigate the sub-surface morphology of large craters on Earth and other planets. The structure of the crater interior is still poorly known and there is much uncertainty over the sequence of events by which these large craters form and the magnitude of the subsequent catastrophic environmental effects. In early 2005, a reflection-refraction survey aboard the R/V Maurice Ewing imaged the deep structure of the Chicxulub impact. We present wide-angle data collected by a 3-D grid of 50 ocean bottom seismometers (OBSs), 86 three-component land stations and a 6 km long hydrophone streamer. The OBS grid, designed to image the peak ring and underlying structure of the northwestern quadrant of the crater, recorded shots from several seismic profiles in various orientations. Many of these profiles extended past the crater rim imaging to the base of the crust. Travel-time picks from this dataset, combined with existing 1996 data, will be inverted using the JIVE3-D tomographic inversion program to create a fully 3-D velocity model of the crater interior. The interpretation of the velocity model will focus on the morphology of the peak ring and the central uplift, and the distribution of breccia and suevite (an impact related breccia/melt) in the centre of the crater. We will calculate the Poisson's ratio for different areas of the crater using both the P-wave velocity model and S-wave arrivals, including those from the 1996 land station data. Comparisons of these values with measurements on the Yaxcopoil-1 core taken from within the crater provide ground-truth for our tomographic model. The contrast in Poisson's ratio between areas of suevite and the surrounding rock further constrain the distribution of breccia and suevite.

  15. AS30D Model of Hepatocellular Carcinoma: Tumorigenicity and Preliminary Characterization by Imaging, Histopathology, and Immunohistochemistry

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, Scott M. [Mayo Clinic, Medical Scientist Training Program (United States); Callstrom, Matthew R. [Mayo Clinic, Department of Radiology (United States); Knudsen, Bruce [Mayo Clinic, Department of Laboratory Medicine and Pathology (United States); Anderson, Jill L. [Mayo Clinic, Division of Physiology and Bioengineering (United States); Butters, Kim A.; Grande, Joseph P. [Mayo Clinic, Department of Laboratory Medicine and Pathology (United States); Roberts, Lewis R. [Mayo Clinic, Division of Gastroenterology and Hepatology (United States); Woodrum, David A., E-mail: woodrum.david@mayo.edu [Mayo Clinic, Department of Radiology (United States)

    2013-02-15

    This study was designed to determine the tumorigenicity of the AS30D HCC cell line following orthotopic injection into rat liver and preliminarily characterize the tumor model by both magnetic resonance imaging (MRI) and ultrasound (US) as well as histopathology and immunohistochemistry.MaterialsAS30D cell line in vitro proliferation was assessed by using MTT assay. Female rats (N = 5) underwent injection of the AS30D cell line into one site in the liver. Rats subsequently underwent MR imaging at days 7 and 14 to assess tumor establishment and volume. One rat underwent US of the liver at day 7. Rats were euthanized at day 7 or 14 and livers were subjected to gross, histopathologic (H and E), and immunohistochemical (CD31) analysis to assess for tumor growth and neovascularization. AS30D cell line demonstrated an in vitro doubling time of 33.2 {+-} 5.3 h. MR imaging demonstrated hyperintense T2-weighted and hypointense T1-weighted lesions with tumor induction in five of five and three of three sites at days 7 and 14, respectively. The mean (SD) tumor volume was 126.1 {+-} 36.2 mm{sup 3} at day 7 (N = 5). US of the liver demonstrated a well-circumscribed, hypoechoic mass and comparison of tumor dimensions agreed well with MRI. Analysis of H and E- and CD31-stained sections demonstrated moderate-high grade epithelial tumors with minimal tumor necrosis and evidence of diffuse intratumoral and peritumoral neovascularization by day 7. AS30D HCC cell line is tumorigenic following orthotopic injection into rat liver and can be used to generate an early vascularizing, slower-growing rat HCC tumor model.

  16. Vocabulary Length Experiments for Binary Image Classification Using BOV Approach

    Directory of Open Access Journals (Sweden)

    S.P.Vimal

    2013-12-01

    Full Text Available Bag-of-Visual-words (BoV approach to image classif ication is popular among computer vision scientists . The visual words come from the visual vocabulary wh ich is constructed using the key points extracted f rom the image database. Unlike the natural language, th e length of such vocabulary for image classificatio n is task dependent. The visual words capture the local invariant features of the image. The region of imag e over which a visual word is constrained forms the s patial content for the visual word. Spatial pyramid representation of images is an approach to handle s patial information. In this paper, we study the rol e of vocabulary lengths for the levels of a simple two l evel spatial pyramid to perform binary classificati ons. Two binary classification problems namely to detect the presence of persons and cars are studied. Rele vant images from PASCAL dataset are being used for the l earning activities involved in this work

  17. Predictive models applied to groundwater level forecasting: a preliminary experience on the alluvial aquifer of the Magra River (Italy).

    Science.gov (United States)

    Brozzo, Gianpiero; Doveri, Marco; Lelli, Matteo; Scozzari, Andrea

    2010-05-01

    Computer-based decision support systems are getting a growing interest for water managing authorities and water distribution companies. This work discusses a preliminary experience in the application of computational intelligence in a hydrological modeling framework, regarding the study area of the alluvial aquifer of the Magra River (Italy). Two sites in the studied area, corresponding to two distinct groups of wells (Battifollo and Fornola) are managed by the local drinkable water distribution company (ACAM Acque), which serves the area of La Spezia, on the Ligurian coast. Battifollo has 9 wells with a total extraction rate of about 240 liters per second, while Fornola has 44 wells with an extraction rate of about 900 liters per second. Objective of this work is to make use of time series coming from long-term monitoring activities in order to assess the trend of the groundwater level with respect to a set of environmental and exploitation parameters; this is accomplished by the experimentation of a suitable model, eligible to be used as a predictor. This activity moves on from the modeling of the system behavior, based on a set of Input/Output data, in order to characterize it without necessarily a prior knowledge of any deterministic mechanism (system identification). In this context, data series collected by continuous hydrological monitoring instrumentation installed in the studied sites, together with meteorological and water extraction data, have been analyzed in order to assess the applicability and performance of a predictive model of the groundwater level. A mixed approach (both data driven and process-based) has been experimented on the whole dataset relating to the last ten years of continuous monitoring activity. The system identification approach presented here is based on the integration of an adaptive technique based on Artificial Neural Networks (ANNs) and a blind deterministic identification approach. According to this concept, the behavior of

  18. Note: Upgrade of electron cyclotron emission imaging system and preliminary results on HL-2A tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, M., E-mail: jiangm@swip.ac.cn; Shi, Z. B.; Zhong, W. L.; Chen, W.; Liu, Z. T.; Ding, X. T.; Yang, Q. W.; Zhang, B. Y.; Shi, P. W.; Liu, Y.; Fu, B. Z.; Xu, Y. [Southwestern Institute of Physics, P.O. Box 432, Chengdu 610041 (China); Domier, C. W.; Luhmann, N. C. [Department of Electrical and Computer Engineering, University of California, Davis, California 95616 (United States); Yang, Z. C. [School of Physics and Chemistry, Xihua University, Chengdu 610039 (China)

    2015-07-15

    The electron cyclotron emission imaging system on the HL-2A tokamak has been upgraded to 24 (poloidally) × 16 (radially) channels based on the previous 24 × 8 array. The measurement region can be flexibly shifted due to the independence of the two local oscillator sources, and the field of view can be adjusted easily by changing the position of the zoom lenses. The temporal resolution is about 2.5 μs and the achievable spatial resolution is 1 cm. After laboratory calibration, it was installed on HL-2A tokamak in 2014, and the local 2D mode structures of MHD activities were obtained for the first time.

  19. Percutaneous local ablation of unifocal subclinical breast cancer: clinical experience and preliminary results of cryotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Manenti, Guglielmo; Perretta, Tommaso; Gaspari, Eleonora; Pistolese, Chiara A.; Scarano, Lia; Cossu, Elsa; Simonetti, Giovanni; Masala, Salvatore [University Hospital ' ' Tor Vergata' ' , Department of Diagnostic Imaging and Interventional Radiology, Molecular Imaging and Radiotherapy, Rome (Italy); Bonanno, Elena [University Hospital ' ' Tor Vergata' ' , Department of Biopathology, Rome (Italy); Buonomo, Oreste C.; Petrella, Giuseppe [University Hospital ' ' Tor Vergata' ' , Department of General Surgery Division, Rome (Italy)

    2011-11-15

    To assess the ablative effectiveness, the oncological and cosmetic efficacy of image-guided percutaneous cryoablation in the treatment of single breast nodules with subclinical dimensions after identification with ultrasonography (US), mammography, magnetic resonance (MRI) and characterization by vacuum assisted biopsy. Fifteen women with a mean age of 73 {+-} 5 years (range 64-82 years) and lesion diameter of 8 {+-} 4 mm were undergoing cryotherapy technology with a single probe under US-guidance associated with intra-procedural lymph-node mapping and excision of the sentinel node. All the patients underwent surgical resection (lumpectomy) from 30 to 45 days after the percutaneous ablation. The iceball size generated by the cryoprobe during the procedure at minus 40 C was 16 x 41 mm. In 14 of the 15 patients was observed a complete necrosis of the cryo-ablated lesion both in post-procedural MRI follow-up and anatomo-pathological evaluation after surgical resection. In one case there was a residual disease in post-procedural MRI and postoperative histological examination, probably justified by an incorrect positioning of the probe. The percutaneous cryoablation as a ''minimally invasive'' technique can provide excellent oncological and cosmetic results on selected cases handled by experienced operators by using the tested devices. (orig.)

  20. CT enterography: a preliminary experience in the evaluation of small bowel diseases

    Energy Technology Data Exchange (ETDEWEB)

    Costa-Silva, Luciana [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Medical School. Dept. of Supplementary Propedeutics; Martins, Tatiana [Ecoar Medicina Diagnostica, Belo Horizonte, MG (Brazil); Passos, Maria do Carmo Friche [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Medical School. Dept. of Medical Practice

    2010-09-15

    Objective: the present study was aimed at demonstrating the value of computed tomography enterography (CT enterography) and how this imaging method can be useful in the diagnostic elucidation and assessment of patients with small bowel diseases. Materials and methods: retrospective evaluation of 35 patients submitted to CT enterography in a 16-row multidetector CT equipment from May/2008 to March/2009. All the patients received intravenous and neutral oral iodinated contrast agents (polyethylene glycol). Main indications were: Crohn's disease, diarrhea of undetermined origin and suspicion of neoplasia. Results: a good correlation was observed between CT enterography findings and clinical, laboratory and endoscopic data related to the disease activity in patients with Crohn's disease. In 15 cases alterations compatible with Crohn's disease were identified, nine of them suggesting disease activity. A diagnosis was achieved in the majority of the patients with diarrhea. Carcinoid tumors were identified in two patients. Conclusion: CT enterography is a simple and effective method in the evaluation of inflammatory/neoplastic small bowel diseases, particularly in cases of Crohn's disease, indicating disease activity. One of the main advantages of this method is the possibility of evaluating associated mesenteric and extraintestinal alterations (author)

  1. Spectral CT evaluation of interstitial brachytherapy in pancreatic carcinoma xenografts: preliminary animal experience

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Shudong [Jiangsu University, Department of Radiology, The Affiliated Renmin Hospital, Zhenjiang, Jiangsu (China); Shanghai Jiao tong University, School of Medicine, Department of Radiology, Ruijin Hospital, Shanghai (China); Huang, Wei; Song, Qi; Lin, Xiaozhu; Wang, Zhongmin; Chen, Kemin [Shanghai Jiao tong University, School of Medicine, Department of Radiology, Ruijin Hospital, Shanghai (China); Chen, Yerong [Jiangsu University, Department of Radiology, The Affiliated Renmin Hospital, Zhenjiang, Jiangsu (China)

    2014-09-15

    We sought to evaluate the capability of spectral CT to detect the therapeutic response to {sup 125}I interstitial brachytherapy in a pancreatic carcinoma xenograft nude mouse model. Twenty mice bearing SWl990 human pancreatic cancer cell xenografts were randomly separated into two groups: experimental (n = 10; 1.0 mCi) and control (n = 10; 0 mCi). After a two-week treatment, spectral CT was performed. Contrast-to-noise ratio (CNR) and iodine concentration (IC) in the lesions were measured and normalized to the muscle tissue, and nIC CD31 immunohistochemistry was used to measure microvessel density (MVD). The relationships between the nIC and MVD of the tumours were analysed. The nIC of the experimental group was significantly lower than that of the control group during the multiphase examination. A significant difference in the MVD was observed between the two groups (P <0.001). The nIC values of the three-phase scans have a certain positive correlation with MVD (r = 0.57, p < 0.0001; r = 0.48, p = 0.002; r = 0.63, p = 0.0017 in the 10, 25, and 60 s phase, respectively). Spectral CT can be a useful non-invasive imaging modality in evaluating the therapeutic effect of {sup 125}I interstitial brachytherapy to a pancreatic carcinoma. (orig.)

  2. Laparoscopic microwave ablation and enucleation of small renal masses: preliminary experience.

    Science.gov (United States)

    Muto, Giovanni; Castelli, Emanuele; Migliari, Roberto; D'Urso, Leonardo; Coppola, Pietro; Collura, Devis

    2011-07-01

    Advancements in imaging and laparoscopy have led to the expansion of minimally invasive techniques in the ablation of small renal masses (SRMs). We report the results of a study aimed at assessing the efficacy of thermoablative microwave (MW) effects on SRMs and the haemostatic as well as necrotic MW effects on the parenchyma surrounding the neoplasm. From November 2008 to October 2010, 10 patients with SRMs underwent laparoscopy-guided Tru-Cut biopsy, MW tumour ablation, and enucleation. Mean age was 66 yr (range: 46-84 yr). Mean renal tumour diameter was 2.75 cm (range: 1.3-4.2 cm). MW antennas were applied one to three times depending on tumour volume, location, and shape. After MW thermoablation, laparoscopic enucleation was performed to evaluate the histopathologic and haemostatic effects of MW. The mean MW antenna application time was 14.1 min (range: 4-30 min). Enucleation did not require renal pedicle clamping in any of the cases because no significant bleeding took place. Preablation pathology revealed clear cell renal carcinoma of Fuhrman grade I-II in all cases. Postablation pathology showed extensive coagulative necrosis without skipped tumour areas. No intra- or postoperative complications were reported. Histopathologic effects on SRMs provide consistent proof of principle for future studies.

  3. Ultrasound-guided percutaneous drainage of meniscal cysts: preliminary clinical experience

    Energy Technology Data Exchange (ETDEWEB)

    MacMahon, P.J. [Department of Radiology, Cappagh National Orthopaedic Hospital, Finglas, Dublin (Ireland)]. E-mail: petermacmahon@yahoo.com; Brennan, D.D. [Department of Radiology, Cappagh National Orthopaedic Hospital, Finglas, Dublin (Ireland); Duke, D. [Department of Radiology, Cappagh National Orthopaedic Hospital, Finglas, Dublin (Ireland); Forde, S. [Department of Radiology, Cappagh National Orthopaedic Hospital, Finglas, Dublin (Ireland); Eustace, S.J. [Department of Radiology, Cappagh National Orthopaedic Hospital, Finglas, Dublin (Ireland)

    2007-07-15

    Aim: To evaluate the efficacy of ultrasound-guided percutaneous drainage of symptomatic meniscal cysts. Materials and methods: Patients with lateral knee joint tenderness and swelling and confirmed meniscal cyst on magnetic resonance imaging (MRI) were consecutively enrolled for ultrasound-guided percutaneous cyst aspiration. Cysts were injected with local anaesthetic and steroid before completion of procedure. All 18 patients (all male, average age 33 years) were subsequently followed up (average time 10 months) and meniscal cyst symptoms assessed by questionnaire. Fischer's exact test used to analyse the data. Results: In every case the procedure was well tolerated, and each patient indicated that they would be willing to have a repeat procedure in the future. Ten patients reported complete resolution of symptoms secondary to therapeutic cyst aspiration and had resumed participation in high-performance sport. Two patients reported a satisfactory sustained response, reporting only occasional 'twinges of pain'. In the remaining six patients, symptoms returned after an initial pain-free period. The pain-free period ranged from 1-8 weeks. In this study, patient outcome did not significantly correlate with any meniscal cyst characteristic. Conclusion: Ultrasound-guided percutaneous aspiration of meniscal cysts is a well-tolerated, simple, and safe procedure. In this small patient series, it was associated with positive early results with favourable outcomes in the mid to long-term. It should be considered in patients unsuitable for surgical debridement or as an interim therapy if surgery is delayed or postponed.

  4. Aespoe Pillar Stability Experiment. Final coupled 3D thermo-mechanical modeling. Preliminary particle mechanical modeling

    Energy Technology Data Exchange (ETDEWEB)

    Wanne, Toivo; Johansson, Erik; Potyondy, David [Saanio and Riekkola Oy, Helsinki (Finland)

    2004-02-01

    SKB is planning to perform a large-scale pillar stability experiment called APSE (Aespoe Pillar Stability Experiment) at Aespoe HRL. The study is focused on understanding and control of progressive rock failure in hard crystalline rock and damage caused by high stresses. The elastic thermo-mechanical modeling was carried out in three dimensions because of the complex test geometry and in-situ stress tensor by using a finite-difference modeling software FLAC3D. Cracking and damage formation were modeled in the area of interest (pillar between two large scale holes) in two dimensions by using the Particle Flow Code (PFC), which is based on particle mechanics. FLAC and PFC were coupled to minimize the computer resources and the computing time. According to the modeling the initial temperature rises from 15 deg C to about 65 deg C in the pillar area during the heating period of 120 days. The rising temperature due to thermal expansion induces stresses in the pillar area and after 120 days heating the stresses have increased about 33% from the excavation induced maximum stress of 150 MPa to 200 MPa in the end of the heating period. The results from FLAC3D model showed that only regions where the crack initiation stress has exceeded were identified and they extended to about two meters down the hole wall. These could be considered the areas where damage may occur during the in-situ test. When the other hole is pressurized with a 0.8 MPa confining pressure it yields that 5 MPa more stress is needed to damage the rock than without confining pressure. This makes the damaged area in some degree smaller. High compressive stresses in addition to some tensile stresses might induce some AE (acoustic emission) activity in the upper part of the hole from the very beginning of the test and are thus potential areas where AE activities may be detected. Monitoring like acoustic emissions will be measured during the test execution. The 2D coupled PFC-FLAC modeling indicated that

  5. E-Commerce Experiences in the Real Estate Industry: a preliminary study in regional Queensland

    Directory of Open Access Journals (Sweden)

    Jeanette Van Akkeren

    2003-05-01

    Full Text Available Computer systems have become commonplace in most SMEs and technology is increasingly becoming a part of doing business. In recent years, the Internet has become readily available to businesses; consequently there has been growing pressure on SMEs to take up e-commerce. However, e-commerce is perceived by many as being unproven in terms of business benefit. This research aims to determine what, if any, benefits are derived from assimilating e-commerce technologies into SME business processes. This paper presents three in-depth case studies from the Real Estate industry in a regional setting. Overall, findings were positive and identified the following experiences: enhanced business efficiencies, cost benefits, improved customer interactions and increased business return on investment.

