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Sample records for preliminary analyses show

  1. Preliminary Analyses of Beidou Signal-In Anomaly Since 2013

    Science.gov (United States)

    Wu, Y.; Ren, J.; Liu, W.

    2016-06-01

    As BeiDou navigation system has been operational since December 2012. There is an increasing desire to use multiple constellation to improve positioning performance. The signal-in-space (SIS) anomaly caused by the ground control and the space vehicle is one of the major threats to affect the integrity. For a young Global Navigation Satellite System, knowledge about SIS anomalies in history is very important for not only assessing the SIS integrity performance of a constellation but also providing the assumption for ARAIM (Advanced Receiver Autonomous Integrity Monitoring). In this paper, the broadcast ephemerides and the precise ones are pre-processed for avoiding the false anomaly identification. The SIS errors over the period of Mar. 2013-Feb. 2016 are computed by comparing the broadcast ephemerides with the precise ones. The time offsets between GPST (GPS time) and BDT (BeiDou time) are estimated and removed by an improved estimation algorithm. SIS worst-UREs are computed and a RMS criteria are investigated to identify the SIS anomalies. The results show that the probability of BeiDou SIS anomalies is in 10-3 level in last three years. Even though BeiDou SIS integrity performance currently cannot match the GPS integrity performances, the result indicates that BeiDou has a tendency to improve its integrity performance.

  2. Advanced behavioral analyses show that the presence of food causes subtle changes in C. elegans movement

    Directory of Open Access Journals (Sweden)

    Nicholas eAngstman

    2016-03-01

    Full Text Available As a widely used and studied model organism, C. elegans worms offer the ability to investigate implications of behavioral change. Although investigation of C. elegans behavioral traits has been shown, analysis is often narrowed down to measurements based off a single point, and thus cannot pick up on subtle behavioral and morphological changes. In the present study videos were captured of four different C. elegans strains grown in liquid cultures and transferred to NGM-agar plates with an E. coli lawn or with no lawn. Using an advanced software, WormLab, the full skeleton and outline of worms were tracked to determine whether the presence of food affects behavioral traits. In all seven investigated parameters, statistically significant differences were found in worm behavior between those moving on NGM-agar plates with an E. coli lawn and NGM-agar plates with no lawn. Furthermore, multiple test groups showed differences in interaction between variables as the parameters that significantly correlated statistically with speed of locomotion varied. In the present study, we demonstrate the validity of a model to analyze C. elegans behavior beyond simple speed of locomotion. The need to account for a nested design while performing statistical analyses in similar studies is also demonstrated. With extended analyses, C. elegans behavioral change can be investigated with greater sensitivity, which could have wide utility in fields such as, but not limited to, toxicology, drug discovery, and RNAi screening.

  3. Advanced Behavioral Analyses Show that the Presence of Food Causes Subtle Changes in C. elegans Movement.

    Science.gov (United States)

    Angstman, Nicholas B; Frank, Hans-Georg; Schmitz, Christoph

    2016-01-01

    As a widely used and studied model organism, Caenorhabditis elegans worms offer the ability to investigate implications of behavioral change. Although, investigation of C. elegans behavioral traits has been shown, analysis is often narrowed down to measurements based off a single point, and thus cannot pick up on subtle behavioral and morphological changes. In the present study videos were captured of four different C. elegans strains grown in liquid cultures and transferred to NGM-agar plates with an E. coli lawn or with no lawn. Using an advanced software, WormLab, the full skeleton and outline of worms were tracked to determine whether the presence of food affects behavioral traits. In all seven investigated parameters, statistically significant differences were found in worm behavior between those moving on NGM-agar plates with an E. coli lawn and NGM-agar plates with no lawn. Furthermore, multiple test groups showed differences in interaction between variables as the parameters that significantly correlated statistically with speed of locomotion varied. In the present study, we demonstrate the validity of a model to analyze C. elegans behavior beyond simple speed of locomotion. The need to account for a nested design while performing statistical analyses in similar studies is also demonstrated. With extended analyses, C. elegans behavioral change can be investigated with greater sensitivity, which could have wide utility in fields such as, but not limited to, toxicology, drug discovery, and RNAi screening.

  4. Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization.

    Science.gov (United States)

    Sun, Siyang; Xiang, Ye; Akahata, Wataru; Holdaway, Heather; Pal, Pankaj; Zhang, Xinzheng; Diamond, Michael S; Nabel, Gary J; Rossmann, Michael G

    2013-04-02

    A 5.3 Å resolution, cryo-electron microscopy (cryoEM) map of Chikungunya virus-like particles (VLPs) has been interpreted using the previously published crystal structure of the Chikungunya E1-E2 glycoprotein heterodimer. The heterodimer structure was divided into domains to obtain a good fit to the cryoEM density. Differences in the T = 4 quasi-equivalent heterodimer components show their adaptation to different environments. The spikes on the icosahedral 3-fold axes and those in general positions are significantly different, possibly representing different phases during initial generation of fusogenic E1 trimers. CryoEM maps of neutralizing Fab fragments complexed with VLPs have been interpreted using the crystal structures of the Fab fragments and the VLP structure. Based on these analyses the CHK-152 antibody was shown to stabilize the viral surface, hindering the exposure of the fusion-loop, likely neutralizing infection by blocking fusion. The CHK-9, m10 and m242 antibodies surround the receptor-attachment site, probably inhibiting infection by blocking cell attachment. DOI:http://dx.doi.org/10.7554/eLife.00435.001.

  5. New genetic and linguistic analyses show ancient human influence on baobab evolution and distribution in Australia.

    Science.gov (United States)

    Rangan, Haripriya; Bell, Karen L; Baum, David A; Fowler, Rachael; McConvell, Patrick; Saunders, Thomas; Spronck, Stef; Kull, Christian A; Murphy, Daniel J

    2015-01-01

    This study investigates the role of human agency in the gene flow and geographical distribution of the Australian baobab, Adansonia gregorii. The genus Adansonia is a charismatic tree endemic to Africa, Madagascar, and northwest Australia that has long been valued by humans for its multiple uses. The distribution of genetic variation in baobabs in Africa has been partially attributed to human-mediated dispersal over millennia, but this relationship has never been investigated for the Australian species. We combined genetic and linguistic data to analyse geographic patterns of gene flow and movement of word-forms for A. gregorii in the Aboriginal languages of northwest Australia. Comprehensive assessment of genetic diversity showed weak geographic structure and high gene flow. Of potential dispersal vectors, humans were identified as most likely to have enabled gene flow across biogeographic barriers in northwest Australia. Genetic-linguistic analysis demonstrated congruence of gene flow patterns and directional movement of Aboriginal loanwords for A. gregorii. These findings, along with previous archaeobotanical evidence from the Late Pleistocene and Holocene, suggest that ancient humans significantly influenced the geographic distribution of Adansonia in northwest Australia.

  6. New genetic and linguistic analyses show ancient human influence on baobab evolution and distribution in Australia.

    Directory of Open Access Journals (Sweden)

    Haripriya Rangan

    Full Text Available This study investigates the role of human agency in the gene flow and geographical distribution of the Australian baobab, Adansonia gregorii. The genus Adansonia is a charismatic tree endemic to Africa, Madagascar, and northwest Australia that has long been valued by humans for its multiple uses. The distribution of genetic variation in baobabs in Africa has been partially attributed to human-mediated dispersal over millennia, but this relationship has never been investigated for the Australian species. We combined genetic and linguistic data to analyse geographic patterns of gene flow and movement of word-forms for A. gregorii in the Aboriginal languages of northwest Australia. Comprehensive assessment of genetic diversity showed weak geographic structure and high gene flow. Of potential dispersal vectors, humans were identified as most likely to have enabled gene flow across biogeographic barriers in northwest Australia. Genetic-linguistic analysis demonstrated congruence of gene flow patterns and directional movement of Aboriginal loanwords for A. gregorii. These findings, along with previous archaeobotanical evidence from the Late Pleistocene and Holocene, suggest that ancient humans significantly influenced the geographic distribution of Adansonia in northwest Australia.

  7. Community males show multiple-perpetrator rape proclivity: development and preliminary validation of an interest scale.

    Science.gov (United States)

    Alleyne, Emma; Gannon, Theresa A; Ó Ciardha, Caoilte; Wood, Jane L

    2014-02-01

    The literature on Multiple Perpetrator Rape (MPR) is scant; however, a significant proportion of sexual offending involves multiple perpetrators. In addition to the need for research with apprehended offenders of MPR, there is also a need to conduct research with members of the general public. Recent advances in the forensic literature have led to the development of self-report proclivity scales. These scales have enabled researchers to conduct evaluative studies sampling from members of the general public who may be perpetrators of sexual offenses and have remained undetected, or at highest risk of engaging in sexual offending. The current study describes the development and preliminary validation of the Multiple-Perpetrator Rape Interest Scale (M-PRIS), a vignette-based measure assessing community males' sexual arousal to MPR, behavioral propensity toward MPR and enjoyment of MPR. The findings show that the M-PRIS is a reliable measure of community males' sexual interest in MPR with high internal reliability and temporal stability. In a sample of university males we found that a large proportion (66%) did not emphatically reject an interest in MPR. We also found that rape-supportive cognitive distortions, antisocial attitudes, and high-risk sexual fantasies were predictors of sexual interest in MPR. We discuss these findings and the implications for further research employing proclivity measures referencing theory development and clinical practice.

  8. Preliminary Findings Show Maternal Hypothyroidism May Contribute to Abnormal Cortical Morphology in Offspring

    Science.gov (United States)

    Lischinsky, Julieta E.; Skocic, Jovanka; Clairman, Hayyah; Rovet, Joanne

    2016-01-01

    In rodents, insufficient thyroid hormone (TH) gestationally has adverse effects on cerebral cortex development. Comparable studies of humans examining how TH insufficiency affects cortical morphology are limited to children with congenital hypothyroidism or offspring of hypothyroxinemic women; effects on cortex of children born to women with clinically diagnosed hypothyroidism are not known. We studied archived MRI scans from 22 children aged 10–12 years born to women treated for preexisting or de novo hypothyroidism in pregnancy (HYPO) and 24 similar age and sex controls from euthyroid women. FreeSurfer Image Analysis Suite software was used to measure cortical thickness (CT) and a vertex-based approach served to compare HYPO versus control groups and Severe versus Mild HYPO subgroups as well as to perform regression analyses examining effects of trimester-specific maternal TSH on CT. Results showed that relative to controls, HYPO had multiple regions of both cortical thinning and thickening, which differed for left and right hemispheres. In HYPO, thinning was confined to medial and mid-lateral regions of each hemisphere and thickening to superior regions (primarily frontal) of the left hemisphere and inferior regions (particularly occipital and temporal) of the right. The Severe HYPO subgroup showed more thinning than Mild in frontal and temporal regions and more thickening in bilateral posterior and frontal regions. Maternal TSH values predicted degree of thinning and thickening within multiple brain regions, with the pattern and direction of correlations differing by trimester. Notably, some correlations remained when cases born to women with severe hypothyroidism were removed from the analyses, suggesting that mild variations of maternal TH may permanently affect offspring cortex. We conclude that maternal hypothyroidism during pregnancy has long-lasting manifestations on the cortical morphology of their offspring with specific effects reflecting both

  9. Preliminary analyses of scenarios for potential human interference for repositories in three salt formations

    Energy Technology Data Exchange (ETDEWEB)

    1985-10-01

    Preliminary analyses of scenarios for human interference with the performance of a radioactive waste repository in a deep salt formation are presented. The following scenarios are analyzed: (1) the U-Tube Connection Scenario involving multiple connections between the repository and the overlying aquifer system; (2) the Single Borehole Intrusion Scenario involving penetration of the repository by an exploratory borehole that simultaneously connects the repository with overlying and underlying aquifers; and (3) the Pressure Release Scenario involving inflow of water to saturate any void space in the repository prior to creep closure with subsequent release under near lithostatic pressures following creep closure. The methodology to evaluate repository performance in these scenarios is described and this methodology is applied to reference systems in three candidate formations: bedded salt in the Palo Duro Basin, Texas; bedded salt in the Paradox Basin, Utah; and the Richton Salt Dome, Mississippi, of the Gulf Coast Salt Dome Basin.

  10. Preliminary Results of Ancillary Safety Analyses Supporting TREAT LEU Conversion Activities

    Energy Technology Data Exchange (ETDEWEB)

    Brunett, A. J. [Argonne National Lab. (ANL), Argonne, IL (United States); Fei, T. [Argonne National Lab. (ANL), Argonne, IL (United States); Strons, P. S. [Argonne National Lab. (ANL), Argonne, IL (United States); Papadias, D. D. [Argonne National Lab. (ANL), Argonne, IL (United States); Hoffman, E. A. [Argonne National Lab. (ANL), Argonne, IL (United States); Kontogeorgakos, D. C. [Argonne National Lab. (ANL), Argonne, IL (United States); Connaway, H. M. [Argonne National Lab. (ANL), Argonne, IL (United States); Wright, A. E. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2015-10-01

    Report (FSAR) [3]. Depending on the availability of historical data derived from HEU TREAT operation, results calculated for the LEU core are compared to measurements obtained from HEU TREAT operation. While all analyses in this report are largely considered complete and have been reviewed for technical content, it is important to note that all topics will be revisited once the LEU design approaches its final stages of maturity. For most safety significant issues, it is expected that the analyses presented here will be bounding, but additional calculations will be performed as necessary to support safety analyses and safety documentation. It should also be noted that these analyses were completed as the LEU design evolved, and therefore utilized different LEU reference designs. Preliminary shielding, neutronic, and thermal hydraulic analyses have been completed and have generally demonstrated that the various LEU core designs will satisfy existing safety limits and standards also satisfied by the existing HEU core. These analyses include the assessment of the dose rate in the hodoscope room, near a loaded fuel transfer cask, above the fuel storage area, and near the HEPA filters. The potential change in the concentration of tramp uranium and change in neutron flux reaching instrumentation has also been assessed. Safety-significant thermal hydraulic items addressed in this report include thermally-induced mechanical distortion of the grid plate, and heating in the radial reflector.

  11. Comparative Analyses of the Lipooligosaccharides from Nontypeable Haemophilus influenzae and Haemophilus haemolyticus Show Differences in Sialic Acid and Phosphorylcholine Modifications.

    Science.gov (United States)

    Post, Deborah M B; Ketterer, Margaret R; Coffin, Jeremy E; Reinders, Lorri M; Munson, Robert S; Bair, Thomas; Murphy, Timothy F; Foster, Eric D; Gibson, Bradford W; Apicella, Michael A

    2016-01-04

    Haemophilus haemolyticus and nontypeable Haemophilus influenzae (NTHi) are closely related upper airway commensal bacteria that are difficult to distinguish phenotypically. NTHi causes upper and lower airway tract infections in individuals with compromised airways, while H. haemolyticus rarely causes such infections. The lipooligosaccharide (LOS) is an outer membrane component of both species and plays a role in NTHi pathogenesis. In this study, comparative analyses of the LOS structures and corresponding biosynthesis genes were performed. Mass spectrometric and immunochemical analyses showed that NTHi LOS contained terminal sialic acid more frequently and to a higher extent than H. haemolyticus LOS did. Genomic analyses of 10 strains demonstrated that H. haemolyticus lacked the sialyltransferase genes lic3A and lic3B (9/10) and siaA (10/10), but all strains contained the sialic acid uptake genes siaP and siaT (10/10). However, isothermal titration calorimetry analyses of SiaP from two H. haemolyticus strains showed a 3.4- to 7.3-fold lower affinity for sialic acid compared to that of NTHi SiaP. Additionally, mass spectrometric and immunochemical analyses showed that the LOS from H. haemolyticus contained phosphorylcholine (ChoP) less frequently than the LOS from NTHi strains. These differences observed in the levels of sialic acid and ChoP incorporation in the LOS structures from H. haemolyticus and NTHi may explain some of the differences in their propensities to cause disease.

  12. Comparative Analyses of the Lipooligosaccharides from Nontypeable Haemophilus influenzae and Haemophilus haemolyticus Show Differences in Sialic Acid and Phosphorylcholine Modifications

    Science.gov (United States)

    Post, Deborah M. B.; Ketterer, Margaret R.; Coffin, Jeremy E.; Reinders, Lorri M.; Munson, Robert S.; Bair, Thomas; Murphy, Timothy F.; Foster, Eric D.; Gibson, Bradford W.

    2016-01-01

    Haemophilus haemolyticus and nontypeable Haemophilus influenzae (NTHi) are closely related upper airway commensal bacteria that are difficult to distinguish phenotypically. NTHi causes upper and lower airway tract infections in individuals with compromised airways, while H. haemolyticus rarely causes such infections. The lipooligosaccharide (LOS) is an outer membrane component of both species and plays a role in NTHi pathogenesis. In this study, comparative analyses of the LOS structures and corresponding biosynthesis genes were performed. Mass spectrometric and immunochemical analyses showed that NTHi LOS contained terminal sialic acid more frequently and to a higher extent than H. haemolyticus LOS did. Genomic analyses of 10 strains demonstrated that H. haemolyticus lacked the sialyltransferase genes lic3A and lic3B (9/10) and siaA (10/10), but all strains contained the sialic acid uptake genes siaP and siaT (10/10). However, isothermal titration calorimetry analyses of SiaP from two H. haemolyticus strains showed a 3.4- to 7.3-fold lower affinity for sialic acid compared to that of NTHi SiaP. Additionally, mass spectrometric and immunochemical analyses showed that the LOS from H. haemolyticus contained phosphorylcholine (ChoP) less frequently than the LOS from NTHi strains. These differences observed in the levels of sialic acid and ChoP incorporation in the LOS structures from H. haemolyticus and NTHi may explain some of the differences in their propensities to cause disease. PMID:26729761

  13. Boxing and mixed martial arts: preliminary traumatic neuromechanical injury risk analyses from laboratory impact dosage data.

    Science.gov (United States)

    Bartsch, Adam J; Benzel, Edward C; Miele, Vincent J; Morr, Douglas R; Prakash, Vikas

    2012-05-01

    In spite of ample literature pointing to rotational and combined impact dosage being key contributors to head and neck injury, boxing and mixed martial arts (MMA) padding is still designed to primarily reduce cranium linear acceleration. The objects of this study were to quantify preliminary linear and rotational head impact dosage for selected boxing and MMA padding in response to hook punches; compute theoretical skull, brain, and neck injury risk metrics; and statistically compare the protective effect of various glove and head padding conditions. An instrumented Hybrid III 50th percentile anthropomorphic test device (ATD) was struck in 54 pendulum impacts replicating hook punches at low (27-29 J) and high (54-58 J) energy. Five padding combinations were examined: unpadded (control), MMA glove-unpadded head, boxing glove-unpadded head, unpadded pendulum-boxing headgear, and boxing glove-boxing headgear. A total of 17 injury risk parameters were measured or calculated. All padding conditions reduced linear impact dosage. Other parameters significantly decreased, significantly increased, or were unaffected depending on padding condition. Of real-world conditions (MMA glove-bare head, boxing glove-bare head, and boxing glove-headgear), the boxing glove-headgear condition showed the most meaningful reduction in most of the parameters. In equivalent impacts, the MMA glove-bare head condition induced higher rotational dosage than the boxing glove-bare head condition. Finite element analysis indicated a risk of brain strain injury in spite of significant reduction of linear impact dosage. In the replicated hook punch impacts, all padding conditions reduced linear but not rotational impact dosage. Head and neck dosage theoretically accumulates fastest in MMA and boxing bouts without use of protective headgear. The boxing glove-headgear condition provided the best overall reduction in impact dosage. More work is needed to develop improved protective padding to minimize

  14. Electrocochleographic recording in Asian adults: Preliminary normative data and demographic analyses

    Directory of Open Access Journals (Sweden)

    Mohd Normani Zakaria

    2017-03-01

    Conclusion: The present study provides preliminary normative data for ET-ECochG among Asian adults. The ECochG components do not appear to be influenced by either ethnicity or gender. The derived normative data can be used for clinical applications and as the reference for future studies involving Asian population.

  15. Community-level physiological profiling analyses show potential to identify the copiotrophic bacteria present in soil environments

    Science.gov (United States)

    Lladó, Salvador; Baldrian, Petr

    2017-01-01

    Community-level physiological profiling (CLPP) analyses from very diverse environments are frequently used with the aim of characterizing the metabolic versatility of whole environmental bacterial communities. While the limitations of the methodology for the characterization of whole communities are well known, we propose that CLPP combined with high-throughput sequencing and qPCR can be utilized to identify the copiotrophic, fast-growing fraction of the bacterial community of soil environments, where oligotrophic taxa are usually dominant. In the present work we have used this approach to analyze samples of litter and soil from a coniferous forest in the Czech Republic using BIOLOG GN2 plates. Monosaccharides and amino acids were utilized significantly faster than other C substrates, such as organic acids, in both litter and soil samples. Bacterial biodiversity in CLPP wells was significantly lower than in the original community, independently of the carbon source. Bacterial communities became highly enriched in taxa that typically showed low abundance in the original soil, belonging mostly to the Gammaproteobacteria and the genus Pseudomonas, indicating that the copiotrophic strains, favoured by the high nutrient content, are rare in forest litter and soil. In contrast, taxa abundant in the original samples were rarely found to grow at sufficient rates under the CLPP conditions. Our results show that CLPP is useful to detect copiotrophic bacteria from the soil environments and that bacterial growth is substrate specific. PMID:28170446

  16. Preliminary results and analyses of using IGS GPS data to determine global ionospheric TEC

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Using the spherical harmonic (SH) function model and the dual frequency GPS data of 139 International GPS Service (IGS) stations for July 15 of 2000, the global ionospheric total electron content (TEC) is calculated and the basic method is investigated. Here, preliminary results are reported and the problems and difficulties to be solved for using GPS data to determine the global ionospheric TEC are discussed.

  17. Neutronic analyses of the preliminary design of a DCLL blanket for the EUROfusion DEMO power plant

    Energy Technology Data Exchange (ETDEWEB)

    Palermo, Iole, E-mail: iole.palermo@ciemat.es; Fernández, Iván; Rapisarda, David; Ibarra, Angel

    2016-11-01

    Highlights: • We perform neutronic calculations for the preliminary DCLL Blanket design. • We study the tritium breeding capability of the reactor. • We determine the nuclear heating in the main components. • We verify if the shielding of the TF coil is maintained. - Abstract: In the frame of the newly established EUROfusion WPBB Project for the period 2014–2018, four breeding blanket options are being investigated to be used in the fusion power demonstration plant DEMO. CIEMAT is leading the development of the conceptual design of the Dual Coolant Lithium Lead, DCLL, breeding blanket. The primary role of the blanket is of energy extraction, tritium production, and radiation shielding. With this aim the DCLL uses LiPb as primary coolant, tritium breeder and neutron multiplier and Eurofer as structural material. Focusing on the achievement of the fundamental neutronic responses a preliminary blanket model has been designed. Thus detailed 3D neutronic models of the whole blanket modules have been generated, arranged in a specific DCLL segmentation and integrated in the generic DEMO model. The initial design has been studied to demonstrate its viability. Thus, the neutronic behaviour of the blanket and of the shield systems in terms of tritium breeding capabilities, power generation and shielding efficiency has been assessed in this paper. The results demonstrate that the primary nuclear performances are already satisfactory at this preliminary stage of the design, having obtained the tritium self-sufficiency and an adequate shielding.

  18. Alcohol-Dependent Subjects Show Different Personality Traits Compared With Subjects With Multiple Substance Dependence: Preliminary Data.

    Science.gov (United States)

    Koller, Gabi; Preuss, Ullrich; Lü, Osman; Soyka, Michael; Pogarell, Oliver

    2015-01-01

    We compared personality traits of 27 persons with multiple substance dependence with personality data of 52 alcohol-dependent persons regarding their personality traits and disorders (obtained by using SCID-II, TCI and NEO FFI). Both patient groups were free of any other mental disorder. In SKD-II, we found significant differences in the male group in dependent and scizotypic personality disorder. There were no significant differences in the female group, but sample was very small. We also found significant differences between alcohol-dependent and multiple substance-dependent persons in extraversion and novelty seeking. We detected significant differences in personality disorders evaluated by SCID-II. Temperament and character items—as evaluated by NEO FFI and TCI—showed also significant differences in personality traits. Given the limited number of subjects, the data should be regarded as preliminary until replicated in a larger sample. Nevertheless, the findings may be of clinical relevance with respect to prognosis or individualized treatment. These findings should be treated with caution until replicated.

  19. Multitemporal satellite data analyses for archaeological mark detection: preliminary results in Italy and Argentina

    Science.gov (United States)

    Lasaponara, Rosa; Masini, Nicola

    2014-05-01

    within Basilicata and Puglia Region, southern Patagonia and Payunia-Campo Volcanicos Liancanelo e PayunMatru respectively, in Italy and Argentina. We focused our attention on diverse surfaces and soil types in different periods of the year in order to assess the capabilities of both optical and radar data to detect archaeological marks in different ecosystems and seasons. We investigated not only crop culture during the "favourable vegetative period" to enhance the presence of subsurface remains but also the "spectral response" of spontaneous, sparse herbaceous covers during periods considered and expected to be less favourable (as for example summer and winter) for this type of investigation. The main interesting results were the capability of radar (cosmoskymed) and multispectral optical data satellite data (Pleiades, Quickbird, Geoeye) to highlight the presence of structures below the surface even (i) in during period of years generally considered not "suitable for crop mark investigations" and even (ii) in areas only covered by sparse, spontaneous herbaceous plants in several test sites investigate din both Argentine and Italian areas of interest. Preliminary results conducted in both Italian and Argentina sites pointed out that Earth Observation (EO) technology can be successfully used for extracting useful information on traces the past human activities still fossilized in the modern landscape in different ecosystems and seasons. Moreover the multitemporal analyses of satellite data can fruitfully applied to: (i) improve knowledge, (ii) support monitoring of natural and cultural site, (iii) assess natural and man-made risks including emerging threats to the heritage sites. References Lasaponara R, N Masini 2009 Full-waveform Airborne Laser Scanning for the detection of medieval archaeological microtopographic relief Journal of Cultural Heritage 10, e78-e82 Ciminale M, D Gallo, R Lasaponara, N Masini 2009 A multiscale approach for reconstructing archaeological

  20. Preliminary study showing safety/efficacy of nanoss bioactive versus vitoss as bone graft expanders for lumbar noninstrumented fusions

    Directory of Open Access Journals (Sweden)

    Nancy E Epstein

    2015-01-01

    Conclusion: In this preliminary study of patients undergoing multilevel lumbar lamienctomies with posterolateral noninstrumented fusions, results were nearly comparable utilizing Vitoss or NanOss as bone graft expanders. Although the number of NanOss patients was substantially lower, the comparable efficacy and absence of postoperative complications for noninstrumented fusions is promising.

  1. Preliminary correlations of feature strength in spark-induced breakdown spectroscopy of bioaerosols with concentrations measured in laboratory analyses

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, Morgan S.; Bauer, Amy J. Ray

    2010-05-01

    We present preliminary results that show good correlation between elemental compositions of three bioaerosol samples, as measured in the laboratory by combustion analysis and with proton-induced x-ray emission and spark-induced breakdown spectroscopy signals integrated over the entire emission time profiles. Atomic (Ca, Al, Fe, and Si) and molecular features (CN, N2{sup +}, and OH) were observed compared to the laboratory data.

  2. Preliminary Thermal Hydraulic Analyses of the Conceptual Core Models with Tubular Type Fuel Assemblies

    Energy Technology Data Exchange (ETDEWEB)

    Chae, Hee Taek; Park, Jong Hark; Park, Cheol

    2006-11-15

    A new research reactor (AHR, Advanced HANARO Reactor) based on the HANARO has being conceptually developed for the future needs of research reactors. A tubular type fuel was considered as one of the fuel options of the AHR. A tubular type fuel assembly has several curved fuel plates arranged with a constant small gap to build up cooling channels, which is very similar to an annulus pipe with many layers. This report presents the preliminary analysis of thermal hydraulic characteristics and safety margins for three conceptual core models using tubular fuel assemblies. Four design criteria, which are the fuel temperature, ONB (Onset of Nucleate Boiling) margin, minimum DNBR (Departure from Nucleate Boiling Ratio) and OFIR (Onset of Flow Instability Ratio), were investigated along with various core flow velocities in the normal operating conditions. And the primary coolant flow rate based a conceptual core model was suggested as a design information for the process design of the primary cooling system. The computational fluid dynamics analysis was also carried out to evaluate the coolant velocity distributions between tubular channels and the pressure drop characteristics of the tubular fuel assembly.

  3. Analysing spatial trends in referral patterns to cancer genetics services: a preliminary investigation of regional variations in Wales.

    Science.gov (United States)

    McDonald, Kevin; Higgs, Gary; Iredale, Rachel; Tempest, Vanessa; Gray, Jonathon

    2004-11-01

    This paper discusses spatial trends in referral patterns to a cancer genetics service. It presents a literature review outlining the paucity of existing research, a preliminary analysis at the Unitary Authority level in Wales and advances a programme of further research to be conducted at a more detailed spatial level. The preliminary analysis shows a weak negative relationship between referral rates from primary care and social deprivation by Unitary Authority (Spearman rank correlation coefficient, sigma = -0.38). There is also a weak positive relationship between average settlement size and referral rates (sigma = +0.28), which taken together may indicate that primary care practices in affluent urban areas are more likely to refer than those in poorer rural areas. Future research will be conducted at a finer spatial scale, and will take into account characteristics of primary care practices and the patients being referred, amongst other variables.

  4. Improved efficiency thanks to modulated power - Exergy analyses show the way; Une meilleure efficacite grace au reglage continu de la puissance. Des analyses exergetiques montrent le chemin

    Energy Technology Data Exchange (ETDEWEB)

    Wellstein, J.

    2009-07-01

    This article summarizes the results of two research projects conducted at the University of Applied Sciences in Lucerne, Switzerland and supported by the Swiss Federal Office of Energy. Following the rapid development of the heat pump market for space heating in the past decades in Switzerland, the improvement of the heat pump coefficient of performance COP becomes a highly relevant issue. The problem is especially acute for air/water heat pumps, due to the fact that the COP significantly decreases when the outdoor air temperature decreases. However, laboratory measurements show that the COP could be much higher at intermediate heat load if less irreversibility in the thermodynamic cycle would occur. The Lucerne researchers have identified the exergy loss origins. Continuous heat power modulation instead of ON/OFF control of the heat pump compressor is one way for COP improvement. Another need for optimization was found in the construction of the finned lamellar heat exchanger used as evaporator. This can significantly reduce fin icing and, consequently, the power consumption during deicing.

  5. Perceived conflict in the couple and chronic illness management: Preliminary analyses from the Quebec Health Survey

    Directory of Open Access Journals (Sweden)

    Hudon Catherine

    2006-10-01

    females with more than one chronic condition were more likely to have a negative perception of their general health and mental health. Conclusion The study provides a useful preliminary measure of the importance of living arrangements and the quality of the couple relationship in chronic illness management broadly conceived as a measure of the patient's efforts at self-care and an illness status indicator. Results of this study prod us to examine more closely, within longitudinal designs, the influence of living arrangements and the presence of conflict in the couple on chronic illness management as well as the modifying effect of gender on these associations.

  6. Preliminary Accident Analyses for Conversion of the Massachusetts Institute of Technology Reactor (MITR) from Highly Enriched to Low Enriched Uranium

    Energy Technology Data Exchange (ETDEWEB)

    Dunn, Floyd E. [Argonne National Lab. (ANL), Argonne, IL (United States); Olson, Arne P. [Argonne National Lab. (ANL), Argonne, IL (United States); Wilson, Erik H. [Argonne National Lab. (ANL), Argonne, IL (United States); Sun, Kaichao S. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Newton, Jr., Thomas H. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Hu, Lin-wen [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

    2013-09-30

    The Massachusetts Institute of Technology Reactor (MITR-II) is a research reactor in Cambridge, Massachusetts designed primarily for experiments using neutron beam and in-core irradiation facilities. It delivers a neutron flux comparable to current LWR power reactors in a compact 6 MW core using Highly Enriched Uranium (HEU) fuel. In the framework of its non-proliferation policies, the international community presently aims to minimize the amount of nuclear material available that could be used for nuclear weapons. In this geopolitical context most research and test reactors, both domestic and international, have started a program of conversion to the use of LEU fuel. A new type of LEU fuel based on an alloy of uranium and molybdenum (U-Mo) is expected to allow the conversion of U.S. domestic high performance reactors like MITR. This report presents the preliminary accident analyses for MITR cores fueled with LEU monolithic U-Mo alloy fuel with 10 wt% Mo. Preliminary results demonstrate adequate performance, including thermal margin to expected safety limits, for the LEU accident scenarios analyzed.

  7. Geoarchaeology of Ancient Karnak's harbour (Upper Egypt) : preliminary results derived from sedimentological analyses

    Science.gov (United States)

    Ghilardi, M.

    2009-04-01

    This paper aims to detail the first results of a geomorphological study, led in the western part of the Karnak Temple, Upper Egypt. The geoarchaeological approach privileged here helps to better understand the Nile River dynamics in the neighbourhood of the ancient harbour and of the jetty identified by archaeologists. Based on the study of six stratigraphical profiles, realized by the Egyptian Supreme Council of Antiquities and sixteen manual auger boreholes (up to a maximum depth of 3.50m) drilled in November 2008, the results clearly indicate the continuous presence of Nile River westward of the first Pylon. The boreholes were drilled westward and eastward of the ancient fluvial harbour. Fluvial dynamics characterized by flood events, sandy accretions and large Nile silts depositions are presented and discussed here for later palaeoenvironmental reconstruction. The accurate levelling of the different profiles and boreholes, with the help a topographic survey, allow us to get long sedimentological sequences and to correlate the different sedimentary units. Perspectives of research are introduced with the possibility to realize sedimentological analyses which include the grain-size distribution (sieving method employed) and a magnetic susceptibility study of the different sediments described. Finally, in order to obtain chronostratigraphic sequences, it is also proposed to perform radiocarbon dating on charcoal samples.

  8. Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability.

    Science.gov (United States)

    Mlecnik, Bernhard; Bindea, Gabriela; Angell, Helen K; Maby, Pauline; Angelova, Mihaela; Tougeron, David; Church, Sarah E; Lafontaine, Lucie; Fischer, Maria; Fredriksen, Tessa; Sasso, Maristella; Bilocq, Amélie M; Kirilovsky, Amos; Obenauf, Anna C; Hamieh, Mohamad; Berger, Anne; Bruneval, Patrick; Tuech, Jean-Jacques; Sabourin, Jean-Christophe; Le Pessot, Florence; Mauillon, Jacques; Rafii, Arash; Laurent-Puig, Pierre; Speicher, Michael R; Trajanoski, Zlatko; Michel, Pierre; Sesboüe, Richard; Frebourg, Thierry; Pagès, Franck; Valge-Archer, Viia; Latouche, Jean-Baptiste; Galon, Jérôme

    2016-03-15

    Microsatellite instability in colorectal cancer predicts favorable outcomes. However, the mechanistic relationship between microsatellite instability, tumor-infiltrating immune cells, Immunoscore, and their impact on patient survival remains to be elucidated. We found significant differences in mutational patterns, chromosomal instability, and gene expression that correlated with patient microsatellite instability status. A prominent immune gene expression was observed in microsatellite-instable (MSI) tumors, as well as in a subgroup of microsatellite-stable (MSS) tumors. MSI tumors had increased frameshift mutations, showed genetic evidence of immunoediting, had higher densities of Th1, effector-memory T cells, in situ proliferating T cells, and inhibitory PD1-PDL1 cells, had high Immunoscores, and were infiltrated with mutation-specific cytotoxic T cells. Multivariate analysis revealed that Immunoscore was superior to microsatellite instability in predicting patients' disease-specific recurrence and survival. These findings indicate that assessment of the immune status via Immunoscore provides a potent indicator of tumor recurrence beyond microsatellite-instability staging that could be an important guide for immunotherapy strategies.

  9. Elapid Snake Venom Analyses Show the Specificity of the Peptide Composition at the Level of Genera Naja and Notechis

    Directory of Open Access Journals (Sweden)

    Aisha Munawar

    2014-02-01

    Full Text Available Elapid snake venom is a highly valuable, but till now mainly unexplored, source of pharmacologically important peptides. We analyzed the peptide fractions with molecular masses up to 10 kDa of two elapid snake venoms—that of the African cobra, N. m. mossambica (genus Naja, and the Peninsula tiger snake, N. scutatus, from Kangaroo Island (genus Notechis. A combination of chromatographic methods was used to isolate the peptides, which were characterized by combining complimentary mass spectrometric techniques. Comparative analysis of the peptide compositions of two venoms showed specificity at the genus level. Three-finger (3-F cytotoxins, bradykinin-potentiating peptides (BPPs and a bradykinin inhibitor were isolated from the Naja venom. 3-F neurotoxins, Kunitz/basic pancreatic trypsin inhibitor (BPTI-type inhibitors and a natriuretic peptide were identified in the N. venom. The inhibiting activity of the peptides was confirmed in vitro with a selected array of proteases. Cytotoxin 1 (P01467 from the Naja venom might be involved in the disturbance of cellular processes by inhibiting the cell 20S-proteasome. A high degree of similarity between BPPs from elapid and viperid snake venoms was observed, suggesting that these molecules play a key role in snake venoms and also indicating that these peptides were recruited into the snake venom prior to the evolutionary divergence of the snakes.

  10. Economic and Risk Analyses for SMEs Internationalization Projects. A Preliminary Insight on the Rationale of Business Consulting Firms

    Directory of Open Access Journals (Sweden)

    Elena - Madalina VĂTĂMĂNESCU

    2014-06-01

    Full Text Available The present study is meant to be a first step towards the investigation of two current issues: the organization’s demand for highly professional services and the business consulting firms’ response as a challenge for the ethic imperatives. The main question raised is whether the national business consulting firms are liable to provide the economic and risk analyses required by the ambitious internationalization projects of small and medium enterprises (SMEs, and if not, what should be the firms’ ethical approach. In this respect, preliminary conclusions were made after testing the deliverables of several business consulting firms which were contracted to elaborate intricate economic and risk analyses of an internationalization project developed by a medium enterprise. The proven level of expertise of the contracted firms did not confirm their claims and assurances that they were fit for the job. This is why the rationale of today’s business consulting firms should be taken into account for further consideration while the exigency for increased savvy should become a priority.

  11. Preliminary study to characterize plastic polymers using elemental analyser/isotope ratio mass spectrometry (EA/IRMS).

    Science.gov (United States)

    Berto, Daniela; Rampazzo, Federico; Gion, Claudia; Noventa, Seta; Ronchi, Francesca; Traldi, Umberto; Giorgi, Giordano; Cicero, Anna Maria; Giovanardi, Otello

    2017-06-01

    Plastic waste is a growing global environmental problem, particularly in the marine ecosystems, in consideration of its persistence. The monitoring of the plastic waste has become a global issue, as reported by several surveillance guidelines proposed by Regional Sea Conventions (OSPAR, UNEP) and appointed by the EU Marine Strategy Framework Directive. Policy responses to plastic waste vary at many levels, ranging from beach clean-up to bans on the commercialization of plastic bags and to Regional Plans for waste management and recycling. Moreover, in recent years, the production of plant-derived biodegradable plastic polymers has assumed increasing importance. This study reports the first preliminary characterization of carbon stable isotopes (δ(13)C) of different plastic polymers (petroleum- and plant-derived) in order to increase the dataset of isotopic values as a tool for further investigation in different fields of polymers research as well as in the marine environment surveillance. The δ(13)C values determined in different packaging for food uses reflect the plant origin of "BIO" materials, whereas the recycled plastic materials displayed a δ(13)C signatures between plant- and petroleum-derived polymers source. In a preliminary estimation, the different colours of plastic did not affect the variability of δ(13)C values, whereas the abiotic and biotic degradation processes that occurred in the plastic materials collected on beaches and in seawater, showed less negative δ(13)C values. A preliminary experimental field test confirmed these results. The advantages offered by isotope ratio mass spectrometry with respect to other analytical methods used to characterize the composition of plastic polymers are: high sensitivity, small amount of material required, rapidity of analysis, low cost and no limitation in black/dark samples compared with spectroscopic analysis.

  12. Nomothetic outcome assessment in counseling and psychotherapy: Development and preliminary psychometric analyses of the Depression/Anxiety Negative Affect Scale

    Directory of Open Access Journals (Sweden)

    Scott T. Meier

    2012-12-01

    Full Text Available Negative affect (NA plays a significant role in the initiation, persistence, and response to psychotherapy of many client problems (Moses & Barlow, 2006. This report describes the development of a brief NA measure, the Depression/Anxiety Negative Affect (DANA scale, and preliminary analyses of its psychometric properties. An initial pool of DANA items was selected on the basis of a review of relevant literature about emotion science and counseling outcomes, related tests, and feedback from psychotherapists as part of a pilot test. The DANA was evaluated in two representative clinical samples where psychotherapists produced a total of 363 session ratings with 81 clients. DANA scores evidenced adequate internal consistency, evidence of convergent and discriminant validity, and sensitivity to change over the course of psychotherapy. Effect sizes (ES of DANA scores consistently equaled or exceeded the average ES of .68 found for scales assessing the outcomes of counseling and psychotherapy in meta-analytic studies (Smith & Glass, 1977. ESs greater than 1 were found on DANA variables for clients whose therapists rated them as experiencing, rather than avoiding, NA.

  13. Theoretical analyses and numerical simulations of the torsional mode for two acoustic viscometers with preliminary experimental tests.

    Science.gov (United States)

    Ai, Yuhui; Lange, Rebecca A

    2008-03-01

    A rigorous analysis of the torsional modes in both a cylindrical wave guide and the associated static viscous fluid field has been conducted from the solid and the fluid wave equations and the coupled boundary conditions. As a result, two acoustic viscometer models, along with four independent equations connecting the density and the viscosity of the fluid with the attenuation and the phase velocity of the torsional wave in the wave guide, have been developed. The analysis shows that the product of the viscosity and the density of the fluid can be measured from the end reflection coefficient of the torsional wave in the wave guide and that both the viscosity and the density can be determined simultaneously from either the phase velocity or the attenuation of the torsional wave in a single cylindrical wave guide. For the simultaneous measurements of the viscosity and the density, the independent equations have to be solved numerically, for example, using Matlab (The MathWorks, Natick, MA), given either the attenuation or the phase velocity in the wave guide that is surrounded by the fluid. To demonstrate the technical feasibility, numerical simulations have been conducted to discern viscosity, phase velocity, and density, all versus attenuation, at different frequencies, and with variable dimension of a molybdenum rod, so that both the advantages and the disadvantages of the simultaneous measurements can be explored. In the end, to test the two models, preliminary experiments on two viscous standards were conducted at 23 degrees C, and good agreements have been achieved between the viscosities measured from both models and for both standards.

  14. Maps and tables showing data and analyses of semiquantitative emmission spectrometry and atomic-absorption spectrophotometry of rock samples, Ugashik, Bristol Bay, and part of Karluk quadrangles, Alaska

    Science.gov (United States)

    Wilson, Frederic H.; O'Leary, R. M.

    1986-01-01

    The accompanying maps and tables show analytical data and data analyses from rock samples collected in conjunction with geologic mapping in the Ugashik, Bristol Bay and western Karluck quadrangles from 1979 through 1981. This work was conducted under the auspices of the Alaska Mineral Resource Assessment Program (AMRAP). A total of 337 samples were collected for analysis, primarily in areas of surficial alteration. The sample locations are shown on sheet 1: they are concentrated along the Pacific Ocean side of the area because the Bristol Bay lowlands part of the map is predominantly unconsolidated Quaternary deposits. Sample collection was by the following people, with their respective two letter identifying code shown in parentheses: W.H. Allaway (AY), J.E. Case (CE), D.P. Cox (CX), R.L. Detterman, (DT), T.G. Theodore (MK), F.H. Wilson (WS), and M.E. Yount (YB).

  15. Preliminary study of microscale zircon oxygen isotopes for Dabie-Sulu metamorphic rocks: Ion probe in situ analyses

    Institute of Scientific and Technical Information of China (English)

    CHEN Daogong; Deloule Etienne; CHENG Hao; XIA Qunke; WU Yuanbao

    2003-01-01

    151 in situ analyses of oxygen isotopes were carried out by ion micro-probe for zircons from 8 localities of HP-UHP metamorphic rocks including eclogites in the Dabie-Sulu terrane. The results show significant heterogeneity inδ18O values, with variation in different rocks from -8.5‰ to +9.7‰ and within one sample from 2‰ to 12‰. No measurable difference inδ18O was observed between protolith magmatic (detrital) zircons and metamorphic recrystallized zircons within analytical uncertainties from the ion micro-probe measurements. This indicates that the metamorphic zircons have inherited the oxygen isotopic compositions of protolith zircons despite the HP to UHP metamorphism. According to their protolith ages from zircon U-Pb in situ dating by the same ion micro-probe, two groups of oxygen isotope composition are recognized, with one having δ18O values of 6‰-7‰ for old protolith of 1.9-2.5 Ga ages and the other 0‰-2‰ for young protolith of 0.7-0.8 Ga ages. The latter anomalously lowδ18O values of zircons indicate that the magma has had the obvious involvement of meteoric water when forming the young protolith of high-grade metamorphic rocks. This may be correlated with the snowball Earth event occurring in South China and the world elsewhere during the Neoproterozoic.

  16. MRI analyses show that kinesio taping affects much more than just the targeted superficial tissues and causes heterogeneous deformations within the whole limb.

    Science.gov (United States)

    Pamuk, Uluç; Yucesoy, Can A

    2015-12-16

    Kinesio taping (KT) is widely used in the treatment of sports injuries and various neuro-musculoskeletal disorders. However, it is considered as selectively effective on targeted tissues and its mechanical effects have not been quantified objectively. Ascribed to continuity of muscular and connective tissues, mechanical loading imposed can have widespread heterogeneous effects. The aim was to characterize the mechanical effects of KT objectively and to test the hypotheses that KT causes acutely, local deformations not necessarily (I) in agreement with tape adhering direction and (II) limited to the directly targeted tissues. High-resolution 3D magnetic resonance image sets were acquired in healthy human subjects (n=5) prior to and acutely after KT application over the skin along m. tibialis anterior (TA). Hip, knee and ankle angles were kept constant. Demons image registration algorithm was used to calculate local tissue deformations within the lower leg, in vivo. Mean peak tissue strains were significantly higher than strain artifacts. Only KT-to-TA region in part shows local deformations in agreement with tape adhering direction whereas, superficial skin, the rest of KT-to-TA and TA regions show deformations (up to 51.5% length change) in other directions. Non-targeted tissues also show sizable heterogeneous deformations, but in smaller amplitudes. Inter-subject variability is notable. Magnetic resonance imaging analyses allow for a detailed assessment of local tissue deformation occurring acutely after KT application. The findings confirm our hypotheses and characterize how KT affects the underlying tissues, both immediately targeted and distant. This allows revealing mechanisms that can affect clinical outcomes of KT objectively.

  17. Preliminary analyses of the deep geoenvironmental characteristics for the deep borehole disposal of high-level radioactive waste in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jong Youl; Lee, Min Soo; Choi, Heui Joo; Kim, Geon Young; Kim, Kyung Su [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-06-15

    Spent fuels from nuclear power plants, as well as high-level radioactive waste from the recycling of spent fuels, should be safely isolated from human environment for an extremely long time. Recently, meaningful studies on the development of deep borehole radioactive waste disposal system in 3-5 km depth have been carried out in USA and some countries in Europe, due to great advance in deep borehole drilling technology. In this paper, domestic deep geoenvironmental characteristics are preliminarily investigated to analyze the applicability of deep borehole disposal technology in Korea. To do this, state-of-the art technologies in USA and some countries in Europe are reviewed, and geological and geothermal data from the deep boreholes for geothermal usage are analyzed. Based on the results on the crystalline rock depth, the geothermal gradient and the spent fuel types generated in Korea, a preliminary deep borehole concept including disposal canister and sealing system, is suggested.

  18. Whole Proteome Analyses on Ruminiclostridium cellulolyticum Show a Modulation of the Cellulolysis Machinery in Response to Cellulosic Materials with Subtle Differences in Chemical and Structural Properties

    Science.gov (United States)

    Badalato, Nelly; Guillot, Alain; Sabarly, Victor; Dubois, Marc; Pourette, Nina; Pontoire, Bruno; Robert, Paul; Bridier, Arnaud; Monnet, Véronique; Sousa, Diana Z.; Durand, Sylvie; Mazéas, Laurent; Buléon, Alain; Bouchez, Théodore; Mortha, Gérard

    2017-01-01

    Lignocellulosic materials from municipal solid waste emerge as attractive resources for anaerobic digestion biorefinery. To increase the knowledge required for establishing efficient bioprocesses, dynamics of batch fermentation by the cellulolytic bacterium Ruminiclostridium cellulolyticum were compared using three cellulosic materials, paper handkerchief, cotton discs and Whatman filter paper. Fermentation of paper handkerchief occurred the fastest and resulted in a specific metabolic profile: it resulted in the lowest acetate-to-lactate and acetate-to-ethanol ratios. By shotgun proteomic analyses of paper handkerchief and Whatman paper incubations, 151 proteins with significantly different levels were detected, including 20 of the 65 cellulosomal components, 8 non-cellulosomal CAZymes and 44 distinct extracytoplasmic proteins. Consistent with the specific metabolic profile observed, many enzymes from the central carbon catabolic pathways had higher levels in paper handkerchief incubations. Among the quantified CAZymes and cellulosomal components, 10 endoglucanases mainly from the GH9 families and 7 other cellulosomal subunits had lower levels in paper handkerchief incubations. An in-depth characterization of the materials used showed that the lower levels of endoglucanases in paper handkerchief incubations could hypothetically result from its lower crystallinity index (50%) and degree of polymerization (970). By contrast, the higher hemicellulose rate in paper handkerchief (13.87%) did not result in the enhanced expression of enzyme with xylanase as primary activity, including enzymes from the “xyl-doc” cluster. It suggests the absence, in this material, of molecular structures that specifically lead to xylanase induction. The integrated approach developed in this work shows that subtle differences among cellulosic materials regarding chemical and structural characteristics have significant effects on expressed bacterial functions, in particular the

  19. Neuropsychological impairment as a consequence of football (soccer) play and football heading: preliminary analyses and report on university footballers.

    Science.gov (United States)

    Rutherford, A; Stephens, R; Potter, D; Fernie, G

    2005-04-01

    Previous research has claimed neuropsychological impairment occurs as a result of professional and amateur football play, and, specifically, football heading. However, much of this research exhibits substantial methodological problems. By investigating less committed amateur level footballers, the current study sought to gain some insight into the developmental history of any neuropsychological consequences of football play. University football, rugby and noncontact sports players were compared on a range of biographical and neuropsychological test variables. While playing their chosen sports, rugby players sustained many more head injuries than footballers and noncontact sportsmen, but footballers did not sustain significantly more head injuries than noncontact sportsmen. The number of head injuries sustained predicted Trails B and TAP Divided Attention latencies in a positive fashion. After controlling for the number of head injuries sustained, sport group effects were detected with TAP Divided Attention accuracy scores, with footballers exhibiting poorest performance. After controlling for the number of head injuries sustained, the total amount of heading done by footballers predicted the number of Wisconsin Card Sorting category shifts in a negative fashion. Nevertheless, over interpretation of all of these results should be resisted because of the exploratory nature of the analyses and the possibility that the sport groups may differ in ways other than just the nature of their sports activities.

  20. Tables showing analyses of semiquantitative spectrometry and atomic-absorption spectrophotometry of rock samples collected in the Ugashik, Bristol Bay, and western part of the Karluk quadrangles, Alaska

    Science.gov (United States)

    Wilson, Frederic H.; O'Leary, Richard M.

    1987-01-01

    The accompanying tables list chemical analyses of 337 rock samples that were collected in 1979, 1980, and 1981 in conjunction with geologic mapping in the Ugashik, Bristol Bay, and part of Karluk quadrangles. This work was conducted under the auspices of the Alaska Mineral Resource Assessment Program (AMRAP). This report is to accompany Wilson and O'Leary (1986) which inadvertently is missing most of the data tables listed here. Together the two reports contain the complete data from all samples collected for the Ugashik AMRAP.

  1. Preliminary performance assessment for the Waste Isolation Pilot Plant, December 1992. Volume 5, Uncertainty and sensitivity analyses of gas and brine migration for undisturbed performance

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-01

    Before disposing of transuranic radioactive waste in the Waste Isolation Pilot Plant (WIPP), the United States Department of Energy (DOE) must evaluate compliance with applicable long-term regulations of the United States Environmental Protection Agency (EPA). Sandia National Laboratories is conducting iterative performance assessments (PAs) of the WIPP for the DOE to provide interim guidance while preparing for a final compliance evaluation. This volume of the 1992 PA contains results of uncertainty and sensitivity analyses with respect to migration of gas and brine from the undisturbed repository. Additional information about the 1992 PA is provided in other volumes. Volume 1 contains an overview of WIPP PA and results of a preliminary comparison with 40 CFR 191, Subpart B. Volume 2 describes the technical basis for the performance assessment, including descriptions of the linked computational models used in the Monte Carlo analyses. Volume 3 contains the reference data base and values for input parameters used in consequence and probability modeling. Volume 4 contains uncertainty and sensitivity analyses with respect to the EPA`s Environmental Standards for the Management and Disposal of Spent Nuclear Fuel, High-Level and Transuranic Radioactive Wastes (40 CFR 191, Subpart B). Finally, guidance derived from the entire 1992 PA is presented in Volume 6. Results of the 1992 uncertainty and sensitivity analyses indicate that, conditional on the modeling assumptions and the assigned parameter-value distributions, the most important parameters for which uncertainty has the potential to affect gas and brine migration from the undisturbed repository are: initial liquid saturation in the waste, anhydrite permeability, biodegradation-reaction stoichiometry, gas-generation rates for both corrosion and biodegradation under inundated conditions, and the permeability of the long-term shaft seal.

  2. Changes in forebrain function from waking to REM sleep in depression: preliminary analyses of [18F]FDG PET studies.

    Science.gov (United States)

    Nofzinger, E A; Nichols, T E; Meltzer, C C; Price, J; Steppe, D A; Miewald, J M; Kupfer, D J; Moore, R Y

    1999-08-31

    Based on recent functional brain imaging studies of healthy human REM sleep, we hypothesized that alterations in REM sleep in mood disorder patients reflect a functional dysregulation within limbic and paralimbic forebrain structures during that sleep state. Six unipolar depressed subjects and eight healthy subjects underwent separate [18F]2-fluoro-2-deoxy-D-glucose ([18F]FDG) PET scans during waking and during their first REM period of sleep. Statistical parametric mapping contrasts were performed to detect changes in relative regional cerebral glucose metabolism (rCMRglu) from waking to REM sleep in each group as well as interactions in patterns of change between groups. Clinical and EEG sleep comparisons from an undisturbed night of sleep were also performed. In contrast to healthy control subjects, depressed patients did not show increases in rCMRglu in anterior paralimbic structures in REM sleep compared to waking. Depressed subjects showed greater increases from waking to REM sleep in rCMRglu in the tectal area and a series of left hemispheric areas including sensorimotor cortex, inferior temporal cortex, uncal gyrus-amygdala, and subicular complex than did the control subjects. These observations indicate that changes in limbic and paralimbic function from waking to REM sleep differ significantly from normal in depressed patients.

  3. Arsenic absorption by members of the Brassicacea family, analysed by neutron activation, k{sub 0}-method - preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Uemura, George; Matos, Ludmila Vieira da Silva; Silva, Maria Aparecida da; Ferreira, Alexandre Santos Martorano; Menezes, Maria Angela de Barros Correia [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN-CNEN/MG), Belo Horizonte, MG (Brazil)], e-mail: george@cdtn.br, e-mail: menezes@cdtn.br

    2009-07-01

    Natural arsenic contamination is a cause for concern in many countries of the world including Argentina, Bangladesh, Chile, China, India, Mexico, Thailand and the United States of America and also in Brazil, specially in the Iron Quadrangle area, where mining activities has been contributing to aggravate natural contamination. Brassicacea is a plant family with edible species (arugula, cabbage, cauliflower, cress, kale, mustard, radish), ornamental ones (alysssum, field pennycress, ornamental cabbages and kales) and some species are known as metal and metalloid accumulators (Indian mustard, field pennycress), like chromium, nickel, and arsenic. The present work aimed at studying other taxa of the Brassicaceae family to verify their capability in absorbing arsenic, under controlled conditions, for possible utilisation in remediation activities. The analytical method chosen was neutron activation analysis, k{sub 0} method, a routine technique at CDTN, and also very appropriate for arsenic studies. To avoid possible interference from solid substrates, like sand or vermiculite, attempts were carried out to keep the specimens in 1/4 Murashige and Skoog basal salt solution (M and S). Growth was stumped, plants withered and perished, showing that modifications in M and S had to be done. The addition of nickel and silicon allowed normal growth of the plant specimens, for periods longer than usually achieved (more than two months); yielding samples large enough for further studies with other techniques, like ICP-MS, and other targets, like speciation studies. The results of arsenic absorption are presented here and the need of nickel and silicon in the composition of M and S is discussed. (author)

  4. Expression, crystallization and preliminary X-ray crystallographic analyses of two N-terminal acetyltransferase-related proteins from Thermoplasma acidophilum

    Energy Technology Data Exchange (ETDEWEB)

    Han, Sang Hee; Ha, Jun Yong; Kim, Kyoung Hoon; Oh, Sung Jin; Kim, Do Jin; Kang, Ji Yong; Yoon, Hye Jin [Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151-742 (Korea, Republic of); Kim, Se-Hee; Seo, Ji Hae; Kim, Kyu-Won [NeuroVascular Coordination Research Center, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 151-742 (Korea, Republic of); Suh, Se Won, E-mail: sewonsuh@snu.ac.kr [Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151-742 (Korea, Republic of)

    2006-11-01

    An N-terminal acetyltransferase ARD1 subunit-related protein (Ta0058) and an N-terminal acetyltransferase-related protein (Ta1140) from T. acidophilum were crystallized. X-ray diffraction data were collected to 2.17 and 2.40 Å, respectively. N-terminal acetylation is one of the most common protein modifications in eukaryotes, occurring in approximately 80–90% of cytosolic mammalian proteins and about 50% of yeast proteins. ARD1 (arrest-defective protein 1), together with NAT1 (N-acetyltransferase protein 1) and possibly NAT5, is responsible for the NatA activity in Saccharomyces cerevisiae. In mammals, ARD1 is involved in cell proliferation, neuronal development and cancer. Interestingly, it has been reported that mouse ARD1 (mARD1{sup 225}) mediates ∊-acetylation of hypoxia-inducible factor 1α (HIF-1α) and thereby enhances HIF-1α ubiquitination and degradation. Here, the preliminary X-ray crystallographic analyses of two N-terminal acetyltransferase-related proteins encoded by the Ta0058 and Ta1140 genes of Thermoplasma acidophilum are reported. The Ta0058 protein is related to an N-terminal acetyltransferase complex ARD1 subunit, while Ta1140 is a putative N-terminal acetyltransferase-related protein. Ta0058 shows 26% amino-acid sequence identity to both mARD1{sup 225} and human ARD1{sup 235}.The sequence identity between Ta0058 and Ta1140 is 28%. Ta0058 and Ta1140 were overexpressed in Escherichia coli fused with an N-terminal purification tag. Ta0058 was crystallized at 297 K using a reservoir solution consisting of 0.1 M sodium acetate pH 4.6, 8%(w/v) polyethylene glycol 4000 and 35%(v/v) glycerol. X-ray diffraction data were collected to 2.17 Å. The Ta0058 crystals belong to space group P4{sub 1} (or P4{sub 3}), with unit-cell parameters a = b = 49.334, c = 70.384 Å, α = β = γ = 90°. The asymmetric unit contains a monomer, giving a calculated crystal volume per protein weight (V{sub M}) of 2.13 Å{sup 3} Da{sup −1} and a solvent content of 42

  5. Comparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct Classes

    OpenAIRE

    Fabian Kurth; Kieran Rimmer; Lakshmanane Premkumar; Biswaranjan Mohanty; Wilko Duprez; Halili, Maria A; Shouldice, Stephen R.; Begoña Heras; Fairlie, David P.; Martin J. Scanlon; Jennifer L Martin

    2013-01-01

    Bacterial DsbA enzymes catalyze oxidative folding of virulence factors, and have been identified as targets for antivirulence drugs. However, DsbA enzymes characterized to date exhibit a wide spectrum of redox properties and divergent structural features compared to the prototypical DsbA enzyme of Escherichia coli DsbA (EcDsbA). Nonetheless, sequence analysis shows that DsbAs are more highly conserved than their known substrate virulence factors, highlighting the potential to inhibit virulenc...

