WorldWideScience

Sample records for preliminary global analysis

  1. Global volcanic earthquake swarm database and preliminary analysis of volcanic earthquake swarm duration

    Directory of Open Access Journals (Sweden)

    S. R. McNutt

    1996-06-01

    Full Text Available Global data from 1979 to 1989 pertaining to volcanic earthquake swarms have been compiled into a custom-designed relational database. The database is composed of three sections: 1 a section containing general information on volcanoes, 2 a section containing earthquake swarm data (such as dates of swarm occurrence and durations, and 3 a section containing eruption information. The most abundant and reliable parameter, duration of volcanic earthquake swarms, was chosen for preliminary analysis. The distribution of all swarm durations was found to have a geometric mean of 5.5 days. Precursory swarms were then separated from those not associated with eruptions. The geometric mean precursory swarm duration was 8 days whereas the geometric mean duration of swarms not associated with eruptive activity was 3.5 days. Two groups of precursory swarms are apparent when duration is compared with the eruption repose time. Swarms with durations shorter than 4 months showed no clear relationship with the eruption repose time. However, the second group, lasting longer than 4 months, showed a significant positive correlation with the log10 of the eruption repose period. The two groups suggest that different suites of physical processes are involved in the generation of volcanic earthquake swarms.

  2. Preliminary Analysis on the Global Features of the NCEP CFSv2 Seasonal Hindcasts

    Directory of Open Access Journals (Sweden)

    Gyrlene A. M. Silva

    2014-01-01

    Full Text Available The representation of the CFSv2 ocean-atmosphere ensemble hindcasts is investigated during Dec-Jan-Feb (DJF and Jun-Jul-Aug (JJA from 1983 to 2010. The skill anomaly correlations showed that in some continents the forecasts do not have dependency with changes in the initial conditions. Also, in both seasons the model has a higher skill at the 0-month lead time with the largest spatial biases occurring over the North America, South America, and Oceania. Over the continents the largest biases in the nonlinearity of El Niño minus La Niña events are found over the eastern South Africa, part of Oceania, and central-southeastern parts of South America. During DJF the main biases are related to double-ITCZ, strengthening of SPCZ, and deepening of the Aleutian and Icelandic low pressures. The simulation of a warmer SST on the eastern of most austral oceans, the strengthening (weakening of the Subtropical (Polar Jet over the Southern Hemisphere, and the weakening of the zonal circulation near the Antarctic continent are also found in both seasons. Over the central-eastern Equatorial Pacific a cooler bias in SST is found during JJA. These biases are interpreted by analyses of the simulated global mean-state and their impact on the main patterns of variability.

  3. Inference of Global HIV-1 Sequence Patterns and Preliminary Feature Analysis

    Institute of Scientific and Technical Information of China (English)

    Yan Wang; Reda Rawi; Daniel Hoffmann; Binlian Sun; Rongge Yang

    2013-01-01

    The epidemiology of HIV-1 varies in different areas of the world,and it is possible that this complexity may leave unique footprints in the viral genome.Thus,we attempted to find significant patterns in global HIV-1 genome sequences.By applying the rule inference algorithm RIPPER (Repeated Incremental Pruning to Produce Error Reduction) to multiple sequence alignments of Env sequences from four classes of compiled datasets,we generated four sets of signature patterns.We found that these patterns were able to distinguish southeastern Asian from nonsoutheastern Asian sequences with 97.5% accuracy,Chinese from non-Chinese sequences with 98.3% accuracy,African from non-African sequences with 88.4% accuracy,and southern African from non-southern African sequences with 91.2% accuracy.These patterns showed different associations with subtypes and with amino acid positions.In addition,some signature patterns were characteristic of the geographic area from which the sample was taken.Amino acid features corresponding to the phylogenetic clustering of HIV-1 sequences were consistent with some of the deduced patterns.Using a combination of patterns inferred from subtypes B,C,and all subtypes chimeric with CRF01_AE worldwide,we found that signature patterns of subtype C were extremely common in some sampled countries (for example,Zambia in southern Africa),which may hint at the origin of this HIV-1 subtype and the need to pay special attention to this area of Africa.Signature patterns of subtype B sequences were associated with different countries.Even more,there are distinct patterns at single position 21 with glycine,leucine and isoleucine corresponding to subtype C,B and all possible recombination forms chimeric with CRF01_AE,which also indicate distinct geographic features.Our method widens the scope of inference of signature from geographic,genetic,and genomic viewpoints.These findings may provide a valuable reference for epidemiological research or vaccine design.

  4. Preliminary Analysis of Low-Thrust Gravity Assist Trajectories by An Inverse Method and a Global Optimization Technique.

    Science.gov (United States)

    de Pascale, P.; Vasile, M.; Casotto, S.

    The design of interplanetary trajectories requires the solution of an optimization problem, which has been traditionally solved by resorting to various local optimization techniques. All such approaches, apart from the specific method employed (direct or indirect), require an initial guess, which deeply influences the convergence to the optimal solution. The recent developments in low-thrust propulsion have widened the perspectives of exploration of the Solar System, while they have at the same time increased the difficulty related to the trajectory design process. Continuous thrust transfers, typically characterized by multiple spiraling arcs, have a broad number of design parameters and thanks to the flexibility offered by such engines, they typically turn out to be characterized by a multi-modal domain, with a consequent larger number of optimal solutions. Thus the definition of the first guesses is even more challenging, particularly for a broad search over the design parameters, and it requires an extensive investigation of the domain in order to locate the largest number of optimal candidate solutions and possibly the global optimal one. In this paper a tool for the preliminary definition of interplanetary transfers with coast-thrust arcs and multiple swing-bys is presented. Such goal is achieved combining a novel methodology for the description of low-thrust arcs, with a global optimization algorithm based on a hybridization of an evolutionary step and a deterministic step. Low thrust arcs are described in a 3D model in order to account the beneficial effects of low-thrust propulsion for a change of inclination, resorting to a new methodology based on an inverse method. The two-point boundary values problem (TPBVP) associated with a thrust arc is solved by imposing a proper parameterized evolution of the orbital parameters, by which, the acceleration required to follow the given trajectory with respect to the constraints set is obtained simply through

  5. Analysis of the global free infra-gravity wave climate for the SWOT mission, and preliminary results of numerical modelling

    Science.gov (United States)

    Rawat, A.; Aucan, J.; Ardhuin, F.

    2012-12-01

    All sea level variations of the order of 1 cm at scales under 30 km are of great interest for the future Surface Water Ocean Topography (SWOT) satellite mission. That satellite should provide high-resolution maps of the sea surface height for analysis of meso to sub-mesoscale currents, but that will require a filtering of all gravity wave motions in the data. Free infragravity waves (FIGWs) are generated and radiate offshore when swells and/or wind seas and their associated bound infragravity waves impact exposed coastlines. Free infragravity waves have dominant periods comprised between 1 and 10 minutes and horizontal wavelengths of up to tens of kilometers. Given the length scales of the infragravity waves wavelength and amplitude, the infragravity wave field will can a significant fraction the signal measured by the future SWOT mission. In this study, we analyze the data from recovered bottom pressure recorders of the Deep-ocean Assessment and Reporting of Tsunami (DART) program. This analysis includes data spanning several years between 2006 and 2010, from stations at different latitudes in the North and South Pacific, the North Atlantic, the Gulf of Mexico and the Caribbean Sea. We present and discuss the following conclusions: (1) The amplitude of free infragravity waves can reach several centimeters, higher than the precision sought for the SWOT mission. (2) The free infragravity signal is higher in the Eastern North Pacific than in the Western North Pacific, possibly due to smaller incident swell and seas impacting the nearby coastlines. (3) Free infragravity waves are higher in the North Pacific than in the North Atlantic, possibly owing to different average continental shelves configurations in the two basins. (4) There is a clear seasonal cycle at the high latitudes North Atlantic and Pacific stations that is much less pronounced or absent at the tropical stations, consistent with the generation mechanism of free infragravity waves. Our numerical model

  6. A computerized global MR image feature analysis scheme to assist diagnosis of breast cancer: a preliminary assessment

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Qian [College of Life Information Science and Instrument Engineering, Hangzhou Dianzi University, Hangzhou, 310018 (China); Li, Lihua, E-mail: lilh@hdu.edu.cn [College of Life Information Science and Instrument Engineering, Hangzhou Dianzi University, Hangzhou, 310018 (China); Zhang, Juan; Shao, Guoliang [Zhejiang Cancer Hospital, Hangzhou, 310010 (China); Zheng, Bin [College of Life Information Science and Instrument Engineering, Hangzhou Dianzi University, Hangzhou, 310018 (China); School of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019 (United States)

    2014-07-15

    Objectives: To develop a new computer-aided detection scheme to compute a global kinetic image feature from the dynamic contrast enhanced breast magnetic resonance imaging (DCE-MRI) and test the feasibility of using the computerized results for assisting classification between the DCE-MRI examinations associated with malignant and benign tumors. Materials and Methods: The scheme registers sequential images acquired from each DCE-MRI examination, segments breast areas on all images, searches for a fraction of voxels that have higher contrast enhancement values and computes an average contrast enhancement value of selected voxels. Combination of the maximum contrast enhancement values computed from two post-contrast series in one of two breasts is applied to predict the likelihood of the examination being positive for breast cancer. The scheme performance was evaluated when applying to a retrospectively collected database including 80 malignant and 50 benign cases. Results: In each of 91% of malignant cases and 66% of benign cases, the average contrast enhancement value computed from the top 0.43% of voxels is higher in the breast depicted suspicious lesions as compared to another negative (lesion-free) breast. In classifying between malignant and benign cases, using the computed image feature achieved an area under a receiver operating characteristic curve of 0.839 with 95% confidence interval of [0.762, 0.898]. Conclusions: We demonstrated that the global contrast enhancement feature of DCE-MRI can be relatively easily and robustly computed without accurate breast tumor detection and segmentation. This global feature provides supplementary information and a higher discriminatory power in assisting diagnosis of breast cancer.

  7. UVISS preliminary visibility analysis

    DEFF Research Database (Denmark)

    Betto, Maurizio

    1998-01-01

    The goal of this work is to obtain a preliminary assessment of the sky visibility for anastronomical telescope located on the express pallet of the International SpaceStation (ISS)} taking into account the major constraints imposed on the instrument by the ISSattitude and structure. Part of the w......The goal of this work is to obtain a preliminary assessment of the sky visibility for anastronomical telescope located on the express pallet of the International SpaceStation (ISS)} taking into account the major constraints imposed on the instrument by the ISSattitude and structure. Part...

  8. UVISS preliminary visibility analysis

    DEFF Research Database (Denmark)

    Betto, Maurizio

    1998-01-01

    The goal of this work is to obtain a preliminary assessment of the sky visibility for anastronomical telescope located on the express pallet of the International SpaceStation (ISS)} taking into account the major constraints imposed on the instrument by the ISSattitude and structure. Part...

  9. Concept Overview & Preliminary Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ruth, Mark

    2017-07-12

    'H2@Scale' is an opportunity for wide-scale use of hydrogen as an intermediate that carries energy from various production options to multiple uses. It is based on identifying and developing opportunities for low-cost hydrogen production and investigating opportunities for using that hydrogen across the electricity, industrial, and transportation sectors. One of the key production opportunities is use of low-cost electricity that may be generated under high penetrations of variable renewable generators such as wind and solar photovoltaics. The technical potential demand for hydrogen across the sectors is 60 million metric tons per year. The U.S. has sufficient domestic renewable resources so that each could meet that demand and could readily meet the demand using a portfolio of generation options. This presentation provides an overview of the concept and the technical potential demand and resources. It also motivates analysis and research on H2@Scale.

  10. Preliminary evaluation of diabatic heating distribution from FGGE level 3b analysis data

    Science.gov (United States)

    Kasahara, A.; Mizzi, A. P.

    1985-01-01

    A method is presented for calculating the global distribution of diabatic heating rate. Preliminary results of global heating rate evaluated from the European center for Medium Range Weather Forecasts Level IIIb analysis data is also presented.

  11. Preliminary hazards analysis -- vitrification process

    Energy Technology Data Exchange (ETDEWEB)

    Coordes, D.; Ruggieri, M.; Russell, J.; TenBrook, W.; Yimbo, P. [Science Applications International Corp., Pleasanton, CA (United States)

    1994-06-01

    This paper presents a Preliminary Hazards Analysis (PHA) for mixed waste vitrification by joule heating. The purpose of performing a PHA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PHA is then followed by a Preliminary Safety Analysis Report (PSAR) performed during Title 1 and 2 design. The PSAR then leads to performance of the Final Safety Analysis Report performed during the facility`s construction and testing. It should be completed before routine operation of the facility commences. This PHA addresses the first four chapters of the safety analysis process, in accordance with the requirements of DOE Safety Guidelines in SG 830.110. The hazards associated with vitrification processes are evaluated using standard safety analysis methods which include: identification of credible potential hazardous energy sources; identification of preventative features of the facility or system; identification of mitigative features; and analyses of credible hazards. Maximal facility inventories of radioactive and hazardous materials are postulated to evaluate worst case accident consequences. These inventories were based on DOE-STD-1027-92 guidance and the surrogate waste streams defined by Mayberry, et al. Radiological assessments indicate that a facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous materials assessment indicates that a Mixed Waste Vitrification facility will be a Low Hazard facility having minimal impacts to offsite personnel and the environment.

  12. Analysis of Multiple Precipitation Products and Preliminary Assessment of Their Impact on Global Land Data Assimilation System (GLDAS) Land Surface States

    Science.gov (United States)

    Gottschalck, Jon; Meng, Jesse; Rodel, Matt; Houser, paul

    2005-01-01

    Land surface models (LSMs) are computer programs, similar to weather and climate prediction models, which simulate the stocks and fluxes of water (including soil moisture, snow, evaporation, and runoff) and energy (including the temperature of and sensible heat released from the soil) after they arrive on the land surface as precipitation and sunlight. It is not currently possible to measure all of the variables of interest everywhere on Earth with sufficient accuracy and space-time resolution. Hence LSMs have been developed to integrate the available observations with our understanding of the physical processes involved, using powerful computers, in order to map these stocks and fluxes as they change in time. The maps are used to improve weather forecasts, support water resources and agricultural applications, and study the Earth's water cycle and climate variability. NASA's Global Land Data Assimilation System (GLDAS) project facilitates testing of several different LSMs with a variety of input datasets (e.g., precipitation, plant type). Precipitation is arguably the most important input to LSMs. Many precipitation datasets have been produced using satellite and rain gauge observations and weather forecast models. In this study, seven different global precipitation datasets were evaluated over the United States, where dense rain gauge networks contribute to reliable precipitation maps. We then used the seven datasets as inputs to GLDAS simulations, so that we could diagnose their impacts on output stocks and fluxes of water. In terms of totals, the Climate Prediction Center (CPC) Merged Analysis of Precipitation (CMAP) had the closest agreement with the US rain gauge dataset for all seasons except winter. The CMAP precipitation was also the most closely correlated in time with the rain gauge data during spring, fall, and winter, while the satellitebased estimates performed best in summer. The GLDAS simulations revealed that modeled soil moisture is highly

  13. Hydrothermal Liquefaction Treatment Preliminary Hazard Analysis Report

    Energy Technology Data Exchange (ETDEWEB)

    Lowry, Peter P.; Wagner, Katie A.

    2015-08-31

    A preliminary hazard assessment was completed during February 2015 to evaluate the conceptual design of the modular hydrothermal liquefaction treatment system. The hazard assessment was performed in 2 stages. An initial assessment utilizing Hazard Identification and Preliminary Hazards Analysis (PHA) techniques identified areas with significant or unique hazards (process safety-related hazards) that fall outside of the normal operating envelope of PNNL and warranted additional analysis. The subsequent assessment was based on a qualitative What-If analysis. This analysis was augmented, as necessary, by additional quantitative analysis for scenarios involving a release of hazardous material or energy with the potential for affecting the public.

  14. Global Analysis of Nonlinear Dynamics

    CERN Document Server

    Luo, Albert

    2012-01-01

    Global Analysis of Nonlinear Dynamics collects chapters on recent developments in global analysis of non-linear dynamical systems with a particular emphasis on cell mapping methods developed by Professor C.S. Hsu of the University of California, Berkeley. This collection of contributions prepared by a diverse group of internationally recognized researchers is intended to stimulate interests in global analysis of complex and high-dimensional nonlinear dynamical systems, whose global properties are largely unexplored at this time. This book also: Presents recent developments in global analysis of non-linear dynamical systems Provides in-depth considerations and extensions of cell mapping methods Adopts an inclusive style accessible to non-specialists and graduate students Global Analysis of Nonlinear Dynamics is an ideal reference for the community of nonlinear dynamics in different disciplines including engineering, applied mathematics, meteorology, life science, computational science, and medicine.  

  15. Global Assessment of Hydrogen Technologies – Tasks 3 & 4 Report Economic, Energy, and Environmental Analysis of Hydrogen Production and Delivery Options in Select Alabama Markets: Preliminary Case Studies

    Energy Technology Data Exchange (ETDEWEB)

    Fouad, Fouad H.; Peters, Robert W.; Sisiopiku, Virginia P.; Sullivan Andrew J.; Gillette, Jerry; Elgowainy, Amgad; Mintz, Marianne

    2007-12-01

    This report documents a set of case studies developed to estimate the cost of producing, storing, delivering, and dispensing hydrogen for light-duty vehicles for several scenarios involving metropolitan areas in Alabama. While the majority of the scenarios focused on centralized hydrogen production and pipeline delivery, alternative delivery modes were also examined. Although Alabama was used as the case study for this analysis, the results provide insights into the unique requirements for deploying hydrogen infrastructure in smaller urban and rural environments that lie outside the DOE’s high priority hydrogen deployment regions. Hydrogen production costs were estimated for three technologies – steam-methane reforming (SMR), coal gasification, and thermochemical water-splitting using advanced nuclear reactors. In all cases examined, SMR has the lowest production cost for the demands associated with metropolitan areas in Alabama. Although other production options may be less costly for larger hydrogen markets, these were not examined within the context of the case studies.

  16. Preliminary safety analysis methodology for the SMART

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Kyoo Hwan; Chung, Y. J.; Kim, H. C.; Sim, S. K.; Lee, W. J.; Chung, B. D.; Song, J. H. [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2000-03-01

    This technical report was prepared for a preliminary safety analysis methodology of the 330MWt SMART (System-integrated Modular Advanced ReacTor) which has been developed by Korea Atomic Energy Research Institute (KAERI) and funded by the Ministry of Science and Technology (MOST) since July 1996. This preliminary safety analysis methodology has been used to identify an envelope for the safety of the SMART conceptual design. As the SMART design evolves, further validated final safety analysis methodology will be developed. Current licensing safety analysis methodology of the Westinghouse and KSNPP PWRs operating and under development in Korea as well as the Russian licensing safety analysis methodology for the integral reactors have been reviewed and compared to develop the preliminary SMART safety analysis methodology. SMART design characteristics and safety systems have been reviewed against licensing practices of the PWRs operating or KNGR (Korean Next Generation Reactor) under construction in Korea. Detailed safety analysis methodology has been developed for the potential SMART limiting events of main steam line break, main feedwater pipe break, loss of reactor coolant flow, CEA withdrawal, primary to secondary pipe break and the small break loss of coolant accident. SMART preliminary safety analysis methodology will be further developed and validated in parallel with the safety analysis codes as the SMART design further evolves. Validated safety analysis methodology will be submitted to MOST as a Topical Report for a review of the SMART licensing safety analysis methodology. Thus, it is recommended for the nuclear regulatory authority to establish regulatory guides and criteria for the integral reactor. 22 refs., 18 figs., 16 tabs. (Author)

  17. Twelve metropolitan carbon footprints: A preliminary comparative global assessment

    Energy Technology Data Exchange (ETDEWEB)

    Sovacool, Benjamin K., E-mail: bsovacool@nus.edu.s [Lee Kuan Yew School of Public Policy, National University of Singapore (Singapore); Brown, Marilyn A., E-mail: Marilyn.Brown@pubpolicy.gatech.ed [School of Public Policy, Georgia Institute of Technology, Atlanta, Georgia (United States)

    2010-09-15

    A dearth of available data on carbon emissions and comparative analysis between metropolitan areas make it difficult to confirm or refute best practices and policies. To help provide benchmarks and expand our understanding of urban centers and climate change, this article offers a preliminary comparison of the carbon footprints of 12 metropolitan areas. It does this by examining emissions related to vehicles, energy used in buildings, industry, agriculture, and waste. The carbon emissions from these sources-discussed here as the metro area's partial carbon footprint-provide a foundation for identifying the pricing, land use, help metropolitan areas throughout the world respond to climate change. The article begins by exploring a sample of the existing literature on urban morphology and climate change and explaining the methodology used to calculate each area's carbon footprint. The article then depicts the specific carbon footprints for Beijing, Jakarta, London, Los Angeles, Manila, Mexico City, New Delhi, New York, Sao Paulo, Seoul, Singapore, and Tokyo and compares these to respective national averages. It concludes by offering suggestions for how city planners and policymakers can reduce the carbon footprint of these and possibly other large urban areas.

  18. Twelve metropolitan carbon footprints. A preliminary comparative global assessment

    Energy Technology Data Exchange (ETDEWEB)

    Sovacool, Benjamin K. [Lee Kuan Yew School of Public Policy, National University of Singapore (Singapore); Brown, Marilyn A. [School of Public Policy, Georgia Institute of Technology, Atlanta, Georgia (United States)

    2010-09-15

    A dearth of available data on carbon emissions and comparative analysis between metropolitan areas make it difficult to confirm or refute best practices and policies. To help provide benchmarks and expand our understanding of urban centers and climate change, this article offers a preliminary comparison of the carbon footprints of 12 metropolitan areas. It does this by examining emissions related to vehicles, energy used in buildings, industry, agriculture, and waste. The carbon emissions from these sources - discussed here as the metro area's partial carbon footprint - provide a foundation for identifying the pricing, land use, help metropolitan areas throughout the world respond to climate change. The article begins by exploring a sample of the existing literature on urban morphology and climate change and explaining the methodology used to calculate each area's carbon footprint. The article then depicts the specific carbon footprints for Beijing, Jakarta, London, Los Angeles, Manila, Mexico City, New Delhi, New York, Sao Paulo, Seoul, Singapore, and Tokyo and compares these to respective national averages. It concludes by offering suggestions for how city planners and policymakers can reduce the carbon footprint of these and possibly other large urban areas. (author)

  19. Introduction to global analysis

    CERN Document Server

    Kahn, Donald W

    2007-01-01

    This text introduces the methods of mathematical analysis as applied to manifolds, including the roles of differentiation and integration, infinite dimensions, Morse theory, Lie groups, and dynamical systems. 1980 edition.

  20. Preliminary Analysis of Google+'s Privacy

    OpenAIRE

    2011-01-01

    In this paper we provide a preliminary analysis of Google+ privacy. We identified that Google+ shares photo metadata with users who can access the photograph and discuss its potential impact on privacy. We also identified that Google+ encourages the provision of other names including maiden name, which may help criminals performing identity theft. We show that Facebook lists are a superset of Google+ circles, both functionally and logically, even though Google+ provides a better user interfac...

  1. Global analysis studies and applications

    CERN Document Server

    Gliklikh, Yuri; Vershik, A

    1992-01-01

    This volume (a sequel to LNM 1108, 1214, 1334 and 1453) continues the presentation to English speaking readers of the Voronezh University press series on Global Analysis and Its Applications. The papers are selected fromtwo Russian issues entitled "Algebraic questions of Analysis and Topology" and "Nonlinear Operators in Global Analysis". CONTENTS: YuE. Gliklikh: Stochastic analysis, groups of diffeomorphisms and Lagrangian description of viscous incompressible fluid.- A.Ya. Helemskii: From topological homology: algebras with different properties of homological triviality.- V.V. Lychagin, L.V. Zil'bergleit: Duality in stable Spencer cohomologies.- O.R. Musin: On some problems of computational geometry and topology.- V.E. Nazaikinskii, B.Yu. Sternin, V.E.Shatalov: Introduction to Maslov's operational method (non-commutative analysis and differential equations).- Yu.B. Rudyak: The problem of realization of homology classes from Poincare up to the present.- V.G. Zvyagin, N.M. Ratiner: Oriented degree of Fredholm...

  2. Convex analysis and global optimization

    CERN Document Server

    Tuy, Hoang

    2016-01-01

    This book presents state-of-the-art results and methodologies in modern global optimization, and has been a staple reference for researchers, engineers, advanced students (also in applied mathematics), and practitioners in various fields of engineering. The second edition has been brought up to date and continues to develop a coherent and rigorous theory of deterministic global optimization, highlighting the essential role of convex analysis. The text has been revised and expanded to meet the needs of research, education, and applications for many years to come. Updates for this new edition include: · Discussion of modern approaches to minimax, fixed point, and equilibrium theorems, and to nonconvex optimization; · Increased focus on dealing more efficiently with ill-posed problems of global optimization, particularly those with hard constraints;

  3. Preliminary Hazards Analysis Plasma Hearth Process

    Energy Technology Data Exchange (ETDEWEB)

    Aycock, M.; Coordes, D.; Russell, J.; TenBrook, W.; Yimbo, P. [Science Applications International Corp., Pleasanton, CA (United States)

    1993-11-01

    This Preliminary Hazards Analysis (PHA) for the Plasma Hearth Process (PHP) follows the requirements of United States Department of Energy (DOE) Order 5480.23 (DOE, 1992a), DOE Order 5480.21 (DOE, 1991d), DOE Order 5480.22 (DOE, 1992c), DOE Order 5481.1B (DOE, 1986), and the guidance provided in DOE Standards DOE-STD-1027-92 (DOE, 1992b). Consideration is given to ft proposed regulations published as 10 CFR 830 (DOE, 1993) and DOE Safety Guide SG 830.110 (DOE, 1992b). The purpose of performing a PRA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PRA then is followed by a Preliminary Safety Analysis Report (PSAR) performed during Title I and II design. This PSAR then leads to performance of the Final Safety Analysis Report performed during construction, testing, and acceptance and completed before routine operation. Radiological assessments indicate that a PHP facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous material assessments indicate that a PHP facility will be a Low Hazard facility having no significant impacts either onsite or offsite to personnel and the environment.

  4. Preliminary results of the global forest biomass survey

    Science.gov (United States)

    S. Healey; E. Lindquist

    2014-01-01

    Many countries do not yet have well-established national forest inventories, and among those that do, significant methodological differences exist, particularly in the estimation of standing forest biomass. Global space-based LiDAR (Light Detection and Ranging) from NASA’s now-completed ICESat mission provided consistent, high-quality measures of canopy height and...

  5. Preliminary results and analyses of using IGS GPS data to determine global ionospheric TEC

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Using the spherical harmonic (SH) function model and the dual frequency GPS data of 139 International GPS Service (IGS) stations for July 15 of 2000, the global ionospheric total electron content (TEC) is calculated and the basic method is investigated. Here, preliminary results are reported and the problems and difficulties to be solved for using GPS data to determine the global ionospheric TEC are discussed.

  6. Global Analysis of Neutrino Oscillation

    CERN Document Server

    Goswami, S; Choubey, S; Goswami, Srubabati; Bandyopadhyay, Abhijit; Choubey, Sandhya

    2005-01-01

    We present the constraints on neutrino oscillation parameters $\\Delta m^2_{\\odot}$ and $\\theta_{\\odot}$ governing the solar neutrino oscillations from two generation analysis of solar and KamLAND data. We include the latest 766.3 ton year KamLAND data in our analysis. We also present the allowed values of parameters $\\Delta m^2_{atm}$ and $\\sin^2\\theta_{atm}$ from two generation oscillation analysis of SuperKamiokande atmospheric and K2K data. For both cases we discuss the precision achieved in the present set of experiments and also how the precision can be improved in future. We also obtain the bounds on $\\theta_{13}$ from three generation analysis of global oscillation data. We emphasise on the roles played by different data sets in constraining the allowed parameter ranges.

  7. Global Analysis of Neutrino Oscillation

    Energy Technology Data Exchange (ETDEWEB)

    Goswami, Srubabati [Harish-Chandra Research Institute, Chhatnag Road, Jhusi, Allahabad 211 019 (India); Bandyopadhyay, Abhijit [Theory Group, Saha Institute of Nuclear Physics, 1/AF, Bidhannagar, Calcutta 700 064 (India); Choubey, Sandhya [INFN, Sezione di Trieste and Scuola Internazionale Superiore di Studi Avanzati, I-34014, Trieste (Italy)

    2005-06-15

    We present the constraints on neutrino oscillation parameters {delta}m{sub -}bar {sup 2} and {theta}{sub -}bar governing the solar neutrino oscillations from two generation analysis of solar and KamLAND data. We include the latest 766.3 ton year KamLAND data in our analysis. We also present the allowed values of parameters {delta}m{sub atm}{sup 2} and sin{sup 2}{theta}{sub atm} from two generation oscillation analysis of SuperKamiokande atmospheric and K2K data. For both cases we discuss the precision achieved in the present set of experiments and also how the precision can be improved in future. We also obtain the bounds on {theta}{sub 13} from three generation analysis of global oscillation data. We emphasise on the roles played by different data sets in constraining the allowed parameter ranges.

  8. Repository Subsurface Preliminary Fire Hazard Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Richard C. Logan

    2001-07-30

    This fire hazard analysis identifies preliminary design and operations features, fire, and explosion hazards, and provides a reasonable basis to establish the design requirements of fire protection systems during development and emplacement phases of the subsurface repository. This document follows the Technical Work Plan (TWP) (CRWMS M&O 2001c) which was prepared in accordance with AP-2.21Q, ''Quality Determinations and Planning for Scientific, Engineering, and Regulatory Compliance Activities''; Attachment 4 of AP-ESH-008, ''Hazards Analysis System''; and AP-3.11Q, ''Technical Reports''. The objective of this report is to establish the requirements that provide for facility nuclear safety and a proper level of personnel safety and property protection from the effects of fire and the adverse effects of fire-extinguishing agents.

  9. Preliminary Analysis of a Novel SAR Based Emergency System for Earth Orbit Satellites using Galileo

    NARCIS (Netherlands)

    Gill, E.K.A.; Helderweirt, A.

    2010-01-01

    This paper presents a preliminary analysis of a novel Search and Rescue (SAR) based emergency system for Low Earth Orbit (LEO) satellites using the Galileo Global Navigation Satellite System (GNSS). It starts with a description of the space user SAR system including a concept description, mission ar

  10. BASE Flexible Array Preliminary Lithospheric Structure Analysis

    Science.gov (United States)

    Yeck, W. L.; Sheehan, A. F.; Anderson, M. L.; Siddoway, C. S.; Erslev, E.; Harder, S. H.; Miller, K. C.

    2009-12-01

    The Bighorns Arch Seismic Experiment (BASE) is a Flexible Array experiment integrated with EarthScope. The goal of BASE is to develop a better understanding of how basement-involved foreland arches form and what their link is to plate tectonic processes. To achieve this goal, the crustal structure under the Bighorn Mountain range, Bighorn Basin, and Powder River Basin of northern Wyoming and southern Montana are investigated through the deployment of 35 broadband seismometers, 200 short period seismometers, 1600 “Texan” instruments using active sources and 800 “Texan” instruments monitoring passive sources, together with field structural analysis of brittle structures. The novel combination of these approaches and anticipated simultaneous data inversion will give a detailed structural crustal image of the Bighorn region at all levels of the crust. Four models have been proposed for the formation of the Bighorn foreland arch: subhorizontal detachment within the crust, lithospheric buckling, pure shear lithospheric thickening, and fault blocks defined by lithosphere-penetrating thrust faults. During the summer of 2009, we deployed 35 broadband instruments, which have already recorded several magnitude 7+ teleseismic events. Through P wave receiver function analysis of these 35 stations folded in with many EarthScope Transportable Array stations in the region, we present a preliminary map of the Mohorovicic discontinuity. This crustal map is our first test of how the unique Moho geometries predicted by the four hypothesized models of basement involved arches fit seismic observations for the Bighorn Mountains. In addition, shear-wave splitting analysis for our first few recorded teleseisms helps us determine if strong lithospheric deformation is preserved under the range. These analyses help lead us to our final goal, a complete 4D (3D spatial plus temporal) lithospheric-scale model of arch formation which will advance our understanding of the mechanisms

  11. Preliminary criteria for global flares in childhood-onset systemic lupus erythematosus.

    Science.gov (United States)

    Brunner, Hermine I; Mina, Rina; Pilkington, Clarissa; Beresford, Michael W; Reiff, Andreas; Levy, Deborah M; Tucker, Lori B; Eberhard, B Anne; Ravelli, Angelo; Schanberg, Laura E; Saad-Magalhaes, Claudia; Higgins, Gloria C; Onel, Karen; Singer, Nora G; von Scheven, Emily; Itert, Lukasz; Klein-Gitelman, Marisa S; Punaro, Marilynn; Ying, Jun; Giannini, Edward H

    2011-09-01

    To develop widely acceptable preliminary criteria of global flare for childhood-onset systemic lupus erythematosus (cSLE). Pediatric rheumatologists (n = 138) rated a total of 358 unique patient profiles with information about the cSLE flare descriptors from 2 consecutive visits: patient global assessment of well-being, physician global assessment of disease activity (MD-global), health-related quality of life, anti-double-stranded DNA antibodies, disease activity index scores, protein:creatinine (P:C) ratio, complement levels, and erythrocyte sedimentation rate (ESR). Based on 2,996 rater responses about the course of cSLE (baseline versus followup), the accuracy (sensitivity, specificity, and area under the receiver operating characteristic curve) of candidate flare criteria was assessed. An international consensus conference was held to rank these candidate flare criteria as per the American College of Rheumatology recommendations for the development and validation of criteria sets. The highest-ranked candidate criteria considered absolute changes (Δ) of the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) or British Isles Lupus Assessment Group (BILAG), MD-global, P:C ratio, and ESR; flare scores can be calculated (0.5 × ΔSLEDAI + 0.45 × ΔP:C ratio + 0.5 × ΔMD-global + 0.02 × ΔESR), where values of ≥1.04 are reflective of a flare. Similarly, BILAG-based flare scores (0.4 × ΔBILAG + 0.65 × ΔP:C ratio + 0.5 × ΔMD-global + 0.02 × ΔESR) of ≥1.15 were diagnostic of a flare. Flare scores increased with flare severity. Consensus has been reached on preliminary criteria for global flares in cSLE. Further validation studies are needed to confirm the usefulness of the cSLE flare criteria in research and for clinical care. Copyright © 2011 by the American College of Rheumatology.

  12. Dual-fuel, dual-throat engine preliminary analysis

    Science.gov (United States)

    Obrien, C. J.

    1979-01-01

    A propulsion system analysis of the dual fuel, dual throat engine for launch vehicle applications was conducted. Basic dual throat engine characterization data were obtained to allow vehicle optimization studies to be conducted. A preliminary baseline engine system was defined.

  13. Global analysis of solar neutrinos

    Energy Technology Data Exchange (ETDEWEB)

    Choubey, Sandhya [Department of Physics and Astronomy, University of Southampton, Highfield, Southampton S017 1BJ (United Kingdom)

    2003-08-01

    The recent data from SNO are analysed with the global data from the other solar neutrino experiments, first in a model independent way and then assuming two-flavour oscillations. Neutrino oscillations to active flavours can best explain the global data with the LMA solution emerging as the best-fit. However, transitions to 'mixed' states with up to 30% sterile mixture are still allowed at 1{sigma}.

  14. [Tuscan Chronic Care Model: a preliminary analysis].

    Science.gov (United States)

    Barbato, Angelo; Meggiolaro, Angela; Rossi, Luigi; Fioravanti, C; Palermita, F; La Torre, Giuseppe

    2015-01-01

    the aim of this study is to present a preliminary analysis of efficacy and effectiveness of a model of chronically ill care (Chronic Care Model, CCM). the analysis took into account 106 territorial modules, 1016 General Practitioners and 1,228,595 patients. The diagnostic and therapeutic pathways activated (PDTA), involved four chronic conditions, selected according to the prevalence and incidence, in Tuscany Region: Diabetes Mellitus (DM), Heart Failure (SC), Chronic Obstructive Pulmonary Disease (COPD) and stroke. Six epidemiological indicators of process and output were selected, in order to measure the model of care performed, before and after its application: adherence to specific follow-up for each pathology (use of clinical and laboratory indicators), annual average of expenditure per/capita/euro for diagnostic tests, in laboratory and instrumental, average expenditure per/capita/year for specialist visits; hospitalization rate for diseases related to the main pathology, hospitalization rate for long-term complications and rate of access to the emergency department (ED). Data were collected through the database; the differences before and after the intervention and between exposed and unexposed, were analyzed by method "Before-After (Controlled and Uncontrolled) Studies". The impact of the intervention was calculated as DD (difference of the differences). DM management showed an increased adhesion to follow-up (DD: +8.1%), and the use of laboratory diagnostics (DD: +4,9 €/year/pc), less hospitalization for long-term complications and for endocrine related diseases (DD respectively: 5.8/1000 and DD: +1.2/1000), finally a smaller increase of access to PS (DD: -1.6/1000), despite a slight increase of specialistic visits (DD: +0,38 €/year/pc). The management of SC initially showed a rising adherence to follow-up (DD: +2.3%), a decrease of specialist visits (DD:E 1.03 €/year/pc), hospitalization and access to PS for exacerbations (DD: -4.4/1000 and DD: -6

  15. A generalized preimage theorem in global analysis

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The concept of locally fine point and generalized regular valueof a C1 map between Banach spaces were carried over C1 map between Banach manifolds. Hence the preimage theorem, a principle constructing Banach manifolds in global analysis, is generalized.

  16. Global Analysis of Minimal Surfaces

    CERN Document Server

    Dierkes, Ulrich; Tromba, Anthony J

    2010-01-01

    Many properties of minimal surfaces are of a global nature, and this is already true for the results treated in the first two volumes of the treatise. Part I of the present book can be viewed as an extension of these results. For instance, the first two chapters deal with existence, regularity and uniqueness theorems for minimal surfaces with partially free boundaries. Here one of the main features is the possibility of 'edge-crawling' along free parts of the boundary. The third chapter deals with a priori estimates for minimal surfaces in higher dimensions and for minimizers of singular integ

  17. SILAC for global phosphoproteomic analysis.

    Science.gov (United States)

    Pimienta, Genaro; Chaerkady, Raghothama; Pandey, Akhilesh

    2009-01-01

    Establishing the phosphorylation pattern of proteins in a comprehensive fashion is an important goal of a majority of cell signaling projects. Phosphoproteomic strategies should be designed in such a manner as to identify sites of phosphorylation as well as to provide quantitative information about the extent of phosphorylation at the sites. In this chapter, we describe an experimental strategy that outlines such an approach using stable isotope labeling with amino acids in cell culture (SILAC) coupled to LC-MS/MS. We highlight the importance of quantitative strategies in signal transduction as a platform for a systematic and global elucidation of biological processes.

  18. Global Analysis of Flexible Risers

    DEFF Research Database (Denmark)

    Banke, Lars

    1996-01-01

    and thus resists the loading from the environment in a more suitable way.A flexible pipe is a composite structure, built up of several layers each having a specific function. Due to the flexibility, the response of the pipe in wave induced motions are governed by a complex hydroelastic set of differential...... parameters.The idea is to divide the riser system of riser and end fitting system into a global system including the riser and a local system of the bending stiffener and the end fitting. The forces at top of the riser shall be used as input for the design of the local system.This report introduces a non...

  19. Global two-channel AVHRR aerosol climatology: effects of stratospheric aerosols and preliminary comparisons with MODIS and MISR retrievals

    Energy Technology Data Exchange (ETDEWEB)

    Geogdzhayev, Igor V. [Department of Applied Physics and Applied Mathematics, Columbia University, 2880 Broadway, New York, NY 10025 (United States); NASA Goddard Institute for Space Studies, 2880 Broadway, New York, NY 10025 (United States); Mishchenko, Michael I. [NASA Goddard Institute for Space Studies, 2880 Broadway, New York, NY 10025 (United States)]. E-mail: crmim@giss.nasa.gov; Liu Li [NASA Goddard Institute for Space Studies, 2880 Broadway, New York, NY 10025 (United States); Department of Earth and Environmental Sciences, Columbia University, 2880 Broadway, New York, NY 10025 (United States); Remer, Lorraine [NASA Goddard Space Flight Center, Code 913, Greenbelt, MD 20771 (United States)

    2004-10-15

    We present an update on the status of the global climatology of the aerosol column optical thickness and Angstrom exponent derived from channel-1 and -2 radiances of the Advanced Very High Resolution Radiometer (AVHRR) in the framework of the Global Aerosol Climatology Project (GACP). The latest version of the climatology covers the period from July 1983 to September 2001 and is based on an adjusted value of the diffuse component of the ocean reflectance as derived from extensive comparisons with ship sun-photometer data. We use the updated GACP climatology and Stratospheric Aerosol and Gas Experiment (SAGE) data to analyze how stratospheric aerosols from major volcanic eruptions can affect the GACP aerosol product. One possible retrieval strategy based on the AVHRR channel-1 and -2 data alone is to infer both the stratospheric and the tropospheric aerosol optical thickness while assuming fixed microphysical models for both aerosol components. The second approach is to use the SAGE stratospheric aerosol data in order to constrain the AVHRR retrieval algorithm. We demonstrate that the second approach yields a consistent long-term record of the tropospheric aerosol optical thickness and Angstrom exponent. Preliminary comparisons of the GACP aerosol product with MODerate resolution Imaging Spectrometer (MODIS) and Multiangle Imaging Spectro-Radiometer aerosol retrievals show reasonable agreement, the GACP global monthly optical thickness being lower than the MODIS one by approximately 0.03. Larger differences are observed on a regional scale. Comparisons of the GACP and MODIS Angstrom exponent records are less conclusive and require further analysis.

  20. Conversion Preliminary Safety Analysis Report for the NIST Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Diamond, D. J. [Brookhaven National Lab. (BNL), Upton, NY (United States); Baek, J. S. [Brookhaven National Lab. (BNL), Upton, NY (United States); Hanson, A. L. [Brookhaven National Lab. (BNL), Upton, NY (United States); Cheng, L-Y [Brookhaven National Lab. (BNL), Upton, NY (United States); Brown, N. [Brookhaven National Lab. (BNL), Upton, NY (United States); Cuadra, A. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2015-01-30

    The NIST Center for Neutron Research (NCNR) is a reactor-laboratory complex providing the National Institute of Standards and Technology (NIST) and the nation with a world-class facility for the performance of neutron-based research. The heart of this facility is the NIST research reactor (aka NBSR); a heavy water moderated and cooled reactor operating at 20 MW. It is fueled with high-enriched uranium (HEU) fuel elements. A Global Threat Reduction Initiative (GTRI) program is underway to convert the reactor to low-enriched uranium (LEU) fuel. This program includes the qualification of the proposed fuel, uranium and molybdenum alloy foil clad in an aluminum alloy, and the development of the fabrication techniques. This report is a preliminary version of the Safety Analysis Report (SAR) that would be submitted to the U.S. Nuclear Regulatory Commission (NRC) for approval prior to conversion. The report follows the recommended format and content from the NRC codified in NUREG-1537, “Guidelines for Preparing and Reviewing Applications for the Licensing of Non-power Reactors,” Chapter 18, “Highly Enriched to Low-Enriched Uranium Conversions.” The emphasis in any conversion SAR is to explain the differences between the LEU and HEU cores and to show the acceptability of the new design; there is no need to repeat information regarding the current reactor that will not change upon conversion. Hence, as seen in the report, the bulk of the SAR is devoted to Chapter 4, Reactor Description, and Chapter 13, Safety Analysis.

  1. THE GLOBAL FINANCIAL MARKET: ANALYSIS AND PERSPECTIVES

    Directory of Open Access Journals (Sweden)

    Tatiana COLESNICOVA

    2015-04-01

    Full Text Available The assessment of the situation on the global financial market is analyzed in the paper. The actuality of this research proceeded from the reality facing the entire global financial system. The purpose of this work is to research the situation on the global financial market based on the complex analysis of the sector. In the process of developing of this work were used the following methods: comparative analysis, synthesis, logical analysis. The results from the well-known companies which provided each year the analysis and ratings between the high net worth individuals wealth levels and growth by world regions, the most successfully International Financial Centres, leading wealth managers, wealth management innovators, Private Banks of the year, Private Bankers of the year etc. are analyzed in the paper.

  2. Preliminary safety design analysis of KALIMER

    Energy Technology Data Exchange (ETDEWEB)

    Suk, Soo Dong; Kwon, Y. M.; Kim, K. D. [Korea Atomic Energy Research Institute, Taejon (Korea)

    1999-03-01

    The national long-term R and D program updated in 1997 requires Korea Atomic Energy Research Institute(KAERI) to complete by the year 2006 the basic design of Korea Advanced Liquid Metal Reactor (KALIMER), along with supporting R and D work, with the capability of resolving the issue of spent fuel storage as well as with significantly enhanced safety. KALIMER is a 150 MWe pool-type sodium cooled prototype reactor that uses metallic fuel. The conceptual design is currently under way to establish a self consistent design meeting a set of the major safety design requirements for accident prevention. Some of current emphasis include those for inherent and passive means of negative reactivity insertion and decay heat removal, high shutdown reliability, prevention of and protection from sodium chemical reaction, and high seismic margin, among others. All of these requirements affect the reactor design significantly and involve supporting R and D programs of substance. This document first introduces a set of safety design requirements and accident evaluation criteria established for the conceptual design of KALIMER and then summarizes some of the preliminary results of engineering and design analyses performed for the safety of KALIMER. 19 refs., 19 figs., 6 tabs. (Author)

  3. Preliminary Concept of Operations for a Global Cylinder Identification and Monitoring System

    Energy Technology Data Exchange (ETDEWEB)

    Whitaker, J. M. [ORNL; White-Horton, J. L. [ORNL; Morgan, J. B. [InSolves Associates

    2013-08-01

    This report describes a preliminary concept of operations for a Global Cylinder Identification and Monitoring System that could improve the efficiency of the International Atomic Energy Agency (IAEA) in conducting its current inspection activities and could provide a capability to substantially increase its ability to detect credible diversion scenarios and undeclared production pathways involving UF6 cylinders. There exist concerns that a proliferant State with access to enrichment technology could obtain a cylinder containing natural or low-enriched uranium hexafluoride (UF6) and produce a significant quantity (SQ)1 of highly enriched uranium in as little as 30 days. The National Nuclear Security Administration (NNSA) through the Next Generation Safeguards Initiative sponsored a multi-laboratory team to develop an integrated system that provides for detecting scenarios involving 1) diverting an entire declared cylinder for enrichment at a clandestine facility, 2) misusing a declared cylinder at a safeguarded facility, and 3) using an undeclared cylinder at a safeguarded facility. An important objective in developing this integrated system was to improve the timeliness for detecting the cylinder diversion and undeclared production scenarios. Developing this preliminary concept required in-depth analyses of current operational and safeguards practices at conversion, enrichment, and fuel fabrication facilities. The analyses evaluated the processing, movement, and storage of cylinders at the facilities; the movement of cylinders between facilities (including cylinder fabrication); and the misuse of safeguarded facilities.

  4. Preliminary analysis of patent trends for magnetic fusion technology

    Energy Technology Data Exchange (ETDEWEB)

    Levine, L.O.; Ashton, W.B.; Campbell, R.S.

    1984-02-01

    This study presents a preliminary analysis of development trends in magnetic fusion technology based on data from US patents. The research is limited to identification and description of general patent activity and ownership characteristics for 373 patents. The results suggest that more detailed studies of fusion patents could provide useful R and D planning information.

  5. Preliminary analysis of alternative fuel cycles for proliferation evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Steindler, M. J.; Ripfel, H. C.F.; Rainey, R. H.

    1977-01-01

    The ERDA Division of Nuclear Research and Applications proposed 67 nuclear fuel cycles for assessment as to their nonproliferation potential. The object of the assessment was to determine which fuel cycles pose inherently low risk for nuclear weapon proliferation while retaining the major benefits of nuclear energy. This report is a preliminary analysis of these fuel cycles to develop the fuel-recycle data that will complement reactor data, environmental data, and political considerations, which must be included in the overall evaluation. This report presents the preliminary evaluations from ANL, HEDL, ORNL, and SRL and is the basis for a continuing in-depth study. (DLC)

  6. Bundled Hybrid Offset Riser Global Strength Analysis

    Institute of Scientific and Technical Information of China (English)

    William C.Webster; Zhuang Kang; Wenzhou Liang; Youwei Kang; Liping Sun

    2011-01-01

    Bundled hybrid offset riser(BHOR)global strength analysis,which is more complex than single line offset riser global strength analysis,was carried out in this paper.At first,the equivalent theory is used to deal with BHOR,and then its global strength in manifold cases was analyzed,along with the use of a three-dimensional nonlinear time domain finite element program.So the max bending stress,max circumferential stress,and max axial stress in the BHOR bundle main section(BMS)were obtained,and the values of these three stresses in each riser were obtained through the "stress distribution method".Finally,the Max Von Mises stress in each riser was given and a check was made whether or not they met the demand.This paper provides a reference for strength analysis of the bundled hybrid offset riser and some other bundled pipelines.

  7. Preliminary Integrated Safety Analysis Status Report

    Energy Technology Data Exchange (ETDEWEB)

    D. Gwyn

    2001-04-01

    This report provides the status of the potential Monitored Geologic Repository (MGR) Integrated Safety Analysis (EA) by identifying the initial work scope scheduled for completion during the ISA development period, the schedules associated with the tasks identified, safety analysis issues encountered, and a summary of accomplishments during the reporting period. This status covers the period from October 1, 2000 through March 30, 2001.

  8. A global DGLAP analysis of nuclear PDFs

    Science.gov (United States)

    Eskola, K. J.; Kolhinen, V. J.; Paukkunen, H.; Salgado, C. A.

    2008-05-01

    In this talk, we shortly report results from our recent global DGLAP analysis of nuclear parton distributions. This is an extension of our former EKS98-analysis improved with an automated χ2 minimization procedure and uncertainty estimates. Although our new analysis show no significant deviation from EKS98, a sign of a significantly stronger gluon shadowing could be seen in the RHIC BRAHMS data.

  9. Preliminary EEG study of protective effects of Tebonin in transient global cerebral ischemia in rats

    DEFF Research Database (Denmark)

    Zagrean, L; Vatasescu, R; Munteanu, A M

    2000-01-01

    and metabolism. The objective of this study was to investigate the effects of preventive treatment with Ginkgo biloba extract (EGb 761--Tebonin) in cerebral global ischemia and reperfusion in rats using computerized EEG analysis. Ginkgo biloba extract, known to be, in vitro, a free radicals scavanger and a PAF.......0015). Computerized spectral analysis of EEG has shown that the percentage of slow waves at 10 minutes after reperfusion was 117% higher in control group than in Ginkgo biloba group (p

  10. Fort Drum Preliminary Fiscal Impact Analysis.

    Science.gov (United States)

    1986-02-01

    of inmigrants 0 Fiscal histories, projections, and impacts for counties, cities, towns, villages, school districts, and the state. The results of...distribution of the inmigrating population within the three counties. Thus, an accurate forecast of the expected distribution of the inmigrating population is a...The distribution of inmigration to the school districts was made using the analysis explained in Chapter 3. Children associated with 800 new on-post

  11. Preliminary analysis of turbochargers rotors dynamic behaviour

    Science.gov (United States)

    Monoranu, R.; Ştirbu, C.; Bujoreanu, C.

    2016-08-01

    Turbocharger rotors for the spark and compression ignition engines are resistant steels manufactured in order to support the exhaust gas temperatures exceeding 1200 K. In fact, the mechanical stress is not large as the power consumption of these systems is up to 10 kW, but the operating speeds are high, ranging between 30000 ÷ 250000 rpm. Therefore, the correct turbochargers functioning involves, even from the design stage, the accurate evaluation of the temperature effects, of the turbine torque due to the engine exhaust gases and of the vibration system behaviour caused by very high operating speeds. In addition, the turbocharger lubrication complicates the model, because the classical hydrodynamic theory cannot be applied to evaluate the floating bush bearings. The paper proposes a FEM study using CATIA environment, both as modeling medium and as tool for the numerical analysis, in order to highlight the turbocharger complex behaviour. An accurate design may prevent some major issues which can occur during its operation.

  12. Preliminary Analysis of Helicopter Options to Support Tunisian Counterterrorism Operations

    Science.gov (United States)

    2016-04-27

    results of the current analysis and in Mouton et al., 2015, is the relative cost -effectiveness between the CH-47D and the Mi-17v5. In the previous...helicopters from Sikorsky to fulfill a number of roles in counterterrorism operations. Rising costs and delays in delivery raised the question of...whether other cost -effective options exist to meet Tunisia’s helicopter requirement. Approach Our team conducted a preliminary assessment of

  13. Preliminary analysis of Alvito-Odivelas reservoir system operation under climate change scenarios

    OpenAIRE

    2008-01-01

    The present study provides a preliminary analysis of the impact of climate change on a water resources system of Alentejo region in the South of Portugal. Regional climate model HadRM3P forced by the Global Circulation Model HadAM3P A2 of the Hadley Centre, is used to derive temperature and precipitation data, which in turn is used as input to hydrological model (SHETRAN) for simulation of future streamflow. Dynamic programming based models are used for operation of reservoir system in order ...

  14. Plume and surface feature structure and compositional effects on Europa's global exosphere: Preliminary Europa mission predictions

    Science.gov (United States)

    Teolis, B. D.; Wyrick, D. Y.; Bouquet, A.; Magee, B. A.; Waite, J. H.

    2017-03-01

    A Europa plume source, if present, may produce a global exosphere with complex spatial structure and temporal variability in its density and composition. To investigate this interaction we have integrated a water plume source containing multiple organic and nitrile species into a Europan Monte Carlo exosphere model, considering the effect of Europa's gravity in returning plume ejecta to the surface, and the subsequent spreading of adsorbed and exospheric material by thermal desorption and re-sputtering across the entire body. We consider sputtered, radiolytic and potential plume sources, together with surface adsorption, regolith diffusion, polar cold trapping, and re-sputtering of adsorbed materials, and examine the spatial distribution and temporal evolution of the exospheric density and composition. These models provide a predictive basis for telescopic observations (e.g. HST, JWST) and planned missions to the Jovian system by NASA and ESA. We apply spacecraft trajectories to our model to explore possible exospheric compositions which may be encountered along proposed flybys of Europa to inform the spatial and temporal relationship of spacecraft measurements to surface and plume source compositions. For the present preliminary study, we have considered four cases: Case A: an equatorial flyby through a sputtered only exosphere (no plumes), Case B: a flyby over a localized sputtered 'macula' terrain enriched in non-ice species, Case C: a south polar plume with an Enceladus-like composition, equatorial flyby, and Case D: a south polar plume, flyby directly through the plume.

  15. Beta Gyres in Global Analysis Fields

    Institute of Scientific and Technical Information of China (English)

    Sun-Hee KIM; H.Joe KWON; R.L.ELSBERRY

    2009-01-01

    A three-component decomposition is applied to global analysis data to show the existence of a beta gyre,which causes Tropical Cyclone (TC) to drift from a large-scale environmental steering current.Analyses from the Global Data Assimilation and Prediction System (GDAPS) of the Korea Meteorological Administration (KMA),the Global Forecast System (GFS) of NCEP,and the Navy Operational Global Atmospheric Prediction System (NOGAPS) are used in this study.The structure of the beta gyre obtained in our analyses is in good agreement with the theoretical structure,with a cyclonic circulation to the southwest of the TC center,an anticyclonic circulation to the northeast,and a ventilation flow directed northwestward near the center.The circulation of the beta gyre is strongest at the 850-hPa level where the cyclonically swirling primary circulation is strongest,and decreases with height,in a pyramid shape similar to the primary circulation.The individual structure of the beta gyre is case- and model-dependent.At a certain analysis time,one model may clearly reveal a well-defined beta gyre,but the other models may not.Within one model,the beta gyre may be well defined at some analysis times,but not at other times.The structure of the beta gyre in the analysis field is determined by the nature of the vortex initialization scheme and the model behavior during the 6-h forecast in the operational data assimilation cycle.

  16. Conference on Convex Analysis and Global Optimization

    CERN Document Server

    Pardalos, Panos

    2001-01-01

    There has been much recent progress in global optimization algo­ rithms for nonconvex continuous and discrete problems from both a theoretical and a practical perspective. Convex analysis plays a fun­ damental role in the analysis and development of global optimization algorithms. This is due essentially to the fact that virtually all noncon­ vex optimization problems can be described using differences of convex functions and differences of convex sets. A conference on Convex Analysis and Global Optimization was held during June 5 -9, 2000 at Pythagorion, Samos, Greece. The conference was honoring the memory of C. Caratheodory (1873-1950) and was en­ dorsed by the Mathematical Programming Society (MPS) and by the Society for Industrial and Applied Mathematics (SIAM) Activity Group in Optimization. The conference was sponsored by the European Union (through the EPEAEK program), the Department of Mathematics of the Aegean University and the Center for Applied Optimization of the University of Florida, by th...

  17. Towards More Efficient and Effective Global Sensitivity Analysis

    Science.gov (United States)

    Razavi, Saman; Gupta, Hoshin

    2014-05-01

    Sensitivity analysis (SA) is an important paradigm in the context of model development and application. There are a variety of approaches towards sensitivity analysis that formally describe different "intuitive" understandings of the sensitivity of a single or multiple model responses to different factors such as model parameters or forcings. These approaches are based on different philosophies and theoretical definitions of sensitivity and range from simple local derivatives to rigorous Sobol-type analysis-of-variance approaches. In general, different SA methods focus and identify different properties of the model response and may lead to different, sometimes even conflicting conclusions about the underlying sensitivities. This presentation revisits the theoretical basis for sensitivity analysis, critically evaluates the existing approaches in the literature, and demonstrates their shortcomings through simple examples. Important properties of response surfaces that are associated with the understanding and interpretation of sensitivities are outlined. A new approach towards global sensitivity analysis is developed that attempts to encompass the important, sensitivity-related properties of response surfaces. Preliminary results show that the new approach is superior to the standard approaches in the literature in terms of effectiveness and efficiency.

  18. Dynamical Analysis of the Global Warming

    Directory of Open Access Journals (Sweden)

    J. A. Tenreiro Machado

    2012-01-01

    Full Text Available Global warming is a major concern nowadays. Weather conditions are changing, and it seems that human activity is one of the main causes. In fact, since the beginning of the industrial revolution, the burning of fossil fuels has increased the nonnatural emissions of carbon dioxide to the atmosphere. Carbon dioxide is a greenhouse gas that absorbs the infrared radiation produced by the reflection of the sunlight on the Earth’s surface, trapping the heat in the atmosphere. Global warming and the associated climate changes are being the subject of intensive research due to their major impact on social, economic, and health aspects of human life. This paper studies the global warming trend in the perspective of dynamical systems and fractional calculus, which is a new standpoint in this context. Worldwide distributed meteorological stations and temperature records for the last 100 years are analysed. It is shown that the application of Fourier transforms and power law trend lines leads to an assertive representation of the global warming dynamics and a simpler analysis of its characteristics.

  19. Progress in the NNPDF global analysis

    CERN Document Server

    Deans, Christopher S

    2013-01-01

    We report on recent progress in the NNPDF framework of global PDF analysis. The NNPDF2.3 set is the first and only available PDF set with includes LHC data. A recent benchmark comparison of NNPDF2.3 and all other modern NNLO PDF sets with LHC data was performed. We have also studied theoretical uncertainties due to heavy quark renormalization schemes, higher twists and deuterium corrections in PDFs. Finally, we report on the release of positive definite PDF sets, based on the NNPDF2.3 analysis, specially suited for use in Monte Carlo event generators.

  20. Preliminary Analysis of HL-2A Global Energy Confinement

    Institute of Scientific and Technical Information of China (English)

    DONG Chunfeng; CUI Zhengying; JI Xiaoquan; ZHOU Hangyu; FENG Beibin; SUN Hongjuan; LI Yonggao; YANG Qingwei

    2009-01-01

    Energy confinement time taken from 135 discharges of the 2006 campaign in HL-2A is studied.The.data obtained from the measurements are verified by comparing diamagnetic energy with the electronic kinetic energy calculated from both the electron temperature and density profiles.Two data sets for supporting the ITER L-Mode confinement database are generated from the 2006 campaign.The dependence of гE on the line-averaged electron density during ohmic phases is analysed.The comparison of гE in electron cyclotron resonance heating(ECRH) plasma as well as the existing ITER L-mode scalings is made.The results show that the energy confinement time is consistent with the ITER L-mode scalings.

  1. Global stability analysis of axisymmetric boundary layers

    CERN Document Server

    Vinod, N

    2016-01-01

    This paper presents the linear global stability analysis of the incompressible axisymmetric boundary layer on a circular cylinder. The base flow is parallel to the axis of the cylinder at inlet. The pressure gradient is zero in the streamwise direction. The base flow velocity profile is fully non-parallel and non-similar in nature. The boundary layer grows continuously in the spatial directions. Linearized Navier-Stokes(LNS) equations are derived for the disturbance flow quantities in the cylindrical polar coordinates. The LNS equations along with homogeneous boundary conditions forms a generalized eigenvalues problem. Since the base flow is axisymmetric, the disturbances are periodic in azimuthal direction. Chebyshev spectral collocation method and Arnoldi's iterative algorithm is used for the solution of the general eigenvalues problem. The global temporal modes are computed for the range of Reynolds numbers and different azimuthal wave numbers. The largest imaginary part of the computed eigenmodes are nega...

  2. Conceptual risk assessment framework for global change risk analysis SRP

    CSIR Research Space (South Africa)

    Elphinstone, CD

    2007-12-01

    Full Text Available This report is submitted as a deliverable of the SRP project Global Change Risk Analysis which aims at applying risk analysis as a unifying notion for quantifying and communicating threats to ecosystem services originating from global change...

  3. A preliminary study on the global land annual precipitation associated with ENSO during 1948-2000

    Science.gov (United States)

    Shi, N.; Chen, L. W.; Xia, D. D.

    2002-11-01

    The global land monthly precipitation data (PREC / L) are used to investigate the relation between the global land annual precipitation and ENSO during 1948-2000, and the results of composite analysis are tested with Monte Carlo simulations. Results indicate that the global land annual precipitation was significantly reduced in large scale areas in warm event years; the areas were the equatorial West Pacific, North China; equatorial Central America; North Bengal Bay and Nepal; East Australia; West India and South Pakistan; the district east of the Lena River; West Europe; and Wilkes Land of Antarctica. In contrast to this, the areas where precipitation increased in warm event years were less, and mainly in Chile and Argentina of South America; Somali, Kenya, and Tanzania of East Africa; Turkey, Iraq, and Iran of the Middle East; Libya and Nigeria of North Africa; Namibia of Southwest Africa; and Botswana and Zimbabwe of southern Africa. Statistical tests show that in warm event years, the area where the land annual precipitation was reduced was larger than the area where the annual precipitation increased, and the reduction in precipitation was more significant than the increase. The results in this paper are compared with previous studies. It is also pointed out that the interdecadal change of ENSO had no significant effect on the interdecadal variation of precipitation in the above regions. However, the warm events of El Nino affected the droughts in East Australia and North China more after the 1980s than before.

  4. A preliminary study on the global land annual precipitation associated with ENSO during 1948 2000

    Science.gov (United States)

    Neng, Shi; Luwen, Chen; Dongdong, Xia

    2002-11-01

    The global land monthly precipitation data (PREC/L) are used to investigate the relation between the global land annual precipitation and ENSO during 1948 2000, and the results of composite analysis are tested with Monte Carlo simulations. Results indicate that the global land annual precipitation was significantly reduced in large scale areas in warm event years; the areas were the equatorial West Pacific, North China; equatorial Central America; North Bengal Bay and Nepal; East Australia; West India and South Pakistan; the district east of the Lena River; West Europe; and Wilkes Land of Antarctica. In contrast to this, the areas where precipitation increased in warm event years were less, and mainly in Chile and Argentina of South America; Somali, Kenya, and Tanzania of East Africa; Turkey, Iraq, and Iran of the Middle East; Libya and Nigeria of North Africa; Namibia of Southwest Africa; and Botswana and Zimbabwe of southern Africa. Statistical tests show that in warm event years, the area where the land annual precipitation was reduced was larger than the area where the annual precipitation increased, and the reduction in precipitation was more significant than the increase. The results in this paper are compared with previous studies. It is also pointed out that the interdecadal change of ENSO had no significant effect on the interdecadal variation of precipitation in the above regions. However, the warm events of El Nino affected the droughts in East Australia and North China more after the 1980s than before.

  5. NRT Rotor Structural / Aeroelastic Analysis for the Preliminary Design Review

    Energy Technology Data Exchange (ETDEWEB)

    Ennis, Brandon Lee [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Paquette, Joshua A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-10-01

    This document describes the initial structural design for the National Rotor Testbed blade as presented during the preliminary design review at Sandia National Laboratories on October 28- 29, 2015. The document summarizes the structural and aeroelastic requirements placed on the NRT rotor for satisfactory deployment at the DOE/SNL SWiFT experimental facility to produce high-quality datasets for wind turbine model validation. The method and result of the NRT blade structural optimization is also presented within this report, along with analysis of its satisfaction of the design requirements.

  6. Preliminary Analysis of ULPC Light Curves Using Fourier Decomposition Technique

    CERN Document Server

    Ngeow, Chow-Choong; Kanbur, Shashi; Barrett, Brittany; Lin, Bin

    2013-01-01

    Recent work on Ultra Long Period Cepheids (ULPCs) has suggested their usefulness as a distance indicator, but has not commented on their relationship as compared with other types of variable stars. In this work, we use Fourier analysis to quantify the structure of ULPC light curves and compare them to Classical Cepheids and Mira variables. Our preliminary results suggest that the low order Fourier parameters of ULPCs show a continuous trend defined by Classical Cepheids after the resonance around 10 days. However their Fourier parameters also overlapped with those from Miras, which make the classification of long period variable stars difficult based on the light curves information alone.

  7. Determinants of Trade Credit: A Preliminary Analysis on Construction Sector

    Directory of Open Access Journals (Sweden)

    Nicoleta Barbuta-Misu

    2016-07-01

    Full Text Available This paper introduces a preliminary analysis of the correlations between trade credit and some selected measures of financial performance for a sample of 958 firms acting in the construction sector. The examined period covers 2004-2013. The sample derived from Amadeus database contains firms that have sold and bought on credit. Results showed that larger firms offered and used more credit than counterparties. Firms offered and used in same time credit, but not in same level. Firms with higher return on assets and profit margin used and offered less credit from suppliers, respectively to clients. Moreover, more liquid firms used less trade payables.

  8. The global analysis of DEER data.

    Science.gov (United States)

    Brandon, Suzanne; Beth, Albert H; Hustedt, Eric J

    2012-05-01

    Double Electron-Electron Resonance (DEER) has emerged as a powerful technique for measuring long range distances and distance distributions between paramagnetic centers in biomolecules. This information can then be used to characterize functionally relevant structural and dynamic properties of biological molecules and their macromolecular assemblies. Approaches have been developed for analyzing experimental data from standard four-pulse DEER experiments to extract distance distributions. However, these methods typically use an a priori baseline correction to account for background signals. In the current work an approach is described for direct fitting of the DEER signal using a model for the distance distribution which permits a rigorous error analysis of the fitting parameters. Moreover, this approach does not require a priori background correction of the experimental data and can take into account excluded volume effects on the background signal when necessary. The global analysis of multiple DEER data sets is also demonstrated. Global analysis has the potential to provide new capabilities for extracting distance distributions and additional structural parameters in a wide range of studies.