  6. Preliminary results of the Artemia salina experiments in biostack on LDEF

    Science.gov (United States)

    Graul, E. H.; Ruether, W.; Hiendl, C. O.

    1992-01-01

    The mosaic egg of the brine shrimp, Artemia salina, resting in blastula or gastrula state represents a system that during further development, proceeds without any further development to the larval stage, the free swimming nauplius. Therefore, injury to a single cell of the egg will be manifest in the larvae. In several experiments, it was shown that the passage of a single heavy ion through the shrimp egg damaged a cellular area large enough to disturb either embryogenesis or further development of the larvae, or the integrity of the adult individual. Emergence from the egg shell was heavily disturbed by the heavy ions as was hatching. Additional late effects, due to a hit by a heavy ion, are delayed of growth and of sexual maturity, and reduced fertility. Anomalies in the body and the extremities could be observed more frequently for the nauplii which had developed from eggs hit by heavy ions.

  7. Do medical images aid understanding and recall of medical information? An experimental study comparing the experience of viewing no image, a 2D medical image and a 3D medical image alongside a diagnosis.

    Science.gov (United States)

    Phelps, Emma Elizabeth; Wellings, Richard; Griffiths, Frances; Hutchinson, Charles; Kunar, Melina

    2017-06-01

    This study compared the experience of viewing 3D medical images, 2D medical images and no image presented alongside a diagnosis. We conducted two laboratory experiments, each with 126 healthy participants. Participants heard three diagnoses; one accompanied by 3D medical images, one accompanied by 2D medical images and one with no image. Participants completed a questionnaire after each diagnosis rating their experience. In Experiment 2, half of the participants were informed that image interpretation can be susceptible to errors. Participants preferred to view 3D images alongside a diagnosis (pmedical images may aid patient understanding, recall and trust in medical information. Medical images may be a powerful resource for patients that could be utilised by clinicians during consultations. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  8. Hoe Creek II field experiment on underground coal gasification, preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Aiman, W.R.; Thorsness, C.B.; Hill, R.W.; Rozsa, R.B.; Cena, R.; Gregg, D.W.; Stephens, D.R.

    1978-02-27

    A second in-situ coal gasification experiment was performed by Lawrence Livermore Laboratory at Hoe Creek in Wyoming. The Linked Vertical Wells scheme for in-situ coal gasification was used. The experiment took 100 days for air flow testing, reverse combustion linking, forward combustion gasification, and post-burn steam flow. Air was used for gasification except for a 2-day test with oxygen and steam. Reverse combustion linking took 14 days at 1.6 m/day. Air requirements for linking were 0.398 Mgmol per meter of link assuming a single direct link. The coal pyrolysed during linking was 17 m/sup 3/, which corresponds to a single link 1.0 m in diameter. There was, however, strong evidence of at least two linkage paths. The detected links stayed below the 3 m level in the 7.6 coal seam; however, the product flow from the forward-burn gasification probably followed the coal-overburden interface not the reverse burn channels at the 3 m level. A total of 232 Mgmols (194 Mscf) of gas was produced with heating value above 125 kJ/mol (140 Btu/scf) for significant time periods and an average of 96 kJ/mol (108 Btu/scf). During the oxygen-steam test the heating value was above 270 kJ/gmol (300 Btu/scf) twice and averaged 235 kJ/gmol (265 Btu/scf). The coal recovery was 1310 m/sup 3/ (1950 ton). Gasification was terminated because of decreasing product quality not because of burn through. The product quality decreased because of increasing underground heat loss.

  9. Quantitative dynamic contrast-enhanced MR imaging analysis of complex adnexal masses: a preliminary study

    Energy Technology Data Exchange (ETDEWEB)

    Thomassin-Naggara, Isabelle [Hopital Tenon, Assistance Publique-Hopitaux de Paris, Department of Radiology, Paris (France); Laboratoire de recherche en imagerie - UMR 970 INSERM - Universite Rene Descartes, Paris (France); Service de Radiologie, Hopital Tenon, Paris (France); Balvay, Daniel [Laboratoire de recherche en imagerie - UMR 970 INSERM - Universite Rene Descartes, Paris (France); Aubert, Emilie; Bazot, Marc [Hopital Tenon, Assistance Publique-Hopitaux de Paris, Department of Radiology, Paris (France); Darai, Emile; Rouzier, Roman [Hopital Tenon, Assistance Publique-Hopitaux de Paris, Department of Gynaecology-Obstetrics, Paris (France); Cuenod, Charles A. [Laboratoire de recherche en imagerie - UMR 970 INSERM - Universite Rene Descartes, Paris (France); Hopital Europeen Georges Pompidou (HEGP), Department of Radiology, Paris (France)

    2012-04-15

    To evaluate the ability of quantitative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to differentiate malignant from benign adnexal tumours. Fifty-six women with 38 malignant and 18 benign tumours underwent MR imaging before surgery for complex adnexal masses. Microvascular parameters were extracted from high temporal resolution DCE-MRI series, using a pharmacokinetic model in the solid tissue of adnexal tumours. These parameters were tissue blood flow (F{sub T}), blood volume fraction (Vb), permeability-surface area product (PS), interstitial volume fraction (Ve), lag time (Dt) and area under the enhancing curve (rAUC). Area under the receiver operating curve (AUROC) was calculated as a descriptive tool to assess the overall discrimination of parameters. Malignant tumours displayed higher F{sub T}, Vb, rAUC and lower Ve than benign tumours (P < 0.0001, P = 0.0006, P = 0.04 and P = 0.0002, respectively). F{sub T} was the most relevant factor for discriminating malignant from benign tumours (AUROC = 0.86). Primary ovarian invasive tumours displayed higher F{sub T} and shorter Dt than borderline tumours. Malignant adnexal tumours with associated peritoneal carcinomatosis at surgery displayed a shorter Dt than those without peritoneal carcinomatosis at surgery (P = 0.01). Quantitative DCE-MRI is a feasible and accurate technique to differentiate malignant from benign adnexal tumours and could potentially help oncologists with management decisions. (orig.)

  10. PRELIMINARY STUDY OF FEASIBILITY OF WHOLE BODY DIFFUSION WEIGHTED IMAGING IN DIAGNOSIS OF METASTASIS OF TUMOR

    Institute of Scientific and Technical Information of China (English)

    Tian-he Yang; Jian-zhong Lin; Xin Wang; Jian-hua Lu; Zhong Chen

    2008-01-01

    Objective To evaluate the feasibility of whole body diffusion weighted imaging (DWI) in the diagnosis of metastatic tumor.Methods Fifty-six patients (40 males and 16 females, age ranging from 29 to 84 years with a mean age of 57 years) with a variety of primary tumors were investigated by whole body DWI combined with computed tomography (CT) and/or conventional magnetic resonance imaging (MRI) scans. Twelve patients underwent positron emission tomography. The final diagnosis was made on the basis of CT or high resolution CT result for lung lesion and MRI or CT result for skull, abdomen and other parts. All tumors were classified into four groups by their diameter: below 1.0 cm, 1.0-1.9 cm, 2.0-2.9 cm, and above 3.0 cm. The sensitivity and specificity of whole body DWI in the detection of metastatic tumor were analyzed.Results The sensitivities of whole body DWI for screening metastasis oftlie four groups were 38%, 75%, 97%, and 100%, respectively. Whole body DWI showed the highest sensitivity and specificity for detecting metastasis of the skeletal system. It was difficult to find metastatic tumor whose diameter was below 1.0 cm, or lymph nodes located in the pelvis with diameter below 2.0 cm. Conclusions Whole body DWI is a promising method in the diagnosis ofmetastastic tumors. With the perfection of scanning parameter, whole body DWI should be a new effective whole body technique for tumor detection.

  11. Magnetization transfer imaging reveals geniculocalcarine and striate area degeneration in primary glaucoma: a preliminary study

    Directory of Open Access Journals (Sweden)

    Yan Zhang

    2016-09-01

    Full Text Available Background Glaucoma is a neurodegenerative disease that affects both the retina and central visual pathway. Magnetization transfer imaging (MTI is a sensitive magnetic resonance imaging (MRI technique that can detect degenerative changes in the brain. Purpose To investigate the geniculocalcarine (GCT and striate areas in primary glaucoma patients using region of interest (ROI analysis of magnetization transfer ratio (MTR. Material and Methods Twenty patients with primary glaucoma in both eyes were compared with 31 healthy control patients. All of the participants were examined on a 3.0 T scanner using a three-dimensional T1-weighted spoiled gradient recalled acquisition (SPGR with and without a MT saturation pulse. A two-sample t-test was used to evaluate the MTR difference between the groups. P < 0.05 was used to determine statistical significance. Results The MTR of the glaucoma group was lower than the healthy controls in both the bilateral GCT (t = 3.781, P = 0.001 and striate areas (t = 4.177, P = 0.000. Conclusion The MTR reductions in the bilateral GCT and striate areas suggest that there is GCT demyelination and striate area degeneration in primary glaucoma. These neurodegenerative effects may be induced as a direct effect of retrograde axonal degeneration along with the indirect effect of anterograde trans-synaptic degeneration.

  12. Real-Time Monitoring of Occupants’ Thermal Comfort through Infrared Imaging: A Preliminary Study

    Directory of Open Access Journals (Sweden)

    Boris Pavlin

    2017-02-01

    Full Text Available Thermally comfortable indoor environments are of great importance, as modern lifestyles often require people to spend more than 20 h per day indoors. Since most of the thermal comfort models use a variety of different environmental and personal factors that need to be measured or estimated, real-time and continuous assessment of thermal comfort is often not practically feasible. This work presents a cheap and non-invasive approach based on infrared imaging for monitoring the occupants’ thermal sensation and comfort in real time. Thanks to a mechatronic device developed by the authors, the imaging is performed on the forehead skin, selected because it is always exposed to the environment and, thus, facilitating the monitoring activity in a non-invasive manner. Tests have been performed in controlled conditions on ten subjects to assess the hypothesis that the forehead temperature is correlated with subjects’ thermal sensation. This allows the exploitation of this quantity as a base for a simple monitoring of thermal comfort, which could later be tuned with an extensive experimental campaign.

  13. Preparation and preliminary biological evaluation of 99Tcm-TADP as bone imaging agent

    Institute of Scientific and Technical Information of China (English)

    YAN Xiaohong; LUO Shineng; NIU Guosai; YE Wanzhong; YANG Min; WANG Hongyong; XIA Yongmei

    2008-01-01

    TADP, 2-(1H-1,2,4-triazol-1-yl)-1-hydroxyethane-1,1-diphosphonic acid, was synthesized by three step reactions from the raw material 1H-1,2,4-triazole. 99Tcm-TADP was prepared with 5 mg TADP at Ph 7.0 by joining 99TcmO4 with SnCl2·2H2O in aqueous solution for 10 min at room temperature. Both labeling yield and radiochemical purity of 99Tcm-TADP were more than 95%. The biodistribution in rats and bone scan in rabbits were also studied. The uptake of organ was expressed as %ID/g. The results showed that the bone uptake is up to 17.17%ID/g which is the maximum of bone uptake at 30 min after injection of 99Tcm-TADP in rats, bone-to-muscle and bone-to-blood uptake ratios were 61.32 and 13.21, respectively. The clear bone image of rabbit was obtained at 120 min after injection of 99Tcm-TADP and clearance in soft tissue was visible. The preparation of 99Tcm-TADP was convenient and 99Tcm-TADP exhibited high uptake in bone, and it would be a potential new bone imaging agent.

  14. Preliminary gully assessment using photo-reconstruction from own-manufactured UAV images

    Science.gov (United States)

    Ruano-Castro, Vicente; Castillo, Carlos; Gomez, Jose A.; Perez, Rafael

    2014-05-01

    Unmanned Aerial Vehicles (UAV) are becoming increasingly useful in several professional and research fields, among other, in geomorphology applications. UAV helicopters (with one or more rotors) present some advantages compared to fixed wing drones such as the possibility of stationary fly. On the other hand, 3D-photoreconstruction has been successfully applied for gully assessment at the reach scale. The combination of both approaches can result in a substantial reduction of time requirements at the gully network scale. The purpose of this communication is to describe the construction of an UAV with carbor-fiber frame and its fitting for capturing air images. Routes controlled by GPS were programmed in advance using Google Earth. Although an improved design with 8 rotors is in progress, currently the design is equipped with 4 rotors. This new design will allow the use of heavier and more precise cameras. In addition, the isolation of the inner electronic equipment will increase the possibility of use in bad weather. The images obtained by the UAV were processed using 3D-photoreconstruction to derive a digital elevation model of a several-hundred meters gully. References Castillo, C., R. Perez, M.R. James, J.N. Quinton, E.V. Taguas, J.A. Gómez. 2012. Comparing the Accuracy of Several Field Methods for Measuring Gully Erosion. Soil Science Society of America Journal 76: 1319-1332.

  15. Assessment of trabecular bone changes around endosseous implants using image analysis techniques: A preliminary study

    Energy Technology Data Exchange (ETDEWEB)

    Zuki, Mervet El [Dept. of Oral Medicine and Radiology, Benghazi University College of Dentistry, Benghazi (Libya); Omami, Galal [Oral Diagnosis and Polyclinics, Faculty of Dentistry, The University of Hong Kong (Hong Kong); Horner, Keith [Dept. of Oral Radiology, University Dental Hospital of Manchester, Manchester (United Kingdom)

    2014-06-15

    The objective of this study was to assess the trabecular bone changes that occurred around functional endosseous dental implants by means of radiographic image analysis techniques. Immediate preoperative and postoperative periapical radiographs of de-identified implant patients at the University Dental Hospital of Manchester were retrieved, screened for specific inclusion criteria, digitized, and quantified for structural elements of the trabecular bone around the endosseous implants, by using image analysis techniques. Data were analyzed using SPSS version 11.5. P values of less than 0.05 were considered statistically significant. A total of 12 implants from 11 patients were selected for the study, and 26 regions of interest were obtained. There was a significant increase in the bone area in terms of the mean distance between nodes (p=0.006) and a significant decrease in the marrow area in terms of the bone area (p=0.006) and the length of marrow spaces (p=0.032). It appeared that the bone around the implant underwent remodeling that resulted in a net increase in bone after implant placement.

  16. Synthesis and preliminary evaluation of 2-arylhydroxyquinoline derivatives for tau imaging.

    Science.gov (United States)

    Tago, Tetsuro; Furumoto, Shozo; Okamura, Nobuyuki; Harada, Ryuichi; Ishikawa, Yoichi; Arai, Hiroyuki; Yanai, Kazuhiko; Iwata, Ren; Kudo, Yukitsuka

    2014-01-01

    Alzheimer's disease (AD) is the most common cause of dementia. Senile plaques, consisting of β-amyloid, and neurofibrillary tangles (NFTs), composed of tau protein, are representative pathological hallmarks of AD. It is believed that the accumulation of NFTs precedes the onset of clinical symptoms of AD and correlates with the progression of memory dysfunction. Thus, the use of noninvasive detection techniques including radiolabeled probes and positron emission tomography (PET) will facilitate early diagnosis or staging of AD. In this study, we synthesized and evaluated novel hydroxylated 2-arylquinoline derivatives as tau imaging PET probes. The binding affinities of compounds for tau were evaluated by fluorescent staining of the AD hippocampal section and a competitive binding assay using [(18) F]THK-523. THK-951 showed high binding affinity for tau pathology in an AD brain section and K18Δ280K fibrils (Ki  = 20.7 nM); thus, we radiosynthesized a (11) C-labeled THK-951 and further studied its potential as a tau PET probe. The [(11) C]THK-951 demonstrated excellent kinetics in a normal mouse brain (3.23% ID/g at 2 min postinjection and 0.15% ID/g at 30 min postinjection) and showed the labeling of NFTs in an AD brain section by autoradiography assay. These findings indicate the availability of [(11) C]THK-951 for in vivo PET imaging of tau pathology in AD. Copyright © 2013 John Wiley & Sons, Ltd.

  17. Magnetic resonance imaging of the fetus in congenital intrathoracic disorders: preliminary observations

    Energy Technology Data Exchange (ETDEWEB)

    Liu Xiang; Ashtari, M.; Leonidas, J.C. [Dept. of Radiology, Schneider Children' s Hospital, Long Island Jewish Medical Center, NY (United States); Chan Ying [Fetal-Maternal Medicine, Schneider Children' s Hospital, Long Island Jewish Medical Center, and the Albert Einstein College of Medicine, NY (United States)

    2001-06-01

    Background and objective. Advances in magnetic resonance imaging (MRI) provide high-quality images of the intrathoracic organs. We studied the ability of MRI to define spatial relationships of the fetal lungs and measured lung volume in two cases of congenital diaphragmatic hernia (CDH), one of severe oligohydramnios secondary to bilateral cystic renal dysplasia and one case of prenatal chylothorax. Patients and methods. We performed pelvic MRI using single-shot fast spin echo (SSFSE) pulse sequence in four pregnant women referred because of abnormal prenatal ultrasound (US) findings associated with pulmonary hypoplasia. Results. The exact anatomic position of the contents of the hernia in CDH, including the position of the liver, was better defined with MRI. Pleural effusions were identified as well as the renal abnormality in the case of oligohydramnios. Lung volume was measured and the degree of pulmonary hypoplasia was quantified in every case. Lung-to-thorax ratio was calculated in the case of fetal chylothorax. Conclusion. Ongoing work suggests that MRI can provide additional detailed quantitative information in prenatal disorders associated with fetal lung compression and resulting hypoplasia. Correlation of fetal lung volume with postnatal management and outcome may affect prognosis in these cases. (orig.)

  18. Assessment of liver steatosis in chicken by using acoustic radiation force impulse imaging: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Guzman Aroca, Florentina; Serrano, Laura; Berna-Serna, Juan D.; Reus, Manuel [Virgen de la Arrixaca University Hospital, Department of Radiology, El Palmar, Murcia (Spain); Ayala, Ignacio [University of Murcia, Department of Animal Medicine and Surgery, Murcia (Spain); Castell, Maria T. [University of Murcia, Department of Cell Biology, Murcia (Spain); Garcia-Perez, Bartolome [Virgen de la Arrixaca University Hospital, Internal Medicine Service, El Palmar, Murcia (Spain)

    2010-10-15

    To evaluate acoustic radiation force impulse (ARFI) imaging as a non-invasive tool for quantification of the grades of liver steatosis in chickens. We used two different diets: a standard diet (SD group) and a hyperlipidaemic diet (HD group). The ARFI technique was performed in all the animals in the right hepatic lobe and shear wave velocity (SWV) was measured and expressed in metres per second (m/s). Plasma lipid levels were analysed. Steatosis was quantified by using semiquantitative analysis. Statistical analysis was used and Pearson's correlation coefficient was calculated. Mean SWV was 0.94 {+-} 0.16 m/s (range 0.8-1.3 m/s) in the SD group and 1.91 {+-} 0.25 m/s (range 1.3-2.2 m/s) in the HD group (p < 0.001). The lowest SWVs ({<=}1.3 m/s) corresponded to the chickens in the SD group, with 100% of the animals returning a score of 0, whereas the range of SWV in the HD group chickens was between 1.6 and 2.2 m/s. A substantial correlation was observed between SWVs with histological semiquantitative analysis of steatosis (r = 0.85, p < 0.001). ARFI imaging is a non-invasive diagnostic tool that allows discrimination between the grades of liver steatosis in chickens. (orig.)