  6. 台湾综艺节目“误读大陆”原因浅析%Analyse of the causes Taiwan variety show"misreading mainland"

    Institute of Scientific and Technical Information of China (English)

    罗娟

    2014-01-01

    随着两岸关系的发展,两岸媒体间的交流也越来越多,台湾电视综艺节目中关于大陆的话题和大陆形象的塑造也成为人们关注的热点,研究发现,台湾电视综艺节目中存在不少对大陆的误读的现象,本文结合台湾的政治经济文化生活,从媒体自身的生存与运作规律、民众的收视心理和社会文化以及两岸之间的交流困境等不同角度探讨了这种误读现象出现的原因,以期能对两岸节目的交流和大陆对台传播等方面有所启示。%With the development of cross-strait relations, media on both sides of the Taiwan straits started communication also more and more. Taiwan television variety show about the topic of China mainland and image has become the focus of hot spots, the study found that Taiwan TV variety shows have some misreading phenomenon on mainland China, In this paper, combined with Taiwan's political, economic and cultural life from the survival and the operating rules of media itself, people's viewing psychology and social culture and communication difficulties between the two sides are discussed by different this misreading phenomenon comes. In order to program communication on both sides of the Taiwan and the mainland to Taiwan spread some enlightenment.

  7. Expression, Crystallization and Preliminary X-ray Diffraction Analyses of Med-ORF10 in the Biosynthetic Pathway of an Antitumor Antibiotic Medermycin.

    Science.gov (United States)

    Liu, Yanli; Liu, Shasha; Yang, Tingting; Guo, Xiaoxia; Jiang, Yali; Zahid, Kashif Rafiq; Liu, Ke; Liu, Jinlin; Yang, Jihong; Zhao, Haobin; Yang, Yi; Li, Aiying; Qi, Chao

    2015-12-01

    Medermycin, as a prominent member of benzoisochromanequinones, possesses strong antitumor activity and is biosynthesized under the control of a 29-ORF-containing biosynthetic gene cluster. Most of ORFs in this gene cluster have not been characterized, including a small protein encoding gene med-ORF10, proposed to play a regulatory role in biosynthesis of medermycin in an unknown mode. In this study, we reported the expression, protein preparation, crystallization and preliminary X-ray diffraction analyses of Med-ORF10 of the wild type Streptomyces strain. Firstly, we cloned and overexpressed med-ORF10 in Escherichia coli and purified the protein with 98% purity and 3 mg/L yield. Then, we crystallized the protein at concentration of 20 mg/mL in condition 22% PEG 3350, 0.2 M magnesium formate and collected the data at 1.78 Å resolution. Finally, we detected the expression of Med-ORF10 in Streptomyces by western blotting. In conclusion, this study confirmed the expression of Med-ORF10 protein in the wild-type strain of Streptomyces AM-7161 and collected the X-ray diffraction data of Med-ORF10 crystal at 1.78 Å resolution. These studies provide evidences for the functional Med-ORF10 protein in Streptomyces strains and facilitate our further investigation.

  8. GATA2 mutations in patients with acute myeloid leukemia-paired samples analyses show that the mutation is unstable during disease evolution.

    Science.gov (United States)

    Hou, Hsin-An; Lin, Yun-Chu; Kuo, Yuan-Yeh; Chou, Wen-Chien; Lin, Chien-Chin; Liu, Chieh-Yu; Chen, Chien-Yuan; Lin, Liang-In; Tseng, Mei-Hsuan; Huang, Chi-Fei; Chiang, Ying-Chieh; Liu, Ming-Chih; Liu, Chia-Wen; Tang, Jih-Luh; Yao, Ming; Huang, Shang-Yi; Ko, Bor-Sheng; Hsu, Szu-Chun; Wu, Shang-Ju; Tsay, Woei; Chen, Yao-Chang; Tien, Hwei-Fang

    2015-02-01

    Recently, mutations of the GATA binding protein 2 (GATA2) gene were identified in acute myeloid leukemia (AML) patients with CEBPA double mutations (CEBPA (double-mut)), but the interaction of this mutation with other genetic alterations and its dynamic changes during disease progression remain to be determined. In this study, 14 different missense GATA2 mutations, which were all clustered in the highly conserved N-terminal zinc finger 1 domain, were identified in 27.4, 6.7, and 1 % of patients with CEBPA (double-mut), CEBPA (single-mut), and CEBPA wild type, respectively. All but one patient with GATA2 mutation had concurrent CEBPA mutation. GATA2 mutations were closely associated with younger age, FAB M1 subtype, intermediate-risk cytogenetics, expression of HLA-DR, CD7, CD15, or CD34 on leukemic cells, and CEBPA mutation, but negatively associated with FAB M4 subtype, favorable-risk cytogenetics, and NPM1 mutation. Patients with GATA2 mutation had significantly better overall survival and relapse-free survival than those without GATA2 mutation. Sequential analysis showed that the original GATA2 mutations might be lost during disease progression in GATA2-mutated patients, while novel GATA2 mutations might be acquired at relapse in GATA2-wild patients. In conclusion, AML patients with GATA2 mutations had distinct clinic-biological features and a favorable prognosis. GATA2 mutations might be lost or acquired at disease progression, implying that it was a second hit in the leukemogenesis of AML, especially those with CEBPA mutation.

  9. Preliminary results on the tectonic activity of the Ovacık Fault (Malatya-Ovacık Fault Zone, Turkey): Implications of the morphometric analyses

    Science.gov (United States)

    Yazıcı, Müge; Zabci, Cengiz; Sançar, Taylan; Sunal, Gürsel; Natalin, Boris A.

    2016-04-01

    The Anatolian 'plate' is being extruded westward relative to the Eurasia along two major tectonic structures, the North Anatolian and the East Anatolian shear zones, respectively making its northern and eastern boundaries. Although the main deformation is localized along these two structures, there is remarkable intra-plate deformation within Anatolia, especially which are characterized by NE-striking sinistral and NW-striking dextral strike-slip faults (Şengör et al. 1985). The Malatya-Ovacık Fault Zone (MOFZ) and its northeastern member, the Ovacık Fault (OF), is a one of the NE-striking sinistral strike slip faults in the central 'ova' neotectonic province of Anatolia, located close to its eastern boundary. Although this fault zone is claimed to be an inactive structure in some studies, the recent GPS measurements (Aktuǧ et al., 2013) and microseismic activity (AFAD, 2013) strongly suggest the opposite. In order to understand rates and patterns of vertical ground motions along the OF, we studied the certain morphometric analyses such as hypsometric curves and integrals, longitudinal channel profiles, and asymmetry of drainage basins. The Karasu (Euphrates) and Munzur rivers form the main drainage systems of the study area. We extracted all drainage network from SRTM-based Digital Elevation Model with 30 m ground pixel resolution and totally identified 40 sub-drainage basins, which are inhomogeneously distributed to the north and to the south of the OF. Most of these basins show strong asymmetry, which are mainly tilted to SW. The asymmetry relatively decreases from NE to SW in general. The only exception is at the margins of the Ovacık Basin (OB), where almost the highest asymmetry values were calculated. On the other hand, the characteristics of hypsometric curves and the calculated hypsometric integrals do not show the similar systematic spatial pattern. The hypsometric curves with convex-shaped geometry, naturally indicating relatively young morphology

  10. Genetic Structure and Preliminary Findings of Cryptic Diversity of the Malaysian Mahseer (Tor tambroides Valenciennes: Cyprinidae Inferred from Mitochondrial DNA and Microsatellite Analyses

    Directory of Open Access Journals (Sweden)

    Yuzine Esa

    2013-01-01

    Full Text Available This study examines the population genetic structure of Tor tambroides, an important freshwater fish species in Malaysia, using fifteen polymorphic microsatellite loci and sequencing of 464 base pairs of the mitochondrial cytochrome c oxidase I (COI gene. A total of 152 mahseer samples were collected from eight populations throughout the Malaysia river system. Microsatellites results found high levels of intrapopulation variations, but mitochondrial COI results found high levels of interpopulations differentiation. The possible reasons for their discrepancies might be the varying influence of genetic drift on each marker or the small sample sizes used in most of the populations. The Kelantan population showed very low levels of genetic variations using both mitochondrial and microsatellite analyses. Phylogenetic analysis of the COI gene found a unique haplotype (ER8*, possibly representing a cryptic lineage of T. douronensis, from the Endau-Rompin population. Nevertheless, the inclusion of nuclear microsatellite analyses could not fully resolve the genetic identity of haplotype ER8* in the present study. Overall, the findings showed a serious need for more comprehensive and larger scale samplings, especially in remote river systems, in combination with molecular analyses using multiple markers, in order to discover more cryptic lineages or undescribed “genetic species” of mahseer.

  11. X inactivation in Rett syndrome: A preliminary study showing partial preferential inactivation of paternal X with the M27{beta} probe

    Energy Technology Data Exchange (ETDEWEB)

    Camus, P.; Abbadi, N.; Gilgenkrantz, S. [Laboratoire de Genetique, Vandoeuvre les Nancy (France)

    1994-04-15

    Rett syndrome (RS) is a severe progressive neurological disorder occurring exclusively in females. Most cases are sporadic. The few familial cases (less than 1%) cannot be explained by a simple mode of inheritance. Several hypotheses have been proposed: X-linked male lethal mutation, maternal uniparental disomy, fresh mutation on the X chromosome, involvement of mitochondrial DNA and differential inactivation with metabolic interference of X-borne alleles. The authors have examined the pattern of X inactivation in 10 affected girls who were selected according to the clinical criteria previously described and accepted by the French Rett Scientific Committee. The X inactivation pattern was studied by analysis of methylation at the hypervariable locus DXS255 with the M27{beta} probe. The results show a more-or-less skewed inactivation of paternal X in 8 Rett females, and 2 cases of symmetrical inactivation. In control girls, inactivation was symmetrical cases and the maternal X has been preferentially inactivated in the other 2 cases. In no case was a total skewed inactivation observed. Though there was clear evidence for a preferential paternal X inactivation that was statistically significant further studies are necessary to establish a relationship between X inactivation pattern and Rett syndrome.

  12. Analyses of hydrocarbons in BLM sediment intercalibration sample from Santa Barbara basin and spiked with API South Louisiana crude oil. A preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    Farrington, J W; Tripp, B W; Sass, J

    1977-01-01

    A preliminary report is made of a BLM intercalibration sediment sample from the Santa Barbara basin spiked with South Louisiana crude oil. The two subsamples reported were analyzed by a procedure described in the appendix for which a separate abstract was written. Because of the high oil content of the sediment the usual thin layer chromatography procedure resulted in an overloaded plate. An appendix was indexed separately. (JSR)

  13. Show Time

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    <正> Story: Show Time!The whole class presents the story"Under the Sea".Everyone is so excited and happy.Both Leo and Kathy show their parentsthe characters of the play."Who’s he?"asks Kathy’s mom."He’s the prince."Kathy replies."Who’s she?"asks Leo’s dad."She’s the queen."Leo replieswith a smile.

  14. Snobbish Show

    Institute of Scientific and Technical Information of China (English)

    YIN PUMIN

    2010-01-01

    @@ The State Administration of Radio,Film and Television (SARFT),China's media watchdog,issued a new set of mles on June 9 that strictly regulate TV match-making shows,which have been sweeping the country's primetime programming. "Improper social and love values such as money worship should not be presented in these shows.Humiliation,verbal attacks and sex-implied vulgar content are not allowed" the new roles said.

  15. EROBATIC SHOW

    Institute of Scientific and Technical Information of China (English)

    2016-01-01

    Visitors look at plane models of the Commercial Aircraft Corp. of China, developer of the count,s first homegrown large passenger jet C919, during the Singapore Airshow on February 16. The biennial event is the largest airshow in Asia and one of the most important aviation and defense shows worldwide. A number of Chinese companies took part in the event during which Okay Airways, the first privately owned aidine in China, signed a deal to acquire 12 Boeing 737 jets.

  16. 浅谈现代舞台表演武术与舞蹈元素的融合%Analyses the Fusion of Modern Martial Arts Stage Show and Dance Elements

    Institute of Scientific and Technical Information of China (English)

    陈芳

    2012-01-01

    Along with the progress of the society, people's aesthetic standard have changed, martial arts stage show from the simple in form and other routine drills to fusion others art element , for exam- ple, music element fusion, calligraphy elements fusion, opera ele- ments fusion and dance elements fusion, etc. This paper from the beauty of formal, beauty of the musical sound, the beauty of artistic conception three aspects to analyses the fusion of modem martial arts stage show and dance elements.%随着社会的进步,人们的审美观发生了很大的变化,武术的舞台表演形式也从简单的套路演练到与其它艺术元素的相互融合。比如,与音乐元素的融合、与书法元素的融合、与戏曲元素的融合、与舞蹈元素的融合等。本文将从形式美、韵之美、意境美三方面探讨现在舞台表演武术与舞蹈元素的融合。

  17. Preliminary performance assessment for the Waste Isolation Pilot Plant, December 1992. Volume 4: Uncertainty and sensitivity analyses for 40 CFR 191, Subpart B

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-01

    Before disposing of transuranic radioactive waste in the Waste Isolation Pilot Plant (WIPP), the United States Department of Energy (DOE) must evaluate compliance with applicable long-term regulations of the United States Environmental Protection Agency (EPA). Sandia National Laboratories is conducting iterative performance assessments (PAs) of the WIPP for the DOE to provide interim guidance while preparing for a final compliance evaluation. This volume of the 1992 PA contains results of uncertainty and sensitivity analyses with respect to the EPA`s Environmental Protection Standards for Management and Disposal of Spent Nuclear Fuel, High-Level and Transuranic Radioactive Wastes (40 CFR 191, Subpart B). Additional information about the 1992 PA is provided in other volumes. Results of the 1992 uncertainty and sensitivity analyses indicate that, conditional on the modeling assumptions, the choice of parameters selected for sampling, and the assigned parameter-value distributions, the most important parameters for which uncertainty has the potential to affect compliance with 40 CFR 191B are: drilling intensity, intrusion borehole permeability, halite and anhydrite permeabilities, radionuclide solubilities and distribution coefficients, fracture spacing in the Culebra Dolomite Member of the Rustler Formation, porosity of the Culebra, and spatial variability of Culebra transmissivity. Performance with respect to 40 CFR 191B is insensitive to uncertainty in other parameters; however, additional data are needed to confirm that reality lies within the assigned distributions.

  18. The Added Value of Log File Analyses of the Use of a Personal Health Record for Patients With Type 2 Diabetes Mellitus: Preliminary Results.

    Science.gov (United States)

    Sieverink, Floor; Kelders, Saskia M; Braakman-Jansen, Louise M A; van Gemert-Pijnen, Julia E W C

    2014-03-01

    The electronic personal health record (PHR) is a promising technology for improving the quality of chronic disease management. Until now, evaluations of such systems have provided only little insight into why a particular outcome occurred. The aim of this study is to gain insight into the navigation process (what functionalities are used, and in what sequence) of e-Vita, a PHR for patients with type 2 diabetes mellitus (T2DM), to increase the efficiency of the system and improve the long-term adherence. Log data of the first visits in the first 6 weeks after the release of a renewed version of e-Vita were analyzed to identify the usage patterns that emerge when users explore a new application. After receiving the invitation, 28% of all registered users visited e-Vita. In total, 70 unique usage patterns could be identified. When users visited the education service first, 93% of all users ended their session. Most users visited either 1 or 5 or more services during their first session, but the distribution of the routes was diffuse. In conclusion, log file analyses can provide valuable prompts for improving the system design of a PHR. In this way, the match between the system and its users and the long-term adherence has the potential to increase.

  19. Stardust Interstellar Preliminary Examination IV: Scanning transmission X-ray microscopy analyses of impact features in the Stardust Interstellar Dust Collector

    Science.gov (United States)

    Butterworth, Anna L.; Westphal, Andrew J.; Tyliszczak, Tolek; Gainsforth, Zack; Stodolna, Julien; Frank, David R.; Allen, Carlton; Anderson, David; Ansari, Asna; Bajt, SašA.; Bastien, Ron K.; Bassim, Nabil; Bechtel, Hans A.; Borg, Janet; Brenker, Frank E.; Bridges, John; Brownlee, Donald E.; Burchell, Mark; Burghammer, Manfred; Changela, Hitesh; Cloetens, Peter; Davis, Andrew M.; Doll, Ryan; Floss, Christine; Flynn, George; Grün, Eberhard; Heck, Philipp R.; Hillier, Jon K.; Hoppe, Peter; Hudson, Bruce; Huth, Joachim; Hvide, Brit; Kearsley, Anton; King, Ashley J.; Lai, Barry; Leitner, Jan; Lemelle, Laurence; Leroux, Hugues; Leonard, Ariel; Lettieri, Robert; Marchant, William; Nittler, Larry R.; Ogliore, Ryan; Ong, Wei Ja; Postberg, Frank; Price, Mark C.; Sandford, Scott A.; Tresseras, Juan-Angel Sans; Schmitz, Sylvia; Schoonjans, Tom; Silversmit, Geert; Simionovici, Alexandre S.; Solé, Vicente A.; Srama, Ralf; Stadermann, Frank J.; Stephan, Thomas; Sterken, Veerle J.; Stroud, Rhonda M.; Sutton, Steven; Trieloff, Mario; Tsou, Peter; Tsuchiyama, Akira; Vekemans, Bart; Vincze, Laszlo; von Korff, Joshua; Wordsworth, Naomi; Zevin, Daniel; Zolensky, Michael E.

    2014-09-01

    We report the quantitative characterization by synchrotron soft X-ray spectroscopy of 31 potential impact features in the aerogel capture medium of the Stardust Interstellar Dust Collector. Samples were analyzed in aerogel by acquiring high spatial resolution maps and high energy-resolution spectra of major rock-forming elements Mg, Al, Si, Fe, and others. We developed diagnostic screening tests to reject spacecraft secondary ejecta and terrestrial contaminants from further consideration as interstellar dust candidates. The results support an extraterrestrial origin for three interstellar candidates: I1043,1,30 (Orion) is a 3 pg particle with Mg-spinel, forsterite, and an iron-bearing phase. I1047,1,34 (Hylabrook) is a 4 pg particle comprising an olivine core surrounded by low-density, amorphous Mg-silicate and amorphous Fe, Cr, and Mn phases. I1003,1,40 (Sorok) has the track morphology of a high-speed impact, but contains no detectable residue that is convincingly distinguishable from the background aerogel. Twenty-two samples with an anthropogenic origin were rejected, including four secondary ejecta from impacts on the Stardust spacecraft aft solar panels, nine ejecta from secondary impacts on the Stardust Sample Return Capsule, and nine contaminants lacking evidence of an impact. Other samples in the collection included I1029,1,6, which contained surviving solar system impactor material. Four samples remained ambiguous: I1006,2,18, I1044,2,32, and I1092,2,38 were too dense for analysis, and we did not detect an intact projectile in I1044,3,33. We detected no radiation effects from the synchrotron soft X-ray analyses; however, we recorded the effects of synchrotron hard X-ray radiation on I1043,1,30 and I1047,1,34.

  20. Crystallization and preliminary X-ray diffraction analyses of the TIR domains of three TIR-NB-LRR proteins that are involved in disease resistance in Arabidopsis thaliana.

    Science.gov (United States)

    Wan, Li; Zhang, Xiaoxiao; Williams, Simon J; Ve, Thomas; Bernoux, Maud; Sohn, Kee Hoon; Jones, Jonathan D G; Dodds, Peter N; Kobe, Bostjan

    2013-11-01

    The Toll/interleukin-1 receptor (TIR) domain is a protein-protein interaction domain that is found in both animal and plant immune receptors. The N-terminal TIR domain from the nucleotide-binding (NB)-leucine-rich repeat (LRR) class of plant disease-resistance (R) proteins has been shown to play an important role in defence signalling. Recently, the crystal structure of the TIR domain from flax R protein L6 was determined and this structure, combined with functional studies, demonstrated that TIR-domain homodimerization is a requirement for function of the R protein L6. To advance the molecular understanding of the function of TIR domains in R-protein signalling, the protein expression, purification, crystallization and X-ray diffraction analyses of the TIR domains of the Arabidopsis thaliana R proteins RPS4 (resistance to Pseudomonas syringae 4) and RRS1 (resistance to Ralstonia solanacearum 1) and the resistance-like protein SNC1 (suppressor of npr1-1, constitutive 1) are reported here. RPS4 and RRS1 function cooperatively as a dual resistance-protein system that prevents infection by three distinct pathogens. SNC1 is implicated in resistance pathways in Arabidopsis and is believed to be involved in transcriptional regulation through its interaction with the transcriptional corepressor TPR1 (Topless-related 1). The TIR domains of all three proteins have successfully been expressed and purified as soluble proteins in Escherichia coli. Plate-like crystals of the RPS4 TIR domain were obtained using PEG 3350 as a precipitant; they diffracted X-rays to 2.05 Å resolution, had the symmetry of space group P1 and analysis of the Matthews coefficient suggested that there were four molecules per asymmetric unit. Tetragonal crystals of the RRS1 TIR domain were obtained using ammonium sulfate as a precipitant; they diffracted X-rays to 1.75 Å resolution, had the symmetry of space group P4(1)2(1)2 or P4(3)2(1)2 and were most likely to contain one molecule per asymmetric

  1. 菠萝皮渣的营养成分分析及利用的研究%Nutrient analyses and preliminary application of pineapple by-products

    Institute of Scientific and Technical Information of China (English)

    吕庆芳; 王润莲

    2011-01-01

    探讨了菠萝加工副产物菠萝皮渣的营养价值及饲用效果.采用国家标准方法测定了菠萝加工副产物菠萝皮渣的常规营养成分,并将其以不同梯度配入贵妃鸡日粮中,观测对鸡生长、采食量及胴体性能的影响.结果表明,菠萝皮渣饲料中无氮浸出物和纤维含量较高,分别为45.37%、27.70%;钙含量中等偏上为0.54%;蛋白、脂肪和磷含量偏低,分别为7.60%、2.40%、0.06%;并含多种矿物元素.贵妃鸡日粮中使用2.5%的菠萝皮渣不影响生长和胴体性能,但添加量增加至5%时,贵妃鸡的采食量稍有下降、生长速度变慢,饲料利用效率有所降低,腿肌率、腹脂率和皮脂厚有降低的趋势.可见,菠萝皮渣含有丰富的营养物质,可作为能量饲料应用到贵妃鸡日粮中,其添加量以2.5%左右为宜.%This experiment was conducted to evaluate the nutritional value and feeding effects of pineapple by-products in Princess chickens. The composition of pineapple by-products was determined by proximate analysis using the national standard methods, and changes in growth performance, feed intake and the carcass characteristics were investigated by supplementation of pineapple by-products at a level of 2.5% or 5% in diet of Princess chickens. Results showed that pineapple by-products contained non-protein nitrogen, crude fiber, crude protein, ether extract, calcium and phosphorus at the level of 45.37%,27.70%, 7.60%, 2.40%, 0.54% and 0.06% respectively. Pineapple by-products supplementation at the level of 2.5% in diet of Princess chickens showed no influence on growth and carcass characteristics,while 5% supplementation significantly decreased the feed intake, growth and feed conversion rate, and tended to decrease the leg muscle percentage, abdominal fat percentage and subcutaneous fat of Princess chickens. In conclusion, the pineapple by-product could be applied in diet of Princess chickens as a feedstuff due to a

  2. A Raman lidar at La Reunion (20.8° S, 55.5° E for monitoring water vapour and cirrus distributions in the subtropical upper troposphere: preliminary analyses and description of a future system

    Directory of Open Access Journals (Sweden)

    C. Hoareau

    2012-06-01

    Full Text Available A ground-based Rayleigh lidar has provided continuous observations of tropospheric water vapour profiles and cirrus cloud using a preliminary Raman channels setup on an existing Rayleigh lidar above La Reunion over the period 2002–2005. With this instrument, we performed a first measurement campaign of 350 independent water vapour profiles. A statistical study of the distribution of water vapour profiles is presented and some investigations concerning the calibration are discussed. Analysis regarding the cirrus clouds is presented and a classification has been performed showing 3 distinct classes. Based on these results, the characteristics and the design of a future lidar system, to be implemented at the new Reunion Island altitude observatory (2200 m for long-term monitoring, is presented and numerical simulations of system performance have been realised to compare both instruments.

  3. Crystallization and preliminary X-ray diffraction analyses of pseudechetoxin and pseudecin, two snake-venom cysteine-rich secretory proteins that target cyclic nucleotide-gated ion channels

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Nobuhiro [Institute of Applied Biochemistry, University of Tsukuba, Tsukuba, Ibaraki 305-8572 (Japan); Department of Biochemistry, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki 305-8602 (Japan); Yamazaki, Yasuo [Department of Biochemistry, Meiji Pharmaceutical University, Kiyose, Tokyo 204-8588 (Japan); Fujimoto, Zui [Department of Biochemistry, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki 305-8602 (Japan); Morita, Takashi [Department of Biochemistry, Meiji Pharmaceutical University, Kiyose, Tokyo 204-8588 (Japan); Mizuno, Hiroshi, E-mail: mizuno-hiroshi@aist.go.jp [Department of Biochemistry, National Institute of Agrobiological Sciences, Tsukuba, Ibaraki 305-8602 (Japan); VALWAY Technology Center, NEC Soft Ltd, Koto-ku, Tokyo 136-8627 (Japan); Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology, Central 6, Tsukuba, Ibaraki 305-8566 (Japan); Institute of Applied Biochemistry, University of Tsukuba, Tsukuba, Ibaraki 305-8572 (Japan)

    2005-08-01

    Crystals of pseudechetoxin and pseudecin, potent peptidic inhibitors of cyclic nucleotide-gated ion channels, have been prepared and X-ray diffraction data have been collected to 2.25 and 1.90 Å resolution, respectively. Cyclic nucleotide-gated (CNG) ion channels play pivotal roles in sensory transduction of retinal and olfactory neurons. The elapid snake toxins pseudechetoxin (PsTx) and pseudecin (Pdc) are the only known protein blockers of CNG channels. These toxins are structurally classified as cysteine-rich secretory proteins and exhibit structural features that are quite distinct from those of other known small peptidic channel blockers. This article describes the crystallization and preliminary X-ray diffraction analyses of these toxins. Crystals of PsTx belonged to space group P2{sub 1}2{sub 1}2{sub 1}, with unit-cell parameters a = 60.30, b = 61.59, c = 251.69 Å, and diffraction data were collected to 2.25 Å resolution. Crystals of Pdc also belonged to space group P2{sub 1}2{sub 1}2{sub 1}, with similar unit-cell parameters a = 60.71, b = 61.67, c = 251.22 Å, and diffraction data were collected to 1.90 Å resolution.

  4. Histograms showing variations in oil yield, water yield, and specific gravity of oil from Fischer assay analyses of oil-shale drill cores and cuttings from the Piceance Basin, northwestern Colorado

    Science.gov (United States)

    Dietrich, John D.; Brownfield, Michael E.; Johnson, Ronald C.; Mercier, Tracey J.

    2014-01-01

    Recent studies indicate that the Piceance Basin in northwestern Colorado contains over 1.5 trillion barrels of oil in place, making the basin the largest known oil-shale deposit in the world. Previously published histograms display oil-yield variations with depth and widely correlate rich and lean oil-shale beds and zones throughout the basin. Histograms in this report display oil-yield data plotted alongside either water-yield or oil specific-gravity data. Fischer assay analyses of core and cutting samples collected from exploration drill holes penetrating the Eocene Green River Formation in the Piceance Basin can aid in determining the origins of those deposits, as well as estimating the amount of organic matter, halite, nahcolite, and water-bearing minerals. This report focuses only on the oil yield plotted against water yield and oil specific gravity.

  5. Review: Martin Spetsmann-Kunkel (2004. Die Moral der Daytime Talkshow. Eine soziologische Analyse eines umstrittenen Fernsehformats [The Morality of the Daytime Talk Show. A Sociological Analysis of a Controversial Television Format

    Directory of Open Access Journals (Sweden)

    Nicola Döring

    2006-05-01

    Full Text Available This book deals with the phenomenon of the daytime talk show from a sociological perspective. The author questions the common cultural pessimism of this TV format ("exhibitionist guests," "voyeuristic spectators". He first describes the characteristics of the daytime talk show and summarizes the results of previous surveys that reveal a broad variety of talk show guests' and recipients' motives—beyond pathology. Drawing on concepts like civilization and individualisation, the book outlines the societal functions of the daytime talk show. A participatory observation study in the editorial office of "Hans Meiser" and free interpretations of three series from "Vera am Mittag" are presented as "empirical evidence." Unfortunately the book lacks theoretical and methodological rigor and a sound empirical basis. The bibliography could have been more comprehensive. The work is useful, though, as an inspired, readable introduction into the topic. URN: urn:nbn:de:0114-fqs0603119

  6. The "Life Potential": a new complex algorithm to assess "Heart Rate Variability" from Holter records for cognitive and diagnostic aims. Preliminary experimental results showing its dependence on age, gender and health conditions

    CERN Document Server

    Barra, Orazio A

    2013-01-01

    Although HRV (Heart Rate Variability) analyses have been carried out for several decades, several limiting factors still make these analyses useless from a clinical point of view. The present paper aims at overcoming some of these limits by introducing the "Life Potential" (BMP), a new mathematical algorithm which seems to exhibit surprising cognitive and predictive capabilities. BMP is defined as a linear combination of five HRV Non-Linear Variables, in turn derived from the thermodynamic formalism of chaotic dynamic systems. The paper presents experimental measurements of BMP (Average Values and Standard Deviations) derived from 1048 Holter tests, matched in age and gender, including a control group of 356 healthy subjects. The main results are: (a) BMP always decreases when the age increases, and its dependence on age and gender is well established; (b) the shape of the age dependence within "healthy people" is different from that found in the general group: this behavior provides evidence of possible illn...

  7. Radiotoxicological analyses of {sup 239+240}Pu and {sup 241}Am in biological samples by anion-exchange and extraction chromatography: a preliminary study for internal contamination evaluations

    Energy Technology Data Exchange (ETDEWEB)

    Ridone, S.; Arginelli, D.; Bortoluzzi, S.; Canuto, G.; Montalto, M.; Nocente, M.; Vegro, M. [Italian National Agency for New Technologies, Energy and the Environment (ENEA), Research Centre of Saluggia, Radiation Protection Institute, Saluggia, VC (Italy)

    2006-07-01

    Many biological samples (urines and faeces) have been analysed by means of chromatographic extraction columns, utilising two different resins (AG 1-X2 resin chloride and T.R.U.), in order to detect the possible internal contamination of {sup 239{sup +}}{sup 240}Pu and {sup 241}Am, for some workers of a reprocessing nuclear plant in the decommissioning phase. The results obtained show on one hand the great suitability of the first resin for the determination of plutonium, and on the other the great selectivity of the second one for the determination of americium.

  8. Kvalitative analyser ..

    DEFF Research Database (Denmark)

    Boolsen, Merete Watt

    bogen forklarer de fundamentale trin i forskningsprocessen og applikerer dem på udvalgte kvalitative analyser: indholdsanalyse, Grounded Theory, argumentationsanalyse og diskursanalyse......bogen forklarer de fundamentale trin i forskningsprocessen og applikerer dem på udvalgte kvalitative analyser: indholdsanalyse, Grounded Theory, argumentationsanalyse og diskursanalyse...

  9. Chemical Analyses

    Science.gov (United States)

    Bulluck, J. W.; Rushing, R. A.

    1994-01-01

    As a preliminary study on the effects of chemical aging of polymer materials MERL and TRI have examined two polymeric materials that are typically used for offshore umbilical applications. These two materials were Tefzel, a copolymer of ethylene and tetrafluoroethylene, and Coflon, polyvinylidene fluoride. The Coflon specimens were cut from pipe sections and exposed to H2S at various temperatures and pressures. One of these specimens was tested for methane permeation, and another for H2S permeation. The Tefzel specimens were cut from .05 mm sheet stock material and were exposed to methanol at elevated temperature and pressure. One of these specimens was exposed to methanol permeation for 2 days at 100 C and 2500 psi. An additional specimen was exposed to liquid methanol for 3 days at 150 C and 15 Bar. Virgin specimens of each material were similarly prepared and tested.

  10. Contaminação do ambiente aquático por pesticidas. Estudo de caso: águas usadas para consumo humano em Primavera do Leste, Mato Grosso - análise preliminar Aquatic environment contamination by pesticides. Case study: water used for human consumption in Primavera do Leste, Mato Grosso - preliminary analyses

    Directory of Open Access Journals (Sweden)

    Eliana Freire Gaspar de Carvalho Dores

    2001-02-01

    Full Text Available A preliminary analyses of the possible contamination of superficial and underground water by the active ingredients of the pesticide products used in the surroundings of the urban area of Primavera do Leste, Mato Grosso, Brazil, was carried out. A description of the study region and of its environmental characteristics, which can favor the contamination of the local aquatic environment, was presented. The EPA screening criteria, the groundwater ubiquity score (GUS and the criteria proposed by Goss were used to evaluate which pesticides might contaminate the local waters. Among the active ingredients studied, several present risks to the local aquatic environment.

  11. Risk Aversion in Game Shows

    DEFF Research Database (Denmark)

    Andersen, Steffen; Lau, Morten I.; Rutström, E. Elisabet

    2008-01-01

    , and the dynamic nature of the task in most games. We consider the game shows Card Sharks, Jeopardy!, Lingo, and finally Deal Or No Deal. We provide a detailed case study of the analyses of Deal Or No Deal, since it is suitable for inference about risk attitudes and has attracted considerable attention....

  12. Preliminary verification of structure design for CN HCCB TBM with 1 × 4 configuration

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Zhou, E-mail: zhaozhou@swip.ac.cn; Zhou, Bing; Wang, Qijie; Cao, Qixiang; Feng, Kaiming; Wang, Xiaoyu; Zhang, Guoshu

    2016-02-15

    Highlights: • A new and simplification structural design scheme with 1 × 4 configuration is proposed for CN HCCB TBM. • The detail conceptual structural design for 1 × 4 TBM is completed. • The preliminary hydraulic analysis, thermo-hydraulic analysis and structural analysis for 1 × 4 TBM had been carried out. - Abstract: Based on the conceptual design of CN HCCB TBM with 1 × 4 configuration, the preliminary hydraulic analysis, thermo-hydraulic analysis and structural analysis had been carried out for it. Hydraulic and thermo-hydraulic analyses show that the coolant manifold system could meet the fluid design requirement preliminarily and the temperature of RAFMs structural parts, Be and Li{sub 4}SiO{sub 4} pebble beds are within the allowable range, and no zone shows a stress higher than the allowable limit in the preliminary structural analysis. These results indicate the design for CN HCCB TBM with 1 × 4 configuration is preliminary reasonable.

  13. Risk Aversion in Game Shows

    DEFF Research Database (Denmark)

    2008-01-01

    We review the use of behavior from television game shows to infer risk attitudes. These shows provide evidence when contestants are making decisions over very large stakes, and in a replicated, structured way. Inferences are generally confounded by the subjective assessment of skill in some games......, and the dynamic nature of the task in most games. We consider the game shows Card Sharks, Jeopardy!, Lingo, and finally Deal Or No Deal. We provide a detailed case study of the analyses of Deal Or No Deal, since it is suitable for inference about risk attitudes and has attracted considerable attention....

  14. 商標侵權案件定暫時狀態處分審酌因素之釋明──以eBay案後美國法發展與我國判決實務為中心 The Preliminary Showing on the Factors of Preliminary Injunction in Trademark Infringement Cases─Focusing on American Law after the eBay Case and Taiwan Court Decisions

    Directory of Open Access Journals (Sweden)

    范智達 Jr-Da Fan

    2015-12-01

    要求原告花費額外資源去釋明本案勝訴可能性以外之其他因素事實。 In eBay v. MercExchange (2006, the U.S. Supreme Court held that courts must apply the traditional four-factor test for injunctive relief in every case. These “principles of equity” required courts to employ the traditional four-factor test under which the plaintiff must demonstrate (1 a likelihood of success of the merits; (2 the existence of irreparable harm; (3 that the balance of hardships tilts in favor of injunctive relief; and (4 that granting an injunction would not harm the public interest. But when assessing whether a particular instance of trademark infringement resulted in “irreparable harm” U.S. federal courts almost uniformly presumed such irreparable harm upon a finding of likelihood of confusion. In fact, the eBay rules should not be used to eviscerate the normal presumption of irreparable harm that attaches upon a showing of liability in trademark cases. In our country when granting or denying preliminary injunction of trademark infringement cases, the plaintiff often provides a preliminary showing with regard to the existence of legal relation and trademark infringement documentary evidence, not actively providing the existence of irreparable harm, that the balance of hardships tilts in favor of injunctive relief and that an injunction is in the public interest. The court reviewing an application for preliminary injunction deliberates on the likelihood of success on the merits as the most important consideration. Compared with patent and copyright cases of the discretion of the preliminary injunction, the court mainly deliberates on the likelihood of success and the existence of irreparable harm as the most important factor. It is clear intellectual property cases, especially trademark cases on the set of preliminary injunction claim, do not require the plaintiff to take the burden of all factors of trial discretion in Taiwan. Because these harms to

  15. The Health Show

    OpenAIRE

    Swann, David

    2011-01-01

    Dr David Swann interviewed on The Health Show, Series 1, Episode 5, 2011 for BBC World about the award-winning 21st Century Nursing Bag. BBC World News reaches 241million people every week, available in 296 million homes, 1.8 million hotel rooms and has the highest average viewership on a weekday of any international news channel. The Health Show is a new 26-part series for BBC World News covering the most important news stories from around the world.

  16. A Fashion Show

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    <正>Story: The yearly fashion show day.The children take turns to walk on the stage and show the class their favorite clothes.Now it’s Joe’s and Phoebe’s turn.Joe walks on the stage and says,“My shorts are blue.Do you like my blue shorts?”On the other side of the stage, Phoebe is wearing her favorite pink skirt.“My skirt is pink.Do you like my pink skirt?”asks

  17. On not showing scalps

    DEFF Research Database (Denmark)

    Marselis, Randi Lorenz

    2016-01-01

    proposed by Janet Marstine, the editor of the Routledge Companion to Museum Ethics, I show how the museum succeeded in engaging users in questions of museum ethics. However, this specific debate on human remains in museums developed into an encounter between a global, museological discourse...

  18. Violence and TV Shows

    OpenAIRE

    ÖZTÜRK, Yrd. Doç. Dr. Şinasi

    2008-01-01

    This study aims to discuss theories on theviolent effects of TV shows on viewers, especiallyon children. Therefore, this study includes a briefdiscussion of definitions of violence, discussionof violence theories, main results of researcheson televised violence, measuring TV violence,perception of televised violence, individualdifferences and reactions to TV violence,aggressiveness and preferences for TV violence.

  19. Honored Teacher Shows Commitment.

    Science.gov (United States)

    Ratte, Kathy

    1987-01-01

    Part of the acceptance speech of the 1985 National Council for the Social Studies Teacher of the Year, this article describes the censorship experience of this honored social studies teacher. The incident involved the showing of a videotape version of the feature film entitled "The Seduction of Joe Tynan." (JDH)

  20. A Visionary Show

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Seduction. Distinction. Relax. Pulsation. These are the "style universes" on display at Première Vision, heralded as "The World’s Premiere Fabric Show." Started more than 35 years ago by 15 French weavers, Première Vision has expanded beyond its

  1. Honored Teacher Shows Commitment.

    Science.gov (United States)

    Ratte, Kathy

    1987-01-01

    Part of the acceptance speech of the 1985 National Council for the Social Studies Teacher of the Year, this article describes the censorship experience of this honored social studies teacher. The incident involved the showing of a videotape version of the feature film entitled "The Seduction of Joe Tynan." (JDH)

  2. PRELIMINARY PALAEOSYNECOLOGICAL ANALYSES ON THE UPPER ANISIAN (MIDDLE TRIASSIC)QINGYAN FAUNA%中三叠世青岩生物群的群体古生态学初步研究

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The Qingyan fauna (Upper Anisian, Middle Triassic) was found from a section located at about 30km south of Guiyang, the provincial capital of Guizhou Province, SW China. Here yields abundant well-preserved and highly diversed fossils, involving 16-17 groups of organisms, among which gastropods, frachiopods and bivalves are dominant. Some macrofossils are a eommon sight here including corals, sponges, crinoids, scaphapods, ammonoids, nautilids, bryozoaus and echinoids. whereas others such as porifers, cnidarians and annelids are rare in occurrence but visible sometimes. Among microfossils abounded in this fauna, snch groups as ostracods, foraminiferans and calcareous algae were analysed.   After a palaeosynecologic study combining with palaeogeographic analyses we believe that the Qingyan fauna might have developed in an environment of a protected shallow marine habitat, which was lacated at a position of the upper part of basin slope. The sea bottom was fine-grained and stable. The rates of sedimentation were generally relatively low. The water was relatively deep and the organisms lived in the photic zone above the storm wave base and below the fair-weather wave base.   Epibenthic forms are the main groups in this primarily benthic fauna. Shallow burrowing in fauna and semiinfauna form smaller portions. In traphic habits, suspension-feeders are the dominant group. In a ddition, there are herbivores (gastropods), detritus-feeders, scavengers, and omnivores, a few deposit-feeders and few micro- and macro-carnivores.   The high percentage of suspension-feeders in the fauna indicates that the water was clean and clear, gently moving, and rich in oxygen and nutrients. The highly diverse associations, especially bivalves and gastropods, most probablyre present selics of community which had lived in patches of macroalgae.%根据群体古生态学的初步研究,认为青岩生物群的富集是因为发育一个较为特殊的生态环境,即位于斜坡

  3. Shanghai Shows Its Heart

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The city known as China’s economic powerhouse showed a more caring face as host of the Special Olympic Games Between October 2 and 11,the Special Olympics Summer Games were hosted in Shanghai,the first time the 40-year-old athletic com- petition for people with intellectual disabilities came to a developing country. This Special Olympics was also larger than all previous games in temps of the number of athletes.

  4. Not a "reality" show.

    Science.gov (United States)

    Wrong, Terence; Baumgart, Erica

    2013-01-01

    The authors of the preceding articles raise legitimate questions about patient and staff rights and the unintended consequences of allowing ABC News to film inside teaching hospitals. We explain why we regard their fears as baseless and not supported by what we heard from individuals portrayed in the filming, our decade-long experience making medical documentaries, and the full un-aired context of the scenes shown in the broadcast. The authors don't and can't know what conversations we had, what documents we reviewed, and what protections we put in place in each televised scene. Finally, we hope to correct several misleading examples cited by the authors as well as their offhand mischaracterization of our program as a "reality" show.

  5. Showing Value (Editorial

    Directory of Open Access Journals (Sweden)

    Denise Koufogiannakis

    2009-06-01

    Full Text Available When Su Cleyle and I first decided to start Evidence Based Library and Information Practice, one of the things we agreed upon immediately was that the journal be open access. We knew that a major obstacle to librarians using the research literature was that they did not have access to the research literature. Although Su and I are both academic librarians who can access a wide variety of library and information literature from our institutions, we belong to a profession where not everyone has equal access to the research in our field. Without such access to our own body of literature, how can we ever hope for practitioners to use research evidence in their decision making? It would have been contradictory to the principles of evidence based library and information practice to do otherwise.One of the specific groups we thought could use such an open access venue for discovering research literature was school librarians. School librarians are often isolated and lacking access to the research literature that may help them prove to stakeholders the importance of their libraries and their role within schools. Certainly, school libraries have been in decline and the use of evidence to show value is needed. As Ken Haycock noted in his 2003 report, The Crisis in Canada’s School Libraries: The Case for Reform and Reinvestment, “Across the country, teacher-librarians are losing their jobs or being reassigned. Collections are becoming depleted owing to budget cuts. Some principals believe that in the age of the Internet and the classroom workstation, the school library is an artifact” (9. Within this context, school librarians are looking to our research literature for evidence of the impact that school library programs have on learning outcomes and student success. They are integrating that evidence into their practice, and reflecting upon what can be improved locally. They are focusing on students and showing the impact of school libraries and

  6. Public medical shows.

    Science.gov (United States)

    Walusinski, Olivier

    2014-01-01

    In the second half of the 19th century, Jean-Martin Charcot (1825-1893) became famous for the quality of his teaching and his innovative neurological discoveries, bringing many French and foreign students to Paris. A hunger for recognition, together with progressive and anticlerical ideals, led Charcot to invite writers, journalists, and politicians to his lessons, during which he presented the results of his work on hysteria. These events became public performances, for which physicians and patients were transformed into actors. Major newspapers ran accounts of these consultations, more like theatrical shows in some respects. The resultant enthusiasm prompted other physicians in Paris and throughout France to try and imitate them. We will compare the form and substance of Charcot's lessons with those given by Jules-Bernard Luys (1828-1897), Victor Dumontpallier (1826-1899), Ambroise-Auguste Liébault (1823-1904), Hippolyte Bernheim (1840-1919), Joseph Grasset (1849-1918), and Albert Pitres (1848-1928). We will also note their impact on contemporary cinema and theatre.

  7. The Great Cometary Show

    Science.gov (United States)

    2007-01-01

    its high spatial and spectral resolution, it was possible to zoom into the very heart of this very massive star. In this innermost region, the observations are dominated by the extremely dense stellar wind that totally obscures the underlying central star. The AMBER observations show that this dense stellar wind is not spherically symmetric, but exhibits a clearly elongated structure. Overall, the AMBER observations confirm that the extremely high mass loss of Eta Carinae's massive central star is non-spherical and much stronger along the poles than in the equatorial plane. This is in agreement with theoretical models that predict such an enhanced polar mass-loss in the case of rapidly rotating stars. ESO PR Photo 06c/07 ESO PR Photo 06c/07 RS Ophiuchi in Outburst Several papers from this special feature focus on the later stages in a star's life. One looks at the binary system Gamma 2 Velorum, which contains the closest example of a star known as a Wolf-Rayet. A single AMBER observation allowed the astronomers to separate the spectra of the two components, offering new insights in the modeling of Wolf-Rayet stars, but made it also possible to measure the separation between the two stars. This led to a new determination of the distance of the system, showing that previous estimates were incorrect. The observations also revealed information on the region where the winds from the two stars collide. The famous binary system RS Ophiuchi, an example of a recurrent nova, was observed just 5 days after it was discovered to be in outburst on 12 February 2006, an event that has been expected for 21 years. AMBER was able to detect the extension of the expanding nova emission. These observations show a complex geometry and kinematics, far from the simple interpretation of a spherical fireball in extension. AMBER has detected a high velocity jet probably perpendicular to the orbital plane of the binary system, and allowed a precise and careful study of the wind and the shockwave

  8. On Preliminary Breakdown

    Science.gov (United States)

    Beasley, W. H.; Petersen, D.

    2013-12-01

    The preliminary breakdown phase of a negative cloud-to-ground lightning flash was observed in detail. Observations were made with a Photron SA1.1 high-speed video camera operating at 9,000 frames per second, fast optical sensors, a flat-plate electric field antenna covering the SLF to MF band, and VHF and UHF radio receivers with bandwidths of 20 MHz. Bright stepwise extensions of a negative leader were observed at an altitude of 8 km during the first few milliseconds of the flash, and were coincident with bipolar electric field pulses called 'characteristic pulses'. The 2-D step lengths of the preliminary processes were in excess of 100 meters, with some 2-D step lengths in excess of 200 meters. Smaller and shorter unipolar electric field pulses were superposed onto the bipolar electric field pulses, and were coincident with VHF and UHF radio pulses. After a few milliseconds, the emerging negative stepped leader system showed a marked decrease in luminosity, step length, and propagation velocity. Details of these events will be discussed, including the possibility that the preliminary breakdown phase consists not of a single developing lightning leader system, but of multiple smaller lightning leader systems that eventually join together into a single system.

  9. Preliminary Multiphysics Analyses of HFIR LEU Fuel Conversion using COMSOL

    Energy Technology Data Exchange (ETDEWEB)

    Freels, James D [ORNL; Bodey, Isaac T [ORNL; Arimilli, Rao V [ORNL; Curtis, Franklin G [ORNL; Ekici, Kivanc [ORNL; Jain, Prashant K [ORNL

    2011-06-01

    The research documented herein was performed by several individuals across multiple organizations. We have previously acknowledged our funding for the project, but another common thread among the authors of this document, and hence the research performed, is the analysis tool COMSOL. The research has been divided into categories to allow the COMSOL analysis to be performed independently to the extent possible. As will be seen herein, the research has progressed to the point where it is expected that next year (2011) a large fraction of the research will require collaboration of our efforts as we progress almost exclusively into three-dimensional (3D) analysis. To the extent possible, we have tried to segregate the development effort into two-dimensional (2D) analysis in order to arrive at techniques and methodology that can be extended to 3D models in a timely manner. The Research Reactors Division (RRD) of ORNL has contracted with the University of Tennessee, Knoxville (UTK) Mechanical, Aerospace and Biomedical Engineering Department (MABE) to perform a significant fraction of this research. This group has been chosen due to their expertise and long-term commitment in using COMSOL and also because the participating students are able to work onsite on a part-time basis due to the close proximity of UTK with the ORNL campus. The UTK research has been governed by a statement of work (SOW) which clearly defines the specific tasks reported herein on the perspective areas of research. Ph.D. student Isaac T. Bodey has focused on heat transfer, fluid flow, modeling, and meshing issues and has been aided by his major professor Dr. Rao V. Arimilli and is the primary contributor to Section 2 of this report. Ph.D student Franklin G. Curtis has been focusing exclusively on fluid-structure interaction (FSI) due to the mechanical forces acting on the plate caused by the flow and has also been aided by his major professor Dr. Kivanc Ekici and is the primary contributor to Section 4 of this report. The HFIR LEU conversion project has also obtained the services of Dr. Prashant K. Jain of the Reactor & Nuclear Systems Division (RNSD) of ORNL. Prashant has quickly adapted to the COMSOL tools and has been focusing on thermal-structure interaction (TSI) issues and development of alternative 3D model approaches that could yield faster-running solutions. Prashant is the primary contributor to Section 5 of the report. And finally, while incorporating findings from all members of the COMSOL team (i.e., the team) and contributing as the senior COMSOL leader and advocate, Dr. James D. Freels has focused on the 3D model development, cluster deployment, and has contributed primarily to Section 3 and overall integration of this report. The team has migrated to the current release of COMSOL at version 4.1 for all the work described in this report, except where stated otherwise. Just as in the performance of the research, each of the respective sections has been originally authored by the respective authors. Therefore, the reader will observe a contrast in writing style throughout this document.

  10. Fluctuations of Lake Orta water levels: preliminary analyses

    Directory of Open Access Journals (Sweden)

    Helmi Saidi

    2016-04-01

    Full Text Available While the effects of past industrial pollution on the chemistry and biology of Lake Orta have been well documented, annual and seasonal fluctuations of lake levels have not yet been studied. Considering their potential impacts on both the ecosystem and on human safety, fluctuations in lake levels are an important aspect of limnological research. In the enormous catchment of Lake Maggiore, there are many rivers and lakes, and the amount of annual precipitation is both high and concentrated in spring and autumn. This has produced major flood events, most recently in November 2014. Flood events are also frequent on Lake Orta, occurring roughly triennially since 1917. The 1926, 1951, 1976 and 2014 floods were severe, with lake levels raised from 2.30 m to 3.46 m above the hydrometric zero. The most important event occurred in 1976, with a maximum level equal to 292.31 m asl and a return period of 147 years. In 2014 the lake level reached 291.89 m asl and its return period was 54 years. In this study, we defined trends and temporal fluctuations in Lake Orta water levels from 1917 to 2014, focusing on extremes. We report both annual maximum and seasonal variations of the lake water levels over this period. Both Mann-Kendall trend tests and simple linear regression were utilized to detect monotonic trends in annual and seasonal extremes, and logistic regression was used to detect trends in the number of flood events. Lake level decreased during winter and summer seasons, and a small but statistically non-significant positive trend was found in the number of flood events over the period. We provide estimations of return period for lake levels, a metric which could be used in planning lake flood protection measures.

  11. HPLC-MS/MS analyses show that the near-Starchless aps1 and pgm leaves accumulate wild type levels of ADPglucose: further evidence for the occurrence of important ADPglucose biosynthetic pathway(s alternative to the pPGI-pPGM-AGP pathway.

    Directory of Open Access Journals (Sweden)

    Abdellatif Bahaji

    Full Text Available In leaves, it is widely assumed that starch is the end-product of a metabolic pathway exclusively taking place in the chloroplast that (a involves plastidic phosphoglucomutase (pPGM, ADPglucose (ADPG pyrophosphorylase (AGP and starch synthase (SS, and (b is linked to the Calvin-Benson cycle by means of the plastidic phosphoglucose isomerase (pPGI. This view also implies that AGP is the sole enzyme producing the starch precursor molecule, ADPG. However, mounting evidence has been compiled pointing to the occurrence of important sources, other than the pPGI-pPGM-AGP pathway, of ADPG. To further explore this possibility, in this work two independent laboratories have carried out HPLC-MS/MS analyses of ADPG content in leaves of the near-starchless pgm and aps1 mutants impaired in pPGM and AGP, respectively, and in leaves of double aps1/pgm mutants grown under two different culture conditions. We also measured the ADPG content in wild type (WT and aps1 leaves expressing in the plastid two different ADPG cleaving enzymes, and in aps1 leaves expressing in the plastid GlgC, a bacterial AGP. Furthermore, we measured the ADPG content in ss3/ss4/aps1 mutants impaired in starch granule initiation and chloroplastic ADPG synthesis. We found that, irrespective of their starch contents, pgm and aps1 leaves, WT and aps1 leaves expressing in the plastid ADPG cleaving enzymes, and aps1 leaves expressing in the plastid GlgC accumulate WT ADPG content. In clear contrast, ss3/ss4/aps1 leaves accumulated ca. 300 fold-more ADPG than WT leaves. The overall data showed that, in Arabidopsis leaves, (a there are important ADPG biosynthetic pathways, other than the pPGI-pPGM-AGP pathway, (b pPGM and AGP are not major determinants of intracellular ADPG content, and (c the contribution of the chloroplastic ADPG pool to the total ADPG pool is low.

  12. THE EFFECTS OF PRELIMINARY RULINGS

    Directory of Open Access Journals (Sweden)

    Iuliana-Mădălina LARION

    2015-07-01

    Full Text Available The study analyses the effects of the preliminary rulings rendered by the Court of Justice for the judicial body that made the reference and for other bodies dealing with similar cases, for the member states, for the European Union’ s institutions and for EU legal order. Starting from the binding effect of the preliminary judgment for national judicial bodies, which requires them to follow the ruling or make a new reference, to the lack of precedent doctrine in EU law, continuing with the possibility to indirectly verify the compatibility of national law of the member states with EU law and ending with the administrative or legislative measures that can or must be taken by the member states, the study intends to highlight the limits, nuances and consequences of the binding effect. It mentions the contribution of the national courts and of the Court of Justice of the European Union to the development of EU law, such as clarifying autonomous notions and it emphasizes the preliminary procedure's attributes of being a form of judicial protection of individual rights, as well as a means to review the legality of acts of EU institutions. The paper is meant to be a useful instrument for practitioners. Therefor, it also deals with the possibility and limits of asking new questions, in order to obtain reconsideration or a refinement of the legal issue and with the problem of judicial control over the interpretation and application of the preliminary ruling by the lower court.

  13. Preliminary Monthly Climatological Summaries

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Preliminary Local Climatological Data, recorded since 1970 on Weather Burean Form 1030 and then National Weather Service Form F-6. The preliminary climate data pages...

  14. 14 CFR 314.14 - Show-cause order.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Show-cause order. 314.14 Section 314.14... REGULATIONS EMPLOYEE PROTECTION PROGRAM Determination of Qualifying Dislocation § 314.14 Show-cause order. When the Department makes a preliminary determination of whether the major cause of the bankruptcy...

  15. Preliminary ECLSS waste water model

    Science.gov (United States)

    Carter, Donald L.; Holder, Donald W., Jr.; Alexander, Kevin; Shaw, R. G.; Hayase, John K.