  9. A global analysis of neutrino oscillations

    Energy Technology Data Exchange (ETDEWEB)

    Fogli, G.L. [Dipartimento Interateneo di Fisica “Michelangelo Merlin”, Via Amendola 173, 70126 Bari (Italy); Istituto Nazionale di Fisica Nucleare, Sezione di Bari, Via Orabona 4, 70126 Bari (Italy); Lisi, E. [Istituto Nazionale di Fisica Nucleare, Sezione di Bari, Via Orabona 4, 70126 Bari (Italy); Marrone, A. [Dipartimento Interateneo di Fisica “Michelangelo Merlin”, Via Amendola 173, 70126 Bari (Italy); Istituto Nazionale di Fisica Nucleare, Sezione di Bari, Via Orabona 4, 70126 Bari (Italy); Montanino, D. [Dipartimento di Matematica e Fisica “Ennio De Giorgi”, Via Arnesano, 73100 Lecce (Italy); Istituto Nazionale di Fisica Nucleare, Sezione di Lecce, Via Arnesano, 73100 Lecce (Italy); Palazzo, A. [Cluster of Excellence, Origin and Structure of the Universe, Technische Universität München, Boltzmannstraße 2, D-85748 Garching (Germany); Rotunno, A.M. [Dipartimento Interateneo di Fisica “Michelangelo Merlin”, Via Amendola 173, 70126 Bari (Italy)

    2013-02-15

    We present a global analysis of neutrino oscillation data, including high-precision measurements of the neutrino mixing angle θ{sub 13} at reactor experiments, which have confirmed previous indications in favor of θ{sub 13}>0. Recent data presented at this Conference are also included. We focus on the correlations between θ{sub 13} and the mixing angle θ{sub 23}, as well as between θ{sub 13} and the neutrino CP-violation phase δ. We find interesting indications for θ{sub 23}<π/4 and possible hints for δ∼π, with no significant difference between normal and inverted mass hierarchy.

  10. CONTENT ANALYSIS, DISCOURSE ANALYSIS, AND CONVERSATION ANALYSIS: PRELIMINARY STUDY ON CONCEPTUAL AND THEORETICAL METHODOLOGICAL DIFFERENCES

    Directory of Open Access Journals (Sweden)

    Anderson Tiago Peixoto Gonçalves

    2016-08-01

    Full Text Available This theoretical essay aims to reflect on three models of text interpretation used in qualitative research, which is often confused in its concepts and methodologies (Content Analysis, Discourse Analysis, and Conversation Analysis. After the presentation of the concepts, the essay proposes a preliminary discussion on conceptual and theoretical methodological differences perceived between them. A review of the literature was performed to support the conceptual and theoretical methodological discussion. It could be verified that the models have differences related to the type of strategy used in the treatment of texts, the type of approach, and the appropriate theoretical position.

  11. Enhanced Accident Tolerant Fuels for LWRS - A Preliminary Systems Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Gilles Youinou; R. Sonat Sen

    2013-09-01

    The severe accident at Fukushima Daiichi nuclear plants illustrates the need for continuous improvements through developing and implementing technologies that contribute to safe, reliable and cost-effective operation of the nuclear fleet. Development of enhanced accident tolerant fuel contributes to this effort. These fuels, in comparison with the standard zircaloy – UO2 system currently used by the LWR industry, should be designed such that they tolerate loss of active cooling in the core for a longer time period (depending on the LWR system and accident scenario) while maintaining or improving the fuel performance during normal operations, operational transients, and design-basis events. This report presents a preliminary systems analysis related to most of these concepts. The potential impacts of these innovative LWR fuels on the front-end of the fuel cycle, on the reactor operation and on the back-end of the fuel cycle are succinctly described without having the pretension of being exhaustive. Since the design of these various concepts is still a work in progress, this analysis can only be preliminary and could be updated as the designs converge on their respective final version.

  12. Terrestrial Carbon Sequestration with Biochar: A Preliminary Assessment of its Global Potential

    Science.gov (United States)

    Amonette, J.; Lehmann, J.; Joseph, S.

    2007-12-01

    , while sequestering 0.5 Gt as biochar. Of the 60.6 Gt/yr of biomass that is fixed in usable form, we estimate that perhaps 10% of it (6.1 Gt/yr) could become available in one form or another (crop and forestry residues, and animal waste) for pyrolysis. This level of pyrolysis would offset 1.8 Gt/yr of fossil C, and sequester 3.0 Gt/yr as biochar, enough to halt the increase and actually decrease the level of atmospheric C by 0.7 Gt/yr. Even at half this level (i.e., 5% of annually fixed biomass), pyrolysis would be sufficient to decrease the global C cycle imbalance by 2.4 Gt/yr and in combination with other sequestration options help to achieve the minimum goal of C neutrality. Clearly, the potential contribution of biochar technology is large, perhaps large enough to mitigate climate change alone. However, this preliminary assessment is tempered by several unknowns. Research is needed to further define the impacts of biochar amendments on soil biota, productivity, and greenhouse gas production. For example, there is some evidence that N2O and CH4 production is decreased by biochar amendments, but the mechanisms responsible are unknown. The impact of different types of biochar and pyrolysis conditions also needs to be determined. Lastly, total accounting for greenhouse gas emissions coupled with economic analyses to determine the economic potential of the technology under various scenarios is essential.

  13. Electronic Warfare M-on-N Digital Simulation Logging Requirements and HDF5: A Preliminary Analysis

    Science.gov (United States)

    2017-04-12

    E. Jarvis Electronic Warfare M-on- N Digital Simulation Logging Requirements and HDF5: A Preliminary Analysis Advanced Techniques Branch Tactical...12-04-2017 NRL Memorandum Report Electronic Warfare M-on- N Digital Simulation Logging Requirements and HDF5: A Preliminary Analysis Donald E...ELECTRONIC WARFARE M-ON- N DIGITAL SIMULATION LOGGING REQUIREMENTS AND HDF5: A PRELIMINARY ANALYSIS 1. INTRODUCTION HDF5 technology [Folk] has been

  14. Preliminary hazards analysis of thermal scrap stabilization system. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, W.S.

    1994-08-23

    This preliminary analysis examined the HA-21I glovebox and its supporting systems for potential process hazards. Upon further analysis, the thermal stabilization system has been installed in gloveboxes HC-21A and HC-21C. The use of HC-21C and HC-21A simplified the initial safety analysis. In addition, these gloveboxes were cleaner and required less modification for operation than glovebox HA-21I. While this document refers to glovebox HA-21I for the hazards analysis performed, glovebox HC-21C is sufficiently similar that the following analysis is also valid for HC-21C. This hazards analysis document is being re-released as revision 1 to include the updated flowsheet document (Appendix C) and the updated design basis (Appendix D). The revised Process Flow Schematic has also been included (Appendix E). This Current revision incorporates the recommendations provided from the original hazards analysis as well. The System Design Description (SDD) has also been appended (Appendix H) to document the bases for Safety Classification of thermal stabilization equipment.

  15. Analysis preliminary phytochemical raw extract of leaves Nephrolepis pectinata

    Directory of Open Access Journals (Sweden)

    Natally Marreiros Gomes

    2017-06-01

    Full Text Available The Nephrolepis pectinata popularly known as paulista fern, ladder-heaven, cat tail, belongs to the family Davalliaceae. For the beauty of the arrangements of their leaves ferns are quite commercialized in Brazil, however, have not been described in the literature studies on their pharmacological potential. Thus, the objective of this research was to analyze the phytochemical properties of the crude extract of the leaves of Nephrolepis pectinata. To perform the phytochemical analysis were initially made the collection of the vegetable, preparation of voucher specimen, washing, drying and grinding. Then, extraction by percolation method and end the phytochemical analysis. Preliminary results phytochemicals the crude extract of the leaves of Nephrolepis pectinata tested positive for reducing sugars, phenols/tannins (catechins tannins and catechins.

  16. HMI global helioseismology data analysis pipeline

    Science.gov (United States)

    Larson, Tim; Schou, Jesper

    2011-01-01

    The HMI global helioseismology data analysis pipeline is based largely on the MDI medium-l program. All of the modules that ran in the SOI Science Support Center have been ported for use in the SDO Joint Science Operations Center (JSOC) and given greater functionality. Many errors and approximations which are present in the standard MDI pipeline have been corrected and improvements have been added. Scripts have been written to automate the submission of compute jobs to our local cluster; it is now possible to go from dopplergrams to mode parameters with the push of a button. JSOC dataseries have been created to hold all intermediate data products, timeseries, window functions, and mode parameters. Here we discuss the operation of the pipeline, the structure of the data it generates, and access to the same.

  17. Electric dipole moments: A global analysis

    Science.gov (United States)

    Chupp, Timothy; Ramsey-Musolf, Michael

    2015-03-01

    We perform a global analysis of searches for the permanent electric dipole moments (EDMs) of the neutron, neutral atoms, and molecules in terms of six leptonic, semileptonic, and nonleptonic interactions involving photons, electrons, pions, and nucleons. By translating the results into fundamental charge-conjugation-parity symmetry (CP) violating effective interactions through dimension six involving standard model particles, we obtain rough lower bounds on the scale of beyond the standard model CP-violating interactions ranging from 1.5 TeV for the electron EDM to 1300 TeV for the nuclear spin-independent electron-quark interaction. We show that planned future measurements involving systems or combinations of systems with complementary sensitivities to the low-energy parameters may extend the mass reach by an order of magnitude or more.

  18. Global analysis of posttranslational protein arginylation.

    Directory of Open Access Journals (Sweden)

    Catherine C L Wong

    2007-10-01

    Full Text Available Posttranslational arginylation is critical for embryogenesis, cardiovascular development, and angiogenesis, but its molecular effects and the identity of proteins arginylated in vivo are largely unknown. Here we report a global analysis of this modification on the protein level and identification of 43 proteins arginylated in vivo on highly specific sites. Our data demonstrate that unlike previously believed, arginylation can occur on any N-terminally exposed residue likely defined by a structural recognition motif on the protein surface, and that it preferentially affects a number of physiological systems, including cytoskeleton and primary metabolic pathways. The results of our study suggest that protein arginylation is a general mechanism for regulation of protein structure and function and outline the potential role of protein arginylation in cell metabolism and embryonic development.

  19. Analysis of Globalization, the Planet and Education

    Science.gov (United States)

    Tsegay, Samson Maekele

    2016-01-01

    Thorough the framework of theories analyzing globalization and education, this paper focuses on the intersection among globalization, the environment and education. This paper critically analyzes how globalization could affect environmental devastation, and explore the role of pedagogies that could foster planetary citizenship by exposing…

  20. The Impact of 2008 Global Financial Crisis on the Performance of Selected Indonesian Stocks: A Preliminary Study

    Directory of Open Access Journals (Sweden)

    Edwin Suparman

    2014-08-01

    Full Text Available This research is a preliminary study that analyzes the impact of the US financial markets on Indonesian financial markets during the 2008 global financial crisis. It specifically investigates the occurrence of contagion effect in the Indonesian IHSG index and selected LQ45 stocks with the US S&P500 index by the measurement of correlation using simple correlation, EWMA, OGARCH, and DCC GARCH. It also attempts to discuss on the decoupling of Indonesian market and provide recommendations on dealing with future similar events.

  1. Solar Stirling power generation - Systems analysis and preliminary tests

    Science.gov (United States)

    Selcuk, M. K.; Wu, Y.-C.; Moynihan, P. I.; Day, F. D., III

    1977-01-01

    The feasibility of an electric power generation system utilizing a sun-tracking parabolic concentrator and a Stirling engine/linear alternator is being evaluated. Performance predictions and cost analysis of a proposed large distributed system are discussed. Design details and preliminary test results are presented for a 9.5 ft diameter parabolic dish at the Jet Propulsion Laboratory (Caltech) Table Mountain Test Facility. Low temperature calorimetric measurements were conducted to evaluate the concentrator performance, and a helium flow system is being used to test the solar receiver at anticipated working fluid temperatures (up to 650 or 1200 C) to evaluate the receiver thermal performance. The receiver body is designed to adapt to a free-piston Stirling engine which powers a linear alternator assembly for direct electric power generation. During the next phase of the program, experiments with an engine and receiver integrated into the concentrator assembly are planned.

  2. Primate phylogeny studied by comparative determinant analysis. A preliminary report.

    Science.gov (United States)

    Bauer, K

    1993-01-01

    In this preliminary report the divergence times for the major primate groups are given, calculated from a study by comparative determinant analysis of 69 proteins (equaling 0.1% of the whole genetic information). With an origin of the primate order set at 80 million years before present, the ages of the last common ancestors (LCAs) of man and the major primate groups obtained this way are as follows: Pan troglodytes 5.2; Gorilla gorilla 7.4; Pongo pygmaeus 19.2; Hylobates lar 20.3; Old World monkeys 31.4; Lagothrix lagotricha 46.0; Cebus albifrons 59.5; three lemur species 67.0, and Galago crassicaudatus 73.3 million years. The LCA results and the approach are shortly discussed. A full account of this extended investigation including results on nonprimate mammals and on the determinant structures and the immunologically derived evolutionary rates of the proteins analyzed will be published elsewhere.

  3. PRELIMINARY PHYTOCHEMICAL ANALYSIS OF ACTINIOPTERIS RADIATA (SWARTZ LINK.

    Directory of Open Access Journals (Sweden)

    R. Manonmani

    2013-06-01

    Full Text Available The objective of the present study was to find out the presence of preliminary phytochemicals in six different solvent extracts of Actiniopteris radiata (Swartz link. by qualitative screening methods. The solvent used for the extraction of leaf and rhizome powder were ethanol, petroleum ether, chloroform, acetone, DMSO and aqueous. The secondary metabolites such as steroids, triterpenoids, reducing sugars, sugars, alkaloids, phenolic compounds, catechins, flavonoids, saponins, tannins, anthroquinones and amino acids were screened by using standard methods. The phytochemical analysis of the ethanolic extract of both (leaf & rhizome revealed the presence of most active constituents than the other solvents. The ethanolic rhizome extracts of Actiniopteris radiata showed higher amount of phytochemicals when compared with the ethanolic leaf extracts.

  4. Development of the Global Disability Scale (Glo.Di.S: preliminary results

    Directory of Open Access Journals (Sweden)

    Fountoulakis Konstantinos N

    2012-05-01

    Full Text Available Abstract Background The assessment of functioning and disability is an important part of the clinical evaluation, since it measures disease burden and reflects the effectiveness of therapeutic planning and interventions. The aim of the current study was to develop such a self-report instrument on the basis of a review of the literature, and compatible with the WHO approach. Material and methods The review of the literature led to the development of the Global Disability Scale (Glo.Di.S with 25 items assessing different aspects of disability. The study sample included 728 persons from vulnerable populations (homeless, jobless, very low income, single parent families etc.; (29.12% males and 70.88% females; aged 55.96 ± 15.22 years. The protocol included also the STAI and the CES-D. The statistical analysis included factor analysis item analysis and ANCOVA. Results The factor analysis revealed the presence of 4 factors explaining 71% of total variance (Everyday functioning, Social and interpersonal functioning, Severity and Mental disability. Chronbach’s alpha for the whole scale was 0.95 and for subscales were 0.74–0.94. Discussion The results of the current study suggest that the Glo.Di.S. has the potential to serve as a reliable and valid tool for assessing functioning and disability. Further research is needed to prove that it could be useful across countries, populations and diseases, and whether it provides data that are culturally meaningful and comparable. It can be used in surveys and in clinical research settings and it can generate information of use in evaluating health needs and the effectiveness of interventions to reduce disability and improve health.

  5. CUSUM control charts based on likelihood ratio for preliminary analysis

    Institute of Scientific and Technical Information of China (English)

    Yi DAI; Zhao-jun WANG; Chang-liang ZOU

    2007-01-01

    To detect and estimate a shift in either the mean and the deviation or both for the preliminary analysis, the statistical process control (SPC) tool, the control chart based on the likelihood ratio test (LRT), is the most popular method.Sullivan and woodall pointed out the test statistic lrt (n1, n2) is approximately distributed as x2 (2) as the sample size n, n1 and n2 are very large, and the value of n1 = 2, 3,..., n- 2 and that of n2 = n- n1.So it is inevitable that n1 or n2 is not large. In this paper the limit distribution of lrt(n1, n2) for fixed n1 or n2 is figured out, and the exactly analytic formulae for evaluating the expectation and the variance of the limit distribution are also obtained.In addition, the properties of the standardized likelihood ratio statistic slr(n1,n) are discussed in this paper. Although slr(n1, n) contains the most important information, slr(i, n)(i ≠ n1) also contains lots of information. The cumulative sum (CUSUM) control chart can obtain more information in this condition. So we propose two CUSUM control charts based on the likelihood ratio statistics for the preliminary analysis on the individual observations. One focuses on detecting the shifts in location in the historical data and the other is more general in detecting a shift in either the location and the scale or both.Moreover, the simulated results show that the proposed two control charts are, respectively, superior to their competitors not only in the detection of the sustained shifts but also in the detection of some other out-of-control situations considered in this paper.

  6. CUSUM control charts based on likelihood ratio for preliminary analysis

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    To detect and estimate a shift in either the mean and the deviation or both for the preliminary analysis, the statistical process control (SPC) tool, the control chart based on the likelihood ratio test (LRT), is the most popular method. Sullivan and woodall pointed out the test statistic lrt(n1, n2) is approximately distributed as x2(2) as the sample size n,n1 and n2 are very large, and the value of n1 = 2,3,..., n - 2 and that of n2 = n - n1. So it is inevitable that n1 or n2 is not large. In this paper the limit distribution of lrt(n1, n2) for fixed n1 or n2 is figured out, and the exactly analytic formulae for evaluating the expectation and the variance of the limit distribution are also obtained. In addition, the properties of the standardized likelihood ratio statistic slr(n1, n) are discussed in this paper. Although slr(n1, n) contains the most important information, slr(i, n)(i≠n1) also contains lots of information. The cumulative sum (CUSUM) control chart can obtain more information in this condition. So we propose two CUSUM control charts based on the likelihood ratio statistics for the preliminary analysis on the individual observations. One focuses on detecting the shifts in location in the historical data and the other is more general in detecting a shift in either the location and the scale or both. Moreover, the simulated results show that the proposed two control charts are, respectively, superior to their competitors not only in the detection of the sustained shifts but also in the detection of some other out-of-control situations considered in this paper.

  7. Global analysis of the immune response

    Science.gov (United States)

    Ribeiro, Leonardo C.; Dickman, Ronald; Bernardes, Américo T.

    2008-10-01

    The immune system may be seen as a complex system, characterized using tools developed in the study of such systems, for example, surface roughness and its associated Hurst exponent. We analyze densitometric (Panama blot) profiles of immune reactivity, to classify individuals into groups with similar roughness statistics. We focus on a population of individuals living in a region in which malaria endemic, as well as a control group from a disease-free region. Our analysis groups individuals according to the presence, or absence, of malaria symptoms and number of malaria manifestations. Applied to the Panama blot data, our method proves more effective at discriminating between groups than principal-components analysis or super-paramagnetic clustering. Our findings provide evidence that some phenomena observed in the immune system can be only understood from a global point of view. We observe similar tendencies between experimental immune profiles and those of artificial profiles, obtained from an immune network model. The statistical entropy of the experimental profiles is found to exhibit variations similar to those observed in the Hurst exponent.

  8. Crystallization and preliminary X-ray diffraction analysis of West Nile virus

    Energy Technology Data Exchange (ETDEWEB)

    Kaufmann, Barbel; Plevka, Pavel; Kuhn, Richard J.; Rossmann, Michael G. (Purdue)

    2010-05-25

    West Nile virus, a human pathogen, is closely related to other medically important flaviviruses of global impact such as dengue virus. The infectious virus was purified from cell culture using polyethylene glycol (PEG) precipitation and density-gradient centrifugation. Thin amorphously shaped crystals of the lipid-enveloped virus were grown in quartz capillaries equilibrated by vapor diffusion. Crystal diffraction extended at best to a resolution of about 25 {angstrom} using synchrotron radiation. A preliminary analysis of the diffraction images indicated that the crystals had unit-cell parameters a {approx_equal} b {approx_equal} 480 {angstrom}, {gamma} = 120{sup o}, suggesting a tight hexagonal packing of one virus particle per unit cell.

  9. Global resilience analysis of water distribution systems.

    Science.gov (United States)

    Diao, Kegong; Sweetapple, Chris; Farmani, Raziyeh; Fu, Guangtao; Ward, Sarah; Butler, David

    2016-12-01

    Evaluating and enhancing resilience in water infrastructure is a crucial step towards more sustainable urban water management. As a prerequisite to enhancing resilience, a detailed understanding is required of the inherent resilience of the underlying system. Differing from traditional risk analysis, here we propose a global resilience analysis (GRA) approach that shifts the objective from analysing multiple and unknown threats to analysing the more identifiable and measurable system responses to extreme conditions, i.e. potential failure modes. GRA aims to evaluate a system's resilience to a possible failure mode regardless of the causal threat(s) (known or unknown, external or internal). The method is applied to test the resilience of four water distribution systems (WDSs) with various features to three typical failure modes (pipe failure, excess demand, and substance intrusion). The study reveals GRA provides an overview of a water system's resilience to various failure modes. For each failure mode, it identifies the range of corresponding failure impacts and reveals extreme scenarios (e.g. the complete loss of water supply with only 5% pipe failure, or still meeting 80% of demand despite over 70% of pipes failing). GRA also reveals that increased resilience to one failure mode may decrease resilience to another and increasing system capacity may delay the system's recovery in some situations. It is also shown that selecting an appropriate level of detail for hydraulic models is of great importance in resilience analysis. The method can be used as a comprehensive diagnostic framework to evaluate a range of interventions for improving system resilience in future studies.

  10. Global Analysis of a Flexible Riser

    Institute of Scientific and Technical Information of China (English)

    Liping Sun; Bo Qi

    2011-01-01

    The mechanical performance of a flexible riser is more outstanding than other risers in violent environmental conditions.Based on the lumped mass method,a steep wave flexible riser configuration attached to a Floating Production Storage and Offloading(FPSO)has been applied to a global analysis in order to acquire the static and dynamic behavior of the flexible riser.The riser was divided into a series of straight massless line segments with a node at each end.Only the axial and torsional properties of the line were modeled,while the mass,weight,and buoyancy were all lumped to the nodes.Four different buoyancy module lengths have been made to demonstrate the importance of mode selection,so as to confirm the optimum buoyancy module length.The results in the sensitivity study show that the flexible riser is not very sensitive to the ocean current,and the buoyancy module can reduce the Von Mises stress and improve the mechanical performance of the flexible riser.Shorter buoyancy module length can reduce the riser effective tension in a specific range of the buoyancy module length when other parameters are constant,but it can also increase the maximum curvature of the riser.As a result,all kinds of the riser performances should be taken into account in order to select the most appropriate buoyancy module length.

  11. Global analysis of photosynthesis transcriptional regulatory networks.

    Science.gov (United States)

    Imam, Saheed; Noguera, Daniel R; Donohue, Timothy J

    2014-12-01

    Photosynthesis is a crucial biological process that depends on the interplay of many components. This work analyzed the gene targets for 4 transcription factors: FnrL, PrrA, CrpK and MppG (RSP_2888), which are known or predicted to control photosynthesis in Rhodobacter sphaeroides. Chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) identified 52 operons under direct control of FnrL, illustrating its regulatory role in photosynthesis, iron homeostasis, nitrogen metabolism and regulation of sRNA synthesis. Using global gene expression analysis combined with ChIP-seq, we mapped the regulons of PrrA, CrpK and MppG. PrrA regulates ∼34 operons encoding mainly photosynthesis and electron transport functions, while CrpK, a previously uncharacterized Crp-family protein, regulates genes involved in photosynthesis and maintenance of iron homeostasis. Furthermore, CrpK and FnrL share similar DNA binding determinants, possibly explaining our observation of the ability of CrpK to partially compensate for the growth defects of a ΔFnrL mutant. We show that the Rrf2 family protein, MppG, plays an important role in photopigment biosynthesis, as part of an incoherent feed-forward loop with PrrA. Our results reveal a previously unrealized, high degree of combinatorial regulation of photosynthetic genes and significant cross-talk between their transcriptional regulators, while illustrating previously unidentified links between photosynthesis and the maintenance of iron homeostasis.

  12. Preliminary analysis of distributed in situ soil moisture measurements

    Directory of Open Access Journals (Sweden)

    L. Brocca

    2005-01-01

    Full Text Available Surface soil moisture content is highly variable in both space and time. Remote sensing can provide an effective methodology for mapping surface moisture content over large areas but ground based measurements are required to test its reliability and to calibrate retrieval algorithms. Recently, we had the opportunity to design and perform an experiment aimed at jointly acquiring measurements of surface soil water content at various locations and remotely sensed hyperspectral data. The area selected for the experiment is located in central Umbria and it extends for 90km2. For the area, detailed lithological and multi-temporal landslide inventory maps were available. We identified eight plots where measurements of soil water content were made using a Time Domain Reflectometer (TDR. The plots range in size from 100m2 to 600m2, and cover a variety of topographic and morphological settings. The TDR measurements were conducted during four days, on 5 April, 15 April, 2 May and 3 May 2004. On 3 May the NERC airborne CASI 2 acquired the hyperspectral data. Preliminary analysis concerning the matching between the landslides and the soil moisture were reported. Statistical and geostatistical analysis investigating the spatial-temporal soil moisture distribution were performed. These results will be compared with the data of surface temperature obtained from the remotely sensed hyperspectral sensor.

  13. Modelling and analysis of global coal markets

    Energy Technology Data Exchange (ETDEWEB)

    Trueby, Johannes

    2013-01-17

    International Steam Coal Trade. In this paper, we analyse steam coal market equilibria in the years 2006 and 2008 by testing for two possible market structure scenarios: perfect competition and an oligopoly setup with major exporters competing in quantities. The assumed oligopoly scenario cannot explain market equilibria for any year. While we find that the competitive model simulates market equilibria well in 2006, the competitive model is not able to reproduce real market outcomes in 2008. The analysis shows that not all available supply capacity was utilised in 2008. We conclude that either unknown capacity bottlenecks or more sophisticated non-competitive strategies were the cause for the high prices in 2008. Chapter 4 builds upon the findings of the analysis in chapter 3 and adds a more detailed representation of domestic markets. The corresponding essay is titled Nations as Strategic Players in Global Commodity Markets: Evidence from World Coal Trade. In this chapter we explore the hypothesis that export policies and trade patterns of national players in the steam coal market are consistent with non-competitive market behaviour. We test this hypothesis by developing a static equilibrium model which is able to model coal producing nations as strategic players. We explicitly account for integrated seaborne trade and domestic markets. The global steam coal market is simulated under several imperfect market structure setups. We find that trade and prices of a China - Indonesia duopoly fits the real market outcome best and that real Chinese export quotas in 2008 were consistent with simulated exports under a Cournot-Nash strategy. Chapter 5 looks at the long-term effect of Chinese energy system planning decisions. The time horizon is 2006 to 2030. The analysis in this chapter combines a dynamic equilibrium model with the scenario analysis technique. The corresponding essay is titled Coal Lumps vs. Electrons: How Do Chinese Bulk Energy Transport Decisions Affect the Global

  14. Electroweak Precision Data - Global Higgs Analysis

    CERN Document Server

    Grünewald, M W

    2003-01-01

    The status of published and preliminary precision electroweak measurements as of winter 2002/03 is presented. The new results on the mass of the W boson as measured at LEP-2 and on atomic parity violation in Caesium are included. The experimental results are compared with the predictions of the minimal Standard Model and are used to constrain its parameters, including the mass of the Higgs boson. The agreement between measurements and expectations from theory is discussed.

  15. State of the Climate - Global Analysis

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The State of the Climate is a collection of periodic summaries recapping climate-related occurrences on both a global and national scale. The State of the Climate...

  16. Grid-connected ICES: preliminary feasibility analysis and evaluation. Volume 2. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1977-06-30

    The HEAL Complex in New Orleans will serve as a Demonstration Community for which the ICES Demonstration System will be designed. The complex is a group of hospitals, clinics, research facilities, and medical educational facilities. The five tasks reported on are: preliminary energy analysis; preliminary institutional assessment; conceptual design; firming-up of commitments; and detailed work management plan.

  17. Purification, crystallization and preliminary X-ray analysis of struthiocalcin 1 from ostrich (Struthio camelus) eggshell

    Energy Technology Data Exchange (ETDEWEB)

    Reyes-Grajeda, Juan Pablo [Unidad de Proteómica Médica, Instituto Nacional de Medicina Genómica, Mexico City (Mexico); Marín-García, Liliana [Instituto de Química, Universidad Nacional Autónoma de México (Mexico); Stojanoff, Vivian [Brookhaven National Laboratories, NSLS, Upton, New York (United States); Moreno, Abel, E-mail: carcamo@servidor.unam.mx [Instituto de Química, Universidad Nacional Autónoma de México (Mexico); Unidad de Proteómica Médica, Instituto Nacional de Medicina Genómica, Mexico City (Mexico)

    2007-11-01

    The purification, crystallization and preliminary X-ray diffraction data of the protein struthiocalcin 1 isolated from ostrich eggshell are reported. The purification, crystallization and preliminary X-ray analysis of struthiocalcin 1 (SCA-1), a protein obtained from the intramineral part of ostrich (Struthio camelus) eggshell, is reported.

  18. Investigation of Sorption and Diffusion Mechanisms, and Preliminary Economic Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Bhave, Ramesh R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Jubin, Robert Thomas [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Spencer, Barry B. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Nair, Sankar [Georgia Inst. of Technology, Atlanta, GA (United States)

    2017-02-01

    This report describes the synthesis and evaluation of molecular sieve zeolite membranes to separate and concentrate tritiated water (HTO) from dilute HTO-bearing aqueous streams. Several monovalent and divalent cation exchanged silico alumino phosphate (SAPO-34) molecular sieve zeolite membranes were synthesized on disk supports and characterized with gas and vapor permeation measurements. The pervaporation process performance was evaluated for the separation and concentration of tritiated water. Experiments were performed using tritiated water feed solution containing tritium at the high end of the range (1 mCi/mL) anticipated in a nuclear fuel processing system that includes both acid and water streams recycling. The tritium concentration was about 0.1 ppm. The permeate was recovered under vacuum. The HTO/H2O selectivity and separation factor calculated from the measured tritium concentrations ranged from 0.99 to 1.23, and 0.83-0.98, respectively. Although the membrane performance for HTO separation was lower than expected, several encouraging observations including molecular sieving and high vapor permeance are reported. Additionally, several new approaches are proposed, such as tuning the sorption and diffusion properties offered by small pore LTA zeolite materials, and cation exchanged aluminosilicates with high metal loading. It is hypothesized that substantially improved preferential transport of tritium (HTO) resulting in a more concentrated permeate can be achieved. Preliminary economic analysis for the membrane-based process to concentrate tritiated water is also discussed.

  19. Crystallization and preliminary crystallographic analysis of recombinant human galectin-1

    Energy Technology Data Exchange (ETDEWEB)

    Scott, Stacy A. [Institute for Glycomics, Gold Coast Campus, Griffith University, Queensland 4222 (Australia); Scott, Ken [School of Biological Sciences, University of Auckland, Auckland (New Zealand); Blanchard, Helen, E-mail: h.blanchard@griffith.edu.au [Institute for Glycomics, Gold Coast Campus, Griffith University, Queensland 4222 (Australia)

    2007-11-01

    Human galectin-1 has been cloned, expressed in E. coli, purified and crystallized in the presence of both lactose (ligand) and β-mercaptoethanol under six different conditions. The X-ray diffraction data obtained have enabled the assignment of unit-cell parameters for two novel crystal forms of human galectin-1. Galectin-1 is considered to be a regulator protein as it is ubiquitously expressed throughout the adult body and is responsible for a broad range of cellular regulatory functions. Interest in galectin-1 from a drug-design perspective is founded on evidence of its overexpression by many cancers and its immunomodulatory properties. The development of galectin-1-specific inhibitors is a rational approach to the fight against cancer because although galectin-1 induces a plethora of effects, null mice appear normal. X-ray crystallographic structure determination will aid the structure-based design of galectin-1 inhibitors. Here, the crystallization and preliminary diffraction analysis of human galectin-1 crystals generated under six different conditions is reported. X-ray diffraction data enabled the assignment of unit-cell parameters for crystals grown under two conditions, one belongs to a tetragonal crystal system and the other was determined as monoclinic P2{sub 1}, representing two new crystal forms of human galectin-1.

  20. Preliminary radiation criteria and nuclear analysis for ETF

    Energy Technology Data Exchange (ETDEWEB)

    Engholm, B.A.

    1980-09-01

    Preliminary biological and materials radiation dose criteria for the Engineering Test Facility are described and tabulated. In keeping with the ETF Mission Statement, a key biological dose criterion is a 24-hour shutdown dose rate of 2 mrem/hr on the surface of the outboard bulk shield. Materials dose criteria, which primarily govern the inboard shield design, include 10/sup 9/ rads exposure limit to epoxy insulation, 3 x 10/sup -4/ dpa damage to the TF coil copper stabilizer, and a total nuclear heating rate of 5 kW in the inboard TF coils. Nuclear analysis performed during FY 80 was directed primarily at the inboard and outboard bulk shielding, and at radiation streaming in the neutral beam drift ducts. Inboard and outboard shield thicknesses to achieve the biological and materials radiation criteria are 75 cm inboard and 125 cm outboard, the configuration consisting of alternating layers of stainless steel and borated water. The outboard shield also includes a 5 cm layer of lead. NBI duct streaming analyses performed by ORNL and LASL will play a key role in the design of the duct and NBI shielding in FY 81. The NBI aluminum cryopanel nuclear heating rate during the heating cycle is about 1 milliwatt/cm/sup 3/, which is far less than the permissible limit.

  1. Preliminary analysis of aerial hyperspectral data on shallow lacustrine waters

    Science.gov (United States)

    Bianchi, Remo; Castagnoli, A.; Cavalli, Rosa M.; Marino, Carlo M.; Pignatti, Stefano; Zilioli, Eugenio

    1995-11-01

    The availability of MIVIS hyperspectral data, deriving from an aerial survey recently performed over a test-site in Lake Garda, Italy, gave the possibility of a preliminary new insight in the field of specific applications of remote sensing to shallow water analysis. The spectroradiometers in the visible and in the thermal infrared were explored in particular, accessing to helpful information for the detection of bio-physical indicators of water quality, either related to the surface/sub-surface of waters or to the bottom of the lake, since the study area presents very shallow waters, never exceeding a 6-meter depth in any case. Primary interest was the detection of man-induced activities along the margins, like sewage effect and sedimentary structure in the bottom or algal bloom. Secondly, a correlation between absorbivity coefficients in the visible bands and bathimetric contour lines in the proximity of the marginal zone of the lake was accomplished, by means of two indicative spectroradiometric transects.

  2. Global review of open access risk assessment software packages valid for global or continental scale analysis

    Science.gov (United States)

    Daniell, James; Simpson, Alanna; Gunasekara, Rashmin; Baca, Abigail; Schaefer, Andreas; Ishizawa, Oscar; Murnane, Rick; Tijssen, Annegien; Deparday, Vivien; Forni, Marc; Himmelfarb, Anne; Leder, Jan

    2015-04-01

    Over the past few decades, a plethora of open access software packages for the calculation of earthquake, volcanic, tsunami, storm surge, wind and flood have been produced globally. As part of the World Bank GFDRR Review released at the Understanding Risk 2014 Conference, over 80 such open access risk assessment software packages were examined. Commercial software was not considered in the evaluation. A preliminary analysis was used to determine whether the 80 models were currently supported and if they were open access. This process was used to select a subset of 31 models that include 8 earthquake models, 4 cyclone models, 11 flood models, and 8 storm surge/tsunami models for more detailed analysis. By using multi-criteria analysis (MCDA) and simple descriptions of the software uses, the review allows users to select a few relevant software packages for their own testing and development. The detailed analysis evaluated the models on the basis of over 100 criteria and provides a synopsis of available open access natural hazard risk modelling tools. In addition, volcano software packages have since been added making the compendium of risk software tools in excess of 100. There has been a huge increase in the quality and availability of open access/source software over the past few years. For example, private entities such as Deltares now have an open source policy regarding some flood models (NGHS). In addition, leaders in developing risk models in the public sector, such as Geoscience Australia (EQRM, TCRM, TsuDAT, AnuGA) or CAPRA (ERN-Flood, Hurricane, CRISIS2007 etc.), are launching and/or helping many other initiatives. As we achieve greater interoperability between modelling tools, we will also achieve a future wherein different open source and open access modelling tools will be increasingly connected and adapted towards unified multi-risk model platforms and highly customised solutions. It was seen that many software tools could be improved by enabling user

  3. Globalization

    DEFF Research Database (Denmark)

    Plum, Maja

    Globalization is often referred to as external to education - a state of affair facing the modern curriculum with numerous challenges. In this paper it is examined as internal to curriculum; analysed as a problematization in a Foucaultian sense. That is, as a complex of attentions, worries, ways...... of reasoning, producing curricular variables. The analysis is made through an example of early childhood curriculum in Danish Pre-school, and the way the curricular variable of the pre-school child comes into being through globalization as a problematization, carried forth by the comparative practices of PISA...

  4. Is globalization healthy: a statistical indicator analysis of the impacts of globalization on health.

    Science.gov (United States)

    Martens, Pim; Akin, Su-Mia; Maud, Huynen; Mohsin, Raza

    2010-09-17

    It is clear that globalization is something more than a purely economic phenomenon manifesting itself on a global scale. Among the visible manifestations of globalization are the greater international movement of goods and services, financial capital, information and people. In addition, there are technological developments, more transboundary cultural exchanges, facilitated by the freer trade of more differentiated products as well as by tourism and immigration, changes in the political landscape and ecological consequences. In this paper, we link the Maastricht Globalization Index with health indicators to analyse if more globalized countries are doing better in terms of infant mortality rate, under-five mortality rate, and adult mortality rate. The results indicate a positive association between a high level of globalization and low mortality rates. In view of the arguments that globalization provides winners and losers, and might be seen as a disequalizing process, we should perhaps be careful in interpreting the observed positive association as simple evidence that globalization is mostly good for our health. It is our hope that a further analysis of health impacts of globalization may help in adjusting and optimising the process of globalization on every level in the direction of a sustainable and healthy development for all.

  5. Is globalization healthy: a statistical indicator analysis of the impacts of globalization on health

    Directory of Open Access Journals (Sweden)

    Martens Pim

    2010-09-01

    Full Text Available Abstract It is clear that globalization is something more than a purely economic phenomenon manifesting itself on a global scale. Among the visible manifestations of globalization are the greater international movement of goods and services, financial capital, information and people. In addition, there are technological developments, more transboundary cultural exchanges, facilitated by the freer trade of more differentiated products as well as by tourism and immigration, changes in the political landscape and ecological consequences. In this paper, we link the Maastricht Globalization Index with health indicators to analyse if more globalized countries are doing better in terms of infant mortality rate, under-five mortality rate, and adult mortality rate. The results indicate a positive association between a high level of globalization and low mortality rates. In view of the arguments that globalization provides winners and losers, and might be seen as a disequalizing process, we should perhaps be careful in interpreting the observed positive association as simple evidence that globalization is mostly good for our health. It is our hope that a further analysis of health impacts of globalization may help in adjusting and optimising the process of globalization on every level in the direction of a sustainable and healthy development for all.

  6. Is globalization healthy: a statistical indicator analysis of the impacts of globalization on health

    Science.gov (United States)

    2010-01-01

    It is clear that globalization is something more than a purely economic phenomenon manifesting itself on a global scale. Among the visible manifestations of globalization are the greater international movement of goods and services, financial capital, information and people. In addition, there are technological developments, more transboundary cultural exchanges, facilitated by the freer trade of more differentiated products as well as by tourism and immigration, changes in the political landscape and ecological consequences. In this paper, we link the Maastricht Globalization Index with health indicators to analyse if more globalized countries are doing better in terms of infant mortality rate, under-five mortality rate, and adult mortality rate. The results indicate a positive association between a high level of globalization and low mortality rates. In view of the arguments that globalization provides winners and losers, and might be seen as a disequalizing process, we should perhaps be careful in interpreting the observed positive association as simple evidence that globalization is mostly good for our health. It is our hope that a further analysis of health impacts of globalization may help in adjusting and optimising the process of globalization on every level in the direction of a sustainable and healthy development for all. PMID:20849605

  7. Global Analysis of a Planetary Gear Train

    Directory of Open Access Journals (Sweden)

    Tongjie Li

    2014-01-01

    Full Text Available By using the Poincaré-like cell-to-cell mapping method and shooting method, the global characteristics of a planetary gear train are studied based on the torsional vibration model with errors of transmission, time-varying meshing stiffness, and multiple gear backlashes. The study results reveal that the planetary with a certain set of parameters has four coexisting periodic orbits, which are P-1, P-2, P-4, and P-8, respectively. P-1 and P-2 motions are not of long-term stability, P-8 motion is of local stability, and P-4 motion is of global stability. Shooting method does not have the capacity of searching coexisting periodic orbits in a global scope, and it is easy to omit some periodic orbits which are far away from the main gropes of periodic orbits.

  8. Preliminary Analysis of Remote Monitoring & Robotic Concepts for Performance Confirmation

    Energy Technology Data Exchange (ETDEWEB)

    D.A. McAffee

    1997-02-18

    ) Identify and discuss the main Performance Confirmation monitoring needs and requirements during the post-emplacement preclosure period. This includes radiological, non-radiological, host rock, and infrastructure performance monitoring needs. It also includes monitoring for possible off-normal events. (Presented in Section 7.3). (3) Identify general approaches and methods for obtaining performance information from within the emplacement drifts for Performance Confirmation. (Presented in Section 7.4) (4)Review and discuss available technologies and design strategies that may permit the use of remotely operated systems within the hostile thermal and radiation environment expected within the emplacement drifts. (Presented in Section 7.5). (5) Based on Performance Confirmation monitoring needs and available technologies, identify potential application areas for remote systems and robotics for post-emplacement preclosure Performance Confirmation activities (Presented in Section 7.6). (6) Develop preliminary remote monitoring and robotic concepts for post-emplacement, preclosure Performance Confirmation activities. (Presented in Section 7.7) This analysis is being performed very early in the systems engineering cycle, even as issues related to the Performance Confirmation program planning phase are being formulated and while the associated needs, constraints and objectives are yet to be fully determined and defined. This analysis is part of an issue formulation effort and is primarily concerned with identification and description of key issues related to remotely monitoring repository performance for Performance Confirmation. One of the purposes of this analysis is to provide an early investigation of potential design challenges that may have a high impact on future design concepts. This analysis can be used to guide future concept development and help access what is feasible and achievable by application of remote systems technology. Future design and systems engineering

  9. A Preliminary Tsunami vulnerability analysis for Bakirkoy district in Istanbul

    Science.gov (United States)

    Tufekci, Duygu; Lutfi Suzen, M.; Cevdet Yalciner, Ahmet; Zaytsev, Andrey

    2016-04-01

    Resilience of coastal utilities after earthquakes and tsunamis has major importance for efficient and proper rescue and recovery operations soon after the disasters. Vulnerability assessment of coastal areas under extreme events has major importance for preparedness and development of mitigation strategies. The Sea of Marmara has experienced numerous earthquakes as well as associated tsunamis. There are variety of coastal facilities such as ports, small craft harbors, and terminals for maritime transportation, water front roads and business centers mainly at North Coast of Marmara Sea in megacity Istanbul. A detailed vulnerability analysis for Yenikapi region and a detailed resilience analysis for Haydarpasa port in Istanbul have been studied in previously by Cankaya et al., (2015) and Aytore et al., (2015) in SATREPS project. In this study, the methodology of vulnerability analysis under tsunami attack given in Cankaya et al., (2015) is modified and applied to Bakirkoy district of Istanbul. Bakirkoy district is located at western part of Istanbul and faces to the North Coast of Marmara Sea from 28.77oE to 28.89oE. High resolution spatial dataset of Istanbul Metropolitan Municipality (IMM) is used and analyzed. The bathymetry and topography database and the spatial dataset containing all buildings/structures/infrastructures in the district are collated and utilized for tsunami numerical modeling and following vulnerability analysis. The tsunami parameters from deterministically defined worst case scenarios are computed from the simulations using tsunami numerical model NAMI DANCE. The vulnerability assessment parameters in the district according to vulnerability and resilience are defined; and scored by implementation of a GIS based TVA with appropriate MCDA methods. The risk level is computed using tsunami intensity (level of flow depth from simulations) and TVA results at every location in Bakirkoy district. The preliminary results are presented and discussed

  10. Toward Global Content Analysis and Media Criticism.

    Science.gov (United States)

    Nordenstreng, Kaarle

    1995-01-01

    Presents the background, rationale, and implementation prospects for an international system of monitoring media coverage of global problems such as peace and war, human rights, and the environment. Outlines the monitoring project carried out in January 1995 concerning the representation and portrayal of women in news media. (SR)

  11. Land concentration and land grabbing in Europe: a preliminary analysis

    NARCIS (Netherlands)

    Ploeg, van der J.D.; Franco, J.; Saturnino, M.B.

    2015-01-01

    This article offers three insights. First, the renewed global land rush is indeed global: it occurs in the Global North too. Second, the ongoing trend of (generic) land concentration is just as problematic as land grabbing. Third, political processes involving actors at various sites and levels of t

  12. Preliminary Core Analysis of a Micro Modular Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Jo, Chang Keun; Chang, Jongwa [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Venneri, Francesco [Ultra Safe Nuclear Corporation, Los Alamos (United States); Hawari, Ayman [NC State Univ., Raleigh (United States)

    2014-05-15

    The Micro Modular Reactor (MMR) will be 'melt-down proof'(MDP) under all circumstances, including the complete loss of coolant, and will be easily transportable and retrievable, and suitable for use with very little site preparation and Balance of Plant (BOP) requirements for a variety of applications, from power generation and process heat applications in remote areas to grid-unattached locations, including ship propulsion. The Micro Modular Reactor design proposed in this paper has 3 meter diameter core (2 meter active core) which is suitable for 'factory manufactured' and has few tens year of service life for remote deployment. We confirmed the feasibility of long term service life by a preliminary neutronic analysis in terms of the excess reactivity, the temperature feedback coefficient, and the control margins. We are able to achieve a reasonably long core life time of 5 ∼ 10 years under typical thermal hydraulic condition of a helium cooled reactor. However, on a situation where longer service period and safety is important, we can reduce the power density to the level of typical pebble bed reactor. In this case we can design 10 MWt MMR with core diameter for 10 ∼ 40 years core life time without much loss in the economics. Several burnable poisons are studied and it is found that erbia mixed in the compact matrix seems reasonably good poison. The temperature feedback coefficients were remaining negative during lifetime. Drum type control rods at reflector region and few control rods inside core region are sufficient to control the reactivity during operation and to achieve safe cold shutdown state.

  13. Meta-analysis and its application in global change research

    Institute of Scientific and Technical Information of China (English)

    LEI XiangDong; PENG ChangHui; TIAN DaLun; SUN JianFeng

    2007-01-01

    Meta-analysis is a quantitative synthetic research method that statistically integrates results from individual studies to find common trends and differences. With increasing concern over global change, meta-analysis has been rapidly adopted in global change research. Here, we introduce the methodologies, advantages and disadvantages of meta-analysis, and review its application in global climate change research, including the responses of ecosystems to global warming and rising CO2 and O3 concentrations, the effects of land use and management on climate change and the effects of disturbances on biogeochemistry cycles of ecosystem. Despite limitation and potential misapplication, meta-analysis has been demonstrated to be a much better tool than traditional narrative review in synthesizing results from multiple studies. Several methodological developments for research synthesis have not yet been widely used in global climate change researches such as cumulative meta-analysis and sensitivity analysis. It is necessary to update the results of meta-analysis on a given topic at regular intervals by including newly published studies. Emphasis should be put on multi-factor interaction and long-term experiments. There is great potential to apply meta-analysis to global climate change research in China because research and observation networks have been established (e.g. ChinaFlux and CERN), which create the need for combining these data and results to provide support for governments' decision making on climate change. It is expected that meta-analysis will be widely adopted in future climate change research.

  14. The Organic Food Market and Marketing Initiatives in Europe: a Preliminary Analysis

    DEFF Research Database (Denmark)

    Kristensen, Niels Heine; Nielsen, Thorkild; Bruselius-Jensen, Maria Louisa

    2003-01-01

    Kristensen NH, Nielsen T, Bruselius-Jensen M, Scheperlen-Bøgh P, Beckie M, Foster C, Midmore P, Padel S (2002): The Organic Food Market and Marketing Initiatives in Europe: a Preliminary Analysis. Final Report to the EU Commission......Kristensen NH, Nielsen T, Bruselius-Jensen M, Scheperlen-Bøgh P, Beckie M, Foster C, Midmore P, Padel S (2002): The Organic Food Market and Marketing Initiatives in Europe: a Preliminary Analysis. Final Report to the EU Commission...

  15. Global Analysis of Aerosol Properties Above Clouds

    Science.gov (United States)

    Waquet, F.; Peers, F.; Ducos, F.; Goloub, P.; Platnick, S. E.; Riedi, J.; Tanre, D.; Thieuleux, F.

    2013-01-01

    The seasonal and spatial varability of Aerosol Above Cloud (AAC) properties are derived from passive satellite data for the year 2008. A significant amount of aerosols are transported above liquid water clouds on the global scale. For particles in the fine mode (i.e., radius smaller than 0.3 m), including both clear sky and AAC retrievals increases the global mean aerosol optical thickness by 25(+/- 6%). The two main regions with man-made AAC are the tropical Southeast Atlantic, for biomass burning aerosols, and the North Pacific, mainly for pollutants. Man-made AAC are also detected over the Arctic during the spring. Mineral dust particles are detected above clouds within the so-called dust belt region (5-40 N). AAC may cause a warming effect and bias the retrieval of the cloud properties. This study will then help to better quantify the impacts of aerosols on clouds and climate.

  16. Preliminary study on washability and composition analysis of highsulfur coal in some mining areas in Guizhou

    Institute of Scientific and Technical Information of China (English)

    QIU Yue-qin; MAO Song; ZHANG Qin; TIAN Ye; LIU Zhi-hong

    2011-01-01

    Preliminary sink-float experiments on high-sulfur coal was done in some mining areas and carried on elementary analysis, industrial analysis, and ashcontent analysis. Through the experiments, definite middlings, and gangue, the phase analysis of sulfur was carried on, by which a good understanding of sulfur characters in raw coal was achieved.

  17. Preliminary Evidence for the Amplification of Global Warming in Shallow, Intertidal Estuarine Waters.

    Science.gov (United States)

    Oczkowski, Autumn; McKinney, Richard; Ayvazian, Suzanne; Hanson, Alana; Wigand, Cathleen; Markham, Erin

    2015-01-01

    Over the past 50 years, mean annual water temperature in northeastern U.S. estuaries has increased by approximately 1.2°C, with most of the warming recorded in the winter and early spring. A recent survey and synthesis of data from four locations in Southern Rhode Island has led us to hypothesize that this warming may be amplified in the shallow (<1 m), nearshore portions of these estuaries. While intertidal areas are not typically selected as locations for long-term monitoring, we compiled data from published literature, theses, and reports that suggest that enhanced warming may be occurring, perhaps at rates three times higher than deeper estuarine waters. Warmer spring waters may be one of the factors influencing biota residing in intertidal regions both in general as well as at our specific sites. We observed greater abundance of fish, and size of Menidia sp., in recent (2010-2012) seine surveys compared to similar collections in 1962. While any linkages are speculative and data are preliminary, taken together they suggest that shallow intertidal portions of estuaries may be important places to look for the effects of climate change.

  18. Preliminary Evidence for the Amplification of Global Warming in Shallow, Intertidal Estuarine Waters.

    Directory of Open Access Journals (Sweden)

    Autumn Oczkowski

    Full Text Available Over the past 50 years, mean annual water temperature in northeastern U.S. estuaries has increased by approximately 1.2°C, with most of the warming recorded in the winter and early spring. A recent survey and synthesis of data from four locations in Southern Rhode Island has led us to hypothesize that this warming may be amplified in the shallow (<1 m, nearshore portions of these estuaries. While intertidal areas are not typically selected as locations for long-term monitoring, we compiled data from published literature, theses, and reports that suggest that enhanced warming may be occurring, perhaps at rates three times higher than deeper estuarine waters. Warmer spring waters may be one of the factors influencing biota residing in intertidal regions both in general as well as at our specific sites. We observed greater abundance of fish, and size of Menidia sp., in recent (2010-2012 seine surveys compared to similar collections in 1962. While any linkages are speculative and data are preliminary, taken together they suggest that shallow intertidal portions of estuaries may be important places to look for the effects of climate change.

  19. Cusum charts for preliminary analysis of individual observations

    NARCIS (Netherlands)

    A.J. Koning (Alex); R.J.M.M. Does (Ronald)

    1997-01-01

    textabstractA preliminary Cusum chart based on individual observations is developed from the uniformly most powerful test for the detection of linear trends. This Cusum chart is compared with several of its competitors which are based on the likelihood ratio test and on transformations of standardiz

  20. "Competing Conceptions of Globalization" Revisited: Relocating the Tension between World-Systems Analysis and Globalization Analysis

    Science.gov (United States)

    Clayton, Thomas

    2004-01-01

    In recent years, many scholars have become fascinated by a contemporary, multidimensional process that has come to be known as "globalization." Globalization originally described economic developments at the world level. More specifically, scholars invoked the concept in reference to the process of global economic integration and the seemingly…

  1. Global analysis theory of climate system and its applications

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    The idea and main theoretical results of the global analysis theory of climate system are briefly summarized in this paper. A theorem on the global behavior of climate system is given, i.e. there exists a global attractor in the dynamical equations of climate, any state of climate system will be evolved into the global attractor as time increases, indicating the nonlinear adjustment process of climate system to external forcing. The different effects of external forcing, dissipation and nonlinearity on the long-term behavior of solutions are pointed out, and some main applications of the global analysis theory are also introduced. Especially, three applications, the adjustment and evolution processes of climate, the principle of numerical model design and the optimally numerical integration, are discussed.

  2. Global Analysis of a Planetary Gear Train

    OpenAIRE

    Tongjie Li; Rupeng Zhu

    2014-01-01

    By using the Poincaré-like cell-to-cell mapping method and shooting method, the global characteristics of a planetary gear train are studied based on the torsional vibration model with errors of transmission, time-varying meshing stiffness, and multiple gear backlashes. The study results reveal that the planetary with a certain set of parameters has four coexisting periodic orbits, which are P-1, P-2, P-4, and P-8, respectively. P-1 and P-2 motions are not of long-term stability, P-8 motion ...

  3. Community syndicalism for the United States: preliminary observations on law and globalization in democratic production

    Directory of Open Access Journals (Sweden)

    Kenneth M. Casebeer

    2012-05-01

    Full Text Available The Great Recession resulting from the globalization of Finance Capitalism created two structural labor crises for developed economies: 1 The channeling of substantial investment into non-productive, paper commodities, reducing growth of production for use and therefore reducing available aggregate job creation; and 2 The continued exportation of industrial jobs to other lower cost jurisdictions, and outsourcing, automation, just-in-time production, and speed-ups associated with global supply chains. As a result, local communities and regional populations have destabilized and even collapsed with attendant social problems. One possible response is Community Syndicalism – local community finance and operating credit for industrial production combined with democratic worker ownership and control of production. The result would increase investment directly for production, retain jobs in existing population centers, promote job skilling, and retain tax bases for local services and income supporting local businesses, at the same time increasing support for authentic political democracy by rendering the exploitive ideology of the Public/Private distinction superfluous. Slowing job exportation may reduce the global race to the bottom of labor standards and differential wage rates reducing the return to producers of value and increasing the skew of income distribution undermining social wages and welfare worldwide. Community Syndicalism can serve as moral goal in an alternative production model focusing incentives on long term stability of jobs and community economic base. La Gran Recesión que ha traído la globalización del capitalismo financiero ha dado lugar a dos crisis laborales estructurales en las economías desarrolladas: 1 El destino principal de la inversión hacia bienes no productivos, reduciendo la producción de bienes de consumo, y reduciendo también las posibilidades de creación de puestos de trabajo, y 2 el traslado de puestos de

  4. A Preliminary Analysis of Precipitation Properties and Processes during NASA GPM IFloodS

    Science.gov (United States)

    Carey, Lawrence; Gatlin, Patrick; Petersen, Walt; Wingo, Matt; Lang, Timothy; Wolff, Dave

    2014-01-01

    The Iowa Flood Studies (IFloodS) is a NASA Global Precipitation Measurement (GPM) ground measurement campaign, which took place in eastern Iowa from May 1 to June 15, 2013. The goals of the field campaign were to collect detailed measurements of surface precipitation using ground instruments and advanced weather radars while simultaneously collecting data from satellites passing overhead. Data collected by the radars and other ground instruments, such as disdrometers and rain gauges, will be used to characterize precipitation properties throughout the vertical column, including the precipitation type (e.g., rain, graupel, hail, aggregates, ice crystals), precipitation amounts (e.g., rain rate), and the size and shape of raindrops. The impact of physical processes, such as aggregation, melting, breakup and coalescence on the measured liquid and ice precipitation properties will be investigated. These ground observations will ultimately be used to improve rainfall estimates from satellites and in particular the algorithms that interpret raw data for the upcoming GPM mission's Core Observatory satellite, which launches in 2014. The various precipitation data collected will eventually be used as input to flood forecasting models in an effort to improve capabilities and test the utility and limitations of satellite precipitation data for flood forecasting. In this preliminary study, the focus will be on analysis of NASA NPOL (S-band, polarimetric) radar (e.g., radar reflectivity, differential reflectivity, differential phase, correlation coefficient) and NASA 2D Video Disdrometers (2DVDs) measurements. Quality control and processing of the radar and disdrometer data sets will be outlined. In analyzing preliminary cases, particular emphasis will be placed on 1) documenting the evolution of the rain drop size distribution (DSD) as a function of column melting processes and 2) assessing the impact of range on ground-based polarimetric radar estimates of DSD properties.

  5. Global coupled equations for dynamic analysis of planishing mill

    Institute of Scientific and Technical Information of China (English)

    蔡敢为; 钟掘

    2003-01-01

    The dynamic properties of rolling mill are significantly influenced by many coupling factors. Accordingto the coupled mechanical and electric dynamics theory, the global coupled equations for the dynamic analysis ofplanishing mill CM04 of Shanghai Baosteel Group Corporation were derived, by using finite element methods. Theseelasto-dynamic equations establish the coupling relations among the stand vibration system, torsional vibration sys-tem, driving motors, etc. It provides theoretical basis to a certain extent for globally dynamic simulation, analysis ofstability of motion, prediction of abnormal operating mode, globally optimum design and control, etc.

  6. Preliminary design of a small air loop for system analysis and validation of Cathare code

    Energy Technology Data Exchange (ETDEWEB)

    Marchand, M.; Saez, M.; Tauveron, N.; Tenchine, D.; Germain, T.; Geffraye, G.; Ruby, G.P. [CEA Grenoble (DEN/DER/SSTH), 38 (France)

    2007-07-01

    The French Atomic Energy Commission (Cea) is carrying on the design of a Small Air Loop for System Analysis (SALSA), devoted to the study of gas cooled nuclear reactors behaviour in normal and incidental/accidental operating conditions. The reduced size of the SALSA components compared to a full-scale reactor and air as gaseous coolant instead of Helium will allow an easy management of the loop. The main purpose of SALSA will be the validation of the associated thermal hydraulic safety simulation codes, like CATHARE. The main goal of this paper is to present the methodology used to define the characteristics of the loop. In a first step, the study has been focused on a direct-cycle system for the SALSA loop with few global constraints using a similarity analysis to support the definition and design of the loop. Similarity requirements have been evaluated to determine the scale factors which have to be applied to the SALSA loop components. The preliminary conceptual design of the SALSA plant with a definition of each component has then be carried out. The whole plant has been modelled using the CATHARE code. Calculations of the SALSA steady-state in nominal conditions and of different plant transients in direct-cycle have been made. The first system results obtained on the global behaviour of the loop confirm that SALSA can be representative of a Gas-Cooled nuclear reactor with some minor design modifications. In a second step, the current prospects focus on the SALSA loop capability to reproduce correctly the heat transfer occurring in specific incidental situations. Heat decay removal by natural convection is a crucial point of interest. The first results show that the behaviour and the efficiency of the loop are strongly influenced by the definition of the main parameters for each component. A complete definition of SALSA is under progress. (authors)

  7. Sammon mapping for preliminary analysis in Hyperspectral Imagery

    Directory of Open Access Journals (Sweden)

    Nicolae APOSTOLESCU

    2016-03-01

    Full Text Available The main goal of this paper is to present the implementation of the Sammon algorithm developed for finding N points in a lower m-dimensional subspace, where the original points are from a high n-dimensional space. This mapping is done so interpoints Euclidian distances in m-space correspond to the distances measured in the n-dimensional space. This method known as non-linear projection method or multidimensional scaling (MDS aims to preserve the global properties of points. The method is based on the idea of transforming the original, n-dimensional input space into a reduced, m-dimensional one, where mAnalysis (PCA may be applied as a pre-processing procedure for starting, in order to obtain the N points in the lower subspace. The algorithm was tested on hyperspectral data with spectra of various lengths. Depending of the size of the input data (number of points, the number of learning iterations and computational facilities available, Sammon mapping might be computationally expensive.

  8. A global mean dynamic topography and ocean circulation estimation using a preliminary GOCE gravity model

    DEFF Research Database (Denmark)

    Knudsen, Per; Bingham, R.; Andersen, Ole Baltazar

    2011-01-01

    The Gravity and steady-state Ocean Circulation Explorer (GOCE) satellite mission measures Earth’s gravity field with an unprecedented accuracy at short spatial scales. In doing so, it promises to significantly advance our ability to determine the ocean’s general circulation. In this study......, an initial gravity model from GOCE, based on just 2 months of data, is combined with the recent DTU10MSS mean sea surface to construct a global mean dynamic topography (MDT) model. The GOCE MDT clearly displays the gross features of the ocean’s steady-state circulation. More significantly, the improved...... gravity model provided by the GOCE mission has enhanced the resolution and sharpened the boundaries of those features compared with earlier satellite only solutions. Calculation of the geostrophic surface currents from the MDT reveals improvements for all of the ocean’s major current systems. In the North...

  9. Water Grabbing analysis at global scale

    Science.gov (United States)

    Rulli, M.; Saviori, A.; D'Odorico, P.

    2012-12-01

    "Land grabbing" is the acquisition of agricultural land by foreign governments and corporations, a phenomenon that has greatly intensified over the last few years as a result of the increase in food prices and biofuel demand. Land grabbing is inherently associated with an appropriation of freshwater resources that has never been investigated before. Here we provide a global assessment of the total grabbed land and water resources. Using process-based agro-hydrological models we estimate the rates of freshwater grabbing worldwide. We find that this phenomenon is occurring at alarming rates in all continents except Antarctica. The per capita volume of grabbed water often exceeds the water requirements for a balanced diet and would be sufficient to abate malnourishment in the grabbed countries. High rates of water grabbing are often associated with deforestation and the increase in water withdrawals for irrigation.

  10. Polyandry in nature: a global analysis.

    Science.gov (United States)

    Taylor, Michelle L; Price, Tom A R; Wedell, Nina

    2014-07-01

    A popular notion in sexual selection is that females are polyandrous and their offspring are commonly sired by more than a single male. We now have large-scale evidence from natural populations to be able to verify this assumption. Although we concur that polyandry is a generally common and ubiquitous phenomenon, we emphasise that it remains variable. In particular, the persistence of single paternity, both within and between populations, requires more careful consideration. We also explore an intriguing relation of polyandry with latitude. Several recent large-scale analyses of the relations between key population fitness variables, such as heterozygosity, effective population size (Ne), and inbreeding coefficients, make it possible to examine the global effects of polyandry on population fitness for the first time. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  11. Global and Stochastic Analysis with Applications to Mathematical Physics

    CERN Document Server

    Gliklikh, Yuri E

    2011-01-01

    Methods of global analysis and stochastic analysis are most often applied in mathematical physics as separate entities, thus forming important directions in the field. However, while combination of the two subject areas is rare, it is fundamental for the consideration of a broader class of problems This book develops methods of Global Analysis and Stochastic Analysis such that their combination allows one to have a more or less common treatment for areas of mathematical physics that traditionally are considered as divergent and requiring different methods of investigation Global and Stochastic Analysis with Applications to Mathematical Physics covers branches of mathematics that are currently absent in monograph form. Through the demonstration of new topics of investigation and results, both in traditional and more recent problems, this book offers a fresh perspective on ordinary and stochastic differential equations and inclusions (in particular, given in terms of Nelson's mean derivatives) on linear spaces ...

  12. Current Mooring Design in Partner WECs and Candidates for Preliminary Analysis

    DEFF Research Database (Denmark)

    Thomsen, Jonas Bjerg; Ferri, Francesco; Kofoed, Jens Peter

    This report is the combined report of Commercial Milestone "CM1: Design and Cost of Current Mooring Solutions of Partner WECs" and Milestone "M3: Mooring Solutions for Preliminary Analysis" of the EUDP project "Mooring Solutions for Large Wave Energy Converters". The report covers a description...... of the current mooring design of the partner Wave Energy Converter (WEC) developers in the project, together with a preliminary cost estimate of the systems....

  13. Preliminary Dynamic Siol-Structure-Interaction Analysis for the Waste Handling Building

    Energy Technology Data Exchange (ETDEWEB)

    G. Wagenblast

    2000-05-01

    The objective of this analysis package is to document a preliminary dynamic seismic evaluation of a simplified design concept of the Wade Handling Building (WHB). Preliminary seismic ground motions and soil data will be used. Loading criteria of the WHB System Design Description will be used. Detail design of structural members will not be performed.. The results of the analysis will be used to determine preliminary sizes of structural concrete and steel members and to determine whether the seismic response of the structure is within an acceptable level for future License Application design of safety related facilities. In order to complete this preliminary dynamic evaluation to meet the Site Recommendation (SR) schedule, the building configuration was ''frozen in time'' as the conceptual design existed in October 1999. Modular design features and dry or wet waste storage features were intentionally excluded from this preliminary dynamic seismic evaluation. The document was prepared in accordance with the Development Plan for the ''Preliminary/Dynamic Soil Structure Interaction Analysis for the Waste Handling Building'' (CRWMS M&O 2000b), which was completed, in accordance with AP-2.13Q, ''Technical Product Development Planning''.

