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Sample records for preliminary experiments established

  1. PRELIMINARY ACCOUNTING WORKS FOR THE ESTABLISHMENT OF FINANCIAL STATEMENTS

    OpenAIRE

    HOLT GHEORGHE

    2017-01-01

    The preparation of financial statements is a complex process of aggregation of data and accounting information in the perspective of establishing economic and financial indicators. The adoption of a uniform set of preliminary accounting work for the closure of the current financial exercises is the only way for romanian companies to ensure that their financial situations are reliable, and on this basis, the users can make the best decisions. According to IASB Framework, the objective...

  2. PRELIMINARY ACCOUNTING WORKS FOR THE ESTABLISHMENT OF FINANCIAL STATEMENTS

    Directory of Open Access Journals (Sweden)

    HOLT GHEORGHE

    2017-02-01

    Full Text Available The preparation of financial statements is a complex process of aggregation of data and accounting information in the perspective of establishing economic and financial indicators. The adoption of a uniform set of preliminary accounting work for the closure of the current financial exercises is the only way for romanian companies to ensure that their financial situations are reliable, and on this basis, the users can make the best decisions. According to IASB Framework, the objective of financial statements is to provide information about the financial position, performance and changes in financial position of an enterprise that is useful to a wide range of users in making economic decisions: managers, shareholders, prospective investors, financial institutions, suppliers, customers, employees, competitors, general public, governments. The complexity of the accounting works preceding the financial statement preparation is determined by the large volume of theoretical and practical knowledge that can be influenced by the following factors: different accounting policies, accounting estimates, professional judgment, verifiability, measurability, fraud and error. The main objective of this scientific paper is to highlight the importance of preliminary accounting works for the annual financial statements establisment, focusing on the presentation of their chronological evidence.

  3. Spreading the Experience of Preschool Educational Establishments

    Directory of Open Access Journals (Sweden)

    V. M. Dyukov

    2012-01-01

    Full Text Available The paper observes the issue of spreading the innovative experience of municipal preschool educational establishments (MPEE. The author outlines the ways of spreading the ideas of «Development Program of MPEE» and « Educational Program of MPEE» worked out according to the federal state requirements. Theoretical methodological basis of the research combines the fundamental studies of the last century’s Russian teachers and psychologists: L. S. Vygodsky, A. N. Leontyev, L. I. Bozhovitch, A. V. Zaporozhets, V. V. Davydov, etc. Based on their studies, a series of teaching methodical manuals was developed in the Institute of Reflexive Psychology of Creativity and Humanizing the Education at the International Academy of Humanizing the Education, Sotchi–Magdeburg: «Russian Education 2020 – the Model of Preschool Education» and «Pedagogic Innovations in MPEE of Innovative Type».In author’s opinion, the outcome of the research can promote the modernization efficiency in preschool education.

  4. Spreading the Experience of Preschool Educational Establishments

    Directory of Open Access Journals (Sweden)

    V. M. Dyukov

    2015-02-01

    Full Text Available The paper observes the issue of spreading the innovative experience of municipal preschool educational establishments (MPEE. The author outlines the ways of spreading the ideas of «Development Program of MPEE» and « Educational Program of MPEE» worked out according to the federal state requirements. Theoretical methodological basis of the research combines the fundamental studies of the last century’s Russian teachers and psychologists: L. S. Vygodsky, A. N. Leontyev, L. I. Bozhovitch, A. V. Zaporozhets, V. V. Davydov, etc. Based on their studies, a series of teaching methodical manuals was developed in the Institute of Reflexive Psychology of Creativity and Humanizing the Education at the International Academy of Humanizing the Education, Sotchi–Magdeburg: «Russian Education 2020 – the Model of Preschool Education» and «Pedagogic Innovations in MPEE of Innovative Type».In author’s opinion, the outcome of the research can promote the modernization efficiency in preschool education.

  5. Establishing laboratory standards for biological flight experiments

    Science.gov (United States)

    Young, Ronald B.; Moriarity, Debra M.

    1989-01-01

    The general objective of this research was to assess the effects of exposure to simulated microgravity on ultrastructural aspects of the contractile system in chicken skeletal muscle cells. This general objective had two specific experimental components: (1) the progression of changes in cell morphology, fusion, and patterns of contractile filament organization in muscle cell cultures grown in hollow fibers in the Clinostat were evaluated, with appropriate controls; (2) to initiate experiments in which muscle cells were grown on the surface of microcarrier beads. The ultimate objective of this second portion of the work is to determine if these beads can be rotated in a bioreactor and thereby obtain a more accurate approximation of the effects of simulated microgravity on differentiated muscle cells.

  6. Establishment and initial experiences from the Danish Ventral Hernia Database

    DEFF Research Database (Denmark)

    Helgstrand, F; Rosenberg, J; Bay-Nielsen, M

    2010-01-01

    PURPOSE: Outcome after ventral hernia repair is not optimal. The surgical technique relies on personal preferences or evidence from small-scale studies, rather than large-scale prospective data with high external validity. The purpose of this paper was to describe the establishment and potential...... of the Danish Ventral Hernia Database (DVHD). Furthermore, the first 2-year data from 2007 to 2008 are presented. METHODS: Registrations were based on surgeons' web registrations and validated by cross checking with data from the Danish National Patient Register. RESULTS: The DVHD was established in June 2006......, use of mesh or no mesh, type of suture material, and placement of the mesh. A total of 5,629 elective and 661 acute ventral hernia repairs were registered. After the first 2 years the registration rate was 70%. CONCLUSION: The first national ventral hernia database has been established. Preliminary...

  7. Preliminary experiments on quantification of skin condition

    Science.gov (United States)

    Kitajima, Kenzo; Iyatomi, Hitoshi

    2014-03-01

    In this study, we investigated a preliminary assessment method for skin conditions such as a moisturizing property and its fineness of the skin with an image analysis only. We captured a facial images from volunteer subjects aged between 30s and 60s by Pocket Micro (R) device (Scalar Co., Japan). This device has two image capturing modes; the normal mode and the non-reflection mode with the aid of the equipped polarization filter. We captured skin images from a total of 68 spots from subjects' face using both modes (i.e. total of 136 skin images). The moisture-retaining property of the skin and subjective evaluation score of the skin fineness in 5-point scale for each case were also obtained in advance as a gold standard (their mean and SD were 35.15 +/- 3.22 (μS) and 3.45 +/- 1.17, respectively). We extracted a total of 107 image features from each image and built linear regression models for estimating abovementioned criteria with a stepwise feature selection. The developed model for estimating the skin moisture achieved the MSE of 1.92 (μS) with 6 selected parameters, while the model for skin fineness achieved that of 0.51 scales with 7 parameters under the leave-one-out cross validation. We confirmed the developed models predicted the moisture-retaining property and fineness of the skin appropriately with only captured image.

  8. Preliminary Observations from the 2014 Sand Dunes Experiment

    Science.gov (United States)

    2014-10-01

    2014 Sand Dunes Experiment by Christopher W. Miller, Ching-Sang Chiu, D. Benjamin Reeder, Ying-Jang Yang, Linus Chiu, and Chi-Fang Chen...COVERED (From-To) June 2014 4. TITLE AND SUBTITLE Preliminary Observations from the 2014 Sand Dunes Experiment 5a. CONTRACT NUMBER 5b. GRANT NUMBER...position of the Department of Defense or the U.S. Government 14. ABSTRACT The Sand Dunes 2014 experiment was international US – Taiwan

  9. Preliminary results of noise radar experiments

    Science.gov (United States)

    Malanowski, Mateusz; Contartese, Clara; Maslikowski, Lukasz; Baczyk, Marcin; Kulpa, Krzysztof

    2009-06-01

    The paper describes the first results of noise radar experiments carried out at Warsaw University of Technology. The radar system was built with Commercial Off-The-Shelf (COTS) components: log-periodic antennas, an arbitrary waveform generator and a two-channel spectrum analyzer. The radar operated in the continuous-wave mode, and the aim was to detect moving targets in the received signal. The paper shows the system setup as well as the numerical results obtained from the recorded signals.

  10. Metabolic Control with Insulin Pump Therapy: Preliminary Experience

    Directory of Open Access Journals (Sweden)

    Shang-Ren Hsu

    2008-07-01

    Conclusion: Our preliminary experience demonstrated the effectiveness of insulin pump therapy for both type 1 and type 2 diabetic patients. The reduction in their HbA1C values was both statistically and clinically significant. This treatment should be considered for patients poorly controlled by subcutaneous insulin injection therapy.

  11. Preliminary results of the echo-seeding experiment at SLAC

    Energy Technology Data Exchange (ETDEWEB)

    Xiang, D.; Colby, E.; Ding, Y.; Dunning, M.; Frederico, J.; Gilevich, S.; Hast, C.; Jobe, K.; McCormick, D.; Nelson, J.; Raubenheimer, T.O.; Soong, K.; Stupakov, G.; Szalata, Z.; Walz, D.; Weathersby, S.; Woodley, M.; Corlett, J.; Qiang, J.; Penn, G.; Prestemon, S.; Schlueter, R.; Venturini, M.; Wan, W.; Pernet, P-L.

    2010-05-23

    ECHO-7 is a proof-of-principle echo-enabled harmonic generation FEL experiment in the Next Linear Collider Test Accelerator (NLCTA) at SLAC. The experiment aims to generate coherent radiation at 318 nm and 227 nm, which are the 5th and 7th harmonic of the infrared seed laser. In this paper we present the preliminary results from the commissioning run of the completed experimental setup which started in April 2010.

  12. Percutaneous aspiration thromboembolectomy: a preliminary experience.

    Science.gov (United States)

    Murray, J G; Brown, A L; Wilkins, R A

    1994-08-01

    Percutaneous aspiration thromboembolectomy (PAT) is a radiological alternative to surgical embolectomy or thrombolysis in the treatment of acute arterial thromboembolic disease. We report our experience in eight patients aged 63-83 years (mean 71 years). Indications were graft thrombosis (1) or emboli from atrial fibrillation (3), abdominal aneurysm (2) or proximal angioplasty (2). PAT was performed at 10 arterial sites; common iliac (1), profunda femoris (1), superficial femoral (2), femoro-popliteal graft (1), popliteal (2) and arteries of the trifurcation (3). PAT was used as an adjunct to thrombolysis or angioplasty in five patients and as the sole procedure in three patients. It was successful in six patients (seven sites) with mean ABI rising from 0.4 pre- to 0.8 post-procedure. Two of the failures required amputations. One of these was a completely thrombosed dacron femoro-popliteal graft with poor run-off, and the second case had a failed surgical embolectomy prior to amputation. There were no major complications, and no mortality on follow-up at 1 month. PAT is a useful adjunct to thrombolysis and balloon angioplasty in the radiological treatment of acute thromboembolic disease. In patients in whom thrombolysis is contraindicated, it offers an alternative to surgical embolectomy.

  13. Charge generation associated with liquid spraying in tank cleaning and comparable processes - preliminary experiments

    Science.gov (United States)

    Blum, Carsten; Losert, Oswald F. J.

    2015-10-01

    The BG RCI has initiated investigations in order to improve the data basis for assessing the ignition hazard by electrostatic charging processes associated with the spraying of liquids. On the base of preliminary experiments, we established procedures for measurements of electric field strength and charging current in the presence of aerosol particles. Results obtained with three different nozzle types, variation of pressure and with built-in deflecting plate are presented.

  14. Preliminary results from the MINERvA experiment

    Energy Technology Data Exchange (ETDEWEB)

    Harris, Deborah A.; /Fermilab

    2011-11-01

    The MINERvA experiment, operating since 2009 in the NuMI neutrino beam line at Fermilab, has collected neutrino and antineutrino scattering data on a variety of nuclear targets. The detector is designed to identify events originating in plastic scintillator, lead, carbon, iron, water, and liquid helium. The goal of the experiment is to measure inclusive and exclusive cross sections for neutrino and antineutrino with much greater precision than previous experiments. We present preliminary kinematic distributions for charged current quasi-elastic scattering and other processes.

  15. Establishment of preliminary regulatory network of TRPV1 and related cytokines

    Directory of Open Access Journals (Sweden)

    Jianhua Zhang

    2017-03-01

    Full Text Available Our purpose was to investigate the regulatory mechanism of TRPV1 and related cytokines on children bronchial asthma. TRPV1 mRNA level and two SNP genotypes of children in case group and control group were detected by real-time quantitative PCR. Western blot and ELISA were used to measure the levels of cytokines like IgE, IL-2, etc. Their correlations were analyzed by Logistic regression and KEGG analysis. Moreover, tertiary structure of protein and miRNA binding sites were also predicted by online tools. Case group was obviously different from control group in TRPV1 mRNA level, the two SNP genotypes distribution and the related cytokines levels. Logistic regression analysis further demonstrated that TRPV1 mRNA level, EOS, IL-4 and IL-5 may be risk factors for children bronchial asthma. And based on that, the preliminary regulatory network of children bronchial asthma was drawn. What’s more, mutation of rs4790521 and rs4790522 in TRPV1 gene both induced its corresponding miRNA binding site’s change. The preliminary regulatory network of TRPV1 and related cytokines on children bronchial asthma established in this study provides certain theoretical basis for pathogenesis and treatment of children bronchial asthma.

  16. Establishment of a P-glycoprotein substrate screening model and its preliminary application

    Institute of Scientific and Technical Information of China (English)

    Yi Wang; Jiang Cao; Su Zeng

    2004-01-01

    AIM: To establish a high P-glycoprotein (P-gp) expressing cell line as a model for studying drug absorption and distribution, and to explore the preliminary application of this screening model.METHODS: A full-length MDR1 cDNA fragment in plasmid pMDRA1 was first subcloned into plasmid pET28a(+), then MDR1 cDNA was cut from the recombinant plasmid with double-digestion and ligated into the mammalian expression vector pcDNA3.1(+). The recombinant plasmid pcDNA3.1(+)/MDR1 was transfected into breast cancer cell line Bcap37using the Superfect transfection reagent. Several stably transfected clones were obtained after selection with G418.Real-time fluorescent quantitative RT- PCR and Western blot methods were used to detect the expression of P-gp, and the cellular location of the expressed protein was determined by immunohistochemical staining. Drug sensitivity assay was used to evaluate the biological function of expressed P-gp.Concentration of quercetin in cells was determined by highperformance liquid chromatography (HPLC).RESULTS: The recombinant plasmid was confirmed to be inserted in the correct orientation by restrictive enzyme digestion and DNA sequencing. Real-time fluorescent quantitative RT-PCR showed a higher level of P-cp mRNA in transfected cells compared to that in the control cells, and the Western blot result also indicated that P-gp expression in transfected cells was higher than that in control cells. The immunohistochemical staining showed that the expressed P-gp was localized on cell membranes. Drug sensitivity assay showed that the IC50 for adriamycin and colchicine of the transfected cells was higher than that of the control cells.The concentration of quercetin in model cells was lower than that in control cells by HPLC. After P-gp inhibitor verapamil was administered, the concentration of quercetin in model cells was increased.CONCLUSION: A high P-gp expressing ceil line can be established, which could provide a suitable in vitro model system for

  17. Preliminary Study on the Establishment of Regulatory Infrastructure for a Commercial SMART Licensing

    Energy Technology Data Exchange (ETDEWEB)

    Yune, Young Gill; Roh, Kyung Wan; Kang, Dong Gu; Kim, Hho Jung; Jo, Jong Chull [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2007-10-15

    The SMART, an integral type of PWR with the capacity of 330MWth, has been developed for multi-purposes such as seawater desalination, ship propulsion, and district heating in Korea since early 1990s. The basic design of the SMART had been completed in 2002. For the demonstration of the safety and performance of the SMART, a project to construct a 1/5 scaled-down prototype reactor with capacity of 65MWth, called as SMART-P(SMART Pilot Plant), has been performed from 2002 to 2006. However, in 2006, the project to construct the SMART-P was replaced with a preliminary project to develop a commercial SMART in order to advance commercialization of the SMART. Since the SMART is the first commercial reactor adopting the integral design concept and new system/components such as passive residual heat removal system, canned motor pump, and helical tube steam generator in Korea, some verification tests need to be performed to demonstrate the safety and performance of the SMART. Also, since several new design computer codes that have not yet been confirmed by the regulatory body are expected to be used in the design, some validation tests should be performed to demonstrate their applicability for important accident phenomena. In order to carry out the SMART development project satisfactorily and to prevent any undesirable delay of licensing process, it is necessary to establish a well-planned verification test program in advance through the early identification of the scope and items of the verification tests. Also, the issues for which either policy decision-makings or detailed technical evaluations are needed should be identified in an early stage of design, and the regulatory positions for the issues should be provided either timely or in advance. Advance identification of regulatory requirements/guides to be amended or newly developed enables to provide regulatory directions for such items in the early stage of design. The objective of this paper is to introduce the current

  18. The "SCORPION" experiment onboard the International Space Station. Preliminary results.

    Science.gov (United States)

    Borisov, V; Deshevaya, E; Grachov, E; Grigoryan, O; Tchurilo, I; Tsetlin, V

    2003-01-01

    The "SCORPION" program onboard the Russian Segment (RS) of the International Space Station (ISS) is designed to carry out complex research of the effects of the nar-Earth space parameters on the conditions under which various experiments and operations are being conducted. Special attention in this program was paid to the biological objects onboard the orbital station, e.g. it was found that variation in the number of colony forming units (micromicets and bacteria) correlates with the solar activity and the absorbed dose. The "SCORPION" experiment onboard the RS ISS started in January 2002. It was designed to measure the following parameters inside the space absorbed doses in different places inside the RS ISS, the fluxes of energetic charged particles, neutrons and gamma-quanta; the vectors of the magnetic field and low-frequency electromagnetic waves. At the same time the growth of micromicets on the samples of various materials was studied. The description of the "SCORPION" experiment and the preliminary results obtained onboard the RS ISS in 2002 are presented.

  19. Calibration Study and Preliminary Results of PRad Experiment

    Science.gov (United States)

    Levillain, Maxime; PRad Collaboration

    2016-09-01

    The latest measurements of the proton radius through muonic hydrogen Lamb shift show a discrepancy of 7 σ from a global analysis of standard hydrogen Lamb shift and elastic ep -scattering. In order to understand this proton radius puzzle, the PRad experiment successfully took in last June some elastic ep -scattering data at very low Q2 (2 .10-4 to 10-1 GeV2) with very accurate angle and energy measurements to minimize the systematic uncertainties. Before measuring the cross-sections that will be used to extract the electromagnetic form factor GE(Q2) and the proton radius, a very careful calibration of the electromagnetic calorimeter (HyCal) must be performed to get a good energy resolution and separate ep -events from M øller events especially at low angle. We will present an extended study of the electromagnetic calorimeter calibration of this experiment as well as some preliminary results on ep - and ee -scattering processes extracted from the data. The PRad experiment is supported in part by NSF MRI Award PHY-1229153.

  20. Experiences gained by establishing the IAMG Student Chapter Freiberg

    Science.gov (United States)

    Ernst, Sebastian M.; Liesenberg, Veraldo; Shahzad, Faisal

    2013-04-01

    The International Association for Mathematical Geosciences (IAMG) Student Chapter Freiberg was founded in 2007 at the Technische Universität Bergakademie Freiberg (TUBAF) in Germany by national and international graduate and undergraduate students of various geoscientific as well as natural science disciplines. The major aim of the IAMG is to promote international cooperation in the application and use of Mathematics in Geosciences research and technology. The IAMG encourages all types of students and young scientists to found and maintain student chapters, which can even receive limited financial support by the IAMG. Following this encouragement, generations of students at TUBAF have build up and established a prosperous range of activities. These might be an example and an invitation for other young scientists and institutions worldwide to run similar activities. We, some of the current and former students behind the student chapter, have organised talks, membership drives, student seminars, guest lectures, several short courses and even international workshops. Some notable short courses were held by invited IAMG distinguished lecturers. The topics included "Statistical analysis in the Earth Sciences using R - a language and environment for statistical computing and graphics", "Geomathematical Natural Resource Modeling" and "Introduction to Geostatistics for Environmental Applications and Natural Resources Evaluation: Basic Concepts and Examples". Furthermore, we conducted short courses by ourselves. Here, the topics included basic introductions into MATLAB, object oriented programming concepts for geoscientists using MATLAB and an introduction to the Keyhole Markup Language (KML). Most of those short courses lasted several days and provided an excellent and unprecedented teaching experience for us. We were given credit by attending students for filling gaps in our university's curriculum by providing in-depth and hands-on tutorials on topics, which were merely

  1. Design, integration and preliminary results of the IXV Catalysis experiment

    Science.gov (United States)

    Viladegut, Alan; Panerai, F.; Chazot, O.; Pichon, T.; Bertrand, P.; Verdy, C.; Coddet, C.

    2016-08-01

    The CATalytic Experiment (CATE) is an in-flight demonstration of catalysis effects at the surface of thermal protection materials. A high-catalytic coating was applied over the baseline ceramic material on the windward side of the intermediate experimental vehicle (IXV). The temperature jump due to different catalytic activities was detected during re-entry through measurements made with near-surface thermocouples on the windward side of the vehicle. The experiment aimed at contributing to the development and validation of gas/surface interaction models for re-entry applications. The present paper summarizes the design of CATE and its integration on the windward side of the IXV. Results of a qualification campaign at the Plasmatron facility of the von Karman Institute for Fluid Dynamics are presented. They provided an experimental evidence of the temperature jump at the low-to-high catalytic interface of the heat shield under aerothermal conditions relevant to the actual IXV flight. These tests also gave confidence so that the high-catalytic patch would not endanger the integrity of the vehicle and the safety of the mission. A preliminary assessment of flight data from the thermocouple measurements shows consistency with results of the qualification tests.

  2. Establishment of the model of vascular endothelial cell membrane chromatography and its preliminary application

    Institute of Scientific and Technical Information of China (English)

    LI YiPing; HE LangChong

    2007-01-01

    A model of vascular endothelial cell membrane chromatography was established by using an ECV304 cell membrane stationary phase (ECV304 CMSP) prepared by immobilizing the ECV304 cell membrane onto the surface of silica carrier. The surface and chromatographic characteristics of ECV304 CMSP were studied. The active component from Caulophyllum robustum was screened by using the model of vascular endothelial cell membrane chromatography. The interaction between the active component and membrane receptor was determined by using a replace experiments. The effect of the active component was tested by using tube formation of ECV304 cell. The results indicated that the model of ECV304 cell membrane chromatograph (ECV304 CMC) can stimulate the interaction between drug and receptor in vitro and the retention characteristics of taspine as active component was similar to that of model molecule in the model of ECV304 CMC. And therefore, taspine acted on VEGFR2 and inhibited the tube formation of ECV304 cell induced by VEGF. This model can be used to screen definite active component as a screening model.

  3. Preliminary results of the XR2-1 experiment

    Energy Technology Data Exchange (ETDEWEB)

    Gauntt, R.O.; Helmick, P.H. [Sandia National Labs., Albuquerque, NM (United States); Humphries, L. [SAIC, Albuquerque, NM (United States)

    1996-03-01

    The XR2-1 (Ex-Reactor) experiment, investigating metallic core-melt relocation in boiling water reactor geometry, was performed on October 12, 1995, following two previous simpler XR1-series tests in August and November of 1993. The XR2-1 test made use of a highly detailed replication of the lower region of the BWR core, including the control blade and channel box structures, fuel rods, fuel canister nosepieces, control blade velocity limiter, and fuel support pieces, in order to investigate a key core melt progression uncertainty for BWR Station Blackout type accidents. The purpose of this experiment program is to examine the behavior of downward-draining molten metallic core materials in a severe reactor accident in a dry BWR core, and to determine conditions under which the molten materials drain out of the core region, or freeze to form blockages in the lower portion of the core. In the event that the draining metallic materials do not form stable blockages in the lower core region, and instead erode the lower core structures such as the lower core plate, then the subsequent core melt progression processes may proceed quite differently than was observed in the TMI-2 accident, with correspondingly different impact on vessel loading and vessel release behavior. The results of the Ex-Reactor tests are preliminary. All of the tests conducted have shown a significant degree of channel box destruction induced by the draining control blade materials. The XR2-1 test further showed that the draining zircaloy melt causes significant disruption of the fuel rod geometry. All of the tests have shown tendencies to form interim blockages as the melts temporarily freeze, but that these blockages re-melt, assisted by eutectic interactions, resulting in the sudden draining of accumulated metallic melt pools.

  4. China ADS sub-critical experimental assembly-Venus-1 and preliminary experiment

    Institute of Scientific and Technical Information of China (English)

    SHI Yongqian; ZHANG Wei; CAO Jian; QUAN Yanhui; LUO Huangda; WU Xiaofei; XIA Pu; LUO Zhanglin; ZHAO Zhixiang; DING Dazhao; LI Yiguo; ZHU Qinfu; XIA Haihong; LI Jien

    2007-01-01

    China's accelerator-driven sub-critical system (ADS) sub-critical experimental assembly--Venus-1 and the preliminary experiment is presented. The core of Venus-1 is a coupled one of a fast neutron zone and a thermal neutron zone. The fast neutron zone is at the centre of the core and formed by natural uranium fuel. A fast neutron spectrum field can be produced in the fast neutron zone and used for the transmutation of minor actinides (Mas). The thermal neutron zone surrounds the fast neutron zone and is formed by low-enriched uranium fuel. It is a fission zone. An epithermal neutron zone between the fast neutron zone and the thermal neutron zone can be established for the transmutation of longlived fission products (LLFP). On July 18, 2005, the first fuel element was loaded into the Venus-Ⅰ sub-critical assembly and some preliminary experiments about the subcritical neutronics were performed. The Venus-1 can be driven by an Am-Be source or other steady neutron source (Cf-252, D-D reaction and D-T reaction) to study the effect of the external neutron source with different energies or a D-T pulsed neutron source on the dynamic characteristics.

  5. Establishing an Adult Epilepsy Diet Center: Experience, efficacy and challenges.

    Science.gov (United States)

    Cervenka, Mackenzie C; Henry, Bobbie J; Felton, Elizabeth A; Patton, Katlyn; Kossoff, Eric H

    2016-05-01

    Over 250 medical centers worldwide offer ketogenic diets to children with epilepsy; however, access to these therapies has been extremely limited for adults until recent years. We examine our 5-year experience creating and implementing a dedicated Adult Epilepsy Diet Center designed to provide adults with epilepsy access to ketogenic diets. Outpatients seen at the Johns Hopkins Adult Epilepsy Diet Center from August 2010 thru September 2015 age 18years and older were enrolled in a prospective open-label observational study. Patients that also enrolled in ongoing clinical diet trials were excluded from this study. Participant demographics, diet type, urine and/or serum ketones, laboratory studies, seizure frequency, diet duration, reason for discontinuing diet therapy, and side effects were recorded. A subgroup analysis of participants that met International League Against Epilepsy (ILAE) criteria for drug-resistant epilepsy (DRE) and were treated de novo with a Modified Atkins Diet (MAD) was performed to compare outcomes with the current literature regarding efficacy of other antiseizure treatments for DRE. Two hundred and twenty-nine adults attended the Adult Epilepsy Diet Center, and 168 met inclusion criteria. Two-thirds (n=113, 67%) were women with an age range of 18-86years at the initial visit. Thirty-five participants (21%, n=133) were already on a therapeutic diet while 79% (n=133) were naïve to diet therapy at the time of the initial visit. Diet-naïve participants were typically prescribed MAD (n=130, 98%), unless unable to intake adequate oral nutrition, in which case they were prescribed KD (n=1) or a combination of oral MAD and ketogenic formula (n=2). Twenty-nine of 130 (22%) participants prescribed MAD elected not to start or were lost to follow-up, and 101 (78%) began MAD. A subgroup analysis was performed on one hundred and six participants naïve to diet therapy that met International League Against Epilepsy criteria for DRE, were able to

  6. BIOMEX (Biology and Mars Experiment): Preliminary results on Antarctic black cryptoendolithic fungi in ground based experiments

    OpenAIRE

    C. Pacelli; Selbmann, L.; S. Onofri; de Vera, J.P.P.

    2014-01-01

    The main goal for astrobiologists is to find traces of present or past life in extraterrestrial environment or in meteorites. Biomolecules, such as lipids, pigments or polysaccharides, may be useful to establish the presence of extant or extinct life (Simoneit, B et al., 1998). BIOMEX (Biology and Mars Experiment) aims to measure to what extent biomolecules, such as pigments and cellular components, preserve their stability under space and Mars-like conditions. The experiment has just been la...

  7. Preliminary experience with laparoscopic cholecystectomy in a nigerian teaching hospital.

    Science.gov (United States)

    Afuwape, O O; Akute, O O; Adebanjo, A T

    2012-01-01

    Presently many centers have facilities for laparoscopic surgery in Nigeria, but the practice is just evolving in most of these centers. This article presents the preliminary experience of the endoscopic surgery unit (general surgery) at the University College Hospital Ibadan Nigeria. The University College Hospital is the premier Nigerian teaching hospital and is located in the south-western part of the country. All the patients who had laparoscopic cholecystectomy at the University College Hospital between June 2009 and January 2011 were included in this study. The patients' demographic data, diagnosis, results of investigations and intra-operative findings were obtained from the records. Additional information extracted from the records was the duration of surgery, complications, outcome and discharge periods. There were thirteen patients over the twenty month period consisting of twelve females and one male. The age range was twenty six to sixty seven years with a mean of 44.6 years. The duration of surgery ranged from 90 to 189 minutes with a mean of 124 minutes. There were two complications. These were adhesive bowel obstruction and common bile duct injury. The duration of admission ranged from four to thirty two days with a mean of 7.53SD ± 8.5 days. There was one conversion to open surgery due to intra-operative gallbladder perforation with consequent dispersal of multiple gall stones within the peritoneal cavity. The common bile duct injury was diagnosed four days following surgery for which a choledochojejunostomy was done after initial conservative treatment. There was no mortality. Laparoscopic surgery is feasible in Nigeria and is likely to show increasing popularity among patients and surgeons. A careful patient selection protocol is necessary for an acceptable success rate with minimal complications. Our protocol of patient selection eliminated the need for intra-operative common bile duct exploration which requires expensive instruments. However, to

  8. Preliminary Design of a Pendulum Experiment for Searching for a Lorentz-Violation Signal

    CERN Document Server

    Shao, Cheng-Gang; Tan, Yu-Jie

    2016-01-01

    This work mainly presents a preliminary design for a pendulum experiment with both the source mass and the test mass in a striped pattern to amplify the Lorentz-violation signal, since the signal is sensitive to edge effects.

  9. Establishing Normative Values for the Barnett Balance Assessment Tool: A Preliminary Study

    Directory of Open Access Journals (Sweden)

    Monica L. Cercone MSOTS

    2014-04-01

    Full Text Available The purpose of this study was to establish normative data for the Barnett Balance Assessment (BBA for individuals ages 18-70+ years. The BBA is a newly developed assessment tool that may address limitations present in other assessments currently used to detect balance deficits. The BBA was administered to 141 participants who had no history of medical issues that could impact balance. A review of the normative data collected indicated little variation in total assessment scores in the age categories of 18-29, 30-39, and 40-49, due to the presence of a ceiling effect. Variations existed in scores among participants in the remaining age categories (50-59, 60-69, and 70+. These findings may imply that the BBA has its greatest discriminative power in assessing individuals with impaired balance, and/or that the BBA is not sensitive enough to detect differences in individuals with mild balance impairments. The researchers suggest future studies be conducted with the BBA to establish norms with populations with known orthopedic or neurological conditions that may impair balance. Results of these studies could then be compared with the baseline data gathered in this study to determine the BBA’s usefulness in detecting balance impairments with clinical populations.

  10. Effect of oxygen manipulations on benthic foraminifera: A preliminary experiment

    Digital Repository Service at National Institute of Oceanography (India)

    Panchang, R.; Nigam, R.; Linshy, V.; Rana, S.S.; Ingole, B.S.

    marine protists, which have a great potential to detect ecological stress at a very early stage. Due to their high fossilization potential, an understanding of the ecology of foraminifera allows interpretations of the past benthic environmental...’. Many soft-shelled forms also exist, but have not been considered in the present study as they have no fossilization potential and thereby of no geological significance. This is a preliminary report and only presents the effect of oxygen...

  11. Preliminary Experiments with XKaapi on Intel Xeon Phi Coprocessor

    OpenAIRE

    Ferreira Lima, Joao Vicente; Broquedis, Francois; Gautier, Thierry; Raffin, Bruno

    2013-01-01

    International audience; This paper presents preliminary performance comparisons of parallel applications developed natively for the Intel Xeon Phi accelerator using three different parallel programming environments and their associated runtime systems. We compare Intel OpenMP, Intel CilkPlus and XKaapi together on the same benchmark suite and we provide comparisons between an Intel Xeon Phi coprocessor and a Sandy Bridge Xeon-based machine. Our benchmark suite is composed of three computing k...

  12. A preliminary evaluation model for reservoir hydrocarbon-generating potential established based on dissolved hydrocarbons in oilfield water

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    A large number of oilfield water samples were analyzed in this work. Research on the relationship between the concentrations and distribution of dissolved hydrocarbons sug gested that the contents and composition of dissolved hydrocarbons varied with the hydrocar bon-generating potential of reservoirs. The concentrations of dissolved hydrocarbons were low in dry layers, water layers and gas-water layers, but high in gas reservoirs and oil reservoirs, especially in gas reservoirs with condensed oil. Series of carbon-number alkanes were usually absent in oilfield water from dry layers, water layers and gas-water layers but abundant in oil field water from oil-water reservoirs, gas reservoirs and oil reservoirs, whose carbon numbers varied most widely in oil reservoirs and least in gas reservoirs. A preliminary evaluation model for reservoir hydrocarbon-generating potential was established based on the characteristics of dissolved hydrocarbons in oilfield water to assist hydrocarbon exploration.

  13. Establishment and Preliminary Application of a Rapid Fluorescent Focus Inhibition Test (RFFIT) for Rabies Virus

    Institute of Scientific and Technical Information of China (English)

    Pengcheng Yu; Xinjun Lv; Xinxin Shen; Qing Tang; Guodong Liang

    2013-01-01

    The World Health Organization (WHO) standard assay for determining levels of the rabies virus neutralization antibody (RVNA) is the rapid fluorescent focus inhibition test (RFFIT),which is used to evaluate the immunity effect after vaccination against rabies.For RFFIT,CVS-11 was used as the challenge virus,BSR cells as the adapted cells,and WHO rabies immunoglobulin (WHO STD) as the reference serum in this study.With reference to WHO and Pasteur RFFIT procedures,a micro-RFFIT procedure adapted to our laboratory was produced,and its specificity and reproducibility were tested.We tested levels of RVNA in human serum samples after immunization with different human rabies vaccines (domestic purified Vero cell rabies vaccine (PVRV) and imported purified chick embryo cell vaccine (PCECV)) using different regimens (Zagreb regimen and Essen regimen).We analyzed the levels of RVNA,and compared the immune efficacy of domestic PVRV and imported PCECV using different immunization regimens.The results showed that the immune efficacy of domestic PVRV using the Zagreb regimen was as good as that of the imported PCECV,but virus antibodies were generated more rapidly with the Zagreb regimen than with the Essen regimen.The RFFIT procedure established in our laboratory will enhance the comprehensive detection ability of institutions involved in rabies surveillance in China.

  14. A simple strategy to establish preliminary engine cylinder geometry for optimum combustion

    Energy Technology Data Exchange (ETDEWEB)

    Harish Kumar, R. [Sri Siddhartha Inst. of Technology, Karnataka (India); Antony, A.J. [Sahyadri Inst. of Technology, Mangalore, Karnataka (India)

    2009-07-01

    The design of modern spark ignition engines presents a challenge for automotive engineers in terms of striking the right combination of engine operating parameters and geometry. Most modern spark ignition engines have a compression ratio in the range 8 to 11 and the engine geometry is dictated by the choice of the bore/stroke (B/Ls) ratio in addition to various other design considerations such as the location and size of valves and location of spark plugs. Small engines generally have a B/Ls ratio ranging from 0.7 to 1.3 while large stationary engines have a ratio of less than 0.7. For a given displacement volume, a longer stroke allows for smaller bore which results in less surface area in the combustion chamber with a correspondingly smaller heat loss, which increases thermal efficiency within the combustion chamber. However the longer stroke results in higher piston speed and higher friction losses which reduces the brake power output of the engine. If the stroke is shortened, the bore must be increased which reduces the friction losses but increases the heat transfer losses. This paper presented a simple thermodynamics approach based on one dimensional thermodynamic model of the combustion chamber to establish the appropriate B/Ls ratio depending on the operating conditions of the engine such as its compression ratio, speed, and fuel equivalence ratios, in conjunction with a nearly full fledged simulation program for optimum combustion in spark ignition engines. The paper described the engine test rig as well as the experimental procedure. The development of the mathematical model was also explained. It was concluded that there is a significant relationship between the compression ratio of the engine and the B/Ls ratio. These valves must match for optimum combustion and optimum specific power output. 10 refs., 1 tab., 5 figs.

  15. An overview of the Tokamak Physics Experiment vacuum vessel preliminary design

    Energy Technology Data Exchange (ETDEWEB)

    Rocco, R.E. [Raytheon Engineers and Constructors, Inc., Princeton, NJ (United States)

    1995-12-31

    The mission of the Tokamak Physics Experiment (TPX) Project is to develop the scientific basis for a compact and continuously operating tokamak fusion reactor. The vacuum vessel, which consists of a double walled torus, ports and supports, is a major element of the TPX machine. This paper provides an overview of the vacuum vessel preliminary design work. The design of the vacuum vessel is being carried out by an industrial team under subcontract to the Princeton Plasma Physics Laboratory. The respective work scopes of this team are discussed. The role of concurrent engineering is presented in the context of this design-build subcontract. A discussion of the engineering requirements, material selection rationale and vacuum vessel configuration is provided. Titanium 6Al-4V will be used to fabricate the vacuum vessel. Significant material concerns were identified with the use of titanium; hydrogen embrittlement and the effects of borated water were the major issues. A research and development (R and D) program was established to resolve these material issues as well as to develop the vessel weld details. A comprehensive analytical effort was established to perform the structural and thermal analysis of the vessel. Design details of the vessel, supports, ports, and flanges are presented.

  16. AGC-1 Experiment and Final Preliminary Design Report

    Energy Technology Data Exchange (ETDEWEB)

    Robert L. Bratton; Tim Burchell

    2006-08-01

    This report details the experimental plan and design as of the preliminary design review for the Advanced Test Reactor Graphite Creep-1 graphite compressive creep capsule. The capsule will contain five graphite grades that will be irradiated in the Advanced Test Reactor at the Idaho National Laboratory to determine the irradiation induced creep constants. Seven other grades of graphite will be irradiated to determine irradiated physical properties. The capsule will have an irradiation temperature of 900 C and a peak irradiation dose of 5.8 x 10{sup 21} n/cm{sup 2} [E > 0.1 MeV], or 4.2 displacements per atom.

  17. Determinants of plant establishment success in a multispecies introduction experiment with native and alien species.

    Science.gov (United States)

    Kempel, Anne; Chrobock, Thomas; Fischer, Markus; Rohr, Rudolf Philippe; van Kleunen, Mark

    2013-07-30

    Determinants of plant establishment and invasion are a key issue in ecology and evolution. Although establishment success varies substantially among species, the importance of species traits and extrinsic factors as determinants of establishment in existing communities has remained difficult to prove in observational studies because they can be confounded and mask each other. Therefore, we conducted a large multispecies field experiment to disentangle the relative importance of extrinsic factors vs. species characteristics for the establishment success of plants in grasslands. We introduced 48 alien and 45 native plant species at different seed numbers into multiple grassland sites with or without experimental soil disturbance and related their establishment success to species traits assessed in five independent multispecies greenhouse experiments. High propagule pressure and high seed mass were the most important factors increasing establishment success in the very beginning of the experiment. However, after 3 y, propagule pressure became less important, and species traits related to biotic interactions (including herbivore resistance and responses to shading and competition) became the most important drivers of success or failure. The relative importance of different traits was environment-dependent and changed over time. Our approach of combining a multispecies introduction experiment in the field with trait data from independent multispecies experiments in the greenhouse allowed us to detect the relative importance of species traits for early establishment and provided evidence that species traits--fine-tuned by environmental factors--determine success or failure of alien and native plants in temperate grasslands.

  18. Preliminary results of the scientific experiments on the Kosmos-936 biosatellite

    Science.gov (United States)

    1977-01-01

    The scientific equipment and experiments on the Kosmos-936 biosatellite are described, including various ground controls and the lab unit for studies at the descent vehicle landing site. Preliminary results are presented of the physiological experiment with rats, biological experiments with drosophila and higher and lower plants, and radiation physics and radiobiology studies for the planning of biological protection on future space flights. The most significant conclusion from the preliminary data is that rats tolerate space flight better with an artificial force of gravity.

  19. Zero-gravity cloud physics laboratory: Experiment program definition and preliminary laboratory concept studies

    Science.gov (United States)

    Eaton, L. R.; Greco, E. V.

    1973-01-01

    The experiment program definition and preliminary laboratory concept studies on the zero G cloud physics laboratory are reported. This program involves the definition and development of an atmospheric cloud physics laboratory and the selection and delineations of a set of candidate experiments that must utilize the unique environment of zero gravity or near zero gravity.

  20. Interactions between piscivores, zooplanktivores and zooplankton in submerged macrophytes : Preliminary observations from enclosure and pond experiments

    DEFF Research Database (Denmark)

    Jacobsen, Lene; Perrow, M.R.; Landkildehus, F.

    1997-01-01

    behavioural changes of zooplanktivores has received little attention, even though this may be an important mechanism in enhancing the stability of submerged macrophytes in shallow lakes. Preliminary observations from an unreplicated large-scale field enclosure experiment and a replicated pond experiment...

  1. Preliminary Studies for Three Experiments at Treiman-Yang Criterion

    Science.gov (United States)

    Kres, I. V.; Kondratyev, V. N.; Cherubini, S.; Spitaleri, C.

    2016-05-01

    Nuclear reactions with three bodies in their final state may proceed through different reaction mechanisms. The Feynman graph technique has been widely used to describe such reactions. However, it is very difficult in general to select the graphs that dominate in given process. The Treiman-Yang criterion is one of the most powerful experimental tests for verifying the pole approximation prediction when describing a quasi-free reaction mechanism. We propose the theoretical study of the H2(B10, α Be7)ns, H1(B11, α1α2)αs, He3(Be9, α1α2)αs reactions at different energies. The preliminary study helps to check the existence of a QF channel by using the TY creterion.

  2. Preliminary results from the {sup 51}Cr neutrino source experiment in GALLEX

    Energy Technology Data Exchange (ETDEWEB)

    Hampel, W.; Heusser, G.; Kiko, J. [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany)] [and others

    1996-09-01

    The GALLEX collaboration performed a second {sup 51}Cr neutrino source experiment during fall 1995. The full results from this second source experiment will not be available before the end of 1996. Meanwhile, we present a short description and preliminary results in this informal note. The (preliminary) value of the activity obtained form direct measurements has been found equal to (68.7 {+-}0.7) PBq (with 1-sigma error). This value, which is about 10% higher than the activity of the first source, was achieved by optimizing the irradiation conditions in the Silo{acute e} reactor and doing a longer irradiation of the enriched chromium. Preliminary results show that the ratio, R, of the radiochemically determined activity from {sup 71}Ge counting (57.1 {+-} PBq) to the directly measured activity is (0.83 {+-} 0.10). The combined value of R for the two source experiments is (0.92 {+-} 0.08).

  3. Kinetics experiments and bench-scale system: Background, design, and preliminary experiments

    Energy Technology Data Exchange (ETDEWEB)

    Rofer, C.K.

    1987-10-01

    The project, Supercritical Water Oxidation of Hazardous Chemical Waste, is a Hazardous Waste Remedial Actions Program (HAZWRAP) Research and Development task being carried out by the Los Alamos National Laboratory. Its objective is to obtain information for use in understanding the basic technology and for scaling up and applying oxidation in supercritical water as a viable process for treating a variety of DOE-DP waste streams. This report gives the background and rationale for kinetics experiments on oxidation in supercritical water being carried out as a part of this HAZWRAP Research and Development task. It discusses supercritical fluid properties and their relevance to applying this process to the destruction of hazardous wastes. An overview is given of the small emerging industry based on applications of supercritical water oxidation. Factors that could lead to additional applications are listed. Modeling studies are described as a basis for the experimental design. The report describes plug flow reactor and batch reactor systems, and presents preliminary results. 28 refs., 4 figs., 5 tabs.

  4. Preliminary Experiments on the Propagation of Plastic Deformation

    Science.gov (United States)

    2013-04-25

    Burnh:l.m Kelly Assist:J.nt to the Chief 2 Defense and Offense • • .. , . R E _S __ 1 RIC TED ., Preface ’ . The work described ~n this...variance with t he t heoreticall ;J- obta i ned curves and , hence, needs f~ther explanation. The object of the experiment s des cribed in t hi s...quite well with the experiments . The shape of t he pl3.stic wave is at some variance with the theor et i cally obta i ned curves. A.s shown by

  5. The MathScheme Library: Some Preliminary Experiments

    CERN Document Server

    Carette, Jacques; Jeremic, Filip; Maccio, Vincent; O'Connor, Russell; Tran, Quang M

    2011-01-01

    We present some of the experiments we have performed to best test our design for a library for MathScheme, the mechanized mathematics software system we are building. We wish for our library design to use and reflect, as much as possible, the mathematical structure present in the objects which populate the library.

  6. Opportunity of objective account of the colorimetric procedure using benzidine indicative at establishing the preliminary presence of blood on the material evidences

    Directory of Open Access Journals (Sweden)

    A. V. Konovalenko

    2015-01-01

    Full Text Available The article presents a modification of the colorimetric method for the preliminary establishment of presence of blood in the stainson the material evidences using benzidine test. The proposed modification is accompanied by photometric accounting and computer processing of the results. Performance, objectivity, as well as other features and advantages of this method when used in forensic practice are described in detail.

  7. Preliminary results of solar constant observations with the SOLCON experiment on ATLAS-1

    Science.gov (United States)

    Crommelynck, D.; Domingo, V.; Barkstrom, B.; Lee, R. B., II; Donaldson, J.; Telljohann, U; Warren, L.; Fichot, A.

    1994-01-01

    A brief description is given of the Solar Constant (SOLCAN) experiment on Atmospheric Laboratory for Applications and Science (ATLAS) 1, its scientific and technical objectives, as well as its measurement principle and its on board chronology of operations. A preliminary value of the solar constant during the third solar operation of the mission is also provided.

  8. THE MORPHOLOGICAL BASIS FOR OLFACTORY PERCEPTION OF STEROIDS DUING AGONISTIC BEHAVIOR IN LOBSTER: PRELIMINARY EXPERIMENTS

    Science.gov (United States)

    The morphological basis for olfactory perception of steroids during agonistic behavior in lobsters: preliminary experiments. Borsay Horowitz, DJ1, Kass-Simon, G2, Coglianese, D2, Martin, L2, Boseman, M2, Cromarty, S3, Randall, K3, Fini, A.3 1US EPA, NHEERL, ORD, Atlantic Ecology...

  9. Redesigning pictographs for patients with low health literacy and establishing preliminary steps for delivery via smart phones

    Science.gov (United States)

    2015-01-01

    Background: Pictographs (or pictograms) have been widely utilized to convey medication related messages and to address nonadherence among patients with low health literacy. Yet, patients do not always interpret the intended messages on commonly used pictographs correctly and there are questions how they may be delivered on mobile devices. Objective: Our objectives are to refine a set of pictographs to use as medication reminders and to establish preliminary steps for delivery via smart phones. Methods: Card sorting was used to identify existing pictographs that focus group members found “not easy” to understand. Participants then explored improvements to these pictographs while iterations were sketched in real-time by a graphic artist. Feedback was also solicited on how selected pictographs might be delivered via smart phones in a sequential reminder message. The study was conducted at a community learning center that provides literacy services to underserved populations in Seattle, WA. Participants aged 18 years and older who met the criteria for low health literacy using S-TOFHLA were recruited. Results: Among the 45 participants screened for health literacy, 29 were eligible and consented to participate. Across four focus group sessions, participants examined 91 commonly used pictographs, 20 of these were ultimately refined to improve comprehensibility using participatory design approaches. All participants in the fifth focus group owned and used cell phones and provided feedback on preferred sequencing of pictographs to represent medication messages. Conclusion: Low literacy adults found a substantial number of common medication label pictographs difficult to understand. Participative design processes helped generate new pictographs, as well as feedback on the sequencing of messages on cell phones, that may be evaluated in future research. PMID:27382421

  10. Redesigning pictographs for patients with low health literacy and establishing preliminary steps for delivery via smart phones

    Directory of Open Access Journals (Sweden)

    Wolpin SE

    2016-06-01

    Full Text Available Background: Pictographs (or pictograms have been widely utilized to convey medication related messages and to address nonadherence among patients with low health literacy. Yet, patients do not always interpret the intended messages on commonly used pictographs correctly and there are questions how they may be delivered on mobile devices. Objective: Our objectives are to refine a set of pictographs to use as medication reminders and to establish preliminary steps for delivery via smart phones. Methods: Card sorting was used to identify existing pictographs that focus group members found “not easy” to understand. Participants then explored improvements to these pictographs while iterations were sketched in real-time by a graphic artist. Feedback was also solicited on how selected pictographs might be delivered via smart phones in a sequential reminder message. The study was conducted at a community learning center that provides literacy services to underserved populations in Seattle, WA. Participants aged 18 years and older who met the criteria for low health literacy using S-TOFHLA were recruited. Results: Among the 45 participants screened for health literacy, 29 were eligible and consented to participate. Across four focus group sessions, participants examined 91 commonly used pictographs, 20 of these were ultimately refined to improve comprehensibility using participatory design approaches. All participants in the fifth focus group owned and used cell phones and provided feedback on preferred sequencing of pictographs to represent medication messages. Conclusion: Low literacy adults found a substantial number of common medication label pictographs difficult to understand. Participative design processes helped generate new pictographs, as well as feedback on the sequencing of messages on cell phones, that may be evaluated in future research.

  11. Redesigning pictographs for patients with low health literacy and establishing preliminary steps for delivery via smart phones.

    Science.gov (United States)

    Wolpin, Seth E; Nguyen, Juliet K; Parks, Jason J; Lam, Annie Y; Morisky, Donald E; Fernando, Lara; Chu, Adeline; Berry, Donna L

    2016-01-01

    Pictographs (or pictograms) have been widely utilized to convey medication related messages and to address nonadherence among patients with low health literacy. Yet, patients do not always interpret the intended messages on commonly used pictographs correctly and there are questions how they may be delivered on mobile devices. Our objectives are to refine a set of pictographs to use as medication reminders and to establish preliminary steps for delivery via smart phones. Card sorting was used to identify existing pictographs that focus group members found "not easy" to understand. Participants then explored improvements to these pictographs while iterations were sketched in real-time by a graphic artist. Feedback was also solicited on how selected pictographs might be delivered via smart phones in a sequential reminder message. The study was conducted at a community learning center that provides literacy services to underserved populations in Seattle, WA. Participants aged 18 years and older who met the criteria for low health literacy using S-TOFHLA were recruited. Among the 45 participants screened for health literacy, 29 were eligible and consented to participate. Across four focus group sessions, participants examined 91 commonly used pictographs, 20 of these were ultimately refined to improve comprehensibility using participatory design approaches. All participants in the fifth focus group owned and used cell phones and provided feedback on preferred sequencing of pictographs to represent medication messages. Low literacy adults found a substantial number of common medication label pictographs difficult to understand. Participative design processes helped generate new pictographs, as well as feedback on the sequencing of messages on cell phones, that may be evaluated in future research.

  12. Preliminary experience with laparoscopic surgery in Ile-Ife, Nigeria.

    Science.gov (United States)

    Adisa, A O; Arowolo, O A; Salako, A A; Lawal, O O

    2009-12-01

    This study presents a pioneer experience with laparoscopic operations in a General Surgical unit of the Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria. Consecutive patients who had laparoscopic operations from April through December 2008 were prospectively studied. Following clinical diagnosis, initial diagnostic laparoscopy was undertaken in all patients, followed by therapeutic open or laparoscopic procedures. All procedures were done under general anaesthesia. Duration of operation and outcome including complications were recorded. In all, there were 12 patients (8 males, 4 females), aged 15 to 50 years. Eight patients had clinical diagnoses of acute appendicitis, one each had undetermined right lower abdominal pain suspected ectopic gestation, adhesive intestinal obstruction and metastatic liver disease. The first 4 patients with inflammed appendix confirmed at laparoscopy had open appendicectomy. Of the next cohort of 5 patients, laparoscopic appendicectomy was completed in four but converted to open procedure in one. Normal findings were noted in the lady with suspected ectopic gestation. Laparoscopic adhesiolysis was done for adhesive intestinal obstruction while a laparoscopic liver biopsy was done for the patient with metastatic liver disease. Operative time ranged from 55-105 minutes with marked reduction in operation time as confidence and experience grew. No intraoperative complication was observed but one patient had superficial port site infection postoperatively. We conclude that with good patient selection and some improvisation, laparoscopic general surgical operations are feasible with acceptable outcome even in a poor resource setting.

  13. Preliminary skyshine calculations for the Poloidal Diverter Tokamak Experiment

    Science.gov (United States)

    Nigg, D. W.; Wheeler, F. J.

    1981-01-01

    A calculational model is presented to estimate the radiation dose, due to the skyshine effect, in the control room and at the site boundary of the Poloidal Diverter Experiment (PDX) facility at Princeton University which requires substantial radiation shielding. The required composition and thickness of a water-filled roof shield that would reduce this effect to an acceptable level is computed, using an efficient one-dimensional model with an Sn calculation in slab geometry. The actual neutron skyshine dose is computed using a Monte Carlo model with the neutron source at the roof surface obtained from the slab Sn calculation, and the capture gamma dose is computed using a simple point-kernel single-scatter method. It is maintained that the slab model provides the exact probability of leakage out the top surface of the roof and that it is nearly as accurate as and much less costly than multi-dimensional techniques.

  14. A PRELIMINARY EXPERIMENT ON DENITRIFICATION OF WASTE LANDFILL LEACHATE

    Science.gov (United States)

    Wada, Nariaki; Nakamichi, Tamihiro; Yagi, Masahiro; Matsumoto, Toshihide; Kugimiya, Akikazu; Michioku, Kohji

    A laboratory experiment on denitrification was carried out in order to reduce nitrogen load from municipal landfill leachate. Nitrogen was efficiently removed by feeding sludge of the leachate pond into the tanks, which could activate denitrification bacteria. Although inorganic reducing agent such as iron powder was not able to make the whole water mass anoxic, denitrification took place by supplying organic matters such as methanol, hydrogen feeding agent, etc.. It is considered that small amount of anoxic water film produced on surfaces of container and carriers might contribute to denitrification, although the bulk water is kept aerobic. It is found that organic matters contained in the leachate is so insufficient that nitrification liquid circulation does not work well for denitrification.

  15. Preliminary Results of the Echo-Seeding Experiment ECHO-7 at SLAC

    Energy Technology Data Exchange (ETDEWEB)

    Xiang, D.; Colby, E.; Ding, Y.; Dunning, M.; Frederico, J.; Gilevich, S.; Hast, C.; Jobe, K.; McCormick, D.; Nelson, J.; Raubenheimer, T.O.; Soong, K.; Stupakov, G.; Szalata, Z.; Walz, D.; Weathersby, S.; Woodley, M.; /SLAC; Corlett, J.; Qiang, J.; Penn, G.; Prestemon, S.; /LBL, Berkeley /LPHE, Lausanne

    2010-06-15

    ECHO-7 is a proof-of-principle echo-enabled harmonic generation FEL experiment in the Next Linear Collider Test Accelerator (NLCTA) at SLAC. The experiment aims to generate coherent radiation at 318 nm and 227 nm, which are the 5th and 7th harmonic of the infrared seed laser. In this paper we present the preliminary results from the commissioning run of the completed experimental setup which started in April 2010.

  16. Hydrogeological characterization of the Heletz Sands Reservoir, Heletz (Israel) as a preliminary step towards CO2 injection experiments

    Science.gov (United States)

    Bensabat, Jacob; Niemi, Auli; Tsang, Chin-Fu; Sharma, Prabhakar; Carrera, Jesus; Sauter, Martin; Tatomir, Alexandru; Ghergut, Julia; Pezard, Philippe; Edlman, Katriona; Brauchler, Ralf

    2013-04-01

    Hydrogeological characterization of the Heletz Sands Reservoir, Heletz (Israel) as a preliminary step towards CO2 injection experiments One the major components of the EU-FP7 funded MUSTANG project is to conduct a highly controlled series of CO2 injection experiments, aimed at determining field values of key CO2 trapping mechanisms such as dissolution and residual trapping and to establish a comprehensive and consistent dataset for model validation. Prior to injecting CO2 there is a need to achieve a sufficient degree of hydrogeological characterization of the reservoir. In what follows we present a sequence of hydrologic tests to be conducted at Heletz and their expected contribution to the understanding relevant hydrogeology. These include: 1) Chemical characterization of the formation fluid; 2) Flowing Fluid Electrical Conductivity log, aimed at determining the vertical variability of the reservoir permeability in the near well vicinity; 3) Water pulse and pumping tests, aimed at determining the reservoir scale hydraulic properties; 4) Thermal test, aimed at determining the value of the heat transfer coefficient from the reservoir to the borehole fluid, which is responsible for the heating of injected fluid in the borehole; 5) two-well injection and pumping of water and tracers test, in order to determine the impact of heterogeneity on the hydraulic parameters and to identify preferential flow paths in the reservoir. This paper presents the design and planning of the experiments, the results obtained in field and a preliminary interpretation.

  17. Preliminary experiments: High-energy alpha PIXE in archaeometry

    Energy Technology Data Exchange (ETDEWEB)

    Dupuis, Thomas, E-mail: T.Dupuis@ulg.ac.b [Centre Europeen d' Archeometrie, Atomique et Spectroscopie, Universite de Liege, Sart Tilman B15, B-4000 Liege (Belgium); Institut de Physique Nucleaire, Atomique et Spectroscopie, Universite de Liege, Sart Tilman B15, B-4000 Liege (Belgium); Chene, G.; Mathis, F. [Centre Europeen d' Archeometrie, Atomique et Spectroscopie, Universite de Liege, Sart Tilman B15, B-4000 Liege (Belgium); Institut de Physique Nucleaire, Atomique et Spectroscopie, Universite de Liege, Sart Tilman B15, B-4000 Liege (Belgium); Marchal, A.; Philippe, M.; Garnir, H.-P. [Institut de Physique Nucleaire, Atomique et Spectroscopie, Universite de Liege, Sart Tilman B15, B-4000 Liege (Belgium); Strivay, D. [Centre Europeen d' Archeometrie, Atomique et Spectroscopie, Universite de Liege, Sart Tilman B15, B-4000 Liege (Belgium); Institut de Physique Nucleaire, Atomique et Spectroscopie, Universite de Liege, Sart Tilman B15, B-4000 Liege (Belgium)

    2010-06-15

    This paper describes the work realized at the 'Centre Europeen d'Archeometrie' to highlight the utility of high-energy alpha PIXE in the particular field of archaeometry and to introduce the developments done and to be done to complete the knowledge of high-energy alpha PIXE. It starts with the comparison of the yield and the noise background between several alpha particle beams and the comparison between alpha particle and proton beams on different thick and thin references. After, this paper depicts the developments done at the 'Institut de Physique Nucleaire, Atomique et Spectroscopie' to perform such high-energy experiments, first on standards and later on cultural heritage objects. Moreover, it introduces the problematics of such beams for the quantification in PIXE by the intermediary of the knowledge of the ionization and X-ray production cross-sections and also the developments done to answer to this serious lack in the databases.

  18. Mitchell′s technique for epispadias repair: Our preliminary experience

    Directory of Open Access Journals (Sweden)

    Sarin Yogesh

    2006-01-01

    Full Text Available Aim: We present here experience of a single surgeon with Mitchell′s procedure for correction of epispadias. Materials and Methods: Nine boys (mean age 5½ years, range 9 months to 16 years underwent Mitchell′s repair in Department of Pediatric Surgery over a period of 5½ (September 1999 to March 2005 for correction of epispadias. Six of these patients had come for the second stage of exstrophy-epispadias repair after primary bladder closure; the other three had incontinent penopubic epispadias. Results: The penis was cosmetically acceptable as regards to size, glans shape and peno-pubic angle in all the patients. However, there was a high incidence of penopubic fistula (44%. These patients with penopubic fistula also required postoperative urethral dilatations, at times repeated. One of the common factors to these subset patients was their younger age when Mitchell′s urethroplasty was performed. Limitations: The series is descriptive in nature, short in numbers and does not provide statistical comparison of Mitchell′s procedure with the previously done procedures. Conclusions: Mitchell′s complete penile disassembly technique for epispadias repair is more acceptable anatomical procedure that results in near-pendulous penis. However, when performed at young age, it is fraught with the complication of penopubic fistula similar to that as seen with Cantwell-Ransley′s procedure. Mitchell′s procedure creates a hypospadiac meatus initially and the meatal advancement is required as for any other distal penile/coronal hypospadias.

  19. Smart Ultrasound Remote Guidance Experiment (SURGE) Preliminary Findings

    Science.gov (United States)

    Hurst, Victor; Dulchavsky, Scott; Garcia, Kathleen; Sargsyan, Ashot; Ebert, Doug

    2009-01-01

    To date, diagnostic quality ultrasound images were obtained aboard the International Space Station (ISS) using the ultrasound of the Human Research Facility (HRF) rack in the Laboratory module. Through the Advanced Diagnostic Ultrasound in Microgravity (ADUM) and the Braslet-M Occlusion Cuffs (BRASLET SDTO) studies, non-expert ultrasound operators aboard the ISS have performed cardiac, thoracic, abdominal, vascular, ocular, and musculoskeletal ultrasound assessments using remote guidance from ground-based ultrasound experts. With exploration class missions to the lunar and Martian surfaces on the horizon, crew medical officers will necessarily need to operate with greater autonomy given communication delays (round trip times of up to 5 seconds for the Moon and 90 minutes for Mars) and longer periods of communication blackouts (due to orbital constraints of communication assets). The SURGE project explored the feasibility and training requirements of having non-expert ultrasound operators perform autonomous ultrasound assessments in a simulated exploration mission outpost. The project aimed to identify experience, training, and human factors requirements for crew medical officers to perform autonomous ultrasonography. All of these aims pertained to the following risks from the NASA Bioastronautics Road Map: 1) Risk 18: Major Illness and Trauna; 2) Risk 20) Ambulatory Care; 3) Risk 22: Medical Informatics, Technologies, and Support Systems; and 4) Risk 23: Medical Skill Training and Maintenance.

  20. Preliminary experience with biodegradable implants for fracture fixation

    Directory of Open Access Journals (Sweden)

    Dhillon Mandeep

    2008-01-01

    Full Text Available Background: Biodegradable implants were designed to overcome the disadvantages of metal-based internal fixation devices. Although they have been in use for four decades internationally, many surgeons in India continue to be skeptical about the mechanical strength of biodegradable implants, hence this study. Materials and Methods: A prospective study was done to assess the feasibility and surgeon confidence level with biodegradable implants over a 12-month period in an Indian hospital. Fifteen fractures (intra-articular, metaphyseal or small bone fractures were fixed with biodegradable implants. The surgeries were randomly scheduled so that different surgeons with different levels of experience could use the implants for fixation. Results: Three fractures (one humeral condyle, two capitulum, were supplemented by additional K-wires fixation. Trans-articular fixator was applied in two distal radius and two pilon fractures where bio-pins alone were used. All fractures united, but in two cases the fracture displaced partially during the healing phase; one fibula due to early walking, and one radius was deemed unstable even after bio-pin and external fixator. Conclusions: Biodegradable -implants are excellent for carefully selected cases of intra-articular fractures and some small bone fractures. However, limitations for use in long bone fractures persist and no great advantage is gained if a "hybrid" composite is employed. The mechanical properties of biopins and screws in isolation are perceived to be inferior to those of conventional metal implants, leading to low confidence levels regarding the stability of reduced fractures; these implants should be used predominantly in fracture patterns in which internal fixation is subjected to minimal stress.

  1. Preliminary Experience with a New Total Distal Radioulnar Joint Replacement

    Science.gov (United States)

    Ewald, Timothy J.; Skeete, Kshamata; Moran, Steven L.

    2012-01-01

    resurfacing design may provide a means of decreasing pain and restoring DRUJ stability and motion following severe trauma, failed hemiarthroplasty, or failed Sauvé–Kapandji procedure. More experience is needed with this implant to confirm these initial encouraging results. The level of evidence for this study is IV (therapeutic, case series). PMID:23904976

  2. [Low field intra-operative magnetic resonance imaging for brain tumour surgery: preliminary experience].

    Science.gov (United States)

    Roldán, Pedro; García, Sergio; González, Josep; Reyes, Luis Alberto; Torales, Jorge; Valero, Ricard; Oleaga, Laura; Enseñat, Joaquim

    Intra-operative magnetic resonance imaging (iMRI) is a recently introduced tool in the most advanced neurosurgical operating rooms worldwide. We present our preliminary experience in brain tumour surgery with low field PoleStar N30® intraoperative MRI since its introduction in 2013 in the Barcelona Clinic Hospital. A prospective non-randomised study was conducted on cases operated on using iMRI and intention of complete removal up to October 2015. A record was made of the data as regards surgical times, resection rates, histological diagnosis, hospital stay, and survival rates during follow-up. The study included 50 patients, with a mean age of 55 years (±13.7), a preoperative mean Karnofsky of 92 (being 81 post-operatively), and a mean follow-up of 10.5 months (±6.5). There were 26% re-operations due to recurrence. High-grade gliomas were reported in 56%, low-grade gliomas in 24%, and 20% "Other" tumours. Overall hospital stay was 10 days (±4.5). Depending on the histologiacl diagnosis, the "Others" group had a longer hospital stay. Overall, there were 52% complete removal, 18% of maximum removals, and 30% of partial removals. The overall survival rates during follow-up was 84%. iMRI is a safe and effective tool for brain tumour surgery. Its use allows an increase in resection rates, and minimises post-operative complications. Its implementation involves an increase in surgical time, which improves with the characteristic learning curve. More studies are needed to establish its role in the long-term survival of patients. Copyright © 2016 Sociedad Española de Neurocirugía. Publicado por Elsevier España, S.L.U. All rights reserved.

  3. Muon-catalyzed fusion experiment target and detector system. Preliminary design report

    Energy Technology Data Exchange (ETDEWEB)

    Jones, S.E.; Watts, K.D.; Caffrey, A.J.; Walter, J.B.

    1982-03-01

    We present detailed plans for the target and particle detector systems for the muon-catalyzed fusion experiment. Requirements imposed on the target vessel by experimental conditions and safety considerations are delineated. Preliminary designs for the target vessel capsule and secondary containment vessel have been developed which meet these requirements. In addition, the particle detection system is outlined, including associated fast electronics and on-line data acquisition. Computer programs developed to study the target and detector system designs are described.

  4. The RPC-based IFR system at BaBar experiment preliminary results

    CERN Document Server

    Piccolo, D; Bagnasco, S; Baldini, R; Band, H R; Bionta, R; Buzzo, A; Calcaterra, A; Cavallo, N; Contri, R; Crosetti, G; De Nardo, Gallieno; De Sangro, R; Fabozzi, F; Falciai, D; Finocchiaro, G; Gatto, C; Johnson, J; Lista, L; Lo Vetere, M; Macri, M; Monge, R; Palano, A; Paolucci, P; Passaggio, S; Patrignani, C; Patteri, P; Peruzzi, I; Piccolo, M; Robutti, E; Santroni, A; Sciacca, C; Wright, D; Yu, Z; Zallo, A

    2002-01-01

    The IFR system is a RPC-based detector used to identify muons and neutral hadrons in the BaBar experiment at PEP II machine in SLAC. The RPC system can be used to reconstruct the trajectory of muons, pions and neutral hadrons interacting in the iron of the IFR. The different range and hit pattern allow to discriminate different particles crossing the IFR. An overview of the system design and the preliminary results on the IFR performances are reported.

  5. PET/MRI: a novel hybrid imaging technique. Major clinical indications and preliminary experience in Brazil.

    Science.gov (United States)

    Vitor, Taise; Martins, Karine Minaif; Ionescu, Tudor Mihai; Cunha, Marcelo Livorsi da; Baroni, Ronaldo Hueb; Garcia, Marcio Ricardo Taveira; Wagner, Jairo; Campos, Guilherme de Carvalho; Nogueira, Solange Amorim; Guerra, Elaine Gonçalves; Amaro, Edson

    2017-01-01

    In recent years, medical imaging with hybrid techniques has widely accepted and employed in clinical routine. PET/MRI offers significant advantages, including excellent contrast and resolution and reduced ionizing radiation, as compared to well-established PET/CT. Therefore, PET/MRI is a promising modality for oncologic imaging of some regions, such as brain, head and neck, liver and pelvis. This article set out to analyze clinical conditions that could benefit from PET/MRI imaging based on our caseload. The potential of PET/MRI to become the imaging modality of choice for assessment of neurologic and oncologic conditions associated with soft tissues is highlighted. Clinical aspects of PET/MRI and its application to clinical cases are illustrated with examples extracted from the authors' preliminary experience. RESUMO Nos últimos anos, imagens médicas com tecnologias híbridas tornaram-se amplamente aceitas e utilizadas na prática clínica. O PET/RM possui vantagens importantes, incluindo excelentes contrastes e resolução, e menor radiação ionizante, em comparação ao PET/TC. Por isto, é uma modalidade promissora para exames de imagem de pacientes oncológicos, para avaliar o cérebro, cabeça e pescoço, o fígado e a pelve. O objetivo deste artigo foi analisar as situações clínicas que se beneficiariam de exames de PET/RM a partir de uma casuística. Destacamos o potencial desta técnica se tornar o método de imagem de escolha para doenças neurológicas e oncológicas que envolvam partes moles. Os aspectos clínicos de PET/RM e sua aplicação aos casos clínicos são ilustrados com exemplos da experiência inicial dos autores.

  6. Gaslini's tracheal team: preliminary experience after one year of paediatric airway reconstructive surgery

    Directory of Open Access Journals (Sweden)

    Torre Michele

    2011-10-01

    Full Text Available Abstract Background congenital and acquired airway anomalies represent a relatively common albeit challenging problem in a national tertiary care hospital. In the past, most of these patients were sent to foreign Centres because of the lack of local experience in reconstructive surgery of the paediatric airway. In 2009, a dedicated team was established at our Institute. Gaslini's Tracheal Team includes different professionals, namely anaesthetists, intensive care specialists, neonatologists, pulmonologists, radiologists, and ENT, paediatric, and cardiovascular surgeons. The aim of this project was to provide these multidisciplinary patients, at any time, with intensive care, radiological investigations, diagnostic and operative endoscopy, reconstructive surgery, ECMO or cardiopulmonary bypass. Aim of this study is to present the results of the first year of airway reconstructive surgery activity of the Tracheal Team. Methods between September 2009 and December 2010, 97 patients were evaluated or treated by our Gaslini Tracheal Team. Most of them were evaluated by both rigid and flexible endoscopy. In this study we included 8 patients who underwent reconstructive surgery of the airways. Four of them were referred to our centre or previously treated surgically or endoscopically without success in other Centres. Results Eight patients required 9 surgical procedures on the airway: 4 cricotracheal resections, 2 laryngotracheoplasties, 1 tracheal resection, 1 repair of laryngeal cleft and 1 foreign body removal with cardiopulmonary bypass through anterior tracheal opening. Moreover, in 1 case secondary aortopexy was performed. All patients achieved finally good results, but two of them required two surgeries and most required endoscopic manoeuvres after surgery. The most complex cases were the ones who had already been previously treated. Conclusions The treatment of paediatric airway anomalies requires a dedicated multidisciplinary approach and a

  7. Fiscal year 1981 US corn and soybeans pilot preliminary experiment plan, phase 1

    Science.gov (United States)

    Livingston, G. P.; Nedelman, K. S.; Norwood, D. F.; Smith, J. H. (Principal Investigator)

    1981-01-01

    A draft of the preliminary experiment plan for the foreign commodity production forecasting project fiscal year 1981 is presented. This draft plan includes: definition of the phase 1 and 2 U.S. pilot objectives; the proposed experiment design to evaluate crop calendar, area estimation, and area aggregation components for corn and soybean technologies using 1978/1979 crop-year data; a description of individual sensitivity evaluations of the baseline corn and soybean segment classification procedure; and technology and data assessment in support of the corn and soybean estimation technology for use in the U.S. central corn belt.

  8. Promising and Established Investigators' Experiences Participating in the National Athletic Trainers' Association Foundation Research Mentor Program.

    Science.gov (United States)

    Nottingham, Sara L; Mazerolle, Stephanie M; Barrett, Jessica L

    2017-04-01

      Mentorship is a helpful resource for individuals who transition from doctoral student to tenure-track faculty member. The National Athletic Trainers' Association (NATA) Research & Education Foundation offers a Research Mentor Program to provide mentorship to promising investigators, particularly as they work to establish independent lines of research.   To gain the perspectives of promising and established investigators on their participation in the NATA Foundation Research Mentor Program.   Qualitative, phenomenological research.   Higher education institutions.   Seven promising investigators (5 women, 2 men) and 7 established investigators (2 women, 5 men), all of whom had completed the NATA Foundation Research Mentor Program. Data Collection and Analysis We developed and piloted intervi: ew guides designed to gain participants' perspectives on their experiences participating in the NATA Foundation Research Mentor Program. Semistructured telephone interviews were completed with each individual and transcribed verbatim. Data were analyzed using a phenomenological approach, and saturation was obtained. Trustworthiness was established with the use of member checking, multiple-analyst triangulation, and data-source triangulation.   Three themes emerged from the interviews: (1) motivation, (2) collaboration, and (3) resources. Participants were motivated to become involved because they saw the value of mentorship, and mentees desired guidance in their research. Participants believed that collaboration on a project contributed to a positive relationship, and they also desired additional program and professional resources to support novice faculty.   Promising and established investigators should be encouraged to engage in mentoring relationships to facilitate mentees' research agendas and professional development. The NATA Foundation and athletic training profession may consider providing additional resources for novice faculty, such as training on

  9. The NASA Juncture Flow Experiment: Goals, Progress, and Preliminary Testing (Invited)

    Science.gov (United States)

    Rumsey, Christopher L.; Neuhart, Danny H.; Kegerise, Michael A.

    2016-01-01

    NASA has been working toward designing and conducting a juncture flow experiment on a wing-body aircraft configuration. The experiment is planned to provide validation-quality data for CFD that focuses on the onset and progression of a separation bubble near the wing-body juncture trailing edge region. This paper describes the goals and purpose of the experiment. Although currently considered unreliable, preliminary CFD analyses of several different configurations are shown. These configurations have been subsequently tested in a series of "risk-reduction" wind tunnel tests, in order to help down-select to a final configuration that will attain the desired flow behavior. The risk-reduction testing at the higher Reynolds number has not yet been completed (at the time of this writing), but some results from one of the low-Reynolds-number experiments are shown.

  10. Establishment of technical prerequisites for cell irradiation experiments with laser-accelerated electrons.

    Science.gov (United States)

    Beyreuther, E; Enghardt, W; Kaluza, M; Karsch, L; Laschinsky, L; Lessmann, E; Nicolai, M; Pawelke, J; Richter, C; Sauerbrey, R; Schlenvoigt, H P; Baumann, M

    2010-04-01

    , along with the optimized setup, to a beam diameter of 35 mm, sufficient for the irradiation of common cell culture vessels. The corresponding maximum dose inhomogeneity over the beam spot was less than 10% for all irradiated samples. At cell position, the electrons posses a mean kinetic energy of 13.6 MeV, a bunch length of about 5 ps (FWHM), and a mean pulse dose of 1.6 mGy/bunch. Cross correlations show clear linear dependencies for the online recorded accumulated bunch charges, pulse doses, and pulse numbers on absolute doses determined with EBT-1 films. Hence, the established monitoring system is suitable for beam control and a dedicated dose delivery. Additionally, reasonable day-to-day stable and reproducible properties of the electron beam were achieved. Basic technical prerequisites for future cell irradiation experiments with ultrashort pulsed laser-accelerated electrons were established at the JETI laser system. The implemented online control system is suitable to compensate beam intensity fluctuations and the achieved accuracy of dose delivery to the cells is sufficient for radiobiological cell experiments. Hence, systematic in vitro cell irradiation experiments can be performed, being the first step toward clinical application of laser-accelerated particles. Further steps, including the transfer of the established methods to experiments on higher biological systems or to other laser-based particle accelerators, will be prepared.