    1991-01-01

    A preliminary waste water model for input to the Space Station Freedom (SSF) Environmental Control and Life Support System (ECLSS) Water Processor (WP) has been generated for design purposes. Data have been compiled from various ECLSS tests and flight sample analyses. A discussion of the characterization of the waste streams comprising the model is presented, along with a discussion of the waste water model and the rationale for the inclusion of contaminants in their respective concentrations. The major objective is to establish a methodology for the development of a waste water model and to present the current state of that model.

  16. Preliminary ECLSS waste water model

    Science.gov (United States)

    Carter, Donald L.; Holder, Donald W., Jr.; Alexander, Kevin; Shaw, R. G.; Hayase, John K.

    1991-01-01

    A preliminary waste water model for input to the Space Station Freedom (SSF) Environmental Control and Life Support System (ECLSS) Water Processor (WP) has been generated for design purposes. Data have been compiled from various ECLSS tests and flight sample analyses. A discussion of the characterization of the waste streams comprising the model is presented, along with a discussion of the waste water model and the rationale for the inclusion of contaminants in their respective concentrations. The major objective is to establish a methodology for the development of a waste water model and to present the current state of that model.

  17. Network class superposition analyses.

    Directory of Open Access Journals (Sweden)

    Carl A B Pearson

    Full Text Available Networks are often used to understand a whole system by modeling the interactions among its pieces. Examples include biomolecules in a cell interacting to provide some primary function, or species in an environment forming a stable community. However, these interactions are often unknown; instead, the pieces' dynamic states are known, and network structure must be inferred. Because observed function may be explained by many different networks (e.g., ≈ 10(30 for the yeast cell cycle process, considering dynamics beyond this primary function means picking a single network or suitable sample: measuring over all networks exhibiting the primary function is computationally infeasible. We circumvent that obstacle by calculating the network class ensemble. We represent the ensemble by a stochastic matrix T, which is a transition-by-transition superposition of the system dynamics for each member of the class. We present concrete results for T derived from boolean time series dynamics on networks obeying the Strong Inhibition rule, by applying T to several traditional questions about network dynamics. We show that the distribution of the number of point attractors can be accurately estimated with T. We show how to generate Derrida plots based on T. We show that T-based Shannon entropy outperforms other methods at selecting experiments to further narrow the network structure. We also outline an experimental test of predictions based on T. We motivate all of these results in terms of a popular molecular biology boolean network model for the yeast cell cycle, but the methods and analyses we introduce are general. We conclude with open questions for T, for example, application to other models, computational considerations when scaling up to larger systems, and other potential analyses.

  18. The Nullness Analyser of julia

    Science.gov (United States)

    Spoto, Fausto

    This experimental paper describes the implementation and evaluation of a static nullness analyser for single-threaded Java and Java bytecode programs, built inside the julia tool. Nullness analysis determines, at compile-time, those program points where the null value might be dereferenced, leading to a run-time exception. In order to improve the quality of software, it is important to prove that such situation does not occur. Our analyser is based on a denotational abstract interpretation of Java bytecode through Boolean logical formulas, strengthened with a set of denotational and constraint-based supporting analyses for locally non-null fields and full arrays and collections. The complete integration of all such analyses results in a correct system of very high precision whose time of analysis remains in the order of minutes, as we show with some examples of analysis of large software.

  19. Sproglig Metode og Analyse

    DEFF Research Database (Denmark)

    le Fevre Jakobsen, Bjarne

    Publikationen indeholder øvematerialer, tekster, powerpointpræsentationer og handouts til undervisningsfaget Sproglig Metode og Analyse på BA og tilvalg i Dansk/Nordisk 2010-2011......Publikationen indeholder øvematerialer, tekster, powerpointpræsentationer og handouts til undervisningsfaget Sproglig Metode og Analyse på BA og tilvalg i Dansk/Nordisk 2010-2011...

  20. 2016 TRI Preliminary Dataset

    Science.gov (United States)

    The TRI preliminary dataset includes the most current TRI data available and reflects toxic chemical releases and pollution prevention activities that occurred at TRI facilities during the 2016 calendar year.

  1. Preliminary reference Earth model

    Science.gov (United States)

    Dziewonski, Adam M.; Anderson, Don L.

    1981-06-01

    A large data set consisting of about 1000 normal mode periods, 500 summary travel time observations, 100 normal mode Q values, mass and moment of inertia have been inverted to obtain the radial distribution of elastic properties, Q values and density in the Earth's interior. The data set was supplemented with a special study of 12 years of ISC phase data which yielded an additional 1.75 × 10 6 travel time observations for P and S waves. In order to obtain satisfactory agreement with the entire data set we were required to take into account anelastic dispersion. The introduction of transverse isotropy into the outer 220 km of the mantle was required in order to satisfy the shorter period fundamental toroidal and spheroidal modes. This anisotropy also improved the fit of the larger data set. The horizontal and vertical velocities in the upper mantle differ by 2-4%, both for P and S waves. The mantle below 220 km is not required to be anisotropic. Mantle Rayleigh waves are surprisingly sensitive to compressional velocity in the upper mantle. High S n velocities, low P n velocities and a pronounced low-velocity zone are features of most global inversion models that are suppressed when anisotropy is allowed for in the inversion. The Preliminary Reference Earth Model, PREM, and auxiliary tables showing fits to the data are presented.

  2. Planning a Successful Tech Show

    Science.gov (United States)

    Nikirk, Martin

    2011-01-01

    Tech shows are a great way to introduce prospective students, parents, and local business and industry to a technology and engineering or career and technical education program. In addition to showcasing instructional programs, a tech show allows students to demonstrate their professionalism and skills, practice public presentations, and interact…

  3. Genomic analyses of musashi1 downstream targets show a strong association with cancer-related processes.

    Science.gov (United States)

    de Sousa Abreu, Raquel; Sanchez-Diaz, Patricia C; Vogel, Christine; Burns, Suzanne C; Ko, Daijin; Burton, Tarea L; Vo, Dat T; Chennasamudaram, Soudhamini; Le, Shu-Yun; Shapiro, Bruce A; Penalva, Luiz O F

    2009-05-01

    Musashi1 (Msi1) is a highly conserved RNA-binding protein with pivotal functions in stem cell maintenance, nervous system development, and tumorigenesis. Despite its importance, only three direct mRNA targets have been characterized so far: m-numb, CDKN1A, and c-mos. Msi1 has been shown to affect their translation by binding to short elements located in the 3'-untranslated region. To better understand Msi1 functions, we initially performed an RIP-Chip analysis in HEK293T cells; this method consists of isolation of specific RNA-protein complexes followed by identification of the RNA component via microarrays. A group of 64 mRNAs was found to be enriched in the Msi1-associated population compared with controls. These genes belong to two main functional categories pertinent to tumorigenesis: 1) cell cycle, cell proliferation, cell differentiation, and apoptosis and 2) protein modification (including ubiquitination and ubiquitin cycle). To corroborate our findings, we examined the impact of Msi1 expression on both mRNA (transcriptomic) and protein (proteomic) expression levels. Genes whose mRNA levels were affected by Msi1 expression have a Gene Ontology distribution similar to RIP-Chip results, reinforcing Msi1 participation in cancer-related processes. The proteomics study revealed that Msi1 can have either positive or negative effects on gene expression of its direct targets. In summary, our results indicate that Msi1 affects a network of genes and could function as a master regulator during development and tumor formation.

  4. Measuring performance at trade shows

    DEFF Research Database (Denmark)

    Hansen, Kåre

    2004-01-01

    Trade shows is an increasingly important marketing activity to many companies, but current measures of trade show performance do not adequately capture dimensions important to exhibitors. Based on the marketing literature's outcome and behavior-based control system taxonomy, a model is built...... that captures a outcome-based sales dimension and four behavior-based dimensions (i.e. information-gathering, relationship building, image building, and motivation activities). A 16-item instrument is developed for assessing exhibitors perceptions of their trade show performance. The paper presents evidence...

  5. Tokyo Motor Show 2003; Tokyo Motor Show 2003

    Energy Technology Data Exchange (ETDEWEB)

    Joly, E.

    2004-01-01

    The text which follows present the different techniques exposed during the 37. Tokyo Motor Show. The report points out the great tendencies of developments of the Japanese automobile industry. The hybrid electric-powered vehicles or those equipped with fuel cells have been highlighted by the Japanese manufacturers which allow considerable budgets in the research of less polluting vehicles. The exposed models, although being all different according to the manufacturer, use always a hybrid system: fuel cell/battery. The manufacturers have stressed too on the intelligent systems for navigation and safety as well as on the design and comfort. (O.M.)

  6. Phyllodes tumor showing intraductal growth.

    Science.gov (United States)

    Makidono, Akari; Tsunoda, Hiroko; Mori, Miki; Yagata, Hiroshi; Onoda, Yui; Kikuchi, Mari; Nozaki, Taiki; Saida, Yukihisa; Nakamura, Seigo; Suzuki, Koyu

    2013-07-01

    Phyllodes tumor of the breast is a rare fibroepithelial lesion and particularly uncommon in adolescent girls. It is thought to arise from the periductal rather than intralobular stroma. Usually, it is seen as a well-defined mass. Phyllodes tumor showing intraductal growth is extremely rare. Here we report a girl who has a phyllodes tumor with intraductal growth.

  7. Pembrolizumab Shows Promise for NSCLC.

    Science.gov (United States)

    2015-06-01

    Data from the KEYNOTE-001 trial show that pembrolizumab improves clinical outcomes for patients with advanced non-small cell lung cancer, and is well tolerated. PD-L1 expression in at least 50% of tumor cells correlated with improved efficacy.

  8. Create a Polarized Light Show.

    Science.gov (United States)

    Conrad, William H.

    1992-01-01

    Presents a lesson that introduces students to polarized light using a problem-solving approach. After illustrating the concept using a slinky and poster board with a vertical slot, students solve the problem of creating a polarized light show using Polya's problem-solving methods. (MDH)

  9. Quantifying show jumping horse rider expertise using IMUs.

    Science.gov (United States)

    Patterson, M; Doyle, J; Cahill, E; Caulfield, B; McCarthy Persson, U

    2010-01-01

    Horse rider ability has long been measured using horse performance, competition results and visual observation. Scientific methods of measuring rider ability on the flat are emerging such as measuring position angles and harmony of the horse-rider system. To date no research has quantified rider ability in show jumping. Kinematic analysis and motion sensors have been used in sports other than show jumping to measure the quality of motor control patterns in humans. The aim of this study was to quantify rider ability in show jumping using body-mounted IMUs. Preliminary results indicate that there are clear differences in experienced and novice riders during show jumping.

  10. Reality show: um paradoxo nietzschiano

    Directory of Open Access Journals (Sweden)

    Ilana Feldman

    2011-01-01

    Full Text Available

    O fenômeno dos reality shows - e a subseqüente relação entre imagem e verdade - assenta-se sobre uma série de paradoxos. Tais paradoxos podem ser compreendidos à luz do pensamento do filósofo alemão Friedrich Nietzsche, que, através dos usos de formulações paradoxais, concebia a realidade como um mundo de pura aparência e a verdade como um acréscimo ficcional, como um efeito. A ficção é então tomada, na filosofia de Nietzsche, não em seu aspecto falsificante e desrealizador - como sempre pleiteou nossa tradição metafísica -, mas como condição necessária para que certa espécie de invenção possa operar como verdade. Sendo assim, a própria expressão reality show, através de sua formulação paradoxal, engendra explicitamente um mundo de pura aparência, em que a verdade, a parte reality da proposição, é da ordem do suplemento, daquilo que se acrescenta ficcionalmente - como um adjetivo - a show. O ornamento, nesse caso, passa a ocupar o lugar central, apontando para o efeito produzido: o efeito-de-verdade. Seguindo, então, o pensamento nietzschiano e sua atualização na contemporaneidade, investigaremos de que forma os televisivos “shows de realidade” operam paradoxalmente, em consonância com nossas paradoxais práticas culturais.

  11. Preliminary considerations concerning actinide solubilities

    Energy Technology Data Exchange (ETDEWEB)

    Newton, T.W.; Bayhurst, B.P.; Daniels, W.R.; Erdal, B.R.; Ogard, A.E.

    1980-01-01

    Work at the Los Alamos Scientific Laboratory on the fundamental solution chemistry of the actinides has thus far been confined to preliminary considerations of the problems involved in developing an understanding of the precipitation and dissolution behavior of actinide compounds under environmental conditions. Attempts have been made to calculate solubility as a function of Eh and pH using the appropriate thermodynamic data; results have been presented in terms of contour maps showing lines of constant solubility as a function of Eh and pH. Possible methods of control of the redox potential of rock-groundwater systems by the use of Eh buffers (redox couples) is presented.

  12. Laser Beam Focus Analyser

    DEFF Research Database (Denmark)

    Nielsen, Peter Carøe; Hansen, Hans Nørgaard; Olsen, Flemming Ove

    2007-01-01

    The quantitative and qualitative description of laser beam characteristics is important for process implementation and optimisation. In particular, a need for quantitative characterisation of beam diameter was identified when using fibre lasers for micro manufacturing. Here the beam diameter limits...... the obtainable features in direct laser machining as well as heat affected zones in welding processes. This paper describes the development of a measuring unit capable of analysing beam shape and diameter of lasers to be used in manufacturing processes. The analyser is based on the principle of a rotating...... mechanical wire being swept through the laser beam at varying Z-heights. The reflected signal is analysed and the resulting beam profile determined. The development comprised the design of a flexible fixture capable of providing both rotation and Z-axis movement, control software including data capture...

  13. Picasso on Show in Shanghai

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    A staff member of the National Picasso Museum of France checks one of the great Spanish artist Pablo Picasso’s works at the China Pavilion inside the site of the 2010 World Expo in Shanghai on October 12.Sixty-two priceless paintings and statues selected from the works of the renowned artist have been brought to the pavilion for an upcoming exhibition to premiere on October 18.Besides these representative masterpieces,50 valuable photographs showing the artist’s whole life will also be presented.The exhibition’s estimated value is 678 million euros ($934 million).It will be held until January 10,2012.

  14. Reality shows: uma abordagem psicossocial

    Directory of Open Access Journals (Sweden)

    Marília Pereira Bueno Millan

    Full Text Available Desde os primórdios da civilização, o ser humano mostra necessidade de representar cenicamente seus dramas pessoais e vicissitudes existenciais. O "reality show" é uma das versões pós-modernas da encenação da vida humana. Este artigo, por meio de uma pesquisa bibliográfica, analisa criticamente as relações existentes entre o "reality show" e aspectos psicossociais do comportamento humano. Conclui-se que tais programas televisivos são o retrato da contemporaneidade, ou seja, revelam a morte do sujeito, a fugacidade das experiências vividas, a desvalorização da história e o culto à imagem e à superficialidade. Por meio da sedução do espectador, mobilizam-se aspectos primitivos de seu psiquismo, fazendo com que ele se sinta narcisicamente poderoso e onipotente e se acredite dono do destino dos participantes do programa. Sugerem-se novos estudos que contribuam para a reflexão crítica e maior conscientização.

  15. "Medicine show." Alice in Doctorland.

    Science.gov (United States)

    1987-01-01

    This is an excerpt from the script of a 1939 play provided to the Institute of Social Medicine and Community Health by the Library of Congress Federal Theater Project Collection at George Mason University Library, Fairfax, Virginia, pages 2-1-8 thru 2-1-14. The Federal Theatre Project (FTP) was part of the New Deal program for the arts 1935-1939. Funded by the Works Progress Administration (WPA) its goal was to employ theater professionals from the relief rolls. A number of FTP plays deal with aspects of medicine and public health. Pageants, puppet shows and documentary plays celebrated progress in medical science while examining social controversies in medical services and the public health movement. "Medicine Show" sharply contrasts technological wonders with social backwardness. The play was rehearsed by the FTP but never opened because funding ended. A revised version ran on Broadway in 1940. The preceding comments are adapted from an excellent, well-illustrated review of five of these plays by Barabara Melosh: "The New Deal's Federal Theatre Project," Medical Heritage, Vol. 2, No. 1 (Jan/Feb 1986), pp. 36-47.

  16. UVISS preliminary visibility analysis

    DEFF Research Database (Denmark)

    Betto, Maurizio

    1998-01-01

    The goal of this work is to obtain a preliminary assessment of the sky visibility for anastronomical telescope located on the express pallet of the International SpaceStation (ISS)} taking into account the major constraints imposed on the instrument by the ISSattitude and structure. Part of the w......The goal of this work is to obtain a preliminary assessment of the sky visibility for anastronomical telescope located on the express pallet of the International SpaceStation (ISS)} taking into account the major constraints imposed on the instrument by the ISSattitude and structure. Part...

  17. Meta-analyses

    NARCIS (Netherlands)

    Hendriks, M.A.; Luyten, J.W.; Scheerens, J.; Sleegers, P.J.C.; Scheerens, J.

    2014-01-01

    In this chapter results of a research synthesis and quantitative meta-analyses of three facets of time effects in education are presented, namely time at school during regular lesson hours, homework, and extended learning time. The number of studies for these three facets of time that could be used

  18. Contesting Citizenship: Comparative Analyses

    DEFF Research Database (Denmark)

    Siim, Birte; Squires, Judith

    2007-01-01

    . Comparative citizenship analyses need to be considered in relation to multipleinequalities and their intersections and to multiple governance and trans-national organisinf. This, in turn, suggests that comparative citizenship analysis needs to consider new spaces in which struggles for equal citizenship occur...

  19. Wavelet Analyses and Applications

    Science.gov (United States)

    Bordeianu, Cristian C.; Landau, Rubin H.; Paez, Manuel J.

    2009-01-01

    It is shown how a modern extension of Fourier analysis known as wavelet analysis is applied to signals containing multiscale information. First, a continuous wavelet transform is used to analyse the spectrum of a nonstationary signal (one whose form changes in time). The spectral analysis of such a signal gives the strength of the signal in each…

  20. Report sensory analyses veal

    NARCIS (Netherlands)

    Veldman, M.; Schelvis-Smit, A.A.M.

    2005-01-01

    On behalf of a client of Animal Sciences Group, different varieties of veal were analyzed by both instrumental and sensory analyses. The sensory evaluation was performed with a sensory analytical panel in the period of 13th of May and 31st of May, 2005. The three varieties of veal were: young bull,

  1. Casimir experiments showing saturation effects

    CERN Document Server

    Sernelius, Bo E

    2009-01-01

    We address several different Casimir experiments where theory and experiment disagree. First out is the classical Casimir force measurement between two metal half spaces; here both in the form of the torsion pendulum experiment by Lamoreaux and in the form of the Casimir pressure measurement between a gold sphere and a gold plate as performed by Decca et al.; theory predicts a large negative thermal correction, absent in the high precision experiments. The third experiment is the measurement of the Casimir force between a metal plate and a laser irradiated semiconductor membrane as performed by Chen et al.; the change in force with laser intensity is larger than predicted by theory. The fourth experiment is the measurement of the Casimir force between an atom and a wall in the form of the measurement by Obrecht et al. of the change in oscillation frequency of a 87 Rb Bose-Einstein condensate trapped to a fused silica wall; the change is smaller than predicted by theory. We show that saturation effects can exp...

  2. UVISS preliminary visibility analysis

    DEFF Research Database (Denmark)

    Betto, Maurizio

    1998-01-01

    The goal of this work is to obtain a preliminary assessment of the sky visibility for anastronomical telescope located on the express pallet of the International SpaceStation (ISS)} taking into account the major constraints imposed on the instrument by the ISSattitude and structure. Part...

  3. Preliminary Investigation of a Paraglider

    Science.gov (United States)

    Rogallo, Francis M.; Lowry, John G.; Croom, Delwin R.; Taylor, Robert T.

    1960-01-01

    A preliminary investigation of the aerodynamic and control characteristics of a flexible glider similar to a parachute in construction has been made at the Langley Research Center to evaluate its capabilities as a reentry glider. Preliminary weight estimates of the proposed vehicle indicate that such a structure can be made with extremely low wing loading. Maximum temperatures during the reentry maneuver might be held as low as about 1,500 F. The results of wind-tunnel and free-glide tests show that the glider when constructed of nonporous material performed extremely well at subsonic speeds and could be flown at angles of attack from about 200 to 900. At supersonic speeds the wing showed none of the unfavorable tendencies exhibited by conventional parachutes at these speeds, such as squidding and breathing. Several methods of packing and deploying the glider have been successfully demonstrated. The results of this study indicate that this flexible-lifting-surface concept may provide a lightweight controllable paraglider for manned space vehicles.

  4. Possible future HERA analyses

    CERN Document Server

    Geiser, Achim

    2015-01-01

    A variety of possible future analyses of HERA data in the context of the HERA data preservation programme is collected, motivated, and commented. The focus is placed on possible future analyses of the existing $ep$ collider data and their physics scope. Comparisons to the original scope of the HERA programme are made, and cross references to topics also covered by other participants of the workshop are given. This includes topics on QCD, proton structure, diffraction, jets, hadronic final states, heavy flavours, electroweak physics, and the application of related theory and phenomenology topics like NNLO QCD calculations, low-x related models, nonperturbative QCD aspects, and electroweak radiative corrections. Synergies with other collider programmes are also addressed. In summary, the range of physics topics which can still be uniquely covered using the existing data is very broad and of considerable physics interest, often matching the interest of results from colliders currently in operation. Due to well-e...

  5. Analysing Access Control Specifications

    DEFF Research Database (Denmark)

    Probst, Christian W.; Hansen, René Rydhof

    2009-01-01

    . Recent events have revealed intimate knowledge of surveillance and control systems on the side of the attacker, making it often impossible to deduce the identity of an inside attacker from logged data. In this work we present an approach that analyses the access control configuration to identify the set......When prosecuting crimes, the main question to answer is often who had a motive and the possibility to commit the crime. When investigating cyber crimes, the question of possibility is often hard to answer, as in a networked system almost any location can be accessed from almost anywhere. The most...... of credentials needed to reach a certain location in a system. This knowledge allows to identify a set of (inside) actors who have the possibility to commit an insider attack at that location. This has immediate applications in analysing log files, but also nontechnical applications such as identifying possible...

  6. Preliminary studies of a new accelerator-driven minor actinide burner in industrial scale

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xunzhao; Zhou, Shengcheng [School of Nuclear Science and Technology, Xi’an Jiaotong University, Xi’an 710049, Shaanxi (China); Zheng, Youqi, E-mail: yqzheng@mail.xjtu.edu.cn [School of Nuclear Science and Technology, Xi’an Jiaotong University, Xi’an 710049, Shaanxi (China); Wang, Kunpeng [Nuclear and Radiation Safety Center, PO Box 8088, No. 54, Beijing 100082 (China); Wu, Hongchun [School of Nuclear Science and Technology, Xi’an Jiaotong University, Xi’an 710049, Shaanxi (China)

    2015-10-15

    Highlights: • A new accelerator-driven minor actinide (MA) burner was proposed. • Comprehensive design of spallation target, fuel assembly and subcritical core was performed. • Preliminary safety analyses indicate the inherent safety of the core in the reactivity insertion (500 pcm) and beam overpower (50% increase) transients. - Abstract: Pursuing high transmutation rate of minor actinide (MA), a preliminary conceptual design of a lead-bismuth (LBE) cooled accelerator-driven system (ADS) is proposed in this study. Parametric studies are performed to optimize the neutronics and thermal–hydraulics performances. The proton energy and axial position of the proton beam impact is investigated to obtain high neutron source efficiency and spallation neutron yield. The influences of MA/Pu mixing ratio and the ratio of pin pitch to diameter (P/D) are also optimized to control the burnup reactivity swing and the minimum coolant velocity for adequate cooling. To reduce the power peak, three kinds of power flattening techniques are adopted and compared. The results show that the inert matrix ratio zone loading method seems more versatile. Based on the analyses, an optimized three zone loading pattern is proposed for the 800 MWth subcritical core. The total transmutation rate of MA is 328.8 kg per effective full power year. Preliminary safety analyses based on the balance of power method (BOP) are performed and the results show that in the reactivity insertion and beam overpower transients, the core shows inherent safety, but the scram is necessary by cutting off the beam current to protect the core from possible damages caused by the loss of flow.

  7. Biomass feedstock analyses

    Energy Technology Data Exchange (ETDEWEB)

    Wilen, C.; Moilanen, A.; Kurkela, E. [VTT Energy, Espoo (Finland). Energy Production Technologies

    1996-12-31

    The overall objectives of the project `Feasibility of electricity production from biomass by pressurized gasification systems` within the EC Research Programme JOULE II were to evaluate the potential of advanced power production systems based on biomass gasification and to study the technical and economic feasibility of these new processes with different type of biomass feed stocks. This report was prepared as part of this R and D project. The objectives of this task were to perform fuel analyses of potential woody and herbaceous biomasses with specific regard to the gasification properties of the selected feed stocks. The analyses of 15 Scandinavian and European biomass feed stock included density, proximate and ultimate analyses, trace compounds, ash composition and fusion behaviour in oxidizing and reducing atmospheres. The wood-derived fuels, such as whole-tree chips, forest residues, bark and to some extent willow, can be expected to have good gasification properties. Difficulties caused by ash fusion and sintering in straw combustion and gasification are generally known. The ash and alkali metal contents of the European biomasses harvested in Italy resembled those of the Nordic straws, and it is expected that they behave to a great extent as straw in gasification. Any direct relation between the ash fusion behavior (determined according to the standard method) and, for instance, the alkali metal content was not found in the laboratory determinations. A more profound characterisation of the fuels would require gasification experiments in a thermobalance and a PDU (Process development Unit) rig. (orig.) (10 refs.)

  8. Possible future HERA analyses

    Energy Technology Data Exchange (ETDEWEB)

    Geiser, Achim

    2015-12-15

    A variety of possible future analyses of HERA data in the context of the HERA data preservation programme is collected, motivated, and commented. The focus is placed on possible future analyses of the existing ep collider data and their physics scope. Comparisons to the original scope of the HERA pro- gramme are made, and cross references to topics also covered by other participants of the workshop are given. This includes topics on QCD, proton structure, diffraction, jets, hadronic final states, heavy flavours, electroweak physics, and the application of related theory and phenomenology topics like NNLO QCD calculations, low-x related models, nonperturbative QCD aspects, and electroweak radiative corrections. Synergies with other collider programmes are also addressed. In summary, the range of physics topics which can still be uniquely covered using the existing data is very broad and of considerable physics interest, often matching the interest of results from colliders currently in operation. Due to well-established data and MC sets, calibrations, and analysis procedures the manpower and expertise needed for a particular analysis is often very much smaller than that needed for an ongoing experiment. Since centrally funded manpower to carry out such analyses is not available any longer, this contribution not only targets experienced self-funded experimentalists, but also theorists and master-level students who might wish to carry out such an analysis.

  9. Preliminary Study on Airlift Membran—Bioreactor

    Institute of Scientific and Technical Information of China (English)

    XUNong; XINGWeihong; 等

    2002-01-01

    A new type of membrane bioreactor named “airlift membrane-bioreactor”is discussed.For municipal wastewater reclamation,the preliminary study on airlift membrane-bioreactor shows its good performance such as high flux and lower energy consumption.The airlift membrane-bioreactor is potentially applicable in bioengineering and environmental protection fields.

  10. Preliminary hazards analysis -- vitrification process

    Energy Technology Data Exchange (ETDEWEB)

    Coordes, D.; Ruggieri, M.; Russell, J.; TenBrook, W.; Yimbo, P. [Science Applications International Corp., Pleasanton, CA (United States)

    1994-06-01

    This paper presents a Preliminary Hazards Analysis (PHA) for mixed waste vitrification by joule heating. The purpose of performing a PHA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PHA is then followed by a Preliminary Safety Analysis Report (PSAR) performed during Title 1 and 2 design. The PSAR then leads to performance of the Final Safety Analysis Report performed during the facility`s construction and testing. It should be completed before routine operation of the facility commences. This PHA addresses the first four chapters of the safety analysis process, in accordance with the requirements of DOE Safety Guidelines in SG 830.110. The hazards associated with vitrification processes are evaluated using standard safety analysis methods which include: identification of credible potential hazardous energy sources; identification of preventative features of the facility or system; identification of mitigative features; and analyses of credible hazards. Maximal facility inventories of radioactive and hazardous materials are postulated to evaluate worst case accident consequences. These inventories were based on DOE-STD-1027-92 guidance and the surrogate waste streams defined by Mayberry, et al. Radiological assessments indicate that a facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous materials assessment indicates that a Mixed Waste Vitrification facility will be a Low Hazard facility having minimal impacts to offsite personnel and the environment.

  11. Multivariate Evolutionary Analyses in Astrophysics

    CERN Document Server

    Fraix-Burnet, Didier

    2011-01-01

    The large amount of data on galaxies, up to higher and higher redshifts, asks for sophisticated statistical approaches to build adequate classifications. Multivariate cluster analyses, that compare objects for their global similarities, are still confidential in astrophysics, probably because their results are somewhat difficult to interpret. We believe that the missing key is the unavoidable characteristics in our Universe: evolution. Our approach, known as Astrocladistics, is based on the evolutionary nature of both galaxies and their properties. It gathers objects according to their "histories" and establishes an evolutionary scenario among groups of objects. In this presentation, I show two recent results on globular clusters and earlytype galaxies to illustrate how the evolutionary concepts of Astrocladistics can also be useful for multivariate analyses such as K-means Cluster Analysis.

  12. Workload analyse of assembling process

    Science.gov (United States)

    Ghenghea, L. D.

    2015-11-01

    The workload is the most important indicator for managers responsible of industrial technological processes no matter if these are automated, mechanized or simply manual in each case, machines or workers will be in the focus of workload measurements. The paper deals with workload analyses made to a most part manual assembling technology for roller bearings assembling process, executed in a big company, with integrated bearings manufacturing processes. In this analyses the delay sample technique have been used to identify and divide all bearing assemblers activities, to get information about time parts from 480 minutes day work time that workers allow to each activity. The developed study shows some ways to increase the process productivity without supplementary investments and also indicated the process automation could be the solution to gain maximum productivity.

  13. AMS analyses at ANSTO

    Energy Technology Data Exchange (ETDEWEB)

    Lawson, E.M. [Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW (Australia). Physics Division

    1998-03-01

    The major use of ANTARES is Accelerator Mass Spectrometry (AMS) with {sup 14}C being the most commonly analysed radioisotope - presently about 35 % of the available beam time on ANTARES is used for {sup 14}C measurements. The accelerator measurements are supported by, and dependent on, a strong sample preparation section. The ANTARES AMS facility supports a wide range of investigations into fields such as global climate change, ice cores, oceanography, dendrochronology, anthropology, and classical and Australian archaeology. Described here are some examples of the ways in which AMS has been applied to support research into the archaeology, prehistory and culture of this continent`s indigenous Aboriginal peoples. (author)

  14. Analyse de "La banlieue"

    Directory of Open Access Journals (Sweden)

    Nelly Morais

    2006-11-01

    Full Text Available 1. Préambule - Conditions de réalisation de la présente analyse Un groupe d'étudiants de master 1 de FLE de l'université Paris 3 (donc des étudiants en didactique des langues se destinant à l'enseignement du FLE a observé le produit au cours d'un module sur les TIC (Technologies de l'Information et de la Communication et la didactique des langues. Une discussion s'est ensuite engagée sur le forum d'une plate-forme de formation à distance à partir de quelques questions posées par l'enseigna...

  15. EEG analyses with SOBI.

    Energy Technology Data Exchange (ETDEWEB)

    Glickman, Matthew R.; Tang, Akaysha (University of New Mexico, Albuquerque, NM)

    2009-02-01

    The motivating vision behind Sandia's MENTOR/PAL LDRD project has been that of systems which use real-time psychophysiological data to support and enhance human performance, both individually and of groups. Relevant and significant psychophysiological data being a necessary prerequisite to such systems, this LDRD has focused on identifying and refining such signals. The project has focused in particular on EEG (electroencephalogram) data as a promising candidate signal because it (potentially) provides a broad window on brain activity with relatively low cost and logistical constraints. We report here on two analyses performed on EEG data collected in this project using the SOBI (Second Order Blind Identification) algorithm to identify two independent sources of brain activity: one in the frontal lobe and one in the occipital. The first study looks at directional influences between the two components, while the second study looks at inferring gender based upon the frontal component.

  16. The show starts here: viewers’ interactions with recent television serials’ main title sequences

    Directory of Open Access Journals (Sweden)

    Annette Davison

    2013-12-01

    Full Text Available Recent title sequences for high production value television serials are generally one of two kinds: either extremely minimal, appearing part way through the episode with credits dispersed through the show, or as an extended format of c. ninety seconds’ duration, at or near the start of the show. In a previous book chapter I presented analyses of examples of the latter, arguing that the sequences form an efficient part of the brand image for both the show and commissioning channel. In order to explore the extent to which such sequences are watched or skipped by viewers, and how such decisions are made I organised a series of preliminary focus groups in February 2012 with participants who identified themselves as regular viewers of television serials, the findings of which are presented here. Two forms of stimuli were used: a main title sequence and an end credit sequence from a serial where different music is selected for this sequence for each episode. Analysis of the discussions indicates that the decision to view these sequences is dependent on a variety of factors. While for some the titles are required viewing, the participants in the groups are more likely to persistently view an end credit sequence where the music changes with the episode than an unchanging main title sequence. Perhaps most surprising, given the increase in opportunities for mobile viewing, is that for the participants of these groups television serials continue to be associated with social viewing in a domestic setting.

  17. Website-analyse

    DEFF Research Database (Denmark)

    Thorlacius, Lisbeth

    2009-01-01

    planlægning af de funktionelle og indholdsmæssige aspekter ved websites. Der findes en stor mængde teori- og metodebøger, som har specialiseret sig i de tekniske problemstillinger i forbindelse med interaktion og navigation, samt det sproglige indhold på websites. Den danske HCI (Human Computer Interaction...... hyperfunktionelle websites. Det primære ærinde for HCI-eksperterne er at udarbejde websites, som er brugervenlige. Ifølge deres direktiver skal websites være opbygget med hurtige og effektive navigations- og interaktionsstrukturer, hvor brugeren kan få sine informationer ubesværet af lange downloadingshastigheder...... eller blindgyder, når han/hun besøger sitet. Studier i design og analyse af de visuelle og æstetiske aspekter i planlægning og brug af websites har imidlertid kun i et begrænset omfang været under reflektorisk behandling. Det er baggrunden for dette kapitel, som indleder med en gennemgang af æstetikkens...

  18. Environmental Survey preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    1988-04-01

    This report presents the preliminary findings from the first phase of the Environmental Survey of the United States Department of Energy (DOE) Sandia National Laboratories conducted August 17 through September 4, 1987. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with Sandia National Laboratories-Albuquerque (SNLA). The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at SNLA, and interviews with site personnel. 85 refs., 49 figs., 48 tabs.

  19. Ruiz Volcano: Preliminary report

    Science.gov (United States)

    Ruiz Volcano, Colombia (4.88°N, 75.32°W). All times are local (= GMT -5 hours).An explosive eruption on November 13, 1985, melted ice and snow in the summit area, generating lahars that flowed tens of kilometers down flank river valleys, killing more than 20,000 people. This is history's fourth largest single-eruption death toll, behind only Tambora in 1815 (92,000), Krakatau in 1883 (36,000), and Mount Pelée in May 1902 (28,000). The following briefly summarizes the very preliminary and inevitably conflicting information that had been received by press time.

  20. Analyse van kwalitatief onderzoeksmateriaal

    NARCIS (Netherlands)

    Wester, F.P.J.

    2004-01-01

    Qualitative research is characterised by its analytical goals: the development of categories, the elaboration of concepts or the formulation of a theory. Because of this analytical openness, the research design shows successive phases, each with its own objective and specific demands for data collec

  1. Analyse van kwalitatief onderzoeksmateriaal

    NARCIS (Netherlands)

    Wester, F.P.J.

    2004-01-01

    Qualitative research is characterised by its analytical goals: the development of categories, the elaboration of concepts or the formulation of a theory. Because of this analytical openness, the research design shows successive phases, each with its own objective and specific demands for data collec

  2. Autonomous analyser platforms for remote monitoring of water quality

    OpenAIRE

    Diamond, Dermot; Cleary, John; Maher, Damien; Kim, Jung Ho; Lau, King-Tong

    2011-01-01

    This paper describes progress in the realization of reliable, relatively low-cost autonomous microfluidic analysers that are capable of monitoring the chemistry of water bodies for significant periods of time (weeks, months) without human intervention. The data generated is transmitted wireless to a remote web server and transferred to a web-database that renders data access location independent. Preliminary results obtained from a ‘matchbox’ scale analyzer are also presented and routes to...

  3. Analysing international relations

    DEFF Research Database (Denmark)

    Corry, Olaf

    2014-01-01

    the different purposes of theory, how theory can be used to shape your analytical strategy and some of the pitfalls you need to be aware of. Throughout I refer to theories and concepts from across the module that you will be fairly familiar with by now. But I will also make some new distinctions to give...... a better understanding of what theories are, a clearer sense of what they can be used for, and a greater awareness of their differences, strengths and limitations. The chapter proceeds as follows: In Section 1 I look at what theories are and how they work – either by simplifying reality or complicating...... matters by depicting reality in new ways. I then show how different theories rely on different ‘pictures’ of what makes up the international system. Section 2 shows how theories differ in terms of their scope, their aims and their purposes. Section 3 explores some of the choices to be made when using...

  4. Closed rhinoplasty:effects and changes on voice - a preliminary report

    Institute of Scientific and Technical Information of China (English)

    Giuseppe Guarro; Romano Mafifa; Barbara Rasile; Carmine Alfano

    2016-01-01

    Aim: Effects of rhinoplasty were already studied from many points of view: otherwise poor is scientific production focused on changes of voice after rhinoplasty. This preliminary study analyzed objectively and subjectively these potential effects on 19 patients who underwent exclusively closed rhinoplasty.Methods: This preliminary evaluation was conducted from September 2012 to May 2013 and 19 patients have undergone primary rhinoplasty with exclusively closed approach (7 males, 12 females). All patients were evaluated before and 6 months after surgery. Each of them answered to a questionnaire (Voice Handicap Index Score) and the voice was recorded for spectrographic analysis: this system allowed to perform the measurement of the intensity and frequency of vowels (“A” and “E”) and nasal consonants (“N” and “M”) before and after surgery. Data were analysed with the Mann-Whitney test.Results: Sixteen patients showed statistically significant differences after surgery. It was detected in 69% of cases an increased frequency of emission of the consonant sounds (P = 0.046), while in 74% of cases the same phenomenon was noticed for vowel sounds (P = 0.048).Conclusion: Many patients who undergo rhinoplasty think that the intervention only leads to anatomical changes and improvement of respiratory function. The surgeon should instead accurately inform patients about the potential effects on the voice. This preliminary study reveals the significant effects of closed rhinoplasty on the human voice.

  5. NLTE analyses of sdB stars: progress and prospects

    CERN Document Server

    Przybilla, N; Edelmann, H

    2005-01-01

    We report on preliminary results of a hybrid non-LTE analysis of high-resolution, high-S/N spectra of the helium-rich subdwarf B star Feige49 and the helium-poor sdB HD205805. Non-LTE effects are found to have a notable impact on the stellar parameter and abundance determination. In particular the HeI lines show significant deviations from detailed balance, with the computed equivalent widths strengthened by up to ~35%. Non-LTE abundance corrections for the metals (C, N, O, Mg, S) are of the order ~0.05-0.25 dex on the mean, while corrections of up to ~0.7 dex are derived for individual transitions. The non-LTE approach reduces systematic trends and the statistical uncertainties in the abundance determination. Consequently, non-LTE analyses of a larger sample of objects have the potential to put much tighter constraints on the formation history of the different sdB populations than currently discussed.

  6. Severe accident recriticality analyses (SARA)

    DEFF Research Database (Denmark)

    Frid, W.; Højerup, C.F.; Lindholm, I.

    2001-01-01

    three computer codes and to further develop and adapt them for the task. The codes were SIMULATE-3K, APROS and RECRIT. Recriticality analyses were carried out for a number of selected reflooding transients for the Oskarshamn 3 plant in Sweden with SIMULATE-3K and for the Olkiluoto I plant in Finland...... with all three codes. The core initial and boundary conditions prior to recriticality have been studied with the severe accident codes SCDAP/RELAP5, MELCOR and MAAP4. The results of the analyses show that all three codes predict recriticality-both super-prompt power bursts and quasi steady-state power...... generation-for the range of parameters studied, i.e. with core uncovering and heat-up to maximum core temperatures of approximately 1800 K, and water flow rates of 45-2000 kg s(-1) injected into the downcomer. Since recriticality takes place in a small fraction of the core, the power densities are high...

  7. Analysing Protocol Stacks for Services

    DEFF Research Database (Denmark)

    Gao, Han; Nielson, Flemming; Nielson, Hanne Riis

    2011-01-01

    We show an approach, CaPiTo, to model service-oriented applications using process algebras such that, on the one hand, we can achieve a certain level of abstraction without being overwhelmed by the underlying implementation details and, on the other hand, we respect the concrete industrial...... standards used for implementing the service-oriented applications. By doing so, we will be able to not only reason about applications at different levels of abstractions, but also to build a bridge between the views of researchers on formal methods and developers in industry. We apply our approach...... to the financial case study taken from Chapter 0-3. Finally, we develop a static analysis to analyse the security properties as they emerge at the level of concrete industrial protocols....

  8. Hydrogen Analyses in the EPR

    Energy Technology Data Exchange (ETDEWEB)

    Worapittayaporn, S.; Eyink, J.; Movahed, M. [AREVA NP GmbH, P.O. Box 3220, D-91050 Erlangen (Germany)

    2008-07-01

    In severe accidents with core melting large amounts of hydrogen may be released into the containment. The EPR provides a combustible gas control system to prevent hydrogen combustion modes with the potential to challenge the containment integrity due to excessive pressure and temperature loads. This paper outlines the approach for the verification of the effectiveness and efficiency of this system. Specifically, the justification is a multi-step approach. It involves the deployment of integral codes, lumped parameter containment codes and CFD codes and the use of the sigma criterion, which provides the link to the broad experimental data base for flame acceleration (FA) and deflagration to detonation transition (DDT). The procedure is illustrated with an example. The performed analyses show that hydrogen combustion at any time does not lead to pressure or temperature loads that threaten the containment integrity of the EPR. (authors)

  9. Uncertainty and Sensitivity Analyses Plan

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, J.C.; Ramsdell, J.V. Jr.

    1993-04-01

    Hanford Environmental Dose Reconstruction (HEDR) Project staff are developing mathematical models to be used to estimate the radiation dose that individuals may have received as a result of emissions since 1944 from the US Department of Energy's (DOE) Hanford Site near Richland, Washington. An uncertainty and sensitivity analyses plan is essential to understand and interpret the predictions from these mathematical models. This is especially true in the case of the HEDR models where the values of many parameters are unknown. This plan gives a thorough documentation of the uncertainty and hierarchical sensitivity analysis methods recommended for use on all HEDR mathematical models. The documentation includes both technical definitions and examples. In addition, an extensive demonstration of the uncertainty and sensitivity analysis process is provided using actual results from the Hanford Environmental Dose Reconstruction Integrated Codes (HEDRIC). This demonstration shows how the approaches used in the recommended plan can be adapted for all dose predictions in the HEDR Project.

  10. Pawnee Nation Energy Option Analyses

    Energy Technology Data Exchange (ETDEWEB)

    Matlock, M.; Kersey, K.; Riding In, C.

    2009-07-21

    Pawnee Nation of Oklahoma Energy Option Analyses In 2003, the Pawnee Nation leadership identified the need for the tribe to comprehensively address its energy issues. During a strategic energy planning workshop a general framework was laid out and the Pawnee Nation Energy Task Force was created to work toward further development of the tribe’s energy vision. The overarching goals of the “first steps” project were to identify the most appropriate focus for its strategic energy initiatives going forward, and to provide information necessary to take the next steps in pursuit of the “best fit” energy options. Description of Activities Performed The research team reviewed existing data pertaining to the availability of biomass (focusing on woody biomass, agricultural biomass/bio-energy crops, and methane capture), solar, wind and hydropower resources on the Pawnee-owned lands. Using these data, combined with assumptions about costs and revenue streams, the research team performed preliminary feasibility assessments for each resource category. The research team also reviewed available funding resources and made recommendations to Pawnee Nation highlighting those resources with the greatest potential for financially-viable development, both in the near-term and over a longer time horizon. Findings and Recommendations Due to a lack of financial incentives for renewable energy, particularly at the state level, combined mediocre renewable energy resources, renewable energy development opportunities are limited for Pawnee Nation. However, near-term potential exists for development of solar hot water at the gym, and an exterior wood-fired boiler system at the tribe’s main administrative building. Pawnee Nation should also explore options for developing LFGTE resources in collaboration with the City of Pawnee. Significant potential may also exist for development of bio-energy resources within the next decade. Pawnee Nation representatives should closely monitor

  11. Preliminary Analysis of Google+'s Privacy

    OpenAIRE

    2011-01-01

    In this paper we provide a preliminary analysis of Google+ privacy. We identified that Google+ shares photo metadata with users who can access the photograph and discuss its potential impact on privacy. We also identified that Google+ encourages the provision of other names including maiden name, which may help criminals performing identity theft. We show that Facebook lists are a superset of Google+ circles, both functionally and logically, even though Google+ provides a better user interfac...

  12. A Preliminary Jupiter Model

    CERN Document Server

    Hubbard, W B

    2016-01-01

    In anticipation of new observational results for Jupiter's axial moment of inertia and gravitational zonal harmonic coefficients from the forthcoming Juno orbiter, we present a number of preliminary Jupiter interior models. We combine results from ab initio computer simulations of hydrogen-helium mixtures, including immiscibility calculations, with a new nonperturbative calculation of Jupiter's zonal harmonic coefficients, to derive a self-consistent model for the planet's external gravity and moment of inertia. We assume helium rain modified the interior temperature and composition profiles. Our calculation predicts zonal harmonic values to which measurements can be compared. Although some models fit the observed (pre-Juno) second- and fourth-order zonal harmonics to within their error bars, our preferred reference model predicts a fourth-order zonal harmonic whose absolute value lies above the pre-Juno error bars. This model has a dense core of about 12 Earth masses, and a hydrogen-helium-rich envelope with...

  13. A Preliminary Jupiter Model

    Science.gov (United States)

    Hubbard, W. B.; Militzer, B.

    2016-03-01

    In anticipation of new observational results for Jupiter's axial moment of inertia and gravitational zonal harmonic coefficients from the forthcoming Juno orbiter, we present a number of preliminary Jupiter interior models. We combine results from ab initio computer simulations of hydrogen-helium mixtures, including immiscibility calculations, with a new nonperturbative calculation of Jupiter's zonal harmonic coefficients, to derive a self-consistent model for the planet's external gravity and moment of inertia. We assume helium rain modified the interior temperature and composition profiles. Our calculation predicts zonal harmonic values to which measurements can be compared. Although some models fit the observed (pre-Juno) second- and fourth-order zonal harmonics to within their error bars, our preferred reference model predicts a fourth-order zonal harmonic whose absolute value lies above the pre-Juno error bars. This model has a dense core of about 12 Earth masses and a hydrogen-helium-rich envelope with approximately three times solar metallicity.

  14. CHEMICAL ANALYSES OF SODIUM SYSTEMS FINAL REPORT

    Energy Technology Data Exchange (ETDEWEB)

    Greenhalgh, W. O.; Yunker, W. H.; Scott, F. A.

    1970-06-01

    BNWL-1407 summarizes information gained from the Chemical Analyses of Sodium Systems Program pursued by Battelle- Northwest over the period from July 1967 through June 1969. Tasks included feasibility studies for performing coulometric titration and polarographic determinations of oxygen in sodium, and the development of new separation techniques for sodium impurities and their subsequent analyses. The program was terminated ahead of schedule so firm conclusions were not obtained in all areas of the work. At least 40 coulometric titrations were carried out and special test cells were developed for coulometric application. Data indicated that polarographic measurements are theoretically feasible, but practical application of the method was not verified. An emission spectrographic procedure for trace metal impurities was developed and published. Trace metal analysis by a neutron activation technique was shown to be feasible; key to the success of the activation technique was the application of a new ion exchange resin which provided a sodium separation factor of 10{sup 11}. Preliminary studies on direct scavenging of trace metals produced no conclusive results.

  15. Thermal energy storage in aquifiers: preliminary information

    Energy Technology Data Exchange (ETDEWEB)

    Allen, R.D.

    1979-12-01

    Topics discussed include: conceptual designs; numerical modelling; field experiments; relevant technical information; feasibility studies; preliminary aquifer selection considerations; and preliminary design and operating considerations. (TFD)

  16. Molecular ecological network analyses

    Directory of Open Access Journals (Sweden)

    Deng Ye

    2012-05-01

    Full Text Available Abstract Background Understanding the interaction among different species within a community and their responses to environmental changes is a central goal in ecology. However, defining the network structure in a microbial community is very challenging due to their extremely high diversity and as-yet uncultivated status. Although recent advance of metagenomic technologies, such as high throughout sequencing and functional gene arrays, provide revolutionary tools for analyzing microbial community structure, it is still difficult to examine network interactions in a microbial community based on high-throughput metagenomics data. Results Here, we describe a novel mathematical and bioinformatics framework to construct ecological association networks named molecular ecological networks (MENs through Random Matrix Theory (RMT-based methods. Compared to other network construction methods, this approach is remarkable in that the network is automatically defined and robust to noise, thus providing excellent solutions to several common issues associated with high-throughput metagenomics data. We applied it to determine the network structure of microbial communities subjected to long-term experimental warming based on pyrosequencing data of 16 S rRNA genes. We showed that the constructed MENs under both warming and unwarming conditions exhibited topological features of scale free, small world and modularity, which were consistent with previously described molecular ecological networks. Eigengene analysis indicated that the eigengenes represented the module profiles relatively well. In consistency with many other studies, several major environmental traits including temperature and soil pH were found to be important in determining network interactions in the microbial communities examined. To facilitate its application by the scientific community, all these methods and statistical tools have been integrated into a comprehensive Molecular Ecological

  17. A preliminary examination of genetic diversity in the Indian false vampire bat Megaderma lyra

    Directory of Open Access Journals (Sweden)

    Emmanuvel Rajan, K.

    2006-12-01

    Full Text Available Habitat loss and fragmentation have serious consequences for species extinction as well as genetic diversity within a species. Random Amplified Polymorphic DNA (RAPD analysis was employed to assess the genetic diversity within and between four natural populations of M. lyra. Our results suggest that the genetic diversity varied from 0.21 to 0.26 with a mean of 0.11 to 0.13 (± SD. The mean Gst value of 0.15 was obtained from all four populations and estimated average Nm (1.41 showing gene flow between the populations. AMOVA analysis showed 88.96% within and 11.04% among the studied populations. Cluster analyses of RAPD phenotypes showed that specimens were not grouped by geographical origin. The genetic diversity found in the M. lyra population may be explained by its breeding behaviors. Though preliminary, the results indicate that all four populations should be considered to maintain the genetic diversity.

  18. Home Textile Exports Show Recovery Signs

    Institute of Scientific and Technical Information of China (English)

    Yao Lan; Guoyun

    2010-01-01

    @@ In this article we have analysed the export performance of Chinese main home textile products, including bedding products, carpet, curtain and towel based on official export data during the first eight months of 2010.

  19. Perturbation analyses of intermolecular interactions

    Science.gov (United States)

    Koyama, Yohei M.; Kobayashi, Tetsuya J.; Ueda, Hiroki R.

    2011-08-01

    Conformational fluctuations of a protein molecule are important to its function, and it is known that environmental molecules, such as water molecules, ions, and ligand molecules, significantly affect the function by changing the conformational fluctuations. However, it is difficult to systematically understand the role of environmental molecules because intermolecular interactions related to the conformational fluctuations are complicated. To identify important intermolecular interactions with regard to the conformational fluctuations, we develop herein (i) distance-independent and (ii) distance-dependent perturbation analyses of the intermolecular interactions. We show that these perturbation analyses can be realized by performing (i) a principal component analysis using conditional expectations of truncated and shifted intermolecular potential energy terms and (ii) a functional principal component analysis using products of intermolecular forces and conditional cumulative densities. We refer to these analyses as intermolecular perturbation analysis (IPA) and distance-dependent intermolecular perturbation analysis (DIPA), respectively. For comparison of the IPA and the DIPA, we apply them to the alanine dipeptide isomerization in explicit water. Although the first IPA principal components discriminate two states (the α state and PPII (polyproline II) + β states) for larger cutoff length, the separation between the PPII state and the β state is unclear in the second IPA principal components. On the other hand, in the large cutoff value, DIPA eigenvalues converge faster than that for IPA and the top two DIPA principal components clearly identify the three states. By using the DIPA biplot, the contributions of the dipeptide-water interactions to each state are analyzed systematically. Since the DIPA improves the state identification and the convergence rate with retaining distance information, we conclude that the DIPA is a more practical method compared with the

  20. Preliminary results in surgery of Parkinson's disease.

    Science.gov (United States)

    Nasser, J A; Confort, C I; Ferraz, A; Bouza, A A

    1998-09-01

    The authors present the preliminary results of 20 patients selected to be operated on between January 1996 and April 1997. These patients presented one of the present indications for stereotactic posteroventral pallidotomy (PVP), such as: rigidity, akinesia/bradykinesia, gait dysfunction, drug induced dyskinesias and tremor. Every patient of this protocol was evaluated by: UPDRS score, Schwab and England scale, Hoehn and Yahr Staging Scale before and after surgery. The results in 3 months showed a remarkable improvement after PVP (P < 0.01) in all functional assessments, except for facial expression, speech and posture. The morbidity was 5%. 5 patients (25%) who were in Hoehn and Yahr 5 underwent a bilateral simultaneous PVP. In 5 patients (25%), who had tremor, during the PVP, VIM thalamotomy was added. These preliminary results, suggest that PVP is highly effective for PD symptoms.

  1. The Preliminaries of a Reference

    DEFF Research Database (Denmark)

    Butler, Graham; Sadl, Urska

    2017-01-01

    by the reasons why the Court after an oral hearing held in the presence of the parties and eight intervening Member States, and after hearing the Advocate General did not deliver one. The comment examines the legal framework, as well as the detailed procedural rules and guidelines that govern the cooperation...... of national courts in the preliminary reference procedure. It highlights the fact that preliminary references can only work when the preliminaries of a reference – the culture of sincere cooperation and litigation, efficient communication and flexible procedural rules – are in place....

  2. Analyses of outcrop and sediment grains observed and collected from the Sirena Deep and Middle Pond of the Mariana Trench

    Science.gov (United States)

    Hand, K. P.; Bartlett, D. H.; Fryer, P.

    2012-12-01

    During a March 2012 expedition we recovered sediments from two locales within the Marina Trench - Middle Pond and Sirena Deep. Samples were recovered from a Niskin bottle deployed on a passive lander platform that released an arm after touching down on the seafloor. The impact of the arm holding the Niskin bottle caused sediments to enter the bottle; this process was seen in images and on video captured by the lander. The combination of imagery and preliminary analyses of the sediments indicates that the Sirena Deep locale is a region of serpentinization and active microbial communities. Images show several outcrops consistent with serpentinization, some of which are coated with filamentous microbial mats. Results and analyses of these samples will be presented.

  3. Preliminary studies to determine the shelf life of HEPA filters

    Energy Technology Data Exchange (ETDEWEB)

    Gilbert, H.; Fretthold, J.K.; Rainer, F. [Lawrence Livermore National Laboratory, CA (United States)] [and others

    1995-02-01

    We have completed a preliminary study using filter media tests and filter qualification tests to investigate the effect of shelf-life on HEPA filter performance. Our media studies showed that the tensile strength decreased with age, but the data were not sufficient to establish a shelf-life. Thermogravimetric analyses demonstrated that one manufacturer had media with low tensile strength due to insufficient binder. The filter qualification tests (heated air and overpressure) conducted on different aged filters showed that filter age is not the primary factor affecting filter performance; materials and the construction design have a greater effect. An unexpected finding of our study was that sub-standard HEPA filters have been installed in DOE facilities despite existing regulations and filter qualification tests. We found that the filter with low tensile strength failed the overpressure test. The same filter had passed the heated air test, but left the filter so structurally weak, it was prone to blow-out. We recommend that DOE initiate a filter qualification program to prevent this occurrence.

  4. Recent sea level change analysed with kernel EOF

    DEFF Research Database (Denmark)

    Nielsen, Allan Aasbjerg; Andersen, Ole Baltazar; Knudsen, Per

    2009-01-01

    -2008. Preliminary analysis shows some interesting features related to climate change and particularly the pulsing of the El Niño/Southern Oscillation. Large scale ocean events associated with the El Niño/Southern Oscillation related signals are conveniently concentrated in the first SSH kernel EOF modes....

  5. A PRELIMINARY JUPITER MODEL

    Energy Technology Data Exchange (ETDEWEB)

    Hubbard, W. B. [Lunar and Planetary Laboratory, The University of Arizona, Tucson, AZ 85721 (United States); Militzer, B. [Department of Earth and Planetary Science, Department of Astronomy, University of California, Berkeley, CA 94720 (United States)

    2016-03-20

    In anticipation of new observational results for Jupiter's axial moment of inertia and gravitational zonal harmonic coefficients from the forthcoming Juno orbiter, we present a number of preliminary Jupiter interior models. We combine results from ab initio computer simulations of hydrogen–helium mixtures, including immiscibility calculations, with a new nonperturbative calculation of Jupiter's zonal harmonic coefficients, to derive a self-consistent model for the planet's external gravity and moment of inertia. We assume helium rain modified the interior temperature and composition profiles. Our calculation predicts zonal harmonic values to which measurements can be compared. Although some models fit the observed (pre-Juno) second- and fourth-order zonal harmonics to within their error bars, our preferred reference model predicts a fourth-order zonal harmonic whose absolute value lies above the pre-Juno error bars. This model has a dense core of about 12 Earth masses and a hydrogen–helium-rich envelope with approximately three times solar metallicity.

  6. Arapahoe NWR diversion reconstruction : Preliminary

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This is a preliminary plan for a diversion reconstruction for Hubbard #2. Oklahoma #1, Dryer, Hill and Crowder sites on the Arapahoe National Wildlife Refuge.