  14. Community Analysis of Global Financial Markets

    Directory of Open Access Journals (Sweden)

    Irena Vodenska

    2016-05-01

    Full Text Available We analyze the daily returns of stock market indices and currencies of 56 countries over the period of 2002–2012. We build a network model consisting of two layers, one being the stock market indices and the other the foreign exchange markets. Synchronous and lagged correlations are used as measures of connectivity and causality among different parts of the global economic system for two different time intervals: non-crisis (2002–2006 and crisis (2007–2012 periods. We study community formations within the network to understand the influences and vulnerabilities of specific countries or groups of countries. We observe different behavior of the cross correlations and communities for crisis vs. non-crisis periods. For example, the overall correlation of stock markets increases during crisis while the overall correlation in the foreign exchange market and the correlation between stock and foreign exchange markets decrease, which leads to different community structures. We observe that the euro, while being central during the relatively calm period, loses its dominant role during crisis. Furthermore we discover that the troubled Eurozone countries, Portugal, Italy, Greece and Spain, form their own cluster during the crisis period.

  15. Thermal Hydraulic Analysis of K-DEMO Single Blanket Module for Preliminary Accident Analysis using MELCOR

    Energy Technology Data Exchange (ETDEWEB)

    Moon, Sung Bo; Bang, In Cheol [UNIST, Ulsan (Korea, Republic of)

    2016-05-15

    To develop the Korean fusion commercial reactor, preliminary design concept for K-DEMO (Korean fusion demonstration reactor) has been announced by NFRI (National Fusion Research Institute). This pre-conceptual study of K-DEMO has been introduced to identify technical details of a fusion power plant for the future commercialization of fusion reactor in Korea. Before this consideration, to build the K-DEMO, accident analysis is essential. Since the Fukushima accident, which is severe accident from unexpected disaster, safety analysis of nuclear power plant has become important. The safety analysis of both fission and fusion reactors is deemed crucial in demonstrating the low radiological effect of these reactors on the environment, during severe accidents. A risk analysis of K-DEMO should be performed, as a prerequisite for the construction of a fusion reactor. In this research, thermal-hydraulic analysis of single blanket module of K-DEMO is conducted for preliminary accident analysis for K-DEMO. Further study about effect of flow distributer is conducted. The normal K-DEMO operation condition is applied to the boundary condition and simulated to verify the material temperature limit using MELCOR. MELCOR is fully integrated, relatively fast-running code developed by Sandia National Laboratories. MELCOR had been used for Light Water Reactors and fusion reactor version of MELCOR was developed for ITER accident analysis. This study shows the result of thermal-hydraulic simulation of single blanket module with MELCOR which is severe accident code for nuclear fusion safety analysis. The difference of mass flow rate for each coolant channel with or without flow distributer is presented. With flow distributer, advantage of broadening temperature gradient in the K-DEMO blanket module and increase mass flow toward first wall is obtained. This can enhance the safety of K-DEMO blanket module. Most 13 .deg. C temperature difference in blanket module is obtained.

  16. Comprehensive Security Framework for Global Threads Analysis

    CERN Document Server

    Saraydaryan, Jacques; Ubeda, Stephane

    2009-01-01

    Cyber criminality activities are changing and becoming more and more professional. With the growth of financial flows through the Internet and the Information System (IS), new kinds of thread arise involving complex scenarios spread within multiple IS components. The IS information modeling and Behavioral Analysis are becoming new solutions to normalize the IS information and counter these new threads. This paper presents a framework which details the principal and necessary steps for monitoring an IS. We present the architecture of the framework, i.e. an ontology of activities carried out within an IS to model security information and User Behavioral analysis. The results of the performed experiments on real data show that the modeling is effective to reduce the amount of events by 91%. The User Behavioral Analysis on uniform modeled data is also effective, detecting more than 80% of legitimate actions of attack scenarios.

  17. Comprehensive Security Framework for Global Threats Analysis

    Directory of Open Access Journals (Sweden)

    Veronique Legrand

    2009-08-01

    Full Text Available Cyber criminality activities are changing and becoming more and more professional. With the growth of financial flows through the Internet and the Information System (IS, new kinds of thread arise involving complex scenarios spread within multiple IS components. The IS information modeling and Behavioral Analysis are becoming new solutions to normalize the IS information and counter these new threads. This paper presents a framework which details the principal and necessary steps for monitoring an IS. We present the architecture of the framework, i.e. an ontology of activities carried out within an IS to model security information and User Behavioral analysis. The results of the performed experiments on real data show that the modeling is effective to reduce the amount of events by 91%. The User Behavioral Analysis on uniform modeled data is also effective, detecting more than 80% of legitimate actions of attack scenarios.

  18. Analysis of Facts and Dilemmas of Globalization Activities

    OpenAIRE

    Linda Jurakovic; Giorgio Cadum; Goran Fabris

    2006-01-01

    This paper critically analyzes the key elements (world trends, national identity, human resources, market) of the effects of globalization on the market, as well as the role of our country in the entire process, listing practical examples. Through comparison and analysis of the available literature and experience, it was concluded that there is a dual impact of globalization in the economic sphere and the need for including management into world trends is increasing. The turbulent environment...

  19. Cusum charts for preliminary analysis of individual observations

    OpenAIRE

    1997-01-01

    textabstractA preliminary Cusum chart based on individual observations is developed from the uniformly most powerful test for the detection of linear trends. This Cusum chart is compared with several of its competitors which are based on the likelihood ratio test and on transformations of standardized recursive residuals on which for instance the Q-chart methodology is based. It turns out that the new proposed Cusum chart is not only superior in the detection of linear trend out-of-control co...

  20. Grid-connected ICES preliminary feasibility analysis and evaluation. Final report. Volume I. Executive summary

    Energy Technology Data Exchange (ETDEWEB)

    1977-06-30

    A group of hospitals, clinics, research facilities, and medical education facilities, known as the HEAL Complex, was chosen as the site (in New Orleans) for the demonstration of a Grid-Connected Integrated Community Energy System (ICES). The contract work included a preliminary energy supply/demand assessment of the Demonstration Community, a preliminary feasibility analysis and conceptual design of a candidate Demonstration System, preliminary assessment of institutional factors, preparation of a detailed work management plan for subsequent phases of the demonstration program, firming-up of commitments from participating parties, and reporting thereon. This Phase I study has indicated that a central ICES plant producing steam, chilled water, and by-product electricity to serve the HEAL Complex is technically and economically feasible to the extent that Phase II, Detailed Feasibility and Preliminary Design, should be implemented. (MCW)

  1. COMPARATIVE ANALYSIS OF GLOBAL TERTIARY EDUCATIONAL SYSTEMS

    Directory of Open Access Journals (Sweden)

    Ciumas Cristina

    2013-07-01

    Full Text Available Higher education system occupies a special place in the policy of each nation. Regardless of geographical location, socio-economic or cultural differences, the need to improve the education offered for population by facilitating access to higher education becomes more and more important. Providing a suitable framework for the personal development of each student is expensive and involves high amounts of money. From the analyses carried out we couldn\\'t identify the substantial differences between the way it is structured and organized education system worldwide. However, we were able to identify a number of common elements that create a global University System. The need to invest in human resources through structural reforms in each country is present, and therefore a higher indention to pay greater attention to the development of the higher education system. In our work we decided to analyze education systems in countries like United States of America (USA, United Kingdom (GB, China (CHN, Germany (DE, France (FR, Russian Federation (RU, Japan (JPN average values recorded for EU-27 and last but not least Romania (RO. Although the investment in the University system is hard to quantify, it is unanimously acknowledged that a country can achieve a competitive advantage in international relations through a very well prepared and trained personnel. The countries reviewed in this paper have different policies when it comes to financial support of the University System. If Germany and France have decided to get involved directly in supporting the system by allocating the necessary funds from the State budget, another European country, the United Kingdom, decided to apply a policy diametrically opposite, similar to that existing in the USA and cover in a lesser degree the needs of universities in Government funds. Regardless of the policy adopted the results are intended to be the same: facilitating access to university education, a high quality of

  2. Efficient Global Programming Model for Discriminant Analysis

    Directory of Open Access Journals (Sweden)

    M.ANGULAKSHMI

    2011-03-01

    Full Text Available Conventional statistical analysis includes the capacity to systematically assign individuals to groups. We suggest alternative assignment procedures, utilizing a set of interrelated goal programming formulations. This paper represents an effort to suggest ways by which the discriminant problem might reasonably be addressed via straightforward linear goal programming formulations. Simple and direct, such formulations may ultimately compete with conventional approaches - free of the classical assumptions and possessing a stronger intuitive appeal. We further demonstrate via simple illustration the potential of these procedures to play a significant part in addressing the discriminant problem, and indicate fundamental ideas that lay the foundation for other more sophisticated approaches.

  3. Bayesian global analysis of neutrino oscillation data

    CERN Document Server

    Bergstrom, Johannes; Maltoni, Michele; Schwetz, Thomas

    2015-01-01

    We perform a Bayesian analysis of current neutrino oscillation data. When estimating the oscillation parameters we find that the results generally agree with those of the $\\chi^2$ method, with some differences involving $s_{23}^2$ and CP-violating effects. We discuss the additional subtleties caused by the circular nature of the CP-violating phase, and how it is possible to obtain correlation coefficients with $s_{23}^2$. When performing model comparison, we find that there is no significant evidence for any mass ordering, any octant of $s_{23}^2$ or a deviation from maximal mixing, nor the presence of CP-violation.

  4. A generalized preimage theorem in global analysis

    Institute of Scientific and Technical Information of China (English)

    MA; Jipu

    2001-01-01

    [1]Ma Jipu, (1.2) inverses of operators between Banach spaces and conjugacy theorem, Chinese Annals of Math., B, 1999, 20(1): 57.[2]Ma Jipu, Rank theorem of operators between Banach spaces, Science in China, Ser. A, 2000, 43(1): 1.[3]Ma Jipu, Local conjugacy theorem, rank theorems in advenced calculus and a generalized principle constructing Banach manifolds, Science in China, Ser. A, 2000, 43(12): 1233.[4]Zeidler, A. E., Nonlinear Function Analysis and Its Applications, IV: Applications to Mathematical Physics, New York: Springer-Verlag, 1988.

  5. Turbine Fuels from Tar Sands Bitumen and Heavy Oil. Phase I. Preliminary Process Analysis.

    Science.gov (United States)

    1985-04-09

    Process Analysis A. F. Talbot. V. Elanchenny, L. H. Finkel, A. Macris and 3. P. Schwedock Sun Tech, Inc., A Subsidiary of Sun Co. P. 0. Box 1135 Marcus Hook...investigation be carried out in three discrete phases, as described below: Phase I - Preliminary process analysis includes an eval- uation of the potential of

  6. A Preliminary Study on Gender Differences in Studying Systems Analysis and Design

    Science.gov (United States)

    Lee, Fion S. L.; Wong, Kelvin C. K.

    2017-01-01

    Systems analysis and design is a crucial task in system development and is included in a typical information systems programme as a core course. This paper presented a preliminary study on gender differences in studying a systems analysis and design course of an undergraduate programme. Results indicated that male students outperformed female…

  7. Recurrence quantification analysis of global stock markets

    Science.gov (United States)

    Bastos, João A.; Caiado, Jorge

    2011-04-01

    This study investigates the presence of deterministic dependencies in international stock markets using recurrence plots and recurrence quantification analysis (RQA). The results are based on a large set of free float-adjusted market capitalization stock indices, covering a period of 15 years. The statistical tests suggest that the dynamics of stock prices in emerging markets is characterized by higher values of RQA measures when compared to their developed counterparts. The behavior of stock markets during critical financial events, such as the burst of the technology bubble, the Asian currency crisis, and the recent subprime mortgage crisis, is analyzed by performing RQA in sliding windows. It is shown that during these events stock markets exhibit a distinctive behavior that is characterized by temporary decreases in the fraction of recurrence points contained in diagonal and vertical structures.

  8. Principal component analysis of global maps of the total electronic content

    Science.gov (United States)

    Maslennikova, Yu. S.; Bochkarev, V. V.

    2014-03-01

    In this paper we present results of the spatial distribution analysis of the total electron content (TEC) performed by the Principal Component Analysis (PCA) with the use of global maps of TEC provided by the JPL laboratory (Jet Propulsion Laboratory, NASA, USA) for the period from 2004 to 2010. We show that the obtained components of the decomposition of TEC essentially depend on the representation of the initial data and the method of their preliminary processing. We propose a technique for data centering that allows us to take into account the influence of diurnal and seasonal factors. We establish a correlation between amplitudes of the first components of the decomposition of TEC (connected with the equatorial anomaly) and the solar activity index F10.7, as well as with the flow of high energy particles of the solar wind.

  9. Optimizing human activity patterns using global sensitivity analysis.

    Science.gov (United States)

    Fairchild, Geoffrey; Hickmann, Kyle S; Mniszewski, Susan M; Del Valle, Sara Y; Hyman, James M

    2014-12-01

    Implementing realistic activity patterns for a population is crucial for modeling, for example, disease spread, supply and demand, and disaster response. Using the dynamic activity simulation engine, DASim, we generate schedules for a population that capture regular (e.g., working, eating, and sleeping) and irregular activities (e.g., shopping or going to the doctor). We use the sample entropy (SampEn) statistic to quantify a schedule's regularity for a population. We show how to tune an activity's regularity by adjusting SampEn, thereby making it possible to realistically design activities when creating a schedule. The tuning process sets up a computationally intractable high-dimensional optimization problem. To reduce the computational demand, we use Bayesian Gaussian process regression to compute global sensitivity indices and identify the parameters that have the greatest effect on the variance of SampEn. We use the harmony search (HS) global optimization algorithm to locate global optima. Our results show that HS combined with global sensitivity analysis can efficiently tune the SampEn statistic with few search iterations. We demonstrate how global sensitivity analysis can guide statistical emulation and global optimization algorithms to efficiently tune activities and generate realistic activity patterns. Though our tuning methods are applied to dynamic activity schedule generation, they are general and represent a significant step in the direction of automated tuning and optimization of high-dimensional computer simulations.

  10. Preliminary Evaluation of MapReduce for High-Performance Climate Data Analysis

    Science.gov (United States)

    Duffy, D. Q.; Schnase, J. L.; Clune, T. L.; Kim, E. J.; Freeman, S. M.; Thompson, J. H.; Hunter, K. A.; Theriot, M. E.

    2011-12-01

    Data intensive analytic workflows bridge between the largely unstructured mass of stored scientific data and the highly structured, tailored, reduced, and refined products used by scientists in their research. In general, the initial steps of an analysis, those operations that first interact with a data repository, tend to be the most general, while data manipulations closer to the client tend to be the most specialized to the individual, to the domain, or to the science question under study. The amount of data being operated on also tends to be larger on the repository-side of the workflow, smaller toward the client-side end products. We are using MapReduce to exploit this natural stratification, optimize efficiencies along the workflow chain, and provide a preliminary qualitative and quantitative assessment of MapReduce as a means of enabling server-side, distributed climate data analysis. MapReduce is a model for distributed storage and computation that seeks to improve efficiencies of the near-archive operations that initiate workflows. Simply put, MapReduce stores chunked data on disks with associated processors in such a way that operations on the chunked data can occur in parallel and return meaningfully aggregated results. While MapReduce has proven effective for large repositories of textual data, its use in data intensive science applications has been limited, because many scientific data sets are inherently complex, have high dimensionality, and use binary formats. We are using Apache's open-source Hadoop software implementation of MapReduce on top of the Hadoop Filesystem in our evaluation. Our analyses focus on soil moisture, precipitation, and atmospheric water-vapor, important classes of observation- and simulation-derived data products. The specific data sets being used in the evaluation include MERRA monthly precipitation and soil moisture products; the MODIS Atmospheres, 8-day global water-vapor product; and the SMOS 3-day global soil moisture

  11. A global optimization approach to multi-polarity sentiment analysis.

    Science.gov (United States)

    Li, Xinmiao; Li, Jing; Wu, Yukeng

    2015-01-01

    Following the rapid development of social media, sentiment analysis has become an important social media mining technique. The performance of automatic sentiment analysis primarily depends on feature selection and sentiment classification. While information gain (IG) and support vector machines (SVM) are two important techniques, few studies have optimized both approaches in sentiment analysis. The effectiveness of applying a global optimization approach to sentiment analysis remains unclear. We propose a global optimization-based sentiment analysis (PSOGO-Senti) approach to improve sentiment analysis with IG for feature selection and SVM as the learning engine. The PSOGO-Senti approach utilizes a particle swarm optimization algorithm to obtain a global optimal combination of feature dimensions and parameters in the SVM. We evaluate the PSOGO-Senti model on two datasets from different fields. The experimental results showed that the PSOGO-Senti model can improve binary and multi-polarity Chinese sentiment analysis. We compared the optimal feature subset selected by PSOGO-Senti with the features in the sentiment dictionary. The results of this comparison indicated that PSOGO-Senti can effectively remove redundant and noisy features and can select a domain-specific feature subset with a higher-explanatory power for a particular sentiment analysis task. The experimental results showed that the PSOGO-Senti approach is effective and robust for sentiment analysis tasks in different domains. By comparing the improvements of two-polarity, three-polarity and five-polarity sentiment analysis results, we found that the five-polarity sentiment analysis delivered the largest improvement. The improvement of the two-polarity sentiment analysis was the smallest. We conclude that the PSOGO-Senti achieves higher improvement for a more complicated sentiment analysis task. We also compared the results of PSOGO-Senti with those of the genetic algorithm (GA) and grid search method. From

  12. Globalization

    Institute of Scientific and Technical Information of China (English)

    范玮丽

    2008-01-01

    This paper mainly talks about the currently hot topic-globalization. Firstly, it brings out the general trend about globalization and how to better understand its implication. Secondly, it largely focuses on how to deal with it properly, especially for international marketers. Then, facing with the overwhelming trend, it is time for us to think about seriously what has globalization brought to us. Last but not least, it summarized the author's personal view about the future of globalization and how should we go.

  13. Global atmospheric response to specific linear combinations of the main SST modes.. Part I: numerical experiments and preliminary results

    Science.gov (United States)

    Trzaska, S.; Moron, V.; Fontaine, B.

    1996-10-01

    This article investigates through numerical experiments the controversial question of the impact of El Niño-Southern Oscillation (ENSO) phenomena on climate according to large-scale and regional-scale interhemispheric thermal contrast. Eight experiments (two considering only inversed Atlantic thermal anomalies and six combining ENSO warm phase with large-scale interhemispheric contrast and Atlantic anomaly patterns) were performed with the Météo-France atmospheric general circulation model. The definition of boundary conditions from observed composites and principal components is presented and preliminary results concerning the month of August, especially over West Africa and the equatorial Atlantic are discussed. Results are coherent with observations and show that interhemispheric and regional scale sea-surface-temperature anomaly (SST) patterns could significantly modulate the impact of ENSO phenomena: the impact of warm-phase ENSO, relative to the atmospheric model intercomparison project (AMIP) climatology, seems stronger when embedded in global and regional SSTA patterns representative of the post-1970 conditions [i.e. with temperatures warmer (colder) than the long-term mean in the southern hemisphere (northern hemisphere)]. Atlantic SSTAs may also play a significant role. Acknowledgements. We gratefully appreciate the on-line DMSP database facility at APL (Newell et al., 1991) from which this study has benefited greatly. We wish to thank E. Friis-Christensen for his encouragement and useful discussions. A. Y. would like to thank the Danish Meteorological Institute, where this work was done, for its hospitality during his stay there and the Nordic Baltic Scholarship Scheme for its financial support of this stay. Topical Editor K.-H. Glassmeier thanks M. J. Engebretson and H. Lühr for their help in evaluating this paper.--> Correspondence to: A. Yahnin-->

  14. Global multi-level analysis of the 'scientific food web'.

    Science.gov (United States)

    Mazloumian, Amin; Helbing, Dirk; Lozano, Sergi; Light, Robert P; Börner, Katy

    2013-01-01

    We introduce a network-based index analyzing excess scientific production and consumption to perform a comprehensive global analysis of scholarly knowledge production and diffusion on the level of continents, countries, and cities. Compared to measures of scientific production and consumption such as number of publications or citation rates, our network-based citation analysis offers a more differentiated picture of the 'ecosystem of science'. Quantifying knowledge flows between 2000 and 2009, we identify global sources and sinks of knowledge production. Our knowledge flow index reveals, where ideas are born and consumed, thereby defining a global 'scientific food web'. While Asia is quickly catching up in terms of publications and citation rates, we find that its dependence on knowledge consumption has further increased.

  15. Simulation analysis of globally integrated logistics and recycling strategies

    Energy Technology Data Exchange (ETDEWEB)

    Song, S.J.; Hiroshi, K. [Hiroshima Inst. of Tech., Graduate School of Mechanical Systems Engineering, Dept. of In formation and Intelligent Systems Engineering, Hiroshima (Japan)

    2004-07-01

    This paper focuses on the optimal analysis of world-wide recycling activities associated with managing the logistics and production activities in global manufacturing whose activities stretch across national boundaries. Globally integrated logistics and recycling strategies consist of the home country and two free trading economic blocs, NAFTA and ASEAN, where significant differences are found in production and disassembly cost, tax rates, local content rules and regulations. Moreover an optimal analysis of globally integrated value-chain was developed by applying simulation optimization technique as a decision-making tool. The simulation model was developed and analyzed by using ProModel packages, and the results help to identify some of the appropriate conditions required to make well-performed logistics and recycling plans in world-wide collaborated manufacturing environment. (orig.)

  16. Globalization

    Directory of Open Access Journals (Sweden)

    Tulio Rosembuj

    2006-12-01

    Full Text Available There is no singular globalization, nor is the result of an individual agent. We could start by saying that global action has different angles and subjects who perform it are different, as well as its objectives. The global is an invisible invasion of materials and immediate effects.

  17. Thick Concrete Specimen Construction, Testing, and Preliminary Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Clayton, Dwight A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Hoegh, Kyle [Univ. of Minnesota, Minneapolis, MN (United States); Khazanovich, Lev [Univ. of Minnesota, Minneapolis, MN (United States)

    2015-03-01

    The purpose of the U.S. Department of Energy Office of Nuclear Energy’s Light Water Reactor Sustainability (LWRS) Program is to develop technologies and other solutions that can improve the reliability, sustain the safety, and extend the operating lifetimes of nuclear power plants (NPPs) beyond 60 years. Since many important safety structures in an NPP are constructed of concrete, inspection techniques must be developed and tested to evaluate the internal condition. In-service containment structures generally do not allow for the destructive measures necessary to validate the accuracy of these inspection techniques. This creates a need for comparative testing of the various nondestructive evaluation (NDE) measurement techniques on concrete specimens with known material properties, voids, internal microstructure flaws, and reinforcement locations. A preliminary report detailed some of the challenges associated with thick reinforced concrete sections and prioritized conceptual designs of specimens that could be fabricated to represent NPP concrete structures for using in NDE evaluation comparisons. This led to the construction of the concrete specimen presented in this report, which has sufficient reinforcement density and cross-sectional size to represent an NPP containment wall. Details on how a suitably thick concrete specimen was constructed are presented, including the construction materials, final nominal design schematic, as well as formwork and rigging required to safely meet the desired dimensions of the concrete structure. The report also details the type and methods of forming the concrete specimen as well as information on how the rebar and simulated defects were embedded. Details on how the resulting specimen was transported, safely anchored, and marked to allow access for systematic comparative NDE testing of defects in a representative NPP containment wall concrete specimen are also given. Data collection using the MIRA Ultrasonic NDE equipment and

  18. Global Analysis of Helicity PDFs: past - present - future

    Energy Technology Data Exchange (ETDEWEB)

    de Florian, D.; Stratmann, M.; Sassot, R.; Vogelsang, W.

    2011-04-11

    We discuss the current status of the DSSV global analysis of helicity-dependent parton densities. A comparison with recent semi-inclusive DIS data from COMPASS is presented, and constraints on the polarized strangeness density are examined in some detail.

  19. Global Analysis of Horizontal Gene Transfer in Fusarium verticillioides

    Science.gov (United States)

    The co-occurrence of microbes within plants and other specialized niches may facilitate horizontal gene transfer (HGT) affecting host-pathogen interactions. We recently identified fungal-to-fungal HGTs involving metabolic gene clusters. For a global analysis of HGTs in the maize pathogen Fusarium ve...

  20. Globalization and International Student Mobility: A Network Analysis

    Science.gov (United States)

    Shields, Robin

    2013-01-01

    This article analyzes changes to the network of international student mobility in higher education over a 10-year period (1999-2008). International student flows have increased rapidly, exceeding 3 million in 2009, and extensive data on mobility provide unique insight into global educational processes. The analysis is informed by three theoretical…

  1. Statistical analysis of measured global insolation data for Pakistan

    Energy Technology Data Exchange (ETDEWEB)

    Raja, I.A. (Balochistan Univ., Quetta (Pakistan). Dept. of Physics); Twidell, J.W. (Strathclyde Univ., Glasgow (United Kingdom). Energy Studies Unit)

    1994-01-01

    The global insolation data for up to 15 years from six locations in Pakistan are analysed. In addition to simple arithmetic analysis, tables and figures of cumulative frequency distribution and number of consecutive days above certain threshold insolation values are constructed. Results are presented for monthly and annual periods for practical application when planning solar installation. (author)

  2. Ecological network analysis on global virtual water trade.

    Science.gov (United States)

    Yang, Zhifeng; Mao, Xufeng; Zhao, Xu; Chen, Bin

    2012-02-07

    Global water interdependencies are likely to increase with growing virtual water trade. To address the issues of the indirect effects of water trade through the global economic circulation, we use ecological network analysis (ENA) to shed insight into the complicated system interactions. A global model of virtual water flow among agriculture and livestock production trade in 1995-1999 is also built as the basis for network analysis. Control analysis is used to identify the quantitative control or dependency relations. The utility analysis provides more indicators for describing the mutual relationship between two regions/countries by imitating the interactions in the ecosystem and distinguishes the beneficiary and the contributor of virtual water trade system. Results show control and utility relations can well depict the mutual relation in trade system, and direct observable relations differ from integral ones with indirect interactions considered. This paper offers a new way to depict the interrelations between trade components and can serve as a meaningful start as we continue to use ENA in providing more valuable implications for freshwater study on a global scale.

  3. Global and local sensitivity analysis methods for a physical system

    Energy Technology Data Exchange (ETDEWEB)

    Morio, Jerome, E-mail: jerome.morio@onera.fr [Onera-The French Aerospace Lab, F-91761, Palaiseau Cedex (France)

    2011-11-15

    Sensitivity analysis is the study of how the different input variations of a mathematical model influence the variability of its output. In this paper, we review the principle of global and local sensitivity analyses of a complex black-box system. A simulated case of application is given at the end of this paper to compare both approaches.

  4. Globalization and International Student Mobility: A Network Analysis

    Science.gov (United States)

    Shields, Robin

    2013-01-01

    This article analyzes changes to the network of international student mobility in higher education over a 10-year period (1999-2008). International student flows have increased rapidly, exceeding 3 million in 2009, and extensive data on mobility provide unique insight into global educational processes. The analysis is informed by three theoretical…

  5. Global and Local Sensitivity Analysis Methods for a Physical System

    Science.gov (United States)

    Morio, Jerome

    2011-01-01

    Sensitivity analysis is the study of how the different input variations of a mathematical model influence the variability of its output. In this paper, we review the principle of global and local sensitivity analyses of a complex black-box system. A simulated case of application is given at the end of this paper to compare both approaches.…

  6. Methods for global sensitivity analysis in life cycle assessment

    NARCIS (Netherlands)

    Groen, Evelyne A.; Bokkers, Eddy; Heijungs, Reinout; Boer, de Imke J.M.

    2017-01-01

    Purpose: Input parameters required to quantify environmental impact in life cycle assessment (LCA) can be uncertain due to e.g. temporal variability or unknowns about the true value of emission factors. Uncertainty of environmental impact can be analysed by means of a global sensitivity analysis to

  7. Preliminary Analysis of Species Partitioning in the DWPF Melter

    Energy Technology Data Exchange (ETDEWEB)

    Choi, A. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Kesterson, M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Johnson, F. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); McCabe, D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-07-15

    The work described in this report is preliminary in nature since its goal was to demonstrate the feasibility of estimating the off-gas entrainment rates from the Defense Waste Processing Facility (DWPF) melter based on a simple mass balance using measured feed and glass pour stream compositions and timeaveraged melter operating data over the duration of one canister-filling cycle. The only case considered in this study involved the SB6 pour stream sample taken while Canister #3472 was being filled over a 20-hour period on 12/20/2010, approximately three months after the bubblers were installed. The analytical results for that pour stream sample provided the necessary glass composition data for the mass balance calculations. To estimate the “matching” feed composition, which is not necessarily the same as that of the Melter Feed Tank (MFT) batch being fed at the time of pour stream sampling, a mixing model was developed involving three preceding MFT batches as well as the one being fed at that time based on the assumption of perfect mixing in the glass pool but with an induction period to account for the process delays involved in the calcination/fusion step in the cold cap and the melter turnover.

  8. Preliminary Coupling of MATRA Code for Multi-physics Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seongjin; Choi, Jinyoung; Yang, Yongsik; Kwon, Hyouk; Hwang, Daehyun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-05-15

    The boundary conditions such as the inlet temperature, mass flux, averaged heat flux, power distributions of the rods, and core geometry is given by constant values or functions of time. These conditions are separately calculated and provided by other codes, such as a neutronics or a system codes, into the MATRA code. In addition, the coupling of several codes in the different physics field is focused and embodied. In this study, multiphysics coupling methods were developed for a subchannel code (MATRA) with neutronics codes (MASTER, DeCART) and a fuel performance code (FRAPCON-3). Preliminary evaluation results for representative sample cases are presented. The MASTER and DeCART codes provide the power distribution of the rods in the core to the MATRA code. In case of the FRAPCON-3 code, the variation of the rod diameter induced by the thermal expansion is yielded and provided. The MATRA code transfers the thermal-hydraulic conditions that each code needs. Moreover, the coupling method with each code is described.

  9. Laboratory Investigations on Estuary Salinity Mixing: Preliminary Analysis

    Directory of Open Access Journals (Sweden)

    F. H. Nuryazmeen

    2014-05-01

    Full Text Available Estuaries are bodies of water along the coasts that are formed when fresh water from rivers flows into and mixes with salt water from the ocean. The estuaries serve as a habitat to some aquatic lives, including mangroves. Human-induced activities such as dredging of shipping lanes along the bottom estuarine, the disposal of industrial wastes into the water system and shoreline development influence estuarine dynamics which include mixing process. These activities might contribute to salinity changes and further adversely affect the estuarine ecosystem. In order to study at the characteristics of the mixing between salt water (estuary and freshwater (river, a preliminary investigation had been done in the laboratory. Fresh water was released from one end of the flume and overflowing at weir at the other end. Meanwhile, salt water was represented by the red dye tracer released through a weir and intruded upstream as a gravity current. The isohalines are plotted to see the salinity patterns. Besides, to examine the spatial and temporal salinity profiles along the laboratory investigations, the plotted graphs have been made. The results show that the changes in salinity level along the flume due to mixing between fresh water and salt water. This showed typical salt-wedge estuary characteristics.

  10. Fukushima Daiichi unit 1 uncertainty analysis--Preliminary selection of uncertain parameters and analysis methodology

    Energy Technology Data Exchange (ETDEWEB)

    Cardoni, Jeffrey N.; Kalinich, Donald A.

    2014-02-01

    Sandia National Laboratories (SNL) plans to conduct uncertainty analyses (UA) on the Fukushima Daiichi unit (1F1) plant with the MELCOR code. The model to be used was developed for a previous accident reconstruction investigation jointly sponsored by the US Department of Energy (DOE) and Nuclear Regulatory Commission (NRC). However, that study only examined a handful of various model inputs and boundary conditions, and the predictions yielded only fair agreement with plant data and current release estimates. The goal of this uncertainty study is to perform a focused evaluation of uncertainty in core melt progression behavior and its effect on key figures-of-merit (e.g., hydrogen production, vessel lower head failure, etc.). In preparation for the SNL Fukushima UA work, a scoping study has been completed to identify important core melt progression parameters for the uncertainty analysis. The study also lays out a preliminary UA methodology.

  11. Revealing the underlying drivers of disaster risk: a global analysis

    Science.gov (United States)

    Peduzzi, Pascal

    2017-04-01

    Disasters events are perfect examples of compound events. Disaster risk lies at the intersection of several independent components such as hazard, exposure and vulnerability. Understanding the weight of each component requires extensive standardisation. Here, I show how footprints of past disastrous events were generated using GIS modelling techniques and used for extracting population and economic exposures based on distribution models. Using past event losses, it was possible to identify and quantify a wide range of socio-politico-economic drivers associated with human vulnerability. The analysis was applied to about nine thousand individual past disastrous events covering earthquakes, floods and tropical cyclones. Using a multiple regression analysis on these individual events it was possible to quantify each risk component and assess how vulnerability is influenced by various hazard intensities. The results show that hazard intensity, exposure, poverty, governance as well as other underlying factors (e.g. remoteness) can explain the magnitude of past disasters. Analysis was also performed to highlight the role of future trends in population and climate change and how this may impacts exposure to tropical cyclones in the future. GIS models combined with statistical multiple regression analysis provided a powerful methodology to identify, quantify and model disaster risk taking into account its various components. The same methodology can be applied to various types of risk at local to global scale. This method was applied and developed for the Global Risk Analysis of the Global Assessment Report on Disaster Risk Reduction (GAR). It was first applied on mortality risk in GAR 2009 and GAR 2011. New models ranging from global assets exposure and global flood hazard models were also recently developed to improve the resolution of the risk analysis and applied through CAPRA software to provide probabilistic economic risk assessments such as Average Annual Losses (AAL

  12. ANSI/ASHRAE/IES Standard 90.1-2013 Preliminary Determination: Quantitative Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Halverson, Mark A.; Rosenberg, Michael I.; Wang, Weimin; Zhang, Jian; Mendon, Vrushali V.; Athalye, Rahul A.; Xie, YuLong; Hart, Reid; Goel, Supriya

    2014-03-01

    This report provides a preliminary quantitative analysis to assess whether buildings constructed according to the requirements of ANSI/ASHRAE/IES Standard 90.1-2013 would result in energy savings compared with buildings constructed to ANSI/ASHRAE/IES Standard 90.1-2010.

  13. Preliminary Analysis of the Oklahoma Wavefields Demonstration Dataset

    Science.gov (United States)

    Anderson, K. R.; Sweet, J. R.; Woodward, R.; Karplus, M. S.; DeShon, H. R.; Magnani, M. B.; Hayward, C.; Langston, C. A.

    2016-12-01

    In June 2016, a field crew of 50 students, faculty, industry personnel and IRIS staff deployed a total of 390 stations as part of a community seismic experiment above an active seismic lineament in north-central Oklahoma. The goals of the experiment were to test new instrumentation and deployment strategies that record the full wavefield, and to advance understanding of earthquake source processes and regional lithospheric structure. The crew deployed 363 3C 4.5Hz Generation 2 Fairfield Z-Land nodes along three seismic lines and in a seven-layer nested gradiometer array. The seismic lines spanned a region 13 km long by 5 km wide. The nested gradiometer was designed to measure the full seismic wavefield using standard frequency-wavenumber techniques and spatial wave gradients. A broadband, 18 station "Golay 3x6" array was deployed around the gradiometer and seismic lines with an aperture of approximately 5 km to collect waveform data from local and regional events. In addition, 9 infrasound stations were deployed in order to capture and identify acoustic events that might be recorded by the seismic arrays and to quantify the wind acoustic noise effect on co-located broadband stations. The variety of instrumentation used in this deployment was chosen to capture the full seismic wavefield generated by the local and regional seismicity beneath the array and the surrounding region. We present preliminary results from the data collected during the experiment. We analyze the level of signal coherence observed across the nested gradiometer and Golay array as well as array design fidelity. We report on data quality, including completeness and noise levels, for the various types of instrumentation. We also examine the performance of co-located surface and buried nodes to determine the benefits of each installation type. Finally, we present performance comparisons between co-located nodes and broadband stations and compare these results to prior wavefield/large-N deployments

  14. Preliminary analysis techniques for ring and stringer stiffened cylindrical shells

    Science.gov (United States)

    Graham, J.

    1993-03-01

    This report outlines methods of analysis for the buckling of thin-walled circumferentially and longitudinally stiffened cylindrical shells. Methods of analysis for the various failure modes are presented in one cohesive package. Where applicable, more than one method of analysis for a failure mode is presented along with standard practices. The results of this report are primarily intended for use in launch vehicle design in the elastic range. A Microsoft Excel worksheet with accompanying macros has been developed to automate the analysis procedures.

  15. ANALYSIS OF GLOBAL DYNAMICS IN A PAIAMETIICALLY EXCITED THIN PLATE

    Institute of Scientific and Technical Information of China (English)

    张伟

    2001-01-01

    The global bifurcations and chaos of a simply supported rectangular thin plate with parametric excitation are analyzed. The formulas of the thin plate are derived by yon Karman type equation and Galerkin's approach. The method of multiple scales is used to obtain the averaged equations. Based on the averaged equations, the theory of the normal form is used to give the explicit expressions of the normal form associated with a double zero and a pair of pure imaginary eigenvalues by Maple program. On the basis of the normal form, a global bifurcation analysis of the parametrically excited recta ngular thin plate is given by the global perturbation method developed by Kovacic and Wiggins. The chaotic motion of thin plate is also found by numerical simulation.

  16. Preliminary Design and Analysis of ITER In-Wall Shielding

    Institute of Scientific and Technical Information of China (English)

    LIU Changle; YU Jie; WU Songtao; CAI Yingxiang; PAN Wanjiang

    2007-01-01

    ITER in-wall shielding (IIS) is situated between the doubled shells of the ITER Vacuum Vessel (IVV). Its main functions are applied in shielding neutron, gamma-ray and toroidal field ripple reduction. The structure of IIS has been modelled according to the IVV design criteria which has been updated by the ITER team (IT). Static analysis and thermal expansion analysis were performed for the structure. Thermal-hydraulic analysis verified the heat removal capability and resulting temperature, pressure, and velocity changes in the coolant flow. Consequently, our design work is possibly suitable as a reference for IT's updated or final design in its next step.

  17. Preliminary Technical Risk Analysis for the Geothermal Technologies Program

    Energy Technology Data Exchange (ETDEWEB)

    None

    2009-01-18

    This report explains the goals, methods, and results of a probabilistic analysis of technical risk for a portfolio of R&D projects in the DOE Geothermal Technologies Program (The Program). The analysis is a task by Princeton Energy Resources International, LLC, in support of the National Renewable Energy Laboratory on behalf of the Program. The main challenge in the analysis lies in translating R&D results to a quantitative reflection of technical risk for a key Program metric: levelized cost of energy (LCOE).

  18. First fungal genome sequence from Africa: A preliminary analysis

    Directory of Open Access Journals (Sweden)

    Rene Sutherland

    2012-01-01

    Full Text Available Some of the most significant breakthroughs in the biological sciences this century will emerge from the development of next generation sequencing technologies. The ease of availability of DNA sequence made possible through these new technologies has given researchers opportunities to study organisms in a manner that was not possible with Sanger sequencing. Scientists will, therefore, need to embrace genomics, as well as develop and nurture the human capacity to sequence genomes and utilise the ’tsunami‘ of data that emerge from genome sequencing. In response to these challenges, we sequenced the genome of Fusarium circinatum, a fungal pathogen of pine that causes pitch canker, a disease of great concern to the South African forestry industry. The sequencing work was conducted in South Africa, making F. circinatum the first eukaryotic organism for which the complete genome has been sequenced locally. Here we report on the process that was followed to sequence, assemble and perform a preliminary characterisation of the genome. Furthermore, details of the computer annotation and manual curation of this genome are presented. The F. circinatum genome was found to be nearly 44 million bases in size, which is similar to that of four other Fusarium genomes that have been sequenced elsewhere. The genome contains just over 15 000 open reading frames, which is less than that of the related species, Fusarium oxysporum, but more than that for Fusarium verticillioides. Amongst the various putative gene clusters identified in F. circinatum, those encoding the secondary metabolites fumosin and fusarin appeared to harbour evidence of gene translocation. It is anticipated that similar comparisons of other loci will provide insights into the genetic basis for pathogenicity of the pitch canker pathogen. Perhaps more importantly, this project has engaged a relatively large group of scientists

  19. The Global Challenge of Antimicrobial Resistance: Insights from Economic Analysis

    Directory of Open Access Journals (Sweden)

    Richard J. Zeckhauser

    2010-08-01

    Full Text Available The prevalence of antimicrobial resistance (AR limits the therapeutic options for treatment of infections, and increases the social benefit from disease prevention. Like an environmental resource, antimicrobials require stewardship. The effectiveness of an antimicrobial agent is a global public good. We argue for greater use of economic analysis as an input to policy discussion about AR, including for understanding the incentives underlying health behaviors that spawn AR, and to supplement other methods of tracing the evolution of AR internationally. We also discuss integrating antimicrobial stewardship into global health governance.The prevalence of antimicrobial resistance (AR limits the therapeutic options for treatment of infections, and increases the social benefit from disease prevention. Like an environmental resource, antimicrobials require stewardship. The effectiveness of an antimicrobial agent is a global public good. We argue for greater use of economic analysis as an input to policy discussion about AR, including for understanding the incentives underlying health behaviors that spawn AR, and to supplement other methods of tracing the evolution of AR internationally. We also discuss integrating antimicrobial stewardship into global health governance.

  20. The Future of the Global Environment: A Model-based Analysis Supporting UNEP's First Global Environment Outlook

    NARCIS (Netherlands)

    Bakkes JA; Woerden JW van; Alcamo J; Berk MM; Bol P; Born GJ van den; Brink BJE ten; Hettelingh JP; Langeweg F; Niessen LW; Swart RJ; United Nations Environment; MNV

    1997-01-01

    This report documents the scenario analysis in UNEP's first Global Environment Outlook, published at the same time as the scenario analysis. This Outlook provides a pilot assessment of developments in the environment, both global and regional, between now and 2015, with a further projection to

  1. Performance analysis tool (PATO): Development and preliminary validation

    National Research Council Canada - National Science Library

    Fernando Martins; Filipe Clemente; Frutuoso Silva

    2017-01-01

    .... The Performance Analysis Tool (PATO) software was built with the aim to quickly codify relationships between players and built the adjacency matrices that can be used to test the network measures...

  2. Preliminary Technical Risk Analysis for the Geothermal Technologies Program

    Energy Technology Data Exchange (ETDEWEB)

    McVeigh, J.; Cohen, J.; Vorum, M.; Porro, G.; Nix, G.

    2007-03-01

    This report explains the goals, methods, and results of a probabilistic analysis of technical risk for a portfolio of R&D projects in the DOE Geothermal Technologies Program ('the Program'). The analysis is a task by Princeton Energy Resources International, LLC (PERI), in support of the National Renewable Energy Laboratory (NREL) on behalf of the Program. The main challenge in the analysis lies in translating R&D results to a quantitative reflection of technical risk for a key Program metric: levelized cost of energy (LCOE). This requires both computational development (i.e., creating a spreadsheet-based analysis tool) and a synthesis of judgments by a panel of researchers and experts of the expected results of the Program's R&D.

  3. Lattice Boltzmann methods for global linear instability analysis

    Science.gov (United States)

    Pérez, José Miguel; Aguilar, Alfonso; Theofilis, Vassilis

    2016-11-01

    Modal global linear instability analysis is performed using, for the first time ever, the lattice Boltzmann method (LBM) to analyze incompressible flows with two and three inhomogeneous spatial directions. Four linearization models have been implemented in order to recover the linearized Navier-Stokes equations in the incompressible limit. Two of those models employ the single relaxation time and have been proposed previously in the literature as linearization of the collision operator of the lattice Boltzmann equation. Two additional models are derived herein for the first time by linearizing the local equilibrium probability distribution function. Instability analysis results are obtained in three benchmark problems, two in closed geometries and one in open flow, namely the square and cubic lid-driven cavity flow and flow in the wake of the circular cylinder. Comparisons with results delivered by classic spectral element methods verify the accuracy of the proposed new methodologies and point potential limitations particular to the LBM approach. The known issue of appearance of numerical instabilities when the SRT model is used in direct numerical simulations employing the LBM is shown to be reflected in a spurious global eigenmode when the SRT model is used in the instability analysis. Although this mode is absent in the multiple relaxation times model, other spurious instabilities can also arise and are documented herein. Areas of potential improvements in order to make the proposed methodology competitive with established approaches for global instability analysis are discussed.

  4. Integrated transcriptome and methylome analysis in youth at high risk for bipolar disorder: a preliminary analysis.

    Science.gov (United States)

    Fries, G R; Quevedo, J; Zeni, C P; Kazimi, I F; Zunta-Soares, G; Spiker, D E; Bowden, C L; Walss-Bass, C; Soares, J C

    2017-03-14

    First-degree relatives of patients with bipolar disorder (BD), particularly their offspring, have a higher risk of developing BD and other mental illnesses than the general population. However, the biological mechanisms underlying this increased risk are still unknown, particularly because most of the studies so far have been conducted in chronically ill adults and not in unaffected youth at high risk. In this preliminary study we analyzed genome-wide expression and methylation levels in peripheral blood mononuclear cells from children and adolescents from three matched groups: BD patients, unaffected offspring of bipolar parents (high risk) and controls (low risk). By integrating gene expression and DNA methylation and comparing the lists of differentially expressed genes and differentially methylated probes between groups, we were able to identify 43 risk genes that discriminate patients and high-risk youth from controls. Pathway analysis showed an enrichment of the glucocorticoid receptor (GR) pathway with the genes MED1, HSPA1L, GTF2A1 and TAF15, which might underlie the previously reported role of stress response in the risk for BD in vulnerable populations. Cell-based assays indicate a GR hyporesponsiveness in cells from adult BD patients compared to controls and suggest that these GR-related genes can be modulated by DNA methylation, which poses the theoretical possibility of manipulating their expression as a means to counteract the familial risk presented by those subjects. Although preliminary, our results suggest the utility of peripheral measures in the identification of biomarkers of risk in high-risk populations and further emphasize the potential role of stress and DNA methylation in the risk for BD in youth.

  5. Bioelectrical impedance analysis for bovine milk: Preliminary results

    Science.gov (United States)

    Bertemes-Filho, P.; Valicheski, R.; Pereira, R. M.; Paterno, A. S.

    2010-04-01

    This work reports the investigation and analysis of bovine milk quality by using biological impedance measurements using electrical impedance spectroscopy (EIS). The samples were distinguished by a first chemical analysis using Fourier transform midinfrared spectroscopy (FTIR) and flow citometry. A set of milk samples (100ml each) obtained from 17 different cows in lactation with and without mastitis were analyzed with the proposed technique using EIS. The samples were adulterated by adding distilled water and hydrogen peroxide in a controlled manner. FTIR spectroscopy and flow cytometry were performed, and impedance measurements were made in a frequency range from 500Hz up to 1MHz with an implemented EIS system. The system's phase shift was compensated by measuring saline solutions. It was possible to show that the results obtained with the Bioelectrical Impedance Analysis (BIA) technique may detect changes in the milk caused by mastitis and the presence of water and hydrogen peroxide in the bovine milk.

  6. A global optimization approach to multi-polarity sentiment analysis.

    Directory of Open Access Journals (Sweden)

    Xinmiao Li

    Full Text Available Following the rapid development of social media, sentiment analysis has become an important social media mining technique. The performance of automatic sentiment analysis primarily depends on feature selection and sentiment classification. While information gain (IG and support vector machines (SVM are two important techniques, few studies have optimized both approaches in sentiment analysis. The effectiveness of applying a global optimization approach to sentiment analysis remains unclear. We propose a global optimization-based sentiment analysis (PSOGO-Senti approach to improve sentiment analysis with IG for feature selection and SVM as the learning engine. The PSOGO-Senti approach utilizes a particle swarm optimization algorithm to obtain a global optimal combination of feature dimensions and parameters in the SVM. We evaluate the PSOGO-Senti model on two datasets from different fields. The experimental results showed that the PSOGO-Senti model can improve binary and multi-polarity Chinese sentiment analysis. We compared the optimal feature subset selected by PSOGO-Senti with the features in the sentiment dictionary. The results of this comparison indicated that PSOGO-Senti can effectively remove redundant and noisy features and can select a domain-specific feature subset with a higher-explanatory power for a particular sentiment analysis task. The experimental results showed that the PSOGO-Senti approach is effective and robust for sentiment analysis tasks in different domains. By comparing the improvements of two-polarity, three-polarity and five-polarity sentiment analysis results, we found that the five-polarity sentiment analysis delivered the largest improvement. The improvement of the two-polarity sentiment analysis was the smallest. We conclude that the PSOGO-Senti achieves higher improvement for a more complicated sentiment analysis task. We also compared the results of PSOGO-Senti with those of the genetic algorithm (GA and grid

  7. A Preliminary Analysis of a Behavioral Classrooms Needs Assessment

    Science.gov (United States)

    Leaf, Justin B.; Leaf, Ronald; McCray, Cynthia; Lamkins, Carol; Taubman, Mitchell; McEachin, John; Cihon, Joseph H.

    2016-01-01

    Today many special education classrooms implement procedures based upon the principles of Applied Behavior Analysis (ABA) to establish educationally relevant skills and decrease aberrant behaviors. However, it is difficult for school staff and consultants to evaluate the implementation of various components of ABA and general classroom set up. In…

  8. A Preliminary MANPRINT Evaluation of the All Source Analysis (ASAS)

    Science.gov (United States)

    1988-11-01

    Rear (CEWI) FSIC ............................ 2 CEWI ( TCAE ) AIM(6) ........................... 2 DTOC AIM(6...Sensors and the Ml Battalion TCAE ..... ............... . 13 2. Ratings of Understanding of Tasks Required at the Completion of Training and at the...for transmission to the sensors and jammers. CEWI Tactical Control and Analysis Element ( TCAE ) AIM(6) The AIM module consists of a VAX 750R computer

  9. TPX: Contractor preliminary design review. Volume 3, Design and analysis

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-30

    Several models have been formed for investigating the maximum electromagnetic loading and magnetic field levels associated with the Tokamak Physics eXperiment (TPX) superconducting Poloidal Field (PF) coils. The analyses have been performed to support the design of the individual fourteen hoop coils forming the PF system. The coils have been sub-divided into three coil systems consisting of the central solenoid (CS), PF5 coils, and the larger radius PF6 and PF7 coils. Various electromagnetic analyses have been performed to determine the electromagnetic loadings that the coils will experience during normal operating conditions, plasma disruptions, and fault conditions. The loadings are presented as net body forces acting individual coils, spatial variations throughout the coil cross section, and force variations along the path of the conductor due to interactions with the TF coils. Three refined electromagnetic models of the PF coil system that include a turn-by-turn description of the fields and forces during a worst case event are presented in this report. A global model including both the TF and PF system was formed to obtain the force variations along the path of the PF conductors resulting from interactions with the TF currents. In addition to spatial variations, the loadings are further subdivided into time-varying and steady components so that structural fatigue issues can be addressed by designers and analysts. Other electromagnetic design issues such as the impact of the detailed coil designs on field errors are addressed in this report. Coil features that are analyzed include radial transitions via short jogs vs. spiral type windings and the effects of layer-to-layer rotations (i.e clocking) on the field errors.

  10. A global sensitivity analysis approach for morphogenesis models

    KAUST Repository

    Boas, Sonja E. M.

    2015-11-21

    Background Morphogenesis is a developmental process in which cells organize into shapes and patterns. Complex, non-linear and multi-factorial models with images as output are commonly used to study morphogenesis. It is difficult to understand the relation between the uncertainty in the input and the output of such ‘black-box’ models, giving rise to the need for sensitivity analysis tools. In this paper, we introduce a workflow for a global sensitivity analysis approach to study the impact of single parameters and the interactions between them on the output of morphogenesis models. Results To demonstrate the workflow, we used a published, well-studied model of vascular morphogenesis. The parameters of this cellular Potts model (CPM) represent cell properties and behaviors that drive the mechanisms of angiogenic sprouting. The global sensitivity analysis correctly identified the dominant parameters in the model, consistent with previous studies. Additionally, the analysis provided information on the relative impact of single parameters and of interactions between them. This is very relevant because interactions of parameters impede the experimental verification of the predicted effect of single parameters. The parameter interactions, although of low impact, provided also new insights in the mechanisms of in silico sprouting. Finally, the analysis indicated that the model could be reduced by one parameter. Conclusions We propose global sensitivity analysis as an alternative approach to study the mechanisms of morphogenesis. Comparison of the ranking of the impact of the model parameters to knowledge derived from experimental data and from manipulation experiments can help to falsify models and to find the operand mechanisms in morphogenesis. The workflow is applicable to all ‘black-box’ models, including high-throughput in vitro models in which output measures are affected by a set of experimental perturbations.

  11. Preliminary shielding analysis for the CSNS target station monolith

    Institute of Scientific and Technical Information of China (English)

    张斌; 陈义学; 杨寿海; 吴军; 殷雯; 梁天骄; 贾学军

    2010-01-01

    The construction of the China Spallation Neutron Source (CSNS) has been initiated at Dongguan,Guangdong,China.In spallation neutron sources the target station monolith is contaminated by a large number of fast neutrons whose energies can be as large as those of the protons of the proton beam directed towards the tungsten target.A detailed radiation transport analysis of the target station monolith is important for the construction of the CSNS.The analysis is performed using the coupled Monte Carlo and multi-dimensional discrete ordinates method.Successful elimination of the primary ray effects via the two-dimensional uncollided flux and first collision source methodology is also illustrated.The dose at the edge of the monolith is calculated.The results demonstrate that the doses received by the hall staff members are below the required standard limit.

  12. Preliminary analysis of productivity of fruiting fungi on Strzeleckie meadows

    Directory of Open Access Journals (Sweden)

    Barbara Sadowska

    2014-11-01

    Full Text Available Analysis demonstrated that the fresh ahd dry weight as well as the ash content of fungal fruit bodies collected on a forest-surrounded unmown meadow (Stellario-Deschampsietum Freitag 1957 and Caricetum elatae W.Koch 1926 were lower than the same values for a plot of exploited mown meadow and higher than on an exploited unmown meadow (Arrhenatheretum medioeuropaeum (Br.-Bl. Oberd. 1952.

  13. Preliminary analysis of knee stress in Full Extension Landing

    Directory of Open Access Journals (Sweden)

    Majid Davoodi Makinejad

    2013-09-01

    Full Text Available OBJECTIVE: This study provides an experimental and finite element analysis of knee-joint structure during extended-knee landing based on the extracted impact force, and it numerically identifies the contact pressure, stress distribution and possibility of bone-to-bone contact when a subject lands from a safe height. METHODS: The impact time and loads were measured via inverse dynamic analysis of free landing without knee flexion from three different heights (25, 50 and 75 cm, using five subjects with an average body mass index of 18.8. Three-dimensional data were developed from computed tomography scans and were reprocessed with modeling software before being imported and analyzed by finite element analysis software. The whole leg was considered to be a fixed middle-hinged structure, while impact loads were applied to the femur in an upward direction. RESULTS: Straight landing exerted an enormous amount of pressure on the knee joint as a result of the body's inability to utilize the lower extremity muscles, thereby maximizing the threat of injury when the load exceeds the height-safety threshold. CONCLUSIONS: The researchers conclude that extended-knee landing results in serious deformation of the meniscus and cartilage and increases the risk of bone-to-bone contact and serious knee injury when the load exceeds the threshold safety height. This risk is considerably greater than the risk of injury associated with walking downhill or flexion landing activities.

  14. An interactive system for analysis of global cloud imagery

    Science.gov (United States)

    Woodberry, Karen; Tanaka, Ken; Hendon, Harry; Salby, Murry

    1991-01-01

    Synoptic images of the global cloud pattern composited from six contemporaneous satellites provide an unprecedented view of the global cloud field. Having horizontal resolution of about 0.5 deg and temporal resolution of 3 h, the global cloud imagery (GCI) resolves most of the variability of organized convection, including several harmonics of the diurnal cycle. Although the GCI has these attractive features, the dense and 3D nature of that data make it a formidable volume of information to treat in a practical and efficient manner. An interactive image-analysis system (IAS) has been developed to investigate the space-time variability of global cloud behavior. In the IAS, data, hardware, and software are integrated into a single system providing a variety of space-time covariance analyses in a menu-driven format. Owing to its customized architecture and certain homogeneous properties of the GCI, the IAS calculates such quantities effectively. Many covariance statistics are derived from 3D data with interactive speed, allowing the user to interrogate the archive iteratively in a single session. The 3D nature of those analyses and the speed with which they are performed distinguish the IAS from conventional image processing of 2D data.

  15. Simplifying multivariate survival analysis using global score test methodology

    Science.gov (United States)

    Zain, Zakiyah; Aziz, Nazrina; Ahmad, Yuhaniz

    2015-12-01

    In clinical trials, the main purpose is often to compare efficacy between experimental and control treatments. Treatment comparisons often involve multiple endpoints, and this situation further complicates the analysis of survival data. In the case of tumor patients, endpoints concerning survival times include: times from tumor removal until the first, the second and the third tumor recurrences, and time to death. For each patient, these endpoints are correlated, and the estimation of the correlation between two score statistics is fundamental in derivation of overall treatment advantage. In this paper, the bivariate survival analysis method using the global score test methodology is extended to multivariate setting.

  16. Global Analysis and Structural Performance of the Tubed Mega Frame

    OpenAIRE

    Zhang, Han

    2014-01-01

    The Tubed Mega Frame is a new structure concept for high-rise buildings which is developed by Tyréns. In order to study the structural performance as well as the efficiency of this new concept, a global analysis of the Tubed Mega Frame structure is performed using finite element analysis software ETABS. Besides, the lateral loads that should be applied on the structure according to different codes are also studied. From the design code study for wind loads and seismic design response spectrum...

  17. Global sensitivity analysis in stochastic simulators of uncertain reaction networks

    Science.gov (United States)

    Navarro Jimenez, M.; Le Maître, O. P.; Knio, O. M.

    2016-12-01

    Stochastic models of chemical systems are often subjected to uncertainties in kinetic parameters in addition to the inherent random nature of their dynamics. Uncertainty quantification in such systems is generally achieved by means of sensitivity analyses in which one characterizes the variability with the uncertain kinetic parameters of the first statistical moments of model predictions. In this work, we propose an original global sensitivity analysis method where the parametric and inherent variability sources are both treated through Sobol's decomposition of the variance into contributions from arbitrary subset of uncertain parameters and stochastic reaction channels. The conceptual development only assumes that the inherent and parametric sources are independent, and considers the Poisson processes in the random-time-change representation of the state dynamics as the fundamental objects governing the inherent stochasticity. A sampling algorithm is proposed to perform the global sensitivity analysis, and to estimate the partial variances and sensitivity indices characterizing the importance of the various sources of variability and their interactions. The birth-death and Schlögl models are used to illustrate both the implementation of the algorithm and the richness of the proposed analysis method. The output of the proposed sensitivity analysis is also contrasted with a local derivative-based sensitivity analysis method classically used for this type of systems.

  18. Global sensitivity analysis in stochastic simulators of uncertain reaction networks

    KAUST Repository

    Navarro Jimenez, M.

    2016-12-26

    Stochastic models of chemical systems are often subjected to uncertainties in kinetic parameters in addition to the inherent random nature of their dynamics. Uncertainty quantification in such systems is generally achieved by means of sensitivity analyses in which one characterizes the variability with the uncertain kinetic parameters of the first statistical moments of model predictions. In this work, we propose an original global sensitivity analysis method where the parametric and inherent variability sources are both treated through Sobol’s decomposition of the variance into contributions from arbitrary subset of uncertain parameters and stochastic reaction channels. The conceptual development only assumes that the inherent and parametric sources are independent, and considers the Poisson processes in the random-time-change representation of the state dynamics as the fundamental objects governing the inherent stochasticity. A sampling algorithm is proposed to perform the global sensitivity analysis, and to estimate the partial variances and sensitivity indices characterizing the importance of the various sources of variability and their interactions. The birth-death and Schlögl models are used to illustrate both the implementation of the algorithm and the richness of the proposed analysis method. The output of the proposed sensitivity analysis is also contrasted with a local derivative-based sensitivity analysis method classically used for this type of systems.

  19. Solar Neutrinos with Magnetic Moment Rates and Global Analysis

    CERN Document Server

    Pulido, J

    2002-01-01

    A statistical analysis of the solar neutrino data is presented assuming the solar neutrino deficit to be resolved by the resonant interaction of the neutrino magnetic moment with the solar magnetic field. Four field profiles are investigated, all exhibiting a rapid increase across the bottom of the convective zone, one of them closely following the requirements from recent solar physics investigations. First a 'rates only' analysis is performed whose best fits appear to be remarkably better than all fits from oscillations. A global analysis then follows with the corresponding best fits of a comparable quality to the LMA one. Despite the fact that the resonant spin flavour precession does not predict any day/night effect, the separate SuperKamiokande day and night data are included in the analysis in order to allow for a direct comparison with oscillation scenarios. Remarkably enough, the best fit for rates and global analysis which is compatible with most astrophysical bounds on the neutrino magnetic moment i...

  20. Global sensitivity analysis in stochastic simulators of uncertain reaction networks.

    Science.gov (United States)

    Navarro Jimenez, M; Le Maître, O P; Knio, O M

    2016-12-28

    Stochastic models of chemical systems are often subjected to uncertainties in kinetic parameters in addition to the inherent random nature of their dynamics. Uncertainty quantification in such systems is generally achieved by means of sensitivity analyses in which one characterizes the variability with the uncertain kinetic parameters of the first statistical moments of model predictions. In this work, we propose an original global sensitivity analysis method where the parametric and inherent variability sources are both treated through Sobol's decomposition of the variance into contributions from arbitrary subset of uncertain parameters and stochastic reaction channels. The conceptual development only assumes that the inherent and parametric sources are independent, and considers the Poisson processes in the random-time-change representation of the state dynamics as the fundamental objects governing the inherent stochasticity. A sampling algorithm is proposed to perform the global sensitivity analysis, and to estimate the partial variances and sensitivity indices characterizing the importance of the various sources of variability and their interactions. The birth-death and Schlögl models are used to illustrate both the implementation of the algorithm and the richness of the proposed analysis method. The output of the proposed sensitivity analysis is also contrasted with a local derivative-based sensitivity analysis method classically used for this type of systems.

  1. Preliminary analysis of the mitochondrial genome evolutionary pattern in primates

    Institute of Scientific and Technical Information of China (English)

    Liang ZHAO; Xingtao ZHANG; Xingkui TAO; Weiwei WANG; Ming LI

    2012-01-01

    Since the birth of molecular evolutionary analysis,primates have been a central focus of study and mitochondrial DNA is well suited to these endeavors because of its unique features.Surprisingly,to date no comprehensive evaluation of the nucleotide substitution patterns has been conducted on the mitochondrial genome of primates.Here,we analyzed the evolutionary patterns and evaluated selection and recombination in the mitochondrial genomes of 44 Primates species downloaded from GenBank.The results revealed that a strong rate heterogeneity occurred among sites and genes in all comparisons.Likewise,an obvious decline in primate nucleotide diversity was noted in the subunit rRNAs and tRNAs as compared to the protein-coding genes.Within 13 protein-coding genes,the pattern of nonsynonymous divergence was similar to that of overall nucleotide divergence,while synonymous changes differed only for individual genes,indicating that the rate heterogeneity may result from the rate of change at nonsynonymous sites.Codon usage analysis revealed that there was intermediate codon usage bias in primate protein-coding genes,and supported the idea that GC mutation pressure might determine codon usage and that positive selection is not the driving force for the codon usage bias.Neutrality tests using site-specific positive selection from a Bayesian framework indicated no sites were under positive selection for any gene,consistent with near neutrality.Recombination tests based on the pairwise homoplasy test statistic supported complete linkage even for much older divergent primate species.Thus,with the exception of rate heterogeneity among mitochondrial genes,evaluating the validity assumed complete linkage and selective neutrality in primates prior to phylogenetic or phylogeographic analysis seems unnecessary.

  2. Preliminary analysis of the mitochondrial genome evolutionary pattern in primates.

    Science.gov (United States)

    Zhao, Liang; Zhang, Xingtao; Tao, Xingkui; Wang, Weiwei; Li, Ming

    2012-08-01

    Since the birth of molecular evolutionary analysis, primates have been a central focus of study and mitochondrial DNA is well suited to these endeavors because of its unique features. Surprisingly, to date no comprehensive evaluation of the nucleotide substitution patterns has been conducted on the mitochondrial genome of primates. Here, we analyzed the evolutionary patterns and evaluated selection and recombination in the mitochondrial genomes of 44 Primates species downloaded from GenBank. The results revealed that a strong rate heterogeneity occurred among sites and genes in all comparisons. Likewise, an obvious decline in primate nucleotide diversity was noted in the subunit rRNAs and tRNAs as compared to the protein-coding genes. Within 13 protein-coding genes, the pattern of nonsynonymous divergence was similar to that of overall nucleotide divergence, while synonymous changes differed only for individual genes, indicating that the rate heterogeneity may result from the rate of change at nonsynonymous sites. Codon usage analysis revealed that there was intermediate codon usage bias in primate protein-coding genes, and supported the idea that GC mutation pressure might determine codon usage and that positive selection is not the driving force for the codon usage bias. Neutrality tests using site-specific positive selection from a Bayesian framework indicated no sites were under positive selection for any gene, consistent with near neutrality. Recombination tests based on the pairwise homoplasy test statistic supported complete linkage even for much older divergent primate species. Thus, with the exception of rate heterogeneity among mitochondrial genes, evaluating the validity assumed complete linkage and selective neutrality in primates prior to phylogenetic or phylogeographic analysis seems unnecessary.

  3. Preliminary safety analysis for key design features of KALIMER-600

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Y. B.; Chang, W. P.; Suk, S. D.; Ha, K. S.; Jeong, H. Y.; Heo, S

    2004-03-01

    KAERI is developing the conceptual design of a Liquid Metal Reactor, KALIMER-600 (Korea Advanced LIquid MEtal Reactor) under the Long-term Nuclear R and D Program. KALIMER-600 addresses key issues regarding future nuclear power plants such as plant safety, economics, proliferation, and waste. In this report, key safety design features are described and safety analyses results for typical ATWS accidents in the KALIMER design with breakeven core are presented. First, the basic approach to achieve the safety goal is introduced in Chapter 1, and the event categorization and acceptance criteria for the KALIMER-600 safety analysis are described in Chapter 2. In Chapter 3, results of inherent safety evaluations for the KALIMER-600 conceptual design are presented. The KALIMER-600 core and plant system are designed to assure benign performance during a selected set of events without either reactor control or protection system intervention. Safety analyses for the postulated Anticipated Transient Without Scram (ATWS) have been performed using the SSC-K code to investigate the KALIMER-600 system response to the events. They are categorized as Bounding Events (BEs) because of their low probability of occurrence. In Chapter 4, the analysis of flow blockage for KALIMER-600 with the MATRA-LMR-FB code, which has been developed for the internal flow blockage in a LMR subassembly. The cases with a blockage of 6-subchannel, 24-subchannel, and 54-subchannel are analyzed.The performance analysis of the KALIMER-600 containment and some evaluations for the behaviors during HCDA will be performed later.