  11. Establishing a cGMP pancreatic islet processing facility: the first experience in Iran.

    Science.gov (United States)

    Larijani, Bagher; Arjmand, Babak; Amoli, Mahsa M; Ao, Ziliang; Jafarian, Ali; Mahdavi-Mazdah, Mitra; Ghanaati, Hossein; Baradar-Jalili, Reza; Sharghi, Sasan; Norouzi-Javidan, Abbas; Aghayan, Hamid Reza

    2012-12-01

    It has been predicted that one of the greatest increase in prevalence of diabetes will happen in the Middle East bear in the next decades. The aim of standard therapeutic strategies for diabetes is better control of complications. In contrast, some new strategies like cell and gene therapy have aimed to cure the disease. In recent years, significant progress has occurred in beta-cell replacement therapies with a progressive improvement of short-term and long term outcomes. In year 2005, considering the impact of the disease in Iran and the promising results of the Edmonton protocol, the funding for establishing a current Good Manufacturing Practice (cGMP) islet processing facility by Endocrinology and Metabolism Research Center was approved by Tehran University of Medical Sciences. Several islet isolations were performed following establishment of cGMP facility and recruitment of all required equipments for process validation and experimental purpose. Finally the first successful clinical islet isolation and transplantation was performed in September 2010. In spite of a high cost of the procedure it is considered beneficial and may prevent long term complications and the costs associated with secondary cares. In this article we will briefly describe our experience in setting up a cGMP islet processing facility which can provide valuable information for regional countries interested to establish similar facilities.

  12. An evaluation of the Positive Emotional Experiences Scale: A preliminary analysis

    Directory of Open Access Journals (Sweden)

    Rene van Wyk

    2016-04-01

    Full Text Available Orientation: The positive organisational behaviour movement emphasises the advantages of psychological strengths in business. The psychological virtues of positive emotional experiences can potentially promote human strengths to the advantages of business functioning and the management of work conditions. This is supported by Fredrickson’s broaden-and-build theory that emphasises the broadening of reactive thought patterns through experiences of positive emotions.Research purpose: A preliminary psychometric evaluation of a positive measurement of dimensions of emotional experiences in the workplace, by rephrasing the Kiefer and Barclay Toxic Emotional Experiences Scale.Motivation for the study: This quantitative Exploratory Factor Analysis investigates the factorial structure and reliability of the Positive Emotional Experiences Scale, a positive rephrased version of the Toxic Emotional Experiences Scale.Research approach, design and method: This Exploratory Factor Analysis indicates an acceptable three-factor model for the Positive Emotional Experiences Scale. These three factors are: (1 psychological recurrent positive state, (2 social connectedness and (3 physical refreshed energy, with strong Cronbach’s alphas of 0.91, 0.91 and 0.94, respectively.Main findings: The three-factor model of the Positive Emotional Experiences Scale provides a valid measure in support of Fredrickson’s theory of social, physical and psychological endured personal resources that build positive emotions.Practical/Managerial implications: Knowledge gained on positive versus negative emotional experiences could be applied by management to promote endured personal resources that strengthen positive emotional experiences.Contribution/value-add: The contribution of this rephrased Positive Emotional Experiences Scale provides a reliable measure of assessment of the social, physical and endured psychological and personal resources identified in Fredrickson’s broaden

  13. Spinel dissolution via addition of glass forming chemicals. Results of preliminary experiments

    Energy Technology Data Exchange (ETDEWEB)

    Fox, K. M. [Savannah River Site (SRS), Aiken, SC (United States); Johnson, F. C. [Savannah River Site (SRS), Aiken, SC (United States)

    2015-11-01

    Increased loading of high level waste in glass can lead to crystallization within the glass. Some crystalline species, such as spinel, have no practical impact on the chemical durability of the glass, and therefore may be acceptable from both a processing and a product performance standpoint. In order to operate a melter with a controlled amount of crystallization, options must be developed for remediating an unacceptable accumulation of crystals. This report describes preliminary experiments designed to evaluate the ability to dissolve spinel crystals in simulated waste glass melts via the addition of glass forming chemicals (GFCs).

  14. Preliminary experience with Piccolo Composite™, a radiolucent distal fibula plate, in ankle fractures.

    Science.gov (United States)

    Caforio, Marco; Perugia, Dario; Colombo, Massimiliano; Calori, Giorgio Maria; Maniscalco, Pietro

    2014-12-01

    The radiolucent plate has many advantageous properties in the treatment of complex ankle fractures, particularly trimalleolar fractures. Surgeons may sometimes have difficulty observing the posterior malleolus after synthesis of lateral malleolus with a traditional plate because common materials of conventional plates are not radiolucent. In this study, the authors highlight the importance of the radiolucent property in the treatment of ankle fractures and describe their preliminary experience with a carbon fibre-reinforced polyetheretherketone distal fibula plate, with good results at 4 months' follow-up and no signs of tissue inflammatory reaction.

  15. Percutaneous pulmonary valve implantation in a single artery branch: A preliminary experience

    Institute of Scientific and Technical Information of China (English)

    Massimo; Chessa; Gianfranco; Butera; Luca; Giugno; Angelo; Micheletti; Diana; G; Negura; Mario; Carminati

    2015-01-01

    To describe preliminary experience of percutaneous pulmonary valve implantation, in a single pulmonary branch position. Two procedures in 2 patients from a single center are described, where implantation of percutaneous valves within a single pulmonary artery branch was technically successful. The procedural indication was pulmonary valve regurgitation and/or residual stenosis. The 2 patients were symptomatic. An Edwards Sapien? valve(Patient 1), and a Medtronic Melody? valve(Patient 2) were implanted. Both pts were discharged with an excellent valve function. In this report it is underlined that this modality is technically feasible and may be considered an option in patients with congenital heart defect under special circumstances.

  16. Low-dose fetal CT for evaluation of severe congenital skeletal anomalies: preliminary experience

    Energy Technology Data Exchange (ETDEWEB)

    Victoria, Teresa; Epelman, Monica; Johnson, Ann M.; Kramer, Sandra; Jaramillo, Diego [Children' s Hospital of Philadelphia, Diagnostic Imaging, Philadelphia, PA (United States); Bebbington, Michael [Children' s Hospital of Philadelphia, Center for Fetal Diagnosis and Treatment, Philadelphia, PA (United States); Wilson, R.D. [University of Calgary, Obstetrics and Gynecology, Calgary (Canada)

    2012-01-15

    Congenital skeletal abnormalities compose a heterogeneous and complex group of conditions that affect bone growth and development and result in various anomalies in shape and size of the skeleton. Prenatal sonographic diagnosis of these anomalies is challenging because of the relative rarity of each skeletal dysplasia, the multitude of differential diagnoses encountered when the bony abnormalities are identified, lack of precise molecular diagnosis and the fact that many of these disorders have overlapping features and marked phenotypic variability. The following review is a preliminary summary of our experience at the Children's Hospital of Philadelphia (CHOP) using low-dose fetal CT in the evaluation of severe fetal osseous abnormalities. (orig.)

  17. FOREIGN AND DOMESTIC EXPERIENCE OF INTEGRATING CLOUD COMPUTING INTO PEDAGOGICAL PROCESS OF HIGHER EDUCATIONAL ESTABLISHMENTS

    Directory of Open Access Journals (Sweden)

    Nataliia A. Khmil

    2016-01-01

    Full Text Available In the present article foreign and domestic experience of integrating cloud computing into pedagogical process of higher educational establishments (H.E.E. has been generalized. It has been stated that nowadays a lot of educational services are hosted in the cloud, e.g. infrastructure as a service (IaaS, platform as a service (PaaS and software as a service (SaaS. The peculiarities of implementing cloud technologies by H.E.E. in Ukraine and abroad have been singled out; the products developed by the leading IT companies for using cloud computing in higher education system, such as Microsoft for Education, Google Apps for Education and Amazon AWS Educate have been reviewed. The examples of concrete types, methods and forms of learning and research work based on cloud services have been provided.

  18. Establishing second trimester abortion services: experiences in Nepal, Viet Nam and South Africa.

    Science.gov (United States)

    Hyman, Alyson G; Baird, Traci L; Basnett, Indira

    2008-05-01

    This paper describes experiences and lessons learned about how to establish safe second trimester abortion services in low-resource settings in the public health sector in three countries: Nepal, Viet Nam and South Africa. The key steps involved include securing the necessary approvals, selecting abortion methods, organising facilities, obtaining necessary equipment and supplies, training staff, setting up and managing services, and ensuring quality. It may take a number of months to gain the necessary approvals to introduce or expand second trimester services. Advocacy efforts are often required to raise awareness among key governmental and health system stakeholders. Providers and their teams require thorough training, including values clarification; monitoring and support following training prevents burn-out and ensures quality of care. This paper shows that good quality second trimester abortion services are achievable in even the most low-resource settings. Ultimately, improvements in second trimester abortion services will help to reduce abortion-related morbidity and mortality.

  19. Establishment and Implementation of a Required Medication Therapy Management Advanced Pharmacy Practice Experience

    Science.gov (United States)

    Gilliam, Eric; Thompson, Megan; Griend, Joseph Vande

    2017-01-01

    Objective. To develop a community pharmacy-based medication therapy management (MTM) advanced pharmacy practice experience (APPE) that provides students with skills and knowledge to deliver entry-level pharmacy MTM services. Design. The University of Colorado Skaggs School of Pharmacy & Pharmaceutical Sciences (SSPPS) partnered with three community pharmacy chains to establish this three-week, required MTM APPE. Students completed the American Pharmacists Association MTM Certificate Course prior to entering the APPE. Students were expected to spend 90% or more of their time at this experience working on MTM interventions, using store MTM platforms. Assessment. All 151 students successfully completed this MTM APPE, and each received a passing evaluation from their preceptor. Preceptor evaluations of students averaged above four (entry-level practice) on a five-point Likert scale. The majority of students reported engagement in MTM services for more than 80% of the time on site. Students’ self-reporting of their ability to perform MTM interventions improved after participation in the APPE. Conclusion. The SSPPS successfully implemented a required MTM APPE, preparing students for entry-level delivery of MTM services. PMID:28381896

  20. Rayleigh-Taylor Instability within Sediment Layers Due to Gas Retention: Preliminary Theory and Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Gauglitz, Phillip A.; Wells, Beric E.; Buchmiller, William C.; Rassat, Scot D.

    2013-03-21

    In Hanford underground waste storage tanks, a typical waste configuration is settled beds of waste particles beneath liquid layers. The settled beds are typically composed of layers, and these layers can have different physical and chemical properties. One postulated configuration within the settled bed is a less-dense layer beneath a more-dense layer. The different densities can be a result of different gas retention in the layers or different degrees of settling and compaction in the layers. This configuration can experience a Rayleigh-Taylor (RT) instability where the less dense lower layer rises into the upper layer. Previous studies of gas retention and release have not considered potential buoyant motion within a settle bed of solids. The purpose of this report is to provide a review of RT instabilities, discuss predictions of RT behavior for sediment layers, and summarize preliminary experimental observations of RT instabilities in simulant experiments.

  1. Investigation of fracture-matrix interaction: Preliminary experiments in a simple system

    Energy Technology Data Exchange (ETDEWEB)

    Foltz, S.D. [New Mexico Univ., Albuquerque, NM (United States). Dept. of Physics and Astronomy; Tidwell, V.C.; Glass, R.J.; Sobolik, S.R. [Sandia National Labs., Albuquerque, NM (United States)

    1992-12-31

    Paramount to the modeling of unsaturated flow and transport through fractured porous media is a clear understanding of the processes controlling fracture-matrix interaction. As a first step toward such an understanding, two preliminary experiments have been performed to investigate the influence of matrix imbibition on water percolation through unsaturated fractures in the plane normal to the fracture. Test systems consisted of thin slabs of either tuff or an analog material cut by a single vertical fracture into which a constant fluid flux was introduced. Transient moisture content and solute concentration fields were imaged by means of x-ray absorption. Flow fields associated with the two different media were significantly different owing to differences in material properties relative to the imposed flux. Richards` equation was found to be a valid means of modeling the imbibition of water into the tuff matrix from a saturated fracture for the current experiment.

  2. [The use of nitric oxide during transport of newborns with critical respiratory insufficiency: own experience, preliminary report].

    Science.gov (United States)

    Ziebiński, Marek; Walas, Wojciech

    2002-01-01

    This preliminary report presents author's experience with inhaled nitric oxide during transport of newborns with critical respiratory insufficiency. The theoretical basis, indications and contraindications as well as principles of administration during transport are described. The required equipment and some technical aspects are discussed. A short preview of performed transportations is given. Preliminary data show, that use of NO during transport is very helpful in children with critical respiratory insufficiency.

  3. An Irish Experience in Establishing and Evaluating an Intern Led Teaching Programme.

    Science.gov (United States)

    Jenkinson, A; Kelleher, E; Moneley, D; Offiah, G

    2017-03-10

    Near-Peer Teaching is a relatively new and expanding area of medical education. The benefit to medical students has been demonstrated in numerous contexts around the world. Our aim was to establish a structured Intern-Led Teaching (ILT) programme in the context of an Irish Intern Training Network affiliated to an Irish Medical School. We then sought to evaluate the success of this programme. Seventy interns were enrolled in the ILT programme and completed a Train the Trainer course involving teaching methods and skills of effective feedback. Following this, the intern tutors delivered several one-hour teaching sessions in small groups to final year medical students on a weekly basis. At the end of each teaching block, a feedback questionnaire was distributed to participating students to evaluate their experiences of this new teaching modality. Tutorial topics were varied. They included clinical examination, history taking, prescribing, and emergencies. Eighty-one percent of students found the intern-led tutorials to be beneficial compared to tutorials run by more senior doctors. Additionally, students felt that with intern led tutorials they could ask questions they otherwise would not. There was a more comfortable environment, and information taught was considered more relevant. A significant number of students felt less nervous about the final medical examinations after the intern-led tutorials. The establishment of a structured intern-led teaching programme was well received by final year medical students. This project shows that interns are a valuable teaching resource in the medical school and should be included in medical schools' curricula.

  4. Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC - the Hot Start experience

    Directory of Open Access Journals (Sweden)

    Paul A. De Sousa

    2017-04-01

    eTOC: The report focuses on the EBiSC experience of rapidly establishing an operational capacity to procure, bank and distribute a foundational collection of established hiPSC lines. It validates the feasibility and defines the challenges of harnessing and integrating the capability and productivity of centres across Europe using commonly available resources currently in the field.

  5. Experience of Delphi technique in the process of establishing consensus on core competencies.

    Science.gov (United States)

    Raghav, Pankaja Ravi; Kumar, Dewesh; Bhardwaj, Pankaj

    2016-01-01

    The Department of Community Medicine and Family Medicine (CMFM) has been started as a new model for imparting the components of family medicine and delivering health-care services at primary and secondary levels in all six newly established All India Institute of Medical Sciences (AIIMS), but there is no competency-based curriculum for it. The paper aims to share the experience of Delphi method in the process of developing consensus on core competencies of the new model of CMFM in AIIMS for undergraduate medical students in India. The study adopted different approaches and methods, but Delphi was the most critical method used in this research. In Delphi, the experts were contacted by e-mail and their feedback on the same was analyzed. Two rounds of Delphi were conducted in which 150 participants were contacted in Delphi-I but only 46 responded. In Delphi-II, 26 participants responded whose responses were finally considered for analysis. Three of the core competencies namely clinician, primary-care physician, and professionalism were agreed by all the participants, and the least agreement was observed in the competencies of epidemiologist and medical teacher. The experts having more experience were less consistent as responses were changed from agree to disagree in more than 15% of participants and 6% changed from disagree to agree. Within the given constraints, the final list of competencies and skills for the discipline of CMFM compiled after the Delphi process will provide a useful insight into the development of competency-based curriculum of the subject.

  6. Preliminary test of effects of cognitive ability, experience, and teaching methods on Verbal Analogy Test scores.

    Science.gov (United States)

    Rosenberg, D; Willson-Quayle, A; Pasnak, R

    2000-06-01

    The methods from which one can choose when preparing for the GRE Verbal Analogies include books, software, audiotapes, and formal classroom instruction. What teaching method will work best for a given individual? To begin the search for an answer, Gray's test of reasoning ability was given to 28 undergraduates who also answered a questionnaire detailing their experience with analogies. They were randomly assigned to teaching conditions ranging from self-directed workbook study to intensive interactive assistance. No teaching method was superior overall, but interactions showed that (1) students who scored worst on the pretest improved the most, (2) those higher in cognitive functioning and experience performed better after intensive interactive assistance, and (3) those lower in both cognitive functioning and experience did significantly better with self-paced workbooks. This preliminary work suggests that it may be profitable to assess the prior experience and reasoning of potential students and adopt the methods for teaching formal operational thought found empirically to be most suitable.

  7. Preliminary Results from the PrimEx-II experiment at Jefferson Lab

    Energy Technology Data Exchange (ETDEWEB)

    Gasparian, Ashot [NCA& T, Greensboro, NC; Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)

    2016-06-01

    Properties of the neutral pion, as the lightest hadron in Nature, are most sensitive to the basic symmetries and their partial breaking effects in the theory of the strong interaction (QCD). In particular, the po →gg decay width is primarily defined by the spontaneous chiral symmetry breaking effect (chiral anomaly) in QCD. The next order corrections to the anomaly have been shown to be small and are known to a 1% precision level. The PrimEx Collaboration at JLab has developed and performed two Primakoff type experiments to measure the po →gg decay width with a similar precision. The published result from the PrimEx-I experiment, G(p0 →gg ) = 7.82±0.14 (stat.)±0.17 (syst.) eV, was a factor of two more precise than the average value quoted in PDG-2010 [1]. The second experiment was performed in 2010 with a goal of 1.4% total uncertainty to address the next-to-leading-order theory calculations. The preliminary results from the PrimEx-II experiment are presented and discussed in this note.

  8. Establishment of a renal supportive care program: Experience from a rural community hospital in Taiwan.

    Science.gov (United States)

    Chao, Chia-Ter; Tsai, Hung-Bin; Shih, Chih-Yuan; Hsu, Su-Hsuan; Hung, Yu-Chien; Lai, Chun-Fu; Ueng, Ruey-Hsiuang; Chan, Ding-Cheng; Hwang, Juey-Jen; Huang, Sheng-Jean

    2016-07-01

    Renal supportive care (RSC) denotes a care program dedicated for patients with acute, chronic renal failure, and end-stage renal disease (ESRD), aiming to offer maximal symptom relief and optimize patients' quality of life. The uncertainty of prognosis for patients with chronic kidney disease and ESRD, the sociocultural issues inherent to the Taiwanese society, and the void of structured and practical RSC pathway, contributes to the underrecognition and poor utilization of RSC. Taiwanese patients rarely receive information regarding RSC as part of a standardized care and are not commonly offered this option. In National Taiwan University Hospital Jinshan branch, we started a RSC subprogram, supported by the community-based palliative/hospice care main program. We focused on understanding the need and providing the choice of RSC to suitable candidates. A three-step and four-phase protocol was designed and implemented to identify appropriate patients and to enhance the applicability of the RSC. We harnessed family visit and home-based family meeting as a vehicle to understand the patients' preferences, to discover what ESRD patients and their family value most, and to introduce the option of RSC. In the current review, we described our pilot experience of establishing a RSC program in Taiwan, and discuss its potential advantage.

  9. Establishment of a renal supportive care program: Experience from a rural community hospital in Taiwan

    Directory of Open Access Journals (Sweden)

    Chia-Ter Chao

    2016-07-01

    Full Text Available Renal supportive care (RSC denotes a care program dedicated for patients with acute, chronic renal failure, and end-stage renal disease (ESRD, aiming to offer maximal symptom relief and optimize patients' quality of life. The uncertainty of prognosis for patients with chronic kidney disease and ESRD, the sociocultural issues inherent to the Taiwanese society, and the void of structured and practical RSC pathway, contributes to the underrecognition and poor utilization of RSC. Taiwanese patients rarely receive information regarding RSC as part of a standardized care and are not commonly offered this option. In National Taiwan University Hospital Jinshan branch, we started a RSC subprogram, supported by the community-based palliative/hospice care main program. We focused on understanding the need and providing the choice of RSC to suitable candidates. A three-step and four-phase protocol was designed and implemented to identify appropriate patients and to enhance the applicability of the RSC. We harnessed family visit and home-based family meeting as a vehicle to understand the patients' preferences, to discover what ESRD patients and their family value most, and to introduce the option of RSC. In the current review, we described our pilot experience of establishing a RSC program in Taiwan, and discuss its potential advantage.

  10. NCloud - Experimenting with Architecting and Facilitating Utility Services for establishing Educational Cloud

    Directory of Open Access Journals (Sweden)

    Madhuri Bhavsar

    2013-06-01

    Full Text Available Academic Institutions as well as Enterprises all over the globe have become heavily dependent on high performance computing systems for their day to day activities and hence it continues to seek opportunities to rationalize and optimize the utilization of resources. Continuous upgradation  of software and hardware have become important items of those organizations meetings creating budget pressure. In such scenario, Cloud computing services could provide many of those organizations to enhance the productivity keeping the budget expenditure low.The paper discusses the experiments carried out on our educational campus for architecting the cloud – hereafter referred as NCloud (Cloud built on Nirma Campus, configured using open source tools, furnishes the utility services which is leading towards an establishment of  a stepping stone for formation of knowledge cloud. Testbed formed for data center consists of 1 front-end and 16 worker node.  By using NCloud, user will be able to fulfill the demand  of infrastructure as a service in which user is provided an operating system with specific RAM and CPU cores. Utility oriented services in NCloud aims to charge user for what they use. For implementing utility oriented services, analysis of various major cloud providers is done including pricing models. Performance measures on heterogeneous platforms and the results obtained are included in the paper.

  11. HACCP and water safety plans in Icelandic water supply: preliminary evaluation of experience.

    Science.gov (United States)

    Gunnarsdóttir, María J; Gissurarson, Loftur R

    2008-09-01

    Icelandic waterworks first began implementing hazard analysis and critical control points (HACCP) as a preventive approach for water safety management in 1997. Since then implementation has been ongoing and currently about 68% of the Icelandic population enjoy drinking water from waterworks with a water safety plan based on HACCP. Preliminary evaluation of the success of HACCP implementation was undertaken in association with some of the waterworks that had implemented HACCP. The evaluation revealed that compliance with drinking water quality standards improved considerably following the implementation of HACCP. In response to their findings, waterworks implemented a large number of corrective actions to improve water safety. The study revealed some limitations for some, but not all, waterworks in relation to inadequate external and internal auditing and a lack of oversight by health authorities. Future studies should entail a more comprehensive study of the experience with the use of HACCP with the purpose of developing tools to promote continuing success.

  12. Experiments, conceptual design, preliminary cost estimates and schedules for an underground research facility

    Energy Technology Data Exchange (ETDEWEB)

    Korbin, G.; Wollenberg, H.; Wilson, C.; Strisower, B.; Chan, T.; Wedge, D.

    1981-09-01

    Plans for an underground research facility are presented, incorporating techniques to assess the hydrological and thermomechanical response of a rock mass to the introduction and long-term isolation of radioactive waste, and to assess the effects of excavation on the hydrologic integrity of a repository and its subsequent backfill, plugging, and sealing. The project is designed to utilize existing mine or civil works for access to experimental areas and is estimated to last 8 years at a total cost for contruction and operation of $39.0 million (1981 dollars). Performing the same experiments in an existing underground research facility would reduce the duration to 7-1/2 years and cost $27.7 million as a lower-bound estimate. These preliminary plans and estimates should be revised after specific sites are identified which would accommodate the facility.

  13. Fetal magnetic resonance imaging: jumping from 1.5 to 3 tesla (preliminary experience)

    Energy Technology Data Exchange (ETDEWEB)

    Victoria, Teresa [The Children' s Hospital of Philadelphia, Radiology Department, Center for Fetal Diagnosis and Treatment, Philadelphia, PA (United States); Jaramillo, Diego; Roberts, Timothy Paul Leslie; Zarnow, Deborah; Johnson, Ann Michelle; Delgado, Jorge; Vossough, Arastoo [The Children' s Hospital of Philadelphia, Radiology Department, Philadelphia, PA (United States); Rubesova, Erika [Stanford University, Department of Radiology, Lucile Packard Children' s Hospital, Stanford, CA (United States)

    2014-04-15

    Several attempts have been made at imaging the fetus at 3 T as part of the continuous search for increased image signal and better anatomical delineation of the developing fetus. Until very recently, imaging of the fetus at 3 T has been disappointing, with numerous artifacts impeding image analysis. Better magnets and coils and improved technology now allow imaging of the fetus at greater magnetic strength, some hurdles in the shape of imaging artifacts notwithstanding. In this paper we present the preliminary experience of evaluating the developing fetus at 3 T and discuss several artifacts encountered and techniques to decrease them, as well as safety concerns associated with scanning the fetus at higher magnetic strength. (orig.)

  14. Post-depositional changes in snow isotope content: preliminary results of laboratory experiments

    Directory of Open Access Journals (Sweden)

    A. A. Ekaykin

    2009-10-01

    Full Text Available Isotopic content of the snow and firn thickness is assumed to be altered significantly due to the post-depositional (PD mass- and isotope exchange with the atmospheric water vapor. If so, these effects should be accounted for in the ice core-based isotope-temperature paleo-reconstructions. In order to study the intensity of the PD processes we set up a series of laboratory experiments. In this paper we describe in detail the experimental technique and briefly overview preliminary results. It is shown that the PD modifications in the upper layer of snow thickness are noticeably strong even under such a low temperature as −35°C (the value typical for the Central Antarctic summer. It is demonstrated that the PD isotopic changes in snow can be approximated as a linear function of the relative mass loss due to snow sublimation. Possible applications for improving the isotope-temperature paleo-reconstructions are shortly discussed.

  15. A PRELIMINARY STUDY ON THE ESTABLISHMENT OF OCEAN TIDE MODELS OVER THE SOUTH CHINA SEA FROM T/P ALTIMETRY

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    On the basis of the characteristic of the perfect spatial distribution of th e T/P altimeter data,a spatial harmonic tidal analysis is performed,which tran sfers tidal harmonic constants H and g of each constituent into a pair o f parame ters:the cosine part U and sine part V.And each part is expanded into a po lynomi al.The polynomial coefficients are estimated with altimeter data upon the least squares criteria.Thus the models of principal tidal waves in the South China S ea are established.72 cycles of T/P data from cycle 11 through 82 ar e included in the calculation.The models are evaluated with different approache s and data set.The conclusions are that the tide modes can provide partial tide amplitudes with 3 cm accuracy,and that phase lags deviation of those tides w ith amplitude large than 10 cm are within ±10°.

  16. Screening diagnostics of antivital experiences and propensity toward impulsive, autoagressive behavior in adolescents (preliminary results

    Directory of Open Access Journals (Sweden)

    Bannikov G.S.,

    2014-08-01

    Full Text Available Development of methods for revealing antivital experiences and propensity to autoaggressive behavior in educational institutions is one of the key steps in developing strategies for the primary prevention of suicidal behavior in adolescents. The purpose of this study was to develop an effective screening diagnostic package aimed at identifying antivital experiences and propensity to autoaggressive behavior. The survey methods we used were: Beck Hopelessness Scale, Russell Loneliness Scale, A.G. Shmelev Suicide Risk Questionnaire, PDQ-IV Borderline disorder and Narcissism scales. At the first stage we examined 750 minors aged 12-18 and identified risk group (85 people – 11.4%, which included adolescents with high levels of both individual scales, and their combination. At the second stage we examined 10 adolescents at risk. In 7 of them (70% were identified antivital, suicidal thoughts of passive or compulsive nature, signs of subjective and objective socio- psychological maladjustment. Our preliminary conclusion is that high levels of hopelessness and loneliness in adolescents are stable predictors of mental and emotional distress and psychosocial maladjustment in the period of psychological crises and decompensation of character accentuation of borderline and narcissistic types. These scales can be recommended for primary screening of antivital (depressive experiences and propensity to autoaggressive behavior in adolescents.

  17. Beneficial uses of geothermal energy description and preliminary results for phase 1 of the Raft River irrigation experiment

    Energy Technology Data Exchange (ETDEWEB)

    Schmitt, R.C.; Spencer, S.G.

    1977-01-01

    The first phase of an experiment using geothermal water for irrigation is described and preliminary results are discussed. The water was from a moderate temperature well, having salinity of about 2000 ppM, and is considered characteristic of the types of geothermal fluids that will be obtained from the young volcanic/young sediment formations of the northern intermountain west. The activity was completed at a location adjacent to ERDA's Raft River Geothermal Project in southern Idaho. About 12.5 acres, of which part had no previous cultivation, were subdivided by crops and irrigation practices for investigation with the geothermal water and a control comparison water from the relatively pure Raft River. Flood and sprinkler application techniques were used and wheat, barley, oats, grasses, alfalfa, potatoes, and garden vegetables were successfully grown. An accompanying experiment evaluated the behavior of an established alfalfa crop located nearby, when most of the irrigation water was geothermal. The experiment addressed heavy metal uptake in plants, plant fluoride retention and damage, plant tolerances to salts, soil alterations and other behavior as a result of the geothermal fluids, all of which were largely believed to eliminate geothermal water from contention for crop growing utilization. Not all analyses and results are complete in this reporting, but first results indicate no apparent difference between the geothermal watered crops and those obtained using the fresh water control. Extensive chemical analyses, neutron activation analyses, and other evaluations of crop samples are discussed, and some of the findings are presented. Although evaluation of crop yields was not an objective, extrapolations from samples indicate that yield results were comparable to those commonly found in the area, and the yield varied little between water sources. (JGB)

  18. Preliminary experience with dexmedetomidine for monitored anesthesia care during ENT surgical procedures.

    Science.gov (United States)

    Busick, Tamra; Kussman, Mary; Scheidt, Troy; Tobias, Joseph D

    2008-01-01

    Dexmedetomidine is an alpha2-adrenergic agonist that produces anxiolysis, amnesia, sedation, potentiation of opioid analgesia, and sympatholysis. It is currently approved by the U.S. Food & Drug Administration for the sedation of adults in the intensive care setting for up to 24 hours during mechanical ventilation. Given its beneficial sedative and anxiolytic properties and limited adverse effect profile, it has been used in several other clinical scenarios. The authors present their experience using dexmedetomidine for monitored anesthesia care (MAC) during "awake" ENT procedures such as thyroplasty, a procedure requiring a patient to verbalize when requested but to otherwise remain immobile to allow for completion of the procedure, and in a patient with post-polio syndrome with poor pulmonary reserve requiring esophagoscopy with dilation and botulinum toxin injection for cricopharyngeal dysfunction. Our preliminary experience suggests that dexmedetomidine provides effective sedation as the primary agent for MAC during such procedures in adult patients. The end-organ effects of dexmedetomidine and previous reports of its use during MAC are reviewed.

  19. Preliminary experiments on pharmacokinetic diffuse fluorescence tomography of CT-scanning mode

    Science.gov (United States)

    Zhang, Yanqi; Wang, Xin; Yin, Guoyan; Li, Jiao; Zhou, Zhongxing; Zhao, Huijuan; Gao, Feng; Zhang, Limin

    2016-10-01

    In vivo tomographic imaging of the fluorescence pharmacokinetic parameters in tissues can provide additional specific and quantitative physiological and pathological information to that of fluorescence concentration. This modality normally requires a highly-sensitive diffuse fluorescence tomography (DFT) working in dynamic way to finally extract the pharmacokinetic parameters from the measured pharmacokinetics-associated temporally-varying boundary intensity. This paper is devoted to preliminary experimental validation of our proposed direct reconstruction scheme of instantaneous sampling based pharmacokinetic-DFT: A highly-sensitive DFT system of CT-scanning mode working with parallel four photomultiplier-tube photon-counting channels is developed to generate an instantaneous sampling dataset; A direct reconstruction scheme then extracts images of the pharmacokinetic parameters using the adaptive-EKF strategy. We design a dynamic phantom that can simulate the agent metabolism in living tissue. The results of the dynamic phantom experiments verify the validity of the experiment system and reconstruction algorithms, and demonstrate that system provides good resolution, high sensitivity and quantitativeness at different pump speed.

  20. Augmented Reality Cubes for Cognitive Gaming: Preliminary Usability and Game Experience Testing

    Directory of Open Access Journals (Sweden)

    Costas Boletsis

    2016-03-01

    Full Text Available Early detection is important in dementia care; however, cognitive impairment is still under-recognised and under-diagnosed. Cognitive screening and training are two important preventative treatments, which can lead to early detection of cognitive decline. In this work, the “Cognitive Augmented Reality Cubes” (CogARC system is presented, i.e. a serious game for cognitive training and screening, utilising an interaction technique based on Augmented Reality and the manipulation of tangible, physical objects (cubes. The game is a collection of cognitive mini-games of preventative nature and is, primarily, targeting elderly players (≥60 years old. A preliminary testing was conducted focusing on the game experience that CogARC offers (utilising the In-Game Experience Questionnaire, the usability of the system (using the System Usability Scale, and the specific user observations and remarks, as documented by open, semi-structured interviews.  Overall, CogARC demonstrated satisfying positive responses, however, the negative reactions indicated that there are specific problems with aspects of the interaction technique and a number of mini-games. The open interview shed more light on the specific issues of each mini-game and further interpretation of user interactions. The current study managed to provide interesting insights into the game design elements, integration of Augmented Reality, tangible interaction of the system, and on how elderly players perceive and use those interaction components. 

  1. Preliminary experience with the MicroMed DeBakey pediatric ventricular assist device.

    Science.gov (United States)

    Fraser, Charles D; Carberry, Kathleen E; Owens, W Richard; Arrington, Karol A; Morales, David L S; Heinle, Jeffery S; McKenzie, E Dean

    2006-01-01

    Mechanical circulatory support for both acute and chronic heart failure is a widely applied therapeutic option in the adult population with a variety of devices clinically available. Technology in this field has advanced sufficiently such that long-term support or "destination therapy" has become a generally accepted reality. Similar progress has not occurred in the field of device support for heart failure in children. While the number of potential patients is significantly lower in the pediatric population, the clinical relevance and poignancy of individual need are nonetheless real. Until recently, children with heart failure have been largely disadvantaged in comparison to their adult counterparts. The DeBakey VAD Child (MicroMed Technology, Inc, Houston, TX) represents a hopeful initial step in the direction of reducing the technological gap between adults and children. While the clinical experience with this device is limited at present, preliminary results are encouraging. This report will provide an overview of the DeBakey VAD Child, including device specifications, indications for clinical use, surgical and postoperative considerations, and updated clinical experience.

  2. Preliminary Flight Results of the Microelectronics and Photonics Test Bed: NASA DR1773 Fiber Optic Data Bus Experiment

    Science.gov (United States)

    Jackson, George L.; LaBel, Kenneth A.; Marshall, Cheryl; Barth, Janet; Seidleck, Christina; Marshall, Paul

    1998-01-01

    NASA Goddard Spare Flight Center's (GSFC) Dual Rate 1773 (DR1773) Experiment on the Microelectronic and Photonic Test Bed (MPTB) has provided valuable information on the performance of the AS 1773 fiber optic data bus in the space radiation environment. Correlation of preliminary experiment data to ground based radiation test results show the AS 1773 bus is employable in future spacecraft applications requiring radiation tolerant communication links.

  3. THE EXPERIENCE OF FORMATION OF ESTABLISHMENTS OF OUT - SCHOOL EDUCATION IN UKRAINE

    Directory of Open Access Journals (Sweden)

    KOVALSKA G. L.

    2015-10-01

    Full Text Available Problem statement. Modern socio-economic conditions set new educational challenges in Ukraine influencing on the town planning aspects of development the network of different types of educational establishments, their location in building, architectural solutions. Ukrainian national model of out-school education is unique and reflects social and national specification of pedagogical development. All integrated innovations should be thoroughly comprehended and analyzed. During the years of development an extensive network of out-school education in the cities of Ukraine has been developed. There is a marked shortage of out-school educational establishments. Youth palaces of old type are not working at present. School clubs are not numerous and depressive with tendency to be totally eliminated. Unfortunately, existing normative base is still insufficient for complete extracurricular establishment network creation. Article’s purpose. To analyze problems, concerning out-school educational network formation and to provide suggestions regarding the calculation of the area of land plot. Conclusions. A number of issues stipulated by lack of appropriate scientific and conceptual works and regulatory parameters while improving of the network of out-school educational establishments arises. The problem areas in the regulatory framework are pointed out and possible solution has been proposed. The earlier a work program, authorized by the general out-school educational development will be formulated, the sooner the network of out-school establishments and improvement of quality of architectural and town planning solutions will be appeared.

  4. Supporting Students in the Margins: Establishing a First-Year Experience for LGBTQA Students

    Science.gov (United States)

    Squire, Dian; Norris, Lauren

    2014-01-01

    This paper describes the creation of a comprehensive First-Year Experience program for lesbian, gay, bisexual, transgender, queer, and ally (LGBTQA) students. Background information on First-Year Experience programs, LGBTQA populations, and the benefits of providing this program are described. The authors discuss how to plan and implement this…

  5. Prospectively gated axial CT coronary angiography: preliminary experiences with a novel low-dose technique

    Energy Technology Data Exchange (ETDEWEB)

    Klass, Oliver; Jeltsch, Martin; Feuerlein, Sebastian; Brunner, Horst; Brambs, Hans-Juergen; Hoffmann, Martin H.K. [University Hospital of Ulm, Department of Diagnostic and Interventional Radiology, Ulm (Germany); Nagel, Hans-Dieter [Philips Healthcare, Department of Science and Technology, Hamburg (Germany); Walker, Matthew J. [CT Clinical Science, Philips Healthcare, Cleveland, OH (United States)

    2009-04-15

    To assess image quality and radiation exposure with prospectively gated axial CT coronary angiography (PGA) compared to retrospectively gated helical techniques (RGH). Forty patients with suspected coronary artery disease (CAD) and a stable heart rate below 65 bpm underwent CT coronary angiography (CTCA) using a 64-channel CT system. The patient cohort consisted of 20 consecutive patients examined using a PGA technique and 20 patients examined using a standard RGH technique. Both groups were matched demographically according to age, gender, body mass index, and heart rate. For both groups, two independent observers assessed image quality for all coronary segments on an ordinal scale from 1 (nonassessable) to 5 (excellent quality). Image quality and radiation exposure were compared between patient groups. There were no significant differences in vessel-based image quality between the two groups (P > 0.05). Mean ({+-} SD) effective radiation exposure in the PGA group was 3.7 {+-} 0.8 mSv compared to 18.9 {+-} 3.8 mSv in the RGH group without ECG-based tube current modulation (P < 0.001). Preliminary experience shows PGA technique to be a promising approach for CTCA resulting in a substantial reduction in radiation exposure with image quality comparable to that of standard RGH technique. (orig.)

  6. Preliminary experience with drug-coated balloon angioplasty in primary percutaneous coronary intervention

    Institute of Scientific and Technical Information of China (English)

    Hee; Hwa; Ho; Julian; Tan; Yau; Wei; Ooi; Kwok; Kong; Loh; Than; Htike; Aung; Nwe; Tun; Yin; Dasdo; Antonius; Sinaga; Fahim; Haider; Jafary; Paul; Jau; Lueng; Ong

    2015-01-01

    We evaluated the clinical feasibility of using drugcoated balloon(DCB) angioplasty in patients undergoingprimary percutaneous coronary intervention(PPCI). Between January 2010 to September 2014,89 STelevation myocardial infarction patients(83% male,mean age 59 ± 14 years) with a total of 89 coronary lesions were treated with DCB during PPCI. Clinical outcomes are reported at 30 d follow-up. Left anterior descending artery was the most common target vessel for PCI(37%). Twenty-eight percent of the patients had underlying diabetes mellitus. Mean left ventricular ejection fraction was 44% ± 11%. DCB-only PCI was the predominant approach(96%) with the remaining 4% of patients receiving bail-out stenting. Thrombolysis in Myocardial Infarction(TIMI) 3 flow was successfully restored in 98% of patients. An average of 1.2 ± 0.5 DCB were used per patient,with mean DCB diameter of 2.6 ± 0.5 mm and average length of 23.2 ± 10.2 mm. At 30-d follow-up,there were 4 deaths(4.5%). No patients experienced abrupt closure of the infarctrelated artery and there was no reported target-lesion failure. Our preliminary experience showed that DCB angioplasty in PPCI was feasible and associated with a high rate of TIMI 3 flow and low 30-d ischaemic event.

  7. Pool film boiling experiments on a wire in low gravity: preliminary results.

    Science.gov (United States)

    Di Marco, P; Grassi, W; Trentavizi, F

    2002-10-01

    This paper reports preliminary results for pool film boiling on a wire immersed in almost saturated FC72 recently obtained during an experimental campaign performed in low gravity on the European Space Agency Zero-G airplane, (reduced gravity level 10(-2)). This is part of a long-term research program on the effect of gravitational and electric forces on boiling. The reported data set refers to experiments performed under the following conditions: (1) Earth gravity without electric field, (2) Earth gravity with electric field, (3) low gravity without electric field, and (4) low gravity with electric field. Although a decrease of gravity causes a heat transfer degradation, the electric field markedly improves heat exchange. This improvement is so effective that, beyond a certain field value, the heat flux is no longer sensitive to gravity. Two main film boiling regimes have been identified, both in normal and in low gravity: one is affected by the electric field and the other is practically insensitive to the field influence.

  8. Electromagnetic experiment to map in situ water in heated welded tuff: Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Ramirez, A.L.; Daily, W.D.

    1987-03-16

    An experiment was conducted in Tunnel Complex G at the Nevada Test Site to evaluate geotomography as a possible candidate for in situ monitoring of hydrology in the near field of a heater placed in densely welded tuff. Alterant tomographs of 200 MHz electromagnetic permittivity were made for a vertical and a horizontal plane. After the 1 kilowatt heater was turned on, the tomographs indicated a rapid and strong drying adjacent to the heater. Moisture loss was not symmetric about the heater, but seemed to be strongly influenced by heterogeneity in the rock mass. The linear character of many tomographic features and their spatial correlation with fractures mapped in boreholes are evidence that drying was most rapid along some fractures. When the heater was turned off, an increase in moisture content occurred around the heater and along the dry fractures. However, this process is much slower and the magnitude of the moisture increase much smaller than the changes observed during heating of the rock. The interpretation of the tomographs is preliminary until they can be processed without the restrictive assumption of straight ray paths for the signals through the highly heterogeneous rock mass. 15 refs., 4 figs.

  9. Preliminary experience with laparoscopic repair of associated inguinal and umbilical hernias in children.

    Science.gov (United States)

    Bertozzi, M; Magrini, E; Appignani, A

    2015-08-01

    The authors report their preliminary experience in laparoscopic repair of associated inguinal and umbilical hernias in children. Twenty-six patients affected by the association of inguinal and umbilical hernia with an umbilical defect larger than 5 mm underwent a laparoscopic procedure. A 5-mm trocar was placed through the umbilical defect for the optic. To fix the trocar to avoid loss of carboperitoneum, we fashioned and tightened a purse-string non-absorbable suture with a sliding knot around the defect. In this manner, we ensured the trocar, fixing it and avoiding any loss of CO2, proceeding safely to the laparoscopic IH repair, by means of two additional 3 mm operative trocars. At the end of the inguinal herniorrhaphy, the previously fashioned purse-string suture was tightened to repair the umbilical defect. The mean operative time for the repair of associated inguinal and umbilical hernias was 30.1 ± 7.4 min in cases of unilateral inguinal hernia and 39.5 ± 10.6 for bilateral inguinal hernia. Follow-up ranged from 8 to 32 months. Neither intra- nor post-operative complications nor recurrences were seen. This small sample suggests that this simple method is safe, effective and might be useful for pediatric surgeons performing laparoscopic repair for inguinal hernia in presence of an associated UH with a statistically significant decrease of operative time.

  10. Preliminary Λ ^0 arrow p + π ^- Signal for SELEX - Fermilab Experiment 781

    Science.gov (United States)

    Parkhurst, James F.; Dauwe, Loretta J.; E781 Collaboration

    1997-10-01

    SELEX (SEgmented Large X baryon spectrometer), a fixed target experiment at Fermilab, collected data from February to September 1997, using both 650 GeV/c Σ ^-/π ^-, and 550 GeV/c p/π ^+ beams. This run resulted in 2 billion triggered interactions being logged to tape. Primarily designed to study charmed baryons, E781 can also study hyperon production and decays, and the Primakoff effect. Λ ^0 has several decay modes, however it primarily decays into a p and π ^-. A neutral particle decay to two charged particles appears in the spectrometer as two oppositely charged tracks, originating downstream from the primary interaction in the target. Spectrometer magnets provide a transverse momentum kick which spreads the particle trajectories in a direction depending on the particles' charge. Particle momentum is determined from knowledge of the magnetic field and the track curvature. Assuming masses for the positive and negative tracks, the invariant mass and momentum of the initial neutral particle is calculated. A preliminary reconstruction of Λ ^0 decay, including the mass distribution, will be presented.

  11. [The lived experience of family member caring for a person affected by Alzheimer's disease: preliminary results].

    Science.gov (United States)

    Vellone, E; Micci, F; Sansoni, J; Sinapi, N; Cattel, C

    2000-01-01

    The aim of this article is to report the preliminary results from a phenomenological study on the lived experience of Alzheimer's caregivers. Eight caregivers involved in caring for two years at list were interviewed. The analysis of interviews by Giorgi's method showed a multidimensional reality synthesizable in eight spheres of themes: Illness, Patient, Caring, Caregiver's Life and Health, Coping, Spouse/Family, Others, Feelings. Illness has a great impact on the caregivers' life and causes the loss of the affected person even before his/her death. Caring is very hard and emotionally involving. Caregivers mainly complain the lack of support from the National Health System. The continuous involvement in caring produces also health problems, depression, and negative effects within the family. Others are considered as bad. The most common feelings are fear for possible accidents to the patients and remorses. Some caregivers have good coping style putting their faith in God, valuing the closeness of the family and living daily. The utility of the eight spheres of themes are discussed in order to guide the practice toward the caregivers.

  12. Universal newborn hearing screening: preliminary experience at the University Hospital of Cagliari

    Directory of Open Access Journals (Sweden)

    Giulia Pinna

    2012-10-01

    Full Text Available Bilateral congenital or acquired sensorineural hearing loss is a pathological condition affecting 1-2 children per 1,000 live births; it represents a major issue in public health because its late identification can negatively affect speech and language development. The aim of hearing screening is to obtain diagnosis and management of hearing loss as soon as possible; in fact early diagnosis and treatment allow children with congenital hearing impairment to acquire adequate linguistic competence. The present study reports our preliminary experience in newborn hearing screening at Neonatology services of University of Cagliari (Italy. During the first semester of surveillance, between January 2012 and June 2012, hearing screening was performed on a total of 901 babies using two different methods, TEOAEs in healthy neonates and automated ABR in high-risk babies. All infants were screened prior to hospital discharge; in some cases, especially for preterm infants of Neonatal Intensive Care Unit and Puericulture Institute, the screening was performed after discharge, to achieve a possible better global and acoustic maturation; 5 cases of hearing impairment were found. In the present study the Authors confirmed that it is possible to start a universal hearing screening in a relatively short time reaching the percentages suggested by Joint Committee on Infant Hearing.

  13. Wageningen Urban Rainfall Experiment 2014 (WURex14): Experimental setup and preliminary results

    Science.gov (United States)

    van Leth, Thomas C.; Uijlenhoet, Remko; Overeem, Aart; Leijnse, Hidde; Hazenberg, Pieter; Berne, Alexis

    2016-04-01

    Microwave links from cellular communication networks have been shown to be able to provide valuable information concerning the space-time variability of rainfall. In particular over urban areas, where network densities are generally high, they have the potential to complement existing dedicated infrastructure to measure rainfall (gauges, radars). In addition, microwave links provide a great opportunity for ground-based rainfall measurement for those land surface areas of the world where gauges and radars are generally lacking. Such information is not only crucial for water management and agriculture, but also for instance for ground validation of space-borne rainfall estimates such as those provided by the GPM (Global Precipitation Measurement) mission. WURex14 is dedicated to address several errors and uncertainties associated with such quantitative precipitation estimates in detail. The core of the experiment is provided by three co-located microwave links installed between two major buildings on the Wageningen University campus, approximately 2 km apart: a 38 GHz commercial microwave link, provided by T-Mobile NL, and 26 GHz and 38 GHz (dual-polarization) research microwave links from RAL. Transmitting and receiving antennas have been attached to masts installed on the roofs of the two buildings, about 30 m above the ground. This setup has been complemented with a Scintec infrared Large-Aperture Scintillometer, installed over the same path, as well as 5 Parsivel optical disdrometers and an automated rain gauge positioned at several locations along the path. Temporal sampling of the received signals was performed at a rate of 20 Hz. The setup is being monitored by time-lapse cameras to assess the state of the antennas as well as the atmosphere. Finally, data is available from the KNMI weather radars and an automated weather station situated just outside Wageningen. The experiment has been active between August 2014 and December 2015. We give a global overview of

  14. Compressed air energy storage: Preliminary design and site development program in an aquifer. Task 1: Establish facility design criteria and utility benefits

    Science.gov (United States)

    1980-10-01

    Compressed air energy storage (CAES) stores mechanical energy in the form of compressed air during off-peak hours, using power supplied by a large, high efficiency baseload power plant. At times of high electrical demand, the compressed air is drawn from storage and is heated in a combustor by the burning of fuel oil, after which the air is expanded in a turbine. Essentially all of the turbine output can be applied to the generation of electricity, unlike a conventional gas turbine which expends approximately two-thirds of the turbine shaft power in driving the air compressor. The separation of the compression and generation modes in the system results in increased net generation and greater premium fuel economy. Work performed in establishing facility design criteria for a CAES system with aquifer storage includes: determination of initial design bases; preliminary analysis of the CAES system; development of data for site-specific analysis of the CAES system; detailed analysis of the CAES system for three selected heat cycles; CAES power plant design; and an economic analysis of CAES.

  15. Compressed air energy storage: preliminary design and site development program in an aquifer. Final draft, Task 1: establish facility design criteria and utility benefits

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-10-01

    Compressed air energy storage (CAES) has been identified as one of the principal new energy storage technologies worthy of further research and development. The CAES system stores mechanical energy in the form of compressed air during off-peak hours, using power supplied by a large, high-efficiency baseload power plant. At times of high electrical demand, the compressed air is drawn from storage and is heated in a combustor by the burning of fuel oil, after which the air is expanded in a turbine. In this manner, essentially all of the turbine output can be applied to the generation of electricity, unlike a conventional gas turbine which expends approximately two-thirds of the turbine shaft power in driving the air compressor. The separation of the compression and generation modes in the CAES system results in increased net generation and greater premium fuel economy. The use of CAES systems to meet the utilities' high electrical demand requirements is particularly attractive in view of the reduced availability of premium fuels such as oil and natural gas. This volume documents the Task 1 work performed in establishing facility design criteria for a CAES system with aquifer storage. Information is included on: determination of initial design bases; preliminary analysis of the CAES system; development of data for site-specific analysis of the CAES system; detailed analysis of the CAES system for three selected heat cycles; CAES power plant design; and an economic analysis of CAES.

  16. Preliminary study of the effects of preventive measures on the prevalence of Canine Leishmaniosis in a recently established focus in northern Italy

    Directory of Open Access Journals (Sweden)

    Rudi Cassini

    2013-06-01

    Full Text Available Canine Leishmaniosis is endemic in Mediterranean areas, with a well-documented northward spread. The mass use of preventive measures against sandfly bites (collar and spot-on formulations was tested in a small focus recently established in an isolated hilly area of north-eastern Italy (Colli Euganei. In 2006 and 2007, a total of 449 dogs living in the southern part of Colli Euganei were screened against Leishmania infantum using an immunofluorescence antibody test (IFAT, and 31 (6.9% were seropositive. A risk factor analysis clearly described the focus as limited to a small village named Calaone. In 2010, 63 animals from Calaone were sampled and their owners interviewed to verify the effectiveness of the preventive measures. According to what reported by owners, dogs started to be protected in 2006 (66.7% dogs protected, and protection rate incremented (around 90% during the subsequent years. The seroprevalence value (4.2% of the youngest age class (<5 years was significantly lower than other classes, demonstrating that animals born after 2006 had low probabilities of getting infected. Besides, seroprevalence value referred only to dogs living in Calaone was 32.4% (23/71 in 2006-2007 and 20.6% (13/63 in 2010, showing a decreasing trend. Although still preliminary, the results show high sensitization of dog owners and suggest that the mass use of collars and spot-on acts positively in reducing the circulation of L. infantum.

  17. Norwegian fjords as potential sites for CO{sub 2} experiments. A preliminary feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    Golmen, Lars G.; Soerensen, Jan; Haugan, Peter; Bakke, Torgeir; Bjerknes, Vilhelm

    1997-12-31

    Large-scale deposition of CO{sub 2} will probably take place deep in the open oceans. But small-scale experiments on plume dynamics and chemical or biological impacts are more conveniently performed in Norwegian fjords. This report describes a feasibility study treating the physical, biological and legal constraints upon such experiments. Several small and large fjord basins with depths exceeding 500 m exist in western Norway. The report gives guidelines to what further steps should be taken to establish an in-situ CO{sub 2} experiment in a fjord. Twenty-six different basins have been identified in terms of maximum depths, municipal adherence etc. Deep water hydrographic conditions vary relatively little from one fjord to another. Data on the dynamical states and on deep water biology are in general lacking and a baseline study on selected fjords should be performed prior to the final selection. User conflicts and legal aspects must be considered and a complete EIA study will probably be required before any CO{sub 2} experiment can be started in a fjord. 60 refs., 13 figs.

  18. Preliminary stress characterization for an in-situ stimulation experiment at the Grimsel Underground Laboratory

    Science.gov (United States)

    Krietsch, Hannes; Doetsch, Joseph; Gischig, Valentin; Amann, Florian; Jalali, Mohammadreza; Madonna, Claudio; Evans, Keith; Valley, Benoit; Giardini, Domenico; Wiemer, Stefan; Maurer, Hansruedi; Loew, Simon

    2016-04-01

    A decameter-scale in-situ stimulation experiment is currently being executed at the Grimsel Test Site in Switzerland, spanning from hydraulic fracturing to controlled fault-slip experiments. For the feasibility of this project the in-situ stress tensor is of foremost importance. Therefore a unique stress characterization campaign combining stress relief methods (overcoring of USBM and CSIRO-HI probes) with hydraulic fracturing (HF) and hydraulic testing on pre-existing fractures (HTPF) in three boreholes was conducted in a first phase of this project. During all hydraulic stress measurements, micro-seismicity was monitored and localized in real time utilizing a dense network of piezo-electric sensors. In this contribution, we present preliminary results of the stress characterization and compare the derived stress tensor with previous estimates of the stress state. The stress characterization campaign was conducted in three boreholes, one sub-vertical and two sub-horizontal boreholes, assuming that the sub-vertical and one sub-horizontal are parallel to a principal stress component. A major task in this contribution is the integration of the different stress characterization methods. Our results of the different methods (overcoring and HF) are largely consistent, but disagree with some of the previous stress orientation estimates. From the new campaign the overcoring measurements indicate a sub-horizontal sigma1 of 17.3 MPa with a strike of 145°, a sigma2 of 9.7 MPa with 241°/69° and a sigma3 of 8.3 MPa with 055°/21° using an isotropic approach for inversion calculation. Whereas the USBM-Probe measures a projection of the principal stresses in a plane normal to borehole axis, the CSIRO-HI Probe provides the real 3D stress tensor. The HF and HTPF measurements indicate a far-field minimum horizontal stress between 8.7 and 9.1 MPa, consistent with the overcoring. Principal stresses, estimated by location of micro-seismic events during HF and HTPF, suggest that

  19. Establishment of an animal model of a pasteurized bone graft, with a preliminary analysis of muscle coverage or FGF-2 administration to the graft

    Directory of Open Access Journals (Sweden)

    Nakayama Koichi

    2009-08-01

    Full Text Available Abstract Background Pasteurized bone grafting is used following the excision of a bone tumor for the purpose of eliminating neoplastic cells while preserving bone-inducing ability. In the hopes of guaranteeing the most favourable results, the establishment of an animal model has been urgently awaited. In the course of establishing such a model, we made a preliminary examination of the effect of muscle coverage or fibroblast growth factor 2 (FGF-2 administration radiographically. Methods Forty pasteurized intercalary bone grafts of the Wistar rat femur treated at 60°C for 30 min were reimplanted and stabilized with an intramedullary nail (1.1 mm in diameter. Some grafts were not covered by muscle after the implantation, so that they could act as a clinical model for wide resection, and/or these were soaked with FGF-2 solution prior to implantation. The grafts were then divided into 3 groups, comprising 12 grafts with muscle-covering but without FGF-2 (MC+; FGF2-, 12 grafts without muscle-covering and without FGF-2 (MC-; FGF2- and 16 grafts without muscle covering but with FGF-2 (MC-; FGF2+. Results At 2 weeks after grafting, the pasteurized bone model seemed to be successful in terms of eliminating living cells, including osteocytes. At 4 weeks after grafting, partial bone incorporation was observed in half the (MC+; FGF2- cases and in half the (MC-; FGF2+ cases, but not in any of the (MC-; FGF2- cases. At 12 weeks after grafting, bone incorporation was seen in 3 out of 4 in the (MC+; FGF2- group (3/4: 75% and in 3 out of 8 in the (MC-; FGF2+ group (3/8: 38%. However, most of the grafted bones without FGF-2 were absorbed in all the cases, massively, regardless of whether there had been muscle-covering (MC+; FGF2-; 4/4: 100% or no muscle-covering (MC-; FGF2-; 4/4: 100%, while bone absorption was noted at a lower frequency (2/8: 25% and to a lower degree in the (MC-; FGF2+ group. Conclusion In conclusion, we have established an animal pasteurized

  20. Establishing and managing a periodontal biobank for research: the sharing of experience.

    Science.gov (United States)

    Vaithilingam, R D; Safii, S H; Baharuddin, N A; Karen-Ng, L P; Saub, R; Ariffin, F; Ramli, H; Sharifuddin, A; Hidayat, M F H; Raman, R; Chan, Y K; Rani, N A; Rahim, R A; Shahruddin, N; Cheong, S C; Bartold, P M; Zain, R B

    2015-01-01

    Periodontal bio-repositories, which allow banking of clinically validated human data and biological samples, provide an opportunity to derive biomarkers for periodontal diagnosis, prognosis and therapeutic activities which are expected to improve patient management. This article presents the establishing of the Malaysian Periodontal Database and Biobank System (MPDBS) which was initiated in 2011 with the aim to facilitate periodontal research. Partnerships were established with collaborating centres. Policies on specimen access, authorship and acknowledgement policies were agreed upon by all participating centres before the initiation of the periodontal biobank. Ethical approval for the collection of samples and data were obtained from institutional ethics review boards. A broad-based approach for informed consent was used, which covered areas related to quality of life impacts, genetics and molecular aspects of periodontal disease. Sample collection and processing was performed using a standardized protocol. Biobanking resources such as equipment and freezers were shared with the Malaysian Oral Cancer Database and Tissue Bank System (MOCDTBS). In the development of the MPDBS, challenges that were previously faced by the MOCDTBS were considered. Future challenges in terms of ethical and legal issues will be faced when international collaborations necessitate the transportation of specimens across borders.

  1. Student reflections following exposure to a case-based interprofessional learning experience: Preliminary findings.

    Science.gov (United States)

    Goldberg, Lynette R; Brown, Gina R; Mosack, Victoria A; Fletcher, Phyllis A

    2015-01-01

    This study analyzed students' written reflections following their initial exposure to interprofessional teamwork in case-based problem-solving. A three-hour seminar featuring three sequenced scenarios was developed and offered 12-times over two semesters. A total of 305 students from a variety of healthcare programs worked together with standardized patients in an on-campus laboratory simulating hospital ward and rehabilitation settings. A thematic analysis of students' reflections showed that they valued the shared learning and realistic case study. However, they felt the experience would be strengthened by working in smaller, more representative teams that included students from medicine, psychology, and social work to enable more effective communication and comprehensive case discussion. While useful for future planning, the identified themes did not enable a comparative statistical analysis of what students found helpful and difficult and a re-coding of students' responses now is underway. Implications for measuring the effectiveness of future interprofessional case-based learning center on addressing the identified weaknesses, and establishing a research design that enables a comparison of pre- and post-seminar data, and the effectiveness of the IPE experience compared to profession-specific experiences.

  2. Preliminary Results of the NASA Beacon Receiver for Alphasat Aldo Paraboni TDP5 Propagation Experiment

    Science.gov (United States)

    Nessel, James; Morse, Jacquelynne; Zemba, Michael; Riva, Carlo; Luini, Lorenzo

    2014-01-01

    NASA Glenn Research Center (GRC) and the Politecnico di Milano (POLIMI) have initiated a joint propagation campaign within the framework of the Alphasat propagation experiment to characterize rain attenuation, scintillation, and gaseous absorption effects of the atmosphere in the 40 GHz band. NASA GRC has developed and installed a K/Q-band (20/40 GHz) beacon receiver at the POLIMI campus in Milan, Italy, which receives the 20/40 GHz signals broadcast from the Alphasat Aldo Paraboni TDP#5 beacon payload. The primary goal of these measurements is to develop a physical model to improve predictions of communications systems performance within the Q-band. Herein, we describe the design and preliminary performance of the NASA propagation terminal, which has been installed and operating in Milan since May 2014. The receiver is based upon a validated Fast Fourier Transform (FFT) I/Q digital design approach utilized in other operational NASA propagation terminals, but has been modified to employ power measurement via a frequency estimation technique and to coherently track and measure the amplitude of the 20/40 GHz beacon signals. The system consists of a 1.2-m K-band and a 0.6-m Qband Cassegrain reflector employing synchronous open-loop tracking to track the inclined orbit of the Alphasat satellite. An 8 Hz sampling rate is implemented to characterize scintillation effects, with a 1-Hz measurement bandwidth dynamic range of 45 dB. A weather station with an optical disdrometer is also installed to characterize rain drop size distribution for correlation with physical based models.

  3. Risk of surgical site infection in paediatric herniotomies without any prophylactic antibiotics: A preliminary experience

    Directory of Open Access Journals (Sweden)

    Dhananjay Vaze

    2014-01-01

    Full Text Available Background: Different studies underline the use of pre-operative antibiotic prophylaxis in clean surgeries like herniotomy and inguinal orchiopexy. But, the meta-analyses do not recommend nor discard the use of prophylactic pre-operative antibiotics. The scarcity of controlled clinical trials in paediatric population further vitiates the matter. This study assessed the difference in the rate of early post-operative wound infection cases in children who received single dose of pre-operative antibiotics and children who did not receive antibiotics after inguinal herniotomy and orchiopexy. Materials and Methods: This randomised prospective study was conducted in Paediatric Surgery department of PGIMER Chandigarh. Out of 251 patients, 112 patients were randomised to the case group and 139 were ascribed to the control group. The patients in control group were given a standard regimen of single dose of intravenous antibiotic at the time of induction followed by 3-4 days of oral antibiotic. Case group patients underwent the surgical procedure in similar manner with no antibiotic either at the time of induction or post-operatively. Results: The incidence of surgical site infection in case group was 3.73 % and that in control group was 2.22%. The observed difference in the incidence of surgical site infection was statistically insignificant (P value = 0.7027. The overall infection rate in case and control group was 2.89%. Conclusions: Our preliminary experience suggests that there is no statistically significant difference in the proportion of early post-operative wound infection between the patients who received single dose of pre-operative antibiotics and the patients who received no antibiotics after inguinal herniotomy and orchiopexy. The risk of surgical site infection in paediatric heriotomies does not increase even if the child′s weight is less than his/her expected weight for age.

  4. Critical challenges in establishing emergency physician driven emergency departments – A Durban experience

    Directory of Open Access Journals (Sweden)

    R. Maharaj*

    2013-12-01

    The Western Cape experience has demonstrated the utility of an Emergency Physician led Emergency Department in improving the outcome of acute illness and trauma, which are strongly dependent on the early recognition of severity and the need for early intervention. We believe that a similar mind-set needs to be developed to service the increasing needs of the urban and peri-urban population served by eThekwini hospitals.

  5. Establishing the Transition to Turbulence in HED Shear Experiments on the NIF

    Science.gov (United States)

    Flippo, Kirk; Doss, F. W.; Kline, J. L.; Kot, L.; Perry, T. S.; Devolder, B.; Murphy, T. J.; Loomis, E. N.; Merritt, E. C.; Schmidt, D. W.; Capelli, D.; Cardenas, T.; Randolph, R. B.; Fierro, F.; Rivera, G.; Huntington, C. M.; Nagel, S. R.; MacLaren, S. A.

    2015-11-01

    We report on hydrodynamic experiments performed at the NIF to investigate turbulent mixing in a High Energy Density (HED) régime using the LANL Shock/Shear platform. We investigate turbulence-driven mix from a counter-propagating shear-flow induced Kelvin- Helmholtz instability. Such flows may be present in an ICF capsule that has low-mode asymmetries and bulk mixing of the shell into the fuel. In the NIF LANL Shear experiment two shocks are generated at either end of cylinder, inside which CH foams act as a light fluid and the evolution of a tracer layer (a ``heavy fluid'') in the center plane is imaged using the Big Area Backlighter (BABL), a large area x-ray backlighter, developed for this project. Edge views of the tracer layer are studied to quantify growth of the mix layer into the foam. Additionally, plan views (90-degrees to the edge view) are imaged to look at the complex hydrodynamic behavior of the foil, revealing coherent structures like rollers and wigglers similar to those seen in dye marker pure fluid shear experiments, features that can be made to evolve quickly into a state of randomness when the foil is roughened. Los Alamos National Laboratory is operated by the LANS, LLC for the NNSA of the U.S. DoE under contract DE-AC52-06NA25396.

  6. Establishing the Boundaries and Building Bridges: Research Methods Into the Ecology of the Refugee Parenting Experience

    Directory of Open Access Journals (Sweden)

    Nombasa Williams

    2010-10-01

    Full Text Available This article discusses the suitability of the focus group method for conducting research early in post-resettlement among refugee parents and carers in South Australia. This method was employed to uncover the refugee parenting experience in pre-resettlement contexts. There were three refugee focus groups, consisting of a Sudanese women’s group, an African men’s group, and an Afghani and Iraqi women’s group. To illustrate each group’s differential parenting ecologies in milieus of forced migration ecological matrixes were devised which are presented in the results section. An ecological matrix was also developed to unpack, code and analyse transcripts. The matrix was designed to include categories and actions so as to construct meaning units and subsequent condensed meaning units to determine the concluding themes. These provided an analytical framework with which to illuminate the constructed meanings participants attributed to their refugee parenting experiences. The findings provide insights into the ecology of the refugee parenting experience and might be of considerable importance for Australian resettlement services and state systems of child protection seeking to develop culturally appropriate and relevant services.

  7. Review. Establishing an experimental science of culture: animal social diffusion experiments.

    Science.gov (United States)

    Whiten, Andrew; Mesoudi, Alex

    2008-11-12

    A growing set of observational studies documenting putative cultural variations in wild animal populations has been complemented by experimental studies that can more rigorously distinguish between social and individual learning. However, these experiments typically examine only what one animal learns from another. Since the spread of culture is inherently a group-level phenomenon, greater validity can be achieved through 'diffusion experiments', in which founder behaviours are experimentally manipulated and their spread across multiple individuals tested. Here we review the existing corpus of 33 such studies in fishes, birds, rodents and primates and offer the first systematic analysis of the diversity of experimental designs that have arisen. We distinguish three main transmission designs and seven different experimental/control approaches, generating an array with 21 possible cells, 15 of which are currently represented by published studies. Most but not all of the adequately controlled diffusion experiments have provided robust evidence for cultural transmission in at least some taxa, with transmission spreading across populations of up to 24 individuals and along chains of up to 14 transmission events. We survey the achievements of this work, its prospects for the future and its relationship to diffusion studies with humans discussed in this theme issue and elsewhere.

  8. Establishing a clinical trials network in nephrology: experience of the Australasian Kidney Trials Network.

    Science.gov (United States)

    Morrish, Alicia T; Hawley, Carmel M; Johnson, David W; Badve, Sunil V; Perkovic, Vlado; Reidlinger, Donna M; Cass, Alan

    2014-01-01

    Chronic kidney disease is a major public health problem globally. Despite this, there are fewer high-quality, high-impact clinical trials in nephrology than other internal medicine specialties, which has led to large gaps in evidence. To address this deficiency, the Australasian Kidney Trials Network, a Collaborative Research Group, was formed in 2005. Since then, the Network has provided infrastructure and expertise to conduct patient-focused high-quality, investigator-initiated clinical trials in nephrology. The Network has not only been successful in engaging the nephrology community in Australia and New Zealand but also in forming collaborations with leading researchers from other countries. This article describes the establishment, development, and functions of the Network. The article also discusses the current and future funding strategies to ensure uninterrupted conduct of much needed clinical trials in nephrology to improve the outcomes of patients affected by kidney diseases with cost-effective interventions.

  9. Surveying rip current survivors: preliminary insights into the experiences of being caught in rip currents

    Science.gov (United States)

    Drozdzewski, D.; Shaw, W.; Dominey-Howes, D.; Brander, R.; Walton, T.; Gero, A.; Sherker, S.; Goff, J.; Edwick, B.

    2012-04-01

    This paper begins a process of addressing a significant gap in knowledge about people's responses to being caught in rip currents. While rip currents are the primary hazard facing recreational ocean swimmers in Australia, debate exists about the best advice to give swimmers caught in rip currents. Such surf rescue advice - on what to do and how to respond when caught in a rip - relies on empirical evidence. However, at present, knowledge about swimmers reactions and responses to rip currents is limited. This gap is a considerable barrier to providing effective advice to beach goers and to understanding how this advice is utilised (or not) when actually caught in the rip current. This paper reports the findings of a pilot study that focussed on garnering a better understanding of swimmers' experiences when caught in rip currents. A large scale questionnaire survey instrument generated data about rip current survivors' demographics, knowledge of beach safety and their reactions and responses when caught in a rip current. A mix of online and paper surveys produced a total of 671 completed surveys. Respondents were predominantly an informed group in terms of rip current knowledge, beach experience and had a high self-rated swimming ability. Preliminary insights from the survey show that most respondents recalled a "swim across the rip/parallel to the beach" message when caught in the rip and most escaped unassisted by acting on this message. However, while nearly a quarter of respondents recalled a message of "not to panic", short answer responses revealed that the onset of panic inhibited some respondents from recalling or enacting any other type of beach safety message when caught in the rip current. Results also showed that despite the research sample being younger, competent and frequent ocean swimmers, they were more likely to swim at unpatrolled beaches and outside of the red and yellow safety flags. Moreover, they were still caught in a rip current and they

  10. Preliminary experience in the management of tracheobronchial foreign bodies in Lagos, Nigeria.

    Science.gov (United States)

    Falase, Bode; Sanusi, Michael; Majekodunmi, Adetinuwe; Ajose, Ifeoluwa; Oke, David

    2013-01-01

    Aspiration of tracheobronchial foreign bodies commonly affects young children, is potentially life threatening and requires early intervention for extraction. Access to facilities and skill manpower for bronchoscopic extraction is however limited in Nigeria. The aim of this study is to describe the experience in our institution with bronchoscopic removal of tracheobronchial foreign bodies and highlight the challenges encountered. This is a retrospective study of all patients referred to the Lagos State University Teaching Hospital with a diagnosis of tracheobronchial foreign body within the period of February 2008 and February 2013. Data extracted from the medical records were age, sex, time interval between aspiration and presentation, location of tracheobronchial foreign body, bronchoscopic technique, complications and outcome. A total of 24 patients were referred and confirmed at bronchoscopy to have tracheobronchial foreign bodies. Mean age was 6.6 + 5 years. Male to female ratio was 1:1. Delayed presentation was common with 22 patients (91.7%) presenting more than 24 hours after aspiration. Aspirated material was inorganic in 17 patients (70.8%) and organic in 7 patients (29.2%). Location of tracheobronchial foreign bodies was right main bronchus in 16 patients (66.7%), left main bronchus in 6 patients (25%) and the trachea in 2 patients (8.3%). Challenges to speedy and safe removal of the foreign bodies were delayed presentation and a limited range of bronchoscopic equipment early in the series which caused prolonged procedures and increased complications. Two mortalities occurred early in the series; one from airway obstruction and the other from respiratory failure caused by tracheobronchial oedema. Extraction of tracheobronchial foreign bodies was faster, more complete and safer later in the series due to a wider range of bronchoscopy equipment which included both flexible and rigid videobronchoscopy with the use of optical forceps. This preliminary

  11. Surveying rip current survivors: preliminary insights into the experiences of being caught in rip currents

    Directory of Open Access Journals (Sweden)

    D. Drozdzewski

    2012-04-01

    Full Text Available This paper begins a process of addressing a significant gap in knowledge about people's responses to being caught in rip currents. While rip currents are the primary hazard facing recreational ocean swimmers in Australia, debate exists about the best advice to give swimmers caught in rip currents. Such surf rescue advice – on what to do and how to respond when caught in a rip – relies on empirical evidence. However, at present, knowledge about swimmers reactions and responses to rip currents is limited. This gap is a considerable barrier to providing effective advice to beach goers and to understanding how this advice is utilised (or not when actually caught in the rip current.

    This paper reports the findings of a pilot study that focussed on garnering a better understanding of swimmers' experiences when caught in rip currents. A large scale questionnaire survey instrument generated data about rip current survivors' demographics, knowledge of beach safety and their reactions and responses when caught in a rip current. A mix of online and paper surveys produced a total of 671 completed surveys. Respondents were predominantly an informed group in terms of rip current knowledge, beach experience and had a high self-rated swimming ability. Preliminary insights from the survey show that most respondents recalled a "swim across the rip/parallel to the beach" message when caught in the rip and most escaped unassisted by acting on this message. However, while nearly a quarter of respondents recalled a message of "not to panic", short answer responses revealed that the onset of panic inhibited some respondents from recalling or enacting any other type of beach safety message when caught in the rip current. Results also showed that despite the research sample being younger, competent and frequent ocean swimmers, they were more likely to swim at unpatrolled beaches and outside of the red and yellow safety flags. Moreover, they were still

  12. Geomorphic expression of strike-slip faults: field observations vs. analog experiments: preliminary results

    Science.gov (United States)

    Hsieh, S. Y.; Neubauer, F.; Genser, J.

    2012-04-01

    The aim of this project is to study the surface expression of strike-slip faults with main aim to find rules how these structures can be extrapolated to depth. In the first step, several basic properties of the fault architecture are in focus: (1) Is it possible to define the fault architecture by studying surface structures of the damage zone vs. the fault core, particularly the width of the damage zone? (2) Which second order structures define the damage zone of strike-slip faults, and how relate these to such reported in basement fault strike-slip analog experiments? (3) Beside classical fault bend structures, is there a systematic along-strike variation of the damage zone width and to which properties relates the variation of the damage zone width. We study the above mentioned properties on the dextral Altyn fault, which is one of the largest strike-slip on Earth with the advantage to have developed in a fully arid climate. The Altyn fault includes a ca. 250 to 600 m wide fault valley, usually with the trace of actual fault in its center. The fault valley is confined by basement highs, from which alluvial fans develop towards the center of the fault valley. The active fault trace is marked by small scale pressure ridges and offset of alluvial fans. The fault valley confining basement highs are several kilometer long and ca. 0.5 to 1 km wide and confined by rotated dextral anti-Riedel faults and internally structured by a regular fracture pattern. Dextral anti-Riedel faults are often cut by Riedel faults. Consequently, the Altyn fault comprises a several km wide damage zone. The fault core zone is a barrier to fluid flow, and the few springs of the region are located on the margin of the fault valley implying the fractured basement highs as the reservoir. Consequently, the southern Silk Road was using the Altyn fault valley. The preliminary data show that two or more orders of structures exist. Small-scale develop during a single earthquake. These finally

  13. Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience.