  7. QUALITY ASSESSMENT OF ETHICS ANALYSES FOR HEALTH TECHNOLOGY ASSSESSMENT.

    Science.gov (United States)

    Scott, Anna Mae; Bond, Kenneth; Gutiérrez-Ibarluzea, Iñaki; Hofmann, Björn; Sandman, Lars

    2016-01-01

    Although consideration of ethical issues is recognized as a crucial part of health technology assessment, ethics analysis for HTA is generally perceived as methodologically underdeveloped in comparison to other HTA domains. The aim of our study is (i) to verify existing tools for quality assessment of ethics analyses for HTA, (ii) to consider some arguments for and against the need for quality assessment tools for ethics analyses for HTA, and (iii) to propose a preliminary set of criteria that could be used for assessing the quality of ethics analyses for HTA. We systematically reviewed the literature, reviewed HTA organizations' Web sites, and solicited views from thirty-two experts in the field of ethics for HTA. The database and HTA agency Web site searches yielded 420 references (413 from databases, seven from HTA Web sites). No formal instruments for assessing the quality of ethics analyses for HTA purposes were identified. Thirty-two experts in the field of ethics for HTA from ten countries, who were brought together at two workshops held in Edmonton (Canada) and Cologne (Germany) confirmed the findings from the literature. Generating a quality assessment tool for ethics analyses in HTA would confer considerable benefits, including methodological alignment with other areas of HTA, increase in transparency and transferability of ethics analyses, and provision of common language between the various participants in the HTA process. We propose key characteristics of quality assessment tools for this purpose, which can be applied to ethics analyses for HTA purposes.

  8. Multiple Imputation for Network Analyses

    NARCIS (Netherlands)

    Krause, Robert; Huisman, Mark; Steglich, Christian; Snijders, Thomas

    2016-01-01

    Missing data on network ties is a fundamental problem for network analyses. The biases induced by missing edge data, even when missing completely at random (MCAR), are widely acknowledged and problematic for network analyses (Kossinets, 2006; Huisman & Steglich, 2008; Huisman, 2009). Although model-

  9. Data from the Television Game Show "Friend or Foe?"

    Science.gov (United States)

    Kalist, David E.

    2004-01-01

    The data discussed in this paper are from the television game show "Friend or Foe", and can be used to examine whether age, gender, race, and the amount of prize money affect contestants' strategies. The data are suitable for a variety of statistical analyses, such as descriptive statistics, testing for differences in means or proportions, and…

  10. Home Textile Exports Show Recovery Signs

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    In this article we have analysed the export performance of Chinese main home textile products, including bedding products, carpet, curtain and towel based on official export data during the first eight months of 2010.Let’s first look at the background. The growth in China’s manufacturing

  11. Analysing the Cenozoic depositional record

    DEFF Research Database (Denmark)

    Goledowski, Bartosz; Clausen, O.R.; Nielsen, S.B.

    It is well known that sediment deposition in the North Sea and on the Norwegian Shelf varied significantly during the Cenozoic as a consequence of varying erosion rate mainly in Western Scandinavia, in Scotland and in the Alps. Recent results have demonstrated that a causal relationship exists...... of variations in erosion rates. Here we present the rationale behind the project, the data available and some preliminary results. The dense seismic and well coverage in the area makes it possible to estimate the rate of deposition of matrix mass. Assuming that sediment storage is not important, this provides...

  12. Preliminary results of ground-motion characteristics

    Directory of Open Access Journals (Sweden)

    Francesca Bozzoni

    2012-10-01

    Full Text Available The preliminary results are presented herein for the engineering applications of the characteristics of the ground motion induced by the May 20, 2012, Emilia earthquake. Shake maps are computed to provide estimates of the spatial distribution of the induced ground motion. The signals recorded at the Mirandola (MRN station, the closest to the epicenter, have been processed to obtain acceleration, velocity and displacement response spectra. Ground-motion parameters from the MRN recordings are compared with the corresponding estimates from recent ground-motion prediction equations, and with the spectra prescribed by the current Italian Building Code for different return periods. The records from the MRN station are used to plot the particle orbit (hodogram described by the waveform. The availability of results from geotechnical field tests that were performed at a few sites in the Municipality of Mirandola prior to this earthquake of May 2012 has allowed preliminary assessment of the ground response. The amplification effects at Mirandola are estimated using fully stochastic site-response analyses. The seismic input comprises seven actual records that are compatible with the Italian code-based spectrum that refers to a 475-year return period. The computed acceleration response spectrum and the associated dispersion are compared to the spectra calculated from the recordings of the MRN station. Good agreement is obtained for periods up to 1 s, especially for the peak ground acceleration. For the other periods, the spectral acceleration of the MRN recordings exceeds that of the computed spectra.

  13. 青藏高原东部三种再分析资料与地面气温观测资料的对比分析%Preliminary Comparison and Analyses of Air Temperature at 2m Height between Three Reanalysis Data-Sets and Observation in the East of Qinghai-Xiang Plateau

    Institute of Scientific and Technical Information of China (English)

    李瑞青; 吕世华; 韩博; 高艳红

    2012-01-01

    为了检验再分析资料在青藏高原(下称高原)的适用性,以地面观测资料为标准,综合比较了1989-2009年间NCEP/DOE(简称NCEP)、ERA-interim(ERA)和JRA-25(JRA)三种再分析资料在高原东部地区的月平均地面气温的分布和变化规律。从平均季节变化来看,夏季再分析资料与观测资料的一致性总体好于冬季,其中NCEP资料整体偏低于观测资料,JRA则相反。从线性趋势来看,ERA和JRA资料与观测资料较一致,均表现出高原东部区域整体增暖趋势,而NCEP资料则表现出略微的下降趋势。从年际尺度变化来看,ERA和JRA资料所反映的年际变化和变率特征要好于NCEP资料,并且JRA资料的结果要优于ERA资料。最后,比较了三种再分析资料的质量指数,发现ERA资料质量最好,NCEP资料最差,而且NCEP和JRA资料在近20年质量有变差趋势,ERA资料有变好趋势;ENSO、东亚季风和高原季风对再分析资料地面气温场的质量均有一定的影响。%The monthly mean surface air temperature at 2mfrom the NCEP/DOE,ERA-interim and JRA-25reanalysis data-sets were respectively compared with those observed value at meteorological stations in the east of Qinghai-Xizang Plateau area from 1989to 2009.The results show that the reanalysis air temperature is higher credibility in summer than in winter,the NCEP/DOE reanalysis data is systematically smaller than the observation,while JRA-25is systematically higher.The datasets of ERA-interim,JRA-25and the observation value all show similar warming trends in the east of Qinghai-Xizang Plateau from 1989to 2009,while NCEP/DOE shows a cooling trend instead.When considering the interannual change,the JRA-25reanalysis data shows the best consistency with the observation records,while NCEP/DOE shows the worst.After the analyzing the quality index of three datasets,it is clear that the quality of ERA-interim is better than that of the other two datasets and is improving

  14. A preliminary characterisation of recovered uranium produced by MDR

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Hyuk Il [Korea Atomic Energy Research Inst., Daeduk (Korea, Republic of); Davison, J.; Marsh, G. [British Nuclear Forum, London (United Kingdom)

    1997-10-01

    The CANFLEX-RU fuel to be developed for the future should be verified if it has any major problems in RU handling techniques and related technology development. For this purpose, a preliminary R and D efforts on the RU handling characteristics were executed by joint effort with BNFL in following area. 1) preparation of RU powder by the MDR process 2) Compaction and sintering characteristics of RU powder 3) required special process for the production of CANFLEX-RU fuel 4) characterization of fission product residue composition in the RU powder 5) radiological characterization of RU powder and sintered pellets. Physical characterization of RU UO{sub 2} powder and pellet produced by the MDR process were similar with those of NU UO{sub 2} powder and pellet. The density of RU pellets, however, were higher than those of NU pellets and RU pellets showed little higher values in pore size distributions. RU contained only negligibly low concentrations of fission products and actinides. Especially, the Cs-137 content in the powder (before sintering) were undetectable and therefore would not contaminate the sintering furnace. RU pellet showed higher impurity levels, especially in the Ni content. Radioactivity on the RU powder showed about twice higher value at the surface than those of NU, but showed drastic reduction by distance and became similar at the 1 meter distance. RU pellets showed close coincidence between NU and RU at any distance. This result could be used close coincidence between NU and RU at any distance. This result could be used as a basis of the feasibility assessment on the development of CANFLEX-RU. Through basic research works on the improvement of CANFLEX-RU fabrication processes, compatibility with CANFLEX-NU fabrication process will be evaluated and analysed. (author). 4 refs.

  15. Written Case Analyses and Critical Reflection.

    Science.gov (United States)

    Harrington, Helen L.; And Others

    1996-01-01

    The study investigated the use of case-based pedagogy to develop critical reflection in prospective teachers. Analysis of students written analyses of dilemma-based cases found patterns showing evidence of students open-mindedness, sense of professional responsibility, and wholeheartedness in approach to teaching. (DB)

  16. Hybrid Logical Analyses of the Ambient Calculus

    DEFF Research Database (Denmark)

    Bolander, Thomas; Hansen, Rene Rydhof

    2010-01-01

    In this paper, hybrid logic is used to formulate three control flow analyses for Mobile Ambients, a process calculus designed for modelling mobility. We show that hybrid logic is very well-suited to express the semantic structure of the ambient calculus and how features of hybrid logic can...

  17. Preliminary structural assessment of DEMO vacuum vessel against a vertical displacement event

    Energy Technology Data Exchange (ETDEWEB)

    Mozzillo, Rocco, E-mail: rocco.mozzillo@unina.it [CREATE, University of Naples Federico II, DII, P.le Tecchio 80, 80125, Naples (Italy); Tarallo, Andrea; Marzullo, Domenico [CREATE, University of Naples Federico II, DII, P.le Tecchio 80, 80125, Naples (Italy); Bachmann, Christian [EUROfusion PMU, Boltzmannstraße 2, 85748 Garching (Germany); Di Gironimo, Giuseppe [CREATE, University of Naples Federico II, DII, P.le Tecchio 80, 80125, Naples (Italy); Mazzone, Giuseppe [Unità Tecnica Fusione - ENEA C.R. Frascati, Via E. Fermi 45, 00044 Frascati (Italy)

    2016-11-15

    Highlights: • The paper focuses on a preliminary structural analysis of the current concept design of DEMO vacuum vessel. • The Vacuum Vessel was checked against the VDE in combinations with the weight force of all components that the vessel shall bear. • Different configurations for the vacuum vessel supports are considered, showing that the best solution is VV supported at the lower port. • The analyses evaluated the “P damage” according to RCC-MRx code. - Abstract: This paper focuses on a preliminary structural analysis of the current concept design of DEMO vacuum vessel (VV). The VV structure is checked against a vertical load due to a Vertical Displacement Event in combination with the weight force of all components that the main vessel shall bear. Different configurations for the supports are considered. Results show that the greatest safety margins are reached when the tokamak is supported through the lower ports rather than the equatorial ports, though all analyzed configurations are compliant with RCC-MRx design rules.

  18. A Preliminary Analysis of Reactor Performance Test (LOEP) for a Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyeonil; Park, Su-Ki [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    The final phase of commissioning is reactor performance test, which is to prove the integrated performance and safety of the research reactor at full power with fuel loaded such as neutron power calibration, Control Absorber Rod/Second Shutdown Rod drop time, InC function test, Criticality, Rod worth, Core heat removal with natural mechanism, and so forth. The last test will be safety-related one to assure the result of the safety analysis of the research reactor is marginal enough to be sure about the nuclear safety by showing the reactor satisfies the acceptance criteria of the safety functions such as for reactivity control, maintenance of auxiliaries, reactor pool water inventory control, core heat removal, and confinement isolation. After all, the fuel integrity will be ensured by verifying there is no meaningful change in the radiation levels. To confirm the performance of safety equipment, loss of normal electric power (LOEP), possibly categorized as Anticipated Operational Occurrence (AOO), is selected as a key experiment to figure out how safe the research reactor is before turning over the research reactor to the owner. This paper presents a preliminary analysis of the reactor performance test (LOEP) for a research reactor. The results showed how different the transient between conservative estimate and best estimate will look. Preliminary analyses have shown all probable thermal-hydraulic transient behavior of importance as to opening of flap valve, minimum critical heat flux ratio, the change of flow direction, and important values of thermal-hydraulic parameters.

  19. Preliminary research on the efficacy of virtual reality exposure therapy to treat driving phobia.

    Science.gov (United States)

    Wald, Jaye; Taylor, Steven

    2003-10-01

    This article presents a review of preliminary research of two studies of the efficacy of virtual reality exposure therapy (VRET) to treat driving phobia. Study 1 describes a case study of a patient who completed a 7-day baseline followed by three sessions of VRET. Her peak anxiety decreased within and across sessions. At the post-treatment assessment, her phobic-related symptoms had diminished and she no longer met diagnostic criteria for driving phobia. Clinical improvement was maintained at 1-, 3-, and 7-month follow-up. In study 2, a multiple baseline across-subjects design was used to treat five patients over eight weekly VRET sessions. Visual and statistical analyses showed clear improvement in driving anxiety and avoidance in three patients between pre- and post-treatment assessments, and they no longer met criteria for driving phobia. There was marginal improvement in one patient, and the remaining individual showed no treatment gains. There was negligible change in actual driving frequency for any of the patients. Some gains were lost at the follow-up, particularly for the two individuals with poorer treatment responses. The results from these preliminary studies suggest that VRET may be a promising intervention for treating driving phobia. Avenues for improving treatment outcome are discussed.

  20. Preliminary stabilisation of stormwater biofilters and loss of filter material.

    Science.gov (United States)

    Subramaniam, D N; Mather, P B

    Stabilisation affects performance of stormwater biofilters operating under intermittent wetting and drying, mainly due to wash-off of filter material. Understanding the dynamics of solids wash-off is crucial in designing stormwater biofilters. The current study analysed the dynamics of solids wash-off in stormwater biofilters and quantified the loss of solids from the filter. Four Perspex™ bioretention columns (94 mm internal diameter) were fabricated with a filter layer that contained 8% organic material and were fed with tap water with different numbers of antecedent dry days (0-40 day) at 100 mL/min. Samples were collected from the outflow and tested for particle size distribution and total solids and turbidity. Solids of particle size less than 50 microns were washed off from the filter during the stabilisation period, indicating that no sand particles were washed off. The very first event after commissioning the filter resulted in the highest wash-off of solids (approximately 75 g of fines) while a significant drop in wash-off followed from the second event. An empirical model fitted to the data showed that preliminary stabilisation of a filter occurs in the first three events, during which almost 25% of fines are lost from the filter.

  1. Caligula-Christ: Preliminary Study of a Parallel

    Directory of Open Access Journals (Sweden)

    Lorene M. Birden

    2010-01-01

    Full Text Available Caligula, at the very beginning of the Albert Camus play, conceives a very ambitious project; to surpass the gods and take their place in his empire, in order to decree impossibility. Camus has, however, gone a step further in developing the god-image of his main character through the incorporation of much Christian imagery into the scenes. This aspect of the play seems not to have been noticed by Camus scholars; there is no in-depth study of the use of this imagery. However, Camus scholar Patricia Johnson and the members of the Société des études camusiennes have noted the usefulness of the analysis presented here and the absence of it in previous research. This study, designated as “preliminary,” attempts to prompt further analyses of the question and offers different approaches. It proceeds by intertextual study of Caligula and the gospels (here referred to in Revised Standard Version and brings out aspects of the emperor’s intentions that expose a combination of perversion and similarity in relation to deity. It briefly outlines the sources of this parallel and the reasons for creating it, then details the parallels that show first the reversal of the image of Jesus, then the striking consonance. It ends with interpretations of the parallels and concludes with commentaries on the use of irony to create them.

  2. Preliminary biogeochemical assessment of EPICA LGM and Holocene ice samples

    Science.gov (United States)

    Bulat, S.; Alekhina, I.; Marie, D.; Wagenbach, D.; Raynaud, D.; Petit, J. R.

    2009-04-01

    We are investigating the biological content (biomass and microbial diversity of Aeolian origin) of EPICA ice core within the frame of EPICA Microbiology consortium*. Two ice core sections were selected from EPICA Dome C and Droning Maud Land, both from LGM and Holocene. Preliminary measurements of DOC (dissolved organic content) and microbial cell concentrations have been performed. Both analyses showed the very low biomass and ultra low DOC content. Trace DNA analyses are in a progress. The ice sections were decontaminated in LGGE cold and clean room facilities benefiting the protocol developed for Vostok ice core studies. The melt water was then shared between two party laboratories for a complementary approach in studying microbial content. Prior to biology the melt water was tested for chemical contaminant ions and organic acids, DOC and dust contents. The biological methods included all the spectra of appropriate molecular techniques (gDNA extraction, PCR, clone libraries and sequencing). As preliminary results, both LGM (well identified by dust fallout) and Holocene ice samples (EDC99 and EDML) proved to be extremely clear (i.e. pristine) in terms of biomass (less then 4 cells per ml) and DOC contents (less then 5 ppbC). There was no obvious difference between LGM and Holocene in cell counts, while LGM showed a bit high organic carbon content. The latter in terms of biology means ultra-oligotrophic conditions (i.e., no possibility for heterotrophic life style). In fact no metabolizing microbial cells or propagating populations are expected at these depths at temperature -38oC and lower (limiting life temperature threshold is -20°C). Nevertheless some life seeds brought in Antarctica with precipitation could be well preserved because the age is rather young (21 kyr and less). Trying to identify these aliens and document their distribution during last climate cycle the meltwater was concentrated about 1000 times down. The genomic DNA was extracted and very

  3. Olfactometric analyses or odors measurement by sensorial analyses; Analyses olfactometriques ou mesure des odeurs par analyse sensorielle

    Energy Technology Data Exchange (ETDEWEB)

    Gouronnec, A.M. [Institut de Radioprotection et de Surete Nucleaire (IRSN), 92 - Clamart (France)

    2004-06-15

    The olfactometric analyses presented here are applied to industrial odors being able to generate harmful effects for people. The aim of the olfactometric analyses is to quantify odors, to qualify them or to join a pleasant or an unpleasant character to them (hedonism notion). The aim of this work is at first to present the different measurements carried out, the different measurement methods used and the current applications for each of the methods. (O.M.)

  4. STD studies show spermicides protect against Chlamydia.

    Science.gov (United States)

    1986-01-01

    Evidence which suggests that spermicides provide protection against sexually transmitted diseases (STDs) is accumulating. Laboratory tests have repeatedly demonstrated that spermicides are capable of killing the bacteria responsible for several types of STDs, as well as the virus responsible for acquired immunodeficiency syndrome. Recently, studies conducted in Bangkok, Thailand and in New York City suggest that these protective effects are not confined to the laboratory but that they also occur among women who use spermicides in the real world. In the New York City study, Family Health International (FHI), using data collected by Planned Parenthood of New York City, compared STD prevalence rates for women using different contraceptive methods. Women who used spermicides, in comparison with women who used oral contraceptives (OCs), were 20% less likely to have contracted a STD, 30% less likely to have gonorrhea, and 60% less likely to have chlamydia. In the Thai study, conducted jointly by the FHI and the Ministry of Health, women at high risk of STDs were allocated either to a group which was instructed to use a vaginal sponge impregnated with nonoxynol-9 during intercourse or to a control group which received no vaginal contraceptives. All the women were either sterilized or using OCs, IUDs, or injectable contraceptives. Preliminary results suggest that the women who used the vaginal sponges were significantly less likely to contract chlamydia than the control group. In regard to the incidence of gonorrhea, no differences between the 2 groups was detected. In the Thai study methodological problems forced the researchers to redesign the study. In accordance with the new design, the women in the 2 groups will be crossed over after 6 weeks. This will allow the researchers to examine the effect of using or not using a vaginal spermicide on specific individuals. The findings of the 2 studies have special relevance given the increasing prevalence of STDs in many

  5. PRELIMINARY PROGRAMMED WHOLE—BODY COUNTER

    Institute of Scientific and Technical Information of China (English)

    张少东; 郑文忠; 等

    1995-01-01

    It is capable of giving the initial intakes of radionuclides and the assessment quantitites used in radiation protection according to its measured results of radionuclides in vivo.It is accomplished by providing the software of controlling,interface and internal dose estimation programs to the original iron cabin shielding whole-body counter.The preliminary application shows that its data processing is rapid and correct,and can meet the requirement of rapid internal radioactive contamination monitoring and diagnosing in case of lots of internal contamination subjects happened in nuclear accident.

  6. Impact of ontology evolution on functional analyses.

    Science.gov (United States)

    Groß, Anika; Hartung, Michael; Prüfer, Kay; Kelso, Janet; Rahm, Erhard

    2012-10-15

    Ontologies are used in the annotation and analysis of biological data. As knowledge accumulates, ontologies and annotation undergo constant modifications to reflect this new knowledge. These modifications may influence the results of statistical applications such as functional enrichment analyses that describe experimental data in terms of ontological groupings. Here, we investigate to what degree modifications of the Gene Ontology (GO) impact these statistical analyses for both experimental and simulated data. The analysis is based on new measures for the stability of result sets and considers different ontology and annotation changes. Our results show that past changes in the GO are non-uniformly distributed over different branches of the ontology. Considering the semantic relatedness of significant categories in analysis results allows a more realistic stability assessment for functional enrichment studies. We observe that the results of term-enrichment analyses tend to be surprisingly stable despite changes in ontology and annotation.

  7. Severe Accident Recriticality Analyses (SARA)

    Energy Technology Data Exchange (ETDEWEB)

    Frid, W. [Swedish Nuclear Power Inspectorate, Stockholm (Sweden); Hoejerup, F. [Risoe National Lab. (Denmark); Lindholm, I.; Miettinen, J.; Puska, E.K. [VTT Energy, Helsinki (Finland); Nilsson, Lars [Studsvik Eco and Safety AB, Nykoeping (Sweden); Sjoevall, H. [Teoliisuuden Voima Oy (Finland)

    1999-11-01

    Recriticality in a BWR has been studied for a total loss of electric power accident scenario. In a BWR, the B{sub 4}C control rods would melt and relocate from the core before the fuel during core uncovery and heat-up. If electric power returns during this time-window unborated water from ECCS systems will start to reflood the partly control rod free core. Recriticality might take place for which the only mitigating mechanisms are the Doppler effect and void formation. In order to assess the impact of recriticality on reactor safety, including accident management measures, the following issues have been investigated in the SARA project: 1. the energy deposition in the fuel during super-prompt power burst, 2. the quasi steady-state reactor power following the initial power burst and 3. containment response to elevated quasi steady-state reactor power. The approach was to use three computer codes and to further develop and adapt them for the task. The codes were SIMULATE-3K, APROS and RECRIT. Recriticality analyses were carried out for a number of selected reflooding transients for the Oskarshamn 3 plant in Sweden with SIMULATE-3K and for the Olkiluoto 1 plant in Finland with all three codes. The core state initial and boundary conditions prior to recriticality have been studied with the severe accident codes SCDAP/RELAP5, MELCOR and MAAP4. The results of the analyses show that all three codes predict recriticality - both superprompt power bursts and quasi steady-state power generation - for the studied range of parameters, i. e. with core uncovery and heat-up to maximum core temperatures around 1800 K and water flow rates of 45 kg/s to 2000 kg/s injected into the downcomer. Since the recriticality takes place in a small fraction of the core the power densities are high which results in large energy deposition in the fuel during power burst in some accident scenarios. The highest value, 418 cal/g, was obtained with SIMULATE-3K for an Oskarshamn 3 case with reflooding

  8. Foodstuff analyses show that seafood and water are major perfluoroalkyl acids (PFAAs) sources to humans in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Heo, Jin-Ju; Lee, Ji-Woo [Department of Civil and Environmental Engineering, Pusan National University, Busan, 609-735 (Korea, Republic of); Kim, Seung-Kyu [Department of Marine Science, College of Natural Sciences, Incheon National University, Incheon, 406-772 (Korea, Republic of); Oh, Jeong-Eun, E-mail: jeoh@pusan.ac.kr [Department of Civil and Environmental Engineering, Pusan National University, Busan, 609-735 (Korea, Republic of)

    2014-08-30

    Graphical abstract: - Highlights: • 16 PFAAs in 397 samples of 66 food types and 34 tap water samples were analyzed. • Dietary exposure to PFAAs was estimated by using the PFAAs measured concentrations. • The major contributors of PFAAs dietary exposure were confirmed. - Abstract: We measured concentrations of PFAAs in 397 foods, of 66 types, in Korea, and determined the daily human dietary PFAAs intake and the contribution of each foodstuff to that intake. The PFAAs concentration in the 66 different food types ranged from below the detection limit to 48.3 ng/g. Perfluorooctane sulfonate (PFOS) and long-chain perfluorocarboxylic acids (PFCAs) were the dominant PFAAs in fish, shellfish, and processed foods, while perfluorooctanoic acid (PFOA) and short-chain PFCAs dominated dairy foodstuffs and beverages. The Korean adult dietary intake ranges, estimated for a range of scenarios, were 0.60–3.03 and 0.17–1.68 ng kg{sup −1} bw d{sup −1} for PFOS and PFOA, respectively, which were lower than the total daily intake limits suggested by European Food Safety Authority (PFOS: 150 ng kg{sup −1} bw d{sup −1}; PFOA: 1500 ng kg{sup −1} bw d{sup −1}). The major contributors to PFAAs dietary exposure varied with subject age and PFAAs. For example, fish was a major contributor of PFOS but dairy foods were major contributors of PFOA. However, tap water was a major contributor to PFOA intake when it was the main source of drinking water (rather than bottled water)

  9. Texture analyses show synergetic effects of biomechanical and biochemical stimulation on mesenchymal stem cell differentiation into early phase osteoblasts.

    Science.gov (United States)

    Park, So Hee; Shin, Ji Won; Kang, Yun Gyeong; Hyun, Jin-Sook; Oh, Min Jae; Shin, Jung-Woog

    2014-02-01

    We investigated the structural complexity and texture of the cytoskeleton and nucleus in human mesenchymal stem cells during early phase differentiation into osteoblasts according to the differentiation-induction method: mechanical and/or chemical stimuli. For this, fractal dimension and a number of parameters utilizing the gray-level co-occurrence matrix (GLCM) were calculated based on single-cell images after confirmation of differentiation by immunofluorescence staining. The F-actin and nuclear fractal dimensions were greater in both stimulus groups compared with the control group. The GLCM values for energy and homogeneity were lower in fibers of the F-actin cytoskeleton, indicating a dispersed F-actin arrangement during differentiation. In the nuclei of both stimulus groups, higher values for energy and homogeneity were calculated, indicating that the chromatin arrangement was chaotic during the early phase of differentiation. It was shown and confirmed that combined stimulation with mechanical and chemical factors accelerated differentiation, even in the early phase. Fractal dimension analysis and GLCM methods have the potential to provide a framework for further investigation of stem cell differentiation.

  10. Genomic Analyses of Musashi1 Downstream Targets Show a Strong Association with Cancer-related Processes*S⃞

    OpenAIRE

    2009-01-01

    Musashi1 (Msi1) is a highly conserved RNA-binding protein with pivotal functions in stem cell maintenance, nervous system development, and tumorigenesis. Despite its importance, only three direct mRNA targets have been characterized so far: m-numb, CDKN1A, and c-mos. Msi1 has been shown to affect their translation by binding to short elements located in the 3′-untranslated region. To better understand Msi1 functions, we initially performed an RIP-Chip analysis in H...

  11. Tract-Specific Analyses of Diffusion Tensor Imaging Show Widespread White Matter Compromise in Autism Spectrum Disorder

    Science.gov (United States)

    Shukla, Dinesh K.; Keehn, Brandon; Muller, Ralph-Axel

    2011-01-01

    Background: Previous diffusion tensor imaging (DTI) studies have shown white matter compromise in children and adults with autism spectrum disorder (ASD), which may relate to reduced connectivity and impaired function of distributed networks. However, tract-specific evidence remains limited in ASD. We applied tract-based spatial statistics (TBSS)…

  12. Mobile biofeedback of heart rate variability in patients with diabetic polyneuropathy: a preliminary study.

    Science.gov (United States)

    Druschky, Katrin; Druschky, Achim

    2015-09-01

    Biofeedback of heart rate variability (HRV) was applied to patients with diabetic polyneuropathy using a new mobile device allowing regularly scheduled self-measurements without the need of visits to a special autonomic laboratory. Prolonged generation of data over an eight-week period facilitated more precise investigation of cardiac autonomic function and assessment of positive and negative trends of HRV parameters over time. Statistical regression analyses revealed significant trends in 11 of 17 patients, while no significant differences were observed when comparing autonomic screening by short-term HRV and respiratory sinus arrhythmia at baseline and after the 8 weeks training period. Four patients showed positive trends of HRV parameters despite the expected progression of cardiac autonomic dysfunction over time. Patient compliance was above 50% in all but two patients. The results of this preliminary study indicate a good practicality of the handheld device and suggest a potential positive effect on cardiac autonomic neuropathy in patients with type 2 diabetes.

  13. Mitogenomic analyses from ancient DNA

    DEFF Research Database (Denmark)

    Paijmans, Johanna L.A.; Gilbert, M Thomas P; Hofreiter, Michael

    2013-01-01

    . To date, at least 124 partially or fully assembled mitogenomes from more than 20 species have been obtained, and, given the rapid progress in sequencing technology, this number is likely to dramatically increase in the future. The increased information content offered by analysing full mitogenomes has...... (mitogenomes). Such studies were initially limited to analyses of extant organisms, but developments in both DNA sequencing technologies and general methodological aspects related to working with degraded DNA have resulted in complete mitogenomes becoming increasingly popular for ancient DNA studies as well...... analyses (whether using modern or ancient DNA) were largely restricted to the analysis of short fragments of the mitochondrial genome. However, due to many technological advances during the past decade, a growing number of studies have explored the power of complete mitochondrial genome sequences...

  14. Fire and collapse, Faculty of Architecture building, Delft University of Technology: Data collection and preliminary analyses

    NARCIS (Netherlands)

    Meacham, B.; Park, H.; Engelhardt, M.; Kirk, A.; Kodur, V.; Straalen, IJ.J.; Maljaars, J.; Weeren, K. van; Feijter, R. de; Both, K.

    2010-01-01

    On the morning of May 13, 2008, a fire that started in a coffee vending machine on the 6th floor of the 13-story Faculty of Architecture Building at the Delft University of Technology (TUD), Delft, the Netherlands, quickly developed into an extreme loading event. Although all building occupants evac

  15. Preliminary report on digitalization of renal microangiograms used in analysing renal parenchymal diseases.

    Science.gov (United States)

    Takahashi, M; Kaneko, M

    1983-01-01

    Glomerulography is a useful method for the angiographic diagnosis of various renal parenchymal diseases. A new system for digitalization of the glomerulogram has been developed using a high resolution television camera and a CT computer. We describe the fundamental procedures involved in the clinical application of digital glomerulography by applying this method to a renal microangiogram of a cow. This new method aids a clearer understanding of the detailed microvasculatures by providing better magnification and storage and allowing for further processing of the original analogue images. With a computer printout of any part of the glomerulogram also possible, an estimation of the glomerular counts and their distribution can now be given for any unit of cross-sectional area of the renal cortex.

  16. Preliminary plasma spectrometric analyses for selected elements in some geothermal waters from Cerro Prieto, Mexico

    Science.gov (United States)

    Ball, J.W.; Jenne, E.A.

    1983-01-01

    As part of a cooperative study with Dr. Alfred Truesdell, water samples collected from geothermal power production wells at Cerro Prieto, Mexico, were analyzed for selected elements by d.c. argon plasma emission spectroscopy. Spectral interferences due to the presence of high concentrations of Ca, Si, Na and K in these water affected the apparent concentration values obtained. These effects were evaluated and correction techniques were developed and applied to the analytical values. Precipitates present in the samples at the time of analysis adversely affected the accuracy, precision and interpretability of the data. (USGS)

  17. Fire and collapse, Faculty of Architecture building, Delft University of Technology: Data collection and preliminary analyses

    NARCIS (Netherlands)

    Meacham, B.; Park, H.; Engelhardt, M.; Kirk, A.; Kodur, V.; Straalen, IJ.J.; Maljaars, J.; Weeren, K. van; Feijter, R. de; Both, K.

    2010-01-01

    On the morning of May 13, 2008, a fire that started in a coffee vending machine on the 6th floor of the 13-story Faculty of Architecture Building at the Delft University of Technology (TUD), Delft, the Netherlands, quickly developed into an extreme loading event. Although all building occupants

  18. Size and depth of vocabulary knowledge: what the research shows

    OpenAIRE

    Schmitt, Norbert

    2014-01-01

    When discussing vocabulary, a distinction is often made between size of vocabulary (number of known words) and depth of knowledge (how well those words are known). However, the relationship between the two constructs is still unclear. Some scholars argue that there is little real difference between the two, while regression analyses show that depth typically adds unique explanatory power compared to size alone. Ultimately, the relationship between size and depth of vocabulary knowledge depend...

  19. Mixtures of thermostable enzymes show high performance in biomass saccharification.

    Science.gov (United States)

    Kallioinen, Anne; Puranen, Terhi; Siika-aho, Matti

    2014-07-01

    Optimal enzyme mixtures of six Trichoderma reesei enzymes and five thermostable enzyme components were developed for the hydrolysis of hydrothermally pretreated wheat straw, alkaline oxidised sugar cane bagasse and steam-exploded bagasse by statistically designed experiments. Preliminary studies to narrow down the optimization parameters showed that a cellobiohydrolase/endoglucanase (CBH/EG) ratio of 4:1 or higher of thermostable enzymes gave the maximal CBH-EG synergy in the hydrolysis of hydrothermally pretreated wheat straw. The composition of optimal enzyme mixtures depended clearly on the substrate and on the enzyme system studied. The optimal enzyme mixture of thermostable enzymes was dominated by Cel7A and required a relatively high amount of xylanase, whereas with T. reesei enzymes, the high proportion of Cel7B appeared to provide the required xylanase activity. The main effect of the pretreatment method was that the required proportion of xylanase was higher and the proportion of Cel7A lower in the optimized mixture for hydrolysis of alkaline oxidised bagasse than steam-exploded bagasse. In prolonged hydrolyses, less Cel7A was generally required in the optimal mixture. Five-component mixtures of thermostable enzymes showed comparable hydrolysis yields to those of commercial enzyme mixtures.

  20. Drilling and production - Economics show CO2 EOR potential

    Science.gov (United States)

    Dubois, M.K.; Byrnes, A.P.

    2000-01-01

    CO2 EOR may be the key to recovering hundreds of millions of bbl of trapped oil from the mature fields in central Kansas. A simple model aided in assessing the economics of CO2 EOR for central Kansas and the Midcontinent. The model used CO2 Prophet, a DOE freeware reservoir numerical simulation program, to determine reservoir performance, including injected and produced fluid rates, and CO2 utilization. Economic parameters, e.g., oil price, CO2 costs, capital costs, net revenue interest, production taxes, and lease operating expenses, are typical for anticipated conditions in the region and present price climate. Preliminary economic analysis shows that CO2 EOR should give an internal rate of return (IRR) > 20%, before income tax, assuming oil sells for $20/bbl, CO2 costs $1/million cu ft, and gross utilization is 10 million cu ft of CO2/bbl of oil recovered. If the CO2 is reduced to $0.75/million cu ft, an oil price of $17/bbl yields an IRR of 20%. Reservoir and economic modeling shows that IRR is most sensitive to oil price and CO2 cost.

  1. Fabrics China Creation Show Hold in Shanghai

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ On August 5-6th.the 3rd Fabrics China Creation Show(one series events of Reach & Touch),organized by China National Textile & Apparel Council and National Textile Development Center,was held in Shanghai,aiming to providing textile producers and designers a platform to show their inspirations and creative ideas in fabric design.

  2. Serving Up Activities for TV Cooking Shows.

    Science.gov (United States)

    Katchen, Johanna E.

    This paper documents a presentation given on the use of English-language television cooking shows in English-as-a-Second-Language (ESL) and English-as-a-Foreign-Language (EFL) classrooms in Taiwan. Such shows can be ideal for classroom use, since they have a predictable structure consisting of short segments, are of interest to most students,…

  3. FY01 Supplemental Science and Performance Analyses, Volume 1: Scientific Bases and Analyses, Rev 00

    Energy Technology Data Exchange (ETDEWEB)

    David Dobson

    2001-06-30

    The U.S. Department of Energy (DOE) is considering the possible recommendation of a site at Yucca Mountain, Nevada, for development as a geologic repository for the disposal of high-level radioactive waste and spent nuclear fuel. To facilitate public review and comment, in May 2001 the DOE released the Yucca Mountain Science and Engineering Report (S&ER) (DOE 2001 [DIRS 153849]), which presents technical information supporting the consideration of the possible site recommendation. The report summarizes the results of more than 20 years of scientific and engineering studies. A decision to recommend the site has not been made: the DOE has provided the S&ER and its supporting documents as an aid to the public in formulating comments on the possible recommendation. When the S&ER (DOE 2001 [DIRS 153849]) was released, the DOE acknowledged that technical and scientific analyses of the site were ongoing. Therefore, the DOE noted in the Federal Register Notice accompanying the report (66 FR 23 013 [DIRS 155009], p. 2) that additional technical information would be released before the dates, locations, and times for public hearings on the possible recommendation were announced. This information includes: (1) the results of additional technical studies of a potential repository at Yucca Mountain, contained in this FY01 Supplemental Science and Performance Analyses: Vol. 1, Scientific Bases and Analyses; and FY01 Supplemental Science and Performance Analyses: Vol. 2, Performance Analyses (McNeish 2001 [DIRS 155023]) (collectively referred to as the SSPA) and (2) a preliminary evaluation of the Yucca Mountain site's preclosure and postclosure performance against the DOE's proposed site suitability guidelines (10 CFR Part 963 [64 FR 67054] [DIRS 124754]). By making the large amount of information developed on Yucca Mountain available in stages, the DOE intends to provide the public and interested parties with time to review the available materials and to formulate and

  4. Descriptive Analyses of Mechanical Systems

    DEFF Research Database (Denmark)

    Andreasen, Mogens Myrup; Hansen, Claus Thorp

    2003-01-01

    Forord Produktanalyse og teknologianalyse kan gennmføres med et bredt socio-teknisk sigte med henblik på at forstå kulturelle, sociologiske, designmæssige, forretningsmæssige og mange andre forhold. Et delområde heri er systemisk analyse og beskrivelse af produkter og systemer. Nærværende kompend...

  5. Evaluation "Risk analyses of agroparks"

    NARCIS (Netherlands)

    Ge, L.

    2011-01-01

    Dit TransForum project richt zich op analyse van de onzekerheden en mogelijkheden van agroparken. Dit heeft geleid tot een risicomodel dat de kwalitatieve en/of kwantitatieve onzekerheden van een agropark project in kaart brengt. Daarmee kunnen maatregelen en managementstrategiën worden geïdentifice

  6. 45 CFR 150.217 - Preliminary determination.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Preliminary determination. 150.217 Section 150.217... Are Failing To Substantially Enforce HIPAA Requirements § 150.217 Preliminary determination. If, at... designees). (b) Notifies the State of CMS's preliminary determination that the State has failed to...

  7. Voyeurismo Televisivo, Reality Shows e Brasilidade Televisiva

    Directory of Open Access Journals (Sweden)

    Suzana Kilpp

    2008-12-01

    Full Text Available In the last years we watched a boom of reality shows in the media and also in the academic production specialized in this subject. It remains, however, a epistemological gap related to the aesthetic and techniques (which are related to the televisions grammars that TV uses in these programs to enunciate ethics directions to its own voyeurism, that goes far beyond reality shows, having repercussions on social imaginary of transparency and surveillance, and the redesign of public and private spaces. In this gap, the article points out the debate of Brazilian reality shows in the perspective of the televisions grammars.

  8. Fecal Transplant Shows Early Promise Against Autism

    Science.gov (United States)

    ... 163263.html Fecal Transplant Shows Early Promise Against Autism Small study found giving healthy gut bacteria to ... study suggests a novel treatment for kids with autism: Give these young patients a fresh supply of ...

  9. Poverty Harder on Women's Hearts, Research Shows

    Science.gov (United States)

    ... page: https://medlineplus.gov/news/fullstory_163168.html Poverty Harder on Women's Hearts, Research Shows Poor females ... reduce the burden of cardiovascular disease around the world," Peters said. The study findings were published online ...

  10. Diabetes Drug Shows Promise Against Parkinson's

    Science.gov (United States)

    ... fullstory_167612.html Diabetes Drug Shows Promise Against Parkinson's Byetta improved symptoms of motor disease in small, ... may do double duty as a treatment for Parkinson's disease, a new study suggests. "This is a ...

  11. UV Photography Shows Hidden Sun Damage

    Science.gov (United States)

    ... mcat1=de12", ]; for (var c = 0; c UV photography shows hidden sun damage A UV photograph gives ... developing skin cancer and prematurely aged skin. Normal photography UV photography 18 months of age: This boy's ...

  12. Study Shows How Zika Attacks Infant Brain

    Science.gov (United States)

    ... gov/news/fullstory_162514.html Study Shows How Zika Attacks Infant Brain Virus can copy itself thousands ... New research paints a chilling portrait of how Zika ravages the infant brain. Scientists from the U.S. ...

  13. Fabrics China Creation Show Held in Shanghai

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    On August 5-6th,the 3rd Fabrics China Creation Show (one series events of Reach & Touch),organized by China National Textile & Apparel Council and National Textile Development Center,was held in Shanghai,

  14. Voyeurismo Televisivo, Reality Shows e Brasilidade Televisiva

    OpenAIRE

    Suzana Kilpp

    2008-01-01

    In the last years we watched a boom of reality shows in the media and also in the academic production specialized in this subject. It remains, however, a epistemological gap related to the aesthetic and techniques (which are related to the televisions grammars) that TV uses in these programs to enunciate ethics directions to its own voyeurism, that goes far beyond reality shows, having repercussions on social imaginary of transparency and surveillance, and the redesign of public and private s...

  15. Development and preliminary validation of the Opioid Abuse Risk Screener.

    Science.gov (United States)

    Henrie-Barrus, Patricia; Averill, Lynnette A; Sudweeks, Richard R; Averill, Christopher L; Mota, Natalie

    2016-01-01

    Prescription opioid drug abuse has reached epidemic proportions. Individuals with chronic pain represent a large population at considerable risk of abusing opioids. The Opioid Abuse Risk Screener was developed as a comprehensive self-administered measure of potential risk that includes a wide range of critical elements noted in the literature to be relevant to opioid risk. The creation, refinement, and preliminary modeling of the item pool, establishment of preliminary concurrent validity, and the determination of the factor structure are presented. The initial development and validation of the Opioid Abuse Risk Screener shows promise for effective risk stratification.

  16. Development and preliminary validation of the Opioid Abuse Risk Screener

    Directory of Open Access Journals (Sweden)

    Patricia Henrie-Barrus

    2016-05-01

    Full Text Available Prescription opioid drug abuse has reached epidemic proportions. Individuals with chronic pain represent a large population at considerable risk of abusing opioids. The Opioid Abuse Risk Screener was developed as a comprehensive self-administered measure of potential risk that includes a wide range of critical elements noted in the literature to be relevant to opioid risk. The creation, refinement, and preliminary modeling of the item pool, establishment of preliminary concurrent validity, and the determination of the factor structure are presented. The initial development and validation of the Opioid Abuse Risk Screener shows promise for effective risk stratification.

  17. Sport i TV: Journalistik eller show?

    Directory of Open Access Journals (Sweden)

    Niels Kayser Nielsen

    1992-08-01

    Full Text Available De står i konkurrenceforhold til hinanden: De har tilsyneladende intet med hinanden at gøre. Men som seer er man ikke i tvivl: der er tale om en sjæl- den grad af afhængighed, hvor begge parter konstant seer og lytter til hin- anden. Det to parter er sporten i henholdsvis DR-TV og TV2. Men hvori består nu forskellene - og lighederne - mellem de to kanalers sportsud- sendelser? Hvilke behov kommer udsendelserne i møde? Hvilken betyd- ning produceres i disse udsendelser? Hvilke behov kommer udsendel- serne i møde? Hvilke traditioner for sportsformidling ligger man i forlæng- else af, og hvilke nyskabelser er der tale om? Hvorledes forholder det sig til udviklingen inden for sportens verden? Det er nogle af de spørgsmål, der trænger sig på - samman med en nærmere analyse af, hvad der på et mere detaljeret plan kendetegner præsentationsformen i sportsudsend- elserne i DR-TV og TV2.

  18. Archaea Signal Recognition Particle Shows the Way

    Directory of Open Access Journals (Sweden)

    Christian Zwieb

    2010-01-01

    Full Text Available Archaea SRP is composed of an SRP RNA molecule and two bound proteins named SRP19 and SRP54. Regulated by the binding and hydrolysis of guanosine triphosphates, the RNA-bound SRP54 protein transiently associates not only with the hydrophobic signal sequence as it emerges from the ribosomal exit tunnel, but also interacts with the membrane-associated SRP receptor (FtsY. Comparative analyses of the archaea genomes and their SRP component sequences, combined with structural and biochemical data, support a prominent role of the SRP RNA in the assembly and function of the archaea SRP. The 5e motif, which in eukaryotes binds a 72 kilodalton protein, is preserved in most archaea SRP RNAs despite the lack of an archaea SRP72 homolog. The primary function of the 5e region may be to serve as a hinge, strategically positioned between the small and large SRP domain, allowing the elongated SRP to bind simultaneously to distant ribosomal sites. SRP19, required in eukaryotes for initiating SRP assembly, appears to play a subordinate role in the archaea SRP or may be defunct. The N-terminal A region and a novel C-terminal R region of the archaea SRP receptor (FtsY are strikingly diverse or absent even among the members of a taxonomic subgroup.

  19. Analytical Chemistry Core Capability Assessment - Preliminary Report

    Energy Technology Data Exchange (ETDEWEB)

    Barr, Mary E. [Los Alamos National Laboratory; Farish, Thomas J. [Los Alamos National Laboratory

    2012-05-16

    The concept of 'core capability' can be nebulous one. Even at a fairly specific level, where core capability equals maintaining essential services, it is highly dependent upon the perspective of the requestor. Samples are submitted to analytical services because the requesters do not have the capability to conduct adequate analyses themselves. Some requests are for general chemical information in support of R and D, process control, or process improvement. Many analyses, however, are part of a product certification package and must comply with higher-level customer quality assurance requirements. So which services are essential to that customer - just those for product certification? Does the customer also (indirectly) need services that support process control and improvement? And what is the timeframe? Capability is often expressed in terms of the currently utilized procedures, and most programmatic customers can only plan a few years out, at best. But should core capability consider the long term where new technologies, aging facilities, and personnel replacements must be considered? These questions, and a multitude of others, explain why attempts to gain long-term consensus on the definition of core capability have consistently failed. This preliminary report will not try to define core capability for any specific program or set of programs. Instead, it will try to address the underlying concerns that drive the desire to determine core capability. Essentially, programmatic customers want to be able to call upon analytical chemistry services to provide all the assays they need, and they don't want to pay for analytical chemistry services they don't currently use (or use infrequently). This report will focus on explaining how the current analytical capabilities and methods evolved to serve a variety of needs with a focus on why some analytes have multiple analytical techniques, and what determines the infrastructure for these analyses. This

  20. Do men and women show love differently in marriage?

    Science.gov (United States)

    Schoenfeld, Elizabeth A; Bredow, Carrie A; Huston, Ted L

    2012-11-01

    In Western societies, women are considered more adept than men at expressing love in romantic relationships. Although scholars have argued that this view of love gives short shrift to men's ways of showing love (e.g., Cancian, 1986; Noller, 1996), the widely embraced premise that men and women "love differently" has rarely been examined empirically. Using data collected at four time points over 13 years of marriage, the authors examined whether love is associated with different behaviors for husbands and wives. Multilevel analyses revealed that, counter to theoretical expectations, both genders were equally likely to show love through affection. But whereas wives expressed love by enacting fewer negative or antagonistic behaviors, husbands showed love by initiating sex, sharing leisure activities, and doing household work together with their wives. Overall, the findings indicate that men and women show their love in more nuanced ways than cultural stereotypes suggest.

  1. Online Italian fandoms of American TV shows

    Directory of Open Access Journals (Sweden)

    Eleonora Benecchi

    2015-06-01

    Full Text Available The Internet has changed media fandom in two main ways: it helps fans connect with each other despite physical distance, leading to the formation of international fan communities; and it helps fans connect with the creators of the TV show, deepening the relationship between TV producers and international fandoms. To assess whether Italian fan communities active online are indeed part of transnational online communities and whether the Internet has actually altered their relationship with the creators of the original text they are devoted to, qualitative analysis and narrative interviews of 26 Italian fans of American TV shows were conducted to explore the fan-producer relationship. Results indicated that the online Italian fans surveyed preferred to stay local, rather than using geography-leveling online tools. Further, the sampled Italian fans' relationships with the show runners were mediated or even absent.

  2. 2008 LHC Open Days Physics: the show

    CERN Document Server

    2008-01-01

    A host of events and activities await visitors to the LHC Open Days on 5 and 6 April. A highlight will be the physics shows funded by the European Physical Society (EPS), which are set to surprise and challenge children and adults alike! School children use their experience of riding a bicycle to understand how planets move around the sun (Copyright : Circus Naturally) Participating in the Circus Naturally show could leave a strange taste in your mouth! (Copyright : Circus Naturally) The Rino Foundation’s experiments with liquid nitrogen can be pretty exciting! (Copyright: The Rino Foundation)What does a bicycle have in common with the solar system? Have you ever tried to weigh air or visualise sound? Ever heard of a vacuum bazooka? If you want to discover the answers to these questions and more then come to the Physics Shows taking place at the CERN O...

  3. Analysing ESP Texts, but How?

    OpenAIRE

    Borza Natalia

    2015-01-01

    English as a second language (ESL) teachers instructing general English and English for specific purposes (ESP) in bilingual secondary schools face various challenges when it comes to choosing the main linguistic foci of language preparatory courses enabling non-native students to study academic subjects in English. ESL teachers intending to analyse English language subject textbooks written for secondary school students with the aim of gaining information about what bilingual secondary schoo...

  4. An extensible analysable system model

    DEFF Research Database (Denmark)

    Probst, Christian W.; Hansen, Rene Rydhof

    2008-01-01

    , this does not hold for real physical systems. Approaches such as threat modelling try to target the formalisation of the real-world domain, but still are far from the rigid techniques available in security research. Many currently available approaches to assurance of critical infrastructure security...... allows for easy development of analyses for the abstracted systems. We briefly present one application of our approach, namely the analysis of systems for potential insider threats....

  5. DebriSat Laboratory Analyses

    Science.gov (United States)

    2015-01-05

    Semiquantitative elemental composition. – Elemental mapping and line scans. • Fourier Transform Infrared ( FTIR ) spectroscopy – Identification of chemical...Transform Infrared ( FTIR ) spectroscopy – Nicolet 6700 spectrometer. – Harrick Scientific “praying mantis” diffuse reflectance accessory. • Qualitative...VIS-NIR Spectroscopy Dianna Alaan © The Aerospace Corporation 2015 DebriSat Laboratory Analyses 5 January, 2015 Paul M. Adams1, Zachary Lingley2

  6. Preliminary design of the Space Station internal thermal control system

    Science.gov (United States)

    Herrin, Mark T.; Patterson, David W.; Turner, Larry D.

    1987-01-01

    The baseline preliminary design configuration of the Internal Thermal Control system (ITCS) of the U.S. Space Station pressurized elements (i.e., the Habitation and U.S. Laboratory modules, pressurized logistics carrier, and resources nodes) is defined. The ITCS is composed of both active and passive components. The subsystems which comprise the ITCS are identified and their functional descriptions are provided. The significant trades and analyses, which were performed during Phase B (i.e., the preliminary design phase) that resulted in the design described herein, are discussed. The ITCS interfaces with the station's central Heat Rejection and Transport System (HRTS), other systems, and externally attached pressurized payloads are described. Requirements on the ITCS with regard to redundancy and experiment support are also addressed.

  7. Liquid Crystal Research Shows Deformation By Drying

    Science.gov (United States)

    2003-01-01

    These images, from David Weitz's liquid crystal research, show ordered uniform sized droplets (upper left) before they are dried from their solution. After the droplets are dried (upper right), they are viewed with crossed polarizers that show the deformation caused by drying, a process that orients the bipolar structure of the liquid crystal within the droplets. When an electric field is applied to the dried droplets (lower left), and then increased (lower right), the liquid crystal within the droplets switches its alignment, thereby reducing the amount of light that can be scattered by the droplets when a beam is shone through them.

  8. Mitogenomic analyses of eutherian relationships.

    Science.gov (United States)

    Arnason, U; Janke, A

    2002-01-01

    Reasonably correct phylogenies are fundamental to the testing of evolutionary hypotheses. Here, we present phylogenetic findings based on analyses of 67 complete mammalian mitochondrial (mt) genomes. The analyses, irrespective of whether they were performed at the amino acid (aa) level or on nucleotides (nt) of first and second codon positions, placed Erinaceomorpha (hedgehogs and their kin) as the sister group of remaining eutherians. Thus, the analyses separated Erinaceomorpha from other traditional lipotyphlans (e.g., tenrecs, moles, and shrews), making traditional Lipotyphla polyphyletic. Both the aa and nt data sets identified the two order-rich eutherian clades, the Cetferungulata (comprising Pholidota, Carnivora, Perissodactyla, Artiodactyla, and Cetacea) and the African clade (Tenrecomorpha, Macroscelidea, Tubulidentata, Hyracoidea, Proboscidea, and Sirenia). The study corroborated recent findings that have identified a sister-group relationship between Anthropoidea and Dermoptera (flying lemurs), thereby making our own order, Primates, a paraphyletic assembly. Molecular estimates using paleontologically well-established calibration points, placed the origin of most eutherian orders in Cretaceous times, 70-100 million years before present (MYBP). The same estimates place all primate divergences much earlier than traditionally believed. For example, the divergence between Homo and Pan is estimated to have taken place approximately 10 MYBP, a dating consistent with recent findings in primate paleontology.

  9. MicroRNAs show diverse and dynamic expression patterns in multiple tissues of Bombyx mori

    Directory of Open Access Journals (Sweden)

    Xiang Zhonghuai

    2010-02-01

    Full Text Available Abstract Background MicroRNAs (miRNAs repress target genes at the post-transcriptional level, and function in the development and cell-lineage pathways of host species. Tissue-specific expression of miRNAs is highly relevant to their physiological roles in the corresponding tissues. However, to date, few miRNAs have been spatially identified in the silkworm. Results We establish for the first time the spatial expression patterns of nearly 100 miRNAs in multiple normal tissues (organs of Bombyx mori females and males using microarray and Northern-blotting analyses. In all, only 10 miRNAs were universally distributed (including bmo-let-7 and bmo-bantam, while the majority were expressed exclusively or preferentially in specific tissue types (e.g., bmo-miR-275 and bmo-miR-1. Additionally, we examined the developmental patterns of miRNA expression during metamorphosis of the body wall, silk glands, midgut and fat body. In total, 63 miRNAs displayed significant alterations in abundance in at least 1 tissue during the developmental transition from larvae to pupae (e.g., bmo-miR-263b and bmo-miR-124. Expression patterns of five miRNAs were significantly increased during metamorphosis in all four tissues (e.g., bmo-miR-275 and bmo-miR-305, and two miRNA pairs, bmo-miR-10b-3p/5p and bmo-miR-281-3p/5p, showed coordinate expression. Conclusions In this study, we conducted preliminary spatial measurements of several miRNAs in the silkworm. Periods of rapid morphological change were associated with alterations in miRNA expression patterns in the body wall, silk glands, midgut and fat body during metamorphosis. Accordingly, we propose that corresponding ubiquitous or tissue-specific expression of miRNAs supports their critical roles in tissue specification. These results should facilitate future functional analyses.

  10. A Talk Show from the Past.

    Science.gov (United States)

    Gallagher, Arlene F.

    1991-01-01

    Describes a two-day activity in which elementary students examine voting rights, the right to assemble, and women's suffrage. Explains the game, "Assemble, Reassemble," and a student-produced talk show with five students playing the roles of leaders of the women's suffrage movement. Profiles Elizabeth Cady Stanton, Lucretia Mott, Susan…

  11. The Last Great American Picture Show

    NARCIS (Netherlands)

    Elsaesser, Thomas; King, Noel; Horwath, Alexander

    2004-01-01

    The Last Great American Picture Show brings together essays by scholars and writers who chart the changing evaluations of the American cinema of the 1970s, sometimes referred to as the decade of the lost generation, but now more and more recognized as the first New Hollywood, without which the cinem

  12. Gene Therapy Shows Promise for Aggressive Lymphoma

    Science.gov (United States)

    ... page: https://medlineplus.gov/news/fullstory_163824.html Gene Therapy Shows Promise for Aggressive Lymphoma Over one-third ... TUESDAY, Feb. 28, 2017 (HealthDay News) -- An experimental gene therapy for aggressive non-Hodgkin lymphoma beat back more ...

  13. Development, management and economy of show caves.

    Directory of Open Access Journals (Sweden)

    Cigna Arrigo A.

    2000-01-01

    Full Text Available The problems concerning the development of show caves are here considered by taking into account different aspects of the problem. A procedure to carry out an Environmental Impact Assessment (EIA has been established in the last decade and it is now currently applied. Such an assessment starts with a pre-operational phase to obtain sufficient information on the undisturbed status of a cave to be developed into a show cave. Successively a programme for its development is established with the scope to optimise the intervention on the cave at the condition that its basic environmental parameters are not irreversibly modified. The last phase of the assessment is focussed to assure a feedback through a monitoring network in order to detect any unforeseen difference or anomaly between the project and the effective situation achieved after the cave development. Some data on some of the most important show caves in the world are reported and a tentative evaluation of the economy in connection with the show caves business is eventually made.

  14. Show Them You Really Want the Job

    Science.gov (United States)

    Perlmutter, David D.

    2012-01-01

    Showing that one really "wants" the job entails more than just really wanting the job. An interview is part Broadway casting call, part intellectual dating game, part personality test, and part, well, job interview. When there are 300 applicants for a position, many of them will "fit" the required (and even the preferred) skills listed in the job…

  15. TV-Show Retrieval and Classification

    NARCIS (Netherlands)

    Musto, C.; Narducci, F.; Lops, P.; Semeraro G.; Gemmis, M. de; Barbieri, M.; Korst, J.H.M.; Pronk, S.P.P.; Clout, R.A.W.