  4. Preliminary safety analysis for key design features of KALIMER

    Energy Technology Data Exchange (ETDEWEB)

    Hahn, D. H.; Kwon, Y. M.; Chang, W. P.; Suk, S. D.; Lee, S. O.; Lee, Y. B.; Jeong, K. S

    2000-07-01

    KAERI is currently developing the conceptual design of a liquid metal reactor, KALIMER(Korea Advanced Liquid Metal Reactor) under the long-term nuclear R and D program. In this report, descriptions of the KALIMER safety design features and safety analyses results for selected ATWS accidents are presented. First, the basic approach to achieve the safety goal is introduced in chapter 1, and the safety evaluation procedure for the KALIMER design is described in chapter 2. It includes event selection, event categorization, description of design basis events, and beyond design basis events. In chapter 3, results of inherent safety evaluations for the KALIMER conceptual design are presented. The KALIMER core and plant system are designed to assure design performance during a selected set of events without either reactor control or protection system intervention. Safety analyses for the postulated anticipated transient without scram(ATWS) have been performed to investigate the KALIMER system response to the events. They are categorized as bounding events(BEs) because of their low probability of occurrence. In chapter 4, the design of the KALIMER containment dome and the results of its performance analysis are presented. The designs of the existing LMR containment and the KALIMER containment dome have been compared in this chapter. Procedure of the containment performance analysis and the analysis results are described along with the accident scenario and source terms. Finally, a simple methodology is introduced to investigate the core kinetics and hydraulic behavior during HCDA in chapter 5. Mathematical formulations have been developed in the framework of the modified bethe-tait method, and scoping analyses have been performed for the KALIMER core behavior during super-prompt critical excursions.

  5. Preliminary RAMI analysis of DFLL TBS for ITER

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Dagui [Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei, Anhui, 230031 (China); University of Science and Technology of China, Hefei, Anhui, 230031 (China); Yuan, Run [Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei, Anhui, 230031 (China); Wang, Jiaqun, E-mail: jiaqun.wang@fds.org.cn [Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei, Anhui, 230031 (China); Wang, Fang; Wang, Jin [Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei, Anhui, 230031 (China)

    2016-11-15

    Highlights: • We performed the functional analysis of the DFLL TBS. • We performed a failure mode analysis of the DFLL TBS. • We estimated the reliability and availability of the DFLL TBS. • The ITER RAMI approach was applied to the DFLL TBS for technical risk control in the design phase. - Abstract: ITER is the first fusion machine fully designed to prove the physics and technological basis for next fusion power plants. Among the main technical objectives of ITER is to test and validate design concepts of tritium breeding blankets relevant to the fusion power plants. To achieve this goal, China has proposed the dual functional lithium-lead test blanket module (DFLL TBM) concept design. The DFLL TBM and its associated ancillary system were called DFLL TBS. The DFLL TBS play a key role in next fusion reactor. In order to ensure reliable and available of DFLL TBS, the risk control project of DFLL TBS has been put on the schedule. As the stage of the ITER technical risk control policy, the RAMI (Reliability, Availability, Maintainability, Inspectability) approach was used to control the technical risk of ITER. In this paper, the RAMI approach was performed on the conceptual design of DFLL TBS. A functional breakdown was prepared on DFLL TBS, and the system was divided into 3 main functions and 72 basic functions. Based on the result of functional breakdown of DFLL TBS, the reliability block diagrams were prepared to estimate the reliability and availability of each function under the stipulated operating conditions. The inherent availability of the DFLL TBS expected after implementation of mitigation actions was calculated to be 98.57% over 2 years based on the ITER reliability database. A Failure Modes Effects and Criticality Analysis (FMECA) was performed with criticality charts highlighting the risk level of the different failure modes with regard to their probability of occurrence and their effects on the availability.

  6. Macroalgae as a Biomass Feedstock: A Preliminary Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Roesijadi, Guritno; Jones, Susanne B.; Snowden-Swan, Lesley J.; Zhu, Yunhua

    2010-09-26

    A thorough of macroalgae analysis as a biofuels feedstock is warranted due to the size of this biomass resource and the need to consider all potential sources of feedstock to meet current biomass production goals. Understanding how to harness this untapped biomass resource will require additional research and development. A detailed assessment of environmental resources, cultivation and harvesting technology, conversion to fuels, connectivity with existing energy supply chains, and the associated economic and life cycle analyses will facilitate evaluation of this potentially important biomass resource.

  7. Statistical Analysis of Time Series Data (STATS). Users Manual (Preliminary)

    Science.gov (United States)

    1987-05-01

    15, 30. 60, 90, 120, andL -!/14:X.... 183 days are presently used. auto Page 1 of 10 wrpy *VtsE0> J1 record (continued) Field Variab Vlue D 2 NPRDS ...each event. 6 JEND + Order number of last period in time series to ( NPRDS ) select for analysis. If blank, the last period is assumed. 7 JPPF Plotting...values. 2 NPRDS + Actual number of periods for the event following on ’INO records until the next ID, BF, or LI record. IN record - T:E SERIES DATA

  8. A preliminary study of the impact of the ERS 1 C band scatterometer wind data on the European Centre for Medium-Range Weather Forecasts global data assimilation system

    Science.gov (United States)

    Hoffman, Ross N.

    1993-01-01

    A preliminary assessment of the impact of the ERS 1 scatterometer wind data on the current European Centre for Medium-Range Weather Forecasts analysis and forecast system has been carried out. Although the scatterometer data results in changes to the analyses and forecasts, there is no consistent improvement or degradation. Our results are based on comparing analyses and forecasts from assimilation cycles. The two sets of analyses are very similar except for the low level wind fields over the ocean. Impacts on the analyzed wind fields are greater over the southern ocean, where other data are scarce. For the most part the mass field increments are too small to balance the wind increments. The effect of the nonlinear normal mode initialization on the analysis differences is quite small, but we observe that the differences tend to wash out in the subsequent 6-hour forecast. In the Northern Hemisphere, analysis differences are very small, except directly at the scatterometer locations. Forecast comparisons reveal large differences in the Southern Hemisphere after 72 hours. Notable differences in the Northern Hemisphere do not appear until late in the forecast. Overall, however, the Southern Hemisphere impacts are neutral. The experiments described are preliminary in several respects. We expect these data to ultimately prove useful for global data assimilation.

  9. A Preliminary Genetic Analysis of Complement 3 Gene and Schizophrenia.

    Directory of Open Access Journals (Sweden)

    Jianliang Ni

    Full Text Available Complement pathway activation was found to occur frequently in schizophrenia, and complement 3 (C3 plays a major role in this process. Previous studies have provided evidence for the possible role of C3 in the development of schizophrenia. In this study, we hypothesized that the gene encoding C3 (C3 may confer susceptibility to schizophrenia in Han Chinese. We analyzed 7 common single nucleotide polymorphisms (SNPs of C3 in 647 schizophrenia patients and 687 healthy controls. Peripheral C3 mRNA expression level was measured in 23 drug-naïve patients with schizophrenia and 24 controls. Two SNPs (rs1047286 and rs2250656 that deviated from Hardy-Weinberg equilibrium were excluded for further analysis. Among the remaining 5 SNPs, there was no significant difference in allele and genotype frequencies between the patient and control groups. Logistic regression analysis showed no significant SNP-gender interaction in either dominant model or recessive model. There was no significant difference in the level of peripheral C3 expression between the drug-naïve schizophrenia patients and healthy controls. In conclusion, the results of this study do not support C3 as a major genetic susceptibility factor in schizophrenia. Other factors in AP may have critical roles in schizophrenia and be worthy of further investigation.

  10. Preliminary Rock Physics Analysis on Lodgepole Formation in Manitoba, Canada

    Science.gov (United States)

    Kim, N.; Keehm, Y.

    2012-12-01

    We present rock physics analysis results of Lodgepole Formation, a carbonate reservoir in Daly Field, Manitoba, Canada. We confirmed that the Lodgepole Formation can be divided into six units in the study area: Basal Limestone, Cromer Shale, Cruickshank Crinoidal, Cruickshank Shale, Daly member and Flossie Lake member from the bottom, using eight well log data and previous works. We then performed rock physics analyses on four carbonate units (Basal Limestone, Cruickshank Crinoidal, Daly and Flossie Lake), such as Vp-porosity, AI-porosity, DEM (differential effective medium) modeling, and fluid substitution analysis. In Vp-porosity domain, the top unit, Flossie Lake member has lower porosity and higher velocity, while the other units show similar porosity and velocity. We think that this results from the diagenesis of Flossie Lake member since it bounds with unconformity. However, the four units show very similar trend in Vp-porosity domain, and we can report one Vp-porosity relation for all carbonate units of the Lodgepole formation. We also found that the acoustic impedance varies more than 10% from low porosity zone (3-6%) to high porosity zone (9-12%) from AI-porosity analysis. Thus one can delineate high porosity zone from seismic impedance data. DEM modeling showed that Flossie Lake would have relatively low aspect ratio of pores than the others, which implies that the top unit has been influenced by diagenesis. To determine fluid sensitivity of carbonate units, we conducted fluid substitution on four units from 100% water to 100% oil. The top unit, Flossie Lake, showed slight increase of Vp, which seems to be density effect. The others showed small decrease of Vp, but not significant. If we observe Vp/Vs rather than Vp, the sensitivity increases. However, fluid discrimination would be difficult because of high stiffness of rock frame. In summary, three lower carbonate units of Lodgepole Formation would be prospective and high porosity zone can be delineated

  11. Brain hemisphere dominance and vocational preference: a preliminary analysis.

    Science.gov (United States)

    Szirony, Gary Michael; Pearson, L Carolyn; Burgin, John S; Murray, Gerald C; Elrod, Lisa Marie

    2007-01-01

    Recent developments in split-brain theory add support to the concept of specialization within brain hemispheres. Holland's vocational personality theory may overlap with Human Information Processing (HIP) characteristics. Holland's six RIASEC codes were developed to identify vocational personality characteristics, and HIP scales were designed to measure hemispheric laterality. Relationships between the two scales were evaluated through canonical correlation with some significant results, however not all Holland scale scores correlated with left, right, or integrated hemispheric preference. Additional findings related to participants self-perception of music and math ability were also correlated. Findings on this added analysis revealed a high correlation between perception of musical ability and right brain function but not between mathematical concept and left brain alone. Implications regarding vocational choice and work are discussed.

  12. City of Hoboken Energy Surety Analysis: Preliminary Design Summary

    Energy Technology Data Exchange (ETDEWEB)

    Stamp, Jason Edwin [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Military and Energy Systems Analysis Dept.; Baca, Michael J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Military and Energy Systems Analysis Dept.; Munoz-Ramos, Karina [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Military and Energy Systems Analysis Dept.; Schenkman, Benjamin L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Military and Energy Systems Analysis Dept.; Eddy, John P. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Systems Readiness and Sustainment Technology Dept.; Smith, Mark A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Systems Readiness and Sustainment Technology Dept.; Guttromson, Ross [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Electric Power Systems Research Dept.; Henry, Jordan M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Critical Infrastructure Systems Dept.; Jensen, Richard Pearson [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Geomechanics Dept.

    2014-09-01

    In 2012, Hurricane Sandy devastated much of the U.S. northeast coastal areas. Among those hardest hit was the small community of Hoboken, New Jersey, located on the banks of the Hudson River across from Manhattan. This report describes a city-wide electrical infrastructure design that uses microgrids and other infrastructure to ensure the city retains functionality should such an event occur in the future. The designs ensure that up to 55 critical buildings will retain power during blackout or flooded conditions and include analysis for microgrid architectures, performance parameters, system control, renewable energy integration, and financial opportunities (while grid connected). The results presented here are not binding and are subject to change based on input from the Hoboken stakeholders, the integrator selected to manage and implement the microgrid, or other subject matter experts during the detailed (final) phase of the design effort.

  13. Analysis of organochlorine pesticides in human milk: preliminary results.

    Science.gov (United States)

    Campoy, C; Jiménez, M; Olea-Serrano, M F; Moreno-Frías, M; Cañabate, F; Olea, N; Bayés, R; Molina-Font, J A

    2001-11-01

    In the face of evidence of human milk contamination by organochlorine pesticides, an analysis was performed on samples of milk obtained from healthy lactating women in the provinces of Granada and Almeria in Southern Spain. The samples were obtained by the Neonate Section of the Department of Pediatrics of Granada University Hospital (Neonatology Division) and by the Neonatal Service of Poniente Hospital in El Ejido, Almería. A liquid-liquid extraction procedure was performed. The cleaning of the sample before gas chromatography-mass spectrometry (GC-MS) used silica Sep-Pak. Among other pesticides, aldrin, dieldrin, DDT and its metabolites, lindane, methoxychlor and endosulfan were identified. The presence of these products was confirmed by mass spectrometry. The identification and quantification of these organochlorine molecules is important because they have estrogenic effects.

  14. Global lateral buckling analysis of idealized subsea pipelines

    Institute of Scientific and Technical Information of China (English)

    刘润; 刘文彬; 吴新利; 闫澍旺

    2014-01-01

    In order to avoid the curing effects of paraffin on the transport process and reduce the transport difficulty, usually high temperature and high pressure are used in the transportation of oil and gas. The differences of temperature and pressure cause additional stress along the pipeline, due to the constraint of the foundation soil, the additional stress can not release freely, when the additional stress is large enough to motivate the submarine pipelines buckle. In this work, the energy method is introduced to deduce the analytical solution which is suitable for the global buckling modes of idealized subsea pipeline and analyze the relationship between the critical buckling temperature, buckling length and amplitude under different high-order global lateral buckling modes. To obtain a consistent formulation of the problem, the principles of virtual displacements and the variation calculus for variable matching points are applied. The finite element method based on elasto-plastic theory is used to simulate the lateral global buckling of the pipelines under high temperature and pressure. The factors influencing the lateral buckling of pipelines are further studied. Based upon some actual engineering projects, the finite element results are compared with the analytical ones, and then the influence of thermal stress, the section rigidity of pipeline, the soil properties and the trigging force to the high order lateral buckling are discussed. The method of applying the small trigging force on pipeline is reliable in global buckling numerical analysis. In practice, increasing the section rigidity of a pipeline is an effective measure to improve the ability to resist the global buckling.

  15. Preliminary Analysis of a Fully Solid State Magnetocaloric Refrigeration

    Energy Technology Data Exchange (ETDEWEB)

    Abdelaziz, Omar [ORNL

    2016-01-01

    Magnetocaloric refrigeration is an alternative refrigeration technology with significant potential energy savings compared to conventional vapor compression refrigeration technology. Most of the reported active magnetic regenerator (AMR) systems that operate based on the magnetocaloric effect use heat transfer fluid to exchange heat, which results in complicated mechanical subsystems and components such as rotating valves and hydraulic pumps. In this paper, we propose an alternative mechanism for heat transfer between the AMR and the heat source/sink. High-conductivity moving rods/sheets (e.g. copper, brass, iron, graphite, aluminum or composite structures from these) are utilized instead of heat transfer fluid significantly enhancing the heat transfer rate hence cooling/heating capacity. A one-dimensional model is developed to study the solid state AMR. In this model, the heat exchange between the solid-solid interfaces is modeled via a contact conductance, which depends on the interface apparent pressure, material hardness, thermal conductivity, surface roughness, surface slope between the interfaces, and material filled in the gap between the interfaces. Due to the tremendous impact of the heat exchange on the AMR cycle performance, a sensitivity analysis is conducted employing a response surface method, in which the apparent pressure, effective surface roughness and grease thermal conductivity are the uncertainty factors. COP and refrigeration capacity are presented as the response in the sensitivity analysis to reveal the important factors influencing the fully solid state AMR and optimize the solid state AMR efficiency. The performances of fully solid state AMR and traditional AMR are also compared and discussed in present work. The results of this study will provide general guidelines for designing high performance solid state AMR systems.

  16. Preliminary analysis of cerebrospinal fluid proteome in patients with neurocysticercosis

    Institute of Scientific and Technical Information of China (English)

    TIAN Xiao-jun; LI Jing-yi; HUANG Yong; XUE Yan-ping

    2009-01-01

    Background Neurocysticercosis is the infection of the nervous system by the larvae of Taenia solium (T. solium). Despite continuous effort, the experimental diagnosis of neurocysticercosis remains unresolved. Since the cerebrospinal fluid (CSF) contacts with the brain, dynamic information about pathological processes of the brain is likely to be reflected in CSF. Therefore, CSF may serve as a rich source of putative biomarkers related to neurocysticercosis. Comparative proteomic analysis of CSF of neurocysticercosis patients and control subjects may find differentially expressed proteins. Methods Two-dimensional difference in gel electrophoresis (2D-DIGE) was used to investigate differentially expressed proteins in CSF of patients with neurocysticercosis by comparing the protein profile of CSF from neurocysticercosis patients with that from control subjects. The differentially expressed spots/proteins were recognized with matrix-assisted laser desorption/ionization-time of flight-time of flight (MALDI-TOF-TOF) mass spectrometry. Results Forty-four enzyme digested peptides were obtained from 4 neurocysticercotic patients. Twenty-three were identified through search of the NCBI protein database with Mascot software, showing 19 up-expressed and 4 down-expressed. Of these proteins, 26S proteosome related to ATP- and ubiquitin-dependent degradation of proteins and lipocalin type prostaglandin D synthase involved in PGD2-synthesis and extracellular transporter activities were up-expressed, while transferrin related to iron metabolism within the brain was down-expressed. Conclusions This study established the proteomic profile of pooled CSF from 4 patients with neurocysticercosis, suggesting the potential value of proteomic analysis for the study of candidate biomarkers involved in the diagnosis or pathogenesis of neurocysticercosis.

  17. Preliminary Design and Analysis of the GIFTS Instrument Pointing System

    Science.gov (United States)

    Zomkowski, Paul P.

    2003-01-01

    The Geosynchronous Imaging Fourier Transform Spectrometer (GIFTS) Instrument is the next generation spectrometer for remote sensing weather satellites. The GIFTS instrument will be used to perform scans of the Earth s atmosphere by assembling a series of field-of- views (FOV) into a larger pattern. Realization of this process is achieved by step scanning the instrument FOV in a contiguous fashion across any desired portion of the visible Earth. A 2.3 arc second pointing stability, with respect to the scanning instrument, must be maintained for the duration of the FOV scan. A star tracker producing attitude data at 100 Hz rate will be used by the autonomous pointing algorithm to precisely track target FOV s on the surface of the Earth. The main objective is to validate the pointing algorithm in the presence of spacecraft disturbances and determine acceptable disturbance limits from expected noise sources. Proof of concept validation of the pointing system algorithm is carried out with a full system simulation developed using Matlab Simulink. Models for the following components function within the full system simulation: inertial reference unit (IRU), attitude control system (ACS), reaction wheels, star tracker, and mirror controller. With the spacecraft orbital position and attitude maintained to within specified limits the pointing algorithm receives quaternion, ephemeris, and initialization data that are used to construct the required mirror pointing commands at a 100 Hz rate. This comprehensive simulation will also aid in obtaining a thorough understanding of spacecraft disturbances and other sources of pointing system errors. Parameter sensitivity studies and disturbance analysis will be used to obtain limits of operability for the GIFTS instrument. The culmination of this simulation development and analysis will be used to validate the specified performance requirements outlined for this instrument.

  18. Preliminary analysis of the use of smartwatches for longitudinal health monitoring.

    Science.gov (United States)

    Jovanov, Emil

    2015-08-01

    New generations of smartwatches feature continuous measurement of physiological parameters, such as heart rate, galvanic skin resistance (GSR), and temperature. In this paper we present the results of preliminary analysis of the use of Basis Peak smartwatch for longitudinal health monitoring during a 4 month period. Physiological measurements during sleep are validated using Zephyr Bioharness 3 monitor and SOMNOscreen+ polysomnographic monitoring system from SOMNOmedics. Average duration of sequences with no missed data was 49.9 minutes, with maximum length of 17 hours, and they represent 88.88% of recording time. Average duration of the charging event was 221.9 min, and average time between charges was 54 hours, with maximum duration of the charging event of 16.3 hours. Preliminary results indicate that the physiological monitoring performance of existing smartwatches provides sufficient performance for longitudinal monitoring of health status and analysis of health and wellness trends.

  19. Relative risk analysis in regulating the use of radiation-emitting medical devices. A preliminary application

    Energy Technology Data Exchange (ETDEWEB)

    Jones, E.D.; Banks, W.W.; Altenbach, T.J.; Fischer, L.E. [Lawrence Livermore National Lab., CA (United States)

    1995-09-01

    This report describes a preliminary application of an analysis approach for assessing relative risks in the use of radiation- emitting medical devices. Results are presented on human-initiated actions and failure modes that are most likely to occur in the use of the Gamma Knife, a gamma irradiation therapy device. This effort represents an initial step in a US Nuclear Regulatory Commission (NRC) plan to evaluate the potential role of risk analysis in regulating the use of nuclear medical devices. For this preliminary application of risk assessment, the focus was to develop a basic process using existing techniques for identifying the most likely risk contributors and their relative importance. The approach taken developed relative risk rankings and profiles that incorporated the type and quality of data available and could present results in an easily understood form. This work was performed by the Lawrence Livermore National Laboratory for the NRC.

  20. Globalization and Shanghai Model: A Retrospective and Prospective Analysis

    OpenAIRE

    Linsun Cheng

    2012-01-01

    Intended to shed light on the debate on the results of globalization and providebetter understanding of the influences of globalization upon China as well as theworld, this article traces the history of Shanghai’s economic globalization over thepast 170 years since 1843 and demonstrates the benefits and problems Shanghaireceived from (or connected to) its economic globalization. Divided into threesections (Globalization, de-globalization and re-globalization of Shanghai’s economy;Manufacturin...

  1. A Preliminary Tsunami Vulnerability Analysis for Yenikapi Region in Istanbul

    Science.gov (United States)

    Ceren Cankaya, Zeynep; Suzen, Lutfi; Cevdet Yalciner, Ahmet; Kolat, Cagil; Aytore, Betul; Zaytsev, Andrey

    2015-04-01

    One of the main requirements during post disaster recovery operations is to maintain proper transportation and fluent communication at the disaster areas. Ports and harbors are the main transportation hubs which must work with proper performance at all times especially after the disasters. Resilience of coastal utilities after earthquakes and tsunamis have major importance for efficient and proper rescue and recovery operations soon after the disasters. Istanbul is a mega city with its various coastal utilities located at the north coast of the Sea of Marmara. At Yenikapi region of Istanbul, there are critical coastal utilities and vulnerable coastal structures and critical activities occur daily. Fishery ports, commercial ports, small craft harbors, passenger terminals of intercity maritime transportation, water front commercial and/or recreational structures are some of the examples of coastal utilization which are vulnerable against marine disasters. Therefore their vulnerability under tsunami or any other marine hazard to Yenikapi region of Istanbul is an important issue. In this study, a methodology of vulnerability analysis under tsunami attack is proposed with the applications to Yenikapi region. In the study, high resolution (1m) GIS database of Istanbul Metropolitan Municipality (IMM) is used and analyzed by using GIS implementation. The bathymetry and topography database and the vector dataset containing all buildings/structures/infrastructures in the study area are obtained for tsunami numerical modeling for the study area. GIS based tsunami vulnerability assessment is conducted by applying the Multi-criteria Decision Making Analysis (MCDA). The tsunami parameters from deterministically defined worst case scenarios are computed from the simulations using tsunami numerical model NAMI DANCE. The vulnerability parameters in the region due to two different classifications i) vulnerability of buildings/structures and ii) vulnerability of (human) evacuation

  2. Global tractography with embedded anatomical priors for quantitative connectivity analysis

    Directory of Open Access Journals (Sweden)

    Alia eLemkaddem

    2014-11-01

    Full Text Available The main assumption of fiber-tracking algorithms is that fiber trajectories are represented by paths of highest diffusion, which is usually accomplished by following the principal diffusion directions estimated in every voxel from the measured diffusion MRI data. The state-of-the-art approaches, known as global tractography, reconstruct all the fiber tracts of the whole brain simultaneously by solving a global energy minimization problem. The tractograms obtained with these algorithms outperform any previous technique but, unfortunately, the price to pay is an increased computational cost which is not suitable in many practical settings, both in terms of time and memory requirements. Furthermore, existing global tractography algorithms suffer from an important shortcoming that is crucial in the context of brain connectivity analyses. As no anatomical priors are used during in the reconstruction process, the recovered fiber tracts are not guaranteed to connect cortical regions and, as a matter of fact, most of them stop prematurely in the white matter. This does not only unnecessarily slow down the estimation procedure and potentially biases any subsequent analysis but also, most importantly, prevents the de facto quantification of brain connectivity. In this work, we propose a novel approach for global tractography that is specifically designed for connectivity analysis applications by explicitly enforcing anatomical priors of the tracts in the optimization and considering the effective contribution of each of them, i.e. volume, to the acquired diffusion MRI image. We evaluated our approach on both a realistic diffusion MRI phantom and in-vivo data, and also compared its performance to existing tractography aloprithms.

  3. A simplified procedure of linear regression in a preliminary analysis

    Directory of Open Access Journals (Sweden)

    Silvia Facchinetti

    2013-05-01

    Full Text Available The analysis of a statistical large data-set can be led by the study of a particularly interesting variable Y – regressed – and an explicative variable X, chosen among the remained variables, conjointly observed. The study gives a simplified procedure to obtain the functional link of the variables y=y(x by a partition of the data-set into m subsets, in which the observations are synthesized by location indices (mean or median of X and Y. Polynomial models for y(x of order r are considered to verify the characteristics of the given procedure, in particular we assume r= 1 and 2. The distributions of the parameter estimators are obtained by simulation, when the fitting is done for m= r + 1. Comparisons of the results, in terms of distribution and efficiency, are made with the results obtained by the ordinary least square methods. The study also gives some considerations on the consistency of the estimated parameters obtained by the given procedure.

  4. Preliminary Analysis of Slope Stability in Kuok and Surrounding Areas

    Directory of Open Access Journals (Sweden)

    Dewandra Bagus Eka Putra

    2016-12-01

    Full Text Available The level of slope influenced by the condition of the rocks beneath the surface. On high level of slopes, amount of surface runoff and water transport energy is also enlarged. This caused by greater gravity, in line with the surface tilt from the horizontal plane. In other words, topsoil eroded more and more. When the slope becomes twice as steep, then the amount of erosion per unit area be 2.0 - 2.5 times more. Kuok and surrounding area is the road access between the West Sumatra and Riau which plays an important role economies of both provinces. The purpose of this study is to map the locations that have fairly steep slopes and potential mode of landslides. Based on SRTM data obtained,  the roads in Kuok area has a minimum elevation of + 33 m and a maximum  + 217.329 m. Rugged road conditions with slope ranging from 24.08 ° to 44.68 ° causing this area having frequent landslides. The result of slope stability analysis in a slope near the Water Power Plant Koto Panjang, indicated that mode of active failure is toppling failure or rock fall and the potential zone of failure is in the center part of the slope.

  5. Social network analysis in identifying influential webloggers: A preliminary study

    Science.gov (United States)

    Hasmuni, Noraini; Sulaiman, Nor Intan Saniah; Zaibidi, Nerda Zura

    2014-12-01

    In recent years, second generation of internet-based services such as weblog has become an effective communication tool to publish information on the Web. Weblogs have unique characteristics that deserve users' attention. Some of webloggers have seen weblogs as appropriate medium to initiate and expand business. These webloggers or also known as direct profit-oriented webloggers (DPOWs) communicate and share knowledge with each other through social interaction. However, survivability is the main issue among DPOW. Frequent communication with influential webloggers is one of the way to keep survive as DPOW. This paper aims to understand the network structure and identify influential webloggers within the network. Proper understanding of the network structure can assist us in knowing how the information is exchanged among members and enhance survivability among DPOW. 30 DPOW were involved in this study. Degree centrality and betweenness centrality measurement in Social Network Analysis (SNA) were used to examine the strength relation and identify influential webloggers within the network. Thus, webloggers with the highest value of these measurements are considered as the most influential webloggers in the network.

  6. SLUDGE TREATMENT PROJECT ENGINEERED CONTAINER RETRIEVAL AND TRANSFER SYSTEM PRELIMINARY DESIGN HAZARD ANALYSIS SUPPLEMENT 1

    Energy Technology Data Exchange (ETDEWEB)

    FRANZ GR; MEICHLE RH

    2011-07-18

    This 'What/If' Hazards Analysis addresses hazards affecting the Sludge Treatment Project Engineered Container Retrieval and Transfer System (ECRTS) NPH and external events at the preliminary design stage. In addition, the hazards of the operation sequence steps for the mechanical handling operations in preparation of Sludge Transport and Storage Container (STSC), disconnect STSC and prepare STSC and Sludge Transport System (STS) for shipping are addressed.

  7. Preliminary Failure Modes and Effects Analysis of the US Massive Gas Injection Disruption Mitigation System Design

    Energy Technology Data Exchange (ETDEWEB)

    Lee C. Cadwallader

    2013-10-01

    This report presents the results of a preliminary failure modes and effects analysis (FMEA) of a candidate design for the ITER Disruption Mitigation System. This candidate is the Massive Gas Injection System that provides machine protection in a plasma disruption event. The FMEA was quantified with “generic” component failure rate data as well as some data calculated from operating facilities, and the failure events were ranked for their criticality to system operation.

  8. Preliminary Failure Modes and Effects Analysis of the US DCLL Test Blanket Module

    Energy Technology Data Exchange (ETDEWEB)

    Lee C. Cadwallader

    2007-08-01

    This report presents the results of a preliminary failure modes and effects analysis (FMEA) of a small tritium-breeding test blanket module design for the International Thermonuclear Experimental Reactor. The FMEA was quantified with “generic” component failure rate data, and the failure events are binned into postulated initiating event families and frequency categories for safety assessment. An appendix to this report contains repair time data to support an occupational radiation exposure assessment for test blanket module maintenance.

  9. Preliminary Failure Modes and Effects Analysis of the US DCLL Test Blanket Module

    Energy Technology Data Exchange (ETDEWEB)

    Lee C. Cadwallader

    2010-06-01

    This report presents the results of a preliminary failure modes and effects analysis (FMEA) of a small tritium-breeding test blanket module design for the International Thermonuclear Experimental Reactor. The FMEA was quantified with “generic” component failure rate data, and the failure events are binned into postulated initiating event families and frequency categories for safety assessment. An appendix to this report contains repair time data to support an occupational radiation exposure assessment for test blanket module maintenance.

  10. Students' Interest in Social Studies and Negotiation Self-Efficacy: A Meta-Analysis of the GlobalEd Project

    Science.gov (United States)

    Yukhymenko, Mariya

    2011-01-01

    The current meta-analysis study summarizes the effects of the GlobalEd Project, a web-based educational intervention of international negotiations embedded within social studies curricula, on middle and high school students' interest in social studies and negotiation self efficacy. Meta-analytic evidence supports statistically significant…

  11. PRELIMINARY PHYTOCHEMICAL ANALYSIS AND ACUTE ORAL TOXICITY STUDY OF CLITORIA TERNATEA LINN. ROOTS IN ALBINO MICE

    Directory of Open Access Journals (Sweden)

    Deka Manalisha

    2011-12-01

    Full Text Available Clitoria ternatea has been using since the ancient times for its medicinal values. Almost all the parts of the plant have medicinal property. The root of the plant is reported to have anti diarrheal, Anti histamic, cholinergic activity etc. Traditionally the root has been using for the treatment of many diseases like leucorrhoea, diarrhea, urinary problems, diuretic, impotency, stomach trouble etc. The present study was designed to investigate the preliminary phytochemical analysis and acute oral toxicity of the root of the plant. The shed dried materials were grinded and used in the study. The preliminary phytochemical analysis was done by following standard protocols. For acute oral toxicity study, methanolic extract of the root was used. The extract was prepared by standard protocol. The preliminary phytochemical analysis showed the presence of proteins, carbohydrates, glycosides, resins, saponin, flavonoid, alkaloids, steroids and phenol. The acute oral toxicity study showed no mortality up to a dose of 3000 mg per kg body weight. The presence of plant chemicals revealed the medicinal values and the non toxic property of the plant indicated the value of the plant as medicine. Thus we can conclude that, the root of the plant can be used as a safe drug against many diseases.

  12. PRELIMINARY PHYTOCHEMICAL ANALYSIS AND ACUTE ORAL TOXICITY STUDY OF MUCUNA PRURIENS LINN. IN ALBINO MICE

    Directory of Open Access Journals (Sweden)

    Deka Manalisha

    2012-02-01

    Full Text Available Mucuna Pruriens Linn. is an annual, climbing shrub which has an important place among aphrodisiac herbs in India since the ancient times. The plant has been using traditionally for many medicinal purposes such as Infertility, Parkinson’s disease, Loss of libido, Antioxidant, Anti venom, Anti microbial etc. The present study was carried out to investigate the preliminary phytochemical analysis and acute oral toxicity of the seeds of M.pruriens on albino mice. Matured seeds of M.pruriens were dried in shed and grinded in a mechanical grinder. The preliminary phytochemical analysis was done by following standard protocols. For acute oral toxicity study, methanolic extract of the seeds were used. The extract was prepared in a Soxlet apparatus. The preliminary phytochemical analysis showed the presence of protein, carbohydrates, glycosides, alkaloids, steroids, flavonoids, phenols and tannins. The acute oral toxicity study showed no mortality up to a dose of 4000 mg per kg body weight. The presence of plant chemicals revealed the medicinal values and the non toxic property of the plant indicated the value of the plant as medicine. Thus, we can conclude that, the seed of the plant can be used as a safe drug against many diseases.

  13. Drivers of wetland conversion: a global meta-analysis.

    Directory of Open Access Journals (Sweden)

    Sanneke van Asselen

    Full Text Available Meta-analysis of case studies has become an important tool for synthesizing case study findings in land change. Meta-analyses of deforestation, urbanization, desertification and change in shifting cultivation systems have been published. This present study adds to this literature, with an analysis of the proximate causes and underlying forces of wetland conversion at a global scale using two complementary approaches of systematic review. Firstly, a meta-analysis of 105 case-study papers describing wetland conversion was performed, showing that different combinations of multiple-factor proximate causes, and underlying forces, drive wetland conversion. Agricultural development has been the main proximate cause of wetland conversion, and economic growth and population density are the most frequently identified underlying forces. Secondly, to add a more quantitative component to the study, a logistic meta-regression analysis was performed to estimate the likelihood of wetland conversion worldwide, using globally-consistent biophysical and socioeconomic location factor maps. Significant factors explaining wetland conversion, in order of importance, are market influence, total wetland area (lower conversion probability, mean annual temperature and cropland or built-up area. The regression analyses results support the outcomes of the meta-analysis of the processes of conversion mentioned in the individual case studies. In other meta-analyses of land change, similar factors (e.g., agricultural development, population growth, market/economic factors are also identified as important causes of various types of land change (e.g., deforestation, desertification. Meta-analysis helps to identify commonalities across the various local case studies and identify which variables may lead to individual cases to behave differently. The meta-regression provides maps indicating the likelihood of wetland conversion worldwide based on the location factors that have

  14. Improved generalized cell mapping for global analysis of dynamical systems

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Three main parts of generalized cell mapping are improved for global analysis. A simple method, which is not based on the theory of digraphs, is presented to locate complete self-cycling sets that corre- spond to attractors and unstable invariant sets involving saddle, unstable periodic orbit and chaotic saddle. Refinement for complete self-cycling sets is developed to locate attractors and unstable in- variant sets with high degree of accuracy, which can start with a coarse cell structure. A nonuniformly interior-and-boundary sampling technique is used to make the refinement robust. For homeomorphic dissipative dynamical systems, a controlled boundary sampling technique is presented to make gen- eralized cell mapping method with refinement extremely accurate to obtain invariant sets. Recursive laws of group absorption probability and expected absorption time are introduced into generalized cell mapping, and then an optimal order for quantitative analysis of transient cells is established, which leads to the minimal computational work. The improved method is applied to four examples to show its effectiveness in global analysis of dynamical systems.

  15. Improved generalized cell mapping for global analysis of dynamical systems

    Institute of Scientific and Technical Information of China (English)

    ZOU HaiLin; XU JianXue

    2009-01-01

    Three main parts of generalized cell mapping are improved for global analysis. A simple method, whichis not based on the theory of digraphs, is presented to locate complete self-cycling sets that corre-spond to attractors and unstable invariant sets involving saddle, unstable periodic orbit and chaotic saddle. Refinement for complete self-cycling sets is developed to locate attractors and unstable in-variant sets with high degree of accuracy, which can start with a coarse cell structure. A nonuniformly interior-and-boundary sampling technique is used to make the refinement robust. For homeomorphic dissipative dynamical systems, a controlled boundary sampling technique is presented to make gen-eralized cell mapping method with refinement extremely accurate to obtain invariant sets. Recursive laws of group absorption probability and expected absorption time are introduced into generalized cell mapping, and then an optimal order for quantitative analysis of transient cells is established, which leads to the minimal computational work. The improved method is applied to four examples to show its effectiveness in global analysis of dynamical systems.

  16. A proteomic strategy for global analysis of plant protein complexes.

    Science.gov (United States)

    Aryal, Uma K; Xiong, Yi; McBride, Zachary; Kihara, Daisuke; Xie, Jun; Hall, Mark C; Szymanski, Daniel B

    2014-10-01

    Global analyses of protein complex assembly, composition, and location are needed to fully understand how cells coordinate diverse metabolic, mechanical, and developmental activities. The most common methods for proteome-wide analysis of protein complexes rely on affinity purification-mass spectrometry or yeast two-hybrid approaches. These methods are time consuming and are not suitable for many plant species that are refractory to transformation or genome-wide cloning of open reading frames. Here, we describe the proof of concept for a method allowing simultaneous global analysis of endogenous protein complexes that begins with intact leaves and combines chromatographic separation of extracts from subcellular fractions with quantitative label-free protein abundance profiling by liquid chromatography-coupled mass spectrometry. Applying this approach to the crude cytosolic fraction of Arabidopsis thaliana leaves using size exclusion chromatography, we identified hundreds of cytosolic proteins that appeared to exist as components of stable protein complexes. The reliability of the method was validated by protein immunoblot analysis and comparisons with published size exclusion chromatography data and the masses of known complexes. The method can be implemented with appropriate instrumentation, is applicable to any biological system, and has the potential to be further developed to characterize the composition of protein complexes and measure the dynamics of protein complex localization and assembly under different conditions.

  17. Indian plant germplasm on the global platter: an analysis.

    Directory of Open Access Journals (Sweden)

    Sherry R Jacob

    importantly, about 50% of the Indian-origin accessions deposited in SGSV are traditional varieties or landraces with defined traits which form the backbone of any crop gene pool. This paper is also attempting to correlate the global data on Indian-origin germplasm with the national germplasm export profile. The analysis from this paper is discussed with the perspective of possible implications in the access and benefit sharing regime of both the International Treaty on Plant Genetic Resources for Food and Agriculture and the newly enforced Nagoya Protocol under the Convention on Biological Diversity.

  18. Indian plant germplasm on the global platter: an analysis.

    Science.gov (United States)

    Jacob, Sherry R; Tyagi, Vandana; Agrawal, Anuradha; Chakrabarty, Shyamal K; Tyagi, Rishi K

    2015-01-01

    , about 50% of the Indian-origin accessions deposited in SGSV are traditional varieties or landraces with defined traits which form the backbone of any crop gene pool. This paper is also attempting to correlate the global data on Indian-origin germplasm with the national germplasm export profile. The analysis from this paper is discussed with the perspective of possible implications in the access and benefit sharing regime of both the International Treaty on Plant Genetic Resources for Food and Agriculture and the newly enforced Nagoya Protocol under the Convention on Biological Diversity.

  19. Generating an Arabic Calligraphy Text Blocks for Global Texture Analysis

    Directory of Open Access Journals (Sweden)

    Bilal Bataineh

    2011-01-01

    Full Text Available This paper objective is to improve the current method for generating an Arabic Calligraphy text blocks. We test on seven types of Arabic Calligraphy text. We apply  projection profiles and a proposed filter to discriminate each line of the Arabic Calligraphy scripts. After performing text detection, skew correction, text and line normalization subsequently, we generate Arabic Calligraphy text blocks for global texture analysis purposes. We compare our proposed filter with current method and median filter. The results show that the proposed filter  is outperformed. The proposed method can be further  improved to boost the overall performance.

  20. Preliminary CFD Analysis for HVAC System Design of a Containment Building

    Energy Technology Data Exchange (ETDEWEB)

    Son, Sung Man; Choi, Choengryul [ELSOLTEC, Yongin (Korea, Republic of); Choo, Jae Ho; Hong, Moonpyo; Kim, Hyungseok [KEPCO Engineering and Construction, Gimcheon (Korea, Republic of)

    2016-10-15

    HVAC (Heating, Ventilation, Air Conditioning) system has been mainly designed based on overall heat balance and averaging concepts, which is simple and useful for designing overall system. However, such a method has the disadvantage that cannot predict the local flow and temperature distributions in a containment building. In this study, a CFD (Computational Fluid Dynamics) preliminary analysis is carried out to obtain detailed flow and temperature distributions in a containment building and to ensure that such information can be obtained via CFD analysis. This approach can be useful for hydrogen analysis in an accident related to hydrogen released into a containment building. In this study, CFD preliminary analysis has been performed to obtain the detailed information of the reactor containment building by using the CFD analysis techniques and to ensure that such information can be obtained via CFD analysis. We confirmed that CFD analysis can offer enough detailed information about flow patterns and temperature field and that CFD technique is a useful tool for HVAC design of nuclear power plants.

  1. A meta-analysis of global urban land expansion.

    Directory of Open Access Journals (Sweden)

    Karen C Seto

    Full Text Available The conversion of Earth's land surface to urban uses is one of the most irreversible human impacts on the global biosphere. It drives the loss of farmland, affects local climate, fragments habitats, and threatens biodiversity. Here we present a meta-analysis of 326 studies that have used remotely sensed images to map urban land conversion. We report a worldwide observed increase in urban land area of 58,000 km(2 from 1970 to 2000. India, China, and Africa have experienced the highest rates of urban land expansion, and the largest change in total urban extent has occurred in North America. Across all regions and for all three decades, urban land expansion rates are higher than or equal to urban population growth rates, suggesting that urban growth is becoming more expansive than compact. Annual growth in GDP per capita drives approximately half of the observed urban land expansion in China but only moderately affects urban expansion in India and Africa, where urban land expansion is driven more by urban population growth. In high income countries, rates of urban land expansion are slower and increasingly related to GDP growth. However, in North America, population growth contributes more to urban expansion than it does in Europe. Much of the observed variation in urban expansion was not captured by either population, GDP, or other variables in the model. This suggests that contemporary urban expansion is related to a variety of factors difficult to observe comprehensively at the global level, including international capital flows, the informal economy, land use policy, and generalized transport costs. Using the results from the global model, we develop forecasts for new urban land cover using SRES Scenarios. Our results show that by 2030, global urban land cover will increase between 430,000 km(2 and 12,568,000 km(2, with an estimate of 1,527,000 km(2 more likely.

  2. A meta-analysis of global urban land expansion.

    Science.gov (United States)

    Seto, Karen C; Fragkias, Michail; Güneralp, Burak; Reilly, Michael K

    2011-01-01

    The conversion of Earth's land surface to urban uses is one of the most irreversible human impacts on the global biosphere. It drives the loss of farmland, affects local climate, fragments habitats, and threatens biodiversity. Here we present a meta-analysis of 326 studies that have used remotely sensed images to map urban land conversion. We report a worldwide observed increase in urban land area of 58,000 km(2) from 1970 to 2000. India, China, and Africa have experienced the highest rates of urban land expansion, and the largest change in total urban extent has occurred in North America. Across all regions and for all three decades, urban land expansion rates are higher than or equal to urban population growth rates, suggesting that urban growth is becoming more expansive than compact. Annual growth in GDP per capita drives approximately half of the observed urban land expansion in China but only moderately affects urban expansion in India and Africa, where urban land expansion is driven more by urban population growth. In high income countries, rates of urban land expansion are slower and increasingly related to GDP growth. However, in North America, population growth contributes more to urban expansion than it does in Europe. Much of the observed variation in urban expansion was not captured by either population, GDP, or other variables in the model. This suggests that contemporary urban expansion is related to a variety of factors difficult to observe comprehensively at the global level, including international capital flows, the informal economy, land use policy, and generalized transport costs. Using the results from the global model, we develop forecasts for new urban land cover using SRES Scenarios. Our results show that by 2030, global urban land cover will increase between 430,000 km(2) and 12,568,000 km(2), with an estimate of 1,527,000 km(2) more likely.

  3. GC-MS analysis, preliminary phytochemical screening, physicochemical analysis and anti-diabetic activity of ethanol extract of Jasminum cuspidatum leaves

    National Research Council Canada - National Science Library

    Singumsetty Vinay; Shaik Karimulla; Devarajan Saravanan

    2014-01-01

    The purpose of the present study was investigating the GC-MS analysis, preliminary phytochemical screening, physicochemical analysis and anti-diabetic activity of ethanol extract of the leaves of Jasminum cuspidatum...

  4. ANSI/ASHRAE/IESNA Standard 90.1-2010 Preliminary Determination Quantitative Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Halverson, Mark A.; Liu, Bing; Rosenberg, Michael I.

    2010-11-01

    The United States (U.S.) Department of Energy (DOE) conducted a preliminary quantitative analysis to assess whether buildings constructed according to the requirements of the American National Standards Institute (ANSI)/American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE)/Illuminating Engineering Society of North America (IESNA) Standard 90.1-2010 (ASHRAE Standard 90.1-2010, Standard 90.1-2010, or 2010 edition) would result in energy savings compared with buildings constructed to ANSI/ASHRAE/IESNA Standard 90.1-2007(ASHRAE Standard 90.1-2007, Standard 90.1-2007, or 2007 edition). The preliminary analysis considered each of the 109 addenda to ASHRAE Standard 90.1-2007 that were included in ASHRAE Standard 90.1-2010. All 109 addenda processed by ASHRAE in the creation of Standard 90.1-2010 from Standard 90.1-2007 were reviewed by DOE, and their combined impact on a suite of 16 building prototype models in 15 ASHRAE climate zones was considered. Most addenda were deemed to have little quantifiable impact on building efficiency for the purpose of DOE’s preliminary determination. However, out of the 109 addenda, 34 were preliminarily determined to have measureable and quantifiable impact.

  5. A Global Sensitivity Analysis Methodology for Multi-physics Applications

    Energy Technology Data Exchange (ETDEWEB)

    Tong, C H; Graziani, F R

    2007-02-02

    Experiments are conducted to draw inferences about an entire ensemble based on a selected number of observations. This applies to both physical experiments as well as computer experiments, the latter of which are performed by running the simulation models at different input configurations and analyzing the output responses. Computer experiments are instrumental in enabling model analyses such as uncertainty quantification and sensitivity analysis. This report focuses on a global sensitivity analysis methodology that relies on a divide-and-conquer strategy and uses intelligent computer experiments. The objective is to assess qualitatively and/or quantitatively how the variabilities of simulation output responses can be accounted for by input variabilities. We address global sensitivity analysis in three aspects: methodology, sampling/analysis strategies, and an implementation framework. The methodology consists of three major steps: (1) construct credible input ranges; (2) perform a parameter screening study; and (3) perform a quantitative sensitivity analysis on a reduced set of parameters. Once identified, research effort should be directed to the most sensitive parameters to reduce their uncertainty bounds. This process is repeated with tightened uncertainty bounds for the sensitive parameters until the output uncertainties become acceptable. To accommodate the needs of multi-physics application, this methodology should be recursively applied to individual physics modules. The methodology is also distinguished by an efficient technique for computing parameter interactions. Details for each step will be given using simple examples. Numerical results on large scale multi-physics applications will be available in another report. Computational techniques targeted for this methodology have been implemented in a software package called PSUADE.

  6. Preliminary phytochemical analysis and DPPH free radical scavenging activity of Trewia nudiflora Linn. roots and leaves.

    Science.gov (United States)

    Balakrishnan, N; Srivastava, Mayank; Tiwari, Pallavi

    2013-11-01

    Oxidative stress is one of the major causative factors of many chronic and degenerative diseases. Plants have been used in traditional medicine in different parts of world for thousands of years and continue to provide new remedies for human kind. The present study was to investigate the preliminary phytochemical analysis of various extracts of roots and leaves of Trewia nudiflora (Euphorbiaceae) and antioxidant activity by 1,1,diphenyl-2-picryl hydrazyl (DPPH) radical scavenging method. The preliminary phytochemical screening showed the presence of several phytochemicals including alkaloids, glycosides, flavonoids, steroids, phenolic compounds and tannins. The ethanol and aqueous extracts of roots and leaves of Trewia nudiflora showed significant antioxidant activity compared to standard drug ascorbic acid.

  7. CONSTRUCTION OF THE CHINESE LEARNERS' PARALLEL CORPUS OF JAPANESE AND ITS PRELIMINARY ANALYSIS

    Directory of Open Access Journals (Sweden)

    Masatake Dantsuji

    2004-01-01

    Full Text Available This study aims to introduce the project to construct the Chinese learners' corpus (LC of Japanese at Dalian University of Technology (DUT, and detail the LC construction, development of DUT Corpus Linguistics Tools, and contribution to the education of Japanese as a second language. The outstanding characteristic of the LC is its parallel form with learners' Japanese texts and their Chinese translation, which enables us to make comprehensive analysis of the influence of Chinese (L1 to Japanese (L2. We have made a preliminary analysis of the errors contained.

  8. Preliminary Design and Analysis of the ARES Atmospheric Flight Vehicle Thermal Control System

    Science.gov (United States)

    Gasbarre, J. F.; Dillman, R. A.

    2003-01-01

    The Aerial Regional-scale Environmental Survey (ARES) is a proposed 2007 Mars Scout Mission that will be the first mission to deploy an atmospheric flight vehicle (AFV) on another planet. This paper will describe the preliminary design and analysis of the AFV thermal control system for its flight through the Martian atmosphere and also present other analyses broadening the scope of that design to include other phases of the ARES mission. Initial analyses are discussed and results of trade studies are presented which detail the design process for AFV thermal control. Finally, results of the most recent AFV thermal analysis are shown and the plans for future work are discussed.

  9. Global pattern analysis and classification of dermoscopic images using textons

    Science.gov (United States)

    Sadeghi, Maryam; Lee, Tim K.; McLean, David; Lui, Harvey; Atkins, M. Stella

    2012-02-01

    Detecting and classifying global dermoscopic patterns are crucial steps for detecting melanocytic lesions from non-melanocytic ones. An important stage of melanoma diagnosis uses pattern analysis methods such as 7-point check list, Menzies method etc. In this paper, we present a novel approach to investigate texture analysis and classification of 5 classes of global lesion patterns (reticular, globular, cobblestone, homogeneous, and parallel pattern) in dermoscopic images. Our statistical approach models the texture by the joint probability distribution of filter responses using a comprehensive set of the state of the art filter banks. This distribution is represented by the frequency histogram of filter response cluster centers called textons. We have also examined other two methods: Joint Distribution of Intensities (JDI) and Convolutional Restricted Boltzmann Machine (CRBM) to learn the pattern specific features to be used for textons. The classification performance is compared over the Leung and Malik filters (LM), Root Filter Set (RFS), Maximum Response Filters (MR8), Schmid, Laws and our proposed filter set as well as CRBM and JDI. We analyzed 375 images of the 5 classes of the patterns. Our experiments show that the joint distribution of color (JDC) in the L*a*b* color space outperforms the other color spaces with a correct classification rate of 86.8%.

  10. Global point signature for shape analysis of carpal bones

    Science.gov (United States)

    Chaudhari, Abhijit J.; Leahy, Richard M.; Wise, Barton L.; Lane, Nancy E.; Badawi, Ramsey D.; Joshi, Anand A.

    2014-02-01

    We present a method based on spectral theory for the shape analysis of carpal bones of the human wrist. We represent the cortical surface of the carpal bone in a coordinate system based on the eigensystem of the two-dimensional Helmholtz equation. We employ a metric—global point signature (GPS)—that exploits the scale and isometric invariance of eigenfunctions to quantify overall bone shape. We use a fast finite-element-method to compute the GPS metric. We capitalize upon the properties of GPS representation—such as stability, a standard Euclidean (ℓ2) metric definition, and invariance to scaling, translation and rotation—to perform shape analysis of the carpal bones of ten women and ten men from a publicly-available database. We demonstrate the utility of the proposed GPS representation to provide a means for comparing shapes of the carpal bones across populations.

  11. Risk-analysis of global climate tipping points

    Energy Technology Data Exchange (ETDEWEB)

    Frieler, Katja; Meinshausen, Malte; Braun, N. [Potsdam Institute for Climate Impact Research e.V., Potsdam (Germany). PRIMAP Research Group] [and others

    2012-09-15

    vulnerable to climate change impacts. Here we focus on tipping elements within the physical / biological system. In the following two sections, we briefly highlight some of our methodological research regarding global mean precipitation and regional climate change. These methodological developments provided the underpinning for our subsequent analysis of individual large-scale climate impacts, as e.g. mass losses of the Greenland ice sheet, the release of greenhouse gases by the thawing of permafrost regions or the threat of coral reefs by high ocean temperatures.

  12. Multidisciplinary High-Fidelity Analysis and Optimization of Aerospace Vehicles. Part 2; Preliminary Results

    Science.gov (United States)

    Walsh, J. L.; Weston, R. P.; Samareh, J. A.; Mason, B. H.; Green, L. L.; Biedron, R. T.

    2000-01-01

    An objective of the High Performance Computing and Communication Program at the NASA Langley Research Center is to demonstrate multidisciplinary shape and sizing optimization of a complete aerospace vehicle configuration by using high-fidelity finite-element structural analysis and computational fluid dynamics aerodynamic analysis in a distributed, heterogeneous computing environment that includes high performance parallel computing. A software system has been designed and implemented to integrate a set of existing discipline analysis codes, some of them computationally intensive, into a distributed computational environment for the design of a high-speed civil transport configuration. The paper describes both the preliminary results from implementing and validating the multidisciplinary analysis and the results from an aerodynamic optimization. The discipline codes are integrated by using the Java programming language and a Common Object Request Broker Architecture compliant software product. A companion paper describes the formulation of the multidisciplinary analysis and optimization system.

  13. Waste Feed Delivery System Phase 1 Preliminary RAM Analysis [SEC 1 and 2

    Energy Technology Data Exchange (ETDEWEB)

    DYKES, A.A.

    2000-10-11

    This report presents the updated results of the preliminary reliability, availability, and maintainability (RAM) analysis of selected waste feed delivery (WFD) operations to be performed by the Tank Farm Contractor (TFC) during Phase I activities in support of the Waste Treatment and Immobilization Plant (WTP). For planning purposes, waste feed tanks are being divided into five classes in accordance with the type of waste in each tank and the activities required to retrieve, qualify, and transfer waste feed. This report reflects the baseline design and operating concept, as of the beginning of Fiscal Year 2000, for the delivery of feed from three of these classes, represented by source tanks 241-AN-102, 241-AZ-101 and 241-AN-105. The preliminary RAM analysis quantifies the potential schedule delay associated with operations and maintenance (OBM) field activities needed to accomplish these operations. The RAM analysis is preliminary because the system design, process definition, and activity planning are in a state of evolution. The results are being used to support the continuing development of an O&M Concept tailored to the unique requirements of the WFD Program, which is being documented in various volumes of the Waste Feed Delivery Technical Basis (Carlson. 1999, Rasmussen 1999, and Orme 2000). The waste feed provided to the WTP must: (1) meet limits for chemical and radioactive constituents based on pre-established compositional envelopes (i.e., feed quality); (2) be in acceptable quantities within a prescribed sequence to meet feed quantities; and (3) meet schedule requirements (i.e., feed timing). In the absence of new criteria related to acceptable schedule performance due to the termination of the TWRS Privatization Contract, the original criteria from the Tank Waste Remediation System (77443s) Privatization Contract (DOE 1998) will continue to be used for this analysis.

  14. Global stability analysis of turbulent 3D wakes

    Science.gov (United States)

    Rigas, Georgios; Sipp, Denis; Juniper, Matthew

    2015-11-01

    At low Reynolds numbers, corresponding to laminar and transitional regimes, hydrodynamic stability theory has aided the understanding of the dynamics of bluff body wake-flows and the application of effective control strategies. However, flows of fundamental importance to many industries, in particular the transport industry, involve high Reynolds numbers and turbulent wakes. Despite their turbulence, such wake flows exhibit organisation which is manifested as coherent structures. Recent work has shown that the turbulent coherent structures retain the shape of the symmetry-breaking laminar instabilities and only those manifest as large-scale structures in the near wake (Rigas et al., JFM vol. 750:R5 2014, JFM vol. 778:R2 2015). Based on the findings of the persistence of the laminar instabilities at high Reynolds numbers, we investigate the global stability characteristics of a turbulent wake generated behind a bluff three-dimensional axisymmetric body. We perform a linear global stability analysis on the experimentally obtained mean flow and we recover the dynamic characteristics and spatial structure of the coherent structures, which are linked to the transitional instabilities. A detailed comparison of the predictions with the experimental measurements will be provided.

  15. Global Analysis of Solar Neutrino Oscillations Including SNO CC Measurement

    CERN Document Server

    Bahcall, J N; Peña-Garay, C; Bahcall, John N; Peña-Garay, Carlos

    2001-01-01

    For active and sterile neutrinos, we present the globally allowed solutions for two neutrino oscillations. We include the SNO CC measurement and all other relevant solar neutrino and reactor data. Five active neutrino oscillation solutions (LMA, LOW, SMA, VAC, and Just So2) are currently allowed at 3 sigma; three sterile neutrino solutions (Just So2, SMA, and VAC) are allowed at 3 sigma. The goodness of fit is satisfactory for all eight solutions. We also investigate the robustness of the allowed solutions by carrying out global analyses with and without: 1) imposing solar model constraints on the 8B neutrino flux, 2) including the Super-Kamiokande spectral energy distribution and day-night data, 3) using an enhanced CC cross section for deuterium (due to radiative corrections), and 4) a optimistic, hypothetical reduction by a factor of three of the error of the SNO CC rate. For every analysis strategy used in this paper, the most favored solutions all involve large mixing angles: LMA, LOW, or VAC. The favore...

  16. Revisiting global body politics in Nepal: A reflexive analysis.

    Science.gov (United States)

    Harcourt, Wendy

    2016-01-01

    Using the example of a human rights training in Nepal, the author looks at global body politics in a reflexive piece on her engagement in development practices that translate western feminist ideas on gender inequality and empowerment via UN human rights policies into non-western contexts. It firsts look at postcolonial and critical literature on feminist engagement in gender and development processes including a discussion on the concept of global body politics before examining briefly the framing of gender-based violence in Nepal. The core of the paper is a reflexive analysis and interrogation of the training in Nepal in order to bring out the tensions and contradictions around western developmental, feminist and human rights discourses. The discussion looks at how difficult it is for feminist, human rights and developmental discourses and practices to unmoor themselves from the notion of the 'expert' and those who do the rights/work/righting rights training and those who are perennially seen as requiring training. The conclusion reflects on possibilities of other epistemic practices found in intercultural dialogues.

  17. Global Analysis of Several Bands of the CF_4 Molecule

    Science.gov (United States)

    Carlos, Mickaël; Gruson, Océane; Boudon, Vincent; Georges, Robert; Pirali, Olivier; Asselin, Pierre

    2016-06-01

    Carbon tetrafluoride is a powerful greenhouse gas, mainly of anthropogenic origin. Its absorption spectrum is, however, still badly modeled, especially for hot bands in the strongly absorbing ν_3 region. To overcome this problem, we have undertaken a systematic study of all the lower rovibrational transitions of this molecule. In particular, new far-infrared spectra recorded at the SOLEIL Synchrotron facility give access to bands implying the ``forbidden'' modes ν_1 and ν_2 which have only been investigated previously thanks to stimulated Raman spectroscopy, that is with a lower accuracy and much less data. Combined with the previous analyses performed in our group, we thus report here a new global fit of line positions of CF_4 by considering several transitions altogether: ν_2, 2ν_2-ν_2, ν_4, 2ν_4, ν_3 and ν_3-2ν_2. This gives a consistent set of molecular parameters that will be of great help for the analysis of hot bands like ν_3+ν_2-ν_2. A second separate global fit including the ν_1, ν_1-ν_4 and 2ν_1-ν_1 bands will also be presented. V. Boudon, D. Bermejo, R. Z. Martinez, J. Raman Spectrosc. 44, 731?738 (2013). V. Boudon, J. Mitchell, A. Domanskaya, C. Maul, R; Georges, A. Benidar, W. G. Harter, Mol. Phys. 109, 17--18 (2011)

  18. GLobal Ocean Data Analysis Project (GLODAP) version 1.1 (NODC Accession 0001644)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The GLobal Ocean Data Analysis Project (GLODAP) is a cooperative effort to coordinate global synthesis projects funded through NOAA/DOE and NSF as part of the Joint...

  19. A Comparative Study: Globality versus Locality for Graph Construction in Discriminant Analysis

    Directory of Open Access Journals (Sweden)

    Bo Yang

    2014-01-01

    Discriminant Analysis (GmGcDA just based on globality alone, GmLcDA, and LmGcDA, we suggest that the joint of locally constructed intraclass and globally constructed interclass graphs is more discriminant.

  20. World-Systems Analysis, Globalization, and Incorporated Comparison

    Directory of Open Access Journals (Sweden)

    Phillip McMichael

    2015-08-01

    Full Text Available When Immanuel Wallerstein (1974 subverted the mid-1970s social science scene with his concept of the ‘world-system,’ development, the ‘master’ concept of social theory, suffered a fatal blow. Wallerstein’s critique of development emphasized its misapplication as a national strategy in a hierarchical world where only some states can ‘succeed.’ Wallerstein’s path-breaking epistemological challenge to the modernization paradigm reformulated the unit of analysis of development from the nation-state to the ‘world-system.’ To be sure, the past three decades have seen reformulations, coined to address the failures of the development enterprise: frombasic needs, through participation in the world market, globalization, to local sustainability. But development, the organizing myth of our age, has never recovered.

  1. Entropy-complexity analysis in some globally-coupled systems

    Science.gov (United States)

    Chrisment, Antoine M.; Firpo, Marie-Christine

    2016-10-01

    Globally-coupled N-body systems are well known to possess an intricate dynamics. When N is large, collective effects may drastically lower the effective dimension of the dynamics breaking the conditions on ergodicity necessary for the applicability of statistical mechanics. These problems are here illustrated and discussed through an entropy-complexity analysis of the repulsive Hamiltonian mean-field model. Using a Poincaré section of the mean-field time series provides a natural sampling time in the entropy-complexity treatment. This approach is shown to single-out the out-of-equilibrium dynamical features and to uncover a transition of the system dynamics from low-energy non-Boltzmann quasi-stationary states to high-energy stochastic-like behavior.

  2. Global in Time Analysis and Sensitivity Analysis for the Reduced NS- α Model of Incompressible Flow

    Science.gov (United States)

    Rebholz, Leo; Zerfas, Camille; Zhao, Kun

    2017-09-01

    We provide a detailed global in time analysis, and sensitivity analysis and testing, for the recently proposed (by the authors) reduced NS- α model. We extend the known analysis of the model to the global in time case by proving it is globally well-posed, and also prove some new results for its long time treatment of energy. We also derive PDE system that describes the sensitivity of the model with respect to the filtering radius parameter, and prove it is well-posed. An efficient numerical scheme for the sensitivity system is then proposed and analyzed, and proven to be stable and optimally accurate. Finally, two physically meaningful test problems are simulated: channel flow past a cylinder (including lift and drag calculations) and turbulent channel flow with {Re_{τ}=590}. The numerical results reveal that sensitivity is created near boundaries, and thus this is where the choice of the filtering radius is most critical.

  3. Stock assessment of Haliporoides triarthrus (Fam. Solenoceridae) off Mozambique: a preliminary analysis

    OpenAIRE

    Torstensen, E.; Pacule, H.

    1992-01-01

    The pink shrimp, Haliporoides triarthrus, is an important species in the deep-water shrimp fishery in Mozambique. Total catches are in the range of 1,500 to 2,700 tons, with the pink shrimp accounting for 70-90%. Estimates of growth parameters and of natural mortality are used for a preliminary assessment of the fishery, based on length-structured virtual population analysis and yield-per-recruit analyses. With an arbitrarily chosen terminal fishing mortality F, the results indicate a situati...

  4. Preliminary Analysis of Liquid Metal MHD Pressure Drop in the Blanket for the FDS

    Institute of Scientific and Technical Information of China (English)

    王红艳; 吴宜灿; 何晓雄

    2002-01-01

    Preliminary analysis and calculation of liquid metal Li17Pb83 magnetohydrodynamic (MHD) pressure drop in the blanket for the FDS have been presented to evaluate the significance of MHD effects on the thermal-hydraulic design of the blanket. To decrease the liquid metal MHD pressure drop, Al2O3 is applied as an electronically insulated coating onto the inner surface of the ducts. The requirement for the insulated coating to reduce the additional leakage pressure drop caused by coating imperfections has been analyzed. Finally, the total liquid metal MHD pressure drop and magnetic pump power in the FDS blanket have been given.

  5. Preliminary performance analysis of a transverse flow spectrally selective two-slab packed bed volumetric receiver

    CSIR Research Space (South Africa)

    Roos, TH

    2016-05-01

    Full Text Available stream_source_info Roos_2016_ABSTRACT.pdf.txt stream_content_type text/plain stream_size 2694 Content-Encoding UTF-8 stream_name Roos_2016_ABSTRACT.pdf.txt Content-Type text/plain; charset=UTF-8 21st SolarPACES... International Conference (SolarPACES 2015), 13-16 October 2015 Preliminary Performance Analysis of a Transverse Flow Spectrally Selective Two-slab Packed Bed Volumetric Receiver Thomas H. Roos1, a) and Thomas M. Harms2, b) 1Aeronautical Systems...

  6. Global Positioning System Analysis of a High School Football Scrimmage.

    Science.gov (United States)

    Gleason, Benjamin H; Sams, Matthew L; Salley, John T; Pustina, A Andrew; Stone, Michael H

    2017-08-01

    Gleason, BH, Sams, M, Salley, JT, Pustina, A, and Stone, MH. Global positioning system analysis of a high school football scrimmage. J Strength Cond Res 31(8): 2183-2188, 2017-The purpose of this study was to examine the physical demands of a high school American football scrimmage. Male high school football players (N = 25) participated in a spring scrimmage. Global positioning system data and game film were recorded throughout the entirety of the scrimmage to determine the total distance covered, the distance covered in different velocity bands, the number of accelerations and decelerations performed, and the work-to-rest ratio of the scrimmage. The athletes were divided into 2 groups: linemen (L) (N = 7) vs. nonlinemen (NL) (N = 8) for statistical analysis, and independent T-tests with Holm's sequential Bonferroni adjustment were used to determine differences in movement characteristics between the L and NL groups. Average play duration was 5.7 ± 2.1 seconds, whereas the rest interval was 33.4 ± 13.6 seconds between plays, for an overall exercise-to-rest ratio of 1:5.9. Total distance, standing and walking distance, running distance, striding distance, sprinting distance, and total high-speed running distance covered by NL was greater than L (statistically significant at p ≤ 0.05). Distances traveled in each velocity band by position and by play are also included to provide context of our findings. Data from the present study add to the pool of support for the use of position-specific training in preparing high school football players for competition.