    Science.gov (United States)

    De Sousa, Paul A; Steeg, Rachel; Wachter, Elisabeth; Bruce, Kevin; King, Jason; Hoeve, Marieke; Khadun, Shalinee; McConnachie, George; Holder, Julie; Kurtz, Andreas; Seltmann, Stefanie; Dewender, Johannes; Reimann, Sascha; Stacey, Glyn; O'Shea, Orla; Chapman, Charlotte; Healy, Lyn; Zimmermann, Heiko; Bolton, Bryan; Rawat, Trisha; Atkin, Isobel; Veiga, Anna; Kuebler, Bernd; Serano, Blanca Miranda; Saric, Tomo; Hescheler, Jürgen; Brüstle, Oliver; Peitz, Michael; Thiele, Cornelia; Geijsen, Niels; Holst, Bjørn; Clausen, Christian; Lako, Majlinda; Armstrong, Lyle; Gupta, Shailesh K; Kvist, Alexander J; Hicks, Ryan; Jonebring, Anna; Brolén, Gabriella; Ebneth, Andreas; Cabrera-Socorro, Alfredo; Foerch, Patrik; Geraerts, Martine; Stummann, Tina C; Harmon, Shawn; George, Carol; Streeter, Ian; Clarke, Laura; Parkinson, Helen; Harrison, Peter W; Faulconbridge, Adam; Cherubin, Luca; Burdett, Tony; Trigueros, Cesar; Patel, Minal J; Lucas, Christa; Hardy, Barry; Predan, Rok; Dokler, Joh; Brajnik, Maja; Keminer, Oliver; Pless, Ole; Gribbon, Philip; Claussen, Carsten; Ringwald, Annette; Kreisel, Beate; Courtney, Aidan; Allsopp, Timothy E

    2017-04-01

    A fast track "Hot Start" process was implemented to launch the European Bank for Induced Pluripotent Stem Cells (EBiSC) to provide early release of a range of established control and disease linked human induced pluripotent stem cell (hiPSC) lines. Established practice amongst consortium members was surveyed to arrive at harmonised and publically accessible Standard Operations Procedures (SOPs) for tissue procurement, bio-sample tracking, iPSC expansion, cryopreservation, qualification and distribution to the research community. These were implemented to create a quality managed foundational collection of lines and associated data made available for distribution. Here we report on the successful outcome of this experience and work flow for banking and facilitating access to an otherwise disparate European resource, with lessons to benefit the international research community. ETOC: The report focuses on the EBiSC experience of rapidly establishing an operational capacity to procure, bank and distribute a foundational collection of established hiPSC lines. It validates the feasibility and defines the challenges of harnessing and integrating the capability and productivity of centres across Europe using commonly available resources currently in the field. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  14. Establishing a health demographic surveillance site in Bhaktapur district, Nepal: initial experiences and findings

    Directory of Open Access Journals (Sweden)

    Aryal Umesh

    2012-09-01

    Full Text Available Abstract Background A health demographic surveillance system (HDSS provides longitudinal data regarding health and demography in countries with coverage error and poor quality data on vital registration systems due to lack of public awareness, inadequate legal basis and limited use of data in health planning. The health system in Nepal, a low-income country, does not focus primarily on health registration, and does not conduct regular health data collection. This study aimed to initiate and establish the first HDSS in Nepal. Results We conducted a baseline survey in Jhaukhel and Duwakot, two villages in Bhaktapur district. The study surveyed 2,712 households comprising a total population of 13,669. The sex ratio in the study area was 101 males per 100 females and the average household size was 5. The crude birth and death rates were 9.7 and 3.9/1,000 population/year, respectively. About 11% of births occurred at home, and we found no mortality in infants and children less than 5 years of age. Various health problems were found commonly and some of them include respiratory problems (41.9%; headache, vertigo and dizziness (16.7%; bone and joint pain (14.4%; gastrointestinal problems (13.9%; heart disease, including hypertension (8.8%; accidents and injuries (2.9%; and diabetes mellitus (2.6%. The prevalence of non-communicable disease (NCD was 4.3% (95% CI: 3.83; 4.86 among individuals older than 30 years. Age-adjusted odds ratios showed that risk factors, such as sex, ethnic group, occupation and education, associated with NCD. Conclusion Our baseline survey demonstrated that it is possible to collect accurate and reliable data in a village setting in Nepal, and this study successfully established an HDSS site. We determined that both maternal and child health are better in the surveillance site compared to the entire country. Risk factors associated with NCDs dominated morbidity and mortality patterns.

  15. The establishment of endovascular aneurysm coiling at a neurovascular unit: report of experience during early years.

    Science.gov (United States)

    Norbäck, O; Gál, G; Johansson, M; Solander, S; Tovi, M; Persson, L; Ronne-Engström, E; Enblad, P

    2005-02-01

    The treatment of cerebral aneurysms is changing from surgical clipping to endovascular coiling (EVC) in many neurovascular centres. The aim of this study was to evaluate the technical results and clinical outcome at 6 months in a consecutive series of subarachnoid hemorrhage (SAH) patients treated with EVC, in a situation when the EVC had been established very rapidly as the first line of treatment at a neurovascular centre. The patient material comprised 239 SAH patients (155 women and 84 men, mean age 55 years, age range 16-81) allocated to EVC as the first line of treatment in the acute stage (within 3 weeks of rupture) between September 1996 and December 2000. Clinical grade on admission was Hunt & Hess (H&H) I and II in 42%, H&H III in 25% and H&H grade IV and V in 33% of the patients. The aneurysm was located in the anterior circulation in 82% of the cases. EVC was performed on days 0-3 in 77% of the cases. EVC of the target aneurysm was able to be completed in 222 patients (93%). Complete occlusion was achieved in 126 patients (53%). Procedural complications occurred in 39 patients (16%). Favourable clinical outcome was observed in 57%, severe disability in 28% and poor outcome in 14% of the patients. Favourable outcome was achieved in 77% of H&H I and II patients and in 43% of H&H III-V patients. The multivariate logistic regression analysis revealed that younger age, good neurological grade on admission, absence of intracerebral hematoma and intraventricular hematoma respectively, ICA-PcomA aneurysm location, later treatment and absence of complications were significant predictors of favourable outcome. After interventional training and installation of the X-ray system, the introduction and establishment of EVC at a neurovascular unit can be done in a short period of time and with favourable results. Future studies must concentrate on identifying factors of importance for the choice of interventional or surgical therapy. The results of this study indicate

  16. Cosmic Experiments: Remaking Materialism and Daoist Ethic "Outside of the Establishment".

    Science.gov (United States)

    Zhan, Mei

    2016-01-01

    In this article, I discuss recent experiments in 'classical' (gudian) Chinese medicine. As the marketization and privatization of health care deepens and enters uncharted territories in China, a cohort of young practitioners and entrepreneurs have begun their quest for the 'primordial spirit' of traditional Chinese medicine by setting up their own businesses where they engage in clinical, pedagogical, and entrepreneurial practices outside of state-run institutions. I argue that these explorations in classical Chinese medicine, which focus on classical texts and Daoist analytics, do not aim to restore spirituality to the scientized and secularized theory of traditional Chinese medicine. Nor are they symptomatic of withdrawals from the modern world. Rather, these 'cosmic experiments' need to be understood in relation to dialectical and historical materialisms as modes of knowledge production and political alliance. In challenging the status of materialist theory and the process of theorization in traditional Chinese medicine and postsocialist life more broadly speaking, advocates of classical Chinese medicine imagine nondialectical materialisms as immanent ways of thinking, doing, and being in the world.

  17. Establishing cytogenetic biodosimetry laboratory in Saudi Arabia and producing preliminary calibration curve of dicentric chromosomes as biomarker for medical dose estimation in response to radiation emergencies.

    Science.gov (United States)

    Al-Hadyan, Khaled; Elewisy, Sara; Moftah, Belal; Shoukri, Mohamed; Alzahrany, Awad; Alsbeih, Ghazi

    2014-12-01

    In cases of public or occupational radiation overexposure and eventual radiological accidents, it is important to provide dose assessment, medical triage, diagnoses and treatment to victims. Cytogenetic bio-dosimetry based on scoring of dicentric chromosomal aberrations assay (DCA) is the "gold standard" biotechnology technique for estimating medically relevant radiation doses. Under the auspices of the National Science, Technology and Innovation Plan in Saudi Arabia, we have set up a biodosimetry laboratory and produced a national standard dose-response calibration curve for DCA, pre-required to estimate the doses received. For this, the basic cytogenetic DCA technique needed to be established. Peripheral blood lymphocytes were collected from four healthy volunteers and irradiated with radiation doses between 0 and 5 Gy of 320 keV X-rays. Then, lymphocytes were PHA stimulated, Colcemid division arrested and stained cytogenetic slides were prepared. The Metafer4 system (MetaSystem) was used for automatic and manually assisted metaphase finding and scoring of dicentric chromosomes. Results were fit to the linear-quadratic dose-effect model according to the IAEA EPR-Biodosimetry-2011 report. The resulting manually assisted dose-response calibration curve (Y = 0.0017 + 0.026 × D + 0.081 × D(2)) was in the range of those described in other populations. Although the automated scoring over-and-under estimates DCA at low (2 Gy) doses, respectively, it showed potential for use in triage mode to segregate between victims with potential risk to develop acute radiotoxicity syndromes. In conclusion, we have successfully established the first biodosimetry laboratory in the region and have produced a preliminary national dose-response calibration curve. The laboratory can now contribute to the national preparedness plan in response to eventual radiation emergencies in addition to providing information for decision makers and public health officials who assess the

  18. Establishment of an operational system for drug profiling: a Swiss experience.

    Science.gov (United States)

    Ioset, S; Esseiva, P; Ribaux, O; Weyermann, C; Anglada, F; Lociciro, S; Hayoz, P; Baer, I; Gasté, L; Terrettaz-Zufferey, A L; Delaporte, C; Margot, P

    2005-01-01

    The present article describes the profiling process developed at the Institute of Forensic Science of the School of Crime Sciences of the Faculty of Law at the University of Lausanne. The technique is oriented towards an operational approach that can be applied directly by drug units of local law enforcement authorities. The background of the development of that technique and issues relating to data sources are outlined. Analytical, statistical and computerized methods for detecting, managing and visualizing linkages are examined in the context of drug profiling. Harmonization of methods and operational use of links are discussed and explained using examples. Finally, adequate communication of forensic information/intelligence is explored as an area of development. This endeavour has helped demonstrate the enormous potential that linking seizures made in different regional markets has for police investigations. The next stage is to focus on implementing this model in a more systematic manner and, if possible, at the national level and even the international level. That harmonization of methods should be pursued in order to maximize the potential of the detected linkages. In conclusion, links established through profiling, combined with traditional information, can be utilized to better understand the market's structure and implement medium- and long-term investigation strategies.

  19. Arithmetic memory networks established in childhood are changed by experience in adulthood.

    Science.gov (United States)

    Martinez-Lincoln, Amanda; Cortinas, Christina; Wicha, Nicole Y Y

    2015-01-01

    Adult bilinguals show stronger access to multiplication tables when using the language in which they learned arithmetic during childhood (LA+) than the other language (LA-), implying language-specific encoding of math facts. However, most bilinguals use LA+ throughout their life, confounding the impact of encoding and use. We tested if using arithmetic facts in LA- could reduce this LA- disadvantage. We measured event related brain potentials while bilingual teachers judged the correctness of multiplication problems in each of their languages. Critically, each teacher taught arithmetic in either LA+ or LA-. Earlier N400 peak latency was observed in both groups for the teaching than non-teaching language, showing more efficient access to these facts with use. LA+ teachers maintained an LA+ advantage, while LA- teachers showed equivalent N400 congruency effects (for incorrect versus correct solutions) in both languages. LA- teachers also showed a late positive component that may reflect conflict monitoring between their LA+ and a strong LA-. Thus, the LA- disadvantage for exact arithmetic established in early bilingual education can be mitigated by later use of LA-.

  20. Preliminary experiments to estimate the PE.MA.M (PElagic MArine Mesocosm) offshore behaviour

    Science.gov (United States)

    Albani, Marta; Piermattei, Viviana; Stefanì, Chiara; Marcelli, Marco

    2016-04-01

    The phytoplankton community is controlled not only by local environmental conditions but also by physical processes occurring on different temporal and spatial scales. Hydrodynamic local conditions play an important role in marine ecosystems. Several studies have shown that hydrodynamic conditions can influence the phytoplankton settling velocity, vertical and horizontal distribution and formation of cyanobacterial blooms. Mesocosms are useful structures to simulate marine environment at mesoscale resolution; allowing to closely approximate biotic or abiotic parameters of interest directly in nature. In this work an innovative structure named PE.MA.M (PElagic MArine Mesocosm) is presented and tested. Laboratory experiments have been conducted in order to observe seasonal variations of biomass behaviour in two different hydrodynamic conditions: outside as well as whithin the PE.MA.M. We have evaluated whether it is possible to isolate a natural system from external water mass hydrodynamic exchanges and to assume that phytoplankton cells' transition is limited at the net and sea interface. Preliminary experiments test the isolating capacity of the net, to determine the currents' attenuation rate and to estimate the possible PE.MA.M. offshore behaviour. In the first investigation, we monitored the diffusion of phytoplankton cells. The PE.MA.M. exterior and interior were simulated using a plexiglass tank divided into two half-tanks (Aout-Bin) by a septum consisting of a net like a PE.MA.M. The tank was filled up with 10 L of water and only the half-tank Aout was filled up with 10 ml of phytoplankton culture (Clorella sp.). We monitored the chlorophyll concentrations for 24 hours. The two tanks had similar concentrations after 4 hours (2.70322 mg/m³ Aout and 2.37245 mg/m3 Bin) and this constant relationship was maintened until the end of the test. In the second investigation we used clod cards to measure water motions.We conducted two experiments within tank, the first

  1. Progress on Establishing Guidelines for National Ignition Facility (NIF) Experiments to Extend Debris Shield Lifetime

    Energy Technology Data Exchange (ETDEWEB)

    Tobin, M; Eder, D; Braun, D; MacGowan, B

    2000-07-26

    The survivability and performance of the debris shields on the National Ignition Facility (NIF) are a key factor for the successful conduct and affordable operation of the facility. The improvements required over Nova debris shields are described. Estimates of debris shield lifetimes in the presence of target emissions with 4 - 5 J/cm{sup 2} laser fluences (and higher) indicate lifetimes that may contribute unacceptably to operations costs for NIF. We are developing detailed guidance for target and experiment designers for NIF to assist in minimizing the damage to, and therefore the cost of, maintaining NIF debris shields. The guidance limits the target mass that is allowed to become particulate on the debris shields (300 mg). It also limits the amount of material that can become shrapnel for any given shot (10 mg). Finally, it restricts the introduction of non-volatile residue (NVR) that is a threat to the sol-gel coatings on the debris shields to ensure that the chamber loading at any time is less than 1 pg/cm{sup 2}. We review the experimentation on the Nova chamber that included measuring quantities of particulate on debris shields by element and capturing shrapnel pieces in aerogel samples mounted in the chamber. We also describe computations of x-ray emissions from a likely NIF target and the associated ablation expected from this x-ray exposure on supporting target hardware. We describe progress in assessing the benefits of a pre-shield and the possible impact on the guidance for target experiments on NIF. Plans for possible experimentation on Omega and other facilities to improve our understanding of target emissions and their impacts are discussed. Our discussion of planned future work provides a forum to invite possible collaboration with the IFE community.

  2. Use of movable high-field-strength intraoperative magnetic resonance imaging with awake craniotomies for resection of gliomas: preliminary experience.

    LENUS (Irish Health Repository)

    Leuthardt, Eric C

    2011-07-01

    Awake craniotomy with electrocortical mapping and intraoperative magnetic resonance imaging (iMRI) are established techniques for maximizing tumor resection and preserving function, but there has been little experience combining these methodologies.

  3. Establishing specialized health services for professional consultation in euthanasia: experiences in the Netherlands and Belgium

    Science.gov (United States)

    2009-01-01

    Background The Netherlands, Belgium, and Luxembourg have adopted laws decriminalizing euthanasia under strict conditions of prudent practice. These laws stipulate, among other things, that the attending physician should consult an independent colleague to judge whether the substantive criteria of due care have been met. In this context initiatives were taken in the Netherlands and Belgium to establish specialized services providing such consultants: Support and Consultation for Euthanasia in the Netherlands (SCEN) and Life End Information Forum (LEIF) in Belgium. The aim of this study is to describe and compare these initiatives. Methods We studied and compared relevant documents concerning the Dutch and Belgian consultation service (e.g. articles of bye-laws, inventories of activities, training books, consultation protocols). Results In both countries, the consultation services are delivered by trained physicians who can be consulted in cases of a request for euthanasia and who offer support and information to attending physicians. The context in which the two organisations were founded, as well as the way they are organised and regulated, is different in each country. By providing information on all end-of-life care matters, the Belgian LEIF seems to have a broader consultation role than the Dutch SCEN. SCEN on the other hand has a longer history, is more regulated and organised on a larger scale and receives more government funding than LEIF. The number of training hours for physicians is equal. However, SCEN-training puts more emphasis on the consultation report, whereas LEIF-training primarily emphasizes the ethical framework of end-of-life decisions. Conclusion In case of a request for euthanasia, in the Netherlands as well as in Belgium similar consultation services by independent qualified physicians have been developed. In countries where legalising physician-assisted death is being contemplated, the development of such a consultation provision could also

  4. Establishing specialized health services for professional consultation in euthanasia: experiences in the Netherlands and Belgium.

    Science.gov (United States)

    Van Wesemael, Yanna; Cohen, Joachim; Onwuteaka-Philipsen, Bregje D; Bilsen, Johan; Deliens, Luc

    2009-12-04

    The Netherlands, Belgium, and Luxembourg have adopted laws decriminalizing euthanasia under strict conditions of prudent practice. These laws stipulate, among other things, that the attending physician should consult an independent colleague to judge whether the substantive criteria of due care have been met. In this context initiatives were taken in the Netherlands and Belgium to establish specialized services providing such consultants: Support and Consultation for Euthanasia in the Netherlands (SCEN) and Life End Information Forum (LEIF) in Belgium. The aim of this study is to describe and compare these initiatives. We studied and compared relevant documents concerning the Dutch and Belgian consultation service (e.g. articles of bye-laws, inventories of activities, training books, consultation protocols). In both countries, the consultation services are delivered by trained physicians who can be consulted in cases of a request for euthanasia and who offer support and information to attending physicians. The context in which the two organisations were founded, as well as the way they are organised and regulated, is different in each country. By providing information on all end-of-life care matters, the Belgian LEIF seems to have a broader consultation role than the Dutch SCEN. SCEN on the other hand has a longer history, is more regulated and organised on a larger scale and receives more government funding than LEIF. The number of training hours for physicians is equal. However, SCEN-training puts more emphasis on the consultation report, whereas LEIF-training primarily emphasizes the ethical framework of end-of-life decisions. In case of a request for euthanasia, in the Netherlands as well as in Belgium similar consultation services by independent qualified physicians have been developed. In countries where legalising physician-assisted death is being contemplated, the development of such a consultation provision could also be considered in order to safeguard

  5. Establishing specialized health services for professional consultation in euthanasia: experiences in the Netherlands and Belgium

    Directory of Open Access Journals (Sweden)

    Bilsen Johan

    2009-12-01

    Full Text Available Abstract Background The Netherlands, Belgium, and Luxembourg have adopted laws decriminalizing euthanasia under strict conditions of prudent practice. These laws stipulate, among other things, that the attending physician should consult an independent colleague to judge whether the substantive criteria of due care have been met. In this context initiatives were taken in the Netherlands and Belgium to establish specialized services providing such consultants: Support and Consultation for Euthanasia in the Netherlands (SCEN and Life End Information Forum (LEIF in Belgium. The aim of this study is to describe and compare these initiatives. Methods We studied and compared relevant documents concerning the Dutch and Belgian consultation service (e.g. articles of bye-laws, inventories of activities, training books, consultation protocols. Results In both countries, the consultation services are delivered by trained physicians who can be consulted in cases of a request for euthanasia and who offer support and information to attending physicians. The context in which the two organisations were founded, as well as the way they are organised and regulated, is different in each country. By providing information on all end-of-life care matters, the Belgian LEIF seems to have a broader consultation role than the Dutch SCEN. SCEN on the other hand has a longer history, is more regulated and organised on a larger scale and receives more government funding than LEIF. The number of training hours for physicians is equal. However, SCEN-training puts more emphasis on the consultation report, whereas LEIF-training primarily emphasizes the ethical framework of end-of-life decisions. Conclusion In case of a request for euthanasia, in the Netherlands as well as in Belgium similar consultation services by independent qualified physicians have been developed. In countries where legalising physician-assisted death is being contemplated, the development of such a

  6. Aligned short-fibre reinforced thermosets - Experiments and analysis lend little support for established theory

    Science.gov (United States)

    Piggott, M. R.; Ko, M.; Chuang, H. Y.

    Experiments with epoxy resins reinforced with aligned short carbon fibers give results which disagree sharply with traditional fiber reinforcement theory based on interface yielding and slip and the concept of the critical fiber aspect ratio. Earlier results and evidence from interface studies are therefore reviewed, and it is shown that, as the carbon/polymer interface is brittle, the progressive interface failure process previously envisaged almost certainly does not take place. Furthermore, a careful reading of the sources of data relating to the yielding and slip theory indicates that the evidence in support of it is very weak. Thus, the idea of the critical fiber aspect ratio, borrowed from the metallurgists, may not be appropriate for short-fiber reinforced plastics. Instead, a process involving brittle fiber debonds should be considered. These debonds could trigger matrix cracking and hence explain the anomalously low composite breaking strains observed when the breaking strain of the fiber is greater than that of the polymer, and other properties of aligned short-fiber composites.

  7. Preliminary planning study for safety relief valve experiments in a Mark III BWR pressure suppression system

    Energy Technology Data Exchange (ETDEWEB)

    McCauley, E.W.; Holman, G.S.

    1980-04-21

    In response to a request from the Water Reactor Safety Research Division of the US NRC, a preliminary study is provided which identifies key features and consideration involved in planning a comprehensive in-plant Safety Relief Valve experimental program for a Mark III containment design. The report provides identification of program objectives, measurement system requirements, and some details quantifying expected system response. In addition, a preliminary test matrix is outlined which involves a supporting philosophy intended to enhance the usefulness of the experimental results for all members of the program team: experimentalists, analysts, and plant operator.

  8. A new extra-abdominal channel alternative to the mitrofanoff principle: experimental and preliminary clinical experience

    Directory of Open Access Journals (Sweden)

    Antonio Macedo Jr.

    2009-04-01

    Full Text Available INTRODUCTION: The appendix is the gold-standard channel for the Mitrofanoff principle in pediatric urology, but the search for alternatives is justified considering it may not be available or preferably used for colonic stomas (Malone antegrade continence enema. The aim of this study is to report on technical feasibility of a new approach for creating catheterizable channels in a rabbit model and to present our preliminary clinical experience. MATERIAL AND METHODS: We configured a tube from two rectangular skin flaps 1x4 cm opposite each other in the middle line of the lower inferior abdomen. The channel was anastomosed to the bladder dome with embedding sutures to create a valvular mechanism. The experimental study consisted of 12 rabbits, divided in 4 groups according to the sacrifice schedule at 2, 4, 8 and 12 weeks. At 30th postoperative day, an urodynamic evaluation was performed to record continence of the stoma. A histological analysis of the specimens stained with hematoxylin-eosin, Masson trichrome and Picrosirius red was also done in group 2 (sacrifice at 4 weeks postoperatively. We used this method in 3 patients with congenital non-neurogenic bladder disease presenting with massive residual volumes without compliance deficits. RESULT: The technique proved feasible in all animals, 9 of 12 could be easily catheterized and underwent urodynamic study. No stoma leakage was observed in 7 animals at high bladder pressures (> 50 cm H20 and only 2 animals had some leakage at 40 cm H20. Urodynamics performed through the stoma showed urethral leakage at 20 cm H20, therefore demonstrating the efficacy of the valvular mechanism. Histological analysis confirmed good integration between the tube and the bladder. Mean follow-up of the clinical series (3 patients was 7.2 months. Two patients remained continent up to 4 hours, whereas 1 patient had some leakage after 2 hours. CONCLUSION: We were able to confirm feasibility of a new extra

  9. Only fixation for cervical spondylosis: Report of early results with a preliminary experience with 6 cases

    Directory of Open Access Journals (Sweden)

    Atul Goel

    2013-01-01

    Full Text Available Aim: The author reports early post-operative outcome and preliminary experience with an alternative form of treatment of cervical degenerative or spondylotic disease leading to spinal canal stenosis that involves fixation-arthrodesis of the affected spinal segment using one or two (double insurance transarticular screws for each joint. Materials and Methods: During the period of months from March 2013 to July 2013, six patients having cervical spondylotic cord compression were treated with transarticular method of screw fixation of the involved segments. The operation involved section of the spinous process at its base, opening up of the facet joint, denuding of articular cartilage, placement of intraarticular cavity bone graft chips and insertion of either a single or two transarticular screws at each level. The fixation was done in four levels in four patients and at two levels in two patients. Japanese Orthopedic Association score, visual analog scale (neck pain and Odom′s criteria were used to monitor the clinical status of the patients before and after the surgery and at follow-up. Results: Immediate post-operative and a relatively short-term post-operative outcome was remarkably gratifying. During the average period of follow-up of 6 months (range: 3-8 months; there was varying degree of recovery of symptoms. The procedure resulted in firm stabilization and fixation of the spinal segment and provided a ground for arthrodesis. No patient worsened after treatment. During the period of follow-up, all patients showed remarkable and progressive recovery in symptoms. Conclusions: Vertical instability and telescoping, listhesis or overriding of the facets on physical activity seems to be the defining phenomenon in pathogenesis of cervical spondylotic disease. The clinical outcome in our patients suggest that only fixation of the spinal segment can be a rationale form of treatment. Transarticular method of treatment is a simple, safe and

  10. Preliminary data for the 20 May 1974, simultaneous evaluation of remote sensors experiment. [water pollution monitoring

    Science.gov (United States)

    Johnson, R. W.; Batten, C. E.; Bowker, D. E.; Bressette, W. E.; Grew, G. W.

    1975-01-01

    Several remote sensors were simultaneously used to collect data over the tidal James River from Hopewell to Norfolk, Virginia. Sensors evaluated included the Multichannel-Ocean Color Sensor, multispectral scanners, and multispectral photography. Ground truth measurements and remotely sensed data are given. Preliminary analysis indicates that suspended sediment and concentrated industrial effluent are observable from all sensors.

  11. Wearable ultrasonic guiding device with white cane for the visually impaired: A preliminary verisimilitude experiment.

    Science.gov (United States)

    Cheng, Po-Hsun

    2016-01-01

    Several assistive technologies are available to help visually impaired individuals avoid obstructions while walking. Unfortunately, white canes and medical walkers are unable to detect obstacles on the road or react to encumbrances located above the waist. In this study, I adopted the cyber-physical system approach in the development of a cap-connected device to compensate for gaps in detection associated with conventional aids for the visually impaired. I developed a verisimilar, experimental route involving the participation of seven individuals with visual impairment, including straight sections, left turns, right turns, curves, and suspended objects. My aim was to facilitate the collection of information required for the practical use of the device. My findings demonstrate the feasibility of the proposed guiding device in alerting walkers to the presence of some kinds of obstacles from the small number of subjects. That is, it shows promise for future work and research with the proposed device. My findings provide a valuable reference for the further improvement of these devices as well as the establishment of experiments involving the visually impaired.

  12. Towards a quantitative study of the VUV photolysis of methane: preliminary experiment on trichloromethane

    Science.gov (United States)

    Gans, B.; Boyé-Péronne, S.; Douin, S.; Gauyacq, D.

    2010-01-01

    Photolysis of methane in Titan's stratosphere is the starting point of gas phase carbon chemistry. Quantitative studies of methane photolytic products are of utmost importance for Titan atmosphere models. With this aim, two experimental strategies are presented in this article. Preliminary results demonstrate the possibility of using CRDS absorption coupled with pulsed photolysis on the example of a halogenated derivative of methane: Trichloromethane (CHCl_3).

  13. Mass transport phenomena during solidification in microgravity; preliminary results of the first Mephisto flight experiment

    Science.gov (United States)

    Favier, J. J.; Garandet, J. P.; Rouzaud, A.; Camel, D.

    1994-06-01

    The MEPHISTO space facility flew on the Columbia space shuttle in October 1992. The preliminary scientific results, mainly based on the analysis of the Seebeck signal, are presented in this paper. Valuable information was obtained for both planar and cellular solidification regimes. It is shown that mass transfer in the melt during the flight was principally diffusive; however, even in microgravity, slow growth rates may result in significant convective transport. A tentative interpretation of the Seebeck signal for destabilized interfaces is also proposed.

  14. Preliminary results of Resistive Plate Chambers operated with eco-friendly gas mixtures for application in the CMS experiment

    CERN Document Server

    Abbrescia, M

    2016-01-01

    The operations of Resistive Plate Chambers in LHC experiments require Fluorine based (F-based) gases for optimal performance. Recent European regulations demand the use of environmentally unfriendly F-based gases to be limited or banned. In view of the CMS experiment upgrade, several tests are ongoing to measure the performance of the detector with these new ecological gas mixtures, in terms of efficiency, streamer probability, induced charge and time resolution. Prototype chambers with readout pads and with the standard CMS electronic setup are under test. In this paper preliminary results on performance of RPCs operated with a potential eco-friendly gas candidate 1,3,3,3-Tetrafluoropropene, commercially known as HFO-1234ze, with CO2 and CF3I based gas mixtures are presented and discussed for the possible application in the CMS experiment.

  15. Preliminary results of Resistive Plate Chambers operated with eco-friendly gas mixtures for application in the CMS experiment

    CERN Document Server

    Abbrescia, Marcello; Benussi, Luigi; Bianco, Stefano; Cauwenbergh, Simon Marc D; Ferrini, Mauro; Muhammad, Saleh; Passamontic, L; Pierluigi, Daniele; Piccolo, Davide; Primavera, Federica; Russo, Alessandro; Savianoc, G; Tytgat, Michael

    2016-01-01

    The operations of Resistive Plate Chambers in LHC experiments require F-based gases for optimal performance. Recent regulations demand the use of environmentally unfriendly F-based gases to be limited or banned. In view of the CMS experiment upgrade several tests are ongoing to measure the performance of the detector in terms of efficiency, streamer probability, induced charge and time resolution. Prototype chambers with readout pads and with the standard cms electronic setup are under test. In this talk preliminary results on performance of RPCs operated with a potential eco-friendly gas candidate 1,3,3,3-Tetrafluoropropene, commercially known as HFO-1234ze and with CO2 based gas mixtures are presented and discussed for the possible application in the CMS experiment.

  16. The Thirty Gigahertz Instrument Receiver for the QUIJOTE Experiment: Preliminary Polarization Measurements and Systematic-Error Analysis.

    Science.gov (United States)

    Casas, Francisco J; Ortiz, David; Villa, Enrique; Cano, Juan L; Cagigas, Jaime; Pérez, Ana R; Aja, Beatriz; Terán, J Vicente; de la Fuente, Luisa; Artal, Eduardo; Hoyland, Roger; Génova-Santos, Ricardo

    2015-08-05

    This paper presents preliminary polarization measurements and systematic-error characterization of the Thirty Gigahertz Instrument receiver developed for the QUIJOTE experiment. The instrument has been designed to measure the polarization of Cosmic Microwave Background radiation from the sky, obtaining the Q, U, and I Stokes parameters of the incoming signal simultaneously. Two kinds of linearly polarized input signals have been used as excitations in the polarimeter measurement tests in the laboratory; these show consistent results in terms of the Stokes parameters obtained. A measurement-based systematic-error characterization technique has been used in order to determine the possible sources of instrumental errors and to assist in the polarimeter calibration process.

  17. A Preliminary Study on 1D Numerical Experiment of Water Debris Flow in Gully

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    In order to improve and enhance the numerical modeling methods and its application on debris flow problems,a preliminary study has been proposed in accordance with the corrected water-sediment numerical model on the premise of revised resistance and sediment capacity equations.Firstly,an overview the recent re- search achievements on numerical simulation of debris flow has been conducted,the results shown that a gener- al numerical model for debris flow can not be existed at all because the complex rheol...

  18. Rapid screening of wheat bran contaminated by deoxynivalenol mycotoxin using Raman spectroscopy: a preliminary experiment

    Science.gov (United States)

    Mignani, A. G.; Ciaccheri, L.; Mencaglia, A. A.; De Girolamo, A.; Lippolis, V.; Pascale, M.

    2016-05-01

    Deoxynivalenol (DON) is a mycotoxin frequently occurring in cereals and derived products, and regulated in many countries. Raman spectroscopy performed using optical fibers, with excitation at 1064 nm and a dispersive detection scheme, was utilized to analyze wheat bran samples naturally contaminated with DON. A multivariate processing of the spectroscopic data allowed to distinguish two classes of contamination, with DON below and above 400 μg/kg, respectively. Only one highly contaminated sample was misclassified. This preliminary result demonstrates the potential of Raman spectroscopy as a useful analytical tool for the non-destructive and rapid analysis of mycotoxins in food.

  19. Frictional sliding in layered rock model: Preliminary experiments. Yucca Mountain Site Characterization Project

    Energy Technology Data Exchange (ETDEWEB)

    Perry, K.E. Jr.; Buescher, B.J.; Anderson, D.; Epstein, J.S. [Idaho National Engineering Lab., Idaho Falls, ID (United States)

    1995-09-01

    An important aspect of determining the suitability of Yucca Mountain as a possible nuclear waste repository requires understanding the mechanical behavior of jointed rock-masses. To this end we have studied the frictional sliding between simulated rock joints in the laboratory using the technique of phase shifting moire interferometry. The models were made from stacks of Lexan plates and contained a central hole to induce slip between the plates when the models were loaded in compression. These preliminary results confirm the feasibility of the approach and show a clear evolution of slip as function of load.

  20. Mass transport phenomena in microgravity: Preliminary results of the first MEPHISTO flight experiment

    Science.gov (United States)

    Favier, Jean Jacques; Garandet, J. P.; Rouzaud, A.; Camel, D.

    1994-01-01

    The MEPHISTO space program is the result of a cooperative effort that involves the French nuclear and space agencies (Commissariat a l'energie atomique, CEA - Centre National d'Etudes Spatiales, CNES) and the American National Aeronautics and Space Administration (NASA). The scientific studies and apparatus development were funded in the frame of the GRAMME agreement between CEA and CNES, the flight costs being taken in charge by NASA. Six flight opportunities are scheduled, with alternating French and American principal investigators. It is the purpose of this paper to briefly present MEPHISTO along with the preliminary results obtained during its first flight on USMP-1 in October 1992.

  1. MR imaging of prostate. Preliminary experience with calculated imaging in 28 cases

    Energy Technology Data Exchange (ETDEWEB)

    Gevenois, P.A.; Van Regemorter, G.; Ghysels, M.; Delepaut, A.; Van Gansbeke, D.; Struyven, J.

    1988-04-01

    The majority of studies with MR imaging in prostate disease are based on a semiology obtained using images weighted in T1 and T2. A study was carried out to evaluate effects of images calculated in T1 and T2 obtained at 0.5T. This preliminary study concerns 28 prostate examinations with spin-echo acquisition and inversion-recuperation parameters, and provided images calculated in T1, weighted and calculated in T2. Images allowed detection and characterization of prostate lesions. However, although calculated images accentuate discrimination of the method, the weighted images conserve their place because of their improved spatial resolution.

  2. Preliminary Single-Center Canadian Experience of Human Normothermic Ex Vivo Liver Perfusion: Results of a Clinical Trial.

    Science.gov (United States)

    Bral, M; Gala-Lopez, B; Bigam, D; Kneteman, N; Malcolm, A; Livingstone, S; Andres, A; Emamaullee, J; Russell, L; Coussios, C; West, L J; Friend, P J; Shapiro, A M J

    2017-04-01

    After extensive experimentation, outcomes of a first clinical normothermic machine perfusion (NMP) liver trial in the United Kingdom demonstrated feasibility and clear safety, with improved liver function compared with standard static cold storage (SCS). We present a preliminary single-center North American experience using identical NMP technology. Ten donor liver grafts were procured, four (40%) from donation after circulatory death (DCD), of which nine were transplanted. One liver did not proceed because of a technical failure with portal cannulation and was discarded. Transplanted NMP grafts were matched 1:3 with transplanted SCS livers. Median NMP was 11.5 h (range 3.3-22.5 h) with one DCD liver perfused for 22.5 h. All transplanted livers functioned, and serum transaminases, bilirubin, international normalized ratio, and lactate levels corrected in NMP recipients similarly to controls. Graft survival at 30 days (primary outcome) was not statistically different between groups on an intent-to-treat basis (p = 0.25). Intensive care and hospital stays were significantly more prolonged in the NMP group. This preliminary experience demonstrates feasibility as well as potential technical risks of NMP in a North American setting and highlights a need for larger, randomized studies. © 2016 The American Society of Transplantation and the American Society of Transplant Surgeons.

  3. Public preferences for establishing nephrology facilities in Greenland: estimating willingness-to-pay using a discrete choice experiment.

    Science.gov (United States)

    Kjær, Trine; Bech, Mickael; Kronborg, Christian; Mørkbak, Morten Raun

    2013-10-01

    At present there are no nephrology facilities in Greenland. Greenlandic patients with renal failure needing dialysis thus have to travel to Denmark to obtain treatment. For patients in haemodialysis this necessitates a permanent residence in Denmark. Our study was aimed at examining Greenlanders' preferences for establishing nephrology facilities in Greenland at Queen Ingrid's Hospital in Nuuk, and to estimate the associated change in welfare. Preferences were elicited using a discrete choice experiment (DCE). A random sample of 500 individuals of the general population was sent a postal questionnaire in which they were asked to consider the trade-offs of establishing nephrology facilities in Greenland as opposed to the current situation. This involved trading off the benefits of having such facilities in their home country against the costs of the intervention. Besides including a payment attribute described in terms of incremental tax payment, the DCE included two interventions attributes related to (1) the organisation of labour, and (2) the physical settings of the patients. Respondents succeeded in answering the DCE despite cultural and linguistic disparity. We found that all the included attributes had a significant effect on respondents' choices, and that respondents' answers to the DCE were in keeping with their values as stated in the questionnaire. DCE data was analyzed using a random parameter logit model reparametrized in willingness-to-pay space. The results showed that establishing facilities in Greenland were preferred to the current treatment in Denmark. The welfare estimate from the DCE, at DKK 18.74 million, exceeds the estimated annual costs of establishing treatment facilities for patients with chronic renal failure. Given the estimated confidence interval this result seems robust. Establishing facilities in Greenland therefore would appear to be welfare-improving, deriving positive net benefits. Despite the relatively narrow policy focus, we

  4. The Dysarthria Impact Profile: A Preliminary French Experience with Parkinson’s Disease

    Directory of Open Access Journals (Sweden)

    Alban Letanneux

    2013-01-01

    Full Text Available This preliminary study aimed to adapt the Dysarthria Impact Profile (DIP in French and to confirm its relevance for the assessment of the psychosocial impact of dysarthria in Parkinson's disease (PD. The DIP scale was administered to 10 people with PD and 10 age-matched control subjects. The DIP psychometric properties were calculated (discriminant validity, internal consistency, and concurrent validity, notably by using the Voice Handicap Index (VHI for interscale comparisons. The French version of the DIP discriminated people with PD from control subjects (χ2 test, P<0.05. Good internal consistency was observed in both populations (Cronbach’s α=0.93 for PD people and α=0.76 for control subjects. The DIP was highly correlated with the VHI (Spearman’s ρ=-0.70, P<0.01, confirming the external validity of the scale. There was no direct relationship between PD speech and quality of life as assessed by the Parkinson’s Disease Questionnaire-39 (PDQ-39. Our preliminary data suggest that the French version of the DIP has the potential to make a useful contribution for the assessment and outcome management in acquired dysarthria for both clinicians and researchers.

  5. A preliminary investigation of the environmental Control and Life Support Subsystems (EC/LSS) for animal and plant experiment payloads

    Science.gov (United States)

    Wells, H. B.

    1972-01-01

    A preliminary study of the environmental control and life support subsystems (EC/LSS) necessary for an earth orbital spacecraft to conduct biological experiments is presented. The primary spacecraft models available for conducting these biological experiments are the space shuttle and modular space station. The experiments would be housed in a separate module that would be contained in either the shuttle payload bay or attached to the modular space station. This module would be manned only for experiment-related tasks, and would contain a separate EC/LSS for the crew and animals. Metabolic data were tabulated on various animals that are considered useful for a typical experiment program. The minimum payload for the 30-day space shuttle module was found to require about the equivalent of a one-man EC/LSS; however, the selected two-man shuttle assemblies will give a growth and contingency factor of about 50 percent. The maximum payloads for the space station mission will require at least a seven-man EC/LSS for the laboratory colony and a nine-man EC/LSS for the centrifuge colony. There is practically no room for growth or contingencies in these areas.

  6. Frictional sliding in layered rock: Preliminary experiments on stacked Lexan plates

    Energy Technology Data Exchange (ETDEWEB)

    Perry, K.E. Jr.; Epstein, J.S. [Idaho National Engineering Laboratory, Idaho Falls, ID (United States). Fracture Behavior Group; Jung, J. [Sandia National Labs., Albuquerque, NM (United States)

    1995-12-31

    Understanding the mechanical behavior of jointed-rock masses is of critical importance to designing and predicting the performance of a potential nuclear waste repositiry. To this end we have studied the frictional sliding between simulated rock joints using phase shifting moire interferometry. Preliminary calibration models were made from stacks of Lexan plates that were sand-blasted to provide a uniform frictional interface. Load was applied monotonically and phase shifted moire fringe patterns were recorded at three different load states. Plots of slip along the interfaces for the model are presented to demonstrate the ability of the photomechanics technique to provide precise measurements of in-plane displacement, and ultimately the slip between the plates.

  7. Preliminary Experience with a New Multidirectional Videoendoscope for Neuroendoscopic Surgical Procedures.

    Directory of Open Access Journals (Sweden)

    Luigi Maria Cavallo

    Full Text Available We assessed the applicability of a new multidirectional videoendoscope (digiCAMeleon, Karl Storz GmbH, Tuttlingen, Germany in various neuroendoscopic procedures.A 4-mm-diameter rigid videoendoscope (digiCAMeleon, Karl Storz GmbH, Tuttlingen, Germany with 1 sensor and an internal LED light source was tested. The device offers a resolution of 1920 x 1080 pixels and weighs ≈ 215 g. The prototype was tested on three cadaveric heads using three different approaches: a endoscopic endonasal transsphenoidal; b frontal transcortical intraventricular; c supraorbital.We identified several major benefits of the integrated system as applied to endoscopic endonasal, transcortical intraventricular, and endoscopic supraorbital keyhole approaches. These included improved maneuverability of the scope on account of reduced bulk and integration of the camera and fiberoptic light components, a variable angle of view from 0-70 degrees, and a novel feature that can be activated to maintain orientation of the surgical horizon. Our preliminary report highlights the potential for handling the videoendoscope in one hand, as one would a microsurgical instrument. The videoendoscope harbors all its electronic and lighting data into a unique and thin cable, thus resembling a modern "all-in-one" computer technology. Because of its reduced weight and ergonomic shape, controlling its movements is very easy and comfortable, even in the microsurgical environment. Furthermore, the videoendoscope offers the unique feature of orienting the horizon of vision, thanks to the possibility of offering angled views while working; this helps the surgeons to stay oriented with direct visualization and improved control of the instruments over a specific area of interest.The videoendoscope prototype represents an HD-image quality versatile tool in a neurosurgical environment, thanks to its reduced weight and dimensions; in these preliminary simulations, we have identified optimized visibility

  8. Preliminary Experience with a New Multidirectional Videoendoscope for Neuroendoscopic Surgical Procedures

    Science.gov (United States)

    Cavallo, Luigi Maria; Di Somma, Alberto; Solari, Domenico; de Divitiis, Oreste; Bracale, Umberto Marcello; Cappabianca, Paolo

    2016-01-01

    Purpose We assessed the applicability of a new multidirectional videoendoscope (digiCAMeleon, Karl Storz GmbH, Tuttlingen, Germany) in various neuroendoscopic procedures. Methods A 4-mm-diameter rigid videoendoscope (digiCAMeleon, Karl Storz GmbH, Tuttlingen, Germany) with 1 sensor and an internal LED light source was tested. The device offers a resolution of 1920 x 1080 pixels and weighs ≈ 215 g. The prototype was tested on three cadaveric heads using three different approaches: a) endoscopic endonasal transsphenoidal; b) frontal transcortical intraventricular; c) supraorbital. Results We identified several major benefits of the integrated system as applied to endoscopic endonasal, transcortical intraventricular, and endoscopic supraorbital keyhole approaches. These included improved maneuverability of the scope on account of reduced bulk and integration of the camera and fiberoptic light components, a variable angle of view from 0–70 degrees, and a novel feature that can be activated to maintain orientation of the surgical horizon. Our preliminary report highlights the potential for handling the videoendoscope in one hand, as one would a microsurgical instrument. The videoendoscope harbors all its electronic and lighting data into a unique and thin cable, thus resembling a modern "all-in-one" computer technology. Because of its reduced weight and ergonomic shape, controlling its movements is very easy and comfortable, even in the microsurgical environment. Furthermore, the videoendoscope offers the unique feature of orienting the horizon of vision, thanks to the possibility of offering angled views while working; this helps the surgeons to stay oriented with direct visualization and improved control of the instruments over a specific area of interest. Conclusions The videoendoscope prototype represents an HD-image quality versatile tool in a neurosurgical environment, thanks to its reduced weight and dimensions; in these preliminary simulations, we have

  9. Student Participation in Ecological Research: Preliminary Insights from Students' Experiences in the Smoky Mountains

    Science.gov (United States)

    Pacifici, Lara B.; Miller, Craig; Thomson, Norman

    2009-01-01

    Students participating in summer research internships at the Great Smoky Mountain National Park kept electronic journals to document their experiences. We used a combined content analysis to quantify the responses from the students in particular areas of interest and to understand the essence of experiences from the explanations provided in their…

  10. Near-Death Experiences and the "Fantasy-Prone" Personality: Preliminary Findings.

    Science.gov (United States)

    Council, James R.; Greyson, Bruce

    Near-death experiences (NDEs) are subjective experiences at the threshold of death which can include strong positive affect, dissociation from the physical body, and paranormal/transcendental phenomena. Empirical investigation of NDEs has typically relied upon retrospective reports and personality studies of individuals who have come close to…

  11. Preliminary study of tolerance of ambiguity of individuals reporting paranormal experiences.

    Science.gov (United States)

    Houran, J

    1998-02-01

    This research tested the notion that poltergeist-like experiences reflect the need to explain anomalous personal experiences. Thus, it was hypothesized that percipients of poltergeists would score lower on tolerance of ambiguity than controls. Further, it was hypothesized that tolerance of ambiguity would negatively correlate with the number of different categories of poltergeist experience. 30 self-identified percipients of poltergeist-like phenomena and 30 self-identified nonpercipients of the paranormal were administered the Rydell-Rosen Ambiguity Tolerance Scale and Houran and Lange's Poltergeist Experiences Checklist. Results partially supported predictions. Percipients of the paranormal scored significantly lower on tolerance of ambiguity than nonpercipients, but scores on the experiences checklist did not significantly correlate with scores on tolerance of ambiguity. The results supported the main hypothesis but more detailed research is needed to clarify the roles of age and tolerance of ambiguity in the perception of anomalous phenomena.

  12. Gender and urban infrastructural poverty experience in Africa: A preliminary survey in Ibadan city, Nigeria

    Directory of Open Access Journals (Sweden)

    Raimi. A. Asiyanbola

    2012-12-01

    Full Text Available The paper examines gender differences in the urban infrastructural poverty experience in an African city – Ibadan, Nigeria. The result of the cross-sectional survey of 232 households sampled in Ibadan city shows that there is intra-urban variation in the women and men urban infrastructure experience in Ibadan. The result of the correlation analysis shows that there is significant relationship between women and men urban infrastructure experience and the household income, educational level, household size and the stage in the life cycle; only with the urban infrastructure experience of the women is a significant relationship found with the occupation and the responsibility in the household. The result of the multiple linear regression analysis shows that the impact/effect of the socio-cultural, demographic and economic characteristics are more on women experience of urban infrastructure than on men’s experience. While the relative contributions of the economic characteristics, family characteristics and socio-cultural characteristics in that order are all significant in explaining the variance in women’s experience of urban infrastructure, only economic characteristics and family characteristics in that order are found to be significant in the case of the men. Also, the most important socio-cultural demographic and economic variables as shown by the beta coefficients for women are household income, household size, and responsibility in the household, while for men are the household income and the household size. Policy implications of the findings are highlighted in the paper.

  13. Preliminary experiment design of graphite dust emission measurement under accident conditions for HTGR

    Energy Technology Data Exchange (ETDEWEB)

    Peng, Wei, E-mail: pengwei@tsinghua.edu.cn [Institute of Nuclear and New Energy Technology of Tsinghua University, Advanced Nuclear Energy Technology Cooperation Innovation Center, The Key Laboratory of Advanced Nuclear Engineering and Safety, Ministry of Education, Beijing 100084 (China); Chen, Tao; Sun, Qi; Wang, Jie [Institute of Nuclear and New Energy Technology of Tsinghua University, Advanced Nuclear Energy Technology Cooperation Innovation Center, The Key Laboratory of Advanced Nuclear Engineering and Safety, Ministry of Education, Beijing 100084 (China); Yu, Suyuan, E-mail: suyuan@tsinghua.edu.cn [Center for Combustion Energy, The Key Laboratory for Thermal Science and Power Engineering, Ministry of Education, Tsinghua University, Beijing 100084 (China)

    2017-05-15

    Highlights: • A theoretical analysis is used to predict the total graphite dust release for an AVR LOCA. • Similarity criteria must be satisfied between the experiment and the actual HTGR system. • Model experiments should be conducted to predict the graphite dust resuspension rate. - Abstract: The graphite dust movement behavior is significant for the safety analyses of high-temperature gas cooled reactor (HTGR). The graphite dust release for accident conditions is an important source term for HTGR safety analyses. Depressurization release tests are not practical in HTGR because of a radioactivity release to the environment. Thus, a theoretical analysis and similarity principles were used to design a group of modeling experiments. Modeling experiments for fan start-up and depressurization process and actual experiments of helium circulator start-up in an HTGR were used to predict the rate of graphite dust resuspension and the graphite dust concentration, which can be used to predict the graphite dust release during accidents. The modeling experiments are easy to realize and the helium circulator start-up test does not harm the reactor system or the environment, so this experiment program is easily achieved. The revised Rock’n’Roll model was then used to calculate the AVR reactor release. The calculation results indicate that the total graphite dust releases during a LOCA will be about 0.65 g in AVR.

  14. Study to perform preliminary experiments to evaluate particle generation and characterization techniques for zero-gravity cloud physics experiments

    Science.gov (United States)

    Katz, U.

    1982-01-01

    Methods of particle generation and characterization with regard to their applicability for experiments requiring cloud condensation nuclei (CCN) of specified properties were investigated. Since aerosol characterization is a prerequisite to assessing performance of particle generation equipment, techniques for characterizing aerosol were evaluated. Aerosol generation is discussed, and atomizer and photolytic generators including preparation of hydrosols (used with atomizers) and the evaluation of a flight version of an atomizer are studied.

  15. Preliminary design of laser-induced breakdown spectroscopy for proto-Material Plasma Exposure eXperiment.

    Science.gov (United States)

    Shaw, G; Martin, M Z; Martin, R; Biewer, T M

    2014-11-01

    Laser-induced breakdown spectroscopy (LIBS) is a technique for measuring surface matter composition. LIBS is performed by focusing laser radiation onto a target surface, ablating the surface, forming a plasma, and analyzing the light produced. LIBS surface analysis is a possible diagnostic for characterizing plasma-facing materials in ITER. Oak Ridge National Laboratory has enabled the initial installation of a laser-induced breakdown spectroscopy diagnostic on the prototype Material-Plasma Exposure eXperiment (Proto-MPEX), which strives to mimic the conditions found at the surface of the ITER divertor. This paper will discuss the LIBS implementation on Proto-MPEX, preliminary design of the fiber optic LIBS collection probe, and the expected results.

  16. The Thirty Gigahertz Instrument Receiver for the QUIJOTE Experiment: Preliminary Polarization Measurements and Systematic-Error Analysis

    Science.gov (United States)

    Casas, Francisco J.; Ortiz, David; Villa, Enrique; Cano, Juan L.; Cagigas, Jaime; Pérez, Ana R.; Aja, Beatriz; Terán, J. Vicente; de la Fuente, Luisa; Artal, Eduardo; Hoyland, Roger; Génova-Santos, Ricardo

    2015-01-01

    This paper presents preliminary polarization measurements and systematic-error characterization of the Thirty Gigahertz Instrument receiver developed for the QUIJOTE experiment. The instrument has been designed to measure the polarization of Cosmic Microwave Background radiation from the sky, obtaining the Q, U, and I Stokes parameters of the incoming signal simultaneously. Two kinds of linearly polarized input signals have been used as excitations in the polarimeter measurement tests in the laboratory; these show consistent results in terms of the Stokes parameters obtained. A measurement-based systematic-error characterization technique has been used in order to determine the possible sources of instrumental errors and to assist in the polarimeter calibration process. PMID:26251906

  17. The Thirty Gigahertz Instrument Receiver for the QUIJOTE Experiment: Preliminary Polarization Measurements and Systematic-Error Analysis

    Directory of Open Access Journals (Sweden)

    Francisco J. Casas

    2015-08-01

    Full Text Available This paper presents preliminary polarization measurements and systematic-error characterization of the Thirty Gigahertz Instrument receiver developed for the QUIJOTE experiment. The instrument has been designed to measure the polarization of Cosmic Microwave Background radiation from the sky, obtaining the Q, U, and I Stokes parameters of the incoming signal simultaneously. Two kinds of linearly polarized input signals have been used as excitations in the polarimeter measurement tests in the laboratory; these show consistent results in terms of the Stokes parameters obtained. A measurement-based systematic-error characterization technique has been used in order to determine the possible sources of instrumental errors and to assist in the polarimeter calibration process.

  18. Potential flow calculations and preliminary wing design in support of an NLF variable sweep transition flight experiment

    Science.gov (United States)

    Waggoner, E. G.; Phillips, P. S.; Viken, J. K.; Davis, W. H.

    1985-01-01

    NASA Langley and NASA Ames-Dryden have defined a variable-sweep transition-flight experiment utilizing the F-14 aircraft to enhance understanding of the interaction of crossflow and Tollmien-Schlichting instabilities on a laminar-boundary-layer transition. The F-14 wing outer panel will be modified to generate favorable pressure gradients on the upper wing surface over a wide range of flight conditions. Extensive computations have been performed using two-dimensional and three-dimensional transonic analysis codes. Flight-test and computational data are compared and shown to validate the applicability of the three-dimensional codes (WBPPW and TAWFIVE). In addition, results from two preliminary glove designs derived from two different approaches to the design problem are presented. Advantages and disadvantages of each approach are identified, and it is concluded that coupling an analysis code with an automated design procedure yields a powerful code with distinct advantages over a 'cut-and-dry' approach.

  19. [Preliminary research on application of Q method in studying experiences of Chinese medicine famous veteran doctors].

    Science.gov (United States)

    Liu, Meng-Yu; Peng, Jin; Jiang, Miao

    2010-10-01

    As the stands, one-sidedness of subjective understanding and subjective bias is surely existed in the study of Chinese medicine (CM) doctors' experiences, so to find appropriate methods for inheriting the real experiences of experts is needed. Since CM thinking presents as a system integral way of intention thinking and a mental process of subject, to study CM experts' experiences in virtue of Q method, a psychological research method for the subjective sense, must be feasible. The application of Q method was inspected in this article, it was considered to be capable of sorting the experts, integrating the opinions of experts and comparing their opinions from multi-pointviews. A test investigation was carried out by applying Q method to analyze the CM measures, getting from some chosen gynecology specialists, for regain pregnancy in women underwent spontaneous abortion, for exploring the applicative value of Q method in the co-cognizance formation of experts' experiences.

  20. Preliminary study of religious, spiritual and mystical experiences. Thematic analysis of Poles adult’s narratives

    Directory of Open Access Journals (Sweden)

    Marta Magdalena Boczkowska

    2016-07-01

    Full Text Available The aim of this study was to examine narratives of the personal religious, spiritual and mystical experiences of adult Poles (N = 74 and their impact on narrative identity. The method for collecting qualitative data about individual understandings and spiritual, religious and mystical experiences was the narrative interview, developed on the basis of the Life Story Interview. During the analysis, the following key topics were identified: awareness of the presence/protection of God, a peak experience, the awareness of oneness with nature and the world, and a sense of closeness/contact with a person who has died. This study provides specific information on the spiritual, religious and mystical experiences of the investigated group of Poles.

  1. Preliminary Results from the GPS-Reflections Mediterranean Balloon Experiment (GPSR MEBEX)

    Science.gov (United States)

    Garrison, James L.; Ruffini, Giulio; Rius, Antonio; Cardellach, Estelle; Masters, Dallas; Armathys, Michael; Zavorotny, Valery

    2000-01-01

    An experiment to collect bistatically scattered GPS signals from a balloon at 37 km altitude has been conducted. This experiment represented the highest altitude to date that such signals were successfully recorded. The flight took place in August 1999 over the Mediterranean sea, between a launch in Sicily and recovery near Nerpio, a town in the Sierra de Segura, Albacete province of Huelva, Spain. Results from this experiment are presented, showing the waveform shape as compared to theoretical calculations. These results will be used to validate analytical models which form the basis of wind vector retrieval algorithms. These algorithms are already being validated from aircraft altitudes, but may be applied to data from future spaceborne GPS receivers. Surface wind data from radiosondes were used for comparison. This experiment was a cooperative project between NASA, the IEEC in Barcelona, and the University of Colorado at Boulder.

  2. Preliminary Results from the GPS-Reflections Mediterranean Balloon Experiment (GPSR-MEBEX)

    Science.gov (United States)

    Garrison, James L.; Ruffini, Giulio; Rius, Antonio; Cardellach, Estelle; Masters, Dallas; Armatys, Michael; Zavorotny, Valery; Bauer, Frank H. (Technical Monitor)

    2000-01-01

    An experiment to collect bistatically scattered GPS signals from a balloon at 37 km altitude has been conducted. This experiment represented the highest altitude to date that such signals were successfully recorded. The flight took place in August 1999 over the Mediterranean sea, between a launch in Sicily and recovery near Nerpio, a town in the Sierra de Segura, Albacete province of Huelva, Spain. Results from this experiment are presented, showing the waveform shape as compared to theoretical calculations. These results will be used to validate analytical models which form the basis of wind vector retrieval algorithms. These algorithms are already being validated from aircraft altitudes, but may be applied to data from future spacebourne GPS receivers. Surface wind data from radiosondes were used for comparison. This experiment was a cooperative project between NASA, the IEEC in Barcelona, and the University of Colorado at Boulder.

  3. Blastocyst transfer for patients with multiple assisted reproduction treatment failures: preliminary experience.

    Science.gov (United States)

    Sakkas, D; Percival, G; D'Arcy, Y; Lenton, W; Sharif, K; Afnan, M

    2001-01-01

    This preliminary study reports the results obtained from a patient group in which blastocyst culture and transfer were performed, and discusses the advantages and disadvantages of introducing blastocyst transfer in a clinic. Twenty-six patients who had failed to achieve a pregnancy in previous in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) treatments were offered the choice of a fresh cycle with culture to the blastocyst stage. Of the 26 patients who elected to attempt blastocyst culture, 11 opted to have transfer on day 2 or day 3 due to low numbers of embryos. Of the 15 patients who proceeded to blastocyst culture, 46.2% of the embryos cultured reached the blastocyst stage or later and eight of the patients achieved a clinical pregnancy. More oocytes were collected in this patient group, hence the chances of obtaining blastocysts were higher. Offering blastocyst culture to patients with a reasonable chance of success who have had previous multiple assisted reproduction failures is an acceptable way of introducing blastocyst culture into practice.

  4. Outcome measures to evaluate new technology for tonsillectomy: preliminary experience with Coblation

    Science.gov (United States)

    Shah, Udayan K.; Puchalski, Robert; Briggs, Marianne; Chiavacci, Rosetta; Galinkin, Jeffrey

    2001-05-01

    Evaluating the benefits of new surgical technologies does not end with the observation of successful instrument-to- tissue interaction. The impact of new technologies in medicine today is also gauged by improvements in patients' daily activities and performance. We present our outcomes assessment tool for judging the value of applying a novel tonsillectomy technique, plasma- mediated ablation using Coblation technology. Plasma- mediated ablation (PMA) achieves soft tissue resection in the oropharynx by energizing protons to break bonds. Less heat is released, allowing for less thermal injury, and possibly less pain, than with tonsillectomy performed using electrocautery alone. Children undergoing tonsillectomy by PMA, were evaluated using our outcomes-based scale, which asked families to report the degree of interruption of normal activities for the patient and their family during the post-tonsillectomy recovery period. A preliminary review of several outcomes assessments exemplify the benefits and limitations of this tool. The tracking of valuable data is weighed against the limitations of a short time course relative to the duration of disability, and a poor response rate. Future work aims to improve this data collection tool to allow application to other new technologies in otolaryngology.

  5. Estimation of desmosponge (Porifera, Demospongiae) larval settlement rates from short-term recruitment rates: Preliminary experiments

    Science.gov (United States)

    Zea, Sven

    1992-09-01

    During a study of the spatial and temporal patterns of desmosponge (Porifera, Demospongiae) recruitment on rocky and coral reef habitats of Santa Marta, Colombian Caribbean Sea, preliminary attempts were made to estimate actual settlement rates from short-term (1 to a few days) recruitment censuses. Short-term recruitment rates on black, acrylic plastic plates attached to open, non-cryptic substratum by anchor screws were low and variable (0 5 recruits/plate in 1 2 days, sets of n=5 10 plates), but reflected the depth and seasonal trends found using mid-term (1 to a few months) censusing intervals. Moreover, mortality of recruits during 1 2 day intervals was low (0 12%). Thus, short-term censusing intervals can be used to estimate actual settlement rates. To be able to make statistical comparisons, however, it is necessary to increase the number of recruits per census by pooling data of n plates per set, and to have more than one set per site or treatment.

  6. Establishment and preliminary application of Dengue virus envelope domain Ⅲ IgG antibody capture enzyme-linked immuno-absorbent assay

    Institute of Scientific and Technical Information of China (English)

    胡冬梅

    2013-01-01

    Objective To establish a highly sensitive and specific assay to detect Dengue virus(DENV) envelope protein domainⅢ(EDⅢ) IgG antibody,and to explore its value in the diagnosis and seroepidemiological survey of dengue

  7. Acquisition procedures, processing methodologies and preliminary results of magnetic and ROV data collected during the TOMO-ETNA experiment

    Directory of Open Access Journals (Sweden)

    Danilo Cavallaro

    2016-09-01

    Full Text Available The TOMO-ETNA experiment was devised for the investigation of the continental and oceanic crust beneath Mt. Etna volcano and northeastern Sicily up to the Aeolian Islands, through an active source study. In this experiment, a large amount of geophysical data was collected both inland and in the Ionian and Tyrrhenian Seas for identifying the major geological and structural features offshore Mt. Etna and NE Sicily. One of the oceanographic cruises organized within the TOMO-ETNA experiment was carried out on the hydrographic vessel “Galatea” by Italian Navy. During the cruise a detailed magnetic survey and a set of ROV (remotely operated vehicle dives were performed offshore Mt. Etna. The magnetic survey allowed the compilation of a preliminary magnetic map revealing a clear direct relationship between volcanic structures and high frequency magnetic anomalies. Significant positive magnetic anomalies were identified offshore the Timpa area and along the easternmost portion of the Riposto Ridge and correlated to a primitive volcanic edifice and to shallow volcanic bodies, respectively. On the whole, the magnetic anomaly map highlights a clear SW-NE decreasing trend, where high amplitude positive magnetic anomaly pattern of the SW sector passes, northeastwardly, to a main negative one. ROV dives permitted to directly explore the shallowest sectors of the Riposto Ridge and to collect several videos and seafloor samples, allowing us to identify some locally developed volcanic manifestations.

  8. Preliminary studies for the ORganics Exposure in Orbit (OREOcube) Experiment on the International Space Station

    Science.gov (United States)

    Alonzo, Jason; Fresneau, A.; Elsaesser, A.; Chan, J.; Breitenbach, A.; Ehrenfreund, P.; Ricco, A.; Salama, F.; Mattioda, A.; Santos, O.; Cottin, H.; Dartois, E.; d'Hendecourt, L.; Demets, R.; Foing, B.; Martins, Z.; Sephton, M.; Spaans, M.; Quinn, R.

    2013-01-01

    Organic compounds that survive in uncommon space environments are an important astrobiology focus. The ORganics Exposure in Orbit (OREOcube) experiment will investigate, in real time, chemical changes in organic compounds exposed to low Earth orbit radiation conditions on an International Space Station (ISS) external platform. OREOcube is packaged as an identical pair of 10-cm cube instruments, each weighing electronics, microcontroller, and data storage to make each cube an autonomous stand-alone instrument package requiring only a standard power and data interface. We have characterized the influence of mineralogically relevant inorganic materials on the stability, modification, and degradation of the organic molecules under ground laboratory experimental conditions. The results of our laboratory experiments will be used as the basis for the selection of samples for further investigations on the OREOcube ISS experiment. OREOcube is an international collaboration between the European Space Agency, the National Aeronautics and Space Administration, and University partners.

  9. Student Satisfaction or Happiness?: A Preliminary Rethink of What Is Important in the Student Experience

    Science.gov (United States)

    Dean, Aftab; Gibbs, Paul

    2015-01-01

    Purpose: This paper aims to investigate the purpose of the complex open system of higher education and to explore this transformative experience as personal flourishing, where students come to terms with a way of being, matching their potentiality with their agency and leading to profound happiness. There is influential, but not uncontested…

  10. Experience Sampling of Positive Affect in Adolescents with Autism: Feasibility and Preliminary Findings.

    Science.gov (United States)

    Kovac, Megan; Mosner, Maya; Miller, Stephanie; Hanna, Eleanor K; Dichter, Gabriel S

    2016-01-01

    Experience sampling is a powerful method for obtaining ecologically valid data from research participants in real-world contexts. Given the urgent need for innovative and sensitive outcome measures in autism spectrum disorder (ASD) research, the present study sought to examine the feasibility of using experience sampling of positive affect and behavior in adolescents with ASD. Nineteen high functioning adolescents with ASD and 20 sex and age matched controls completed smartphone- and Qualtrics® -based experience sampling of positive affect and behavior six times over four days. Adherence was excellent: adolescents with ASD completed 85% of the assessments, compared to 93% in controls, and response rates were not impacted by age or IQ. Groups did not differ in positive affect overall or as a function of activities, nor did groups differ in the proportion of assessments completed during social or nonsocial activities. However, groups did differ in the proportion of assessments completed during preferred activities. Results suggest that smartphone- and Qualtrics® -based experience sampling with high functioning adolescents with ASD is feasible and captures real-world behaviors that would not be possible using laboratory-based measures.

  11. Preliminary analysis of the MER magnetic properties experiment using a computational fluid dynamics model

    DEFF Research Database (Denmark)

    Kinch, K.M.; Merrison, J.P.; Gunnlaugsson, H.P.;

    2006-01-01

    Motivated by questions raised by the magnetic properties experiments on the NASA Mars Pathfinder and Mars Exploration Rover (MER) missions, we have studied in detail the capture of airborne magnetic dust by permanent magnets using a computational fluid dynamics (CFD) model supported by laboratory...

  12. A Preliminary Theoretical Analysis of a Research Experience for Undergraduates Community Model

    Science.gov (United States)

    Castillo-Garsow, Carlos; Castillo-Chavez, Carlos; Woodley, Sherry

    2013-01-01

    The Mathematical and Theoretical Biology Institute (MTBI) is a successful summer research experience for undergraduates, with a strong record of mentoring Ph.D. graduates, particularly, underrepresented minority students. However, the MTBI program was designed for education in research, not for research in education, and the mechanisms of the…

  13. Preliminary Explorations of Indigenous Perspectives of Educational Management: The Evolving Malaysian Experience.

    Science.gov (United States)

    Bajunid, Ibrahim Ahmad

    1996-01-01

    Articulates the need to understand and seek indigenous perspectives of educational management, using Malaysia's experience as an example. To differentiate culture-free and culture-bound content in educational management, the field's core corpus of theories, concepts, and terminology must be identified; the culture-specific ways of knowing must be…

  14. Student Satisfaction or Happiness?: A Preliminary Rethink of What Is Important in the Student Experience

    Science.gov (United States)

    Dean, Aftab; Gibbs, Paul

    2015-01-01

    Purpose: This paper aims to investigate the purpose of the complex open system of higher education and to explore this transformative experience as personal flourishing, where students come to terms with a way of being, matching their potentiality with their agency and leading to profound happiness. There is influential, but not uncontested…

  15. Preliminary studies for the ORganics Exposure in Orbit (OREOcube) Experiment on the International Space Station

    NARCIS (Netherlands)

    Alonzo, Jason; Fresneau, A.; Elsaesser, A.; Chan, J.; Breitenbach, A.; Ehrenfreund, P.; Ricco, A.; Salama, F.; Mattioda, A.; Santos, O.; Cottin, H.; Dartois, E.; d'Hendecourt, L.; Demets, R.; Foing, B.; Martins, Z.; Sephton, M.; Spaans, M.; Quinn, R.

    2013-01-01

    Organic compounds that survive in uncommon space environments are an important astrobiology focus. The ORganics Exposure in Orbit (OREOcube) experiment will investigate, in real time, chemical changes in organic compounds exposed to low Earth orbit radiation conditions on an International Space Stat

  16. Preliminary studies for the ORganics Exposure in Orbit (OREOcube) Experiment on the International Space Station

    NARCIS (Netherlands)

    Alonzo, Jason; Fresneau, A.; Elsaesser, A.; Chan, J.; Breitenbach, A.; Ehrenfreund, P.; Ricco, A.; Salama, F.; Mattioda, A.; Santos, O.; Cottin, H.; Dartois, E.; d'Hendecourt, L.; Demets, R.; Foing, B.; Martins, Z.; Sephton, M.; Spaans, M.; Quinn, R.

    Organic compounds that survive in uncommon space environments are animportant astrobiology focus. The ORganics Exposure in Orbit (OREOcube)experiment will investigate, in real time, chemical changes in organiccompounds exposed to low Earth orbit radiation conditions on anInternational Space Station

  17. Silent game as Model for Examining Student Online Creativity - Preliminary Results from an Experiment

    DEFF Research Database (Denmark)

    Sørensen, Jannick Kirk

    the creative dialogues developed through a very constrained communicative environment. The participants could only communicate their creative ideas by placing standard LEGO bricks on a plate. No talking or any other communication was allowed. The game used in the experiment is an adoption of the so...

  18. Preliminary studies for the ORganics Exposure in Orbit (OREOcube) Experiment on the International Space Station

    NARCIS (Netherlands)

    Alonzo, Jason; Fresneau, A.; Elsaesser, A.; Chan, J.; Breitenbach, A.; Ehrenfreund, P.; Ricco, A.; Salama, F.; Mattioda, A.; Santos, O.; Cottin, H.; Dartois, E.; d'Hendecourt, L.; Demets, R.; Foing, B.; Martins, Z.; Sephton, M.; Spaans, M.; Quinn, R.

    2013-01-01

    Organic compounds that survive in uncommon space environments are animportant astrobiology focus. The ORganics Exposure in Orbit (OREOcube)experiment will investigate, in real time, chemical changes in organiccompounds exposed to low Earth orbit radiation conditions on anInternational Space Station

  19. Preliminary studies for the ORganics Exposure in Orbit (OREOcube) Experiment on the International Space Station

    NARCIS (Netherlands)

    Alonzo, Jason; Fresneau, A.; Elsaesser, A.; Chan, J.; Breitenbach, A.; Ehrenfreund, P.; Ricco, A.; Salama, F.; Mattioda, A.; Santos, O.; Cottin, H.; Dartois, E.; d'Hendecourt, L.; Demets, R.; Foing, B.; Martins, Z.; Sephton, M.; Spaans, M.; Quinn, R.

    2013-01-01

    Organic compounds that survive in uncommon space environments are an important astrobiology focus. The ORganics Exposure in Orbit (OREOcube) experiment will investigate, in real time, chemical changes in organic compounds exposed to low Earth orbit radiation conditions on an International Space Stat

  20. Characterize Behaviour of Emerging Pollutants in Artificial Recharge: Column Experiments - Experiment Design and Results of Preliminary Tests

    Science.gov (United States)

    Wang, H.; Carrera, J.; Ayora, C.; Licha, T.

    2012-04-01

    Emerging pollutants (EPs) have been detected in water resources as a result of human activities in recent years. They include pharmaceuticals, personal care products, dioxins, flame retardants, etc. They are a source of concern because many of them are resistant to conventional water treatment, and they are harmful to human health, even in low concentrations. Generally, this study aims to characterize the behaviour of emerging pollutants in reclaimed water in column experiments which simulates artificial recharge. One column set includes three parts: influent, reactive layer column (RLC) and aquifer column (AC). The main influent is decided to be Secondary Effluent (SE) of El Prat Wastewater Treatment Plant, Barcelona. The flow rate of the column experiment is 0.9-1.5 mL/min. the residence time of RLC is designed to be about 1 day and 30-40 days for AC. Both columns are made of stainless steel. Reactive layer column (DI 10cm * L55cm) is named after the filling material which is a mixture of organic substrate, clay and goethite. One purpose of the application of the mixture is to increase dissolve organic carbon (DOC). Leaching test in batchs and columns has been done to select proper organic substrate. As a result, compost was selected due to its long lasting of releasing organic matter (OM). The other purpose of the application of the mixture is to enhance adsorption of EPs. Partition coefficients (Kow) of EPs indicate the ability of adsorption to OM. EPs with logKow>2 could be adsorbed to OM, like Ibuprofen, Bezafibrate and Diclofenac. Moreover, some of EPs are charged in the solution with pH=7, according to its acid dissociation constant (Ka). Positively charged EPs, for example Atenolol, could adsorb to clay. In the opposite, negatively charged EPs, for example Gemfibrozil, could adsorb to goethite. Aquifer column (DI 35cm * L1.5m) is to simulate the processes taking place in aquifer in artificial recharge. The filling of AC has two parts: silica sand and

  1. Preliminary Findings of the Photovoltaic Cell Calibration Experiment on Pathfinder Flight 95-3

    Science.gov (United States)

    Vargas-Aburto, Carlos

    1997-01-01

    The objective of the photovoltaic (PV) cell calibration experiment for Pathfinder was to develop an experiment compatible with an ultralight UAV to predict the performance of PV cells at AM0, the solar spectrum in space, using the Langley plot technique. The Langley plot is a valuable technique for this purpose and requires accurate measurements of air mass (pressure), cell temperature, solar irradiance, and current-voltage(IV) characteristics with the cells directed normal to the direct ray of the sun. Pathfinder's mission objective (95-3) of 65,000 ft. maximum altitude, is ideal for performing the Langley plot measurements. Miniaturization of electronic data acquisition equipment enabled the design and construction of an accurate and light weight measurement system that meets Pathfinder's low payload weight requirements.

  2. Zero-gravity cloud physics laboratory: Candidate experiments definition and preliminary concept studies

    Science.gov (United States)

    Eaton, L. R.; Greco, R. V.; Hollinden, A. B.

    1973-01-01

    The candidate definition studies on the zero-g cloud physics laboratory are covered. This laboratory will be an independent self-contained shuttle sortie payload. Several critical technology areas have been identified and studied to assure proper consideration in terms of engineering requirements for the final design. Areas include chambers, gas and particle generators, environmental controls, motion controls, change controls, observational techniques, and composition controls. This unique laboratory will allow studies to be performed without mechanical, aerodynamics, electrical, or other type techniques to support the object under study. This report also covers the candidate experiment definitions, chambers and experiment classes, laboratory concepts and plans, special supporting studies, early flight opportunities and payload planning data for overall shuttle payload requirements assessments.

  3. Preliminary study of feasibility of an experiment looking for excited state double beta transitions in Tin

    CERN Document Server

    Das, Soumik; Raina, P K; Singh, A K; Rath, P K; Cappella, F; Cerulli, R; Laubenstein, M; Belli, P; Bernabei, R

    2015-01-01

    A first attempt to study the feasibility of an experiment to search for double beta decay in $^{124}$Sn and $^{112}$Sn was carried out by using ultra-low background HPGe detector (244 cm$^{3}$) inside the Gran Sasso National Laboratory (LNGS) of the INFN (Italy). A small sample of natural Sn was examined for 2367.5 h. The radioactive contamination of the sample has been estimated. The data has also been considered to calculate the present sensitivity for the proposed search; half-life limits $\\sim$ $10^{17} - 10^{18}$ years for $\\beta^{+}$EC and EC-EC processes in $^{112}$Sn and $\\sim$ $10^{18}$ years for $\\beta^{-}\\beta^{-}$ transition in $^{124}$Sn were measured. In the last section of the paper the enhancement of the sensitivity for a proposed experiment with larger mass to reach theoretically estimated values of half-lives is discussed.

  4. Video-assisted anal fistula treatment: technical considerations and preliminary results of the first brazilian experience

    OpenAIRE

    Mendes,Carlos Ramon Silveira; FERREIRA, Luciano Santana de Miranda; Sapucaia,Ricardo Aguiar; LIMA, Meyline Andrade; Araujo, Sergio Eduardo Alonso

    2014-01-01

    Backgroung : Anorectal fistula represents an epithelized communication path of infectious origin between the rectum or anal canal and the perianal region. The association of endoscopic surgery with the minimally invasive approach led to the development of the video-assisted anal fistula treatment. Aim : To describe the technique and initial experience with the technique video-assisted for anal fistula treatment. Technique : A Karl Storz video equipment was used. Main steps included the ...

  5. 试论企业信息优势与竞争优势的建立%Preliminary Discussion on Establishing Information Advantages and Competitive Advantages in Enterprises

    Institute of Scientific and Technical Information of China (English)

    徐欣娅

    2003-01-01

    The paper first explains the necessity and importance for enterprises to establish information advantages and competitive advantages, and then gives a detailed description of ERP, competitive archives for enterprises, special-ized intelligence, diversion from information advantages to competitive advantages and so on.