    2012-01-01

    Recommender systems are becoming popular tools to aid users in finding interesting and relevant TV-shows and other digital video assets,based on implicitly learned user preferences. In this context, a common assumption is that user preferences can be specified by program types (movie, sports, ...) a

  16. The British Show in Australia, 1985

    Directory of Open Access Journals (Sweden)

    Anthony Bond

    2016-07-01

    Full Text Available In 1984–85, The British Show, an exhibition largely made up of New British Sculpture, was curated for Australia and New Zealand. This essay discusses the context and effects of the exhibition on art in Australia. It also seeks to define the sources of originality and innovation of the artists included.

  17. Laser entertainment and light shows in education

    Science.gov (United States)

    Sabaratnam, Andrew T.; Symons, Charles

    2002-05-01

    Laser shows and beam effects have been a source of entertainment since its first public performance May 9, 1969, at Mills College in Oakland, California. Since 1997, the Photonics Center, NgeeAnn Polytechnic, Singapore, has been using laser shows as a teaching tool. Students are able to exhibit their creative skills and learn at the same time how lasers are used in the entertainment industry. Students will acquire a number of skills including handling three- phase power supply, operation of cooling system, and laser alignment. Students also acquire an appreciation of the arts, learning about shapes and contours as they develop graphics for the shows. After holography, laser show animation provides a combination of the arts and technology. This paper aims to briefly describe how a krypton-argon laser, galvanometer scanners, a polychromatic acousto-optic modulator and related electronics are put together to develop a laser projector. The paper also describes how students are trained to make their own laser animation and beam effects with music, and at the same time have an appreciation of the operation of a Class IV laser and the handling of optical components.

  18. Analysing Interplanetary Probe Guidance Accuracy

    Directory of Open Access Journals (Sweden)

    S. V. Sukhova

    2016-01-01

    Full Text Available The paper presents a guidance accuracy analysis and estimates delta-v budget required to provide the trajectory correction maneuvers for direct interplanetary flights (without midcourse gravity assists. The analysis takes into consideration the orbital hyperbolic injection errors (depend on a selected launch vehicle and ascent trajectory and the uncertainties of midcourse correction maneuvers.The calculation algorithm is based on Monte Carlo simulation and Danby’s matrix methods (the matrizant of keplerian motion. Danby’s method establishes a link between the errors of the spacecraft state vectors at different flight times using the reference keplerian orbit matrizant. Utilizing the nominal trajectory parameters and the covariance matrix of launch vehicle injection errors the random perturbed orbits are generated and required velocity corrections are calculated. The next step is to simulate midcourse maneuver performance uncertainty using the midcourse maneuver covariance matrix. The obtained trajectory correction impulses and spacecraft position errors are statistically processed to compute required delta-v budget and dispersions ellipse parameters for different prediction intervals.As an example, a guidance accuracy analysis has been conducted for a 2022 mission to Mars and a Venus mission in 2026. The paper considers one and two midcourse correction options, as well as utilization of two different launch vehicles.The presented algorithm based on Monte Carlo simulation and Danby’s methods provides preliminary evaluation for midcourse corrections delta-v budget and spacecraft position error. The only data required for this guidance accuracy analysis are a reference keplerian trajectory and a covariance matrix of the injection errors. Danby’s matrix method allows us to take into account also the other factors affecting the trajectory thereby increasing the accuracy of analysis.

  19. DMPD: Structural and functional analyses of bacterial lipopolysaccharides. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 12106784 Structural and functional analyses of bacterial lipopolysaccharides. Carof...html) (.csml) Show Structural and functional analyses of bacterial lipopolysaccharides. PubmedID 12106784 Ti...tle Structural and functional analyses of bacterial lipopolysaccharides. Authors

  20. La mujer, en los talk shows

    Directory of Open Access Journals (Sweden)

    Antrop. José Gamboa Cetina

    2001-01-01

    Full Text Available Dentro de los medios de comunicación, uno de los que más ha impactado a la población latinoamericana ha sido la televisión, y en la barra programática de las televisoras ha surgido un tipo de programas denominados talk shows. En los últimos meses, la sociedad mexicana ha vivido el "boom" de los talk shows, que en poco tiempo han saturado la barra de la programación vespertina de las dos principales empresas televisivas de la república mexicana. Este fenómeno puede estudiarse desde diversas perspectivas. Sin embargo, por motivos de espacio, en esta ocasión analizaremos su impacto en las mujeres, desde diferentes dimensiones.

  1. 2009 Hands Across Pacific Show Held

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    <正>The 2009 Hands Across the Pacific Show co-sponsored by the Canadian International Cultural Exchanges (CICEX) and Hunan Provincial People’s Association for Friendship with Foreign Countries(HPPAFFC) was held respectively in the Tower Hall of Tokyo,Japan from July 2 to 7 and in the Hunan Provincial Museum from August 1 to 5.Jing Dunquan,Vice President of the

  2. The People's Show: A Critical Analysis

    OpenAIRE

    Robin Francis

    1996-01-01

    The 1990s heralded a new form of museum exhibition: "The People's Show." A light-hearted celebration of popular culture, the concept has had phenomenal success throughout the United Kingdom. Beneath the humour, however, are more complex and radical agendas relating to cultural rights. The paper explores the issues associated with the rise and possible wane of this museum-based popular cultural phenomenon.

  3. Reality, ficción o show

    Directory of Open Access Journals (Sweden)

    Sandra Ruíz Moreno

    2002-01-01

    Full Text Available Para tener un punto de vista claro y objetivo frente a la polémica establecida en torno al programa “Protagonistas de novela” y la tendiente proliferación de los reality show en las parrillas de programación de la televisión colombiana, se realizó un análisis de texto y contenido de dicho programa, intentando definirlo desde sus posibilidades de realidad, ficción y show. Las unidades de análisis y el estudio de su tratamiento arrojaron un alto contenido que gira en torno a las emociones del ser humano relacionadas con la convivencia, tratadas a manera de show y con algunos aportes textuales de ficción, pero sin su elemento mediador básico, el actor, quitándole toda la posibilidad de tener un tratamiento con la profundidad, distancia y ética que requieren los temas de esta índole. El resultado es un formato que sólo busca altos índices de sintonía y que pertenece más a la denominada televisión “trash”, que a una búsqueda de realidad del hombre y mucho menos de sociedad.

  4. Preliminary psychometric validation of the Polish version of the EORTC elderly module (QLQ-ELD14).

    Science.gov (United States)

    Wrazen, Waldemar; Golec, Edward B; Tomaszewska, Iwona M; Walocha, Ewa; Dudkiewicz, Zbigniew; Tomaszewski, Krzysztof A

    2014-01-01

    The aim of our study was to report preliminary validation data on the EORTC translated, Polish version of the EORTC QLQ-ELD14 questionnaire to show that this tool is an acceptable and psychometrically robust measure to collect HRQoL data in Polish elderly patients with cancer. Patients with histological confirmation of primary cancer were eligible for the study. All patients filled out the Polish version of the EORTC QLQ-ELD14 module in addition to EORTC QLQ-C30 and a demographic questionnaire. Standardized validity and reliability analyses were performed. Sixty-five patients (41 females - 63.1%) were enrolled into the study, with a mean age of 76.4 ± 5.7 years. Cronbach alpha coefficients, range 0.70-0.84, showed positive internal consistency. Satisfactory convergent and discriminant validity in multi-trait scaling analyses was seen. Strong correlations were observed between the EORTC QLQ-ELD14 (especially mobility and burden of illness), and the EORTC QLQ-C30 (r = -0.30-(-0.83); p EORTC QLQ-ELD14 module is a reliable and valid tool for measuring HRQoL in elderly cancer patients. However further research is needed to establish the full psychometric properties of the described module, especially in regards to test-retest and responsiveness over time.

  5. Analyses of a Virtual World

    CERN Document Server

    Holovatch, Yurij; Szell, Michael; Thurner, Stefan

    2016-01-01

    We present an overview of a series of results obtained from the analysis of human behavior in a virtual environment. We focus on the massive multiplayer online game (MMOG) Pardus which has a worldwide participant base of more than 400,000 registered players. We provide evidence for striking statistical similarities between social structures and human-action dynamics in the real and virtual worlds. In this sense MMOGs provide an extraordinary way for accurate and falsifiable studies of social phenomena. We further discuss possibilities to apply methods and concepts developed in the course of these studies to analyse oral and written narratives.

  6. [Laboratory analyses in sports medicine].

    Science.gov (United States)

    Clénin, German E; Cordes, Mareike

    2015-05-01

    Laboratory analyses in sports medicine are relevant for three reasons: 1. In actively exercising individuals laboratory analysis are one of the central elements in the diagnosis of diseases and overreaching. 2. Regularly done laboratory analysis in competitive athletes with high load of training and competition may help to detect certain deficiencies early on. 3. Physical activity in general and competitive exercise training specifically do change certain routine laboratory parameters significantly although not reflecting pathological changes. These so-called preanalytic variations should be taken into consideration while interpreting laboratory data in medical emergency and routine diagnostics. This article intends to help the physician to interprete laboratory data of actively exercising sportsmen.

  7. Bite my art to show your love

    OpenAIRE

    Kim, Hye yeon

    2012-01-01

    Two years ago, I came to the States for MFA program in UCSD. At first, I started making instructions for performance to communicate with people in my clumsy English, but it soon became my general process of working. In this show, I present a room surrounded by five video projections and drawings. They are documentation of performances concerning the balance of relationship. I performed two with Josh Aaron, other two with Josh Tonies, and one by myself. The performance done by myself reveals t...

  8. Showing and Saying. An Aesthetic Difference

    Directory of Open Access Journals (Sweden)

    Vicente Sanfélix Vidarte

    2013-05-01

    Full Text Available Wittgenstein’s distinction between saying and showing and the associated thesis, what can be shown cannot be said, were crucial to his first philosophy, persisted throughout the evolution of his whole thought and played a key role in his views on aesthetics. The objective of art is access to the mystical, forcing us to become aware of the uniqueness of our own experience and life. When art is good is a perfect expression and the work of art becomes like a tautology. An important consequence of this understanding of art is the irreducibility of the aesthetic to the scientific perspective.

  9. Latest European coelacanth shows Gondwanan affinities.

    Science.gov (United States)

    Cavin, Lionel; Forey, Peter L; Buffetaut, Eric; Tong, Haiyan

    2005-06-22

    The last European fossil occurrence of a coelacanth is from the Mid-Cretaceous of the English Chalk (Turonian, 90 million years ago). Here, we report the discovery of a coelacanth from Late Cretaceous non-marine rocks in southern France. It consists of a left angular bone showing structures that imply close phylogenetic affinities with some extinct Mawsoniidae. The closest relatives are otherwise known from Cretaceous continental deposits of southern continents and suggest that the dispersal of freshwater organisms from Africa to Europe occurred in the Late Cretaceous.

  10. Abbreviated Goal Management Training Shows Preliminary Evidence as a Neurorehabilitation Tool for HIV-associated Neurocognitive Disorders among Substance Users

    Science.gov (United States)

    Casaletto, Kaitlin B.; Moore, David J.; Woods, Steven Paul; Umlauf, Anya; Scott, J. C.; Heaton, Robert K.

    2016-01-01

    Objective Substance use disorders are highly comorbid with and contribute to the increased prevalence of neurocognitive dysfunction observed in HIV infection. Despite their adverse impact on everyday functioning, there are currently no compensatory-based neurorehabilitation interventions validated for use among HIV+ substance users (HIV/SUD). This study examined the effectiveness of Goal Management Training (GMT) alone or GMT as part of a metacognitive training among HIV/SUD individuals with executive dysfunction. Methods Ninety HIV/SUD individuals were randomized to a single 15-minute session: 1) GMT (n=30); 2) GMT plus metacognitive training (neurocognitive awareness; GMT+Meta; n=30); or 3) active control (n=30). Following a brief neurocognitive battery and study condition, participants performed a complex laboratory-based function task, Everyday Multitasking Test (Everyday MT), during which metacognition (awareness) was evaluated. Results There was an increasing, but nonsignificant tendency for better Everyday MT performances across study conditions (Control≤GMT≤GMT+Meta; psmetacognitive task appraisals as compared to the control condition. Among participants who underwent GMT, benefits were most prominent in persons with poorer pre-training dual-tasking ability, depression, and methamphetamine use disorders (ds=0.35–1.04). Conclusions A brief compensatory strategy has benefits for everyday multitasking and metacognition among HIV+ substance users with executive dysfunction. Future work exploring more intensive trainings, potentially complimentary to other restorative approaches and/or pharmacological treatments, is warranted. PMID:26753986

  11. Preliminary Requirement of Hot Pool Free Surface Level from PGSFR Reactor Head

    Energy Technology Data Exchange (ETDEWEB)

    Koo, Gyeonghoi; Joo, Hyeongkook [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-05-15

    The sensitivity study on structural integrity evaluations are carried out to make a decision of a hot pool free surface location from the reactor head for a preliminary designed reactor enclosure system. To do this, the thermal stress evaluations for a reactor vessel are carried out for a steady state normal operating condition with detailed heat transfer analyses through the reactor enclosure system. From these results, the preliminary design requirement of a hot pool free surface location from the reactor head is established to be 2.0m. From the sensitivity studies on the structural integrity evaluations for a steady state condition, the preliminary distance from the hot pool free surface to the reactor head is determined to be 2.0m same as a conceptual design. More detailed structural analyses for a reactor enclosure system will be carried out as a PGSFR structural design goes forward in detail.

  12. THOR Turbulence Electron Analyser: TEA

    Science.gov (United States)

    Fazakerley, Andrew; Moore, Tom; Owen, Chris; Pollock, Craig; Wicks, Rob; Samara, Marilia; Rae, Jonny; Hancock, Barry; Kataria, Dhiren; Rust, Duncan

    2016-04-01

    Turbulence Heating ObserveR (THOR) is the first mission ever flown in space dedicated to plasma turbulence. The Turbulence Electron Analyser (TEA) will measure the plasma electron populations in the mission's Regions of Interest. It will collect a 3D electron velocity distribution with cadences as short as 5 ms. The instrument will be capable of measuring energies up to 30 keV. TEA consists of multiple electrostatic analyser heads arranged so as to measure electrons arriving from look directions covering the full sky, i.e. 4 pi solid angle. The baseline concept is similar to the successful FPI-DES instrument currently operating on the MMS mission. TEA is intended to have a similar angular resolution, but a larger geometric factor. In comparison to earlier missions, TEA improves on the measurement cadence. For example, MMS FPI-DES routinely operates at 30 ms cadence. The objective of measuring distributions at rates as fast as 5 ms is driven by the mission's scientific requirements to resolve electron gyroscale size structures, where plasma heating and fluctuation dissipation is predicted to occur. TEA will therefore be capable of making measurements of the evolution of distribution functions across thin (a few km) current sheets travelling past the spacecraft at up to 600 km/s, of the Power Spectral Density of fluctuations of electron moments and of distributions fast enough to match frequencies with waves expected to be dissipating turbulence (e.g. with 100 Hz whistler waves).

  13. Figure of Beijing ABP Showing up

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ Last year, there were many good news from Beijing Advanced Business Park(ABP): on October 29, 2005, Xu Weiping, Chairman of the Board of ABP, was chosen as the"2005 Ten Major Chinese Administrative Person in News";On November 8,2005,CCIM (American Certified Commercial Investment Member) invited 40 world famous real estate investors to visit ABS and they showed will to cooperate; On November 22, 2005, Johnson Controls, Inc., one of World Top 500, signed the contract with Zhongguan Village Fengtai Garden that the headquarter of JCI energy administration China Branch will move to ABP to improve the energy administration and radiate all the nation; on December 10,2005, "CEO Salon" co-organized by Phoenix Satellite Television and ABP, was held in the meeting room of ABP, over 120CEOs met here to discuss the trend of China economic development and the development opportunities brought by 11th Five-Year Plan for enterprises.

  14. Lemurs and macaques show similar numerical sensitivity

    Science.gov (United States)

    Jones, Sarah M.; Pearson, John; DeWind, Nicholas K.; Paulsen, David; Tenekedjieva, Ana-Maria; Brannon, Elizabeth M.

    2013-01-01

    We investigated the precision of the approximate number system (ANS) in three lemur species (Lemur catta, Eulemur mongoz, and Eulemur macaco flavifrons), one Old World monkey species (Macaca mulatta) and humans (Homo sapiens). In Experiment 1, four individuals of each nonhuman primate species were trained to select the numerically larger of two visual arrays on a touchscreen. We estimated numerical acuity by modeling Weber fractions (w) and found quantitatively equivalent performance among all four nonhuman primate species. In Experiment 2, we tested adult humans in a similar procedure, and they outperformed the four nonhuman species but showed qualitatively similar performance. These results indicate that the ANS is conserved over the primate order. PMID:24068469

  15. Star Shows It Has The Right Stuff

    Science.gov (United States)

    2004-01-01

    Astronomers have used an observation by NASA's Chandra X-ray Observatory to make the best case yet that a star can be engulfed by its companion star and survive. This discovery will help astronomers better understand how closely coupled stars, and perhaps even stars and planets, evolve when one of the stars expands enormously in its red giant phase. The binary star system known as V471 Tauri comprises a white dwarf star (the primary) in a close orbit -- one thirtieth of the distance between Mercury and the Sun -- with a normal Sun-like star (the secondary). Chandra's data showed that the hot upper atmosphere of the secondary star has a deficit of carbon atoms relative to nitrogen atoms. "This deficit of carbon atoms is the first clear observational evidence that the normal star was engulfed by its companion in the past," according to Jeremy Drake of the Smithsonian Astrophysical Observatory in Cambridge, MA, who coauthored an article on V471 in The Astrophysical Journal Letters with Marek Sarna of the N. Copernicus Astronomical Center in Poland. The white dwarf star was once a star several times as massive as the Sun. Nuclear fusion reactions in the core of such a star convert carbon into nitrogen over a period of about a billion years. When the fuel in the core of the star is exhausted, the core collapses, triggering more energetic nuclear reactions that cause the star to expand and transform into a red giant before eventually collapsing to become a white dwarf. The carbon-poor material in the core of the red giant is mixed with outer part of the star, so its atmosphere shows a deficit of carbon, as compared with Sun-like stars. The X-ray spectra of a red giant star (top panel) and a Sun-like star (bottom panel) show the large difference in the peaks due to carbon atoms in the two stars. Theoretical calculations indicate that a red giant in a binary system can completely envelop its companion star and dramatically affect its evolution. During this common envelope

  16. Ancient bacteria show evidence of DNA repair

    DEFF Research Database (Denmark)

    Johnson, Sarah Stewart; Hebsgaard, Martin B; Christensen, Torben R

    2007-01-01

    Recent claims of cultivable ancient bacteria within sealed environments highlight our limited understanding of the mechanisms behind long-term cell survival. It remains unclear how dormancy, a favored explanation for extended cellular persistence, can cope with spontaneous genomic decay over......-term survival of bacteria sealed in frozen conditions for up to one million years. Our results show evidence of bacterial survival in samples up to half a million years in age, making this the oldest independently authenticated DNA to date obtained from viable cells. Additionally, we find strong evidence...... that this long-term survival is closely tied to cellular metabolic activity and DNA repair that over time proves to be superior to dormancy as a mechanism in sustaining bacteria viability....

  17. Hellenic Amateur Astronomy Association's activities: Preliminary results on Perseids 2010

    Science.gov (United States)

    Maravelias, G.

    2011-01-01

    Preliminary results on the Perseids 2010 are presented. Visual and video observations were obtained by the author and a first reduction of the visual data shows that a maximum of ZHR ~120 was reached during the night 12-13 of August 2010. Moreover, a video setup was tested (DMK camera and UFO Capture v2) and the results show that, under some limitations, valuable data can be obtained.

  18. EPA Releases the First of Four Preliminary Risk Assessments for Insecticides Potentially Harmful to Bees

    Science.gov (United States)

    WASHINGTON-- The U.S. Environmental Protection Agency (EPA) announced a preliminary pollinator risk assessment for the neonicotinoid insecticide, imidacloprid, which shows a threat to some pollinators. EPA's assessment, prepared in collaboration wit

  19. Finite element modelling of the tricuspid valve: A preliminary study.

    Science.gov (United States)

    Stevanella, Marco; Votta, Emiliano; Lemma, Massimo; Antona, Carlo; Redaelli, Alberto

    2010-12-01

    The incomplete efficacy of current surgical repair procedures of the tricuspid valve (TV) demands a deeper comprehension of the physiological TV biomechanics. To this purpose, computational models can provide quantitative insight into TV biomechanical response and allow analysing the role of each TV substructure. We present here a three-dimensional finite element model of the tricuspid valve that takes into account most of its peculiar features. Experimental measurements were performed on human and porcine valves to obtain a more detailed TV anatomical framework. To overcome the complete lack of information on leaflets mechanical properties, we performed a sensitivity analysis on the parameters of the adopted non-linear hyperelastic constitutive model, hypothesizing three different parameter sets for three significant collagen fibre distributions. Results showed that leaflets' motion and maximum principal stress distribution were almost insensitive to the different material parameters considered. Highest stresses (about 100kPa) were located near the annulus of the anterior and septal leaflets, while the posterior leaflet experienced lower stresses (about 55kPa); stresses at the commissures were nearly zero. Conversely, changes in constitutive parameters deeply affected leaflets' strains magnitude, but not their overall pattern. Strains computed assuming that TV leaflets tissue are reinforced by a sparse and loosely arranged network of collagen fibres fitted best experimental data, thus suggesting that this may be the actual microstructure of TV leaflets. In a long-term perspective, this preliminary study aims at providing a starting point for the development of a predictive tool to quantitatively evaluate TV diseases and surgical repair procedures.

  20. Failure of Magnetic Fluid Seals Operating in Water: Preliminary Conclusions

    Directory of Open Access Journals (Sweden)

    Matuszewski Leszek

    2017-06-01

    Full Text Available The article analyses properties of magnetic fluid seals installed in rotary sealing nodes which operate in the utility water environment. Seals of this type have been examined as a possible solution to the problem with ship manoeuvring propulsion sealing. The present analysis bases on laboratory durability tests of magnetic fluid seals exposed to longterm utility water loads, at different water pressures and shaft revolutions. The basic seal durability criterion was the number of revolutions made by the sealing node shaft until the appearance of water tightness loss (leakage. It was found that the main factor leading to the wear of the seal is the relative speed of the magnetic fluid with respect to that of the utility water, and this process is heavily affected by the pressure acting on the seal. The reported test results are presented in the form of diagrams showing the seal durability (time until water tightness loss as a function of rotational speed. The curves shown in the diagrams are regular, with two different rotational speed ranges: the highspeed range, when the tightness loss is relatively fast, and the low-speed range, with a clear tendency to prolong the seal lifetime. These diagrams were given the name of durability curves of the MF seal operating in water. The results of the performed tests suggest formal similarity between the experimental data distribution concerning tightness loss processes occurring in magnetic fluid seals operating in water environment and metal fatigue processes. The article proposes a preliminary simplified durability model to describe the examined phenomenon.

  1. A preliminary magnetic study of Sawa lake sediments, Southern Iraq

    Science.gov (United States)

    Ameen, Nawrass

    2016-04-01

    A preliminary magnetic study combined with chemical analyses was carried out in Sawa Lake in Al-Muthanna province, southern Iraq, about 22 km south west of Samawa city (31°18'48.80"N, 45°0'25.25"E). The lake is about 4.74 km length, 1.75 km width and 5.5 m height, it is surrounded by a salt rim which is higher than the lake water by about 2.8 m and sea water by about 18.5 m (Naqash et al., 1977 in Hassan, 2007). The lake is an elongated closed basin with no surface water available to it, it may be fed by groundwater of the Euphrates and Dammam aquifers through system of joints and cracks. This study aims to investigate the concentrations of selected heavy metals as pollutants and magnetic susceptibility (MS) and other magnetic properties of sediment samples from fifty sites collected from the bottom of the lake, the study area lies in an industrial area. The results show spatial variations of MS with mean value of about 4.58 x 10-8 m3 kg-1. Scanning electron microscopy and magnetic mineralogy parameters indicate the dominance of soft magnetic phase like magnetite and presence of hard magnetic phase like hematite. Spatial variations of MS combined with the concentrations of heavy metals suggests the efficiency of magnetic methods as effective, inexpensive and non-time consuming method to outlining the heavy metal pollution. References: Hassan W.F., 2007. The Physio-chemical characteristic of Sawa lake water in Samawa city-Iraq. Marine Mesopotamica, 22(2), 167-179.

  2. Analysing ESP Texts, but How?

    Directory of Open Access Journals (Sweden)

    Borza Natalia

    2015-03-01

    Full Text Available English as a second language (ESL teachers instructing general English and English for specific purposes (ESP in bilingual secondary schools face various challenges when it comes to choosing the main linguistic foci of language preparatory courses enabling non-native students to study academic subjects in English. ESL teachers intending to analyse English language subject textbooks written for secondary school students with the aim of gaining information about what bilingual secondary school students need to know in terms of language to process academic textbooks cannot avoiding deal with a dilemma. It needs to be decided which way it is most appropriate to analyse the texts in question. Handbooks of English applied linguistics are not immensely helpful with regard to this problem as they tend not to give recommendation as to which major text analytical approaches are advisable to follow in a pre-college setting. The present theoretical research aims to address this lacuna. Respectively, the purpose of this pedagogically motivated theoretical paper is to investigate two major approaches of ESP text analysis, the register and the genre analysis, in order to find the more suitable one for exploring the language use of secondary school subject texts from the point of view of an English as a second language teacher. Comparing and contrasting the merits and limitations of the two contrastive approaches allows for a better understanding of the nature of the two different perspectives of text analysis. The study examines the goals, the scope of analysis, and the achievements of the register perspective and those of the genre approach alike. The paper also investigates and reviews in detail the starkly different methods of ESP text analysis applied by the two perspectives. Discovering text analysis from a theoretical and methodological angle supports a practical aspect of English teaching, namely making an informed choice when setting out to analyse

  3. Translation of the Manchester Clinical Supervision Scale (MCSS) into Danish and a preliminary psychometric validation

    DEFF Research Database (Denmark)

    Buus, Niels; Gonge, Henrik

    2013-01-01

    for the translation of the MCSS from English into Danish and to present a preliminary psychometric validation of the Danish version of the scale. Methods included a formal translation/back-translation procedure and statistical analyses. The sample consisted of MCSS scores from 139 Danish mental health nursing staff...

  4. Proteins analysed as virtual knots

    CERN Document Server

    Alexander, Keith; Dennis, Mark R

    2016-01-01

    Long, flexible physical filaments are naturally tangled and knotted, from macroscopic string down to long-chain molecules. The existence of knotting in a filament naturally affects its configuration and properties, and may be very stable or disappear rapidly under manipulation and interaction. Knotting has been previously identified in protein backbone chains, for which these mechanical constraints are of fundamental importance to their molecular functionality, despite their being open curves in which the knots are not mathematically well defined; knotting can only be identified by closing the termini of the chain somehow. We introduce a new method for resolving knotting in open curves using virtual knots, a wider class of topological objects that do not require a classical closure and so naturally capture the topological ambiguity inherent in open curves. We describe the results of analysing proteins in the Protein Data Bank by this new scheme, recovering and extending previous knotting results, and identify...

  5. Retorisk analyse af historiske tekster

    DEFF Research Database (Denmark)

    Kock, Christian Erik J

    2014-01-01

    In recent years, rhetoric and the rhetorical tradition has attracted increasing interest from historians, such as, e.g., Quentin Skinner. The paper aims to explain and illustrate what may be understood by a rhetorical analysis (or “rhetorical criticism”) of historical documents, i.e., how those...... scholars who identify themselves as rhetoricians tend to define and conduct such an analysis. It is argued that while rhetoricians would sympathize with Skinner’s adoption of speech act theory in his reading of historical documents, they would generally extend their rhetorical readings of such documents...... to many more features than just the key concepts invoked in them. The paper discusses examples of rhetorical analyses done by prominent contemporary rhetoricians, including Edwin Black, Kenneth Burke, Maurice Charland, and Michael Leff. It relates its view of rhetorical documents to trends in current...

  6. HGCal Simulation Analyses for CMS

    CERN Document Server

    Bruno, Sarah Marie

    2015-01-01

    This summer, I approached the topic of fast-timing detection of photons from Higgs decays via simulation analyses, working under the supervision of Dr. Adolf Bornheim of the California Institute of Technology. My specific project focused on simulating the high granularity calorimeter for the Compact Muon Solenoid (CMS) experiment. CMS detects particles using calorimeters. The Electromagnetic Calorimeter (ECal) is arranged cylindrically to form a barrel section and two “endcaps.” Previously, both the barrel and endcap have employed lead tungstate crystal detectors, known as the “shashlik” design. The crystal detectors, however, rapidly degrade from exposure to radiation. This effect is most pronounced in the endcaps. To avoid the high expense of frequently replacing degraded detectors, it was recently decided to eliminate the endcap crystals in favor of an arrangement of silicon detectors known as the “High Granularity Calorimeter” (HGCal), while leaving the barrel detector technology unchanged. T...

  7. Analysing performance through value creation

    Directory of Open Access Journals (Sweden)

    Adrian TRIFAN

    2015-12-01

    Full Text Available This paper draws a parallel between measuring financial performance in 2 variants: the first one using data offered by accounting, which lays emphasis on maximizing profit, and the second one which aims to create value. The traditional approach to performance is based on some indicators from accounting data: ROI, ROE, EPS. The traditional management, based on analysing the data from accounting, has shown its limits, and a new approach is needed, based on creating value. The evaluation of value based performance tries to avoid the errors due to accounting data, by using other specific indicators: EVA, MVA, TSR, CVA. The main objective is shifted from maximizing the income to maximizing the value created for shareholders. The theoretical part is accompanied by a practical analysis regarding the creation of value and an analysis of the main indicators which evaluate this concept.

  8. Analysing the Wrongness of Killing

    DEFF Research Database (Denmark)

    Di Nucci, Ezio

    2014-01-01

    This article provides an in-depth analysis of the wrongness of killing by comparing different versions of three influential views: the traditional view that killing is always wrong; the liberal view that killing is wrong if and only if the victim does not want to be killed; and Don Marquis‟ future...... of value account of the wrongness of killing. In particular, I illustrate the advantages that a basic version of the liberal view and a basic version of the future of value account have over competing alternatives. Still, ultimately none of the views analysed here are satisfactory; but the different...... reasons why those competing views fail provide important insights into the ethics of killing....

  9. NASA GIBS Use in Live Planetarium Shows

    Science.gov (United States)

    Emmart, C. B.

    2015-12-01

    The American Museum of Natural History's Hayden Planetarium was rebuilt in year 2000 as an immersive theater for scientific data visualization to show the universe in context to our planet. Specific astrophysical movie productions provide the main daily programming, but interactive control software, developed at AMNH allows immersive presentation within a data aggregation of astronomical catalogs called the Digital Universe 3D Atlas. Since 2006, WMS globe browsing capabilities have been built into a software development collaboration with Sweden's Linkoping University (LiU). The resulting Uniview software, now a product of the company SCISS, is operated by about fifty planetariums around that world with ability to network amongst the sites for global presentations. Public presentation of NASA GIBS has allowed authoritative narratives to be presented within the range of data available in context to other sources such as Science on a Sphere, NASA Earth Observatory and Google Earth KML resources. Specifically, the NOAA supported World Views Network conducted a series of presentations across the US that focused on local ecological issues that could then be expanded in the course of presentation to national and global scales of examination. NASA support of for GIBS resources in an easy access multi scale streaming format like WMS has tremendously enabled particularly facile presentations of global monitoring like never before. Global networking of theaters for distributed presentations broadens out the potential for impact of this medium. Archiving and refinement of these presentations has already begun to inform new types of documentary productions that examine pertinent, global interdependency topics.

  10. The great American medicine show revisited.

    Science.gov (United States)

    Tomes, Nancy

    2005-01-01

    Since the late 1800s, changes in the advertising and marketing of medicinal drugs have produced heated debates in the United States. With the emergence of the modern prescription drug between 1938 and 1951, concerns that once focused primarily on patients' use of over-the-counter drugs were broadened to include physicians and their "doctors' drugs" as well. The medical profession's growing control over their patients' drug choices inevitably heightened the scrutiny of their own performance as consumers. Although deeply divided over issues of the patient's role in medical decision making, consumer activists and physician reformers expressed similar concerns about the impact of aggressive pharmaceutical marketing and advertising on the doctor-patient relationship, and starting in the late 1950s they employed strikingly similar strategies to counter the new corporate "medicine show." Yet their efforts to promote a more rational use of prescription drugs have usually been too little and too late to offset the effectiveness of pharmaceutical advertising and mar-keting activities.

  11. Tetrahydrobiopterin shows chaperone activity for tyrosine hydroxylase.

    Science.gov (United States)

    Thöny, Beat; Calvo, Ana C; Scherer, Tanja; Svebak, Randi M; Haavik, Jan; Blau, Nenad; Martinez, Aurora

    2008-07-01

    Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of catecholamine neurotransmitters. Primary inherited defects in TH have been associated with l-DOPA responsive and non-responsive dystonia and infantile parkinsonism. In this study, we show that both the cofactor (6R)-l-erythro-5,6,7,8-tetrahydrobiopterin (BH(4)) and the feedback inhibitor and catecholamine product dopamine increase the kinetic stability of human TH isoform 1 in vitro. Activity measurements and synthesis of the enzyme by in vitro transcription-translation revealed a complex regulation by the cofactor including both enzyme inactivation and conformational stabilization. Oral BH(4) supplementation to mice increased TH activity and protein levels in brain extracts, while the Th-mRNA level was not affected. All together our results indicate that the molecular mechanisms for the stabilization are a primary folding-aid effect of BH(4) and a secondary effect by increased synthesis and binding of catecholamine ligands. Our results also establish that orally administered BH(4) crosses the blood-brain barrier and therapeutic regimes based on BH(4) supplementation should thus consider the effect on TH. Furthermore, BH(4) supplementation arises as a putative therapeutic agent in the treatment of brain disorders associated with TH misfolding, such as for the human TH isoform 1 mutation L205P.

  12. The earliest published electrocardiogram showing ventricular preexcitation.

    Science.gov (United States)

    Von Knorre, Georg H

    2005-03-01

    When in 1930, Wolff, Parkinson, and White published what is today known as the WPW, or preexcitation syndrome, they, and subsequently others, found few comparable cases in the preceding literature. Among these the report of Cohn and Fraser, published in 1913, was the earliest. However, another even earlier documentation in a 1909 article by Hoffmann escaped notice till now. The ECG of a patient with paroxysmal tachycardia reveals a short PR interval and a delta-wave-induced widening of the QRS complex, even though the reproduced tachycardia was not preexcitation related. The interpretation of this poorly reproduced ECG can be confirmed by another and more detailed description of the patient in an electrocardiography textbook published in 1914 by the same author. Thus, the earliest publication of an ECG showing ventricular preexcitation now can be dated back to 1909. Moreover, the Hoffmann monograph contains two additional examples of the WPW syndrome not noticed until now. All three cases published by Hoffmann had their first ECG recordings in 1912 or earlier.

  13. Ribavirin shows immunomodulatory effects on activated microglia.

    Science.gov (United States)

    Savic, Danijela; Stojiljkovic, Mirjana; Lavrnja, Irena; Parabucki, Ana; Bjelobaba, Ivana; Nedeljkovic, Nadezda; Herdegen, Thomas; Pekovic, Sanja

    2014-12-01

    Abstract Ribavirin (RBV) is synthetic purine nucleoside analogue, licensed as anti-viral drug that displays immunomodulatory actions on various immune cells. Our previous ex vivo studies have demonstrated immunosuppressive effects of RBV on reactive T-lymphocytes in experimental autoimmune encephalomyelitis. Here, we examined the effects of RBV on inflammatory response of microglia. RBV potency to down-regulate microglia inflammatory response was assessed by measuring microglia cell body size, and the production of nitric oxide (NO) and pro- and anti-inflammatory cytokines. RBV exerted cytotoxic effects on LPS-stimulated microglia, leaving non-stimulated microglia unaffected. The exposure of activated microglia to RBV led to: decrease in the level of NO as a result of decreased cell number, lower average cell surface, the reduction of membrane ruffling, the suppression of interleukin-6 release and promoted interleukin-10 production. On the other hand, RBV promoted LPS-induced interleukin-1 beta release. Our results imply that RBV is a complex immunomodulator showing both anti- and pro-inflammatory effects on activated microglia.

  14. Preliminary studies of Pliocene speleothems from the Nullarbor Plain, southwest Australia

    Science.gov (United States)

    Sellman, Safana; Drysdale, Russell; Woodhead, Jon; Hellstrom, John

    2015-04-01

    The Pliocene (~2.58-5.33 Ma) is an important time interval for study of the Earth's climate system due to its potential as an analogue for future climates. However, there is a significant lack of terrestrial archives of palaeoclimate information for this period, and even fewer reliable estimates of palaeotemperature. There is also a distinct lack of data from Southern Hemisphere locations. This project is part of a larger study that aims to address these gaps by providing palaeohydrological and palaeotemperature reconstructions for the Pliocene using speleothems obtained from caves beneath the Nullarbor Plain, southern Australia. While to date, studies have largely focused on broad scale features for the entire Pliocene, this project will provide high-resolution records for specific time intervals (i.e. individual stalagmite growth periods) within this time frame. This research will provide a unique dataset of Pliocene climate that will have practical applications in informing the next generation of climate models future climate change. U-Pb dating of numerous Nullarbor speleothems shows that their growth spans from the late Miocene, through the Pliocene, and into the Pleistocene (Woodhead et al. in prep). A preliminary high-resolution study of two stalagmites (BT and M2) from Matilda Cave, both dated using the U-Pb method, will be presented. Stable isotope and fluid inclusion analyses were undertaken on both stalagmites. Modern rainfall samples from the region will be used to isotopically fingerprint dominant sources of modern precipitation, providing a basis on which to interpret conditions at the time of speleothem deposition. The presence of fluid inclusions suitable for analysis appears to be variable both spatially within the cave, and temporally. Thus sample BT provided water contents consistently too low for accurate fluid inclusion analyses, while sample M2 provided utilisable water contents during some growth periods but not in others. While the

  15. Preliminary safety design analysis of KALIMER

    Energy Technology Data Exchange (ETDEWEB)

    Suk, Soo Dong; Kwon, Y. M.; Kim, K. D. [Korea Atomic Energy Research Institute, Taejon (Korea)

    1999-03-01

    The national long-term R and D program updated in 1997 requires Korea Atomic Energy Research Institute(KAERI) to complete by the year 2006 the basic design of Korea Advanced Liquid Metal Reactor (KALIMER), along with supporting R and D work, with the capability of resolving the issue of spent fuel storage as well as with significantly enhanced safety. KALIMER is a 150 MWe pool-type sodium cooled prototype reactor that uses metallic fuel. The conceptual design is currently under way to establish a self consistent design meeting a set of the major safety design requirements for accident prevention. Some of current emphasis include those for inherent and passive means of negative reactivity insertion and decay heat removal, high shutdown reliability, prevention of and protection from sodium chemical reaction, and high seismic margin, among others. All of these requirements affect the reactor design significantly and involve supporting R and D programs of substance. This document first introduces a set of safety design requirements and accident evaluation criteria established for the conceptual design of KALIMER and then summarizes some of the preliminary results of engineering and design analyses performed for the safety of KALIMER. 19 refs., 19 figs., 6 tabs. (Author)

  16. Experimental Analyses for The Mechanical Behavior of Pressed All-Ceramic Molar Crowns with Anatomical Design

    Directory of Open Access Journals (Sweden)

    Porojan Liliana

    2017-01-01

    Full Text Available Ceramic restorations show considerable variation in strength and structural reliability regarding to the type of material, and design characteristics. The fracture of ceramics occurs with little or no plastic deformation, with cracks propagated in an unstable manner under applied tensile stresses. The aim of the study was to assess experimental analyses of pressed monolithic ceramic crowns with anatomical design used in the posterior areas in order to understand their mechanical behavior before following their clinical use. Experiments were conducted on a complete molar crown preparation. Experiments show different modes of fracture for the tested samples. Digital images from the fractured pieces of the crowns were used to verify the fragments in all cases final fracture occurred by splitting into two and often more parts. The graphically representation of the displacement depending on the load highlights a series of peaks that can be correlated with cracks occurred in crowns. The development of well-designed mechanical experiments could be useful to help to predict clinical survival of these new all-ceramic restorative techniques and materials. Because failure is often accompanied by complete cracking of the crowns, preliminary research should represents a compulsory goal.

  17. Preliminaries

    Directory of Open Access Journals (Sweden)

    Desde el jardín de Freud

    2014-10-01

    Full Text Available Desde el Jardín de Freud se encuentra indexada en el IBN-Publindex (Colciencias, en categoría C, y en Latindex. También se encuentra en las siguientes bases de datos y catálogos: ebsco, Dialnet, Rebiun, Doaj y e-Revistas.

  18. Pawnee Nation Energy Option Analyses

    Energy Technology Data Exchange (ETDEWEB)

    Matlock, M.; Kersey, K.; Riding In, C.

    2009-07-31

    In 2003, the Pawnee Nation leadership identified the need for the tribe to comprehensively address its energy issues. During a strategic energy planning workshop a general framework was laid out and the Pawnee Nation Energy Task Force was created to work toward further development of the tribe’s energy vision. The overarching goals of the “first steps” project were to identify the most appropriate focus for its strategic energy initiatives going forward, and to provide information necessary to take the next steps in pursuit of the “best fit” energy options. Based on the request of Pawnee Nation’s Energy Task Force the research team, consisting Tribal personnel and Summit Blue Consulting, focused on a review of renewable energy resource development potential, funding sources and utility organizational along with energy savings options. Elements of the energy demand forecasting and characterization and demand side options review remained in the scope of work, but were only addressed at a high level. Description of Activities Performed Renewable Energy Resource Development Potential The research team reviewed existing data pertaining to the availability of biomass (focusing on woody biomass, agricultural biomass/bio-energy crops, and methane capture), solar, wind and hydropower resources on the Pawnee-owned lands. Using these data, combined with assumptions about costs and revenue streams, the research team performed preliminary feasibility assessments for each resource category. The research team also reviewed available funding resources and made recommendations to Pawnee Nation highlighting those resources with the greatest potential for financially-viable development, both in the near-term and over a longer time horizon. Energy Efficiency Options While this was not a major focus of the project, the research team highlighted common strategies for reducing energy use in buildings. The team also discussed the benefits of adopting a building energy code and

  19. Analysing harmonic motions with an iPhone’s magnetometer

    Science.gov (United States)

    Yavuz, Ahmet; Kağan Temiz, Burak

    2016-05-01

    In this paper, we propose an experiment for analysing harmonic motion using an iPhone’s (or iPad’s) magnetometer. This experiment consists of the detection of magnetic field variations obtained from an iPhone’s magnetometer sensor. A graph of harmonic motion is directly displayed on the iPhone’s screen using the Sensor Kinetics application. Data from this application was analysed with Eureqa software to establish the equation of the harmonic motion. Analyses show that the use of an iPhone’s magnetometer to analyse harmonic motion is a practical and effective method for small oscillations and frequencies less than 15-20 Hz.

  20. MRI shows clodronate-liposomes attenuating liverinjuryinratswithsevereacutepancreatitis

    Institute of Scientific and Technical Information of China (English)

    Jian-Xin Zhang; Sheng-Chun Dang; Yong Zhang; Xin Sha; Li-Rong Zhang; Chuan-She Wei; Min Chen; De-Li Jiang

    2010-01-01

    BACKGROUND: Studies have revealed that macrophages play an important role in the development of severe acute pancreatitis (SAP). Activated macrophages can lead to a systemic inlfammatory response, induce lipid peroxidation, impair membrane structure, result in injury to the liver and the other extrahepatic organs, and eventually result in multiple organ dysfunction syndrome by promoting excessive secretion of cytokines. Liver injury can further aggravate the systemic inlfammatory response and increase mortality by affecting the metabolism of toxins and the release of excessive inlfammatory mediators. Clodronate is a synthetic bisphosphonate, which is often used for treating bone changes caused by osteoporosis and other factors. In the current study, we created liposomes containing superparamagnetic iron oxide particles (SPIOs) for macrophage labeling and magnetic resonance imaging, using a novel method that can bind the clodronate to induce apoptosis and deplete macrophages. METHODS: Superparamagnetic Fe3O4 nanoparticles were prepared by chemical coprecipitation. SPIO-containing liposomes and SPIO-clodronate-containing liposomes were prepared by the thin iflm method. SAP models were prepared by injection of sodium taurocholate (2 ml/kg body weight) into the subcapsular space of the pancreas. Sprague-Dawley rats were randomly divided into a control group, a SAP plus SPIO-liposome group, and a SAP plus SPIO-clodronate-containing group. Two and six hours after SAP models were available, T2-weighted MRI scans (in the same plane) of the livers of rats in each group were performed. At the end of the scans, 2 ml of blood was taken from the superior mesenteric vein to measure the levels of serum amylase, ALT, AST, TNF-α, and IL-6. Pathological changes in the liver and pancreas were assessed. RESULTS: Transmission electron microscopy showed that the liposomes had a uniform size. No pathological changes in the pancreata of rats in the control group were noted. The

  1. Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns

    Science.gov (United States)

    Sanchez-Mut, J V; Heyn, H; Vidal, E; Moran, S; Sayols, S; Delgado-Morales, R; Schultz, M D; Ansoleaga, B; Garcia-Esparcia, P; Pons-Espinal, M; de Lagran, M M; Dopazo, J; Rabano, A; Avila, J; Dierssen, M; Lott, I; Ferrer, I; Ecker, J R; Esteller, M

    2016-01-01

    Different neurodegenerative disorders often show similar lesions, such as the presence of amyloid plaques, TAU-neurotangles and synuclein inclusions. The genetically inherited forms are rare, so we wondered whether shared epigenetic aberrations, such as those affecting DNA methylation, might also exist. The studied samples were gray matter samples from the prefrontal cortex of control and neurodegenerative disease-associated cases. We performed the DNA methylation analyses of Alzheimer's disease, dementia with Lewy bodies, Parkinson's disease and Alzheimer-like neurodegenerative profile associated with Down's syndrome samples. The DNA methylation landscapes obtained show that neurodegenerative diseases share similar aberrant CpG methylation shifts targeting a defined gene set. Our findings suggest that neurodegenerative disorders might have similar pathogenetic mechanisms that subsequently evolve into different clinical entities. The identified aberrant DNA methylation changes can be used as biomarkers of the disorders and as potential new targets for the development of new therapies. PMID:26784972

  2. Preliminary data on Trachurus picturatus (Bowdich 1825 phylogeography inferred from mitochondrial DNA sequence data

    Directory of Open Access Journals (Sweden)

    Cláudia Filipa Moreira

    2015-11-01

    Full Text Available The populations of marine pelagic fishes, in particular the migratory ones as the Trachurus picturatus (Bowdich 1825, may be erroneously considered an homogenous population unit because they show broad geographic distributions, large population sizes and high migratory movements. The blue jack mackerel, T. picturatus is widely distributed in the NE Atlantic and also found in the Mediterranean and Black Seas. It is an economically important resource in the Macaronesian islands of Azores, Madeira and Canaries, but despite its fishery value and ecological importance, fluctuations in the landings are difficult to explain since studies regarding the population dynamics, stocks structure, fish movements and habitat connectivity are inexistent. Moreover, genetic methods that can act as a complementary tool for stock identification and population dynamics have never been applied to this species. The blue jack mackerel was sampled by artisanal fleets in the Islands of Azores, Madeira and Canaries, and at the Portuguese mainland - Matosinhos, Peniche and Portimão -during the spring-summer of 2013. A tissue sample was taken from each individual and stored in 96% ethanol for molecular analysis. Total DNA was successfully extracted, followed by a Polymerase Chain Reaction amplification of part of the cytochrome b gene (Cyt b. Amplifications and sequencing of the Cyt b gene were carried out using published primers used for the Carangidae family (Cárdenas et al. 2005. Sequences from Greece and Turkey, available on GenBank, were added to our sequences and all analysed together. In total 46 sequences were analysed, including the closely related outgroup (Trachurus Trachurus. Preliminary results show that there are sequences in the GenBank that are incorrectly assigned to this species. In addition, within the samples collected one was proven to be T. Trachurus. Preliminary phylogeographic analyses revealed a very shallow phylogenetic tree and a star

  3. Proteins analysed as virtual knots

    Science.gov (United States)

    Alexander, Keith; Taylor, Alexander J.; Dennis, Mark R.

    2017-02-01

    Long, flexible physical filaments are naturally tangled and knotted, from macroscopic string down to long-chain molecules. The existence of knotting in a filament naturally affects its configuration and properties, and may be very stable or disappear rapidly under manipulation and interaction. Knotting has been previously identified in protein backbone chains, for which these mechanical constraints are of fundamental importance to their molecular functionality, despite their being open curves in which the knots are not mathematically well defined; knotting can only be identified by closing the termini of the chain somehow. We introduce a new method for resolving knotting in open curves using virtual knots, which are a wider class of topological objects that do not require a classical closure and so naturally capture the topological ambiguity inherent in open curves. We describe the results of analysing proteins in the Protein Data Bank by this new scheme, recovering and extending previous knotting results, and identifying topological interest in some new cases. The statistics of virtual knots in protein chains are compared with those of open random walks and Hamiltonian subchains on cubic lattices, identifying a regime of open curves in which the virtual knotting description is likely to be important.

  4. Proteins analysed as virtual knots

    Science.gov (United States)

    Alexander, Keith; Taylor, Alexander J.; Dennis, Mark R.

    2017-01-01

    Long, flexible physical filaments are naturally tangled and knotted, from macroscopic string down to long-chain molecules. The existence of knotting in a filament naturally affects its configuration and properties, and may be very stable or disappear rapidly under manipulation and interaction. Knotting has been previously identified in protein backbone chains, for which these mechanical constraints are of fundamental importance to their molecular functionality, despite their being open curves in which the knots are not mathematically well defined; knotting can only be identified by closing the termini of the chain somehow. We introduce a new method for resolving knotting in open curves using virtual knots, which are a wider class of topological objects that do not require a classical closure and so naturally capture the topological ambiguity inherent in open curves. We describe the results of analysing proteins in the Protein Data Bank by this new scheme, recovering and extending previous knotting results, and identifying topological interest in some new cases. The statistics of virtual knots in protein chains are compared with those of open random walks and Hamiltonian subchains on cubic lattices, identifying a regime of open curves in which the virtual knotting description is likely to be important. PMID:28205562

  5. MagAl: A new tool to analyse galaxies photometric data

    Science.gov (United States)

    Schoenell, W.; Benítez, N.; Cid Fernandes, R.

    2014-10-01

    On galaxy spectra, one can find mainly two features: emission lines, which tell us about the ionised gas content, and the continuum plus absorption lines, which tell us about the stellar content. They thus allow us to derive gas-phase abundances, the main radiation sources, chemical enrichment and star formation histories. Braad-band photometry, on the other hand, is much more limited and hinders our ability to recover a galaxy's physical properties to such a degree of detail. However, with the recent development of redshift surveys using the technology of ultra-narrow filters (≍ 100 Å), such as ALHAMBRA, J-PAS and DES, it will be invaluable to be able to retrieve information on physical properties of galaxies from photometric data. Motivated by this data avalanche (which goes up to the petabyte scale), we decided to build our own SED-fitting code: Magnitudes Analyser (MagAl), which has three modules. 1) A template library generation module: generates empirical and theoretical template libraries. 2) Bayesian fitting module: calculates probability distribution functions (PDFs) for given observed and library template data. This is similar to the method to measure photometric redshifts by Benitez (2000). 3) A result-analyser module: streamlines data analysis from the large output PDFs files. A fourth module to manage 3D data is being developed and a few preliminary tests are also shown. To investigate the reliability of results obtained by MagAl, we have created a mock galaxy sample for the ALHAMBRA survey filter system (http://alhambrasurvey.com) and tried to recover their physical properties. We show that for our sample of simulated galaxies we can measure stellar ages, metallicities and extinctions with a precision of less than 0.3 dex. Also, we apply the code to the ALHAMBRA survey catalog and show that we can measure stellar masses with an accuracy of 0.2 dex when comparing to previous results like COSMOS masses measured by Bundy et al. (2006).

  6. Fractal and multifractal analyses of bipartite networks.

    Science.gov (United States)

    Liu, Jin-Long; Wang, Jian; Yu, Zu-Guo; Xie, Xian-Hua

    2017-03-31

    Bipartite networks have attracted considerable interest in various fields. Fractality and multifractality of unipartite (classical) networks have been studied in recent years, but there is no work to study these properties of bipartite networks. In this paper, we try to unfold the self-similarity structure of bipartite networks by performing the fractal and multifractal analyses for a variety of real-world bipartite network data sets and models. First, we find the fractality in some bipartite networks, including the CiteULike, Netflix, MovieLens (ml-20m), Delicious data sets and (u, v)-flower model. Meanwhile, we observe the shifted power-law or exponential behavior in other several networks. We then focus on the multifractal properties of bipartite networks. Our results indicate that the multifractality exists in those bipartite networks possessing fractality. To capture the inherent attribute of bipartite network with two types different nodes, we give the different weights for the nodes of different classes, and show the existence of multifractality in these node-weighted bipartite networks. In addition, for the data sets with ratings, we modify the two existing algorithms for fractal and multifractal analyses of edge-weighted unipartite networks to study the self-similarity of the corresponding edge-weighted bipartite networks. The results show that our modified algorithms are feasible and can effectively uncover the self-similarity structure of these edge-weighted bipartite networks and their corresponding node-weighted versions.

  7. Fractal and multifractal analyses of bipartite networks

    Science.gov (United States)

    Liu, Jin-Long; Wang, Jian; Yu, Zu-Guo; Xie, Xian-Hua

    2017-01-01

    Bipartite networks have attracted considerable interest in various fields. Fractality and multifractality of unipartite (classical) networks have been studied in recent years, but there is no work to study these properties of bipartite networks. In this paper, we try to unfold the self-similarity structure of bipartite networks by performing the fractal and multifractal analyses for a variety of real-world bipartite network data sets and models. First, we find the fractality in some bipartite networks, including the CiteULike, Netflix, MovieLens (ml-20m), Delicious data sets and (u, v)-flower model. Meanwhile, we observe the shifted power-law or exponential behavior in other several networks. We then focus on the multifractal properties of bipartite networks. Our results indicate that the multifractality exists in those bipartite networks possessing fractality. To capture the inherent attribute of bipartite network with two types different nodes, we give the different weights for the nodes of different classes, and show the existence of multifractality in these node-weighted bipartite networks. In addition, for the data sets with ratings, we modify the two existing algorithms for fractal and multifractal analyses of edge-weighted unipartite networks to study the self-similarity of the corresponding edge-weighted bipartite networks. The results show that our modified algorithms are feasible and can effectively uncover the self-similarity structure of these edge-weighted bipartite networks and their corresponding node-weighted versions. PMID:28361962

  8. Fractal and multifractal analyses of bipartite networks

    Science.gov (United States)

    Liu, Jin-Long; Wang, Jian; Yu, Zu-Guo; Xie, Xian-Hua

    2017-03-01

    Bipartite networks have attracted considerable interest in various fields. Fractality and multifractality of unipartite (classical) networks have been studied in recent years, but there is no work to study these properties of bipartite networks. In this paper, we try to unfold the self-similarity structure of bipartite networks by performing the fractal and multifractal analyses for a variety of real-world bipartite network data sets and models. First, we find the fractality in some bipartite networks, including the CiteULike, Netflix, MovieLens (ml-20m), Delicious data sets and (u, v)-flower model. Meanwhile, we observe the shifted power-law or exponential behavior in other several networks. We then focus on the multifractal properties of bipartite networks. Our results indicate that the multifractality exists in those bipartite networks possessing fractality. To capture the inherent attribute of bipartite network with two types different nodes, we give the different weights for the nodes of different classes, and show the existence of multifractality in these node-weighted bipartite networks. In addition, for the data sets with ratings, we modify the two existing algorithms for fractal and multifractal analyses of edge-weighted unipartite networks to study the self-similarity of the corresponding edge-weighted bipartite networks. The results show that our modified algorithms are feasible and can effectively uncover the self-similarity structure of these edge-weighted bipartite networks and their corresponding node-weighted versions.

  9. Topaz II preliminary safety assessment

    Science.gov (United States)

    Marshall, Albert C.; Standley, Vaughn; Voss, Susan S.; Haskin, Eric

    1993-01-01

    The Strategic Defense Initiative Organization (SDIO) decided to investigate the possibility of launching a Russian Topaz II space nuclear power system. A preliminary safety assessment was conducted to determine whether or not a space mission could be conducted safely and within budget constraints. As part of this assessment, a safety policy and safety functional requirements were developed to guide both the safety assessment and future Topaz II activities. A review of the Russian flight safety program was conducted and documented. Our preliminary safety assessment included a top level event tree, neutronic analysis of normal and accident configurations, an evaluation of temperature coefficients of reactivity, a reentry and disposal analysis, and analysis of postulated launch abort impact accidents, and an analysis of postulated propellant fire and explosion accidents. Based on the assessment, it appears that it will be possible to safely launch the Topaz II system in the U.S. with some possible system modifications. The principal system modifications will probably include design changes to preclude water flooded criticality and to assure intact reentry.