  7. Preliminary Report: Analysis of the baseline study on the prevalence of Salmonella in laying hen flocks of Gallus gallus

    DEFF Research Database (Denmark)

    Hald, Tine

    This is a preliminary report on the analysis of the Community-wide baseline study to estimate the prevalence of Salmonella in laying hen flocks. It is being published pending the full analysis of the entire dataset from the baseline study. The report contains the elements necessary for the establ......This is a preliminary report on the analysis of the Community-wide baseline study to estimate the prevalence of Salmonella in laying hen flocks. It is being published pending the full analysis of the entire dataset from the baseline study. The report contains the elements necessary...

  8. Global/local methods research using a common structural analysis framework

    Science.gov (United States)

    Knight, Norman F., Jr.; Ransom, Jonathan B.; Griffin, O. H., Jr.; Thompson, Danniella M.

    1991-01-01

    Methodologies for global/local stress analysis are described including both two- and three-dimensional analysis methods. These methods are being developed within a common structural analysis framework. Representative structural analysis problems are presented to demonstrate the global/local methodologies being developed.

  9. The global burden of dengue: an analysis from the Global Burden of Disease Study 2013

    NARCIS (Netherlands)

    J.D. Stanaway (Jeffrey D.); D.S. Shepard (Donald); E.A. Undurraga (Eduardo); Halasa, Y.A. (Yara A); L.E. Coffeng (Luc); Brady, O.J. (Oliver J); Hay, S.I. (Simon I); Bedi, N. (Neeraj); I.M. Bensenor (Isabela M.); C.A. Castañeda-Orjuela (Carlos A); T.-W. Chuang (Ting-Wu); K.B. Gibney (Katherine B); Z.A. Memish (Ziad); A. Rafay (Anwar); K.N. Ukwaja (Kingsley N); N. Yonemoto (Naohiro); C.J.L. Murray (Christopher)

    2016-01-01

    textabstractBackground Dengue is the most common arbovirus infection globally, but its burden is poorly quantified. We estimated dengue mortality, incidence, and burden for the Global Burden of Disease Study 2013. Methods We modelled mortality from vital registration, verbal autopsy, and surveillanc

  10. The global burden of dengue: an analysis from the Global Burden of Disease Study 2013

    NARCIS (Netherlands)

    J.D. Stanaway (Jeffrey D.); D.S. Shepard (Donald); E.A. Undurraga (Eduardo); Halasa, Y.A. (Yara A); L.E. Coffeng (Luc); Brady, O.J. (Oliver J); Hay, S.I. (Simon I); Bedi, N. (Neeraj); I.M. Bensenor (Isabela M.); C.A. Castañeda-Orjuela (Carlos A); T.-W. Chuang (Ting-Wu); K.B. Gibney (Katherine B); Z.A. Memish (Ziad); A. Rafay (Anwar); K.N. Ukwaja (Kingsley N); N. Yonemoto (Naohiro); C.J.L. Murray (Christopher)

    2016-01-01

    textabstractBackground Dengue is the most common arbovirus infection globally, but its burden is poorly quantified. We estimated dengue mortality, incidence, and burden for the Global Burden of Disease Study 2013. Methods We modelled mortality from vital registration, verbal autopsy, and

  11. Globalization and Shanghai Model: A Retrospective and Prospective Analysis

    Directory of Open Access Journals (Sweden)

    Linsun Cheng

    2012-11-01

    Full Text Available Intended to shed light on the debate on the results of globalization and providebetter understanding of the influences of globalization upon China as well as theworld, this article traces the history of Shanghai’s economic globalization over thepast 170 years since 1843 and demonstrates the benefits and problems Shanghaireceived from (or connected to its economic globalization. Divided into threesections (Globalization, de-globalization and re-globalization of Shanghai’s economy;Manufacturing-Oriented vs. Tertiary-oriented—Shanghai’s Double PriorityStrategy of Economic Growth; Free market, state enterprises, and Shanghai’s mixedeconomy the article summarizes and analyzes several characteristics that madeShanghai a unique model in the history of globalization: In adapting and adoptinginevitable economic globalization, Shanghai created its unique model of economicdevelopment—widely embracing economic globalization; placing Shanghai’seconomy on a solid foundation of both strong modern manufacturing and strongtertiary industry (consisting of finance and insurance, real estate, transportations,post and telecommunication, wholesale and retailing; and creating a mixedeconomic structure with hybrid of private and state owned enterprises. TheShanghai model proves that globalization has been an unavoidable trend as scienceand technology have made the world “smaller” and “smaller.” Actively engaging intoeconomic globalization is the only way for Shanghai, as well as many developingcountries, to accelerate its economic growth.

  12. Preliminary phytochemical screening, Antibacterial potential and GC-MS analysis of two medicinal plant extracts.

    Science.gov (United States)

    Vijayaram, Seerangaraj; Kannan, Suruli; Saravanan, Konda Mani; Vasantharaj, Seerangaraj; Sathiyavimal, Selvam; P, Palanisamy Senthilkumar

    2016-05-01

    The presence study was aimed to catalyze the primary metabolites and their confirmation by using GC-MS analysis and antibacterial potential of leaf extract of two important medicinal plant viz., Eucalyptus and Azadirachta indica. The antibacterial potential of the methanol leaf extract of the studied species was tested against Escherichia coli, Pseudomonas aeruginosa, Klebsiellap neumoniae, Streptococcus pyogens, Staphylococcus aureus using by agar well diffusion method. The higher zone of inhibition (16mm) was observed against the bacterium Pseudomonas aeruginosa at 100μl concentration of methanol leaf extract. Preliminary phytochemical analysis of studied species shows that presence of phytochemical compounds like steroids, phenolic compounds and flavonoids. GC-MS analysis confirms the occurrence of 20 different compounds in the methanol leaf extract of the both studied species.

  13. 1972 preliminary safety analysis report based on a conceptual design of a proposed repository in Kansas

    Energy Technology Data Exchange (ETDEWEB)

    Blomeke, J.O.

    1977-08-01

    This preliminary safety analysis report is based on a proposed Federal Repository at Lyons, Kansas, for receiving, handling, and depositing radioactive solid wastes in bedded salt during the remainder of this century. The safety analysis applies to a hypothetical site in central Kansas identical to the Lyons site, except that it is free of nearby salt solution-mining operations and bore holes that cannot be plugged to Repository specifications. This PSAR contains much information that also appears in the conceptual design report. Much of the geological-hydrological information was gathered in the Lyons area. This report is organized in 16 sections: considerations leading to the proposed Repository, design requirements and criteria, a description of the Lyons site and its environs, land improvements, support facilities, utilities, different impacts of Repository operations, safety analysis, design confirmation program, operational management, requirements for eventually decommissioning the facility, design criteria for protection from severe natural events, and the proposed program of experimental investigations. (DLC)

  14. Preliminary Cluster Analysis For Several Representatives Of Genus Kerivoula (Chiroptera: Vespertilionidae) in Borneo

    Science.gov (United States)

    Hasan, Noor Haliza; Abdullah, M. T.

    2008-01-01

    The aim of the study is to use cluster analysis on morphometric parameters within the genus Kerivoula to produce a dendrogram and to determine the suitability of this method to describe the relationship among species within this genus. A total of 15 adult male individuals from genus Kerivoula taken from sampling trips around Borneo and specimens kept at the zoological museum of Universiti Malaysia Sarawak were examined. A total of 27 characters using dental, skull and external body measurements were recorded. Clustering analysis illustrated the grouping and morphometric relationships between the species of this genus. It has clearly separated each species from each other despite the overlapping of measurements of some species within the genus. Cluster analysis provides an alternative approach to make a preliminary identification of a species.

  15. Using modeling, satellite images and existing global datasets for rapid preliminary assessments of renewable energy resources: The case of Mali

    DEFF Research Database (Denmark)

    Nygaard, Ivan; Rasmussen, K.; Badger, Jake

    2010-01-01

    in the irrigated areas of the Niger inland delta that might be interesting from a renewable energy resource perspective. Finally, the paper discusses the role that renewable energy resources might play in the energy systems of Mali, given the spatio-temporal distribution of renewable energy resources. It is argued...... that at the current price of about 70 US$/barrel for fossil fuels, renewable energy resources are becoming economically as well as environmentally attractive options.......This paper presents a novel approach to the preliminary, low-cost, national-scale mapping of wind energy, solar energy and certain categories of bio-energy resources in developing countries, using Mali as an example. The methods applied make extensive use of satellite remote sensing...

  16. 卧龙区目标人群艾滋病知识宣传及行为干预效果评价%PRELIMINARY ANALYSIS ON THE EFFECTIVENESS OF HEALTH PROMOTION AND INTERVENTION OF GLOBAL FUND AIDS PROGRAM IN WOLONG DISTRICT

    Institute of Scientific and Technical Information of China (English)

    曾祥丽; 李萍; 冯义; 韦宛玉; 马伟科

    2011-01-01

    [Objective] To assess the fulfillment of Health promotion and intervention program by the round 3 of global fund in the Wolong District after 5 years implementation. [Methods] Investigation on HIV/AIDs related knowledge and condom use was conducted among middle school students, villagers, FSW, HIV infected persons and AIDS patients whom were surveyed with the same methods at the end of 2005, 2006, 2007 and 2008. [Results] From 2005 to 2008, the awareness percentage on AIDS of middle school students, residents, PLWHA and FSW increased significantly from 77.00% , 63.00% , 68.23%, 30.33% in 2005 to 90.14%, 85.00%, 83.33%, 80.59% in 2008 (f = 38.275, 61.837, 12.232, 179.054, P< 0.05) .Percentage of PLWHA who using condoms consistently with a HIV negative partner in last 3 months increased dramatically from 88.73% in 2005 to 100.00% in 2008.Percenuige of FSW who using condom in the last 12 months remained over 80%. [Conclusion] Although awareness rate of HIV/AIDS prevention among target population and condom use rate among PLWHA and FSW increase through campaign of health promotion and intervention in Wolong District, there are still over 15.00% target population who can't correctly identify ways of preventing the sexual transmission of HTV and condom use rate among PLWHA and FSW needs to be increased.Further health promotion and intervention campaign should be oriented to the needs of different target population in program counties.%[目的]分析第三轮中国全球基金艾滋病项目在卧龙区实施5年来的宣传干预效果.[方法]对卧龙区2005年、2006年、2007年、2008年底按照统一调查方案进行的中学生、村民、女性性服务者(FSW)、HIV感染者或AIDS病人(PLWHA)调查问卷进行分析.[结果]通过项目执行,卧龙区中学生、城乡居民、HIV感染者或AIDS病人(PLWHA)和女性性服务者(FSW)的艾滋病知识知晓率分别由2005年底的77.00%,63.00%,68.23%和30.33%上升到2008

  17. Multifractal detrended moving average analysis of global temperature records

    CERN Document Server

    Mali, Provash

    2015-01-01

    Long-range correlation and multifractal nature of the global monthly mean temperature anomaly time series over the period 1850-2012 are studied in terms of the multifractal detrended moving average (MFDMA) method. We try to address the source(s) of multifractality in the time series by comparing the results derived from the actual series with those from a set of shuffled and surrogate series. It is seen that the newly developed MFDMA method predicts a multifractal structure of the temperature anomaly time series that is more or less similar to that observed by other multifractal methods. In our analysis the major contribution of multifractality in the temperature records is found to be stemmed from long-range temporal correlation among the measurements, however the contribution of fat-tail distribution function of the records is not negligible. The results of the MFDMA analysis, which are found to depend upon the location of the detrending window, tend towards the observations of the multifractal detrended fl...

  18. Global analysis of small molecule binding to related protein targets.

    Directory of Open Access Journals (Sweden)

    Felix A Kruger

    2012-01-01

    Full Text Available We report on the integration of pharmacological data and homology information for a large scale analysis of small molecule binding to related targets. Differences in small molecule binding have been assessed for curated pairs of human to rat orthologs and also for recently diverged human paralogs. Our analysis shows that in general, small molecule binding is conserved for pairs of human to rat orthologs. Using statistical tests, we identified a small number of cases where small molecule binding is different between human and rat, some of which had previously been reported in the literature. Knowledge of species specific pharmacology can be advantageous for drug discovery, where rats are frequently used as a model system. For human paralogs, we demonstrate a global correlation between sequence identity and the binding of small molecules with equivalent affinity. Our findings provide an initial general model relating small molecule binding and sequence divergence, containing the foundations for a general model to anticipate and predict within-target-family selectivity.

  19. The purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Clostridium botulinum

    Energy Technology Data Exchange (ETDEWEB)

    Dobson, Renwick C. J., E-mail: rdobson@unimelb.edu.au; Atkinson, Sarah C. [Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010 (Australia); Bio21 Molecular Science and Biotechnology Institute, 30 Flemington Road, University of Melbourne, Parkville, Victoria 3010 (Australia); Gorman, Michael A. [St Vincents Institute, 9 Princes Street, Fitzroy, Victoria 3065 (Australia); Newman, Janet M. [CSIRO Division of Molecular and Health Technologies, 343 Royal Parade, Parkville, Victoria 3052 (Australia); Parker, Michael W. [Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010 (Australia); Bio21 Molecular Science and Biotechnology Institute, 30 Flemington Road, University of Melbourne, Parkville, Victoria 3010 (Australia); St Vincents Institute, 9 Princes Street, Fitzroy, Victoria 3065 (Australia); Perugini, Matthew A. [Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria 3010 (Australia); Bio21 Molecular Science and Biotechnology Institute, 30 Flemington Road, University of Melbourne, Parkville, Victoria 3010 (Australia)

    2008-03-01

    Dihydrodipicolinate synthase (DHDPS), an enzyme in the lysine-biosynthetic pathway, is a promising target for antibiotic development against pathogenic bacteria. Here, the expression, purification, crystallization and preliminary diffraction analysis of DHDPS from C. botulinum are reported. In recent years, dihydrodipicolinate synthase (DHDPS; EC 4.2.1.52) has received considerable attention from both mechanistic and structural viewpoints. This enzyme, which is part of the diaminopimelate pathway leading to lysine, couples (S)-aspartate-β-semialdehyde with pyruvate via a Schiff base to a conserved active-site lysine. In this paper, the expression, purification, crystallization and preliminary X-ray diffraction analysis of DHDPS from Clostridium botulinum, an important bacterial pathogen, are presented. The enzyme was crystallized in a number of forms, predominantly using PEG precipitants, with the best crystal diffracting to beyond 1.9 Å resolution and displaying P4{sub 2}2{sub 1}2 symmetry. The unit-cell parameters were a = b = 92.9, c = 60.4 Å. The crystal volume per protein weight (V{sub M}) was 2.07 Å{sup 3} Da{sup −1}, with an estimated solvent content of 41%. The structure of the enzyme will help guide the design of novel therapeutics against the C. botulinum pathogen.

  20. A Preliminary Analysis of Reactor Performance Test (LOEP) for a Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyeonil; Park, Su-Ki [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    The final phase of commissioning is reactor performance test, which is to prove the integrated performance and safety of the research reactor at full power with fuel loaded such as neutron power calibration, Control Absorber Rod/Second Shutdown Rod drop time, InC function test, Criticality, Rod worth, Core heat removal with natural mechanism, and so forth. The last test will be safety-related one to assure the result of the safety analysis of the research reactor is marginal enough to be sure about the nuclear safety by showing the reactor satisfies the acceptance criteria of the safety functions such as for reactivity control, maintenance of auxiliaries, reactor pool water inventory control, core heat removal, and confinement isolation. After all, the fuel integrity will be ensured by verifying there is no meaningful change in the radiation levels. To confirm the performance of safety equipment, loss of normal electric power (LOEP), possibly categorized as Anticipated Operational Occurrence (AOO), is selected as a key experiment to figure out how safe the research reactor is before turning over the research reactor to the owner. This paper presents a preliminary analysis of the reactor performance test (LOEP) for a research reactor. The results showed how different the transient between conservative estimate and best estimate will look. Preliminary analyses have shown all probable thermal-hydraulic transient behavior of importance as to opening of flap valve, minimum critical heat flux ratio, the change of flow direction, and important values of thermal-hydraulic parameters.

  1. ANALYSIS OF GLOBAL INTEGRATION PROCESSES: SOUTH AFRICA, ASIA-PACIFIC REGION AND RUSSIA

    OpenAIRE

    Natalia Victorovna Kuznetsova, Natalia Alexandrovna Vorobeva

    2015-01-01

    The paper examines the problem of global integration processes in regions of Africa, Asia and Russia. Based on migration flows, estimation of integration indexes, we investigate the historical integration development of these regions and identify the important features for future international cooperation and integration. This article presents the preliminary results of the gravity model that we constructed using the features of Asia-Pacific region. We concluded that differences and similarit...

  2. UNEARTHING GLOBAL FINANCIAL INCLUSION LEVELS AND ANALYSIS OF FINANCIAL INCLUSION AS A MEDIATING FACTOR IN GLOBAL HUMAN DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Roshny Unnikrishnan

    2015-04-01

    Full Text Available This study is a result of the author’s inquisition to unearth the current values of Global Financial Inclusion and its relationship with economic growth measured by Gross Domestic product(GDP and human development measured by United Nations Human Development Index (HDI. The Financial Inclusion (FI levels are measured using Index for Financial Inclusion .The relationship between GDP and HDI with FI as mediator, using multiple regression, is validated on a global level based on data of 162 countries for the year 2011. An overall global mediation analysis is undertaken to establish Financial Inclusion as a mediating factor and partial mediation on human development is validated. The study is valid and unique in the global context of income inequality prevailing in developed, developing and underdeveloped countries as it validates the argument that an impressive GDP performance does not ensure equity in economic growth.

  3. Preliminary design and thermal analysis of device for finish cooling Jaffa biscuits in a.d. 'Jaffa'- Crvenka

    Directory of Open Access Journals (Sweden)

    Salemović Duško R.

    2015-01-01

    Full Text Available In this paper preliminary design of device for finish cooling chocolate topping of biscuits in A.D. 'Jaffa'- Crvenka was done. The proposed preliminary design followed by the required technological process of finish cooling biscuits and required parameters of process which was supposed to get and which represented part of project task. Thermal analysis was made and obtained percentage error between surface contact of the air and chocolate topping, obtained from heat balance and geometrical over proposed preliminary design, wasn't more than 0.67%. This is a preliminary design completely justified because using required length of belt conveyor receive required temperature of chocolate topping at the end of the cooling process.

  4. Mini-DIAL system measurements coupled with multivariate data analysis to identify TIC and TIM simulants: preliminary absorption database analysis.

    Science.gov (United States)

    Gaudio, P.; Malizia, A.; Gelfusa, M.; Martinelli, E.; Di Natale, C.; Poggi, L. A.; Bellecci, C.

    2017-01-01

    Nowadays Toxic Industrial Components (TICs) and Toxic Industrial Materials (TIMs) are one of the most dangerous and diffuse vehicle of contamination in urban and industrial areas. The academic world together with the industrial and military one are working on innovative solutions to monitor the diffusion in atmosphere of such pollutants. In this phase the most common commercial sensors are based on “point detection” technology but it is clear that such instruments cannot satisfy the needs of the smart cities. The new challenge is developing stand-off systems to continuously monitor the atmosphere. Quantum Electronics and Plasma Physics (QEP) research group has a long experience in laser system development and has built two demonstrators based on DIAL (Differential Absorption of Light) technology could be able to identify chemical agents in atmosphere. In this work the authors will present one of those DIAL system, the miniaturized one, together with the preliminary results of an experimental campaign conducted on TICs and TIMs simulants in cell with aim of use the absorption database for the further atmospheric an analysis using the same DIAL system. The experimental results are analysed with standard multivariate data analysis technique as Principal Component Analysis (PCA) to develop a classification model aimed at identifying organic chemical compound in atmosphere. The preliminary results of absorption coefficients of some chemical compound are shown together pre PCA analysis.

  5. Preliminary Nuclear Analysis for the HANARO Fuel Element with Burnable Absorber

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Chul Gyo; Kim, So Young; In, Won Ho [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    Burnable absorber is used for reducing reactivity swing and power peaking in high performance research reactors. Development of the HANARO fuel element with burnable absorber was started in the U-Mo fuel development program at HANARO, but detailed full core analysis was not performed because the current HANARO fuel management system is uncertain to analysis the HANARO core with burnable absorber. A sophisticated reactor physics system is required to analysis the core. The McCARD code was selected and the detailed McCARD core models, in which the basic HANARO core model was developed by one of the McCARD developers, are used in this study. The development of nuclear fuel requires a long time and correct developing direction especially by the nuclear analysis. This paper presents a preliminary nuclear analysis to promote the fuel development. Based on the developed fuel, the further nuclear analysis will improve reactor performance and safety. Basic nuclear analysis for the HANARO and the AHR were performed for getting the proper fuel elements with burnable absorber. Addition of 0.3 - 0.4% Cd to the fuel meat is promising for the current HANARO fuel element. Small addition of burnable absorber may not change any fuel characteristics of the HANARO fuel element, but various basic tests and irradiation tests at the HANARO core are required.

  6. Treatment by gliding arc of epoxy resin: preliminary analysis of surface modifications

    Science.gov (United States)

    Faubert, F.; Wartel, M.; Pellerin, N.; Pellerin, S.; Cochet, V.; Regnier, E.; Hnatiuc, B.

    2016-12-01

    Treatments with atmospheric pressure non-thermal plasma are easy to implement and inexpensive. Among them gliding arc (GlidArc) remains rarely used in surface treatment of polymers. However, it offers economic and flexible way to treat quickly large areas. In addition the choice of carrier gas makes it possible to bring the active species and other radicals allowing different types of grafting and functionalization of the treated surfaces, for example in order to apply for anti-biofouling prevention. This preliminary work includes analysis of the surface of epoxy resins by infrared spectroscopy: the different affected chemical bonds were studied depending on the duration of treatment. The degree of oxidation (the C/O ratio) is obtained by X-ray microanalysis and contact angle analysis have been performed to determinate the wettability properties of the treated surface. A spectroscopic study of the plasma allows to determine the possible active species in the different zones of the discharge.

  7. Los Alamos National Laboratory corregated metal pipe saw facility preliminary safety analysis report. Volume I

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1990-09-19

    This Preliminary Safety Analysis Report addresses site assessment, facility design and construction, and design operation of the processing systems in the Corrugated Metal Pipe Saw Facility with respect to normal and abnormal conditions. Potential hazards are identified, credible accidents relative to the operation of the facility and the process systems are analyzed, and the consequences of postulated accidents are presented. The risk associated with normal operations, abnormal operations, and natural phenomena are analyzed. The accident analysis presented shows that the impact of the facility will be acceptable for all foreseeable normal and abnormal conditions of operation. Specifically, under normal conditions the facility will have impacts within the limits posted by applicable DOE guidelines, and in accident conditions the facility will similarly meet or exceed the requirements of all applicable standards. 16 figs., 6 tabs.

  8. Preliminary Uncertainty Analysis for SMART Digital Core Protection and Monitoring System

    Energy Technology Data Exchange (ETDEWEB)

    Koo, Bon Seung; In, Wang Kee; Hwang, Dae Hyun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2012-05-15

    The Korea Atomic Energy Research Institute (KAERI) developed on-line digital core protection and monitoring systems, called SCOPS and SCOMS as a part of SMART plant protection and monitoring system. SCOPS simplified the protection system by directly connecting the four RSPT signals to each core protection channel and eliminated the control element assembly calculator (CEAC) hardware. SCOMS adopted DPCM3D method in synthesizing core power distribution instead of Fourier expansion method being used in conventional PWRs. The DPCM3D method produces a synthetic 3-D power distribution by coupling a neutronics code and measured in-core detector signals. The overall uncertainty analysis methodology which is used statistically combining uncertainty components of SMART core protection and monitoring system was developed. In this paper, preliminary overall uncertainty factors for SCOPS/SCOMS of SMART initial core were evaluated by applying newly developed uncertainty analysis method

  9. Preliminary cladistic analysis of genera of the cestode order Trypanorhyncha Diesing, 1863.

    Science.gov (United States)

    Beveridge, I; Campbell, R A; Palm, H W

    1999-01-01

    A preliminary cladistic analysis was carried out on the 49 currently recognised genera of the order Trypanorhyncha. Forty-four characters were analysed; a functional outgroup was used for scolex and strobilar characters, while Nybelinia was utilised to polarise characters related to the rhyncheal system. Eight well-resolved clades were evident in the resultant cladogram, which is compared with existing phenetic classifications. An analysis of families resulted in a similar clustering of taxa to that observed in the case of the genera. The results suggest that two key characters used in existing classifications, namely the presence of sensory fossettes on the bothridia and the development of atypical heteroacanth and poeciloacanth armatures from typical heteroacanth armatures, have occurred on several occasions. Some clades provide support for the arrangements used in current classifications. Suggestions are made for future avenues of research which might provide more robust phylogenetic data for the Trypanorhyncha.

  10. Preliminary Evaluation of MapReduce for High-Performance Climate Data Analysis

    Science.gov (United States)

    Duffy, Daniel Q.; Schnase, John L.; Thompson, John H.; Freeman, Shawn M.; Clune, Thomas L.

    2012-01-01

    MapReduce is an approach to high-performance analytics that may be useful to data intensive problems in climate research. It offers an analysis paradigm that uses clusters of computers and combines distributed storage of large data sets with parallel computation. We are particularly interested in the potential of MapReduce to speed up basic operations common to a wide range of analyses. In order to evaluate this potential, we are prototyping a series of canonical MapReduce operations over a test suite of observational and climate simulation datasets. Our initial focus has been on averaging operations over arbitrary spatial and temporal extents within Modern Era Retrospective- Analysis for Research and Applications (MERRA) data. Preliminary results suggest this approach can improve efficiencies within data intensive analytic workflows.

  11. Dimensions of Human-Work Domain Interaction: A Preliminary Analysis for the Design of a Corporate Digital Library.

    Science.gov (United States)

    Xie, Hong

    2003-01-01

    Applies the cognitive system engineering approach to investigate human-work interaction at a corporate setting. Reports preliminary analysis of data collected from diary analysis and interview of 20 subjects. Results identify three dimensions for each of four interactive activities involved in human-work interaction and their relationships.…

  12. Analysis and Outlook of Global Rare Earth Market

    Institute of Scientific and Technical Information of China (English)

    XIONG Jiaqi

    2008-01-01

    @@ When enterd into 21st century,global rare earth market exhibits pleasing situation in recent years,profitig from fast development of global economy.China represented nearly 60% of global rare earth consumption in 2007.Rare earth consumtion in five advanced materisls including permanent magnets,polishing powder,hydrogen storage materisls,fluorescent materials and auto catalysts accounted for 60% of the tutal consumption.

  13. Global analysis of the protection status of the world's forests

    DEFF Research Database (Denmark)

    Schmitt, Christine B.; Burgess, Neil David; Coad, Lauren

    2009-01-01

    on forest distribution. Using the 2008 World Database on Protected Areas, percentage forest cover protection was calculated globally, within forest types, realms and ecoregions, and within selected areas of global conservation importance. At the 10% tree cover threshold, global forest cover was 39 million....... Considering their biodiversity importance, forest protection within global priority areas was insufficient, e.g., median protection of 8.4% in biodiversity hotspots (IUCN I-IV). Results have policy relevance in terms of the target of the Convention on Biological Diversity (CBD), reconfirmed in 2008...

  14. Advancing Collaborative Climate Studies through Globally Distributed Geospatial Analysis

    Science.gov (United States)

    Singh, R.; Percivall, G.

    2009-12-01

    Infrastructure and the broader GEOSS architecture. Of specific interest to this session is the work on geospatial workflows and geo-processing and data discovery and access. CCIP demonstrates standards-based interoperability between geospatial applications in the service of Climate Change analysis. CCIP is planned to be a yearly exercise. It consists of a network of online data services (WCS, WFS, SOS), analysis services (WPS, WCPS, WMS), and clients that exercise those services. In 2009, CCIP focuses on Australia, and the initial application of existing OGC services to climate studies. The results of the 2009 CCIP will serve as requirements for more complex geo-processing services to be developed for CCIP 2010. The benefits of CCIP include accelerating the implementation of the GCOS, and building confidence that implementations using multi-vendor interoperable technologies can help resolve vexing climate change questions. AIP-2: Architecture Implementation Pilot, Phase 2 CCIP: Climate Challenge Integration Plugfest GEO: Group on Earth Observations GEOSS: Global Earth Observing System of Systems GCOS: Global Climate Observing System OGC: Open Geospatial Consortium SOS: Sensor Observation Service WCS: Web Coverage Service WCPS: Web Coverage Processing Service WFS: Web Feature Service WMS: Web Mapping Service

  15. Analysis of the development of global capture fishery and aquaculture production

    OpenAIRE

    Algayd, Abdelhamid Alhadi

    2011-01-01

    Global production from capture fisheries and aquaculture and the food fish supply is currently the highest on record and remains very significant for global food security. This study is focused on the contribution of the aquaculture to the global production of fish, crustaceans, molluscs, and other aquatic animals in the short-time observation from 2000- 2008. The aim of the presented PhD. Thesis title "Analysis of The Development of Global Capture Fish and Aquaculture Production (200-2008)" ...

  16. Preliminary failure modes and effects analysis on Korean HCCR TBS to be tested in ITER

    Energy Technology Data Exchange (ETDEWEB)

    Ahn, Mu-Young, E-mail: myahn74@nfri.re.kr [National Fusion Research Institute, Daejeon (Korea, Republic of); Cho, Seungyon [National Fusion Research Institute, Daejeon (Korea, Republic of); Jin, Hyung Gon; Lee, Dong Won [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Park, Yi-Hyun; Lee, Youngmin [National Fusion Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    Highlights: • Postulated initiating events are identified through failure modes and effects analysis on the current HCCR TBS design. • A set of postulated initiating events are selected for consideration of deterministic analysis. • Accident evolutions on the selected postualted initiating events are qualitatively described for deterministic analysis. - Abstract: Korean Helium cooled ceramic reflector (HCCR) Test blanket system (TBS), which comprises Test blanket module (TBM) and ancillary systems in various locations of ITER building, is operated at high temperature and pressure with decay heat. Therefore, safety is utmost concern in design process and it is required to demonstrate that the HCCR TBS is designed to comply with the safety requirements and guidelines of ITER. Due to complexity of the system with many interfaces with ITER, a systematic approach is necessary for safety analysis. This paper presents preliminary failure modes and effects analysis (FMEA) study performed for the HCCR TBS. FMEA is a systematic methodology in which failure modes for components in the system and their consequences are studied from the bottom-up. Over eighty failure modes have been investigated on the HCCR TBS. The failure modes that have similar consequences are grouped as postulated initiating events (PIEs) and total seven reference accident scenarios are derived from FMEA study for deterministic accident analysis. Failure modes not covered here due to evolving design of the HCCR TBS and uncertainty in maintenance procedures will be studied further in near future.

  17. A distributed analysis of Human impact on global sediment dynamics

    Science.gov (United States)

    Cohen, S.; Kettner, A.; Syvitski, J. P.

    2012-12-01

    Understanding riverine sediment dynamics is an important undertaking for both socially-relevant issues such as agriculture, water security and infrastructure management and for scientific analysis of landscapes, river ecology, oceanography and other disciplines. Providing good quantitative and predictive tools in therefore timely particularly in light of predicted climate and landuse changes. Ever increasing human activity during the Anthropocene have affected sediment dynamics in two major ways: (1) an increase is hillslope erosion due to agriculture, deforestation and landscape engineering and (2) trapping of sediment in dams and other man-made reservoirs. The intensity and dynamics between these man-made factors vary widely across the globe and in time and are therefore hard to predict. Using sophisticated numerical models is therefore warranted. Here we use a distributed global riverine sediment flux and water discharge model (WBMsed) to compare a pristine (without human input) and disturbed (with human input) simulations. Using these 50 year simulations we will show and discuss the complex spatial and temporal patterns of human effect on riverine sediment flux and water discharge.

  18. Dynamic global sensitivity analysis in bioreactor networks for bioethanol production.

    Science.gov (United States)

    Ochoa, M P; Estrada, V; Di Maggio, J; Hoch, P M

    2016-01-01

    Dynamic global sensitivity analysis (GSA) was performed for three different dynamic bioreactor models of increasing complexity: a fermenter for bioethanol production, a bioreactors network, where two types of bioreactors were considered: aerobic for biomass production and anaerobic for bioethanol production and a co-fermenter bioreactor, to identify the parameters that most contribute to uncertainty in model outputs. Sobol's method was used to calculate time profiles for sensitivity indices. Numerical results have shown the time-variant influence of uncertain parameters on model variables. Most influential model parameters have been determined. For the model of the bioethanol fermenter, μmax (maximum growth rate) and Ks (half-saturation constant) are the parameters with largest contribution to model variables uncertainty; in the bioreactors network, the most influential parameter is μmax,1 (maximum growth rate in bioreactor 1); whereas λ (glucose-to-total sugars concentration ratio in the feed) is the most influential parameter over all model variables in the co-fermentation bioreactor.

  19. The CT14 Global Analysis of Quantum Chromodynamics

    CERN Document Server

    Dulat, Sayipjamal; Gao, Jun; Guzzi, Marco; Huston, Joey; Nadolsky, Pavel; Pumplin, Jon; Schmidt, Carl; Stump, Daniel; Yuan, C P

    2015-01-01

    We present new parton distribution functions (PDFs) up to next-to-next-to-leading order (NNLO) from the CTEQ-TEA global analysis of quantum chromodynamics. These differ from previous CT PDFs in several respects, including the use of data from LHC experiments and the new D0 charged lepton rapidity asymmetry data, as well as the use of more flexible parametrization of PDFs that, in particular, allows a better fit to different combinations of quark flavors. Predictions for important LHC processes, especially Higgs boson production at 13 TeV, are presented. These CT14 PDFs include a central set and error sets in the Hessian representation. For completeness, we also present the CT14 PDFs determined at the leading order (LO) and the next-to-leading order (NLO) in QCD. Besides these general-purpose PDF sets, we provide a series of (N)NLO sets with various $\\alpha_s$ values and additional sets in heavy-quark scheme with up to 3, 4, and 6 active flavors.

  20. Global secretome analysis identifies novel mediators of bone metastasis

    Institute of Scientific and Technical Information of China (English)

    Mario Andres Blanco; Gary LeRoy; Zia Khan; Ma(s)a Ale(c)kovi(c); Barry M Zee; Benjamin A Garcia; Yibin Kang

    2012-01-01

    Bone is the one of the most common sites of distant metastasis of solid tumors.Secreted proteins are known to influence pathological interactions between metastatic cancer cells and the bone stroma.To comprehensively profile secreted proteins associated with bone metastasis,we used quantitative and non-quantitative mass spectrometry to globally analyze the secretomes of nine cell lines of varying bone metastatic ability from multiple species and cancer types.By comparing the secretomes of parental cells and their bone metastatic derivatives,we identified the secreted proteins that were uniquely associated with bone metastasis in these cell lines.We then incorporated bioinformatic analyses of large clinical metastasis datasets to obtain a list of candidate novel bone metastasis proteins of several functional classes that were strongly associated with both clinical and experimental bone metastasis.Functional validation of selected proteins indicated that in vivo bone metastasis can be promoted by high expression of (1) the salivary cystatins CST1,CST2,and CST4; (2) the plasminogen activators PLAT and PLAU; or (3) the collagen functionality proteins PLOD2 and COL6A1.Overall,our study has uncovered several new secreted mediators of bone metastasis and therefore demonstrated that secretome analysis is a powerful method for identification of novel biomarkers and candidate therapeutic targets.

  1. Nitrogen Additions and Microbial Biomass: A Global Meta-analysis

    Science.gov (United States)

    Treseder, K. K.

    2008-12-01

    Nitrogen (N) enrichment is an element of global change that could influence the growth and abundance of many organisms. In this meta-analysis, I synthesized responses of microbial biomass to N additions in 82 published field studies. I hypothesized that the biomass of fungi, bacteria, or the microbial community as a whole would be altered under N additions. I also predicted that changes in biomass would parallel changes in soil CO2 emissions. Microbial biomass declined 15% on average under N fertilization, but fungi and bacteria were not significantly altered in studies that examined each group separately. Moreover, declines in abundance of microbes and fungi were more evident in studies of longer durations and with higher total amounts of N added. In addition, responses of microbial biomass to N fertilization were significantly correlated with responses of soil CO2 emissions. There were no significant effects of biomes, fertilizer types, ambient N deposition rates, or methods of measuring biomass. Altogether, these results suggest that N enrichment could reduce microbial biomass in many ecosystems, with corresponding declines in soil CO2 emissions.

  2. The Development of a Long-Term, Continually Updated Global Solar Resource at 10 km Resolution: Preliminary Results From Test Processing and Continuing Plans

    Science.gov (United States)

    Stackhouse, P.; Perez, R.; Sengupta, M.; Knapp, K.; Cox, Stephen; Mikovitz, J. Colleen; Zhang, T.; Hemker, K.; Schlemmer, J.; Kivalov, S.

    2014-01-01

    Background: Considering the likelihood of global climatic weather pattern changes and the global competition for energy resources, there is an increasing need to provide improved and continuously updated global Earth surface solar resource information. Toward this end, a project was funded under the NASA Applied Science program involving the National Aeronautics and Space Administration (NASA) Langley Research Center (LaRC), National Renewable Energy Laboratory (NREL), the State University of New York/Albany (SUNY) and the NOAA National Climatic Data Center (NCDC) to provide NREL with a global long-term advanced global solar mapping production system for improved depiction of historical solar resources and variability and to provide a mechanism for continual updates of solar resource information. This new production system is made possible by the efforts of NOAA and NASA to completely reprocess the International Satellite Cloud Climatology Project (ISCCP) data set that provides satellite visible and infrared radiances together with retrieved cloud and surface properties on a 3-hourly basis beginning from July 1983. The old version of the ISCCP data provided this information for all the world TMs available geosynchronous satellite systems and NOAA TMs AVHRR data sets at a 30 km effective resolution. This new version aims to provide a new and improved satellite calibration at an effective 10 km resolution. Thus, working with SUNY, NASA will develop and test an improved production system that will enable NREL to continually update the Earth TM solar resource. Objective and Methods: In this presentation, we provide a general overview of this project together with samples of the new solar irradiance mapped data products and comparisons to surface measurements at various locations across the world. An assessment of the solar resource values relative to calibration uncertainty and assumptions are presented. Errors resulting assumptions in snow cover and background aerosol

  3. Expression, purification, crystallization and preliminary crystallographic analysis of the proliferation-associated protein Ebp1

    Energy Technology Data Exchange (ETDEWEB)

    Kowalinski, Eva; Bange, Gert; Wild, Klemens; Sinning, Irmgard, E-mail: irmi.sinning@bzh.uni-heidelberg.de [Heidelberg University Biochemistry Center, INF 328, D-69120 Heidelberg (Germany)

    2007-09-01

    Preliminary X-ray analysis of the proliferation-associated protein Ebp1 from Homo sapiens is provided. ErbB-3-binding protein 1 (Ebp1) is a member of the family of proliferation-associated 2G4 proteins (PA2G4s) and plays a role in cellular growth and differentiation. Ligand-induced activation of the transmembrane receptor ErbB3 leads to dissociation of Ebp1 from the receptor in a phosphorylation-dependent manner. The non-associated protein is involved in transcriptional and translational regulation in the cell. Here, the overexpression, purification, crystallization and preliminary crystallographic studies of Ebp1 from Homo sapiens are reported. Initially observed crystals were improved by serial seeding to single crystals suitable for data collection. The optimized crystals belong to the tetragonal space group P4{sub 1}2{sub 1}2 or P4{sub 3}2{sub 1}2 and diffracted to a resolution of 1.6 Å.

  4. Global methaemoglobinaemia research output (1940-2013): a bibliometric analysis.

    Science.gov (United States)

    Zyoud, Sa'ed H; Al-Jabi, Samah W; Sweileh, Waleed M; Al-Khalil, Suleiman; Alqub, Malik; Awang, Rahmat

    2015-01-01

    Bibliometric studies, which involve the use of statistical methods, are increasingly being used for research assessment. A bibliometric analysis was conducted to evaluate the publication pattern of methaemoglobinaemia research output at the global level based on the Scopus database. We analysed selected documents with "methemoglobinemia", or "methaemoglobinaemia" as a part of the title and reported the following parameters: trends of publication output, country of publication, journal pattern, collaborative measures, citations pattern, and institute productivity. A total of 1770 articles were published worldwide. The time trend for the number of articles showed an increase after 2000. The highest number of articles related to methaemoglobinaemia was from the USA (24.8 %), followed distantly by the UK (4.5 %), India (3.7 %), and France (3.7 %). No data related to methaemoglobinaemia were published from 152 countries. The total number of citations at the date of data collection was 10,080, with an average of 5.7 citations per document. The USA and UK had the highest h-index of 31 and 14, respectively, and six countries had an h-index of 9-14. It is notable that Canada was ranked eighth in the number of publications but fourth in h-index and India was ranked third in the number of publications but eighth in h-index. Furthermore, Canada produced the most internationally collaborated papers out of the total number of publications for each country (16.1 %), followed by the UK (13.9 %). This bibliometric analysis provides data contributing to a better understanding of the methaemoglobinaemia research field. The number of publications on methaemoglobinaemia increased significantly after 2000. The USA was the most productive country as measured by total publications. The USA and UK achieved the highest h-index in the field of methaemoglobinaemia research, signifying a higher quality of research than other countries.

  5. Understanding earth system models: how Global Sensitivity Analysis can help

    Science.gov (United States)

    Pianosi, Francesca; Wagener, Thorsten

    2017-04-01

    Computer models are an essential element of earth system sciences, underpinning our understanding of systems functioning and influencing the planning and management of socio-economic-environmental systems. Even when these models represent a relatively low number of physical processes and variables, earth system models can exhibit a complicated behaviour because of the high level of interactions between their simulated variables. As the level of these interactions increases, we quickly lose the ability to anticipate and interpret the model's behaviour and hence the opportunity to check whether the model gives the right response for the right reasons. Moreover, even if internally consistent, an earth system model will always produce uncertain predictions because it is often forced by uncertain inputs (due to measurement errors, pre-processing uncertainties, scarcity of measurements, etc.). Lack of transparency about the scope of validity, limitations and the main sources of uncertainty of earth system models can be a strong limitation to their effective use for both scientific and decision-making purposes. Global Sensitivity Analysis (GSA) is a set of statistical analysis techniques to investigate the complex behaviour of earth system models in a structured, transparent and comprehensive way. In this presentation, we will use a range of examples across earth system sciences (with a focus on hydrology) to demonstrate how GSA is a fundamental element in advancing the construction and use of earth system models, including: verifying the consistency of the model's behaviour with our conceptual understanding of the system functioning; identifying the main sources of output uncertainty so to focus efforts for uncertainty reduction; finding tipping points in forcing inputs that, if crossed, would bring the system to specific conditions we want to avoid.

  6. Global Analysis of Heat Shock Response in Desulfovibrio vulgaris Hildenborough.

    Energy Technology Data Exchange (ETDEWEB)

    Chhabra, S.R.; He, Q.; Huang, K.H.; Gaucher, S.P.; Alm, E.J.; He,Z.; Hadi, M.Z.; Hazen, T.C.; Wall, J.D.; Zhou, J.; Arkin, A.P.; Singh, A.K.

    2005-09-16

    Desulfovibrio vulgaris Hildenborough belongs to a class ofsulfate-reducing bacteria (SRB) and is found ubiquitously in nature.Given the importance of SRB-mediated reduction for bioremediation ofmetal ion contaminants, ongoing research on D. vulgaris has been in thedirection of elucidating regulatory mechanisms for this organism under avariety of stress conditions. This work presents a global view of thisorganism's response to elevated growth temperature using whole-celltranscriptomics and proteomics tools. Transcriptional response (1.7-foldchange or greater; Z>1.5) ranged from 1,135 genes at 15 min to 1,463genes at 120 min for a temperature up-shift of 13oC from a growthtemperature of 37oC for this organism and suggested both direct andindirect modes of heat sensing. Clusters of orthologous group categoriesthat were significantly affected included posttranslationalmodifications; protein turnover and chaperones (up-regulated); energyproduction and conversion (down-regulated), nucleotide transport,metabolism (down-regulated), and translation; ribosomal structure; andbiogenesis (down-regulated). Analysis of the genome sequence revealed thepresence of features of both negative and positive regulation whichincluded the CIRCE element and promoter sequences corresponding to thealternate sigma factors ?32 and ?54. While mechanisms of heat shockcontrol for some genes appeared to coincide with those established forEscherichia coli and Bacillus subtilis, the presence of unique controlschemes for several other genes was also evident. Analysis of proteinexpression levels using differential in-gel electrophoresis suggestedgood agreement with transcriptional profiles of several heat shockproteins, including DnaK (DVU0811), HtpG (DVU2643), HtrA (DVU1468), andAhpC (DVU2247). The proteomics study also suggested the possibility ofposttranslational modifications in the chaperones DnaK, AhpC, GroES(DVU1977), and GroEL (DVU1976) and also several periplasmic ABCtransporters.

  7. An Analysis of Globalization and Higher Education in Malaysia

    Science.gov (United States)

    Arokiasamy, Anantha Raj A.

    2011-01-01

    This study aims to examine the impact of globalization on private higher education in Malaysia. The impact of globalization and the development of knowledge-based economy have caused much dramatic change to the character and functions of higher education in Malaysia. The major trend is the reforming and restructuring of private higher education in…

  8. A Preliminary Model Study of the Large-Scale Seasonal Cycle in Bottom Pressure Over the Global Ocean

    Science.gov (United States)

    Ponte, Rui M.

    1998-01-01

    Output from the primitive equation model of Semtner and Chervin is used to examine the seasonal cycle in bottom pressure (Pb) over the global ocean. Effects of the volume-conserving formulation of the model on the calculation Of Pb are considered. The estimated seasonal, large-scale Pb signals have amplitudes ranging from less than 1 cm over most of the deep ocean to several centimeters over shallow, boundary regions. Variability generally increases toward the western sides of the basins, and is also larger in some Southern Ocean regions. An oscillation between subtropical and higher latitudes in the North Pacific is clear. Comparison with barotropic simulations indicates that, on basin scales, seasonal Pb variability is related to barotropic dynamics and the seasonal cycle in Ekman pumping, and results from a small, net residual in mass divergence from the balance between Ekman and Sverdrup flows.

  9. Using a global ocean circulation model to conduct a preliminary risk assessment of oil spills in the Atlantic

    Science.gov (United States)

    Jacobs, Zoe; Popova, Katya; Hirschi, Joel; Coward, Andrew; Yool, Andrew; van Gennip, Simon; Anifowose, Babtunde; Harrington-Missin, Liam

    2017-04-01

    Although oil blowouts from deep-water drilling happen very rarely, they can cause catastrophic damage to the environment. Despite such potentially high impacts, relatively little research effort has gone into understanding subsurface oil plumes in the deep ocean. In this study, we demonstrate the significance of this problem and offer potential solutions using a novel approach based on a leading-edge, high-resolution global ocean circulation model. We present examples demonstrating: (a) the importance of ocean circulation in the propagation of oil spills; and (b) likely circulation footprints for oil spills at four key locations in the Atlantic Ocean that exist in different circulation regimes - the shelves of Brazil, the Gulf of Guinea, the Gulf of Mexico and the Faroe-Shetland Channel. In order to quantify the variability at each site on seasonal timescales, interannual timescales and at different depths, we utilize the Modified Hausdorff Distance (MHD), which is a shape-distance metric that measures the similarity between two shapes. The scale of the footprints across the four focus locations varies considerably and is determined by the main circulation features in their vicinity. For example, the hypothetical oil plume can be affected by variations in the speed and location of a particular current (e.g. Brazil Current at the Brazilian shelf site) or be influenced by different currents entirely depending on the release depth, month and year (e.g. Angola Current or Southern Equatorial Current at the Gulf of Guinea site). Overall, our results demonstrate the need to use state of the art global, or basin-scale, ocean circulation models when assessing the environmental impacts of proposed oil drilling activities.

  10. Analysis of Diversity-Preserving Mechanisms for Global Exploration

    DEFF Research Database (Denmark)

    Friedrich, Tobias; Oliveto, Pietro S.; Sudholt, Dirk

    2009-01-01

    Maintaining diversity is important for the performance of evolutionary algorithms. Diversity-preserving mechanisms can enhance global exploration of the search space and enable crossover to find dissimilar individuals for recombination. We focus on the global exploration capabilities of mutation......-based algorithms. Using a simple bimodal test function and rigorous runtime analyses, we compare well-known diversity-preserving mechanisms like deterministic crowding, fitness sharing, and others with a plain algorithm without diversification. We show that diversification is necessary for global exploration...

  11. Globalization: political and economic and sociological analysis of cultures

    Directory of Open Access Journals (Sweden)

    O. S. Babicheva

    2016-10-01

    Full Text Available In the presented article the authors examine the political and economic and cultural situation in the world in the context of globalization. Special priority is accorded to the coverage of political and economic situation in the world. Because, the twentieth century has demonstrated the power of supranational military- political blocs, the possibility of coalitions of control groups, continental and regional associations, international organizations. At the end of the twentieth century, the contours of «world government» have outlined (world of the Board: some international organizations started performing important political integration functions. The value of the global division of labor has increased in the economic sphere, the role of transnational corporations has increased, which have become powerful forces in the world economy. Having lost the national roots, such corporations operate globally, using local resources and subsidies. The authors noted that the trend of globalization had its influence on the culture as well .Media unites peoples and continents , informing millions of people about the events in different parts of the world , attracting them to various cultural experiences , traditions and customs of exotic tribes and nationalities .Today, there is no doubt, that the desire to solve global problems that affect interests of the peoples of all continents leads to the formation of the world humanistic consciousness. It is proved that during a long period of time the phenomenon of globalization was considered in socio-political theories mainly from the point of economic centrism. As It is the economic sphere, in which the globalization centrism was mostly discovered. The basic classical concepts developed within the economic centrism: theory of imperialism, dependency theory, world system theory. It was marked that the presented economic-centric pictures of globalization cannot explain the cultural-historical diversity of the

  12. Global analysis of Ivlev's type predator-prey dynamic systems

    Institute of Scientific and Technical Information of China (English)

    XIAO Hai-bin

    2007-01-01

    Consider a class of Ivlev's type predator-prey dynamic systems with prey and predator both having linear density restricts. By using the qualitative methods of ODE,the global stability of positive equilibrium and existence and uniqueness of non-small amplitude stable limit cycle are obtained. Especially under certain conditions, it shows that existence and uniqueness of non-small amplitude stable limit cycle is equivalent to the local un-stability of positive equilibrium and the local stability of positive equilibrium implies its global stability. That is to say, the global dynamic of the system is entirely determined by the local stability of the positive equilibrium.

  13. Preliminary Analysis on the Relative Solution Space Sizes for MTSP with Genetic Algorithm

    Science.gov (United States)

    Hao, Junling

    It is well known that the chromosome design is pivotal to solve the multiple traveling salesman problems with genetic algorithm. A well-designed chromosome coding can eliminate or reduce the redundant solutions. One chromosome and two chromosome design methods and a recently proposed two-part chromosome design are firstly introduced in this paper. Then the preliminary quantitative comparison analysis of the solution spaces of three different chromosome design methods is presented when the number of cities is linear with the travelers. The concept of relative solution space is proposed in order to compare the relative size of the solution spaces. The solution space of two-part chromosome design is much smaller than those of the traditional chromosome design. The result given in this paper provides a good guideline for the possible algorithmic design and engineering applications.

  14. Crystallization and preliminary X-ray analysis of alginate importer from Sphingomonas sp. A1.

    Science.gov (United States)

    Maruyama, Yukie; Itoh, Takafumi; Nishitani, Yu; Mikami, Bunzo; Hashimoto, Wataru; Murata, Kousaku

    2012-03-01

    Sphingomonas sp. A1 directly incorporates alginate polysaccharides through a 'superchannel' comprising a pit on the cell surface, alginate-binding proteins in the periplasm and an ABC transporter (alginate importer) in the inner membrane. Alginate importer, consisting of four subunits, AlgM1, AlgM2 and two molecules of AlgS, was crystallized in the presence of the binding protein AlgQ2. Preliminary X-ray analysis showed that the crystal diffracted to 3.3 Å resolution and belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 72.5, b = 136.8, c = 273.3 Å, suggesting the presence of one complex in the asymmetric unit.

  15. ANSI/ASHRAE/IES Standard 90.1-2013 Preliminary Determination: Qualitative Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Halverson, Mark A.; Hart, Reid; Athalye, Rahul A.; Rosenberg, Michael I.; Richman, Eric E.; Winiarski, David W.

    2014-03-01

    Section 304(b) of the Energy Conservation and Production Act (ECPA), as amended, requires the Secretary of Energy to make a determination each time a revised version of ASHRAE Standard 90.1 is published with respect to whether the revised standard would improve energy efficiency in commercial buildings. When the U.S. Department of Energy (DOE) issues an affirmative determination on Standard 90.1, states are statutorily required to certify within two years that they have reviewed and updated the commercial provisions of their building energy code, with respect to energy efficiency, to meet or exceed the revised standard. This report provides a preliminary qualitative analysis of all addenda to ANSI/ASHRAE/IES Standard 90.1-2010 (referred to as Standard 90.1-2010 or 2010 edition) that were included in ANSI/ASHRAE/IES Standard 90.1-2013 (referred to as Standard 90.1-2013 or 2013 edition).

  16. Crystallization and preliminary X-ray analysis of Rv1674c from Mycobacterium tuberculosis

    Science.gov (United States)

    Li, Jincheng; Wang, Xudong; Gong, Weimin; Niu, Chunyan; Zhang, Min

    2015-01-01

    Adaptations to hypoxia play an important role in Mycobacterium tuberculosis pathogenesis. Rv0324, which contains an HTH DNA-binding domain and a rhodanese domain, is one of the key transcription regulators in response to hypoxia. M. tuberculosis Rv1674c is a homologue of Rv0324. To understand the interdomain interaction and regulation of the HTH domain and the rhodanese domain, recombinant Rv1674c protein was purified and crystallized by the vapour-diffusion method. The crystals diffracted to 2.25 Å resolution. Preliminary diffraction analysis suggests that the crystals belonged to space group P3121 or P3221, with unit-cell parameters a = b = 67.8, c = 174.5 Å, α = β = 90, γ = 120°. The Matthews coefficient was calculated to be 2.44 Å3 Da−1, assuming that the crystallographic asymmetric unit contains two protein molecules. PMID:25760714

  17. Preliminary phytochemical analysis, antibacterial, antifungal and anticandidal activities of successive extracts of Crossandra infundibuliformis

    Institute of Scientific and Technical Information of China (English)

    MadhumithaG; SaralAM

    2011-01-01

    Objective:To investigate the phytochemical, antibacterial, antifungal and anticandidal activity of successive extracts of Crossandra infundibuliformis (Acanthaceae) leaves. Methods:Preliminary screening on the presence of alkaloids, saponins, phytosterols, phenolic compounds, flavanoids, tannins, carbohydrates, terpenoids, oils and fats were carried out by phytochemical analysis. The antibacterial, antifungal and anticandidal activities were done by agar well diffusion technique. Results:The successive extracts have an array of chemical constituents and the MIC values of antibacterial activity ranges from 0.007 8 to 0.015 0μg/mL. In case of antifungal and anticandidal activities the MIC values were between 0.125 and 0.250μg/mL. Conclusions:These findings demonstrate that the leaf extracts of C. infundibuliformis presents excellent antimicrobial activities and thus have great potential as a source for natural health care products.

  18. Preliminary C3 Loading Analysis for Future High-Altitude Unmanned Aircraft in the NAS

    Science.gov (United States)

    Ho, Yan-Shek; Gheorghisor, Izabela; Box, Frank

    2006-01-01

    This document provides a preliminary assessment and summary of the command, control, and communications (C(sup 3)) loading requirements of a generic future high-altitude, long-endurance unmanned aircraft (UA) operating at in the National Airspace System. Two principal types of C(sup 3) traffic are considered in our analysis: communications links providing air traffic services (ATS) to the UA and its human pilot, and the command and control data links enabling the pilot to operate the UA remotely. we have quantified the loading requirements of both types of traffic for two different assumed levels of UA autonomy. Our results indicate that the potential use of UA-borne relays for the ATS links, and the degree of autonomy exercised by the UA during the departure and arrival phases of its flight, will be among the key drivers of C(sup 3) loading and bandwidth requirements.

  19. Visual Assessment on Coastal Cruise Tourism: A Preliminary Planning Using Importance Performance Analysis

    Science.gov (United States)

    Trisutomo, S.

    2017-07-01

    Importance-Performance Analysis (IPA) has been widely applied in many cases. In this research, IPA was applied to measure perceive on coastal tourism objects and its possibility to be developed as coastal cruise tourism in Makassar. Three objects, i.e. Akkarena recreational site, Losari public space at waterfront, and Paotere traditional Phinisi ships port, were selected and assessed visually from water area by a group of purposive resource persons. The importance and performance of 10 attributes of each site were scored using Likert scale from 1 to 5. Data were processed by SPSS-21 than resulted Cartesian graph which the scores were divided in four quadrants: Quadrant I concentric here, Quadrant II keep up the good work, Quadrant III low priority, and Quadrant IV possible overkill. The attributes in each quadrant could be considered as the platform for preliminary planning of coastal cruise tour in Makassar

  20. Preliminary control system design and analysis for the Space Station Furnace Facility thermal control system

    Science.gov (United States)

    Jackson, M. E.

    1995-01-01

    This report presents the Space Station Furnace Facility (SSFF) thermal control system (TCS) preliminary control system design and analysis. The SSFF provides the necessary core systems to operate various materials processing furnaces. The TCS is defined as one of the core systems, and its function is to collect excess heat from furnaces and to provide precise cold temperature control of components and of certain furnace zones. Physical interconnection of parallel thermal control subsystems through a common pump implies the description of the TCS by coupled nonlinear differential equations in pressure and flow. This report formulates the system equations and develops the controllers that cause the interconnected subsystems to satisfy flow rate tracking requirements. Extensive digital simulation results are presented to show the flow rate tracking performance.

  1. Acanthamoeba polyphaga mimivirus NDK: preliminary crystallographic analysis of the first viral nucleoside diphosphate kinase.

    Science.gov (United States)

    Jeudy, Sandra; Coutard, Bruno; Lebrun, Régine; Abergel, Chantal

    2005-06-01

    The complete sequence of the largest known double-stranded DNA virus, Acanthamoeba polyphaga mimivirus, has recently been determined [Raoult et al. (2004), Science, 306, 1344-1350] and revealed numerous genes not expected to be found in a virus. A comprehensive structural and functional study of these gene products was initiated [Abergel et al. (2005), Acta Cryst. F61, 212-215] both to better understand their role in the virus physiology and to obtain some clues to the origin of DNA viruses. Here, the preliminary crystallographic analysis of the viral nucleoside diphosphate kinase protein is reported. The crystal belongs to the cubic space group P2(1)3, with unit-cell parameter 99.425 A. The self-rotation function confirms that there are two monomers per asymmetric unit related by a twofold non-crystallographic axis and that the unit cell thus contains four biological entities.

  2. Preliminary analysis of habitat utilization by woodland caribou in northwestern Ontario using satellite telemetry

    Directory of Open Access Journals (Sweden)

    T.L. Hillis

    1998-03-01

    Full Text Available Locational data collected over a one year period from 10 female woodland caribou, Rangifer tarandus caribou, collared with Argos satellite collars in northwestern Ontario, Canada were superimposed on supervised Landsat images using Geographical Information System (GIS technology. Landscape parameters, land cover classifications, and drainage were utilized to create the basemap. Using ARCVIEW software, all digital fixes from collared caribou with information of date, time, and activity status were overlain on the basemap to facilitate a preliminary analysis of habitat use in this species. Results supported the conclusions (1 that woodland caribou in northwestern Ontario select habitats containing high to moderate conifer cover and avoided disturbed areas and shrub-rich habitats, (2 that seasonal changes in habitat utilization occurs in females of this species, and (3 that satellite telemetry technology can be employed in the boreal forest ecosystem to assess habitat utilization by large ungulate species.

  3. Crystallization and preliminary X-ray analysis of Leishmania major glyoxalase I

    Energy Technology Data Exchange (ETDEWEB)

    Ariza, Antonio; Vickers, Tim J.; Greig, Neil; Fairlamb, Alan H.; Bond, Charles S., E-mail: c.s.bond@dundee.ac.uk [Division of Biological Chemistry and Molecular Microbiology, Wellcome Trust Biocentre, School of Life Sciences, University of Dundee, Dundee DD1 5EH,Scotland (United Kingdom)

    2005-08-01

    The detoxification enzyme glyoxalase I from L. major has been crystallized. Preliminary molecular-replacement calculations indicate the presence of three glyoxalase I dimers in the asymmetric unit. Glyoxalase I (GLO1) is a putative drug target for trypanosomatids, which are pathogenic protozoa that include the causative agents of leishmaniasis. Significant sequence and functional differences between Leishmania major and human GLO1 suggest that it may make a suitable template for rational inhibitor design. L. major GLO1 was crystallized in two forms: the first is extremely disordered and does not diffract, while the second, an orthorhombic form, produces diffraction to 2.0 Å. Molecular-replacement calculations indicate that there are three GLO1 dimers in the asymmetric unit, which take up a helical arrangement with their molecular dyads arranged approximately perpendicular to the c axis. Further analysis of these data are under way.

  4. Cognitive Work Analysis: Preliminary Data for a Model of Problem Solving Strategies

    Science.gov (United States)

    Rothmayer, Mark; Blue, Jennifer

    2007-10-01

    Investigations into problem solving strategies are part of the field of physics education research where investigators seek to improve physics instruction by conducting basic research of problem solving abilities among students, differences in knowledge representations between experts and novices, and how to transfer knowledge structures more effectively onto novices. We developed a new conceptual research tool in our laboratory, where we could potentially map the step by step flow of problem solving strategies among experts and novices. This model is derived from the theory of Cognitive Work Analysis, which is grounded in ecological psychology, and as far as we know it has never been applied to a knowledge domain like physics. We collected survey data from 140 undergraduates enrolled in an algebra based introductory physics course at Miami University as part of a larger study aimed to test the validity of the model. Preliminary data will be presented and discussed.

  5. Preliminary risk analysis applied to the transmission of Creutzfeldt-Jakob disease.

    Science.gov (United States)

    Bertrand, E; Schlatter, J

    2011-01-01

    Transmissible spongiform encephalopathy (TSE) is a degenerative disease of the central nervous system. As yet, there is no human screening test and no effective treatment. This disease is invariably fatal. General preventive measures are therefore essential. The objective of this study is to analyze and address on a prioritized basis the risks relating to the transmission of Creutzfeldt-Jakob disease during surgical operations by means of a preliminary risk analysis (PRA). The PRA produces 63 scenarios with maximum risk relating to operational and legal dangers. The study recommends a number of courses of action, such as training and internal controls, in order to reduce the risks identified. A procedure has been drawn up and assessed for each action. This PRA makes it possible to target and significantly reduce the potential dangers for transmission of Creutzfeldt-Jakob disease through the use of medical instruments.

  6. Purification, crystallization and preliminary X-ray analysis of uridine phosphorylase from Salmonella typhimurium.

    Science.gov (United States)

    Dontsova, Mariya V; Savochkina, Yulia A; Gabdoulkhakov, Azat G; Baidakov, Sergey N; Lyashenko, Andrey V; Zolotukhina, Maria; Errais Lopes, Liubov; Garber, Mariya B; Morgunova, Ekaterina Yu; Nikonov, Stanislav V; Mironov, Alexandr S; Ealick, Steven E; Mikhailov, Al 'Bert M

    2004-04-01

    The structural udp gene encoding uridine phosphorylase (UPh) was cloned from the Salmonella typhimurium chromosome and overexpressed in Escherichia coli cells. S. typhimurium UPh (StUPh) was purified to apparent homogeneity and crystallized. The primary structure of StUPh has high homology to the UPh from E. coli, but the enzymes differ substantially in substrate specificity and sensitivity to the polarity of the medium. Single crystals of StUPh were grown using hanging-drop vapor diffusion with PEG 8000 as the precipitant. X-ray diffraction data were collected to 2.9 A resolution. Preliminary analysis of the diffraction data indicated that the crystal belonged to space group P6(1(5)), with unit-cell parameters a = 92.3, c = 267.5 A. The solvent content is 37.7% assuming the presence of one StUPh hexamer per asymmetric unit.

  7. Preliminary performance analysis of the advanced pulse compression noise radar waveform

    Science.gov (United States)

    Govoni, Mark A.; Moyer, Lee R.

    2012-06-01

    Noise radar systems encounter target fluctuation behavior similar to that of conventional systems. For noise radar systems, however, the fluctuations are not only dictated by target composition and geometry, but also by the non-uniform power envelope of their random transmit signals. This third dependency is of interest and serves as the basis for the preliminary analysis conducted in this manuscript. General conclusions are drawn on the implications of having a random power envelope and the impacts it could have on both the transmit and receive processes. Using an advanced pulse compression noise (APCN) radar waveform as the constituent signal, a computer simulation aids in quantifying potential losses and the impacts they might have on the detection performance of a real radar system.