  19. Diffusion tensor imaging applications in multiple sclerosis patients using 3T magnetic resonance: a preliminary study

    Energy Technology Data Exchange (ETDEWEB)

    Testaverde, Lorenzo; Caporali, Laura [University ' ' Sapienza' ' of Rome, Department of Radiological Sciences, Rome (Italy); Venditti, Eugenio; Grillea, Giovanni [U.O.C. Neuroradiologia, I.R.C.C.S. ' ' Neuromed' ' , Pozzilli (Italy); Colonnese, Claudio [University ' ' Sapienza' ' of Rome, Department of Radiological Sciences, Rome (Italy); U.O.C. Neuroradiologia, I.R.C.C.S. ' ' Neuromed' ' , Pozzilli (Italy)

    2012-05-15

    This study evaluated patients with multiple sclerosis using diffusion tensor imaging (DTI) to obtain fractional anisotropy (FA) and mean diffusivity (MD) values. We investigated the possible statistically significant variation of MD and FA in different MS patients, compared simultaneously, putting in comparison their normal appearing white matter (NAWM) and white matter affected by disease (plaques), both during activity and in remission, with normal white matter (NWM) of control subjects. Statistical analysis using Levene's test for comparison of variances revealed significant (P < 0.05) differences between FA values of the NWM of the controls and those of NAWM and active or inactive lesions, of the patients in the study. However, the differences between MD values of the NWM of the controls and those of NAWM and active or inactive lesions of the patients in the study were judged not significant (P > 0.05). Imaging of MS using MRI techniques is constantly searching for reproducible quantitative parameter. This study shows how these parameters can be identified in the MD and FA values, and thus suggests the implementation of MRI routine protocols for diagnosing MS with the DTI analysis, since it can provide valuable information otherwise unobtainable. (orig.)

  20. Preliminary Research on Dual-Energy X-Ray Phase-Contrast Imaging

    CERN Document Server

    Han, Huajie; Gao, Kun; Wang, Zhili; Zhang, Can; Yang, Meng; Zhang, Kai; Zhu, Peiping

    2015-01-01

    Dual-energy X-ray absorptiometry (DEXA) has been widely applied to measure bone mineral density (BMD) and soft-tissue composition of human body. However, the use of DEXA is greatly limited for low-Z materials such as soft tissues due to their weak absorption. While X-ray phase-contrast imaging (XPCI) shows significantly improved contrast in comparison with the conventional standard absorption-based X-ray imaging for soft tissues. In this paper, we propose a novel X-ray phase-contrast method to measure the area density of low-Z materials, including a single-energy method and a dual-energy method. The single-energy method is for the area density calculation of one low-Z material, while the dual-energy method is aiming to calculate the area densities of two low-Z materials simultaneously. Comparing the experimental and simulation results with the theoretic ones, the new method proves to have the potential to replace DEXA in area density measurement. The new method sets the prerequisites for future precise and lo...

  1. Beneficial uses of geothermal energy description and preliminary results for phase 1 of the Raft River irrigation experiment

    Energy Technology Data Exchange (ETDEWEB)

    Schmitt, R.C.; Spencer, S.G.

    1977-01-01

    The first phase of an experiment using geothermal water for irrigation is described and preliminary results are discussed. The water was from a moderate temperature well, having salinity of about 2000 ppM, and is considered characteristic of the types of geothermal fluids that will be obtained from the young volcanic/young sediment formations of the northern intermountain west. The activity was completed at a location adjacent to ERDA's Raft River Geothermal Project in southern Idaho. About 12.5 acres, of which part had no previous cultivation, were subdivided by crops and irrigation practices for investigation with the geothermal water and a control comparison water from the relatively pure Raft River. Flood and sprinkler application techniques were used and wheat, barley, oats, grasses, alfalfa, potatoes, and garden vegetables were successfully grown. An accompanying experiment evaluated the behavior of an established alfalfa crop located nearby, when most of the irrigation water was geothermal. The experiment addressed heavy metal uptake in plants, plant fluoride retention and damage, plant tolerances to salts, soil alterations and other behavior as a result of the geothermal fluids, all of which were largely believed to eliminate geothermal water from contention for crop growing utilization. Not all analyses and results are complete in this reporting, but first results indicate no apparent difference between the geothermal watered crops and those obtained using the fresh water control. Extensive chemical analyses, neutron activation analyses, and other evaluations of crop samples are discussed, and some of the findings are presented. Although evaluation of crop yields was not an objective, extrapolations from samples indicate that yield results were comparable to those commonly found in the area, and the yield varied little between water sources. (JGB)

  2. Gamma Knife Radiosurgery in Sphenopetroclival Meningiomas: Preliminary Experience at the Iran Gamma Knife Center.

    Science.gov (United States)

    Azar, Maziar; Kazemi, Farid; Chanideh, Iran; Amirjamshidi, Abbas; Amini, Elahe; Ghanavati, Pedram

    2016-09-01

    The aims of this study were to characterize the epidemiologic, histologic, and radiologic aspects of sphenopetroclival meningiomas (SpPCMs) and to evaluate the outcome of Gamma Knife radiosurgery (GKRS) either as an adjunct to microsurgery or as a primary SpPCM treatment modality. In this retrospective study, medical records of patients with SpPCM who underwent GKRS at the Iran Gamma Knife Center between April 2003 and March 2012 were analyzed. We assessed 122 patients with SpPCMs, including 101 women and 21 men, aged 24-94 years. The mean tumor volume was 12.24 ± 9.30 mL. Patients received 22.32 ± 3.29 Gy and 13.18 ± 1.02 Gy maximal and average marginal dose of GKRS, respectively. The most common complaint was visual impairment, followed by facial sensory impairment and headache. The most frequently involved cranial nerves were III, IV, and VI in 72.1% of patients, followed by II in 52.9%, and V in 35.5%. After radiosurgery, headaches improved in 90.0%, diplopia in 75.0%, and ptosis in 63.0% of patients. On magnetic resonance imaging, tumor size was reduced, unchanged, or increased in 77, 44, and 1 patient, respectively. Progression-free survival at the 5-year follow-up was 56.6%. Younger age (hazard ratio = 0.972, P = 0.011) and lower tumor volume (hazard ratio = 0.959, P = 0.009) were the main prognostic factors for progression-free survival. GKRS can be an effective alternative treatment for controlling the progression of SpPCM tumors, producing appropriate clinical outcomes and few complications. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Experience With Intravascular Ultrasound Imaging Of Human Atherosclerotic Arteries

    Science.gov (United States)

    Mallery, John A.; Gessert, James M.; Maciel, Mario; Tobis, John M.; Griffith, James M.; Berns, Michael W.; Henry, Walter L.

    1989-08-01

    Normal human arteries have a well-defined structure on intravascular images. The intima appears very thin and is most likely represented by a bright reflection arising from the internal elastic lamina. The smooth muscle tunica media is echo-lucent on the ultrasound image and appears as a dark band separating the intima from the adventitia. The adventitia is a brightly reflective layer of variable thickness. The thickness of the intima, and therefore of the atherosclerotic plaque can be accurately measured from the ultrasound images and correlates well with histology. Calcification within the wall of arteries is seen as bright echo reflection with shadowing of the peripheral wall. Fibrotic regions are highly reflective but do not shadow. Necrotic liquid regions within advanced atherosclerotic plaques are seen on ultrasound images as large lucent zones surrounded by echogenic tissue. Imaging can be performed before and after interventional procedures, such as laser angioplasty, balloon angioplasty and atherectomy. Intravascular ultrasound appears to provide an imaging modality for identifying the histologic characteristics of diseased arteries and for quantifying plaque thickness. It might be possible to perform such quantification to evaluate the results of interventional procedures.

  4. Development of a lower extremity wearable exoskeleton with double compact elastic module: preliminary experiments

    Directory of Open Access Journals (Sweden)

    Y. Long

    2017-08-01

    Full Text Available In this paper, a double compact elastic module is designed and implemented in the lower extremity exoskeleton. The double compact elastic module is composed of two parts, i.e., physical human robot interaction (pHRI measurement and the elastic actuation system (EAS, which are called proximal elastic module (PEM and distal elastic module (DEM respectively. The PEM is used as the pHRI information collection device while the DEM is used as the compliance device. A novel compact parallelogram-like structure based torsional spring is designed and developed. An iterative finite element analysis (FEA based optimization process was conducted to find the optimal parameters in the search space. In the PEM, the designed torsional spring has an outer circle with a diameter of 60 mm and an inner hole with a diameter of 12 mm, while in the DEM, the torsional spring has the outer circle with a diameter of 80 mm and the inner circle with a diameter of 16 mm. The torsional spring in the PEM has a thickness of 5 mm and a weight of 60 g, while that in the DEM has a thickness of 10 mm and a weight of 80 g. The double compact elastic module prototype is embedded in the mechanical joint directly. Calibration experiments were conducted on those two elastic modules to obtain the linear torque versus angle characteristic. The calibration experimental results show that this torsional spring in the PEM has a stiffness of 60.2 Nm rad−1, which is capable of withstanding a maximum torque of 4 Nm, while that in the DEM has a stiffness of 80.2 Nm rad−1, which is capable of withstanding a maximum torque of 30 Nm. The experimental results and the simulation data show that the maximum resultant errors are 6 % for the PEM and 4 % for the DEM respectively. In this paper, an assumed regression algorithm is used to learn the human motion intent (HMI based on the pHRI collection. The HMI is defined as the angular position of the human limb joint. A

  5. Wearable ultrasonic guiding device with white cane for the visually impaired: A preliminary verisimilitude experiment.

    Science.gov (United States)

    Cheng, Po-Hsun

    2016-01-01

    Several assistive technologies are available to help visually impaired individuals avoid obstructions while walking. Unfortunately, white canes and medical walkers are unable to detect obstacles on the road or react to encumbrances located above the waist. In this study, I adopted the cyber-physical system approach in the development of a cap-connected device to compensate for gaps in detection associated with conventional aids for the visually impaired. I developed a verisimilar, experimental route involving the participation of seven individuals with visual impairment, including straight sections, left turns, right turns, curves, and suspended objects. My aim was to facilitate the collection of information required for the practical use of the device. My findings demonstrate the feasibility of the proposed guiding device in alerting walkers to the presence of some kinds of obstacles from the small number of subjects. That is, it shows promise for future work and research with the proposed device. My findings provide a valuable reference for the further improvement of these devices as well as the establishment of experiments involving the visually impaired.

  6. Flexible robotic retrograde renoscopy: description of novel robotic device and preliminary laboratory experience.

    Science.gov (United States)

    Desai, Mihir M; Aron, Monish; Gill, Inderbir S; Pascal-Haber, Georges; Ukimura, Osamu; Kaouk, Jihad H; Stahler, Gregory; Barbagli, Federico; Carlson, Christopher; Moll, Fredric

    2008-07-01

    To describe a novel flexible robotic system for performing retrograde intrarenal surgery. Remote robotic flexible ureterorenoscopy was performed bilaterally in 5 acute swine (10 kidneys). A novel 14F robotic catheter system, which manipulated a passive optical fiberscope mounted on a remote catheter manipulator was used. The technical feasibility, efficiency, and reproducibility of accessing all calices were assessed. Additionally, laser lithotripsy of calculi and laser ablation of renal papillae were performed. The robotic catheter system could be introduced de novo in eight ureters; two ureters required balloon dilation. The ureteroscope could be successfully manipulated remotely into 83 (98%) of the 85 calices. The time required to inspect all calices within a given kidney decreased with experience from 15 minutes in the first kidney to 49 seconds in the last (mean 4.6 minutes). On a visual analog scale (1, worst to 10, best), the reproducibility of caliceal access was rated at 8, and instrument tip stability was rated at 10. A renal pelvic perforation constituted the solitary complication. Histologic examination of the ureter showed changes consistent with acute dilation without areas of necrosis. A novel robotic catheter system is described for performing retrograde ureterorenoscopy. The potential advantages compared with conventional manual flexible ureterorenoscopy include an increased range of motion, instrument stability, and improved ergonomics. Ongoing refinement is likely to expand the role of this technology in retrograde intrarenal surgery in the near future.

  7. Preliminary results from recent experiments and future roadmap to Shock Ignition of Fusion Targets

    Science.gov (United States)

    Batani, D.; Malka, G.; Schurtz, G.; Ribeyre, X.; Lebel, E.; Giuffrida, L.; Tikhonchuk, V.; Volpe, L.; Patria, A.; Koester, P.; Labate, L.; Gizzi, L. A.; Antonelli, L.; Richetta, M.; Nejdl, J.; Sawicka, M.; Margarone, D.; Krus, M.; Krousky, E.; Skala, J.; Dudzak, R.; Velyhan, A.; Ullshmied, J.; Renner, O.; Smid, M.; Klimo, O.; Atzeni, S.; Marocchino, A.; Schiavi, A.; Spindloe, C.; O'Dell, T.; Vinci, T.; Wolowski, J.; Badziak, J.; Pysarcizck, T.; Rosinski, M.; Kalinowska, Z.; Chodukowski, T.

    2012-11-01

    Shock ignition (SI) is a new approach to Inertial Confinement Fusion (ICF) based on decoupling the compression and ignition phase. The last one relies on launching a strong shock through a high intensity laser spike (<= 1016 W/cm2) at the end of compression. In this paper, first we described an experiment performed using the PALS iodine laser to study laser-target coupling and laser-plasma interaction in an intensity regime relevant for SI. A first beam with wavelength λ = 1.33 μm and low intensity was used to create an extended preformed plasma, and a second one with λ = 0.44 μm to create a strong shock. Several diagnostics characterized the preformed plasma and the interaction of the main pulse. Pressure up to 90 Mbar was inferred. In the last paper of the paper, we discuss the relevant steps, which can be followed in order to approach the demonstration of SI on laser facilities like LMJ.

  8. Investigation of Freeze-Linings in Copper-Containing Slag Systems: Part I. Preliminary Experiments

    Science.gov (United States)

    Fallah-Mehrjardi, Ata; Hayes, Peter C.; Jak, Evgueni

    2013-06-01

    Slag freeze-linings are increasingly used in industrial pyrometallurgical processes to insure that furnace integrity is maintained in aggressive high-temperature environments. Most previous studies of freeze-linings have analyzed the formation of slag deposits based solely on heat-transfer models. The focus of the present research is to determine the impact of slag chemistry and local process conditions on the microstructures, thickness, stability, and heat-transfer characteristics of the frozen deposit at steady-state conditions. The formation of the freeze-linings is studied under controlled laboratory conditions using an air-cooled "cold-finger" technique for Cu-Fe-Si-Al-O slag at equilibrium with metallic copper relevant to the industrial copper smelting processes. The phase assemblages and microstructures of the deposits formed in the cold-finger experiments differ significantly from those expected from phase equilibrium considerations. The freeze-lining deposits have been found, in general, to consist of several layers. Starting from the cold finger, these layers consist of glass; glass with microcrystalline precipitates; closed crystalline layer; and open crystalline layer. Even at steady-state conditions, there was no primary phase sealing layer of delafossite [Cu2O · (Al, Fe)2O3] present at the deposit/liquid interface—these observations differ markedly from those expected from phase equilibrium considerations. The findings have significant practical implications, and potential for the improved design and operation of industrial metallurgical furnaces.

  9. Preliminary experience with extraperitoneal endoscopic radical prostatectomy through duplication of the open technique

    Directory of Open Access Journals (Sweden)

    M. Tobias-Machado

    2005-06-01

    Full Text Available OBJECTIVE: To describe surgical and functional results with extraperitoneal laparoscopic radical prostatectomy with duplication of the open technique, from the experience obtained in the treatment of 28 initial cases. MATERIALS AND METHODS: In a 36-month period, we prospectively analyzed 28 patients diagnosed with localized prostate cancer undergoing extraperitoneal laparoscopic radical prostatectomy. RESULTS: Mean surgical time was 280 min, with mean blood loss of 320 mL. As intraoperative complications, there were 2 rectal lesions repaired with laparoscopic suture in 2 planes. There was no conversion to open surgery. Median hospital stay was 3 days, with return to oral diet in the first post-operative day in patients. As post-operative complications, there were 3 cases of extraperitoneal urinary fistula. Two of these cases were resolved by maintaining a Foley catheter for 21 days, and the other one by late endoscopic reintervention for repositioning the catheter. Five out of 18 previously potent patients evolved with erectile dysfunction. The diagnosis of prostate cancer was confirmed in all patients, with focal positive margin occurring in 3 cases. During a mean follow-up of 18 months, 2 patients presented increased PSA, with no clinical evidence of disease. CONCLUSION: Laparoscopic radical prostatectomy is a laborious and difficult procedure, with a long learning curve. Extraperitoneal access is feasible, and it is possible to practically duplicate the principles of open surgery. The present technique can possibly offer advantages in terms of decreased blood loss, preservation of erectile function and prevention of positive margins.

  10. Preliminary culture and life-cycle experiments with the benthic amphipod Ampelisca abdita

    Energy Technology Data Exchange (ETDEWEB)

    Redmond, M.S.; Jones, J.K.P. (AScI Corp., Newport, OR (United States)); Scott, K.J. (Science Applications International Corp., Narragansett, RI (United States)); Swartz, R.C. (Environmental Protection Agency, Newport, OR (United States))

    1994-08-01

    The tube-dwelling amphipod Ampelisca abdita Mills 1964 has been used extensively in acute sediment toxicity tests and has been shown to be amenable to chronic testing. Ampelisca abdita was held in the lab through several generations when fed algal food in daily static renewals, although culturing success was not consistent. Algal food consisted of one or more of the following: the flagellate Pseudoisochrysis paradoxa Sutton, and the diatoms Phaeodactylum tricornutum Bohlin and Chaetoceros calcitrans (Paulsen) Tokano. Sensitivity of cultured animals to cadmium chloride in 96-h seawater-only tests was comparable to that of field-collected animals. A life-cycle test initiated with juveniles 8 to 10 d old resulted in production of young or fertilized broods in only two of the 12 sample containers in which young were expected. Amphipods were sexually mature at approximately 20 d of age at 25 C, and young were first produced at 34 to 36 d. Short-term tests were used to quantify growth of this species in 10 to 14 d. Results from a variety of experiments indicated that there are still one or more unresolved problems with the culture and chronic testing of Ampelisca abdita. Factors such as nutrition, flow rate, light, and temperature need to be examined further.