  6. Post-irradiation Examination of the AGR-1 Experiment: Plans and Preliminary Results

    Energy Technology Data Exchange (ETDEWEB)

    Paul Demkowicz

    2001-10-01

    Abstract – The AGR-1 irradiation experiment contains seventy-two individual cylindrical fuel compacts (25 mm long x 12.5 mm diameter) each containing approximately 4100 TRISO-coated uranium oxycarbide fuel particles. The experiment accumulated 620 effective full power days in the Advanced Test Reactor at the Idaho National Laboratory with peak burnups exceeding 19% FIMA. An extensive post-irradiation examination campaign will be performed on the AGR-1 fuel in order to characterize the irradiated fuel properties, assess the in-pile fuel performance in terms of coating integrity and fission metals release, and determine the fission product retention behavior during high temperature accident testing. PIE experiments will include dimensional measurements of fuel and irradiated graphite, burnup measurements, assessment of fission metals release during irradiation, evaluation of coating integrity using the leach-burn-leach technique, microscopic examination of kernel and coating microstructures, and accident testing of the fuel in helium at temperatures up to 1800°C. Activities completed to date include opening of the irradiated capsules, measurement of fuel dimensions, and gamma spectrometry of selected fuel compacts.

  7. Preliminary study of kaonic deuterium X-rays by the SIDDHARTA experiment at DAΦNE

    Energy Technology Data Exchange (ETDEWEB)

    Bazzi, M. [INFN, Laboratori Nazionali di Frascati, C.P. 13, Via E. Fermi 40, I-00044 Frascati (Roma) (Italy); Beer, G. [Department of Physics and Astronomy, University of Victoria, P.O. Box 3055, Victoria BC V8W3P6 (Canada); Berucci, C. [Stefan-Meyer-Institut für subatomare Physik, Boltzmanngasse 3, 1090 Wien (Austria); INFN, Laboratori Nazionali di Frascati, C.P. 13, Via E. Fermi 40, I-00044 Frascati (Roma) (Italy); Bombelli, L. [Politecnico di Milano, Dipartimento di Elettronica e Informazione, Piazza L. da Vinci 32, I-20133 Milano (Italy); Bragadireanu, A.M. [INFN, Laboratori Nazionali di Frascati, C.P. 13, Via E. Fermi 40, I-00044 Frascati (Roma) (Italy); IFIN-HH, Institutul National pentru Fizica si Inginerie Nucleara Horia Hulubei, Reactorului 30, Magurele (Romania); Cargnelli, M., E-mail: michael.cargnelli@oaaw.ac.at [Stefan-Meyer-Institut für subatomare Physik, Boltzmanngasse 3, 1090 Wien (Austria); Curceanu, C.; D' Uffizi, A. [INFN, Laboratori Nazionali di Frascati, C.P. 13, Via E. Fermi 40, I-00044 Frascati (Roma) (Italy); Fiorini, C.; Frizzi, T. [Politecnico di Milano, Dipartimento di Elettronica e Informazione, Piazza L. da Vinci 32, I-20133 Milano (Italy); Ghio, F. [INFN Sezione di Roma I and Instituto Superiore di Sanita, I-00161 Roma (Italy); Guaraldo, C. [INFN, Laboratori Nazionali di Frascati, C.P. 13, Via E. Fermi 40, I-00044 Frascati (Roma) (Italy); Hayano, R. [University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo (Japan); Iliescu, M. [INFN, Laboratori Nazionali di Frascati, C.P. 13, Via E. Fermi 40, I-00044 Frascati (Roma) (Italy); Ishiwatari, T. [Stefan-Meyer-Institut für subatomare Physik, Boltzmanngasse 3, 1090 Wien (Austria); Iwasaki, M. [RIKEN, Institute of Physical and Chemical Research, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); and others

    2013-06-03

    The study of the K{sup ¯}N system at very low energies plays a key role for the understanding of the strong interaction between hadrons in the strangeness sector. At the DAΦNE electron–positron collider of Laboratori Nazionali di Frascati we studied kaonic atoms with Z=1 and Z=2, taking advantage of the low-energy charged kaons from Φ-mesons decaying nearly at rest. The SIDDHARTA experiment used X-ray spectroscopy of the kaonic atoms to determine the transition yields and the strong interaction induced shift and width of the lowest experimentally accessible level (1s for H and D and 2p for He). Shift and width are connected to the real and imaginary part of the scattering length. To disentangle the isospin dependent scattering lengths of the antikaon–nucleon interaction, measurements of K{sup −}p and of K{sup −}d are needed. We report here on an exploratory deuterium measurement, from which a limit for the yield of the K-series transitions was derived: Y(K{sub tot})<0.0143 and Y(K{sub α})<0.0039 (CL 90%). Also, the upcoming SIDDHARTA-2 kaonic deuterium experiment is introduced.

  8. Preliminary study of kaonic deuterium X-rays by the SIDDHARTA experiment at DAΦNE.

    Science.gov (United States)

    Bazzi, M; Beer, G; Berucci, C; Bombelli, L; Bragadireanu, A M; Cargnelli, M; Curceanu Petrascu, C; Dʼuffizi, A; Fiorini, C; Frizzi, T; Ghio, F; Guaraldo, C; Hayano, R; Iliescu, M; Ishiwatari, T; Iwasaki, M; Kienle, P; Levi Sandri, P; Longoni, A; Marton, J; Okada, S; Pietreanu, D; Ponta, T; Romero Vidal, A; Sbardella, E; Scordo, A; Shi, H; Sirghi, D L; Sirghi, F; Tatsuno, H; Tudorache, A; Tudorache, V; Vazquez Doce, O; Widmann, E; Zmeskal, J

    2013-06-03

    The study of the [Formula: see text] system at very low energies plays a key role for the understanding of the strong interaction between hadrons in the strangeness sector. At the DAΦNE electron-positron collider of Laboratori Nazionali di Frascati we studied kaonic atoms with [Formula: see text] and [Formula: see text], taking advantage of the low-energy charged kaons from Φ-mesons decaying nearly at rest. The SIDDHARTA experiment used X-ray spectroscopy of the kaonic atoms to determine the transition yields and the strong interaction induced shift and width of the lowest experimentally accessible level (1s for H and D and 2p for He). Shift and width are connected to the real and imaginary part of the scattering length. To disentangle the isospin dependent scattering lengths of the antikaon-nucleon interaction, measurements of [Formula: see text] and of [Formula: see text] are needed. We report here on an exploratory deuterium measurement, from which a limit for the yield of the K-series transitions was derived: [Formula: see text] and [Formula: see text] (CL 90%). Also, the upcoming SIDDHARTA-2 kaonic deuterium experiment is introduced.

  9. Preliminary investigation of relations between young students' self-regulatory strategies and their metacognitive experiences.

    Science.gov (United States)

    Dermitzaki, Irini

    2005-12-01

    The present study investigated second-graders' self-regulative behav ior during task engagement and its relations to performance and to students' on-line metacognitive experiences. Participants were 25 individually examined Greek second graders (13 boys and 12 girls; M age: 7.6 yr., SD = 0.2). Students' use of cognitive, metacognitive, and motivational regulatory strategies while performing a cognitive task were directly observed and recorded by two independent observers. Students' task-specific performance was also evaluated. Finally, students' feeling of satisfaction with the solution produced, their estimate of effort expenditure, and estimate of the solution's correctness were assessed. Analysis showed these second grade students' use of self-regulatory strategies and feeling of satisfaction were significantly associated with their performance. However, metacognitive experiences reported after the solution were only slightly related to the students' actual self-regulative behavior during the task, implying that the relations of students' regulatory efforts with their metacognitive processes are still developing at such a young age.

  10. Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience

    NARCIS (Netherlands)

    De Sousa, Paul A.; Steeg, Rachel; Wachter, Elisabeth; Bruce, Kevin; King, Jason; Hoeve, Marieke; Khadun, Shalinee; McConnachie, George; Holder, Julie; Kurtz, Andreas; Seltmann, Stefanie; Dewender, Johannes; Reimann, Sascha; Stacey, Glyn; O'Shea, Orla; Chapman, Charlotte; Healy, Lyn; Zimmermann, Heiko; Bolton, Bryan; Rawat, Trisha; Atkin, Isobel; Veiga, Anna; Kuebler, Bernd; Serano, Blanca Miranda; Saric, Tomo; Hescheler, Jürgen; Brüstle, Oliver; Peitz, Michael; Thiele, Cornelia; Geijsen, Niels; Holst, Bjørn; Clausen, Christian; Lako, Majlinda; Armstrong, Lyle; Gupta, Shailesh K.; Kvist, Alexander J.; Hicks, Ryan; Jonebring, Anna; Brolén, Gabriella; Ebneth, Andreas; Cabrera-Socorro, Alfredo; Foerch, Patrik; Geraerts, Martine; Stummann, Tina C.; Harmon, Shawn; George, Carol; Streeter, Ian; Clarke, Laura; Parkinson, Helen; Harrison, Peter W.; Faulconbridge, Adam; Cherubin, Luca; Burdett, Tony; Trigueros, Cesar; Patel, Minal J.; Lucas, Christa; Hardy, Barry; Predan, Rok; Dokler, Joh; Brajnik, Maja; Keminer, Oliver; Pless, Ole; Gribbon, Philip; Claussen, Carsten; Ringwald, Annette; Kreisel, Beate; Courtney, Aidan; Allsopp, Timothy E.

    2017-01-01

    A fast track “Hot Start” process was implemented to launch the European Bank for Induced Pluripotent Stem Cells (EBiSC) to provide early release of a range of established control and disease linked human induced pluripotent stem cell (hiPSC) lines. Established practice amongst consortium members was

  11. Predictive models applied to groundwater level forecasting: a preliminary experience on the alluvial aquifer of the Magra River (Italy).

    Science.gov (United States)

    Brozzo, Gianpiero; Doveri, Marco; Lelli, Matteo; Scozzari, Andrea

    2010-05-01

    Computer-based decision support systems are getting a growing interest for water managing authorities and water distribution companies. This work discusses a preliminary experience in the application of computational intelligence in a hydrological modeling framework, regarding the study area of the alluvial aquifer of the Magra River (Italy). Two sites in the studied area, corresponding to two distinct groups of wells (Battifollo and Fornola) are managed by the local drinkable water distribution company (ACAM Acque), which serves the area of La Spezia, on the Ligurian coast. Battifollo has 9 wells with a total extraction rate of about 240 liters per second, while Fornola has 44 wells with an extraction rate of about 900 liters per second. Objective of this work is to make use of time series coming from long-term monitoring activities in order to assess the trend of the groundwater level with respect to a set of environmental and exploitation parameters; this is accomplished by the experimentation of a suitable model, eligible to be used as a predictor. This activity moves on from the modeling of the system behavior, based on a set of Input/Output data, in order to characterize it without necessarily a prior knowledge of any deterministic mechanism (system identification). In this context, data series collected by continuous hydrological monitoring instrumentation installed in the studied sites, together with meteorological and water extraction data, have been analyzed in order to assess the applicability and performance of a predictive model of the groundwater level. A mixed approach (both data driven and process-based) has been experimented on the whole dataset relating to the last ten years of continuous monitoring activity. The system identification approach presented here is based on the integration of an adaptive technique based on Artificial Neural Networks (ANNs) and a blind deterministic identification approach. According to this concept, the behavior of

  12. 阿月浑子快速建园技术研究初报%Preliminary Study on the Rapid Establishing Orchard Technique of Pistachio (Pistacia vera)

    Institute of Scientific and Technical Information of China (English)

    马凯; 王继勋; 卢春生; 王斐; 郝庆; 闫鹏; 张平; 何健

    2012-01-01

    以阿月浑子种子为试材,研究不同层积处理时间对种子发芽的影响,探讨阿月浑子直播、小营养钵移栽、大营养袋移栽3种建园方式对苗木生长及嫁接成园的影响,提出适合于南疆地区的阿月浑子快速建园方式和技术操作要点.结果表明,阿月浑子种子层积40 d的发芽率可达90%以上,延长层积时间能够促进未开裂种子开裂发芽.3种建园方式中,直播建园具有操作简便、建园成本低等优点.同时直播建园和小营养钵移栽建园方式的苗木成活率、嫁接成苗率都较大营养袋移栽建园方式更高.以阿月浑子快速建园为目标,实际生产中以直播建园为主,配合小营养钵移栽补苗的方式为最佳建园方式.%Using pistachio seeds as the experimental materials, the effects of different stratification time on seed germination were studied and the influence of three orchard establishing methods direct seeding, small nutrition pot transplanting and large nutrition pot transplanting on seedling growth and grafting were investigated, then the methods and major technologies of rapid establishing pistachio orchard which was suitable for the area of southern Xinjiang was developed. The results showed that pistachio seed germination rate reached more than 90% when stratification time reached 40 days, prolonged stratification time can stimulate the non-split seeds splitting and germinating. In three methods of establishing orchard, direct seeding showed advantages of simple operation, low cost in orchard establishment. Meanwhile, the seedling survival rate, grafted seedling rate of direct seeding and small nutrition pot transplanting were higher than large nutrition pot transplanting. As a goal of rapid establishing orchard of pistachio, in actual production, direct seeding primarily, coordinate small nutrition pot transplanting was the best recommendation.

  13. Aespoe Pillar Stability Experiment. Final coupled 3D thermo-mechanical modeling. Preliminary particle mechanical modeling

    Energy Technology Data Exchange (ETDEWEB)

    Wanne, Toivo; Johansson, Erik; Potyondy, David [Saanio and Riekkola Oy, Helsinki (Finland)

    2004-02-01

    SKB is planning to perform a large-scale pillar stability experiment called APSE (Aespoe Pillar Stability Experiment) at Aespoe HRL. The study is focused on understanding and control of progressive rock failure in hard crystalline rock and damage caused by high stresses. The elastic thermo-mechanical modeling was carried out in three dimensions because of the complex test geometry and in-situ stress tensor by using a finite-difference modeling software FLAC3D. Cracking and damage formation were modeled in the area of interest (pillar between two large scale holes) in two dimensions by using the Particle Flow Code (PFC), which is based on particle mechanics. FLAC and PFC were coupled to minimize the computer resources and the computing time. According to the modeling the initial temperature rises from 15 deg C to about 65 deg C in the pillar area during the heating period of 120 days. The rising temperature due to thermal expansion induces stresses in the pillar area and after 120 days heating the stresses have increased about 33% from the excavation induced maximum stress of 150 MPa to 200 MPa in the end of the heating period. The results from FLAC3D model showed that only regions where the crack initiation stress has exceeded were identified and they extended to about two meters down the hole wall. These could be considered the areas where damage may occur during the in-situ test. When the other hole is pressurized with a 0.8 MPa confining pressure it yields that 5 MPa more stress is needed to damage the rock than without confining pressure. This makes the damaged area in some degree smaller. High compressive stresses in addition to some tensile stresses might induce some AE (acoustic emission) activity in the upper part of the hole from the very beginning of the test and are thus potential areas where AE activities may be detected. Monitoring like acoustic emissions will be measured during the test execution. The 2D coupled PFC-FLAC modeling indicated that

  14. E-Commerce Experiences in the Real Estate Industry: a preliminary study in regional Queensland

    Directory of Open Access Journals (Sweden)

    Jeanette Van Akkeren

    2003-05-01

    Full Text Available Computer systems have become commonplace in most SMEs and technology is increasingly becoming a part of doing business. In recent years, the Internet has become readily available to businesses; consequently there has been growing pressure on SMEs to take up e-commerce. However, e-commerce is perceived by many as being unproven in terms of business benefit. This research aims to determine what, if any, benefits are derived from assimilating e-commerce technologies into SME business processes. This paper presents three in-depth case studies from the Real Estate industry in a regional setting. Overall, findings were positive and identified the following experiences: enhanced business efficiencies, cost benefits, improved customer interactions and increased business return on investment.

  15. Purification, crystallization and preliminary X-ray diffraction experiment of nattokinase from Bacillus subtilis natto.

    Science.gov (United States)

    Yanagisawa, Yasuhide; Chatake, Toshiyuki; Chiba-Kamoshida, Kaori; Naito, Sawa; Ohsugi, Tadanori; Sumi, Hiroyuki; Yasuda, Ichiro; Morimoto, Yukio

    2010-12-01

    Nattokinase is a single polypeptide chain composed of 275 amino acids (molecular weight 27,724) which displays strong fibrinolytic activity. Moreover, it can activate other fibrinolytic enzymes such as pro-urokinase and tissue plasminogen activator. In the present study, native nattokinase from Bacillus subtilis natto was purified using gel-filtration chromatography and crystallized to give needle-like crystals which could be used for X-ray diffraction experiments. The crystals belonged to space group C2, with unit-cell parameters a=74.3, b=49.9, c=56.3 Å, β=95.2°. Diffraction images were processed to a resolution of 1.74 Å with an Rmerge of 5.2% (15.3% in the highest resolution shell) and a completeness of 69.8% (30.0% in the highest resolution shell). This study reports the first X-ray diffraction analysis of nattokinase.

  16. Preliminary results of the Artemia salina experiments in biostack on LDEF

    Science.gov (United States)

    Graul, E. H.; Ruether, W.; Hiendl, C. O.

    1992-01-01

    The mosaic egg of the brine shrimp, Artemia salina, resting in blastula or gastrula state represents a system that during further development, proceeds without any further development to the larval stage, the free swimming nauplius. Therefore, injury to a single cell of the egg will be manifest in the larvae. In several experiments, it was shown that the passage of a single heavy ion through the shrimp egg damaged a cellular area large enough to disturb either embryogenesis or further development of the larvae, or the integrity of the adult individual. Emergence from the egg shell was heavily disturbed by the heavy ions as was hatching. Additional late effects, due to a hit by a heavy ion, are delayed of growth and of sexual maturity, and reduced fertility. Anomalies in the body and the extremities could be observed more frequently for the nauplii which had developed from eggs hit by heavy ions.

  17. Hoe Creek II field experiment on underground coal gasification, preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Aiman, W.R.; Thorsness, C.B.; Hill, R.W.; Rozsa, R.B.; Cena, R.; Gregg, D.W.; Stephens, D.R.

    1978-02-27

    A second in-situ coal gasification experiment was performed by Lawrence Livermore Laboratory at Hoe Creek in Wyoming. The Linked Vertical Wells scheme for in-situ coal gasification was used. The experiment took 100 days for air flow testing, reverse combustion linking, forward combustion gasification, and post-burn steam flow. Air was used for gasification except for a 2-day test with oxygen and steam. Reverse combustion linking took 14 days at 1.6 m/day. Air requirements for linking were 0.398 Mgmol per meter of link assuming a single direct link. The coal pyrolysed during linking was 17 m/sup 3/, which corresponds to a single link 1.0 m in diameter. There was, however, strong evidence of at least two linkage paths. The detected links stayed below the 3 m level in the 7.6 coal seam; however, the product flow from the forward-burn gasification probably followed the coal-overburden interface not the reverse burn channels at the 3 m level. A total of 232 Mgmols (194 Mscf) of gas was produced with heating value above 125 kJ/mol (140 Btu/scf) for significant time periods and an average of 96 kJ/mol (108 Btu/scf). During the oxygen-steam test the heating value was above 270 kJ/gmol (300 Btu/scf) twice and averaged 235 kJ/gmol (265 Btu/scf). The coal recovery was 1310 m/sup 3/ (1950 ton). Gasification was terminated because of decreasing product quality not because of burn through. The product quality decreased because of increasing underground heat loss.

  18. Development of a lower extremity wearable exoskeleton with double compact elastic module: preliminary experiments

    Directory of Open Access Journals (Sweden)

    Y. Long

    2017-08-01

    Full Text Available In this paper, a double compact elastic module is designed and implemented in the lower extremity exoskeleton. The double compact elastic module is composed of two parts, i.e., physical human robot interaction (pHRI measurement and the elastic actuation system (EAS, which are called proximal elastic module (PEM and distal elastic module (DEM respectively. The PEM is used as the pHRI information collection device while the DEM is used as the compliance device. A novel compact parallelogram-like structure based torsional spring is designed and developed. An iterative finite element analysis (FEA based optimization process was conducted to find the optimal parameters in the search space. In the PEM, the designed torsional spring has an outer circle with a diameter of 60 mm and an inner hole with a diameter of 12 mm, while in the DEM, the torsional spring has the outer circle with a diameter of 80 mm and the inner circle with a diameter of 16 mm. The torsional spring in the PEM has a thickness of 5 mm and a weight of 60 g, while that in the DEM has a thickness of 10 mm and a weight of 80 g. The double compact elastic module prototype is embedded in the mechanical joint directly. Calibration experiments were conducted on those two elastic modules to obtain the linear torque versus angle characteristic. The calibration experimental results show that this torsional spring in the PEM has a stiffness of 60.2 Nm rad−1, which is capable of withstanding a maximum torque of 4 Nm, while that in the DEM has a stiffness of 80.2 Nm rad−1, which is capable of withstanding a maximum torque of 30 Nm. The experimental results and the simulation data show that the maximum resultant errors are 6 % for the PEM and 4 % for the DEM respectively. In this paper, an assumed regression algorithm is used to learn the human motion intent (HMI based on the pHRI collection. The HMI is defined as the angular position of the human limb joint. A

  19. Flexible robotic retrograde renoscopy: description of novel robotic device and preliminary laboratory experience.

    Science.gov (United States)

    Desai, Mihir M; Aron, Monish; Gill, Inderbir S; Pascal-Haber, Georges; Ukimura, Osamu; Kaouk, Jihad H; Stahler, Gregory; Barbagli, Federico; Carlson, Christopher; Moll, Fredric

    2008-07-01

    To describe a novel flexible robotic system for performing retrograde intrarenal surgery. Remote robotic flexible ureterorenoscopy was performed bilaterally in 5 acute swine (10 kidneys). A novel 14F robotic catheter system, which manipulated a passive optical fiberscope mounted on a remote catheter manipulator was used. The technical feasibility, efficiency, and reproducibility of accessing all calices were assessed. Additionally, laser lithotripsy of calculi and laser ablation of renal papillae were performed. The robotic catheter system could be introduced de novo in eight ureters; two ureters required balloon dilation. The ureteroscope could be successfully manipulated remotely into 83 (98%) of the 85 calices. The time required to inspect all calices within a given kidney decreased with experience from 15 minutes in the first kidney to 49 seconds in the last (mean 4.6 minutes). On a visual analog scale (1, worst to 10, best), the reproducibility of caliceal access was rated at 8, and instrument tip stability was rated at 10. A renal pelvic perforation constituted the solitary complication. Histologic examination of the ureter showed changes consistent with acute dilation without areas of necrosis. A novel robotic catheter system is described for performing retrograde ureterorenoscopy. The potential advantages compared with conventional manual flexible ureterorenoscopy include an increased range of motion, instrument stability, and improved ergonomics. Ongoing refinement is likely to expand the role of this technology in retrograde intrarenal surgery in the near future.

  20. Preliminary results from recent experiments and future roadmap to Shock Ignition of Fusion Targets

    Science.gov (United States)

    Batani, D.; Malka, G.; Schurtz, G.; Ribeyre, X.; Lebel, E.; Giuffrida, L.; Tikhonchuk, V.; Volpe, L.; Patria, A.; Koester, P.; Labate, L.; Gizzi, L. A.; Antonelli, L.; Richetta, M.; Nejdl, J.; Sawicka, M.; Margarone, D.; Krus, M.; Krousky, E.; Skala, J.; Dudzak, R.; Velyhan, A.; Ullshmied, J.; Renner, O.; Smid, M.; Klimo, O.; Atzeni, S.; Marocchino, A.; Schiavi, A.; Spindloe, C.; O'Dell, T.; Vinci, T.; Wolowski, J.; Badziak, J.; Pysarcizck, T.; Rosinski, M.; Kalinowska, Z.; Chodukowski, T.

    2012-11-01

    Shock ignition (SI) is a new approach to Inertial Confinement Fusion (ICF) based on decoupling the compression and ignition phase. The last one relies on launching a strong shock through a high intensity laser spike (<= 1016 W/cm2) at the end of compression. In this paper, first we described an experiment performed using the PALS iodine laser to study laser-target coupling and laser-plasma interaction in an intensity regime relevant for SI. A first beam with wavelength λ = 1.33 μm and low intensity was used to create an extended preformed plasma, and a second one with λ = 0.44 μm to create a strong shock. Several diagnostics characterized the preformed plasma and the interaction of the main pulse. Pressure up to 90 Mbar was inferred. In the last paper of the paper, we discuss the relevant steps, which can be followed in order to approach the demonstration of SI on laser facilities like LMJ.

  1. Investigation of Freeze-Linings in Copper-Containing Slag Systems: Part I. Preliminary Experiments

    Science.gov (United States)

    Fallah-Mehrjardi, Ata; Hayes, Peter C.; Jak, Evgueni

    2013-06-01

    Slag freeze-linings are increasingly used in industrial pyrometallurgical processes to insure that furnace integrity is maintained in aggressive high-temperature environments. Most previous studies of freeze-linings have analyzed the formation of slag deposits based solely on heat-transfer models. The focus of the present research is to determine the impact of slag chemistry and local process conditions on the microstructures, thickness, stability, and heat-transfer characteristics of the frozen deposit at steady-state conditions. The formation of the freeze-linings is studied under controlled laboratory conditions using an air-cooled "cold-finger" technique for Cu-Fe-Si-Al-O slag at equilibrium with metallic copper relevant to the industrial copper smelting processes. The phase assemblages and microstructures of the deposits formed in the cold-finger experiments differ significantly from those expected from phase equilibrium considerations. The freeze-lining deposits have been found, in general, to consist of several layers. Starting from the cold finger, these layers consist of glass; glass with microcrystalline precipitates; closed crystalline layer; and open crystalline layer. Even at steady-state conditions, there was no primary phase sealing layer of delafossite [Cu2O · (Al, Fe)2O3] present at the deposit/liquid interface—these observations differ markedly from those expected from phase equilibrium considerations. The findings have significant practical implications, and potential for the improved design and operation of industrial metallurgical furnaces.

  2. Preliminary experience with extraperitoneal endoscopic radical prostatectomy through duplication of the open technique

    Directory of Open Access Journals (Sweden)

    M. Tobias-Machado

    2005-06-01

    Full Text Available OBJECTIVE: To describe surgical and functional results with extraperitoneal laparoscopic radical prostatectomy with duplication of the open technique, from the experience obtained in the treatment of 28 initial cases. MATERIALS AND METHODS: In a 36-month period, we prospectively analyzed 28 patients diagnosed with localized prostate cancer undergoing extraperitoneal laparoscopic radical prostatectomy. RESULTS: Mean surgical time was 280 min, with mean blood loss of 320 mL. As intraoperative complications, there were 2 rectal lesions repaired with laparoscopic suture in 2 planes. There was no conversion to open surgery. Median hospital stay was 3 days, with return to oral diet in the first post-operative day in patients. As post-operative complications, there were 3 cases of extraperitoneal urinary fistula. Two of these cases were resolved by maintaining a Foley catheter for 21 days, and the other one by late endoscopic reintervention for repositioning the catheter. Five out of 18 previously potent patients evolved with erectile dysfunction. The diagnosis of prostate cancer was confirmed in all patients, with focal positive margin occurring in 3 cases. During a mean follow-up of 18 months, 2 patients presented increased PSA, with no clinical evidence of disease. CONCLUSION: Laparoscopic radical prostatectomy is a laborious and difficult procedure, with a long learning curve. Extraperitoneal access is feasible, and it is possible to practically duplicate the principles of open surgery. The present technique can possibly offer advantages in terms of decreased blood loss, preservation of erectile function and prevention of positive margins.

  3. Preliminary culture and life-cycle experiments with the benthic amphipod Ampelisca abdita

    Energy Technology Data Exchange (ETDEWEB)

    Redmond, M.S.; Jones, J.K.P. (AScI Corp., Newport, OR (United States)); Scott, K.J. (Science Applications International Corp., Narragansett, RI (United States)); Swartz, R.C. (Environmental Protection Agency, Newport, OR (United States))

    1994-08-01

    The tube-dwelling amphipod Ampelisca abdita Mills 1964 has been used extensively in acute sediment toxicity tests and has been shown to be amenable to chronic testing. Ampelisca abdita was held in the lab through several generations when fed algal food in daily static renewals, although culturing success was not consistent. Algal food consisted of one or more of the following: the flagellate Pseudoisochrysis paradoxa Sutton, and the diatoms Phaeodactylum tricornutum Bohlin and Chaetoceros calcitrans (Paulsen) Tokano. Sensitivity of cultured animals to cadmium chloride in 96-h seawater-only tests was comparable to that of field-collected animals. A life-cycle test initiated with juveniles 8 to 10 d old resulted in production of young or fertilized broods in only two of the 12 sample containers in which young were expected. Amphipods were sexually mature at approximately 20 d of age at 25 C, and young were first produced at 34 to 36 d. Short-term tests were used to quantify growth of this species in 10 to 14 d. Results from a variety of experiments indicated that there are still one or more unresolved problems with the culture and chronic testing of Ampelisca abdita. Factors such as nutrition, flow rate, light, and temperature need to be examined further.

  4. Video-assisted anal fistula treatment: technical considerations and preliminary results of the first Brazilian experience.

    Science.gov (United States)

    Mendes, Carlos Ramon Silveira; Ferreira, Luciano Santana de Miranda; Sapucaia, Ricardo Aguiar; Lima, Meyline Andrade; Araujo, Sergio Eduardo Alonso

    2014-01-01

    Anorectal fistula represents an epithelized communication path of infectious origin between the rectum or anal canal and the perianal region. The association of endoscopic surgery with the minimally invasive approach led to the development of the video-assisted anal fistula treatment. To describe the technique and initial experience with the technique video-assisted for anal fistula treatment. A Karl Storz video equipment was used. Main steps included the visualization of the fistula tract using the fistuloscope, the correct localization of the internal fistula opening under direct vision, endoscopic treatment of the fistula and closure of the internal opening which can be accomplished through firing a stapler, cutaneous-mucosal flap, or direct closure using suture. The mean distance between the anal verge and the external anal orifice was 5.5 cm. Mean operative time was 31.75 min. In all cases, the internal fistula opening could be identified after complete fistuloscopy. In all cases, internal fistula opening was closed using full-thickness suture. There were no intraoperative or postoperative complications. After a 5-month follow-up, recurrence was observed in one (12.5%) patient. Video-assisted anal fistula treatment is feasible, reproducible, and safe. It enables direct visualization of the fistula tract, internal opening and secondary paths.

  5. Preliminary Study on the Establishment of China's Sports Tourism Standard%我国体育旅游行业标准构建初步探讨*

    Institute of Scientific and Technical Information of China (English)

    宋彪

    2013-01-01

      我国体育旅游业处于迅速发展阶段,既有机遇,也面临挑战。建立我国体育旅游的标准,是严控体育旅游产品质量,规范体育旅游市场秩序,提升我国体育旅游业整体发展层次的有效手段。我国体育旅游标准的建立,要依据体育旅游本质特征,满足体育旅游相关者的整体利益,符合现阶段体育旅游业发展要求,着眼于体育产业与旅游业发展趋势。%China's sports tourism is in the stage of rapid development, facing both opportunities and challenges. Establishing sports tourism criterion helps to strictly control the product quality, standardize the market and improve the overall level of development of China's sports tourism. The establishment of sports tourism criterion should do the following aspects: the essential characteristics according to the sports tourism to meet the overall interests of the stakeholders, in line with the level of development of sports tourism, focusing on the sports industry and tourism development trend.

  6. The establishment of preliminary safety threshold values for cyanobacteria based on periodic variations in different microcystin congeners in Lake Chaohu, China.

    Science.gov (United States)

    Shang, Lixia; Feng, Muhua; Liu, Feifei; Xu, Xiangen; Ke, Fan; Chen, Xiangchao; Li, Wenchao

    2015-04-01

    As harmful cyanobacterial proliferation threatens the safety of drinking water supplies worldwide, it is essential to establish a safety threshold (ST) for cyanobacteria to control cyanobacterial density effectively in water sources. For this purpose, cyanobacterial abundance, microcystin (MC) production, and environmental parameters were monitored monthly from September 2011 to August 2012 in one drinking water source of Lake Chaohu. The cyanobacterial density ranged from 1400 to 220 000 cells per mL with the succession of two dominant species Microcystis and Dolichospermum, which was determined by water temperature and nutrient loading. The MC concentrations were correlated significantly with the cyanobacterial density and they varied between 0.28 and 8.86 μg L(-1). Therefore, the characteristics of MC cell quotas were classified according to four stages of the development of cyanobacteria, namely: recruitment, multiplication, decline and dormancy. The ST for cyanobacteria was established for different periods based on the MC cell quota and its guideline wherein three commonly monitored MC congeners (MC-LR, -RR and -YR) were considered in the present study. Its reliability was verified in the water source using the data collected between June 2013 and May 2014. The results highlighted the necessity to classify the ST-values in different periods referring to the main MC congeners rather than MC-LR, which will facilitate the management and control of toxic cyanobacterial proliferation in drinking water sources.

  7. Nitrogen Limitation Along The Kalahari Transect: Preliminary Results From A Stable Isotope Fertilization Experiment

    Science.gov (United States)

    Wang, L.; Macko, S.; D'Odorico, P.; Ries, L.

    2005-12-01

    Globally, savannas cover ~ 20% of the Earth's land area. Nutrients and soil moisture interactively control vegetation dynamics in many savannas although it is unclear how the relative importance of water and nutrient limitations (especially nitrogen) change with the mean climatic conditions. The Kalahari Transect (KT) in southern Africa traverses a dramatic aridity gradient (from ~ 200 mm to more than 1000 mm of mean annual precipitation (MAP), through the Republic of South Africa, Botswana, Namibia and Zambia), on relatively homogenous soils (deep Kalahari sands). This transect offers the ideal setting to study nutrient and vegetation dynamics without confounding soil effects. To improve the understanding of nitrogen and water controls on savanna vegetation, this study tested the hypothesis that the savannas in the Kalahari switch from conditions of water limitation in the dry areas to nutrient limitation in the wet areas. To this end, we conducted a large-scale stable isotope fertilization experiment using four study sites with different MAP. The transect included sites in Mongu, Zambia (MAP ~950mm), Pandamatenga, Ghanzi, and Tshane, Botswana with MAP ranging between 700 mm and 300 mm. The experimental design consisted of a randomized block design with four 21 m x 13 m plots at each site. Each plot was divided into four 10 m x 6 m subplots with 1 m buffer zone between each subplot. Four treatments (N addition, P addition, N+P addition and control) were randomly applied to the subplots. The experiment began during the dry season, in August, 2004, when 39g/m2 of Ca(NO3)2 (3.3g-N/ m2 ) was evenly applied to the N and N+P subplots, and 7.5g/m2 of Ca(H2PO4)2 (1.7g-P/m2) was applied to the P and N+P subplots, while the control subplots were left with no treatment. The N and N+P additions were enriched with 15N (Ca(15NO3)2 ) to a signature of 10.3 ‰. Before application, soil samples from two different layers (0cm and 50cm) outside the plots and foliar samples of the

  8. Preliminary experience using transthoracic echocardiography guiding percutaneous closure of ruptured right sinus of Valsalva aneurysm

    Institute of Scientific and Technical Information of China (English)

    LI Yue; WANG Guang-yi; WANG Zhi-feng; GUO Liang

    2011-01-01

    Background In the 21st century, minimally invasive treatment is one of the main developmental directions of medical sciences. It is well known that the echocardiography plays an important role during interventional treatments of some structural heart diseases. Because the ruptured right sinus of the Valsalva aneurysm (RRSVA) is a rare disease, there were few reports about percutaneous catheter closure of RRSVA. This study aimed to sum up our experience with transthoracic echocardiography (TTE) during percutaneous catheter closure of RRSVA.Methods Five RRSVA cases were treated with percutaneous catheter closure. The whole procedure was guided and monitored by TTE and fluoroscopy. The maximum diameter of the RRSVA was measured by TTE before and after the catheter passed through the rupture site. A duct occluder 2 mm larger than the maximum diameter was chosen. The closure effects were evaluated with TTE and fluoroscopy immediately after the occluding device was deployed. All patients were followed up by TTE for 8 to 30 months.Results Before the catheter passed through the rupture site the maximum diameter of the RRSVA measured with TTE and aortography were (7.9 ±2.1) mm and (7.8 ± 1.8) mm. After the catheter passed through the rupture site the maximum diameter measured with TTE was (11.2 ± 3.2) mm, which was significantly larger than before the procedure (P <0.05). The percutaneous catheter closure was successful in four cases and failed in one. Compared to the aortography the TTE was better at distinguishing residual shunts from aortic valve regurgitation immediately after the occluding device was deployed. There were no complications during 8 to 30 months of follow-up.Conclusion Transthoracic echocardiography can play an important role during percutaneous catheter closure of RRSVA,especially for estimating the size of the RRSVA after the catheter passes through the rupture site, and differentiating residual shunt from aortic valve regurgitation immediately

  9. Staff empowerment: a medical record department's preliminary experiences with continuous quality improvement.

    Science.gov (United States)

    Markon, E

    1992-11-01

    After observing the results of continuous quality improvement, no one would argue against its value in the workplace. However, learning to apply the concepts requires change on everyone's part, and the challenge lies in effecting this change. Not everyone will want to work in this type of environment and, if the organization is truly committed to continuous quality improvement, those individuals may have to make hard decisions as to whether the organization is the right place for them to work. Certain skills are required for staff empowerment to be successful, and training in these skills is essential. The medical record department staff learned early in this process that, although the group possessed job skills, interaction and team skills were lacking. The Development Dimensions International program helped the managers and staff identify the weaknesses of the group and provided educational tools for improvement. The changes often are so subtle, the group does not realize anything has changed. It was not until recently, when the medical record department staff was requested by administration to identify department quality improvement projects, that the group looked back at where the process started and realized how different things are today from three years ago--now staff members lead team meetings, work-groups are redesigning their job processes, and teams update the rest of the department staff on its progress at department meetings. Everyone expressed a sense of pride and accomplishment that the group had indeed responded to the challenge. The experiences of the medical record department thus far clearly support empowerment of employees.(ABSTRACT TRUNCATED AT 250 WORDS)

  10. Fetal reduction by bipolar cord coagulation in managing complicated monochorionic multiple pregnancies: preliminary experience in China

    Institute of Scientific and Technical Information of China (English)

    HE Zhi-ming; FANG Qun; YANG Yong-zhong; LUO Yan-min; CHEN Jun-hong; CHEN Yong-zhen; ZHOU Yi; CHEN Min-ling

    2010-01-01

    Background Monochorionic multiple pregnancies (MMPs) are associated with higher rates of perinatal morbidity and mortality caused by interfetal vascular anastomoses in the monochorionic placenta, which can lead to fetal health interactions. In some circumstances, selective feticide of the affected fetus is necessary to save the healthy co-twin. We evaluated the effects and safety of our initial experiences using bipolar cord coagulation for the management of complicated MMPs. Methods Using ultrasound-guided bipolar cord coagulation, we performed selective feticide on 14 complicated MMPs (5 with twin-twin transfusion syndrome, 4 with acardia, 3 with discordant structural anomalies, and 2 with severe selective intrauterine growth restriction). One patient with monochorionic triplets received the procedure twice to terminate 2 affected fetuses for different indications. Data regarding the operations, complications and neonatal outcomes were analyzed. Results Cord occlusions were successfully performed in 13/14 (93%) cases. The failure happened in an acardiac fetus and the pregnancy was terminated by induction. The included cases delivered at a mean gestational age of 35.4 weeks with a perinatal survival rate of 11/13 (85%). Three operation-related complications occurred (21%), including membrane rupture of the terminated sac (1 case), preterm labor at 28 weeks gestation (1 case), and chorioamniotic membrane separation (1 case). Amnioinfusion was indicated in 11 procedures to expand the target sacs for entering the trocar and obtaining sufficient working space. However, in all 4 cases of acardia, the acardiac sacs showed extreme oligohydramnios and could not be well expanded by infusion; thus, the trocar had to be inserted from the sac of the preserved co-twin. Conclusions The application of bipolar cord coagulation in complicated MMPs is safe and improves the prognosis. Amnioinfusion is useful in helping to expand the target sac when the working space is limited.

  11. Micromultileaf collimator-based stereotactic radiosurgery for selected arteriovenous malformations: Technique and preliminary experience

    Directory of Open Access Journals (Sweden)

    Jalali Rakesh

    2009-01-01

    Full Text Available Purpose : To report our experience of stereotactic radiosurgery (SRS in consecutively treated patients with arteriovenous malformations (AVMs. Materials and Methods : Of the 87 patients, 23 patients qualified and were treated with SRS as per predefined protocol according to AVM size, location, neurological status, prior bleeding, and the AVM score. All had Spletzer-Martin grade II/III and AVM scores < 2.5. Patients underwent SRS using micromultileaf collimators delivering multiple noncoplanar fixed fields. Doses were prescribed using the Flickinger model. Patients were followed up with magnetic resonance angiography (MRA and digitally subtracted angiography (DSA. Results : The mean nidus volume was 3.65 cc. The mean prescribed maximum dose was 22 Gy and the marginal dose was 19.24 Gy; 12 Gy normal brain volume was 8.39 cc and 12 Gy marginal volume was 5.03 cc. Mean dose to brain stem, pituitary hypothalamic axis, and optic chiasm was 2.5, 0.72, and 0.49 Gy, respectively. At a median follow-up of 22 months (range 1.5-71.2 months, 7 of 10 patients presenting with a neurological deficit showed significant improvement. All 15 patients who underwent MRA 1.5-2 years after SRS had no residual nidus yielding an MRA complete obliteration rate of 100%. Twelve patients also underwent a check DSA, which confirmed obliteration in 11 of them resulting in an accuracy of MRA of 92%. One patient after SRS had transient deterioration of motor power, which resolved completely after a short course of steroids and another had mild worsening of the hemiparesis. All patients are able to lead an active functional life. Conclusions : Careful selection of cases suitable for SRS provides optimum obliteration rates with low toxicity.

  12. Molten salt oxidation of mixed waste: Preliminary bench-scale experiments without radioactivity

    Energy Technology Data Exchange (ETDEWEB)

    Haas, P.A.; Rudolph, J.C.; Bell, J.T.

    1994-06-01

    Molten salt oxidation (MSO) is a process in which organic wastes are oxidized by sparging them with air through a bed of molten sodium carbonate (bp 851 {degrees}C) at {ge} 900{degrees}C. This process is readily applicable to the mixed waste because acidic products from Cl, S, P, etc., in the waste, along with most metals and most radionuclides, are retained within the melt as oxides or salts. Rockwell International has studied the application of MSO to various wastes, including some mixed waste. A unit used by Rockwell to study the mixed waste treatment is presently in use at Oak Ridge National Laboratory (ORNL). ORNL`s studies to date have concentrated on chemical flowsheet questions. Concerns that were studied included carbon monoxide (CO) emissions, NO{sub x}, emissions, and metal retention under a variety of conditions. Initial experiments show that CO emissions increase with increasing NaCl content in the melt, increasing temperature, and increasing airflow. Carbon monoxide content is especially high (> 2000 ppm) with high chlorine content (> 10%). Thermal NO{sub x}, emissions are relatively low ( < 5 ppm) at temperatures < 1000{degrees}C. However, most (85--100%) of the nitrogen in the feed as organic nitrate or amine was released as NO{sub x}, The metal contents of the melt and of knockout pot samples of condensed salt show high volatilities of Cs as CsCl. Average condensed salt concentrations were 60% for barium and 100% for strontium and cobalt. The cerium disappeared -- perhaps from deposition on the alumina reactor walls.

  13. Establishing a Wild, Ex Situ Population of a Critically Endangered Shade-Tolerant Rainforest Conifer: A Translocation Experiment

    OpenAIRE

    Zimmer, Heidi C.; Offord, Catherine A.; Auld, Tony D.; Baker, Patrick J.

    2016-01-01

    Translocation can reduce extinction risk by increasing population size and geographic range, and is increasingly being used in the management of rare and threatened plant species. A critical determinant of successful plant establishment is light environment. Wollemia nobilis (Wollemi pine) is a critically endangered conifer, with a wild population of 83 mature trees and a highly restricted distribution of less than 10 km2. We used under-planting to establish a population of W. nobilis in a ne...

  14. Designing assisted living technologies ‘in the wild’: preliminary experiences with cultural probe methodology

    Directory of Open Access Journals (Sweden)

    Wherton Joseph

    2012-12-01

    , limited emotional or psychological resources, life events, and acute illness. Discussions between researchers and participants about the materials collected (and sometimes about what had prevented them completing the tasks helped elicit further information relevant to assisted living technology design. The probe materials were particularly helpful when having conversations with non-English speaking participants through an interpreter. Conclusions Cultural probe methods can help build a rich picture of the lives and experiences of older people to facilitate the co-production of assisted living technologies. But their application may be constrained by the participant’s physical, mental and emotional capacity. They are most effective when used as a tool to facilitate communication and development of a deeper understanding of older people’s needs.

  15. Preliminary experience of fractionated stereotactic radiosurgery with extend system of Gamma Knife

    Directory of Open Access Journals (Sweden)

    Raj Bisht

    2016-03-01

    Full Text Available Purpose: The purpose of this study is to present multisession stereotactic radiosurgery with initial experience using custom made extend system (ES of Gamma Knife.Methods: The ES is comprised of a carbon fiber frame also called extend frame, vacuum head rest cushion, patient surveillance unit and a configurable front piece with dental impression tray. The extend frame is a rigid connection between patient's head and patient positioning system (PPS of Gamma Knife. A dental impression of patient was created and attached to the frontal piece of extend system. The treatment setup involves positioning the patient within the extend frame using patient specific headrest cushion and front piece. The reference patient’s head position was recorded through measurements of repositioning check tool (RCT apertures using a high precision digital probe before computed tomography (CT scan. The RCT measurements taken before treatment were compared with recorded reference position to ensure appropriate patient treatment position. Volumetric magnetic resonance (MR scan was co-registered with stereotactic CT scan on Leksell Gamma plan. Fused MR to CT images on Gamma Plan was utilized to delineate regions of interest and prepare a precise treatment plan. The presented study includes positional reproducibility check and dosimetric evaluation of ten patients treated with ES.Results: Forty-three fractions on ten patients with prescribed treatment format were delivered successfully. An average tumor volume of 11.26 cm3 (range, 340 mm3 to 59.12 cm3 was treated with ES. The mean tumor coverage of 91.91% (range, 90% to 95% was able to achieve at 50% prescription isodose without compromising adjacent normal structure radiation dose tolerances. The mean inter-fraction positional variation of 0.69 mm influences an inherent strength of immobilization technique. Follow-up of seven patients at a median interval of 16 months (range, 9 months to 26 months showed evidence of 100

  16. Global atmospheric response to specific linear combinations of the main SST modes.. Part I: numerical experiments and preliminary results

    Science.gov (United States)

    Trzaska, S.; Moron, V.; Fontaine, B.

    1996-10-01

    This article investigates through numerical experiments the controversial question of the impact of El Niño-Southern Oscillation (ENSO) phenomena on climate according to large-scale and regional-scale interhemispheric thermal contrast. Eight experiments (two considering only inversed Atlantic thermal anomalies and six combining ENSO warm phase with large-scale interhemispheric contrast and Atlantic anomaly patterns) were performed with the Météo-France atmospheric general circulation model. The definition of boundary conditions from observed composites and principal components is presented and preliminary results concerning the month of August, especially over West Africa and the equatorial Atlantic are discussed. Results are coherent with observations and show that interhemispheric and regional scale sea-surface-temperature anomaly (SST) patterns could significantly modulate the impact of ENSO phenomena: the impact of warm-phase ENSO, relative to the atmospheric model intercomparison project (AMIP) climatology, seems stronger when embedded in global and regional SSTA patterns representative of the post-1970 conditions [i.e. with temperatures warmer (colder) than the long-term mean in the southern hemisphere (northern hemisphere)]. Atlantic SSTAs may also play a significant role. Acknowledgements. We gratefully appreciate the on-line DMSP database facility at APL (Newell et al., 1991) from which this study has benefited greatly. We wish to thank E. Friis-Christensen for his encouragement and useful discussions. A. Y. would like to thank the Danish Meteorological Institute, where this work was done, for its hospitality during his stay there and the Nordic Baltic Scholarship Scheme for its financial support of this stay. Topical Editor K.-H. Glassmeier thanks M. J. Engebretson and H. Lühr for their help in evaluating this paper.--> Correspondence to: A. Yahnin-->

  17. CT-guided thin needles percutaneous cryoablation (PCA) in patients with primary and secondary lung tumors: A preliminary experience

    Energy Technology Data Exchange (ETDEWEB)

    Pusceddu, Claudio, E-mail: clapusceddu@gmail.com [Division of Interventional Radiology, Department of Oncological Radiology, Businco Hospital, Regional Referral Center for Oncologic Diseases, Cagliari, Zip code 09100 (Italy); Sotgia, Barbara, E-mail: barbara.sotgia@gmail.com [Department of Oncological Radiology, Businco Hospital, Regional Referral Center for Oncological Diseases, Cagliari, Zip code 09100 (Italy); Fele, Rosa Maria, E-mail: rosellafele@tiscali.it [Department of Oncological Radiology, Businco Hospital, Regional Referral Center for Oncological Diseases, Cagliari, Zip code 09100 (Italy); Melis, Luca, E-mail: doclucamelis@tiscali.it [Department of Oncological Radiology, Businco Hospital, Regional Referral Center for Oncological Diseases, Cagliari, Zip code 09100 (Italy)

    2013-05-15

    Purpose: To report the data of our initial experience with CT-guided thin cryoprobes for percutaneous cryoablation (PCA) in patients with primary and secondary pulmonary tumors. Material and methods: CT-guided thin needles PCA was performed on 34 lung masses (11 NSCLC = 32%; 23 secondary lung malignancies = 68%) in 32 consecutive patients (24 men and 8 women; mean age 67 ± 10 years) not suitable for surgical resection. Lung masses were treated using two types of cryoprobes: IceRod and IceSeed able to obtain different size of iceball. The number of probes used ranged from 1 to 5 depending on the size of the tumor. After insertion of the cryoprobes into the lesion, the PCA were performed with two 2 (91%) or 3 (9%) cycles each of 12 min of freezing followed by a 4 min active thawing phase and a 4 min passive thawing phase for each one for all treatments. Results: All cryoablation sessions were successfully completed. All primary and metastatic lung tumors were ablated. No procedure-related deaths occurred. Morbidity consisted of 21% (7 of 34) pneumothorax and 3% (1 of 34) cases asymptomatic small pulmonary hemorrhage, respectively, all of CTCAE grade 1 (Common Terminology Criteria for Adverse Events). Low density of entire lesion, central necrosis and solid mass appearance were identify in 21 (62%), 7 (21%) and 6 (17%) of cryoablated tumors, respectively. No lymphadenopathy developed in the region of treated lesions. Technical success (complete lack of enhancement) was achieved in 82%, 97% and 91% of treated lesions at 1-, 3- and 6-months CT follow-up scan, respectively (p < .000). Comparing the tumor longest diameter between the baseline and at 6 month CT images, technical success was revealed in 92% cases (p < .000). Conclusion: Our preliminary experience suggests that PCA is a feasible treatment option. Well-designed clinical trials with a larger patient population are necessary to further investigate the long-term results and prognostic factors.

  18. Establishing a Wild, Ex Situ Population of a Critically Endangered Shade-Tolerant Rainforest Conifer: A Translocation Experiment.

    Directory of Open Access Journals (Sweden)

    Heidi C Zimmer

    Full Text Available Translocation can reduce extinction risk by increasing population size and geographic range, and is increasingly being used in the management of rare and threatened plant species. A critical determinant of successful plant establishment is light environment. Wollemia nobilis (Wollemi pine is a critically endangered conifer, with a wild population of 83 mature trees and a highly restricted distribution of less than 10 km2. We used under-planting to establish a population of W. nobilis in a new rainforest site. Because its optimal establishment conditions were unknown, we conducted an experimental translocation, planting in a range of different light conditions from deeply shaded to high light gaps. Two years after the experimental translocation, 85% of plants had survived. There were two distinct responses: very high survival (94% but very low growth, and lower survival (69% and higher growth, associated with initial plant condition. Overall survival of translocated W. nobilis was strongly increased in planting sites with higher light, in contrast to previous studies demonstrating long-term survival of wild W. nobilis juveniles in deep shade. Translocation by under-planting may be useful in establishing new populations of shade-tolerant plant species, not least by utilizing the range of light conditions that occur in forest understories.

  19. Establishing a Wild, Ex Situ Population of a Critically Endangered Shade-Tolerant Rainforest Conifer: A Translocation Experiment.

    Science.gov (United States)

    Zimmer, Heidi C; Offord, Catherine A; Auld, Tony D; Baker, Patrick J

    2016-01-01

    Translocation can reduce extinction risk by increasing population size and geographic range, and is increasingly being used in the management of rare and threatened plant species. A critical determinant of successful plant establishment is light environment. Wollemia nobilis (Wollemi pine) is a critically endangered conifer, with a wild population of 83 mature trees and a highly restricted distribution of less than 10 km2. We used under-planting to establish a population of W. nobilis in a new rainforest site. Because its optimal establishment conditions were unknown, we conducted an experimental translocation, planting in a range of different light conditions from deeply shaded to high light gaps. Two years after the experimental translocation, 85% of plants had survived. There were two distinct responses: very high survival (94%) but very low growth, and lower survival (69%) and higher growth, associated with initial plant condition. Overall survival of translocated W. nobilis was strongly increased in planting sites with higher light, in contrast to previous studies demonstrating long-term survival of wild W. nobilis juveniles in deep shade. Translocation by under-planting may be useful in establishing new populations of shade-tolerant plant species, not least by utilizing the range of light conditions that occur in forest understories.

  20. Thermal energy storage in aquifiers: preliminary information

    Energy Technology Data Exchange (ETDEWEB)

    Allen, R.D.

    1979-12-01

    Topics discussed include: conceptual designs; numerical modelling; field experiments; relevant technical information; feasibility studies; preliminary aquifer selection considerations; and preliminary design and operating considerations. (TFD)

  1. Establishing of monitoring network on Kosovo Rivers: preliminary measurements on the four main rivers (Drini i Bardhë, Morava e Binqës, Lepenc and Sitnica).

    Science.gov (United States)

    Gashi, Fatbardh; Frančišković-Bilinski, Stanislav; Bilinski, Halka; Troni, Naser; Bacaj, Mustafë; Jusufi, Florim

    2011-04-01

    Morava e Binçës River and the other (S5) on Sitnica River (56 km from boarder to Serbia). Comparison with available results from the past shows that water pollution with respect to toxic elements decreased since 1989, what is explained with closing of heavy industry since then. Continuation of water and sediment monitoring using more than one experimental technique is highly recommended, particularly at locations S2 and S5 with anomalous concentrations of toxic elements, as well as establishing of permanent network of monitoring stations by Kosovo authorities. Remediation of sediments at polluted locations in Sitnica River would be desirable.

  2. Estonian Experience on Establishment of a Modern National Poison Information Centre: One-year Profile of Phone Calls in 2012

    Directory of Open Access Journals (Sweden)

    Mare Oder

    2013-06-01

    Full Text Available Background: Initiating a National Poisoning Information Centre (PIC in Estonia took about 12 years of challenging work on research, training and attracting governmental support and funding. In this study we described the establishment process and the profile of phone calls in the first year which the PIC started to be available full time (24h/day 7days/week.  Methods: This was a descriptive retrospective study. Relevant documents from 2000-2012 were reviewed. The documents were categorized into 5 main issues against establishment of PIC. Data of all inquiries related to toxic agent exposures regarding patient’s demographic, intention of poisoning and type of toxic substances in 2012 were collected. The data were reported with frequency and percentage. Results: During establishment process, 386 documents including governmental regulations and contracts, memorandums from meetings, professional e-mails, newspaper articles, interviews, annual reports and program sheets of other poison centres and conference presentations were collected. Funding was provided form PHARE and BTox projects (2000-2003, and government of Estonia (2004-2012. Educational programs were held to train specialists in clinical toxicology and poisoning information to direct the PIC. The active phase of establishment started in 2004; however, the services of PIC became available at the beginning of 2008. In 2012, total number of calls was 1118. 20% of calls were related to general questions about pharmaceuticals and non-toxic agents. 894 calls were related to acute poisoning cases. Most of them (87.9% were due to accidental poisoning. The most common types of substances responsible for poisoning were pharmaceutical products (30.2%, household products (29.5% and plant toxins (11.1%. Conclusion: To establish a stable PIC, it is crucial to have a wide range data backbone, clear support and direct funding from the government, assistance from collaborative PICs, active international

  3. Preliminary establishment and assessment of Affective Music System%情绪音乐库的初步编制与评定

    Institute of Scientific and Technical Information of China (English)

    李冬冬; 程真波; 戴瑞娜; 汪芬; 黄宇霞

    2012-01-01

    目的:建立一套适用于中国的标准化音乐刺激材料库.方法:从音乐网站、论坛等收集到预期能引起积极、中性和消极情绪的音乐l99首,请音乐专业人士及乐感较好的若干小组成员依据诱发情绪的明确性、音乐的熟悉度和声音的质量三个标准筛选出78首音乐.征集160名在校大学生,对音乐的愉悦度、唤醒度和表达性进行自我报告的9点量表评分.结果:三维度的各评分段均有一定数量音乐材料分布,中、高分段音乐数量偏多,占总数70%以上;愉悦度、唤醒度和表达性评分两两之间具有较高正相关(r=0.85 ~0.90,均P<0.01),唤醒度对表达性与愉悦度关系的调节效应显著(β=-0.17,P<0.01);在对3个维度的评分上,男生组和女生组均呈较高正相关(r =0.95 ~0.99,均P<0.01),但男生愉悦度和唤醒度评分均明显高于女生(均P<0.05);聚类分析将音乐聚为3类,分别可引发预期的积极、中性和消极三种情绪.结论:本研究初步编制了一套情绪音乐库,可作为情绪刺激材料,但仍有待扩充和更细致的评定.%Objective: To establish a set of standard music stimuli for emotional research in China. Methods: Totally 199 pieces of music that were believed to induce positive, neutral and negative emotion were collected in diverse ways, including music websites and forums. Seventy-eight pieces of them were selected for this study by music experts with emotional specificity, music familiarity and sound quality as standards. Totally 160 college students were recruited and instructed to rate these pieces of music on happiness, arousal and expression with a 9-point rating scale. Results: The scores for the different pieces of music varied widely, with middle and high scores accounting for 70% of the total ratings. The rating scores for happiness, arousal and expression were strongly positive correlated with each other (r =0. 85 -0.90, Ps <0.01). Arousal

  4. Preliminary establishment of the laboratory diagnostic test for malignant hyperthermia%恶性高热实验室诊断方法的初步建立

    Institute of Scientific and Technical Information of China (English)

    王颖林; 郭向阳; 罗爱伦; 黄宇光; 叶铁虎; 任洪智; 谭刚; 崔旭蕾

    2008-01-01

    目的 初步建立恶性高热(MH)的实验室诊断方法-咖啡因-氟烷骨骼肌收缩试验(CHCT).方法 选取10头实验小型猪和1头皮特兰猪,肌肉注射氯胺酮和地西泮麻醉后,静脉注射硫喷妥钠5mg/kg和琥珀胆碱2mg/kg麻醉诱导后气管插管,机械通气,吸入2%~3%氟烷4 h,新鲜气流量为2 L/min,纯氧和空气各1 L/min.记录麻醉过程中及麻醉结束后48 h内MH的发生情况.气管插管后即刻取耳组织,采用常规酚氯仿方法提取基因组DNA,检测蓝尼定受体-1(RYR1)基因的突变情况.根据北美MH研究组的标准建立CHCT的实验装置,气管插管后即刻取股四头肌近肌腱部位的肌纤维,进行CHCT.结果 实验小型猪均未见MH发作,而皮特兰猪在麻醉过程中出现MH的特征性表现.RYR1基因检测显示,实验小型猪均为氟烷抗性基因型(HALNN);皮特兰猪为氟烷易感基因型(HALnn).CHCT结果表明,实验小型猪诊断为非MH易感猪,皮特兰猪诊断为MH易感猪.结论 .实验小型猪和皮特兰猪的CHCT诊断结果与特征性表现及RYR1基因检测结果均一致,初步验证本实验室CHCT设备的稳定性及测定结果的可靠性.%Objective To preliminarily establish laboratory diagnostic test for malignant hyperthermia (MH) -- caffeine and halothane contracture test (CHCT). Methods Ten Chinese experimental miniature pigs (CEMP) and one pietrain swine were selected in this study. The animals were anesthetized with ketamine and diasepam. Anesthesia was induced with thiopental sodium 5 mg/kg and tracheal intubation was facilitated with suecinylcholine 2 mg/kg intravenously. The animals were mechanically ventilated and anesthesia was maintained with inhalation of 2%-3% halothane for4 h. Frash gas flow was set at 2 L/min and oxygen and air flow at 1 L/ min. All the aninals were observed whether the MH episodes were initiated or not during the process of anesthesia and 48 h after anesthesia. Ear tissues were removed immediately after

  5. Establishing a successful pre-hospital emergency service in a developing country: experience from Rescue 1122 service in Pakistan.

    Science.gov (United States)

    Waseem, Hunniya; Naseer, Rizwan; Razzak, Junaid Abdul

    2011-06-01

    As in many other developing countries, emergency medical services, especially pre-hospital emergency care, has long been neglected in Pakistan. Consequently, patients are brought to the emergency departments by relatives or bystanders in private cars, taxis or any other readily available mode of transportation. Ambulances, where they exist, have barely a stretcher and arrangements for oxygen supply. Modern emergency services are considered too costly for many countries. A model of pre-hospital emergency services, called Rescue 1122 and established in Punjab province of Pakistan, is presented. The system is supported by government funding and provides a quality service. The article describes the process of establishment of the service, the organisational structure, the scope of services and the role it is currently playing in the healthcare of the region it serves.

  6. Immediate conversion to CAS after neurological intolerance at cross-clamping test during CEA: a preliminary experience.

    Science.gov (United States)

    Guy Bianchi, P; Tolva, V; Dalainas, I; Bertoni, G; Cireni, L; Trimarchi, S; Rampoldi, V; Casana, R

    2012-02-01

    The aim of this preliminary study is to evaluate the feasibility and efficacy of CAS as treatment option to endarterectomy when carotid shunt cannot be used safely. The medical records concerning 469 carotid stenosis treated between January 2006 and December 2009 were retrospectively reviewed, focusing on cross-clamp intolerance during CEA. Patients with cross-clamping intolerance were divided in two groups. Group 1: those that concluded the open procedure with the use of a shunt, and Group 2: those who experience immediate brain intolerance and coma and were immediately converted to an endovascular procedure. Mortality and neurological adverse event rate were compared between shunted CEA and cross-clamping intolerant cases converted into CAS. The secondary end-point was long-term survival. Carotid cross-clamp intolerance occurred in 30 cases (8.7%). CEA with Pruitt-Inahara's shunt was performed in 17 cases with a perioperative neurological adverse event rate of 23.5%. In 13 cases limitations to shunting due to quick onset of coma and/or an unfavorable anatomy were encountered. In these 13 cases the open intervention was immediately converted into endovascular procedure. Technical success was achieved in all the converted to CAS cases (100%), with a perioperative neurological adverse event rate of 7.7% (P=0.35 between the two groups). No significant difference emerges comparing patient's survival between the cases Nevertheless, the small dimension of this survey, immediate conversion to CAS resulted feasible with a lower risk of neurological adverse events if compared to CEA with shunt, and could be considered as an alternative to CEA when carotid shunt cannot be used safely.

  7. Production of microspheres labeled with holmium-166 for liver cancer therapy: the preliminary experience at IPEN/CNEN-SP

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Renata F.; Azevedo, Mariangela B.M.; Nascimento, Nanci; Sene, Frank F.; Martinelli, Jose R.; Osso Junior, Joao A., E-mail: renatafcosta@usp.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2009-07-01

    Microspheres labeled with therapeutic radionuclides for malignancies of liver are widely used in many countries. The internal radionuclide therapy uses a permanently implanted device, such as Therasphere{sup R} or SIR-Spheres{sup R}, or a biodegradable device that provides structural support for the radionuclide of choice and causes the tumor reduction. Three different types of material supports have been investigated, i.e., biodegradable polymer-based, glass-based and resin-based microspheres. Nowadays there is a project concerning the labeling of these 3 materials with {sup 166}Ho being developed at IPEN-CNEN/SP and coordinated by the Radiopharmacy Directory. {sup 166}Ho(t{sub 1/2}=26.8 h) is a beta minus emitter (E{sub max}=1.84 MeV), with right properties for radiotherapy and can be produced with the low power Brazilian Nuclear Reactor IEA-R1m. The aim of this work is to describe the stage of development of this project. The initial experience used resin-based microspheres, a cation exchange resin labeled with {sup 166}Ho, it showed the essential characteristics for liver therapy. Preliminary results of the preparation of glass-based microspheres labeled with {sup 165}Ho showed that 5% of Ho{sub 2}O{sub 3} was incorporated in an aluminosilicate glass, through the process of spheronization by flame, which produced spherical microspheres with 20-40mum particle size. The preparation of biodegradable material, polymer-based microspheres, is in its initial stage and the objective is to prepare and label with {sup 165}Ho different polymer-based microspheres. These combined efforts have been done to offer a national radiotherapeutic product for the the Brazilian nuclear medicine community at fair value and also to offer a viable possibility of treatment for patients affected by liver malignancies. (author)

  8. Establishment of Provincial Unions of the Cities of Siberia: Experience of Regional Identity Construction in Wartime (1914–1916

    Directory of Open Access Journals (Sweden)

    Olga A. Kharus

    2014-09-01

    Full Text Available The article presents the approach to the detection of the role and place of provincial organizations of All-Russian Union of Cities in the social life of the Siberia, which is based on the analysis of the social practices, concerned with their establishment in the context of the regional identity construction. The paper detects the specific character of the forms and methods of Siberian identity representation, used by the liberal initiative minority in the First World War. The reasons, preventing the implementation of the project of creating of broad coalition of the public, based on the development of self-government institutions development are determined.

  9. Establishing a Space of Dialogue and Possibilities: Student Experience and Meaning at the University of the Witwatersrand

    Science.gov (United States)

    Cross, M.; Johnson, B.

    2008-01-01

    The article explores student responses to institutional changes to accommodate increasingly diverse students into a cohesive community. It deals with student perceptions of current campus practices, social interaction, their interpretations of these, and how these relate to their experiences. It argues that, while the university has excelled in…

  10. PET/MRI: a novel hybrid imaging technique: major clinical indications and preliminary experience in Brazil; PET/RM: um novo metodo de imagem hibrida: principais indicacoes clinicas e experiencia preliminar no Brasil

    Energy Technology Data Exchange (ETDEWEB)

    Vitor, Taise; Martins, Karine Minaif; Ionescu, Tudor Mihai and others, E-mail: taisevitor@gmail.com [Hospital Israelita Albert Einstein, Sao Paulo, SP (Brazil)

    2017-04-01

    In recent years, medical imaging with hybrid techniques has widely accepted and employed in clinical routine. PET/MRI offers significant advantages, including excellent contrast and resolution and reduced ionizing radiation, as compared to well-established PET/ CT. Therefore, PET/MRI is a promising modality for oncologic imaging of some regions, such as brain, head and neck, liver and pelvis. This article set out to analyze clinical conditions that could benefit from PET/MRI imaging based on our caseload. The potential of PET/MRI to become the imaging modality of choice for assessment of neurologic and oncologic conditions associated with soft tissues is highlighted. Clinical aspects of PET/MRI and its application to clinical cases are illustrated with examples extracted from the authors' preliminary experience. (author)

  11. Spatio-temporal variation in contrasting effects of resident vegetation on establishment, growth and reproduction of dry grassland plants: implications for seed addition experiments.

    Science.gov (United States)

    Knappová, Jana; Knapp, Michal; Münzbergová, Zuzana

    2013-01-01

    Successful establishment of plants is limited by both biotic and abiotic conditions and their interactions. Seedling establishment is also used as a direct measure of habitat suitability, but transient changes in vegetation might provide windows of opportunity allowing plant species to colonize sites which otherwise appear unsuitable. We aimed to study spatio-temporal variability in the effects of resident vegetation on establishment, growth and reproduction of dry grassland species in abandoned arable fields representing potentially suitable habitats. Seeds were sown in disturbed (bare of vegetation and roots) and undisturbed plots in three fields abandoned in the last 20 years. To assess the effects of temporal variation on plant establishment, we initiated our experiments in two years (2007 and 2008). Seventeen out of the 35 sown species flowered within two years after sowing, while three species completely failed to become established. The vegetation in the undisturbed plots facilitated seedling establishment only in the year with low spring precipitation, and the effect did not hold for all species. In contrast, growth and flowering rate were consistently much greater in the disturbed plots, but the effect size differed between the fields and years of sowing. We show that colonization is more successful when site opening by disturbance coincide with other suitable conditions such as weather or soil characteristics. Seasonal variability involved in our study emphasizes the necessity of temporal replication of sowing experiments. Studies assessing habitat suitability by seed sowing should either involve both vegetation removal treatments and untreated plots or follow the gradient of vegetation cover. We strongly recommend following the numbers of established individuals, their sizes and reproductive success when assessing habitat suitability by seed sowing since one can gain completely different results in different phases of plant life cycle.

  12. Experiences with establishing and implementing learning management system and computer-based test system in medical college.

    Science.gov (United States)

    Park, Joo Hyun; Son, Ji Young; Kim, Sun

    2012-09-01

    The purpose of this study was to establish an e-learning system to support learning in medical education and identify solutions for improving the system. A learning management system (LMS) and computer-based test (CBT) system were established to support e-learning for medical students. A survey of 219 first- and second-grade medical students was administered. The questionnaire included 9 forced choice questions about the usability of system and 2 open-ended questions about necessary improvements to the system. The LMS consisted of a class management, class evaluation, and class attendance system. CBT consisted of a test management, item bank, and authoring tool system. The results of the survey showed a high level of satisfaction in all system usability items except for stability. Further, the advantages of the e-learning system were ensuring information accessibility, providing constant feedback, and designing an intuitive interface. Necessary improvements to the system were stability, user control, readability, and diverse device usage. Based on the findings, suggestions for developing an e-learning system to improve usability by medical students and support learning effectively are recommended.

  13. Establishing the boundaries and building bridges: a literature review on ecological theory: implications for research into the refugee parenting experience.

    Science.gov (United States)

    Williams, Nombasa

    2010-03-01

    Currently an ecological model for conceptualizing and capturing the refugee parenting experience is lacking. After an extensive review of the literature related to the usages of Bronfenbrenner's ecological model of child development, a gap was found in knowledge and research centred on describing the environment of pre-resettlement (i.e. pre-flight, flight, migration, camp) contexts and their impact on refugee parents and carer experiences. The culture of the refugee parenting experience may be characterized by disruptions in and alterations to family structure and organization; values and norms; and gender roles. This paper begins by examining the definition and usages of existing ecological frameworks in the 20th and 21st century. Particular attention is drawn to the gaps in the existing literature and an ecological model is offered. The paper concludes with a discussion of the implications for practice. The outcomes of this paper suggest the need for practitioners, policymakers and researchers to engage and develop culturally competent, relevant and appropriate interventions (i.e. reconciling differing beliefs and behaviours concerning child-rearing practices; affirming positive parenting practices of these families during engagement protocols and processes; adopting a strengths-based orientation) in the area of child protection whilst at the same time safeguarding and promoting the welfare of children within pre- and post-resettlement contexts.

  14. A somatostatin-secreting cell line established from a human pancreatic islet cell carcinoma (somatostatinoma): release experiment and immunohistochemical study.

    Science.gov (United States)

    Iguchi, H; Hayashi, I; Kono, A

    1990-06-15

    Production and secretion of somatostatin (SRIF) were studied using a carcinoembryonic antigen (CEA)-producing cell line (QGP-1) established from a human pancreatic islet cell carcinoma. High concentrations of SRIF (274 +/- 51 ng/mg of protein, mean +/- SD, n = 5) and CEA (3083 +/- 347 ng/mg of protein, mean +/- SD, n = 5) were present in QGP-1 cells, and the basal secretion rates of SRIF and CEA by the cells (n = 5) were 46.4 +/- 4.8 and 1690 +/- 78 pg/10(5) cells/h, respectively. Immunohistochemical studies revealed the presence of SRIF in xenografts of QGP-1 cells and colocalization of SRIF and CEA. Secretion of SRIF by QGP-1 cells was stimulated in the presence of high K+ (50 mmol) and theophylline (10 mmol), but arginine (10 mmol) and glucose (300 mg/dl) had no effect on the SRIF secretion. The QGP-1 cell line may be useful for studying the regulation mechanism of SRIF secretion.

  15. Physical Education as a territory to possible gender establishment: school experiences of transvestites, transexuals and transgender people

    Directory of Open Access Journals (Sweden)

    Neil Franco

    2016-05-01

    Full Text Available The Physical Education class at school interpreted through the experiences of the people who go beyond and/or live on the borders of gender is the focus of this study. It highlights considerations triggered by the analysis of the folder “A travesti e [o/a] educador[/a]” – about the insertion of these subjects in the Physical Education class –, correlated to bibliographic sources, interviews and questionnaires given to transvestite, transexuals and transgender brazilian teachers. It was concluded that, not unlike the school as a whole, Physical Education is also a space that exalts the incoherence between the reality of the educational routine and the norms that determine the school as a manager of inclusion.

  16. Management of complaints in blood establishments: thirteen years of experience at the Croatian Institute of Transfusion Medicine.

    Science.gov (United States)

    Vuk, Tomislav; Barišić, Marijan; Očić, Tihomir; Đogić, Vesna; Bingulac-Popović, Jasna; Sarlija, Dorotea; Balija, Melita; Jukić, Irena

    2012-07-01

    The aim of the study is to present the results and experience in the management of complaints in a transfusion service in order to draw attention to the importance of this segment of quality management and to stimulate publication of other studies on the topic. This study is based on data from the Croatian Institute of Transfusion Medicine obtained by analysis of complaints recorded during a 13-year period (1998-2010). The distribution of the types and frequencies of complaints is presented, along with the level of their justifiability and criticality. The dynamics of the complaints is analysed overall and within particular categories. In addition, corrective actions and other factors that may have influenced the trends observed are discussed. During the study period, 817 complaints were received, most of which (40.9%) referred to the positive direct antiglobulin test in red cell concentrates, followed by blood product issuing and distribution (12.9%) and blood product quality (9.4%). Of the 817 complaints, 177 (21.7%) were assessed as serious and 645 (78.9%) as justified based on the testing performed. Data collected by systematic recording and analysis of complaints provide a basis for problem identification, implementation of corrective and preventive actions, and improvement of product and service quality, and, thereby, customer satisfaction.

  17. A three-dimensional variational data assimilation system for the South China Sea: preliminary results from observing system simulation experiments

    Science.gov (United States)

    Peng, Shiqiu; Zeng, Xuezhi; Li, Zhijin

    2016-05-01

    A three-dimensional variational data assimilation (3DVAR) system based on the Regional Ocean Modeling System (ROMS) is established for the South China Sea (SCS). A set of Observing System Simulation Experiments (OSSEs) are performed to evaluate the performance of this data assimilation system and investigate the impacts of different types of observations on representation of three-dimensional large-scale circulations and meso-scale eddies in the SCS. The pseudo-observations that are examined include sea surface temperatures (SSTs), sea surface heights (SSHs), sparse temperature/salinity (T/S) profiles, sea surface velocities (SSVs), and sea surface salinities (SSSs). The results show that SSHs can extend their impacts into the subsurface or even the deep ocean while other surface observations only have impacts within surface mixed layer. SSVs have similar impacts though confined to their spatial coverage, suggesting that SSVs could be a substitute of SSHs nearshore where SSHs are of poor quality. Despite their sparseness, the T/S profiles improve the representation of the temperature and salinity structures below the mixed layer, and a combination of T/S profiles with surface observations leads to a better representation of the meso-scale eddies. Based on the OSSE results, an affordable observing network for the SCS in the near future is proposed.

  18. Experience and BCC subtypes as determinants of MAL-PDT response: preliminary results of a national Brazilian project.

    Science.gov (United States)

    Ramirez, Dora P; Kurachi, Cristina; Inada, Natalia M; Moriyama, Lilian T; Salvio, Ana G; Vollet Filho, José D; Pires, Layla; Buzzá, Hilde H; de Andrade, Cintia Teles; Greco, Clovis; Bagnato, Vanderlei S

    2014-03-01

    Non-melanoma skin cancer is the most prevalent cancer type in Brazil and worldwide. Photodynamic therapy (PDT) is a noninvasive technique with excellent cosmetic outcome and good curative results, when used for the initial stages of skin cancer. A Brazilian program was established to determine the efficacy of methyl aminolevulinate (MAL)-PDT, using Brazilian device and drug. The equipment is a dual device that combines the photodiagnosis, based on widefield fluorescence, and the treatment at 630nm. A protocol was defined for the treatment of basal cell carcinoma with 20% MAL cream application. The program also involves the training of the medical teams at different Brazilian regions, and with distinct facilities and previous PDT education. In this report we present the partial results of 27 centers with 366 treated BCC lesions in 294 patients. A complete response (CR) was observed in 76.5% (280/366). The better response was observed for superficial BCC, with CR 160 lesions (80.4%), when compared with nodular or pigmented BCC. Experienced centers presented CR of 85.8% and 90.6% for superficial and nodular BCC respectively. A high influence of the previous doctor experience on the CR values was observed, especially due to a better tumor selection.