  8. Global stability analysis on a class of cellular neural networks

    Institute of Scientific and Technical Information of China (English)

    ZHANG; Yi

    2001-01-01

    [1]Chua, L. O., Yang, L., Cellular neural networks: Theory, IEEE Trans. CAS, 1988, (10): 1257.[2]Chua, L. O., Yang, L., Cellular neural networks: Applications, IEEE Trans. CAS, 1988, (10): 1273.[3]Chua, L. O., Roska, T., The CNN paradigm, IEEE Trans. CAS-I, 1993, (3): 147.[4]Matsumoto, T. Chua, L. O., Suzuki, H., CNN cloning template: Connected component detector, IEEE Trans. CAS, 1990, (8): 633.[5]Cao, L, Sun, Y, Yu, J., A CNN-based signature verification system,Proc. ICONIP′95, Beijing, 1995, 913—916.[6]Roska, T., Chua, L. O., The CNN universal machine: An analogic array computer, IEEE Trans. CAS Ⅱ, 1993, (3): 163.[7]Chua, L. O., Roska, T., Stability of a class of nonreciprocal cellular neural networks, IEEE Trans. CAS, 1990, (3): 1520.[8]Roska, T., Wu, C. W., Balsi, M. Et al., Stability and dynamics of delay type general and cellular neural networks, IEEE Trans. CAS, 1992, (6): 487.[9]Roska, T., Wu, C. W., Chua, L. O., Stability of cellular neural networks with dominant nonlinear and delaytype templates, IEEE Trans. CAS, 1993, (4): 270.[10]Civalleri, P. P., On stability of cellular neural networks with delay, IEEE Trans. CAS-I, 1993, (3): 157.[11]Gilli, G., Stability of cellular neural network and delayed cellular neural networks with nonpositive templates and nonmonotonic output functions, IEEE Trans CAS-I, 1994, (8): 518.[12]Baldi, P., Atiya, A. F., How delays affect neural dynamics and learning, IEEE Trans. On Neural Networks, 1994, (4): 612.[13]Liao, X. X., Mathematic foundation of cellular neural networks (Ⅰ), Science in China, Ser. A, 1994, 37(9): 902.[14]Liao, X. X., Mathematic foundation of cellular neural networks (Ⅱ), Science in China, Ser. A, 1994, 37(9): 1037.[15]Zhang, Y., Global exponential stability and periodic solutions of delay Hopfild neural networks, International J. Sys. Sci., 1996, (2): 227.[16]Zhang Yi, Zhong, S. M., Li, Z. L., Periodic solutions and global

  9. Preliminary Analysis of Aircraft Loss of Control Accidents: Worst Case Precursor Combinations and Temporal Sequencing

    Science.gov (United States)

    Belcastro, Christine M.; Groff, Loren; Newman, Richard L.; Foster, John V.; Crider, Dennis H.; Klyde, David H.; Huston, A. McCall

    2014-01-01

    Aircraft loss of control (LOC) is a leading cause of fatal accidents across all transport airplane and operational classes, and can result from a wide spectrum of hazards, often occurring in combination. Technologies developed for LOC prevention and recovery must therefore be effective under a wide variety of conditions and uncertainties, including multiple hazards, and their validation must provide a means of assessing system effectiveness and coverage of these hazards. This requires the definition of a comprehensive set of LOC test scenarios based on accident and incident data as well as future risks. This paper defines a comprehensive set of accidents and incidents over a recent 15 year period, and presents preliminary analysis results to identify worst-case combinations of causal and contributing factors (i.e., accident precursors) and how they sequence in time. Such analyses can provide insight in developing effective solutions for LOC, and form the basis for developing test scenarios that can be used in evaluating them. Preliminary findings based on the results of this paper indicate that system failures or malfunctions, crew actions or inactions, vehicle impairment conditions, and vehicle upsets contributed the most to accidents and fatalities, followed by inclement weather or atmospheric disturbances and poor visibility. Follow-on research will include finalizing the analysis through a team consensus process, defining future risks, and developing a comprehensive set of test scenarios with correlation to the accidents, incidents, and future risks. Since enhanced engineering simulations are required for batch and piloted evaluations under realistic LOC precursor conditions, these test scenarios can also serve as a high-level requirement for defining the engineering simulation enhancements needed for generating them.

  10. Global analysis of viral infection in an archaeal model system

    Directory of Open Access Journals (Sweden)

    Walid S. Maaty

    2012-12-01

    Full Text Available The origin and evolutionary relationship of viruses is poorly understood. This makes archaeal virus-host of particular interest because the hosts generally root near the base of phylogenetic trees, while some of the viruses have clear structural similarities to those that infect prokaryotic and eukaryotic cells. Despite the advantageous position for use in evolutionary studies, little is known about archaeal viruses or how they interact with their hosts, compared to viruses of bacteria and eukaryotes. In addition, many archaeal viruses have been isolated from extreme environments and present a unique opportunity for elucidating factors that are important for existence at the extremes.. In this article we focus on virus-host interactions using a proteomics approach to study Sulfolobus Turreted Icosahedral Virus (STIV infection of Sulfolobus solfataricus P2. Using cultures grown from the ATCC cell stock, a single cycle of STIV infection was sampled 6 times over a 72 hr period. More than 700 proteins were identified throughout the course of the experiments. Seventy one host proteins were found to change by nearly two-fold (p<0.05 with 40 becoming more abundant and 31 less abundant. The modulated proteins represent 30 different cell pathways and 14 COG groups. 2D gel analysis showed that changes in post translational modifications were a common feature of the affected proteins. The results from these studies showed that the prokaryotic antiviral adaptive immune system CRISPR associated proteins (CAS proteins were regulated in response to the virus infection. It was found that regulated proteins come from mRNAs with a shorter than average half-life. In addition, activity-based protein profiling (ABPP profiling on 2D gels showed caspase, hydrolase and tyrosine phosphatase enzyme activity labeling at the protein isoform level. Together, this data provides a more detailed global view of archaeal cellular responses to viral infection, demonstrates the

  11. Atom-by-atom analysis of global downhill protein folding

    Science.gov (United States)

    Sadqi, Mourad; Fushman, David; Muñoz, Victor

    2006-07-01

    Protein folding is an inherently complex process involving coordination of the intricate networks of weak interactions that stabilize native three-dimensional structures. In the conventional paradigm, simple protein structures are assumed to fold in an all-or-none process that is inaccessible to experiment. Existing experimental methods therefore probe folding mechanisms indirectly. A widely used approach interprets changes in protein stability and/or folding kinetics, induced by engineered mutations, in terms of the structure of the native protein. In addition to limitations in connecting energetics with structure, mutational methods have significant experimental uncertainties and are unable to map complex networks of interactions. In contrast, analytical theory predicts small barriers to folding and the possibility of downhill folding. These theoretical predictions have been confirmed experimentally in recent years, including the observation of global downhill folding. However, a key remaining question is whether downhill folding can indeed lead to the high-resolution analysis of protein folding processes. Here we show, with the use of nuclear magnetic resonance (NMR), that the downhill protein BBL from Escherichia coli unfolds atom by atom starting from a defined three-dimensional structure. Thermal unfolding data on 158 backbone and side-chain protons out of a total of 204 provide a detailed view of the structural events during folding. This view confirms the statistical nature of folding, and exposes the interplay between hydrogen bonding, hydrophobic forces, backbone conformation and side-chain entropy. From the data we also obtain a map of the interaction network in this protein, which reveals the source of folding cooperativity. Our approach can be extended to other proteins with marginal barriers (less than 3RT), providing a new tool for the study of protein folding.

  12. Analysis of Improvement on Human Resource Management within Chinese Enterprises in Economic Globalization

    Directory of Open Access Journals (Sweden)

    Lihui Xie

    2013-04-01

    Full Text Available In this study, we analysis of improvement on human resource management within Chinese enterprises in economic globalization. China’s entry into WTO has accelerated the economic globalization pace of Chinese enterprises and Chinese economy is further integrated with the global economy in a global scope. Human resource is what economic globalization of Chinese enterprises relies on, the first resource for China to participate in the international competition and is also the key to make effective use of other resources. Nevertheless, under the background of economic globalization, human resource management in Chinese enterprises is still faced up with quite a lot of challenges and problems. In order to establish a human resource management concept of globalization and set up a human resource management mechanism to respond to the economic globalization, this study makes a discussion and proposes management method and improvement measures for reference.

  13. CAGE Analysis of China’s Trade Globalization

    Directory of Open Access Journals (Sweden)

    Emmanuel Olusegun STOBER

    2014-06-01

    Full Text Available Gravity model of international trade states that trade interaction between two countries is in direct proportion to their size measured by Gross Domestic Product and in inverse proportion to the geographic distance. Conley and Ligon (2001 argued that the relevant economic distance between countries is often not the geographic distance. Thus, this study uses original datasets on economic distance to structure observed variations, to decompose the multidimensional CAGE distance framework of globalization derived from the Newton’s Law of gravitation as it applies to China’s international interaction, to evaluate bilateral trade patterns in identifying and prioritizing the importance of cross-border flows and differences that accounted for the development of China’s global strategies. This study confirms that distance must be accounted for in the decision making of any country’s globalization process or any firm’s global expansion as the effects on cross-border economic activities are enormous.

  14. Globalization and health: a framework for analysis and action.

    Science.gov (United States)

    Woodward, D.; Drager, N.; Beaglehole, R.; Lipson, D.

    2001-01-01

    Globalization is a key challenge to public health, especially in developing countries, but the linkages between globalization and health are complex. Although a growing amount of literature has appeared on the subject, it is piecemeal, and suffers from a lack of an agreed framework for assessing the direct and indirect health effects of different aspects of globalization. This paper presents a conceptual framework for the linkages between economic globalization and health, with the intention that it will serve as a basis for synthesizing existing relevant literature, identifying gaps in knowledge, and ultimately developing national and international policies more favourable to health. The framework encompasses both the indirect effects on health, operating through the national economy, household economies and health-related sectors such as water, sanitation and education, as well as more direct effects on population-level and individual risk factors for health and on the health care system. Proposed also is a set of broad objectives for a programme of action to optimize the health effects of economic globalization. The paper concludes by identifying priorities for research corresponding with the five linkages identified as critical to the effects of globalization on health. PMID:11584737

  15. The credibility challenge for global fluvial flood risk analysis

    Science.gov (United States)

    Trigg, M. A.; Birch, C. E.; Neal, J. C.; Bates, P. D.; Smith, A.; Sampson, C. C.; Yamazaki, D.; Hirabayashi, Y.; Pappenberger, F.; Dutra, E.; Ward, P. J.; Winsemius, H. C.; Salamon, P.; Dottori, F.; Rudari, R.; Kappes, M. S.; Simpson, A. L.; Hadzilacos, G.; Fewtrell, T. J.

    2016-09-01

    Quantifying flood hazard is an essential component of resilience planning, emergency response, and mitigation, including insurance. Traditionally undertaken at catchment and national scales, recently, efforts have intensified to estimate flood risk globally to better allow consistent and equitable decision making. Global flood hazard models are now a practical reality, thanks to improvements in numerical algorithms, global datasets, computing power, and coupled modelling frameworks. Outputs of these models are vital for consistent quantification of global flood risk and in projecting the impacts of climate change. However, the urgency of these tasks means that outputs are being used as soon as they are made available and before such methods have been adequately tested. To address this, we compare multi-probability flood hazard maps for Africa from six global models and show wide variation in their flood hazard, economic loss and exposed population estimates, which has serious implications for model credibility. While there is around 30%-40% agreement in flood extent, our results show that even at continental scales, there are significant differences in hazard magnitude and spatial pattern between models, notably in deltas, arid/semi-arid zones and wetlands. This study is an important step towards a better understanding of modelling global flood hazard, which is urgently required for both current risk and climate change projections.

  16. Global analysis of heat shock response in Desulfovibrio vulgaris Hildenborough.

    Energy Technology Data Exchange (ETDEWEB)

    Arkin, A. P. (Physical Biosciences Division, Berkeley, CA); Wall, J. D. (University of Missouri-Columbia, Columbia, MO); Hazen, T. C. (Physical Biosciences Division, Berkeley, CA); He, Z. (Oak Ridge National Laboratory, Oak Ridge, TN); Zhou, J. (Oak Ridge National Laboratory, Oak Ridge, TN); Huang, K. H. (Physical Biosciences Division, Berkeley, CA); Gaucher, Sara P.; He, Q. (Oak Ridge National Laboratory, Oak Ridge, TN); Hadi, Masood Z.; Chhabra, Swapnil R.; Alm, Eric J. (Physical Biosciences Division, Berkeley, CA); Singh, A. K.

    2005-08-01

    Desulfovibrio vulgaris Hildenborough belongs to a class of sulfate-reducing bacteria (SRB) and is found ubiquitously in nature. Given the importance of SRB-mediated reduction for bioremediation of metal ion contaminants, ongoing research on D. vulgaris has been in the direction of elucidating regulatory mechanisms for this organism under a variety of stress conditions. This work presents a global view of this organism's response to elevated growth temperature using whole-cell transcriptomics and proteomics tools. Transcriptional response (1.7-fold change or greater; Z {ge} 1.5) ranged from 1,135 genes at 15 min to 1,463 genes at 120 min for a temperature up-shift of 13 C from a growth temperature of 37 C for this organism and suggested both direct and indirect modes of heat sensing. Clusters of orthologous group categories that were significantly affected included posttranslational modifications; protein turnover and chaperones (up-regulated); energy production and conversion (down-regulated), nucleotide transport, metabolism (down-regulated), and translation; ribosomal structure; and biogenesis (down-regulated). Analysis of the genome sequence revealed the presence of features of both negative and positive regulation which included the CIRCE element and promoter sequences corresponding to the alternate sigma factors {sigma}{sup 32} and {sigma}{sup 54}. While mechanisms of heat shock control for some genes appeared to coincide with those established for Escherichia coli and Bacillus subtilis, the presence of unique control schemes for several other genes was also evident. Analysis of protein expression levels using differential in-gel electrophoresis suggested good agreement with transcriptional profiles of several heat shock proteins, including DnaK (DVU0811), HtpG (DVU2643), HtrA (DVU1468), and AhpC (DVU2247). The proteomics study also suggested the possibility of posttranslational modifications in the chaperones DnaK, AhpC, GroES (DVU1977), and GroEL (DVU

  17. Development and Evaluation of Acceptance and Commitment Therapy Delivered by Psychologists and Non-Psychologists in an NHS Community Adult Mental Health Service: a Preliminary Analysis.

    Science.gov (United States)

    Richardson, Thomas; Bell, Lorraine; Bolderston, Helen; Clarke, Sue

    2017-05-11

    Previous studies have demonstrated that acceptance and commitment therapy (ACT) is effective for depression and may be useful for complex transdiagnostic clients. To conduct a preliminary evaluation of whether ACT is feasible and effective when delivered by psychologists and non-psychologists for complex clients in a National Health Service (NHS) community mental health service for adults. Staff were trained in ACT and conducted one-to-one therapy with clients. Measures on general mental health, depression, fusion and values were given pre-therapy, post-therapy and at 3-month follow-up. Standardized measures showed significant improvements post-therapy for global mental health, depression, cognitive fusion and values post-treatment. These were partially maintained at follow-up and remained after an intent-to-treat analysis. There were no differences in outcomes between psychologists and non-psychologists. ACT may be delivered effectively with limited training for complex cases in secondary care, though further research is needed.

  18. Preliminary Safety Analysis Report for the Transuranic Storage Area Retrieval Enclosure at the Idaho National Engineering Laboratory. Revision 8

    Energy Technology Data Exchange (ETDEWEB)

    1993-03-01

    This Transuranic Storage Area Retrieval Enclosure Preliminary Safety Analysis Report was completed as required by DOE Order 5480.23. The purpose of this document is to construct a safety basis that supports the design and permits construction of the facility. The facility has been designed to the requirements of a Radioactive Solid Waste Facility presented in DOE Order 6430.1A.

  19. Yucca Mountain transportation routes: Preliminary characterization and risk analysis; Volume 2, Figures [and] Volume 3, Technical Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Souleyrette, R.R. II; Sathisan, S.K.; di Bartolo, R. [Nevada Univ., Las Vegas, NV (United States). Transportation Research Center

    1991-05-31

    This report presents appendices related to the preliminary assessment and risk analysis for high-level radioactive waste transportation routes to the proposed Yucca Mountain Project repository. Information includes data on population density, traffic volume, ecologically sensitive areas, and accident history.

  20. Yucca Mountain transportation routes: Preliminary characterization and risk analysis; Volume 2, Figures [and] Volume 3, Technical Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Souleyrette, R.R. II; Sathisan, S.K.; di Bartolo, R. [Nevada Univ., Las Vegas, NV (United States). Transportation Research Center

    1991-05-31

    This report presents appendices related to the preliminary assessment and risk analysis for high-level radioactive waste transportation routes to the proposed Yucca Mountain Project repository. Information includes data on population density, traffic volume, ecologically sensitive areas, and accident history.

  1. Waste Feed Delivery System Phase 1 Preliminary Reliability and Availability and Maintainability Analysis [SEC 1 and 2

    Energy Technology Data Exchange (ETDEWEB)

    CARLSON, A.B.

    1999-11-11

    The document presents updated results of the preliminary reliability, availability, maintainability analysis performed for delivery of waste feed from tanks 241-AZ-101 and 241-AN-105 to British Nuclear Fuels Limited, inc. under the Tank Waste Remediation System Privatization Contract. The operational schedule delay risk is estimated and contributing factors are discussed.

  2. A preliminary assessment of using a white light confocal imaging profiler for cut mark analysis.

    Science.gov (United States)

    Schmidt, Christopher W; Moore, Christopher R; Leifheit, Randell

    2012-01-01

    White light confocal microscopy creates detailed 3D representations of microsurfaces that can be qualitatively and quantitatively analyzed. The study describes its application to the analysis of cut marks on bone, particularly when discerning cuts made by steel tools from those made by stone. The process described comes from a study where cuts were manually made on a cow rib with seven cutting tools, four stone (an unmodified chert flake, a chert biface, a bifacially ground slate fragment, and an unsharpened piece of slate), and three steel (a Swiss Army Knife, a serrate steak knife, and a serrate saw). Kerfs were magnified ×20 and 3D data clouds were generated using a Sensofar(®) White Light Confocal Profiler (WLCP). Kerf profiles and surface areas, volumes, mean depths, and maximum depths were calculated with proprietary software (SensoScan(®) and SolarMap(®)). For the most part, the stone tools make shallower and wider cuts. Kerf floors can be studied at higher magnifications; they were viewed at ×100. When comparing the kerf floors of the unsharpened slate and the serrate steak knife it was found that the slate floor was more uneven, but the serrate steak knife generated more overall relief. Although preliminary, the approach described here successfully distinguishes stone and steel tools; the authors conclude that the WLCP is a promising technology for cut mark analysis because of the very detailed 3D representations it creates and the numerous avenues of analysis it provides.

  3. Preliminary Drop Time Analysis of a Control Rod Using CFD Code

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Myoung Hwan; Park, Jin Seok; Lee, Won Jae [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Park, Jun Hong [SEST Co., Seoul (Korea, Republic of)

    2010-05-15

    A control rod drive mechanism (CRDM) is a reactor regulating system, which can insert and withdraw a control rod containing a neutron absorbing material to control the reactivity of the reactor core. The latch type CRDM for the SMART (System-integrated Modular Advanced ReacTor) is going to be used. The drop time of the control rod in the design stage is one of important parameters for a safety analysis of the reactor. When the control rod is falling down into the core, it is retarded by various forces acting on it such as fluid resistance buoyancy and mechanical friction caused by contacting the inner surface of the guide thimble, etc.. However, complicated coupling of the various forces makes it difficult to predict the drop behavior. This paper describes the development of the 3D CFD analysis model using a FLUENT code. The single control rod of the Westinghouse 17x17 type optimized fuel assembly (W-OFA) was considered for the verification of the CFD model. A preliminary drop time analysis for the SMART with the simulated control rod was performed

  4. Facilitation of the PED analysis of large molecules by using global coordinates.

    Science.gov (United States)

    Jamróz, Michał H; Ostrowski, Sławomir; Dobrowolski, Jan Cz

    2015-10-01

    Global coordinates have been found to be useful in the potential energy distribution (PED) analyses of the following large molecules: [13]-acene and [33]-helicene. The global coordinate is defined based on much distanced fragments of the analysed molecule, whereas so far, the coordinates used in the analysis were based on stretchings, bendings, or torsions of the adjacent atoms. It has been shown that the PED analyses performed using the global coordinate and the classical ones can lead to exactly the same PED contributions. The global coordinates may significantly improve the facility of the analysis of the vibrational spectra of large molecules.

  5. Automated analysis of whole skeletal muscle for muscular atrophy detection of ALS in whole-body CT images: preliminary study

    Science.gov (United States)

    Kamiya, Naoki; Ieda, Kosuke; Zhou, Xiangrong; Yamada, Megumi; Kato, Hiroki; Muramatsu, Chisako; Hara, Takeshi; Miyoshi, Toshiharu; Inuzuka, Takashi; Matsuo, Masayuki; Fujita, Hiroshi

    2017-03-01

    Amyotrophic lateral sclerosis (ALS) causes functional disorders such as difficulty in breathing and swallowing through the atrophy of voluntary muscles. ALS in its early stages is difficult to diagnose because of the difficulty in differentiating it from other muscular diseases. In addition, image inspection methods for aggressive diagnosis for ALS have not yet been established. The purpose of this study is to develop an automatic analysis system of the whole skeletal muscle to support the early differential diagnosis of ALS using whole-body CT images. In this study, the muscular atrophy parts including ALS patients are automatically identified by recognizing and segmenting whole skeletal muscle in the preliminary steps. First, the skeleton is identified by its gray value information. Second, the initial area of the body cavity is recognized by the deformation of the thoracic cavity based on the anatomical segmented skeleton. Third, the abdominal cavity boundary is recognized using ABM for precisely recognizing the body cavity. The body cavity is precisely recognized by non-rigid registration method based on the reference points of the abdominal cavity boundary. Fourth, the whole skeletal muscle is recognized by excluding the skeleton, the body cavity, and the subcutaneous fat. Additionally, the areas of muscular atrophy including ALS patients are automatically identified by comparison of the muscle mass. The experiments were carried out for ten cases with abnormality in the skeletal muscle. Global recognition and segmentation of the whole skeletal muscle were well realized in eight cases. Moreover, the areas of muscular atrophy including ALS patients were well identified in the lower limbs. As a result, this study indicated the basic technology to detect the muscle atrophy including ALS. In the future, it will be necessary to consider methods to differentiate other kinds of muscular atrophy as well as the clinical application of this detection method for early ALS

  6. Analysis of Current Global Nuclear Safety and Security Cooperation

    Institute of Scientific and Technical Information of China (English)

    Liu; Chong

    2014-01-01

    Last year, global nuclear security and safety cooperation achieved some progress. In terms of nuclear safety, too many flaws are exposed by the current severe situation of the Fukushima in Japan’s new nuclear safety regulation system, and sound the alarm for East Asia countries accelerating the regional nuclear safety cooperation. In terms of nuclear security, since the Seoul Summit in March 2012, global nuclear security cooperation has achieved new successes. IAEA has and would play the central role in pushing forward the international framework and strengthening nuclear security globally. However, there are still some obstacles to overcome in the future, which need international society to enhance communication and common understanding, especially high-level consultations.

  7. Global comparative transcriptome analysis of cartilage formation in vivo

    Directory of Open Access Journals (Sweden)

    Brachvogel Bent

    2009-03-01

    family members. Conclusion These data represent the first global gene expression profiling analysis of chondrogenic tissues during in vivo development. They identify genes for further study on their functional roles in chondrogenesis, and provide a comprehensive and important resource for future studies on cartilage development and disease.

  8. Methodological considerations for global analysis of cellular FLIM/FRET measurements

    Science.gov (United States)

    Adbul Rahim, Nur Aida; Pelet, Serge; Kamm, Roger D.; So, Peter T. C.

    2012-02-01

    Global algorithms can improve the analysis of fluorescence energy transfer (FRET) measurement based on fluorescence lifetime microscopy. However, global analysis of FRET data is also susceptible to experimental artifacts. This work examines several common artifacts and suggests remedial experimental protocols. Specifically, we examined the accuracy of different methods for instrument response extraction and propose an adaptive method based on the mean lifetime of fluorescent proteins. We further examined the effects of image segmentation and a priori constraints on the accuracy of lifetime extraction. Methods to test the applicability of global analysis on cellular data are proposed and demonstrated. The accuracy of global fitting degrades with lower photon count. By systematically tracking the effect of the minimum photon count on lifetime and FRET prefactors when carrying out global analysis, we demonstrate a correction procedure to recover the correct FRET parameters, allowing us to obtain protein interaction information even in dim cellular regions with photon counts as low as 100 per decay curve.

  9. Bridging the gaps for global sustainable development: a quantitative analysis.

    Science.gov (United States)

    Udo, Victor E; Jansson, Peter Mark

    2009-09-01

    Global human progress occurs in a complex web of interactions between society, technology and the environment as driven by governance and infrastructure management capacity among nations. In our globalizing world, this complex web of interactions over the last 200 years has resulted in the chronic widening of economic and political gaps between the haves and the have-nots with consequential global cultural and ecosystem challenges. At the bottom of these challenges is the issue of resource limitations on our finite planet with increasing population. The problem is further compounded by pleasure-driven and poverty-driven ecological depletion and pollution by the haves and the have-nots respectively. These challenges are explored in this paper as global sustainable development (SD) quantitatively; in order to assess the gaps that need to be bridged. Although there has been significant rhetoric on SD with very many qualitative definitions offered, very few quantitative definitions of SD exist. The few that do exist tend to measure SD in terms of social, energy, economic and environmental dimensions. In our research, we used several human survival, development, and progress variables to create an aggregate SD parameter that describes the capacity of nations in three dimensions: social sustainability, environmental sustainability and technological sustainability. Using our proposed quantitative definition of SD and data from relatively reputable secondary sources, 132 nations were ranked and compared. Our comparisons indicate a global hierarchy of needs among nations similar to Maslow's at the individual level. As in Maslow's hierarchy of needs, nations that are struggling to survive are less concerned with environmental sustainability than advanced and stable nations. Nations such as the United States, Canada, Finland, Norway and others have higher SD capacity, and thus, are higher on their hierarchy of needs than nations such as Nigeria, Vietnam, Mexico and other

  10. OTC Derivatives and Global Economic Activity: An Empirical Analysis

    Directory of Open Access Journals (Sweden)

    Gordon Bodnar

    2017-06-01

    Full Text Available That the global market for derivatives has expanded beyond recognition is well known. What is not know is how this market interacts with economic activity. We provide the first empirical characterization of interdependencies between OECD economic activity and the global OTC derivatives market. To this end, we apply a vector-error correction model to OTC derivatives disaggregated across instruments and counterparties. The results indicate that with one exception, the heterogeneity of OTC contracts is too pronounced to be reliably summarized by our measures of economic activity. The one exception is interest-rate derivatives held by Other Financial Institutions.

  11. Global annealing genetic algorithm and its convergence analysis

    Institute of Scientific and Technical Information of China (English)

    张讲社; 徐宗本; 梁怡

    1997-01-01

    A new selection mechanism termed global annealing selection (GAnS) is proposed for the genetic algorithm. It is proved that the GAnS genetic algorithm converges to the global optimums if and only if the parents are allowed to compete for reproduction, and that the variance of population’s fitness can be used as a natural stopping criterion. Numerical simulations show that the new algorithm has stronger ability to escape from local maximum and converges more rapidly than canonical genetic algorithm.

  12. A preliminary analysis of climate change effect on long-term risk-based design of flood defense

    Science.gov (United States)

    Wang, L.; Van Gelder, P. H. A. J. M.; Vrijling, J. K.

    2012-04-01

    The lifetime of a flood defense usually lasts for decades or centuries. The future flood probabilistic distribution is not stationary due to climate change. Therefore in the long-term design of flood defense systems, the effect of climate change should be taken into account. The design height of Bengbu dike segment (about 10 km) along Huai River in China is studied as an example to explore the potential effects of climate change on long-term risk-based design. The economic-optimal design height of the dike is determined based on cost-benefit analysis. In this analysis the incremental investments in more safety are balanced with the reduction of the risk. Since climate change will result in the change of flood probability and hence the change of flooding risk, the optimal height might be shifted. To describe the possible future climate, the ensemble prediction of Global Climate Models (GCMs) is used in the study. River runoff series, which is required in deriving annual probability of peak runoff, is obtained by forcing a hydrological model with each GCM climate prediction. Then the probability of high water level in the river is derived based on the relationship between water level and peak runoff. The probability of flooding is assumed to equal to the exceedance probability of the high water level in the river. The possible future flood risk is calculated based on the flooding probability estimates, and is corresponding to each member of the GCMs ensemble. The result will provide information about the significance of potential effects of climate change on the long-term design of flood defense. With comparison to the baseline period, the shift of risk curve in future will be shown on the cost-benefit diagram as well as the change of economic optimal design dike height. As it is a preliminary analysis in this study a sensitivity analysis will be carried out. The sensitivity of use of GCMs ensemble, the damage value and the investment cost will be investigated.

  13. Climate Prediction Center (CPC) Global Land Surface Air Temperature Analysis

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A station observation-based global land monthly mean surface air temperature dataset at 0.5 x 0.5 latitude-longitude resolution for the period from 1948 to the...

  14. Climate Prediction Center (CPC) Global Land Surface Air Temperature Analysis

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A station observation-based global land monthly mean surface air temperature dataset at 0.5 0.5 latitude-longitude resolution for the period from 1948 to the present...

  15. Effective field theory of dark matter: a global analysis

    NARCIS (Netherlands)

    Liem, S.; Bertone, G.; Calore, F.; Ruiz de Austri, R.; Tait, T.M.P.; Trotta, R.; Weniger, C.

    2016-01-01

    We present global fits of an effective field theory description of real, and complex scalar dark matter candidates. We simultaneously take into account all possible dimension 6 operators consisting of dark matter bilinears and gauge invariant combinations of quark and gluon fields. We derive constra

  16. Maximum-entropy clustering algorithm and its global convergence analysis

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Constructing a batch of differentiable entropy functions touniformly approximate an objective function by means of the maximum-entropy principle, a new clustering algorithm, called maximum-entropy clustering algorithm, is proposed based on optimization theory. This algorithm is a soft generalization of the hard C-means algorithm and possesses global convergence. Its relations with other clustering algorithms are discussed.

  17. Characterization and global analysis of a family of Poisson structures

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez-Bermejo, Benito [Escuela Superior de Ciencias Experimentales y Tecnologia, Edificio Departamental II, Universidad Rey Juan Carlos, Calle Tulipan S/N, 28933 (Mostoles), Madrid (Spain)]. E-mail: benito.hernandez@urjc.es

    2006-06-26

    A three-dimensional family of solutions of the Jacobi equations for Poisson systems is characterized. In spite of its general form it is possible the explicit and global determination of its main features, such as the symplectic structure and the construction of the Darboux canonical form. Examples are given.

  18. Preliminary analysis of Stearoyl Co-A Desaturase gene transcripts in River buffalo

    Directory of Open Access Journals (Sweden)

    L. Ramunno

    2010-02-01

    Full Text Available Stearoyl-CoA desaturase (SCD is a key enzyme in the biosynthesis of monounsaturated fatty acids (MUFAs. In cattle, SCD gene extends over a DNA segment of ~17.0 Kb, and it is organized in 6 exons and 5 introns. The SCD gene has been indicated as the candidate gene to change the saturated/unsaturated FAs ratio and hence it has been suggested as the gene influencing the fat quality. In cattle, eight SNPs have been identified and one of them, (T→C at 231st nt of 5th exon, is responsible for the Val→Ala amino acid change. The C allele has been associated with higher content of MUFAs in carcasses, and it is positively related to a higher index of desaturation (C18:0/C18:1 and C16:0/C16:1 in the milk. In this study, we report on preliminary results of analysis of transcripts of the SCD encoding gene in river buffalo. The electrophoretic analysis of the RT-PCR products and the subsequent sequencing showed at least five different populations of mRNA. The most represented population is correctly assembled (~1300 bp, followed by the one which is deleted of ~750bp, corresponding to the 3rd, 4th and 5th exon and partially to the 2nd and 6th exon.

  19. Biomarkers of Eating Disorders Using Support Vector Machine Analysis of Structural Neuroimaging Data: Preliminary Results.

    Science.gov (United States)

    Cerasa, Antonio; Castiglioni, Isabella; Salvatore, Christian; Funaro, Angela; Martino, Iolanda; Alfano, Stefania; Donzuso, Giulia; Perrotta, Paolo; Gioia, Maria Cecilia; Gilardi, Maria Carla; Quattrone, Aldo

    2015-01-01

    Presently, there are no valid biomarkers to identify individuals with eating disorders (ED). The aim of this work was to assess the feasibility of a machine learning method for extracting reliable neuroimaging features allowing individual categorization of patients with ED. Support Vector Machine (SVM) technique, combined with a pattern recognition method, was employed utilizing structural magnetic resonance images. Seventeen females with ED (six with diagnosis of anorexia nervosa and 11 with bulimia nervosa) were compared against 17 body mass index-matched healthy controls (HC). Machine learning allowed individual diagnosis of ED versus HC with an Accuracy ≥ 0.80. Voxel-based pattern recognition analysis demonstrated that voxels influencing the classification Accuracy involved the occipital cortex, the posterior cerebellar lobule, precuneus, sensorimotor/premotor cortices, and the medial prefrontal cortex, all critical regions known to be strongly involved in the pathophysiological mechanisms of ED. Although these findings should be considered preliminary given the small size investigated, SVM analysis highlights the role of well-known brain regions as possible biomarkers to distinguish ED from HC at an individual level, thus encouraging the translational implementation of this new multivariate approach in the clinical practice.

  20. Biomarkers of Eating Disorders Using Support Vector Machine Analysis of Structural Neuroimaging Data: Preliminary Results

    Directory of Open Access Journals (Sweden)

    Antonio Cerasa

    2015-01-01

    Full Text Available Presently, there are no valid biomarkers to identify individuals with eating disorders (ED. The aim of this work was to assess the feasibility of a machine learning method for extracting reliable neuroimaging features allowing individual categorization of patients with ED. Support Vector Machine (SVM technique, combined with a pattern recognition method, was employed utilizing structural magnetic resonance images. Seventeen females with ED (six with diagnosis of anorexia nervosa and 11 with bulimia nervosa were compared against 17 body mass index-matched healthy controls (HC. Machine learning allowed individual diagnosis of ED versus HC with an Accuracy ≥ 0.80. Voxel-based pattern recognition analysis demonstrated that voxels influencing the classification Accuracy involved the occipital cortex, the posterior cerebellar lobule, precuneus, sensorimotor/premotor cortices, and the medial prefrontal cortex, all critical regions known to be strongly involved in the pathophysiological mechanisms of ED. Although these findings should be considered preliminary given the small size investigated, SVM analysis highlights the role of well-known brain regions as possible biomarkers to distinguish ED from HC at an individual level, thus encouraging the translational implementation of this new multivariate approach in the clinical practice.

  1. The 6 April 2009 earthquake at L'Aquila: a preliminary analysis of magnetic field measurements

    Directory of Open Access Journals (Sweden)

    U. Villante

    2010-02-01

    Full Text Available Several investigations reported the possible identification of anomalous geomagnetic field signals prior to earthquake occurrence. In the ULF frequency range, candidates for precursory signatures have been proposed in the increase in the noise background and polarization parameter (i.e. the ratio between the amplitude/power of the vertical component and that one of the horizontal component, in the changing characteristics of the slope of the power spectrum and fractal dimension, in the possible occurrence of short duration pulses. We conducted, with conventional techniques of data processing, a preliminary analysis of the magnetic field observations performed at L'Aquila during three months preceding the 6 April 2009 earthquake, focusing attention on the possible occurrence of features similar to those identified in previous events. Within the limits of this analysis, we do not find compelling evidence for any of the features which have been proposed as earthquake precursors: indeed, most of aspects of our observations (which, in some cases, appear consistent with previous findings might be interpreted in terms of the general magnetospheric conditions and/or of different sources.

  2. Crystallization and preliminary X-ray diffraction analysis of human adenovirus

    Energy Technology Data Exchange (ETDEWEB)

    Reddy, V.S.; Natchiar, S.K.; Gritton, L.; Mullen, T.-M.; Stewart, P.L.; Nemerow, G.R. (Scripps); (Vanderbilt)

    2010-07-22

    Replication-defective and conditionally replicating adenovirus (AdV) vectors are currently being utilized in {approx}25% of human gene transfer clinical trials. Unfortunately, progress in vector development has been hindered by a lack of accurate structural information. Here we describe the crystallization and preliminary X-ray diffraction analysis of a HAdV5 vector that displays a short flexible fiber derived from HAdV35. Crystals of Ad35F were grown in 100 mM HEPES pH 7.0, 200 mM Ca(OAc){sub 2}, 14% PEG 550 MME, 15% glycerol in 100 mM Tris-HCl 8.5. Freshly grown crystals diffracted well to 4.5 {angstrom} resolution and weakly to 3.5 {angstrom} at synchrotron sources. HAdV crystals belong to space group P1 with unit cell parameters a = 854.03 {angstrom}, b = 855.17 {angstrom}, c = 865.24 {angstrom}, {alpha} = 119.57{sup o}, {beta} = 91.71{sup o}, {gamma} = 118.08{sup o} with a single particle in the unit cell. Self-rotation and locked-rotation function analysis allowed the determination of the particle orientation. Molecular replacement, density modification and phase-extension procedures are being employed for structure determination.

  3. Ocean thermal energy conversion cold water pipe preliminary design project. Task 2. Analysis for concept selection

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-04-01

    The successful performance of the CWP is of crucial importance to the overall OTEC system; the pipe itself is considered the most critical part of the entire operation. Because of the importance the CWP, a project for the analysis and design of CWP's was begun in the fall of 1978. The goals of this project were to study a variety of concepts for delivering cold water to an OTEC plant, to analyze and rank these concepts based on their relative cost and risk, and to develop preliminary design for those concepts which seemed most promising. Two representative platforms and sites were chosen: a spar buoy of a Gibbs and Cox design to be moored at a site off Punta Tuna, Puerto Rico, and a barge designed by APL/Johns Hopkins University, grazing about a site approximately 200 miles east of the coast of Brazil. The approach was to concentrate on the most promising concepts and on those which were either of general interest or espoused by others (e.g., steel and concrete concepts). Much of the overall attention, therefore, focused on analyzing rigid and compliant wall design, while stockade (except for the special case of the FRP stockade) and bottom-mounted concepts received less attention. A total of 67 CWP concepts were initially generated and subjected to a screening process. Of these, 16 were carried through design analysis, costing, and ranking. Study results are presented in detail. (WHK)

  4. Local/global analysis applications to ground-coupled heat transfer

    Energy Technology Data Exchange (ETDEWEB)

    Al-Anzi, Adnan [College of Engineering, Department of Architecture, Kuwait University, P.O. Box 5969, Code No. 13060, Safat (Kuwait); Krarti, Moncef [CEAE Department, CB 428, University of Colorado, 80309, Boulder, CO (United States)

    2003-09-01

    In this paper, a new local/global analysis technique is developed to solve multi-dimensional ground-coupled heat transfer problems. In particular, the novel method is applied in this paper to determine foundation heat transfer for buildings with slab-on-grade floors. It is found that analytical solutions can be used successfully to capture thermal bridging effect when integrated in the developed local/global analysis technique. In addition, it is found that significant savings in computational effort can be achieved with no sacrifice in accuracy when local/global analysis is used. (authors)

  5. Transient evolution of the global mode in turbulent swirling jets: experiments and modal stability analysis

    CERN Document Server

    Rukes, Lothar; Paschereit, Oliver; Oberleithner, Kilian

    2016-01-01

    Modal linear stability analysis has proven very successful in the analysis of coherent structures of turbulent flows. Formally, it describes the evolution of a disturbance in the limit of infinite time. In this work we apply modal linear stability analysis to a turbulent swirling jet undergoing a control parameter transient. The flow undergoes a transition from a non-vortex breakdown state to a state with a strong recirculation bubble and the associated global mode. High-speed Particle Image Velocimetry (PIV) measurements are the basis for a local linear stability analysis of the temporarily evolving base flow. This analysis reveals that the onset of the global mode is strongly linked to the formation of the internal stagnation point. Several transition scenarios are discussed and the ability of a frequency selection criterion to predict the wavemaker location, frequency and growth rate of the global mode are evaluated. We find excellent agreement between the linear global mode frequency and the experimental ...

  6. The Determination of Children's Knowledge of Global Lunar Patterns from Online Essays Using Text Mining Analysis

    Science.gov (United States)

    Cheon, Jongpil; Lee, Sangno; Smith, Walter; Song, Jaeki; Kim, Yongjin

    2013-01-01

    The purpose of this study was to use text mining analysis of early adolescents' online essays to determine their knowledge of global lunar patterns. Australian and American students in grades five to seven wrote about global lunar patterns they had discovered by sharing observations with each other via the Internet. These essays were analyzed for…

  7. The Determination of Children's Knowledge of Global Lunar Patterns from Online Essays Using Text Mining Analysis

    Science.gov (United States)

    Cheon, Jongpil; Lee, Sangno; Smith, Walter; Song, Jaeki; Kim, Yongjin

    2013-01-01

    The purpose of this study was to use text mining analysis of early adolescents' online essays to determine their knowledge of global lunar patterns. Australian and American students in grades five to seven wrote about global lunar patterns they had discovered by sharing observations with each other via the Internet. These essays were analyzed for…

  8. Risk analysis reveals global hotspots for marine debris ingestion by sea turtles

    NARCIS (Netherlands)

    Schuyler, Qamar A.; Wilcox, Chris; Townsend, Kathy A.; Wedemeyer-Strombel, Kathryn R.; Balazs, George; van Sebille, Erik; Hardesty, Britta Denise

    2016-01-01

    Plastic marine debris pollution is rapidly becoming one of the critical environmental concerns facing wildlife in the 21st century. Here we present a risk analysis for plastic ingestion by sea turtles on a global scale. We combined global marine plastic distributions based on ocean drifter data with

  9. Regional flood frequency analysis at the global scale

    Science.gov (United States)

    Smith, Andrew; Sampson, Christopher; Bates, Paul

    2015-01-01

    The characterization of flood behavior in data poor regions has been receiving considerable attention in recent years. In this context, we present the results of regional flood frequency analyses (RFFA) conducted using a global database of discharge data. A hybrid-clustering approach is used in conjunction with a flood-index methodology to provide a regionalized discharge estimates with global coverage. The procedures are implemented with varying complexity, with results indicating that catchment area and average annual rainfall explain the bulk of variability in flood frequency; a split-sample validation procedure revealed median errors in the estimation of the 100 year flood to be around 56%. However, far larger errors were also found, with performance varying between climate regions and estimation of the index-flood found to be the dominant source of uncertainty. Moreover, the RFFA procedure is utilized to provide insights on the statistical characteristics of floods across different climates and catchments.

  10. Hydropower versus irrigation—an analysis of global patterns

    Science.gov (United States)

    Zeng, Ruijie; Cai, Ximing; Ringler, Claudia; Zhu, Tingju

    2017-03-01

    Numerous reservoirs around the world provide multiple flow regulation functions; key among these are hydroelectricity production and water releases for irrigation. These functions contribute to energy and food security at national, regional and global levels. While reservoir operations for hydroelectricity production might support irrigation, there are also well-known cases where hydroelectricity production reduces water availability for irrigated food production. This study assesses these relationships at the global level using machine-learning techniques and multi-source datasets. We find that 54% of global installed hydropower capacity (around 507 thousand Megawatt) competes with irrigation. Regions where such competition exists include the Central United States, northern Europe, India, Central Asia and Oceania. On the other hand, 8% of global installed hydropower capacity (around 79 thousand Megawatt) complements irrigation, particularly in the Yellow and Yangtze River Basins of China, the East and West Coasts of the United States and most river basins of Southeast Asia, Canada and Russia. No significant relationship is found for the rest of the world. We further analyze the impact of climate variables on the relationships between hydropower and irrigation. Reservoir flood control functions that operate under increased precipitation levels appear to constrain hydroelectricity production in various river basins of the United States, South China and most basins in Europe and Oceania. On the other hand, increased reservoir evaporative losses and higher irrigation requirements due to higher potential evaporation levels may lead to increased tradeoffs between irrigation and hydropower due to reduced water availability in regions with warmer climates, such as India, South China, and the Southern United States. With most reservoirs today being built for multiple purposes, it is important for policymakers to understand and plan for growing tradeoffs between key

  11. Reactive Aggression and Suicide-Related Behaviors in Children and Adolescents: A Review and Preliminary Meta-Analysis.

    Science.gov (United States)

    Hartley, Chelsey M; Pettit, Jeremy W; Castellanos, Daniel

    2017-01-03

    The empirical literature on the association between reactive aggression and suicide-related behaviors in children and adolescents was reviewed. A narrative review of seven studies that met inclusion/exclusion criteria is followed by a preliminary meta-analysis to provide insight into the strength of the association between reactive aggression and suicide-related behaviors. Each of the seven studies reported a statistically significant association between reactive aggression and suicide-related behaviors, including suicide, nonfatal suicide attempt, and suicide ideation. Results from the meta-analysis indicated a consistent, medium-sized association (k = 7; N = 4,693; rbar = .25). The narrative review and results of the preliminary meta-analysis support the promise of pursuing future research on reactive aggression and suicide-related behaviors in children and adolescents. A theoretical model is proposed to guide the development of future research.

  12. Report on preliminary analysis of state of nuclear criticality accident at JCO at Tokaimura, Ibaraki, Japan (I)

    Energy Technology Data Exchange (ETDEWEB)

    Ha, J.J.; Park, J.H.; Chang, J.H. [Korea Atomic Energy Research Institute, Taejon (Korea)

    1999-10-01

    This preliminary report was prepared by the Special Task Force Team of KAERI in order to analysis status of nuclear criticality accident broken out at 10:35 September 30, 1999 at JCO nuclear conversion test facility located at Tokaimura, Ibaraki, Japan. The report was consisted of accident summary of cause of accident summary of cause of accident and response by relevant organizations, and preliminary technical analysis of radiation exposure of JCO workers, analysis of cause of accident, and accident assessment and preventive actions against criticality accident. It is expected that JCO accident, Japan's first nuclear criticality accident, would make significant effects to Japan nuclear policy and would be also a good example to Korea future actions to be taken in use and development of nuclear energy. 63 refs., 3 figs., 1 tab. (Author)

  13. Global energy futures and human development: a framework for analysis

    Energy Technology Data Exchange (ETDEWEB)

    Pasternak, A.D. [Lawrence Livermore National Lab., CA (United States)

    2001-07-01

    This paper explores the relationship between measures of human well-being and consumption of energy and electricity. A correlation is shown between the United Nations Human Development Index (HDI) and annual per- capita electricity consumption for 60 populous countries comprising 90% of the world population. In this correlation, HDI reaches a maximum value when electricity consumption is about 4,000 kWh per person per year, well below consumption levels for most developed countries but also well above the level for developing countries. The correlation with electricity use is better than with total primary energy use. Global electricity consumption associated with a ''Human Development Scenario'' is estimated by adding to U.S. Department of Energy projections for the year 2020 increments of additional electricity consumption sufficient to reach 4,000 kWh per capita on a country-by-country basis. A roughly constant ratio of primary energy consumption to electric energy consumption is observed for countries with high levels of electricity use, and this ratio is used to estimate global primary energy consumption in the Human Development Scenario. The Human Development Scenario implies significantly greater global consumption of electricity and primary energy than do projections for 2020 by the DOE and others. (author)

  14. Global analysis of anthropogenic debris ingestion by sea turtles.

    Science.gov (United States)

    Schuyler, Qamar; Hardesty, Britta Denise; Wilcox, Chris; Townsend, Kathy

    2014-02-01

    Ingestion of marine debris can have lethal and sublethal effects on sea turtles and other wildlife. Although researchers have reported on ingestion of anthropogenic debris by marine turtles and implied incidences of debris ingestion have increased over time, there has not been a global synthesis of the phenomenon since 1985. Thus, we analyzed 37 studies published from 1985 to 2012 that report on data collected from before 1900 through 2011. Specifically, we investigated whether ingestion prevalence has changed over time, what types of debris are most commonly ingested, the geographic distribution of debris ingestion by marine turtles relative to global debris distribution, and which species and life-history stages are most likely to ingest debris. The probability of green (Chelonia mydas) and leatherback turtles (Dermochelys coriacea) ingesting debris increased significantly over time, and plastic was the most commonly ingested debris. Turtles in nearly all regions studied ingest debris, but the probability of ingestion was not related to modeled debris densities. Furthermore, smaller, oceanic-stage turtles were more likely to ingest debris than coastal foragers, whereas carnivorous species were less likely to ingest debris than herbivores or gelatinovores. Our results indicate oceanic leatherback turtles and green turtles are at the greatest risk of both lethal and sublethal effects from ingested marine debris. To reduce this risk, anthropogenic debris must be managed at a global level. © 2013 The Authors. Conservation Biology published by Wiley Periodicals, Inc., on behalf of the Society for Conservation Biology.

  15. A Knowledge-Based Analysis of Global Function Computation

    CERN Document Server

    Halpern, Joseph Y

    2007-01-01

    Consider a distributed system N in which each agent has an input value and each communication link has a weight. Given a global function, that is, a function f whose value depends on the whole network, the goal is for every agent to eventually compute the value f(N). We call this problem global function computation. Various solutions for instances of this problem, such as Boolean function computation, leader election, (minimum) spanning tree construction, and network determination, have been proposed, each under particular assumptions about what processors know about the system and how this knowledge can be acquired. We give a necessary and sufficient condition for the problem to be solvable that generalizes a number of well-known results. We then provide a knowledge-based (kb) program (like those of Fagin, Halpern, Moses, and Vardi) that solves global function computation whenever possible. Finally, we improve the message overhead inherent in our initial kb program by giving a counterfactual belief-based pro...

  16. Preliminary results on the EUCLID NISP stray-light and ghost analysis

    Science.gov (United States)

    Geis, Norbert; Grupp, Frank; Prieto, Eric; Bender, Ralf

    2015-09-01

    The EUCLID mission within the European Space Agencies 2015 - 2025 Cosmic Vision framework addresses cosmological questions related to dark matter and dark energy. EUCLID is equipped with two instruments that are simultaneously observing patches of > 0:5 square degree on the sky. The VIS visual light high spacial resolution imager and the NISP near infrared spectrometer and photometer are separated by a di-chroic beam splitter. With its large FoV (larger than the full moon disk), together with high demands on the optical performance and strong requirements on in flight stability lead to very challenging demands on alignment and post launch { post cool-down optical element position. In addition the demanding requirements from spectroscopy and galaxy photometry lead to a highly demanding stray light and ghost control need. With this paper we present a preliminary - PDR level - analysis of ghosting and stray light levels in the EUCLID NISP near infrared spectrometer and photometer. The analysis presented focuses on the photometric channel, as this, together with the wide field of the instrument, shows most of the challenges and features of the instrument. As one requirement is to have a non vignetting design, extensive baffling is not possible, and only secondary and higher order light can be actively baffled. A comprehensive ZEMAX based analysis is being presented, showing in summary that baffles are only necessary due to the EUCLID fine guiding sensors auxiliary fields of view. The total level of contaminating light is thereafter dominated by stray light from dust on the lenses. Ghosts play a minor role.

  17. Global Analysis of Anthropogenic Debris Ingestion by Sea Turtles

    Science.gov (United States)

    Schuyler, Qamar; Hardesty, Britta Denise; Wilcox, Chris; Townsend, Kathy

    2014-01-01

    Ingestion of marine debris can have lethal and sublethal effects on sea turtles and other wildlife. Although researchers have reported on ingestion of anthropogenic debris by marine turtles and implied incidences of debris ingestion have increased over time, there has not been a global synthesis of the phenomenon since 1985. Thus, we analyzed 37 studies published from 1985 to 2012 that report on data collected from before 1900 through 2011. Specifically, we investigated whether ingestion prevalence has changed over time, what types of debris are most commonly ingested, the geographic distribution of debris ingestion by marine turtles relative to global debris distribution, and which species and life-history stages are most likely to ingest debris. The probability of green (Chelonia mydas) and leatherback turtles (Dermochelys coriacea) ingesting debris increased significantly over time, and plastic was the most commonly ingested debris. Turtles in nearly all regions studied ingest debris, but the probability of ingestion was not related to modeled debris densities. Furthermore, smaller, oceanic-stage turtles were more likely to ingest debris than coastal foragers, whereas carnivorous species were less likely to ingest debris than herbivores or gelatinovores. Our results indicate oceanic leatherback turtles and green turtles are at the greatest risk of both lethal and sublethal effects from ingested marine debris. To reduce this risk, anthropogenic debris must be managed at a global level. Análisis Global de la Ingesta de Residuos Antropogénicos por Tortugas Marinas La ingesta de residuos marinos puede tener efectos letales y subletales sobre las tortugas marinas y otros animales. Aunque hay investigadores que han reportado la ingesta de residuos antropogénicos por tortugas marinas y la incidencia de la ingesta de residuos ha incrementado con el tiempo, no ha habido una síntesis global del fenómeno desde 1985. Por esto analizamos 37 estudios publicados, desde

  18. Crystallization and preliminary X-ray analysis of Chandipura virus glycoprotein G.

    Science.gov (United States)

    Baquero, Eduard; Buonocore, Linda; Rose, John K; Bressanelli, Stéphane; Gaudin, Yves; Albertini, Aurélie A

    2012-09-01

    Fusion in members of the Rhabdoviridae virus family is mediated by the G glycoprotein. At low pH, the G glycoprotein catalyzes fusion between viral and endosomal membranes by undergoing a major conformational change from a pre-fusion trimer to a post-fusion trimer. The structure of the G glycoprotein from vesicular stomatitis virus (VSV G), the prototype of Vesiculovirus, has recently been solved in its trimeric pre-fusion and post-fusion conformations; however, little is known about the structural details of the transition. In this work, a soluble form of the ectodomain of Chandipura virus G glycoprotein (CHAV G(th)) was purified using limited proteolysis of purified virus; this soluble ectodomain was also crystallized. This protein shares 41% amino-acid identity with VSV G and thus its structure could provide further clues about the structural transition of rhabdoviral glycoproteins induced by low pH. Crystals of CHAV G(th) obtained at pH 7.5 diffracted X-rays to 3.1 Å resolution. These crystals belonged to the orthorhombic space group P2(1)2(1)2, with unit-cell parameters a = 150.3, b = 228.2, c = 78.8 Å. Preliminary analysis of the data based on the space group and the self-rotation function indicated that there was no trimeric association of the protomers. This unusual oligomeric status could result from the presence of fusion intermediates in the crystal.

  19. Preliminary uncertainty analysis of OECD/UAM benchmark for the TMI-1 reactor

    Energy Technology Data Exchange (ETDEWEB)

    Cardoso, Fabiano S.; Faria, Rochkhudson B.; Silva, Lucas M.C.; Pereira, Claubia; Fortini, Angela, E-mail: claubia@nuclear.ufmg.br [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Departamento de Engenharia Nuclear

    2015-07-01

    Nowadays the demand from nuclear research centers for safety, regulation and better-estimated predictions provided with confidence bounds has been increasing. On that way, studies have pointed out that present uncertainties in the nuclear data should be significantly reduced, to get the full benefit from the advanced modeling and simulation initiatives. The major outcome of NEA/OECD (UAM) workshop took place Italy on 2006, was the preparation of a benchmark work program with steps (exercises) that would be needed to define the uncertainty and modeling tasks. On that direction, this work was performed within the framework of UAM Exercise 1 (I-1) 'Cell Physics' to validate the study, and to be able estimated the accuracies of the model. The objectives of this study were to make a preliminary analysis of criticality values of TMI-1 PWR and the biases of the results from two different nuclear codes multiplication factor. The range of the bias was obtained using the deterministic codes: NEWT (New ESC-based Weighting Transport code), the two-dimensional transport module that uses AMPX-formatted cross-sections processed by other SCALE; and WIMSD5 (Winfrith Improved Multi-Group Scheme) code. The WIMSD5 system consists of a simplified geometric representation of heterogeneous space zones that are coupled with each other and with the boundaries, while the properties of each spacing element are obtained from Carlson DSN method or Collision Probability method. (author)

  20. In situ fluidization for peat bed rupture, and preliminary economic analysis.

    Science.gov (United States)

    Niven, R K; Khalili, N

    2002-11-01

    This study concerns in situ fluidization (ISF), a new remediation method with potential application to the remediation of NAPL and heavy metal contaminants, by their release from the fluidized zone generated by a water jet. The present study examines the effect of ISF on layers of peat, of significance owing to its role as an important NAPL and metal contaminant trap. Once trapped, such contaminants are not readily accessible by most remedial methods, due to the low permeability and diffusivity of the peat. A simple tank experiment is used to demonstrate rupture of a peat layer by ISF, with removal of the peat as elutriated fines and segregated peat chunks. The application of ISF in the field is then examined by three field trials in uncontaminated sands, in both saturated and unsaturated conditions. Fluidized depths of up to 1.9 m in the saturated zone (with refusal on a peat layer) and 2.5 m in the unsaturated zone (no refusal) were attained, using a 1.9-m-long, 50 mm diameter jet operated at 5-13 1 s(-1). Pulses of dark turbidity and shell fragments in the effluent indicated the rupture of peat and shelly layers. The experiments demonstrate the hydraulic viability of ISF in the field, and its ability to remove peat-based contaminants. The issues of appropriate jet design and water generation during ISF are discussed, followed by a preliminary economic analysis of ISF relative to existing remediation methods.

  1. Cloning, expression, crystallization and preliminary X-ray data analysis of norcoclaurine synthase from Thalictrum flavum

    Energy Technology Data Exchange (ETDEWEB)

    Pasquo, Alessandra [ENEA Casaccia Research Centre, Dipartimento BIOTEC, Sezione Genetica e Genomica Vegetale, PO Box 2400, I-00100 Rome (Italy); Bonamore, Alessandra; Franceschini, Stefano; Macone, Alberto; Boffi, Alberto; Ilari, Andrea, E-mail: andrea.ilari@uniroma1.it [Istituto di Biologia e Patologia Molecolari, CNR (IBPM) and Department Of Biochemical Sciences, University of Roma ‘La Sapienza’, Piazza Aldo Moro 5, 00179 Roma (Italy); ENEA Casaccia Research Centre, Dipartimento BIOTEC, Sezione Genetica e Genomica Vegetale, PO Box 2400, I-00100 Rome (Italy)

    2008-04-01

    The cloning, expression, crystallization and preliminary X-ray data analysis of norcoclaurine synthase from T. flavum, a protein which catalyzes the first committed step in the biosynthesis of benzylisoquinoline alkaloids, are reported. Norcoclaurine synthase (NCS) catalyzes the condensation of 3,4-dihydroxyphenylethylamine (dopamine) and 4-hydroxyphenylacetaldehyde (4-HPAA) as the first committed step in the biosynthesis of benzylisoquinoline alkaloids in plants. The protein was cloned, expressed and purified. Crystals were obtained at 294 K by the hanging-drop vapour-diffusion method using ammonium sulfate and sodium chloride as precipitant agents and diffract to better than 3.0 Å resolution using a synchrotron-radiation source. The crystals belong to the trigonal space group P3{sub 1}21, with unit-cell parameters a = b = 86.31, c = 118.36 Å. A selenomethionine derivative was overexpressed, purified and crystallized in the same space group. A complete MAD data set was collected at 2.7 Å resolution. The model is under construction.

  2. Acanthamoeba polyphaga mimivirus NDK: preliminary crystallographic analysis of the first viral nucleoside diphosphate kinase

    Energy Technology Data Exchange (ETDEWEB)

    Jeudy, Sandra [Information Génomique et Structurale, CNRS UPR 2589, 31 Chemin Joseph Aiguier, 13402 Marseille CEDEX 20 (France); Coutard, Bruno [Architecture et Fonction des Macromolecules Biologiques, CNRS UMR 6098, 31 Chemin Joseph Aiguier, 13402 Marseille CEDEX 20 (France); Lebrun, Régine [IBSM, 31 Chemin Joseph Aiguier, 13402 Marseille CEDEX 20 (France); Abergel, Chantal, E-mail: chantal.abergel@igs.cnrs-mrs.fr [Information Génomique et Structurale, CNRS UPR 2589, 31 Chemin Joseph Aiguier, 13402 Marseille CEDEX 20 (France)

    2005-06-01

    A. polyphaga mimivirus, the largest known double-stranded DNA virus, is the first virus to exhibit a nucleoside diphosphate kinase gene. The expression and crystallization of the viral NDK are reported. The complete sequence of the largest known double-stranded DNA virus, Acanthamoeba polyphaga mimivirus, has recently been determined [Raoult et al. (2004 ▶), Science, 306, 1344–1350] and revealed numerous genes not expected to be found in a virus. A comprehensive structural and functional study of these gene products was initiated [Abergel et al. (2005 ▶), Acta Cryst. F61, 212–215] both to better understand their role in the virus physiology and to obtain some clues to the origin of DNA viruses. Here, the preliminary crystallographic analysis of the viral nucleoside diphosphate kinase protein is reported. The crystal belongs to the cubic space group P2{sub 1}3, with unit-cell parameter 99.425 Å. The self-rotation function confirms that there are two monomers per asymmetric unit related by a twofold non-crystallographic axis and that the unit cell thus contains four biological entities.

  3. N-Acetyltransferase 2 status and gastric cancer risk: a preliminary meta-analysis

    Directory of Open Access Journals (Sweden)

    Stefania Boccia

    2005-03-01

    Full Text Available

    In recent studies N- Acetyltransferase 2 (NAT2 genotype has been considered as a risk factor for developing gastric cancer, however with conflicting results among Asian and Caucasian populations. In order to clarify the influence of NAT2 slow acetylation status on gastric cancer risk, a preliminary meta-analysis of published case-control studies was undertaken.

    The primary outcome measure was the odds ratio (OR for the risk of gastric cancer associated with the NAT2 slow genotype using a random effects model. Pooling the results from the 5 studies identified (771 cases, 1083 controls, an overall OR for gastric cancer risk associated with the NAT2 slow genotype of 0.91 emerged (95% CI: 0.54-1.55.

    The result suggests that the NAT2 slow genotype has probably no effect on the risk of gastric cancer. Additional epidemiological studies, based on sample sizes that are commensurate with the detection of small genotypic risks, are required to confirm these findings. Future studies may also help to clarify whether geographic differences exist.

  4. Preliminary Analysis of Two Years of the Massive Collision Monitoring Activity

    Science.gov (United States)

    McKnight, Darren; Matney, Mark; Walbert, Kris; Behrend, Sophie; Casey, Patrick; Speaks, Seth

    2017-01-01

    It is hypothesized that the interactions between many of the most massive derelicts in low Earth orbit are more frequent than modeled by the traditional combination of kinetic theory of gases and Poisson probability distribution function. This is suggested by the fact that there are clusters of derelicts where members' inclinations are nearly identical and their apogees/perigees overlap significantly resulting in periodic synchronization of the objects' orbits. In order to address this proposition, an experiment was designed and conducted over the last two years. Results from this monitoring and characterization experiment are presented with implications for proposed debris remediation strategies. Four separate clusters of massive derelicts were examined that are centered around 775km, 850km, 975km, and 1500km, respectively. In aggregate, the constituents of these clusters contain around 500 objects and about 800,000kg of mass; this equates to a third of all derelict mass in LEO. Preliminary analysis indicates that encounter rates over this time period for these objects are greater than is estimated by traditional techniques. Hypothesized dependencies between latitude of encounter, relative velocity, frequency of encounters, inclination, and differential semi-major axis were established and verified. This experiment also identified specific repeatable cluster dynamics that may reduce the cost/risk and enhance the effectiveness of debris remediation activities and also enable new operational debris remediation options.

  5. GC-MS Analysis and Preliminary Antimicrobial Activity of Albizia adianthifolia (Schumach and Pterocarpus angolensis (DC

    Directory of Open Access Journals (Sweden)

    Mustapha N. Abubakar

    2016-01-01

    Full Text Available The non-polar components of two leguminoceae species Albizia adianthifolia (Schumach, and Pterocarpus angolensis (DC were investigated. GC-MS analysis of the crude n-hexane and chloroform extracts together with several chromatographic separation techniques led to the identification and characterization (using NMR of sixteen known compounds from the heartwood and stem bark of Albizia adianthifolia and Pterocarpus angolensis respectively. These constituents include, n-hexadecanoic acid (palmitic acid 1, oleic acid 2, chondrillasterol 3, stigmasterol 4, 24S 5α-stigmast-7-en-3β-ol 5, 9,12-octadecadienoic acid (Z,Z-, methyl ester 6, trans-13-octadecanoic acid, methyl ester 7, tetradecanoic acid 8, hexadecanoic acid, methyl ester 9, octadecanoic acid 10, tetratriacontane 11, 7-dehydrodiosgenin 12, lupeol 13, stigmasta-3,5-diene-7-one 14, friedelan-3-one (friedelin 15, and 1-octacosanol 16. Using agar over lay method, the preliminary antimicrobial assay for the extracts was carried out against bacterial (E. coli, P. aeruginosa, B. subtilis, S. aueus and a fungus/yeast (C. albicans strains. The n-hexane and chloroform extracts of A. adianthifolia showed the best activity against E. coli with minimum inhibition quantity (MIQ of 1 µg each while the remaining exhibited moderate-to-weak activity against the test microorganisms.

  6. Satellite geological and geophysical remote sensing of Iceland: Preliminary results from analysis of MSS imagery

    Science.gov (United States)

    Williams, R. S., Jr.; Boedvarsson, A.; Fridriksson, S.; Palmason, G.; Rist, S.; Sigtryggsson, H.; Thorarinsson, S.; Thorsteinsson, I.

    1973-01-01

    A binational, multidisciplinary research effort in Iceland is directed at an analysis of MSS imagery from ERTS-1 to study a variety of geologic, hydrologic, oceanographic, and agricultural phenomena. A preliminary evaluation of available MSS imagery of Iceland has yielded several significant results - some of which may have direct importance to the Icelandic economy. Initial findings can be summarized as follows: (1) recent lava flows can be delineated from older flows at Askja and Hekla; (2) MSS imagery from ERTS-1 and VHRR visible and infrared imagery from NOAA-2 recorded the vocanic eruption on Heimaey, Vestmann Islands; (3) coastline changes, particularly changes in the position of bars and beaches along the south coast are mappable; and (4) areas covered with new and residual snow can be mapped, and the appearance of newly fallen snow on ERTS-1, MSS band 7 appears dark where it is melting. ERTS-1 imagery provides a means of updating various types of maps of Iceland and will permit the compilation of special maps specifically aimed at those dynamic environmental phenomena which impact on the Icelandic economy.

  7. Analysis of the preliminary optical links between ARTEMIS and the Optical Ground Station

    Science.gov (United States)

    Reyes Garcia-Talavera, Marcos; Chueca, Sergio; Alonso, Angel; Viera, Teodora; Sodnik, Zoran

    2002-12-01

    In the frame of the SILEX project, the European Space Agency (ESA) has put into orbit two Laser Communication Terminals, to establish an experimental free space optical communication link between a GEO satellite (ARTEMIS) and a LEO satellite (SPOT IV), to relay earth observation data. In order to perform In Orbit Testing (IOT) of these, and other, optical communications systems, ESA and the Instituto de Astrofisica de Canarias (IAC) reached an agreement for building the Optical Ground Station (OGS), in the Teide Observatory of the IAC. With ARTEMIS placed in a circular parking orbit at about 31000 kilometres, its optical payload has been preliminary tested with the OGS. First results and analysis are presented on the space-to-ground bi-directional link, including pointing acquisition and tracking performance, Bit-Error Rate (BER) and transmitted beam divergence effects related with atmospheric models and predictions. Future plans include deeper optical bi-directional communication tests of OGS, not only with ARTEMIS but also with OSCAR-40 (downlink) and SMART-1 (up-link) satellites, in order to do a full characterisation of the performances of laser beam propagation through atmospheric turbulence and a comparison with theoretical predictions.

  8. Marine Traffic Density Over Port Klang, Malaysia Using Statistical Analysis of AIS Data: A Preliminary Study

    Directory of Open Access Journals (Sweden)

    Masnawi MUSTAFFA

    2016-12-01

    Full Text Available Port Klang Malaysia is the 13th busiest port in the world, the capacity at the port expected to be able to meet the demand until 2018. It is one of the busiest ports in the world and also the busiest port in Malaysia. Even though there are statistics published by Port Klang Authority showing that a lot of ships using this port, this number is only based on ships that entering Port Klang. Therefore, no study has been done to investigate on how dense the traffic is in Port Klang, Malaysia the surrounding sea including Strait of Malacca . This paper has investigated on traffic density over Port Klang Malaysia and its surrounding sea using statistical analysis from AIS data. As a preliminary study, this study only collected AIS data for 7 days to represent daily traffic weekly. As a result, an hourly number of vessels, daily number of vessels, vessels classification and sizes and also traffic paths will be plotted.

  9. GC-MS Analysis and Preliminary Antimicrobial Activity of Albizia adianthifolia (Schumach) and Pterocarpus angolensis (DC).