  11. Video-assisted anal fistula treatment: technical considerations and preliminary results of the first Brazilian experience.

    Science.gov (United States)

    Mendes, Carlos Ramon Silveira; Ferreira, Luciano Santana de Miranda; Sapucaia, Ricardo Aguiar; Lima, Meyline Andrade; Araujo, Sergio Eduardo Alonso

    2014-01-01

    Anorectal fistula represents an epithelized communication path of infectious origin between the rectum or anal canal and the perianal region. The association of endoscopic surgery with the minimally invasive approach led to the development of the video-assisted anal fistula treatment. To describe the technique and initial experience with the technique video-assisted for anal fistula treatment. A Karl Storz video equipment was used. Main steps included the visualization of the fistula tract using the fistuloscope, the correct localization of the internal fistula opening under direct vision, endoscopic treatment of the fistula and closure of the internal opening which can be accomplished through firing a stapler, cutaneous-mucosal flap, or direct closure using suture. The mean distance between the anal verge and the external anal orifice was 5.5 cm. Mean operative time was 31.75 min. In all cases, the internal fistula opening could be identified after complete fistuloscopy. In all cases, internal fistula opening was closed using full-thickness suture. There were no intraoperative or postoperative complications. After a 5-month follow-up, recurrence was observed in one (12.5%) patient. Video-assisted anal fistula treatment is feasible, reproducible, and safe. It enables direct visualization of the fistula tract, internal opening and secondary paths.

  12. Body image and restrained eating in blind and sighted women: A preliminary study.

    Science.gov (United States)

    Ashikali, Eleni-Marina; Dittmar, Helga

    2010-03-01

    Sociocultural theory attributes the high levels of body image concerns and disordered eating in Western women to the promotion of an unrealistically thin body ideal. This study investigated body dissatisfaction, restrained eating, and attitudes toward appearance in visually impaired and sighted women. There were 21 congenitally blind, 11 blinded later in life, and 60 sighted. Blind women were more satisfied with their body and dieted less than sighted women. Appearance attitudes, particularly thin-ideal internalization, accounted for differences in body dissatisfaction and dieting among the three groups of women. Possible explanations for our findings are considered, including the importance of visual exposure to the media's thin ideal, as well as the usefulness of future research on blind women. Copyright 2010 Elsevier Ltd. All rights reserved.

  13. PRELIMINARY APPLICATION OF COLOR DOPPLER FLOW IMAGING IN THE LOCALIZATION OF PARATHYROID ADENOMAS

    Institute of Scientific and Technical Information of China (English)

    张缙熙; 李建初

    1994-01-01

    From December 1991 to April 1993,we performed color Doppler flow imaging(CDFI) in 11 patients with parathyroid adenoma,and all cases were confirmed by toperation and pathology.In all the parathyroid adenomas,vessels were clearly revealed at the periphery of the upper pole and /or anterior periphery,where arterial signals were elicited.These arteries had branches into the adenomas and originated from inferior thyroid arteries on the same side in most cases.The internal flow signals were increased markedly as compared to normal thyroid,and high-velocity arterial signals were detected.Because of the thyroid's rich blood supply and landmark peripheral vessels.CDFI can distinguish parathyroid foci from thyroid nodules,lymph nodes,and normal tissues and provide a sound basis for the diagnosis of small parathyroid foci.

  14. Primary progressive aphasia patients evaluated using diffusion tensor imaging and voxel based volumetry-preliminary results

    Directory of Open Access Journals (Sweden)

    Fábio Pascotto de Oliveira

    2011-06-01

    Full Text Available There are individuals who have a progressive language deficit without presenting cognitive deficits in other areas. One of the diseases related to this presentation is primary progressive aphasia (PPA. OBJECTIVE: Identify by means of diffusion tensor imaging (DTI and measurements of cortical volume, brain areas that lead to dysphasia when presenting signs of impaired connectivity or reduced volume. METHOD: Four patients with PPA were evaluated using DTI, and measurements of cortical volumes in temporal areas. These patients were compared with two normal volunteers. RESULTS: There is a trend to a difference in the number and volume of related fibers between control group and patients with PPA. Comparing cortical volumes in temporal areas between groups yielded a trend to a smaller volume in PPA patients. CONCLUSION: Patients with PPA have a trend to impairment in cortical and subcortical levels regarding relevant areas.

  15. PRELIMINARY APPLICATION OF WHOLE BODY DIFFUSION WEIGHTED IMAGING IN SCREENING METASTASIS

    Institute of Scientific and Technical Information of China (English)

    Yong-jing Guan; Hua-wei Ling; Ke-min Chen

    2008-01-01

    Objective To investigate the feasibility of whole body diffusion weighted imaging (WB-DWI) in screening metastasis.Methods WB-DWI was performed in 24 patients diagnosed with various types of primary tumors. The three-dimensional maximum intensity projection reconstruction and black-and-white flip technique were used to observe metastatic lesions, and the results were compared with those of bone scintigraphy. Results By WB-DWI scanning sequence at b = 800 s/mm2, all the bone lesions found by bone scintigraphy in the cohort were well identified, and other lesions of soft tissue and organs were also well demonstrated. Its screening capability was equivalent with bone scintigraphy in screening metastases in bones (P = 0.062). Conclusion WB-DWI was practicable with the parameter settings attempted in metastases screening.

  16. Design and preliminary performance evaluation of airborne hyper-spectral imaging spectograph Air-OPUS

    Science.gov (United States)

    Okumura, Shin-ichiro; Suzuki, Makoto; Yoshida, Shigeomi; Sano, Takuki; Watanabe, Masaharu; Ogawa, Toshihiro

    2003-06-01

    Air-OPUS is a hyper spectral imaging spectrograph, with 0.34 nm spectral step, 190-455 nm spectral coverage, and 330 spatial channels covering 15 degrees field of view (FOV). It is designed as an airborne instrument for the demonstration of spaceborne-OPUS. After two-demonstration campaign using the Gulfstream-II aircraft, the performances of AIR-OPUS, such as spectral resolution, signal-to-noise ration (SNR) have been evaluated. It is concluded that the performances have agreed with designed value. This paper describes design, the performance, and the first results of Air-OPUS. Concept of next generation Air-OPUS, with wider FOV and visible/near-IR spectral coverage, will be also briefly presented.

  17. Adaptive clutter rejection for 3D color Doppler imaging: preliminary clinical study.

    Science.gov (United States)

    Yoo, Yang Mo; Sikdar, Siddhartha; Karadayi, Kerem; Kolokythas, Orpheus; Kim, Yongmin

    2008-08-01

    In three-dimensional (3D) ultrasound color Doppler imaging (CDI), effective rejection of flash artifacts caused by tissue motion (clutter) is important for improving sensitivity in visualizing blood flow in vessels. Since clutter characteristics can vary significantly during volume acquisition, a clutter rejection technique that can adapt to the underlying clutter conditions is desirable for 3D CDI. We have previously developed an adaptive clutter rejection (ACR) method, in which an optimum filter is dynamically selected from a set of predesigned clutter filters based on the measured clutter characteristics. In this article, we evaluated the ACR method with 3D in vivo data acquired from 37 kidney transplant patients clinically indicated for a duplex ultrasound examination. We compared ACR against a conventional clutter rejection method, down-mixing (DM), using a commonly-used flow signal-to-clutter ratio (SCR) and a new metric called fractional residual clutter area (FRCA). The ACR method was more effective in removing the flash artifacts while providing higher sensitivity in detecting blood flow in the arcuate arteries and veins in the parenchyma of transplanted kidneys. ACR provided 3.4 dB improvement in SCR over the DM method (11.4 +/- 1.6 dB versus 8.0 +/- 2.0 dB, p < 0.001) and had lower average FRCA values compared with the DM method (0.006 +/- 0.003 versus 0.036 +/- 0.022, p < 0.001) for all study subjects. These results indicate that the new ACR method is useful for removing nonstationary tissue motion while improving the image quality for visualizing 3D vascular structure in 3D CDI.

  18. Diffusion-weighted Magnetic Resonance Imaging in the Diagnosis of Bone Tumors: Preliminary Results

    Directory of Open Access Journals (Sweden)

    Yeliz Pekcevik

    2013-01-01

    Full Text Available Objective: The study aims to determine whether apparent diffusion coefficient (ADC can help differentiate benign and malignant bone tumors. Materials and Methods: From January 2012 to February 2013, we prospectively included 26 patients. Of these 15 patients were male and 11 were female; ranging in age from 8 to 76 years (mean age, 34.5 years. Diffusion-weighted magnetic resonance (MR imaging was obtained with a single-shot echo-planar imaging sequence using a 1.5T MR scanner. We grouped malignant lesions as primary, secondary, and primary tumor with chondroid matrix. The minimum ADC was measured in the tumors and mean minimum ADC values were selected for statistical analysis. ADC values were compared between malignant and benign tumors using the Mann-Whitney U-test and receiver operating curve analysis were done to determine optimal cut-off values. Results: The mean ADC values from the area with lowest ADC values of benign and malignant tumors were 1.99 ± 0.57 × 10−3 mm 2 /s and 1.02 ± 1.0 × 10−3 mm 2 /s, respectively. The mean minimum ADC values of benign and malignant tumors were statistically different (P = 0.029. With cut-off value of 1.37 (10−3 mm 2 /s, sensitivity was 77.8% and specificity was 82.4%, for distinguishing benign and malignant lesion. Benign and secondary malignant tumors showed statistically significant difference (P = 0.002. There was some overlap in ADC values between benign and malignant tumors. The mean minimum ADC values of benign and malignant chondroid tumors were high. Giant cell tumor, non-ossifying fibroma and fibrous dysplasia showed lower ADC values. Conclusion: Although there is some overlap, ADC values of benign and malignant bone tumors seem to be different. Further studies with larger patient groups are needed to find an optimal cut-off ADC value.

  19. Effectiveness of diffusion tensor imaging in assessing disease severity in Duchenne muscular dystrophy: preliminary study

    Energy Technology Data Exchange (ETDEWEB)

    Ponrartana, Skorn; Hu, Houchun Harry [Children' s Hospital Los Angeles, Department of Radiology, Los Angeles, CA (United States); Ramos-Platt, Leigh [Children' s Hospital Los Angeles, Department of Neurology, Los Angeles, CA (United States); Wren, Tishya Anne Leong; Gilsanz, Vicente [Children' s Hospital Los Angeles, Department of Radiology, Los Angeles, CA (United States); Children' s Hospital Los Angeles, Department of Orthopaedic Surgery, Los Angeles, CA (United States); Perkins, Thomas Gardner; Chia, Jonathan Mawlin [Philips Healthcare North America, Cleveland, OH (United States)

    2015-04-01

    There is currently a lack of suitable objective endpoints to measure disease progression in Duchenne muscular dystrophy (DMD). Emerging research suggests that diffusion tensor imaging (DTI) has potential as an outcome measure for the evaluation of skeletal muscle injury. The objective of this study was to evaluate the potential of DTI as quantitative magnetic resonance imaging (MRI) markers of disease severity in DMD. Thirteen consecutive boys (8.9 years ± 3.0 years) with DMD were evaluated using DTI. Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were compared with clinical outcome measures of manual muscle testing and MRI determinations of muscle fat fraction (MFF) in the right lower extremity. Both MRI measures of FA and ADC strongly correlated with age and muscle strength. Values for FA positively correlated with age and negatively correlated with muscle strength (r = 0.78 and -0.96; both P ≤ 0.002) while measures of ADC negatively correlated age, but positively correlated with muscle strength (r = -0.87 and 0.83; both P ≤ 0.0004). Additionally, ADC and FA strongly correlated with MFF (r = -0.891 and 0.894, respectively; both P ≤ 0.0001). Mean MMF was negatively correlated with muscle strength (r = -0.89, P = 0.0001). DTI measures of muscle structure strongly correlated with muscle strength and adiposity in boys with DMD in this pilot study, although these markers may be more reflective of fat replacement rather than muscle damage in later stages of the disease. Further studies in presymptomatic younger children are needed to assess the ability of DTI to detect early changes in DMD. (orig.)

  20. Diffusion tensor imaging and fiber tractography in cervical compressive myelopathy: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Joon Woo; Kim, Jae Hyoung; Park, Jong Bin; Lee, Guen Young; Kang, Heung Sik [Seoul National University Bundang Hospital, Department of Radiology, Gyeonggi-do (Korea, Republic of); Park, Kun Woo; Yeom, Jin S. [Seoul National University Bundang Hospital, Department of Orthopaedic Surgery, Gyeonggi-Do (Korea, Republic of)

    2011-12-15

    To assess diffusion tensor imaging (DTI) parameters in cervical compressive myelopathy (CCM) patients compared to normal volunteers, to relate them with myelopathy severity, and to relate tractography patterns with postoperative neurologic improvement. Twenty patients suffering from CCM were prospectively enrolled (M:F = 13:7, mean age, 49.6 years; range 22-67 years) from September 2009 to March 2010. Sensitivity encoding (SENSE) single-shot echo-planar imaging (EPI) was used for the sagittal DTI. Twenty sex- and age-matched normal volunteers underwent the same scanning procedure. Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values in the spinal cord were compared between the patients and normal volunteers and were related to myelopathy severity based on Japanese Orthopedic Association (JOA) scores. Tractography patterns were related to myelopathy severity and postoperative improvement. There were significant differences between patients and normal volunteers in terms of FA (0.498 {+-} 0.114 vs. 0.604 {+-} 0.057; p = 0.001) and ADC (1.442 {+-} 0.389 vs. 1.169 {+-} 0.098; p = 0.001). DTI parameters and tractography patterns were not related to myelopathy severity. In ten patients in the neurologically worse group, postoperative neurologic improvement was seen in four of five patients with intact fiber tracts, but only one of five patients with interrupted fiber tracts exhibited neurologic improvement. DTI parameters in CCM patients were significantly different from those in normal volunteers but were not significantly related to myelopathy severity. The patterns of tractography appear to correlate with postoperative neurologic improvement. (orig.)

  1. Nitrogen Limitation Along The Kalahari Transect: Preliminary Results From A Stable Isotope Fertilization Experiment

    Science.gov (United States)

    Wang, L.; Macko, S.; D'Odorico, P.; Ries, L.

    2005-12-01

    Globally, savannas cover ~ 20% of the Earth's land area. Nutrients and soil moisture interactively control vegetation dynamics in many savannas although it is unclear how the relative importance of water and nutrient limitations (especially nitrogen) change with the mean climatic conditions. The Kalahari Transect (KT) in southern Africa traverses a dramatic aridity gradient (from ~ 200 mm to more than 1000 mm of mean annual precipitation (MAP), through the Republic of South Africa, Botswana, Namibia and Zambia), on relatively homogenous soils (deep Kalahari sands). This transect offers the ideal setting to study nutrient and vegetation dynamics without confounding soil effects. To improve the understanding of nitrogen and water controls on savanna vegetation, this study tested the hypothesis that the savannas in the Kalahari switch from conditions of water limitation in the dry areas to nutrient limitation in the wet areas. To this end, we conducted a large-scale stable isotope fertilization experiment using four study sites with different MAP. The transect included sites in Mongu, Zambia (MAP ~950mm), Pandamatenga, Ghanzi, and Tshane, Botswana with MAP ranging between 700 mm and 300 mm. The experimental design consisted of a randomized block design with four 21 m x 13 m plots at each site. Each plot was divided into four 10 m x 6 m subplots with 1 m buffer zone between each subplot. Four treatments (N addition, P addition, N+P addition and control) were randomly applied to the subplots. The experiment began during the dry season, in August, 2004, when 39g/m2 of Ca(NO3)2 (3.3g-N/ m2 ) was evenly applied to the N and N+P subplots, and 7.5g/m2 of Ca(H2PO4)2 (1.7g-P/m2) was applied to the P and N+P subplots, while the control subplots were left with no treatment. The N and N+P additions were enriched with 15N (Ca(15NO3)2 ) to a signature of 10.3 ‰. Before application, soil samples from two different layers (0cm and 50cm) outside the plots and foliar samples of the

  2. Preliminary experience using transthoracic echocardiography guiding percutaneous closure of ruptured right sinus of Valsalva aneurysm

    Institute of Scientific and Technical Information of China (English)

    LI Yue; WANG Guang-yi; WANG Zhi-feng; GUO Liang

    2011-01-01

    Background In the 21st century, minimally invasive treatment is one of the main developmental directions of medical sciences. It is well known that the echocardiography plays an important role during interventional treatments of some structural heart diseases. Because the ruptured right sinus of the Valsalva aneurysm (RRSVA) is a rare disease, there were few reports about percutaneous catheter closure of RRSVA. This study aimed to sum up our experience with transthoracic echocardiography (TTE) during percutaneous catheter closure of RRSVA.Methods Five RRSVA cases were treated with percutaneous catheter closure. The whole procedure was guided and monitored by TTE and fluoroscopy. The maximum diameter of the RRSVA was measured by TTE before and after the catheter passed through the rupture site. A duct occluder 2 mm larger than the maximum diameter was chosen. The closure effects were evaluated with TTE and fluoroscopy immediately after the occluding device was deployed. All patients were followed up by TTE for 8 to 30 months.Results Before the catheter passed through the rupture site the maximum diameter of the RRSVA measured with TTE and aortography were (7.9 ±2.1) mm and (7.8 ± 1.8) mm. After the catheter passed through the rupture site the maximum diameter measured with TTE was (11.2 ± 3.2) mm, which was significantly larger than before the procedure (P <0.05). The percutaneous catheter closure was successful in four cases and failed in one. Compared to the aortography the TTE was better at distinguishing residual shunts from aortic valve regurgitation immediately after the occluding device was deployed. There were no complications during 8 to 30 months of follow-up.Conclusion Transthoracic echocardiography can play an important role during percutaneous catheter closure of RRSVA,especially for estimating the size of the RRSVA after the catheter passes through the rupture site, and differentiating residual shunt from aortic valve regurgitation immediately

  3. Staff empowerment: a medical record department's preliminary experiences with continuous quality improvement.

    Science.gov (United States)

    Markon, E

    1992-11-01

    After observing the results of continuous quality improvement, no one would argue against its value in the workplace. However, learning to apply the concepts requires change on everyone's part, and the challenge lies in effecting this change. Not everyone will want to work in this type of environment and, if the organization is truly committed to continuous quality improvement, those individuals may have to make hard decisions as to whether the organization is the right place for them to work. Certain skills are required for staff empowerment to be successful, and training in these skills is essential. The medical record department staff learned early in this process that, although the group possessed job skills, interaction and team skills were lacking. The Development Dimensions International program helped the managers and staff identify the weaknesses of the group and provided educational tools for improvement. The changes often are so subtle, the group does not realize anything has changed. It was not until recently, when the medical record department staff was requested by administration to identify department quality improvement projects, that the group looked back at where the process started and realized how different things are today from three years ago--now staff members lead team meetings, work-groups are redesigning their job processes, and teams update the rest of the department staff on its progress at department meetings. Everyone expressed a sense of pride and accomplishment that the group had indeed responded to the challenge. The experiences of the medical record department thus far clearly support empowerment of employees.(ABSTRACT TRUNCATED AT 250 WORDS)

  4. Fetal reduction by bipolar cord coagulation in managing complicated monochorionic multiple pregnancies: preliminary experience in China

    Institute of Scientific and Technical Information of China (English)

    HE Zhi-ming; FANG Qun; YANG Yong-zhong; LUO Yan-min; CHEN Jun-hong; CHEN Yong-zhen; ZHOU Yi; CHEN Min-ling

    2010-01-01

    Background Monochorionic multiple pregnancies (MMPs) are associated with higher rates of perinatal morbidity and mortality caused by interfetal vascular anastomoses in the monochorionic placenta, which can lead to fetal health interactions. In some circumstances, selective feticide of the affected fetus is necessary to save the healthy co-twin. We evaluated the effects and safety of our initial experiences using bipolar cord coagulation for the management of complicated MMPs. Methods Using ultrasound-guided bipolar cord coagulation, we performed selective feticide on 14 complicated MMPs (5 with twin-twin transfusion syndrome, 4 with acardia, 3 with discordant structural anomalies, and 2 with severe selective intrauterine growth restriction). One patient with monochorionic triplets received the procedure twice to terminate 2 affected fetuses for different indications. Data regarding the operations, complications and neonatal outcomes were analyzed. Results Cord occlusions were successfully performed in 13/14 (93%) cases. The failure happened in an acardiac fetus and the pregnancy was terminated by induction. The included cases delivered at a mean gestational age of 35.4 weeks with a perinatal survival rate of 11/13 (85%). Three operation-related complications occurred (21%), including membrane rupture of the terminated sac (1 case), preterm labor at 28 weeks gestation (1 case), and chorioamniotic membrane separation (1 case). Amnioinfusion was indicated in 11 procedures to expand the target sacs for entering the trocar and obtaining sufficient working space. However, in all 4 cases of acardia, the acardiac sacs showed extreme oligohydramnios and could not be well expanded by infusion; thus, the trocar had to be inserted from the sac of the preserved co-twin. Conclusions The application of bipolar cord coagulation in complicated MMPs is safe and improves the prognosis. Amnioinfusion is useful in helping to expand the target sac when the working space is limited.