  19. Literatura infantil e experiências cotidianas: relações estabelecidas por crianças = Children's literature and everyday experiences: relationships established by children

    Directory of Open Access Journals (Sweden)

    Samori, Debora Perillo

    2012-01-01

    Full Text Available Este artigo tem como objetivo investigar algumas relações estabelecidas entre crianças, suas experiências cotidianas e literatura infantil. Foram utilizados dados parciais de uma dissertação de mestrado com base no referencial de pesquisa com crianças e na abordagem etnográfica para o acompanhamento de um grupo do 1º ano do ensino fundamental (escola municipal de são paulo. Observação, diário de campo e entrevistas coletivas com crianças foram os instrumentos de coleta de dados. Para descrição densa e interpretação dos dados (geertz, 2011 utilizaram-se referências teóricas dos estudos interpretativos da infância com base nos conceitos de agência coletiva (mayall, 2002; corsaro, 1997, reprodução interpretativa e cultura de pares (corsaro, 1997, 2005, 2011. Do campo da literatura utilizaram-se os conceitos de função humanizadora da literatura (cândido, 1972; 2004, estética da recepção (jauss, 1994, atividade do leitor (zilberman, 2003, dentre outros

  20. Target sequencing, cell experiments, and a population study establish endothelial nitric oxide synthase (eNOS) gene as hypertension susceptibility gene.

    Science.gov (United States)

    Salvi, Erika; Kuznetsova, Tatiana; Thijs, Lutgarde; Lupoli, Sara; Stolarz-Skrzypek, Katarzyna; D'Avila, Francesca; Tikhonoff, Valerie; De Astis, Silvia; Barcella, Matteo; Seidlerová, Jitka; Benaglio, Paola; Malyutina, Sofia; Frau, Francesca; Velayutham, Dinesh; Benfante, Roberta; Zagato, Laura; Title, Alexandra; Braga, Daniele; Marek, Diana; Kawecka-Jaszcz, Kalina; Casiglia, Edoardo; Filipovsky, Jan; Nikitin, Yuri; Rivolta, Carlo; Manunta, Paolo; Beckmann, Jacques S; Barlassina, Cristina; Cusi, Daniele; Staessen, Jan A

    2013-11-01

    A case-control study revealed association between hypertension and rs3918226 in the endothelial nitric oxide synthase (eNOS) gene promoter (minor/major allele, T/C allele). We aimed at substantiating these preliminary findings by target sequencing, cell experiments, and a population study. We sequenced the 140-kb genomic area encompassing the eNOS gene. In HeLa and HEK293T cells transfected with the eNOS promoter carrying either the T or the C allele, we quantified transcription by luciferase assay. In 2722 randomly recruited Europeans (53.0% women; mean age 40.1 years), we studied blood pressure change and incidence of hypertension in relation to rs3918226, using multivariable-adjusted models. Sequencing confirmed rs3918226, a binding site of E-twenty six transcription factors, as the single nucleotide polymorphism most closely associated with hypertension. In T compared with C transfected cells, eNOS promoter activity was from 20% to 40% (Phypertension. The hazard ratio and attributable risk associated with TT homozygosity were 2.04 (CI, 1.24-3.37; P=0.0054) and 51.0%, respectively. In conclusion, rs3918226 in the eNOS promoter tags a hypertension susceptibility locus, TT homozygosity being associated with lesser transcription and higher risk of hypertension.

  1. Preliminary experience in the monitoring of geothermal probes by borehole logging; Erste Erfahrungen bei der bohrlochgeophysikalischen Ueberpruefung von Erdwaermesonden

    Energy Technology Data Exchange (ETDEWEB)

    Baumann, Karsten [Bohrlochmessung-Storkow GmbH, Storkow (Germany)

    2010-05-15

    Authorities as well as waterworks experts have long been calling for a control strategy to ensure that groundwater protection is considered in geothermal projects. So far, control options for geothermal probes were lacking, which raised doubts about the efficiency of sealing. Waterworks experts also were unable to understand why new groundwater wells or groundwater measuring fonts are subject to careful control via geophysical borehole logs while geothermal probes with a depth of 100 m and more can be installed nearby without adequate monitoring. The contribution presents a preliminary approach for monitoring and testing of shallow geothermal probes. (orig.)

  2. Visualization of periventricular collaterals in moyamoya disease with flow-sensitive black-blood magnetic resonance angiography: preliminary experience.

    Science.gov (United States)

    Funaki, Takeshi; Fushimi, Yasutaka; Takahashi, Jun C; Takagi, Yasushi; Araki, Yoshio; Yoshida, Kazumichi; Kikuchi, Takayuki; Miyamoto, Susumu

    2015-01-01

    Fragile abnormal collaterals in moyamoya disease, known as "moyamoya vessels," have rarely been defined. While flow-sensitive black-blood magnetic resonance angiography (FSBB-MRA) is a promising technique for visualizing perforating arteries, as of this writing no other reports exist regarding its application to moyamoya disease. Six adults with moyamoya disease underwent FSBB-MRA. It depicted abnormal collaterals as extended lenticulostriate, thalamic perforating, or choroidal arteries, which were all connected to the medullary or insular artery in the periventricular area and supplied the cortex. This preliminary case series illustrates the potential for FSBB-MRA to reveal abnormal moyamoya vessels, which could be reasonably defined as periventricular collaterals.

  3. Establishing a regional network of academic centers to support decision making for new vaccine introduction in Latin America and the Caribbean: the ProVac experience.

    Science.gov (United States)

    Toscano, C M; Jauregui, B; Janusz, C B; Sinha, A; Clark, A D; Sanderson, C; Resch, S; Ruiz Matus, C; Andrus, J K

    2013-07-02

    The Pan American Health Organization's ProVac Initiative, designed to strengthen national decision making regarding the introduction of new vaccines, was initiated in 2004. Central to realizing ProVac's vision of regional capacity building, the ProVac Network of Centers of Excellence (CoEs) was established in 2010 to provide research support to the ProVac Initiative, leveraging existing capacity at Latin American and Caribbean (LAC) universities. We describe the process of establishing the ProVac Network of CoEs and its initial outcomes and challenges. A survey was sent to academic, not-for-profit institutions in LAC that had recently published work in the areas of clinical decision sciences and health economic analysis. Centers invited to join the Network were selected by an international committee on the basis of the survey results. Selection criteria included academic productivity in immunization-related work, team size and expertise, successful collaboration with governmental agencies and international organizations, and experience in training and education. The Network currently includes five academic institutions across LAC. Through open dialog and negotiation, specific projects were assigned to centers according to their areas of expertise. Collaboration among centers was highly encouraged. Faculty from ProVac's technical partners were assigned as focal points for each project. The resulting work led to the development and piloting of tools, methodological guides, and training materials that support countries in assessing existing evidence and generating new evidence on vaccine introduction. The evidence generated is shared with country-level decision makers and the scientific community. As the ProVac Initiative expands to other regions of the world with support from immunization and public health partners, the establishment of other regional and global networks of CoEs will be critical. The experience of LAC in creating the current network could benefit the

  4. Challenges of establishing a Community Advisory Board (CAB in a low-income, low-resource setting: experiences from Bagamoyo, Tanzania

    Directory of Open Access Journals (Sweden)

    Shubis Kafuruki

    2009-06-01

    Full Text Available Abstract Objective Community Advisory Boards are now seen as standard practice for clinical vaccine and drug trials worldwide. In the past, most Community Advisory Boards (CABs were established by activists and lobbyists to monitor HIV/AIDS vaccine and drug trials in developed countries. In Africa the first CAB was established in Uganda in 1990 in conjunction with an HIV vaccine project and has since been followed by others in South Africa, Zimbabwe, and Kenya. In 2007, the Bagamoyo branch of the Ifakara Health Institute initiated the formation of a CAB. The aim was to properly educate and empower elected CAB members to become full partners in all research activities concerning the public within the Bagamoyo area. Methods and Results Beginning in 2007, staff visited each of the 24 villages within the study area to inform the communities about the proposed CAB and asked them to elect two individuals to represent their village on the CAB. The first attempt was hampered by community leaders selecting themselves, which led to inconsistent attendance, gender imbalance, and political infighting. New criteria for the selection of representatives were implemented to exclude governmental leaders, illiterate representatives and to promote a one-to-one gender balance. The newly appointed representatives underwent training and have participated in CAB meetings largely devoid of the negative issues previously encountered. Conclusion The successfully established CAB has led to improved relations with the community and facilitated the recruitment of study subjects. Our experiences show that, it is possible to establish a non-specific CAB in a low-income setting.

  5. Paranormal experience and the COMT dopaminergic gene: a preliminary attempt to associate phenotype with genotype using an underlying brain theory.

    Science.gov (United States)

    Raz, Amir; Hines, Terence; Fossella, John; Castro, Daniella

    2008-01-01

    Paranormal belief and suggestibility seem related. Given our recent findings outlining a putative association between suggestibility and a specific dopaminergic genetic polymorphism, we hypothesized that similar exploratory genetic data may offer supplementary insights into a similar correlation with paranormal belief. With more affordable costs and better technology in the aftermath of the human genome project, genotyping is increasingly ubiquitous. Compelling brain theories guide specific research hypotheses as scientists begin to unravel tentative relationships between phenotype and genotype. In line with a dopaminergic brain theory, we tried to correlate a specific phenotype concerning paranormal belief with a dopaminergic gene (COMT) known for its involvement in prefrontal executive cognition and for a polymorphism that is positively correlated with suggestibility. Although our preliminary findings are inconclusive, the research approach we outline should pave the road to a more scientific account of elucidating paranormal belief.

  6. Predicting relatedness and self-definition depressive experiences in aging women based on personality traits: a preliminary study.

    Science.gov (United States)

    Henriques-Calado, Joana; Duarte-Silva, Maria Eugénia; Campos, Rui C; Sacoto, Carlota; Keong, Ana Marta; Junqueira, Diana

    2013-01-01

    As part of the research relating personality and depression, this study seeks to predict depressive experiences in aging women according to Sidney Blatt's perspective based on the Five-Factor Model of Personality. The NEO-Five Factor Inventory and the Depressive Experiences Questionnaire were administered. The domains Neuroticism, Agreeableness, and Conscientiousness predicted self-criticism, explaining 68% of the variance; the domains Neuroticism and Extraversion predicted dependency, explaining 62% of the variance. The subfactors Neediness and Connectedness were differently related to personality traits. These findings are relevant to the research relating personality and anaclitic / introjective depressive experiences in late adulthood.

  7. Bring Your Own Device Technology: Preliminary Results from a Mixed Methods Study to Explore Student Experience of In-Class Response Systems in Post-Secondary Education

    Directory of Open Access Journals (Sweden)

    Matthew Numer

    2015-02-01

    Full Text Available This research examines the effectiveness of Bring Your Own Device (BYOD technology in a postsecondary classroom. Despite recent advances in the technological tools available to educators, there is a significant gap in the literature regarding student efficacy, engagement and contribution to learning. This paper will present the preliminary findings of the first phases of an evaluation project measuring student interaction with BYOD technology in a large group setting. Employing a mixed methods design, the findings from two focus groups and two online surveys will be discussed. This project involved students in the Winter and Fall 2014 semesters of a fourth year Human Sexuality course which has enrolment of approximately 400 per semester. The findings suggest that BYOD technology contributes to student engagement and participation in the classroom setting. Further, the findings suggest that students are comfortable in using this tool, and perceived the experience as enjoyable.

  8. Preliminary experiments on the growth of plants exposed to DC corona discharge in a hydroponics. Chokuryu corona hodenkadeno suiko sanbaini yoru shokubutsu seiikuno yobiteki kento

    Energy Technology Data Exchange (ETDEWEB)

    Shigemitsu, Tsukasa; Watanabe, Yasunori

    1988-01-01

    For the purpose of utilizing electrical phenomena to agriculture fields, preliminary experiments were carried out hydroponically to evaluate especially the effects of ion by DC corona discharge on the growth of plants such as lettuce or radish. The influences of various shapes of discharge electrodes on a water evaporation rate, ozone production rate and ion current change were studied, and the indirect stimulation effects on plants by more water evaporation under discharge, and the direct stimulation effects on plants with discharge by the electrode fixed 45cm above plants were studied. As a result, the water evaporation rate was 2 or 3 times more than that of control plots by positive or negative corona discharge, however, for the growth of plants, no remarkable direct or indirect stimulation effects by discharge were observed. As subjects, the clarification of water behavior change under discharge and of effects on plants in cellular level were pointed out to be necessary. (14 figs, 12 tabs, 12 refs)

  9. Superfluid helium orbital resupply - The status of the SHOOT flight experiment and preliminary user requirements. [Superfluid Helium On-Orbit Transfer

    Science.gov (United States)

    Dipirro, Michael J.; Kittel, Peter

    1989-01-01

    The Superfluid Helium On-Orbit Transfer (SHOOT) flight experiment is designed to demonstrate the components and techniques necessary to resupply superfluid helium to satellites or Space Station based facilities. A top level description as well as the development status of the critical components to be used in SHOOT are discussed. Some of these components include the thermomechanical pump, the fluid acquisition system, the normal helium and superfluid helium phase separators, Venturi flow meter, cryogenic valves, burst disks, and astronaut-compatible EVA coupler and transfer line. The requirements for the control electronics and software are given. A preliminary description of the requirements that must be met by a satellite requiring superfluid helium servicing is given. In particular, minimum and optimum plumbing arrangements are shown, transfer line flow impedance and heat input impacts are assessed, instrumentation is described, and performance parameters are considered.

  10. Experiência preliminar com novo filtro de veia cava: resultados de 15 implantes Preliminary experience with a new vena cava filter: results of 15 implantations

    Directory of Open Access Journals (Sweden)

    Winston B. Yoshida

    2008-09-01

    Full Text Available Este estudo apresenta resultados preliminares obtidos com um novo filtro permanente de veia cava, baseado no desenho de Greenfield, com três hastes prolongadas de um total de seis, para dar estabilidade central ao filtro na luz da veia cava. Neste artigo, relatamos sua avaliação clínica preliminar quanto à aplicabilidade, eficácia e segurança. De agosto de 2004 a dezembro de 2006, 15 filtros foram implantados em nove homens e seis mulheres, com idades variando de 38 a 79 anos (média de 57,8 anos. O acesso foi feito sempre por via transjugular. As indicações foram: trombose venosa proximal, com contra-indicação de anticoagulação em 12 pacientes; complicações hemorrágicas com anticoagulação em dois pacientes; e embolia pulmonar, apesar de anticoagulação adequada, em um paciente. Os filtros foram avaliados quanto à liberação, inclinação, mau posicionamento e perfuração de cava. No seguimento, avaliou-se trombose no local de acesso, tromboembolismo venoso recorrente, migração do filtro e trombose de cava pelo ultra-som. Nenhum paciente recebeu anticoagulantes no seguimento. O filtro foi liberado com sucesso em todos os casos sem mau posicionamento, inclinação, perfuração ou trombose de acesso. Os pacientes foram seguidos entre 3 e 23 meses (média de 11 meses. Nenhum paciente teve recorrência de tromboembolismo venoso. Não houve casos de trombose de veia cava ou migração do filtro. Óbito ocorreu em sete casos, todos relacionados com a moléstia de base. Os resultados preliminares indicam potencial eficácia e segurança do uso do novo filtro no período estudado.This study presents preliminary results obtained from a new permanent filter, based on Greenfield's filter design, with prolongations on three of six struts to stabilize it centrally in the vena caval lumen. The preliminary clinical evaluation of the filter with regard to feasibility, efficacy and safety is reported. From August 2004 to December 2006

  11. Study on critical heat flux in narrow rectangular channel with repeated-rib roughness. 1. Experimental facility and preliminary experiments

    Energy Technology Data Exchange (ETDEWEB)

    Kinoshita, Hidetaka; Terada, Atsuhiko; Kaminaga, Masanori; Hino, Ryutaro [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2001-10-01

    In the design of a spallation target system, the water cooling system, for example a proton beam window and a safety hull, is used with narrow channels, in order to remove high heat flux and prevent lowering of system performance by absorption of neutron. And in narrow channel, heat transfer enhancement using 2-D rib is considered for reduction the cost of cooling component and decrease inventory of water in the cooling system, that is, decrease of the amount of irradiated water. But few studies on CHF with rib have been carried out. Experimental and analytical studies with rib-roughened test section, in 10:1 ratio of pitch to height, are being carried out in order to clarify the CHF in rib-roughened channel. This paper presents the review of previous researches on heat transfer in channel with rib roughness, overview of the test facility and the preliminary experimental and analytical results. As a result, wall friction factors were about 3 times as large as that of smooth channel, and heat transfer coefficients are about 2 times as large as that of smooth channel. The obtained CHF was as same as previous mechanistic model by Sudo. (author)

  12. MR elastography of the liver at 3.0 T in diagnosing liver fibrosis grades; preliminary clinical experience

    Energy Technology Data Exchange (ETDEWEB)

    Yoshimitsu, Kengo; Mitsufuji, Toshimichi; Shinagawa, Yoshinobu; Fujimitsu, Ritsuko; Morita, Ayako; Urakawa, Hiroshi; Takano, Koichi [Fukuoka University, Department of Radiology, Fukuoka (Japan); Hayashi, Hiroyuki [Fukuoka University, Department of Pathology, Faculty of Medicine, Fukuoka (Japan)

    2016-03-15

    To clarify the usefulness of 3.0-T MR elastography (MRE) in diagnosing the histological grades of liver fibrosis using preliminary clinical data. Between November 2012 and March 2014, MRE was applied to all patients who underwent liver MR study at a 3.0-T clinical unit. Among them, those who had pathological evaluation of liver tissue within 3 months from MR examinations were retrospectively recruited, and the liver stiffness measured by MRE was correlated with histological results. Institutional review board approved this study, waiving informed consent. There were 70 patients who met the inclusion criteria. Liver stiffness showed significant correlation with the pathological grades of liver fibrosis (rho = 0.89, p < 0.0001, Spearman's rank correlation). Areas under the receiver operating characteristic curve were 0.93, 0.95, 0.99 and 0.95 for fibrosis score greater than or equal to F1, F2, F3 and F4, with cut-off values of 3.13, 3.85, 4.28 and 5.38 kPa, respectively. Multivariate analysis suggested that grades of necroinflammation also affected liver stiffness, but to a significantly lesser degree as compared to fibrosis. 3.0-T clinical MRE was suggested to be sufficiently useful in assessing the grades of liver fibrosis. (orig.)

  13. Analysis of the η′ photoproduction off the proton and preliminary beam asymmetry results at the GRAAL experiment

    Directory of Open Access Journals (Sweden)

    Mandaglio G.

    2014-05-01

    Full Text Available Differential and total cross section measurements on η′ photoproduction were published by the CLAS Collaboration (M. Dugger et al., Phys.Rev.Lett.96, 062001 (2006 and M. Williams et al., Phys.Rev.C80, 045213 (2009 for center-of-mass energies from near the threshold up to 2.84 GeV, and by the CB-ELSA-TAPS Collaboration (V. Crede et al., Phys.Rev.C80, 055202 (2009 up to 2.36 GeV and also making a precise threshold scan of the differential cross section in the 1446 – 1527.4 MeV γ beam energy range. However, the wide information about reaction cross sections are not sufficient to understand the role of resonances involved in the process. Different theoretical works stressed the importance to have also polarization observables in order to solve the ambiguity in the choice of the parameters used in their models. We present the analysis of the η′ photoproduction off the proton, identifying the meson via the γγ, π0π0η, and π+π−η decay modes by using the GRAAL apparatus; and we show the preliminary GRAAL results on the beam asymmetry Σ from the threshold (1.446 GeV up to 1.5 GeV.

  14. Our experience in the diagnosis of intraocular tumours by a B-scan computerized system and angiodynography (Doppler). Preliminary results.

    Science.gov (United States)

    Falco, L; Esente, S; Fanfani, S; Pasarelli, N; Utari, S

    1992-01-01

    The authors compare the ultrasound diagnostic results of intraocular tumours by A/B-scans (Sonomed B 3000, Sonocare, Sonovision STT-100) with images obtained using computerized B-scan (Sonocare, Sonovision STT-100, Acoustic Tissue Typing ATT) and angiodynopgraphy systems (Quantum Philips). The Sonovision uses a computerized ultrasound spectrum analysis to assess the probability that a given lesion is a certain tumour, rather than another. The ATT system provides diagnostic probability for type B and type E melanoma, for haemangioma and metastatic carcinoma. The Quantum ultrasound equipment was developed for studying the heart and the major blood vessels. It is a colour Doppler that simplifies the Doppler technique, allowing it to study small anatomical parts such as tumour-like lesions of the eye. The Doppler technique ascertains the presence and the velocity of blood flow in the tumours. In presenting the preliminary results with the new techniques the authors are aware that the ATT system is not designed for some of the lesions under study (melanomas after conservative radiotherapy).

  15. Radiofrequency Kyphoplasty for the Treatment of Osteoporotic and Neoplastic Vertebral Body Fractures - Preliminary Experience and Clinical Results after 6 Months

    Directory of Open Access Journals (Sweden)

    Elgeti F

    2011-01-01

    Full Text Available Vertebroplasty and conventional kyphoplasty using a balloon or a stent are established methods for the treatment of painful osteoporotic or neoplastic vertebral compression fractures that are resistant to conservative medical treatment. Radiofrequency (RF kyphoplasty with ultra-high viscosity cement is an innovative method. It permits safe and effective treatment of painful osteoporotic and neoplastic vertebral compression fractures while preserving non-compromised cancellous bone.

  16. Laser bonding with ICG-infused chitosan patches: preliminary experiences in suine dura mater and vocal folds

    Science.gov (United States)

    Rossi, Francesca; Matteini, Paolo; Ratto, Fulvio; Pini, Roberto; Iacoangeli, Maurizio; Giannoni, Luca; Fortuna, Damiano; Di Cicco, Emiliano; Corbara, Sylwia; Dallari, Stefano

    2014-05-01

    Laser bonding is a promising minimally invasive approach, emerging as a valid alternative to conventional suturing techniques. It shows widely demonstrated advantages in wound treatment: immediate closuring effect, minimal inflammatory response and scar formation, reduced healing time. This laser based technique can overcome the difficulties in working through narrow surgical corridors (e.g. the modern "key-hole" surgery as well as the endoscopy setting) or in thin tissues that are impossible to treat with staples and/or stitches. We recently proposed the use of chitosan matrices, stained with conventional chromophores, to be used in laser bonding of vascular tissue. In this work we propose the same procedure to perform laser bonding of vocal folds and dura mater repair. Laser bonding of vocal folds is proposed to avoid the development of adhesions (synechiae), after conventional or CO2 laser surgery. Laser bonding application in neurosurgery is proposed for the treatment of dural defects being the Cerebro Spinal Fluid leaks still a major issue. Vocal folds and dura mater were harvested from 9-months old porks and used in the experimental sessions within 4 hours after sacrifice. In vocal folds treatment, an IdocyanineGreen-infused chitosan patch was applied onto the anterior commissure, while the dura mater was previously incised and then bonded. A diode laser emitting at 810 nm, equipped with a 600 μm diameter optical fiber was used to weld the patch onto the tissue, by delivering single laser spots to induce local patch/tissue adhesion. The result is an immediate adhesion of the patch to the tissue. Standard histology was performed, in order to study the induced photothermal effect at the bonding sites. This preliminary experimental activity shows the advantages of the proposed technique in respect to standard surgery: simplification of the procedure; decreased foreign-body reaction; reduced inflammatory response; reduced operating times and better handling in

  17. Measurement of hydrogen, helium, carbon and oxygen cosmic ray primaries: Preliminary results from the CREAM II experiment

    Science.gov (United States)

    Mognet, S. A. Isaac

    The direct measurement of the energy spectrum and composition of the incoming cosmic-ray flux at multi-TeV energies is of great interest. A feature located somewhere between 1000-10,000 TeV in the all-particle spectrum, referred to as the 'knee' characterized by a steepening of the power-law flux, has been observed by ground-based detectors for many years. It is believed to be related to an upper limit or change in efficiency of the Galactic accelerators of cosmic rays and/or properties of the propagation of cosmic rays in the Galaxy. Presented here is a preliminary analysis of the flux of primary H, He, C and O cosmic-ray species measured using the CREAM II instrument. This analysis is conducted using the Penn State-built Timing Charge Detector, distinct from other charge detectors used in alternative published CREAM II results. The second Antarctic flight of the CREAM instrument had a ~ 28 day flight in the 2005-2006 Antarctic flight season. The instrument was launched on December 16 th 2005 from Williams Field near McMurdo Station, Antarctica. The analysis presented here used events collected throughout the flight to calibrate the charge response of the Timing Charge Detector. High-energy events collected during the entire flight time (except for the first ~ 3.5 days which were used for high-voltage tuning) are also analyzed here. Also presented in this thesis is a novel optical simulation of the Timing Charge Detector used in the various flights of the CREAM instrument. The model suggests fundamental limitations on the timing resolution of the detector arising purely from photon propagation physics in the scintillation and light- guide elements.

  18. Effects of palliative care training program on knowledge, attitudes, beliefs and experiences among student physiotherapists: A preliminary quasi-experimental study

    Directory of Open Access Journals (Sweden)

    Senthil P Kumar

    2011-01-01

    Full Text Available Background: Physiotherapists play an inherent role in the multidisciplinary palliative care team. Existing knowledge, attitudes, beliefs and experiences influence their team participation in palliative care. Aims: The objective of this study was to assess the changes in knowledge, attitudes, beliefs and experiences among student physiotherapists who attended a palliative care training program. Settings and Design: Preliminary quasi-experimental study design, conducted at an academic institution. Materials and Methods: Fifty-two student physiotherapists of either gender (12 male, 40 female of age (20.51±1.78 years who attended a palliative care training program which comprised lectures and case examples of six-hours duration participated in this study. The study was performed after getting institutional approval and obtaining participants′ written informed consent. The lecture content comprised WHO definition of palliative care, spiritual aspects of life, death and healing, principles, levels and models of palliative care, and role of physiotherapists in a palliative care team. The physical therapy in palliative care-knowledge, attitudes, beliefs and experiences scale (PTiPC-KABE Scale- modified from palliative care attitudes scale were used for assessing the participants before and after the program. Statistical Analysis: Paired t-test and Wilcoxon signed rank test at 95% confidence interval using SPSS 11.5 for Windows. Results: Statistically significant differences (P<0.05 were noted for all four subscales- knowledge (7.84±4.61 points, attitudes (9.46±8.06 points, beliefs (4.88±3.29 points and experiences (15.8±11.28 points out of a total score of 104 points. Conclusions: The focus-group training program produced a significant positive change about palliative care in knowledge, attitudes, beliefs and experiences among student physiotherapists.

  19. Incorporating field wind data into FIRETEC simulations of the International Crown Fire Modeling Experiment (ICFME): preliminary lessons learned

    Science.gov (United States)

    Rodman Linn; Kerry Anderson; Judith Winterkamp; Alyssa Broos; Michael Wotton; Jean-Luc Dupuy; Francois Pimont; Carleton Edminster

    2012-01-01

    Field experiments are one way to develop or validate wildland fire-behavior models. It is important to consider the implications of assumptions relating to the locality of measurements with respect to the fire, the temporal frequency of the measured data, and the changes to local winds that might be caused by the experimental configuration. Twenty FIRETEC simulations...

  20. Cancer rehabilitation education during physical medicine and rehabilitation residency: preliminary data regarding the quality and quantity of experiences.

    Science.gov (United States)

    Raj, Vishwa S; Balouch, Jamal; Norton, James H

    2014-05-01

    The purpose of this study was to gather descriptive information from residency program directors regarding characteristics of the education and experiences of resident physicians in oncology rehabilitation. The program directors responded to a 28-question survey. Information collected included general descriptors of residency programs, oncology rehabilitation services lines within the institution, educational and clinical opportunities for trainees, and perceptions of quality for oncology experiences. Thirty-eight responses, with a response rate of 48%, were recorded. Thirty-two percent of the programs did not have any dedicated faculty for cancer rehabilitation. A majority of the respondents felt that cancer rehabilitation should be an important component of the curriculum. Sixty-six percent of the programs admitted only one to two cancer diagnoses to their inpatient units per week, and 26% had outpatient clinics that focused specifically on rehabilitation needs for oncology patients. A majority of the programs felt that experiences were only average and that residents do not receive adequate exposure to cancer rehabilitation during their training. Although cancer rehabilitation is considered an important area of education, quality and quantity of experiences may be improved. Several opportunities may exist to improve such exposure in anticipation of serving the functional needs for a growing population of cancer survivors.

  1. Changes in dream experience in relation with antidepressant escitalopram treatment in depressed female patients: a preliminary study.

    Science.gov (United States)

    Quartini, Adele; Anastasia, Annalisa; Bersani, Francesco Saverio; Melcore, Claudia; Albano, Gabriella; Colletti, Chiara; Valeriani, Giuseppe; Bersani, Giuseppe

    2014-01-01

    Sleep disturbances have long been considered as a cardinal symptom of endogenous depression and dreams in depressed patients usually differ from those of healthy people. The aim of the present study was to investigate dream subjective experiences and their modifications in relation to clinical response in a group of escitalopram-treated depressed patients. Twenty-seven female patients meeting DSM-IV-TR criteria for Major Depressive Disorder (MDD) and starting SSRI therapy were included in the study. Data about psychopathological status and dreaming subjective experiences were collected at baseline (T0), 4 weeks after the beginning of the treatment (T1) and after further 4 weeks of therapy (T2). At T0 dream experience was impaired and negatively toned. Concomitantly with the decrease of symptoms severity, the 8-week escitalopram treatment yielded to significant improvements in the recall of both quantity and quality of dreams; those patients whit lower clinical benefits kept on reporting impaired dream experiences. The results of the present study evidence how the changes in some specific dreaming characteristics, such as the subjective recall of dream activity, the dream recall quality, the dream emotional content and the dream complexity represent reliable markers of the effectiveness of antidepressant therapy.

  2. FACTORS FOR AND AGAINST ESTABLISHING AND WORKING IN PRIVATE PRACTICE CORRELATED WITH WORK-RELATED BEHAVIOR AND EXPERIENCE PATTERNS OF GERMAN PHYSICIANS IN SCHLESWIG-HOLSTEIN: A 2-YEAR LONGITUDINAL STUDY

    National Research Council Canada - National Science Library

    Edgar Voltmer; Claudia Spahn; Erica Frank

    2017-01-01

    Abstract Objectives: To identify factors in favor of or against establishing and working in private practice, to determine the quality of life and work-related behavior and experience patterns of German physicians...

  3. Preliminary Experience with the GORE(®) EXCLUDER(®) Iliac Branch Endoprosthesis for Common Iliac Aneurysm Endovascular Treatment.

    Science.gov (United States)

    Millon, Antoine; Della Schiava, Nellie; Arsicot, Matthieu; De Lambert, Alberic; Feugier, Patrick; Magne, Jean Luc; Lermusiaux, Patrick

    2016-05-01

    The aim of this study is to assess the safety and the short-term results of endovascular treatment of common iliac artery (CIA) aneurysms using the new GORE EXCLUDER iliac branch endoprosthesis (IBE) device. The study is a retrospective with prospective follow-up nonrandomized, single-arm evaluation. Patients with a CIA aneurysm (diameter >30 mm) extending to the iliac bifurcation underwent endovascular treatment with the Gore IBE. Anatomic and procedural data were collected. Computed tomography angiography (CTA) was performed within the 30 days after the procedure and every 6 month. Thirty-day and at least 6-months outcomes were investigated. From February 2014 to December 2014, 10 male patients with aneurysmal CIA (mean age 75 years old) underwent consecutive endovascular treatment with the Gore IBE. The CIA aneurysm (mean diameter 43.2 mm, range 32-49) treated with the Gore IBE was associated with an abdominal aortic aneurysm (AAA) in 5 patients. One patient had a previous AAA open repair. CIA aneurysm was bilateral in 5 patients. Preliminary procedure of internal iliac artery embolization was performed in 3 patients. Technical success rate of the Gore IBE implantation was 100% with a median fluoroscopy time of 35 min (range 12-64, ±16) and median contrast load of 150 mL (range 100-250, ±45). No perioperative complications were observed. Median length of stay was 4 days (range 3-7, ±2). One aortic type Ia endoleak was observed on the postoperative CT scan requiring an aortic extension at day 3. Branch patency was observed in all 10 patients at 1 month and 9 patients at 6 month. All CIA aneurysms were excluded without type Ib or type III endoleak. The technical success and short-term results demonstrate encouraging results and clinical benefits of the new GORE EXCLUDER IBE. A longer follow-up is needed to assess midterm and long-term results. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. Preliminary Results From the CAUGHT Experiment: Investigation of the North Central Andes Subsurface Using Receiver Functions and Ambient Noise Tomography

    Science.gov (United States)

    Ryan, J. C.; Ward, K. M.; Porter, R. C.; Beck, S. L.; Zandt, G.; Wagner, L. S.; Minaya, E.; Tavera, H.

    2011-12-01

    Jamie Ryan, Kevin M. Ward, Ryan Porter, Susan Beck, George Zandt, Lara Wagner, Estela Minaya, and Hernando Tavera The University of Arizona The University of North Carolina San Calixto Observatorio, La Paz, Bolivia IGP, Lima, Peru In order to investigate the interplay between crustal shortening, lithospheric removal, and surface uplift we have deployed 50 broadband seismometers in northwestern Bolivia and southern Peru as part of the interdisciplinary Central Andean Uplift and Geodynamics of High Topography (CAUGHT) project. The morphotectonic units of the central Andes from west to east, consist of the Western Cordillera, the active volcanic arc, the Altiplano, an internally drained basin (~4 km elevation), the Eastern Cordillera, the high peaks (~6 km elevation) of an older fold and thrust belt, the Subandean zone, the lower elevation active fold and thrust belt, and the foreland Beni basin. Between northwestern Bolivia and southern Peru, the Altiplano pinches out north of Lake Titicaca as the Andes narrow northward. The CAUGHT seismic instruments were deployed between 13° to 18° S latitudes to investigate the crust and mantle lithosphere of the central Andes in this transitional zone. In northwest Bolivia, perpendicular to the strike of the Andes, there is a total of 275 km of documented upper crustal shortening (15° to 17°S) (McQuarrie et al, 2008). Associated with the shortening is crustal thickening and possibly lithospheric removal as the thickening lithospheric root becomes unstable. An important first order study is to compare upper crustal shortening estimates with present day crustal thickness. To estimate crustal thickness, we have calculated receiver functions using an iterative deconvolution method and used common conversion point stacking along the same profile as the geologically based shortening estimates. In our preliminary results, we observed a strong P to S conversion corresponding to the Moho at approximately 60-65 km depth underneath the

  5. Preliminary experiments about the measure of the magnetic properties of a material by means of TDR probes

    Science.gov (United States)

    Persico, Raffaele

    2016-04-01

    In this contribution, the possibility of measuring possible magnetic properties of materials by means of a TDR probe is studied. A transmission line model is adopted and data in time and frequency domain are exploited together. Simulation results are shown, at the moment based on a bifilar line model. Magnetic properties of materials can be of interest for several applications. In particular, the presence of magnetic features in the soil or in any substance, might be associated to some contaminant (presumably containing some metallic element as iron, nickel or chromium [1]). This kind of pollution might occur close to some farms, especially regarding the dying of dresses, the production of some medicines, the tanning of leather issues. Moreover, modern agriculture puts in the soil several fertilizing substances, and there is a debate about the quantity of heavy metals spread in the terrain by these activities [2]. Still, some depuration-mud can be affected by an excessive presence of metallic elements, because of the presence of batteries, skins, varnishes, cosmetics, and so on [2]. Moreover, it is thought that the soil on the planet Mars might show magnetic properties [3]. Finally, in GPR prospecting, possible magnetic characteristics of the soil or of the targets might be of interest too [4], but they cannot be retrieved by means of only GPR data [5]. In the present paper, the results of a preliminary study are exposed with regard to the possibility to measure the magnetic properties of a material by mean of a TDR probe [6-7]. In particular a TDR probe is essentially a transmission line (a bifilar model will be exploited in this work) open at the end, form which most of the impinging energy (ideally the whole of thi energy in a lossless medium) is back reflected. In particular, this allows a customary measure of the propagation velocity in the medium if an impulsive signal is generated. In fact, the return time along a path of known length is measured. The

  6. Design and test of an extremely high resolution Timing Counter for the MEG II experiment: preliminary results

    CERN Document Server

    De Gerone, M; Ootani, W; Uchiyama, Y; Nishimura, M; Shirabe, S; Cattaneo, P W; Rossella, M

    2013-01-01

    The design and tests of Timing Counter elements for the upgrade of the MEG experiment, MEG II,is presented. The detector is based on several small plates of scintillator with a Silicon PhotoMultipliers dual-side readout. The optimisation of the single counter elements (SiPMs, scintillators, geometry) is described. Moreover, the results obtained with a first prototype tested at the Beam Test Facility (BTF) of the INFN Laboratori Nazionali di Frascati (LNF) are presented.

  7. Preliminary experience with transperitoneal laparoendoscopic single-site radical nephrectomy using a home-made single-port device in China

    Institute of Scientific and Technical Information of China (English)

    Bi Hai; Ma Lulin; Hou Xiaofei; Zhang Shudong; Wang Guoliang; Zhao Lei

    2014-01-01

    Background Laparoendoscopic single-site (LESS) surgery represents a technique to further reduce morbidity and scarring associated with surgery.We present our preliminary experience with transperitoneal LESS radical nephrectomy (RN) using a home-made single-port device in China.Methods From July 2010 to November 2011,eleven patients with renal tumor not greater than T2 underwent LESS-RN by an experienced laparoscopic surgeon.A home-made single-port device was used through a 5-cm umbilical incision.A combination of standard and articulating laparoscopic instruments was used.The sequence of steps of LESS-RN was similar to transperitoneal laparoscopic RN.Patient characteristics,perioperative variables and postoperative outcomes were recorded and analyzed.Results Except for two transperitoneal laparoscopic conversions and one hand-assisted laparoscopic conversion,the other procedures were completed successfully without conversion to open surgery.The mean operative time was 224.5 (155-297) minutes,estimated blood loss was 270.9 (50-900) ml,and hospital stay was 10.4 (5-15) days.The mean visual analog pain scale (VAPS) on the first postoperative day was 4.0/10.Final pathological analysis revealed renal cell carcinoma in all cases with a stage distribution of three T1a,five T1b,and three T2a tumors.With the mean followup period of 21.4 (12-28) months,all patients were alive without evidence of tumor recurrence or metastasis,and were satisfied with the appearance of the scars.Conclusion Transperitoneal LESS-RN using a home-made single-port device is technically feasible and safe in a selected group of patients (low body mass index and stage tumor) and has excellent cosmetic results.Although preliminary oncologic outcome is not compromised,the long-term evaluation of these patients is awaited.

  8. Soil Parameter Mapping and Ad Hoc Power Analysis to Increase Blocking Efficiency Prior to Establishing a Long-Term Field Experiment

    Directory of Open Access Journals (Sweden)

    Doug Collins

    2015-01-01

    Full Text Available The spatial heterogeneity of soil and weed populations poses a challenge to researchers. Unlike aboveground variability, below-ground variability is more difficult to discern without a strategic soil sampling pattern. While blocking is commonly used to control environmental variation, this strategy is rarely informed by data about current soil conditions. Fifty georeferenced sites were located in a 0.65 ha area prior to establishing a long-term field experiment. Soil organic matter (OM and weed seed bank populations were analyzed at each site and the spatial structure was modeled with semivariograms and interpolated with kriging to map the surface. These maps were used to formulate three strategic blocking patterns and the efficiency of each pattern was compared to a completely randomized design and a west to east model not informed by soil variability. Compared to OM, weeds were more variable across the landscape and had a shorter range of autocorrelation, and models to increase blocking efficiency resulted in less increase in power. Weeds and OM were not correlated, so no model examined improved power equally for both parameters. Compared to the west to east blocking pattern, the final blocking pattern chosen resulted in a 7-fold increase in power for OM and a 36% increase in power for weeds.

  9. Feasibility of establishing a biosafety level 3 tuberculosis culture laboratory of acceptable quality standards in a resource-limited setting: an experience from Uganda.

    Science.gov (United States)

    Ssengooba, Willy; Gelderbloem, Sebastian J; Mboowa, Gerald; Wajja, Anne; Namaganda, Carolyn; Musoke, Philippa; Mayanja-Kizza, Harriet; Joloba, Moses Lutaakome

    2015-01-15

    Despite the recent innovations in tuberculosis (TB) and multi-drug resistant TB (MDR-TB) diagnosis, culture remains vital for difficult-to-diagnose patients, baseline and end-point determination for novel vaccines and drug trials. Herein, we share our experience of establishing a BSL-3 culture facility in Uganda as well as 3-years performance indicators and post-TB vaccine trials (pioneer) and funding experience of sustaining such a facility. Between September 2008 and April 2009, the laboratory was set-up with financial support from external partners. After an initial procedure validation phase in parallel with the National TB Reference Laboratory (NTRL) and legal approvals, the laboratory registered for external quality assessment (EQA) from the NTRL, WHO, National Health Laboratories Services (NHLS), and the College of American Pathologists (CAP). The laboratory also instituted a functional quality management system (QMS). Pioneer funding ended in 2012 and the laboratory remained in self-sustainability mode. The laboratory achieved internationally acceptable standards in both structural and biosafety requirements. Of the 14 patient samples analyzed in the procedural validation phase, agreement for all tests with NTRL was 90% (P culture, identification, and drug susceptibility testing (DST). The annual culture workload was 7,636, 10,242, and 2,712 inoculations for the years 2010, 2011, and 2012, respectively. Other performance indicators of TB culture laboratories were also monitored. Scores from EQA panels included smear microscopy >80% in all years from NTRL, CAP, and NHLS, and culture was 100% for CAP panels and above regional average scores for all years with NHLS. Quarterly DST scores from WHO-EQA ranged from 78% to 100% in 2010, 80% to 100% in 2011, and 90 to 100% in 2012. From our experience, it is feasible to set-up a BSL-3 TB culture laboratory with acceptable quality performance standards in resource-limited countries. With the demonstrated quality of

  10. Preliminary drop-tower experiments on liquid-interface geometry in partially filled containers at zero gravity

    Science.gov (United States)

    Smedley, G.

    1990-01-01

    Plexiglass containers with rounded trapezoidal cross sections were designed and built to test the validity of Concus and Finn's existence theorem (1974, 1983) for a bounded free liquid surface at zero gravity. Experiments were carried out at the NASA Lewis two-second drop tower. Dyed ethanol-water solutions and three immiscible liquid pairs, with one liquid dyed, were tested. High-speed movies were used to record the liquid motion. Liquid rose to the top of the smaller end of the containers when the contact angle was small enough, in agreement with the theory. Liquid interface motion demonstrated a strong dependence on physical properties, including surface roughness and contamination.

  11. Bioaccumulation Experiments in Mussels Contaminated with the Food-Borne Pathogen Arcobacter butzleri: Preliminary Data for Risk Assessment

    Directory of Open Access Journals (Sweden)

    Donatella Ottaviani

    2013-01-01

    Full Text Available The aim of this study was to evaluate, at a laboratory scale, the ability of this microorganism to grow in seawater and bioaccumulate in mussels (Mytilus galloprovincialis maintained in constantly aerated tanks, containing twenty litres of artificial seawater. Three concentrations of A. butzleri LMG 10828T were tested (about 5×106 CFU/mL, 5×104 CFU/mL, and 5×102 CFU/mL. Following contamination, enumeration of A. butzleri was performed from water and mussels each day, for up to 96 h. Three contamination experiments with artificial seawater in absence of mussels were also performed in the same manner. In the experiments with mussels, A. butzleri declined in water of approximately 1 log every 24 h from the contamination. In artificial seawater without mussels the concentration of A. butzleri remained on the same logarithmic level in the first 48 h and then decreased of about 1 log every 24 hours. In mussels, the concentration was approximately 2 log lower than the exposition level after 24 h from the contamination, and then it decreased exponentially of 1 log every 24 h. Our findings suggest that in the experimental conditions tested A. butzleri is neither able to effectively grow in seawater nor bioaccumulate in mussels, at least in the free and cultivable form.

  12. Establishment and Preliminary Application of a PCR Detection Method for Simian Adenovirus%猴腺病毒(SAdV)PCR检测方法的建立及初步应用

    Institute of Scientific and Technical Information of China (English)

    张荣建; 贺争鸣

    2012-01-01

    目的 建立SAdV特异的PCR检测方法并研究实验猴群和猴源性生物制品中SAdV感染或污染情况.方法 比对分析多株SAdV序列,设计SAdV特异引物,优化PCR实验条件,建立的PCR方法经验证后检测实验猴群和猴源性生物制品,阳性产物测序并构建进化树.结果 经特异性和敏感性鉴定,在设计的5对引物中确定一对最佳引物,可以区分SAdV和MAD,ICH,CELO且可以检测到的最小DNA量为47.9 pg/mL.PCR方法检测实验猴群,阳性率49.2%,测序及进化分析表明,SAdV感染型别呈广泛基因多样性.主要分布在G亚属和以SAdV-49为代表的分支.结论经测序验证,PCR检测方法具有很好准确性,初步应用表明我国实验猴群中SAdV高度流行,应加强实验猴群及相关生物制品中SAdV的监测,避免人类感染SAdV的潜在风险.%Objective To establish a PCR detection method for simian adenovirus (SAdV) and study the SAdV infection status in monkeys. Methods To design a primer based on SAdV sequences and optimize the PCR experiment, test the method, to detect the virus in monkeys and vaccines, and sequenceing and constructing the phylogeny trees. Results A PCR detection method for SAdV was established, which could distinguish SAdV from MAD, ICH, CELO and was sensitive to 47. 9 pg/mL viral DNA. The results of this study showed a positive rate of 49. 2% and a large genetic diversity of simian adenoviruses in Chinese primate colony. Most of them belong to G subgroup and twig of SAdV-49. Conclusions This PCR detection method established in our laboratory has a good accuracy. We found a high prevalence of SAdV in Chinese primate colony. It is necessary to enhance detection and control for SAdV in monkeys and relevant biological products, and avoid potential risk of human infection.

  13. A preliminary experiment for the long-term regional reanalysis over Japan assimilating conventional observations with NHM-LETKF

    Science.gov (United States)

    Fukui, Shin; Iwasaki, Toshiki; Saito, Kazuo; Seko, Hiromu; Kunii, Masaru

    2016-04-01

    Several long-term global reanalyses have been produced by major operational centres and have contributed to the advance of weather and climate researches considerably. Although the horizontal resolutions of these global reanalyses are getting higher partly due to the development of computing technology, they are still too coarse to reproduce local circulations and precipitation realistically. To solve this problem, dynamical downscaling is often employed. However, the forcing from lateral boundaries only cannot necessarily control the inner fields especially in long-term dynamical downscaling. Regional reanalysis is expected to overcome the difficulty. To maintain the long-term consistency of the analysis quality, it is better to assimilate only the conventional observations that are available in long period. To confirm the effectiveness of the regional reanalysis, some assimilation experiments are performed. In the experiments, only conventional observations (SYNOP, SHIP, BUOY, TEMP, PILOT, TC-Bogus) are assimilated with the NHM-LETKF system, which consists of the nonhydrostatic model (NHM) of the Japan Meteorological Agency (JMA) and the local ensemble transform Kalman filter (LETKF). The horizontal resolution is 25 km and the domain covers Japan and its surroundings. Japanese 55-year reanalysis (JRA-55) is adopted as the initial and lateral boundary conditions for the NHM-LETKF forecast-analysis cycles. The ensemble size is 10. The experimental period is August 2014 as a representative of warm season for the region. The results are verified against the JMA's operational Meso-scale Analysis, which is produced with assimilating observation data including various remote sensing observations using a 4D-Var scheme, and compared with those of the simple dynamical downscaling experiment without data assimilation. Effects of implementation of lateral boundary perturbations derived from an EOF analysis of JRA-55 over the targeted domain are also examined. The comparison

  14. Biochemical, hydrological and mechanical behaviors of high food waste content MSW landfill: Preliminary findings from a large-scale experiment.

    Science.gov (United States)

    Zhan, Liang-Tong; Xu, Hui; Chen, Yun-Min; Lü, Fan; Lan, Ji-Wu; Shao, Li-Min; Lin, Wei-An; He, Pin-Jing

    2017-05-01

    A large-scale bioreactor experiment lasting for 2years was presented in this paper to investigate the biochemical, hydrological and mechanical behaviors of high food waste content (HFWC) MSW. The experimental cell was 5m in length, 5m in width and 7.5m in depth, filled with unprocessed HFWC-MSWs of 91.3 tons. In the experiment, a surcharge loading of 33.4kPa was applied on waste surface, mature leachate refilling and warm leachate recirculation were performed to improve the degradation process. In this paper, the measurements of leachate quantity, leachate level, leachate biochemistry, gas composition, waste temperature, earth pressure and waste settlement were presented, and the following observations were made: (1) 26.8m(3) leachate collected from the 91.3 tons HFWC-MSW within the first two months, being 96% of the total amount collected in one year. (2) The leachate level was 88% of the waste thickness after waste filling in a close system, and reached to over 100% after a surcharge loading of 33.4kPa. (3) The self-weight effective stress of waste was observed to be close to zero under the condition of high leachate mound. Leachate drawdown led to a gain of self-weight effective stress. (4) A rapid development of waste settlement took place within the first two months, with compression strains of 0.38-0.47, being over 95% of the strain recorded in one year. The compression strain tended to increase linearly with an increase of leachate draining rate during that two months. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. An interdisciplinary tillage erosion experiment: establishing a new field in grassland with reconstructed ard plough of the Bronze Age - Iron Age

    Science.gov (United States)

    Pavelka, Jan; Smetanová, Anna; Rejman, Jerzy; Kováčik, Peter

    2017-04-01

    Despite recognising the role of tillage erosion in landforms evolution, little research has documented its effects in prehistoric times. Herein, an interdisciplinary archaeological-geomorphological experiment with reconstructed tillage tools and management was conducted in order to measure tillage erosion when a new field in grasslands was established in the Bronze Age-Iron Age. Three wooden ards were reconstructed based on archaeological findings. They were tested in a cross-tillage experiment, consisting of a tillage pass perpendicular to the primary slope (6.5-9.7%), and a second tillage pass parallel to the primary slope of a convex-convex ridge with mowed grass (0.2 m high, vegetation cover >90%). The standard sole ard proved to be the most effective, with a mean tillage depth of 0.12 m, a mean tillage speed of 3.8 km h-1, and a mean distance between furrows of 0.20-0.25 m. Only 13% of the 264 tracers placed on 6 transects were displaced, and the mean tracers displacement parallel to the primary slope was 0.04 ± 0.17 m. Contour tillage perpendicular to primary slope created V or U shaped furrows with a mean depth of 0.1-0.12 m, a mean width of 0.05-0.1 m, and incision under the main root zone. Only soil in direct contact with the ard was displaced, with a mean translocation distance of 0.06 ± 0.2 m parallel and 0.06 ± 0.3 m perpendicular to the primary slope. During tillage parallel to slope, soil clods of 0.20 x 0.25 x 0.10 m were created and slightly disturbed or turned over one another. The tracers moved within the furrows and with the soil clods. Loose soil, resembling a seedbed, was not covered by soil clods. Mean displacement during the second pass was 0.03 ± 0.19 m parallel and 0.00 ± 0.15 m perpendicular to primary slope. The displacement from cross-tillage with a wooden ard in permanent grasslands was lower than many previously measured values of traditional animal-powered metal ploughs in permanent fields. No relationship between mean soil

  16. Preliminary approach to neutron instrument selection at ESS-Bilbao based on experience at ISIS molecular spectroscopy group

    Energy Technology Data Exchange (ETDEWEB)

    Vicente Bueno, J. P. de

    2014-07-01

    Collaborative efforts between the Neutronics and Target Design Group at the Instituto de Fusion Nuclear and the Molecular Spectroscopy Group at the ISIS Pulsed Neutron and Muon Source date back to 2012 in the context of the ESS-Bilbao project. The rationale for these joint activities was twofold, namely: to assess the realm of applicability of the low-energy neutron source proposed by ESS-Bilbao; and to explore instrument capabilities for pulsed-neutron techniques in the range 0.05-3 ms, a time range where ESS-Bilbao and ISIS could offer a significant degree of synergy and complementarity. As part of this collaboration, J.P. de Vicente has spent a three-month period within the ISIS Molecular Spectroscopy Group, to gain hands-on experience on the practical aspects of neutron-instrument design and the requisite neutron-transport simulations. Building upon these previous works, the primary aim of this report is to provide a self contained discussion of general criteria for instrument selection at ESS-Bilbao, the first accelerator-driven, low-energy neutron source designed in Spain. (Author)

  17. Childhood Traumatic Experiences, Dissociative Symptoms, and Dissociative Disorder Comorbidity Among Patients With Panic Disorder: A Preliminary Study.

    Science.gov (United States)

    Ural, Cenk; Belli, Hasan; Akbudak, Mahir; Tabo, Abdulkadir

    2015-01-01

    This study assessed childhood trauma history, dissociative symptoms, and dissociative disorder comorbidity in patients with panic disorder (PD). A total of 92 psychotropic drug-naive patients with PD, recruited from outpatient clinics in the psychiatry department of a Turkish hospital, were involved in the study. Participants were assessed using the Structured Clinical Interview for DSM-IV Dissociative Disorders (SCID-D), Dissociation Questionnaire, Panic and Agoraphobia Scale, Panic Disorder Severity Scale, and Childhood Trauma Questionnaire. Of the patients with PD, 18 (19%) had a comorbid dissociative disorder diagnosis on screening with the SCID-D. The most prevalent disorders were dissociative disorder not otherwise specified, dissociative amnesia, and depersonalization disorders. Patients with a high degree of dissociation symptoms and dissociative disorder comorbidity had more severe PD than those without (p dissociation and PD. Among all of the subscales, the strongest relationship was with childhood emotional abuse. Logistic regression analysis showed that emotional abuse and severity of PD were independently associated with dissociative disorder. In our study, a significant proportion of the patients with PD had concurrent diagnoses of dissociative disorder. We conclude that the predominance of PD symptoms at admission should not lead the clinician to overlook the underlying dissociative process and associated traumatic experiences among these patients.

  18. Preliminary results from the first integrated Magnetized Liner Inertial Fusion (MagLIF) experiments on the Z accelerator

    Science.gov (United States)

    Gomez, M. R.; Slutz, S. A.; Sefkow, A. B.; Harvey-Thompson, A. J.; Awe, T. J.; Cuneo, M. E.; Geissel, M.; Herrmann, M.; Jennings, C.; Lamppa, D.; Martin, M.; McBride, R. D.; Rovang, D. C.; Sinars, D.; Smith, I. C.

    2013-10-01

    Sandia National Laboratories' Z Machine provides a drive current of up to 27 MA with 100 ns risetime to a magnetically-driven load. Magnetized Liner Inertial Fusion (MagLIF) is the main focus of the inertial confinement fusion program on Z. The MagLIF concept uses an imploding metallic cylindrical liner to compress magnetized, pre-heated fusion fuel. Simulations indicate that fusion yields on the order of 100 kJ (5e16 DT neutrons) are achievable with a drive current of 27 MA in 100 ns, a laser preheat of 8 kJ in 8 ns, an applied axial B-field of 30 T, and deuterium-tritium fusion fuel. The first fully integrated MagLIF experiments are scheduled to be conducted on Z late summer 2013. These tests will utilize a drive current of 16 MA, a laser preheat of 2 kJ in 2 ns, an applied B-field of 10 T, and deuterium fuel. With these reduced parameters, simulations predict yields greater than 1e10 DD neutrons. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

  19. Preliminary study of a leak microstructure detector as a new single-electron counter for STARTRACK experiment

    Energy Technology Data Exchange (ETDEWEB)

    Ferretti, A. [INFN Laboratori Nazionali di Legnaro, viale dell' Universita 2, I-35020 Legnaro (Padova) (Italy)], E-mail: Alice.Ferretti@lnl.infn.it; De Nardo, L. [Physics Department and INFN Sezione di Padova, University of Padova, via Marzolo 8, I-35131 Padova (Italy); Lombardi, M. [INFN Laboratori Nazionali di Legnaro, viale dell' Universita 2, I-35020 Legnaro (Padova) (Italy)

    2009-02-11

    At Legnaro INFN Laboratories a track nanodosimetry experiment (STARTRACK) is installed in order to investigate the ion energy release in nanometric biological target. The nanodosimeter consists of a wall-less sensitive volume (SV), a series of collection electrodes and a single-electron detector, i.e. a drift column and a multi-step avalanche chamber (MSAC). To resolve temporally all the electrons collected from the SV, the possible replacement of the MSAC with a position sensitive gas counter has been investigated. In order to test if the leak microstructure (LM) counter can be used to detect single-electron in STARTRACK nanodosimeter, single-electron pulse-height spectra were measured in propane gas at low pressure (3 mbar). Experimental data show good prospects for this single step detector: LM detects single-electrons operating in proportional mode also at low pressure, the pulse-height spectra are well fitted by the theoretical Polya distribution, allowing to calculate the single-electron multiplication efficiency, which can reach a value of about 96%, quite similar to that of the MSAC detector.

  20. Implementation of fast macromolecular proton fraction mapping on 1.5 and 3 Tesla clinical MRI scanners: preliminary experience

    Science.gov (United States)

    Yarnykh, V.; Korostyshevskaya, A.

    2017-08-01

    Macromolecular proton fraction (MPF) is a biophysical parameter describing the amount of macromolecular protons involved into magnetization exchange with water protons in tissues. MPF represents a significant interest as a magnetic resonance imaging (MRI) biomarker of myelin for clinical applications. A recent fast MPF mapping method enabled clinical translation of MPF measurements due to time-efficient acquisition based on the single-point constrained fit algorithm. However, previous MPF mapping applications utilized only 3 Tesla MRI scanners and modified pulse sequences, which are not commonly available. This study aimed to test the feasibility of MPF mapping implementation on a 1.5 Tesla clinical scanner using standard manufacturer’s sequences and compare the performance of this method between 1.5 and 3 Tesla scanners. MPF mapping was implemented on 1.5 and 3 Tesla MRI units of one manufacturer with either optimized custom-written or standard product pulse sequences. Whole-brain three-dimensional MPF maps obtained from a single volunteer were compared between field strengths and implementation options. MPF maps demonstrated similar quality at both field strengths. MPF values in segmented brain tissues and specific anatomic regions appeared in close agreement. This experiment demonstrates the feasibility of fast MPF mapping using standard sequences on 1.5 T and 3 T clinical scanners.

  1. Continuous infusion of amphotericin B: preliminary experience at Faculdade de Medicina da Fundação ABC.

    Science.gov (United States)

    Uehara, Roberto Palermo; Sá, Victor Hugo Lara de; Koshimura, Erika Tae; Prudente, Fernanda Vilas Boas; Tucunduva, Luciana Tomanik Cardozo de Mello; Gonçalves, Marina Sahade; Samano, Eliana Sueco Tibana; del Giglio, Auro

    2005-09-01

    Intravenous amphotericin B deoxycholate (AmB-D) infusions, usually given over 4 hours, frequently induce nephrotoxicity and undesirable infusion-related side effects such as rigors and chills. There is evidence in the literature that the use of AmB-D in the form of continuous 24-hour infusion is less toxic than the usual four-hour infusion of this drug. Our objective was to evaluate the efficacy and safety of continuous infusion of AmB-D for the treatment of persistent fever in neutropenic patients with hematological malignancies after chemotherapy. Observational retrospective analysis of our experience with continuous infusion of AmB-D, at Faculdade de Medicina da Fundação ABC and Hospital Estadual Mário Covas in Santo André. From October 2003 to May 2004, 12 patients with hematological malignancies and chemotherapy-induced neutropenia received 13 cycles of continuous infusion of AmB-D. The median dose of AmB-D was 0.84 mg/kg/day (0.33 to 2.30 mg/kg/day). Concomitant use of nephrotoxic medications occurred in 92% of the cycles. Nephrotoxicity occurred in 30.76% of the cycles, hypokalemia in 16.67%, hepatotoxicity in 30% and adverse infusion-related events in 23%. All patients survived for at least seven days after starting continuous infusion of AmB-D, and clinical resolution occurred in 76% of the cycles. Continuous infusion of AmB-D can be used in our Institution as an alternative to the more toxic four-hour infusion of AmB-D and possibly also as an alternative to the more expensive liposomal formulations of the drug.

  2. Robot-Assisted Surgery for Mandibular Angle Split Osteotomy Using Augmented Reality: Preliminary Results on Clinical Animal Experiment.

    Science.gov (United States)

    Zhou, Chaozheng; Zhu, Ming; Shi, Yunyong; Lin, Li; Chai, Gang; Zhang, Yan; Xie, Le

    2017-07-19

    Mandibular angle split osteotomy (MASO) is a procedure widely used for prominent mandibular angles. However, conventional mandibular plastic surgery is invasive and high risk. It may induce postoperative neurosensory disturbance of the inferior alveolar nerve, fractures and infection due to the complexity of the anatomical structure and the narrow surgical field of view. The success rate of MASO surgery usually depends on the clinical experience and skills of the surgeon. To evaluate the performance of inexperienced plastic surgeons conducting this surgery, a self-developed and constructed robot system based on augmented reality is used. This robot system provides for sufficient accuracy and safety within the clinical environment. To evaluate the accuracy and safety of MASO surgery, an animal study using this robot was performed in the clinical room, and the results were then evaluated. Four osteotomy planes were successfully performed on two dogs; that is, twenty tunnels (each dog drilled on bilaterally) were drilled in the dogs' mandible bones. Errors at entrance and target points were 1.04 ± 0.19 and 1.22 ± 0.24 mm, respectively. The angular error between the planned and drilled tunnels was 6.69° ± 1.05°. None of the dogs experienced severe complications. Therefore, this technique can be regarded as a useful approach for training inexperienced plastic surgeons on the various aspects of plastic surgery. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

  3. Preliminary experience with air transfer of patients for rescue endovascular therapy after failure of intravenous tissue plasminogen activator.

    Science.gov (United States)

    Tsujimoto, Masanori; Yoshimura, Shinichi; Enomoto, Yukiko; Yamada, Noriaki; Matsumaru, Naoki; Kumada, Keisuke; Toyoda, Izumi; Ogura, Shinji; Iwama, Toru

    2015-01-01

    The present report describes our experience with air transfer of patients with acute ischemic stroke in whom intravenous tissue plasminogen activator (IV t-PA) failed for rescue endovascular therapy (EVT). Twenty-three consecutive patients in whom IV t-PA failed were transferred to our hospital for rescue EVT between February 2011 and April 2013. The amount of time required for transfer, distance, clinical outcomes, and complications were compared between patients transferred by ground (TG group; n = 17) and by air (TA group; n = 6). Computed tomography imaging on arrival revealed hemorrhagic transformation in 1 (5.9%) patient in the TG group, whereas none of the patients in the TA group developed any type of complication. The remaining 22 patients received rescue EVT. The elapsed time from the request call to arrival at our hospital did not significantly differ between the TG and TA groups (45.8 ± 4.9 min vs. 41.6 ± 2.3 min). However, the distance from the primary hospital to our institution was significantly longer for the TA group than for the TG group (38.8 ± 10.4 km vs. 13.5 ± 1.2 km, p = 0.001). The frequency of favorable outcomes (modified Rankin Scale 0-1 at 90 days after onset) in the TG and TA groups were 25.0% and 50.0%, respectively (p = 0.267). Air transfer for patients after IV t-PA failure allowed for more rapid delivery of patients over longer distances than ground transfer.

  4. Electron microscopic evaluation and fission product identification of irradiated TRISO coated particles from the AGR-1 experiment: A preliminary Study

    Energy Technology Data Exchange (ETDEWEB)

    I J van Rooyen; D E Janney; B D Miller; J L Riesterer; P A Demkowicz

    2012-10-01

    ABSTRACT Post-irradiation examination of coated particle fuel from the AGR-1 experiment is in progress at Idaho National Laboratory and Oak Ridge National Laboratory. In this presentation a brief summary of results from characterization of microstructures in the coating layers of selected irradiated fuel particles with burnup of 11.3% and 19.3% FIMA will be given. The main objective of the characterization were to study irradiation effects, fuel kernel porosity, layer debonding, layer degradation or corrosion, fission-product precipitation, grain sizes, and transport of fission products from the kernels across the TRISO layers. Characterization techniques such as scanning electron microscopy, transmission electron microscopy, energy dispersive spectroscopy, and wavelength dispersive spectroscopy were used. A new approach to microscopic quantification of fission-product precipitates is also briefly demonstrated. The characterization emphasized fission-product precipitates in the SiC-IPyC interface, SiC layer and the fuel-buffer interlayer, and provided significant new insights into mechanisms of fission-product transport. Although Pd-rich precipitates were identified at the SiC-IPyC interlayer, no significant SiC-layer thinning was observed for the particles investigated. Characterization of these precipitates highlighted the difficulty of measuring low concentration Ag in precipitates with significantly higher concentrations of contain Pd and U. Different approaches to resolving this problem are discussed. Possible microstructural differences between particles with high and low releases of Ag particles are also briefly discussed, and an initial hypothesis is provided to explain fission-product precipitate compositions and locations. No SiC phase transformations or debonding of the SiC-IPyC interlayer as a result of irradiation were observed. Lessons learned from the post-irradiation examination are described and future actions are recommended.

  5. Turbo STIR magnetic resonance imaging as a whole-body screening tool for metastases in patients with breast carcinoma: preliminary clinical experience.

    Science.gov (United States)

    Walker, R; Kessar, P; Blanchard, R; Dimasi, M; Harper, K; DeCarvalho, V; Yucel, E K; Patriquin, L; Eustace, S

    2000-04-01

    This study was undertaken to assess the utility of whole-body turbo short tau inversion recovery (STIR) magnetic resonance imaging (MRI) to detect metastases to liver, brain, and bone as a single examination in women with breast cancer. Seventeen patients with biopsy-proven breast cancer and suspected metastatic disease attending over a 12-month period referred for both conventional imaging and whole-body MRI were included in the study. Three patients were found to be free of metastases at both conventional and MR imaging. Appendicular or axial skeletal metastases were identified in 11 of 17 patients, with correlation between findings at whole-body MRI and scintigraphy in 15 of the 17 patients. Five patients had evidence of hepatic metastases on whole-body MRI, of which metastases were identified in only three patients at CT despite contrast enhancement. Four patients had brain abnormalities (metastases in three patients, meningioma in one patient) detected on both whole-body and dedicated brain MRI. Preliminary clinical experience suggests that turbo STIR whole-body MRI may represent a convenient and cost-effective method of total body screening for metastases in patients with breast carcinoma.

  6. Skull Bone Defects Reconstruction with Custom-Made Titanium Graft shaped with Electron Beam Melting Technology: Preliminary Experience in a Series of Ten Patients.

    Science.gov (United States)

    Francaviglia, Natale; Maugeri, Rosario; Odierna Contino, Antonino; Meli, Francesco; Fiorenza, Vito; Costantino, Gabriele; Giammalva, Roberto Giuseppe; Iacopino, Domenico Gerardo

    2017-01-01

    Cranioplasty represents a challenge in neurosurgery. Its goal is not only plastic reconstruction of the skull but also to restore and preserve cranial function, to improve cerebral hemodynamics, and to provide mechanical protection of the neural structures. The ideal material for the reconstructive procedures and the surgical timing are still controversial. Many alloplastic materials are available for performing cranioplasty and among these, titanium still represents a widely proven and accepted choice. The aim of our study was to present our preliminary experience with a "custom-made" cranioplasty, using electron beam melting (EBM) technology, in a series of ten patients. EBM is a new sintering method for shaping titanium powder directly in three-dimensional (3D) implants. To the best of our knowledge this is the first report of a skull reconstruction performed by this technique. In a 1-year follow-up no postoperative complications have been observed and good clinical and esthetic outcomes were achieved. Costs higher than those for other types of titanium mesh, a longer production process, and the greater expertise needed for this technique are compensated by the achievement of most complex skull reconstructions with a shorter operative time.

  7. Preliminary experience in adult-to-adult living donor liver transplantation in a single center in China

    Institute of Scientific and Technical Information of China (English)

    YAN Lunan; CHEN Zheyu; LIU Jiangwen; WU Hong; LI Bo; ZENG Yong; WEN Tianfu; ZHAO Jichun; WANG Wentao; YANG Jiayin; XU Mingqing; MA Yukui

    2007-01-01

    The aim of this paper is to report the authors'experience in performing adult-to-adult living donor liver transplantation (LDLT)by using a modified technique in using grafts of the right lobe of the liver.From January 2002 to September 2006,56 adult patients underwent LDLT using right lobe grafts at the Wlest China Hospital.Sichuan University Medical School,China.All patients underwent a modified operation designed to improve the reconstruction of the right hepatic vein (RHV)and the tributariers of the middle hepatic vein(MHV)by interposing a vessel graft,and by anastomosing the hepatic arteries and bile ducts.There were no severe complications or deaths in all donors.Fifty-two (92.8%) recipients survived the operations.Among the 56 recipients,complications were seen in 15 recipients(26.8%),including hepatic vein stricture(one case),small-for-size syndrome(one case),hepatic artery thrombosis(two cases),intestinal bleeding (one case),bile leakage(two cases),left subphrenic abscess (one case),renal failure(two cases)and pulmonary infection (five cases).Within three months after transplantation,four recipients(7.1 4%)died due to smallfor-size syndrome(one case),renal failure(one case)and multiple organ failure(two cases).All patients underwent direct anastomoses of the RHV and the inferior vena cava (IVC),and in 23 cases,reconstruction of the right inferior hepatic vein was also done.In 24 patients,the reconstruction of the tributaries of the MHV was also done by interposing a vessel graft to provide sufficient venous outflow.Trifurcation of the portal vein was seen in nine cases.Thus,veno-plasty or separate anastomoses were performed.The graft and recipient body weight ratios(GRWR)were between 0.72%and 1.43%,and in three cases it was<0.8%.The graft weight to recipient standard liver volume ratios (GV/SLV) were between 31.86%and 71.68%.among which four cases had<40%.No "small-for-size syndrome"occurred.With modification of the surgical technique,especially in the

  8. Regional Aerosol Forcing over India: Preliminary Results from the South West Asian Aerosol-Monsoon Interactions (SWAAMI) Aircraft Experiment

    Science.gov (United States)

    Morgan, W.; Brooks, J.; Fox, C.; Haslett, S.; Liu, D.; Kompalli, S. K.; Pathak, H.; Manoj, M. R.; Allan, J. D.; Haywood, J. M.; Highwood, E.; Langridge, J.; Nanjundaiah, R. S.; Krishnamoorthy, K.; Babu, S. S.; Satheesh, S. K.; Turner, A. G.; Coe, H.

    2016-12-01

    Aerosol particles from multiple sources across the Indian subcontinent build up to form a dense and extensive haze across the region in advance of the monsoon. These aerosols are thought to perturb the regional radiative balance and hydrological cycle, which may have a significant impact on the monsoon circulation, as well as influencing the associated cloud and rainfall of the system. However the nature and magnitude of such impacts are poorly understood or constrained. Major uncertainties relevant to the regional aerosol burden include its vertical distribution, the relative contribution of different pollution sources and natural emissions and the role of absorbing aerosol species (black carbon and mineral dust). The South West Asian Aerosol-Monsoon Interactions (SWAAMI) project sought to address these major uncertainties by conducting an airborne experiment during June/July 2016 on-board the UK Facility for Airborne Atmospheric Measurement (FAAM) BAe-146 research aircraft. Based out of Lucknow in the), The aircraft conducted multiple flights from Lucknow in the heart of the Indo-Gangetic Plain (IGP) in advance of the monsoon and during the onset phase. The spatial and vertical distribution of aerosol was evaluated across northern India, encompassing drier desert-like regions to the west, heavily populated urban and industrial centres over the IGP and air masses in outflow regions to the south-east towards the Bay of Bengal. Principal measurements included aerosol chemical composition using an Aerodyne Aerosol Mass Spectrometer and a DMT Single Particle Soot Photometer, alongside a Leosphere backscatter LIDAR. Sulphate was a major contributor to the aerosol burden across India, while the organic aerosol was elevated and more dominant over the most polluted regions of the IGP. Substantial aerosol concentrations were frequently observed up to altitudes of approximately 6km, with notable changes in aerosol chemical and physical properties when comparing different

  9. Rayleigh-wave imaging of upper-mantle shear velocities beneath the Malawi Rift; Preliminary results from the SEGMeNT experiment

    Science.gov (United States)

    Accardo, N. J.; Gaherty, J. B.; Shillington, D. J.; Nyblade, A.; Ebinger, C. J.; Mbogoni, G. J.; Chindandali, P. R. N.; Mulibo, G. D.; Ferdinand-Wambura, R.; Kamihanda, G.

    2015-12-01

    The Malawi Rift (MR) is an immature rift located at the southern tip of the Western branch of the East African Rift System (EARS). Pronounced border faults and tectonic segmentation are seen within the upper crust. Surface volcanism in the region is limited to the Rungwe volcanic province located north of Lake Malawi (Nyasa). However, the distribution of extension and magma at depth in the crust and mantle lithosphere is unknown. As the Western Rift of the EARS is largely magma-poor except for discrete volcanic provinces, the MR presents the ideal location to elucidate the role of magmatism in early-stage rifting and the manifestation of segmentation at depth. This study investigates the shear velocity of the crust and mantle lithosphere beneath the MR to constrain the thermal structure, the amount of total crustal and lithospheric thinning, and the presence and distribution of magmatism beneath the rift. Utilizing 55 stations from the SEGMeNT (Study of Extension and maGmatism in Malawi aNd Tanzania) passive-source seismic experiment operating in Malawi and Tanzania, we employed a multi-channel cross-correlation algorithm to obtain inter-station phase and amplitude information from Rayleigh wave observations between 20 and 80 s period. We retrieve estimates of phase velocity between 9-20 s period from ambient noise cross-correlograms in the frequency domain via Aki's formula. We invert phase velocity measurements to obtain estimates of shear velocity (Vs) between 50-200 km depth. Preliminary results reveal a striking low-velocity zone (LVZ) beneath the Rungwe volcanic province with Vs ~4.2-4.3 km/s in the uppermost mantle. Low velocities extend along the entire strike of Lake Malawi and to the west where a faster velocity lid (~4.5 km/s) is imaged. These preliminary results will be extended by incorporating broadband data from seven "lake"-bottom seismometers (LBS) to be retrieved from Lake Malawi in October of this year. The crust and mantle modeling will be

  10. Establishing a population-based patient-reported outcomes study (PROMs) using national cancer registries across two jurisdictions: the Prostate Cancer Treatment, your experience (PiCTure) study

    Science.gov (United States)

    Drummond, F J; Kinnear, H; Donnelly, C; O'Leary, E; O'Brien, K; Burns, R M; Gavin, A; Sharp, L

    2015-01-01

    Objective To establish an international patient-reported outcomes (PROMs) study among prostate cancer survivors, up to 18 years postdiagnosis, in two countries with different healthcare systems and ethical frameworks. Design A cross-sectional, postal survey of prostate cancer survivors sampled and recruited via two population-based cancer registries. Healthcare professionals (HCPs) evaluated patients for eligibility to participate. Questionnaires contained validated instruments to assess health-related quality of life and psychological well-being, including QLQ-C30, QLQ-PR25, EQ-5D-5L, 21-question Depression, Anxiety and Stress Scale (DASS-21) and the Decisional Regret Scale. Setting Republic of Ireland (RoI) and Northern Ireland (NI). Primary outcome measures Registration completeness, predictors of eligibility and response, data missingness, unweighted and weighted PROMs. Results Prostate cancer registration was 80% (95% CI 75% to 84%) and 91% (95% CI 89% to 93%) complete 2 years postdiagnosis in NI and RoI, respectively. Of 12 322 survivors sampled from registries, 53% (n=6559) were classified as eligible following HCP screening. In the multivariate analysis, significant predictors of eligibility were: being ≤59 years of age at diagnosis (p<0.001), short-term survivor (<5 years postdiagnosis; p<0.001) and from RoI (p<0.001). 3348 completed the questionnaire, yielding a 54% adjusted response rate. 13% of men or their families called the study freephone with queries for assistance with questionnaire completion or to talk about their experience. Significant predictors of response in multivariate analysis were: being ≤59 years at diagnosis (p<0.001) and from RoI (p=0.016). Mean number of missing questions in validated instruments ranged from 0.12 (SD 0.71; EQ-5D-5L) to 3.72 (SD 6.30; QLQ-PR25). Weighted and unweighted mean EQ-5D-5L, QLQ-C30 and QLQ-PR25 scores were similar, as were the weighted and unweighted prevalences of depression, anxiety and

  11. 76 FR 52945 - Chlorpyrifos Registration Review; Preliminary Human Health Risk Assessment; Extension of Comment...

    Science.gov (United States)

    2011-08-24

    ... AGENCY Chlorpyrifos Registration Review; Preliminary Human Health Risk Assessment; Extension of Comment... availability of the chlorpyrifos registration review; preliminary human health risk assessment. This document... for the chlorpyrifos reregistration review, preliminary human health risk assessment, established in...