    Science.gov (United States)

    Abubakar, Mustapha N; Majinda, Runner R T

    2016-01-28

    The non-polar components of two leguminoceae species Albizia adianthifolia (Schumach), and Pterocarpus angolensis (DC) were investigated. GC-MS analysis of the crude n-hexane and chloroform extracts together with several chromatographic separation techniques led to the identification and characterization (using NMR) of sixteen known compounds from the heartwood and stem bark of Albizia adianthifolia and Pterocarpus angolensis respectively. These constituents include, n-hexadecanoic acid (palmitic acid) 1, oleic acid 2, chondrillasterol 3, stigmasterol 4, 24S 5α-stigmast-7-en-3β-ol 5, 9,12-octadecadienoic acid (Z,Z)-, methyl ester 6, trans-13-octadecanoic acid, methyl ester 7, tetradecanoic acid 8, hexadecanoic acid, methyl ester 9, octadecanoic acid 10, tetratriacontane 11, 7-dehydrodiosgenin 12, lupeol 13, stigmasta-3,5-diene-7-one 14, friedelan-3-one (friedelin) 15, and 1-octacosanol 16. Using agar over lay method, the preliminary antimicrobial assay for the extracts was carried out against bacterial (E. coli, P. aeruginosa, B. subtilis, S. aueus) and a fungus/yeast (C. albicans) strains. The n-hexane and chloroform extracts of A. adianthifolia showed the best activity against E. coli with minimum inhibition quantity (MIQ) of 1 µg each while the remaining exhibited moderate-to-weak activity against the test microorganisms.

  10. Bioinformatics analysis of the gene expression profile of hepatocellular carcinoma: preliminary results

    Science.gov (United States)

    Li, Jia

    2016-01-01

    Aim of the study To analyse the expression profile of hepatocellular carcinoma compared with normal liver by using bioinformatics methods. Material and methods In this study, we analysed the microarray expression data of HCC and adjacent normal liver samples from the Gene Expression Omnibus (GEO) database to screen for differentially expressed genes. Then, functional analyses were performed using GenCLiP analysis, Gene Ontology categories, and aberrant pathway identification. In addition, we used the CMap database to identify small molecules that can induce HCC. Results Overall, 2721 differentially expressed genes (DEGs) were identified. We found 180 metastasis-related genes and constructed co-occurrence networks. Several significant pathways, including the transforming growth factor β (TGF-β) signalling pathway, were identified as closely related to these DEGs. Some candidate small molecules (such as betahistine) were identified that might provide a basis for developing HCC treatments in the future. Conclusions Although we functionally analysed the differences in the gene expression profiles of HCC and normal liver tissues, our study is essentially preliminary, and it may be premature to apply our results to clinical trials. Further research and experimental testing are required in future studies. PMID:27095935

  11. Occupant evaluation of commercial office lighting: Volume 2, Preliminary data analysis

    Energy Technology Data Exchange (ETDEWEB)

    Marans, R.W.; Brown, M.A. (ed.)

    1987-11-01

    This report presents the preliminary results of a post-occupancy evaluation of office lighting environments. It explores the relationship between quantitative measures of lighting in occupied environments and qualitative measures related to occupant satisfaction. The report analyzes several types of data from more than 1000 occupied work stations: subjective data on attitudes and ratings of selected lighting and other characteristics, photometric and other direct environmental data, including illuminances, luminances, and contrast conditions, indirect environmental measures obtained from the architectural drawings and the work station photographs, and descriptive characteristics of the occupants. The work stations were sampled from thirteen office buildings located in various cities in the United States. Many tentative findings emerged from the analysis, including the following: (1) within the range of values examined here, there is a tendency for lighting satisfaction to decrease as lighting power density increases; (2) occupants who described their work station spaces as bright also tended to be satisfied with their work station lighting; (3) occupants who were most bothered by bright lights and glare were most likely to express dissatisfaction with the lighting at their work stations; (4) there is no relationship between work-related activities of employees and indicators of lighting quality. More research is needed before firm conclusions can be drawn and before guidance regarding lighting standards and other policy issues can be derived. 3 refs., 9 figs.

  12. Hydrothermal Liquefaction and Upgrading of Municipal Wastewater Treatment Plant Sludge: A Preliminary Techno-Economic Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Snowden-Swan, Lesley J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Zhu, Yunhua [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Jones, Susanne B. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Elliott, Douglas C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Schmidt, Andrew J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hallen, Richard T. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Billing, Justin M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hart, Todd R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Fox, Samuel P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Maupin, Gary D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-06-08

    A preliminary process model and techno-economic analysis (TEA) was completed for fuel produced from hydrothermal liquefaction (HTL) of sludge waste from a municipal wastewater treatment plant (WWTP) and subsequent biocrude upgrading. The model is adapted from previous work by Jones et al. (2014) for algae HTL, using experimental data generated in fiscal year 2015 (FY15) bench-scale HTL testing of sludge waste streams. Testing was performed on sludge samples received from MetroVancouver’s Annacis Island WWTP (Vancouver, B.C.) as part of a collaborative project with the Water Environment and Reuse Foundation (WERF). The full set of sludge HTL testing data from this effort will be documented in a separate report to be issued by WERF. This analysis is based on limited testing data and therefore should be considered preliminary. Future refinements are necessary to improve the robustness of the model, including a cross-check of modeled biocrude components with the experimental GCMS data and investigation of equipment costs most appropriate at the smaller scales used here. Environmental sustainability metrics analysis is also needed to understand the broader impact of this technology pathway. The base case scenario for the analysis consists of 10 HTL plants, each processing 100 dry U.S. ton/day (92.4 ton/day on a dry, ash-free basis) of sludge waste and producing 234 barrel per stream day (BPSD) biocrude, feeding into a centralized biocrude upgrading facility that produces 2,020 barrel per standard day of final fuel. This scale was chosen based upon initial wastewater treatment plant data collected by the resource assessment team from the EPA’s Clean Watersheds Needs Survey database (EPA 2015a) and a rough estimate of what the potential sludge availability might be within a 100-mile radius. In addition, we received valuable feedback from the wastewater treatment industry as part of the WERF collaboration that helped form the basis for the selected HTL and upgrading

  13. Brook trout (Salvelinus fontinalis extinction in small boreal lakes revealed by ephippia pigmentation: a preliminary analysis

    Directory of Open Access Journals (Sweden)

    Alexandre Bérubé Tellier

    2016-12-01

    Full Text Available Ephippium pigmentation is a plastic trait which can be related to a trade-off between visual predation pressure and better protection of cladoceran eggs against different types of stress. Experimental studies showed that planktivorous fish exert a greater predation pressure on individuals carrying darker ephippia, but little is known about the variation of ephippium pigmentation along gradients of fish predation pressure in natural conditions. For this study, our experimental design included four small boreal lakes with known fish assemblages. Two of the lakes have viable brook trout (Salvelinus fontinalis populations, whereas the other two lakes experienced brook trout extinctions during the 20th century. Cladoceran ephippia were extracted from sediment cores at layers corresponding to the documented post- extinction phase (1990's and from an older layer (1950's for which the brook trout population status is not known precisely. Our first objective was to determine whether brook trout extinction has a direct effect on both ephippium pigmentation and size. Our second objective was to give a preliminary assessment of the status of brook trout populations in the 1950's by comparing the variation in ephippia traits measured from this layer to those measured in the 1990's, for which the extinction patterns are well known. Cost-effective image analysis was used to assess variation in pigmentation levels in ephippia. This approach provided a proxy for the amount of melanin invested in each ephippium analysed. Our study clearly shows that ephippium pigmentation may represent a better indicator of the presence of fish predators than ephippium size, a trait that showed a less clear pattern of variation between lakes with and without fish. For the 1990's period, ephippia from fishless lakes were darker and showed a slight tendency to be larger than ephippia from lakes with brook trout. However, no clear differences in either ephippium size or pigmentation

  14. GHRSST Level 4 MW_OI Global Foundation Sea Surface Temperature analysis (GDS version 2)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A Group for High Resolution Sea Surface Temperature (GHRSST) global Level 4 sea surface temperature analysis produced daily on a 0.25 degree grid at Remote Sensing...

  15. A geometrical formulation of the renormalization group method for global analysis

    CERN Document Server

    Kunihiro, T

    1995-01-01

    On the basis of the classical theory of envelope,we formulate the renormalization group (RG) method for global analysis, recently proposed by Goldenfeld et al. It is clarified why the RG equation improves things.

  16. GHRSST Level 4 AVHRR_AMSR_OI Global Blended Sea Surface Temperature Analysis (GDS version 1)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A Group for High Resolution Sea Surface Temperature (GHRSST) global Level 4 sea surface temperature analysis produced daily on a 0.25 degree grid at the NOAA...

  17. Global analysis of overweight prevalence by level of human development

    Directory of Open Access Journals (Sweden)

    Carmen D Ng

    2016-02-01

    Full Text Available Less developed countries are increasingly afflicted with over–nutrition, and the escalating overweight prevalence has become a global problem. However, a problem as global as this may not be amenable to a general set of remedial interventions applicable to all countries. I use data from various sources, including the World Health Organization and the World Bank, to test the association of overweight prevalence with economic, social, and demographic indicators. I then split the countries up by human development index to investigate to what extent these associations vary between development levels. On a global scale, overweight prevalence is most associated with gross domestic product (GDP per capita, the proportion of a country that is rural, the proportion of elderly in a country's population, and the average years of schooling. At what magnitude, and even in which direction, these relationships go vary with a country's level of development. Generally, GDP per capita has a positive association with overweight prevalence, with the magnitude of such association for countries of very high human development more than twice of that for countries of low human development. However, proportion rural has a negative association with overweight prevalence, with the magnitude of such association for countries of low human development nearly twice of that for countries of very high human development. All four of these variables have statistically significant association with overweight prevalence in countries with low human development. I make policy suggestions to combat increasing overweight prevalence, based on the models that are developed, paying special attention to the differences in magnitude and direction of the regressors between human development levels.

  18. Global analysis of overweight prevalence by level of human development.

    Science.gov (United States)

    Ng, Carmen D

    2015-12-01

    Less developed countries are increasingly afflicted with over-nutrition, and the escalating overweight prevalence has become a global problem. However, a problem as global as this may not be amenable to a general set of remedial interventions applicable to all countries. I use data from various sources, including the World Health Organization and the World Bank, to test the association of overweight prevalence with economic, social, and demographic indicators. I then split the countries up by human development index to investigate to what extent these associations vary between development levels. On a global scale, overweight prevalence is most associated with gross domestic product (GDP) per capita, the proportion of a country that is rural, the proportion of elderly in a country's population, and the average years of schooling. At what magnitude, and even in which direction, these relationships go vary with a country's level of development. Generally, GDP per capita has a positive association with overweight prevalence, with the magnitude of such association for countries of very high human development more than twice of that for countries of low human development. However, proportion rural has a negative association with overweight prevalence, with the magnitude of such association for countries of low human development nearly twice of that for countries of very high human development. All four of these variables have statistically significant association with overweight prevalence in countries with low human development. I make policy suggestions to combat increasing overweight prevalence, based on the models that are developed, paying special attention to the differences in magnitude and direction of the regressors between human development levels.

  19. COMPARATIVE ANALYSIS OF RUSSIA’S AND CHINA’S PARTICIPATING IN GLOBAL GOVERNANCE INSTITUTIONS EXPERIENCE

    Directory of Open Access Journals (Sweden)

    Vladimir E. Petrovskiy

    2015-01-01

    Full Text Available The article deals with the comparative analysis of Russian and Chinese participation in the current system of global governance, and in its reform. The author views participation of the respective countries in the system of global governance as part of their foreign policy and foreign policy strategy. He shows common and distinctive features of conceptual and practical approaches towards global governance defined by specific features of Russia’s and China’s history, economic development, political culture and traditions. Based on this comparative analysis, the author speculates on the future trends of participation of the two countries in the global governance system, in the spheres of global economy and international security, and on the future trends of their policy coordination in these respective areas.

  20. Frequency analysis of nonlinear oscillations via the global error minimization

    Science.gov (United States)

    Kalami Yazdi, M.; Hosseini Tehrani, P.

    2016-06-01

    The capacity and effectiveness of a modified variational approach, namely global error minimization (GEM) is illustrated in this study. For this purpose, the free oscillations of a rod rocking on a cylindrical surface and the Duffing-harmonic oscillator are treated. In order to validate and exhibit the merit of the method, the obtained result is compared with both of the exact frequency and the outcome of other well-known analytical methods. The corollary reveals that the first order approximation leads to an acceptable relative error, specially for large initial conditions. The procedure can be promisingly exerted to the conservative nonlinear problems.

  1. Spatial behavior analysis at the global level using fractal geometry.

    Science.gov (United States)

    Sambrook, Roger C

    2008-01-01

    Previous work has suggested that an estimate of fractal dimension can provide a useful metric for quantifying settlement patterns. This study uses fractal methods to investigate settlement patterns at a global scale showing that the scaling behavior of the pattern of the world's largest cities corresponds to that typically observed for coastlines and rivers. This serves to validate the use of fractal dimension as a scale-independent measure of settlement patterns which can be correlated with other physical features. Such a measure may be a useful validation criterion for models of human settlement and spatial behavior.

  2. Gene expression analysis identifies global gene dosage sensitivity in cancer

    DEFF Research Database (Denmark)

    Fehrmann, Rudolf S. N.; Karjalainen, Juha M.; Krajewska, Malgorzata;

    2015-01-01

    expression. We reanalyzed 77,840 expression profiles and observed a limited set of 'transcriptional components' that describe well-known biology, explain the vast majority of variation in gene expression and enable us to predict the biological function of genes. On correcting expression profiles...... for these components, we observed that the residual expression levels (in 'functional genomic mRNA' profiling) correlated strongly with copy number. DNA copy number correlated positively with expression levels for 99% of all abundantly expressed human genes, indicating global gene dosage sensitivity. By applying...

  3. NGS meta data analysis for identification of SNP and INDEL patterns in human airway transcriptome: A preliminary indicator for lung cancer

    Directory of Open Access Journals (Sweden)

    Sathya B.

    2015-03-01

    Full Text Available High-throughput sequencing of RNA (RNA-Seq was developed primarily to analyze global gene expression in different tissues. It is also an efficient way to discover coding SNPs and when multiple individuals with different genetic backgrounds were used, RNA-Seq is very effective for the identification of SNPs. The objective of this study was to perform SNP and INDEL discoveries in human airway transcriptome of healthy never smokers, healthy current smokers, smokers without lung cancer and smokers with lung cancer. By preliminary comparative analysis of these four data sets, it is expected to get SNP and INDEL patterns responsible for lung cancer. A total of 85,028 SNPs and 5738 INDELs in healthy never smokers, 32,671 SNPs and 1561 INDELs in healthy current smokers, 50,205 SNPs and 3008 INDELs in smokers without lung cancer and 51,299 SNPs and 3138 INDELs in smokers with lung cancer were identified. The analysis of the SNPs and INDELs in genes that were reported earlier as differentially expressed was also performed. It has been found that a smoking person has SNPs at position 62,186,542 and 62,190,293 in SCGB1A1 gene and 180,017,251, 180,017,252, and 180,017,597 in SCGB3A1 gene and INDELs at position 35,871,168 in NFKBIA gene and 180,017,797 in SCGB3A1 gene. The SNPs identified in this study provides a resource for genetic studies in smokers and shall contribute to the development of a personalized medicine. This study is only a preliminary kind and more vigorous data analysis and wet lab validation are required.

  4. Preliminary Analysis of Effects of Reduced Discharge onThermal Habitat of Pedersen Warm Springs Channel

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — A preliminary report to study the potential impacts of possible flow reductions in thermal spring systems located in the Warm Springs area of Moapa Valley NWR on the...

  5. Pharmacognostic and Preliminary Phytochemical Analysis of Sauropus androgynus (L) Merr. Leaf

    OpenAIRE

    Ankad Gireesh; Hegde Harsha; Kholkute S.D; Hurkadale Pramod

    2013-01-01

    The leaves of Sauropus androgynus (L.) Merr. are used in traditional medicine to treat various disorders and also used as vegetable for its nutritive value. Such plant having medicinal and nutritive values lacks pharmacognostical and preliminary phytochemical information. Hence the present work is intended to study pharmacognostical and preliminary phytochemical studies, which will serve as quality control parameters. The pharmacognostical parameters like transverse section of midrib, epiderm...

  6. Mars Global Surveyor Ka-Band Frequency Data Analysis

    Science.gov (United States)

    Morabito, D.; Butman, S.; Shambayati, S.

    2000-01-01

    The Mars Global Surveyor (MGS) spacecraft, launched on November 7, 1996, carries an experimental space-to-ground telecommunications link at Ka-band (32 GHz) along with the primary X-band (8.4 GHz) downlink. The signals are simultaneously transmitted from a 1.5-in diameter parabolic high gain antenna (HGA) on MGS and received by a beam-waveguide (BWG) R&D 34-meter antenna located in NASA's Goldstone Deep Space Network (DSN) complex near Barstow, California. The projected 5-dB link advantage of Ka-band relative to X-band was confirmed in previous reports using measurements of MGS signal strength data acquired during the first two years of the link experiment from December 1996 to December 1998. Analysis of X-band and Ka-band frequency data and difference frequency (fx-fka)/3.8 data will be presented here. On board the spacecraft, a low-power sample of the X-band downlink from the transponder is upconverted to 32 GHz, the Ka-band frequency, amplified to I-W using a Solid State Power Amplifier, and radiated from the dual X/Ka HGA. The X-band signal is amplified by one of two 25 W TWTAs. An upconverter first downconverts the 8.42 GHz X-band signal to 8 GHz and then multiplies using a X4 multiplier producing the 32 GHz Ka-band frequency. The frequency source selection is performed by an RF switch which can be commanded to select a VCO (Voltage Controlled Oscillator) or USO (Ultra-Stable Oscillator) reference. The Ka-band frequency can be either coherent with the X-band downlink reference or a hybrid combination of the USO and VCO derived frequencies. The data in this study were chosen such that the Ka-band signal is purely coherent with the X-band signal, that is the downconverter is driven by the same frequency source as the X-band downlink). The ground station used to acquire the data is DSS-13, a 34-meter BWG antenna which incorporates a series of mirrors inside beam waveguide tubes which guide the energy to a subterranean pedestal room, providing a stable environment

  7. Volume analysis of heat-induced cracks in human molars: A preliminary study

    Directory of Open Access Journals (Sweden)

    Michael A. Sandholzer

    2014-01-01

    Full Text Available Context: Only a few methods have been published dealing with the visualization of heat-induced cracks inside bones and teeth. Aims : As a novel approach this study used nondestructive X-ray microtomography (micro-CT for volume analysis of heat-induced cracks to observe the reaction of human molars to various levels of thermal stress. Materials and Methods: Eighteen clinically extracted third molars were rehydrated and burned under controlled temperatures (400, 650, and 800°C using an electric furnace adjusted with a 25°C increase/min. The subsequent high-resolution scans (voxel-size 17.7 μm were made with a compact micro-CT scanner (SkyScan 1174. In total, 14 scans were automatically segmented with Definiens XD Developer 1.2 and three-dimensional (3D models were computed with Visage Imaging Amira 5.2.2. The results of the automated segmentation were analyzed with an analysis of variance (ANOVA and uncorrected post hoc least significant difference (LSD tests using Statistical Package for Social Sciences (SPSS 17. A probability level of P < 0.05 was used as an index of statistical significance. Results: A temperature-dependent increase of heat-induced cracks was observed between the three temperature groups (P < 0.05, ANOVA post hoc LSD. In addition, the distributions and shape of the heat-induced changes could be classified using the computed 3D models. Conclusion: The macroscopic heat-induced changes observed in this preliminary study correspond with previous observations of unrestored human teeth, yet the current observations also take into account the entire microscopic 3D expansions of heat-induced cracks within the dental hard tissues. Using the same experimental conditions proposed in the literature, this study confirms previous results, adds new observations, and offers new perspectives in the investigation of forensic evidence.

  8. Early detection of breast cancer using total biochemical analysis of peripheral blood components: a preliminary study.

    Science.gov (United States)

    Zelig, Udi; Barlev, Eyal; Bar, Omri; Gross, Itai; Flomen, Felix; Mordechai, Shaul; Kapelushnik, Joseph; Nathan, Ilana; Kashtan, Hanoch; Wasserberg, Nir; Madhala-Givon, Osnat

    2015-05-15

    Most of the blood tests aiming for breast cancer screening rely on quantification of a single or few biomarkers. The aim of this study was to evaluate the feasibility of detecting breast cancer by analyzing the total biochemical composition of plasma as well as peripheral blood mononuclear cells (PBMCs) using infrared spectroscopy. Blood was collected from 29 patients with confirmed breast cancer and 30 controls with benign or no breast tumors, undergoing screening for breast cancer. PBMCs and plasma were isolated and dried on a zinc selenide slide and measured under a Fourier transform infrared (FTIR) microscope to obtain their infrared absorption spectra. Differences in the spectra of PBMCs and plasma between the groups were analyzed as well as the specific influence of the relevant pathological characteristics of the cancer patients. Several bands in the FTIR spectra of both blood components significantly distinguished patients with and without cancer. Employing feature extraction with quadratic discriminant analysis, a sensitivity of ~90 % and a specificity of ~80 % for breast cancer detection was achieved. These results were confirmed by Monte Carlo cross-validation. Further analysis of the cancer group revealed an influence of several clinical parameters, such as the involvement of lymph nodes, on the infrared spectra, with each blood component affected by different parameters. The present preliminary study suggests that FTIR spectroscopy of PBMCs and plasma is a potentially feasible and efficient tool for the early detection of breast neoplasms. An important application of our study is the distinction between benign lesions (considered as part of the non-cancer group) and malignant tumors thus reducing false positive results at screening. Furthermore, the correlation of specific spectral changes with clinical parameters of cancer patients indicates for possible contribution to diagnosis and prognosis.

  9. An evaluation of the Positive Emotional Experiences Scale: A preliminary analysis

    Directory of Open Access Journals (Sweden)

    Rene van Wyk

    2016-04-01

    Full Text Available Orientation: The positive organisational behaviour movement emphasises the advantages of psychological strengths in business. The psychological virtues of positive emotional experiences can potentially promote human strengths to the advantages of business functioning and the management of work conditions. This is supported by Fredrickson’s broaden-and-build theory that emphasises the broadening of reactive thought patterns through experiences of positive emotions.Research purpose: A preliminary psychometric evaluation of a positive measurement of dimensions of emotional experiences in the workplace, by rephrasing the Kiefer and Barclay Toxic Emotional Experiences Scale.Motivation for the study: This quantitative Exploratory Factor Analysis investigates the factorial structure and reliability of the Positive Emotional Experiences Scale, a positive rephrased version of the Toxic Emotional Experiences Scale.Research approach, design and method: This Exploratory Factor Analysis indicates an acceptable three-factor model for the Positive Emotional Experiences Scale. These three factors are: (1 psychological recurrent positive state, (2 social connectedness and (3 physical refreshed energy, with strong Cronbach’s alphas of 0.91, 0.91 and 0.94, respectively.Main findings: The three-factor model of the Positive Emotional Experiences Scale provides a valid measure in support of Fredrickson’s theory of social, physical and psychological endured personal resources that build positive emotions.Practical/Managerial implications: Knowledge gained on positive versus negative emotional experiences could be applied by management to promote endured personal resources that strengthen positive emotional experiences.Contribution/value-add: The contribution of this rephrased Positive Emotional Experiences Scale provides a reliable measure of assessment of the social, physical and endured psychological and personal resources identified in Fredrickson’s broaden

  10. Uncertainty analysis and global sensitivity analysis of techno-economic assessments for biodiesel production.

    Science.gov (United States)

    Tang, Zhang-Chun; Zhenzhou, Lu; Zhiwen, Liu; Ningcong, Xiao

    2015-01-01

    There are various uncertain parameters in the techno-economic assessments (TEAs) of biodiesel production, including capital cost, interest rate, feedstock price, maintenance rate, biodiesel conversion efficiency, glycerol price and operating cost. However, fewer studies focus on the influence of these parameters on TEAs. This paper investigated the effects of these parameters on the life cycle cost (LCC) and the unit cost (UC) in the TEAs of biodiesel production. The results show that LCC and UC exhibit variations when involving uncertain parameters. Based on the uncertainty analysis, three global sensitivity analysis (GSA) methods are utilized to quantify the contribution of an individual uncertain parameter to LCC and UC. The GSA results reveal that the feedstock price and the interest rate produce considerable effects on the TEAs. These results can provide a useful guide for entrepreneurs when they plan plants.

  11. Technological Strategy of Using Global Positioning System: An Analysis

    CERN Document Server

    Ahamed, S S Riaz

    2010-01-01

    The Global Positioning System (GPS) is a U.S. space-based radionavigation system that provides reliable positioning, navigation, and timing services to civilian users on a continuous worldwide basis -- freely available to all. GPS provides specially coded satellite signals that can be processed in a GPS receiver, enabling the receiver to compute position, velocity and time. Basically GPS works by using four GPS satellite signals to compute positions in three dimensions (and the time offset) in the receiver clock. GPS provides accurate location and time information for an unlimited number of people in all weather, day and night, anywhere in the world. Anyone who needs to keep track of where he or she is, to find his or her way to a specified location, or know what direction and how fast he or she is going can utilize the benefits of the global positioning system. Everyday activities such as banking, mobile phone operations, and even the control of power grids, are facilitated by the accurate timing provided by...

  12. Globalization, economic freedom, and wage inequality: A panel data analysis

    Directory of Open Access Journals (Sweden)

    Yay Gülsün

    2016-01-01

    Full Text Available This paper examines the impact of globalization and liberalization on wage inequality using the KOF globalization index, the Economic Freedom Index (EFI of the Fraser Institute and the Theil industrial pay inequality statistic compiled by the University of Texas Inequality Project (UTIP. Both static and dynamic fixedeffects models are estimated using a 5-year panel data set consisting of about 90 developed and developing countries for the 1970-2005 period. Estimation results from the dynamic panel data specification suggest that wage inequality has a significant and slowly changing component. The overall KOF and EFI indexes are found to be statistically insignificant in the full sample, but the results show that economic freedom is associated with more wage inequality, especially in Organisation for Economic Co-operation and Development (OECD countries. The estimation results from country groups indicate that more deregulation is associated with more earnings inequality in OECD countries. The results from the models with subcomponents of the EFI imply that access to sound money has a negative effect on wage inequality. A more stable price system in an economy implies a more equal wage distribution in emerging markets (EM, non-OECD countries, and European Union (EU.

  13. GEOPOLITICS - A NEW FRAMEWORK OF ANALYSIS: GLOBAL CHALLENGES AND PERSPECTIVES

    Directory of Open Access Journals (Sweden)

    Laura Cătălina PAȘCU

    2015-04-01

    Full Text Available Geopolitics born at the end of the 19th century and reborn at the end of the 20th century, from the need to explain certain issues arising out of the general evolution of human society and the growing influence of permanent politico-economic changes on the human consciousness and the entire system of socio-political life and culture. Also, geopolitics gives us the opportunity to reflect on the manifestation and evolution of power relations within a particular historical period, to assess and track changes and trends in the current system of international relations, giving us indicators and analytical methods about the reality of international relations. The relations of competition versus cooperation between international actors have changed gradually in the 21st century; however, development cooperation can provide solutions or opportunities for defining global problems. Globalization creates a new framework in security and international relations also introduced the geo-economics perspectives to assumed new found geopolitical importance at the outset of the twenty-first century.

  14. Technological Strategy of using Global Positioning System: An Analysis

    Directory of Open Access Journals (Sweden)

    Dr.S.S.Riaz Ahamed

    2009-10-01

    Full Text Available The Global Positioning System (GPS is a U.S. space-based radionavigation system that provides reliable positioning, navigation, and timing services to civilian users on a continuous worldwide basis -- freely available to all. GPS provides specially coded satellite signals that can be processed in a GPS receiver, enabling the receiver to compute position, velocity and time. Basically GPS works by using four GPS satellite signals to compute positions in three dimensions (and the time offset in the receiver clock. GPS provides accurate location and time information for an unlimited number of people in all weather, day and night, anywhere in the world. Anyone who needs to keep track of where he or she is, to find his or her way to a specified location, or know what direction and how fast he or she is going can utilize the benefits of the global positioning system. Everyday activities such as banking, mobile phone operations, and even the control of power grids, are facilitated by the accurate timing provided by GPS.

  15. Water footprint scenarios for 2050: a global analysis.

    Science.gov (United States)

    Ercin, A Ertug; Hoekstra, Arjen Y

    2014-03-01

    This study develops water footprint scenarios for 2050 based on a number of drivers of change: population growth, economic growth, production/trade pattern, consumption pattern (dietary change, bioenergy use) and technological development. The objective the study is to understand the changes in the water footprint (WF) of production and consumption for possible futures by region and to elaborate the main drivers of this change. In addition, we assess virtual water flows between the regions of the world to show dependencies of regions on water resources in other regions under different possible futures. We constructed four scenarios, along two axes, representing two key dimensions of uncertainty: globalization versus regional selfsufficiency, and economy-driven development versus development driven by social and environmental objectives. The study shows how different drivers will change the level of water consumption and pollution globally in 2050. The presented scenarios can form a basis for a further assessment of how humanity can mitigate future freshwater scarcity. We showed with this study that reducing humanity's water footprint to sustainable levels is possible even with increasing populations, provided that consumption patterns change. This study can help to guide corrective policies at both national and international levels, and to set priorities for the years ahead in order to achieve sustainable and equitable use of the world's fresh water resources. Copyright © 2013 Elsevier Ltd. All rights reserved.

  16. Effect of Global Postural Rehabilitation program on spatiotemporal gait parameters of parkinsonian patients: a three-dimensional motion analysis study.

    Science.gov (United States)

    Vitale, Carmine; Agosti, Valeria; Avella, Dario; Santangelo, Gabriella; Amboni, Marianna; Rucco, Rosaria; Barone, Paolo; Corato, Francesco; Sorrentino, Giuseppe

    2012-12-01

    The aim of the present study was to evaluate the effects of a Global Postural Rehabilitation (GPR) program on motor symptoms and gait parameters of patients with Parkinson's disease (PD) by means of three-dimensional motion analysis study. Ten subjects with clinical diagnosis of PD were enrolled (study group). Age-, sex- and disease duration-matched PD patients were recruited as a control group (no treatment). Three-dimensional motion analysis was conducted by means of a stereophotogrammetric system. After basal evaluation, the study group underwent a specific rehabilitation program consisting of individual 40 min GPR daily sessions, 3 days a week for 4 consecutive weeks. Neurological status and spatiotemporal gait parameters of the two groups were evaluated at study entry (t (0)), at 4 weeks (t (1), end of rehabilitation protocol) and at 8 and 12 weeks (t (2) and t (3), follow-up evaluation). At baseline evaluation, the two groups did not differ in clinical features and gait parameters. At the end of rehabilitation protocol (t (1)) and at follow-up evaluation (t (2) and t (3)), a significant improvement in temporal gait parameters and UPDRS scores was observed in all treated patients as compared to baseline and controls. Our preliminary findings showed that significant improvements in mobility and gait parameters of PD patients can be obtained through GPR treatment, with a parallel improvement in clinical status. Quantitative analysis of gait pattern can be considered a useful tool to assess the efficacy of rehabilitation interventions in patients affected by PD.

  17. Crystallization and preliminary X-ray diffraction analysis of L-threonine dehydrogenase (TDH) from the hyperthermophilic archaeon Thermococcus kodakaraensis.

    Science.gov (United States)

    Bowyer, A; Mikolajek, H; Wright, J N; Coker, A; Erskine, P T; Cooper, J B; Bashir, Q; Rashid, N; Jamil, F; Akhtar, M

    2008-09-01

    The enzyme L-threonine dehydrogenase catalyses the NAD(+)-dependent conversion of L-threonine to 2-amino-3-ketobutyrate, which is the first reaction of a two-step biochemical pathway involved in the metabolism of threonine to glycine. Here, the crystallization and preliminary crystallographic analysis of L-threonine dehydrogenase (Tk-TDH) from the hyperthermophilic organism Thermococcus kodakaraensis KOD1 is reported. This threonine dehydrogenase consists of 350 amino acids, with a molecular weight of 38 kDa, and was prepared using an Escherichia coli expression system. The purified native protein was crystallized using the hanging-drop vapour-diffusion method and crystals grew in the tetragonal space group P4(3)2(1)2, with unit-cell parameters a = b = 124.5, c = 271.1 A. Diffraction data were collected to 2.6 A resolution and preliminary analysis indicates that there are four molecules in the asymmetric unit of the crystal.

  18. Integration and global analysis of isothermal titration calorimetry data for studying macromolecular interactions.

    Science.gov (United States)

    Brautigam, Chad A; Zhao, Huaying; Vargas, Carolyn; Keller, Sandro; Schuck, Peter

    2016-05-01

    Isothermal titration calorimetry (ITC) is a powerful and widely used method to measure the energetics of macromolecular interactions by recording a thermogram of differential heating power during a titration. However, traditional ITC analysis is limited by stochastic thermogram noise and by the limited information content of a single titration experiment. Here we present a protocol for bias-free thermogram integration based on automated shape analysis of the injection peaks, followed by combination of isotherms from different calorimetric titration experiments into a global analysis, statistical analysis of binding parameters and graphical presentation of the results. This is performed using the integrated public-domain software packages NITPIC, SEDPHAT and GUSSI. The recently developed low-noise thermogram integration approach and global analysis allow for more precise parameter estimates and more reliable quantification of multisite and multicomponent cooperative and competitive interactions. Titration experiments typically take 1-2.5 h each, and global analysis usually takes 10-20 min.

  19. - and Syn-Eruptive Surface Movements of Azerbaijan Mud Volcanoes Detected Through Insar Analysis: Preliminary Results

    Science.gov (United States)

    Antonielli, Benedetta; Monserrat, Oriol; Bonini, Marco; Righini, Gaia; Sani, Federico; Luzi, Guido; Feyzullayev, Akper; Aliyev, Chingiz

    2014-05-01

    Mud volcanism is a process that consists in the extrusion of mud, fragments or blocks of country rocks, saline waters and gases, mostly methane. This mechanism is typically linked to in-depth hydrocarbon traps, and it builds up a variety of conical edifices with dimension and morphology similar to those of magmatic volcanoes. Interferometry by Satellite Aperture Radar (InSAR) techniques have been commonly used to monitor and investigate the ground deformation connected to the eruptive phases of magmatic volcanoes. InSAR techniques have also been employed to explore the ground deformation associated with the LUSI mud volcano in Java (Indonesia). We aim to carry out a study on the paroxysmal activities of the Azerbaijan mud volcanoes, among the largest on Earth, using similar techniques. In particular the deformations of the mud volcanic systems were analyzed through the technique of satellite differential interferometry (DInSAR), thanks to the acquisition of 16 descending and 4 ascending Envisat images, spanning about 4 years (October 2003-November 2007); these data were provided by the European Space Agency. The preliminary analysis of a set of 77 interferograms and the unwrapping process elaboration of some of them selected according to the best coherence values, allowed the detection of significant deformations in correspondence of Ayaz-Akhtarma and Khara Zira Island mud volcanoes. This analysis has allowed to identify relevant ground deformations of the volcanic systems in connection with the main eruptive events in 2005 and in 2006 respectively, that are recorded by the catalogue of Azerbaijan mud volcano eruptions until 2007. The preliminary analysis of the interferograms of the Ayaz-Akhtarma and the Khara Zira mud volcanoes shows that the whole volcano edifice or part of it is subject to a ground displacement before or in coincidence with the eruption. Assuming that the movement is mainly vertical, we suppose that deformation is due to bulging of the volcanic

  20. Flow cytometric analysis of oil palm: a preliminary analysis for cultivars and genomic DNA alteration

    Directory of Open Access Journals (Sweden)

    Warawut Chuthammathat

    2005-12-01

    Full Text Available DNA contents of oil palm (Elaeis guineensis Jacq. cultivars were analyzed by flow cytometry using different external reference plant species. Analysis using corn (Zea mays line CE-777 as a reference plant gave the highest DNA content of oil palm (4.72±0.23 pg 2C-1 whereas the DNA content was found to be lower when using soybean (Glycine max cv. Polanka (3.77±0.09 pg 2C-1 or tomato (Lycopersicon esculentum cv. Stupicke (4.25±0.09 pg 2C-1 as a reference. The nuclear DNA contents of Dura (D109, Pisifera (P168 and Tenera (T38 cultivars were 3.46±0.04, 3.24±0.03 and 3.76±0.04 pg 2C-1 nuclei, respectively, using soybean as a reference. One haploid genome of oil palm therefore ranged from 1.56 to 1.81±109 base pairs. DNA contents from one-year-old calli and cell suspension of oil palm were found to be significantly different from those of seedlings. It thus should be noted that genomic DNA alteration occurred in these cultured tissues. We therefore confirm that flow cytometric analysis could verify cultivars, DNA content and genomic DNA alteration of oil palm using soybean as an external reference standard.

  1. Applications of Photogrammetry for Analysis of Forest Plantations. Preliminary study: Analysis of individual trees

    Science.gov (United States)

    Mora, R.; Barahona, A.; Aguilar, H.

    2015-04-01

    This paper presents a method for using high detail volumetric information, captured with a land based photogrammetric survey, to obtain information from individual trees. Applying LIDAR analysis techniques it is possible to measure diameter at breast height, height at first branch (commercial height), basal area and volume of an individual tree. Given this information it is possible to calculate how much of that tree can be exploited as wood. The main objective is to develop a methodology for successfully surveying one individual tree, capturing every side of the stem a using high resolution digital camera and reference marks with GPS coordinates. The process is executed for several individuals of two species present in the metropolitan area in San Jose, Costa Rica, Delonix regia (Bojer) Raf. and Tabebuia rosea (Bertol.) DC., each one with different height, stem shape and crown area. Using a photogrammetry suite all the pictures are aligned, geo-referenced and a dense point cloud is generated with enough detail to perform the required measurements, as well as a solid tridimensional model for volume measurement. This research will open the way to develop a capture methodology with an airborne camera using close range UAVs. An airborne platform will make possible to capture every individual in a forest plantation, furthermore if the analysis techniques applied in this research are automated it will be possible to calculate with high precision the exploit potential of a forest plantation and improve its management.

  2. Effective Field Theory of Dark Matter: a Global Analysis

    CERN Document Server

    Liem, Sebastian; Calore, Francesca; de Austri, Roberto Ruiz; Tait, Tim M P; Trotta, Roberto; Weniger, Christoph

    2016-01-01

    We present global fits of an effective field theory description of real, and complex scalar dark matter candidates. We simultaneously take into account all possible dimension 6 operators consisting of dark matter bilinears and gauge invariant combinations of quark and gluon fields. We derive constraints on the free model parameters for both the real (five parameters) and complex (seven) scalar dark matter models obtained by combining Planck data on the cosmic microwave background, direct detection limits from LUX, and indirect detection limits from the Fermi Large Area Telescope. We find that for real scalars indirect dark matter searches disfavour a dark matter particle mass below 100 GeV. For the complex scalar dark matter particle current data have a limited impact due to the presence of operators that lead to p-wave annihilation, and also do not contribute to the spin-independent scattering cross- section. Although current data are not informative enough to strongly constrain the theory parameter space, w...

  3. Comparative Analysis of Dayside Reconnection Models in Global Magnetosphere Simulations

    CERN Document Server

    Komar, C M; Cassak, P A

    2015-01-01

    We test and compare a number of existing models predicting the location of magnetic reconnection at Earth's dayside magnetopause for various solar wind conditions. We employ robust image processing techniques to determine the locations where each model predicts reconnection to occur. The predictions are then compared to the magnetic separators, the magnetic field lines separating different magnetic topologies. The predictions are tested in distinct high-resolution simulations with interplanetary magnetic field (IMF) clock angles ranging from 30 to 165 degrees in global magnetohydrodynamic simulations using the three-dimensional Block-Adaptive Tree Solarwind Roe-type Upwind Scheme (BATS-R-US) code with a uniform resistivity, although the described techniques can be generally applied to any self-consistent magnetosphere code. Additional simulations are carried out to test location model dependence on IMF strength and dipole tilt. We find that most of the models match large portions of the magnetic separators wh...

  4. Preliminary palynological analysis of a Holocene peat bog from Apakará-tepui (Chimantá Massif, Venezuelan Guayana

    Directory of Open Access Journals (Sweden)

    Rull, V.

    2011-12-01

    Full Text Available Preliminary palynological analysis of a Holocene peat bog from Apakará-tepui (Chimantá Massif, Venezuelan Guayana.- This paper reports the preliminary palynological results, at a millennial scale, of a Holocene peat bog sequence, since around 8.0 cal kyr BP to the present, obtained in the summit of the Apakará-tepui (2170 m elevation, in the Chimantá massif, located in the neotropical Venezuelan Guayana. The early Holocene was characterized by a vegetation different to the present, in which trees and shrubs dominated and Myrica (Myricaceae was the main element of the gallery forests around a permanent water body, as indicated by the continuous presence of Isoëtes (Isoëtaceae in high percentages. Around the middle Holocene (5.3 cal kyr BP, a shift towards more herbaceous and non-flooded communities occurred, and the present day vegetation established. This has been interpreted as a shift from warmer and wetter climates to cooler and drier conditions. The first phase, from 8.0 to 5.3 cal kyr BP, falls within a warming phase widely documented worldwide, known as the Holocene Thermal Maximum. The millennial trends shown here will be refined with further studies at centennial to decadal time scales. These results support the hypothesis that the best sites to detect paleoenvironmental changes in the summits of the tabular Guayana mountains are close to altitudinal ecotones.

    Análisis palinológico preliminar de una turbera holocena del Apakará-tepui (Macizo de Chimantá, Guayana venezolana.- Este artículo presenta los resultados palinológicos preliminares, a escala de milenios, de una secuencia holocena, desde 8.0 cal kyr BP hasta la actualidad, obtenida en la cima del Apakará-tepui (2170 m de altitud, en el Macizo del Chimantá, situado en la región neotropical de la Guayana venezolana. El Holoceno temprano se caracterizó por una vegetación diferente a la actual, dominada por árboles y arbustos, en la que

  5. GLOBAL ANALYSIS OF KOI-977: SPECTROSCOPY, ASTEROSEISMOLOGY, AND PHASE-CURVE ANALYSIS

    Energy Technology Data Exchange (ETDEWEB)

    Hirano, Teruyuki; Sato, Bun' ei; Kobayashi, Atsushi [Department of Earth and Planetary Sciences, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8551 (Japan); Masuda, Kento [Department of Physics, The University of Tokyo, Tokyo 113-0033 (Japan); Benomar, Othman [Department of Astronomy, The University of Tokyo, Tokyo 113-0033 (Japan); Takeda, Yoichi; Omiya, Masashi; Harakawa, Hiroki, E-mail: hirano@geo.titech.ac.jp [National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan)

    2015-01-20

    We present a global analysis of KOI-977, one of the planet host candidates detected by Kepler. The Kepler Input Catalog (KIC) reports that KOI-977 is a red giant, for which few close-in planets have been discovered. Our global analysis involves spectroscopic and asteroseismic determinations of stellar parameters (e.g., mass and radius) and radial velocity (RV) measurements. Our analyses reveal that KOI-977 is indeed a red giant, possibly in the red clump, but its estimated radius (≳ 20 R {sub ☉} = 0.093 AU) is much larger than KOI-977.01's orbital distance (∼0.027 AU) estimated from its period (P {sub orb} ∼ 1.35 days) and host star's mass. RV measurements show a small variation, which also contradicts the amplitude of ellipsoidal variations seen in the light curve folded with KOI-977.01's period. Therefore, we conclude that KOI-977.01 is a false positive, meaning that the red giant, for which we measured the radius and RVs, is different from the object that produces the transit-like signal (i.e., an eclipsing binary). On the basis of this assumption, we also perform a light curve analysis including the modeling of transits/eclipses and phase-curve variations, adopting various values for the dilution factor D, which is defined as the flux ratio between the red giant and eclipsing binary. Fitting the whole folded light curve as well as individual transits in the short cadence data simultaneously, we find that the estimated mass and radius ratios of the eclipsing binary are consistent with those of a solar-type star and a late-type star (e.g., an M dwarf) for D ≳ 20.

  6. Preliminary risk analysis applied to the handling of health-care waste

    Directory of Open Access Journals (Sweden)

    Carvalho S.M.L.

    2002-01-01

    Full Text Available Between 75% and 90% of the waste produced by health-care providers no risk or is "general" health-care waste, comparable to domestic waste. The remaining 10-25% of health-care waste is regarded as hazardous due to one or more of the following characteristics: it may contain infectious agents, sharps, toxic or hazardous chemicals or it may be radioactive. Infectious health-care waste, particularly sharps, has been responsible for most of the accidents reported in the literature. In this work the preliminary risks analysis (PRA technique was used to evaluate practices in the handling of infectious health-care waste. Currently the PRA technique is being used to identify and to evaluate the potential for hazard of the activities, products, and services from facilities and industries. The system studied was a health-care establishment which has handling practices for infectious waste. Thirty-six procedures related to segregation, containment, internal collection, and storage operation were analyzed. The severity of the consequences of the failure (risk that can occur from careless management of infectious health-care waste was classified into four categories: negligible, marginal, critical, and catastrophic. The results obtained in this study showed that events with critics consequences, about 80%, may occur during the implementation of the containment operation, suggesting the need to prioritize this operation. As a result of the methodology applied in this work, a flowchart the risk series was also obtained. In the flowchart the events that can occur as a consequence of a improper handling of infectious health-care waste, which can cause critical risks such as injuries from sharps and contamination (infection from pathogenic microorganisms, are shown.

  7. Stochastic index model for intermittent regimes: from preliminary analysis to regionalisation

    Directory of Open Access Journals (Sweden)

    M. Rianna

    2011-04-01

    Full Text Available In small and medium-sized basins or in rivers characterized by intermittent discharges, with low or negligible/null observed values for long periods of the year, the correct representation of the discharge regime is important for issues related to water management and to define the amount and quality of water available for irrigation, domestic and recreational uses. In these cases, only one index as a statistical metric is often not enough; it is thus necessary to introduce Flow Duration Curves (FDC.

    The aim of this study is therefore to combine a stochastic index flow model capable of reproducing the FDC record period of a river, regardless of the persistence and seasonality of the series, with the theory of total probability in order to calculate how often a river is dry.

    The paper draws from preliminary analyses, including a study to estimate the correlation between discharge indicators Q95, Q50 and Q1 (discharges exceeding 95%, 50% or 1% of the time, respectively and some fundamental characteristics of the basin, as well as to identify homogeneous regions in the target area through the study of several geo-morphological features and climatic conditions. The stochastic model was then applied in one of the homogeneous regions that includes intermittent rivers.

    Finally, the model was regionalized by means of regression analysis in order to calculate the FDC for ungauged basins; the reliability of this method was tested using jack-knife validation.

  8. Identification of succinic semialdehyde reductases from Geobacter: expression,purification, crystallization, preliminary functional, and crystallographic analysis

    Institute of Scientific and Technical Information of China (English)

    Yanfeng Zhang; Xiaoli Gao; Yi Zheng; R. Michae; Garavito

    2011-01-01

    Succinic semialdehyde reductase (SSAR) is an important enzyme involved in γ-aminobutyrate (GABA) metabolism.By converting succinic semialdehyde (SSA) to γ-hydroxybutyrate (GHB),the SSAR facilitates an alternative pathway for GABA degradation.In this study,we identified SSARs from Geobacter sulfurreducens and Geobacter metallireducens (GsSSAR and GmSSAR,respectively).The enzymes were over-expressed in Escherichia coil and purified to near homogeneity.Both GsSSAR and GmSSAR showed the activity of reducing SSA using nicotinamide adenine dinucleotide phosphate as a co-factor.The oligomeric sizes of GsSSAR and GmSSAR,as determined by analytical size exclusion chromatography,suggest that the enzymes presumably exist as tetramers in solution.The recombinant GsSSAR and GmSSAR crystallized in the presence of NADP+,and the resulting crystals diffracted to 1.89 (A) (GsSSAR) and 2.25 (A)(GmSSAR) resolution.The GsSSAR and GmSSAR crystals belong to the space groups P21221 (a =99.61 (A),b =147.49 (A),c =182.47 A) and P1 (a =75.97 (A) b =79.14 (A) c =95.47 (A),α =82.15°,β =88.80°,γ=87.66°),respectively.Preliminary crystallographic data analysis suggests the presence of eight protein monomers in the asymmetric units for both GsSSAR and GmSSAR.

  9. Identification of succinic semialdehyde reductases from Geobacter: expression, purification, crystallization, preliminary functional, and crystallographic analysis

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Yanfeng; Gao, Xiaoli; Zheng, Yi; Garavito, R. Michael (MSU)

    2012-04-30

    Succinic semialdehyde reductase (SSAR) is an important enzyme involved in {gamma}-aminobutyrate (GABA) metabolism. By converting succinic semialdehyde (SSA) to {gamma}-hydroxybutyrate (GHB), the SSAR facilitates an alternative pathway for GABA degradation. In this study, we identified SSARs from Geobacter sulfurreducens and Geobacter metallireducens (GsSSAR and GmSSAR, respectively). The enzymes were over-expressed in Escherichia coli and purified to near homogeneity. Both GsSSAR and GmSSAR showed the activity of reducing SSA using nicotinamide adenine dinucleotide phosphate as a co-factor. The oligomeric sizes of GsSSAR and GmSSAR, as determined by analytical size exclusion chromatography, suggest that the enzymes presumably exist as tetramers in solution. The recombinant GsSSAR and GmSSAR crystallized in the presence of NADP{sup +}, and the resulting crystals diffracted to 1.89 {angstrom} (GsSSAR) and 2.25 {angstrom} (GmSSAR) resolution. The GsSSAR and GmSSAR crystals belong to the space groups P2{sub 1}22{sub 1} (a = 99.61 {angstrom}, b = 147.49 {angstrom}, c = 182.47 {angstrom}) and P1 (a = 75.97 {angstrom}, b = 79.14 {angstrom}, c = 95.47 {angstrom}, {alpha} = 82.15{sup o}, {beta} = 88.80{sup o}, {gamma} = 87.66{sup o}), respectively. Preliminary crystallographic data analysis suggests the presence of eight protein monomers in the asymmetric units for both GsSSAR and GmSSAR.

  10. Preliminary Analysis of the Transient Reactor Test Facility (TREAT) with PROTEUS

    Energy Technology Data Exchange (ETDEWEB)

    Connaway, H. M. [Argonne National Lab. (ANL), Argonne, IL (United States); Lee, C. H. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2015-11-30

    The neutron transport code PROTEUS has been used to perform preliminary simulations of the Transient Reactor Test Facility (TREAT). TREAT is an experimental reactor designed for the testing of nuclear fuels and other materials under transient conditions. It operated from 1959 to 1994, when it was placed on non-operational standby. The restart of TREAT to support the U.S. Department of Energy’s resumption of transient testing is currently underway. Both single assembly and assembly-homogenized full core models have been evaluated. Simulations were performed using a historic set of WIMS-ANL-generated cross-sections as well as a new set of Serpent-generated cross-sections. To support this work, further analyses were also performed using additional codes in order to investigate particular aspects of TREAT modeling. DIF3D and the Monte-Carlo codes MCNP and Serpent were utilized in these studies. MCNP and Serpent were used to evaluate the effect of geometry homogenization on the simulation results and to support code-to-code comparisons. New meshes for the PROTEUS simulations were created using the CUBIT toolkit, with additional meshes generated via conversion of selected DIF3D models to support code-to-code verifications. All current analyses have focused on code-to-code verifications, with additional verification and validation studies planned. The analysis of TREAT with PROTEUS-SN is an ongoing project. This report documents the studies that have been performed thus far, and highlights key challenges to address in future work.

  11. Purification, crystallization and preliminary structural analysis of nucleoside diphosphate kinase from Bacillus anthracis

    Energy Technology Data Exchange (ETDEWEB)

    Misra, Gauri [Molecular and Structural Biology Division, Central Drug Research Institute, PO Box 173, Chattar Manzil, Mahatma Gandhi Marg, Lucknow 226 001 (India); Aggarwal, Anita [Institute of Genomics and Integrative Biology, Mall Road, Delhi 110 007 (India); Mittal, Sonia [Molecular and Structural Biology Division, Central Drug Research Institute, PO Box 173, Chattar Manzil, Mahatma Gandhi Marg, Lucknow 226 001 (India); Singh, Yogendra [Institute of Genomics and Integrative Biology, Mall Road, Delhi 110 007 (India); Ramachandran, Ravishankar, E-mail: r-ravishankar@cdri.res.in [Molecular and Structural Biology Division, Central Drug Research Institute, PO Box 173, Chattar Manzil, Mahatma Gandhi Marg, Lucknow 226 001 (India)

    2007-12-01

    Nucleoside diphosphate kinase from B. anthracis has been crystallized. Preliminary crystallographic analysis shows that there is one monomer in the asymmetric unit of the crystal. Bacillus anthracis nucleoside diphosphate kinase (BaNdk) is an enzyme whose primary function is to maintain deoxynucleotide triphosphate (dNTP) pools by converting deoxynucleotide diphosphates to triphosphates using ATP as the major phosphate donor. Although the structures of Ndks from a variety of organisms have been elucidated, the enzyme from sporulating bacteria has not been structurally characterized to date. Crystals of the B. anthracis enzyme were grown using the vapour-diffusion method from a hanging drop consisting of 2 µl 10 mg ml{sup −1} protein in 50 mM Tris–HCl pH 8.0, 50 mM NaCl, 5 mM EDTA equilibrated against 500 µl reservoir solution consisting of 2.25 M ammonium formate and 0.1 M HEPES buffer pH 7.25. Diffraction data extending to 2.0 Å were collected at room temperature from a single crystal with unit-cell parameters a = b = 107.53, c = 52.3 Å. The crystals are hexagonal in shape and belong to space group P6{sub 3}22. The crystals contain a monomer in the asymmetric unit, which corresponds to a Matthews coefficient (V{sub M}) of 2.1 Å{sup 3} Da{sup −1} and a solvent content of about 36.9%.

  12. A new scoring system in Cystic Fibrosis: statistical tools for database analysis - a preliminary report.

    Science.gov (United States)

    Hafen, G M; Hurst, C; Yearwood, J; Smith, J; Dzalilov, Z; Robinson, P J

    2008-10-05

    Cystic fibrosis is the most common fatal genetic disorder in the Caucasian population. Scoring systems for assessment of Cystic fibrosis disease severity have been used for almost 50 years, without being adapted to the milder phenotype of the disease in the 21st century. The aim of this current project is to develop a new scoring system using a database and employing various statistical tools. This study protocol reports the development of the statistical tools in order to create such a scoring system. The evaluation is based on the Cystic Fibrosis database from the cohort at the Royal Children's Hospital in Melbourne. Initially, unsupervised clustering of the all data records was performed using a range of clustering algorithms. In particular incremental clustering algorithms were used. The clusters obtained were characterised using rules from decision trees and the results examined by clinicians. In order to obtain a clearer definition of classes expert opinion of each individual's clinical severity was sought. After data preparation including expert-opinion of an individual's clinical severity on a 3 point-scale (mild, moderate and severe disease), two multivariate techniques were used throughout the analysis to establish a method that would have a better success in feature selection and model derivation: 'Canonical Analysis of Principal Coordinates' and 'Linear Discriminant Analysis'. A 3-step procedure was performed with (1) selection of features, (2) extracting 5 severity classes out of a 3 severity class as defined per expert-opinion and (3) establishment of calibration datasets. (1) Feature selection: CAP has a more effective "modelling" focus than DA.(2) Extraction of 5 severity classes: after variables were identified as important in discriminating contiguous CF severity groups on the 3-point scale as mild/moderate and moderate/severe, Discriminant Function (DF) was used to determine the new groups mild, intermediate moderate, moderate, intermediate

  13. A new scoring system in Cystic Fibrosis: statistical tools for database analysis – a preliminary report

    Science.gov (United States)

    Hafen, GM; Hurst, C; Yearwood, J; Smith, J; Dzalilov, Z; Robinson, PJ

    2008-01-01

    Background Cystic fibrosis is the most common fatal genetic disorder in the Caucasian population. Scoring systems for assessment of Cystic fibrosis disease severity have been used for almost 50 years, without being adapted to the milder phenotype of the disease in the 21st century. The aim of this current project is to develop a new scoring system using a database and employing various statistical tools. This study protocol reports the development of the statistical tools in order to create such a scoring system. Methods The evaluation is based on the Cystic Fibrosis database from the cohort at the Royal Children's Hospital in Melbourne. Initially, unsupervised clustering of the all data records was performed using a range of clustering algorithms. In particular incremental clustering algorithms were used. The clusters obtained were characterised using rules from decision trees and the results examined by clinicians. In order to obtain a clearer definition of classes expert opinion of each individual's clinical severity was sought. After data preparation including expert-opinion of an individual's clinical severity on a 3 point-scale (mild, moderate and severe disease), two multivariate techniques were used throughout the analysis to establish a method that would have a better success in feature selection and model derivation: 'Canonical Analysis of Principal Coordinates' and 'Linear Discriminant Analysis'. A 3-step procedure was performed with (1) selection of features, (2) extracting 5 severity classes out of a 3 severity class as defined per expert-opinion and (3) establishment of calibration datasets. Results (1) Feature selection: CAP has a more effective "modelling" focus than DA. (2) Extraction of 5 severity classes: after variables were identified as important in discriminating contiguous CF severity groups on the 3-point scale as mild/moderate and moderate/severe, Discriminant Function (DF) was used to determine the new groups mild, intermediate moderate

  14. A new scoring system in Cystic Fibrosis: statistical tools for database analysis – a preliminary report

    Directory of Open Access Journals (Sweden)

    Yearwood J

    2008-10-01

    Full Text Available Abstract Background Cystic fibrosis is the most common fatal genetic disorder in the Caucasian population. Scoring systems for assessment of Cystic fibrosis disease severity have been used for almost 50 years, without being adapted to the milder phenotype of the disease in the 21st century. The aim of this current project is to develop a new scoring system using a database and employing various statistical tools. This study protocol reports the development of the statistical tools in order to create such a scoring system. Methods The evaluation is based on the Cystic Fibrosis database from the cohort at the Royal Children's Hospital in Melbourne. Initially, unsupervised clustering of the all data records was performed using a range of clustering algorithms. In particular incremental clustering algorithms were used. The clusters obtained were characterised using rules from decision trees and the results examined by clinicians. In order to obtain a clearer definition of classes expert opinion of each individual's clinical severity was sought. After data preparation including expert-opinion of an individual's clinical severity on a 3 point-scale (mild, moderate and severe disease, two multivariate techniques were used throughout the analysis to establish a method that would have a better success in feature selection and model derivation: 'Canonical Analysis of Principal Coordinates' and 'Linear Discriminant Analysis'. A 3-step procedure was performed with (1 selection of features, (2 extracting 5 severity classes out of a 3 severity class as defined per expert-opinion and (3 establishment of calibration datasets. Results (1 Feature selection: CAP has a more effective "modelling" focus than DA. (2 Extraction of 5 severity classes: after variables were identified as important in discriminating contiguous CF severity groups on the 3-point scale as mild/moderate and moderate/severe, Discriminant Function (DF was used to determine the new groups mild

  15. Improving Department of Defense Global Distribution Performance Through Network Analysis

    Science.gov (United States)

    2016-06-01

    consideration given the origin. The new method includes the origin information. Using parametric and non- parametric statistical tests and data analysis...Using parametric and non- parametric statistical tests and data analysis techniques, we show that the addition of requisition origin information...apply a weighting scale to those elements. Kunadhamrak and Hanaoka constructed a multi-criteria metric using a combination of a fuzzy- 12

  16. SINGLE-SHELL TANK INTEGRITY PROJECT ANALYSIS OF RECORD-PRELIMINARY MODELING PLAN FOR THERMAL AND OPERATING LOADS

    Energy Technology Data Exchange (ETDEWEB)

    RAST RS; RINKER MW; BAPANAALLI SK; DEIBLER JE; GUZMAN-LEONG CE; JOHNSON KI; KARRI NK; PILLI SP; SANBORN SE

    2010-10-22

    This document is a Phase I deliverable for the Single-Shell Tank Analysis of Record effort. This document is not the Analysis of Record. The intent of this document is to guide the Phase II detailed modeling effort. Preliminary finite element models for each of the tank types were developed and different case studies were performed on one or more of these tank types. Case studies evaluated include thermal loading, waste level variation, the sensitivity of boundary effects (soil radial extent), excavation slope or run to rise ratio, soil stratigraphic (property and layer thickness) variation at different farm locations, and concrete material property variation and their degradation under thermal loads. The preliminary analysis document reviews and preliminary modeling analysis results are reported herein. In addition, this report provides recommendations for the next phase of the SST AOR project, SST detailed modeling. Efforts and results discussed in this report do not include seismic modeling as seismic modeling is covered by a separate report. The combined results of both static and seismic models are required to complete this effort. The SST AOR project supports the US Department of Energy's (DOE) Office of River Protection (ORP) mission for obtaining a better understanding of the structural integrity of Hanford's SSTs. The 149 SSTs, with six different geometries, have experienced a range of operating histories which would require a large number of unique analyses to fully characterize their individual structural integrity. Preliminary modeling evaluations were conducted to determine the number of analyses required for adequate bounding of each of the SST tank types in the Detailed Modeling Phase of the SST AOR Project. The preliminary modeling was conducted in conjunction with the Evaluation Criteria report, Johnson et al. (2010). Reviews of existing documents were conducted at the initial stage of preliminary modeling. These reviews guided the topics

  17. Analysis of global multiscale finite element methods for wave equations with continuum spatial scales

    KAUST Repository

    Jiang, Lijian

    2010-08-01

    In this paper, we discuss a numerical multiscale approach for solving wave equations with heterogeneous coefficients. Our interest comes from geophysics applications and we assume that there is no scale separation with respect to spatial variables. To obtain the solution of these multiscale problems on a coarse grid, we compute global fields such that the solution smoothly depends on these fields. We present a Galerkin multiscale finite element method using the global information and provide a convergence analysis when applied to solve the wave equations. We investigate the relation between the smoothness of the global fields and convergence rates of the global Galerkin multiscale finite element method for the wave equations. Numerical examples demonstrate that the use of global information renders better accuracy for wave equations with heterogeneous coefficients than the local multiscale finite element method. © 2010 IMACS.

  18. How do Organizational Learning and Market Conditions Affect the Relationship between Entrepreneurial Orientation and Firm Growth? A Preliminary Analysis on Small and Medium Size Hotels in Peninsular Malaysia

    National Research Council Canada - National Science Library

    Azilah Kasim; Levent Altinay

    2016-01-01

      This is a preliminary analysis on the influence of organizational learning and market conditions on the relationships between entrepreneurial orientation and growth of small and medium size hotels...

  19. Economic-Social Analysis of Global Illicit Drug Trade

    Directory of Open Access Journals (Sweden)

    Salahedin Ghaderi

    2003-11-01

    Full Text Available Political unstability, less respect to the role of law, low life standards and suitable conditions for poppy/coca cultivation, have all affected on growing illicit drug international trafficking. Colombia is the center for global cocaine industry. Colombians had to use ship in the Carribean but now they pass Mexico where the costs are half of using ship. Mexican traffickers permit that the domestic poppy plants turned into herion, Colombian cocaine transited to USA and methamephtamine manufactured and distributed. Golden triangle in southeast Asia is one of the major regions for opium poppy cultivation. This region has seen many guerrilla warfare for selling illicit drugs especially in Myanmar. Manufactured hroin is usually dealt in Thailand. Golden Crescent region in southwest Asia has a suitable climate for opium poppy cultivation which provides necessay money for purchasing needed weapons by rival groups in northwestern border provinces of Afghanistan and Pakistan. Nigeria is one of the main centers for transporting heroin from Golden Crescent and cocaine from Brazil. Dominics run cocaine trade in New York and New England and Afro-American criminal organizations conduct heroin trading in big cities such as New york, Detroit, Chicago, Phila Delphia and Washington. Street trading of illicit drugs is mainly done by cultural or commanding gangs. Illicit drug traffickers apply many methods to laundering their profits including money exchange, smurfs, electronic transferring, and faced firms (the firms that are only registered.

  20. Analysis of pathfinder SST algorithm for global and regional conditions

    Indian Academy of Sciences (India)

    Ajoy Kumar; P Minnett; G Podesta; R Evans; K Kilpatrick

    2000-12-01

    As part of the Pathfinder program developed jointly by National Aeronautics and Space Administration (NASA) and National Oceanic and Atmospheric Administration (NOAA) a large database of in situ sea surface temperature (SST) measurements coincident with satellite data is now available to the user community. The Pathfinder Matchup Database (PMDB) is a multi-year, multi-satellite collection of coincident measurements from the Advanced Very High Resolution Radiometer (AVHRR) and broadly distributed buoy data (matchups). This database allows the user community to test and validate new SST algorithms to improve the present accuracy of surface temperature measurements from satellites. In this paper we investigate the performance of a global Pathfinder algorithm to specific regional conditions. It is shown that for zenith angles less than 45°, the best-expected statistical discrepancy between satellite and buoy data is about ∼0.5 K. In general, the bias of the residuals (satellite - buoy) is negative in most regions, except in the North Atlantic and adjacent seas, where the residuals are always positive. A seasonal signal in SST residuals is observed in all regions and is strongest in the Indian Ocean. The channel-difference term used as a proxy for atmospheric water vapor correction is observed to be unresponsive for columnar water vapor values greater than 45 mm and high zenith angles. This unresponsiveness of the channels leads to underestimation of sea surface temperature from satellites in these conditions.

  1. Global horizontal irradiance clear sky models : implementation and analysis.

    Energy Technology Data Exchange (ETDEWEB)

    Stein, Joshua S.; Hansen, Clifford W.; Reno, Matthew J.

    2012-03-01

    Clear sky models estimate the terrestrial solar radiation under a cloudless sky as a function of the solar elevation angle, site altitude, aerosol concentration, water vapor, and various atmospheric conditions. This report provides an overview of a number of global horizontal irradiance (GHI) clear sky models from very simple to complex. Validation of clear-sky models requires comparison of model results to measured irradiance during clear-sky periods. To facilitate validation, we present a new algorithm for automatically identifying clear-sky periods in a time series of GHI measurements. We evaluate the performance of selected clear-sky models using measured data from 30 different sites, totaling about 300 site-years of data. We analyze the variation of these errors across time and location. In terms of error averaged over all locations and times, we found that complex models that correctly account for all the atmospheric parameters are slightly more accurate than other models, but, primarily at low elevations, comparable accuracy can be obtained from some simpler models. However, simpler models often exhibit errors that vary with time of day and season, whereas the errors for complex models vary less over time.