  5. Micromultileaf collimator-based stereotactic radiosurgery for selected arteriovenous malformations: Technique and preliminary experience

    Directory of Open Access Journals (Sweden)

    Jalali Rakesh

    2009-01-01

    Full Text Available Purpose : To report our experience of stereotactic radiosurgery (SRS in consecutively treated patients with arteriovenous malformations (AVMs. Materials and Methods : Of the 87 patients, 23 patients qualified and were treated with SRS as per predefined protocol according to AVM size, location, neurological status, prior bleeding, and the AVM score. All had Spletzer-Martin grade II/III and AVM scores < 2.5. Patients underwent SRS using micromultileaf collimators delivering multiple noncoplanar fixed fields. Doses were prescribed using the Flickinger model. Patients were followed up with magnetic resonance angiography (MRA and digitally subtracted angiography (DSA. Results : The mean nidus volume was 3.65 cc. The mean prescribed maximum dose was 22 Gy and the marginal dose was 19.24 Gy; 12 Gy normal brain volume was 8.39 cc and 12 Gy marginal volume was 5.03 cc. Mean dose to brain stem, pituitary hypothalamic axis, and optic chiasm was 2.5, 0.72, and 0.49 Gy, respectively. At a median follow-up of 22 months (range 1.5-71.2 months, 7 of 10 patients presenting with a neurological deficit showed significant improvement. All 15 patients who underwent MRA 1.5-2 years after SRS had no residual nidus yielding an MRA complete obliteration rate of 100%. Twelve patients also underwent a check DSA, which confirmed obliteration in 11 of them resulting in an accuracy of MRA of 92%. One patient after SRS had transient deterioration of motor power, which resolved completely after a short course of steroids and another had mild worsening of the hemiparesis. All patients are able to lead an active functional life. Conclusions : Careful selection of cases suitable for SRS provides optimum obliteration rates with low toxicity.

  6. Molten salt oxidation of mixed waste: Preliminary bench-scale experiments without radioactivity

    Energy Technology Data Exchange (ETDEWEB)

    Haas, P.A.; Rudolph, J.C.; Bell, J.T.

    1994-06-01

    Molten salt oxidation (MSO) is a process in which organic wastes are oxidized by sparging them with air through a bed of molten sodium carbonate (bp 851 {degrees}C) at {ge} 900{degrees}C. This process is readily applicable to the mixed waste because acidic products from Cl, S, P, etc., in the waste, along with most metals and most radionuclides, are retained within the melt as oxides or salts. Rockwell International has studied the application of MSO to various wastes, including some mixed waste. A unit used by Rockwell to study the mixed waste treatment is presently in use at Oak Ridge National Laboratory (ORNL). ORNL`s studies to date have concentrated on chemical flowsheet questions. Concerns that were studied included carbon monoxide (CO) emissions, NO{sub x}, emissions, and metal retention under a variety of conditions. Initial experiments show that CO emissions increase with increasing NaCl content in the melt, increasing temperature, and increasing airflow. Carbon monoxide content is especially high (> 2000 ppm) with high chlorine content (> 10%). Thermal NO{sub x}, emissions are relatively low ( < 5 ppm) at temperatures < 1000{degrees}C. However, most (85--100%) of the nitrogen in the feed as organic nitrate or amine was released as NO{sub x}, The metal contents of the melt and of knockout pot samples of condensed salt show high volatilities of Cs as CsCl. Average condensed salt concentrations were 60% for barium and 100% for strontium and cobalt. The cerium disappeared -- perhaps from deposition on the alumina reactor walls.

  7. Designing assisted living technologies ‘in the wild’: preliminary experiences with cultural probe methodology

    Directory of Open Access Journals (Sweden)

    Wherton Joseph

    2012-12-01

    , limited emotional or psychological resources, life events, and acute illness. Discussions between researchers and participants about the materials collected (and sometimes about what had prevented them completing the tasks helped elicit further information relevant to assisted living technology design. The probe materials were particularly helpful when having conversations with non-English speaking participants through an interpreter. Conclusions Cultural probe methods can help build a rich picture of the lives and experiences of older people to facilitate the co-production of assisted living technologies. But their application may be constrained by the participant’s physical, mental and emotional capacity. They are most effective when used as a tool to facilitate communication and development of a deeper understanding of older people’s needs.

  8. Preliminary results of acoustic radiation force impulses (ARFI) ultrasound imaging of solid suspicious breast lesions

    Institute of Scientific and Technical Information of China (English)

    Lei Ye; Liping Wang; Yuan Huang; Youbin Deng

    2013-01-01

    Objective: The aim of our study was to make the qualitative and quantitative analysis to breast lesions usingacoustic radiation force impulses (ARFI), and assess the diagnostic value of ARFI for differentiation between benign andmalignant solid breast masses, meanwhile evaluate the influences of ARFI with breast imaging reporting and data system(BI-RADS) of suspicious masses. Methods: Seventy-five women with 86 breast lesions underwent conventional breast ultrasoundexamination. Then B-mode BI-RADS features and assessments were recorded and standard breast US supplementedby ARFI elastographic examination were repeated. The data were recorded and analyzed as following: area ratio of breastlesion, the shear-wave velocity, the ratio of the shear-wave velocity between lesions and surrounding normal tissues, andaccording to the elastographic data reconsidered the BI-RADS category, all the results have been correlated with pathologicalresults and make statistical evaluations of ARFI for differentiation between benign and malignant solid breast masses.Meantime our study has correlated the adjusted BI-RADS category of suspicious breast lesions with the pathological resultsand made assessment. Results: Thirty-eight patients were malignant breast carcinoma (31 invasive ductal carcinoma, 5intraductal carcinoma in situ, 2 medullary carcinoma, 2 invasive lobular carcinoma), 48 patients were benign breast lesions(23 fibroadenoma, 12 benign nodular hyperplasia, 5 phyllodes tumor, 6 adenosis, 2 intraductal papilloma). Underwent conventionalbreast ultrasound exam, 42 cases were BI-RADS category 3, 23 cases were BI-RADS category 4. When addingelastographic data, 46 cases were BI-RADS category 3 and 20 cases were BI-RADS category 4. Compared with pathologicalresults showed for both the specificity of BIRADS features and the area under ROC curve has risen. Virtual touch tissue imaging(VTI) and virtual touch tissue quantification (VTQ) data showed the area ratio (AR) between

  9. Preliminary results of endorectal surface coil magnetic resonance imaging for local staging of prostate cancer

    Energy Technology Data Exchange (ETDEWEB)

    Jager, G.H. [Radiologische Universitaetsklinik, Nijmegen (Netherlands). Abt. fuer Abdominale Roentgendiagnostik; Barentsz, J.O. [Radiologische Universitaetsklinik, Nijmegen (Netherlands). Abt. fuer Abdominale Roentgendiagnostik; Rosette, J.J.M.C.H. de la [Medizinische Universitaetsklinik, Nijmegen (Netherlands). Abt. fuer Urologie; Rosenbusch, G. [Radiologische Universitaetsklinik, Nijmegen (Netherlands). Abt. fuer Abdominale Roentgendiagnostik

    1994-03-01

    Objective: To evaluate the effectiveness of endorectal surface coil (ERC) magnetic resonance imaging (MRI) in the local staging of adenocarcinoma of the prostate (ACP). Materials and methods: A total of 23 patients who were considered candidates for radical prostatectomy because of clinically localized ACP were examined by ERC-MRI. All patients underwent laparoscopic or open lymph-node dissection prior to surgery. Four patients had positive lymph nodes at operation. A total of 19 underwant radical prostatectomy, allowing comparison of the MRI data with the surgical pathologic findings. Results: Twelve patients had extraglandular spread of ACP (T3) and 7 had locally confined ACP (T2). ERC-MRI predicted correctly a T3 tumor in 10 of 12 cases and a T2 tumor in 4 of 7 cases. ERC-MRI was 74% accurate in differentiating T2 from T3 tumor. Three cases of overestimation were in studies with poor image quality because of bowel movement motion artifacts. Conclusion: ERC-MRI was found to be a sensitive modality in staging clinically localized ACP. (orig.) [Deutsch] Ziel: Bestimmung der Wertigkeit der Kernspintomographie (MRI) mit einer endorektalen Oberflaechenspule (ERC) fuer das lokale staging des Adenokarzinoms der Prostata (ACP). Material und Methode: Insgesamt 23 Patienten die als Kandidaten fuer eine radikale Prostatektomie wegen eines klinisch lokalisierten ACP galten, wurden mit ERC-MRI untersucht. Alle Patienten unterzogen sich einer laparoskopischen oder offenen Lymphdruesendissektion bei der Operation. Bei 19 Patienten, bei denen eine radikale Prostatektomie ausgefuehrt wurde, konnte eine Korrelation der MRI-Befunde mit denen der Operation erfolgen. Ergebnisse: Zwoelf Patienten wiesen extraglandulaere Ausbreitung des ACP (T3) auf und 7 hatten ein lokal begrenztes ACP (T2). ERC-MRI ergab korrekt einen T3-Tumor in 10 der 12 Faelle und einen T2-Tumor in 4 der 7 Faelle. Die Genauigkeit der ERC-MRI um einen T2- von einem T3-Tumor zu differenzieren betrug 74%. Bei drei

  10. Laser-induced dental caries and plaque diagnosis on patients by sensitive autofluorescence spectroscopy and time-gated video imaging: preliminary studies

    Science.gov (United States)

    Koenig, Karsten; Schneckenburger, Herbert

    1994-09-01

    The laser-induced in vivo autofluorescence of human teeth was investigated by means of time- resolved/time-gated fluorescence techniques. The aim of these studies was non-contact caries and plaque detection. Carious lesions and dental plaque fluoresce in the red spectral region. This autofluorescence seems to be based on porphyrin-producing bacteria. We report on preliminary studies on patients using a novel method of autofluorescence imaging. A special device was constructed for time-gated video imaging. Nanosecond laser pulses for fluorescence excitation were provided by a frequency-doubled, Q-switched Nd:YAG laser. Autofluorescence was detected in an appropriate nanosecond time window using a video camera with a time-gated image intensifier (minimal time gate: 5 ns). Laser-induced autofluorescence based on porphyrin-producing bacteria seems to be an appropriate tool for detecting dental lesions and for creating `caries-images' and `dental plaque' images.

  11. White matter integrity in Asperger syndrome: a preliminary diffusion tensor magnetic resonance imaging study in adults.

    Science.gov (United States)

    Bloemen, Oswald J N; Deeley, Quinton; Sundram, Fred; Daly, Eileen M; Barker, Gareth J; Jones, Derek K; van Amelsvoort, Therese A M J; Schmitz, Nicole; Robertson, Dene; Murphy, Kieran C; Murphy, Declan G M

    2010-10-01

    Autistic Spectrum Disorder (ASD), including Asperger syndrome and autism, is a highly genetic neurodevelopmental disorder. There is a consensus that ASD has a biological basis, and it has been proposed that it is a "connectivity" disorder. Diffusion Tensor Magnetic Resonance Imaging (DT-MRI) allows measurement of the microstructural integrity of white matter (a proxy measure of "connectivity"). However, nobody has investigated the microstructural integrity of whole brain white matter in people with Asperger syndrome. We measured the fractional anisotropy (FA), mean diffusivity (MD) and radial diffusivity (RD) of white matter, using DT-MRI, in 13 adults with Asperger syndrome and 13 controls. The groups did not differ significantly in overall intelligence and age. FA, MD and RD were assessed using whole brain voxel-based techniques. Adults with Asperger syndrome had a significantly lower FA than controls in 13 clusters. These were largely bilateral and included white matter in the internal capsule, frontal, temporal, parietal and occipital lobes, cingulum and corpus callosum. Adults with Asperger syndrome have widespread significant differences from controls in white matter microstructural integrity.

  12. Preliminary study of slow and fast ultrasonic waves using MR images of trabecular bone phantom

    Energy Technology Data Exchange (ETDEWEB)

    Solis-Najera, S. E., E-mail: solisnajera@ciencias.unam.mx, E-mail: angel.perez@ciencias.unam.mx, E-mail: lucia.medina@ciencias.unam.mx; Neria-Pérez, J. A., E-mail: solisnajera@ciencias.unam.mx, E-mail: angel.perez@ciencias.unam.mx, E-mail: lucia.medina@ciencias.unam.mx; Medina, L., E-mail: solisnajera@ciencias.unam.mx, E-mail: angel.perez@ciencias.unam.mx, E-mail: lucia.medina@ciencias.unam.mx [Facultad de Ciencias, Universidad Nacional Autónoma de México, México, DF 04510 (Mexico); Garipov, R., E-mail: ruslan.garipov@mrsolutions.co.uk [MR Solutions Ltd, Surrey (United Kingdom); Rodríguez, A. O., E-mail: arog@xanum.uam.mx [Departamento Ingeniería Eléctrica, Universidad Autónoma Metropolitana Iztapalapa, México, DF 09340 (Mexico)

    2014-11-07

    Cancellous bone is a complex tissue that performs physiological and biomechanical functions in all vertebrates. It is made up of trabeculae that, from a simplified structural viewpoint, can be considered as plates and beams in a hyperstatic structure that change with time leading to osteoporosis. Several methods has been developed to study the trabecular bone microstructure among them is the Biot’s model which predicts the existence of two longitudinal waves in porous media; the slow and the fast waves, that can be related to porosity of the media. This paper is focused on the experimental detection of the two Biot’s waves of a trabecular bone phantom, consisting of a trabecular network of inorganic hydroxyapatite. Experimental measurements of both waves were performed using through transmission ultrasound. Results had shown clearly that the propagation of two waves propagation is transversal to the trabecular alignment. Otherwise the waves are overlapped and a single wave seems to be propagated. To validate these results, magnetic resonance images were acquired to assess the trabecular direction, and to assure that the pulses correspond to the slow and fast waves. This approach offers a methodology for non-invasive studies of trabecular bones.

  13. In vivo sodium (23Na) imaging of the human kidneys at 7 T: preliminary results.

    Science.gov (United States)

    Haneder, Stefan; Juras, Vladimir; Michaely, Henrik J; Deligianni, Xeni; Bieri, Oliver; Schoenberg, Stefan O; Trattnig, Siegfried; Zbýň, Štefan

    2014-02-01

    To evaluate the feasibility of in vivo (23)Na imaging of the corticomedullary (23)Na gradient and to measure (23)Na transverse relaxation times (T2*) in human kidneys. In this prospective, IRB-approved study, eight healthy volunteers (4 female, 4 male; mean age 29.4 ± 3.6 years) were examined on a 7-T whole-body MR system using a (23)Na-only spine-array coil. For morphological (23)Na-MRI, a 3D gradient echo (GRE) sequence with a variable echo time scheme (vTE) was used. T2* times were calculated using a multiecho 3D vTE-GRE approach. (23)Na signal-to-noise ratios (SNR) were given on a pixel-by-pixel basis for a 20-mm section from the cortex in the direction of the medulla. T2* maps were calculated by fitting the (23)Na signal decay monoexponentially on a pixel-by-pixel basis, using least squares fit. Mean corticomedullary (23)Na-SNR increased from the cortex (32.2 ± 5.6) towards the medulla (85.7 ± 16.0). The SNR increase ranged interindividually from 57.2% to 66.3%. Mean (23)Na-T2* relaxation times differed statistically significantly (P pyramid direction. • In vivo measurements of renal (23) Na-T2* times are demonstrated at 7.0 T.

  14. Separating Morphologically Similar Pollen Types Using Basic Shape Features from Digital Images: A Preliminary Study

    Directory of Open Access Journals (Sweden)

    Katherine A. Holt

    2014-08-01

    Full Text Available Premise of the study: One of the many advantages offered by automated palynology systems is the ability to vastly increase the number of observations made on a particular sample or samples. This is of particular benefit when attempting to fully quantify the degree of variation within or between closely related pollen types. Methods: An automated palynology system (Classifynder has been used to further investigate the variation in pollen morphology between two New Zealand species of Myrtaceae (Leptospermum scoparium and Kunzea ericoides that are of significance in the New Zealand honey industry. Seven geometric features extracted from automatically gathered digital images were used to characterize the range of shape and size of the two taxa, and to examine the extent of previously reported overlap in these variables. Results: Our results indicate a degree of overlap in all cases. The narrowest overlap was in measurements of maximum Feret diameter (MFD in grains oriented in polar view. Multivariate statistical analysis using all seven factors provided the most robust discrimination between the two types. Discussion: Further work is required before this approach could be routinely applied to separating the two pollen types used in this study, most notably the development of comprehensive reference distributions for the types in question.