  12. Virtual laryngoscopy-preliminary experience

    Energy Technology Data Exchange (ETDEWEB)

    Byrne, A.T. [Departments of Radiology, Adelaide and Meath Hospital, Dublin 24 (Ireland); Walshe, P. [Departments of Otolaryngology, Adelaide and Meath Hospital, Dublin 24 (Ireland); McShane, D. [Departments of Otolaryngology, Adelaide and Meath Hospital, Dublin 24 (Ireland); Hamilton, S. [Departments of Radiology, Adelaide and Meath Hospital, Dublin 24 (Ireland)]. E-mail: samuel.hamilton@amnch.ie

    2005-10-01

    Purpose: Computed tomographic virtual laryngoscopy is a non-invasive radiological technique that allows visualisation of intra-luminal surfaces by three-dimensional reconstruction of air/soft tissue interfaces. It is particularly useful when the patient cannot tolerate clinical examination, when infection, neoplasm or congenital defects compromise the lumen and for assessment of the sub-glottic region. We have performed virtual laryngoscopy on patients referred because of upper airway symptoms, and compared the findings with those at conventional laryngoscopy. Materials and methods: Axial scans were obtained using a Toshiba Xpress helical scanner. Virtual laryngoscopy was then performed on a workstation using Toshiba 'Fly-thru' software and was completed within 5 min. Results: Pathology included vocal cord nodules, laryngeal cysts, Reinke's oedema, laryngeal neoplasms and leukoplakia. Conclusions: Virtual laryngoscopy displays anatomical detail comparable to conventional endoscopy. Impassable obstructions are no hindrance and all viewing directions are possible. It is especially useful for providing views of the larynx from below.

  13. Tidal peritoneal dialysis: preliminary experience.

    Science.gov (United States)

    Flanigan, M J; Doyle, C; Lim, V S; Ullrich, G

    1992-01-01

    To determine the feasibility of home tidal peritoneal dialysis (TPD) and to assess whether eight hours of TPD can achieve uremia control and urea removal equal to that of continuous cycling peritoneal dialysis (CCPD). An open enrollment pilot study. The Home Dialysis Training Center of the University of Iowa Hospitals and Clinics, a tertiary care teaching hospital. Nine patients experienced with CCPD and living 80 km to 280 km from the dialysis center began TPD, because they wished to decrease their dialysis time. Following baseline measurements, each patient was taught to perform TPD. TPD consisted of an initial fill volume of 40 mL/kg, a residual volume approximately 20 mL/kg, and tidal exchanges of 10 to 20 mL/kg to achieve the desired hourly flow rate. Clinic assessments took place every four to six weeks, and prescriptions were subsequently altered to attain urea removal equal to that of CCPD. Patient interviews were used to determine TPD acceptance. Prior to each clinic visit, dialysate effluent volume and dialysis duration were recorded, and a sterile sample of the effluent was obtained for urea, creatinine, and total nitrogen measurement. Urea and creatinine clearances increased with dialysate flow. Dialysate nonurea nitrogen was 3.0 +/- 0.2 mmol/kg/D and changed minimally with increasing dialysate volumes. Eight hours of TPD (initial fill: 40 mL/kg; residual volume: 20 mL/kg; tidal inflow: 20 mL/kg) with hourly tidal flow exceeding 40 mL/kg/hr and no daytime volume achieved urea removal equal to that of the patient's prior CCPD prescription. TPD can provide dialysis equal to that of CCPD within a shorter amount of time (eight vs ten hours), but uses a greater volume of dialysate (16.0 L for TPD vs 9.5 L for CCPD).

  14. A new class of electrodes of 'intermediate invasiveness': preliminary experience with epidural pegs and foramen ovale electrodes in the mapping of seizure foci.

    Science.gov (United States)

    Awad, I A; Assirati, J A; Burgess, R; Barnett, G H; Luders, H

    1991-09-01

    Non-invasive electroencephalographic (EEG) recording with scalp and sphenoidal leads is often insensitive to precise localization of ictal onset, and can be distorted by skull defects and underlying lesions or deformities of the brain. We present preliminary experience with epidural pegs and foramen ovale electrodes used in 30 cases of intractable partial epilepsy where non-invasive EEG did not define a zone of epileptogenesis with sufficient precision to recommend resection, or to dictate precise placement of depth electrodes or subdural girds. Custom designed mushroom shaped peg electrodes were implanted via 4.5 mm twist-drill skull holes for epidural recording from cortical areas of suspected epileptogenesis. Foramen ovale electrodes (flexible 3-contact leads) were introduced via percutaneous puncture of Meckel's cave cistern for recording from mesiotemporal regions. Chronic recording was performed for 4 to 26 days (mean 9.2 days). There were no serious complications and signal quality was excellent in every electrode. Based on interictal and ictal records, resective surgery was performed in 8 cases, more focused further invasive recording was recommended in 15 cases (with subsequent resective surgery), and surgical options were excluded in 7 cases. It is concluded that these electrodes of 'intermediate invasiveness' represent a safe and effective tool in the armamentarium for mapping complicated or elusive epileptic foci. They can be used in lieu of, in addition to, or prior to more invasive measures. Their greatest advantage lies in their relative safety and ability to survey extensive zones of suspected epileptogenesis so as to guide and focus further mapping and surgical intervention.

  15. Preliminary designs: passive solar manufactured housing. Technical status report

    Energy Technology Data Exchange (ETDEWEB)

    1980-05-12

    The criteria established to guide the development of the preliminary designs are listed. Three preliminary designs incorporating direct gain and/or sunspace are presented. Costs, drawings, and supporting calculations are included. (MHR)

  16. Sentinel Node Mapping Using Indocyanine Green and Near-infrared Fluorescence Imaging Technology for Uterine Malignancies: Preliminary Experience With the Da Vinci Xi System.

    Science.gov (United States)

    Siesto, Gabriele; Romano, Fabrizio; Fiamengo, Barbara; Vitobello, Domenico

    2016-01-01

    Sentinel lymph node (SLN) mapping has emerged as the new frontier for the surgical staging of apparently early-stage cervical and endometrial cancer. Different colorimetric and radioactive tracers, alone and in combination, have been proposed with encouraging results. Fluorometric mapping using indocyanine green (ICG) appears to be a suitable and attractive alternative to provide reliable staging [1-4]. In this video, we present the technique of SLN mapping in 2 cases (1 endometrial and 1 cervical cancer, respectively) using ICG and the near-infrared technology provided by the newest Da Vinci Xi robotic system (Intuitive Surgical Inc., Sunnyvale, CA). Together we report the results of our preliminary experience on the first 20 cases performed. The new robotic Da Vinci Xi system was available at our institution since May 2015. Upon institutional review board/ethical committee approval, all consecutive patients with early-stage endometrial and cervical cancer who were judged suitable for robotic surgery have been enrolled for SLN mapping with ICG. We adopted the Memorial Sloan Kettering Cancer Center SLN algorithm; the tracer was delivered into the cervix in all cases. Four milliliters (1.25 mg/mL) of ICG was injected divided into the 3- and 9-o'clock positions of the cervix alone, with 1 mL deep into the stroma and 1 mL submucosally at the skin incision. Sentinel lymph nodes were examined with a protocol including both ultrastaging with immunohistochemistry [3] and 1-step nucleic acid amplification assay [5,6] under a parallel protocol of study. During the study period, 20 cases were managed; 14 and 6 patients had endometrial and cervical cancer, respectively. SLN was detected in all cases (20/20, 100%). Bilateral SLNs were detected in 17 of 20 (85.0%) cases. Based on preoperative and intraoperative findings, 13 (65.0%) patients received systematic pelvic lymphadenectomy after SLN mapping. Three (15.0%) patients had microscopic nodal metastases on SLN. No

  17. Construction of subjectivities through a non-formal educative experience in Contexts of Confinement: the Case of the National University of Villa María in the Penitentiary Establishment Nº 5, Province of Córdoba

    Directory of Open Access Journals (Sweden)

    Carla Fernanda Avendaño Manelli

    2016-02-01

    After this experience, the critical analysis of the relationship between communication, education and prison, allowed us to adapt this project to an investigation project. Its aim is to understand the complexity of the processes of construction of prisoners’ subjectivities, through the common spaces of communication and education in the Penitentiary Establishment Nº 5 of Villa Maria.

  18. Establishment of a Comprehensive List of Candidate Antiaging Medicinal Herb Used in Korean Medicine by Text Mining of the Classical Korean Medical Literature, “Dongeuibogam,” and Preliminary Evaluation of the Antiaging Effects of These Herbs

    Directory of Open Access Journals (Sweden)

    Moo Jin Choi

    2015-01-01

    Full Text Available The major objectives of this study were to provide a list of candidate antiaging medicinal herbs that have been widely utilized in Korean medicine and to organize preliminary data for the benefit of experimental and clinical researchers to develop new drug therapies by analyzing previous studies. “Dongeuibogam,” a representative source of the Korean medicine literature, was selected to investigate candidate antiaging medicinal herbs and to identify appropriate terms that describe the specific antiaging effects that these herbs are predicted to elicit. In addition, we aimed to review previous studies that referenced the selected candidate antiaging medicinal herbs. From our chosen source, “Dongeuibogam,” we were able to screen 102 terms describing antiaging effects, which were further classified into 11 subtypes. Ninety-seven candidate antiaging medicinal herbs were selected using the criterion that their antiaging effects were described using the same terms as those employed in “Dongeuibogam.” These candidates were classified into 11 subtypes. Of the 97 candidate antiaging medicinal herbs selected, 47 are widely used by Korean medical doctors in Korea and were selected for further analysis of their antiaging effects. Overall, we found an average of 7.7 previous studies per candidate herb that described their antiaging effects.

  19. 高寒地区人工草地建植技术与效益初步分析%Preliminary Analysis on Establishing Technology and Benefits of Artificial Grassland in the Alpine Areas

    Institute of Scientific and Technical Information of China (English)

    王万林; 王建华; 阿不都卡哈尔; 李超; 安沙舟

    2011-01-01

    本文通过在新疆昭苏马场高寒地区进行人工草地建植技术的试验研究,采用禾草与豆科草混播的方法,以大麦地套种人工混播草地模式进行两次播种。,结果表明:建植人工草地套种大麦模式,第一年牧草生长良好、牧草可以安全越冬,禾草出苗率可以达到80%,豆科出苗率达到85%,人工草地建植成本为3385.95元/ha,大麦产值为5184元/ha,套种效益明显,第一年即可收回成本的153.1%。建植二、三年后,草地牧草产草量可相对稳定,达到建植生产需求目的,其在高寒地区建植人工草地是可行的,在畜牧业生产过程中可以推广应用。%Establishing technology of artificial grassland was studied in alpine areas of Zhaosu Horse Farm. Perennial grasses and Leguminous grass were selected to sow in the mixture way and were sew two times by the model of inter-planting of barley and artificial grassland mixture sowing. The results showed that: In the model of inter-planting barley in artificial grassland, forage grew well in the first year and could safely get through winter rest. Germination rate of perennial grasses and Leguminous grass could respectively reach 80% and 85%. Establishing cost of artificial grassland was 225.7 yuan RMB/667m2, and output value of barley was 345.6 yuan RMB/667m2. Inter-planting effect was remarkable, so the cost of 153.1% could be obtained in the first year. After two or three years of establishing artificial grassland, grass yield of pasture was relatively stable and could get to the production requirement of establishing artificial grassland. Establishing artificial grassland can apply to both alpine areas and the production process of animal husbandry.

  20. First experience with a new biomedical engineering program in Slovenia established following the TEMPUS IV CRH-BME joint project guidelines.

    Science.gov (United States)

    Jarm, Tomaz; Miklavcic, Damijan

    2014-01-01

    A new study program of biomedical engineering was recently established at Faculty of Electrical Engineering, University of Ljubljana, Slovenia. It is based on the long-lasting tradition of education in the field of BME at the host institution and is built on the BME areas in which the research groups of the Faculty of Electrical Engineering have been traditionally successful. The program was prepared in accordance with the recommendations of the TEMPUS IV CRH-BME Project consortium.

  1. STUDY EXPERIENCE AND ESTABLISHMENT OF METASTATIC RABBIT MODEL WITH VX-2 CARCINOMA IN LIVER%兔肝VX2移植癌模型的建立

    Institute of Scientific and Technical Information of China (English)

    陈利平; 文天夫

    2011-01-01

    [目的]制作VX-2兔肝移植癌模型.[方法]新西兰白兔10只,采用VX-2瘤株动物自身接种传代.采用瘤组织块包埋法,均接种于肝左叶.[结果]2周后均顺利成瘤,该瘤在肝组织中呈浸润式生长.[结论]成功建立了兔VX-2移植性肝癌模型,为肝癌治疗的基础及临床研究提供了成熟的大型实验动物肝癌模型.%[Objective]To establish a metastatic rabbit VX-2 liver tumor model.[Methods]10 New-Zealand white rabbits were inoculated with VX-2 carcinoma in the left lobe of the liver by implantation.[Results]The tumor was successfully established two weeks later.The tumor grew in the liver tissue and infiltrated into the normal liver tissue.[Conclusion]It is successful to establish a modified metastatic rabbit VX-2 liver carcinma model, and it makes it possible to gain a reliable mature large animal model of tumor for the basic and clinical study of therapy of liver carcinoma.

  2. Preliminary results of simulation of hypo magnetic conditions and variations in energetic range of cosmic rays in ground-based experiments on plant objects

    Science.gov (United States)

    Belisheva, Natalia; Petrashova, Dina; Shchegolev, Boris

    The most dangerous for the astronauts and cosmonauts are the cosmic rays and drastic decrease of the tension of geomagnetic field (GMF) on the Earth orbit and in the open space. The tension in the interplanetary magnetic field is 10 nT, whereas the tension of GMF is 10 (4) nT on the Earth surface. We carried out the preliminary experiments for study the effects of hypo magnetic conditions and variations in energetic range of cosmic rays (CR) on the plant objects (Vigna radiata, Phaseolus vulgaris, Allium cepa and A. fistulosum, Cucumis sativis). GMF was weakened by using special shielding chamber made on the basis of the amorphous alloy magnetic material. The camera is able to weaken the GMF from 48 μT till 0.192 μT. Modulation of the energetic range of the neutron component of secondary CR was performed with using of the shielding by graphite and by paraffin. The influence of hypo magnetic field and the neutron intensity were studied on the germination of seeds, the growth, the length and the side branches of the roots in the experimental samples. We found that the sensitivity to the hypo magnetic field and to the variations in energetic range of neutrons can vary from object to object. For instance, exposure of the hypo magnetic field on black bean and mung bean stimulated the growth of the roots while do not affect on the white bean. Likewise sensitivity of Phaseolus vulgaris (black and white bean) and Vigna radiata (mung bean) to exposure of nucleon component of cosmic rays on the Earth's surface are differed. It was found that modification of energetic range of CR by using graphite shielding leads to a change in sign of correlation between the length of roots in all experimental samples and the nucleon component of CR compared with the control samples. This is evidence that physiology of biological objects significantly are modified in hypo magnetic environment, as well as under exposure of the CR in different energetic ranges during the space flights. Our

  3. Preliminary Clinical Experience of trans-1-Amino-3-(18F-fluorocyclobutanecarboxylic Acid (anti-(18F-FACBC PET/CT Imaging in Prostate Cancer Patients

    Directory of Open Access Journals (Sweden)

    Kalevi Kairemo

    2014-01-01

    Full Text Available Background. In this retrospective analysis we assessed the role of [18F]-FACBC-PET/CT in the prostatic cancer staging. Procedure. 30 first [18F]-FACBC-PET/CT images of 26 patients (68.1 ± 5.8 years were analyzed. PET/CT findings were compared with PSA concentrations, with PSA doubling times (PDT, and with correlative imaging. Results. On 16 [18F]-FACBC (53.3% scans, 58 metabolically active lesions were found. 12 (20.7% lesions corresponding to the local relapse were found in prostate/prostate bed and seminal vesicles, 9 (15.5% lesions were located in regional lymph nodes, 10 (17.2% were located in distal lymph nodes, and 26 (44.8% metabolically active lesions were found in the skeleton. In one case, focal uptake was found in the brain, confirmed further on MRI as meningioma. The mean S-PSA level in patients with positive [18F]-FACBC findings was 9.5 ± 16.9 μg/L (0.54–69 μg/L and in patients with negative [18F]-FACBC findings was 1.96 ± 1.87 μg/L (0.11–5.9 μg/L, but the difference was not statistically significant. However, the PSA doubling time (PDT in patients with positive findings was significantly shorter than PDT in patients with negative findings: 3.25 ± 2.09 months (0.3–6 months versus 31.2 ± 22.02 months (8–84 months, P<0.0001. There was a strong positive correlation between PSA value and number of metabolically active lesions (R=0.74 and a negative correlation between PDT and number of metabolically active lesions (R=-0.56. There was a weak negative correlation between PDT and SUVmax⁡ (R=-0.30. Conclusion. According to our preliminary clinical experience, [18F]-FACBC-PET may play a role in in vivo restaging of an active prostate cancer, especially in patients with a short S-PSA doubling time.

  4. 建立护士绩效考核体系的实践效果%Practical experience of establishing nurses′ performance appraisal index system

    Institute of Scientific and Technical Information of China (English)

    林花丽

    2015-01-01

    Objective:Establishing nurses′ performance appraisal index system and evaluating the result of performance appraisal, in order to provide a sci-entific basis for reasonable payment distribution,human resource and nursing quality management. Methods:Nurses′ performance appraisal index system was established based on post management,ladder management,work quantity,work quanlity and nurse career planning,questionnaire made by ourself was col-lected and the result of performance appraisal was evaluated. Results:After establishing nurses′ performance appraisal index system,nurse performance salary was paid according to their work quatity and quality,satisfaction rate of nursing managementers,nurses and patients was improved. Conclusion:By establis-hing nurses′ performance appraisal index system,it is positive to form excellent management guide,improve clinical nursing quality,arouse nurses′ enthusi-asm and improve the patient′s satisfaction rate.%目的::通过建立护士工作绩效考核体系,为合理分配薪酬、人力资源管理、护理质量管理提供科学依据。方法:以岗位管理、层级管理、工作量、工作质量、护士职业规划等方面为切入点建立护理绩效考核体系,使用自制调查问卷收集资料,并对考核结果进行分析。结果:绩效考核体系建立后,护士绩效工资体现多劳多得、优绩优酬,护理管理者满意度、护士满意度、患者满意度均有提高。结论:建立行之有效的护士绩效考核体系,有利于形成良好的管理导向,提高临床护理质量,调动护理人员的积极性。

  5. 白喉类毒素酶联免疫检测法的建立及初步应用%Establishment and preliminary application of a quantitative ELISA in detection of diphtheria toxoid

    Institute of Scientific and Technical Information of China (English)

    张霖阳; 杨冰; 王珣; 张娜; 赵俊; 王玲

    2016-01-01

    目的:建立测定吸附无细胞百白破联合疫苗中白喉类毒素酶联免疫检测( ELISA)方法,并进行验证及初步应用。方法以高效价兔抗DT多克隆抗体和相应酶标抗体建立双抗体夹心ELISA法,确定线性范围同时验证该方法的重复性和特异性等确定检测限度,并初步应用。结果 DT含量在0~0.0160 Lf/mL范围内反应曲线线性关系良好(r >0.99)。该方法与破伤风类毒素(Tetanus toxoid,TT)、百日咳毒素(Pertussis toxin,PT)、百日咳丝状血凝素( Filamantous hemagglutinin,FHA)与黏着素( Pertactin,Prn)无明显交叉反应,重复性好、特异性较强,精密度及准确度验证均符合常规质控要求,通过验证确定的准确检测范围为0.0008~0.0160 Lf/mL;检测限度为0.0008 Lf/mL。该方法对DT抗原进行了吸附率的检测,同时检测了10批白喉类毒素原液与《中华人民共和国药典》三部2010年版规定的絮状单位检测方法进行对比,变异系数低于20%。结论建立了白喉类毒素双抗体夹心 ELISA检测方法,为吸附无细胞百白破联合疫苗生产过程中白喉类毒素含量的质量控制提供了有效技术手段。%Objective To develop and preliminary application a double antibody sandwich ELISA in quantitative determi-nation of diphtheria toxoid ( DT ) in DTaP ( Diphtheria, tetanus and acellular pertussis combined vaccine, adsorbed ) . Methods The DT polyclonal antibodies with a high potency were obtained by using DT immunized rabbit antisera, and the detective enzyme labeled antibody as signal in order to develop a double antibody sandwich ELISA in quantitative determi-nation of DT in DTap. The linear range was determined, the repeatability and specificity for the ELISA were verified, and detection limit was determined as well. The preliminary application of the ELISA was performed. Results The best lineari-ty of dose-response curve was found in a range of 0-0. 0160 Lf/mL(r >0. 99). The tested result was

  6. A dependence of a sports result on physical development, morphofunctional and special strength preparedness data of weightlifters at the stage of preliminary basic training

    OpenAIRE

    Півень, Олександр; Дорофєєва, Тетяна

    2017-01-01

    Oleksandr Piven & Tetiana Dorofieieva Purpose: establishing the nature of the relationship between the sporting result of weightlifters 15–17 years and the level of their special physical and morphofunctional preparedness at the stage of preliminary basic training. Material & Methods: 30 athletes of the group of preliminary basic training of the second year of training were involved in the experiment. The study was conducted on the basis of the department of weightlifting and boxing o...

  7. SU-C-BRD-05: Implementation of Incident Learning in the Safety and Quality Management of Radiotherapy: The Primary Experience in a New Established Program with Advanced Techniques

    Energy Technology Data Exchange (ETDEWEB)

    Yang, R; Wang, J [Peking University Third Hospital, Beijing, Beijing (China)

    2014-06-15

    Purpose: To explore the implementation and effectiveness of incident learning for the safety and quality of radiotherapy in a new established radiotherapy program with advanced technology. Methods: Reference to the consensus recommendations by American Association of Physicist in Medicine, an incident learning system was specifically designed for reporting, investigating, and learning of individual radiotherapy incidents in a new established radiotherapy program, with 4D CBCT, Ultrasound guided radiotherapy, VMAT, gated treatment delivered on two new installed linacs. The incidents occurring in external beam radiotherapy from February, 2012 to January, 2014 were reported. Results: A total of 33 reports were analyzed, including 28 near misses and 5 incidents. Among them, 5 originated in imaging for planning, 25 in planning, 1 in plan transfer, 1 in commissioning and 1 in treatment delivery. Among them, three near misses originated in the safety barrier of the radiotherapy process. In terms of error type, 1 incident was classified as wrong patient, 7 near misses/incidents as wrong site, 6 as wrong laterality, 5 as wrong dose, 7 as wrong prescription, and 7 as suboptimal plan quality. 5 incidents were all classified as grade 1/2 of dosimetric severity, 1 as grade 0, and the other 4 as grade 1 of medical severity. For the causes/contributory factors, negligence, policy not followed, inadequate training, failure to develop an effective plan, and communication contributed to 19, 15, 12, 5 and 3 near misses/incidents, respectively. The average incident rate per 100 patients treated was 0.4; this rate fell to 0.28% in the second year from 0.56% in the first year. The rate of near miss fell to 1.24% from 2.22%. Conclusion: Effective incident learning can reduce the occurrence of near miss/incidents, enhance the culture of safety. Incident learning is an effective proactive method for improving the quality and safety of radiotherapy.

  8. Establishment and preliminary application of an ELISA method for determination of pertactin%检测百日咳黏着素的酶联免疫吸附法的建立及初步应用

    Institute of Scientific and Technical Information of China (English)

    王玲; 潘殊男; 张霖阳; 夏菊; 王宇星; 张萍; 肖詹蓉

    2014-01-01

    目的 建立定量检测白喉-破伤风-无细胞百日咳疫苗生产过程中黏着素(pertactin,Prn)的方法.方法 纯化的Prn免疫家兔以制备高效价血清抗Prn抗体.辛酸-硫酸铵沉淀法纯化抗Prn多克隆抗体并进行辣根过氧化物酶标记,建立双抗体夹心ELISA法.结果 建立的方法与丝状血凝素和百日咳毒素无交叉反应,特异性较好.该ELISA法在1.25 ~ 80.00μg/L Prn测量区间有最佳线性,相关系数>0.99.实验内和实验间检测64.0、32.0、16.0 μg/L Prn,变异系数为2.6%~7.7%,回收率为84.9%~ 95.5%,精密度和准确度均符合常规质控要求,因此该法的定量限度为16.0 μg/L.结论 建立的ELISA法可有效检测百日咳疫苗纯化过程中的Prn含量,为组分百日咳疫苗质量控制奠定了重要基础.%Objective To establish an ELISA method for quantitative determination of pertactin (Prn) during production of combined diphtheria,tetanus and acellular pertussis vaccine.Methods Rabbits were immuned with purified Prn to prepare high-titer serum antibodies against Prn.The polyclonal antibodies against Prn were purified by octanoic acid-ammonium sulfate precipitation method and labeled with horseradish peroxidase to establish a double antibody sandwich ELISA method.Results The ELISA method had good specificity for Prn and no cross reaction with filamentous hemagglutinin and pertussis toxin.The best linearity of the ELISA method was formed in the range of 1.25-80.00 μg/L (r > 0.99).The coefficient of variation and recover rates of intra-and inter-assay were 2.6%-7.7% and 84.9%-95.5% respectively when 64.0,32.0 and 16.0 μg/L standard Prn were detected,and the precision and accuracy both met requirements of quality control.The quantitative limit was 16.0 μg/L.Conclusion The established ELISA method can be applied to detecting Prn during purification of pertussis vaccine and lay the foundation for quality control of Prn.

  9. Establishment and preliminary application of an ELISA method for determination of tetanus toxoid%检测破伤风类毒素的酶联免疫吸附法的建立及应用

    Institute of Scientific and Technical Information of China (English)

    王玲; 王珣; 韩俊杰; 张建玲; 杨云凯; 张娜; 佟芳; 潘殊男; 张霖阳

    2016-01-01

    Objective To establish an ELISA method for quantitative determination of tetanus toxoid (TT ) for DTaP .Methods Rabbits were immunized with purified TT to prepare high‐titer serum antibodies against TT .Polyclonal anti‐TT antibodies were purified by octanoic acid‐ammonium sulfate precipitation method and labeled with horseradish peroxidase to establish a double antibody sandwich ELISA method .Results The ELISA method had good specificity for TT and no cross reactivities with filamentous hemagglutinin ,pertussis toxin or diphtheria toxoid .The best linearity of the ELISA method was within the range of 0 .5‐16 .0 Lf /L TT (R 2 > 0 .99) .The coefficient of variation and recover rates of intra‐ and inter‐assay were 4 .7% ‐9 .8% and 92 .7% ‐109 .0% ,respectively ,when 14 .0 ,12 .0 ,6 .0 ,3 .0 and 1 .5 Lf /L TT standards were detected ,and the precision and accuracy both met requirements of quality control . The detection limit of the ELISA method was 1 .5 Lf /L TT . Conclusion The established ELISA method can be applied to detecting TT during purification of tetanus vaccine and lays foundation for quality control of TT .%目的:建立定量检测白喉‐破伤风‐无细胞百日咳疫苗生产过程中破伤风类毒素(tetanus toxoid ,TT )的方法。方法 TT 免疫家兔以制备高效价血清抗 TT 抗体。辛酸‐硫酸铵沉淀法纯化抗TT 多克隆抗体并进行辣根过氧化物酶标记,建立双抗体夹心 ELISA 法。结果建立的 ELISA 法与丝状血凝素、百日咳毒素及白喉类毒素无交叉反应,特异性较好。该 ELISA 法在0.5~16.0 Lf /L TT 检测区间有最佳线性,决定系数>0.99。实验内和实验间检测14.0、12.0、6.0、3.0和1.5 Lf/L TT ,变异系数为4.7%~9.8%,回收率为92.7%~109.0%,精密度和准确度均符合常规质控要求。该法的定量下限为1.5 Lf/L TT 。结论建立的 ELISA 法可有效检测破

  10. 基于目标管理的高校教师科研绩效管理体系构建初探%On the Preliminary Establishment of University Scientific Research Performance Management System Based on Management by Objective

    Institute of Scientific and Technical Information of China (English)

    张日颖; 穆婕

    2013-01-01

    This paper firstly applies Management by Objective to university research performance management process, trying to analyze the content of university research performance management and management system principles; and then it puts forward the proposals of the establishment of university research Performance Management System based on the analysis of university research performance management organization;and finally it analyses the implementation of the management system and its operation mechanism.%本文将目标管理理论应用于高校科研绩效管理过程,分析了高校科研绩效管理的内涵、管理体系构建原则,并在分析了高校科研绩效管理组织机构构成的基础上,提出了高校科研绩效管理体系构建方案,并分析了管理体系的实施与运行机制。

  11. Improving the cardio protective effect of aFGF in ischemic myocardium with ultrasound-mediated cavitation of heparin modified microbubbles: preliminary experiment.

    Science.gov (United States)

    Zhao, Ying-Zheng; Lu, Cui-Tao; Li, Xiao-Kun; Tang, Qin-Qin; Tian, Xin-Qiao; Zhao, Ya-Ping; Zhang, Yan; Tian, Ji-Lai; Yang, Wei; Ge, Shuping; Nair, Chandra K; Shen, Xuedong

    2012-08-01

    Ultrasound (US)-mediated cavitation of microbubbles has evolved into a new tool for organ-specific gene and drug delivery. This paper was to investigate the feasibility of acidic fibroblast growth factor (aFGF) intravenous delivery to the ischemic myocardium of rats by ultrasonic microbubbles modified with heparin. Heparin modified microbubbles (HMB) were prepared by the freeze-dried method. Acute myocardial infarction (AMI) model was established and the cardio protective effect of the aFGF combing with HMB (aFGF-HMB) under US-mediated cavitation technique was investigated. aFGF-HMB combined with US-mediated cavitation technique was examined by ECG. Ejection fraction (EF), fractional shortening (FS) and left ventricular diastolic diameter (LVDd) were measured to monitor the improvement of global myocardial contractile function. Myocardial tissue was stained with hematoxylin and eosine (HE) to evaluate the elaborate general morphology of the ischemic myocardium. From morphologic observation and echocardiography in rat heart, aFGF-HMB had suitable size distribution, physical stability and good acoustic resonance function. From AMI rat experiments, aFGF-HMB under US-mediated cavitation technique exerted aFGF cardio protective effect in ischemic myocardium. From histological evaluation, US-mediated cavitation of aFGF-HMB showed improvement of myocardial ischemia. With the visual imaging and US-triggered drug release advantages, US-mediated cavitation of aFGF-HMB might be developed as a novel technique for targeting delivery of aFGF into ischemic myocardium.

  12. Experiences with Rice Grown on Permanent Raised Beds:Effect of Crop Establishment Techniques on Water Use, Productivity, Profitability and Soil Physical Properties

    Institute of Scientific and Technical Information of China (English)

    R.K.NARESH; S.S.TOMAR; Dipender KUMAR; Samsher; Purushottam; S.P.SINGH; Ashish DWIVEDI; Vineet KUMAR

    2014-01-01

    In recent years, conventional rice production technologies have been leading to deterioration of soil health and declining farm profitability due to high inputs of water and labor. Conservation agriculture (CA) based resource-conserving technologies i.e. zero-tillage (ZT), raised-bed planting and direct-seeded rice (DSR) have shown promise as alternatives to conventional production technologies to overcome these problems. Present study was undertaken during 2009-2012 to establish an understanding of how permanent raised bed cropping system could be practiced to save water at the field application level to improve water productivity and also have the capability to enhance productivity, profitability and soil physical quality. The results showed that among different crop establishment techniques, conventional-tilled puddle transplanted rice (CT-TPR) required 14%-25% more water than other techniques. Compared with the CT-TPR system, zero till direct-seeded rice (ZT-DSR) consumed 6%-10%less water with almost equal system productivity and demonstrated higher water productivity. Wide raised beds saved about 15%-24% water and grain yield decrease of about 8%. Direct-seeded rice after ZT or reduced tillage or on unpuddled soil provided more net income than CT-TPR. The CT-TPR system had higher bulk density and penetration resistance due to compaction caused by the repeated wet tillage in rice. The steady-state infiltration rate and soil aggregation (> 0.25 mm) were higher under permanent beds and ZT and lower in the CT-TPR system. Under CT-TPR, soil aggregation was static across seasons, whereas it improved under no-till and permanent beds. Similarly, mean weight diameter of aggregates was higher under ZT and permanent beds and increased over time. The study reveals that to sustain the rice productivity, CA-based planting techniques can be more viable options. However, the long-term effects of these alternative technologies need to be studied under varying agro-ecologies in

  13. 电工电子实验教学示范中心建设探索%Exploration of Establishing Electrical and Electronic Experiment Center

    Institute of Scientific and Technical Information of China (English)

    郗艳华; 张辉; 王西明

    2013-01-01

    Students' practical ability and innovation ability can be promoted, the integration of resources sharing can be got, and school-running level and teaching quality can be enhanced by the construction of experimental teaching demonstration center. To improve power of professional applied talents training quality, exploration of the construction of electrical and electronic ex-perimental teaching demonstration center of ideas is provided by constructing the hierarchical experimental teaching system, opti-mizing experiment content, riching teaching methods and means, strengthening the construction of teaching staff and the experi-mental teaching platform construction.%实验教学示范中心建设能推动学生实践能力和创新能力培养,促进资源整合共享,提高学校办学水平和教学质量。该文提出了从构建实验教学平台,改革实验教学体系,优化实验教学方法和手段以及加强师资队伍建设等方面探索电工电子实验教学示范中心建设的思路,为提高电类专业应用型人才培养质量进行探讨。

  14. Established and Emerging Decision Constructs – A Taxonomic Perspective

    Directory of Open Access Journals (Sweden)

    Chris Barry

    2016-06-01

    Full Text Available One might assume information systems (IS are developed so systems enhance the user experience and facilitate a satisfying, productive interaction. From prior research, the authors established this assumption was not safe and certain design features amongst some online retailers were atypical of ‘good’ design elsewhere. It was apparent the transactional process was being used to present consumers with optional extras (and other decisions that not only slowed the process down, but also stressed and agitated users. The research identified some new and unusual decision constructs such as the ‘must-opt’. The objective of the research presented herein is two-fold: to make an incremental contribution in first theorising and then identifying and categorising into a taxonomy some new decision constructs alongside established ones encountered throughout on-line Business-to-Consumer (B2C transactional processes followed by a preliminary study confirming their existence and examining their clarity.

  15. Establishment and Preliminary Assessment of Traditional Chinese Medical Clinical Pathway for Cervical Spondylotic Radiculopathy%神经根型颈椎病中医临床路径的建立和初步评价

    Institute of Scientific and Technical Information of China (English)

    陈博来; 林定坤; 孔畅; 张琥; 陈炳坤; 苏国义; 吴江林; 赵兵德

    2011-01-01

    [目的]建立和实施中医治疗神经根型颈椎病的临床路径,并初步评价其可行性.[方法]以2010年1月~2010年6月在我科行中西医保守治疗临床路径的神经根型颈椎病患者28例为临床路径治疗组[包括4种基本疗法(手法、颈牵引、中药汤剂内服、颈部制动)和3种辅助疗法(平衡针、铍针、非甾体消炎止痛药)],以2005年5月~2009年6月在我科行常规中西医保守治疗的神经根型颈椎病患者31例为中西医保守治疗对照组,观察2组患者的平均住院日、平均住院费用和患者满意度.[结果]2组患者经系统治疗后临床症状均明显缓解或消除,其中治疗组的平均住院日和平均住院费用均明显减少,患者的满意度明显提高(与对照组比较,P<0.05或P<0.01).[结论]建立和实施中医治疗神经根型颈椎病的临床路径是切实可行的,可以规范医生临床诊疗行为,缩短住院天数,降低住院费用,提高患者满意度.%Objective To establish a traditional Chinese medical clinical pathway (TCM-CP) for cervical spondyloti radiculopathy (CSR) and to assess its feasibility preliminarily. Methods Twenty-eight CSR patients,which were admitted from January to June of 2010 and subjected to traditional Chinese medical and western medical clinical pathway, were enrolled into the treatment group. They were given 4 kinds of basic treatment including manipulations, cervical traction, neck immobilization and oral use of decoction of herbal medicine, and 3 kinds of adjuvant treatment including balancing needling, stiletto needling, and oral use of non-steroid anti-inflammatory drug and antalgesic. Thirty-one CSR patients, which were admitted from May of 2005 to June of 2010 and subjected to routine traditional Chinese medical and western medical clinical expectant treatment, were enrolled into the control group. The average hospitalization time, average hospitalization fee and patients' satisfaction were investigated

  16. 论经验和科学信念的确立与更新%Discussion on Establishment and Update of Scientific Beliefs and Experience

    Institute of Scientific and Technical Information of China (English)

    吕仕儒; 杜永清

    2014-01-01

    Although natural science is logical system which has been tested by practice. It’s not pure rational activity from its process of foundation and selecting, illogical factor plays an important role. Meanwhile, the history of science development indicates that experience and scientific belief are not all the same, especially when science revolution is coming, abnormal experience and original scientific belief are conflicting which leads scientists to go in a dilemma and that scientists will make different reactions who have different scientific literacy and cultural background. This article made a research about scientific belief ’s mechanism action, performance appearance and correlations on process of scientific theory’s foundation and selecting, and did a discussion about epistemic subject’s action when experience and scientific belief are conflicting from epistemological and methodological point of view.%自然科学理论虽然是经过实践检验的符合逻辑结构的理论体系;但是,从其建立和选择过程看,并不是一个纯粹的理性活动,非逻辑因素在其中同样起着重要作用。同时,科学发展的历史表明,经验与科学信念并非始终一致,尤其在科学革命来临的时候,常常会出现“反常”的经验图景与原有的科学信念相冲突的情况,这时就会使科学家们处于两难境地,不同文化背景和科学素养的科学家会做出不同的反应。文章对经验和科学信念在科学理论建立及选择过程中的作用机理、表现形态以及相互关系进行了研究;并从认识论和方法论的角度,对经验与科学信念冲突时认识主体的反应进行了探讨。

  17. 实时荧光PCR检测基孔肯雅病毒方法的建立及初步应用%The Establishment of Real Time Fluorescent PCR Detecting Method and Preliminary Application on Pathogenesis of Chikungunya Virus

    Institute of Scientific and Technical Information of China (English)

    方巧云; 琚雄飞; 刘特; 严宇斌; 刘燕; 曾健君

    2012-01-01

    Objective To establish real time PCR (RT -PCR) detection method for Chikungunya virus. Methods Primer and FAM probe were chosen for virus gene. The samples were analyzed by TaqMan - FAM PCR and SYBR Green - based RT - PCR techniques on a fluorescence real - time PCR instrument, and the results were compared with those by conventional RT - PCR. Results TaqMan PCR and SYBR RT - PCR positive rates of Chikungunya virus were 17. 5% and 17. 5% ; the conventional RT - PCR were 15%. These results revealed much rapid and increase sensitivity of the real - time PCR method. There were no significant differences between these methods. Conclusion The fluorescence quantitative PCR provides a more specific, more rapid and sensitive method for quantitative detection of Chikungunya virus. It is helpful for the rapid detection of Chikungunya fever.%目的 建立基孔肯雅病毒的荧光定量PCR检测方法.方法 针对基孔肯雅病毒的基因序列,设计、合成引物、探针及反应体系,摸索出最佳反应条件,建立TaqMan荧光探针法和SYBR荧光染料法.利用建立的方法对30例基孔肯雅热病标本和10份基孔肯雅病毒保存液进行扩增、检测和结果分析,并与常规RT - PCR方法的检测结果进行比对.结果 实时荧光定量PCR法比常规RT - PCR法快速、灵敏.40份标本TaqMan荧光探针法、SYBR荧光染料法和常规RT - PCR方法的阳性率分别为:17.5%、17.5%、15%.统计分析表明,3种方法差异不具有统计学意义.结论 实时荧光定量PCR方法快速且具有较好的特异性、敏感性、重复性,适用于基孔肯雅病毒的快速检验.

  18. 血清抗碳酸酐酶Ⅲ抗体ELISA检测方法的建立与初步应用%Establishment and preliminary application of the ELISA method for anti-carbonic anhydrase III antibody detection

    Institute of Scientific and Technical Information of China (English)

    刘辰庚; 王培昌

    2011-01-01

    目的 建立人血清抗碳酸酐酶(CA)Ⅲ抗体的ELISA检测方法,并对系统性红斑狼疮、皮肌炎、糖尿病肾病、高血压肾病患者和健康人群的血清抗CAⅢ抗体水平进行初步调查.方法 使用抗CAⅢ抗体标准品、CAⅢ及相应酶标抗体建立血清抗CAⅢ抗体ELISA检测方法,验证试剂稳定性、标本保存稳定性,并进行精密度、灵敏度、回收率、抗干扰性等方法学评价;各项技术指标均合格后对系统性红斑狼疮、皮肌炎、糖尿病肾病和高血压肾病患者的血清进行抗CAⅢ抗体水平检测.结果 成功建立ELISA检测人血清抗CAⅢ抗体的方法,其批内精密度为6.2%,批间精密度为8.2%,灵敏度为0.025,回收率为106%,且具有较好的抗干扰性、试剂稳定性和标本保存稳定性.系统性红斑狼疮和糖尿病肾病患者的血清抗CAⅢ抗体水平高于健康对照相(P<0.05),阳性率分别为43%和18%.皮肌炎和高血压肾病患者的血清抗CAⅢ抗体水平与健康对照组比较无统计学差异(P>0.05),且未出现阳性结果.结论 使用现有市售试剂进行人血清抗CAⅢ抗体的ELISA检测是可行的,抗CAⅢ抗体可能参与了系统性红斑狼疮和糖尿病肾病的发生发展.%Objective To establish an ELISA method for anti-carbonic anhydrase III (CA III ) antibody detection, and to evaluate the serum level of anti-CA III antibody in normal control group and patients with systemic lupus erythemato-sus, dermatomyositis, 2-type diabetic nephropathy and hypertensive nephropathy respectively. Methods To establish the ELISA method using CA III, anti-CA III antibody and enzyme labeled secondary antibody. To evaluate the stability of the regent and sample, and the sensitivity, stability and anti-interference performance of the ELISA method. To investigate the anti-CA III antibody level in serum of normal control group and patients with systemic lupus erythematosus, dermatomyositis, 2-type

  19. Preliminary Establishment of Transplanted Human Chronic Myeloid Leukemia Model in Nude Mice%移植性慢性髓系白血病裸鼠模型的初步建立

    Institute of Scientific and Technical Information of China (English)

    李先敏; 丁昕; 章龙珍; 岑建农; 陈子兴

    2011-01-01

    慢性髓系白血病(chronic myeloid leukemia,CML)是一种起源于造血干细胞的恶性克隆性疾病,CML干细胞被认为是导致疾病发生、发展并最终急变的根源,目前尚缺乏稳定的动物模型证明CML干细胞的存在.本研究旨在通过建立CML裸鼠模型,探讨人CML细胞在BABL/c裸小鼠体内的生物学行为,并使CML干细胞在裸鼠体内富集成为可能.对4至6周龄的BALB/c裸鼠进行切脾(splenectomy,S),环磷酰胺腹腔注射(cytoxan intraperitoneal injection,c)及全身亚致死剂量照射(sublethal irradiation,I)等预处理(SCI)后,经尾静脉接种(5 -8)×107个人CML慢性期患者单个核细胞.对4至6周龄的BALB/c裸鼠进行全身致死剂量照射(lethal irradiation)后,经尾静脉接种5×106同源裸鼠骨髓细胞和(5 -8)×107个人CML慢性期患者单个核细胞.应用RT-PCR、塑胶包埋病理切片以及流式细胞术等检测裸鼠各脏器及骨髓中人CML细胞浸润情况,并比较两种建模方法的优劣.结果表明,CML细胞能浸润至经SCI预处理的裸鼠骨髓体内,但目前成功率还很低,仅为通过BABL/c裸鼠建立人CML动物模型的一个开端.而经致死剂量预处理裸鼠,CML细胞未能浸润至骨髓.结论:人CML慢性期白血病细胞能在经SCI预处理的裸鼠体内形成白血病,为建立CML动物模型寻找到新的方向.%Chronic myeloid leukemia (CML) is a malignant clonal disease derived from hematopoietic stem cells. CML stem cells were thought to be the root which could lead disease development and ultimately rapid change. However, a stable animal model for studying the characteristics of CML stem cells is currently lacking. This study was aimed to establish a transplanted human CML nude-mice model to further explore the biological behavior of CML stem cells in vivo, and to enrich CML stem cells in nude mice by series transplantation. The 4-6 weeks old BALB /c nude mice pretreated by splenectomy (S), cytoxan intraperitoneal

  20. Out of the Dark: Establishing a Large-Scale Field Experiment to Assess the Effects of Artificial Light at Night on Species and Food Webs

    Directory of Open Access Journals (Sweden)

    Stephanie I. J. Holzhauer

    2015-11-01

    Full Text Available Artificial light at night (ALAN is one of the most obvious hallmarks of human presence in an ecosystem. The rapidly increasing use of artificial light has fundamentally transformed nightscapes throughout most of the globe, although little is known about how ALAN impacts the biodiversity and food webs of illuminated ecosystems. We developed a large-scale experimental infrastructure to study the effects of ALAN on a light-naïve, natural riparian (i.e., terrestrial-aquatic ecosystem. Twelve street lights (20 m apart arranged in three rows parallel to an agricultural drainage ditch were installed on each of two sites located in a grassland ecosystem in northern Germany. A range of biotic, abiotic, and photometric data are collected regularly to study the short- and long-term effects of ALAN on behavior, species interactions, physiology, and species composition of communities. Here we describe the infrastructure setup and data collection methods, and characterize the study area including photometric measurements. None of the measured parameters differed significantly between sites in the period before illumination. Results of one short-term experiment, carried out with one site illuminated and the other acting as a control, demonstrate the attraction of ALAN by the immense and immediate increase of insect catches at the lit street lights. The experimental setup provides a unique platform for carrying out interdisciplinary research on sustainable lighting.

  1. Human plasma concentrations of herbicidal carbamate molinate extrapolated from the pharmacokinetics established in in vivo experiments with chimeric mice with humanized liver and physiologically based pharmacokinetic modeling.

    Science.gov (United States)

    Yamashita, Masanao; Suemizu, Hiroshi; Murayama, Norie; Nishiyama, Sayako; Shimizu, Makiko; Yamazaki, Hiroshi

    2014-10-01

    To predict concentrations in humans of the herbicidal carbamate molinate, used exclusively in rice cultivation, a forward dosimetry approach was carried out using data from lowest-observed-adverse-effect-level doses orally administered to rats, wild type mice, and chimeric mice with humanized liver and from in vitro human and rodent experiments. Human liver microsomes preferentially mediated hydroxylation of molinate, but rat livers additionally produced molinate sulfoxide and an unidentified metabolite. Adjusted animal biomonitoring equivalents for molinate and its primary sulfoxide from animal studies were scaled to human biomonitoring equivalents using known species allometric scaling factors and human metabolic data with a simple physiologically based pharmacokinetic (PBPK) model. The slower disposition of molinate and accumulation of molinate sulfoxide in humans were estimated by modeling after single and multiple doses compared with elimination in rodents. The results from simplified PBPK modeling in combination with chimeric mice with humanized liver suggest that ratios of estimated parameters of molinate sulfoxide exposure in humans to those in rats were three times as many as general safety factor of 10 for species difference in toxicokinetics. Thus, careful regulatory decision is needed when evaluating the human risk resulting from exposure to low doses of molinate and related carbamates based on data obtained from rats.

  2. Preliminary establishment and application of turfgrass disease risk evaluation system%草坪草病害风险性评估体系的初步建立及应用

    Institute of Scientific and Technical Information of China (English)

    王跃栋; 刘自学; 苏爱莲

    2012-01-01

    In order to find an uniform solution for evaluating the risk of turf diseases, pest risk analysis sys- tem to turf disease was introduced and a model for analyzing the risk level of the pest was developed. Based on the rule of standards for pest measurements (ISPM), fuzzy mathematics theory and characteristics of the turf grass ecosystem, we discussed the criterion of evaluation and calculation measures of the model on the method of AHP and Delphi. In this study, an assessment model, including seventeen evaluation indexes, was established. The estimative equation was R==(P1×P2×P3×P4×P5),Using this model, fivekinds of turfgrass diseases were evaluated. The results showed that the high risk level with the value from 0.6 ~o 0.8 involved three kinds of diseases, such as Rhizoctonia solani,Phythium ultimum and Fusarium spp. The middle risk level with the value from 0.4 to 0.6 involved two kinds of diseases, Puccinia spp. and Drechslera spp. In factual tasks, we should set up strategies of the risk management and make con- crete analysis for concrete problems according to different disease risk levels.%为探索建立统一的草坪草病害风险性评价尺度,本研究引入有害生物风险分析(Pest Risk Analysis)理论。基于有害生物风险分析的规定程序,结合草坪绿地生态系统特点及模糊数学理论,利用德尔菲法及层次分析法,探讨了草坪绿地病害风险分析体系的建立、评价指标和评价值的计算方法。初步建立了三层次17个评价指标的综合评价模型R=(P1×P2×P3×P4×P5)~(1/5),并运用此模型评价了草坪草5种主要病害的风险性危害值。结果表明,草坪草褐斑病(Rhizoctonia solani)、腐霉病(Phythium ultimum)和镰刀菌枯萎病(Fusariumspp.)3种病害的风险性危害值在0.6~0.8,风险级别为高风险;草坪草锈病(Pucciniaspp.)和德氏霉叶枯病(Drechsleraspp.)2种病害的风险性危害值在0.4~0.6,

  3. Wide field of view computed tomography and mid carpal instability: The value of the sagittal radius–lunate–capitate axis – Preliminary experience

    Energy Technology Data Exchange (ETDEWEB)

    Repse, Stephen E., E-mail: stephrep@gmail.com [Department of Diagnostic Imaging, Monash Health, VIC (Australia); Koulouris, George, E-mail: GeorgeK@melbourneradiology.com.au [Melbourne Radiology Clinic, Ground Floor, 3-6/100 Victoria Parade, East Melbourne, VIC (Australia); Centre for Orthopaedic Research, School of Surgery, University of Western Australia, Nedlands, WA (Australia); Troupis, John M., E-mail: john.troupis@gmail.com [Department of Diagnostic Imaging & Monash Cardiovascular Research Centre, Monash Health and Department of Biomedical Radiation Sciences, Faculty of Medicine, Nursing & Health Sciences, Monash University, VIC (Australia)

    2015-05-15

    Highlights: • Unique insight into the assessment of mid carpal instability. • 4D CT using sagittal reconstructions along the radius–lunate–capitate axis. • 4D CT observations of vacuum phenomenon, trigger lunate and capitate subluxation. • Earlier recognition of mid carpal instability. - Abstract: Purpose: Dynamic four dimensional (4D) computed tomography (CT) has recently emerged as a practical method for evaluating complex functional abnormality of joints. We retrospectively analysed 4D CT studies undertaken as part of the clinical management of hand and wrist symptoms. We present our initial experience of 4D CT in the assessment of functional abnormalities of the wrist in a group of patients with mid carpal instability (MCI), specifically carpal instability non-dissociative. We aim to highlight unique features in assessment of the radius–lunate–capitate (RLC) axis which allows insight and understanding of abnormalities in function, not just morphology, which may be contributing to symptoms. Materials and methods: Wide field of view multi-detector CT scanner (320 slices, 0.5 mm detector thickness) was used to acquire bilateral continuous motion assessment in hand flexion and extension. A maximum z-axis coverage of 16 cm was available for each acquisition, and a large field of view (FOV) was used. Due to the volume acquisition during motion, reconstructions at multiple time points were undertaken. Dynamic and anatomically targeted multi-planar-reconstructions (MPRs) were then used to establish the kinematic functionality of the joint. Results: Our initial cohort of 20 patients was reviewed. Three findings were identified which were present either in isolation or in combination. These are vacuum phenomenon, triggering of the lunate and capitate subluxation. We provide 4D CT representations of each and highlight features considered of clinical importance and their significance. We also briefly discuss how the current classifications of dynamic wrist

  4. 新型国产颈椎间盘实验山羊模型的建立及初步研究%Establishment of new home-made cervical disc experimental goat model and preliminary study

    Institute of Scientific and Technical Information of China (English)

    王逢贤; 徐林; 俞兴; 曹旭; 杨永栋

    2013-01-01

    Objective To observe the effect of new home-made cervical artificial disc system implantation goats,so as to provide a basis for further improvement and clinical applications.Methods 12 experimental goats were randomly divided into 2 groups:CDR group and control group.Neck 3/4 plate were removed in CDR group,replaced by home-made cervical disc prosthesis.The disc space height (DSH),intervertebral angle (ⅣA) and lordosis angle (LA) at this segment were observed by X ray preoperatively,and postoperatively,and analyzed statistically.Results All experiment goats survived after operation,without incision infection and paralysis,statistical comparison showed no significant difference between the 2 groups ofDSH,ⅣA and LA.Conclusion New home-made artificial cervical disc system is easy to operate,has less blood loss,shorter operative time,less complications and early recovery of movement,and maintaining postoperative disc space height and cervical lordosis.%目的 观察新型国产人工颈椎间盘系统植入山羊体内的效果,为其进一步改进和临床应用提供基础.方法 12只实验山羊随机分为2组,手术组摘除颈3/4间盘,行国产人工颈椎间盘植入术,对照组不手术.分不同时间点行颈椎正侧位X线检查,测量椎间隙高度、椎间角、前凸角,并进行统计学分析.结果 动物实验中所有山羊均成活,无切口感染及瘫痪,统计学比较显示,不同时间点的椎间隙高度、椎间角、前凸角无显著性差异.结论 新型国产人工颈椎间盘系统操作简便,手术中出血量少,手术时间短,术后动物并发症少,恢复活动早,术后较好的保持了椎间隙高度和生理曲度.

  5. 荣昌猪电子耳蜗植入方法建立及听功能初步观察%Establish the standard method of Rongchang pig cochlear implant and preliminary observation of hearing function

    Institute of Scientific and Technical Information of China (English)

    陈伟; 陈磊; 杨仕明; 刘日渊; 张亮; 冀飞; 郭维维; 任丽丽; 李佳楠; 袁硕龙; 张悦

    2016-01-01

    目的:建立在大型哺乳动物-猪体内植入电子耳蜗的方法,观察电子耳蜗植入前后听功能变化。方法荣昌猪6只,雌雄不限,40-45日龄,体重8~12Kg,均选自重庆畜牧科学院养猪研究所。分为听力正常组(Mitf+/+),与突变耳聋组(Mitf-/-),每组3只。在全麻下进行电子耳蜗植入术。于手术前,手术后即刻以及手术后1周记录听性脑干反应(Auditory Brainstem Response,ABR),和电刺激脑干诱发电位(Electrical Auditory Brainstem Response, EABR);头颅X片观察电极植入位置。结果6只动物电子耳蜗植入手术成功,耳蜗电极位置正确,在耳蜗内盘绕1.5~1.75圈。电子耳蜗植入即刻,手术侧(右耳)各频率ABR阈值在120 dB SPL无法引出;手术后7天,手术侧(右耳),低频ABR阈值在100dB SPL左右,高频在120 dB SPL仍无法引出。听力正常荣昌猪组(Mitf+/+),电子耳蜗植入手术即刻及一周后EABR阈值在90 CL左右,明显低于突变耳聋荣昌猪组(Mitf-/-)的190 CL。结论本研究建立的荣昌猪电子耳蜗植入方法确实可行,通过植入电极进行EABR测试方法设计合理。为更加直接地研究电子耳蜗植入设备在体内的工作状态和各项数据,研究电极植入后耳蜗的生理病理改变创造了条件。%Objective Establish the standard method of cochlear implant on large mammals–pigs, and observed the changes of ABR&EABR before and after cochlear implants. Methods Six Rongchang pigs, male and female un-limited, 40-45 days, 8~12 kg, were selected from Key Laboratory of Pig Industry Sciences (Ministry of Agriculture), Chongqing Academy of Animal Science. Divided into the normal hearing group (Mitf+/+), and the mutation deafness group (Mitf-/-), each group of three. Cochlear implantation were operated in general anesthesia. ABR&EABR were recorded prior to surgery, immediately finish surgery and 1 week after. Observed

  6. Preliminary results of ANAIS-25

    CERN Document Server

    Amaré, J; Cuesta, C; García, E; Ginestra, C; Martínez, M; Oliván, M A; Ortigoza, Y; de Solórzano, A Ortiz; Pobes, C; Puimedón, J; Sarsa, M L; Villar, P; Villar, J A

    2013-01-01

    The ANAIS (Annual Modulation with NaI(Tl) Scintillators) experiment aims at the confirmation of the DAMA/LIBRA signal using the same target and technique at the Canfranc Underground Laboratory. 250 kg of ultrapure NaI(Tl) crystals will be used as a target, divided into 20 modules, each coupled to two photomultipliers. Two NaI(Tl) crystals of 12.5 kg each, grown by Alpha Spectra from a powder having a potassium level under the limit of our analytical techniques, form the ANAIS-25 set-up. The background contributions are being carefully studied and preliminary results are presented: their natural potassium content in the bulk has been quantified, as well as the uranium and thorium radioactive chains presence in the bulk through the discrimination of the corresponding alpha events by PSA, and due to the fast commissioning, the contribution from cosmogenic activated isotopes is clearly identified and their decay observed along the first months of data taking. Following the procedures established with ANAIS-0 and ...

  7. Factors for and against establishing and working in private practice correlated with work-related behavior and experience patterns of Ferman physicians in Schleswig-Holstein: A 2-year longitudinal study.

    Science.gov (United States)

    Voltmer, Edgar; Spahn, Claudia; Frank, Erica

    2017-05-08

    To identify factors in favor of or against establishing and working in private practice, to determine the quality of life and work-related behavior and experience patterns of German physicians working in private practice, and to analyze the correlation of those factors. A representative sample of physicians in private practice in Schleswig-Holstein, Germany, was surveyed according to a 2-year longitudinal design (T1 - 2008, N = 549 and T2 - 2010, N = 414). The study included 22 items regarding the attractiveness of establishing and working in private practice, and the questionnaires: the Short Form-12 Health Survey (SF-12), and Work-related Behavior and Experience Pattern (Arbeitsbezogenes Verhaltens- und Erlebensmuster - AVEM). Job satisfaction among those private practitioners decreased over time but their willingness to choose the profession once again remained unchanged. Patient care and the continuity of physician-patient relationship encouraged establishing and working in private practice; state regulation, financial risk, and administrative effort weighed against it. At both T1 and T2, physicians scored significantly lower for mental health than general population. About 20% of physicians showed a healthy behavior and experience pattern but 40% of them showed the pattern of reduced working motivation. About 20% of participants were at elevated risk for overexertion and for burnout. Physical and mental health as well as the total distribution of patterns did not change significantly during the 2-year observation period. Physicians at higher burnout risk rated tasks related to patient care considerably less positively than those with healthy pattern. In order to improve job satisfaction and quality of life, and to make private practice more attractive, those German physicians require a) improved legislation, b) educational programs that promote the attractiveness of private practice, and c) highly accessible counseling services for the prevention and treatment

  8. Factors for and against establishing and working in private practice correlated with work-related behavior and experience patterns of Ferman physicians in Schleswig-Holstein: A 2-year longitudinal study

    Directory of Open Access Journals (Sweden)

    Edgar Voltmer

    2017-06-01

    Full Text Available Objectives: To identify factors in favor of or against establishing and working in private practice, to determine the quality of life and work-related behavior and experience patterns of German physicians working in private practice, and to analyze the correlation of those factors. Material and Methods: A representative sample of physicians in private practice in Schleswig-Holstein, Germany, was surveyed according to a 2-year longitudinal design (T1 – 2008, N = 549 and T2 – 2010, N = 414. The study included 22 items regarding the attractiveness of establishing and working in private practice, and the questionnaires: the Short Form-12 Health Survey (SF-12, and Work-related Behavior and Experience Pattern (Arbeitsbezogenes Verhaltens- und Erlebensmuster – AVEM. Results: Job satisfaction among those private practitioners decreased over time but their willingness to choose the profession once again remained unchanged. Patient care and the continuity of physician-patient relationship encouraged establishing and working in private practice; state regulation, financial risk, and administrative effort weighed against it. At both T1 and T2, physicians scored significantly lower for mental health than general population. About 20% of physicians showed a healthy behavior and experience pattern but 40% of them showed the pattern of reduced working motivation. About 20% of participants were at elevated risk for overexertion and for burnout. Physical and mental health as well as the total distribution of patterns did not change significantly during the 2-year observation period. Physicians at higher burnout risk rated tasks related to patient care considerably less positively than those with healthy pattern. Conclusions: In order to improve job satisfaction and quality of life, and to make private practice more attractive, those German physicians require a improved legislation, b educational programs that promote the attractiveness of private practice

  9. Neurografía por resonancia magnética en 3T: experiencia preliminar 3T MRI neurography: preliminary experience

    Directory of Open Access Journals (Sweden)

    Martín Aguilar

    2012-12-01

    Asymmetry and Least-squares estimation sequence in the evaluation of peripheral nerves, brachial plexus and lumbar plexus, for the diagnosis of compression or entrapment neuropathies, non-entrapment neuropathies, and the underlying conditions. The IDEAL sequence provides 4 types of images from a single acquisition, allowing uniform fat or water suppression and in phase/out of phase images of water, fat or a combination of both. Materials and Methods. This is a retrospective study, from January 2011 to June 2011. Eleven neurographies were performed on 3T MRI (HDX 3T, GE Healthcare, USA, with 8-channel phased array coils on sagittal and coronal planes, with 1.2-0 mm slices with no gap, axial 3D spoiled gradient recalled (SPGR T , with 1-0-mm slice thickness with and without gadolinium injection and variable field of view (FOV according to the nerve or plexus to explore. Results. We found 2 schwannomas (brachial plexus and sciatic nerve, 1 neuritis (compression to median nerve, 2 cases of multiple neurofibromas (lumbosacral plexus, sciatic nerve, brachial plexus, 3 traumatic neuromas (peroneal nerve and 1 pseudomeningocele avulsion (brachial plexus, and 2 with no structural alterations (lumbosacral plexus and peroneal nerve. Conclusion. In this preliminary experience, the use of highresolution sequences in magnetic resonance imaging neurography studies provided excellent signal homogeneity, improving the recognition of the nerve structure and signal, the identification of anatomical variations, and causes of neuropathy, as well as the characterization of denervation changes of the affected muscle groups.

  10. Validation of the TRACE code for the system dynamic simulations of the molten salt reactor experiment and the preliminary study on the dual fluid molten salt reactor

    Energy Technology Data Exchange (ETDEWEB)

    He, Xun

    2016-06-14

    Molten Salt Reactor (MSR), which was confirmed as one of the six Generation IV reactor types by the GIF (Generation IV International Forum in 2008), recently draws a lot of attention all around the world. Due to the application of liquid fuels the MSR can be regarded as the most special one among those six GEN-IV reactor types in a sense. A unique advantage of using liquid nuclear fuel lies in that the core melting accident can be thoroughly eliminated. Besides, a molten salt reactor can have several fuel options, for instance, the fuel can be based on {sup 235}U, {sup 232}Th-{sup 233}U, {sup 238}U-{sup 239}Pu cycle or even the spent nuclear fuel (SNF), so the reactor can be operated as a breeder or as an actinides burner both with fast, thermal or epi-thermal neutron spectrum and hence, it has excellent features of the fuel sustainability and for the non-proliferation. Furthermore, the lower operating pressure not only means a lower risk of the explosion as well as the radioactive leakage but also implies that the reactor vessel and its components can be lightweight, thus lowering the cost of equipments. So far there is no commercial MSR being operated. However, the MSR concept and its technical validation dates back to the 1960s to 1970s, when the scientists and engineers from ORNL (Oak Ridge National Laboratory) in the United States managed to build and run the world's first civilian molten salt reactor called MSRE (Molten Salt Reactor Experiment). The MSRE was an experimental liquid-fueled reactor with 10 MW thermal output using {sup 4}LiF-BeF{sub 2}-ZrF{sub 4}-UF{sub 4} as the fuel also as the coolant itself. The MSRE is usually taken as a very important reference case for many current researches to validate their codes and simulations. Without exception it works also as a benchmark for this thesis. The current thesis actually consists of two main parts. The first part is about the validation of the current code for the old MSRE concept, while the second

  11. 植物生理学实验中溶液培养研究性实验的建立研究%The establishment of hydroponics research experiment in plant physiology experiment

    Institute of Scientific and Technical Information of China (English)

    刘阳; 董树刚

    2015-01-01

    Hydroponics experiment is an important content of the teaching in plant physiology .However , the content of this part is mo-notonous in the old syllabus .The author tries to combine the basic experiment with hydroponics experiment in his teaching .Using hy-droponics as a technology and guiding students to carry out research experiment , the author′s teaching innovation has achieved good re-sults, training students′practical ability, observation ability, comprehensive ability and innovation ability .%溶液培养实验是植物生理学实验教学中的重要内容,而旧的教学大纲中该部分内容设置单一,不利于学生的理解掌握。笔者在教学实践中,将基础性实验与溶液培养实验有机结合,以溶液培养为技术手段,引导学生开展研究性实验,锻炼学生的动手能力,培养学生的观察能力、综合能力和创新能力,取得了较好的效果。

  12. Realization and preliminary measurements on a 94 GHz SIS mixer

    CERN Document Server

    Oberto, L; Fretto, M; Tartari, A; Brunetti, L; Lacquaniti, V

    2010-01-01

    In this paper we present the realization and a preliminary characterization of a SIS based receiver. It has been developed for the MASTER experiment that consists in a three-band SIS receiver (94, 225 and 345 GHz) for astrophysical observations through the atmospheric windows available at high altitude dry sites. The measurements performed establish an upper limit to the overall receiver noise temperature. A comparison has been tried with the MASTER requirements and with state of the art results. A noise figure of 110 K has been obtained at 94 GHz, about 22 times the quantum limit.

  13. Diagnosis and immunophenotype of 188 pediatric lymphoblastic lymphomas treated within a randomized prospective trial: experiences and preliminary recommendations from the European childhood lymphoma pathology panel.

    NARCIS (Netherlands)

    Oschlies, I.; Burkhardt, B.; Chassagne-Clement, C.; d'Amore, E.S.; Hansson, U.; Hebeda, K.M.; McCarthy, K.; Kodet, R.; Maldyk, J.; Mullauer, L.; Porwit, A.; Schmatz, A.I.; Tinguely, M.; Abramov, D.; Wotherspoon, A.; Zimmermann, M.; Reiter, A.; Klapper, W.

    2011-01-01

    The majority of lymphoblastic (precursor cell) neoplasms presents as leukemias. Consequently, the guidelines for lineage determination and subtyping of precursor cell neoplasms were primarily established for flow cytometry methods. Large-scale studies of nonleukemic lymphoblastic lymphomas are lacki

  14. Preliminary Collaborative Steps in Establishing CEFR Sign Language Levels

    NARCIS (Netherlands)

    Sadlier, L.; van den Bogaerde, B.; Oyserman, P.; Tsagari, D.; Csepes, I.

    2012-01-01

    This chapter explores the role of the Common European Framework of Reference for Languages (CEFR) in the context of teaching, learning, and more specifically, assessing signed languages. An exploration of various approaches used in selected universities across Europe provides perspectives on how the

  15. Preliminary Results From a Newly Established Behavioral Health Home

    Directory of Open Access Journals (Sweden)

    Alexandros Maragakis

    2015-05-01

    Full Text Available Objective: Individuals with serious mental illness (SMI have higher rates of preventable diseases such as diabetes in comparison to the general population. While multifaceted, these high rates of preventable diseases in the population with SMI may be partially attributed to limited access to primary care. A new program, the Behavioral Health Home (BHH, which allows for the delivery of somatic care coordination and population-based care, may provide this population with the much needed somatic coordination and education it requires. Methods: The impact of the population-based health management program of the BHH identification and severity rating of glucose metabolism disorders was assessed during the initial 10 months of the BHH. Results: Multiple patients were identified who either were not having hemoglobin A1c (HbA1c levels drawn per recommended guidelines for individuals prescribed antipsychotic medications or were within diabetic range but did not have a diagnosis of diabetes. Mixed results occurred in regard to patients’ HbA1c levels while engaging in the BHH. Conclusion: This case study provides some initial evidence for the utility of the BHH in regard to identifying patients who need preventive care.

  16. Re-establishing dignity

    DEFF Research Database (Denmark)

    Høy, Bente; Hall, E.O.C

    2012-01-01

    In western countries, the older population is increasing and with age follows a risk of un-health. Every fifth hospital patient is above 65 years of age. As a consequence, nursing care to older patients is a significant but tacit nursing issue. The aim of this study was to explore Danish clinical...... nurses’ experiences of caring for older hospital patients. The study was based on Benner and Wrubel’s phenomenological notion that caring as a special kind of involvement, a grasp of a situation in terms of its meaning, is primary in nursing. A qualitative secondary analysis of data from an interview...... study with 29 nurses and nurse assistants was performed following Van Manen’s hermeneutic phenomenology. Findings show that caring mainly concerns ‘re-establishing dignity’ especially through ‘seeing the patient as a unique person’, ‘assisting in getting rid of the bed’ and ‘supporting patient...

  17. Preliminary design for a maglev development facility

    Energy Technology Data Exchange (ETDEWEB)

    Coffey, H.T.; He, J.L.; Chang, S.L.; Bouillard, J.X.; Chen, S.S.; Cai, Y.; Hoppie, L.O.; Lottes, S.A.; Rote, D.M. [Argonne National Lab., IL (United States); Zhang, Z.Y. [Polytechnic Univ., Brooklyn, NY (United States); Myers, G.; Cvercko, A. [Sterling Engineering, Westchester, IL (United States); Williams, J.R. [Alfred Benesch and Co., Chicago, IL (United States)

    1992-04-01

    A preliminary design was made of a national user facility for evaluating magnetic-levitation (maglev) technologies in sizes intermediate between laboratory experiments and full-scale systems. A technical advisory committee was established and a conference was held to obtain advice on the potential requirements of operational systems and how the facility might best be configured to test these requirements. The effort included studies of multiple concepts for levitating, guiding, and propelling maglev vehicles, as well as the controls, communications, and data-acquisition and -reduction equipment that would be required in operating the facility. Preliminary designs for versatile, dual 2-MVA power supplies capable of powering attractive or repulsive systems were developed. Facility site requirements were identified. Test vehicles would be about 7.4 m (25 ft) long, would weigh form 3 to 7 metric tons, and would operate at speeds up to 67 m/s (150 mph) on a 3.3-km (2.05-mi) elevated guideway. The facility would utilize modular vehicles and guideways, permitting the substitution of levitation, propulsion, and guideway components of different designs and materials for evaluation. The vehicle would provide a test cell in which individual suspension or propulsion components or subsystems could be tested under realistic conditions. The system would allow economical evaluation of integrated systems under varying weather conditions and in realistic geometries.

  18. Preliminary design for a maglev development facility

    Energy Technology Data Exchange (ETDEWEB)

    Coffey, H.T.; He, J.L.; Chang, S.L.; Bouillard, J.X.; Chen, S.S.; Cai, Y.; Hoppie, L.O.; Lottes, S.A.; Rote, D.M. (Argonne National Lab., IL (United States)); Zhang, Z.Y. (Polytechnic Univ., Brooklyn, NY (United States)); Myers, G.; Cvercko, A. (Sterling Engineering, Westchester, IL (United States)); Williams, J.R. (Alfred Benesch and Co., Chicago, IL (United States))

    1992-04-01

    A preliminary design was made of a national user facility for evaluating magnetic-levitation (maglev) technologies in sizes intermediate between laboratory experiments and full-scale systems. A technical advisory committee was established and a conference was held to obtain advice on the potential requirements of operational systems and how the facility might best be configured to test these requirements. The effort included studies of multiple concepts for levitating, guiding, and propelling maglev vehicles, as well as the controls, communications, and data-acquisition and -reduction equipment that would be required in operating the facility. Preliminary designs for versatile, dual 2-MVA power supplies capable of powering attractive or repulsive systems were developed. Facility site requirements were identified. Test vehicles would be about 7.4 m (25 ft) long, would weigh form 3 to 7 metric tons, and would operate at speeds up to 67 m/s (150 mph) on a 3.3-km (2.05-mi) elevated guideway. The facility would utilize modular vehicles and guideways, permitting the substitution of levitation, propulsion, and guideway components of different designs and materials for evaluation. The vehicle would provide a test cell in which individual suspension or propulsion components or subsystems could be tested under realistic conditions. The system would allow economical evaluation of integrated systems under varying weather conditions and in realistic geometries.

  19. Preliminary design for a MAGLEV development facility

    Science.gov (United States)

    Coffey, H. T.; He, J. L.; Chang, S. L.; Bouillard, J. X.; Chen, S. S.; Cai, Y.; Hoppie, L. O.; Lottes, S. A.; Rote, D. M.; Zhang, Z. Y.

    1992-04-01

    A preliminary design was made of a national user facility for evaluating magnetic-levitation (maglev) technologies in sizes intermediate between laboratory experiments and full-scale systems. A technical advisory committee was established and a conference was held to obtain advice on the potential requirements of operational systems and how the facility might best be configured to test these requirements. The effort included studies of multiple concepts for levitating, guiding, and propelling maglev vehicles, as well as the controls, communications, and data-acquisition and -reduction equipment that would be required in operating the facility. Preliminary designs for versatile, dual 2-MVA power supplies capable of powering attractive or repulsive systems were developed. Facility site requirements were identified. Test vehicles would be about 7.4 m (25 ft) long, would weigh from 3 to 7 metric tons, and would operate at speeds up to 67 m/s (150 mph) on a 3.3-km (2.05-mi) elevated guideway. The facility would utilize modular vehicles and guideways, permitting the substitution of levitation, propulsion, and guideway components of different designs and materials for evaluation. The vehicle would provide a test cell in which individual suspension or propulsion components or subsystems could be tested under realistic conditions. The system would allow economical evaluation of integrated systems under varying weather conditions and in realistic geometries.

  20. 15 CFR 270.101 - Preliminary reconnaissance.

    Science.gov (United States)

    2010-01-01

    ... establishment of a Team, the leader of the initial assessment will report his/her findings to the Director in a... the extent the Director deems it appropriate, the Director may conduct a preliminary reconnaissance at the site of a building failure. The Director may establish and deploy a Team to conduct the...

  1. An Ensemble Ocean Wave Forecast System and Preliminary Experiment%一个集合海浪预报系统及其初步试验

    Institute of Scientific and Technical Information of China (English)

    孙明华

    2011-01-01

    The basic methods of ensemble wave prediction at home and abroad and an ensemble wave numerical forecast system are introduced. The system is established by running the operational wave model WAV-EWATCH H using wind data from the 15 members' ensemble weather forecast system, which is based on the T213L31 model and operational running in China National Meteorological Center. The ensemble model calculates 15 members wave field, including one control forecast and 14 perturbation members forecast. The model computes the waves over all the oceans up to 10 days at 12; 00 with 1° by 1° resolution. Based on hot initialization, the model uses the 12 h wave hindcast as its initial field. Through the information extraction and processing from the 15 member's wave fields, the system produces the ensemble wave products such as ensemble mean and spread, spaghetti charts and probability charts. Forecast experiment for the period from 1 Sep to 31 Oct in 2007 is done using the system and buoys data in the Pacific and Atlantic at the same period. The main verifying indexes are bias and root mean square error. For the mean monthly bias of 10 m wind speed and significant wave height, the performance of the ensemble mean is better than the control forecast, however both of them have a relatively low system deviation and one cause is that the spin up time of the system may not be long enough. For the monthly root mean square error, the ensemble mean of 10 m wind speed is lower than the control forecast by 3-12 percentage for the different forecast periods, meanwhile the ensemble mean of significant wave height is lower than the control forecast by 3- 17 percentage with consistent variation trend. Comparing 15 ensemble members' forecast to the Buoy_ 46006 data, it shows that the ensemble members can follow the changes of the observation well and cover the variation range of the observation other than the deterministic forecast. In summary, the verification results show that the

  2. 机器人外科手术系统体外循环心脏手术的初步经验%Total endoscopic robot-assisted on-pump cardiac surgery: preliminary experience with robot-assisted surgery

    Institute of Scientific and Technical Information of China (English)

    魏来; 黄麒; 王春生; 沈金强; 夏利民; 罗红; 廖庆武; 胡克俭; 王萍; 徐竹静

    2011-01-01

    Objective To introduce our preliminary experience in total endoscopic robot-assisted onpump cardiac surgery with da Vinci system. Methods Five patients with mitral insufficiency (MI) and five patients with atrial septai defect (ASD) underwent on-pump cardiac surgical procedures using da Vinci S system from Aug. 2010 to Dec. 2010. After double-lumen endotracheal intubation and intravenous inhalation anesthesia,the peripheral extracorporeal circulation was established with femoral arterial cannula, femoral venous cannula and right internal jugular venous cannula. Through a 3 cm-length working-port and other three 0.8 cm-length mini-ports,the total endoscopic robotic-assisted operations (including mitral valve repair and ASD repair) were performed.Results All procedures were successfully performed without incision expansion or converting to sternotomy.Transesophageal echocardiography (TEE) showed no moderate or severe .m. itral valve regurgitation or atrial septal shunt. There were no in-hospital death or post-operative complications. The patients recovered quickly with less bleeding and shorter hospital stay. All patients were followed-up for 1 - 3 months and had satisfactory TEE results.Conclusion The da Vinci robotic surgery system is safe and reliable for cardiac surgery, with satisfactory outcome, mini-invasiveness, rapid recovery and bright future. (Shanghai Med J, 2011, 34: 38-42)%目的 介绍复旦大学附属中山医院应用达芬奇S机器人外科手术系统辅助开展全内镜体外循环心脏手术的初步经验.方法 2010年8-12月在达芬奇S机器人外科手术系统辅助下完成全内镜二尖瓣成形术5例,房间隔缺损修补术5例.全组患者均采用双腔气管插管、静脉吸入复合麻醉,经股动脉、股静脉及右颈内静脉插管建立外周体外循环.于右胸第4肋间隙作3 cm工作孔,右胸第3、4、6肋间隙分别作0.8 cm器械孔,由术者操控机械臂完成全内镜下心内直视手术.结果 所有

  3. SSC 40 mm short model construction experience

    Energy Technology Data Exchange (ETDEWEB)

    Bossert, R.C.; Brandt, J.S.; Carson, J.A.; Dickey, C.E.; Gonczy, I.; Koska, W.A.; Strait, J.B.