  2. Multisteps Global Kinetic Analysis of MSW Slow Pyrolysis

    Directory of Open Access Journals (Sweden)

    Dwi Aries Himawanto

    2013-12-01

    Full Text Available The goal of this research is to find relationships between single components slow pyrolysis characteristics and mixed component slow pyrolysis characteristics of segregated municipal solid wastes (MSW. The material of this research consists of organic wastes (bamboo wastes and banana leaves wastes and inorganic wastes (styrofoam wastes and snack wrapping wastes. The materials which used to study were the unprosessing waste. The samples were collected, dried and crushed until passing 20 mesh shieves then characterized in self manufactured macro balance. The thermogravimetry analyses were done to find the MSW slow pyrolysis characteristics. The 20 gram sample was placed in the furnace whose temperature is increased with 10 0C/min heating rate until reached 400 0 final temperature and held for 30 minutes before the sample is cooled into room temperature. One hundred ml/min nitrogen introduced from the bottom of furnace as a swept gas. The results of the research show that the global kinetic method could be used to predict the MSW single component activation energy but it should be modified to calculate the mixed sample activation energy . The predictive activation energy values which calculated based on weighed sum of single component have 18.5 % deviations if compared with experimental result.

  3. Global analysis on slope stability and its engineering application

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    In hydraulic engineering, sometimes it is necessary to consider the stability of sliding bodies with lateral frictional boundaries. Neither the existing three dimensional limit equilibrium methods nor the commercial software products are able to treat such situations. The three dimensional factor of safety is accordingly underestimated; while the shearing strength based on the three dimensional back analysis is overestimated. In this study, the lateral boundaries are regarded as the part of the slip surface. Based on the expression of the normal pressure on the slip surface and the patch interpolation, a rigorous solution for the three dimensional limit equilibrium analysis is realized. Meanwhile, the proposed procedure is applied to the stability analysis of the slope with a cable platform on the right bank in Da Gang Shan hydraulic project under construction.

  4. Global Interactions Analysis of Epileptic ECoG Data

    Science.gov (United States)

    Ortega, Guillermo J.; Sola, Rafael G.; Pastor, Jesús

    2007-05-01

    Localization of the epileptogenic zone is an important issue in epileptology, even though there is not a unique definition of the epileptic focus. The objective of the present study is to test ultrametric analysis to uncover cortical interactions in human epileptic data. Correlation analysis has been carried out over intraoperative Electro-Corticography (ECoG) data in 2 patients suffering from temporal lobe epilepsy (TLE). Recordings were obtained using a grid of 20 electrodes (5×4) covering the lateral temporal lobe and a strip of either 4 or 8 electrodes at the mesial temporal lobe. Ultrametric analysis was performed in the averaged final correlation matrices. By using the matrix of linear correlation coefficients and the appropriate metric distance between pairs of electrodes time series, we were able to construct Minimum Spanning Trees (MST). The topological connectivity displayed by these trees gives useful and valuable information regarding physiological and pathological information in the temporal lobe of epileptic patients.

  5. Analysis of rainfall-induced shallow landslides in Jamne and Jaszcze stream valleys (Polish Carpathians – preliminary results

    Directory of Open Access Journals (Sweden)

    Zydroń Tymoteusz

    2016-03-01

    Full Text Available Analysis of rainfall-induced shallow landslides in Jamne and Jaszcze stream valleys (Polish Carpathians - preliminary results. Preliminary shallow landslide susceptibility mapping of the Jamne and Jaszcze stream valleys, located in the Polish Flysch Carpathians, is presented in the paper. For the purpose of mapping, there were used SINMAP and Iverson’s models integrating infiltration and slope stability calculations. The calibration of the used models parameters, obtained from limited field and laboratory tests, was performed using data from 8-9 July 1997, when as a consequence of a very intense rainfall, 94 shallow landslides were observed on meadows and arable lands. A comparison of the slope stability calculation results and the localisation of the noticed shallow landslides showed satisfactory agreement between localisation of the observed and computed unstable areas. However, it was concluded that better simulation results were obtained using Iverson’s model.

  6. Analysis of the operation of a diffraction-radiation generator with preliminary HF modulation

    Science.gov (United States)

    Pivovarova, A. G.

    1991-05-01

    The excitation conditions and output characteristics of a diffraction-radiation generator with preliminary HF modulation are determined. Attention is given to the effects of the modulation parameter, the phase shift, and the aiming distance on the displacement of the generation zone, variations of the minimum starting current, the frequency shift, the oscillation amplitude, and the efficiency of the generator. It is shown that the efficiency of a generator with preliminary HF modulation can be twice as high as that of a generator without modulation.

  7. Preliminary analysis of mortality associated with rituximab use in autoimmune diseases.

    Science.gov (United States)

    Shetty, Shawn; Ahmed, A R

    2013-12-01

    Normal antibodies and pathogenic autoantibodies are produced by B-cells and plasma cells. Rituximab is a chimeric monoclonal antibody that targets the CD20 molecule on cells that express them on their surface and kills them. Rituximab has been increasingly used to treat several autoimmune diseases. Studies on fatal outcomes associated with rituximab therapy are lacking. A comprehensive and detailed analysis in which the multiple factors that could contribute to a fatal outcome in all the autoimmune diseases in which rituximab has been used would be cumbersome, lack uniformity and would prove difficult in making certain definitive conclusions and comparisons, but more importantly it would not allow to provide specific precautions and recommendations to prevent mortality. Hence, autoimmune mucocutaneous blistering diseases (AMBD) were used as model to study fatal outcomes in patients treated with rituximab between 2000 and 2013, using uniform 13 criteria. Fatal outcomes were found in 14 patients with autoimmune blistering diseases out of 134 patients (10.4%). Patients died due to infections (75%), gastrointestinal (17%) and cardiac events (8%). Causes of death were reported in 101 patients with other autoimmune diseases out of 4320 with a mortality rate of 2.4%. Among them, 44 patients (43.6%) died from infections. A statistical analysis of the data demonstrated that a statistically significant higher mortality rate was observed in patients with AMBD compared to patients with other autoimmune diseases. Similarly, a statistically significant higher rate of death due to infections was reported in patients with AMBD compared to patients with other autoimmune diseases. Use of systemic corticosteroids and immunosuppressive agents as concomitant therapy with rituximab enhanced immunosuppression. In many patients, B-cells were depleted for prolonged periods, even after clinical recovery was observed. Although its main action is depletion of B-cells, rituximab has a

  8. Global surface temperature change analysis based on MODIS data in recent twelve years

    Science.gov (United States)

    Mao, K. B.; Ma, Y.; Tan, X. L.; Shen, X. Y.; Liu, G.; Li, Z. L.; Chen, J. M.; Xia, L.

    2017-01-01

    Global surface temperature change is one of the most important aspects in global climate change research. In this study, in order to overcome shortcomings of traditional observation methods in meteorology, a new method is proposed to calculate global mean surface temperature based on remote sensing data. We found that (1) the global mean surface temperature was close to 14.35 °C from 2001 to 2012, and the warmest and coldest surface temperatures of the global in the recent twelve years occurred in 2005 and 2008, respectively; (2) the warmest and coldest surface temperatures on the global land surface occurred in 2005 and 2001, respectively, and on the global ocean surface in 2010 and 2008, respectively; and (3) in recent twelve years, although most regions (especially the Southern Hemisphere) are warming, global warming is yet controversial because it is cooling in the central and eastern regions of Pacific Ocean, northern regions of the Atlantic Ocean, northern regions of China, Mongolia, southern regions of Russia, western regions of Canada and America, the eastern and northern regions of Australia, and the southern tip of Africa. The analysis of daily and seasonal temperature change indicates that the temperature change is mainly caused by the variation of orbit of celestial body. A big data model based on orbit position and gravitational-magmatic change of celestial body with the solar or the galactic system should be built and taken into account for climate and ecosystems change at a large spatial-temporal scale.

  9. Preliminary Analysis of Ground-based Orbit Determination Accuracy for the Wide Field Infrared Survey Telescope (WFIRST)

    Science.gov (United States)

    Sease, Brad

    2017-01-01

    The Wide Field Infrared Survey Telescope is a 2.4-meter telescope planned for launch to the Sun-Earth L2 point in 2026. This paper details a preliminary study of the achievable accuracy for WFIRST from ground-based orbit determination routines. The analysis here is divided into two segments. First, a linear covariance analysis of early mission and routine operations provides an estimate of the tracking schedule required to meet mission requirements. Second, a simulated operations scenario gives insight into the expected behavior of a daily Extended Kalman Filter orbit estimate over the first mission year given a variety of potential momentum unloading schemes.

  10. Waterpipe tobacco smoking legislation and policy enactment: a global analysis.

    Science.gov (United States)

    Jawad, Mohammed; El Kadi, Lama; Mugharbil, Sanaa; Nakkash, Rima

    2015-03-01

    (1) To review how current global tobacco control policies address regulation of waterpipe tobacco smoking (WTS). (2) To identify features associated with enactment and enforcement of WTS legislation. (1) Legislations compiled by Tobacco Control Laws (www.tobaccocontrollaws.org). (2) Weekly news articles by 'Google Alerts' (www.google.com/alerts) from July 2013 to August 2014. (1) Countries containing legislative reviews, written by legal experts, were included. Countries prohibiting tobacco sales were excluded. (2) News articles discussing aspects of the WHO FCTC were included. News articles related to electronic-waterpipe, crime, smuggling, opinion pieces or brief mentions of WTS were excluded. (1) Two reviewers independently abstracted the definition of "tobacco product" and/or "smoking". Four tobacco control domains (smokefree law, misleading descriptors, health warning labels and advertising/promotion/sponsorship) were assigned one of four categories based on the degree to which WTS had specific legislation. (2) Two investigators independently assigned at least one theme and associated subtheme to each news article. (1) Reviewed legislations of 62 countries showed that most do not address WTS regulation but instead rely on generic tobacco/smoking definitions to cover all tobacco products. Where WTS was specifically addressed, no additional legislative guidance accounted for the unique way it is smoked, except for in one country specifying health warnings on waterpipe apparatuses (2) News articles mainly reported on noncompliance with public smoking bans, especially in India, Pakistan and the UK. A regulatory framework evaluated for effectiveness and tailored for the specificities of WTS needs to be developed. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  11. Analysis of a global database containing tritium in precipitation

    Energy Technology Data Exchange (ETDEWEB)

    Buckley, R. L. [Savannah River Site (SRS), Aiken, SC (United States); Rabun, R. L. [Savannah River Site (SRS), Aiken, SC (United States); Heath, M. [Savannah River Site (SRS), Aiken, SC (United States)

    2016-02-17

    The International Atomic Energy Agency (IAEA) directed the collection of tritium in water samples from the mid-1950s to 2009. The Global Network of Isotopes in Precipitation (GNIP) data examined the airborne movement of isotope releases to the environment, with an objective of collecting spatial data on the isotope content of precipitation across the globe. The initial motivation was to monitor atmospheric thermonuclear test fallout through tritium, deuterium, and oxygen isotope concentrations, but after the 1970s the focus changed to being an observation network of stable hydrogen and oxygen isotope data for hydrologic studies. The GNIP database provides a wealth of tritium data collections over a long period of time. The work performed here primarily examined data features in the past 30 years (after much of the effects of above-ground nuclear testing in the late 1950s to early 1960s decayed away), revealing potentially unknown tritium sources. The available data at GNIP were reorganized to allow for evaluation of trends in the data both temporally and spatially. Several interesting cases were revealed, including relatively high measured concentrations in the Atlantic and Indian Oceans, Russia, Norway, as well as an increase in background concentration at a collector in South Korea after 2004. Recent data from stations in the southeastern United States nearest to the Savannah River Site do not indicate any high values. Meteorological impacts have not been considered in this study. Further research to assess the likely source location of interesting cases using transport simulations and/or literature searches is warranted.

  12. Analysis of global sumoylation changes occurring during keratinocyte differentiation.

    Directory of Open Access Journals (Sweden)

    Phillip R Heaton

    Full Text Available Sumoylation is a highly dynamic process that plays a role in a multitude of processes ranging from cell cycle progression to mRNA processing and cancer. A previous study from our lab demonstrated that SUMO plays an important role in keratinocyte differentiation. Here we present a new method of tracking the sumoylation state of proteins by creating a stably transfected HaCaT keratinocyte cell line expressing an inducible SNAP-SUMO3 protein. The SNAP-tag allows covalent fluorescent labeling that is denaturation resistant. When combined with two-dimensional gel electrophoresis, the SNAP-tag technology provides direct visualization of sumoylated targets and can be used to follow temporal changes in the global cohort of sumoylated proteins during dynamic processes such as differentiation. HaCaT keratinocyte cells expressing SNAP-SUMO3 displayed normal morphological and biochemical features that are consistent with typical keratinocyte differentiation. SNAP-SUMO3 also localized normally in these cells with a predominantly nuclear signal and some minor cytoplasmic staining, consistent with previous reports for untagged SUMO2/3. During keratinocyte differentiation the total number of proteins modified by SNAP-SUMO3 was highest in basal cells, decreased abruptly after induction of differentiation, and slowly rebounded beginning between 48 and 72 hours as differentiation progressed. However, within this overall trend the pattern of change for individual sumoylated proteins was highly variable with both increases and decreases in amount over time. From these results we conclude that sumoylation of proteins during keratinocyte differentiation is a complex process which likely reflects and contributes to the biochemical changes that drive differentiation.

  13. Effective field theory of dark matter: a global analysis

    Science.gov (United States)

    Liem, Sebastian; Bertone, Gianfranco; Calore, Francesca; de Austri, Roberto Ruiz; Tait, Tim M. P.; Trotta, Roberto; Weniger, Christoph

    2016-09-01

    We present global fits of an effective field theory description of real, and complex scalar dark matter candidates. We simultaneously take into account all possible dimension 6 operators consisting of dark matter bilinears and gauge invariant combinations of quark and gluon fields. We derive constraints on the free model parameters for both the real (five parameters) and complex (seven) scalar dark matter models obtained by combining Planck data on the cosmic microwave background, direct detection limits from LUX, and indirect detection limits from the Fermi Large Area Telescope. We find that for real scalars indirect dark matter searches disfavour a dark matter particle mass below 100 GeV. For the complex scalar dark matter particle current data have a limited impact due to the presence of operators that lead to p-wave annihilation, and also do not contribute to the spin-independent scattering cross-section. Although current data are not informative enough to strongly constrain the theory parameter space, we demonstrate the power of our formalism to reconstruct the theoretical parameters compatible with an actual dark matter detection, by assuming that the excess of gamma rays observed by the Fermi Large Area Telescope towards the Galactic centre is entirely due to dark matter annihilations. Please note that the excess can very well be due to astrophysical sources such as millisecond pulsars. We find that scalar dark matter interacting via effective field theory operators can in principle explain the Galactic centre excess, but that such interpretation is in strong tension with the non-detection of gamma rays from dwarf galaxies in the real scalar case. In the complex scalar case there is enough freedom to relieve the tension.

  14. Analysis and Improvement of TCP Congestion Control Mechanism Based on Global Optimization Model

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Network flow control is formulated as a global optimization problem of user profit. A general global optimization flow control model is established. This model combined with the stochastic model of TCP is used to study the global rate allocation characteristic of TCP. Analysis shows when active queue manage ment is used in network TCP rates tend to be allocated to maximize the aggregate of a user utility function Us (called Us fairness). The TCP throughput formula is derived. An improved TCP congestion control mecha nism is proposed. Simulations show its throughput is TCP friendly when competing with existing TCP and its rate change is smoother. Therefore, it is suitable to carry multimedia applications.

  15. Life history of the Harlequin ladybird, Harmonia axyridis; a global meta-analysis

    NARCIS (Netherlands)

    Raak-van den Berg, C.L.; Hemerik, A.; Werf, van der W.; Jong, de P.W.; Lenteren, van J.C.

    2017-01-01

    Data collected en used for a meta analysis on life history data of H. axyridis. And the resulting 20 best models for each life history characteristic. Published in the paper: Life history of the Harlequin ladybird, Harmonia axyridis; a global meta-analysis.

  16. Modeling and Analysis of Global and Regional Climate Change in Relation to Atmospheric Hydrologic Processes

    Science.gov (United States)

    Johnson, Donald R.

    2001-01-01

    This research was directed to the development and application of global isentropic modeling and analysis capabilities to describe hydrologic processes and energy exchange in the climate system, and discern regional climate change. An additional objective was to investigate the accuracy and theoretical limits of global climate predictability which are imposed by the inherent limitations of simulating trace constituent transport and the hydrologic processes of condensation, precipitation and cloud life cycles.

  17. Weak boson production from D0 and LHCb in the NNPDF global analysis

    CERN Document Server

    Rojo, Juan

    2016-01-01

    High-precision electroweak production measurements from the Tevatron and the LHC provide important constraints on the quark flavor separation in global PDF fits. In this contribution, we study the impact of the recent D0 W asymmetry measurements and of the LHCb W and Z Run I combination in the global NNPDF analysis. We find that these measurements can be described by NLO QCD theory and that they lead to a significant reduction of PDF uncertainties.

  18. Development of the Taiwanese Mandarin Main Concept Analysis (TM-MCA: Normative and Preliminary Aphasic Data

    Directory of Open Access Journals (Sweden)

    Anthony Pak Hin Kong

    2014-03-01

    Full Text Available Introduction Compared to the English literature, there is a great paucity of studies focusing on quantitative analysis of aphasic oral discourse in Chinese, especially for native speakers of Taiwanese-Mandarin residing in Taiwan. Several studies that investigated deficits of aphasic discourse have been conducted in Cantonese Chinese, including the Cantonese Linguistic Communication Measure (CLCM, Kong & Law, 2004, Main Concept Analysis (MCA; Kong, 2009, and Cantonese version of the Quantitative Production Analysis (Law, 2001; Yiu & Worrall, 1996. Clinical or research application of these systems to the Taiwanese population is limited by the differences of phonology, semantics, and grammar between Taiwanese Mandarin and Cantonese. The current study, therefore, aimed to develop a culturally appropriate Taiwan Mandarin Main Concept Analysis (TM-MCA, by translating and adapting the MCA in Cantonese (Kong, 2009, 2011, and then to validate the tool on the basis of normal speakers and people with aphasia in Taiwan. Method Picture stimuli and main concepts for the TM-MCA: Eight certified Taiwanese SLPs participated and listed all main concepts upon presentation of the sequential pictures in Kong (2009. A main concept referred to a statement consisting of only one main verb with two or more pieces of essential information accurately related to the pictures and informative about the content. All main concepts mentioned by six out of eight SLPs were included in a preliminary main concept list. Further validation of the list involved recruiting eight normal speakers to orally describe the same picture sets. Only those scored as Accurate and Complete (AC or Accurate but Incomplete (AI by at least five speakers were put in the final list. Normative and aphasic data collection and analysis: Thirty six native Taiwanese Mandarin speakers and ten individuals with aphasia orally perform the same picture description tasks. Six measures, including Number of Accurate

  19. Visualization and analysis of eddies in a global ocean simulation

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Sean J [Los Alamos National Laboratory; Hecht, Matthew W [Los Alamos National Laboratory; Petersen, Mark [Los Alamos National Laboratory; Strelitz, Richard [Los Alamos National Laboratory; Maltrud, Mathew E [Los Alamos National Laboratory; Ahrens, James P [Los Alamos National Laboratory; Hlawitschka, Mario [UC DAVIS; Hamann, Bernd [UC DAVIS

    2010-10-15

    Eddies at a scale of approximately one hundred kilometers have been shown to be surprisingly important to understanding large-scale transport of heat and nutrients in the ocean. Due to difficulties in observing the ocean directly, the behavior of eddies below the surface is not very well understood. To fill this gap, we employ a high-resolution simulation of the ocean developed at Los Alamos National Laboratory. Using large-scale parallel visualization and analysis tools, we produce three-dimensional images of ocean eddies, and also generate a census of eddy distribution and shape averaged over multiple simulation time steps, resulting in a world map of eddy characteristics. As expected from observational studies, our census reveals a higher concentration of eddies at the mid-latitudes than the equator. Our analysis further shows that mid-latitude eddies are thicker, within a range of 1000-2000m, while equatorial eddies are less than 100m thick.

  20. Global Carbon Fiber Composites Supply Chain Competitiveness Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Sujit Das, Josh Warren, Devin West, Susan M. Schexnayder

    2016-05-01

    This analysis identifies key opportunities in the carbon fiber supply chain where resources and investments can help advance the clean energy economy. The report focuses on four application areas — wind energy, aerospace, automotive, and pressure vessels — that top the list of industries using carbon fiber and carbon fiber reinforced polymers. For each of the four application areas, the report addresses the supply and demand trends within that sector, supply chain, and costs of carbon fiber and components.

  1. GC-MS analysis, preliminary phytochemical screening, physicochemical analysis and anti-diabetic activity of ethanol extract of Jasminum cuspidatum leaves

    Directory of Open Access Journals (Sweden)

    Singumsetty Vinay

    2014-12-01

    Full Text Available The purpose of the present study was investigating the GC-MS analysis, preliminary phytochemical screening, physicochemical analysis and anti-diabetic activity of ethanol extract of the leaves of Jasminum cuspidatum. The anti-diabetic activity was investigated in streptozotocin-induced diabetes rats with treatment of ethanol extract at the dose level of 200 and 400 mg/kg, which was compared with glibenclamide at a dose level of 4 mg/kg and the parameter measured being the blood glucose, total cholesterol, HDL, LDL, VLDL, triglycerides, and total protein. An oral glucose tolerance test (OGTT was also investigated in experimental rats. The GC-MS analysis revealed that the ethanol extract contained seven phytoconstituents. Preliminary phytochemical screening showed the presence of triterpenoids, flavonoids, glycosides and steroids. The result of in vivo anti-diabetic activity revealed that the ethanol extract of J. cuspidatum showed significant anti-diabetic activity.

  2. Gender inequality and HIV transmission: a global analysis

    Directory of Open Access Journals (Sweden)

    Eugene T Richardson

    2014-06-01

    Full Text Available Introduction: The HIV pandemic disproportionately impacts young women. Worldwide, young women aged 15–24 are infected with HIV at rates twice that of young men, and young women alone account for nearly a quarter of all new HIV infections. The incommensurate HIV incidence in young – often poor – women underscores how social and economic inequalities shape the HIV epidemic. Confluent social forces, including political and gender violence, poverty, racism, and sexism impede equal access to therapies and effective care, but most of all constrain the agency of women. Methods: HIV prevalence data was compiled from the 2010 UNAIDS Global Report. Gender inequality was assessed using the 2011 United Nations Human Development Report Gender Inequality Index (GII. Logistic regression models were created with predominant mode of transmission (heterosexual vs. MSM/IDU as the dependent variable and GII, Muslim vs. non-Muslim, Democracy Index, male circumcision rate, log gross national income (GNI per capita at purchasing power parity (PPP, and region as independent variables. Results and discussion: There is a significant correlation between having a predominantly heterosexual epidemic and high gender inequality across all models. There is not a significant association between whether a country is predominantly Muslim, has a high/low GNI at PPP, has a high/low circumcision rate, and its primary mode of transmission. In addition, there are only three countries that have had a generalized epidemic in the past but no longer have one: Cambodia, Honduras, and Eritrea. GII data are available only for Cambodia and Honduras, and these countries showed a 37 and 34% improvement, respectively, in their Gender Inequality Indices between 1995 and 2011. During the same period, both countries reduced their HIV prevalence below the 1% threshold of a generalized epidemic. This represents limited but compelling evidence that improvements in gender inequality can lead to

  3. A global analysis of human habitation on river deltas

    Science.gov (United States)

    Edmonds, Douglas; Caldwell, Rebecca; Baumgardner, Sarah; Paola, Chris; Roy, Samapriya; Nelson, Amelia; Nienhuis, Jaap

    2017-04-01

    km2 in 2020. Of the 300 million people currently living on deltas, roughly 69% live below 10 meters elevation in the so-called low elevation coastal zone that is particularly susceptible to coastal flooding. Interestingly, the population in the low elevation coastal zone is unevenly distributed. The largest number of people, approximately 24%, live between 4 and 6 m elevation. This elevation range is also more densely populated at 580 people per km2, which is nearly 12 times the global mean of 47 people per km2. We consider these estimates to be a minimum given that we define delta area from the geomorphic footprint.

  4. Effects of Social Psychological Phenomena on School Psychologists' Ethical Decision-Making: A Preliminary Empirical Analysis

    Science.gov (United States)

    Klose, Laurie McGarry; Lasser, Jon; Reardon, Robert F.

    2012-01-01

    This preliminary, exploratory study examines the impact of select social psychological phenomena on school-based ethical decision-making of school psychologists. Responses to vignettes and hypothetical statements reflecting several social psychological phenomena were collected from 106 practicing school psychologists. Participants were asked to…

  5. Preliminary analysis of species partitioning in the DWPF melter. Sludge batch 7A

    Energy Technology Data Exchange (ETDEWEB)

    Choi, A. S. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Smith III, F. G. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); McCabe, D. J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-01-01

    The work described in this report is preliminary in nature since its goal was to demonstrate the feasibility of estimating the off-gas carryover from the Defense Waste Processing Facility (DWPF) melter based on a simple mass balance using measured feed and glass pour stream (PS) compositions and time-averaged melter operating data over the duration of one canister-filling cycle.

  6. Preliminary bioelectrical impedance analysis (BIA) equation for body composition assessment in young females from Colombia

    Science.gov (United States)

    Caicedo-Eraso, J. C.; González-Correa, C. H.; González-Correa, C. A.

    2013-04-01

    A previous study showed that reported BIA equations for body composition are not suitable for Colombian population. The purpose of this study was to develop and validate a preliminary BIA equation for body composition assessment in young females from Colombia, using hydrodensitometry as reference method. A sample of 30 young females was evaluated. Inclusion and exclusion criteria were defined to minimize the variability of BIA. Height, weight, BIA, residual lung volume (RV) and underwater weight (UWW) were measured. A preliminary BIA equation was developed (r2 = 0.72, SEE = 2.48 kg) by stepwise multiple regression with fat-free mass (FFM) as dependent variable and weight, height and impedance measurements as independent variables. The quality of regression was evaluated and a cross-validation against 50% of sample confirmed that results obtained with the preliminary BIA equation is interchangeable with results obtained with hydrodensitometry (r2 = 0.84, SEE = 2.62 kg). The preliminary BIA equation can be used for body composition assessment in young females from Colombia until a definitive equation is developed. The next step will be increasing the sample, including a second reference method, as deuterium oxide dilution (D2O), and using multi-frequency BIA (MF-BIA). It would also be desirable to develop equations for males and other ethnic groups in Colombia.

  7. A preliminary study on electromyographic analysis of the paraspinal musculature in idiopathic scoliosis

    NARCIS (Netherlands)

    Cheung, J.; Halbertsma, J.P.; Veldhuizen, A.G.; Sluiter, W.J.; Maurits, N.M.; Cool, J.C.; van Horn, J.R.

    2005-01-01

    The paraspinal muscles have been implicated as a major causative factor in the progression of idiopathic scoliosis. Therefore, the objectives of this preliminary study were to measure the electromyographic activity (EMG) of the paraspinal muscles to determine its relationship to progression of the s

  8. Potential landslide activity affecting the archaeological site of Orongo (Easter Island-Chile): preliminary analysis

    Science.gov (United States)

    Margottini, C.; Delmonaco, G.; Spizzichino, D.; Pandolfi, O.; Crisostomo, R.; Nohe, S.

    2009-04-01

    landslide crowns are currently located in the same level some hundreds m at west, just below the plain where Orongo is founded, threatening the stability of the petroglyphs area. According to the above observations, although after preliminary superficial surveys, the potential landslide evolution of the area may be the following: i) slope toe affected by coastal erosion; ii) triggering of debris slide/fall in the middle-upper portion of the slope with failure depth of ca. 2.5-4m; iii) increasing of stress and retrogressive landslide activity (debris-slide) towards the crest zone. A possible development of the research will be based on implementation of a multi-temporal analysis of landslide activity through a 3D-GIS modeling coupled with a back analysis in order to define present slope stability conditions and possible evolution of the slope. This to provide useful tools for local authorities in implementing preventive landslide risk mitigation measures for the protection of the cultural heritage in Orongo.

  9. A literary analysis of global female identity, health, and equity.

    Science.gov (United States)

    Hagan, Teresa L; Cohen, Susan M

    2014-01-01

    Females' experiences of identity, health, and equity share similar features around the world. This literary analysis describes the narratives of 4 female protagonists from popular fiction novels to identify similarities between their personal and contextualized experiences. The impact these private realities and public structures have on female health will be used to demonstrate the universal ecological threats to women's health. In conclusion, we offer suggestions on how to incorporate the shared female movement from domination and separation toward liberation and connection into modern health care practices that emphasize shared decision making, open communication, and social activism.

  10. Global metabolite analysis of yeast: evaluation of sample preparation methods

    DEFF Research Database (Denmark)

    Villas-Bôas, Silas Granato; Højer-Pedersen, Jesper; Åkesson, Mats Fredrik;

    2005-01-01

    , which is the analysis of a large number of metabolites with very diverse chemical and physical properties. This work reports the leakage of intracellular metabolites observed during quenching yeast cells with cold methanol solution, the efficacy of six different methods for the extraction...... of intracellular metabolites, and the losses noticed during sample concentration by lyophilization and solvent evaporation. A more reliable procedure is suggested for quenching yeast cells with cold methanol solution, followed by extraction of intracellular metabolites by pure methanol. The method can be combined...

  11. A Sensitivity Study for an Evaluation of Input Parameters Effect on a Preliminary Probabilistic Tsunami Hazard Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Rhee, Hyun-Me; Kim, Min Kyu; Choi, In-Kil [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Sheen, Dong-Hoon [Chonnam National University, Gwangju (Korea, Republic of)

    2014-10-15

    The tsunami hazard analysis has been based on the seismic hazard analysis. The seismic hazard analysis has been performed by using the deterministic method and the probabilistic method. To consider the uncertainties in hazard analysis, the probabilistic method has been regarded as attractive approach. The various parameters and their weight are considered by using the logic tree approach in the probabilistic method. The uncertainties of parameters should be suggested by analyzing the sensitivity because the various parameters are used in the hazard analysis. To apply the probabilistic tsunami hazard analysis, the preliminary study for the Ulchin NPP site had been performed. The information on the fault sources which was published by the Atomic Energy Society of Japan (AESJ) had been used in the preliminary study. The tsunami propagation was simulated by using the TSUNAMI{sub 1}.0 which was developed by Japan Nuclear Energy Safety Organization (JNES). The wave parameters have been estimated from the result of tsunami simulation. In this study, the sensitivity analysis for the fault sources which were selected in the previous studies has been performed. To analyze the effect of the parameters, the sensitivity analysis for the E3 fault source which was published by AESJ was performed. The effect of the recurrence interval, the potential maximum magnitude, and the beta were suggested by the sensitivity analysis results. Level of annual exceedance probability has been affected by the recurrence interval.. Wave heights have been influenced by the potential maximum magnitude and the beta. In the future, the sensitivity analysis for the all fault sources in the western part of Japan which were published AESJ would be performed.

  12. A Workflow for Global Sensitivity Analysis of PBPK Models

    Directory of Open Access Journals (Sweden)

    Kevin eMcNally

    2011-06-01

    Full Text Available Physiologically based pharmacokinetic models have a potentially significant role in the development of a reliable predictive toxicity testing strategy. The structure of PBPK models are ideal frameworks into which disparate in vitro and in vivo data can be integrated and utilised to translate information generated, using alternative to animal measures of toxicity and human biological monitoring data, into plausible corresponding exposures. However, these models invariably include the description of well known non-linear biological processes such as, enzyme saturation and interactions between parameters such as, organ mass and body mass. Therefore, an appropriate sensitivity analysis technique is required which can quantify the influences associated with individual parameters, interactions between parameters and any non-linear processes. In this report we have defined a workflow for sensitivity analysis of PBPK models that is computationally feasible, accounts for interactions between parameters, and can be displayed in the form of a bar chart and cumulative sum line (Lowry plot, which we believe is intuitive and appropriate for toxicologists, risk assessors and regulators.

  13. Damage detection and quantification using mode curvature variation on framed structures: analysis of the preliminary results

    Science.gov (United States)

    Iacovino, Chiara; Ditommaso, Rocco; Auletta, Gianluca; Ponzo, Felice C.

    2017-04-01

    Continuous monitoring based on vibrational identification methods is increasingly employed for the evaluation of the state of health of existing buildings after strong motion earthquake. Different damage identification methods are based on the variations of damage indices defined in terms modal (eigenfrequencies, mode shapes, and modal damping) and/or non-modal parameters. Most of simplified methods for structural health monitoring and damage detection are based on the evaluation of the dynamic characteristics evolution associated to the fundamental mode of vibration of a monitored structure. Aim of this work is the upgrade of an existing method for damage localization on framed structures during a moderate/destructive earthquake. The existing version of the method is based on the comparison of the geometric characteristics (with particular reference to the mode curvature) exhibited by the structures, related to fundamental mode of vibration, before and during an earthquake. The approach is based on the use of a nonlinear filter, the band-variable filter, based on the Stockwell Transform able to extract the nonlinear response of each mode of vibration. The new version of the method provides the possibility to quantify a possible damage occurred on the monitored structure linking the mode curvature variation with the maximum inter-story drift. This paper shows the preliminary results obtained from several simulations on nonlinear numerical models of reinforced concrete framed structures, designed for only gravity loads, without and with the presence of infill panels. Furthermore, a correlation between maximum mode curvature difference and maximum inter-story drift has been defined for the different numerical models in order to quantify the structural damage. Acknowledgements This study was partially funded by the Italian Department of Civil Protection within the project DPC-RELUIS 2016 - RS4 ''Seismic observatory of structures and health monitoring'' and by the

  14. Synthesis, Spectral Analysis and Preliminary in Vitro Evaluation of Some Tetrapyrrolic Complexes with 3d Metal Ions

    Directory of Open Access Journals (Sweden)

    Radu Socoteanu

    2015-08-01

    Full Text Available In this paper, two tetrapyrrolic complexes, Zn(II-5-(3-hydroxyphenyl-10,15,20-tris-(4-acetoxy-3-methoxyphenylporphyrin and Cu(II-5-(3-hydroxyphenyl-10,15,20-tris-(4-acetoxy-3-methoxyphenylporphyrin were synthesized, and characterized from a spectral and biological point of view. The study provided data concerning the behavior of identical external substituents vs. two different core insertions. Some of the properties of the proposed tetrapyrrolic structures were highlighted, having photodynamic therapy of cancer as a targeted biomedical application. Elemental analysis, NMR, FTIR and UV-Vis data in various solvents were provided. A preliminary in vitro study on normal and cancer cultured cells was carried out for biocompatibility assessment in dark conditions. The preliminary in vitro study performed on human peripheral mononuclear cells exposed to tetrapyrrolic compounds (2 µM showed that the proposed compounds had a convenient cytotoxic profile on human normal peripheral blood mononuclear cells under dark conditions. Meanwhile, the investigated compounds reduced the number of metabolically active breast tumor MCF-7 cells, with the exception of Zn(II complex-containing a symmetrical ligand. Accordingly, preliminary in vitro data suggest that the proposed tetrapyrrolic compounds are good candidates for PDT, as they limit tumor expansion even under dark conditions, whilst sparing normal cells.

  15. How to assess the Efficiency and "Uncertainty" of Global Sensitivity Analysis?

    Science.gov (United States)

    Haghnegahdar, Amin; Razavi, Saman

    2016-04-01

    Sensitivity analysis (SA) is an important paradigm for understanding model behavior, characterizing uncertainty, improving model calibration, etc. Conventional "global" SA (GSA) approaches are rooted in different philosophies, resulting in different and sometime conflicting and/or counter-intuitive assessment of sensitivity. Moreover, most global sensitivity techniques are highly computationally demanding to be able to generate robust and stable sensitivity metrics over the entire model response surface. Accordingly, a novel sensitivity analysis method called Variogram Analysis of Response Surfaces (VARS) is introduced to overcome the aforementioned issues. VARS uses the Variogram concept to efficiently provide a comprehensive assessment of global sensitivity across a range of scales within the parameter space. Based on the VARS principles, in this study we present innovative ideas to assess (1) the efficiency of GSA algorithms and (2) the level of confidence we can assign to a sensitivity assessment. We use multiple hydrological models with different levels of complexity to explain the new ideas.

  16. Global Analysis of Palmitoylated Proteins in Toxoplasma gondii.

    Science.gov (United States)

    Foe, Ian T; Child, Matthew A; Majmudar, Jaimeen D; Krishnamurthy, Shruthi; van der Linden, Wouter A; Ward, Gary E; Martin, Brent R; Bogyo, Matthew

    2015-10-14

    Post-translational modifications (PTMs) such as palmitoylation are critical for the lytic cycle of the protozoan parasite Toxoplasma gondii. While palmitoylation is involved in invasion, motility, and cell morphology, the proteins that utilize this PTM remain largely unknown. Using a chemical proteomic approach, we report a comprehensive analysis of palmitoylated proteins in T. gondii, identifying a total of 282 proteins, including cytosolic, membrane-associated, and transmembrane proteins. From this large set of palmitoylated targets, we validate palmitoylation of proteins involved in motility (myosin light chain 1, myosin A), cell morphology (PhIL1), and host cell invasion (apical membrane antigen 1, AMA1). Further studies reveal that blocking AMA1 palmitoylation enhances the release of AMA1 and other invasion-related proteins from apical secretory organelles, suggesting a previously unrecognized role for AMA1. These findings suggest that palmitoylation is ubiquitous throughout the T. gondii proteome and reveal insights into the biology of this important human pathogen.

  17. Global Carbon Fiber Composites Supply Chain Competitiveness Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Das, Sujit [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Warren, Josh [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); West, Devin [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Schexnayder, Susan M. [Univ. of Tennessee, Knoxville, TN (United States)

    2016-05-01

    This study identifies key opportunities in the carbon fiber supply chain where the United States Department of Energy's Office of Energy Efficiency and Renewable Energy resources and investments can help the United States achieve or maintain a competitive advantage. The report focuses on four application areas--wind energy, aerospace, automotive, and pressure vessels--that top the list of industries using carbon fiber and carbon fiber reinforced polymers and are also particularly relevant to EERE's mission. For each of the four application areas, the report addresses the supply and demand trends within that sector, supply chain, and costs of carbon fiber and components, all contributing to a competitiveness assessment that addresses the United States' role in future industry growth. This report was prepared by researchers at Oak Ridge National Laboratory and the University of Tennessee for the Clean Energy Manufacturing Analysis Center.

  18. Global gene expression analysis for evaluation and design of biomaterials

    Directory of Open Access Journals (Sweden)

    Nobutaka Hanagata, Taro Takemura and Takashi Minowa

    2010-01-01

    Full Text Available Comprehensive gene expression analysis using DNA microarrays has become a widespread technique in molecular biological research. In the biomaterials field, it is used to evaluate the biocompatibility or cellular toxicity of metals, polymers and ceramics. Studies in this field have extracted differentially expressed genes in the context of differences in cellular responses among multiple materials. Based on these genes, the effects of materials on cells at the molecular level have been examined. Expression data ranging from several to tens of thousands of genes can be obtained from DNA microarrays. For this reason, several tens or hundreds of differentially expressed genes are often present in different materials. In this review, we outline the principles of DNA microarrays, and provide an introduction to methods of extracting information which is useful for evaluating and designing biomaterials from comprehensive gene expression data.

  19. Current Global Almond Trade and Its Consumption Patterns Analysis

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    This article aims to investigate the current situation of the international almond trade and its consumption patterns.Traditionally, almonds are characterized by their good taste and high quality and regarded as an ideal source of several natural health nutrients. At present, the United States is the leading almond producer and exporter in the world, accompanied by Germany, Spain and Japan, the biggest almond importing countries. In order to study almond consumption patterns, two indicators were used in our study, the Food Consumer Location Ratio (FCLR) and the Food Consumer Location Relative Ratio (FCLRR). Furthermore, to identify the almond consumption groups, we carried out two cluster analyses based on FCLR and FCLRR values. Finally, an analysis of the factors which have an impact on a country's almond consumption was conducted. It shows that income level, endowment of resources and tradition as well as dietary habits are key factors that help to shape a country's almond consumption pattern.

  20. Global analysis of the sporulation pathway of Clostridium difficile.

    Directory of Open Access Journals (Sweden)

    Kelly A Fimlaid

    Full Text Available The Gram-positive, spore-forming pathogen Clostridium difficile is the leading definable cause of healthcare-associated diarrhea worldwide. C. difficile infections are difficult to treat because of their frequent recurrence, which can cause life-threatening complications such as pseudomembranous colitis. The spores of C. difficile are responsible for these high rates of recurrence, since they are the major transmissive form of the organism and resistant to antibiotics and many disinfectants. Despite the importance of spores to the pathogenesis of C. difficile, little is known about their composition or formation. Based on studies in Bacillus subtilis and other Clostridium spp., the sigma factors σ(F, σ(E, σ(G, and σ(K are predicted to control the transcription of genes required for sporulation, although their specific functions vary depending on the organism. In order to determine the roles of σ(F, σ(E, σ(G, and σ(K in regulating C. difficile sporulation, we generated loss-of-function mutations in genes encoding these sporulation sigma factors and performed RNA-Sequencing to identify specific sigma factor-dependent genes. This analysis identified 224 genes whose expression was collectively activated by sporulation sigma factors: 183 were σ(F-dependent, 169 were σ(E-dependent, 34 were σ(G-dependent, and 31 were σ(K-dependent. In contrast with B. subtilis, C. difficile σ(E was dispensable for σ(G activation, σ(G was dispensable for σ(K activation, and σ(F was required for post-translationally activating σ(G. Collectively, these results provide the first genome-wide transcriptional analysis of genes induced by specific sporulation sigma factors in the Clostridia and highlight that diverse mechanisms regulate sporulation sigma factor activity in the Firmicutes.

  1. Hayabusa Recovery, Curation and Preliminary Sample Analysis: Lessons Learned from Recent Sample Return Mission

    Science.gov (United States)

    Zolensky, Michael E.

    2011-01-01

    analytical activities before settling on a database design - Hayabusa has done a better job of this. Also, analysis teams must not be permitted to devise their own sample naming schemes. The sample handling and storage facilities for Hayabusa are the finest that exist, and we are now modifying Stardust curation to take advantage of the Hayabusa facilities. Remote storage of a sample subset is desirable. Preliminary Examination (PE) of Samples: There must be some determination of the state and quantity of the returned samples, to provide a necessary guide to persons requesting samples and oversight committees tasked with sample curation oversight. Hayabusa s sample PE, which is called HASPET, was designed so that late additions to the analysis protocols were possible, as new analytical techniques became available. A small but representative number of recovered grains are being subjected to in-depth characterization. The bulk of the recovered samples are being left untouched, to limit contamination. The HASPET plan takes maximum advantage of the unique strengths of sample return missions

  2. An Analysis of the Vulnerability of Global Drinking Water Access to Climate-related Hazards

    Science.gov (United States)

    Elliott, M.; Banerjee, O.; Christenson, E.; Holcomb, D.; Hamrick, L.; Bartram, J.

    2014-12-01

    Global drinking water access targets are formulated around "sustainable access." Global climate change (GCC) and associated hazards threaten the sustainability of drinking water supply. Extensive literature exists on the impacts of GCC on precipitation and water resources. However, the literature lacks a credible analysis of the vulnerability of global drinking water access. This research reports on an analysis of the current vulnerability of drinking water access due to three climate-related hazardous events: cyclone, drought and flood. An ArcGIS database was built incorporating the following: population density, hazardous event frequency, drinking water technologies in use and adaptive capacity. Two global grids were incorporated first: (1) LandScanTM global population distribution; and (2) frequency of cyclone, drought and flood from ~1980-2000 from Columbia University Center for Hazards Risk Research (CHRR). Population density was used to characterize cells as urban or rural and country-level urban/rural drinking water technologies in use were added based on the WHO/UNICEF Joint Monitoring Programme data. Expert assessment of the resilience of each technology to each hazardous event based on WHO/DFID Vision 2030 were quantified and added to the database. Finally, country-level adaptive capacity was drawn from the "readiness" parameter of the Global Adaptation Index (GaIn). ArcGIS Model Builder and Python were used to automate the addition of datasets. This presentation will report on the results of this analysis, the first credible attempt to assess the vulnerability of global drinking water access to climate-related hazardous events. This analysis has yielded country-level scores and maps displaying the ranking of exposure score (for flood, drought, cyclone, and all three in aggregate) and the corresponding country-level vulnerability scores and rankings incorporating the impact of drinking water technologies and adaptive capacity (Figure 1).

  3. A global seasonal surface ocean climatology of phytoplankton types based on CHEMTAX analysis of HPLC pigments

    Science.gov (United States)

    Swan, Chantal M.; Vogt, Meike; Gruber, Nicolas; Laufkoetter, Charlotte

    2016-03-01

    Much advancement has been made in recent years in field data assimilation, remote sensing and ecosystem modeling, yet our global view of phytoplankton biogeography beyond chlorophyll biomass is still a cursory taxonomic picture with vast areas of the open ocean requiring field validations. High performance liquid chromatography (HPLC) pigment data combined with inverse methods offer an advantage over many other phytoplankton quantification measures by way of providing an immediate perspective of the whole phytoplankton community in a sample as a function of chlorophyll biomass. Historically, such chemotaxonomic analysis has been conducted mainly at local spatial and temporal scales in the ocean. Here, we apply a widely tested inverse approach, CHEMTAX, to a global climatology of pigment observations from HPLC. This study marks the first systematic and objective global application of CHEMTAX, yielding a seasonal climatology comprised of ~1500 1°×1° global grid points of the major phytoplankton pigment types in the ocean characterizing cyanobacteria, haptophytes, chlorophytes, cryptophytes, dinoflagellates, and diatoms, with results validated against prior regional studies where possible. Key findings from this new global view of specific phytoplankton abundances from pigments are a) the large global proportion of marine haptophytes (comprising 32±5% of total chlorophyll), whose biogeochemical functional roles are relatively unknown, and b) the contrasting spatial scales of complexity in global community structure that can be explained in part by regional oceanographic conditions. The results are publically accessible via

  4. Preliminary Axial Flow Turbine Design and Off-Design Performance Analysis Methods for Rotary Wing Aircraft Engines. Part 1; Validation

    Science.gov (United States)

    Chen, Shu-cheng, S.

    2009-01-01

    For the preliminary design and the off-design performance analysis of axial flow turbines, a pair of intermediate level-of-fidelity computer codes, TD2-2 (design; reference 1) and AXOD (off-design; reference 2), are being evaluated for use in turbine design and performance prediction of the modern high performance aircraft engines. TD2-2 employs a streamline curvature method for design, while AXOD approaches the flow analysis with an equal radius-height domain decomposition strategy. Both methods resolve only the flows in the annulus region while modeling the impact introduced by the blade rows. The mathematical formulations and derivations involved in both methods are documented in references 3, 4 for TD2-2) and in reference 5 (for AXOD). The focus of this paper is to discuss the fundamental issues of applicability and compatibility of the two codes as a pair of companion pieces, to perform preliminary design and off-design analysis for modern aircraft engine turbines. Two validation cases for the design and the off-design prediction using TD2-2 and AXOD conducted on two existing high efficiency turbines, developed and tested in the NASA/GE Energy Efficient Engine (GE-E3) Program, the High Pressure Turbine (HPT; two stages, air cooled) and the Low Pressure Turbine (LPT; five stages, un-cooled), are provided in support of the analysis and discussion presented in this paper.

  5. Analysis of Sea Ice Cover Sensitivity in Global Climate Model

    Directory of Open Access Journals (Sweden)

    V. P. Parhomenko

    2014-01-01

    Full Text Available The paper presents joint calculations using a 3D atmospheric general circulation model, an ocean model, and a sea ice evolution model. The purpose of the work is to analyze a seasonal and annual evolution of sea ice, long-term variability of a model ice cover, and its sensitivity to some parameters of model as well to define atmosphere-ice-ocean interaction.Results of 100 years simulations of Arctic basin sea ice evolution are analyzed. There are significant (about 0.5 m inter-annual fluctuations of an ice cover.The ice - atmosphere sensible heat flux reduced by 10% leads to the growth of average sea ice thickness within the limits of 0.05 m – 0.1 m. However in separate spatial points the thickness decreases up to 0.5 m. An analysis of the seasonably changing average ice thickness with decreasing, as compared to the basic variant by 0.05 of clear sea ice albedo and that of snow shows the ice thickness reduction in a range from 0.2 m up to 0.6 m, and the change maximum falls for the summer season of intensive melting. The spatial distribution of ice thickness changes shows, that on the large part of the Arctic Ocean there was a reduction of ice thickness down to 1 m. However, there is also an area of some increase of the ice layer basically in a range up to 0.2 m (Beaufort Sea. The 0.05 decrease of sea ice snow albedo leads to reduction of average ice thickness approximately by 0.2 m, and this value slightly depends on a season. In the following experiment the ocean – ice thermal interaction influence on the ice cover is estimated. It is carried out by increase of a heat flux from ocean to the bottom surface of sea ice by 2 W/sq. m in comparison with base variant. The analysis demonstrates, that the average ice thickness reduces in a range from 0.2 m to 0.35 m. There are small seasonal changes of this value.The numerical experiments results have shown, that an ice cover and its seasonal evolution rather strongly depend on varied parameters

  6. The ZH ratio Analysis of Global Seismic Data

    Science.gov (United States)

    Yano, T.; Shikato, S.; Rivera, L.; Tanimoto, T.

    2007-12-01

    The ZH ratio, the ratio of vertical to horizontal component of the fundamental Rayleigh wave as a function of frequency, is an alternative approach to phase/group velocity analysis for constructing the S-wave velocity structure. In this study, teleseismic Rayleigh wave data for the frequency range between 0.004Hz to 0.04Hz is used to investigate the interior structure. We have analyzed most of the GEOSCOPE network data and some IRIS GSN stations using a technique developed by Tanimoto and Rivera (2007). Stable estimates of the ZH ratios were obtained for the frequency range for most stations. We have performed the inversion of the measured ZH ratios for the structure in the crust and mantle by using nonlinear iterative scheme. The depth sensitivity kernels for inversion are numerically calculated. Depth sensitivity of the lowest frequency extends to depths beyond 500 km but the sensitivity of the overall data for the frequency band extends down to about 300km. We found that an appropriate selection of an initial model, particularly the depth of Mohorovicic discontinuity, is important for this inversion. The inversion result depends on the initial model and turned out to be non-unique. We have constructed the initial model from the CRUST 2.0. Inversion with equal weighting to each data point tends to reduce variance of certain frequency range only. Therefore, we have developed a scheme to increase weighting to data points that do not fit well after the fifth iteration. This occurs more often for low frequency range, 0.004-0.007Hz. After fitting the lower frequency region, the low velocity zone around a depth of 100km is observed under some stations such as KIP (Kipapa, Hawaii) and ATD (Arta Cave, Djibouti). We have also carried out an analysis on the resolving power of data by examining the eigenvalues-eigenvectors of the least-squares problem. Unfortunately, the normal matrix usually has 1-2 very large eigenvalues, followed by much smaller eigenvalues. The third

  7. New limits on intrinsic charm in the nucleon from global analysis of parton distributions

    CERN Document Server

    Jimenez-Delgado, P; Londergan, J T; Melnitchouk, W

    2014-01-01

    We present a new global QCD analysis of parton distribution functions, allowing for possible nonperturbative or intrinsic charm (IC) contributions in the nucleon inspired by light-front models. The analysis makes use of the full range of available high energy scattering data for Q^2 > 1 GeV^2 and W^2 > 3.5 GeV^2, including SLAC proton and deuteron deep-inelastic scattering cross sections that were excluded in previously global analyses. The SLAC data in particular place more stringent constraints on the momentum carried by IC, with _IC _IC = 0.13 +- 0.04%, but have a very large chi^2 value.

  8. Central receiver solar thermal power system. Phase 1. CDRL item 2; Pilot Plant preliminary design report. Volume II. System decription and system analysis

    Energy Technology Data Exchange (ETDEWEB)

    Hallet, Jr., R. W.; Gervais, R. L.

    1977-10-01

    An active system analysis and integration effort has been maintained. These activities have included the transformation of initial program requirements into a preliminary system design, the evolution of subsystem requirements which lay the foundation for subsystem design and test activity, and the overseeing of the final preliminary design effort to ensure that the subsystems are operationally compatible and capable of producing electricity at the lowest possible cost per unit of energy. Volume II of the Preliminary Design Report presents the results of the overall system effort that went on during this contract. The effort is assumed to include not only the total system definition and design but also all subsystem interactions.

  9. Global dynamics of triaxial galactic models through frequency map analysis

    Science.gov (United States)

    Papaphilippou, Y.; Laskar, J.

    1998-01-01

    In a previous article (Papaphilippou & Laskar 1996), we used the frequency map analysis for studying the dynamics of the axisymmetric softened version of the logarithmic potential. The method is now applied to its 3-dimensional generalisation in order to deepen our knowledge regarding the dynamics of triaxial power-law galactic models. The principal dynamical features of the system are reviewed within the appropriate Hamiltonian frame of reference. The quasi-periodic approximations furnished by the method permit to clarify the dynamics of the principal types of orbits and their connection with perturbations of integrable cases of the general Hamiltonian. All the fine details of the dynamics associated with the addition of the third degree of freedom are displayed in the complete frequency map, a direct representation of the system's Arnol'd web. The influence of resonant lines and the extent of the chaotic zones are directly visualized in the physical space of the system. This approach reveals many unknown dynamical features of triaxial galactic potentials and gives strong indications that chaos should be an innate characteristic of triaxial configurations. The impact of these results in the construction of self-consistent galactic models are finally discussed.

  10. Global analysis of lysine acetylation in strawberry leaves

    Directory of Open Access Journals (Sweden)

    Xianping eFang

    2015-09-01

    Full Text Available Protein lysine acetylation is a reversible and dynamic post-translational modification. It plays an important role in regulating diverse cellular processes including chromatin dynamic, metabolic pathways and transcription in both prokaryotes and eukaryotes. Although studies of lysine acetylome in plants have been reported, the throughput was not high enough, hindering the deep understanding of lysine acetylation in plant physiology and pathology. In this study, taking advantages of anti-acetyllysine-based enrichment and high-sensitive-mass spectrometer, we applied an integrated proteomic approach to comprehensively investigate lysine acetylome in strawberry. In total, we identified 1392 acetylation sites in 684 proteins, representing the largest dataset of acetylome in plants to date. To reveal the functional impacts of lysine acetylation in strawberry, intensive bioinformatic analysis was performed. The results significantly expanded our current understanding of plant acetylome and demonstrated that lysine acetylation is involved in multiple cellular metabolism and cellular processes. More interestingly, nearly 50% of all acetylated proteins identified in this work were localized in chloroplast and the vital role of lysine acetylation in photosynthesis was also revealed. Taken together, this study not only established the most extensive lysine acetylome in plants to date, but also systematically suggests the significant and unique roles of lysine acetylation in plants.

  11. Modelling the Milky Way galaxy: global mode analysis

    CERN Document Server

    Polyachenko, Evgeny; Just, Andreas

    2016-01-01

    A stellar dynamical model of the Milky Way Galaxy composed of an exponential disc, a cuspy bulge, and a NFW halo is studied. The model is subject to instability that form a bar with a pattern speed of 56 km/s/kpc and an exponential growth timescale of 250 Myr. The bar slows down after formation with a variable rate, which is largest just after formation, then decrease to 7 km/s/kpc per Gyr. If the live halo of particles is substituted by a fixed external potential (rigid halo), the exponential growth timescale increases to 500 Myr, which would increase bar formation time from 3 to 6 Gyr in a disc represented by $10^{11}$ stars. Spectral analysis combined with time Fourier transformation shows the presence of bisymmetric `quasi-modes' with pattern speeds smaller than that of the bar. These modes disappear when the bar is strong enough, meanwhile a new nonlinear mode coupled to the bar appears with a pattern speed about 70 ... 75 % of the bar. This mode has a form of a trailing spiral extending to its corotatio...

  12. Analysis of experimental studies on gully erosion: a global review

    Science.gov (United States)

    Castillo, Carlos; Gómez, Jose A.

    2015-04-01

    Research on gully erosion has increased significantly in the last decades. Despite the growing interest on the topic, relevant knowledge gaps still remain a challenge for gully erosion researchers (Poesen, 2011). Moreover, many of these studies are mainly descriptive, with little quantitative data allowing a comparison of the severity of the processes among different environments and conditions. The aim of this communication is to analyse the available experimental data in gully erosion literature involving quantitative information from the Web of Science datasets. Our objective is to investigate relevant trends of this type of erosion on the world scale. We have evaluated the role of gully erosion in the overall soil losses as well as the magnitude of the morphological variables. Also, we analysed the characteristics of image-based and field surveys regarding the technique employed, duration and data collection frequency. In this communication, we intend to provide insights on the evolution of gully erosion research up to the present moment in order to gain perspectives on the design of future efforts in the topic. References Poesen, J. 2011. Challenges in gully erosion research. Landform Analysis, Vol. 17: 5-9.

  13. A global analysis of adaptive evolution of operons in cyanobacteria.

    Science.gov (United States)

    Memon, Danish; Singh, Abhay K; Pakrasi, Himadri B; Wangikar, Pramod P

    2013-02-01

    Operons are an important feature of prokaryotic genomes. Evolution of operons is hypothesized to be adaptive and has contributed significantly towards coordinated optimization of functions. Two conflicting theories, based on (i) in situ formation to achieve co-regulation and (ii) horizontal gene transfer of functionally linked gene clusters, are generally considered to explain why and how operons have evolved. Furthermore, effects of operon evolution on genomic traits such as intergenic spacing, operon size and co-regulation are relatively less explored. Based on the conservation level in a set of diverse prokaryotes, we categorize the operonic gene pair associations and in turn the operons as ancient and recently formed. This allowed us to perform a detailed analysis of operonic structure in cyanobacteria, a morphologically and physiologically diverse group of photoautotrophs. Clustering based on operon conservation showed significant similarity with the 16S rRNA-based phylogeny, which groups the cyanobacterial strains into three clades. Clade C, dominated by strains that are believed to have undergone genome reduction, shows a larger fraction of operonic genes that are tightly packed in larger sized operons. Ancient operons are in general larger, more tightly packed, better optimized for co-regulation and part of key cellular processes. A sub-clade within Clade B, which includes Synechocystis sp. PCC 6803, shows a reverse trend in intergenic spacing. Our results suggest that while in situ formation and vertical descent may be a dominant mechanism of operon evolution in cyanobacteria, optimization of intergenic spacing and co-regulation are part of an ongoing process in the life-cycle of operons.

  14. Global transcriptome analysis of the heat shock response ofshewanella oneidensis

    Energy Technology Data Exchange (ETDEWEB)

    Gao, Haichun; Wang, Sarah; Liu, Xueduan; Yan, Tinfeng; Wu, Liyou; Alm, Eric; Arkin, Adam P.; Thompson, Dorothea K.; Zhou, Jizhong

    2004-04-30

    Shewanella oneidensis is an important model organism for bioremediation studies because of its diverse respiratory capabilities. However, the genetic basis and regulatory mechanisms underlying the ability of S. oneidensis to survive and adapt to various environmentally relevant stresses is poorly understood. To define this organism's molecular response to elevated growth temperatures, temporal gene expression profiles were examined in cells subjected to heat stress using whole-genome DNA microarrays for S. oneidensis MR-1. Approximately 15 percent (711) of the predicted S. oneidensis genes represented on the microarray were significantly up- or down-regulated (P < 0.05) over a 25-min period following shift to the heat shock temperature (42 C). As expected, the majority of S. oneidensis genes exhibiting homology to known chaperones and heat shock proteins (Hsps) were highly and transiently induced. In addition, a number of predicted genes encoding enzymes in glycolys is and the pentose cycle, [NiFe] dehydrogenase, serine proteases, transcriptional regulators (MerR, LysR, and TetR families), histidine kinases, and hypothetical proteins were induced in response to heat stress. Genes encoding membrane proteins were differentially expressed, suggesting that cells possibly alter their membrane composition or structure in response to variations in growth temperature. A substantial number of the genes encoding ribosomal proteins displayed down-regulated co-expression patterns in response to heat stress, as did genes encoding prophage and flagellar proteins. Finally, based on computational comparative analysis of the upstream promoter regions of S.oneidensis heat-inducible genes, a putative regulatory motif, showing high conservation to the Escherichia coli sigma 32-binding consensus sequence, was identified.

  15. Political priority of global oral health: an analysis of reasons for international neglect.

    Science.gov (United States)

    Benzian, Habib; Hobdell, Martin; Holmgren, Christopher; Yee, Robert; Monse, Bella; Barnard, Johannes T; van Palenstein Helderman, Wim

    2011-06-01

    Global Oral Health suffers from a lack of political attention, particularly in low- and middle-income countries. This paper analyses the reasons for this political neglect through the lens of four areas of political power: the power of the ideas, the power of the issue, the power of the actors, and the power of the political context (using a modified Political Power Framework by Shiffman and Smith. Lancet370 [2007] 1370). The analysis reveals that political priority for global oral health is low, resulting from a set of complex issues deeply rooted in the current global oral health sector, its stakeholders and their remit, the lack of coherence and coalescence; as well as the lack of agreement on the problem, its portrayal and possible solutions. The shortcomings and weaknesses demonstrated in the analysis range from rather basic matters, such as defining the issue in an agreed way, to complex and multi-levelled issues concerning appropriate data collection and agreement on adequate solutions. The political priority of Global Oral Health can only be improved by addressing the underlying reasons that resulted in the wide disconnection between the international health discourse and the small sector of Global Oral Health. We hope that this analysis may serve as a starting point for a long overdue, broad and candid international analysis of political, social, cultural, communication, financial and other factors related to better prioritisation of oral health. Without such an analysis and the resulting concerted action the inequities in Global Oral Health will grow and increasingly impact on health systems, development and, most importantly, human lives.

  16. Preliminary environmental analysis of a geopressured-geothermal test well in Brazoria County, Texas

    Energy Technology Data Exchange (ETDEWEB)

    White, W.A.; McGraw, M.; Gustavson, T.C.; Meriwether, J.

    1977-11-16

    Preliminary environmental data, including current land use, substrate lithology, soils, natural hazards, water resources, biological assemblages, meteorological data, and regulatory considerations have been collected and analyzed for approximately 150 km/sup 2/ of land near Chocolate Bayou, Brazoria County, Texas, in which a geopressured-geothermal test well is to be drilled in the fall of 1977. The study was designed to establish an environmental data base and to determine, within spatial constraints set by subsurface reservoir conditions, environmentally suitable sites for the proposed well. Preliminary analyses of data revealed the eed for focusing on the following areas: potential for subsidence and fault activation, susceptibility of test well and support facilities to fresh- and salt-water flooding, possible effects of produced saline waters on biological assemblages and groundwaer resources, distribution of expansive soils, and effect of drilling and associated support activities on known archeological-cultural resources.

  17. Preliminary Regional Analysis of the Kaguya Lunar Radar Sounder (LRS) Data through Eastern Mare Imbrium

    Science.gov (United States)

    Cooper, B.L.; Antonenko, I.; Yamaguchi, Y.; Osinski, G.; Ono, T.; Ku-mamoto, A.

    2009-01-01

    The Lunar Radar Sounder (LRS) experiment on board the Kaguya spacecraft is observing the subsurface structure of the Moon, using ground-penetrating radar operating in the frequency range of 5 MHz [1]. Because LRS data provides in-formation about lunar features below the surface, it allows us to improve our understanding of the processes that formed the Moon, and the post-formation changes that have occurred (such as basin formation and volcanism). We look at a swath of preliminary LRS data, that spans from 7 to 72 N, and from 2 to 10 W, passing through the eastern portion of Mare Imbrium (Figure 1). Using software, designed for the mineral exploration industry, we produce a preliminary, coarse 3D model, showing the regional structure beneath the study area. Future research will involve smaller subsets of the data in regions of interest, where finer structures, such as those identified in [2], can be studied.

  18. Preliminary results from fault-slip analysis of the Pärvie postglacial fault zone

    Science.gov (United States)

    Baeckstroem, A.; Rantakokko, N.; Jonsson, E.; Ask, M. V.

    2012-12-01

    We aim at constraining the paleostress field of a special type of intraplate faulting, triggered by the retreat of continental glaciers along the longest known post-glacial fault (PGF), the Pärvie PGF. It is 155 km long and consists of a series of 3-10 m high fault scarps; most of them west-facing and north-northeast trending. The fault displaces postglacial sediments (Lagerbäck 1979). The displacement is interpreted to have been caused by a great earthquake (M≤8.2; Arvidson 1996) at the end or just after the last glaciation (~10 ky B.P.). The fault zone is still active on the microseismic scale; however, the regional stress field is yet relatively poorly constrained (Lindblom 2011). The PGFs in North Fennoscandia may have formed in the Precambrian (e.g. Olesen et al. 1992). Nevertheless, the stress history of the Pärvie PGF before the last glaciation is poorly known. To reconstruct its stress history, we have performed fault-slip analysis of fault slip data that reactivated the fault. We have collected fault slip data from a profile of outcrops across the Pärvie PGF in the valley wall in the Corruvagge valley in northern Sweden. Cross-cutting relationships, fracture mineralization and brittle behavior of the rock have been used to unravel the brittle history of the fault. At least three paleostress regimes have been identified. Preliminary results indicate that early formed brittle structures where the fracture filling minerals are dominated by amphibole and plagioclase were subjected to a strike-slip stress regime with a small component of extension. The two relatively younger stages of the brittle development of this structure can be related to a compressive respectively an extensional stress-field. The mineral assemblage in the two later brittle deformations is dominated by epidote. Several fractures from the younger stages are cross-cutting and displacing the older events. The mineral assemblages related to the younger stages show several fault

  19. Crystallization and preliminary X-ray diffraction analysis of HML, a lectin from the red marine alga Hypnea musciformis

    Energy Technology Data Exchange (ETDEWEB)

    Nagano, Celso S.; Gallego del Sol, Francisca [Instituto de Biomedicina de Valencia, CSIC, Valencia (Spain); Cavada, Benildo S.; Nascimento, Kyria Santiago Do [Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Fortaleza, CE 60451-970 (Brazil); Nunes, Eudismar Vale; Sampaio, Alexandre H. [Laboratorio de Bioquímica Marinha, Departamento de Engenharia de Pesca, Universidade Federal do Ceará, Fortaleza, CE 60451-970 (Brazil); Calvete, Juan J., E-mail: jcalvete@ibv.csic.es [Instituto de Biomedicina de Valencia, CSIC, Valencia (Spain)

    2005-11-01

    The crystallization and preliminary X-ray diffraction analysis of a red marine alga lectin isolated from H. musciformis is reported. HML, a lectin from the red marine alga Hypnea musciformis, defines a novel lectin family. Orthorhombic crystals of HML belonging to space group P2{sub 1}2{sub 1}2{sub 1} grew within three weeks at 293 K using the hanging-drop vapour-diffusion method. A complete data set was collected at 2.4 Å resolution. HML is the first marine alga lectin to be crystallized.

  20. Test for Nonlinear Input Output Relations in SISO Systems by Preliminary Data Analysis

    DEFF Research Database (Denmark)

    Knudsen, Torben

    2000-01-01

    This paper discusses and develops preliminary statistical tests for detecting nonlinearities in the deterministic part of SISO systems with noise. The most referenced method is unreliable for common noise processes as e.g.\\ colored. Therefore two new methods based on superposition and sinus input...... are developed. They are much more robust, especially the sinus method which is reliable also for colored, heavy tailed or skew distributed noise....