  15. Differentiating malignant vertebral tumours from non-malignancies with CT spectral imaging: a preliminary study

    Energy Technology Data Exchange (ETDEWEB)

    Yuan, Yuan; Zhang, Yan; Lang, Ning; Yuan, Huishu [Peking University Third Hospital, No.49 North Garden Street, Haidian District, Beijing (China); Li, Jianying [GE Healthcare, CT imaging Research Center, Beijing (China)

    2015-10-15

    To investigate the value of dual-energy spectral computed tomography (DESCT) for differentiating malignant vertebral tumours from non-malignancies during venous phase. This study was institutional review board-approved, and written informed consent was obtained from all patients. Thirty-seven patients were examined by DESCT during venous phase. Twenty patients had malignant vertebral tumours, 17 had non-malignant vertebral tumours. The iodine/water densities for the lesion, the lesion-to-muscle ratio, and lesion-to-artery ratio for iodine density measurements were calculated and compared between the two groups with the two-tailed Student t test. A p-value < 0.05 was considered statistically significant. Sensitivity and specificity were compared between the qualitative and quantitative studies. The iodine density, lesion-to-muscle ratio, and lesion-to-artery ratio of the iodine density measurement for malignant vertebral tumours were significantly different from the respective values for non-malignancies (all p < 0.05). Using 0.52 as the threshold value for the lesion-to-artery iodine density ratio, one could obtain sensitivity of 85 % and specificity of 100 % for differentiating malignant vertebral tumours from non-malignancies, significantly higher than the qualitative diagnosis. DESCT imaging enables analysis of a number of additional quantitative CT parameters to improve the accuracy for differentiating malignant vertebral tumours from non-malignancies during venous phase. (orig.)

  16. Resolution criteria in double-slit microscopic imaging experiments

    Science.gov (United States)

    You, Shangting; Kuang, Cuifang; Zhang, Baile

    2016-09-01

    Double-slit imaging is widely used for verifying the resolution of high-resolution and super-resolution microscopies. However, due to the fabrication limits, the slit width is generally non-negligible, which can affect the claimed resolution. In this paper we theoretically calculate the electromagnetic field distribution inside and near the metallic double slit using waveguide mode expansion method, and acquire the far-field image by vectorial Fourier optics. We find that the slit width has minimal influence when the illuminating light is polarized parallel to the slits. In this case, the claimed resolution should be based on the center-to-center distance of the double-slit.

  17. Our Experience with MR Imaging of Perianal Fistulas

    Science.gov (United States)

    Baskan, Ozdil; Koplay, Mustafa; Sivri, Mesut; Erol, Cengiz

    2014-01-01

    Summary Magnetic resonance imaging (MRI) depicts infectious foci in the perianal region better than any other imaging modality. MRI allows definition of the fistula, associated abscess formation and its secondary extensions. Accurate information is necessary for surgical treatment and to obtain a decrease in the incidence of recurrence and complications. Radiologists should be familiar with anatomical and pathological findings of perianal fistulas and classify them using the MRI – based grading system. The purpose of this article was to provide an overview for evaluation of perianal fistulas, examples of various fistula types and their classification. PMID:25550766

  18. Computer image processing - The Viking experience. [digital enhancement techniques

    Science.gov (United States)

    Green, W. B.

    1977-01-01

    Computer processing of digital imagery from the Viking mission to Mars is discussed, with attention given to subjective enhancement and quantitative processing. Contrast stretching and high-pass filtering techniques of subjective enhancement are described; algorithms developed to determine optimal stretch and filtering parameters are also mentioned. In addition, geometric transformations to rectify the distortion of shapes in the field of view and to alter the apparent viewpoint of the image are considered. Perhaps the most difficult problem in quantitative processing of Viking imagery was the production of accurate color representations of Orbiter and Lander camera images.

  19. Global atmospheric response to specific linear combinations of the main SST modes.. Part I: numerical experiments and preliminary results

    Science.gov (United States)

    Trzaska, S.; Moron, V.; Fontaine, B.

    1996-10-01

    This article investigates through numerical experiments the controversial question of the impact of El Niño-Southern Oscillation (ENSO) phenomena on climate according to large-scale and regional-scale interhemispheric thermal contrast. Eight experiments (two considering only inversed Atlantic thermal anomalies and six combining ENSO warm phase with large-scale interhemispheric contrast and Atlantic anomaly patterns) were performed with the Météo-France atmospheric general circulation model. The definition of boundary conditions from observed composites and principal components is presented and preliminary results concerning the month of August, especially over West Africa and the equatorial Atlantic are discussed. Results are coherent with observations and show that interhemispheric and regional scale sea-surface-temperature anomaly (SST) patterns could significantly modulate the impact of ENSO phenomena: the impact of warm-phase ENSO, relative to the atmospheric model intercomparison project (AMIP) climatology, seems stronger when embedded in global and regional SSTA patterns representative of the post-1970 conditions [i.e. with temperatures warmer (colder) than the long-term mean in the southern hemisphere (northern hemisphere)]. Atlantic SSTAs may also play a significant role. Acknowledgements. We gratefully appreciate the on-line DMSP database facility at APL (Newell et al., 1991) from which this study has benefited greatly. We wish to thank E. Friis-Christensen for his encouragement and useful discussions. A. Y. would like to thank the Danish Meteorological Institute, where this work was done, for its hospitality during his stay there and the Nordic Baltic Scholarship Scheme for its financial support of this stay. Topical Editor K.-H. Glassmeier thanks M. J. Engebretson and H. Lühr for their help in evaluating this paper.--> Correspondence to: A. Yahnin-->

  20. Inelastic neutron scattering experiments with the monochromatic imaging mode of the RITA-II spectrometer

    DEFF Research Database (Denmark)

    Bahl, Christian Robert Haffenden; Lefmann, Kim; Abrahamsen, Asger Bech;

    2006-01-01

    to perform real inelastic neutron scattering experiments. We present the results from inelastic powder, single crystal dispersion and single crystal constant energy mapping experiments. The advantages and complications of performing these experiments are discussed along with a comparison between the imaging...

  1. My 'Fat Girl Complex': a preliminary investigation of sexual health and body image in women of size.

    Science.gov (United States)

    Satinsky, Sonya; Dennis, Barbara; Reece, Michael; Sanders, Stephanie; Bardzell, Shaowen

    2013-01-01

    Women of size who inhabit non-normative bodies may have different experiences with body image and sexual health than women of average body size. In this exploratory study, we interviewed four women of size recruited from a larger mixed-methodological study of body image and sexuality. Each woman was interviewed twice on topics of body image, sexuality and sexual health. Reconstructive Horizon Analysis was used to analyse the content of the interviews. Women who expressed that their bodies had inherent personal and social value regardless of size did not articulate connections between body size and their sexual health. However, those women who looked externally for validation of their attractiveness struggled with acceptance of their sexuality and bodies and spoke of ways in which their body size and appearance hindered them from having the sexually healthy lives that they wanted. Findings highlight two important components of women's sexual health as participants related them to body image: the right to pleasure and the right to engage only in wanted sexual activity. Participants described how negative body attitudes affected both of these aspects of their sexual health. Interventions targeting weight-based stigma may offer a means of indirectly promoting sexual health and autonomy in women.

  2. Preliminary study on CT perfusion imaging in guiding biopsy of pulmonary lumps

    Institute of Scientific and Technical Information of China (English)

    KANG Li-qing; SONG Zhao-wei; LI Zhong-xin; YU Shu-jing; LIU Feng-hai; CHEN Yue-feng; XING Rong-ge

    2009-01-01

    Background CT perfusion imaging (CTP) has been proved to be a powerful functional imaging technique.This study aimed to evaluate the value of CTP in guiding biopsy of pulmonary lumps.Methods A total of 147 patients with pulmonary lumps who had CT guided biopsies were enrolled in this study from February 2005 to June 2007.The patients were assigned to 3 groups:33 cases guided by CTP as group Ⅰ,45 cases guided by contrast-enhanced scan of CT as group Ⅱ,and 69 cases guided by plain scan of CT as group Ⅲ.Each group was subdivided into central and peripheral types according to the location of the lumps.The achievement ratio of biopsy,the accuracy in grouping,and grading of lung cancer,and the incidence of complication were compared.Results The total achievement ratios of biopsy from group Ⅰ to Ⅲ were 100% (33/33),91% (41/45),and 80% (55/69)respectively,and the difference was statistically significant between group Ⅰ and Ⅲ (P <0.05).For the central type,they were 100% (18/18),88% (15/17),and 79% (11/14) respectively,and the difference was also statistically significant between group Ⅰ and Ⅲ (P <0.05).For the peripheral type,they were 100% (15/15),93% (26/28),and 80% (44/55) espectivelies,and the difference was not statistically significant among the three groups.The total accuracies in grouping and grading of lung cancer from group Ⅰ to Ⅲ were 100% (27/27),91% (31/34),and 72% (33/46) respectively,and the difference was statistically significant between group Ⅰ and Ⅲ and between group Ⅱ and III (P <0.05).For the central type,they were 100% (16/16),94% (16/17),and 70% (8/12) respectively,and the difference was statistically significant between group Ⅰ and Ⅲ (P <0.05).For the peripheral type,they were 100% (11/11),88% (15/17),and 72%(26/36) respectively,and the difference was statistically significant between group Ⅰ and Ⅲ (P <0.05).The total incidence of complication from group Ⅰ to Ⅲ were 15% (5/33),27% (12/45),and 43% (30

  3. Robotic image-guided reirradiation of lateral pelvic recurrences: preliminary results

    Directory of Open Access Journals (Sweden)

    Castelain Bernard

    2011-06-01

    Full Text Available Abstract Background The first-line treatment of a pelvic recurrence in a previously irradiated area is surgery. Unfortunately, few patients are deemed operable, often due to the location of the recurrence, usually too close to the iliac vessels, or the associated surgical morbidity. The objective of this study is to test the viability of robotic image-guided radiotherapy as an alternative treatment in inoperable cases. Methods Sixteen patients previously treated with radiotherapy were reirradiated with CyberKnife® for lateral pelvic lesions. Recurrences of primary rectal cancer (4 patients, anal canal (6, uterine cervix cancer (4, endometrial cancer (1, and bladder carcinoma (1 were treated. The median dose of the previous treatment was 45 Gy (EqD2 range: 20 to 96 Gy. A total dose of 36 Gy in six fractions was delivered with the CyberKnife over three weeks. The responses were evaluated according to RECIST criteria. Results Median follow-up was 10.6 months (1.9 to 20.5 months. The actuarial local control rate was 51.4% at one year. Median disease-free survival was 8.3 months after CyberKnife treatment. The actuarial one-year survival rate was 46%. Acute tolerance was limited to digestive grade 1 and 2 toxicities. Conclusions Robotic stereotactic radiotherapy can offer a short and well-tolerated treatment for lateral pelvic recurrences in previously irradiated areas in patients otherwise not treatable. Efficacy and toxicity need to be evaluated over the long term, but initial results are encouraging.

  4. Diffusion-weighted imaging in assessing renal pathology of chronic kidney disease: A preliminary clinical study

    Energy Technology Data Exchange (ETDEWEB)

    Li, Qinghai; Li, Jinning; Zhang, Lan; Chen, Ying; Zhang, Minming [Department of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009 (China); Yan, Fuhua, E-mail: zemylife@163.com [Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025 (China)

    2014-05-15

    Objective: To investigate the clinical potential of diffusion-weighted imaging (DWI) in assessing renal pathology of chronic kidney disease (CKD). Methods: Seventy-one CKD patients and twelve healthy volunteers were examined using DWI with prospective acquisition correction. Renal biopsy specimens from the CKD patients were scored based on the severity of renal pathology and to confirm pathology type. CKD patients were divided into three groups according to pathology scores: mild, moderate, or severe. The association between renal apparent diffusion coefficient (ADC) values and pathology scores was investigated using Pearson's correlation and single factor analysis of variance. Multiple linear regression analysis was performed to explore associations between renal ADC values and pathology score, glomerular filtration rate, serum creatinine, and age. The Kruskal–Wallis H test was conducted to compare ADC values and pathology type. Results: Renal ADC values correlated negatively with pathology scores (r = −0.633, P < 0.001). The ADC values among the four groups (mild, moderate, severe impairment, and controls) were significantly different (F = 19.512, P < 0.001). However, when patients were stratified by pathology type, no significant differences were found in ADC values among these groups (χ{sup 2} = 9.929, P = 0.270). Further multiple linear regression analysis showed that only the pathology score and ADC values were related (t = −4.586, P = 0.000). Conclusions: DWI has clinical potential in assessing the severity of renal pathology in CKD and shows promise as a non-invasive and effective technique to guide therapy and follow-up.

  5. Imaging of pulmonary disease in rheumatoid arthritis using JOO1X scintigraphy: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Goupille, P. [Service de Rhumatologie, Hopital Trousseau, Tours (France); Diot, P. [Service de Pneumologie, Hopital Bretonneau, Tours (France); Valat, J.P. [Service de Rhumatologie, Hopital Trousseau, Tours (France); Lemarie, E. [Service de Pneumologie, Hopital Bretonneau, Tours (France); Valat, C. [Service de Medecine Nucleaire, Hopital Bretonneau, Tours (France); Asquier, E. [Service de Radiologie, Hopital Bretonneau, Tours (France); Delarue, A. [Centre de Developpement Pierre Fabre, Labege (France); Pape, A.L. [Lab. de Biophysique Cellulaire et RMN, INSERM U316, Univ. Tours (France)

    1995-12-01

    The purpose of this study was to determine the ability of technetium-99m J001X scintigraphy to image active pulmonary involvement in patients suffering from rheumatoid arthritis (RA). J001X is a fully characterized acylated poly(1,3)galactoside, isolated from Klebsiella membranes, which is able to bind recruited macrophages after aerosol administration. J001X scintigraphy was compared with high-resolution computed tomography (HRCT), pulmonary function tests (PFTs) and bronchoalveolar lavage (BAL) in 15 patients suffering from RA. Patients were considered to have pulmonary involvement when they had an interstitial syndrome on HRCT and a decrease of 20% in TCO/VE (transfer coefficient) on PFTs and/or an abnormal BAL (lymphocytosis higher than 20% and/or percentage of neutrophils higher than 10%). Pulmonary involvement was present in eight patients, and absent in seven. Of the eight patients with pulmonary involvement, all had abnormal BAL, two had an interstitial syndrome on HRCT, two had decreased TCO/VE and three had positive J001X scintigraphy. Of the seven patients without pulmonary involvement, six had normal BAL (not available in one), two had an interstitial syndrome on HRCT, one had decreased TCO/VE and two had positive J001X scintigraphy. According to our gold standard of pulmonary involvement, the sensitivity of J001X scintigraphy for the detection of pulmonary involvement in RA was 37.5%, the specificity was 71.4% and the positive predictive value was 60%. The ability of J001X scintigraphy to detect active pulmonary involvement during RA appears unclear in this study but it may detect processes unnoticed by the other modalities. (orig./MG)

  6. MR imaging-guided prostate biopsy: technical features and preliminary results.

    Science.gov (United States)

    Panebianco, Valeria; Barchetti, Flavio; Manenti, Guglielmo; Aversa, Tommaso; Catalano, Carlo; Simonetti, Giovanni

    2015-06-01

    Repeatedly negative prostate biopsies in individuals with elevated prostate-specific antigen (PSA) levels can be frustrating for both the patient and the urologist. This study was performed to investigate if magnetic resonance imaging (MRI)-guided transrectal biopsy (MRGB) increases diagnostic performance in individuals with suspected prostate cancer (PCa). Twenty-three consecutive men with a total PSA >4 ng/mL, PSA density >0.15, PSA velocity >0.75 ng/mL/year and suspicious MRI findings were included (average age 64 years; age range 53-75 years; total PSA levels ranging from 4.7 to 54 ng/mL; median 9 ng/mL). MRGB was performed with a closed unit at 1.5 Tesla, an MRI compatible biopsy device, a needle guide, and a titanium double-shoot biopsy gun. At prebiopsy MRI, in the 23 patients, a total of 26 suspicious areas to which the MRGB should be directed were found, 23 of them in the peripheral zone and three in the transitional zone. The needle guide was depicted and could be positioned with MRI guidance in all 23 patients. The duration of the procedure ranged from 35 to 55 min (mean 40 min). MRGB was well tolerated by all patients, and no major complications were observed. The detection rate for the diagnosis of PCa was 80, and 90 % of detected PCa were of intermediate aggressiveness. MRGB has the potential to improve cancer detection rates in men with suspected PCa to deliver the relevant treatment as soon as possible.

  7. Cardiac biplane strain imaging: initial in vivo experience.

    NARCIS (Netherlands)

    Lopata, R.G.P.; Nillesen, M.M.; Verrijp, C.N.; Singh, S.K.; Lammens, M.M.Y.; Laak, J.A.W.M. van der; Wetten, H.B. van; Thijssen, J.M.; Kapusta, L.; Korte, C.L. de

    2010-01-01

    In this study, first we propose a biplane strain imaging method using a commercial ultrasound system, yielding estimation of the strain in three orthogonal directions. Secondly, an animal model of a child's heart was introduced that is suitable to simulate congenital heart disease and was used to

  8. Three-tesla imaging of the knee: initial experience

    Energy Technology Data Exchange (ETDEWEB)

    Craig, Joseph G.; Blechinger, Joseph; Hearshen, David; Bouffard, J. Antonio; Diamond, Mark; Holsbeeck, Marnix T. van [Henry Ford Hospital, Department of Diagnostic Radiology, Detroit, MI (United States); Go, Lily [Wayne State University School of Medicine, Detroit, MI (United States)

    2005-08-01

    To assess 3-T imaging of the knee. We reviewed 357 3-T magnetic resonance images of the knee obtained using a dedicated knee coil. From 58 patients who had arthroscopy we determined the sensitivity and specificity for anterior cruciate ligament (ACL) tear and medial and lateral meniscal tear. A chemical shift artifact showed prominently at 3 T even after improvements had been made by increasing the bandwidth. For complete ACL tear the sensitivity was 100% (95% confidence interval, CI, 75.30-100.00), and the specificity was 97.9% (95% CI 87.7-99.9). For the medial meniscus the sensitivity was 100.00% (95% CI 90.0-100.00), and the specificity was 83.3%(95% CI 66.6-95.3). For the lateral meniscus the sensitivity was 66.7% (95% CI 38.4-88.2), and the specificity was 97.6% (95% CI 87.1-99.9). In general 3-T imaging allows a favorable display of anatomy and pathology. The lateral meniscus was assessed to be weaker than the other anatomic structures. Three-tesla imaging allows increased signal-to-noise ratio, increased resolution, and faster scanning times. (orig.)