    1990-04-01

    Several short model SSC magnets have been built and tested at Fermilab. They establish a preliminary step toward the construction of SSC long models. Many aspects of magnet design and construction are involved. Experience includes coil winding, curing and measuring, coil end part design and fabrication, ground insulation, instrumentation, collaring and yoke assembly. Fabrication techniques are explained. Design of tooling and magnet components not previously incorporated into SSC magnets are described. 14 refs., 18 figs., 2 tabs.

  4. Point-of-Care Testing in Bathhouses: A Narrative Inquiry into the Experience of Receiving a Positive Preliminary HIV Test Result.

    Science.gov (United States)

    Genoway, Shyla; Caine, Vera; Singh, Ameeta E; Estefan, Andrew

    2016-01-01

    With a call to increase the accessibility of HIV testing, point-of-care testing for HIV is being readily adopted, but little attention has been paid to the experiences of people being tested at HIV point-of-care sites. Some testing environments, such as bathhouses, promote testing for HIV in higher-risk groups. In this narrative inquiry study we explored the experiences of people testing positive for HIV through point-of-care while at a bathhouse. Three narrative threads for reconsidering the practice were identified: (a) seeing complexities, understanding testing decisions in relation to time, place, and social context; (b) recognizing the impact and significance of secret and silent stories; and (c) tentative and tension-filled connections to care. It is important to understand testing experiences across time, place, and in diverse social contexts. These experiences are embedded within the larger life histories of people and raise questions about adequate support, follow-up, and counseling.

  5. Ruthenium-106 brachytherapy for uveal melanomas. Preliminary results: a single institutional experience; Braquiterapia com rutenio-106 em melanomas uveais. Resultados preliminares: experiencia uni-instuticional

    Energy Technology Data Exchange (ETDEWEB)

    Dias, Rodrigo Souza; Giordani, Adelmo Jose; Segreto, Helena Regina Comodo; Segreto, Roberto Araujo [Universidade Federal de Sao Paulo/Escola Paulista de Medicina (Unifesp/EPM), Sao Paulo, SP (Brazil). Departamento de Medicina. Setor de Radioterapia ; Erwenne, Clelia Maria; Teixeira, Luiz Fernando [Universidade Federal de Sao Paulo/Escola Paulista de Medicina (UNIFESP/EPM), Sao Paulo, SP (Brazil). Dept. de Oftalmologia]. E-mail: segreto. dmed@epm.br

    2007-03-15

    Objective: To analyze the early response of uveal melanomas in patients treated with ruthenium-106 brachytherapy. Materials And Methods: In the period between April 2002 and July 2003, 20 patients diagnosed with uveal melanoma were submitted to ruthenium-106 brachytherapy. The calculated dose delivered at the apex of the tumor ranged between 55 Gy and 100 Gy. Patients with lesions greater than 5 mm were submitted to transpupillary thermotherapy concomitantly with ophthalmic plaque insertion. Results: As regards the lesions site, 75% of the lesions were located in the choroid, 15% in the iris, and the remainder 10% in the ciliary body. In a median 19-month-follow-up, the progression-free survival for brachytherapy was 69%, and 87% for associated brachytherapy and transpupillary thermotherapy. A significant tumor height reduction was observed after treatment. No patient was submitted to enucleation. Conclusion: Our preliminary results show that ruthenium-106 brachytherapy is an appropriate method for conservative treatment of patients with uveal melanomas in terms of local management, ocular and visual acuity preservation with an acceptable complications incidence rate. (author)

  6. RUSSIAN EXPERIENCE WITH USING MONOCLONAL ANTIBODIES TO B-LYMPHOCYTES (RITUXIMAB IN SYSTEMIC VASCULITIDES ASSOCIATED WITH NEUTROPHIL CYTOPLASMIC ANTIBODIES (PRELIMINARY RESULTS OF THE RUSSIAN REGISTER NORMA

    Directory of Open Access Journals (Sweden)

    T. V. Beketova

    2014-01-01

    Full Text Available In 2013, Russia registered officially the indications for the use of monoclonal antibodies to B-lymphocytes (rituximab, RTM in systemic vasculitides associated with antineutrophil cytoplasmic antibodies (ANCA-SV. This communication presents the preliminary results of the Russian register of the RTM application in autoimmune diseases (NORMA that has included 50 patients with ANCA-SV treated in 14 cities of the Russian Federation. Twenty-five of 50 (50% patients received repeated courses of RTM. RTM has demonstrated a high efficacy and a good profile of treatment safety in patients with ANCA-SV in real-life national clinical practice. Among 25 patients who had been followed up for over 12 months, the remission was achieved in 92% of cases, a decrease in the ANCA-SV activity was observed in 8%. The efficacy of RTM increased when performing repeated courses, while it has been noted that the positive results can be obtained by prescribing a repeated course of RTM at a reduced dose (500–1000 mg. Prescription of the repeated courses was primarily required in patients with granulomatosis and polyangiitis affecting the lungs. Care should be taken when combining RTM treatment with cytostatics (primarily with cyclophosphamide because of the risk of secondary immunodeficiency and infectious adverse events (AE, which have been the most frequent serious AE (12% in patients with ANCA-SV.

  7. The innovative viscoelastic CP ESP cervical disk prosthesis with six degrees of freedom: biomechanical concepts, development program and preliminary clinical experience.

    Science.gov (United States)

    Lazennec, Jean-Yves; Aaron, Alain; Ricart, Olivier; Rakover, Jean Patrick

    2016-01-01

    The viscoelastic cervical disk prosthesis ESP is an innovative one-piece deformable but cohesive interbody spacer. It is an evolution of the LP ESP lumbar disk implanted since 2006. CP ESP provides six full degrees of freedom about the three axes including shock absorbtion. The prosthesis geometry allows limited rotation and translation with resistance to motion (elastic return property) aimed at avoiding overload of the posterior facets. The rotation center can vary freely during motion. The concept of the ESP prosthesis is fundamentally different from that of the devices currently used in the cervical spine. The originality of the concept of the ESP® prosthesis led to innovative and intense testing to validate the adhesion of the viscoelastic component of the disk on the titanium endplates and to assess the mechanical properties of the PCU cushion. The preliminary clinical and radiological results with 2-year follow-up are encouraging for pain, function and kinematic behavior (range of motion and evolution of the mean centers of rotation). In this series, we did not observe device-related specific complications, misalignment, instability or ossifications. Additional studies and longer patient follow-up are needed to assess long-term reliability of this innovative implant.

  8. Differences in the relationship between traumatic experiences, self-esteem, negative cognition, and Internet addiction symptoms among North Korean adolescent defectors and South Korean adolescents: A preliminary study.

    Science.gov (United States)

    Park, Subin; Lee, Yeeun; Jun, Jin Yong

    2017-07-31

    North Korean adolescent defectors experience adaptation difficulties along with a wide range of psychosocial problems, but no study has yet examined their Internet addiction symptoms. We compared early traumatic experiences, self-esteem, negative cognition, and Internet addiction symptoms, as well as the relationships between these variables, between North Korean adolescent defectors and South Korean adolescents. Fifty-six North Korean adolescent defectors and 112 age- and sex- matched South Korean adolescents participated. The analyses examined the relationship between traumatic experiences and Internet addiction symptoms, with negative automatic thoughts or low self-esteem as mediators of these relations. North Korean adolescent defectors tended to have higher levels of negative automatic thoughts and more severe Internet addiction symptoms, as well as better self-esteem, than did South Korean adolescents. Furthermore, only among North Korean adolescent defectors, traumatic experiences were positively associated with Internet addition symptoms via increasing negative automatic thoughts. North Korean adolescent defectors are more susceptible to Internet addiction, negative cognitions, and early traumatic experiences compared to South Korean adolescents. However, the cross-sectional design of this study precludes consideration of the causality of these relationships. Interventions aiming to correct negative cognitions and increase self-esteem may be helpful for North Korean adolescent defectors with problematic Internet use. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. 浅谈色度学实验教学内容的规范化%Preliminary Study on the Normalization for Experiment Teaching Contents of Colorimetry Courses

    Institute of Scientific and Technical Information of China (English)

    范秋梅; 邓瑞平; 丁仁强

    2015-01-01

    In consideration of present situation of colorimetry teaching in China universities,e.g.the unevenness of experiment teaching levels, lack of teaching material on experiments etc,it is suggested that on the basis of the teaching material of colorimetry courses,to formulate detailed implementation programs of colorimetry experiments,to prepare experiment instruction material,to normalize the experiment contents of colorimetry,and thus to improve the teaching quality of the course of colorimetry.%针对目前我国高校色度学教学的实际情况,实验教学水平的参差不齐,实验教材的缺乏;建议以色度学教材为依据,研究制订色度学实验的具体实施方案,编写实验指导教材,规范色度学的实验内容;提高色度学的教学质量。

  10. The Disposition of Silver Released from Soviet Oblako Rockets in Precipitation during the Hall Suppression Experiment Grossversuch IV. Part I: Measurements of Background and a Preliminary Seeding Test.

    Science.gov (United States)

    Lacaux, J.-P.; Warburton, J. A.

    1980-07-01

    In association with Grossversuch IV, a program designed to test the Soviet hail suppression method by seeding clouds with AgI from Oblako rockets, a complementary program was conducted by l'Observatoire du Puy-de-Dôme and the Desert Research Institute to study the diffusion of the seeding material (AgI) in the clouds, based on the analysis of silver in precipitation. This program covered the summers of 1977 and 1978, and this paper describes the results of measurements of natural background silver concentrations in unseeded precipitation. It also describes a new automatic precipitation collector, five of which were first tested in the field in 1977. A more extensive network of 15 collectors was deployed during two months of the 1978 summer.Based on the analysis of 118 unseeded precipitation samples collected in 1977, the natural background concentration of silver was estimated as 0.9 × 1011 g mL1( = 0.6 × 1011 g mL1). Although the standard deviations overlap, the 1978 season results appear to indicate a lower background of 0.5 × 1011 g mL1 ( = 0.3 × 1011 g mL1), based on the analysis of 414 rain samples. The average value for the two seasons was 0.6 × 1011 g mL1 with a standard deviation of 0.5 × 1011 g mL1. These background concentrations were found to be independent of both the length of sampling period and the precipitation intensity, averaged over the sampling periods of the collectors.The background is sufficiently low to permit the detection of the presence of silver iodide emitted from the Soviet rockets in the precipitation. The preliminary results from one case study are presented to support this conclusion.

  11. RFID Key Establishment Against Active Adversaries

    CERN Document Server

    Bringer, Julien; Cohen, Gérard; Kindarji, Bruno

    2010-01-01

    We present a method to strengthen a very low cost solution for key agreement with a RFID device. Starting from a work which exploits the inherent noise on the communication link to establish a key by public discussion, we show how to protect this agreement against active adversaries. For that purpose, we unravel integrity $(I)$-codes suggested by Cagalj et al. No preliminary key distribution is required.

  12. 实验昆虫实验动物化的初步研究%Preliminary Research on Experimental Animalization of Experiment Insect

    Institute of Scientific and Technical Information of China (English)

    安学芳; 夏克祥; 朱幼玲

    2003-01-01

    With the development of science and technology, life-science is involving in many fields. The requirements for the methods of experiment and experiment object are more abroad, more strict and more diversified. As laboratory animals of experimental material in the life-science, great changes have taken place since then. As for the exploitation of new kind of laboratory animals, it is not only limited in experimental Animalization of ordinary mammals but also expands steadily from Experimental Animalization of birds, reptiles, fish and invertebrates. Now insects of invertebrate have been used in life science research and are enriched gradually in application fields.

  13. A non-diatom plankton bloom controlled by copepod grazing and amphipod predation: Preliminary results from the LOHAFEX iron-fertilisation experiment

    Digital Repository Service at National Institute of Oceanography (India)

    Mazzocchi, M.G.; Gonzalez, H.E.; Vandromme, P.; Borrione, I.; deAlcala, M.R.; Gauns, M.; Assmy, P.; Fuchs, B.; Klaas, C.; Martin, P.; Montresor, M.; Ramaiah, N.; Naqvi, S.W.A.; Smetacek, V.

    The most memorable LOHAFEX cruise came to an end on 17 March 2009 when RV Polarstern docked in the harbour of Punta Arenas (southern Chile) after successfully carrying out the longest iron fertilisation experiment so far (39 days). The two and a...

  14. Bypass during Liver Transplantation: Anachronism or Revival? Liver Transplantation Using a Combined Venovenous/Portal Venous Bypass—Experiences with 163 Liver Transplants in a Newly Established Liver Transplantation Program

    Directory of Open Access Journals (Sweden)

    Anne Mossdorf

    2015-01-01

    Full Text Available Introduction. The venovenous/portal venous (VVP bypass technique has generally become obsolete in liver transplantation (LT today. We evaluated our experience with 163 consecutive LTs that used a VVP bypass. Patients and Methods. The liver transplant program was started in our center in 2010. LTs were performed using an extracorporal bypass device. Results. Mean operative time was 269 minutes and warm ischemic time 43 minutes. The median number of transfusion of packed cells and plasma was 7 and 14. There was no intraoperative death, and the 30-day mortality was 3%. Severe bypass-induced complications did not occur. Discussion. The introduction of a new LT program requires maximum safety measures for all of the parties involved. Both surgical and anaesthesiological management (reperfusion can be controlled very reliably using a VVP bypass device. Particularly when using marginal grafts, this approach helps to minimise both surgical and anaesthesiological complications in terms of less volume overload, less use of vasopressive drugs, less myocardial injury, and better peripheral blood circulation. Conclusion. Based on our experiences while establishing a new liver transplantation program, we advocate the reappraisal of the extracorporeal VVP bypass.

  15. Bypass during Liver Transplantation: Anachronism or Revival? Liver Transplantation Using a Combined Venovenous/Portal Venous Bypass-Experiences with 163 Liver Transplants in a Newly Established Liver Transplantation Program.

    Science.gov (United States)

    Mossdorf, Anne; Ulmer, Florian; Junge, Karsten; Heidenhain, Christoph; Hein, Marc; Temizel, Ilknur; Neumann, Ulf Peter; Schöning, Wenzel; Schmeding, Maximilian

    2015-01-01

    Introduction. The venovenous/portal venous (VVP) bypass technique has generally become obsolete in liver transplantation (LT) today. We evaluated our experience with 163 consecutive LTs that used a VVP bypass. Patients and Methods. The liver transplant program was started in our center in 2010. LTs were performed using an extracorporal bypass device. Results. Mean operative time was 269 minutes and warm ischemic time 43 minutes. The median number of transfusion of packed cells and plasma was 7 and 14. There was no intraoperative death, and the 30-day mortality was 3%. Severe bypass-induced complications did not occur. Discussion. The introduction of a new LT program requires maximum safety measures for all of the parties involved. Both surgical and anaesthesiological management (reperfusion) can be controlled very reliably using a VVP bypass device. Particularly when using marginal grafts, this approach helps to minimise both surgical and anaesthesiological complications in terms of less volume overload, less use of vasopressive drugs, less myocardial injury, and better peripheral blood circulation. Conclusion. Based on our experiences while establishing a new liver transplantation program, we advocate the reappraisal of the extracorporeal VVP bypass.

  16. Preliminary Monthly Climatological Summaries

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Preliminary Local Climatological Data, recorded since 1970 on Weather Burean Form 1030 and then National Weather Service Form F-6. The preliminary climate data pages...

  17. Structure of Flame Balls at Low Lewis-Number (SOFBALL): Preliminary Results From the STS-83 and STS-94 Space Flight Experiments

    Science.gov (United States)

    Ronney, Paul D.; Wu, Ming-Shin; Pearlman, Howard G.; Weiland, Karen J.

    1998-01-01

    Results from the Structure Of Flame Balls At Low Lewis-number (SOFBALL) space flight experiment conducted on the MSL-1 Space Shuttle missions are reported. Several new insights were obtained, including: much lower buoyancy-induced drift speed than anticipated pre-flight; repulsion of adjacent flame balls due to their mutual interaction; remarkable sensitivity of flame balls to small accelerations resulting from Orbiter attitude control maneuvers; and very similar net heat release for all flame balls in all mixtures tested. Comparison of experimental results to computational predictions reveals limitations in current models of H2-02 chemistry for very lean mixtures. It is discussed how the results of these space experiments may provide an improved understanding of the interactions of the two most important phenomena in combusting materials, namely chemical reaction and transport processes, in the unequivocally simplest possible configuration.

  18. Experiment to determine electrical conductivity and equation of state data from Ohmically exploded tamped planar foils - preliminary diagnostic results and modeling

    Science.gov (United States)

    Ruden, E. L.; Amdahl, D. J.; Brown, D. J.; Grabowski, T. C.; Gregg, C. W.; Kostora, M. R.; Martinez, B. M.; Parker, J. V.; Camacho, J. F.; Coffey, S. K.; Poulsen, P.

    2009-11-01

    Diagnostic results from initial nondestructive (thick foil, low current) tests are presented for an experiment to simultaneously determine the electrical conductivity, pressure, density, specific energy, and temperature time histories of a planar metal foil tamped by a well characterized transparent material and exploded by a 36 μF, 50 kV rated capacitor bank discharge. Voltage differentials measure the foil's surface electric field, a B-dot probe measures surface current density, and a laser velocity interferometer (VISAR) measures dynamic foil thickness. From such and future filtered photodiode measurements, the desired properties will be inferred up to a few eV and within an order of magnitude of solid density. The purpose of the present phase of the experiment is to develop and validate diagnostic designs, data analysis techniques, and 2-D MHD simulations of the process using the MACH2 code.

  19. The catch state of mollusc catch muscle is established during activation: experiments on skinned fibre preparations of the anterior byssus retractor muscle of Mytilus edulis L. using the myosin inhibitors orthovanadate and blebbistatin.

    Science.gov (United States)

    Andruchov, Oleg; Andruchova, Olena; Galler, Stefan

    2006-11-01

    Catch is a holding state of muscle where tension is maintained passively for long time periods in the absence of stimulation. The catch state becomes obvious after termination of activation; however, it is possible that catch linkages are already established during activation. To investigate this, skinned fibre bundles of the anterior byssus retractor muscle of Mytilus edulis were maximally activated with Ca(2+) and subsequently exposed to 10 mmol l(-1) orthovanadate (V(i)) or 5 mumol l(-1) blebbistatin to inhibit the force-generating myosin head cross-bridges. Repetitive stretches of about 0.1% fibre bundle length were applied to measure stiffness. Inhibitor application depressed force substantially but never resulted in a full relaxation. The remaining force was further decreased by moderate alkalization (change of pH from 6.7 to 7.4) or by cAMP. Furthermore, the stiffness/force ratio was higher during exposure to V(i) or blebbistatin than during partial Ca(2+) activation producing the same submaximal force. The increased stiffness/force ratio was abolished by moderate alkalization or cAMP. Finally, the stretch-induced delayed force increase (stretch activation) disappeared, and the force recovery following a quick release of the fibre length, was substantially reduced when the force was depressed by V(i) or blebbistatin. All these findings suggest that catch linkages are already established during maximal Ca(2+) activation. They seem to exhibit ratchet properties because they allow shortening and resist stretches. In isometric experiments a force decrease is needed to stress the catch linkages in the high resistance direction so that they contribute to force.

  20. Preliminary investigation into sport and exercise psychology consultants' views and experiences of an interprofessional care team approach to sport injury rehabilitation.

    Science.gov (United States)

    Arvinen-Barrow, Monna; Clement, Damien

    2017-01-01

    Sport injury rehabilitation has moved from predominately physical treatment to a more holistic care. However, limited research has explored the views and experiences of those involved in such an approach. The purpose of this study was to preliminarily investigate sport psychology consultants' (SPCs') views and experiences of an interprofessional team approach to sport injury rehabilitation. A cross-sectional online survey previously used with athletic trainers was distributed via a US-based sport/exercise psychology list-serve (N = 1245). A total of 62 (27 men, 35 women, M age 38.2 years, age range: 22-73 years) participants with 10.6 (SD = 9.8) years of experience as an SPC were included in the final analyses. On average, SPCs felt that it was very important (M = 6.6; SD = 0.6) for athletes to have access to an interprofessional care team. Of the sample, 64.5% (n = 40) typically worked as part of an interprofessional care team 44.7% of the time. The SPCs (n = 28; 45.2%) also indicated that the primary treatment providers (e.g., athletic trainer, physical therapist) were typically serving as the primary point person for such teams. Since gaining entry to sport medicine can be an area SPCs struggle with, building effective working relationships with treatment providers can help promote and increase SPCs involvement in providing holistic, interprofessional care to athletes with injuries. To ensure athletes' successful biopsychosocial return to sport, different individuals and professionals should work together for the benefit of the athlete by adopting holistic care during sports injury rehabilitation.

  1. Acquisition and preliminary analysis of multi-channel seismic reflection data, acquired during the oceanographic cruises of the TOMO-ETNA experiment

    Directory of Open Access Journals (Sweden)

    Marco Firetto Carlino

    2016-09-01

    Full Text Available The TOMO-ETNA experiment was performed in the framework of the FP7 “MED-SUV” (MEDiterranean SUpersite Volcanoes in order to gain a detailed geological and structural model of the continental and oceanic crust concerning Etna and Aeolian Islands volcanoes (Sicily, Italy, by means of active and passive seismic exploration methodologies. Among all data collected, some 1410 km of marine multi-channel seismic (MCS reflection profiles were acquired in the Ionian and Tyrrhenian Seas during two of the three oceanographic cruises of the TOMO-ETNA experiment, in July and November 2014, with the aim of shading light to deep, intermediate and shallow stratigraphy and crustal structure of the two above mentioned areas. The MCS sections, targeted to deep exploration, were acquired during the oceanographic cruise on board the R/V “Sarmiento de Gamboa”, using an active seismic source of 16 air-guns, for a total volume of 4340 cu. in., and a 3000 m long, 240-channels digital streamer as receiving system. High-resolution seismic profiles were instead collected through the R/V “Aegaeo”, using two smaller air-guns (overall 270 cu. in. volume and a 96 channels, 300 m long digital streamer. This paper provides a detailed description of the acquisition parameters and main processing steps adopted for the MCS data. Some processed lines are shown and preliminarily interpreted, to highlight the overall good quality and the high potential of the MCS sections collected during the TOMO-ETNA experiment.

  2. 丽江市油橄榄引种栽培试验初报%Preliminary Study on Olive Introduction and Cultivation Experiment in Lijiang

    Institute of Scientific and Technical Information of China (English)

    子桂才

    2011-01-01

    An olive demonstration garden was established, and 14 foreign fine olive varieties have been introduced in 2006 for cultivation trials in Daju town of Lijiang City. Soil preparation, pond digging, fertilizing, planting seedlings during the construction of garden and management and other technical measures after the establishment were described in detail in this article. The results show that Daju town has natural and climatic conditions which are very suitable for olive Cultivation. Olive varieties are self-incompatible, and need pollination between different species. These 14 olive varieties are growing in good condition in the demonstration area with most of them with a survival rate more than 80%. Especially the introduction of ARBEQUINA SELC KORONEIKI in 2006 and the introduction of the varieties in 2009, their growing, fruiting and disease resistant were more prominent. It was suggested to focus on these varieties for cultivation and planting.%在丽江市的大具乡建立油橄榄示范园,并于2006年开始先后引进国外14个油橄榄优良品种进行栽培试验.文中详细阐述了示范园建设中的整地、打塘、施肥、苗木定植以及建园后管理等各项技术措施.结果表明,大具乡的自然、气候条件非常适合油橄榄的栽培;油橄榄品种具有自交不亲和性,需要不同品种之间授粉;14个油橄榄品种在示范区的生长情况良好,大多数成活率都在80%以上,特别是2006年引进的ARBEQUINA SELC和KORONEIKI的生长挂果情况较为突出,2009年引进的鄂植8号、皮肖利和莱星生长、抗病性也非常突出,可重点选育这几个品种作为主栽品种进行推广种植.

  3. Establishment Registration & Device Listing

    Data.gov (United States)

    U.S. Department of Health & Human Services — This searchable database contains establishments (engaged in the manufacture, preparation, propagation, compounding, assembly, or processing of medical devices...

  4. Establishment Registration & Device Listing

    Data.gov (United States)

    U.S. Department of Health & Human Services — This searchable database contains establishments (engaged in the manufacture, preparation, propagation, compounding, assembly, or processing of medical devices...

  5. 渤海海底地震仪探测试验及初步成果%Ocean Bottom Seismometer Experiment and Its Preliminary Results in Bohai Sea

    Institute of Scientific and Technical Information of China (English)

    支鹏遥; 刘保华; 华清峰; 刘晨光; 裴彦良; 郑彦鹏; 郝天珧

    2012-01-01

    利用大容量气枪枪阵震源和海底地震仪在渤海首次开展人工地震深部地球物理探测试验。本次试验布设一条NWW-SEE向垂直构造走向的勘测线,共投放海底地震仪51台,回收成功50台。试验结果和数据分析表明,所使用的枪阵有足够的能量输出,海底地震仪记录震相丰富,可识别到Ps,Pg,PmP,Pn等多种震相。初至波层析成像结果表明,9km以上地层速度结构存在明显的横向不均匀性,渤中地区新生代沉积基底埋深5—6km,结晶基底埋深约9km,郯庐断裂带内存在“u”型下凹的相对低速体并有向下切割的趋势。此次试验是我国在渤海深部探测中的成功示范,有效填补了渤海海域深地震测深数据的空白,为渤海深部地壳结构研究及含油气盆地形成演化研究提供了重要的基础资料。%A deep seismic sounding experiment was carried out for the first time in the Bohai Sea using large volume air-gun array and Ocean Bottom Seismometers (OBSs). Fifty-one OBSs were deployed along a NWW-SEE line perpendicular to the strikes of the regional tectonics and fifty were recovered successfully. Experiment outcome showed the air-gun array used during the experiment had enough power; primary data analysis indicated the OBSs recorded rich seismic phases including Ps, Pg, PmP and Pn. Initial first arrival tomography results show that the shallow layer with depth of less than 9 km has obvious heterogeneity in the lateral direction, the depth of the Ceno- zoic sedimentary basement is 5 ~ 6 km in the Bozhong area and the corresponding crystalline basement depth is a- bout 9 km, and an U-shaped lower velocity body which has the trend to cut through the lower layer can be found in the Tanlu fault zone. This experiment is a successful case of the deep structure exploration in the Bohai Sea. It not only fills in the blanks of deep seismic sounding database, but also supplies fundamental

  6. Preliminary study on magnetic tracking-based planar shape sensing and navigation for flexible surgical robots in transoral surgery: methods and phantom experiments.

    Science.gov (United States)

    Song, Shuang; Zhang, Changchun; Liu, Li; Meng, Max Q-H

    2017-10-05

    Flexible surgical robot can work in confined and complex environments, which makes it a good option for minimally invasive surgery. In order to utilize flexible manipulators in complicated and constrained surgical environments, it is of great significance to monitor the position and shape of the curvilinear manipulator in real time during the procedures. In this paper, we propose a magnetic tracking-based planar shape sensing and navigation system for flexible surgical robots in the transoral surgery. The system can provide the real-time tip position and shape information of the robot during the operation. We use wire-driven flexible robot to serve as the manipulator. It has three degrees of freedom. A permanent magnet is mounted at the distal end of the robot. Its magnetic field can be sensed with a magnetic sensor array. Therefore, position and orientation of the tip can be estimated utilizing a tracking method. A shape sensing algorithm is then carried out to estimate the real-time shape based on the tip pose. With the tip pose and shape display in the 3D reconstructed CT model, navigation can be achieved. Using the proposed system, we carried out planar navigation experiments on a skull phantom to touch three different target positions under the navigation of the skull display interface. During the experiments, the real-time shape has been well monitored and distance errors between the robot tip and the targets in the skull have been recorded. The mean navigation error is [Formula: see text] mm, while the maximum error is 3.2 mm. The proposed method provides the advantages that no sensors are needed to mount on the robot and no line-of-sight problem. Experimental results verified the feasibility of the proposed method.

  7. Preliminary Results of a U.S. Deep South Modeling Experiment Using NASA SPoRT Initialization Datasets for Operational National Weather Service Local Model Runs

    Science.gov (United States)

    Wood, Lance; Medlin, Jeffrey M.; Case, Jon

    2012-01-01

    A joint collaborative modeling effort among the NWS offices in Mobile, AL, and Houston, TX, and NASA Short-term Prediction Research and Transition (SPoRT) Center began during the 2011-2012 cold season, and continued into the 2012 warm season. The focus was on two frequent U.S. Deep South forecast challenges: the initiation of deep convection during the warm season; and heavy precipitation during the cold season. We wanted to examine the impact of certain NASA produced products on the Weather Research and Forecasting Environmental Modeling System in improving the model representation of mesoscale boundaries such as the local sea-, bay- and land-breezes (which often leads to warm season convective initiation); and improving the model representation of slow moving, or quasi-stationary frontal boundaries (which focus cold season storm cell training and heavy precipitation). The NASA products were: the 4-km Land Information System, a 1-km sea surface temperature analysis, and a 4-km greenness vegetation fraction analysis. Similar domains were established over the southeast Texas and Alabama coastlines, each with an outer grid with a 9 km spacing and an inner nest with a 3 km grid spacing. The model was run at each NWS office once per day out to 24 hours from 0600 UTC, using the NCEP Global Forecast System for initial and boundary conditions. Control runs without the NASA products were made at the NASA SPoRT Center. The NCAR Model Evaluation Tools verification package was used to evaluate both the positive and negative impacts of the NASA products on the model forecasts. Select case studies will be presented to highlight the influence of the products.

  8. X-ray spectrophotometer SphinX and particle spectrometer STEP-F of the satellite experiment CORONAS-PHOTON. Preliminary results of the joint data analysis

    Science.gov (United States)

    Dudnik, O. V.; Podgorski, P.; Sylwester, J.; Gburek, S.; Kowalinski, M.; Siarkowski, M.; Plocieniak, S.; Bakala, J.

    2012-04-01

    A joint analysis is carried out of data obtained with the help of the solar X-ray SphinX spectrophotometer and the electron and proton satellite telescope STEP-F in May 2009 in the course of the scientific space experiment CORONAS-PHOTON. In order to determine the energies and particle types, in the analysis of spectrophotometer records data are used on the intensities of electrons, protons, and secondary γ-radiation, obtained by the STEP-F telescope, which was located in close proximity to the SphinX spectrophotometer. The identical reaction of both instruments is noted at the intersection of regions of the Brazilian magnetic anomaly and the Earth's radiation belts. It is shown that large area photodiodes, serving as sensors of the X-ray spectrometer, reliably record electron fluxes of low and intermediate energies, as well as fluxes of the secondary gamma radiation from construction materials of detector modules, the TESIS instrument complex, and the spacecraft itself. The dynamics of electron fluxes, recorded by the SphinX spectrophotometer in the vicinity of a weak geomagnetic storm, supplements the information about the processes of radial diffusion of electrons, which was studied using the STEP-F telescope.

  9. Development and Preliminary Testing of a Framework to Evaluate Patients' Experiences of the Fundamentals of Care: A Secondary Analysis of Three Stroke Survivor Narratives

    Directory of Open Access Journals (Sweden)

    Alison L. Kitson

    2013-01-01

    Full Text Available Aim. To develop and test a framework describing the interrelationship of three key dimensions (physical, psychosocial, and relational in the provision of the fundamentals of care to patients. Background. There are few conceptual frameworks to help healthcare staff, particularly nurses, know how to provide direct care around fundamental needs such as eating, drinking, and going to the toilet. Design. Deductive development of a conceptual framework and qualitative analysis of secondary interview data. Method. Framework development followed by a secondary in-depth analysis of primary narrative interview data from three stroke survivors. Results. Using the physical, psychosocial and relational dimensions to develop a conceptual framework, it was possible to identify a number of “archetypes” or scenarios that could explain stroke survivors’ positive experiences of their care. Factors contributing to suboptimal care were also identified. Conclusions. This way of thinking about how the fundamentals of care are experienced by patients may help to elucidate the complex processes involved around providing high quality fundamentals of care. This analysis illustrates the multiple dimensions at play. However, more systematic investigation is required with further refining and testing with wider healthcare user groups. The framework has potential to be used as a predictive, evaluative, and explanatory tool.

  10. Concerning the preliminary results of space experiment with the seeds of rare plants (on the boad of BION-M No.1)

    Science.gov (United States)

    Gorelov, Yury; Kurganskaya, Lubov; Ilyin, Vyacheslav; Ruzaeva, Irina; Rozno, Svetlana; Kavelenova, Ludmila

    The problem of native flora plants conservation appears today as one of the most actual for humanity. The wide spreading natural ecosystems degradation results in the status changes for formerly common species to rare, endangered or extincted ones. That is why the complex of biological diversity conservation measures must be used including ex situ and in situ forms. Last years the seed banks (special seed collections in controlled conditions, including temperature below zero) and field banks (special alive plants collections) were created in many countries taking in mind the future of humanity. The seed banks as long-term depositories can be placed on the space stations where the threat of earth catastrophes is removed. But we must make it clear how the complex of space flight factors effects upon the seed quality and germination and plants development from “cosmic” seeds. For instance, the action of residual ionizing radiation into space apparatus on plant seeds can alter its vitality maybe by the growth of free radicals pool in molecular and subcellular level. The unknown level of such action permits us to propose wide diapason of effects from the absence of any changes to the stimulation of vital activity, decrease of it, mutagenesis and maybe the death of seeds. Only the experiments that begin in space and continue on the Earth can show us the effect of space flight factors complex on plant seeds. Here we describe the first results of experiment held on the board of space apparatus “Bion-M” No1. Totally 79 experiments were included to the program of “Bion-M”, among them the experiment “Biocont-BS”. The equipment for it was prepared by Central Scientific Research Institute of Machine-building; the seed material was selected and prepared by the Botanical Garden of Samara State University. The equipment with seeds was into space apparatus, which working orbit was average 575 km and the flight lasted for 30 days. The seed samples of 9 rare plants

  11. Preliminary simulations of planned experiments to study the impact of trace gases on the capacity of the Weyburn-Midale field to store carbon dioxide

    Energy Technology Data Exchange (ETDEWEB)

    Carroll, S; Hao, Y

    2009-11-13

    oxidized to H{sub 2}SO{sub 4} causing enhanced dissolution of carbonate minerals and some sulfate mineral precipitation. Low pH results in higher mineral solubility and faster dissolution rates and is thought to enhance porosity and permeability near the injection well when trace amounts of SO{sub 2} is injected with CO{sub 2}. The impact of H{sub 2}S on storage reservoir performance appears to more subtle. Knauss et al (2005) report no significant impacts of injection of CO{sub 2} gas streams with and without H{sub 2}S (1 M Pascal H{sub 2}S + 8.4 M Pascal CO{sub 2}) in simulations of CO{sub 2} storage in the Frio sandstone formation. Geochemical reactions for H{sub 2}S impurities include enhance field alkalinity and reaction with iron bearing minerals that may delay breakthrough of H{sub 2}S relative to CO{sub 2}. Emberley et al. (2005) report that half of the alkalinity measured at monitoring wells at the Weyburn-Midale field is due to HS{sup -}. Schoonen and Xu (2004) report that H{sub 2}S can be sequestered as pyrite in sandstones and carbonates by dissolving iron hydroxides and iron-bearing clays. Similarly, Gunter et al (2000) propose the that siderite converts to iron sulfides when it is reacted with H{sub 2}S. The geochemical reactions between H{sub 2}S and iron bearing minerals together with the high solubility of H{sub 2}S relative to CO{sub 2} may contribute to the delayed break though of H{sub 2}S in experiments. A few core flood experiments have shown that the injection of supercritical CO{sub 2} into carbonate aquifers has the potential to significantly alter the porosity in the absence of trace gases such as SO{sub 2} and H{sub 2}S. Luquot and Gouze (2009) documented a 2% porosity increase in carbonate cores when rock-water interactions were transport limited and solution concentrations were closer to equilibrium and a 4% porosity increase when rock-water interactions were reaction limited and solution compositions were further from equilibrium. Similarly Le

  12. Preliminary report on potato cultivation experiment mulched by different materials%马铃薯不同材料覆盖栽培试验初报

    Institute of Scientific and Technical Information of China (English)

    廖义利; 郑莉

    2015-01-01

    A cultiVation experiment on potato mulched by different materials was carried out. The results showed that,com-pared with traditional non-mulching culture,using plastic film mulching and straw mulching on ridge surface could increase yield and efficiency in field cultiVation. Among them,black plastic film mulching had the adVantages of raising soil tempera-ture,cold-proof,conserVing water and fertilizer,non-weeding,saVing labor,high rate of big tuber,obVious effect of increas-ing yield and efficiency,and so on.%进行马铃薯不同材料覆盖栽培试验,结果表明:畦面采用地膜和稻草覆盖的比传统无覆盖栽培增产增效,其中黑色地膜覆盖处理能够提高土温、防寒、保水、保肥、免除草、节约劳力、大薯率高,增产增效最为明显.

  13. AgRISTARS: Foreign commodity production forecasting. Minutes of the annual formal project manager's review, including preliminary technical review reports of FY80 experiments. [wheat/barley and corn/soybean experiments

    Science.gov (United States)

    1980-01-01

    The U.S./Canada wheat/barley exploratory experiment is discussed with emphasis on labeling, machine processing using P1A, and the crop calendar. Classification and the simulated aggregation test used in the U.S. corn/soybean exploratory experiment are also considered. Topics covered regarding the foreign commodity production forecasting project include: (1) the acquisition, handling, and processing of both U.S. and foreign agricultural data, as well as meteorological data. The accuracy assessment methodology, multicrop sampling and aggregation technology development, frame development, the yield project interface, and classification for area estimation are also examined.

  14. Negative childhood experiences alter a prefrontal-insular-motor cortical network in healthy adults: A preliminary multimodal rsfMRI-fMRI-MRS-dMRI study

    Science.gov (United States)

    Duncan, Niall W.; Hayes, Dave J.; Wiebking, Christine; Tiret, Brice; Pietruska, Karin; Chen, David Q.; Rainville, Pierre; Marjańska, Malgorzata; Mohammid, Omar; Doyon, Julien; Hodaie, Mojgan; Northoff, Georg

    2016-01-01

    Research in humans and animals has shown that negative childhood experiences (NCE) can have long-term effects on the structure and function of the brain. Alterations have been noted in grey and white matter, in the brain’s resting state, on the glutamatergic system, and on neural and behavioural responses to aversive stimuli. These effects can be linked to psychiatric disorder such as depression and anxiety disorders that are influenced by excessive exposure to early life stressors. The aim of the current study was to investigate the effect of NCEs on these systems. Resting state functional MRI (rsfMRI), aversion task fMRI, glutamate magnetic resonance spectroscopy (MRS), and diffusion magnetic resonance imaging (dMRI) were combined with the Childhood Trauma Questionnaire (CTQ) in healthy subjects to examine the impact of NCEs on the brain. Low CTQ scores, a measure of NCEs, were related to higher resting state glutamate levels and higher resting state entropy in the medial prefrontal cortex (mPFC). CTQ scores, mPFC glutamate and entropy, correlated with neural BOLD responses to the anticipation of aversive stimuli in regions throughout the aversion-related network, with strong correlations between all measures in the motor cortex and left insula. Structural connectivity strength, measured using mean fractional anisotropy, between the mPFC and left insula correlated to aversion-related signal changes in the motor cortex. These findings highlight the impact of NCEs on multiple inter-related brain systems. In particular, they highlight the role of a prefrontal-insular-motor cortical network in the processing and responsivity to aversive stimuli and its potential adaptability by NCEs. PMID:26287448

  15. Preliminary ECLSS waste water model

    Science.gov (United States)

    Carter, Donald L.; Holder, Donald W., Jr.; Alexander, Kevin; Shaw, R. G.; Hayase, John K.

    1991-01-01

    A preliminary waste water model for input to the Space Station Freedom (SSF) Environmental Control and Life Support System (ECLSS) Water Processor (WP) has been generated for design purposes. Data have been compiled from various ECLSS tests and flight sample analyses. A discussion of the characterization of the waste streams comprising the model is presented, along with a discussion of the waste water model and the rationale for the inclusion of contaminants in their respective concentrations. The major objective is to establish a methodology for the development of a waste water model and to present the current state of that model.

  16. Preliminary ECLSS waste water model

    Science.gov (United States)

    Carter, Donald L.; Holder, Donald W., Jr.; Alexander, Kevin; Shaw, R. G.; Hayase, John K.

    1991-01-01

    A preliminary waste water model for input to the Space Station Freedom (SSF) Environmental Control and Life Support System (ECLSS) Water Processor (WP) has been generated for design purposes. Data have been compiled from various ECLSS tests and flight sample analyses. A discussion of the characterization of the waste streams comprising the model is presented, along with a discussion of the waste water model and the rationale for the inclusion of contaminants in their respective concentrations. The major objective is to establish a methodology for the development of a waste water model and to present the current state of that model.

  17. A Preliminary Exploration on the Application of Senior Physics Experiment Teaching Based on DIS Experiment Technology%基于DIS实验技术的高中物理实验教学应用初探

    Institute of Scientific and Technical Information of China (English)

    杨清泉

    2016-01-01

    After introduced into senior physics experiment teach-ing, digital information technology represented by DIS experiment technology, with its convenient operation process, powerful data processing and flexible and diversified designs, has brought brand new vitalities to senior physics teaching under the new sit-uation and has been continuously promoting the digitalization process of senior physics experiment teaching. Based on the in-troduction of the definitions relevant to DIS experiment, its ne-cessity and application principles, this paper puts forward corre-sponding application strategies.%以DIS实验技术为代表的数字化信息技术被引入到高中物理实验教学中后以其方便的操作流程、强大的数据处理能力以及灵活多样的设计为新形势下的高中物理教学注入了全新的生机和活力,不断推动高中物理实验教学的数字化进程。本文将在介绍DIS实验的相关概念、必要性及运用原则的基础之上,提出相应的应用策略。

  18. Robotic-assisted transperitoneal nephron-sparing surgery for small renal masses with associated surgical procedures: surgical technique and preliminary experience.

    Science.gov (United States)

    Ceccarelli, Graziano; Codacci-Pisanelli, Massimo; Patriti, Alberto; Ceribelli, Cecilia; Biancafarina, Alessia; Casciola, Luciano

    2013-09-01

    . Challenging situations are hilar, posterior or intraparenchymal tumour localization. In our experience, robotic technology made possible a safe minimally invasive management, including vascular clamping, tumour resection and parenchyma reconstruction.

  19. Blood Establishment Registration Database

    Data.gov (United States)

    U.S. Department of Health & Human Services — This application provides information for active, inactive, and pre-registered firms. Query options are by FEI, Applicant Name, Establishment Name, Other Names,...

  20. Braquiterapia com rutênio-106 em melanomas uveais - resultados preliminares: experiência uni-institucional Ruthenium-106 brachytherapy for uveal melanomas - preliminary results: a single institutional experience

    Directory of Open Access Journals (Sweden)

    Rodrigo Souza Dias

    2007-04-01

    associated brachytherapy and transpupillary thermotherapy. A significant tumor height reduction was observed after treatment. No patient was submitted to enucleation. CONCLUSION: Our preliminary results show that ruthenium-106 brachytherapy is an appropriate method for conservative treatment of patients with uveal melanomas in terms of local management, ocular and visual acuity preservation with an acceptable complications incidence rate.

  1. 机器人辅助腹腔镜肝切除术的经验初探%Preliminary experience of robotic-assisted laparoscopic liver resection

    Institute of Scientific and Technical Information of China (English)

    肖乐; 李建伟; 郭鹏; 王小军; 别平; 郑树国

    2016-01-01

    Objective To summarize the preminiary experience of robotic-assisted laparoscopic liver resection. Methods The clinical data of 60 consecutive patients who underwent robot-assisted laparosopic liver resections for liver diseases at our institute from Jan 2010 to Jan 2016 were retrospectively analyzed. Results There were 57 cases who received successful robotic-assisted laparoscopic hepatectomy and 3 cases (5.0%) converted to open surgery. Operative time was (353±121) min. Intraoperative blood loss was(390±287) mL with transfusion rate 11.7%. Postoperative complications occurred in 15 cases (25.0%) and complications with Clavien≥3b accounted for 3.3%. Hospital stay was (9.1±3.3) days. The stone remove rate was 100%(22 cases) including 21 cases with hepatolithiasis(95.5%) removed intraoperatively and 1 case with residual stone successfully removed using choledochoscopy via a T-tube sinus postoperatively. No death occurred during perioperative period. All cases were followed-up for (18.8±12.0)(2-50)months. During the follow-up period,7 in 24 cases with cancer were found recurrence and 17 cases without. Among the cases with recurrence,4 cases died and 3 survived with tumor. Two in 22 cases with hepatolithiasis recurred and received reoperation and the other 2 cases experienced chronic cholangitis and resolved after medical treatment. Conclusions Robotic-assisted laparoscopic hepatectomy is safe, feasible and efficacious for selected patients with advantages of minimally invasive surgery.%目的:总结机器人辅助腹腔镜肝切除的初步经验。方法:回顾性分析我院2010年1月至2016年1月连续60例达芬奇机器人辅助腹腔镜肝切除术病人的临床资料。结果:60例中57例完成机器人辅助腹腔镜肝切除术,3例中转开腹,中转率为5.0%。平均手术时间(353±121) min,术中失血量(390±287) mL,术中输血率11.7%,术后并发症发生率25.0%(15例),其中3b级以上发生率3.3%

  2. 单切口改良Nuss手术矫治儿童漏斗胸%Modified Single-incision Nuss Procedure for Pectus Excavatum in Children: Preliminary Experience

    Institute of Scientific and Technical Information of China (English)

    陶麒麟; 贾兵; 闫宪刚; 张惠锋

    2016-01-01

    目的 总结单切口改良Nuss手术矫治儿童漏斗胸的手术方法、临床经验及早期效果. 方法 2013年5月~2014年12月,选择性采用单切口改良Nuss手术治疗65例儿童漏斗胸,平均年龄5 .3岁( 4~12岁). 根据Park分型,对称型41例,不对称型24例. 术前胸部CT测量Haller指数3.21~12.54(4.65 ±1.56). 手术采用新型钛合金支架,支架前端为圆钝收窄的穿通段,具有穿通胸骨后及肋间隙的功能. 手术仅做一处右侧胸壁2 cm横行小切口,置入支架及胸腔镜,已塑型的支架凸面朝下由右侧肋弓最高点经胸骨最低点至左侧肋弓最高点穿出,支架翻转后前端置于左侧胸壁皮下,皮下保留2~3 cm. 右侧切口内放入固定片,以螺丝与支架固定. 根据术后Haller指数及随访结果评价手术效果. 结果 全组手术顺利,采用胸腔镜辅助手术63例. 手术时间19~45 min,平均26 min. 全组均植入1根矫形支架. 术后并发气胸1例、胸腔积液1例、切口感染1例. 术后3个月胸部CT测量Haller指数2.21~3.12(2.48 ±0.36),术后6个月2.18~3.24(2.45 ±0.32),与术前相比均有显著差异(t=6.286、6.487,P=0.000、0.000). 所有患儿随访9~28个月,矫形效果满意,无支架移位、获得性脊柱侧弯、金属过敏等并发症,未出现支架前端横向移位脱入胸腔. 结论 在低龄以及稍大龄轻症漏斗胸患儿中使用新型单孔钛合金支架施行单切口改良Nuss手术,安全可行,矫形效果满意,而且切口更美观,操作更简化,手术更微创.%Objective To summarize the clinical experience and evaluate the early outcomes of modified single-incision Nuss procedure for pectus excavatum in children. Methods A total of 65 children with pectus excavatum who were chosen to undergo modified single-incision Nuss procedure from May 2013 to December 2014 were reviewed retrospectively.Patients' age ranged from 4 to 12 years old (mean, 5.3 years old).According to the Park classification, there were

  3. Establish and Manage Jurisdiction-wide Traffic Monitoring Systems: North American Experiences%管辖范围内的交通监控系统的建立和管理:北美经验

    Institute of Scientific and Technical Information of China (English)

    钟鸣; 刘国新

    2007-01-01

    With the rapid motorization process in China, an increasingly complicated highway transportation system has been developed. Reliable national and provincial traffic monitoring systems are becoming necessary. A review of experiences from developed countries in North America can be helpful for highway administrations and agencies to design and implement effective and efficient traffic monitoring systems. Highway agencies in North America have over time developed "standard" traffic monitoring systems based on guidelines from the Federal Highway Administration (FHWA), the American Association of State Highway and Transportation Officials (AASHTO), and the American Society for Testing and Materials (ASTM). Common practices are adopted based on analyses of system accuracy, reliability, and cost-effectiveness. The common practices can produce equivalent and comparable traffic summary statistics, which are able to support sensible decision-makings at all aspects of highway transportation. The experiences of highway agencies, current practices, and related guidelines in North America are therefore presented first. Principles for guiding development and operation of traffic data programs are then summarized and reviewed. Existing problems and active research for traffic monitoring practices and standards are also identified and discussed. It is believed that the reviewed experiences, guidelines and principles will be helpful for China to establish effective and common-practice based "standard" traffic monitoring systems.%随着中国机动化进程的加快,高速公路运输系统日益复杂化,建立可靠的国家和地方交通监控系统已成为必需.回顾北美发达国家的经验对于高速公路的管理和设计部门设计及实施有效的交通监控系统是有益的.在联邦高速公路管理局(FHWA),美国州公路和运输官员协会(AASHTO)以及美国材料与试验协会(ASTM)的指导方针下,北美高速公路部门开发了一套"标准的"

  4. Earth Sciences Requirements for the Information Sciences Experiment System

    Science.gov (United States)

    Bowker, David E. (Editor); Katzberg, Steve J. (Editor); Wilson, R. Gale (Editor)

    1990-01-01

    The purpose of the workshop was to further explore and define the earth sciences requirements for the Information Sciences Experiment System (ISES), a proposed onboard data processor with real-time communications capability intended to support the Earth Observing System (Eos). A review of representative Eos instrument types is given and a preliminary set of real-time data needs has been established. An executive summary is included.

  5. Establishing the Intermediate Unit.

    Science.gov (United States)

    Pennsylvania State Dept. of Education, Harrisburg.

    The State of Pennsylvania Act 102 establishes a system of 29 intermediate units, creates intermediate unit boards of directors, spells out their duties and functions, and provides a system of financing their operations. This handbook has been prepared by the Pennsylvania Department of Education to provide intermediate unit boards of directors,…

  6. Secular Religious Establishment

    DEFF Research Database (Denmark)

    Lægaard, Sune

    2013-01-01

    Secularism as a political doctrine claims that religion and politics should be separated. The compatibility question is whether secularism can accept some forms of religious establishment in the form of institutional linkages between state and organised religion. I argue that the answer to the co...

  7. Amphibole ceramics: conceptual development and preliminary experiments

    Energy Technology Data Exchange (ETDEWEB)

    Lauf, R.J.

    1985-08-01

    Certain natural silicate minerals, commonly called jade, are well known for their resistance to brittle fracture. One type of jade, nephrite, is a compacted form of the amphibole mineral series tremolite-actinolite. Nephrite is tough because the naturally acicular crystal habit of these amphibole minerals produces an interwoven fibrous microstructure that impedes crack propagation. Object of this work was to duplicate the fibrous microstructure of nephrite by pulverizing natural tremolite or actinolite and then compacting it by hot pressing to form a dense body. Two other materials were also investigated, namely, clinochrysotile (serpentine asbestos) and synthetic fluor-tremolite. For each material, the milling characteristics and densification were studied. The resulting microstructures were characterized, and fracture toughness was measured for a limited number of samples. The most ''fibrous'' microstructure was obtained by hot pressing clinochrysotile 15 min a 1000/sup 0/C. Actinolite, hot pressed 15 min at 1100/sup 0/C, had a critical fracture toughness K/sub IC/ = 4.5 MPa m/sup 1/2/, which compares favorably with the toughness of nephrite jade (K/sub IC/ = 3.6). Decomposition of tremolite and actinolite to more stable phases occurred to some degree during hot pressing. Results suggest that hot isostatic pressing at high water vapor pressure should yield a dense product without causing amphibole decomposition. 28 figs., 7 tabs.

  8. Mariner 9 science experiments - Preliminary results.

    Science.gov (United States)

    Steinbacher, R. H.; Kliore, A.; Lorell, J.; Hipsher, H.; Barth, C. A.; Masursky, H.; Muench, G.; Pearl, J.; Smith, B.

    1972-01-01

    On the basis of data provided by the IR interferometer spectrometer on the Mariner 9 spacecraft, it is suggested that the composition of the Martian dust corresponds approximately to that of rocks of intermediate silicon dioxide content. The large dynamical pole flattening obtained from satellite observations has been confirmed by the Mariner 9 data.

  9. Preliminary experience with dexmedetomidine in neonatal anesthesia

    Directory of Open Access Journals (Sweden)

    Özcengiz Dilek

    2011-01-01

    Conclusion: Dexmedetomidine 1 μgkg -1 followed by maintenance dose of 0.5 μg kg -1 h -1 as an adjacent to sevoflurane anaesthesia in new born undergoing laparatomy provides haemodynamic stability during heightened surgical stimulate.

  10. Establishing the effectiveness, cost-effectiveness and student experience of a Simulation-based education Training program On the Prevention of Falls (STOP-Falls) among hospitalised inpatients: a protocol for a randomised controlled trial.

    Science.gov (United States)

    Williams, Cylie; Bowles, Kelly-Ann; Kiegaldie, Debra; Maloney, Stephen; Nestel, Debra; Kaplonyi, Jessica; Haines, Terry

    2016-06-02

    Simulation-based education (SBE) is now commonly used across health professional disciplines to teach a range of skills. The evidence base supporting the effectiveness of this approach for improving patient health outcomes is relatively narrow, focused mainly on the development of procedural skills. However, there are other simulation approaches used to support non-procedure specific skills that are in need of further investigation. This cluster, cross-over randomised controlled trial with a concurrent economic evaluation (cost per fall prevented) trial will evaluate the effectiveness, cost-effectiveness and student experience of health professional students undertaking simulation training for the prevention of falls among hospitalised inpatients. This research will target the students within the established undergraduate student placements of Monash University medicine, nursing and allied health across Peninsula Health acute and subacute inpatient wards. The intervention will train the students in how to provide the Safe Recovery program, the only single intervention approach demonstrated to reduce falls in hospitals. This will involve redevelopment of the Safe Recovery program into a one-to-many participant SBE program, so that groups of students learn the communication skills and falls prevention knowledge necessary for delivery of the program. The primary outcome of this research will be patient falls across participating inpatient wards, with secondary outcomes including student satisfaction with the SBE and knowledge gain, ward-level practice change and cost of acute/rehabilitation care for each patient measured using clinical costing data. The Human Research Ethics Committees of Peninsula Health (LRR/15/PH/11) and Monash University (CF15/3523-2015001384) have approved this research. The participant information and consent forms provide information on privacy, storage of results and dissemination. Registration of this trial has been completed with the

  11. Multi-GNSS Orbit and Clock Combination: Preliminary Results

    Science.gov (United States)

    Fritsche, Mathias

    2016-04-01

    In the framework of the Multi-GNSS Experiment (MGEX) a number of Analysis Centers (ACs) extended their software capabilities to process signals from the BeiDou, Galileo, and QZSS systems in addition to the well established systems GPS and GLONASS. Currently, the MGEX product portfolio covers precise satellite orbits and clocks, receiver clocks, signal biases, and Earth rotation parameters generated by the individual ACs. This presentation will provide an overview on the available AC-specific MGEX products. In addition, an introduction to a multi-GNSS orbit and clock combination procedure will be given. Finally, preliminary results from that multi-GNSS combination including a comparison with corresponding operational IGS products will be reported along with a discussion of the results.

  12. Secular Religious Establishment

    DEFF Research Database (Denmark)

    Lægaard, Sune

    2013-01-01

    Secularism as a political doctrine claims that religion and politics should be separated. The compatibility question is whether secularism can accept some forms of religious establishment in the form of institutional linkages between state and organised religion. I argue that the answer...... to the compatibility question is not obvious and requires a systematic analysis of secularism. Based on a distinction between a general concept and specific conceptions of secularism I offer a general structure for conceptions of secularism that incorporates both a) basic values, e.g. political equality and freedom...... of conscience, b) intermediate political principles of separation, e.g. rights to religious liberty, and c) derived normative prescriptions, e.g. that an established church is unacceptable. I illustrate the structure using the conceptions of secularism advocated by Robert Audi and by Charles Taylor and Jocelyn...

  13. Study on Establishment of Experiment for Undergraduate Major of Applied Chemistry in Agricultural University%农业院校应用化学专业实验课程的设立与思考

    Institute of Scientific and Technical Information of China (English)

    舒绪刚; 阎杰; 宋光泉; 蒋旭红

    2011-01-01

    应用化学专业基础实验课程体系的改革与思考以我校应用化学专业为研究对象,整合四大化学的基础实验,提出十项试验技术,探讨了该专业的实验课程体系的建设与教学方式的改革。%On the base of applied chemistry specialty in the university,the construction on its experimental course system was discussed focusing on ten modules,At the same time,the process and method in detail for the reform were also preliminary presented.

  14. Improvement of technical training of sportswomen in rhythmic gymnastics by means of acrobatics at the stage of preliminary basic preparation

    Directory of Open Access Journals (Sweden)

    Petro Kyzim

    2016-10-01

    Full Text Available Purpose: to prove experimentally the technique of improvement of technical training of sportswomen in rhythmic gymnastics by means of acrobatics at the stage of preliminary basic preparation. Material & Methods: the following methods of the research were used: analysis and synthesis of references, pedagogical observations, pedagogical testing, pedagogical experiment, method of expert assessment (qualimetry, methods of mathematical statistics. Results: the level of technical skill of performance of pre-acrobatic elements by sportswomen of rhythmic gymnastics before carrying out the pedagogical experiment is determined. The dynamics of indicators of the level of technical preparedness of sportswomen of rhythmic gymnastics is defined. Conclusions: it is established that additional resources of acrobatics influence significantly the level of technical preparedness of sportswomen of rhythmic gymnastics at the stage of preliminary basic preparation.

  15. 2016 TRI Preliminary Dataset

    Science.gov (United States)

    The TRI preliminary dataset includes the most current TRI data available and reflects toxic chemical releases and pollution prevention activities that occurred at TRI facilities during the 2016 calendar year.

  16. Guidelines of Decommissioning Schedule Establishment

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Jae Yong; Yun, Taesik; Kim, Younggook; Kim, Hee-Geun [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    Decommissioning has recently become an issue highlighted in Korea due to the Permanent Shutdown (PS) of Kori-1 plant. Since Korea Hydro and Nuclear Power (KHNP) Company decided the PS of Kori-1 instead of further continued operation, Kori-1 will be the first decommissioning plant of the commercial reactors in Korea. Korean regulatory authority demands Initial Decommissioning Plan (IDP) for all the plants in operation and under construction. In addition, decommissioning should be considered for the completion of the life cycle of NPPs. To date, Korea has no experience regarding decommissioning of the commercial reactor and a lot of uncertainties will be expected due to its site-specific factors. However, optimized decommissioning process schedule must be indispensable in the safety and economic efficiency of the project. Differed from USA, Korea has no experience and know-hows of the operation and site management for decommissioning. Hence, in Korea, establishment of decommissioning schedule has to give more weight to safety than precedent cases. More economical and rational schedule will be composed by collecting and analyzing the experience data and site-specific data and information as the decommissioning progresses. In a long-range outlook, KHNP having capability of NPP decommissioning will try to decommissioning business in Korea and foreign countries.

  17. A PRELIMINARY STUDY OF EXPERT SYSTEM FOR MINING UNDER STRUCTURES

    Institute of Scientific and Technical Information of China (English)

    吴侃; 何国清; 曹立明

    1991-01-01

    The expert system MUST (Mining Under Structures) shown in this paper and established by the authors is a preliminary expert system to solve the policy-making problems formining under structures by means of computers instead of humanbeing. Based on the experience of relative experts,the authors established a knowledge base about the minings under structures ,researched into reasonable method to simulate thinking processes of human experts when they are solvin8 the problems, established the network of an expert system and named it'MUST system'MUST system uses the method of the structural system analysis approach. A kind of methods of Turbo Prolog and Fortran 77 language alternations is designed to meet the needs of exchange information within the MUST system. Based on this kind of methods MUST system has been constructed and realised on IBM-PC computer. For verifying the correctness. suitability and reliablity of MUST system,some practical examples of minings under structures were tentatively solved using MUST system ,whose results are satisfactory.

  18. Establishment, identification and preliminary phenotype of mouse model of specific Smad4 conditional gene knockout in lens ectoderm%条件性 Sm ad4基因敲除鼠模型的建立和鉴定及初步表型

    Institute of Scientific and Technical Information of China (English)

    刘瑛; 林丁

    2014-01-01

    analysis by establishing the mouse model of specific Smad4 conditional gene knockout in ocular tissue by Cre/LoxP system of this kind of mouse model. METHODS: Mouse of specific Smad4 conditional knockout in lens ectoderm ( Le-Cre; Samd4fl/fl or also called mutant mouse) was obtained by mating the Pax6 promoter-driven Cre transgenic mouse ( Le-Cre ) with Smad4 wildtype mouse ( Smad4 fl/fl).To confirm that Smad4 has been conditionally inactivated only in the specific tissue of ectoderm such as lens, cornea and ectoderm of the eyelids so on.A series of assays were carried out to reveal the validity and specificity of Smad4 gene knockout at molecular and cellular levels, including genotyping by PCR, detection of green fluorescence protein ( GFP) in specific tissue and Smad4 protein.The expression of Le-Cre from Lacz staining using ROSA26 reporter genes in specific ocular tissue of mice can be visualized.Preliminary phenotype of mutant mouse was also observed. RESULTS: As early as around E10.0, strong GFP expression was observed in the embryonic lens and periorbital ectoderm of the mice, which showed Le-Cre was expressed in specific target tissue. Through genotyping for Smad4, Cre and Rosa genes, the mice were determined if they have carried Cre, Smad4 allele or Rosa reporter gene.It was further confirmed by lens-sampled genotyping that Smad4 gene was removed from some specific tissue such as lens.The spatial-temporal expression and tissue specificity of Le-Cre recombinase was also revealed by LacZ staining of Rosa; Le-Cre double transgenic mouse. According to Immunohistochemical staining, Smad4 was widely expressed in normal embryonic eyes, mainly appearing in the cytoplasm at the early embryonic stage and were transferred to nucleus with gestation developing, while in mutant embryonic eyes, Smad4 was void of expression in Cre-expressed tissues. It was observed that Smad4 mutant mouse could survive the conditional gene knockout.But those mice showed abnormal appearance such

  19. Establishing effective working relationships.

    Science.gov (United States)

    Houghton, Trish

    2016-02-24

    This article, the second in a series of 11, provides support and offers advice to new and existing mentors and practice teachers to enable them to progress in their role and develop a portfolio of evidence. In particular, the article discusses how to establish effective working relationships and emphasises the importance of the student-mentor or student-practice teacher relationship. It examines the essential qualities, attributes and characteristics of an effective mentor or practice teacher. The article provides learning activities and suggests ways in which mentors and practice teachers can undertake various self-assessments, enabling them to gather relevant evidence to demonstrate how they can meet and maintain the requirements for these roles as stipulated by the Nursing and Midwifery Council.

  20. The Practice and Experience of Human Resource in Establishing Second Grade Class A Hospital/CHEN Xiao-lian etc.%二级甲等医院创建中人力资源的做法与体会

    Institute of Scientific and Technical Information of China (English)

    陈孝莲; 杨永春; 鲍继海; 张红军; 敖朝光

    2012-01-01

      医院等级是医院综合竞争力的体现,创建等级医院是医改的需要,是医院可持续发展的需要。本文通过介绍四川省遂宁市某医院成功创建二级甲等医院中人力资源的具体实践,指出人力资源配置合理与否是衡量一所医院发展快慢的标准之一,通过等级医院创建工作可促进人力资源管理水平全面提升。%  Hospital grade is the embodiment of the hospital comprehensive competitiveness, establishing hospital grade is the need for health care reform, and is the need of the hospital sustainable development. In this paper, through introducing the human resource specific practice in successful establishing second grade class A hospital in a hospital of Suining city, Sichuan Province, pointed out that the reasonable alocation of human resources is one of the standard to measure one hospital development speed level, established hospital grade can promote the level of human resources management to enhance.

  1. Establishing lunar resource viability

    Science.gov (United States)

    Carpenter, J.; Fisackerly, R.; Houdou, B.

    2016-11-01

    Recent research has highlighted the potential of lunar resources as an important element of space exploration but their viability has not been demonstrated. Establishing whether or not they can be considered in future plans is a multidisciplinary effort, requiring scientific expertise and delivering scientific results. To this end various space agencies and private entities are looking to lunar resources, extracted and processed in situ, as a potentially game changing element in future space architectures, with the potential to increase scale and reduce cost. However, before any decisions can be made on the inclusion of resources in exploration roadmaps or future scenarios some big questions need to be answered about the viability of different resource deposits and the processes for extraction and utilisation. The missions and measurements that will be required to answer these questions, and which are being prepared by agencies and others, can only be performed through the engagement and support of the science community. In answering questions about resources, data and knowledge will be generated that is of fundamental scientific importance. In supporting resource prospecting missions the science community will de facto generate new scientific knowledge. Science enables exploration and exploration enables science.

  2. 广州地区5~15岁健康儿童高渗盐水诱导痰细胞学检查及其分类正常参考值的初步建立%Preliminary establishment of cytological examination and the normal reference values for hypertonic saline solution-induced sputum of healthy children in Guangzhou

    Institute of Scientific and Technical Information of China (English)

    陈德晖; 赖克方; 钟南山; 钟帼钰; 罗炜; 陈桥丽; 陈如冲; 林育能; 潘小安; 李瑾瑛; 吴上志

    2012-01-01

    Objective To establish the method of cytological examination and the normal reference values for hypertonic saline solution-induced sputum of healthy children (age range from 5 to 15 years ) with physical examination in Guangzhou.Method A total of 352 children,5 to 15 years old,were enrolled from primary school and middle school in Guangzhou from January to December,2010.All subjects completed a standardized questionnaire on the presence of respiratory,allergic symptoms and family history,the medical history and the physical examination was performed by doctors,lung function (forced expiratory volume at 1 s in predicted normal,FEV1 % ) was determined.There were 266 healthy children (137 males,129 females) who were selected and undergone hypertonic saline solution induction of sputum,and cytological examination was performed. Hypertonic saline ( 5% ) was nebulized and inhaled for 15 - 30 min. No expectoration within 30 min was defined as failure,and the procedure was terminated.The part of opaque and higher density sputum samples was detected by cytology.The proportion of neutrophils,lymphocytes,eosinophils,macrophages and monocytes was calculated.This study was approved by the institutional Ethics Review Committee of First Affiliated Hospital of Guangzhou Medical College.Informed consent was obtained from the legal guardians of all participants following a detailed description of the purpose and potential benefits of the study.Result There were 175 subjects' induced sputum specimens ( 175/266,65.8% ),non-qualified sputum samples were obtained from 16 of the subjects.The proportions of median (IQR) of lymphocytes were 0.012(0.020),95% CI were ranged from 0.015 to 0.022 ;neutrophils 0.207 (0.330),95% CI 0.266 -0.356 macrophages 0.761 (0.327 ),95 % CI 0.607 -0.699; eosinophils 0.004 (0.019),95% CI 0.013 -0.022.There were no significant differences in proportions of cytological findings of female or male,different age groups and second-hand smoking or not

  3. An organized, comprehensive, and security-enabled strategic response to the Haiti earthquake: a description of pre-deployment readiness preparation and preliminary experience from an academic anesthesiology department with no preexisting international disaster response program.

    Science.gov (United States)

    McCunn, Maureen; Ashburn, Michael A; Floyd, Thomas F; Schwab, C William; Harrington, Paul; Hanson, C William; Sarani, Babak; Mehta, Samir; Speck, Rebecca M; Fleisher, Lee A

    2010-12-01

    Society of Anesthesiology Committee on Trauma and Emergency Preparedness, published articles, and in-country contacts were used to guide the preparatory process. An organized strategic response to medical needs after an international natural disaster emergency can be accomplished safely and effectively within 6 to 12 days by an academic anesthesiology department, with medical system support, in a center with no previously established response system. The value and timeliness of this response will be determined with further study. Institutions with limited experience in putting an emergency medical team into the field may be able to quickly do so when such efforts are executed in a systematic manner in coordination with a health care organization that already has support infrastructure at the site of the disaster.

  4. Practice and Experience of the Establishment of Long Term Mechanism of Continuous Quality Improvement%建立医疗质量持续改进长效机制的实践与体会

    Institute of Scientific and Technical Information of China (English)

    谭天林; 欧兵玺; 廖世川; 罗力; 李雪

    2011-01-01

    探讨建立医疗质量持续改进长效机制,确保患者医疗安全,提高患者满意度.坚持将健全组织、完善制度、优化流程、全员培训、全面监控、加强沟通、整改到位等措施,贯穿于基础质量控制、环节质量控制和终末质量控3个环节,是建立医疗质量持续改进长效机制的有效方法.%The establishment of long-term mechanism for continuous improvement of health care quality is explored to ensure the safety of patients, and to improve patient satisfaction. Adhering to a sound organization, improving the system, streamlining business process, training all staff, and enhancing comprehensive monitoring and communication are needed in place corrective measures, such as quality control throughout the base, part of quality control and quality control of the three terminal links, and are effective ways of continuous quality improvement of establishing long-term mechanism.

  5. UVISS preliminary visibility analysis

    DEFF Research Database (Denmark)

    Betto, Maurizio

    1998-01-01

    The goal of this work is to obtain a preliminary assessment of the sky visibility for anastronomical telescope located on the express pallet of the International SpaceStation (ISS)} taking into account the major constraints imposed on the instrument by the ISSattitude and structure. Part of the w......The goal of this work is to obtain a preliminary assessment of the sky visibility for anastronomical telescope located on the express pallet of the International SpaceStation (ISS)} taking into account the major constraints imposed on the instrument by the ISSattitude and structure. Part...

  6. Establishment of Follow-up Testing System for ERP Sand-table Simulating Experiments%ERP沙盘模拟实验跟踪考核系统的构建

    Institute of Scientific and Technical Information of China (English)

    孙军艳; 雷朝燕

    2012-01-01

    针对ERP沙盘模拟实验中信息跟踪困难、工作繁重低效的问题,设计并开发了一套管理系统,可对实验全过程进行跟踪考核,促进了实践教学改革,提高了教学质量.%In view of the problems of ERP sand-table simulating experiment such as difficulty in information tracking, heavy workload and poor efficiency, the paper designs and develops a management system which can ensure follow-up checks and exams for the whole process of the experiments and thus improve the teaching quality.

  7. 植物学实验考核体系的建立与实验教学改革探索%A probing into the establishment of experiment assessing system and reforming experimental teaching in Botany

    Institute of Scientific and Technical Information of China (English)

    李志敏

    2001-01-01

    本文对植物学实验课的考核办法做了介绍,讨论了新的考核制度对实验教学提出的新要求。对实验教学进行了改革:(1)摸索出了“技术实验、验证实验、探索实验”三层次课程结构的划分;(2)教学内容由“封闭式”变为“开放式”;(3)突出对学生实践能力培养,完善实验的“验证性”为“探索性”;(4)变实验教学对象的“被动性”为“主动性”;(5)实验教学“软”件的激活和“硬”件的改善。%The paper probes into the new method for botanical experimental examination, and discusses the new assessing system of how to reform the traditional experimental classes. Five aspects for reforming the class are suggested as follows: 1. Dividing the class into three stages: technical experiment, validating experiment and exploring experiment. 2. Making “close” teaching manner into “open” one. 3. Focus on training students' practice ability, and completing “validating type” of experiment into “exploring type”. 4. Changing the teaching objects from “passivity” into “go-aheadism”. 5. Activating the “soft” of experimental teaching and improving “hard” one.

  8. Simultaneous whole body 18F-fluorodeoxyglucose positron emission tomography magnetic resonance imaging for evaluation of pediatric cancer: Preliminary experience and comparison with 18F-fluorodeoxyglucose positron emission tomography computed tomogra

    Institute of Scientific and Technical Information of China (English)

    Brian S Pugmire; Alexander R Guimaraes; Ruth Lim; Alison M Friedmann; Mary Huang; David Ebb; Howard Weinstein; Onofrio A Catalano; Umar Mahmood; Ciprian Catana; Michael S Gee

    2016-01-01

    AIM: To describe our preliminary experience with simultaneous whole body 18F-fluorodeoxyglucose(18F-FDG)positron emission tomography and magnetic resonance imaging(PET-MRI) in the evaluation of pediatric oncology patients.METHODS: This prospective, observational, singlecenter study was Health Insurance Portability and Accountability Act-compliant, and institutional review board approved. To be eligible, a patient was required to:(1) have a known or suspected cancer diagnosis;(2) be under the care of a pediatric hematologist/oncologist; and(3) be scheduled for clinically indicated 18F-FDG PETCT examination at our institution. Patients underwent PET-CT followed by PET-MRI on the same day. PET-CT examinations were performed using standard department protocols. PET-MRI studies were acquired with an integrated 3 Tesla PET-MRI scanner using whole body T1 Dixon, T2 HASTE, EPI diffusion-weighted imaging(DWI) and STIR sequences. No additional radiotracer was given for the PET-MRI examination. Both PET-CT and PETMRI examinations were reviewed by consensus by two study personnel. Test performance characteristics of PETMRI, for the detection of malignant lesions, including FDG maximum standardized uptake value(SUVmax) and minimum apparent diffusion coefficient(ADCmin), were calculated on a per lesion basis using PET-CT as a reference standard.RESULTS: A total of 10 whole body PET-MRI exams were performed in 7 pediatric oncology patients. The mean patient age was 16.1 years(range 12-19 years) including 6 males and 1 female. A total of 20 malignant and 21 benign lesions were identified on PET-CT. PET-MRI SUVmax had excellent correlation with PET-CT SUVmax for both benign and malignant lesions(R = 0.93). PETMRI SUVmax > 2.5 had 100% accuracy for discriminating benign from malignant lesions using PET-computed tomography(CT) reference. Whole body DWI was also evaluated: the mean ADCmin of malignant lesions(780.2 + 326.6) was significantly

  9. Establishment for quality control of experimental animal

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Tae Hwan; Kim, Soo Kwan; Kim, Tae Kyoung

    1999-06-01

    Until now, because we have imported experimental animal from foreign experimental animal corporation, we could have saved money by establishing the quality control of animal in barrier system. In order to improve the quality of animal experiment and efficiency of biomedical study, it is indispensable to control many factors that effect in the experiment. Therefore, it is essential to organize the system of laboratory animal care for enhancing reliability and revivability of experimental results. The purpose of the present investigation was to establish the quality control system of experimental animals that we can provide good quality animals according to the experimental condition of each investigator although the exact quality control system to estimate the infection of bacteria and virus easily remains ill-defined yet. Accordingly, we established the useful quality control system for microbiologic monitoring and environmental monitoring to protect experimental animal from harmful bacteria and virus.

  10. UVISS preliminary visibility analysis

    DEFF Research Database (Denmark)

    Betto, Maurizio

    1998-01-01

    The goal of this work is to obtain a preliminary assessment of the sky visibility for anastronomical telescope located on the express pallet of the International SpaceStation (ISS)} taking into account the major constraints imposed on the instrument by the ISSattitude and structure. Part...