  10. Thermal Safety Analyses for the Production of Plutonium-238 at the High Flux Isotope Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Hurt, Christopher J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Freels, James D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Hobbs, Randy W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Jain, Prashant K. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Maldonado, G. Ivan [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-08-01

    There has been a considerable effort over the previous few years to demonstrate and optimize the production of plutonium-238 (238Pu) at the High Flux Isotope Reactor (HFIR). This effort has involved resources from multiple divisions and facilities at the Oak Ridge National Laboratory (ORNL) to demonstrate the fabrication, irradiation, and chemical processing of targets containing neptunium-237 (237Np) dioxide (NpO2)/aluminum (Al) cermet pellets. A critical preliminary step to irradiation at the HFIR is to demonstrate the safety of the target under irradiation via documented experiment safety analyses. The steady-state thermal safety analyses of the target are simulated in a finite element model with the COMSOL Multiphysics code that determines, among other crucial parameters, the limiting maximum temperature in the target. Safety analysis efforts for this model discussed in the present report include: (1) initial modeling of single and reduced-length pellet capsules in order to generate an experimental knowledge base that incorporate initial non-linear contact heat transfer and fission gas equations, (2) modeling efforts for prototypical designs of partially loaded and fully loaded targets using limited available knowledge of fabrication and irradiation characteristics, and (3) the most recent and comprehensive modeling effort of a fully coupled thermo-mechanical approach over the entire fully loaded target domain incorporating burn-up dependent irradiation behavior and measured target and pellet properties, hereafter referred to as the production model. These models are used to conservatively determine several important steady-state parameters including target stresses and temperatures, the limiting condition of which is the maximum temperature with respect to the melting point. The single pellet model results provide a basis for the safety of the irradiations, followed by parametric analyses in the initial prototypical designs

  11. Preliminary DNA fingerprinting of the turf grass Cynodon dactylon (Poaceae: Chloridoideae

    Directory of Open Access Journals (Sweden)

    R. Roodt

    2002-12-01

    Full Text Available Identification of different cultivars of turf grasses is often very difficult. In a preliminary attempt to identify different cultivars o f Cynodon dactylon (L. Pers.. random amplified polymorphic DNA (RAPD analyses of some well-known cultivars used in South Africa, i.e. Bayview. Cape Royal, Florida. Hamsmith. Silverton Blue. Skaapplaas and Titdwart. as well as 10 potential new cultivars, were done. These results were used to determine the genetic distances among cultivars. Only five primers w ere needed to obtain a specific fragment pattern for each cultivar. The degree o f amplification w as used as an additional criterion by including all visible fragments, excluding very faint fragments and only including the brightest fragments. The neighbour-joining trees o f C.  dactylon showed best resolution from the data set w ith all visible fragments included. although fragment intensity did not affect the tree topology. The cultivars Silverton Blue and Bayview exhibited the greatest genetic variation and two potential new cultivars were identified. RAPD analyses can. therefore, be used to distin­guish between different C. dactylon cultivars and to determine the genetic variation between them by calculating genetic distances.

  12. Preliminary DNA fingerprinting of the turf grass Cynodon dactylon (Poaceae: Chloridoideae

    Directory of Open Access Journals (Sweden)

    R. Roodt

    2002-12-01

    Full Text Available Identification of different cultivars of turf grasses is often very difficult. In a preliminary attempt to identify different cultivars o f Cynodon dactylon (L. Pers.. random amplified polymorphic DNA (RAPD analyses of some well-known cultivars used in South Africa, i.e. Bayview. Cape Royal, Florida. Hamsmith. Silverton Blue. Skaapplaas and Titdwart. as well as 10 potential new cultivars, were done. These results were used to determine the genetic distances among cultivars. Only five primers w ere needed to obtain a specific fragment pattern for each cultivar. The degree o f amplification w as used as an additional criterion by including all visible fragments, excluding very faint fragments and only including the brightest fragments. The neighbour-joining trees o f C.  dactylon showed best resolution from the data set w ith all visible fragments included. although fragment intensity did not affect the tree topology. The cultivars Silverton Blue and Bayview exhibited the greatest genetic variation and two potential new cultivars were identified. RAPD analyses can. therefore, be used to distin­guish between different C. dactylon cultivars and to determine the genetic variation between them by calculating genetic distances.

  13. ITER Safety Analyses with ISAS

    Science.gov (United States)

    Gulden, W.; Nisan, S.; Porfiri, M.-T.; Toumi, I.; de Gramont, T. Boubée

    1997-06-01

    Detailed analyses of accident sequences for the International Thermonuclear Experimental Reactor (ITER), from an initiating event to the environmental release of activity, have involved in the past the use of different types of computer codes in a sequential manner. Since these codes were developed at different time scales in different countries, there is no common computing structure to enable automatic data transfer from one code to the other, and no possibility exists to model or to quantify the effect of coupled physical phenomena. To solve this problem, the Integrated Safety Analysis System of codes (ISAS) is being developed, which allows users to integrate existing computer codes in a coherent manner. This approach is based on the utilization of a command language (GIBIANE) acting as a “glue” to integrate the various codes as modules of a common environment. The present version of ISAS allows comprehensive (coupled) calculations of a chain of codes such as ATHENA (thermal-hydraulic analysis of transients and accidents), INTRA (analysis of in-vessel chemical reactions, pressure built-up, and distribution of reaction products inside the vacuum vessel and adjacent rooms), and NAUA (transport of radiological species within buildings and to the environment). In the near future, the integration of S AFALY (simultaneous analysis of plasma dynamics and thermal behavior of in-vessel components) is also foreseen. The paper briefly describes the essential features of ISAS development and the associated software architecture. It gives first results of a typical ITER accident sequence, a loss of coolant accident (LOCA) in the divertor cooling loop inside the vacuum vessel, amply demonstrating ISAS capabilities.

  14. 23 CFR 645.109 - Preliminary engineering.

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Preliminary engineering. 645.109 Section 645.109 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS UTILITIES Utility Relocations, Adjustments, and Reimbursement § 645.109 Preliminary engineering. (a) As...

  15. 33 CFR 116.10 - Preliminary review.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Preliminary review. 116.10... ALTERATION OF UNREASONABLY OBSTRUCTIVE BRIDGES § 116.10 Preliminary review. (a) Upon receipt of a written complaint, the District Commander will review the complaint to determine if, in the District...

  16. Plutonium Immobilization Can Loading Preliminary Specifications

    Energy Technology Data Exchange (ETDEWEB)

    Kriikku, E.

    1998-11-25

    This report discusses the Plutonium Immobilization can loading preliminary equipment specifications and includes a process block diagram, process description, equipment list, preliminary equipment specifications, plan and elevation sketches, and some commercial catalogs. This report identifies loading pucks into cans and backfilling cans with helium as the top priority can loading development areas.

  17. 18 CFR 1b.6 - Preliminary investigations.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Preliminary investigations. 1b.6 Section 1b.6 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.6 Preliminary investigations....

  18. Preliminary evaluation of a self-report tool for Learned Helplessness and Mastery Orientation in Italian students.

    Directory of Open Access Journals (Sweden)

    Luana Sorrenti

    2014-12-01

    Full Text Available Learned helplessness (LH is defined as a passive behavior characterized by an inability to learn that may affect the academic success of students. Conversely, students who show good motivation skills, optimism and perseverance are more focused on tasks and ‘mastery oriented’ (derived from Mastery Orientation, MO. The purpose of this study was to develop a self-report measurement of LH and MO - the Learned Helplessness Questionnaire (LHQ - for the Italian scholastic context. We translated and adapted a student self-evaluation register, the Student behaviour checklist, and administered the questionnaire to Italian students in order to provide a preliminary factor structure. Exploratory factor analyses conducted support a two-factor model and acceptable internal reliability of the Italian LHQ.The results encourage the conduction of further analysis to assess the psychometric characteristics of the LHQ in depth.

  19. Development of an innovative microcantilever-based biosensor for 17β-estradiol detection in bovine muscles: preliminary results

    Directory of Open Access Journals (Sweden)

    Danilo Pitardi

    2013-06-01

    Full Text Available 17β-estradiol is the most powerful substance with estrogenic effect, commonly used as illegal growth promoter in livestock production. To avoid health risks for consumers, sensitive, reliable and low-cost methods for quantification of extremely low concentrations of such carcinogenic residues in food are needed. Antibody-immobilised microcantilever resonators were proposed as innovative biosensors able to quantify an adsorbed target mass thanks to a shift in resonance frequency. Furthermore, the quantification of masses on the order of few picograms has recently shown to be successfully achievable with very high precision. In this study, we analysed the performance of our microcantilever sensors using extracted samples of bovine muscle from experimental animals, containing variable concentrations of 17β-estradiol (HPLC-MS/MS tested. Preliminary data showed that treated animals are correctly revealed, exhibiting large negative frequency shifts. More experiments, though, are needed to obtain a correct quantification of 17β-estradiol concentration.

  20. Aging analyses of aircraft wire insulation

    Energy Technology Data Exchange (ETDEWEB)

    GILLEN,KENNETH T.; CLOUGH,ROGER LEE; CELINA,MATHIAS C.; AUBERT,JAMES H.; MALONE,G. MICHAEL

    2000-05-08

    Over the past two decades, Sandia has developed a variety of specialized analytical techniques for evaluating the long-term aging and stability of cable insulation and other related materials. These techniques have been applied to cable reliability studies involving numerous insulation types and environmental factors. This work has allowed the monitoring of the occurrence and progression of cable material deterioration in application environments, and has provided insights into material degradation mechanisms. It has also allowed development of more reliable lifetime prediction methodologies. As a part of the FAA program for intrusive inspection of aircraft wiring, they are beginning to apply a battery of techniques to assessing the condition of cable specimens removed from retired aircraft. It is anticipated that in a future part of this program, they may employ these techniques in conjunction with accelerated aging methodologies and models that the authros have developed and employed in the past to predict cable lifetimes. The types of materials to be assessed include 5 different wire types: polyimide, PVC/Glass/Nylon, extruded XL-polyalkene/PVDF, Poly-X, and XL-ETFE. This presentation provides a brief overview of the main techniques that will be employed in assessing the state of health of aircraft wire insulation. The discussion will be illustrated with data from their prior cable aging studies, highlighting the methods used and their important conclusions. A few of the techniques that they employ are widely used in aging studies on polymers, but others are unique to Sandia. All of their techniques are non-proprietary, and maybe of interest for use by others in terms of application to aircraft wiring analysis. At the end of this report is a list showing some leading references to papers that have been published in the open literature which provide more detailed information on the analytical techniques for elastomer aging studies. The first step in the

  1. Deproteinated palm kernel cake-derived oligosaccharides: A preliminary study

    Science.gov (United States)

    Fan, Suet Pin; Chia, Chin Hua; Fang, Zhen; Zakaria, Sarani; Chee, Kah Leong

    2014-09-01

    Preliminary study on microwave-assisted hydrolysis of deproteinated palm kernel cake (DPKC) to produce oligosaccharides using succinic acid was performed. Three important factors, i.e., temperature, acid concentration and reaction time, were selected to carry out the hydrolysis processes. Results showed that the highest yield of DPKC-derived oligosaccharides can be obtained at a parameter 170 °C, 0.2 N SA and 20 min of reaction time.

  2. KALIMER preliminary conceptual design report

    Energy Technology Data Exchange (ETDEWEB)

    Hahn, Do Hee; Kim, Y. J.; Kim, Y. G. and others

    2000-08-01

    This report, which summarizes the result of preliminary conceptual design activities during Phase 1, follows the format of safety analysis report. The purpose of publishing this report is to gather all of the design information developed so far in a systematic way so that KALIMER designers have a common source of the consistent design information necessary for their future design activities. This report will be revised and updated as design changes occur and more detailed design specification is developed during Phase 2. Chapter 1 describes the KALIMER Project. Chapter 2 includes the top level design requirements of KALIMER and general plant description. Chapter 3 summarizes the design of structures, components, equipment and systems. Specific systems and safety analysis results are described in the remaining chapters. Appendix on the HCDA evaluation is attached at the end of this report.

  3. Spatial and Alignment Analyses for a field of Small Volcanic Vents South of Pavonis Mons Mars

    Science.gov (United States)

    Bleacher, J. E.; Glaze, L. S.; Greeley, R.; Hauber, E.; Baloga, S. M.; Sakimoto, S. E. H.; Williams, D. A.; Glotch, T. D.

    2008-01-01

    The Tharsis province of Mars displays a variety of small volcanic vent (10s krn in diameter) morphologies. These features were identified in Mariner and Viking images [1-4], and Mars Orbiter Laser Altimeter (MOLA) data show them to be more abundant than originally observed [5,6]. Recent studies are classifying their diverse morphologies [7-9]. Building on this work, we are mapping the location of small volcanic vents (small-vents) in the Tharsis province using MOLA, Thermal Emission Imaging System, and High Resolution Stereo Camera data [10]. Here we report on a preliminary study of the spatial and alignment relationships between small-vents south of Pavonis Mons, as determined by nearest neighbor and two-point azimuth statistical analyses. Terrestrial monogenetic volcanic fields display four fundamental characteristics: 1) recurrence rates of eruptions,2 ) vent abundance, 3) vent distribution, and 4) tectonic relationships [11]. While understanding recurrence rates typically requires field measurements, insight into vent abundance, distribution, and tectonic relationships can be established by mapping of remotely sensed data, and subsequent application of spatial statistical studies [11,12], the goal of which is to link the distribution of vents to causal processes.

  4. Technical and economic analyses of hydrogen production via indirectly heated gasification and pyrolysis

    Energy Technology Data Exchange (ETDEWEB)

    Mann, M.K. [National Renewable Energy Laboratory, Golden, CO (United States)

    1995-09-01

    Technoeconomic analyses have been conducted on two processes to produce hydrogen from biomass: indirectly-heated gasification of biomass followed by steam reforming of the syngas, and biomass pyrolysis followed by steam reforming of the pyrolysis oil. The analysis of the gasification-based process was highly detailed, including a process flowsheet, material and energy balances calculated with a process simulation program, equipment cost estimation, and the determination of the necessary selling price of hydrogen. The pyrolysis-based process analysis was of a less detailed nature, as all necessary experimental data have not been obtained; this analysis is a follow-up to the preliminary economic analysis presented at the 1994 Hydrogen Program Review. A coproduct option in which pyrolysis oil is used to produce hydrogen and a commercial adhesive was also studied for economic viability. Based on feedstock availability estimates, three plant sizes were studied: 907 T/day, 272 T/day, and 27 T/day. The necessary selling price of hydrogen produced by steam reforming syngas from the Battelle Columbus Laboratories indirectly heated biomass gasifier falls within current market values for the large and medium size plants within a wide range of feedstock costs. Results show that the small scale plant does not produce hydrogen at economically competitive prices, indicating that if gasification is used as the upstream process to produce hydrogen, local refueling stations similar to current gasoline stations, would probably not be feasible.

  5. Analysing degeneracies in networks spectra

    CERN Document Server

    Marrec, Loïc

    2016-01-01

    Many real-world networks exhibit a high degeneracy at few eigenvalues. We show that a simple transformation of the network's adjacency matrix provides an understanding of? the origins of occurrence of high multiplicities in the networks spectra. We find that the eigenvectors associated with the degenerate eigenvalues shed light on the structures contributing to the degeneracy. Since these degeneracies are rarely observed in model graphs, we present results for various cancer networks. This approach gives an opportunity to search for structures contributing to degeneracy which might have an important role in a network.

  6. Meditation effects on cognitive function and cerebral blood flow in subjects with memory loss: a preliminary study.

    Science.gov (United States)

    Newberg, Andrew B; Wintering, Nancy; Khalsa, Dharma S; Roggenkamp, Hannah; Waldman, Mark R

    2010-01-01

    This preliminary study determined if subjects with memory loss problems demonstrate changes in memory and cerebral blood flow (CBF) after a simple 8-week meditation program. Fourteen subjects with memory problems had an IV inserted and were injected with 250 MBq of Tc-99m ECD while listening to a neutral stimulus CD. They then underwent a pre-program baseline SPECT scan. Then subjects were guided through their first meditation session with a CD, during which they received an injection of 925 MBq ECD, and underwent a pre-program meditation scan. Subjects completed an 8-week meditation program and underwent the same scanning protocol resulting in a post-program baseline and meditation scan. A region of interest (ROI) template obtained counts in each ROI normalized to whole brain to provide a CBF ratio. Baseline and meditation scans and neuropsychological testing were compared before and after the program. The meditation program resulted in significant increases (pmemory showed improvements after training. This preliminary study evaluated whether an 8-week meditation program resulted in improvements in neuropsychological function and differences in CBF in subjects with memory loss. While the findings are encouraging, there are a number of limitations that can be addressed in future studies with more participants and more detailed analyses.

  7. Five Kepler target stars that show multiple transiting exoplanet candidates

    Energy Technology Data Exchange (ETDEWEB)

    Steffen, Jason H.; /Fermilab; Batalha, Natalie M.; /San Jose State U.; Borucki, William J.; /NASA, Ames; Buchhave, Lars A.; /Harvard-Smithsonian Ctr. Astrophys. /Bohr Inst.; Caldwell, Douglas A.; /NASA, Ames /SETI Inst., Mtn. View; Cochran, William D.; /Texas U.; Endl, Michael; /Texas U.; Fabrycky, Daniel C.; /Harvard-Smithsonian Ctr. Astrophys.; Fressin, Francois; /Harvard-Smithsonian Ctr. Astrophys.; Ford, Eric B.; /Florida U.; Fortney, Jonathan J.; /UC, Santa Cruz, Phys. Dept. /NASA, Ames

    2010-06-01

    We present and discuss five candidate exoplanetary systems identified with the Kepler spacecraft. These five systems show transits from multiple exoplanet candidates. Should these objects prove to be planetary in nature, then these five systems open new opportunities for the field of exoplanets and provide new insights into the formation and dynamical evolution of planetary systems. We discuss the methods used to identify multiple transiting objects from the Kepler photometry as well as the false-positive rejection methods that have been applied to these data. One system shows transits from three distinct objects while the remaining four systems show transits from two objects. Three systems have planet candidates that are near mean motion commensurabilities - two near 2:1 and one just outside 5:2. We discuss the implications that multitransiting systems have on the distribution of orbital inclinations in planetary systems, and hence their dynamical histories; as well as their likely masses and chemical compositions. A Monte Carlo study indicates that, with additional data, most of these systems should exhibit detectable transit timing variations (TTV) due to gravitational interactions - though none are apparent in these data. We also discuss new challenges that arise in TTV analyses due to the presence of more than two planets in a system.

  8. Five Kepler Target Stars That Show Multiple Transiting Exoplanet Candidates

    Science.gov (United States)

    Steffen, Jason H.; Batalha, Natalie M.; Borucki, William J.; Buchhave, Lars A.; Caldwell, Douglas A.; Cochran, William D.; Endl, Michael; Fabrycky, Daniel C.; Fressin, François; Ford, Eric B.; Fortney, Jonathan J.; Haas, Michael J.; Holman, Matthew J.; Howell, Steve B.; Isaacson, Howard; Jenkins, Jon M.; Koch, David; Latham, David W.; Lissauer, Jack J.; Moorhead, Althea V.; Morehead, Robert C.; Marcy, Geoffrey; MacQueen, Phillip J.; Quinn, Samuel N.; Ragozzine, Darin; Rowe, Jason F.; Sasselov, Dimitar D.; Seager, Sara; Torres, Guillermo; Welsh, William F.

    2010-12-01

    We present and discuss five candidate exoplanetary systems identified with the Kepler spacecraft. These five systems show transits from multiple exoplanet candidates. Should these objects prove to be planetary in nature, then these five systems open new opportunities for the field of exoplanets and provide new insights into the formation and dynamical evolution of planetary systems. We discuss the methods used to identify multiple transiting objects from the Kepler photometry as well as the false-positive rejection methods that have been applied to these data. One system shows transits from three distinct objects while the remaining four systems show transits from two objects. Three systems have planet candidates that are near mean motion commensurabilities—two near 2:1 and one just outside 5:2. We discuss the implications that multi-transiting systems have on the distribution of orbital inclinations in planetary systems, and hence their dynamical histories, as well as their likely masses and chemical compositions. A Monte Carlo study indicates that, with additional data, most of these systems should exhibit detectable transit timing variations (TTVs) due to gravitational interactions, though none are apparent in these data. We also discuss new challenges that arise in TTV analyses due to the presence of more than two planets in a system.

  9. Astor Pass Seismic Surveys Preliminary Report

    Energy Technology Data Exchange (ETDEWEB)

    Louie, John [UNR; Pullammanappallil, Satish [Optim; Faulds, James; Eisses, Amy; Kell, Annie; Frary, Roxanna; Kent, Graham

    2011-08-05

    In collaboration with the Pyramid Lake Paiute Tribe (PLPT), the University of Nevada, Reno (UNR) and Optim re-processed, or collected and processed, over 24 miles of 2d seismic-reflection data near the northwest corner of Pyramid Lake, Nevada. The network of 2d land surveys achieved a near-3d density at the Astor Pass geothermal prospect that the PLPT drilled during Nov. 2010 to Feb. 2011. The Bureau of Indian Affairs funded additional seismic work around the Lake, and an extensive, detailed single-channel marine survey producing more than 300 miles of section, imaging more than 120 ft below the Lake bottom. Optim’s land data collection utilized multiple heavy vibrators and recorded over 200 channels live, providing a state-of-the-art reflection-refraction data set. After advanced seismic analysis including first-arrival velocity optimization and prestack depth migration, the 2d sections show clear fault-plane reflections, in some areas as deep as 4000 ft, tying to distinct terminations of the mostly volcanic stratigraphy. Some lines achieved velocity control to 3000 ft depth; all lines show reflections and terminations to 5000 ft depth. Three separate sets of normal faults appear in an initial interpretation of fault reflections and stratigraphic terminations, after loading the data into the OpendTect 3d seismic visualization system. Each preliminary fault set includes a continuous trace more than 3000 ft long, and a swarm of short fault strands. The three preliminary normal-fault sets strike northerly with westward dip, northwesterly with northeast dip, and easterly with north dip. An intersection of all three fault systems documented in the seismic sections at the end of Phase I helped to locate the APS-2 and APS-3 slimholes. The seismic sections do not show the faults connected to the Astor Pass tufa spire, suggesting that we have imaged mostly Tertiary-aged faults. We hypothesize that the Recent, active faults that produced the tufa through hotspring

  10. Sensitivity Study of Poisson's Ratio Used in Soil Structure Interaction (SSI) Analyses

    Energy Technology Data Exchange (ETDEWEB)

    Han, Seung-ju [KHNP CRI, Daejeon (Korea, Republic of); You, Dong-Hyun [KEPCO Engineering and Construction, Gimcheon (Korea, Republic of); Jang, Jung-bum; Yun, Kwan-hee [KEPCO Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    The preliminary review for Design Certification (DC) of APR1400 was accepted by NRC on March 4, 2015. After the acceptance of the application for standard DC of APR1400, KHNP has responded the Request for Additional Information (RAI) raised by NRC to undertake a full design certification review. Design certification is achieved through the NRC's rulemaking process, and is founded on the staff's review of the application, which addresses the various safety issues associated with the proposed nuclear power plant design, independent of a specific site. The USNRC issued RAIs pertain to Design Control Document (DCD) Ch.3.7 'Seismic Design' is DCD Tables 3.7A-1 and 3.7A-2 show Poisson’s ratios in the S1 and S2 soil profiles used for SSI analysis as great as 0.47 and 0.48 respectively. Based on staff experience, use of Poisson's ratio approaching these values may result in numerical instability of the SSI analysis results. Sensitivity study is performed using the ACS SASSI NI model of APR1400 with S1 and S2 soil profiles to demonstrate that the Poisson’s ratio values used in the SSI analyses of S1 and S2 soil profile cases do not produce numerical instabilities in the SSI analysis results. No abrupt changes or spurious peaks, which tend to indicate existence of numerical sensitivities in the SASSI solutions, appear in the computed transfer functions of the original SSI analyses that have the maximum dynamic Poisson’s ratio values of 0.47 and 0.48 as well as in the re-computed transfer functions that have the maximum dynamic Poisson’s ratio values limited to 0.42 and 0.45.

  11. Feasibility Analyses of Integrated Broiler Production

    Directory of Open Access Journals (Sweden)

    L. Komalasari

    2010-12-01

    Full Text Available The major obstacles in the development of broiler raising is the expensive price of feed and the fluctuative price of DOCs. The cheap price of imported leg quarters reduces the competitiveness of the local broilers. Therefore, an effort to increase production efficiency is needed through integration between broiler raising and corn farmers and feed producers (integrated farming. The purpose of this study is to analyze the feasibility of integrating broiler raising with corn cultivation and feed production. Besides that, a simulation was conducted to analyze the effects of DOC price changes, broiler price and production capacity. The analyses showed that integrated farming and a mere combination between broiler raising and feed factory of a 10,000 bird capacity is not financially feasible. Increasing the production to 25,000 broiler chickens will make the integrated farming financially feasible. Unintegrated broiler raising is relatively sensitive to broiler price decreases and DOC price increases compared to integrated farming.

  12. Analysing Medieval Urban Space; a methodology

    Directory of Open Access Journals (Sweden)

    Marlous L. Craane MA

    2007-08-01

    Full Text Available This article has been written in reaction to recent developments in medieval history and archaeology, to study not only the buildings in a town but also the spaces that hold them together. It discusses a more objective and interdisciplinary approach for analysing urban morphology and use of space. It proposes a 'new' methodology by combining town plan analysis and space syntax. This methodology was trialled on the city of Utrecht in the Netherlands. By comparing the results of this 'new' methodology with the results of previous, more conventional, research, this article shows that space syntax can be applied successfully to medieval urban contexts. It does this by demonstrating a strong correlation between medieval economic spaces and the most integrated spaces, just as is found in the study of modern urban environments. It thus provides a strong basis for the use of this technique in future research of medieval urban environments.

  13. Analysing Terrorism from a Systems Thinking Perspective

    Directory of Open Access Journals (Sweden)

    Lukas Schoenenberger

    2014-02-01

    Full Text Available Given the complexity of terrorism, solutions based on single factors are destined to fail. Systems thinking offers various tools for helping researchers and policy makers comprehend terrorism in its entirety. We have developed a semi-quantitative systems thinking approach for characterising relationships between variables critical to terrorism and their impact on the system as a whole. For a better understanding of the mechanisms underlying terrorism, we present a 16-variable model characterising the critical components of terrorism and perform a series of highly focused analyses. We show how to determine which variables are best suited for government intervention, describing in detail their effects on the key variable—the political influence of a terrorist network. We also offer insights into how to elicit variables that destabilise and ultimately break down these networks. Because we clarify our novel approach with fictional data, the primary importance of this paper lies in the new framework for reasoning that it provides.

  14. First international intercomparison of image analysers

    CERN Document Server

    Pálfalvi, J; Eoerdoegh, I

    1999-01-01

    Image analyser systems used for evaluating solid state nuclear track detectors (SSNTD) were compared in order to establish minimum hardware and software requirements and methodology necessary in different fields of radiation dosimetry. For the purpose, CR-39 detectors (TASL, Bristol, U.K.) were irradiated with different (n,alpha) and (n,p) converters in a reference Pu-Be neutron field, in an underground laboratory with high radon concentration and by different alpha sources at the Atomic Energy Research Institute (AERI) in Budapest, Hungary. 6 sets of etched and pre-evaluated detectors and the 7th one without etching were distributed among the 14 laboratories from 11 countries. The participants measured the different track parameters and statistically evaluated the results, to determine the performance of their system. The statistical analysis of results showed high deviations from the mean values in many cases. As the conclusion of the intercomparison recommendations were given to fulfill those requirements ...

  15. Preliminary results of radiation monitoring near uranium mines in Namibia EJOLT Project (DRAFT version)

    Energy Technology Data Exchange (ETDEWEB)

    Chareyron, Bruno

    2012-04-05

    As a part of the EJOLT (Environmental Justice Organizations Liability and Trade) project, EARTHLIFE Namibia and CRIIRAD (Commission for Independent Research and Information about Radiation) have organised visits in areas located in the vicinity of uranium mines in Namibia In the course of an on site mission carried out between September 22 and October 2 2011, scientists from the CRIIRAD laboratory took radiation measurements in situ, and collected 14 samples of top soil, 13 samples of surface sediments of the Swakop, Gawib and Khan rivers, 11 underground water samples in the alluvium of Swakop, and Khan rivers and tap water from Arandis city, and one sample of asparagus. Solid samples have been analysed at the CRIIRAD laboratory in France (measurements performed by HpGe gamma spectrometry) and water samples have been monitored for main chemicals by LDA 26 laboratory in France and for radium 226 and radon 222 at the CRIIRAD laboratory. Some of the preliminary findings are summarised in this report: 1 - The dose rate measured by CRIIRAD on the parking of Roessing mine is about 6 times above natural background value (0.9 {mu}Sv/h compared to 0.15 {mu}Sv/h); 2 - The management of waste rock dumps needs to be improved: Some waste rocks are dumped on the banks of Khan river (at the intersection with Dome Gorge) without fencing and confinement. The radiological impact of this activity has to be studied in detail but preliminary measurements show various impacts on the environment; 3 - The finest fraction of the radioactive tailings dumped on Roessing tailings dam is blown away by the wind and contaminates the surrounding environment; 4 - The high uranium concentration in underground water collected downstream Roessing uranium mine in the Khan river and Swakop river alluvium raises the question of the origin of this uranium

  16. BASE Flexible Array Preliminary Lithospheric Structure Analysis

    Science.gov (United States)

    Yeck, W. L.; Sheehan, A. F.; Anderson, M. L.; Siddoway, C. S.; Erslev, E.; Harder, S. H.; Miller, K. C.

    2009-12-01

    The Bighorns Arch Seismic Experiment (BASE) is a Flexible Array experiment integrated with EarthScope. The goal of BASE is to develop a better understanding of how basement-involved foreland arches form and what their link is to plate tectonic processes. To achieve this goal, the crustal structure under the Bighorn Mountain range, Bighorn Basin, and Powder River Basin of northern Wyoming and southern Montana are investigated through the deployment of 35 broadband seismometers, 200 short period seismometers, 1600 “Texan” instruments using active sources and 800 “Texan” instruments monitoring passive sources, together with field structural analysis of brittle structures. The novel combination of these approaches and anticipated simultaneous data inversion will give a detailed structural crustal image of the Bighorn region at all levels of the crust. Four models have been proposed for the formation of the Bighorn foreland arch: subhorizontal detachment within the crust, lithospheric buckling, pure shear lithospheric thickening, and fault blocks defined by lithosphere-penetrating thrust faults. During the summer of 2009, we deployed 35 broadband instruments, which have already recorded several magnitude 7+ teleseismic events. Through P wave receiver function analysis of these 35 stations folded in with many EarthScope Transportable Array stations in the region, we present a preliminary map of the Mohorovicic discontinuity. This crustal map is our first test of how the unique Moho geometries predicted by the four hypothesized models of basement involved arches fit seismic observations for the Bighorn Mountains. In addition, shear-wave splitting analysis for our first few recorded teleseisms helps us determine if strong lithospheric deformation is preserved under the range. These analyses help lead us to our final goal, a complete 4D (3D spatial plus temporal) lithospheric-scale model of arch formation which will advance our understanding of the mechanisms

  17. Show Horse Welfare: Horse Show Competitors' Understanding, Awareness, and Perceptions of Equine Welfare.

    Science.gov (United States)

    Voigt, Melissa A; Hiney, Kristina; Richardson, Jennifer C; Waite, Karen; Borron, Abigail; Brady, Colleen M

    2016-01-01

    The purpose of this study was to gain a better understanding of stock-type horse show competitors' understanding of welfare and level of concern for stock-type show horses' welfare. Data were collected through an online questionnaire that included questions relating to (a) interest and general understanding of horse welfare, (b) welfare concerns of the horse show industry and specifically the stock-type horse show industry, (c) decision-making influences, and (d) level of empathic characteristics. The majority of respondents indicated they agree or strongly agree that physical metrics should be a factor when assessing horse welfare, while fewer agreed that behavioral and mental metrics should be a factor. Respondent empathy levels were moderate to high and were positively correlated with the belief that mental and behavioral metrics should be a factor in assessing horse welfare. Respondents indicated the inhumane practices that most often occur at stock-type shows include excessive jerking on reins, excessive spurring, and induced excessive unnatural movement. Additionally, respondents indicated association rules, hired trainers, and hired riding instructors are the most influential regarding the decisions they make related to their horses' care and treatment.

  18. Topological Analyses of Symmetric Eruptive Prominences

    Science.gov (United States)

    Panasenco, O.; Martin, S. F.

    Erupting prominences (filaments) that we have analyzed from Hα Doppler data at Helio Research and from SOHO/EIT 304 Å, show strong coherency between their chirality, the direction of the vertical and lateral motions of the top of the prominences, and the directions of twisting of their legs. These coherent properties in erupting prominences occur in two patterns of opposite helicity; they constitute a form of dynamic chirality called the ``roll effect." Viewed from the positive network side as they erupt, many symmetrically-erupting dextral prominences develop rolling motion toward the observer along with right-hand helicity in the left leg and left-hand helicity in the right leg. Many symmetricaly-erupting sinistral prominences, also viewed from the positive network field side, have the opposite pattern: rolling motion at the top away from the observer, left-hand helical twist in the left leg, and right-hand twist in the right leg. We have analysed the motions seen in the famous movie of the ``Grand Daddy" erupting prominence and found that it has all the motions that define the roll effect. From our analyses of this and other symmetric erupting prominences, we show that the roll effect is an alternative to the popular hypothetical configuration of an eruptive prominence as a twisted flux rope or flux tube. Instead we find that a simple flat ribbon can be bent such that it reproduces nearly all of the observed forms. The flat ribbon is the most logical beginning topology because observed prominence spines already have this topology prior to eruption and an initial long magnetic ribbon with parallel, non-twisted threads, as a basic form, can be bent into many more and different geometrical forms than a flux rope.

  19. Preliminary pharmacognostic screening of Achyranthes coynei stem

    Directory of Open Access Journals (Sweden)

    Vinayak Upadhya

    2015-01-01

    Full Text Available Achyranthes coynei is a rare, endemic perennial shrub reported from Karnataka and Maharashtra states of India. The plant is used to treat various disorders by folk healers and was proven to have antimicrobial and antioxidant properties. The present study was undertaken to evaluate microscopic and macroscopic characters of A. coynei stem, along with its physicochemical parameters. ProgRes ® CapturePro and Microsoft Excel were used for statistical analysis. Perennial, shrubby nature and woody stem were the distinguishing morphological characters observed. Transverse section (TS illustrated quadrangular outline of the stem and showed the presence of two types of trichomes on the thick-walled epidermis. TS also showed number of rosette calcium oxalates crystals; prismatic and microsphenoid crystals; conjoint, collateral open secondary vascular bundles; and two amphixylic medullary bundles in the pith. Ash and extractive values, micro and macro elements and nutritive factors were estimated in the present study. The presence of alkaloids, saponins and triterpenoids were observed in preliminary phytochemical screening. High-performance thin layer chromatographic analysis yielded different bands and also indicated the presence of oleanolic acid. The studied parameters for A. coynei stem will be useful for identification and authentication of the plant material.

  20. Techniques for Analysing Problems in Engineering Projects

    DEFF Research Database (Denmark)

    Thorsteinsson, Uffe

    1998-01-01

    Description of how CPM network can be used for analysing complex problems in engineering projects.......Description of how CPM network can be used for analysing complex problems in engineering projects....

  1. Techniques for Analysing Problems in Engineering Projects

    DEFF Research Database (Denmark)

    Thorsteinsson, Uffe

    1998-01-01

    Description of how CPM network can be used for analysing complex problems in engineering projects.......Description of how CPM network can be used for analysing complex problems in engineering projects....

  2. MSL SAM-like Analyses of Hawaiian Altered Basaltic Materials: Implications for Analyses by the Mars Science Laboratory

    Science.gov (United States)

    McAdam, A.; Eigenbrode, J. L.; Young, K. E.; Bleacher, J. E.; Knudson, C. A.; Rogers, D.; Glotch, T. D.; Sutter, B.; Mahaffy, P. R.; Navarro-Gonzalez, R.; Downs, R. T.

    2015-12-01

    Samples of basaltic materials were collected during several traverses of the Kau Desert on the leeward side of the Kilauea Volcano, Hawaii, conducted by the Remote, In Situ, and Synchrotron Studies for Science and Exploration (RIS4E) team, a node of the Solar System Exploration and Research Virtual Institute (SSERVI) program. Some of these samples had been exposed to circumneutral to slightly acidic alteration conditions from exposure to fog/rain, and acidic fog/rain, while others had been exposed to more acidic conditions due to proximity to fumaroles. The samples consisted of basalts with coatings, sands and soils, and ash, and were collected using organically clean protocols to enable investigation of organic chemistry and organic-mineral associations, in addition to mineralogy. The Mars Science Laboratory (MSL) rover has analyzed basaltic materials inferred to have been altered under conditions ranging from circumneutral to acidic, but several aspects of the Sample Analysis at Mars (SAM) instrument suite results are still being investigated and analyses of relevant terrestrial analogs can play an important role in interpretation of the data. For example, all materials analyzed to date have a significant amorphous component. Comparisons of the mineralogy obtained with the MSL CheMin instrument and volatiles evolved during SAM analyses indicate that, by mass balance, some portion of the volatiles, such as SO2 and H2O, are likely associated with this component. Many of the RIS4E samples also have a significant amorphous component, and field x-ray diffraction (XRD) and x-ray fluorescence (XRF) data indicate differences in the chemistry of this material in samples exposed to different alteration conditions. Preliminary SAM-like analyses indicate that the amorphous materials in some of these samples evolve volatiles such as H2O and SO2 during heating. Here we will discuss these results, and others, obtained through SAM-like analyses of selected samples.

  3. Preliminary Hydrogeochemical Site Description SFR (version 0.2)

    Energy Technology Data Exchange (ETDEWEB)

    Nilsson, Ann-Chatrin (Geosigma AB, Uppaala (Sweden)); Tullborg, Eva-Lena (Terralogica AB, Graabo (Sweden)); Smellie, John (Conterra AB, Partille (Sweden))

    2010-05-15

    The final repository for low and intermediate level radioactive operational waste, SFR, located about 150 km north of Stockholm, is to undergo a future extension. The present on-going project, scheduled from 2007 to 2011, is to define and characterise a suitable bedrock volume for the extended repository. This will include the drilling and geoscientific evaluation of seven core-drilled and four percussion boreholes as well as subsequent interpretation and modelling based on the obtained results in order to provide the necessary information for safety assessment and repository design. This report presents a preliminary hydrogeochemical site description for the SFR site and should be considered as an early progress report rather than a complete hydrochemical site descriptive model. The completed hydrogeochemical field investigations have yielded chemical data from a total of 12 borehole sections in five boreholes and additional data from the entire length of two open boreholes in connection with hydraulic tests. These data, together with data from a total of 18 early boreholes in the present SFR tunnel system, were used in the interpretation work. The main part of the data consisted of basic groundwater analyses including major ions and isotopes. Some sporadic gas, microbe and measured redox data are available, but these are either not treated in this report, or are only briefly discussed. This was due to time constraints since special care is needed when interpreting few data of varying quality. The groundwaters in the SFR dataset cover a maximum depth down to about .400 masl and represent a relatively limited salinity range (1,500 to 5,500 mg/L chloride). However, the delta18O values show a wide variation (-1.55 to -0.75% V-SMOW) similar to that reported from the Forsmark site investigations. At the SFR, marine indicators such as Mg/Cl, K/Cl and Br/Cl also show relatively large variations considering the limited salinity range. From very few measured Eh values, and

  4. A secondary X-ray analyser using a flat ring-shaped radially graded multilayer

    CERN Document Server

    Buzykaeva, A N; Kovalenko, N V; Mytnichenko, S V

    2001-01-01

    A new type of efficient energy analyser specialised for thin film studies is suggested. The key feature of the analyser is the use of a ring-shaped, flat multilayer with d-spacing linearly increasing with radius. At small angles of diffraction, a gradual extension of multilayer period ensures isochromatic Bragg reflection of divergent X-rays emitted by the sample. The main advantages of this kind of secondary analyser are as follows: (1) a rather large acceptance angle (0.1-0.3 sr); (2) good energy resolution (2-3%) and (3) easy tuning in a wide energy range. The instrument is particularly suited for grazing-exit fluorescence X-ray absorption fine structure (XAFS) and XMCD studies with spatial resolution. A prototype graded W/Si multilayer with a change of period of about 30% was fabricated and tested. Preliminary results taken with the K fluorescence emission of copper film are presented to demonstrate feasibility of the analyser.

  5. Functional MRI evidence for language plasticity in adult epileptic patients: Preliminary results

    Directory of Open Access Journals (Sweden)

    Emilie Cousin

    2008-03-01

    Full Text Available Emilie Cousin1, Monica Baciu1, Cédric Pichat1, Philippe Kahane2, Jean-François Le Bas31UMR CNRS/UPMF 5105, Laboratoire de Psychologie et Neurocognition; 2Laboratoire de Neurophysiopathologie de l’Epilepsie, CHU Grenoble; 3Unité IRM, CHU Grenoble, FranceAbstract: The present fMRI study explores the cerebral reorganisation of language in patients with temporal lobe epilepsy, according to the age of seizures onset (early or late and the hippocampal sclerosis (associated or not. Seven right-handed control volunteers and seven preoperative adult epileptic patients performed a rhyme decision (language condition and a visual detection (control condition tasks in visually presented words and unreadable characters, respectively. All patients were left hemisphere dominant for language. Appropriate statistical analyses provided the following preliminary results: (1 patients compared with healthy subjects showed lower degree of hemispheric lateralization with supplementary involvement of the right hemisphere; (2 the degree of hemispheric specialization depends on the considered region; (3 patients with early seizures show signs of temporal and parietal reorganization more frequently than patients with late onset of seizures; (4 patients with early seizures show a tendency for intra-hemispheric frontal reorganisation; (5 associated hippocampal sclerosis facilitates the inter-hemispheric shift of temporal activation. Although our patients were left hemisphere predominant for language, the statistical analyses indicated that the degree of lateralization was significantly lower than in healthy subjects. This result has been considered as the indication of atypical lateralization of language.Keywords: language, fMRI, plasticity, temporal epilepsy, age, hippocampal sclerosis

  6. Preliminary Geochemical and Rock Magnetic Study of a Stalagmite From Quintana Roo, Northeastern Yucatan Peninsula

    Science.gov (United States)

    Urrutia-Fucugauchi, J.; Perez-Cruz, L.; Zhao, X.; Rebolledo-Vieyra, M.; Rodriguez, A.

    2012-04-01

    We present the preliminary results of geochemical, stable isotopes and rock magnetic studies of a stalagmite from a cave in eastern Quintana Roo, northern Yucatan peninsula. In the past years, there has been increased interest in understanding the paleoclimatic and paleoenvironmental evolution of the Yucatan peninsula and northern Central America, investigating the relationships between climate variations and the development of the Maya civilization. In particular, the variations in regional precipitation and occurrence of several drought periods, which might have been related to the collapse of the Classic Maya period. Stable isotope data on speleothems from different sites in Yucatan and Central America have provided evidence on changes in precipitation, which have affected the Maya region. The stalagmite is ~47 cm long and about 4-5 cm wide at its base. It was collected from the Hilariós Well cave in Tulum, Quintana Roo. Magnetic susceptibility and geochemical analyses have been completed as part of the initial characterization of the stalagmite, with measurements taken every centimeter. Geochemical analyses have been carried out for x-ray fluorescence, with a Niton XRF analyzer. Magnetic susceptibility was determined with a Bartington MS2 instrument using the high resolution surface probe. Additional rock magnetic analyses include magnetic hysteresis loops and isothermal remanent magnetization (IRM) acquisition, and saturation IRM demagnetization, which have been measured with a MicroMag instrument. Hysteresis loops are diamagnetic, with small varying low-coercivity ferromagnetic components. The elemental compositions of major oxides and trace elements vary with depth. Calcium is the major element and displays a pattern of small amplitude fluctuations with a trend to lower values at the bottom, which are also shown in other elements such as barium. Silica and elements such as titanium and strontium are positively correlated and show an apparent cyclic pattern

  7. 10 CFR 61.13 - Technical analyses.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Technical analyses. 61.13 Section 61.13 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Licenses § 61.13 Technical analyses. The specific technical information must also include the following analyses...

  8. Automatic incrementalization of Prolog based static analyses

    DEFF Research Database (Denmark)

    Eichberg, Michael; Kahl, Matthias; Saha, Diptikalyan;

    2007-01-01

    Modem development environments integrate various static analyses into the build process. Analyses that analyze the whole project whenever the project changes are impractical in this context. We present an approach to automatic incrementalization of analyses that are specified as tabled logic prog...

  9. Preliminary experimental study of a carbon fiber array cathode

    Science.gov (United States)

    Li, An-kun; Fan, Yu-wei

    2016-08-01

    The preliminary experimental results of a carbon fiber array cathode for the magnetically insulated transmission line oscillator (MILO) operations are reported. When the diode voltage and diode current were 480 kV and 44 kA, respectively, high-power microwaves with a peak power of about 3 GW and a pulse duration of about 60 ns were obtained in a MILO device with the carbon fiber array cathode. The preliminary experimental results show that the shot-to-shot reproducibility of the diode current and the microwave power is stable until 700 shots. No obvious damage or deterioration can be observed in the carbon fiber surface morphology after 700 shots. Moreover, the cathode performance has no observable deterioration after 700 shots. In conclusion, the maintain-free lifetime of the carbon fiber array cathode is more than 700 shots. In this way, this carbon fiber array cathode offers a potential replacement for the existing velvet cathode.

  10. Tree STEM Reconstruction Using Vertical Fisheye Images: a Preliminary Study

    Science.gov (United States)

    Berveglieri, A.; Tommaselli, A. M. G.

    2016-06-01

    A preliminary study was conducted to assess a tree stem reconstruction technique with panoramic images taken with fisheye lenses. The concept is similar to the Structure from Motion (SfM) technique, but the acquisition and data preparation rely on fisheye cameras to generate a vertical image sequence with height variations of the camera station. Each vertical image is rectified to four vertical planes, producing horizontal lateral views. The stems in the lateral view are rectified to the same scale in the image sequence to facilitate image matching. Using bundle adjustment, the stems are reconstructed, enabling later measurement and extraction of several attributes. The 3D reconstruction was performed with the proposed technique and compared with SfM. The preliminary results showed that the stems were correctly reconstructed by using the lateral virtual images generated from the vertical fisheye images and with the advantage of using fewer images and taken from one single station.

  11. TREE STEM RECONSTRUCTION USING VERTICAL FISHEYE IMAGES: A PRELIMINARY STUDY

    Directory of Open Access Journals (Sweden)

    A. Berveglieri

    2016-06-01

    Full Text Available A preliminary study was conducted to assess a tree stem reconstruction technique with panoramic images taken with fisheye lenses. The concept is similar to the Structure from Motion (SfM technique, but the acquisition and data preparation rely on fisheye cameras to generate a vertical image sequence with height variations of the camera station. Each vertical image is rectified to four vertical planes, producing horizontal lateral views. The stems in the lateral view are rectified to the same scale in the image sequence to facilitate image matching. Using bundle adjustment, the stems are reconstructed, enabling later measurement and extraction of several attributes. The 3D reconstruction was performed with the proposed technique and compared with SfM. The preliminary results showed that the stems were correctly reconstructed by using the lateral virtual images generated from the vertical fisheye images and with the advantage of using fewer images and taken from one single station.

  12. Births: preliminary data for 2012.

    Science.gov (United States)

    Hamilton, Brady E; Martin, Joyce A; Ventura, Stephanie J

    2013-09-01

    Objectives-This report presents preliminary data for 2012 on births in the United States. U.S. data on births are shown by age, live-birth order, race, and Hispanic origin of mother. Data on marital status, cesarean delivery, preterm births, and low birthweight are also presented. Methods-Data in this report are based on 99.96% of 2012 births.Records for the few states with less than 100% of records received are weighted to independent control counts of all births received in state vital statistics offices in 2012. Comparisons are made with final 2011 data. Results-The preliminary number of births for the United States in 2012 was 3,952,937, essentially unchanged (not statistically significant) from 2011; the general fertility rate was 63.0 births per 1,000 women aged 15-44, down only slightly from 2011, after declining nearly 3% a year from 2007 through 2010. The number of births and fertility rate either declined or were unchanged for most race and Hispanic origin groups from 2011 to 2012; however, both the number of births and the fertility rate for Asian or Pacific Islander women rose in 2012 (7% and 4%, respectively). The birth rate for teenagers aged 15-19 was down 6% in 2012 (29.4 births per 1,000 teenagers aged 15-19), yet another historic low for the United States, with rates declining for younger and older teenagers and for nearly all race and Hispanic origin groups. The birth rate for women in their early 20s also declined in 2012, to a new record low of 83.1 births per 1,000 women. Birth rates for women in their 30s rose in 2012, as did the birth rate for women in their early 40s. The birth rate for women in their late 40s was unchanged. The nonmarital birth rate declined in 2012 (to 45.3 birth per 1,000 unmarried women aged 15-44), whereas the number of births to unmarried women rose 1% and the percentage of births to unmarried women was unchanged (at 40.7%). The cesarean delivery rate for the United States was unchanged in 2012 at 32.8%. The preterm

  13. Herbarium specimens show contrasting phenological responses to Himalayan climate.

    Science.gov (United States)

    Hart, Robbie; Salick, Jan; Ranjitkar, Sailesh; Xu, Jianchu

    2014-07-22

    Responses by flowering plants to climate change are complex and only beginning to be understood. Through analyses of 10,295 herbarium specimens of Himalayan Rhododendron collected by plant hunters and botanists since 1884, we were able to separate these responses into significant components. We found a lack of directional change in mean flowering time over the past 45 y of rapid warming. However, over the full 125 y of collections, mean flowering time shows a significant response to year-to-year changes in temperature, and this response varies with season of warming. Mean flowering advances with annual warming (2.27 d earlier per 1 °C warming), and also is delayed with fall warming (2.54 d later per 1 °C warming). Annual warming may advance flowering through positive effects on overwintering bud formation, whereas fall warming may delay flowering through an impact on chilling requirements. The lack of a directional response suggests that contrasting phenological responses to temperature changes may obscure temperature sensitivity in plants. By drawing on large collections from multiple herbaria, made over more than a century, we show how these data may inform studies even of remote localities, and we highlight the increasing value of these and other natural history collections in understanding long-term change.

  14. Preliminary Design Through Graphs: A Tool for Automatic Layout Distribution

    Directory of Open Access Journals (Sweden)

    Carlo Biagini

    2015-02-01

    Full Text Available Diagrams are essential in the preliminary stages of design for understanding distributive aspects and assisting the decision-making process. By drawing a schematic graph, designers can visualize in a synthetic way the relationships between many aspects: functions and spaces, distribution of layouts, space adjacency, influence of traffic flows within a facility layout, and so on. This process can be automated through the use of modern Information and Communication Technologies tools (ICT that allow the designers to manage a large quantity of information. The work that we will present is part of an on-going research project into how modern parametric software influences decision-making on the basis of automatic and optimized layout distribution. The method involves two phases: the first aims to define the ontological relation between spaces, with particular reference to a specific building typology (rules of aggregation of spaces; the second entails the implementation of these rules through the use of specialist software. The generation of ontological relations begins with the collection of data from historical manuals and analyses of case studies. These analyses aim to generate a “relationship matrix” based on preferences of space adjacency. The phase of implementing the previously defined rules is based on the use of Grasshopper to analyse and visualize different layout configurations. The layout is generated by simulating a process involving the collision of spheres, which represents specific functions of the design program. The spheres are attracted or rejected as a function of the relationships matrix, as defined above. The layout thus obtained will remain in a sort of abstract state independent of information about the exterior form, but will still provide a useful tool for the decision-making process. In addition, preliminary results gathered through the analysis of case studies will be presented. These results provide a good variety

  15. Probabilistic evaluation of scenarios in long-term safety analyses. Results of the project ISIBEL; Probabilistische Bewertung von Szenarien in Langzeitsicherheitsanalysen. Ergebnisse des Vorhabens ISIBEL

    Energy Technology Data Exchange (ETDEWEB)

    Buhmann, Dieter; Becker, Dirk-Alexander; Laggiard, Eduardo; Ruebel, Andre; Spiessl, Sabine; Wolf, Jens

    2016-07-15

    In the frame of the project ISIBEL deterministic analyses on the radiological consequences of several possible developments of the final repository were performed (VSG: preliminary safety analysis of the site Gorleben). The report describes the probabilistic evaluation of the VSG scenarios using uncertainty and sensitivity analyses. It was shown that probabilistic analyses are important to evaluate the influence of uncertainties. The transfer of the selected scenarios in computational cases and the used modeling parameters are discussed.

  16. Preliminary study of the mite community structure in different black truffle producing soils

    Directory of Open Access Journals (Sweden)

    Mikel Queralt

    2014-08-01

    Full Text Available Aims of the study: The goals of this paper are to provide preliminary data on the composition of the mite community in truffle-producing soils (both wild and plantations; and to elucidate those species which may interact with the black truffle life cycle.Area of study: The study was carried out in two black truffle productive zones in Navarra (Spain, in four different plantations and five wild production areas.Material and Methods: Fauna was extracted using Berlese Tullgren funnels. Animals were separated into taxonomic groups, and mites were identified. To analyse the composition and community structure of the different habitats, parameters such as abundance, species richness, and Shanon Weiner diversity index (H’ were calculated.Main results: A total of 305 mites were recognized, belonging to 58 species representing the three major taxonomic groups (Oribatida, Prostigmata, Mesostigmata.Research highlights: The results show a possible trend towards wild areas having greater diversity and species richness than plantations. Furthermore, community analysis shows differences in species compositions among different study areas, and oribatid mites always exhibit the highest relative abundance and species richness.Keywords: Acari; Tuber melanosporum; Oribatida; Mesostigmata; Prostigmata; truffle orchards. 

  17. The genetic variability of the Podolica cattle breed from the Gargano area. Preliminary results

    Directory of Open Access Journals (Sweden)

    Dario Cianci

    2010-01-01

    Full Text Available The Podolica cattle breed is autochthonous of Southern Italy and denoted by its particular rusticity. This study presents the preliminary results of the genetic characterization of the Podolica breed using DNA STR markers. A total of 20 microsatellite loci were analysed in 79 individuals reared in the Gargano area. Number of polymorphisms, allele fre- quencies, deviations from Hardy-Weinberg proportions, linkage disequilibrium between loci and genetic similarities between animals were calculated. The results showed a high deficiency of heterozygotes, the observed mean of het- erozygosis being 0.449, whereas the expected mean was 0.766. Many markers showed also deviations from the Hardy- Weinberg proportions and significant linkage disequilibrium between loci. However the genetic similarity within the pop- ulation was low (0.281 and the average number of alleles per locus was high (10, representing a high genetic vari- ability. In order to explain these results, a stratification of the breed in sub-populations with a high interior genetic homo- geneity but markedly differentiated one from each other could be hypothesized; this situation probably derived from non- random mating within each herd (consanguinity and from the lack of exchange of genetic material between the herds. A further study is needed on a wider sample and extending the analysis to FAO-ISAG microsatellite panel in order to con- firm this hypothesis. This could eventually provide the information necessary for the correct management of the repro- ductive schemes and for genomic traceability of meat production.

  18. A Preliminary Evaluation of the Physiological Mechanisms of Action for Sleep Restriction Therapy

    Directory of Open Access Journals (Sweden)

    Annie Vallières

    2013-01-01

    Full Text Available Our objective was to investigate the physiological mechanisms involved in the sleep restriction treatment of insomnia. A multiple baseline across subjects design was used. Sleep of five participants suffering from insomnia was assessed throughout the experimentation by sleep diaries and actigraphy. Ten nights of polysomnography were conducted over five occasions. The first two-night assessment served to screen for sleep disorders and to establish a baseline for dependent measures. Three assessments were undertaken across the treatment interval, with the fifth and last one coming at follow-up. Daily cortisol assays were obtained. Sleep restriction therapy was applied in-lab for the first two nights of treatment and was subsequently supervised weekly. Interrupted time series analyses were computed on sleep diary data and showed a significantly decreased wake time, increased sleep efficiency, and decreased total sleep time. Sleepiness at night seems positively related to sleep variables, polysomnography data suggest objective changes mainly for stage 2, and power spectral analysis shows a decrease in beta-1 and -2 powers for the second night of treatment. Cortisol levels seem to be lower during treatment. These preliminary results confirm part of the proposed physiological mechanisms and suggest that sleep restriction contributes to a rapid decrease in hyperarousal insomnia.

  19. Preliminary studies for a new antibiotic from the marine mollusk Melo melo (Lightfoot, 1786)

    Institute of Scientific and Technical Information of China (English)

    Samuthirapandian Ravichandran; Kumaresan M

    2011-01-01

    Objective:To search for new bioactive compounds from marine mollusksMelo melo (M. melo). Methods:Preliminary work for bioactive compound was identified by using disc diffusion methods against human pathogens. Further analyses of compound were done by usingTLC, SDS-PAGE. And also estimate the amount of protein in the samples by following Biuret method.Results:In antibacterial activity the maximum diameter of 24 mm zone of inhibition was recorded againstKlebsiella pneumoniae (K. pneumoniae) strain of the mucus extract and minimum zone of inhibition of 11 mm was observed inSalmonella typhi (S. typhi) strain of body tissue extract. The antifungal activity of the extraction shows maximum activity against Trichophyton mentagarophytes (T. mentagarophytes) (14mm) and minimum activity was recorded inAspergillus flavus (A. flavus) (11 mm). The extract of mucus, nerve tissue, body tissue and kidney that showed antimicrobial activity was subjected toTLC to determine the presence of the peptides and amide groups, and also subjected toSDS-PAGE to estimate the molecular weight of proteins in a clear band were detected in the gel that represented kidney, body tissue, brain and mucus represent14, 17, 22, 45 kDa.Conclusions: The extracts from marine mollusksM. melo is the potential source of producing bioactive compounds against human pathogens and can be used for synthesis of new drugs.

  20. Preliminary Iron Distribution on Vesta

    Science.gov (United States)

    Mittlefehldt, David W.; Mittlefehldt, David W.

    2013-01-01

    The distribution of iron on the surface of the asteroid Vesta was investigated using Dawn's Gamma Ray and Neutron Detector (GRaND) [1,2]. Iron varies predictably with rock type for the howardite, eucrite, and diogenite (HED) meteorites, thought to be representative of Vesta. The abundance of Fe in howardites ranges from about 12 to 15 wt.%. Basaltic eucrites have the highest abundance, whereas, lower crustal and upper mantle materials (cumulate eucrites and diogenites) have the lowest, and howardites are intermediate [3]. We have completed a mapping study of 7.6 MeV gamma rays produced by neutron capture by Fe as measured by the bismuth germanate (BGO) detector of GRaND [1]. The procedures to determine Fe counting rates are presented in detail here, along with a preliminary distribution map, constituting the necessary initial step to quantification of Fe abundances. We find that the global distribution of Fe counting rates is generally consistent with independent mineralogical and compositional inferences obtained by other instruments on Dawn such as measurements of pyroxene absorption bands by the Visual and Infrared Spectrometer (VIR) [4] and Framing Camera (FC) [5] and neutron absorption measurements by GRaND [6].

  1. EUPORIAS: plans and preliminary results

    Science.gov (United States)

    Buontempo, C.