  9. TRAUMA (RE-)IMAG(IN)ED: EXPERIENCES AND MEMORIES OF ...

    African Journals Online (AJOL)

    imitch

    terms what trauma is, and interfaces it with how Soyinka has (re-)imag(in)ed it and submits ... innermost and visceral thoughts and being of his characters. .... Like The Man Died, Madmen and Specialists arose from Soyinka's painful and traumatic acquaintance ... out of the period, which I stayed in prison, which was just over.

  10. Magnetic resonance imaging spatial and time study of lung water content in newborn lamb: methods and preliminary results.

    Science.gov (United States)

    Viard, Romain; Tourneux, Pierre; Storme, Laurent; Girard, Julie-Marie; Betrouni, Nacim; Rousseau, Jean

    2008-06-01

    To study the lung liquid clearance in vivo at the time of birth, magnetic resonance experiments were conducted on newborn lambs immediately after uterine incision deliverance. Images obtained with a fast spin echo magnetic resonance imaging sequence enable to quantify lung liquid each 5 minutes for 30 minutes, then each 10 minutes for 1.5 hours. After manually determining lung contours, pulmonary volume, pulmonary water, and spatial gradient of pulmonary water were studied. At 2 hours of life, the total pulmonary water content was still high and the liquid clearance was slower in the lower part of the lung. Air inflation increased the size of the distal airways and shifted liquid from the lung lumen towards the pulmonary interstitial tissue. The lung liquid washout was belated, and the passage to the aerial life was performed by progressive liberation of the superior pulmonary spaces, water flowing out by gravity toward the lower spaces.

  11. Dynamic pelvic floor MR imaging at 3 T in patients with clinical signs of urinary incontinence-preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Morakkabati-Spitz, Nuschin; Willinek, Winfried A.; Traeber, Frank; Jaeger, Ursula; Schild, Hans H. [University of Bonn, Department of Radiology, Bonn (Germany); Gieseke, Juergen [University of Bonn, Department of Radiology, Bonn (Germany); Philips Medical Systems, Best (Netherlands); Bastian, Patrick J. [University of Munich, Department of Urology, Munich (Germany); Schmitz, Bettina; Mueller, Stefan C. [University of Bonn, Department of Urology, Bonn (Germany)

    2008-11-15

    . Dynamic pelvic floor MR imaging is feasible at 3.0 T. Our preliminary data indicate that evaluation of pelvic floor disease seems to be possible with 3.0 T equally well as compared to 1.5 T. (orig.)

  12. Evaluating the intensity of the acoustic radiation force impulse (ARFI) in intravascular ultrasound (IVUS) imaging: Preliminary in vitro results.

    Science.gov (United States)

    Shih, Cho-Chiang; Lai, Ting-Yu; Huang, Chih-Chung

    2016-08-01

    The ability to measure the elastic properties of plaques and vessels is significant in clinical diagnosis, particularly for detecting a vulnerable plaque. A novel concept of combining intravascular ultrasound (IVUS) imaging and acoustic radiation force impulse (ARFI) imaging has recently been proposed. This method has potential in elastography for distinguishing between the stiffness of plaques and arterial vessel walls. However, the intensity of the acoustic radiation force requires calibration as a standard for the further development of an ARFI-IVUS imaging device that could be used in clinical applications. In this study, a dual-frequency transducer with 11MHz and 48MHz was used to measure the association between the biological tissue displacement and the applied acoustic radiation force. The output intensity of the acoustic radiation force generated by the pushing element ranged from 1.8 to 57.9mW/cm(2), as measured using a calibrated hydrophone. The results reveal that all of the acoustic intensities produced by the transducer in the experiments were within the limits specified by FDA regulations and could still displace the biological tissues. Furthermore, blood clots with different hematocrits, which have elastic properties similar to the lipid pool of plaques, with stiffness ranging from 0.5 to 1.9kPa could be displaced from 1 to 4μm, whereas the porcine arteries with stiffness ranging from 120 to 291kPa were displaced from 0.4 to 1.3μm when an acoustic intensity of 57.9mW/cm(2) was used. The in vitro ARFI images of the artery with a blood clot and artificial arteriosclerosis showed a clear distinction of the stiffness distributions of the vessel wall. All the results reveal that ARFI-IVUS imaging has the potential to distinguish the elastic properties of plaques and vessels. Moreover, the acoustic intensity used in ARFI imaging has been experimentally quantified. Although the size of this two-element transducer is unsuitable for IVUS imaging, the

  13. Evaluation of tumour necrosis during chemotherapy with diffusion-weighted MR imaging: preliminary results in osteosarcomas

    Energy Technology Data Exchange (ETDEWEB)

    Uhl, Markus; Saueressig, Ulrich; Bley, Thorsten; Langer, Mathias [University Hospital, Department of Radiology, Freiburg (Germany); Koehler, Gabriele [University Hospital, Department of Pathology, Freiburg (Germany); Kontny, Udo [University Hospital, Children' s Hospital, Freiburg (Germany); Niemeyer, Charlotte [University Hospital, Department of Paediatric Oncology, Freiburg (Germany); Reichardt, Wilfried; Ilyasof, Kamil [University Hospital, Department of Medical Physics, Freiburg (Germany)

    2006-12-15

    During successful chemotherapy of osteosarcomas tumour size does not diminish significantly because the therapy has limited impact on the mineralized matrix of the tumour. Treatment response is considered successful if, histologically, more than 90% of tumour cells show necrosis. To determine if osteosarcomas change their water diffusion during preoperative chemotherapy in relation to the amount of tumour necrosis. Eight patients (age 11-19 years) with histologically proven limb osteosarcoma underwent T1-weighted, fat-suppressed T2-weighted and contrast-enhanced T1-weighted spin-echo imaging together with diffusion-weighted EPI sequences (b = 700) at 1.5 T before and after five cycles of standard chemotherapy. Tumour volume and apparent diffusion coefficient (ADC) maps were calculated before and after chemotherapy. The degree of tumour necrosis after chemotherapy was assessed using the histological Salzer-Kuntschik classification (grades 1-6). During chemotherapy, the ADC values of osteosarcomas changed significantly. The ADC of untreated tumour was 2.1 {+-} 0.4 x 10{sup -3} mm{sup 2}/s (mean {+-} SD) (95% CI 1.6-2.0). The ADC of chemotherapy-treated sarcomas was 2.5 {+-} 0.4 x 10{sup -3} mm{sup 2}/s (95% CI 1.8-2.2). Necrotic areas, which were confirmed by macroscopic examination, showed ADC values up to 2.7 x 10{sup -3} mm{sup 2}/s. Four patients with little viable tumour tissue within the neoplasm (Salzer-Kuntschik grades 1-2) had an increase in ADC of 0.4 up to 0.7 x 10{sup -3} mm{sup 2}/s. Four patients with larger areas of viable tumour (Salzer-Kuntschik grade 4) showed a lesser increase in ADC of 0.0 up to 0.3 x 10{sup -3} mm{sup 2}/s. The differences in ADC values in tumour tissue before and after chemotherapy were highly significant (P = 0.01). During chemotherapy of osteosarcomas, tumour ADC changes are related to the degree of tumour necrosis. (orig.)

  14. Preliminary energy-filtering neutron imaging with time-of-flight method on PKUNIFTY: A compact accelerator based neutron imaging facility at Peking University

    Science.gov (United States)

    Wang, Hu; Zou, Yubin; Wen, Weiwei; Lu, Yuanrong; Guo, Zhiyu

    2016-07-01

    Peking University Neutron Imaging Facility (PKUNIFTY) works on an accelerator-based neutron source with a repetition period of 10 ms and pulse duration of 0.4 ms, which has a rather low Cd ratio. To improve the effective Cd ratio and thus improve the detection capability of the facility, energy-filtering neutron imaging was realized with the intensified CCD camera and time-of-flight (TOF) method. Time structure of the pulsed neutron source was firstly simulated with Geant4, and the simulation result was evaluated with experiment. Both simulation and experiment results indicated that fast neutrons and epithermal neutrons were concentrated in the first 0.8 ms of each pulse period; meanwhile in the period of 0.8-2.0 ms only thermal neutrons existed. Based on this result, neutron images with and without energy filtering were acquired respectively, and it showed that detection capability of PKUNIFTY was improved with setting the exposure interval as 0.8-2.0 ms, especially for materials with strong moderating capability.

  15. Preliminary energy-filtering neutron imaging with time-of-flight method on PKUNIFTY: A compact accelerator based neutron imaging facility at Peking University

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Hu; Zou, Yubin, E-mail: zouyubin@pku.edu.cn; Wen, Weiwei; Lu, Yuanrong; Guo, Zhiyu

    2016-07-01

    Peking University Neutron Imaging Facility (PKUNIFTY) works on an accelerator–based neutron source with a repetition period of 10 ms and pulse duration of 0.4 ms, which has a rather low Cd ratio. To improve the effective Cd ratio and thus improve the detection capability of the facility, energy-filtering neutron imaging was realized with the intensified CCD camera and time-of-flight (TOF) method. Time structure of the pulsed neutron source was firstly simulated with Geant4, and the simulation result was evaluated with experiment. Both simulation and experiment results indicated that fast neutrons and epithermal neutrons were concentrated in the first 0.8 ms of each pulse period; meanwhile in the period of 0.8–2.0 ms only thermal neutrons existed. Based on this result, neutron images with and without energy filtering were acquired respectively, and it showed that detection capability of PKUNIFTY was improved with setting the exposure interval as 0.8–2.0 ms, especially for materials with strong moderating capability.

  16. Thermal energy storage in aquifiers: preliminary information

    Energy Technology Data Exchange (ETDEWEB)

    Allen, R.D.

    1979-12-01

    Topics discussed include: conceptual designs; numerical modelling; field experiments; relevant technical information; feasibility studies; preliminary aquifer selection considerations; and preliminary design and operating considerations. (TFD)

  17. Resolution criteria in double-slit microscopic imaging experiments

    Science.gov (United States)

    You, Shangting; Kuang, Cuifang; Zhang, Baile

    2016-01-01

    Double-slit imaging is widely used for verifying the resolution of high-resolution and super-resolution microscopies. However, due to the fabrication limits, the slit width is generally non-negligible, which can affect the claimed resolution. In this paper we theoretically calculate the electromagnetic field distribution inside and near the metallic double slit using waveguide mode expansion method, and acquire the far-field image by vectorial Fourier optics. We find that the slit width has minimal influence when the illuminating light is polarized parallel to the slits. In this case, the claimed resolution should be based on the center-to-center distance of the double-slit. PMID:27640808

  18. Design Analysis of a Space Based Chromotomographic Hyperspectral Imaging Experiment

    Science.gov (United States)

    2010-03-01

    utilized rather than a refractive lens telescopes for several reasons [26]: • Mirrors do not introduce any chromatic aberration • Mirrors provide a... aberration , but coma and astigmatism are inherent [35]. Mirrors will not cause chromatic aberration , unlike lenses [21]. A field stop is also being used...on a 20 micron pixel pitch. Image Quality: Two times diffration-limited performance or better. Zero chromatic aberration . The collimated beam

  19. Experiments on the use of CCD's to detect photoelectron images

    Science.gov (United States)

    Choisser, J. P.

    1975-01-01

    Image tube design and processing requirements for building an ICCD are discussed. Work is under way at EVC for building an ICCD using the Fairchild CCD 201 (100 x 100) array, and progress will be reported. Demountable tests have been made, exposing parts of a CCD 201 to 15 kilovolt electrons over five radiation levels from approximately 10 to 1 million rads. Other tubes built by EVC over the last few years which successfully use semiconductors to detect photoelectrons will be described briefly.

  20. Micro-Imagers for Spaceborne Cell-Growth Experiments

    Science.gov (United States)

    Behar, Alberto; Matthews, Janet; SaintAnge, Beverly; Tanabe, Helen

    2006-01-01

    A document discusses selected aspects of a continuing effort to develop five micro-imagers for both still and video monitoring of cell cultures to be grown aboard the International Space Station. The approach taken in this effort is to modify and augment pre-existing electronic micro-cameras. Each such camera includes an image-detector integrated-circuit chip, signal-conditioning and image-compression circuitry, and connections for receiving power from, and exchanging data with, external electronic equipment. Four white and four multicolor light-emitting diodes are to be added to each camera for illuminating the specimens to be monitored. The lens used in the original version of each camera is to be replaced with a shorter-focal-length, more-compact singlet lens to make it possible to fit the camera into the limited space allocated to it. Initially, the lenses in the five cameras are to have different focal lengths: the focal lengths are to be 1, 1.5, 2, 2.5, and 3 cm. Once one of the focal lengths is determined to be the most nearly optimum, the remaining four cameras are to be fitted with lenses of that focal length.

  1. Chest wall tuberculosis - A clinical and imaging experience

    Directory of Open Access Journals (Sweden)

    Shabnam Bhandari Grover

    2011-01-01

    Full Text Available Aims: Tuberculous infection of the thoracic cage is rare and is difficult to discern clinically or on radiographs. This study aims to describe the common sites and the imaging appearances of chest wall tuberculosis. Materials and Methods: A retrospective review of the clinical and imaging records of 12 confirmed cases of thoracic cage tuberculosis (excluding that of the spine, seen over the last 7 years, was performed. Imaging studies available included radiographs, ultrasonographies (USGs, and computed tomography (CT scans. Pathological confirmation was obtained in all cases. Results: All patients had clinical signs and symptoms localized to the site of involvement, whether it was the sternum, sternoclavicular joints, or ribs. CT scan revealed sternal destruction in three patients and osteolytic lesions with sclerosis of the articular surfaces of the sternoclavicular joints in two patients. In five patients with rib lesions, USG elegantly demonstrated the bone destruction underlying the cold abscess. All cases were confirmed to be of tuberculous origin by pathology studies of the aspirated/curetted material, obtained by CT / USG guidance. Conclusions: Tuberculous etiology should be considered for patients presenting with atypical sites of skeletal inflammation. CT scan plays an important role in the evaluation of these patients. However, the use of USG for demonstrating rib destruction in a chest wall cold abscess has so far been under-emphasized, as has been the role of CT and USG guided aspiration in confirming the aetiology.

  2. Electrical conductivity imaging of lower extremities using MREIT: postmortem swine and in vivo human experiments.

    Science.gov (United States)

    Woo, Eung Je; Kim, Hyung Joong; Minhas, Atul S; Kim, Young Tae; Jeong, Woo Chul; Kwon, O

    2008-01-01

    Cross-sectional conductivity images of lower extremities were reconstructed using Magnetic Resonance Electrical Impedance Tomography (MREIT) techniques. Carbon-hydrogel electrodes were adopted for postmortem swine and in vivo human imaging experiments. Due to their large surface areas and good contacts on the skin, we could inject as much as 10 mA into the lower extremities of human subjects without producing a painful sensation. Using a 3T MREIT system, we first performed a series of postmortem swine experiments and produced high-resolution conductivity images of swine legs. Validating the experimental protocol for the lower extremities, we revised it for the following human experiments. After the review of the Institutional Review Board (IRB), we conducted our first MREIT experiments of human subjects using the same 3T MREIT system. Collecting magnetic flux density data inside lower extremities subject to multiple injection currents, we reconstructed cross-sectional conductivity images using the harmonic B(z) algorithm. The conductivity images very well distinguished different parts of muscles inside the lower extremities. The outermost fatty layer was clearly shown in each conductivity image. We could observe severe noise in the outer layer of the bones primarily due to the MR signal void phenomenon there. Reconstructed conductivity images indicated that the internal regions of the bones have relatively high conductivity values. Future study is desired in terms of the conductivity image reconstruction algorithm to improve the image quality. Further human imaging experiments are planned and being conducted to produce high-resolution conductivity images from different parts of the human body.

  3. Immediate conversion to CAS after neurological intolerance at cross-clamping test during CEA: a preliminary experience.

    Science.gov (United States)

    Guy Bianchi, P; Tolva, V; Dalainas, I; Bertoni, G; Cireni, L; Trimarchi, S; Rampoldi, V; Casana, R

    2012-02-01

    The aim of this preliminary study is to evaluate the feasibility and efficacy of CAS as treatment option to endarterectomy when carotid shunt cannot be used safely. The medical records concerning 469 carotid stenosis treated between January 2006 and December 2009 were retrospectively reviewed, focusing on cross-clamp intolerance during CEA. Patients with cross-clamping intolerance were divided in two groups. Group 1: those that concluded the open procedure with the use of a shunt, and Group 2: those who experience immediate brain intolerance and coma and were immediately converted to an endovascular procedure. Mortality and neurological adverse event rate were compared between shunted CEA and cross-clamping intolerant cases converted into CAS. The secondary end-point was long-term survival. Carotid cross-clamp intolerance occurred in 30 cases (8.7%). CEA with Pruitt-Inahara's shunt was performed in 17 cases with a perioperative neurological adverse event rate of 23.5%. In 13 cases limitations to shunting due to quick onset of coma and/or an unfavorable anatomy were encountered. In these 13 cases the open intervention was immediately converted into endovascular procedure. Technical success was achieved in all the converted to CAS cases (100%), with a perioperative neurological adverse event rate of 7.7% (P=0.35 between the two groups). No significant difference emerges comparing patient's survival between the cases Nevertheless, the small dimension of this survey, immediate conversion to CAS resulted feasible with a lower risk of neurological adverse events if compared to CEA with shunt, and could be considered as an alternative to CEA when carotid shunt cannot be used safely.

  4. Production of microspheres labeled with holmium-166 for liver cancer therapy: the preliminary experience at IPEN/CNEN-SP

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Renata F.; Azevedo, Mariangela B.M.; Nascimento, Nanci; Sene, Frank F.; Martinelli, Jose R.; Osso Junior, Joao A., E-mail: renatafcosta@usp.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2009-07-01

    Microspheres labeled with therapeutic radionuclides for malignancies of liver are widely used in many countries. The internal radionuclide therapy uses a permanently implanted device, such as Therasphere{sup R} or SIR-Spheres{sup R}, or a biodegradable device that provides structural support for the radionuclide of choice and causes the tumor reduction. Three different types of material supports have been investigated, i.e., biodegradable polymer-based, glass-based and resin-based microspheres. Nowadays there is a project concerning the labeling of these 3 materials with {sup 166}Ho being developed at IPEN-CNEN/SP and coordinated by the Radiopharmacy Directory. {sup 166}Ho(t{sub 1/2}=26.8 h) is a beta minus emitter (E{sub max}=1.84 MeV), with right properties for radiotherapy and can be produced with the low power Brazilian Nuclear Reactor IEA-R1m. The aim of this work is to describe the stage of development of this project. The initial experience used resin-based microspheres, a cation exchange resin labeled with {sup 166}Ho, it showed the essential characteristics for liver therapy. Preliminary results of the preparation of glass-based microspheres labeled with {sup 165}Ho showed that 5% of Ho{sub 2}O{sub 3} was incorporated in an aluminosilicate glass, through the process of spheronization by flame, which produced spherical microspheres with 20-40mum particle size. The preparation of biodegradable material, polymer-based microspheres, is in its initial stage and the objective is to prepare and label with {sup 165}Ho different polymer-based microspheres. These combined efforts have been done to offer a national radiotherapeutic product for the the Brazilian nuclear medicine community at fair value and also to offer a viable possibility of treatment for patients affected by liver malignancies. (author)

  5. Mapped minerals at Questa, New Mexico, using airborne visible-infrared imaging spectrometer (AVIRIS) data -- Preliminary report

    Science.gov (United States)

    Livo, K. Eric; Clark, Roger N.