  11. 设立护理组长在护士层级管理中的实践与体会%Practice and experience of the establishment of nurse team leaders in the hierarchical management

    Institute of Scientific and Technical Information of China (English)

    黄师菊; 周雪玲; 李晓玲; 陈妙霞

    2010-01-01

    目的 探讨设立护理组长在临床护士层级管理工作中的实践.方法 对外科病房8个病区试行设立护理组长工作岗位,实行护士长-护理组长-责任护士-助理护士层级管理模式,由护理组长或替班组长实现二级护理质控网,将护理质控前移,确保护理工作质量.结果 实行护理组长后护理服务满意度97.3%,比实施前明显提高.结论 护士层级管理体现以患者为中心的管理理念,充分发挥各层级护理人员的作用,有利于合理安排使用人力资源,更好实施层级管理,有利于护理人才的培养,推动护理专业发展.%Objective To explore the feasibility of the establishment of nurse team leaders in the hierarchical management. Methods Eight nurses were assigned as nurse team leaders in eight surgeon wards. To ensure the quality of nursing, we established the hierarchical management mode of Head nurse-nurse team leader -primary nurse, made the nurse team leader or monitor take charge of the secondary nursing quality control networks, and brought the nurse quality control work forward. Results The patient' s satisfaction to nursing service increased significantly after nurse team leader system. Conclusions The hierarchical management reflects a patient-centered philosophy, makes full use of nursing staff at all levels, and it is beneficial to arrangt human resource and talent cultivation, it can make the implementation of the hierarchical management better and promote the nursing professional development.

  12. 落实优质护理服务建立良好的护患关系的体会%The Experience of Establishing a Good nurse Patient Relationship in the Implementation of Quality care Service

    Institute of Scientific and Technical Information of China (English)

    任丽萍; 张晖

    2016-01-01

    Nursing service is an important aspect of clinical services, the quality of care will directly affect the patient’s treatment and nurse patient relationship, therefore, the implementation of quality care services in clinical practice is essential. This paper introduced the way through the rich affinity of language communication, to the patient’s point of view of empathy, improve nursing technology, carry out psychological nursing care of family and improve health education implementation of high quality nursing service, to establish a good nurse patient relationship.%护理服务是临床服务中的重要方面,护理质量的好坏直接会对患者的治疗以及护患关系造成影响,因此,在临床中落实优质护理服务至关重要。本文介绍了通过富有亲和力的语言交流,以患者角度进行换位思考,提高护理技术,开展亲情化的心理护理以及完善健康教育等方式落实优质护理服务,以建立良好的护患关系。

  13. Preliminary hazards analysis -- vitrification process

    Energy Technology Data Exchange (ETDEWEB)

    Coordes, D.; Ruggieri, M.; Russell, J.; TenBrook, W.; Yimbo, P. [Science Applications International Corp., Pleasanton, CA (United States)

    1994-06-01

    This paper presents a Preliminary Hazards Analysis (PHA) for mixed waste vitrification by joule heating. The purpose of performing a PHA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PHA is then followed by a Preliminary Safety Analysis Report (PSAR) performed during Title 1 and 2 design. The PSAR then leads to performance of the Final Safety Analysis Report performed during the facility`s construction and testing. It should be completed before routine operation of the facility commences. This PHA addresses the first four chapters of the safety analysis process, in accordance with the requirements of DOE Safety Guidelines in SG 830.110. The hazards associated with vitrification processes are evaluated using standard safety analysis methods which include: identification of credible potential hazardous energy sources; identification of preventative features of the facility or system; identification of mitigative features; and analyses of credible hazards. Maximal facility inventories of radioactive and hazardous materials are postulated to evaluate worst case accident consequences. These inventories were based on DOE-STD-1027-92 guidance and the surrogate waste streams defined by Mayberry, et al. Radiological assessments indicate that a facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous materials assessment indicates that a Mixed Waste Vitrification facility will be a Low Hazard facility having minimal impacts to offsite personnel and the environment.

  14. Drug Establishments Current Registration Site

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Drug Establishments Current Registration Site (DECRS) is a database of current information submitted by drug firms to register establishments (facilities) which...

  15. Preliminary criteria for shallow-land storage/disposal of low-level radioactive solid waste in an arid environment

    Energy Technology Data Exchange (ETDEWEB)

    Shord, A. L.

    1979-09-01

    Preliminary criteria for shallow land storage/disposal of low level radioactive solid waste in an arid environment were developed. Criteria which address the establishment and operation of a storage/disposal facility for low-level radioactive solid wastes are discussed. These were developed from the following sources: (1) a literature review of solid waste burial; (2) a review of the regulations, standards, and codes pertinent to the burial of radioactive wastes; (3) on site experience; and (4) evaluation of existing burial grounds and practices. (DMC)

  16. The C.E.B.A. Mini Module on the STS-107 Mission: Data of Ground Experiments and Preliminary Results of the third Spaceflight of an Artificial Aquatic Ecosystem

    Science.gov (United States)

    Bluem, V.; Paris, F.; Bungart, S.

    The C.E.B.A.S MINI MODULE is the miniaturized version of an artificial aquatic ecosystem consisting of four subcomponents: a ZOOLOGICAL COMPONENT (aquarium for animals), a BOTANICAL COMPONENT (higher water plant bioreactor), a MICROBIAL COMPONENT (bacteria filter) and an ELECTRONICAL COMPONENT (data acquisition, control unit). It has a total volume of 8.6 liters and contains the ovoviviparous teleost Xiphophorus helleri (swordtail), larvae of the ovuliparous cichlid fish Oreochromis mossambicus, the pulmonate water snail Biomphalaria glabrata, the rootless (non-graivitropic) higher water plant Ceratophyllum demersum (hornweed) and special strains of ammonia oxidizing bacteria. This device was already flown twice successfully in space with the space shuttle missions STS- 89 and STS-90 (NEUROLAB) in 1998. It will fly a third time with the STS-107-mission the launch of which has been repeatedly shifted December 222, April 2001, October 2001) and is now finally scheduled for June 2002. The main focus of scientific interest in the past missions were system performance, reproductive biology (reproductive function of adult females including endocrine system, fertilization, gonadal development in juveniles), vestibular and immunological research in X. helleri, embryology and shell formation in B. glabrata, general morphology and physiology of C. demersum and groth rates of the bacteria. The standard load of the system were 4 adult and 200 neonate X. helleri, 30 adult B. glabrata and 30 g of C. demersum. The evaluation of these experiments showed that all reproductive functions and the immune system of the fishes snails remained undisturbed in space, that the snails developed normally and exhibited no disturbance of shell formation and that the plants showed growth and photosynthesis rates comparable to those on Earth. So, as a logical continuation, the main topics for the STS-107 mission are the remaining important questions in X. helleri biology: puberty, male sexual

  17. Establishment of persistent foot-and-mouth disease virus (FMDV) infection in MDBK cells.

    Science.gov (United States)

    Kopliku, Lela; Relmy, Anthony; Romey, Aurore; Gorna, Kamila; Zientara, Stephan; Bakkali-Kassimi, Labib; Blaise-Boisseau, Sandra

    2015-10-01

    In addition to acute infection and disease, foot-and-mouth disease virus (FMDV) can cause persistent infection in ruminants. Such "carrier" animals represent a potential risk for FMDV transmission to susceptible animals. However, the mechanisms and the factors that determine FMDV persistence remain unknown. We describe here the establishment of FMDV type O persistent infection in a bovine epithelial cell line (Madin-Darby bovine kidney; MDBK). Preliminary experiments to assess the permissivity of MDBK cells to FMDV O infection revealed an unusual pattern of infection: after the initial phase of acute cell lysis, new monolayers formed within 48-72 h post-infection. We found that some cells survived cytolytic infection and subsequently regrew, thereby demonstrating that this bovine cell line can be persistently infected with FMDV type O. Further evidence that MDBK cells were persistently infected with FMDV includes: (i) detection of viral RNA in cells as well as in cell culture supernatants, (ii) detection of viral antigens in the cells by immunofluorescence analysis, and (iii) production of infectious viral particles for up to 36 cell passages. Furthermore, preliminary sequence analysis of persistent virus revealed a single nucleotide substitution within the VP1 coding region, resulting in the V50A amino acid substitution. This bovine model of FMDV persistence holds promise for the investigation of the viral and cellular molecular determinants that promote FMDV persistence.

  18. Preliminary Results on Sediment Sorting Under Intense Bedload Transport

    Science.gov (United States)

    Hernandez Moreira, R. R.; Vautin, D.; Mathews, S. L.; Kuprenas, R.; Viparelli, E.

    2014-12-01

    Previous experiments show that parallel-laminated deposits are emplaced under upper plane bed regime by the migration of small-amplitude, long-wavelength bedforms. The present research focuses on how sediment is sorted under upper plane bed and sheet flow transport regimes, and whether parallel-lamination is inhibited during sheet flow transport. The problem of studying the sorting of sediment under so intense transport conditions is plagued by the uncertainties related to flow resistances and bedload transport rates. We simplify the problem by first running the experiments with uniform sediment, to establish a baseline that will aid in the design of the experiments with poorly sorted material. We are running experiments at the Hydraulics Laboratory of the Department of Civil and Environmental Engineering at the University of South Carolina in Columbia, in a unidirectional sediment-feed flume, 9 meters long by 0.2 meters wide, of which 7 meters are used as test section. During the experiments, water surface and bed elevations are periodically measured to characterize the global parameters of the flow, e.g. mean flow velocity and bed shear stress. When the flow and the sediment transport reach conditions of mobile bed equilibrium, bed elevation fluctuations are measured with ultrasonic transducer systems at six fixed locations. Channel bed aggradation is then induced by slowly raising the tail gate of the flume such that there is no change in transport regime, as confirmed by additional measurements of water surface and bed elevation and bed elevation fluctuations. Preliminary observations under upper plane bed regime show the formation of the small-amplitude and long-wavelength bedforms, as well as hints of parallel lamination in the deposits. In the near future we aim to achieve sheet flow transport conditions with both uniform and non-uniform grain size distributions to look at the internal structure of the emplaced deposit.

  19. Establishing Ergonomics in Industrially Developing Countries

    Energy Technology Data Exchange (ETDEWEB)

    Stewart, K; Silverstein, B; Kiefer, M

    2005-08-29

    The introduction of ergonomics is an ongoing effort in industrially developing countries and will ultimately require an organized, programmatic approach spanning several countries and organizations. Our preliminary efforts with our partner countries of Viet Nam, Thailand, and Nicaragua have demonstrated that a one-time course is just the first step in a series of necessary events to provide skills and create an infrastructure that will have lasting impact for the host country. To facilitate that any sort of training has a lasting impact, it is recommended that host countries establish a 'contract' with class participants and the guest instructors for at least one follow-up visit so instructors can see the progress and support the participants in current and future efforts. With repeated exchanges, the class participants can become the 'in country experts' and the next generation of ergonomic trainers. Additionally, providing participants with an easy to use hazard assessment tool and methods for evaluating the financial impact of the project (cost/benefit analysis) will assist increase the likelihood of success and establish a foundation for future projects. In the future, developing trade and regionally/culturally specific 'ergonomics toolkits' can help promote broader implementation, especially where training resources may be limited.

  20. “5+3”一体化背景下强化临床医学八年制学生临床能力培养的初步思考%Preliminary ideas of strengthening the clinical competence of “eight-year program” medical students under the background of establishment of integrated "5+3" medical education system in China

    Institute of Scientific and Technical Information of China (English)

    闫剑群; 王渊; 程彦斌

    2015-01-01

    "Cooperation of Clinical Practice and Medical Education" is a system guarantee for effectively linking undergraduate, postgraduate and continuing medical education, optimizing educational program, academic degree system and clinical talents training standardization, and strengthening and improving the relevant support mechanism. Under such a background, it is a challenge to advance the clinical competence of "eight-year program" medical students and complete the standardized resident training. In this article, these issues are discussed and preliminary suggestions are presented, based on the education reform for eight-year program medical students at Xi'an Jiaotong University.%“医教协同”是促进我国医学教育链环中院校教育、毕业后教育和继续教育有效衔接,优化医学教育学制学位体系建设和临床医学人才标准化、规范化培养制度建设,加强和完善相应的支撑、保障体系的制度保证。在这一背景下,如何提高临床医学专业八年制学生的临床能力并完成规范化培训,是一个值得认真思考的问题。本文以西安交通大学八年制临床医学专业的培养体系为例进行讨论并提出了初步建议,以期与同行共同探讨。

  1. On Preliminary Breakdown

    Science.gov (United States)

    Beasley, W. H.; Petersen, D.

    2013-12-01

    The preliminary breakdown phase of a negative cloud-to-ground lightning flash was observed in detail. Observations were made with a Photron SA1.1 high-speed video camera operating at 9,000 frames per second, fast optical sensors, a flat-plate electric field antenna covering the SLF to MF band, and VHF and UHF radio receivers with bandwidths of 20 MHz. Bright stepwise extensions of a negative leader were observed at an altitude of 8 km during the first few milliseconds of the flash, and were coincident with bipolar electric field pulses called 'characteristic pulses'. The 2-D step lengths of the preliminary processes were in excess of 100 meters, with some 2-D step lengths in excess of 200 meters. Smaller and shorter unipolar electric field pulses were superposed onto the bipolar electric field pulses, and were coincident with VHF and UHF radio pulses. After a few milliseconds, the emerging negative stepped leader system showed a marked decrease in luminosity, step length, and propagation velocity. Details of these events will be discussed, including the possibility that the preliminary breakdown phase consists not of a single developing lightning leader system, but of multiple smaller lightning leader systems that eventually join together into a single system.

  2. Experiences in certification of packages for transportation of fresh nuclear fuel in the context of new safety requirements established by IAEA regulations (IAEA-96 regulations, ST-1) for air transportation of nuclear materials (requirements to C-type packages)

    Energy Technology Data Exchange (ETDEWEB)

    Dudai, V.I.; Kovtun, A.D.; Matveev, V.Z.; Morenko, A.I.; Nilulin, V.M.; Shapovalov, V.I.; Yakushev, V.A.; Bobrovsky, V.S.; Rozhkov, V.V.; Agapov, A.M.; Kolesnikov, A.S. [Russian Federal Nuclear Centre - All-Russian Research Inst. of Experimental Physics, Sarov (Russian Federation)]|[JSC ' ' MSZ' ' , Electrostal (Russian Federation)]|[JSC ' ' NPCC' ' , Novosibirsk (Russian Federation)]|[Minatom of Russia, Moscow (Russian Federation)]|[Gosatomnadzor of Russia, Moscow (Russian Federation)

    2004-07-01

    Every year in Russia, a large amount of domestic and international transportation of fresh nuclear fuel (FNF) used in Russian and foreign energy and research atomic reactors and referred to fissile materials based on IAEA Regulations is performed. Here, bulk transportation is performed by air, and it concerns international transportation in particular. According to national ''Main Regulations for Safe Transport and physical Protection of Nuclear Materials (OPBZ- 83)'' and ''Regulations for the Safe Transport of Radioactive Materials'' of the International Atomic Energy Agency (IAEA Regulations), nuclear and radiation security under normal (accident free) and accident conditions of transport must be completely provided by the package design. In this context, high requirements to fissile packages exposed to heat and mechanical loads in transport accidents are imposed. A long-standing experience in accident free transportation of FM has shown that such approach to provide nuclear and radiation security pays for itself completely. Nevertheless, once in 10 years the International Atomic Energy Agency on every revision of the ''Regulations for the Safe Transport of Radioactive Materials'' places more stringent requirements upon the FM and transportation thereof, resulting from the objectively increasing risk associated with constant rise in volume and density of transportation, and also strained social and economical situation in a number of regions in the world. In the new edition of the IAEA Regulations (ST-1), published in 1996 and brought into force in 2001 (IAEA-96 Regulations), the requirements to FM packages conveyed by aircraft were radically changed. These requirements are completely presented in new Russian ''Regulations for the Safe Transport of Radioactive Materials'' (PBTRM- 2004) which will be brought into force in the time ahead.

  3. 部分免疫耐受诱导方案在小肠移植中的应用%Preliminary experience with partial tolerance protocol in small bowel transplantation

    Institute of Scientific and Technical Information of China (English)

    李元新; 李宁; 李幼生; 倪小冬; 李民; 吴波; 王剑; 黎介寿

    2009-01-01

    目的 报道4例小肠移植患者应用部分免疫耐受方案的初步经验.方法 小肠移植术中给予CD52单克隆抗体(Campath 1H)30 mg及甲泼尼龙2 g.术后单用低剂量普乐可复维持,不使用激素.术后前3个月普乐可复血药浓度维持在10-15μg/L,术后第4个月开始,普乐可复血药浓度减低至5-10μg/L,术后第7个月,减低至5 μg/L左右.结果 4例患者中2例生存期已超过1年;另2例患者中1例术后6个月,1例术后2个月余,均在顺利康复中.在术后0~3个月2例患者发生移植肠黏膜活检病理学诊断不确定(IND级)至轻度(1级)排斥反应3次,术后3~6个月2例患者发生IND级至1级排斥反应共3次,术后7~12个月1例患者发生中度(2级)排斥反应1次.排斥反应经治疗均成功缓解.移植肠功能良好,分别于术后2~3周彻底摆脱静脉营养,依赖口服饮食维持营养状态.结论 小肠移植术后应用Campath 1H诱导,单用低剂量普乐可复、无激素维持的部分免疫抑制方案,能有效地控制排斥反应.患者移植肠功能良好,能尽早摆脱静脉营养.%Objective To report the preliminary experience of 4 cases of small bowel transplantation. Methods Thirty microgram of Campath 1H was infused during the small bowel transplantation. The patients received 1 gram of Solu-Medrol followed by the Campath 1 H and another gram of Solu-Medrol before reperfusion. The infusion of tacrolimus started iust after reperfusion. The route of tacrolimus administration was transferred from vein to gut tract gradually. the tacrolimus trouth levels were aimed at 10-15μg/L within the first 3 postoperative months, 5-10μg/L at 4-6 months post-operation and taped to 5 μg/L thereafter. Results Two of these 4 cases survived more than one year. The follow-ups of other 2 patients were 6 and 2 months respectively. Three episodes of IND to mild acute rejection verifted by pathology through routine ileoscopical biopsy were found at 1-3 months post

  4. Experiencia preliminar en el tratamiento combinado de metástasis vertebrales mediante radiofrecuencia y cifoplastia en sesión única Preliminary experience in the treatment of vertebral metastases by radiofrequency and Kyphoplasty combined in one single session

    Directory of Open Access Journals (Sweden)

    G. Buitrago

    2013-02-01

    de radiofrecuencia asociada a cifoplastia en la enfermedad metastásica vertebral puede contribuir al manejo del dolor refractario al tratamiento médico y al control local de la enfermedad.Objectives: Describe our preliminary experience in the treatment of vertebral metastases by radiofrequency and Kyphoplasty combined in one single session. Material and methods: Four patients with histologically confirmed single spinal metastasis (breast, prostate, lung and myeloma in L1, L5, D12, D12, respectively were treated. The indication in all cases was pain with a poor response to medical treatment. All patients had pain in the range 6-7 visual analogue scale (VAS. In two cases there was a lytic lesion of the spinal posterior wall. After obtaining informed consent, and under sedation and local anesthetic the procedure took place. The transpedicular approach took place with a 11 G bone puncture system. Two radiofrequency needles were coaxially inserted to carry out an ablation cycle through each pedicle. During the ablation cycle the tip of the ablation neddle stood between the anterior and middle third of the vertebral body, while the second needle was used as thermal sensor with its end to the height of the vertebral posterior wall. The duration of each cycle of ablation was 8 minutes reaching intratumoral temperatures of 70-80 ºC. Transpedicular Kyphoplasty was performed subsequently. Results: No complications were reported during or after the procedure and patients were discharged in the first 24 hours. There was an immediate improvement in pain after the procedure (with a VAS 1-2 intensity pain in all patients. During follow up, analgesic medication was withdrawn in three patients, and there was no evidence of disease progression or recurrence of pain (pain intensity 1 (VAS in a follow-up in the range of 8-14 months. Clinical and radiological follow-up after discharge could not be performed on a patient. Conclusion: The use of radio-frequency associated with

  5. Three-dimensional rotational angiography of the carotid arteries with high-flow injection from the aortic arch. Preliminary experience; Angiografia rotazionale tridimensionale delle carotidi mediante iniezione ad alto flusso dell'arco aortico. Esperienza preliminare

    Energy Technology Data Exchange (ETDEWEB)

    Pozzi Mucelli, Fabio; Calgaro, Antonio; Bruni, Stefano; Bottaro, Lorella; Pozzi Mucelli, Roberto [Trieste Univ., Trieste (Italy). Unita' Clinico Operativa di Radiologia

    2005-02-01

    Purpose: Three-dimensional rotational angiography (3DRA) is a new technique based on a rotational angiographic acquisition able to display arterial vessels in a 3D rendering mode. The system was mainly developed for neuroradiological evaluations but preliminary extracranial experiences have also been reported. The aim of our work was to compare the results of three-dimensional angiography of the carotid arteries done with high-flow injection of contrast medium from the aortic arch with the results of selective angiography. Materials and methods: Twenty patients underwent digital angiography of the supra-aortic vessels in order to quantify a stenosis of the carotid bifurcations previously detected at Doppler Ultrasound. Examinations were performed with the Philips Integris Allura system provided with the rotational angiography (RA) tool connected to a workstation for three-dimensional reconstruction able to display vessels in a 3D fashion (Volume Rendering, Shaded Surface Display), automatically remove bone structures (cervical spine, calcified plaque, etc) and perform an automatic analysis of the vessel diameter and surface area at the point of major stenosis and in the disease-free vessel segments above and below. The carotid evaluation was done either with selective catheterization and the two standard AP and LL projections and with RA after contrast medium injection from the aortic arch followed by 3D reconstruction. Results: The comparison of the selective angiography and three-dimensional images was possible in 37 out of 40 carotid bifurcations (3 internal carotid arteries were occluded) and a good diagnostic quality was obtained in 35 out of 37 cases with an high correlation in the degree of stenosis. In 2/37 cases with calcified plaques the degree of stenosis was effectively demonstrated only after electronic subtraction of the calcified component of the plaque. Conclusions: The technique we propose proved to be feasible in all cases with a good correlation

  6. Collaborative experience

    DEFF Research Database (Denmark)

    Mortensen, Thomas Bøtker

    sample of firms, an establish way of measuring the outcome of product development and a new way of measuring experience. Where the previous research in this field primarily uses secondary databases, this research project collects primary data by an online questionnaire to the NPD manager from one......, that the largest effects from collaborative experience is from recent collaborative experience, since knowledge depreciates when it is not used. Methodologically contribution: The research project studies the dyad and aims at introducing, to this field of research, an established way of collecting data, a new...... of the new product development as a performance measure. Finally, where previous research primarily has used the number of collaborations as a measure of collaborative experience, this research includes the recency in the measure of collaborative experience. Results: Since data has not yet been collected...

  7. Vertical infraclavicular brachial plexus block in children: a preliminary study.

    NARCIS (Netherlands)

    Jose Maria, B. de; Tielens, L.K.P.

    2004-01-01

    BACKGROUND: Brachial plexus blockade is a well-established technique in upper limb surgery. Among the infraclavicular approaches, the vertical infraclavicular brachial plexus (VIP) block is easy to perform and has a large spectrum of nerve blockade. The aim of this preliminary study was to determine

  8. Establishment and preliminary analysis of biomechanical behavior of lumbar dynamic stability system according to the three-dimensional finite element method%基于三维有限元法的腰椎动态稳定系统建立及生物力学行为初步分析

    Institute of Scientific and Technical Information of China (English)

    陈为坚; 段扬; 林周胜; 李贵涛; 孙鸿涛; 刘燕芳

    2015-01-01

    目的:基于三维有限元建模方法,建立腰椎弓根动态稳定钉棒系统的模型,初步分析处于不同载荷下腰椎的应力分布及各节段的活动度。方法对一名健康成年男性志愿者行CT扫描,用Mimics 10.01、Abaqus 6.10软件建立正常人L3~S2节段模型。结合Bioflex动态稳定系统建立模型。对模型施加150 N预载荷,在3个主平面施加10 Nm扭矩,获得前屈、后伸、侧屈及旋转6种运动状态下的Bioflex钉棒应力分布和各节段的椎间活动度,初步测定后伸及旋转运动的活动度。结果建立的腰椎L3~S2节段和动态稳定系统有限元模型符合生物力学模型,初步分析显示腰椎动态稳定系统的应力主要集中于螺旋固定棒;在各种加载下,腰椎动态固定的节段活动度明显降低。结论基于三维有限元方法建立的Bioflex腰椎弓动态固定模型能很好地模拟腰椎的动态固定力学活动,可以对固定后的腰椎的应力和各种活动进行很好的模拟,具有很好的研究价值。%Objective To construct the dynamic lumbar pedicle scree system based on the three -dimensional fi-nite element model , thus to preliminarily analyze the stress distribution under different loads and the range of motion (ROM).Methods CT scan of the L3 ~S2 section of a healthy adult male volunteer was performed , while Mimics 10.01 and Abaqus 6.10 software were introduced to establish normal segmental model .Bioflex pedicle screw and elastic rod were used to establish dynamic stability system model .Under 150 N preload, and 10 Nm torque to three principal planes , the stress distribution in flexion , extension , lateral bending and torsion were simulated , while the ROMs of extension and tor-sion were also analyzed .Results The establishment of a lumbar L 3 ~S2 segmental finite element model and the dynamic stability system conformed to biomechanical model .Stress mainly concentrated on the elastic rods , when

  9. catering establishments of Awassa Town

    African Journals Online (AJOL)

    health sector, owners of the establishments and the community to work together and comply with the optimum ... vaious eating, drinking and hotel establishments ... Hotel and Tourism Commission (Proclamation. No 182/1980). ... parties in managing and improving of the business ... About 14,965 people were found to be.

  10. Chinese Women Lawyers Society Established

    Institute of Scientific and Technical Information of China (English)

    1994-01-01

    ON November 12, 1993, the Chinese Women Lawyers Society was established in Beijing. The more than 10,000 women lawyers in the country were excited to have their own organization. Xu Weihua, secretary-general of the society and a lawyer working in the All-China Women’s Federation, said: "The society’s establishment will promote the participation of

  11. Environmental Survey preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    1988-04-01

    This report presents the preliminary findings from the first phase of the Environmental Survey of the United States Department of Energy (DOE) Sandia National Laboratories conducted August 17 through September 4, 1987. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with Sandia National Laboratories-Albuquerque (SNLA). The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at SNLA, and interviews with site personnel. 85 refs., 49 figs., 48 tabs.

  12. Ruiz Volcano: Preliminary report

    Science.gov (United States)

    Ruiz Volcano, Colombia (4.88°N, 75.32°W). All times are local (= GMT -5 hours).An explosive eruption on November 13, 1985, melted ice and snow in the summit area, generating lahars that flowed tens of kilometers down flank river valleys, killing more than 20,000 people. This is history's fourth largest single-eruption death toll, behind only Tambora in 1815 (92,000), Krakatau in 1883 (36,000), and Mount Pelée in May 1902 (28,000). The following briefly summarizes the very preliminary and inevitably conflicting information that had been received by press time.

  13. Establishment of an oxaliplatin-resistant human colon carcinoma HCT116/L-OHP cell and preliminary,exploration for the mechanism of resistance%人结肠癌奥沙利铂耐药细胞HCT116/L-OHP的建立及其耐药机制初探

    Institute of Scientific and Technical Information of China (English)

    陆海; 孙珏; 许建华; 范忠泽

    2011-01-01

    目的:建立人结肠癌奥沙利铂(oxaliplatin,L-OHP)耐药细胞HCT116/L-OHP,并初步探讨其可能的耐药机制.方法:通过逐步增加作用于亲代细胞HCT116的L-OHP浓度与间断大剂量L-OHP作用,建立耐药细胞HCT116/L-OHP;MTT法检测L-OHP、5-氟尿嘧啶(5-fluorouracil,5-FU)、顺铂(cisplatin)和7-乙基-10-羟基喜树碱(7-ethyl-10-hydrol-camptothecin,HCPT)对HCT116和HCT116/L-OHP细胞的细胞毒性;蛋白质印迹法检测相关耐药蛋白的表达;基因芯片检测信号通路的改变.结果:成功构建了稳定耐药的耐药细胞HCT116/L-OHP,耐药倍数为17倍,与5-FU、DDP和HCPT有不同程度的交叉耐药性.与HCT116细胞比较,HCT116/L-OHP细胞中P糖蛋白(P-glycoprotein,P-gp)、肺耐药蛋白(lung resistance protein,LRP)和谷胱甘肽S转移酶(glutathioneS-transferase,GST)的表达上调(P<0.01),9条信号通路上调(P<0.05),其中细胞周期信号通路上调最明显,p53信号通路次之.结论:HCT116/L-OHP细胞具有稳定的耐药性,其耐药机制可能与细胞耐药蛋白表达、细胞周期和p53信号通路表达上调有关.%Objective: To establish an oxaliplatin (L-OHP)-resistant human colon carcinoma HCT116/L-OHP cell, and to preliminarily explore the mechanism of resistance. Methods: Oxaliplatin-resistant HCT116/L-OHP cells were established by gradually increasing the concentration of L-OHP and intermittent treatment with high-dose concentration on parental cells (HCT116). The cytotoxicities in HCT116 and HCT116/L-OHP cells induced by L-OHP, 5-fluorouracil (5-FU), cisplatin (DDP) and 7-ethyl-10-hydrol-camptothecin (HCPT) were detected by MTT assay. The expressions of resistance-associated proteins were determined by Western blotting. The changes of signaling pathway were measured by gene chips. Results: The HCT116/L-OHP cells with stable resistance were successfully established. The resistance fold was 17. The HCT116/L-OHP cells had cross-resistance with 5-FU, DDP and HCPT. The expression

  14. 妊娠期女性血细胞主要参数生物参考区间建立的初步探讨%Preliminary investigation on the establishment of biological reference intervals about the main parameters of blood cells among pregnant women

    Institute of Scientific and Technical Information of China (English)

    葛雅芳; 沈云岳; 唐振华

    2014-01-01

    目的:建立本实验室妊娠期女性血细胞主要参数的生物参考区间。方法选取331例正常足月分娩的孕妇,追溯其孕期检查记录,用 SAS 8.1软件对孕期间进行的2次血细胞常规检测结果进行统计分析,获得参考区间。结果比较妊娠早期和妊娠晚期的各项血常规检验结果,差异具有统计学意义(P 均<0.05)。参考区间分析显示血小板(PLT)、单核细胞百分比(M %)和嗜碱性粒细胞百分比(B %)检验结果均在现行参考区间内,故继续沿用原有参考区间;血细胞比容(HCT)和嗜酸性粒细胞百分比(E %)检验结果,经验证可合并参考区间;而红细胞计数(RBC)、血红蛋白(Hb)、白细胞计数(WBC)、中性粒细胞百分比(N %)及淋巴细胞百分比(L%)需分组建立不同的参考区间。结论新建的生物参考区间更符合孕期的生理变化,能更好的指导临床诊断和治疗。%Objective To establish the biological reference intervals about the main parameters of blood cells among pregnant women in our laboratory.Methods A total of 331 pregnant women who had normal and term delivery were enrolled.According to their medical records,their 2 reports of pregnancy routine blood cell tests were obtained. The results were analyzed statistically,and the biological reference intervals were calculated by SAS 8.1 software. Results There was statistical significance in all parameters of pregnancy routine blood cell tests between the first and third trimesters (P <0.05).The results of biological reference intervals showed that the 2 sets of data about platelet (PLT),monocyte percentage (M%)and basophilic granulocyte percentage (B %)were all within current biological reference intervals,then the current biological reference intervals could be used for pregnancy.The 2 sets of data about hematocrit (HCT)and eosinophile granulocyte percentage (E %)could be combined to

  15. 牛瑟氏泰勒虫二温式PCR快速检测技术的建立及初步应用%Establishment of two-temperature PCR for the rapid detection of Theileria sergenti and its preliminary application

    Institute of Scientific and Technical Information of China (English)

    丁晓双; 夏晓辉; 张晓轩; 海旭楠; 许应天

    2013-01-01

    为建立一种牛瑟氏泰勒虫快速检测技术,根据GenBank上已发表的牛瑟氏泰勒虫P23表面蛋白基因序列(D84447)设计1对特异性引物,扩增出大小为244 bp的基因片段,经克隆、测序分析,与已知基因序列同源性为100%.用该对引物建立的牛瑟氏泰勒虫二温式PCR能检测出的最高敏感度为171 fg/μL,与牛新孢子虫、弓形虫和卵形巴贝斯虫不产生交叉反应,对48份临床血液样本进行检测,阳性检出率为66.67%.用同一对引物对28份临床血液样本分别进行二温式PCR和三温式PCR检测,阳性符合率为95%,总符合率为96.43%.结果表明,该方法具有快速、敏感、特异等优点,可用于牛瑟氏泰勒虫病的快速临床诊断及流行病学调查.%To establish a rapid method to detect Theileria sergenti,a pair of primers was designed according to the gene encoding P23 major surface protein of T.sergenti(D84447).The 244 bp gene fragment was amplified,and the sequencing analysis showed 100% of homology with known gene sequence.The two-temperature PCR was established and its highest susceptibility was 171 fg/μL.The method showed no cross reaction with bovine Neospora caninum,Toxoplasma gondii and Babesia ovata.In 48 tested clinical blood samples,the positive rate was 66.67%.When 28 clinical blood samples were detected using the same pair of primers by two-temperature and three-temperature PCR,respectively,the positive coincidence rate was 95%,and the whole coincidence rate was 96.43%.The results indicated that the two-temperature PCR could be used in the rapid clinical diagnosis and epidemiological investigation in T.sergenti infection.

  16. Preliminary safety analysis methodology for the SMART

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Kyoo Hwan; Chung, Y. J.; Kim, H. C.; Sim, S. K.; Lee, W. J.; Chung, B. D.; Song, J. H. [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2000-03-01

    This technical report was prepared for a preliminary safety analysis methodology of the 330MWt SMART (System-integrated Modular Advanced ReacTor) which has been developed by Korea Atomic Energy Research Institute (KAERI) and funded by the Ministry of Science and Technology (MOST) since July 1996. This preliminary safety analysis methodology has been used to identify an envelope for the safety of the SMART conceptual design. As the SMART design evolves, further validated final safety analysis methodology will be developed. Current licensing safety analysis methodology of the Westinghouse and KSNPP PWRs operating and under development in Korea as well as the Russian licensing safety analysis methodology for the integral reactors have been reviewed and compared to develop the preliminary SMART safety analysis methodology. SMART design characteristics and safety systems have been reviewed against licensing practices of the PWRs operating or KNGR (Korean Next Generation Reactor) under construction in Korea. Detailed safety analysis methodology has been developed for the potential SMART limiting events of main steam line break, main feedwater pipe break, loss of reactor coolant flow, CEA withdrawal, primary to secondary pipe break and the small break loss of coolant accident. SMART preliminary safety analysis methodology will be further developed and validated in parallel with the safety analysis codes as the SMART design further evolves. Validated safety analysis methodology will be submitted to MOST as a Topical Report for a review of the SMART licensing safety analysis methodology. Thus, it is recommended for the nuclear regulatory authority to establish regulatory guides and criteria for the integral reactor. 22 refs., 18 figs., 16 tabs. (Author)

  17. Repository Subsurface Preliminary Fire Hazard Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Richard C. Logan

    2001-07-30

    This fire hazard analysis identifies preliminary design and operations features, fire, and explosion hazards, and provides a reasonable basis to establish the design requirements of fire protection systems during development and emplacement phases of the subsurface repository. This document follows the Technical Work Plan (TWP) (CRWMS M&O 2001c) which was prepared in accordance with AP-2.21Q, ''Quality Determinations and Planning for Scientific, Engineering, and Regulatory Compliance Activities''; Attachment 4 of AP-ESH-008, ''Hazards Analysis System''; and AP-3.11Q, ''Technical Reports''. The objective of this report is to establish the requirements that provide for facility nuclear safety and a proper level of personnel safety and property protection from the effects of fire and the adverse effects of fire-extinguishing agents.

  18. Survey of CELSS Concepts and Preliminary Research in Japan

    Science.gov (United States)

    Ohya, H.; Oshima, T.; Nitta, K.

    1985-01-01

    Agricultural and other experiments relating to the development of a controlled ecological life support system (CELSS) were proposed. The engineering feasibility of each proposal was investigated by a CELSS experiment concept met study group. The CELSS experiment concept to clarify the goals of CELSS and to determine three phases to achieve the goals. The resulting phases, or missions, and preliminary proposals and studies needed to develop a CELSS are described.

  19. 40-slice coronary CTA: initial experience and establishing a practice

    Energy Technology Data Exchange (ETDEWEB)

    Green, C. [Dept. of Radiology, Fletcher Allen Health Care and the Univ. of Vermont Coll. of Medicine, Burlington, VT (United States); Watkins, M. [Dept. of Cardiology, Fletcher Allen Health Care and the Univ. of Vermont Coll. of Medicine, Burlington, VT (United States)

    2005-07-01

    The introduction of 4-slice scanners with subsecond gantry rotation times paved way for such demanding applications as cardiac imaging. However, challenges remained. For example, the breath hold times of 40 seconds caused many patient groups to be excluded. Some of these issues were addressed by the introduction of 16-slice CT scanners with submillimeter spatial resolution and faster gantry rotation times, resulting in a significant decrease in the coverage time (less than 20 s). Further developments in scanner technology were brought about by the introduction of 40- and 64-slice scanners, such as the Philips' Brilliance, with a z-axis coverage of 40 mm, making it possible to cover the entire cardiac anatomy in less than 15 seconds [1]. Additionally, the COBRA trademark adaptive multi-cycle reconstruction approach can result in further improvement in temporal resolution by using projection data from two or more cardiac cycles [2-5]. (orig.)

  20. 牛副流感病毒3型抗体间接 ELISA 检测方法的建立与初步应用%Establishment and Preliminary Application of an Indirect ELISA for Detecting Antibodies against Bovine Parainfluenza Virus Type 3

    Institute of Scientific and Technical Information of China (English)

    杨建乐; 赵贵民; 侯佩莉; 王洪梅; 李杰; 何洪彬

    2016-01-01

    In order to establish an indirect ELISA (iELISA)for detecting antibodies against bovine parain-fluenza virus type 3 (BPIV3),the truncated NP-HN gene was cloned and pET28a(+)-NP-HN vector of prokaryotic expression was constructed.We optimized the ELISA reaction conditions using the NP-HN re-combinant protein as coating antigen,and established an iELISA method to specifically detect the positive serum of BPIV3.Further the iELISA method was compared with virus neutralization test and imported ELISA kits,respectively.Finally,270 clinical serum samples were tested.The results showed that the re-combinant 44 ku protein could highly expressed in the form of soluble and inclusion bodies in E.coli,which had good antigenic specificity and reactionogenicity,and had no cross reaction with positive serum of bovine viral diarrhea virus,infectious bovine rhinotracheitis virus and other respiratory pathogens.The coefficients of variation for intra and inter-assay were lower than 8%.The total coincidence rate with virus neutraliza-tion test and imported ELISA kit were 96.67% and 98.89%.The total positive rate of 270 clinical serum samples from Shandong,Liaoning,and Tianjin was 82.59% (223/270).These results demonstrated that BPIV3 indirect ELISA method was specific and sensitive,and can be used for epidemiological investigation and antibody detection for BPIV3.%旨在建立牛副流感病毒3型(BPIV3)抗体间接 ELISA 检测方法。克隆 NP-HN 截短串联基因并构建原核表达载体 pET28a(+)-NP-HN,诱导纯化 NP-HN 重组蛋白作为包被抗原,优化 ELISA 反应条件,建立 BPIV3抗体间接 ELISA 检测方法,进一步与病毒中和试验和进口 ELISA 试剂盒进行比较,应用本方法对270份临床血清样本进行了检测。结果表明,表达的 NP-HN 重组蛋白大小为44 ku,具有良好的反应原性,建立的 ELISA 检测方法特异性强,与牛的主要呼吸道病原如牛病毒性腹泻病毒、牛传染性鼻气

  1. Preliminary studies on establishment of indicator system to evaluate basic capacities of trainers of training for community general practitioners in Shanghai%上海市社区全科师资基本能力评估指标体系的建立

    Institute of Scientific and Technical Information of China (English)

    张渊; 杨华; 王天浩; 祝墡珠

    2011-01-01

    目的 探讨建立上海市社区全科师资基本能力的评估指标体系,以规范社区全科师资队伍的建设和管理.方法 对190名上海市12个区县从事全科临床医疗、社区卫生服务行政管理及全科医师规范化在培学员行问卷调查,了解社区全科师资应该具备的基本能力;根据问卷调查结果拟定"社区全科师资基本能力评估指标体系"评议表,选择从事全科医疗、全科教学、公共卫生事业及卫生行政管理等28位专家,进行两轮德尔菲法咨询,经数据统计分析咨询结果、意见汇总确立评估指标体系.结果 建立的社区全科师资基本能力评估指标体系,包括5个一级指标(综合素质、能力和个人愿望,教育和工作背景,个人职业发展能力,全科医疗工作能力,全科医学教学能力)和57个二级指标.两轮咨询的专家积极系数均为100%,专家权威程度均为0.85,指标重要性协调系数分别为0.190和0.225(均P<0.01).结论 采用德尔菲专家咨询法初步建立了上海市社区全科师资基本能力评估指标体系,多方位、多角度评价社区全科师资应当具备的基本能力,可作为将来设立社区全科师资准入标准的基础.%Objective To explore establishment of indicator system to evaluate basic capacities of trainers of training for community general practitioners (GPs) to standardize their capacity building and management.Methods Questionnaire survey was conducted among 190 trainers of training for community health managers and GPs who were involved in community health-care and health-care service management in 12 districts of Shanghai to investigate what basic capacities the trainers should have.Delphi expert consultation method was used to construct an evaluation indicator system.Firstly, an evaluation form was formulated based on the preceding questionnaire.Then, two rounds of expert consultation were carried out with 28 experts specialized in general practice

  2. Establishment of multi-drug resistance human B-cell lymphoma cell line BJAB/ADR and preliminary research of its drug-resistance mechanism%人类B细胞淋巴瘤耐药细胞株BJAB/ADR的建立及其耐药机制的初步研究

    Institute of Scientific and Technical Information of China (English)

    鲍世琦; 姜琳琳; 张晓龙; 李真真; 邵晓枫; 齐怀丰; 杨雨琪; 熊冬生

    2014-01-01

    目的 建立人类淋巴瘤B JAB多药耐药细胞株BJAB/ADR,并初步研究其耐药机制.方法 采用多柔比星浓度梯度递增法建立人类B细胞淋巴瘤耐药细胞模型BJAB/ADR,观察其生长规律并绘制细胞生长曲线;用四甲基偶氮唑蓝(MTT)法鉴定耐药细胞株对多种化疗药物的耐药性并计算耐药指数;提取耐药细胞株RNA,实时定量聚合酶链反应(PCR)法检测相关耐药基因MDR1 mRNA的表达;流式细胞术检测细胞表面P糖蛋白(Pgp)的表达;通过罗丹明外排实验,检测Pgp功能.结果 成功建立B细胞淋巴瘤耐药细胞模型BJAB/ADR,并在160 ng/ml多柔比星溶液中稳定生长,耐药细胞较敏感细胞生长缓慢,细胞形态无明显变化.MTT检测结果表明BJAB/ADR细胞对多柔比星的耐药指数为43倍,同时对柔红霉素、依托泊苷、高三尖杉酯碱(HHT)及米托蒽醌(MX)也具有一定的耐药性.实时定量PCR结果表明,耐药细胞BJAB/ADR MDRl mRNA明显高于药物敏感细胞BJAB(P< 0.01).流式细胞术检测结果显示,耐药细胞表面Pgp高表达;罗丹明外排实验表明Pgp对多柔比星具有外排功能,使B JAB/ADR细胞获得耐药特性.结论 建立了人类B细胞淋巴瘤的耐药细胞株BJAB/ADR,其对多柔比星耐药性稳定,并呈现多药耐药细胞的基本生物学特性,为进一步研究肿瘤多药耐药发生的机制及逆转耐药提供有利的模型.%Objective To establish human multi-drug resistance (MDR) B-cell lymphoma cell line BJAB/ADR and investigate its biological characteristics.Methods Human B-cell lymphoma MDR cell line BJAB/ADR was induced by exposure to increasing dose of adriamycin.The growing features of BJAB/ADR were observed and cell growth was measured,IC50 of antitumor agents was evaluated by MTT assay.The expression of MDR1 mRNA was determined with real-time PCR,FACS was applied to study the expression of MDR protein P-glycoprotein (Pgp) and Rhodamine 123R efflux assay was used to

  3. How to establish a company

    OpenAIRE

    Konečný, Viktor

    2008-01-01

    This diploma thesis is focused on a franchising business establishment, particularly on the business establishment of a fictive coffe house which could become a well known franchising concept on the Czech market. Primary advantage of franchise compared to the other types of business cooperation is mainly risk reduction for the investor (franchisee) who obtains proven model of the business. For the franchisor the franchise means an easier way how to widen his business without taking higher lab...

  4. Development and preliminary validation of the Opioid Abuse Risk Screener.

    Science.gov (United States)

    Henrie-Barrus, Patricia; Averill, Lynnette A; Sudweeks, Richard R; Averill, Christopher L; Mota, Natalie

    2016-01-01

    Prescription opioid drug abuse has reached epidemic proportions. Individuals with chronic pain represent a large population at considerable risk of abusing opioids. The Opioid Abuse Risk Screener was developed as a comprehensive self-administered measure of potential risk that includes a wide range of critical elements noted in the literature to be relevant to opioid risk. The creation, refinement, and preliminary modeling of the item pool, establishment of preliminary concurrent validity, and the determination of the factor structure are presented. The initial development and validation of the Opioid Abuse Risk Screener shows promise for effective risk stratification.

  5. Development and preliminary validation of the Opioid Abuse Risk Screener

    Directory of Open Access Journals (Sweden)

    Patricia Henrie-Barrus

    2016-05-01

    Full Text Available Prescription opioid drug abuse has reached epidemic proportions. Individuals with chronic pain represent a large population at considerable risk of abusing opioids. The Opioid Abuse Risk Screener was developed as a comprehensive self-administered measure of potential risk that includes a wide range of critical elements noted in the literature to be relevant to opioid risk. The creation, refinement, and preliminary modeling of the item pool, establishment of preliminary concurrent validity, and the determination of the factor structure are presented. The initial development and validation of the Opioid Abuse Risk Screener shows promise for effective risk stratification.

  6. Preliminary experience on the implementation of computed tomography (CT)-based image guided brachytherapy (IGBT) of cervical cancer using high-dose-rate (HDR) Cobalt-60 source in University of Malaya Medical Centre (UMMC)

    Science.gov (United States)

    Jamalludin, Z.; Min, U. N.; Ishak, W. Z. Wan; Malik, R. Abdul

    2016-03-01

    This study presents our preliminary work of the computed tomography (CT) image guided brachytherapy (IGBT) implementation on cervical cancer patients. We developed a protocol in which patients undergo two Magnetic Resonance Imaging (MRI) examinations; a) prior to external beam radiotherapy (EBRT) and b) prior to intra-cavitary brachytherapy for tumour identification and delineation during IGBT planning and dosimetry. For each fraction, patients were simulated using CT simulator and images were transferred to the treatment planning system. The HR-CTV, IR-CTV, bladder and rectum were delineated on CT-based contouring for cervical cancer. Plans were optimised to achieve HR-CTV and IR-CTV dose (D90) of total EQD2 80Gy and 60Gy respectively, while limiting the minimum dose to the most irradiated 2cm3 volume (D2cc) of bladder and rectum to total EQD2 90Gy and 75Gy respectively. Data from seven insertions were analysed by comparing the volume-based with traditional point- based doses. Based on our data, there were differences between volume and point doses of HR- CTV, bladder and rectum organs. As the number of patients having the CT-based IGBT increases from day to day in our centre, it is expected that the treatment and dosimetry accuracy will be improved with the implementation.

  7. Preliminary experience with MRA in evaluating the degree of carotid stenosis and plaque morphology using high-resolution sequences after gadofosveset trisodium (Vasovist) administration: comparison with CTA and DSA.

    Science.gov (United States)

    Anzidei, M; Napoli, A; Geiger, D; Cavallo Marincola, B; Zini, C; Zaccagna, F; Di Paolo, P; Catalano, C; Passariello, R

    2010-06-01

    The authors performed a preliminary study with blood-pool contrast-enhanced magnetic resonance angiography (MRA) in evaluating the degree of carotid artery stenosis and plaque morphology, comparing the diagnostic performance of first-pass (FP) and steady-state (SS) acquisitions with 64-slice computed tomography angiography (CTA) and using digital subtraction angiography (DSA) as the reference standard. Twenty patients with >or=50% carotid artery stenosis at Doppler sonography underwent blood-pool contrast-enhanced MRA, CTA and DSA. Two independent radiologists evaluated MRA and CTA examinations to assess the degree of stenosis and characterise plaque morphology. Accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated for FP, SS and CTA. The McNemar and Wilcoxon tests were used to determine significant differences (p0.05). Blood-pool contrast-enhanced MRA with SS sequences allow improved diagnostic evaluation of the degree of carotid stenosis and plaque morphology compared with FP and is substantially equal to CTA and DSA.

  8. Towards Establishing Capacity for Biological Dosimetry at Ghana Atomic Energy Commission

    Science.gov (United States)

    Achel, Daniel Gyingiri; Achoribo, Elom; Agbenyegah, Sandra; Adaboro, Rudolph M.; Donkor, Shadrack; Adu-Bobi, Nana A. K.; Agyekum, Akwasi A.; Akuamoa, Felicia; Tagoe, Samuel N.; Kyei, Kofi A.; Yarney, Joel; Serafin, Antonio; Akudugu, John M.

    2016-01-01

    The aim of this study was not only to obtain basic technical prerequisites for the establishment of capacity of biological dosimetry at the Ghana Atomic Energy Commission (GAEC) but also to stimulate interest in biological dosimetry research in Ghana and Sub-Saharan Africa. Peripheral blood from four healthy donors was exposed to different doses (0–6 Gy) of gamma rays from a radiotherapy machine and lymphocytes were subsequently stimulated, cultured, and processed according to standard protocols for 48–50 h. Processed cells were analyzed for the frequencies of dicentric and centric ring chromosomes. Radiation dose delivered to the experimental model was verified using GafChromic® EBT films in parallel experiments. Basic technical prerequisites for the establishment of capacity of biological dosimetry in the GAEC have been realized and expertise in the dicentric chromosome assay consolidated. We successfully obtained preliminary cytogenetic data for a dose-response relationship of the irradiated blood lymphocytes. The data strongly indicate the existence of significant linear (α) and quadratic (β) components and are consistent with those published for the production of chromosome aberrations in comparable absorbed dose ranges. PMID:28217279

  9. Preliminary Design of IHTS Cold Trap for PGSFR

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jewhan; Lee, Taeho [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-05-15

    The main impurities in liquid sodium of the IHTS are oxygen and hydrogen. These impurities form oxides and hydrides with sodium and cause various problems. In order to eliminate the impurities the Cold Trap is installed in the loop. The life and capacity of the IHTS cold Trap depends the amount of impurities. For IHTS loop, the hydrogen has been identified as the major contamination from Steam Generator (SG) during the normal operation. In this study, the sizing of cold trap based on the source rate of hydrogen from SG from past experiences was conducted. Empirical relations among different variables were adopted to establish the temperature distribution, pressure drops, flow rates and geometries for the cold trap and its associated component. In this study, the IHTS cold trap for normal operation has been analyzed and the preliminary design of corresponding cold trap and economizer has been carried out. For further detailed design, R and D on basic sodium technology will be essential to optimize the Cold Trap.

  10. Preliminary study on mechanics-based rainfall kinetic energy

    Directory of Open Access Journals (Sweden)

    Yuan Jiuqin Ms.

    2014-09-01

    Full Text Available A raindrop impact power observation system was employed to observe the real-time raindrop impact power during a rainfall event and to analyze the corresponding rainfall characteristics. The experiments were conducted at different simulated rainfall intensities. As rainfall intensity increased, the observed impact power increased linearly indicating the power observation system would be satisfactory for characterizing rainfall erosivity. Momentum is the product of mass and velocity (Momentum=MV, which is related to the observed impact power value. Since there is no significant difference between momentum and impact power, observed impact power can represent momentum for different rainfall intensities. The relationship between momentum and the observed impact power provides a convenient way to calculate rainfall kinetic energy. The value of rainfall kinetic energy based on the observed impact power was higher than the classic rainfall kinetic energy. The rainfall impact power based kinetic energy and the classic rainfall kinetic energy showed linear correlation, which indicates that the raindrop impact power observation system can characterize rainfall kinetic energy. The article establishes a preliminary way to calculate rainfall kinetic energy by using the real-time observed momentum, providing a foundation for replacing the traditional methods for estimating kinetic energy of rainstorms.

  11. A Preliminary Jupiter Model

    CERN Document Server

    Hubbard, W B

    2016-01-01

    In anticipation of new observational results for Jupiter's axial moment of inertia and gravitational zonal harmonic coefficients from the forthcoming Juno orbiter, we present a number of preliminary Jupiter interior models. We combine results from ab initio computer simulations of hydrogen-helium mixtures, including immiscibility calculations, with a new nonperturbative calculation of Jupiter's zonal harmonic coefficients, to derive a self-consistent model for the planet's external gravity and moment of inertia. We assume helium rain modified the interior temperature and composition profiles. Our calculation predicts zonal harmonic values to which measurements can be compared. Although some models fit the observed (pre-Juno) second- and fourth-order zonal harmonics to within their error bars, our preferred reference model predicts a fourth-order zonal harmonic whose absolute value lies above the pre-Juno error bars. This model has a dense core of about 12 Earth masses, and a hydrogen-helium-rich envelope with...

  12. A Preliminary Jupiter Model

    Science.gov (United States)

    Hubbard, W. B.; Militzer, B.

    2016-03-01

    In anticipation of new observational results for Jupiter's axial moment of inertia and gravitational zonal harmonic coefficients from the forthcoming Juno orbiter, we present a number of preliminary Jupiter interior models. We combine results from ab initio computer simulations of hydrogen-helium mixtures, including immiscibility calculations, with a new nonperturbative calculation of Jupiter's zonal harmonic coefficients, to derive a self-consistent model for the planet's external gravity and moment of inertia. We assume helium rain modified the interior temperature and composition profiles. Our calculation predicts zonal harmonic values to which measurements can be compared. Although some models fit the observed (pre-Juno) second- and fourth-order zonal harmonics to within their error bars, our preferred reference model predicts a fourth-order zonal harmonic whose absolute value lies above the pre-Juno error bars. This model has a dense core of about 12 Earth masses and a hydrogen-helium-rich envelope with approximately three times solar metallicity.

  13. Preliminary research on the establishment of non-invasive model of radiation-induced oral mucositis in rats by 60 Coγ-rays irradiation%60 Coγ射线照射大鼠建立放射性口腔黏膜炎模型的初步研究

    Institute of Scientific and Technical Information of China (English)

    刘礼; 陶人川; 雍翔智; 蒋兰岚; 曾启新

    2016-01-01

    目的:建立大鼠放射性口腔黏膜炎模型,观察并分析黏膜组织炎症变化过程。方法:选择SD大鼠45只,随机分为9组:空白对照组;实验组8组均用60 Coγ射线以35 Gy剂量单次照射口鼻部。观察大鼠口腔黏膜状况,对炎症期间拒食的大鼠进行灌注流食喂养。分别于放射后1、3、5、7、10、14、21及28 d处死1组实验组大鼠,对照组于28 d处死,取口腔黏膜组织进行HE染色和光镜下观察。结果:放射后5~6 d,大鼠口腔黏膜出现红肿伴有小面积溃疡;7~8 d小溃疡逐渐融合成大面积溃疡,并持续到9~13 d;14 d开始,溃疡逐渐缩小并愈合;21~28 d溃疡完全愈合。 HE染色显示放射后第5 d,黏膜下层出现大量炎性细胞浸润,但上皮层连续完整;第7、10 d,上皮层崩解、脱落;第14 d溃疡底部可见新生肉芽组织及新生毛细血管;第21、28 d,溃疡处有新的上皮组织出现,基底层排列紧密。结论:经60 Coγ射线照射成功建立放射性口腔黏膜炎大鼠模型,炎症从5~8 d开始,第9~13 d达到高峰,14 d左右开始缓解恢复,21~28 d恢复正常。%Objective:To establish a non-invasive model of radiation-induced oral mucositis( RTOM) in rats and ob-serve the dynamic process of the occurrence,development and healing of mucosal inflammation. Methods:After randomly di-viding 45 SD rats into 9 groups,one group was maintained as a blank control group,while each rat of the other 8 groups re-ceived an irradiation of single 35 Gy dose of 60 Coγ-rays. The condition of the oral mucosal was observed everyday. Each group of experimental rats was sacrificed at the 1 st , 3 rd , 5 th , 7 th , 10 th , 14 th , 21 st and 28 th day after the irradiation respectively. However,the control group of rats were sacrificed only on the 28th day. Oral mucosa tissues of the dead rats were harvested. The samples underwent HE staining for histological

  14. Establishment and preliminary application of single-tube nested realtime PCR in detecting Mycobacte-rium leprae%单管巢式实时 PCR 检测麻风杆菌方法的建立及初步应用

    Institute of Scientific and Technical Information of China (English)

    覃晓琳; 百顺; 郑和平; 黄进梅; 薛耀华; 曾维英; 吴兴中; 欧江丽; 蓝银苑; 唐三梅; 方铭恒

    2014-01-01

    Objective: To detect the sensitivity of single-tube nested realtime PCR in detecting Mycobacte-rium leprae. Methods: The primers and probe were designed based on the hsp18 gene of Mycobacterium lep-rae. The single-tube nested realtime PCR was established and the sensitivity and specificity were compared with acid-fast staining and ordinary PCR. Results: The sensitivity of the single-tube nested realtime PCR for detecting Mycobacterium leprae was 2.1fg of plasmid DNA, which was 10 times more sensitive than that in the normal PCR. There was non-cross reactivity with other 8 Non-Mycobacterium leprae. Intra relative standard deviation (RSD) was 0.24%-1.08% and inter RSD was 0.09% -2.8%. The sensitivity of acid-fast staining, normal and single-tube nested PCR in detecting 54 suspected samples of leprosy was 81.3% (26/ 32), 87.5%(28/ 32) and 96.9% (31/ 32), respectively. Conclusion: The single-tube nested realtime PCR method in detecting Mycobacterium leprae is more sensitive and specific.%目的::明确单管巢式实时 PCR 检测麻风杆菌的特异性、灵敏性和重复性。方法:以麻风杆菌 hsp18基因为靶基因设计引物和探针,建立单管巢式实时 PCR 方法检测麻风杆菌并与抗酸染色及普通 PCR 进行特异性和灵敏性的比较。结果:单管巢式实时 PCR 检测下限为2.1 fg 质粒 DNA,普通PCR 为21 fg 质粒 DNA,敏感性高10倍;与8种非麻风杆菌无交叉反应;批内相对标准偏差(RSD)为0.24%~1.08%,批间 RSD 为0.09%~2.8%。对比检测54例麻风疑似标本中,抗酸染色、普通 PCR 和单管巢式实时 PCR 的敏感性分别为81.3%(26/32)、87.5%(28/32)和96.9%(31/32)。结论:单管巢式实时 PCR 特异性强、敏感性高且重复性好。

  15. Preliminary analysis of insertion site of transgenic wheat exogenous gene and the establishment of detection method%转基因小麦外源基因插入位点初步分析及检测方法的建立

    Institute of Scientific and Technical Information of China (English)

    段晓亮; 许兰杰; 刘志勇; 梁荣奇

    2014-01-01

    利用染色体步移(genome -walking)原理和巢式 PCR 方法,对转基因小麦外源基因 sGNA 插入位点的序列特征进行了分析,并以此建立了 sGNA 基因转化事件特异性检测的方法。根据 sGNA 基因的核苷酸序列设计特异引物,利用 Takara 公司提供的简并随机引物,通过染色体步移法扩增到了转sGNA 基因株系 zy2-18的插入位点的边界序列,分析得到的边界序列可知,外源基因片段是通过部分同源重组的方式与小麦基因组进行整合的,整合位点位于 A 染色体组。检测结果显示携带外源基因 sGNA 的质粒在与小麦基因组整合的过程中发生了剪切,且 Ubi 启动子与 bar 基因被切除,保留了两个串联的 NOS 基因,且在4500~4520 bp 区间发生了重组后的缺失,而在4786~4810 bp 区间有一段碱基序列插入,导致插入区段的小麦基因组序列发生重排,初步分析外源基因是通过同源重组的方式进行整合的。通过验证,证明了插入位点信息的准确性,并初步判断插入位点位于小麦 A 染色体组。因此,随机引物法 genome -walking 可以作为转基因小麦安全检测及身份识别的有效方法。%The sequence character of insertion site of transgenic wheat exogenous gene sGNA was analyzed by genome -walking and the Nested -PCR methods,and the method of detection of sGNA gene trans-form event specificity was established.The random primers were supplied by Takara and the specific primers were designed based on the sGNA sequence.The boundary sequences of sGNA were cloned by genome -walking,and located on genome A by the homologous recombination.The Ubi promoter and bar gene of the plasmid with exogenous gene sGNA were cut off during the integration process,and two series of NOS genes were remained,the deletion was resulted in 4 500 ~4 520 bp,and insertion of a seg-ment of base sequence was discovered between 4 786 bp to 4810 bp

  16. 猪葡萄球菌脱落毒素多重PCR检测方法的建立与初步应用%Establishment and preliminary application of a multiplex PCR assay for detection of exfoliative toxin of Staphylococcus hyicus

    Institute of Scientific and Technical Information of China (English)

    陈亚强; 郝永清; 张乐宜; 蔡汝健; 宋长绪

    2012-01-01

    In this study six pairs of primers were designed and synthesized according to the reported sequences of six different exfoliative toxin types of Staphylococcus hyicus in GenBank.A multiplex PCR assay was established after specific,sensitive and accuracy tests.Nine clinical isolates of Staphylococcus hyicus were detected by this multiplex PCR assay,23S rDNA(size of 662 bp) were amplified from all of the nine strains as expected.At the same time specific fragments targeted EXHA(size of 316 bp,2 strains),EXHC(size of 525 bp,2 strains),Shet-A(size of 814 bp,2 strains) genes were amplified from six isolates,respectively.None of the specific fragments of toxin genes were amplified from the other three isolates,indicating no virulence of these three isolates.The above results were correspondent to the results of biochemical identification and single PCR detection and sequencing.The results showed that this new method was not only rapid and convenient,but also highly specific,sensitive and repeatable.It can be used for detection of exudative epidermitis and the fast identification of Staphylococcus hyicus.%根据GenBank已发表的猪葡萄球菌的6种脱落毒素基因序列,设计合成了6对相应的特异性引物,通过特异性、敏感性和重复性试验建立了可行的多重PCR检测方法。用该方法对临床分离到的9株猪葡萄球菌进行检测,均扩增出了与预期大小相符的23SrDNA(662bp)条带;同时,其中6株分别扩增出了EXHA(316bp,2株)、EXHC(525bp,2株)和Shet-A(814bp,2株)基因特异性条带;另外3株均未扩增出任何毒素基因特异性条带,鉴定为无毒力菌株,以上结果与生化鉴定及单一PCR检测测序结果一致。结果表明,本试验所建立的多重PCR方法不仅操作快速方便、节约试验成本,而且具有高度特异性、敏感性和良好的重复性,可用于仔猪渗出性皮炎的诊断和猪葡萄球菌的快速鉴定。

  17. Neutrinoless double-beta decay search with CUORE and CUORE-0 experiments

    Directory of Open Access Journals (Sweden)

    Moggi N.

    2015-01-01

    Full Text Available The Cryogenic Underground Observatory for Rare Events (CUORE is an upcoming experiment designed to search for the neutrinoless double-beta decays. Observation of the process would unambiguously establish that neutrinos are Majorana particles and provide information on their absolute mass scale hierarchy. CUORE is now under construction and will consist of an array of 988 TeO2 crystal bolometers operated at 10 mK, but the first tower (CUORE-0 is already taking data. The experimental techniques used will be presented as well as the preliminary CUORE-0 results. The current status of the full-mass experiment and its expected sensitivity will then be discussed.

  18. 羊环形泰勒虫单管套式PCR检测方法的建立及初步应用%Establishment and Preliminary Application of a Single-tube Nested PCR Assay for Detection of Goat Theileria annulata

    Institute of Scientific and Technical Information of China (English)

    李丽; 王书全; 费东亮

    2012-01-01

    To develop a single-tube nested PCR assay for detection of goat-derived Theileria annulata. According to the published Theileria annulata Tams1 gene sequence in Genbank, two pairs of primers were designed to develop nested PCR assay for detecting the disease caused by goat Theileria annulata. The results of verification experiments were shown that the targeted gene fragment was 476 bp in length and homology of nested PCR product was 93% to 98%, and this detection method had no cross reaction with Toxoplasma, Neospora caninum, Eimeria, Eperythrozoon suis, and the sensitivity of the assay reached to 12 fg of DNA. The 40.4% of positive rate in 127 clinical sample were detected by the single-tube nested PCR assay, higher than those by routine PCR and microscopic examination. The results revealed that the single-tube nested PCR assay had higher specificity, sensitivity and it could be an effective detection method of goat Theileria annulata.%为了建立羊环形泰勒虫单管套式PCR检测方法并初步应用于临床检测.根据GenBank上发表的环形泰勒虫Tams1基因序列,设计内、外2对特异性引物,进行单管套式PCR检测方法研究,并进行了特异性、敏感性试验及临床应用试验.结果表明:该检测方法能够扩增的基因片段大小为476 bp,与GenBank收录的相关序列同源性高达93%~98%,而与附红细胞体、新孢子虫、艾美耳球、弓形虫RH株相关病原基因组均无交叉反应,能够检测出DNA的最小量为12fg.并对57份临床样品进行了检测,检测阳性率为40.4%,高于常规PCR和血涂片镜检测,表明该检测方法具有较高的敏感性,可用于羊环形泰勒虫感染的早期诊断,有较好的临床应用价值.

  19. Early evaluation of cerebral metabolic rate of glucose (CMRglu) with {sup 18}F-FDG PET/CT and clinical assessment in idiopathic normal pressure hydrocephalus (INPH) patients before and after ventricular shunt placement: preliminary experience

    Energy Technology Data Exchange (ETDEWEB)

    Calcagni, Maria Lucia; Lavalle, Mariadea; Leccisotti, Lucia; Giordano, Alessandro [Universita Cattolica del Sacro Cuore, Institute of Nuclear Medicine, Rome (Italy); Mangiola, Annunziato; De Bonis, Pasquale; Anile, Carmelo [Universita Cattolica del Sacro Cuore, Institute of Neurosurgery, Rome (Italy); Indovina, Luca [Universita Cattolica del Sacro Cuore, Institute of Physics, Rome (Italy); Marra, Camillo [Universita Cattolica del Sacro Cuore, Institute of Neurology, Rome (Italy); Pelliccioni, Armando [Istituto Nazionale per l' Assicurazione contro gli Infortuni sul Lavoro (INAIL), Rome (Italy)

    2012-02-15

    We evaluated the relationships between the cerebral metabolic rate of glucose (CMRglu) measured by dynamic {sup 18}F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) and the clinical and neuropsychological assessment before and after the surgical procedure in idiopathic normal pressure hydrocephalus (INPH) patients. Eleven selected INPH patients underwent clinical assessment (modified Rankin scale, Krauss scale, Larsson categorization system and Stein-Langfitt scale), cognitive evaluation (Mini-Mental State Examination, MMSE) and dynamic {sup 18}F-FDG PET/CT scan 3 days before and 1 week after ventricular shunt placement. After shunting, the global CMRglu significantly increased (2.95 {+-} 0.44 vs 4.38 {+-} 0.68, p = 10{sup -7}) in all INPH patients with a mean percentage value of 48.7%. After shunting, no significant change was found in the Evans ratio whereas a significant decrease in all clinical scale scores was observed. Only a slight reduction in the MMSE was found. After shunting, a significant correlation between the global CMRglu value and clinical assessment was found (R {sup 2} = 0.75, p = 0.024); indeed all clinical scale scores varied (decreasing) and the CMRglu value also varied (increasing) in all INPH patients. Our preliminary data show that changes in the CMRglu are promptly reversible after surgery and that there is a relationship between the early metabolic changes and clinical symptoms, independently from the simultaneous changes in the ventricular size. The remarkable and prompt improvement in the global CMRglu and in symptoms may also have important implications for the current concept of ''neuronal plasticity'' and for the cells' reactivity in order to recover their metabolic function. (orig.)

  20. Horticultural therapy as a measure for recovery support of regional community in the disaster area: a preliminary experiment for forty five women who living certain region in the coastal area of Miyagi Prefecture.

    Science.gov (United States)

    Kotozaki, Yuka

    2014-01-01

    Three years have passed since the earthquake, in the coastal areas in the disaster area, by population transfer or the like from the temporary housing, the importance of the regeneration and revitalization of the local community has been pointed out. This study performed a preliminary study to aim at the psychological inspection about an effect of the horticultural therapy as the means of the local community reproduction support of the disaster area. Forty five women who are living in the coastal area of Miyagi Prefecture participated in this study. They experienced the Great East Japan earthquake in 2011 and suffered some kind of damage caused by the earthquake. The participants were assigned to two groups, the intervention group and the control group, via a random draw using a computer. The HI group attended the horticultural therapy intervention (HT intervention) sessions for 16 weeks. The HT intervention was designed in collaboration with a horticultural therapist and clinical psychologists. This intervention comprised a total of 16 weekly sessions (120 min each) at the community center and 15 minutes per day at participants' homes. We used five psychological measures for an intervention evaluation. The HI group showed a significant increase in post- intervention SCI-2 total scores, post- intervention SCI-2 membership scores, post-intervention SCI-2 influence scores, post- intervention SCI-2 meeting needs scores, post- intervention SCI-2 shared emotional connection scores, and post- intervention RSES score. We believe that these results suggest the effectiveness of the horticultural therapy as the means of the local community reproduction.

  1. 应用化学专业无机化学实验教学改革的探索%Preliminary Exploration of the Teaching Reform on the Applied Chemistry Specialty Inorganic Chemistry Experiment

    Institute of Scientific and Technical Information of China (English)

    赵艳; 赵蕾; 赵红梅; 秦向东

    2014-01-01

    对应用化学专业无机化学实验教学进行了深入的分析和思考,探讨了教学内容及教学手段的改革,探索了建设绿色化实验的主要措施,以绿色化学理念为指导原则,结合教学实际情况,探索无机化学实验教学各环节的绿色化方案,提出实验微型化或小型化等绿色化实验策略,强调实验教学手段的绿色化,从而培养学生的环保意识,为建设绿色化无机化学实验提供参考。%Applied chemistry inorganic chemistry experiment teaching was conducted in -depth analysis and reflection, the reform of teaching contents and teaching methods were discussed , and the main measures of building green experiment were explored.Inorganic chemistry experiment teaching taking green chemical concepts as guidance , combining with teaching practice , greening scheme of experiment teaching of inorganic in each section of teaching process was explored.A series of experimental methods to settle the question , such as promoting microscale or small experiment , were put forward.It was important to emphasize greening of experiment teaching approach to cultivate student's consciousness of environment protection.The study can provide a reference for the construction of green inorganic chemistry.

  2. 人大肠癌多药耐药细胞LoVo/5-FU的建立及其生物学特性的初步研究%Establishment of multidrug-resistant human colorectal cancer cell line LoVo/5-FU:a preliminary study of biological characterization

    Institute of Scientific and Technical Information of China (English)

    姚学清; 卿三华; 杨洋; 秦斌; 袁玮; 夏琼

    2001-01-01

    目的建立人大肠癌LoVo细胞多药耐药细胞株LoVo/5-FU,并探讨其生物学特性及耐药机制。方法人大肠癌细胞系LoVo在体外经2.5μg/ml5-氟尿嘧啶(5-FU)作用,成功诱导LoVo/5-FU耐药细胞株。体外细胞毒性实验观察它们对5-FU、丝裂酶素(MMC)、阿霉素(ADM)、顺铂(DDP)、氨甲喋呤(MTX)和阿糖胞苷(AraC)等6种药物的敏感性。用噻唑蓝(MTT)法、光镜及扫描电镜观察两种细胞形态及结构并绘制出细胞体外生长曲线。免疫组化LSAB法检测细胞中P26-Bcl-2的表达。应用原位DNA末端转移酶标记法检测5-FU在两种细胞中诱导的细胞凋亡。结果LoVo/5-FU细胞株对5-FU、MMC和ADM均有耐药性,且对5-FU的耐药程度较亲本细胞提高。与亲本细胞相比,耐药细胞株生长慢,倍增期延长,汇合密度低,异型性明显。免疫组化LSAB法提示,LoVo/5-FU细胞的凋亡与P26-Bcl-2过度表达有关。LoVo细胞原位DNA末端转移酶标记阳性率高于LoVo/5-FU。结论LoVo/5-FU多药耐药细胞株耐药性稳定,在相同条件下与敏感细胞株LoVo相比,细胞凋亡受到抑制,提示LoVo/5-FU细胞可抵抗5-FU诱导的细胞凋亡,其机制可能与P26-Bcl-2过度表达密切相关。%Objective To investigate the changes in biological properties ofthe multidrug-resistant (MDR) variant of human colorectal cancer LoVo cell lines and to explore the mechanism for MDR generation in human colorectal cancer cells. Method A MDR variant of human colorectal cancer to 5-FU treatment, LoVo/5-FU, was established in vitro by exposing parent LoVo cells to pulse treatment with 2.5 μg/ml 5-FU over a period of 6 months. Its sensitivity to 6 antitumor agents was observed by MTT method, and morphological observation under light microscope and electron microscope of both LoVo and LoVo/5-FU cells were performed. Bcl-2 gene expressions in two cells were assayed immunohischemically. Results The Lo

  3. Establishment and preliminary application of dengue virus envelope domain Ⅲ IgG antibody capture enzyme-linked immuno-absorbent assay%登革病毒包膜蛋白Ⅲ区IgG抗体捕获酶联免疫吸附试验的建立及应用

    Institute of Scientific and Technical Information of China (English)

    胡冬梅; 蔡建飘; 王大虎; 狄飚; 丘立文; 王压娣; 陈月; 丁细霞; 车小燕

    2013-01-01

    Objective To establish a highly sensitive and specific assay to detect dengue virus (DENV) envelope protein domain Ⅲ (ED Ⅲ) IgG antibody,and to explore its value in the diagnosis and seroepidemiological survey of dengue.Methods The DENV ED Ⅲ IgG antibody capture ELISA was developed using the recombinant full-length DENV ED Ⅲ,which was prepared by Pichia yeast expression system as the capture antigen.The serum samples were collected from the same group of 35 DENV-1 patients of primary infection during disease period in 2006 and their follow-up phase in 2010; and the sensitivity of the assay was compared to that of the commercial Panbio DENV IgG ELISA.Results The sensitivity of DENV ED Ⅲ IgG ELISA in detecting the serum samples from disease period and follow-up phase was 87%(20/23) and 94% (33/35),respectively; whereas the sensitivity of Panbio DENV IgG ELISA was 71%(25/35) and 0,respectively.The sensitivity of DENV EDⅢ IgG ELISA in detecting the serum samples from both periods was similar,without statistical significance (x2 =0.946,P =0.331).For serum samples from disease period,the sensitivity of DENV ED Ⅲ IgG ELISA was comparable with that of Panbio DENV IgC ELISA (x2 =1.924,P =0.165).However,DENV ED Ⅲ IgG ELISA demonstrated a significantly higher sensitivity than Panbio DENV IgG ELISA in detecting the serum samples from follow-up phase (x2 =62.432,P =0.000).Conclusion DENV ED Ⅲ IgG capture ELISA is highly sensitive in detecting IgG in the serum samples from either disease period or follow-up phase.This method might be a promising alternative for diagnosis and seroepidemiologic survey of dengue.%目的 建立一种高度敏感和特异的登革病毒(dengue virus,DENV)包膜蛋白Ⅲ区(envelope protein domain Ⅲ,ED Ⅲ)IgG抗体的检测方法,并探索这种方法在登革热诊断和血清流行病学调查中的应用价值.方法 以毕赤酵母表达系统制备的重组全长DENV EDⅢ作为抗原,建立DENV EDⅢIgG抗体捕

  4. Acoustic comfort in eating establishments

    DEFF Research Database (Denmark)

    Svensson, David; Jeong, Cheol-Ho; Brunskog, Jonas

    2014-01-01

    The subjective concept of acoustic comfort in eating establishments has been investigated in this study. The goal was to develop a predictive model for the acoustic comfort, by means of simple objective parameters, while also examining which other subjective acoustic parameters could help explain...... the feeling of acoustic comfort. Through several layers of anal ysis, acoustic comfort was found to be rather complex, and could not be explained entirely by common subjective parameters such as annoyance, intelligibility or privacy. A predictive model for the mean acoustic comfort for an eating establishment...

  5. Establishing operations and the mand.

    Science.gov (United States)

    Michael, J

    1988-01-01

    In Verbal Behavior Skinner identifies a small number of elementary verbal relations, one of which is the mand. Because its introduction is at first in terms of unlearned motivative variables, and because the mand's relation to prior controlling events is quite complex, its general significance has probably been underestimated. An extensive treatment of establishing operations, including the warning and the blocked-response conditioned establishing operations is provided, followed by a description of the mand in terms of such operations. The importance of the mand for language training programs is suggested, as well as the reasons why it is typically neglected in such programs.</