    2013-12-01

    Recent advances in our understanding and ability to forecast climate variability have meant that skilful predictions are beginning to be routinely made on seasonal to decadal (s2d) timescales. Such forecasts have the potential to be of great value to a wide range of decision-making, where outcomes are strongly influenced by variations in the climate. In 2012 the European Commission funded EUPORIAS, a four year long project to develop prototype end-to-end climate impact prediction services operating on a seasonal to decadal timescale, and assess their value in informing decision-making. EUPORIAS commenced on 1 November 2012, coordinated by the UK Met Office leading a consortium of 24 organisations representing world-class European climate research and climate service centres, expertise in impacts assessments and seasonal predictions, two United Nations agencies, specialists in new media, and commercial companies in climate-vulnerable sectors such as energy, water and tourism. The poster describes the setup of the project, its main outcome and some of the very preliminary results.

  2. Preliminary results of ANAIS-25

    CERN Document Server

    Amaré, J; Cuesta, C; García, E; Ginestra, C; Martínez, M; Oliván, M A; Ortigoza, Y; de Solórzano, A Ortiz; Pobes, C; Puimedón, J; Sarsa, M L; Villar, P; Villar, J A

    2013-01-01

    The ANAIS (Annual Modulation with NaI(Tl) Scintillators) experiment aims at the confirmation of the DAMA/LIBRA signal using the same target and technique at the Canfranc Underground Laboratory. 250 kg of ultrapure NaI(Tl) crystals will be used as a target, divided into 20 modules, each coupled to two photomultipliers. Two NaI(Tl) crystals of 12.5 kg each, grown by Alpha Spectra from a powder having a potassium level under the limit of our analytical techniques, form the ANAIS-25 set-up. The background contributions are being carefully studied and preliminary results are presented: their natural potassium content in the bulk has been quantified, as well as the uranium and thorium radioactive chains presence in the bulk through the discrimination of the corresponding alpha events by PSA, and due to the fast commissioning, the contribution from cosmogenic activated isotopes is clearly identified and their decay observed along the first months of data taking. Following the procedures established with ANAIS-0 and ...

  3. Stardust Interstellar Preliminary Examination (ISPE)

    Science.gov (United States)

    Westphal, A. J.; Allen, C.; Bajt, S.; Basset, R.; Bastien, R.; Bechtel, H.; Bleuet, P.; Borg, J.; Brenker F.; Bridges, J.

    2009-01-01

    In January 2006 the Stardust sample return capsule returned to Earth bearing the first solid samples from a primitive solar system body, C omet 81P/Wild2, and a collector dedicated to the capture and return o f contemporary interstellar dust. Both collectors were approximately 0.1m(exp 2) in area and were composed of aerogel tiles (85% of the co llecting area) and aluminum foils. The Stardust Interstellar Dust Col lector (SIDC) was exposed to the interstellar dust stream for a total exposure factor of 20 m(exp 2-) day during two periods before the co metary encounter. The Stardust Interstellar Preliminary Examination ( ISPE) is a three-year effort to characterize the collection using no ndestructive techniques. The ISPE consists of six interdependent proj ects: (1) Candidate identification through automated digital microsco py and a massively distributed, calibrated search (2) Candidate extr action and photodocumentation (3) Characterization of candidates thro ugh synchrotronbased FourierTranform Infrared Spectroscopy (FTIR), S canning XRay Fluoresence Microscopy (SXRF), and Scanning Transmission Xray Microscopy (STXM) (4) Search for and analysis of craters in f oils through FESEM scanning, Auger Spectroscopy and synchrotronbased Photoemission Electron Microscopy (PEEM) (5) Modeling of interstell ar dust transport in the solar system (6) Laboratory simulations of h ypervelocity dust impacts into the collecting media

  4. Brook trout (Salvelinus fontinalis extinction in small boreal lakes revealed by ephippia pigmentation: a preliminary analysis

    Directory of Open Access Journals (Sweden)

    Alexandre Bérubé Tellier

    2016-12-01

    Full Text Available Ephippium pigmentation is a plastic trait which can be related to a trade-off between visual predation pressure and better protection of cladoceran eggs against different types of stress. Experimental studies showed that planktivorous fish exert a greater predation pressure on individuals carrying darker ephippia, but little is known about the variation of ephippium pigmentation along gradients of fish predation pressure in natural conditions. For this study, our experimental design included four small boreal lakes with known fish assemblages. Two of the lakes have viable brook trout (Salvelinus fontinalis populations, whereas the other two lakes experienced brook trout extinctions during the 20th century. Cladoceran ephippia were extracted from sediment cores at layers corresponding to the documented post- extinction phase (1990's and from an older layer (1950's for which the brook trout population status is not known precisely. Our first objective was to determine whether brook trout extinction has a direct effect on both ephippium pigmentation and size. Our second objective was to give a preliminary assessment of the status of brook trout populations in the 1950's by comparing the variation in ephippia traits measured from this layer to those measured in the 1990's, for which the extinction patterns are well known. Cost-effective image analysis was used to assess variation in pigmentation levels in ephippia. This approach provided a proxy for the amount of melanin invested in each ephippium analysed. Our study clearly shows that ephippium pigmentation may represent a better indicator of the presence of fish predators than ephippium size, a trait that showed a less clear pattern of variation between lakes with and without fish. For the 1990's period, ephippia from fishless lakes were darker and showed a slight tendency to be larger than ephippia from lakes with brook trout. However, no clear differences in either ephippium size or pigmentation

  5. Preliminary investigation into the possible endocrine disrupting ...

    African Journals Online (AJOL)

    JTEkanem

    In this study, we quantified the effect of Bonny- light crude oil contaminated diet ... This preliminary result suggest that Bonny-Light crude oil may have the potential .... different components. Its exploration ... organisms found in crude oil polluted.

  6. 42 CFR 457.925 - Preliminary investigation.

    Science.gov (United States)

    2010-10-01

    ... (CONTINUED) STATE CHILDREN'S HEALTH INSURANCE PROGRAMS (SCHIPs) ALLOTMENTS AND GRANTS TO STATES Program Integrity § 457.925 Preliminary investigation. If the State agency receives a complaint of fraud or abuse...

  7. Preliminary design data package. Appendix C

    Energy Technology Data Exchange (ETDEWEB)

    1979-07-25

    The design requirements, design philosophy, method and assumptions, and preliminary computer-aided design of the Near-Term Hybrid Vehicle including its electric and heat power units, control equipment, transmission system, body, and overall vehicle characteristics are presented. (LCL)

  8. Preliminary project proposal : Missouri chutes, NE & IA

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This proposal is for the Missouri Chutes National Wildlife Refuge that would be in Nebraska and Iowa on the Missouri River. This preliminary project proposal focuses...

  9. Preliminary Survey of Ectoparasites Infesting Chickens (Gallus ...

    African Journals Online (AJOL)

    Preliminary Survey of Ectoparasites Infesting Chickens (Gallus domesticus) in. Four Areas of ... were identified with the following prevalences: the shaft louse, Menopon gallinae (8.1%), the chicken ..... Canis lupus familiaris in Mueang district ...

  10. Renewable Energy Park - Preliminary Feasibility & Engineering Report

    Energy Technology Data Exchange (ETDEWEB)

    Ariwite, Roderick [Fallon Paiute Shoshone Tribe, NV (United States)

    2015-07-31

    This "Renewable Energy Park - Preliminary Feasibility & Engineering Report" seeks to provide an overall assessment and review of renewable energy development opportunities on the Fallon Indian Reservation and Colony Lands.

  11. Preliminary Determination of Epicenters (PDE) Bulletin

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The NEIC global earthquake bulletin is called the Preliminary Determination of Epicenters or PDE, and is one of many discrete products in the ANSS Comprehensive...

  12. Alaska gold rush trails study: Preliminary draft

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Preliminary study draft, with maps, of seven gold rush trails in Alaska, to determine suitability for inclusion in the National Scenic Trails system and their...

  13. Tomato Fruits Show Wide Phenomic Diversity but Fruit Developmental Genes Show Low Genomic Diversity.

    Science.gov (United States)

    Mohan, Vijee; Gupta, Soni; Thomas, Sherinmol; Mickey, Hanjabam; Charakana, Chaitanya; Chauhan, Vineeta Singh; Sharma, Kapil; Kumar, Rakesh; Tyagi, Kamal; Sarma, Supriya; Gupta, Suresh Kumar; Kilambi, Himabindu Vasuki; Nongmaithem, Sapana; Kumari, Alka; Gupta, Prateek; Sreelakshmi, Yellamaraju; Sharma, Rameshwar

    2016-01-01

    Domestication of tomato has resulted in large diversity in fruit phenotypes. An intensive phenotyping of 127 tomato accessions from 20 countries revealed extensive morphological diversity in fruit traits. The diversity in fruit traits clustered the accessions into nine classes and identified certain promising lines having desirable traits pertaining to total soluble salts (TSS), carotenoids, ripening index, weight and shape. Factor analysis of the morphometric data from Tomato Analyzer showed that the fruit shape is a complex trait shared by several factors. The 100% variance between round and flat fruit shapes was explained by one discriminant function having a canonical correlation of 0.874 by stepwise discriminant analysis. A set of 10 genes (ACS2, COP1, CYC-B, RIN, MSH2, NAC-NOR, PHOT1, PHYA, PHYB and PSY1) involved in various plant developmental processes were screened for SNP polymorphism by EcoTILLING. The genetic diversity in these genes revealed a total of 36 non-synonymous and 18 synonymous changes leading to the identification of 28 haplotypes. The average frequency of polymorphism across the genes was 0.038/Kb. Significant negative Tajima'D statistic in two of the genes, ACS2 and PHOT1 indicated the presence of rare alleles in low frequency. Our study indicates that while there is low polymorphic diversity in the genes regulating plant development, the population shows wider phenotype diversity. Nonetheless, morphological and genetic diversity of the present collection can be further exploited as potential resources in future.

  14. Partial wave analyses of antiproton-proton annihilations in flight

    Energy Technology Data Exchange (ETDEWEB)

    Pychy, Julian; Koch, Helmut; Kopf, Bertram; Wiedner, Ulrich [Institut fuer Experimentalphysik I, Ruhr-Universitaet Bochum (Germany)

    2015-07-01

    To investigate important aspects for the upcoming PANDA experiment, partial wave analyses (PWA) of anti pp-annihilation processes are carried out using data from the Crystal Barrel (LEAR) experiment. A coupled channel analysis of the three reactions resulting in the final states K{sup +}K{sup -}π{sup 0}, π{sup 0}π{sup 0}η and π{sup 0}ηη at a beam momentum of 900 MeV/c is currently in progress. Preliminary results on the determination of resonance contributions and of the spin density matrix (SDM) of different light mesons are presented. The elements of the SDM provide important information about the production process. Furthermore, results of the analyses of the channels ωπ{sup 0}, ωπ{sup 0}η and π{sup +}π{sup -}π{sup 0}π{sup 0} are discussed. These studies are focused on the determination of the contributing angular momenta of the anti pp-system as well as of the SDM of the ω meson. Significant spin-alignment effects depending on the production angle are visible here. These results are compared with those for the φ(1020) in the K{sup +}K{sup -}π{sup 0} channel. All analyses have been performed using PAWIAN, a common, object-oriented and easy-to-use PWA software that is being developed at the Ruhr-Universitaet Bochum. This presentation summarizes recent activities of the Crystal Barrel (LEAR) Collaboration.

  15. Review of accident analyses of RB experimental reactor

    Directory of Open Access Journals (Sweden)

    Pešić Milan P.

    2003-01-01

    Full Text Available The RB reactor is a uranium fuel heavy water moderated critical assembly that has been put and kept in operation by the VTNCA Institute of Nuclear Sciences, Belgrade, Serbia and Montenegro, since April 1958. The first complete Safety Analysis Report of the RB reactor was prepared in 1961/62 yet, the first accident analysis had been made in late 1958 with the aim to examine a power transition and the total equivalent doses received by the staff during the reactivity accident that occurred on October 15, 1958. Since 1960, the RB reactor has been modified a few times. Beside the initial natural uranium metal fuel rods, new types of fuel (TVR-S types of Russian origin consisting of 2% enriched uranium metal and 80% enriched UO2 dispersed in aluminum matrix, have been available since 1962 and 1976 respectively. Modifications of the control and safety systems of the reactor were made occasionally. Special reactor cores were designed and constructed using all three types of fuel elements as well as the coupled fast-thermal ones. The Nuclear Safety Committee of the VINĆA Institute, an independent regulatory body, approved for usage all these modifications of the RB reactor on the basis of the Preliminary Safety Analysis Reports, which, beside proposed technical modifications and new regulation rules, included safety analyses of various possible accidents. A special attention was given (and a new safety methodology was proposed to thorough analyses of the design-based accidents related to the coupled fast-thermal cores that included central zones of the reactor filled by the fuel elements without any moderator. In this paper, an overview of some accidents, methodologies and computation tools used for the accident analyses of the RB reactor is given.

  16. Preliminary organizational culture scale focused on artifacts.

    Science.gov (United States)

    Bonavia, Tomas

    2006-12-01

    In this preliminary study, an Organizational Culture Scale was developed to assess cultural artifacts according to Schein's typology (1985). It includes a set of cultural artifacts to measure the extent to which an organization is more or less traditional. A total of 249 managers from a range of different companies responded to the items. Preliminary analysis yielded a one-dimensional scale with 14 items with high internal consistency and homogeneity.

  17. Preliminary organizational culture scale focused on artifacts

    OpenAIRE

    Bonavia, Tomas

    2006-01-01

    In this preliminary study, an organizational culture scale was developed to assess cultural artifacts according to Schein´s typology (1985). It includes a set of cultural artifacts to measure the extent to which an organization is more or less traditional. A total of 249 managers from a range of different companies responded to the items. Preliminary analysis yielded a one-dimensional scale with 14 items with high internal consistency and homogeneity.

  18. Preliminary heat flow map of Europe. Explanatory text

    Energy Technology Data Exchange (ETDEWEB)

    Cermak, V.; Hurtig, E.

    1977-08-08

    A preliminary heat flow map of Europe was prepared, based on data contained in 401 references. The map was prepared on a scale of 1:5,000,000 and shows broad-scale geological structure (e.g., platforms, shields, foredeeps) and specialized rock suites (ophiolites, volcanites). Primary faults and thrust faults are indicated, and contours showing the depth of crystalline basement are given. Heat flow is plotted using 10.0 mW/m/sup 2/ isotherms. The accompanying explanatory text describes data acquisition and techniques of correction, and discusses some implications of the results.

  19. Preliminary design of surrounding heliostat fields

    Energy Technology Data Exchange (ETDEWEB)

    Collado, Francisco J. [Zaragoza University, Dpto. de Ingenieria Mecanica, CPS-B, Maria de Luna 3, 50018 Zaragoza (Spain)

    2009-05-15

    Recently, the author has shown elsewhere a simplified model that allows quick evaluations of the annual overall energy collected by a surrounding heliostat field. This model is the combination of an analytical flux density function produced by a heliostat, developed by the own author, and an optimized mirror density distribution developed by University of Houston for the Solar One Project. As main conclusion of this previous work, it was recognized that such pseudo-continuous simplified model should not substitute much more accurate discrete evaluations, which manage thousands of individual heliostat coordinates. Here in this work, the difficulty of generating a preliminary discrete layout of a large number of heliostats is addressed. The main novelty is the direct definition of thousands of heliostat coordinates through basically two parameters i.e. a simplified blocking factor and an additional security distance. Such procedure, which was formerly theoretically suggested by the author, is put into practice here, showing examples and commenting their problems and advantages. Getting a previous set of thousands of heliostat coordinates would be a major first step in the complex process of designing solar power tower (SPT). (author)

  20. Preliminary Report on Coining of Targets

    Energy Technology Data Exchange (ETDEWEB)

    Davis, P; Wall, M; Hodge, N; Schwartz, A

    2004-07-27

    We were tasked with developing a coining technique that would evaluate the feasibility of using a pressing, or coining process to imprint a one-dimensional sinusoidal pattern onto a thin disk specimen. We performed finite element method simulations of the coining process, designed, built, and tested a coining apparatus and tested surrogate materials, and coined a sample of special nuclear material. The preliminary results were encouraging. The pressing of a 3-mm diameter by {approx}100 {micro}m thick disc to 500 pounds of pressure produced a flat part with a 1-{micro}m deep by 50-{micro}m period sine wave pattern covering all of the surface and thus demonstrated the method for replicating ultraprecision, mesoscale features onto a near-net-shape metallic blank. This coining technique is being developed to provide specialty processing for the manufacturing of difficult to machine, millimeter-size components made from materials that present hazardous conditions. The technology is versatile and can be used to imprint a wide range of features, or profiles into two opposing surfaces. The coining process requires a simple, conceivably hand held tool, which efficiently produces ultra-precision work pieces without the production of byproducts such as machining chips, or grinding swarf. It shows promise for use on ductile materials that cannot be precision machined with conventional single crystal diamond tooling. As a production process, it can be used to reduce manufacturing costs where large numbers of ultra-precision, repetitive designs are required.

  1. Mycodiversity in marine sediments contaminated by heavy metals: preliminary results

    Science.gov (United States)

    Zotti, Mirca; Carbone, Cristina; Cecchi, Grazia; Consani, Sirio; Cutroneo, Laura; Di Piazza, Simone; Gabutto, Giacomo; Greco, Giuseppe; Vagge, Greta; Capello, Marco

    2016-04-01

    Fungi represent the main decomposers of woody and herbaceous substrates in the marine ecosystems. To date there is a gap in the knowledge about the global diversity and distribution of fungi in marine habitats. On the basis of their biological diversity and their role in ecosystem processes, marine fungi may be considered one of the most attractive groups of organisms in modern biotechnology, e.g. ecotoxic metal bioaccumulation. Here we report the data about the first mycological survey in the metal contaminated coastal sediments of the Gromolo Bay. The latter is located in Ligurian Sea (Eastern Liguria, Italy) and is characterized by an enrichment of heavy metals due to pollution of Gromolo Torrent by acidic processes that interest Fe-Cu sulphide mine. 24 samples of marine sediments were collected along a linear plot in front of the shoreline in July 2015. Each sample was separated into three aliquot for mineralogical, chemical analyses and fungal characterization. The sediment samples are characterised by clay fractions (illite and chlorite), minerals of ophiolitic rocks (mainly serpentine, pyroxene and plagioclase) and quartz and are enriched some chemical elements of environmental importance (such as Cu, Zn, Pb, Cd, As). For fungal characterisation the sediment samples were inoculated in Petri dishes on different culture media (Malt Extract Agar and Rose Bengal) prepared with sea water and added with antibiotics. The inoculated dishes were incubated at 20°C in the dark for 28 days. Every week fungal growth was monitored counting the number of colonies. Later, the colonies were isolated in axenic culture for further molecular analysis. The mycodiversity evaluate on the basis of Colony Forming Units (CFU) and microfungal-morphotype characterised by macro-and micro-morphology. Until now on the 72 Petri dishes inoculated 112 CFU of filamentous fungi were counted, among these about 50 morphotypes were characterized. The quantitative results show a mean value of 4

  2. The quality improvement attitude survey: Development and preliminary psychometric characteristics.

    Science.gov (United States)

    Dunagan, Pamela B

    2017-08-22

    To report the development of a tool to measure nurse's attitudes about quality improvement in their practice setting and to examine preliminary psychometric characteristics of the Quality Improvement Nursing Attitude Scale. Human factors such as nursing attitudes of complacency have been identified as root causes of sentinel events. Attitudes of nurses concerning use of Quality and Safety Education for nurse's competencies can be most challenging to teach and to change. No tool has been developed measuring attitudes of nurses concerning their role in quality improvement. A descriptive study design with preliminary psychometric evaluation was used to examine the preliminary psychometric characteristics of the Quality Improvement Nursing Attitude Scale. Registered bedside clinical nurses comprised the sample for the study (n = 57). Quantitative data were analysed using descriptive statistics and Cronbach's alpha reliability. Total score and individual item statistics were evaluated. Two open-ended items were used to collect statements about nurses' feelings regarding their experience in quality improvement efforts. Strong support for the internal consistency reliability and face validity of the Quality Improvement Nursing Attitude Scale was found. Total scale scores were high indicating nurse participants valued Quality and Safety Education for Nurse competencies in practice. However, item-level statistics indicated nurses felt powerless when other nurses deviate from care standards. Additionally, the sample indicated they did not consistently report patient safety issues and did not have a feeling of value in efforts to improve care. Findings suggested organisational culture fosters nurses' reporting safety issues and feeling valued in efforts to improve care. Participants' narrative comments and item analysis revealed the need to generate new items for the Quality Improvement Nursing Attitude Scale focused on nurses' perception of their importance in quality and

  3. Sensitivity to Pain Traumatization Scale: development, validation, and preliminary findings

    Science.gov (United States)

    Katz, Joel; Fashler, Samantha R; Wicks, Claire; Pagé, M Gabrielle; Roosen, Kaley M; Kleiman, Valery; Clarke, Hance

    2017-01-01

    Background This article reports three studies describing the development and validation of the 12-item Sensitivity to Pain Traumatization Scale (SPTS-12). SPT refers to the anxiety-related cognitive, emotional, and behavioral reactions to pain that resemble the features of a traumatic stress reaction. Methods In Study 1, a preliminary set of 79 items was administered to 116 participants. The data were analyzed by using combined nonparametric and parametric item response theory resulting in a 12-item scale with a one-factor structure and good preliminary psychometric properties. Studies 2 and 3 assessed the factor structure and psychometric properties of the SPTS-12 in a community sample of 823 participants (268 with chronic pain and 555 pain-free) and a clinical sample of 345 patients (126 with chronic post-surgical pain, 92 with other nonsurgical chronic pain, and 127 with no chronic pain) at least 6 months after undergoing coronary artery bypass graft surgery, respectively. Results The final SPTS-12 derived from Study 1 comprised 12 items that discriminated between individuals with different levels of SPT, with the overall scale showing good to very good reliability and validity. The results from Studies 2 and 3 revealed a one-factor structure for chronic pain and pain-free samples, excellent reliability and concurrent validity, and moderate convergent and discriminant validity. Conclusion The results of the three studies provide preliminary evidence for the validity and reliability of the SPTS-12. PMID:28615962

  4. Preliminary design report for OTEC stationkeeping subsystems (SKSS)

    Energy Technology Data Exchange (ETDEWEB)

    1979-12-12

    Lockheed Ocean Systems with IMODCO prepared these preliminary designs for OTEC Stationkeeping Subsystems (SKSS) under contract to NOAA in support of the Department of Energy OTEC program. The results of Tasks III, V, and VI are presented in this design report. The report consists of five sections: introduction, preliminary designs for the multiple anchor leg (MAL) and tension anchor leg (TAL), costs and schedule, and conclusions. Extensive appendixes provide detailed descriptions of design methodology and include backup calculations and data to support the results presented. The objective of this effort is to complete the preliminary designs for the barge-MAL and Spar-TAL SKSS. A set of drawings is provided for each which show arrangements, configuration, component details, engineering description, and deployment plan. Loads analysis, performance assessment, and sensitivity to requirements are presented, together with the methodology employed to analyze the systems and to derive the results presented. Life cycle costs and schedule are prepared and compared on a common basis. Finally, recommendations for the Commercial Plant SKSS are presented for both platform types.

  5. Transcriptome characterization of Ishige okamurae (Phaeophyceae) shows strong environmental acclimation

    Institute of Scientific and Technical Information of China (English)

    QU Jieqiong; WANG Xumin; CHI Shan; WU Shuangxiu; SUN Jing; LIU Cui; CHEN Shengping; YU Jun; LIU Tao

    2014-01-01

    Ishige okamurae, with leathery branched narrow fronds consisting of cylindrical hairs, is the typical species of the genus Ishige, which is considered as one of the most basal genera in the phylogeny of the Phaeophy-ceae. Apart from great public interest from the evolutionary respect, more attention has been brought on the abundant bioactive compounds in I. okamurae for therapeutic or economic considerations, such as di-phlorethohydroxycarmalol and ishigoside. Yet little is known about related key genes or metabolic pathways involved in I. okamurae, which calls upon us to carry out global analyses of transcriptome by next generation sequencing. Altogether, we obtained 78 583 assembled scaffolds with N50 of 1 709 nucleotides, and 25 357 unigenes with significant BLAST matches (E-value cutoff of 10-5). In terms of characterization of the tran-scriptome of I. okamurae, we focused on anti-stress metabolic pathways and synthetic routes of bioactive compounds in an attempt to obtain a better understanding of the interactive organism-environment regula-tory networks. Pathway-based analysis helped us to deepen our comprehension of the interaction between I. okamurae and its surroundings, with MAPK signal pathway as an example. Furthermore, we discovered a wide range of novel putative functional proteins that could be of wide application, such as Rab family, using sequence-based transcriptome. In conclusion, transcriptome characterization of I. okamurae (Phaeophy-ceae) shows strong environmental acclimation.

  6. Congenital myotonic dystrophy can show congenital fiber type disproportion pathology.

    Science.gov (United States)

    Tominaga, Kayo; Hayashi, Yukiko K; Goto, Kanako; Minami, Narihiro; Noguchi, Satoru; Nonaka, Ikuya; Miki, Tetsuro; Nishino, Ichizo

    2010-04-01

    Congenital myotonic dystrophy (CDM) is associated with markedly expanded CTG repeats in DMPK. The presence of numerous immature fibers with peripheral halo is a characteristic feature of CDM muscles together with hypotrophy of type 1 fibers. Smaller type 1 fibers with no structural abnormality are a definitive criterion of congenital fiber type disproportion (CFTD). Nonetheless, we recently came across a patient who was genetically confirmed as CDM, but had been earlier diagnosed as CFTD when he was an infant. In this study, we performed clinical, pathological, and genetic analyses in infantile patients pathologically diagnosed as CFTD to evaluate CDM patients indistinguishable from CFTD. We examined CTG repeat expansion in DMPK in 28 infantile patients pathologically diagnosed as CFTD. Mutation screening of ACTA1 and TPM3 was performed, and we compared clinical and pathological findings of 20 CDM patients with those of the other cohorts. We identified four (14%) patients with CTG expansion in DMPK. ACTA1 mutation was identified in four (14%), and TPM3 mutation was found in two (7%) patients. Fiber size disproportion was more prominent in patients with ACTA1 or TPM3 mutations as compared to CFTD patients with CTG expansion. A further three patients among 20 CDM patients showed pathological findings similar to CFTD. From our results, CDM should be excluded in CFTD patients.

  7. 7 CFR 94.102 - Analyses available.

    Science.gov (United States)

    2010-01-01

    ... analyses for total ash, fat by acid hydrolysis, moisture, salt, protein, beta-carotene, catalase... monocytogenes, proteolytic count, psychrotrophic bacteria, Salmonella, Staphylococcus, thermoduric bacteria,...

  8. [Anne Arold. Kontrastive Analyse...] / Paul Alvre

    Index Scriptorium Estoniae

    Alvre, Paul, 1921-2008

    2001-01-01

    Arvustus: Arold, Anne. Kontrastive analyse der Wortbildungsmuster im Deutschen und im Estnischen (am Beispiel der Aussehensadjektive). Tartu, 2000. (Dissertationes philologiae germanicae Universitatis Tartuensis)

  9. International trade shows: Structure, strategy and performance of exhibitors at individual booths vs. joint booths

    DEFF Research Database (Denmark)

    Hansen, Kåre

    2000-01-01

    This paper examines differences in exhibitors who participate at international trade shows at joint booths and those who participate at individual booths. The structure, strategy, and trade show performance of exhibitors at joint booths and those at individual booths are analysed. The analysis of...... implications for exhibitors at interna-tional trade shows and export marketing programmes and other marketing programmes offering services to international trade show exhibitors....

  10. Preliminary results from NA52 strangelet search in Pb-Pb at 160 GeV/nucleon

    Energy Technology Data Exchange (ETDEWEB)

    Appelquist, G.; Bohm, C. [Stockholm Univ. (Sweden). Dept. of Physics; Baglin, C.; Bussiere, A. [Grenoble-1 Univ., 74 - Annecy (France). Lab. de Physique des Particules Elementaires; Beringer, J.; Borer, K.; Dittus, F.; Frei, D. [Bern Univ. (Switzerland). Lab. fuer Hochenergiephysik; Elsener, K. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Gorodetzky, Ph. [Centre National de la Recherche Scientifique (CNRS), 67 - Strasbourg (France)] [and others

    1995-12-31

    Strangelet search in Pb-Pb interaction at 160 GeV/c per nucleon is reported on. Preliminary analysis shows the ability of NA52 to reach sensitivity down to 3.10{sup -9} strangelet/interaction. (author)

  11. Assessing antiquity and turnover of terrestrial ecosystems in eastern North America using fossil pollen data: A preliminary study

    Energy Technology Data Exchange (ETDEWEB)

    Liu Yao; Jackson, Stephen T [Department of Botany and Program in Ecology, University of Wyoming (United States); Brewer, Simon [Department of Botany, University of Wyoming (United States); Williams, John W, E-mail: yliu11@uwyo.ed [Department of Geography and Center for Climatic Research, University of Wisconsin (United States)

    2010-03-15

    We explored formal approaches to identifying and interpreting the antiquity and turnover of terrestrial ecosystems in eastern North America using pollen records. Preliminary results of cluster analyses, receiver-operating characteristic (ROC) analyses, and likelihood estimation of ecosystem analog in a simple Bayesian model allow assessment of modern ecosystem antiquities and past ecosystem turnovers. Approaches discussed in this study thus provide a vehicle for further studies.

  12. PRELIMINARY FACTOR ANALYSIS OF VISUAL COGNITION AND MEMORY. STUDIES IN CINE-PSYCHOMETRY, FINAL REPORT, PART I.

    Science.gov (United States)

    SEIBERT, WARREN F.; AND OTHERS

    PRELIMINARY ANALYSES WERE UNDERTAKEN TO DETERMINE THE POTENTIAL CONTRIBUTION OF MOTION PICTURE FILMS TO FACTOR ANALYTIC STUDIES OF HUMAN INTELLECT. OF PRIMARY CONCERN WERE THE OPERATIONS OF COGNITION AND MEMORY, FORMING TWO OF THE FIVE OPERATION COLUMNS OF GUILFORD'S "STRUCTURE OF INTELLECT." THE CORE REFERENCE FOR THE STUDY WAS DEFINED…

  13. PRELIMINARY FACTOR ANALYSIS OF VISUAL COGNITION AND MEMORY. STUDIES IN CINE-PSYCHOMETRY, FINAL REPORT, PART I.

    Science.gov (United States)

    SEIBERT, WARREN F.; AND OTHERS

    PRELIMINARY ANALYSES WERE UNDERTAKEN TO DETERMINE THE POTENTIAL CONTRIBUTION OF MOTION PICTURE FILMS TO FACTOR ANALYTIC STUDIES OF HUMAN INTELLECT. OF PRIMARY CONCERN WERE THE OPERATIONS OF COGNITION AND MEMORY, FORMING TWO OF THE FIVE OPERATION COLUMNS OF GUILFORD'S "STRUCTURE OF INTELLECT." THE CORE REFERENCE FOR THE STUDY WAS DEFINED…

  14. Preliminary classification criteria for the cryoglobulinaemic vasculitis

    Science.gov (United States)

    De Vita, S; Soldano, F; Isola, M; Monti, G; Gabrielli, A; Tzioufas, A; Ferri, C; Ferraccioli, G F; Quartuccio, L; Corazza, L; De Marchi, G; Casals, M Ramos; Voulgarelis, M; Lenzi, M; Saccardo, F; Fraticelli, P; Mascia, M T; Sansonno, D; Cacoub, P; Tomsic, M; Tavoni, A; Pietrogrande, M; Zignego, A L; Scarpato, S; Mazzaro, C; Pioltelli, P; Steinfeld, S; Lamprecht, P; Bombardieri, S; Galli, M

    2011-01-01

    Background To develop preliminary classification criteria for the cryoglobulinaemic syndrome or cryoglobulinaemic vasculitis (CV). Methods Study part I developed a questionnaire for CV to be included in the formal, second part (study part II). Positivity of serum cryoglobulins was defined by experts as an essential condition for CV classification. In study part II, a core set of classification items (questionnaire, clinical and laboratory items, as agreed) was tested in three groups of patients and controls—that is, group A (new patients with the CV), group B (controls with serum cryoglobulins but lacking CV) and group C (controls without serum cryoglobulins but with features which can be observed in CV). Results In study part I (188 cases, 284 controls), a positive response to at least two of three selected questions showed a sensitivity of 81.9% and a specificity of 83.5% for CV. This questionnaire was employed and validated in study part II, which included 272 patients in group A and 228 controls in group B. The final classification criteria for CV, by pooling data from group A and group B, required the positivity of questionnaire plus clinical, questionnaire plus laboratory, or clinical plus laboratory items, or all the three, providing a sensitivity of 88.5% and a specificity of 93.6% for CV. By comparing data in group A versus group C (425 controls), the same classification criteria showed a sensitivity 88.5% and a specificity 97.0% for CV. Conclusion Classification criteria for CV were developed, and now need validation. PMID:21571735

  15. Preliminary Marketing Plan for Baby Carriage Online Store in Murmansk Region

    OpenAIRE

    Kirienko, Valeriia

    2016-01-01

    The goal of the thesis is to create a clear and understandable preliminary marketing plan based on both types of research: secondary and primary. The objective is to identify strategic marketing ideas based on different analyses and research. The chosen bibliography together with the thesis author’s own thoughts and experience are used in the thesis work. For secondary research, the author of the thesis uses information from Data Insight company. The firm provides the results of the survey...

  16. Preliminary Marketing Plan for Baby Carriage Online Store in Murmansk Region

    OpenAIRE

    Kirienko, Valeriia

    2016-01-01

    The goal of the thesis is to create a clear and understandable preliminary marketing plan based on both types of research: secondary and primary. The objective is to identify strategic marketing ideas based on different analyses and research. The chosen bibliography together with the thesis author’s own thoughts and experience are used in the thesis work. For secondary research, the author of the thesis uses information from Data Insight company. The firm provides the results of the survey...

  17. Fast and accurate methods for phylogenomic analyses

    Directory of Open Access Journals (Sweden)

    Warnow Tandy

    2011-10-01

    Full Text Available Abstract Background Species phylogenies are not estimated directly, but rather through phylogenetic analyses of different gene datasets. However, true gene trees can differ from the true species tree (and hence from one another due to biological processes such as horizontal gene transfer, incomplete lineage sorting, and gene duplication and loss, so that no single gene tree is a reliable estimate of the species tree. Several methods have been developed to estimate species trees from estimated gene trees, differing according to the specific algorithmic technique used and the biological model used to explain differences between species and gene trees. Relatively little is known about the relative performance of these methods. Results We report on a study evaluating several different methods for estimating species trees from sequence datasets, simulating sequence evolution under a complex model including indels (insertions and deletions, substitutions, and incomplete lineage sorting. The most important finding of our study is that some fast and simple methods are nearly as accurate as the most accurate methods, which employ sophisticated statistical methods and are computationally quite intensive. We also observe that methods that explicitly consider errors in the estimated gene trees produce more accurate trees than methods that assume the estimated gene trees are correct. Conclusions Our study shows that highly accurate estimations of species trees are achievable, even when gene trees differ from each other and from the species tree, and that these estimations can be obtained using fairly simple and computationally tractable methods.

  18. Evaluation of the Olympus AU-510 analyser.

    Science.gov (United States)

    Farré, C; Velasco, J; Ramón, F

    1991-01-01

    The selective multitest Olympus AU-510 analyser was evaluated according to the recommendations of the Comision de Instrumentacion de la Sociedad Española de Quimica Clinica and the European Committee for Clinical Laboratory Standards. The evaluation was carried out in two stages: an examination of the analytical units and then an evaluation in routine work conditions. The operational characteristics of the system were also studied.THE FIRST STAGE INCLUDED A PHOTOMETRIC STUDY: dependent on the absorbance, the inaccuracy varies between +0.5% to -0.6% at 405 nm and from -5.6% to 10.6% at 340 nm; the imprecision ranges between -0.22% and 0.56% at 405 nm and between 0.09% and 2.74% at 340 nm. Linearity was acceptable, apart from a very low absorbance for NADH at 340 nm; and the imprecision of the serum sample pipetter was satisfactory.TWELVE SERUM ANALYTES WERE STUDIED UNDER ROUTINE CONDITIONS: glucose, urea urate, cholesterol, triglycerides, total bilirubin, creatinine, phosphate, iron, aspartate aminotransferase, alanine aminotransferase and gamma-glutamyl transferase.The within-run imprecision (CV%) ranged from 0.67% for phosphate to 2.89% for iron and the between-run imprecision from 0.97% for total bilirubin to 7.06% for iron. There was no carryover in a study of the serum sample pipetter. Carry-over studies with the reagent and sample pipetters shows some cross contamination in the iron assay.

  19. Trend Analyses of Nitrate in Danish Groundwater

    Science.gov (United States)

    Hansen, B.; Thorling, L.; Dalgaard, T.; Erlandsen, M.

    2012-04-01

    This presentation assesses the long-term development in the oxic groundwater nitrate concentration and nitrogen (N) loss due to intensive farming in Denmark. Firstly, up to 20-year time-series from the national groundwater monitoring network enable a statistically systematic analysis of distribution, trends and trend reversals in the groundwater nitrate concentration. Secondly, knowledge about the N surplus in Danish agriculture since 1950 is used as an indicator of the potential loss of N. Thirdly, groundwater recharge CFC (Chlorofluorocarbon) age determination allows linking of the first two dataset. The development in the nitrate concentration of oxic groundwater clearly mirrors the development in the national agricultural N surplus, and a corresponding trend reversal is found in groundwater. Regulation and technical improvements in the intensive farming in Denmark have succeeded in decreasing the N surplus by 40% since the mid 1980s while at the same time maintaining crop yields and increasing the animal production of especially pigs. Trend analyses prove that the youngest (0-15 years old) oxic groundwater shows more pronounced significant downward nitrate trends (44%) than the oldest (25-50 years old) oxic groundwater (9%). This amounts to clear evidence of the effect of reduced nitrate leaching on groundwater nitrate concentrations in Denmark. Are the Danish groundwater monitoring strategy obtimal for detection of nitrate trends? Will the nitrate concentrations in Danish groundwater continue to decrease or are the Danish nitrate concentration levels now appropriate according to the Water Framework Directive?

  20. Comparative analyses of bidirectional promoters in vertebrates

    Directory of Open Access Journals (Sweden)

    Taylor James

    2008-05-01

    Full Text Available Abstract Background Orthologous genes with deep phylogenetic histories are likely to retain similar regulatory features. In this report we utilize orthology assignments for pairs of genes co-regulated by bidirectional promoters to map the ancestral history of the promoter regions. Results Our mapping of bidirectional promoters from humans to fish shows that many such promoters emerged after the divergence of chickens and fish. Furthermore, annotations of promoters in deep phylogenies enable detection of missing data or assembly problems present in higher vertebrates. The functional importance of bidirectional promoters is indicated by selective pressure to maintain the arrangement of genes regulated by the promoter over long evolutionary time spans. Characteristics unique to bidirectional promoters are further elucidated using a technique for unsupervised classification, known as ESPERR. Conclusion Results of these analyses will aid in our understanding of the evolution of bidirectional promoters, including whether the regulation of two genes evolved as a consequence of their proximity or if function dictated their co-regulation.

  1. A new modular chemiluminescence immunoassay analyser evaluated.

    Science.gov (United States)

    Ognibene, A; Drake, C J; Jeng, K Y; Pascucci, T E; Hsu, S; Luceri, F; Messeri, G

    2000-03-01

    Thyrotropin (TSH), free thyroxine (fT4) and testosterone assays have been used as a probe to evaluate the performances of a new modular chemiluminescence (CL) immunoassay analyser, the Abbott Architect 2000. The evaluation was run in parallel on other systems that use CL as the detection reaction: DPC Immulite, Chiron Diagnostics ACS-180 and ACS Centaur (TSH functional sensitivity only). TSH functional sensitivity was 0.0012, 0.009, 0.033 and 0.039 mU/I for the Architect, Immulite, ACS Centaur and ACS-180, respectively. Testosterone functional sensitivity was 0.38, 3.7 and 2.0 nmol/l for Architect, Immulite and ACS-180, respectively. Good correlation was obtained between the ACS-180 and Architect for all assays. The Immulite correlation did not agree well with the Architect or ACS-180 for fT4 and testosterone but was in good agreement for TSH. Regarding fT4 and testosterone, equilibrium dialysis and isotopic dilution gas-chromatography mass-spectrometry (GC-MS) respectively were used as reference methods. For both within- and between-run precision, the Architect showed the best reproducibility for all three analytes (CV < 6%).

  2. Statistical analyses of a screen cylinder wake

    Science.gov (United States)

    Mohd Azmi, Azlin; Zhou, Tongming; Zhou, Yu; Cheng, Liang

    2017-02-01

    The evolution of a screen cylinder wake was studied by analysing its statistical properties over a streamwise range of x/d={10-60}. The screen cylinder was made of a stainless steel screen mesh of 67% porosity. The experiments were conducted in a wind tunnel at a Reynolds number of 7000 using an X-probe. The results were compared with those obtained in the wake generated by a solid cylinder. It was observed that the evolution of the statistics in the wake of the screen cylinder was different from that of a solid cylinder, reflecting the differences in the formation of the organized large-scale vortices in both wakes. The streamwise evolution of the Reynolds stresses, energy spectra and cross-correlation coefficients indicated that there exists a critical location that differentiates the screen cylinder wake into two regions over the measured streamwise range. The formation of the fully formed large-scale vortices was delayed until this critical location. Comparison with existing results for screen strips showed that although the near-wake characteristics and the vortex formation mechanism were similar between the two wake generators, variation in the Strouhal frequencies was observed and the self-preservation states were non-universal, reconfirming the dependence of a wake on its initial condition.

  3. Preliminary design study of the TMT Telescope structure system: overview

    Science.gov (United States)

    Usuda, Tomonori; Ezaki, Yutaka; Kawaguchi, Noboru; Nagae, Kazuhiro; Kato, Atsushi; Takaki, Junji; Hirano, Masaki; Hattori, Tomoya; Tabata, Masaki; Horiuchi, Yasushi; Saruta, Yusuke; Sofuku, Satoru; Itoh, Noboru; Oshima, Takeharu; Takanezawa, Takashi; Endo, Makoto; Inatani, Junji; Iye, Masanori; Sadjadpour, Amir; Sirota, Mark; Roberts, Scott; Stepp, Larry

    2014-07-01

    We present an overview of the preliminary design of the Telescope Structure System (STR) of Thirty Meter Telescope (TMT). NAOJ was given responsibility for the TMT STR in early 2012 and engaged Mitsubishi Electric Corporation (MELCO) to take over the preliminary design work. MELCO performed a comprehensive preliminary design study in 2012 and 2013 and the design successfully passed its Preliminary Design Review (PDR) in November 2013 and April 2014. Design optimizations were pursued to better meet the design requirements and improvements were made in the designs of many of the telescope subsystems as follows: 1. 6-legged Top End configuration to support secondary mirror (M2) in order to reduce deformation of the Top End and to keep the same 4% blockage of the full aperture as the previous STR design. 2. "Double Lower Tube" of the elevation (EL) structure to reduce the required stroke of the primary mirror (M1) actuators to compensate the primary mirror cell (M1 Cell) deformation caused during the EL angle change in accordance with the requirements. 3. M1 Segment Handling System (SHS) to be able to make removing and installing 10 Mirror Segment Assemblies per day safely and with ease over M1 area where access of personnel is extremely difficult. This requires semi-automatic sequence operation and a robotic Segment Lifting Fixture (SLF) designed based on the Compliance Control System, developed for controlling industrial robots, with a mechanism to enable precise control within the six degrees of freedom of position control. 4. CO2 snow cleaning system to clean M1 every few weeks that is similar to the mechanical system that has been used at Subaru Telescope. 5. Seismic isolation and restraint systems with respect to safety; the maximum acceleration allowed for M1, M2, tertiary mirror (M3), LGSF, and science instruments in 1,000 year return period earthquakes are defined in the requirements. The Seismic requirements apply to any EL angle, regardless of the

  4. Novel Algorithms for Astronomical Plate Analyses

    Indian Academy of Sciences (India)

    Rene Hudec; Lukas Hudec

    2011-03-01

    Powerful computers and dedicated software allow effective data mining and scientific analyses in astronomical plate archives. We give and discuss examples of newly developed algorithms for astronomical plate analyses, e.g., searches for optical transients, as well as for major spectral and brightness changes.

  5. Moving Crystal Slow-Neutron Wavelength Analyser

    DEFF Research Database (Denmark)

    Buras, B.; Kjems, Jørgen

    1973-01-01

    Experimental proof that a moving single crystal can serve as a slow-neutron wavelength analyser of special features is presented. When the crystal moves with a velocity h/(2 md) (h-Planck constant, m-neutron mass, d-interplanar spacing) perpendicular to the diffracting plane and the analysed...

  6. Moving Crystal Slow-Neutron Wavelength Analyser

    DEFF Research Database (Denmark)

    Buras, B.; Kjems, Jørgen

    1973-01-01

    Experimental proof that a moving single crystal can serve as a slow-neutron wavelength analyser of special features is presented. When the crystal moves with a velocity h/(2 md) (h-Planck constant, m-neutron mass, d-interplanar spacing) perpendicular to the diffracting plane and the analysed...

  7. Diversity of primary care systems analysed.

    NARCIS (Netherlands)

    Kringos, D.; Boerma, W.; Bourgueil, Y.; Cartier, T.; Dedeu, T.; Hasvold, T.; Hutchinson, A.; Lember, M.; Oleszczyk, M.; Pavlick, D.R.

    2015-01-01

    This chapter analyses differences between countries and explains why countries differ regarding the structure and process of primary care. The components of primary care strength that are used in the analyses are health policy-making, workforce development and in the care process itself (see Fig.

  8. ERIS: preliminary design phase overview

    Science.gov (United States)

    Kuntschner, Harald; Jochum, Lieselotte; Amico, Paola; Dekker, Johannes K.; Kerber, Florian; Marchetti, Enrico; Accardo, Matteo; Brast, Roland; Brinkmann, Martin; Conzelmann, Ralf D.; Delabre, Bernard A.; Duchateau, Michel; Fedrigo, Enrico; Finger, Gert; Frank, Christoph; Rodriguez, Fernando G.; Klein, Barbara; Knudstrup, Jens; Le Louarn, Miska; Lundin, Lars; Modigliani, Andrea; Müller, Michael; Neeser, Mark; Tordo, Sebastien; Valenti, Elena; Eisenhauer, Frank; Sturm, Eckhard; Feuchtgruber, Helmut; George, Elisabeth M.; Hartl, Michael; Hofmann, Reiner; Huber, Heinrich; Plattner, Markus P.; Schubert, Josef; Tarantik, Karl; Wiezorrek, Erich; Meyer, Michael R.; Quanz, Sascha P.; Glauser, Adrian M.; Weisz, Harald; Esposito, Simone; Xompero, Marco; Agapito, Guido; Antichi, Jacopo; Biliotti, Valdemaro; Bonaglia, Marco; Briguglio, Runa; Carbonaro, Luca; Cresci, Giovanni; Fini, Luca; Pinna, Enrico; Puglisi, Alfio T.; Quirós-Pacheco, Fernando; Riccardi, Armando; Di Rico, Gianluca; Arcidiacono, Carmelo; Dolci, Mauro

    2014-07-01

    The Enhanced Resolution Imager and Spectrograph (ERIS) is the next-generation adaptive optics near-IR imager and spectrograph for the Cassegrain focus of the Very Large Telescope (VLT) Unit Telescope 4, which will soon make full use of the Adaptive Optics Facility (AOF). It is a high-Strehl AO-assisted instrument that will use the Deformable Secondary Mirror (DSM) and the new Laser Guide Star Facility (4LGSF). The project has been approved for construction and has entered its preliminary design phase. ERIS will be constructed in a collaboration including the Max- Planck Institut für Extraterrestrische Physik, the Eidgenössische Technische Hochschule Zürich and the Osservatorio Astrofisico di Arcetri and will offer 1 - 5 μm imaging and 1 - 2.5 μm integral field spectroscopic capabilities with a high Strehl performance. Wavefront sensing can be carried out with an optical high-order NGS Pyramid wavefront sensor, or with a single laser in either an optical low-order NGS mode, or with a near-IR low-order mode sensor. Due to its highly sensitive visible wavefront sensor, and separate near-IR low-order mode, ERIS provides a large sky coverage with its 1' patrol field radius that can even include AO stars embedded in dust-enshrouded environments. As such it will replace, with a much improved single conjugated AO correction, the most scientifically important imaging modes offered by NACO (diffraction limited imaging in the J to M bands, Sparse Aperture Masking and Apodizing Phase Plate (APP) coronagraphy) and the integral field spectroscopy modes of SINFONI, whose instrumental module, SPIFFI, will be upgraded and re-used in ERIS. As part of the SPIFFI upgrade a new higher resolution grating and a science detector replacement are envisaged, as well as PLC driven motors. To accommodate ERIS at the Cassegrain focus, an extension of the telescope back focal length is required, with modifications of the guider arm assembly. In this paper we report on the status of the

  9. Primed neutrophil infiltrations into multiple organs in child physical abuse cases: A preliminary study.

    Science.gov (United States)

    Hayashi, Takahito; Nakamae, Takuma; Higo, Eri; Ikematsu, Kazuya; Ogata, Mamoru

    2017-01-01

    Physical abuse of the elderly induces a massive primed neutrophil infiltration into the lung and liver through chemotaxis by interleukin (IL)-8, similar to cases of traumatic or hemorrhagic shock. Here, we used immunohistochemical analyses to investigate this infiltration in cases of physically abused children. In addition, we examined the expression of neutrophil elastase (NE) as the inflammatory mediator and α1-antitrypsin (AAT) as the elastase inhibitor. The number of neutrophils in the abuse cases was increased significantly in the heart, lung, liver, and kidney, compared with that of control cases. IL-8-positive cells and NE-positive cells in all organs of abuse cases were significantly greater than those in control cases. Large quantities of oxidized AAT, which fails to inactivate NE and results in tissue damage, was detected in the liver of abuse cases. Neutrophil infiltration showed positive correlation with the degree of systemic accumulation of non-fatal injuries caused by repetitive abusive behavior. Although further investigation using more autopsy samples is necessary, results of our preliminary study indicate that massive neutrophil infiltration induced by IL-8 in multiple organs is a new complementary diagnostic indicator of physical abuse in children. Moreover, the demonstration of NE-positive cells and oxidized AAT provides firm evidence of tissue damage.

  10. The DEEP-South: Preliminary Photometric Results from the KMTNet-CTIO

    Science.gov (United States)

    Kim, Myung-Jin; Moon, Hong-Kyu; Choi, Young-Jun; Yim, Hong-Suh; Bae, Youngho; Roh, Dong-Goo; the DEEP-South Team

    2015-08-01

    The DEep Ecliptic Patrol of the Southern sky (DEEP-South) will not only conduct characterization of targeted asteroids and blind survey at the sweet spots, but also utilize data mining of small Solar System bodies in the whole KMTNet archive. As round-the-clock observation with the KMTNet is optimized for spin characterization of tumbling and slow-rotating bodies as it facilitates debiasing previously reported lightcurve observations. It is also most suitable for detection and rapid follow-up of Atens and Atiras, the “difficult objects” that are being discovered at lower solar elongations.For the sake of efficiency, we implemented an observation scheduler, SMART (Scheduler for Measuring Asteroids RoTation), designed to conduct follow-up observations in a timely manner. It automatically updates catalogs, generates ephemerides, checks priorities, prepares target lists, and sends a suite of scripts to site operators. We also developed photometric analysis software called ASAP (Asteroid Spin Analysis Package) that aids to find a set of appropriate comparison stars in an image, to derive spin parameters and reconstruct lightcurve simultaneously in a semi-automatic manner. In this presentation, we will show our preliminary results of time series analyses of a number of km-sized Potentially Hazardous Asteroids (PHAs), 5189 (1990 UQ), 12923 (1999 GK4), 53426 (1999 SL5), 136614 (1993 VA6), 385186 (1994 AW1), and 2000 OH from test runs in February and March 2015 at the KMTNet-CTIO.

  11. Preliminary spatiotemporal analysis of the association between socio-environmental factors and suicide.

    Science.gov (United States)

    Qi, Xin; Tong, Shilu; Hu, Wenbiao

    2009-10-01

    The seasonality of suicide has long been recognised. However, little is known about the relative importance of socio-environmental factors in the occurrence of suicide in different geographical areas. This study examined the association of climate, socioeconomic and demographic factors with suicide in Queensland, Australia, using a spatiotemporal approach. Seasonal data on suicide, demographic variables and socioeconomic indexes for areas in each Local Government Area (LGA) between 1999 and 2003 were acquired from the Australian Bureau of Statistics. Climate data were supplied by the Australian Bureau of Meteorology. A multivariable generalized estimating equation model was used to examine the impact of socio-environmental factors on suicide. The preliminary data analyses show that far north Queensland had the highest suicide incidence (e.g., Cook and Mornington Shires), while the south-western areas had the lowest incidence (e.g., Barcoo and Bauhinia Shires) in all the seasons. Maximum temperature, unemployment rate, the proportion of Indigenous population and the proportion of population with low individual income were statistically significantly and positively associated with suicide. There were weaker but not significant associations for other variables. Maximum temperature, the proportion of Indigenous population and unemployment rate appeared to be major determinants of suicide at a LGA level in Queensland.

  12. Crisis Response Strategy and Crisis Types Suitability: A Preliminary Study on MH370

    Directory of Open Access Journals (Sweden)

    Mohamad Ashari Noratikah

    2017-01-01

    Full Text Available In time of crisis, the organisation’s tactic in responding to the crisis according to its type/s may significantly affect the organisation’s effort to survive its reputational damages. The study of crisis response strategy (CRS requires further exploration within the Malaysian context, moreso with the greater and apparent use of social media as a platform for the organisation in crisis to reach out to its stakeholders. This preliminary paper studies the MH370 crisis in light of Coombs [1] Situational Crisis Communication Theory (SCCT. It aims to discuss the suitability of the CRS applied by Malaysia Airlines System (MAS with the crisis type/s that was/were experienced by the organisation. Hence, the need for this paper to investigate the crisis type/s of MH370 and examines the CRS applied by MAS by content analysing media statements that were disseminated directly to the organisation’s stakeholders on Facebook during the first day of the crisis. Results ultimately show an interesting analysis to the crisis type of MH370, and the suitability of the CRS applied by MAS for that matter.

  13. Design of a Regenerative Life Support System for a Moon Base. Preliminary Results.

    Science.gov (United States)

    Duatis Juarez, Jordi; Guirado, Víctor; Lasseur, Christophe

    NTE-SENER has finalised a study under an ESA contract, to define a preliminary system design of an European Module to provide Environmental Control and Life Support to a potential Moon base. The design is based on current Life Support System technologies under development in Europe (MELiSSA, GWRU, Sabatier Reactor and UTU) along with contamination and microbial detection technologies (ANITA, MIDASS). The ECLSS is sized to provide water, air and up to the 40 As a support to the study a simulator has been developed to analyse the energy, volume and mass and the flow rates and efficiencies of the different components. The study applied the basics of the ALISSE criteria to evaluate the technologies taking as a source the results of the simulations. Detailed models of the different technologies have been developed including feedback from the pilot designs. The results of the study have showed up opportunities of improvement and many points that need to be further investigated. The technologies used in the study are based on the MELiSSA Pilot Plant reactors implementation and the results could affect their design in the near fu-ture in aspects such as carbon recycling, irrigation methods, energy consumption, technologies involved, etc.

  14. New technologies and new performances of the JCMT radio-telescope: a preliminary design study

    Science.gov (United States)

    Mian, S.; De Lorenzi, S.; Ghedin, L.; Rampini, F.; Marchiori, G.; Craig, S.

    2012-09-01

    With a diameter of 15m the James Clerk Maxwell Telescope (JCMT) is the largest astronomical telescope in the world designed specifically to operate in the submillimeter wavelength region of the spectrum. It is situated close to the summit of Mauna Kea, Hawaii, at an altitude of 4092m. Its primary reflector currently consists of a steel geodesic supporting structure and pressed aluminium panels on a passive mount. The major issues of the present reflector are its thermal stability and its panels deterioration. A preliminary design study for the replacement of the JCMT antenna dish is here presented. The requested shape error for the new reflector is antenna performance in terms of both stiffness and thermal stability, so that the required surface accuracy of the primary can be achieved even by adopting a passive panels system. Moreover thanks to CFRP, a considerable weight reduction of the elevation structure can be attained. The performance of the proposed solution for the JCMT antenna has been investigated through FE analyses and the assessed deformation of the structure under different loading cases has been taken into account for subsequent error budgeting. Results show that the proposed solution is in line with the requested performance. With this new backing structure, the JCMT would have the largest CFRP reflector ever built.

  15. A Preliminary Study on Paleomagnetism and Rock Magnetism of Eclogite from the Maobei Area

    Institute of Scientific and Technical Information of China (English)

    Meng Xiaohong; Yu Qinfan; GuoYouzhao; Zhou Yaoxiu

    2007-01-01

    A preliminary study of paleomagnetism and rock magnetism has been done on 55 eclogite samples collected from the Chinese Continental Scientific Drilling (CCSD) site at the Maobei (毛北) area,Donghai (东海) County, Jiangsu (江苏) Province. Also the isothermal remanence, hysteresis loop, magnetic fabric, thermal susceptibility were measured, and analyses were made by electron-probe and scanning electric microscope on some samples synchronously. The result indicates that there are two groups of stable remanence, the normal and reversed magnetization. The remanence orientations are: D=94.3°, I=-29.1° and D=273.7°, I=15.4°, respectively. The magnetization intensity and the density of the samples which carry the normal magnetization are very different from those bearing reversed magnetization. The magnetic anisotropy is weak, and the minimum axis is hardly determined. The isothermal remanence and the hysteresis loop show that the magnetic carriers of the eclogite are likely SD (single domain) and PSD(pseudo-single domain) magnetite. According to the magnetic property, the cause of formation of magnetic carriers, the mechanism of the remanence, and the significance for the tectonics are discussed.

  16. Preliminary analysis of the Nocturnal Atmospheric Boundary Layer during the experimental campaign CIBA 2008

    Science.gov (United States)

    Yagüe, C.; Maqueda, G.; Ramos, D.; Sastre, M.; Viana, S.; Serrano, E.; Morales, G.; Ayarzagüena, B.; Viñas, C.; Sánchez, E.