    2002-01-01

    This preliminary study for the First Quarterly Report has spectrally mapped hydrothermally altered minerals useful in assisting in assessment of water quality of the Red River. Airborne Visible-Infrared Imaging Spectrometer (AVIRIS) data was analyzed to characterize mined and unmined ground at Questa, New Mexico. AVIRIS data covers the Red River drainage north of the river, from between the town of Questa on the west, to east of the town of Red River. The data was calibrated and analyzed using U.S. Geological Survey custom software and spectral mineral library. AVIRIS data was tested for spectral features that matched similar features in the spectral mineral library. Goodness-of-fit and band-depth were calculated for each comparison of spectral features and used to identify surface mineralogy. Mineral distribution, mineral associations, and AVIRIS pixel spectra were examined. Mineral maps show the distribution of iron hydroxides, iron sulfates, clays, micas, carbonates, and other minerals. Initial results show a system of alteration suites that overprint each other. Quartz-sericite-pyrite (QSP) alteration grading out to propylitic alteration (epidote and calcite) was identified at the Questa Mine (molybdenum porphyry) and a similar alteration pattern was mapped at the landslide (?scar?) areas. Supergene weathering overprints the altered rock, as shown by jarosite, kaolinite, and gypsum. In the spectral analysis, hydrothermally altered ground appears to be more extensive at the unmined Goat Hill Gulch and the mined ground, than the ?scars? to the east. Though the ?scars? have similar overall altered mineral suites, there are differences between the ?scars? in sericite, kaolinite, jarosite, gypsum, and calcite abundance. Fieldwork has verified the results at the central unmined ?scar? areas.

  6. Ring imaging Cherenkov detector of PHENIX experiment at RHIC

    CERN Document Server

    Akiba, Y; Burward-Hoy, J; Chappell, R; Crook, D; Ebisu, K; Emery, M S; Ferriera, J; Frawley, A D; Hamagaki, H; Hara, H; Hayano, R S; Hemmick, T K; Hibino, M; Hutter, R; Kennedy, M; Kikuchi, J; Matsumoto, T; Moscone, C G; Nagasaka, Y; Nishimura, S; Oyama, K; Sakaguchi, T; Salomone, S; Shigaki, K; Tanaka, Y; Walker, J W; Wintenberg, A L; Young, G R

    1999-01-01

    The RICH detector of the PHENIX experiment at RHIC is currently under construction. Its main function is to identity electron tracks in a very high particle density, about 1000 charged particles per unit rapidity, expected in the most violent collisions at RHIC. The design and construction status of the detector and its expected performance are described.

  7. Image Schemas in Verb-Particle Constructions: Evidence from a Behavioral Experiment

    Science.gov (United States)

    Yang, Tangfeng

    2016-01-01

    Cognitive linguists claim that verb-particle constructions are compositional and analyzable, and that the particles contribute to the overall meaning in the form of image schemas. This article examined this claim with a behavioral experiment, in which participants were asked to judge the sensibility of short sentences primed by image-schematic…

  8. A qualitative exploration of body image experiences of women progressing through pregnancy.

    Science.gov (United States)

    Watson, Brittany; Broadbent, Jaclyn; Skouteris, Helen; Fuller-Tyszkiewicz, Matthew

    2016-02-01

    Pregnancy provides an interesting challenge to body image theories in that the natural physiological changes push women further from the socioculturally prescribed thin ideal which these theories hinge upon. The impact that these significant physiological changes have on the woman's body image during pregnancy may depend on the extent to which they retain or revise the ideal. However, little is known about body image experiences during pregnancy. To provide a comprehensive exploration of the body image experiences of pregnant women. Individual structured interviews were conducted with 19 currently pregnant women. Transcriptions were analysed using a thematic content analysis approach. Themes extracted from the qualitative data included: (1) women's body image experiences during pregnancy were complex and changing, and shaped by the salience of specific body parts, the women's expectations for future changes to their body within the perinatal period, the functionality of the body, and their experience of maternity clothing, (2) women were able to negotiate the changes to their bodies as they recognised the functionality of the pregnant body, (3) women were surprised by the public nature of the pregnant body, (4) partner support and positive feedback about the pregnant body was highly valued, and (5) the importance of open communication around weight and body image in antenatal healthcare. Our findings highlight the need for the adaptation and expansion of existing body image theories to be used as a framework for women's experiences of pregnancy. Crown Copyright © 2015. Published by Elsevier Ltd. All rights reserved.

  9. Beam test calibration of the balloon-borne imaging calorimeter for the CREAM experiment

    CERN Document Server

    Marrocchesi, P S; Bagliesi, M G; Basti, A; Bigongiari, G; Castellina, A; Ciocci, M A; Di Virgilio, A; Lomtatze, T; Ganel, O; Kim, K C; Lee, M H; Ligabue, F; Lutz, L; Maestro, P; Malinine, A; Meucci, M; Millucci, V; Morsani, F; Seo, E S; Sina, R; Wu, J; Wu, J; Yoon, Y S; Zei, R; Zinn, S Y

    2010-01-01

    CREAM (Cosmic Ray Energetics And Mass) is a multi-flight balloon mission designed to collect direct data on the elemental composition and individual energy spectra of cosmic rays. Two instrument suites have been built to be flown alternately on a yearly base. The tungsten/Sci-Fi imaging calorimeter for the second flight, scheduled for December 2005, was calibrated with electron and proton beams at CERN. A calibration procedure based on the study of the longitudinal shower profile is described and preliminary results of the beam test are presented.

  10. Experiments on terahertz 3D scanning microscopic imaging

    Science.gov (United States)

    Zhou, Yi; Li, Qi

    2016-10-01

    Compared with the visible light and infrared, terahertz (THz) radiation can penetrate nonpolar and nonmetallic materials. There are many studies on the THz coaxial transmission confocal microscopy currently. But few researches on the THz dual-axis reflective confocal microscopy were reported. In this paper, we utilized a dual-axis reflective confocal scanning microscope working at 2.52 THz. In contrast with the THz coaxial transmission confocal microscope, the microscope adopted in this paper can attain higher axial resolution at the expense of reduced lateral resolution, revealing more satisfying 3D imaging capability. Objects such as Chinese characters "Zhong-Hua" written in paper with a pencil and a combined sheet metal which has three layers were scanned. The experimental results indicate that the system can extract two Chinese characters "Zhong," "Hua" or three layers of the combined sheet metal. It can be predicted that the microscope can be applied to biology, medicine and other fields in the future due to its favorable 3D imaging capability.

  11. Ames Coronagraph Experiment: Enabling Missions to Directly Image Exoplanets

    Science.gov (United States)

    Belikov, Ruslan

    2014-01-01

    Technology to find biomarkers and life on other worlds is rapidly maturing. If there is a habitable planet around the nearest star, we may be able to detect it this decade with a small satellite mission. In the 2030 decade, we will likely know if there is life in our Galactic neighborhood (1000 nearest stars). The Ames Coronagraph Experiment is developing coronagraphic technologies to enable such missions.

  12. Cosmic AntiParticle Ring Imaging Cerenkov Experiment

    CERN Multimedia

    2002-01-01

    %RE2A \\\\ \\\\ %title \\\\ \\\\The CAPRICE experiment studies antimatter and light nuclei in the cosmic rays as well as muons in the atmosphere. The experiment is performed with the spectrometer shown in the figure which is lifted by a balloon to an altitude of 35-40 km. At this altitude less than half a percent of the atmosphere is above the 2 ton spectrometer which makes it possible to study the cosmic ray flux without too much background from atmospherically produced particles. The spectrometer includes time-of-flight scintillators, a gaseous RICH counter, a drift chamber tracker and a silicon electromagnetic calorimeter. The important feature of the spectrometer is to discriminate between different particles.\\\\ \\\\ The experiment aims at measuring the flux of the antiparticles (antiprotons and positrons) above about 5 GeV and relate the fluxes to models including exotic production of antiparticles like dark matter supersymmetric particles. The flux of muons is measured during descent of the balloon through the at...

  13. Body Image in a Sexual Context : The Relationship between Body Image and Sexual Experiences

    NARCIS (Netherlands)

    van den Brink, F.

    2017-01-01

    Given the large sociocultural emphasis on appearance and the widespread incidence of a negative body image in current society, scientific understanding of its potential psychological and physical health consequences, including sexual problems, is now of particular importance. The value of

  14. The analysis of frequency domain characteristics of emotional images in eye-tracking experiment

    Science.gov (United States)

    Fan, Boqiang; Ma, Huimin; Wang, Xiang

    2015-07-01

    Although recently eye-tracking method has been introduced into behavioral experiments based on dot-probe paradigm, some characteristics in eye-tracking data do not draw as much attention as traditional characteristics like reaction time. It is also necessary to associate eye-tracking data to characteristics of images shown in experiments. In this research, new variables, such as fixation length, times of fixation and times of eye movement, in eye-tracking data were extracted from a behavioral experiment based on dot probe paradigm. They were analyzed and compared to traditional reaction time. After the analysis of positive and negative scenery images, parameters such as hue frequency spectrum PAR (Peak to Average Ratio) were extracted and showed difference between negative and positive images. These parameters of emotional images could discriminate scenery images according to their emotions in an SVM classifier well. Besides, it was found that images' hue frequency spectrum PAR is obviously relevant to eye-tracking statistics. When the dot was on the negative side, negative images' hue frequency spectrum PAR and horizontal eye-jumps confirmed to hyperbolic distribution, while that of positive images was linear with horizontal eye-jumps. The result could help to explain the mechanism of human's attention and boost the study in computer vision.

  15. Clinical experiences of collaborative imaging diagnosis in Shanghai district healthcare services

    Science.gov (United States)

    Zhang, Kai; Ling, Tonghui; Yang, Yuanyuan; Sun, Jianyong; Wang, Mingqing; Zhang, Jianguo

    2016-03-01

    To improve healthcare service quality with balancing healthcare resources between large and small hospitals, as well as reducing costs, each district health administration in Shanghai with more than 24 million citizens has built image-enabled electronic healthcare records (iEHR) system to share patient medical records and encourage patients to visit small hospitals for initial evaluations and preliminary diagnoses first, then go to large hospitals to have better specialists' services. We implemented solution for iEHR systems, based on the IHE XDS-I integration profile and installed the systems in more than 100 hospitals cross three districts in Shanghai and one city in Jiangsu Province in last few years. Here, we give operational results of these systems in these four districts and evaluated the performance of the systems in servicing the regional collaborative imaging diagnosis.

  16. Preliminary results from multicenter clinical trials for detection of cervical squamous intraepithelial lesions using a novel full-field evoked-tissue-flourescence-based imaging instrument

    Science.gov (United States)

    Dattamajumdar, Anupam K.; Wells, D.; Parnell, Julie R.; Ganguly, Dipankur; Wright, Thomas C., Jr.

    2001-10-01

    We report preliminary results from a multi-center trial of evaluating the performance of a novel, full-field multi-spectral tissue fluorescence imaging system (CerviscanTM) designed to detect cervical squamous intraepithelial lesions. Spectral data from multiple regions of 48 patients enrolled from clinical performance sites in the US and Canada are included in this preliminary analysis. This includes 30 women used for the training set and 18 used for the testing set. In the testing set, 37/43 SIL and 70/80 NonSIL regions were correctly identified for a sensitivity of 86% and specificity of 87.5%. CerviscanTM locates cervical precancerous lesions with high sensitivity and specificity and has the potential to permit 'see and treat' patient management.

  17. The relationship study between image features and detection probability based on psychology experiments

    Science.gov (United States)

    Lin, Wei; Chen, Yu-hua; Wang, Ji-yuan; Gao, Hong-sheng; Wang, Ji-jun; Su, Rong-hua; Mao, Wei

    2011-04-01

    Detection probability is an important index to represent and estimate target viability, which provides basis for target recognition and decision-making. But it will expend a mass of time and manpower to obtain detection probability in reality. At the same time, due to the different interpretation of personnel practice knowledge and experience, a great difference will often exist in the datum obtained. By means of studying the relationship between image features and perception quantity based on psychology experiments, the probability model has been established, in which the process is as following.Firstly, four image features have been extracted and quantified, which affect directly detection. Four feature similarity degrees between target and background were defined. Secondly, the relationship between single image feature similarity degree and perception quantity was set up based on psychological principle, and psychological experiments of target interpretation were designed which includes about five hundred people for interpretation and two hundred images. In order to reduce image features correlativity, a lot of artificial synthesis images have been made which include images with single brightness feature difference, images with single chromaticity feature difference, images with single texture feature difference and images with single shape feature difference. By analyzing and fitting a mass of experiments datum, the model quantitys have been determined. Finally, by applying statistical decision theory and experimental results, the relationship between perception quantity with target detection probability has been found. With the verification of a great deal of target interpretation in practice, the target detection probability can be obtained by the model quickly and objectively.

  18. Multi-frequency harmonic arrays: initial experience with a novel transducer concept for nonlinear contrast imaging.

    Science.gov (United States)

    Forsberg, Flemming; Shi, William T; Jadidian, Bahram; Winder, Alan A

    2004-12-01

    Nonlinear contrast imaging modes such as second harmonic imaging (HI) and subharmonic imaging (SHI) are increasingly important for clinical applications. However, the performance of currently available transducers for HI and SHI is significantly constrained by their limited bandwidth. To bypass this constraint, a novel transducer concept termed multi-frequency harmonic transducer arrays (MFHA's) has been designed and a preliminary evaluation has been conducted. The MFHA may ultimately be used for broadband contrast enhanced HI and SHI with high dynamic range and consists of three multi-element piezo-composite sub-arrays (A-C) constructed so the center frequencies are 4f(A) = 2f(B) = f(C) (specifically 2.5/5.0/10.0 MHz and 1.75/3.5/7.0 MHz). In principle this enables SHI by transmitting on sub-array C receiving on B and, similarly, from B to A as well as HI by transmitting on A receiving on B and, likewise, from B to C. Initially transmit and receive pressure levels of the arrays were measured with the elements of each sub-array wired in parallel. Following contrast administration, preliminary in vitro HI and SHI signal-to-noise ratios of up to 40 dB were obtained. In conclusion, initial design and in vitro characterization of two MFHA's have been performed. They have an overall broad frequency bandwidth of at least two octaves. Due to the special design of the array assembly, the SNR for HI and SHI was comparable to that of regular B-mode and better than commercially available HI systems. However, further research on multi-element MFHA's is required before their potential for in vivo nonlinear contrast imaging can be assessed.

  19. Experience – Information – Image: A Historiography of Unfolding. Arab Cinema as Example

    Directory of Open Access Journals (Sweden)

    Laura U. Marks

    2011-04-01

    Full Text Available Why do certain images of history reach us, while others remain seemingly forgotten, in the infinite breadth of the past? Why do only certain events seem to matter? I suggest those experiences are not forgotten but enfolded. The contemporary politics of historiography can be conceptualized according to the relationship between Experience, Information, and Image; a triadic relationship I have proposed to understand the nature of the image in the information age. While Experience is infinite, the vast majority of experience lies latent. Few Images ever arise from it. In our age, those that do tend to be selected, or unfolded, by political and economic interests that deem them to be useful as Information. Nevertheless, anyone can unfold any aspect of Experience to become a public image, and artists (and others do so in order to allow other aspects of Experience to circulate, before they enfold, back into the matrix of history. I will show an animated diagram that illustrates this concept of history as a flow of unfolding and enfolding, influenced by concepts from Charles Sanders Peirce and Gilles Deleuze.   Many artworks can be illuminated by this process. My examples will be drawn from contemporary Arab cinema. In the heavily politicized Arab milieu, the Image world is constructed as a selective unfolding of only those aspects of Experience that are deemed to be useful or profitable. Some Arab filmmakers, rather than deconstruct the resulting ideological images, prefer to carry out their own unfoldings:  explicating hitherto latent events, knowledges, and sensations. Thus what official history deems merely personal, absurd, micro-events, or no events at all, becomes the stuff of a rich alternative historiography. This process characterizes the work of, among others, Joana Hadjithomas and Khalil Joreige, Nisrine Khodr, Mohammed Soueid, and Akram Zaatari (Lebanon, Azza El-Hassan, Elia Suleiman, and Sobhi Al-Zobaidi (Palestine, and Mohamad Khan

  20. μSPECT: image evaluation using collimator type pinhole. Preliminary results; μSPECT: avaliacao da imagem utilizando colimador tipo pinhole: resultados preliminares

    Energy Technology Data Exchange (ETDEWEB)

    Miady, Leandro Sunao [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Sao Jose do Rio Preto, SP (Brazil); Squair, Peterson Lima [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil); Pozzo, Lorena, E-mail: lorena.pozzo@ipen.br [Universidade de Sao Paulo (USP), SP (Brazil)

    2015-04-15

    At scintigraphy, the method of obtaining tomographic image is called SPECT (single photon emission computed tomography), as well as the equipment able to acquire such tomographic images involving small animals can be called μSPECT. Although the equipment is directed to the acquisition of three-dimensional images, a need exists in certain studies to obtain two-dimensional images. This study aims to verify and analyze the two-dimensional image magnification factor for later application to the study of {sup 131}I dosimetry in mice. The experimental results allowed to analyze and compare the magnification factors for each parameter used for future experiments. (author)

  1. Body Image in a Sexual Context : The Relationship between Body Image and Sexual Experiences

    NARCIS (Netherlands)

    van den Brink, F.

    2017-01-01

    Given the large sociocultural emphasis on appearance and the widespread incidence of a negative body image in current society, scientific understanding of its potential psychological and physical health consequences, including sexual problems, is now of particular importance. The value of understand

  2. Articular cartilage surface roughness as an imaging-based morphological indicator of osteoarthritis: A preliminary investigation of osteoarthritis initiative subjects.

    Science.gov (United States)

    Newton, Michael D; Osborne, Jeffrey; Gawronski, Karissa; Baker, Kevin C; Maerz, Tristan

    2017-04-29

    Current imaging-based morphometric indicators of osteoarthritis (OA) using whole-compartment mean cartilage thickness (MCT) and volume changes can be insensitive to mild degenerative changes of articular cartilage (AC) due to areas of adjacent thickening and thinning. The purpose of this preliminary study was to evaluate cartilage thickness-based surface roughness as a morphometric indicator of OA. 3D magnetic resonance imaging (MRI) datasets were collected from osteoarthritis initiative (OAI) s