    2009-04-01

    An Atmospheric Boundary Layer campaign was developed in Spain along June 2008 at the CIBA (Research Centre for the Lower Atmosphere) site which is placed on a fairly homogeneous terrain in the centre of an extensive plateau (41°49' N, 4°56' W). Different instrumentation at several levels was available on a new 10m meteorological mast, including temperature and humidity sensors, wind vanes and cup anemometers, as well as one sonic anemometer. Besides, two quartz-based microbarometers were installed at 50 and 100m on the main permanent 100m tower placed at CIBA. Three additional microbarometers were deployed on the surface on a triangular array of approximately 200 m side, and a tethered balloon was used in order to record vertical profiles of temperature, wind and humidity up to 1000m. Finally, a GRIMM particle monitor (MODEL 365), which can be used to continuously measure each six seconds simultaneously the PM10, PM2.5 and PM1 values, was deployed at 1.5m. This work will show some preliminary results from the campaign CIBA 2008, analysing the main physical processes present in the atmospheric Nocturnal Boundary Layer (NBL), the different stability periods observed and the corresponding turbulent parameters, as well as the coherent structures detected. The pressure perturbations measured from the surface and tower levels make possible to study the main wave parameters from wavelet transform, and compared the structures detected by the microbarometers with those detected in the wind and particles records.

  17. Preliminary assessment of landslide-induced wave hazards, Tidal Inlet, Glacier Bay National Park, Alaska

    Science.gov (United States)

    Wieczorek, Gerald F.; Jakob, Matthias; Motyka, Roman J.; Zirnheld, Sandra L.; Craw, Patricia

    2003-01-01

    A large potential rock avalanche above the northern shore of Tidal Inlet, Glacier Bay National Park, Alaska, was investigated to determine hazards and risks of landslide-induced waves to cruise ships and other park visitors. Field and photographic examination revealed that the 5 to 10 million cubic meter landslide moved between AD 1892 and 1919 after the retreat of Little Ice Age glaciers from Tidal Inlet by AD 1890. The timing of landslide movement and the glacial history suggest that glacial debuttressing caused weakening of the slope and that the landslide could have been triggered by large earthquakes of 1899-1900 in Yakutat Bay. Evidence of recent movement includes fresh scarps, back-rotated blocks, and smaller secondary landslide movements. However, until there is evidence of current movement, the mass is classified as a dormant rock slump. An earthquake on the nearby active Fairweather fault system could reactivate the landslide and trigger a massive rock slump and debris avalanche into Tidal Inlet. Preliminary analyses show that waves induced by such a landslide could travel at speeds of 45 to 50 m/s and reach heights up to 76 m with wave runups of 200 m on the opposite shore of Tidal Inlet. Such waves would not only threaten vessels in Tidal Inlet, but would also travel into the western arm of Glacier Bay endangering large cruise ships and their passengers.

  18. Preliminary Design and Analysis of the ARES Atmospheric Flight Vehicle Thermal Control System

    Science.gov (United States)

    Gasbarre, J. F.; Dillman, R. A.

    2003-01-01

    The Aerial Regional-scale Environmental Survey (ARES) is a proposed 2007 Mars Scout Mission that will be the first mission to deploy an atmospheric flight vehicle (AFV) on another planet. This paper will describe the preliminary design and analysis of the AFV thermal control system for its flight through the Martian atmosphere and also present other analyses broadening the scope of that design to include other phases of the ARES mission. Initial analyses are discussed and results of trade studies are presented which detail the design process for AFV thermal control. Finally, results of the most recent AFV thermal analysis are shown and the plans for future work are discussed.

  19. FES Training in Aging: interim results show statistically significant improvements in mobility and muscle fiber size

    Directory of Open Access Journals (Sweden)

    Helmut Kern

    2012-03-01

    Full Text Available Aging is a multifactorial process that is characterized by decline in muscle mass and performance. Several factors, including reduced exercise, poor nutrition and modified hormonal metabolism, are responsible for changes in the rates of protein synthesis and degradation that drive skeletal muscle mass reduction with a consequent decline of force generation and mobility functional performances. Seniors with normal life style were enrolled: two groups in Vienna (n=32 and two groups in Bratislava: (n=19. All subjects were healthy and declared not to have any specific physical/disease problems. The two Vienna groups of seniors exercised for 10 weeks with two different types of training (leg press at the hospital or home-based functional electrical stimulation, h-b FES. Demografic data (age, height and weight were recorded before and after the training period and before and after the training period the patients were submitted to mobility functional analyses and muscle biopsies. The mobility functional analyses were: 1. gait speed (10m test fastest speed, in m/s; 2. time which the subject needed to rise from a chair for five times (5x Chair-Rise, in s; 3. Timed –Up-Go- Test, in s; 4. Stair-Test, in s; 5. isometric measurement of quadriceps force (Torque/kg, in Nm/kg; and 6. Dynamic Balance in mm. Preliminary analyses of muscle biopsies from quadriceps in some of the Vienna and Bratislava patients present morphometric results consistent with their functional behaviors. The statistically significant improvements in functional testings here reported demonstrates the effectiveness of h-b FES, and strongly support h-b FES, as a safe home-based method to improve contractility and performances of ageing muscles.

  20. Radiocarbon analyses along the EDML ice core in Antarctica

    NARCIS (Netherlands)

    van de Wal, R.S.W.; Meijer, H.A.J.; van Rooij, M.; van der Veen, C.

    2007-01-01

    Samples, 17 in total, from the EDML core drilled at Kohnen station Antarctica are analysed for 14CO and 14CO2 with a dry-extraction technique in combination with accelerator mass spectrometry. Results of the in situ produced 14CO fraction show a very low concentration of in situ produced 14CO. Despi

  1. Radiocarbon analyses along the EDML ice core in Antarctica

    NARCIS (Netherlands)

    Van de Wal, R. S. W.; Meijer, H. A. J.; De Rooij, M.; Van der Veen, C.

    2007-01-01

    Samples, 17 in total, from the EDML core drilled at Kohnen station Antarctica are analysed for (CO)-C-14 and (CO2)-C-14 with a dry-extraction technique in combination with accelerator mass spectrometry. Results of the in situ produced (CO)-C-14 fraction show a very low concentration of in situ produ

  2. Hydrogen Gas Retention and Release from WTP Vessels: Summary of Preliminary Studies

    Energy Technology Data Exchange (ETDEWEB)

    Gauglitz, Phillip A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Bontha, Jagannadha R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Daniel, Richard C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Mahoney, Lenna A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Rassat, Scot D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Wells, Beric E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Bao, Jie [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Boeringa, Gregory K. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Buchmiller, William C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Burns, Carolyn A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Chun, Jaehun [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Karri, Naveen K. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Li, Huidong [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Tran, Diana N. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-07-01

    The Hanford Waste Treatment and Immobilization Plant (WTP) is currently being designed and constructed to pretreat and vitrify a large portion of the waste in the 177 underground waste storage tanks at the Hanford Site. A number of technical issues related to the design of the pretreatment facility (PTF) of the WTP have been identified. These issues must be resolved prior to the U.S. Department of Energy (DOE) Office of River Protection (ORP) reaching a decision to proceed with engineering, procurement, and construction activities for the PTF. One of the issues is Technical Issue T1 - Hydrogen Gas Release from Vessels (hereafter referred to as T1). The focus of T1 is identifying controls for hydrogen release and completing any testing required to close the technical issue. In advance of selecting specific controls for hydrogen gas safety, a number of preliminary technical studies were initiated to support anticipated future testing and to improve the understanding of hydrogen gas generation, retention, and release within PTF vessels. These activities supported the development of a plan defining an overall strategy and approach for addressing T1 and achieving technical endpoints identified for T1. Preliminary studies also supported the development of a test plan for conducting testing and analysis to support closing T1. Both of these plans were developed in advance of selecting specific controls, and in the course of working on T1 it was decided that the testing and analysis identified in the test plan were not immediately needed. However, planning activities and preliminary studies led to significant technical progress in a number of areas. This report summarizes the progress to date from the preliminary technical studies. The technical results in this report should not be used for WTP design or safety and hazards analyses and technical results are marked with the following statement: “Preliminary Technical Results for Planning – Not to be used for WTP Design

  3. Building an organ-specific carcinogenic database for SAR analyses.

    Science.gov (United States)

    Young, John; Tong, Weida; Fang, Hong; Xie, Qian; Pearce, Bruce; Hashemi, Ray; Beger, Richard; Cheeseman, Mitchell; Chen, James; Chang, Yuan-Chin; Kodell, Ralph

    2004-09-10

    FDA reviewers need a means to rapidly predict organ-specific carcinogenicity to aid in evaluating new chemicals submitted for approval. This research addressed the building of a database to use in developing a predictive model for such an application based on structure-activity relationships (SAR). The Internet availability of the Carcinogenic Potency Database (CPDB) provided a solid foundation on which to base such a model. The addition of molecular structures to the CPDB provided the extra ingredient necessary for SAR analyses. However, the CPDB had to be compressed from a multirecord to a single record per chemical database; multiple records representing each gender, species, route of administration, and organ-specific toxicity had to be summarized into a single record for each study. Multiple studies on a single chemical had to be further reduced based on a hierarchical scheme. Structural cleanup involved removal of all chemicals that would impede the accurate generation of SAR type descriptors from commercial software programs; that is, inorganic chemicals, mixtures, and organometallics were removed. Counterions such as Na, K, sulfates, hydrates, and salts were also removed for structural consistency. Structural modification sometimes resulted in duplicate records that also had to be reduced to a single record based on the hierarchical scheme. The modified database containing 999 chemicals was evaluated for liver-specific carcinogenicity using a variety of analysis techniques. These preliminary analyses all yielded approximately the same results with an overall predictability of about 63%, which was comprised of a sensitivity of about 30% and a specificity of about 77%. Copyright Taylor & Francis Inc.

  4. Expression of CD1d protein in human testis showing normal and abnormal spermatogenesis.

    Science.gov (United States)

    Adly, Mohamed A; Abdelwahed Hussein, Mahmoud-Rezk

    2011-05-01

    CD1d is a member of CD1 family of transmembrane glycoproteins, which represent antigen-presenting molecules. Immunofluorescent staining methods were utilized to examine expression pattern of CD1d in human testicular specimens. In testis showing normal spermatogenesis, a strong CD1d cytoplasmic expression was seen the Sertoli cells, spermatogonia, and Leydig cells. A moderate expression was observed in the spermatocytes. In testes showing maturation arrest, CD1d expression was strong in the Sertoli cells and weak in spermatogonia and spermatocytes compared to testis with normal spermatogenesis. In Sertoli cell only syndrome, CD1d expression was strong in the Sertoli and Leydig cells. This preliminary study displayed testicular infertility-related changes in CD1d expression. The ultrastructural changes associated with with normal and abnormal spermatogenesis are open for further investigations.

  5. Preliminary report on radiocarbon dating of cryptoendolithic microorganisms

    Science.gov (United States)

    Bonani, G.; Friedmann, E. I.; Ocampo-Friedmann, R.; McKay, C. P.; Woelfli, W.

    1988-01-01

    The existence of microbial communities living inside desert rocks has been reported by FRIEDMANN et al. (1967, 1976), first in rocks collected from the hot and dry Negev desert and later in rocks in the frigid Ross Desert of Southern Victoria Land, Antarctica. The extremely inhospitable climatic conditions in both places has led to the suggestion that these organisms have very low rates of metabolism and may, in addition, be very old (FRIEDMANN 1982). Our preliminary measurements showed a 14C deficiency indicating a carbon age in the order of magnitude of 10(3) years.

  6. Preliminary Results on Uncertainty Quantification for Pattern Analytics

    Energy Technology Data Exchange (ETDEWEB)

    Stracuzzi, David John [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Brost, Randolph [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Chen, Maximillian Gene [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Malinas, Rebecca [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Peterson, Matthew Gregor [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Phillips, Cynthia A. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Robinson, David G. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Woodbridge, Diane [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-09-01

    This report summarizes preliminary research into uncertainty quantification for pattern ana- lytics within the context of the Pattern Analytics to Support High-Performance Exploitation and Reasoning (PANTHER) project. The primary focus of PANTHER was to make large quantities of remote sensing data searchable by analysts. The work described in this re- port adds nuance to both the initial data preparation steps and the search process. Search queries are transformed from does the specified pattern exist in the data? to how certain is the system that the returned results match the query? We show example results for both data processing and search, and discuss a number of possible improvements for each.

  7. Preliminary study of superconducting bulk magnets for Maglev

    Science.gov (United States)

    Fujimoto, Hiroyuki; Kamijo, Hiroki

    Recent development shows that melt-processed YBaCuO (Y123) or Rare Earth (RE)123 superconductors have a high Jc at 77 K and high magnetic field, leading to high field application as a superconducting quasi-permanent bulk magnet with the liquid nitrogen refrigeration. One of the promising applications is a superconducting magnet for the magnetically levitated (Maglev) train. We discuss a superconducting bulk magnet for the Maglev train in the aspect of a preliminary design of the bulk magnet and also processing for (L)REBaCuO bulk superconductors and their characteristic superconducting properties.

  8. Preliminary Analysis of ULPC Light Curves Using Fourier Decomposition Technique

    CERN Document Server

    Ngeow, Chow-Choong; Kanbur, Shashi; Barrett, Brittany; Lin, Bin

    2013-01-01

    Recent work on Ultra Long Period Cepheids (ULPCs) has suggested their usefulness as a distance indicator, but has not commented on their relationship as compared with other types of variable stars. In this work, we use Fourier analysis to quantify the structure of ULPC light curves and compare them to Classical Cepheids and Mira variables. Our preliminary results suggest that the low order Fourier parameters of ULPCs show a continuous trend defined by Classical Cepheids after the resonance around 10 days. However their Fourier parameters also overlapped with those from Miras, which make the classification of long period variable stars difficult based on the light curves information alone.

  9. Escherichia coli O26 IN RAW BUFFALO MILK: PRELIMINARY RESULTS

    Directory of Open Access Journals (Sweden)

    A. Rella

    2013-02-01

    Full Text Available Escherichia coli O26 is considered to be one of the most important food-borne pathogen. In this study, 120 buffalo milk samples collected in Lazio and in Apulia regions were tested for the presence of E. coli O26. One buffalo milk sample (0,8% tested positive for E. coli O26; the isolate was positive at the verocytotoxicity test and it showed resistance properties to different antimicrobial classes. These preliminary results highlight the need to monitor the foods of animal origin used for production and eaten by a wide range of persons, respect VTEC organism.

  10. Determinants of Trade Credit: A Preliminary Analysis on Construction Sector

    Directory of Open Access Journals (Sweden)

    Nicoleta Barbuta-Misu

    2016-07-01

    Full Text Available This paper introduces a preliminary analysis of the correlations between trade credit and some selected measures of financial performance for a sample of 958 firms acting in the construction sector. The examined period covers 2004-2013. The sample derived from Amadeus database contains firms that have sold and bought on credit. Results showed that larger firms offered and used more credit than counterparties. Firms offered and used in same time credit, but not in same level. Firms with higher return on assets and profit margin used and offered less credit from suppliers, respectively to clients. Moreover, more liquid firms used less trade payables.

  11. Design and preliminary testing of the RIC hybrid knee prosthesis.

    Science.gov (United States)

    Lenzi, T; Sensinger, J; Lipsey, J; Hargrove, L; Kuiken, T

    2015-08-01

    We present a novel hybrid knee prosthesis that uses a motor, transmission and control system only for active dynamics tasks, while relying on a spring/damper system for passive dynamics activities. Active dynamics tasks require higher torque, lower speed, and occur less frequently than passive dynamic activities. By designing the actuation system around active tasks alone, we achieved a lightweight design (1.7 Kg w/o battery) without sacrificing peak torque (85Nm repetitive). Preliminary tests performed by an able-bodied person using a bypass orthosis show that the hybrid knee can support reciprocal stairs ambulation with low electrical energy consumption.

  12. Cost-Benefit Analyses of Transportation Investments

    DEFF Research Database (Denmark)

    Næss, Petter

    2006-01-01

    This paper discusses the practice of cost-benefit analyses of transportation infrastructure investment projects from the meta-theoretical perspective of critical realism. Such analyses are based on a number of untenable ontological assumptions about social value, human nature and the natural......-to-pay investigations. Accepting the ontological and epistemological assumptions of cost-benefit analysis involves an implicit acceptance of the ethical and political values favoured by these assumptions. Cost-benefit analyses of transportation investment projects tend to neglect long-term environmental consequences...

  13. Level II Ergonomic Analyses, Dover AFB, DE

    Science.gov (United States)

    1999-02-01

    IERA-RS-BR-TR-1999-0002 UNITED STATES AIR FORCE IERA Level II Ergonomie Analyses, Dover AFB, DE Andrew Marcotte Marilyn Joyce The Joyce...Project (070401881, Washington, DC 20503. 1. AGENCY USE ONLY (Leave blank) 2. REPORT DATE 4. TITLE AND SUBTITLE Level II Ergonomie Analyses, Dover...1.0 INTRODUCTION 1-1 1.1 Purpose Of The Level II Ergonomie Analyses : 1-1 1.2 Approach 1-1 1.2.1 Initial Shop Selection and Administration of the

  14. Text Mining of the Classical Medical Literature for Medicines That Show Potential in Diabetic Nephropathy

    Directory of Open Access Journals (Sweden)

    Lei Zhang

    2014-01-01

    Full Text Available Objectives. To apply modern text-mining methods to identify candidate herbs and formulae for the treatment of diabetic nephropathy. Methods. The method we developed includes three steps: (1 identification of candidate ancient terms; (2 systemic search and assessment of medical records written in classical Chinese; (3 preliminary evaluation of the effect and safety of candidates. Results. Ancient terms Xia Xiao, Shen Xiao, and Xiao Shen were determined as the most likely to correspond with diabetic nephropathy and used in text mining. A total of 80 Chinese formulae for treating conditions congruent with diabetic nephropathy recorded in medical books from Tang Dynasty to Qing Dynasty were collected. Sao si tang (also called Reeling Silk Decoction was chosen to show the process of preliminary evaluation of the candidates. It had promising potential for development as new agent for the treatment of diabetic nephropathy. However, further investigations about the safety to patients with renal insufficiency are still needed. Conclusions. The methods developed in this study offer a targeted approach to identifying traditional herbs and/or formulae as candidates for further investigation in the search for new drugs for modern disease. However, more effort is still required to improve our techniques, especially with regard to compound formulae.

  15. Text mining of the classical medical literature for medicines that show potential in diabetic nephropathy.

    Science.gov (United States)

    Zhang, Lei; Li, Yin; Guo, Xinfeng; May, Brian H; Xue, Charlie C L; Yang, Lihong; Liu, Xusheng

    2014-01-01

    Objectives. To apply modern text-mining methods to identify candidate herbs and formulae for the treatment of diabetic nephropathy. Methods. The method we developed includes three steps: (1) identification of candidate ancient terms; (2) systemic search and assessment of medical records written in classical Chinese; (3) preliminary evaluation of the effect and safety of candidates. Results. Ancient terms Xia Xiao, Shen Xiao, and Xiao Shen were determined as the most likely to correspond with diabetic nephropathy and used in text mining. A total of 80 Chinese formulae for treating conditions congruent with diabetic nephropathy recorded in medical books from Tang Dynasty to Qing Dynasty were collected. Sao si tang (also called Reeling Silk Decoction) was chosen to show the process of preliminary evaluation of the candidates. It had promising potential for development as new agent for the treatment of diabetic nephropathy. However, further investigations about the safety to patients with renal insufficiency are still needed. Conclusions. The methods developed in this study offer a targeted approach to identifying traditional herbs and/or formulae as candidates for further investigation in the search for new drugs for modern disease. However, more effort is still required to improve our techniques, especially with regard to compound formulae.

  16. Fracturing and brittleness index analyses of shales

    Science.gov (United States)

    Barnhoorn, Auke; Primarini, Mutia; Houben, Maartje

    2016-04-01

    The formation of a fracture network in rocks has a crucial control on the flow behaviour of fluids. In addition, an existing network of fractures , influences the propagation of new fractures during e.g. hydraulic fracturing or during a seismic event. Understanding of the type and characteristics of the fracture network that will be formed during e.g. hydraulic fracturing is thus crucial to better predict the outcome of a hydraulic fracturing job. For this, knowledge of the rock properties is crucial. The brittleness index is often used as a rock property that can be used to predict the fracturing behaviour of a rock for e.g. hydraulic fracturing of shales. Various terminologies of the brittleness index (BI1, BI2 and BI3) exist based on mineralogy, elastic constants and stress-strain behaviour (Jin et al., 2014, Jarvie et al., 2007 and Holt et al., 2011). A maximum brittleness index of 1 predicts very good and efficient fracturing behaviour while a minimum brittleness index of 0 predicts a much more ductile shale behaviour. Here, we have performed systematic petrophysical, acoustic and geomechanical analyses on a set of shale samples from Whitby (UK) and we have determined the three different brittleness indices on each sample by performing all the analyses on each of the samples. We show that each of the three brittleness indices are very different for the same sample and as such it can be concluded that the brittleness index is not a good predictor of the fracturing behaviour of shales. The brittleness index based on the acoustic data (BI1) all lie around values of 0.5, while the brittleness index based on the stress strain data (BI2) give an average brittleness index around 0.75, whereas the mineralogy brittleness index (BI3) predict values below 0.2. This shows that by using different estimates of the brittleness index different decisions can be made for hydraulic fracturing. If we would rely on the mineralogy (BI3), the Whitby mudstone is not a suitable

  17. Hydrothermal Liquefaction Treatment Preliminary Hazard Analysis Report

    Energy Technology Data Exchange (ETDEWEB)

    Lowry, Peter P.; Wagner, Katie A.

    2015-08-31

    A preliminary hazard assessment was completed during February 2015 to evaluate the conceptual design of the modular hydrothermal liquefaction treatment system. The hazard assessment was performed in 2 stages. An initial assessment utilizing Hazard Identification and Preliminary Hazards Analysis (PHA) techniques identified areas with significant or unique hazards (process safety-related hazards) that fall outside of the normal operating envelope of PNNL and warranted additional analysis. The subsequent assessment was based on a qualitative What-If analysis. This analysis was augmented, as necessary, by additional quantitative analysis for scenarios involving a release of hazardous material or energy with the potential for affecting the public.

  18. Pipeline for macro- and microarray analyses

    Directory of Open Access Journals (Sweden)

    R. Vicentini

    2007-05-01

    Full Text Available The pipeline for macro- and microarray analyses (PMmA is a set of scripts with a web interface developed to analyze DNA array data generated by array image quantification software. PMmA is designed for use with single- or double-color array data and to work as a pipeline in five classes (data format, normalization, data analysis, clustering, and array maps. It can also be used as a plugin in the BioArray Software Environment, an open-source database for array analysis, or used in a local version of the web service. All scripts in PMmA were developed in the PERL programming language and statistical analysis functions were implemented in the R statistical language. Consequently, our package is a platform-independent software. Our algorithms can correctly select almost 90% of the differentially expressed genes, showing a superior performance compared to other methods of analysis. The pipeline software has been applied to 1536 expressed sequence tags macroarray public data of sugarcane exposed to cold for 3 to 48 h. PMmA identified thirty cold-responsive genes previously unidentified in this public dataset. Fourteen genes were up-regulated, two had a variable expression and the other fourteen were down-regulated in the treatments. These new findings certainly were a consequence of using a superior statistical analysis approach, since the original study did not take into account the dependence of data variability on the average signal intensity of each gene. The web interface, supplementary information, and the package source code are available, free, to non-commercial users at http://ipe.cbmeg.unicamp.br/pub/PMmA.

  19. Neural Spike-Train Analyses of the Speech-Based Envelope Power Spectrum Model

    Directory of Open Access Journals (Sweden)

    Varsha H. Rallapalli

    2016-10-01

    Full Text Available Diagnosing and treating hearing impairment is challenging because people with similar degrees of sensorineural hearing loss (SNHL often have different speech-recognition abilities. The speech-based envelope power spectrum model (sEPSM has demonstrated that the signal-to-noise ratio (SNRENV from a modulation filter bank provides a robust speech-intelligibility measure across a wider range of degraded conditions than many long-standing models. In the sEPSM, noise (N is assumed to: (a reduce S + N envelope power by filling in dips within clean speech (S and (b introduce an envelope noise floor from intrinsic fluctuations in the noise itself. While the promise of SNRENV has been demonstrated for normal-hearing listeners, it has not been thoroughly extended to hearing-impaired listeners because of limited physiological knowledge of how SNHL affects speech-in-noise envelope coding relative to noise alone. Here, envelope coding to speech-in-noise stimuli was quantified from auditory-nerve model spike trains using shuffled correlograms, which were analyzed in the modulation-frequency domain to compute modulation-band estimates of neural SNRENV. Preliminary spike-train analyses show strong similarities to the sEPSM, demonstrating feasibility of neural SNRENV computations. Results suggest that individual differences can occur based on differential degrees of outer- and inner-hair-cell dysfunction in listeners currently diagnosed into the single audiological SNHL category. The predicted acoustic-SNR dependence in individual differences suggests that the SNR-dependent rate of susceptibility could be an important metric in diagnosing individual differences. Future measurements of the neural SNRENV in animal studies with various forms of SNHL will provide valuable insight for understanding individual differences in speech-in-noise intelligibility.

  20. Lie algebraic analysis for the beam transport in the spherical electrostatic analyser

    Institute of Scientific and Technical Information of China (English)

    Lü Jian-Qin; Zhang Zhuo

    2007-01-01

    This paper uses the Lie algebraic method to analyse the charged particle trajectories in the spherical electrostatic analyser, and obtains the nonlinear solutions. The results show that the focusing abilities both in the x and y directions of the analyser are almost the same. Moreover, there exist dispersion effects in the x direction, and no dispersion effects in the y direction.

  1. Comparison with Russian analyses of meteor impact

    Energy Technology Data Exchange (ETDEWEB)

    Canavan, G.H.

    1997-06-01

    The inversion model for meteor impacts is used to discuss Russian analyses and compare principal results. For common input parameters, the models produce consistent estimates of impactor parameters. Directions for future research are discussed and prioritized.

  2. Analyse of Maintenance Cost in ST

    CERN Document Server

    Jenssen, B W

    2001-01-01

    An analyse has been carried out in ST concerning the total costs for the division. Even though the target was the maintenance costs in ST, the global budget over has been analysed. This has been done since there is close relation between investments & consolidation and the required level for maintenance. The purpose of the analyse was to focus on maintenance cost in ST as a ratio of total maintenance costs over the replacement value of the equipment, and to make some comparisons with other industries and laboratories. Families of equipment have been defined and their corresponding ratios calculated. This first approach gives us some "quantitative" measurements. This analyse should be combined with performance indicators (more "qualitative" measurements) that are telling us how well we are performing. This will help us in defending our budget, make better priorities, and we will satisfy the requirements from our external auditors.

  3. Understanding Human Error Based on Automated Analyses

    Data.gov (United States)

    National Aeronautics and Space Administration — This is a report on a continuing study of automated analyses of experiential textual reports to gain insight into the causal factors of human errors in aviation...

  4. Multivariate differential analyses of adolescents' experiences of ...

    African Journals Online (AJOL)

    and second order factor analyses, correlations, multiple regression, MANOVA, ... This does not mean that the high levels of violence, crime and abuse that are aggravated by socio economic factors such as poverty, unemployment, corruption, ...

  5. Anthocyanin analyses of Vaccinium fruit dietary supplements

    Science.gov (United States)

    Vaccinium fruit ingredients within dietary supplements were identified by comparisons with anthocyanin analyses of known Vaccinium profiles (demonstration of anthocyanin fingerprinting). Available Vaccinium supplements were purchased and analyzed; their anthocyanin profiles (based on HPLC separation...

  6. Economics show CO2 EOR potential in central Kansas

    Science.gov (United States)

    Dubois, M.K.; Byrnes, A.P.; Pancake, R.E.; Willhite, G.P.; Schoeling, L.G.

    2000-01-01

    Carbon dioxide (CO2) enhanced oil recovery (EOR) may be the key to recovering hundreds of millions of bbl of trapped oil from the mature fields in central Kansas. Preliminary economic analysis indicates that CO2 EOR should provide an internal rate of return (IRR) greater than 20%, before income tax, assuming oil sells for $20/bbl, CO2 costs $1/Mcf, and gross utilization is 10 Mcf of CO2/bbl of oil recovered. If the CO2 cost is reduced to $0.75/Mcf, an oil price of $17/bbl yields an IRR of 20%. Reservoir and economic modeling indicates that IRR is most sensitive to oil price and CO2 cost. A project requires a minimum recovery of 1,500 net bbl/acre (about 1 million net bbl/1-mile section) under a best-case scenario. Less important variables to the economics are capital costs and non-CO2 related lease operating expenses.

  7. En kritisk analyse af Leviathan & Samfundspagten

    OpenAIRE

    Bjelobrk, Aleksandar

    2006-01-01

    I denne rapport undersøges de politiske filosoffer Thomas Hobbes’ (1588-1679) og Jean-Jacques Rousseaus (1712-1778) udgaver af kontraktteorien. Med udgangspunkt i Leviathan del 1, Of Man og del 2, Of Common-Wealth af Thomas Hobbes (Hobbes 1991, oprindelig udgivet 1651) og Samfundspagten af Jean-Jacques Rousseau (Rousseau 1987, oprindelig udgivet 1762) klarlægges inkonsisten i deres teorier gennem to separate analyser. Med udgangspunkt i den fundne inkonsistens foretages en komparativ analyse,...

  8. Thermal Analyse sof Cross-Linked Polyethylene

    Directory of Open Access Journals (Sweden)

    Radek Polansky

    2007-01-01

    Full Text Available The paper summarizes results obtained during the structural analyses measurements (Differential Scanning Calorimetry DSC, Thermogravimetry TG, Thermomechanical analysis TMA and Fourier transform infrared spectroscopy FT-IR. The samples of cross-linked polyethylene cable insulation were tested via these analyses. The DSC and TG were carried out using simultaneous thermal analyzer TA Instruments SDT Q600 with connection of Fourier transform infrared spectrometer Nicolet 380. Thermomechanical analysis was carried out by TMA Q400EM TA Instruments apparatus.

  9. Cycle 0(CY1991) NLS trade studies and analyses report. Book 1: Structures and core vehicle

    Science.gov (United States)

    1992-01-01

    This report (SR-1: Structures, Trades, and Analysis), documents the Core Tankage Trades and analyses performed in support of the National Launch System (NLS) Cycle 0 preliminary design activities. The report covers trades that were conducted on the Vehicle Assembly, Fwd Skirt, LO2 Tank, Intertank, LH2 Tank, and Aft Skirt of the NLS Core Tankage. For each trade study, a two page executive summary and the detail trade study are provided. The trade studies contain study results, recommended changes to the Cycle 0 Baselines, and suggested follow on tasks to be performed during Cycle 1.

  10. Neoliberalism in education: Five images of critical analyses

    Directory of Open Access Journals (Sweden)

    Branislav Pupala

    2011-03-01

    Full Text Available The survey study brings information about the way that educational researchcopes with neoliberalism as a generalized form of social government in the currentwestern culture. It shows that neoliberalism is considered as a universal scope of otherchanges in the basic segments of education and those theoretical and critical analyses ofthis phenomenon represent an important part of production in the area of educationalresearch. It emphasizes the contribution of formation and development of the socalledgovernmental studies for comprehension of mechanisms and consequences ofneoliberal government of the society and shows how way the methodology of thesestudies helps to identify neoliberal strategies used in the regulation of social subjectsby education. There are five selected segments of critical analyses elaborated (fromthe concept of a lifelong learning, through preschool and university education to theeducation of teachers and PISA project that obviously show ideological and theoreticalcohesiveness of the education analysis through the scope of neoliberal governmentality.

  11. Break-even Analyses for Random Production and Demand Processes

    Institute of Scientific and Technical Information of China (English)

    Marcus Schweitzer

    2002-01-01

    Break-even analyses are often used as controlling instruments. Typically, they are applied to support decision processes or to gain information for the control of profits and sales. Firstly, the study gives an overview of the basic accounting systems. Secondly, the study shows possible ways of performing break-even analyses for a single-stage, make-to-order production in the case of random production and demand structures. To model these structures, queueing systems are employed. As a general result, we see that break-even analyses must always be performed taking into account an existing planning system. Under practical aspects, GI/G/1 systems turn out to map complex real situations realistically. From the examples given it can be concluded that one achieves different results compared with using a deterministic model even in the case of a simple, random effects approach. In particular, it is shown that stochastic modelling in general is helpful in avoiding incorrect decisions.

  12. Nonlinear Analyses of the Dynamic Properties of Hydrostatic Bearing Systems

    Institute of Scientific and Technical Information of China (English)

    LIU Wei(刘伟); WU Xiujiang(吴秀江); V.A. Prokopenko

    2003-01-01

    Nonlinear analyses of hydrostatic bearing systems are necessary to adequately model the fluid-solid interaction. The dynamic properties of linear and nonlinear analytical models of hydrostatic bearings are compared in this paper. The analyses were based on the determination of the aperiodic border of transient processes with external step loads. The results show that the dynamic properties can be most effectively improved by increasing the hydrostatic bearing crosspiece width and additional pocket volume in a bearing can extend the load range for which the transient process is aperiodic, but an additional restrictor and capacitor (RC) chain must be introduced for increasing damping. The nonlinear analyses can also be used to predict typical design parameters for a hydrostatic bearing.

  13. Traditional difference-score analyses of reasoning are flawed.

    Science.gov (United States)

    Heit, Evan; Rotello, Caren M

    2014-04-01

    Studies of the belief bias effect in syllogistic reasoning have relied on three traditional difference score measures: the logic index, belief index, and interaction index. Dube, Rotello, and Heit (2010, 2011) argued that the interaction index incorrectly assumes a linear receiver operating characteristic (ROC). Here, all three measures are addressed. Simulations indicated that traditional analyses of reasoning experiments are likely to lead to incorrect conclusions. Two new experiments examined the role of instructional manipulations on the belief bias effect. The form of the ROCs violated assumptions of traditional measures. In comparison, signal detection theory (SDT) model-based analyses were a better match for the form of the ROCs, and implied that belief bias and instructional manipulations are predominantly response bias effects. Finally, reanalyses of previous studies of conditional reasoning also showed non-linear ROCs, violating assumptions of traditional analyses. Overall, reasoning research using traditional measures is at risk of drawing incorrect conclusions.

  14. Preliminary designs: passive solar manufactured housing. Technical status report

    Energy Technology Data Exchange (ETDEWEB)

    1980-05-12

    The criteria established to guide the development of the preliminary designs are listed. Three preliminary designs incorporating direct gain and/or sunspace are presented. Costs, drawings, and supporting calculations are included. (MHR)

  15. Preliminary design package for Sunair SEC-601 solar collector

    Science.gov (United States)

    1978-01-01

    The preliminary design of the Owens-Illinois model Sunair SEC-601 tubular air solar collector is presented. Information in this package includes the subsystem design and development approaches, hazard analysis, and detailed drawings available as the preliminary design review.

  16. Thermo-Mechanical Analyses of the High Heat Flux Component for ITER Dual Functional Lithium Lead Test Blanket Module

    Institute of Scientific and Technical Information of China (English)

    CHEN Hongli; BAI Yunqing

    2009-01-01

    The finite element code ANSYS is used to calculate the temperature and stress distributions for the first wall of DFLL-TBM (dual functional lithium lead-test blanket module),for testing in ITER. Preliminary analyses indicate that not only the low temperature design rules,the well-known 3Sm rules, are satisfied for the first wall, but the additional high temperature structural design criteria for the creep damage limits and creep-ratcheting limits are met as well.

  17. 19 CFR 4.8 - Preliminary entry.

    Science.gov (United States)

    2010-04-01

    ... electronic equivalent of a complete Customs Form 1302 (Cargo Declaration), in the manner provided in § 4.7(b... 19 Customs Duties 1 2010-04-01 2010-04-01 false Preliminary entry. 4.8 Section 4.8 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE...

  18. 40 CFR 1042.210 - Preliminary approval.

    Science.gov (United States)

    2010-07-01

    ... specific provisions that apply for deterioration factors. Decisions made under this section are considered... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Preliminary approval. 1042.210 Section 1042.210 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION...

  19. Preliminary aerothermodynamic design method for hypersonic vehicles

    Science.gov (United States)

    Harloff, G. J.; Petrie, S. L.

    1987-01-01

    Preliminary design methods are presented for vehicle aerothermodynamics. Predictions are made for Shuttle orbiter, a Mach 6 transport vehicle and a high-speed missile configuration. Rapid and accurate methods are discussed for obtaining aerodynamic coefficients and heat transfer rates for laminar and turbulent flows for vehicles at high angles of attack and hypersonic Mach numbers.

  20. 25 CFR 11.1005 - Preliminary inquiry.

    Science.gov (United States)

    2010-04-01

    ... ORDER CODE Juvenile Offender Procedure § 11.1005 Preliminary inquiry. (a) If a minor is placed in... purpose of determining: (1) Whether probable cause exist to believe the minor committed the alleged.... (b) If a minor has been released to the parents, guardian or custodian, the children's court shall...

  1. Preliminary aspects of a qualitative research projection

    Directory of Open Access Journals (Sweden)

    Simona Haidau

    2012-12-01

    Full Text Available In this paper are presented preliminary aspects on the design of of qualitative research achieved by nongovernmental organizations in the North-East of Romȃnia. The research aims to identify attitudes, opinions and behaviors to nongovernmental organizations to implement public relations programs and campaigns.

  2. 15 CFR 270.101 - Preliminary reconnaissance.

    Science.gov (United States)

    2010-01-01

    ... establishment of a Team, the leader of the initial assessment will report his/her findings to the Director in a... the extent the Director deems it appropriate, the Director may conduct a preliminary reconnaissance at the site of a building failure. The Director may establish and deploy a Team to conduct the...

  3. Preliminary investigations of piezoelectric based LED luminary

    DEFF Research Database (Denmark)

    Nielsen, Dennis; Andersen, Michael A. E.; Meyer, Kaspar Sinding

    2011-01-01

    This paper presents a preliminary study of PT (Piezoelectric Transformer) based SMPS’s (Switch Mode Power Supplies) for LED luminary. The unique properties of PTs (efficiency, power density and EMI) make them highly suitable for this application. Power stage topologies, rectifiers circuits, modul...

  4. Preliminary Results on Charmed Meson Spectroscopy

    CERN Document Server

    Sarwar, S; Paolone, V S; Reyes, M; Anjos, J C; Yager, P M; Bediaga, I; Göbel, C; Magnin, J; De Miranda, J M; Pepe, I M; Dos Reis, A C; Simão, F R A; Carrillo, S; Casimiro, E; Méndez, H; Sánchez-Hernández, A; Uribe, C; Vásquez, F; Cinquini, L; Cumalat, J P; Ramírez, J E; O'Reilly, B; Vaandering, E W; Butler, J N; Cheung, H W K; Gaines, I; Garbincius, P H; Garren, L A; Gottschalk, E E; Gourlay, S A; Kasper, P H; Kreymer, A E; Kutschke, R; Bianco, S; Fabbri, Franco Luigi; Sarwar, S; Cawlfield, C; Kim, D Y; Park, K S; Rahimi, A; Gardner, R; Chung, Y S; Kang, J S; Ko, B R; Kwak, J W; Lee, K B; Myung, S S; Alimonti, G; Boschini, M; Brambilla, D; Caccianiga, B; Calandrino, A; D'Angelo, P; Di Corato, M; Dini, P; Giammarchi, M G; Inzani, P; Leveraro, F; Malvezzi, S; Menasce, D; Mezzadri, M; Milazzo, L; Moroni, L; Pedrini, D; Prelz, F; Rovere, M; Sala, A; Sala, S; Arena, V; Boca, G; Bonomi, G; Gianini, G; Liguori, G; Merlo, M; Pantea, D; Ratti, S P; Riccardi, C; Torre, P; Viola, L; Vitulo, P; Hernández, Pilar; López, A M; Méndez, L; Mirles, M A; Montiel, E; Olaya, D; Quinones, J; Rivera, C; Zhang-Mayaguez, Y; Copty, N K; Purohit, M; Cho, K; Handler, T; Engh, D; Johns, W E; Hosack, M; Nehring, M S; Sales, M; Sheldon, P D; Stenson, K; Webster, M S; Sheaff, M; Kwon, Y; Sarwar, Shahzad

    2001-01-01

    We report the preliminary measurement by the FOCUS Collaboration (E831 at Fermilab) of masses and widths of the L=1 charm mesons $D_2^{*0}$ and $D_2^{*+}$. The fit of the invariant mass distribution requires an additional term to account for a broad structure over background.

  5. A DESCRIPTIVE INDONESIAN GRAMMAR--PRELIMINARY EDITION.

    Science.gov (United States)

    DYEN, ISIDORE

    THIS PRELIMINARY EDITION COMPRISES A DESCRIPTIVE GRAMMAR OF INDONESIAN (BAHASA INDONESIA), THE OFFICIAL LANGUAGE OF THE REPUBLIC OF INDONESIA. THE THREE SECTIONS--PHONOLOGY, SYNTAX, AND MORPHOLOGY--PRESENT A COMPREHENSIVE LINGUISTIC ANALYSIS OF INDONESIAN, WITH OCCASIONAL CONTRASTIVE REFERENCE TO MALAY, JAVANESE, SUNDANESE, AND SUMATRAN. THIS…

  6. The Adaptation Gap Report - a Preliminary Assessment

    DEFF Research Database (Denmark)

    Alverson, Keith; Olhoff, Anne; Noble, Ian;

    This first Adaptation Gap report provides an equally sobering assessment of the gap between adaptation needs and reality, based on preliminary thinking on how baselines, future goals or targets, and gaps between them might be defined for climate change adaptation. The report focuses on gaps in de...... in developing countries in three important areas: finance, technology and knowledge....

  7. Tellurium in active volcanic environments: Preliminary results

    Science.gov (United States)

    Milazzo, Silvia; Calabrese, Sergio; D'Alessandro, Walter; Brusca, Lorenzo; Bellomo, Sergio; Parello, Francesco

    2014-05-01

    Tellurium is a toxic metalloid and, according to the Goldschmidt classification, a chalcophile element. In the last years its commercial importance has considerably increased because of its wide use in solar cells, thermoelectric and electronic devices of the last generation. Despite such large use, scientific knowledge about volcanogenic tellurium is very poor. Few previous authors report result of tellurium concentrations in volcanic plume, among with other trace metals. They recognize this element as volatile, concluding that volcanic gases and sulfur deposits are usually enriched with tellurium. Here, we present some results on tellurium concentrations in volcanic emissions (plume, fumaroles, ash leachates) and in environmental matrices (soils and plants) affected by volcanic emissions and/or deposition. Samples were collected at Etna and Vulcano (Italy), Turrialba (Costa Rica), Miyakejima, Aso, Asama (Japan), Mutnovsky (Kamchatka) at the crater rims by using common filtration techniques for aerosols (polytetrafluoroethylene filters). Filters were both eluted with Millipore water and acid microwave digested, and analyzed by inductively coupled plasma mass spectrometry (ICP-MS). Volcanic ashes emitted during explosive events on Etna and Copahue (Argentina) were analyzed for tellurium bulk composition and after leaching experiments to evaluate the soluble fraction of tellurium. Soils and leaves of vegetation were also sampled close to active volcanic vents (Etna, Vulcano, Nisyros, Nyiragongo, Turrialba, Gorely and Masaya) and investigated for tellurium contents. Preliminary results showed very high enrichments of tellurium in volcanic emissions comparing with other volatile elements like mercury, arsenic, thallium and bismuth. This suggests a primary transport in the volatile phase, probably in gaseous form (as also suggested by recent studies) and/or as soluble salts (halides and/or sulfates) adsorbed on the surface of particulate particles and ashes. First

  8. A PRELIMINARY STUDY OF STEREOSELECTIVITY OF MEFLOQUINE ENANTIOMERS IN RAT

    Directory of Open Access Journals (Sweden)

    E. Souri.

    1998-08-01

    Full Text Available Stereoselectivity of mefloquine enantiomers were studied in rats after oral administration of a single 50mg/Kg dose of the racemate. Pharmacokinetic parameters of (+-(RS-MFQ in blood and plasma showed no significant difference. The concentration, AUC , CLIF and VdlF of (+-(RS-enantiomerin blood were significantly higher than those for the (--(SR-enantiomer. Tlie results obtained from this study showed a reverse stereoselectivity of MFQ as compared with what reported for human. A very low amount of enantiomers excreted in urine and the excretion was not stereoselective. A preliminary study in different blood fractions showed that the accumulation of MFQ enantiomers in blood cells is stereoselective with a tendency of ( + -(RS-enatiomer for leukocytes and (--(SR-enantiomer for erythrocytes.

  9. Preliminary Rock Physics Characterization of Mississippian Carbonate Reservoir in Canada

    Science.gov (United States)

    Lee, M.; Keehm, Y.; Kim, H.

    2011-12-01

    The Mississippian formations in the Western Canada Sedimentary Basin are known to have large hydrocarbon resources. The Lodgepole formation is the most important reservoir for oil production in Daly and Virden fields. In this study, we performed preliminary reservoir characterization using rock physics modeling. We first delineated the Lodgepole formation by geological information, well-logs and core analysis data. Then, we conducted rock physics analyses such as GR-AI, DEM modeling, porosity-Vp, density-Vp, and porosity-permeability. We identified the Lodgepole formation has different porosity types, volume of shale, and the degree of fractures in difference intervals. In the upper part of the formation, we found that vuggy pores are well developed. Inter-particular porosity and fractures become significant as the depth increases. We found that the lower part can be divided into two groups by acoustic impedance. The prospective reservoir interval, one of the two groups, has higher fracture density, which can be identified by lower acoustic impedance. This result also implies that we could also use AVO analyses to delineate good reservoir intervals. In conclusion, rock physics modeling can be effectively applied to characterize the Lodgepole formation quantitatively with well-log and core analysis data. Acknowledgement: This work was supported by the Energy Resources R&D program of the Korea Institute of Energy Technology Evaluation and Planning (KETEP) grant funded by the Korea government Ministry of Knowledge Economy (No. 2009201030001A).

  10. System Synthesis in Preliminary Aircraft Design Using Statistical Methods

    Science.gov (United States)

    DeLaurentis, Daniel; Mavris, Dimitri N.; Schrage, Daniel P.

    1996-01-01

    This paper documents an approach to conceptual and early preliminary aircraft design in which system synthesis is achieved using statistical methods, specifically Design of Experiments (DOE) and Response Surface Methodology (RSM). These methods are employed in order to more efficiently search the design space for optimum configurations. In particular, a methodology incorporating three uses of these techniques is presented. First, response surface equations are formed which represent aerodynamic analyses, in the form of regression polynomials, which are more sophisticated than generally available in early design stages. Next, a regression equation for an Overall Evaluation Criterion is constructed for the purpose of constrained optimization at the system level. This optimization, though achieved in an innovative way, is still traditional in that it is a point design solution. The methodology put forward here remedies this by introducing uncertainty into the problem, resulting in solutions which are probabilistic in nature. DOE/RSM is used for the third time in this setting. The process is demonstrated through a detailed aero-propulsion optimization of a High Speed Civil Transport. Fundamental goals of the methodology, then, are to introduce higher fidelity disciplinary analyses to the conceptual aircraft synthesis and provide a roadmap for transitioning from point solutions to probabilistic designs (and eventually robust ones).

  11. Effect of the ultrasound-assisted preliminary maceration on the efficiency of the essential oil distillation from selected herbal raw materials.

    Science.gov (United States)

    Kowalski, Radosław; Kowalska, Grażyna; Jamroz, Jerzy; Nawrocka, Agnieszka; Metyk, Damian

    2015-05-01

    The objective of the study was the estimation of the ultrasound-assisted preliminary maceration effect on the efficiency of essential oil distillation and on its qualitative and quantitative composition. The experiment included analyses on three herbal materials, i.e. peppermint leaves (Mentha piperita L.), marjoram herb (Origanum majorana L.), and chamomile flowers (Chamomilla recutita (L.) Rauschert). The study showed that the application of preliminary water maceration of raw material, augmented with ultrasounds, had a statistically significant increasing effect on the amount of oil distilled, in the case of mint leaf from 1.32% to 1.46% v/w, and in the case of marjoram herb from 1.13% to 1.27% v/w. In the case of chamomile flowers no significant effect of ultrasound on the amount of oil obtained was observed. Generally, comparing the composition of essential oils obtained in the experiments with the requirements of the relevant standards no unfavourable effect of the distillation augmenting techniques applied was noted. Therefore, it should be expected that the studied distillates of volatile fractions will have the desired biological activity. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. VESPA: Very large-scale Evolutionary and Selective Pressure Analyses

    Directory of Open Access Journals (Sweden)

    Andrew E. Webb

    2017-06-01

    Full Text Available Background Large-scale molecular evolutionary analyses of protein coding sequences requires a number of preparatory inter-related steps from finding gene families, to generating alignments and phylogenetic trees and assessing selective pressure variation. Each phase of these analyses can represent significant challenges, particularly when working with entire proteomes (all protein coding sequences in a genome from a large number of species. Methods We present VESPA, software capable of automating a selective pressure analysis using codeML in addition to the preparatory analyses and summary statistics. VESPA is written in python and Perl and is designed to run within a UNIX environment. Results We have benchmarked VESPA and our results show that the method is consistent, performs well on both large scale and smaller scale datasets, and produces results in line with previously published datasets. Discussion Large-scale gene family identification, sequence alignment, and phylogeny reconstruction are all important aspects of large-scale molecular evolutionary analyses. VESPA provides flexible software for simplifying these processes along with downstream selective pressure variation analyses. The software automatically interprets results from codeML and produces simplified summary files to assist the user in better understanding the results. VESPA may be found at the following website: http://www.mol-evol.org/VESPA.

  13. APT Blanket Safety Analysis: Preliminary Analyses of Downflow Through a Lateral Row 1 Blanket Model Under Near RHR Conditions

    Energy Technology Data Exchange (ETDEWEB)

    Hamm, L.L.

    1998-10-07

    To address a concern about a potential maldistribution of coolant flow through an APT blanket module under low flow near RHR conditions, a scoping study of downflow mixed convection in parallel channels was conducted. Buoyancy will adversely effect the flow distribution in module bins with downflow and non-uniform power distributions. This study consists of two parts: a simple analytical model of flow in a two channel network, and a lumped eleven channel FLOWTRAN-TF model of a front lateral Row-1 blanket module bin. Results from both models indicate that the concern about coolant flow in a vertical model being diverted away from high power regions by buoyancy is warranted. The FLOWTRAN-TF model predicted upflow (i.e., a flow reversal) through several of the high power channels, under some low flow conditions. The transition from the regime with downflow in all channels to a regime with upflow in some channels was abrupt.

  14. 鱼类白化现象病因浅析%PRELIMINARY ANALYSE OF THE PATHOGENY OF ALBINISM IN FISH

    Institute of Scientific and Technical Information of China (English)

    王鑫; 郭恩棉; 苏振渝; 张丽; 付国庆

    2003-01-01

    @@ 鱼类的载色素细胞包括众所周知的、不发光的褐色素细胞、黑色素细胞,红色素细胞、黄色素细胞.而在动物王国最普遍的黑色素的沉着常出现异常现象,这包括色素沉着过度和白化现象.

  15. Positron emission tomography study of pindolol occupancy of 5-HT{sub 1A} receptors in humans: preliminary analyses

    Energy Technology Data Exchange (ETDEWEB)

    Martinez, Diana; Mawlawi, Osama; Hwang, Dah-Ren; Kent, Justine; Simpson, Norman; Parsey, Ramin V.; Hashimoto, Tomoki; Slifstein, Mark; Huang Yiyun; Heertum, Ronald van; Abi-Dargham, Anissa; Caltabiano, Stephen; Malizia, Andrea; Cowley, Hugh; Mann, J. John; Laruelle, Marc

    2000-07-01

    Preclinical studies in rodents suggest that augmentation of serotonin reuptake inhibitors (SSRIs) therapy by the 5-hydroxytryptamine{sub 1A} (5-HT{sub 1A}) receptor agent pindolol might reduce the delay between initiation of treatment and antidepressant response. This hypothesis is based on the ability of pindolol to potentiate the increase in serotonin (5-HT) transmission induced by SSRIs, an effect achieved by blockade of the 5-HT{sub 1A} autoreceptors in the dorsal raphe nuclei (DRN). However, placebo-controlled clinical studies of pindolol augmentation of antidepressant therapy have reported inconsistent results. Here, we evaluated the occupancy of 5-HT{sub 1A} receptors following treatment with controlled release pindolol in nine healthy volunteers with positron-emission tomography (PET). Each subject was studied four times: at baseline (scan 1), following 1 week of oral administration of pindolol CR (7.5 mg/day) at peak level, 4 h after the dose (scan 2), and at 10 h following the dose (scan 3), and following one dose of pindolol CR (30 mg) (at peak level, 4 h) (scan 4). Pindolol occupancy of 5-HT{sub 1A} receptors was evaluated in the DRN and cortical regions as the decrease in binding potential (BP) of the radiolabelled selective 5-HT{sub 1A} antagonist [carbonyl-{sup 11}C]WAY-100635 or [carbonyl-{sup 11}C] N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridyl) cyclohexanecarboxamide abbreviated as [{sup 11}C]WAY-100635. Pindolol dose-dependently decreased [{sup 11}C]WAY-100635 BP. Combining all the regions, occupancy was 20 {+-} 8% at scan 2, 14 {+-} 8% at scan 3, and 44 {+-} 8% at scan 4. The results of this study suggest that at doses used in clinical studies of augmentation of the SSRI effect by pindolol (2.5 mg t.i.d.), the occupancy of 5-HT{sub 1A} receptors is moderate and highly variable between subjects. This factor might explain the variable results obtained in clinical studies. On the other hand, at each dose tested, pindolol occupancy of 5-HT{sub 1A} receptors was higher in the DRN compared to cortical regions, demonstrating a significant in vivo selectivity for DRN 5-HT{sub 1A} autoreceptors relative to cortico-limbic postsynaptic receptors. This selectivity is necessary for the potentiation of 5-HT transmission, and this finding represents an important proof of concept in the development of 5-HT{sub 1A} agents for this application. Early evaluation of new drugs with PET imaging will enable rapid screening of compounds based on DRN selectivity and more appropriate determination of doses for clinical trials.

  16. Early maladaptive schemas in convicted sexual offenders: preliminary findings.

    Science.gov (United States)

    Carvalho, Joana; Nobre, Pedro J

    2014-01-01

    Core cognitive schemas may play a role in the vulnerability for sexual offending. Identifying these schemas could help to conceptualize sexual crimes and rehabilitate convicted sexual offenders. The aim of this preliminary study was to explore the relationship between early maladaptive schemas (EMSs) and sexual offending, as well as how rapists and child sex molesters differ in terms of these schemas. Thirty-two men convicted for rape, 33 convicted for child sexual abuse, and 30 non-offenders were evaluated using the Young Schema Questionnaire (YSQ-S3) and the Brief Symptom Inventory (BSI). Results showed that participants convicted for child sexual abuse presented significantly more schemas from the disconnection/rejection, impaired autonomy/performance, other directness, and over vigilance/inhibition domains than non-offenders, whereas rapists presented more schemas from the impaired autonomy/performance domain than non-offenders. Differences between sex offenders showed that child molesters presented more schemas of pessimism than rapists. Preliminary findings suggested that EMSs may impact sex offender's perceptions about themselves and about the world. Schema-focused therapy (Young, 1990, 1999) may thus be an acceptable approach to sex offender's psychological assessment and intervention.

  17. [The use of nitric oxide during transport of newborns with critical respiratory insufficiency: own experience, preliminary report].

    Science.gov (United States)

    Ziebiński, Marek; Walas, Wojciech

    2002-01-01

    This preliminary report presents author's experience with inhaled nitric oxide during transport of newborns with critical respiratory insufficiency. The theoretical basis, indications and contraindications as well as principles of administration during transport are described. The required equipment and some technical aspects are discussed. A short preview of performed transportations is given. Preliminary data show, that use of NO during transport is very helpful in children with critical respiratory insufficiency.

  18. Iron interference in arsenic absorption by different plant species, analysed by neutron activation, k{sub 0}-method

    Energy Technology Data Exchange (ETDEWEB)

    Uemura, George; Matos, Ludmila Vieira da Silva; Silva, Maria Aparecida da; Menezes, Maria Angela de Barros Correia [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN-CNEN/MG), Belo Horizonte, MG (Brazil)], e-mail: george@cdtn.br, e-mail: menezes@cdtn.br

    2009-07-01

    Natural arsenic contamination is a cause for concern in many countries of the world including Argentina, Bangladesh, Chile, China, India, Mexico, Thailand, United States of America and also in Brazil, specially in the Iron Quadrangle area, where mining activities have been contributing to aggravate natural contamination. Among other elements, iron is capable to interfere with the arsenic absorption by plants; iron ore has been proposed to remediate areas contaminated by the mentioned metalloid. In order to verify if iron can interfere with arsenic absorption by different taxa of plants, specimens of Brassicacea and Equisetaceae were kept in a 1/4 Murashige and Skoog basal salt solution (M and S), with 10 {mu}gL{sup -1} of arsenic acid. And varying concentrations of iron. The specimens were analysed by neutron activation analysis, k{sub 0}-method, a routine technique in CDTN, and also very appropriate for arsenic studies. The preliminary results were quite surprising, showing that iron can interfere with arsenic absorption by plants, but in different ways, according to the species studied. (author)

  19. Joint U.S./Russian Study on the Development of a Preliminary Cost Estimate of the SAFSTOR Decommissioning Alternative for the Leningrad Nuclear Power Plant Unit #1

    Energy Technology Data Exchange (ETDEWEB)

    SM Garrett

    1998-09-28

    The objectives of the two joint Russian/U.S. Leningrad Nuclear Power Plant (NPP) Unit #1 studies were the development of a safe, technically feasible, economically acceptable decom missioning strategy, and the preliminary cost evaluation of the developed strategy. The first study, resulting in the decommissioning strategy, was performed in 1996 and 1997. The preliminary cost estimation study, described in this report, was performed in 1997 and 1998. The decommissioning strategy study included the analyses of three basic RBM.K decommission- ing alternatives, refined for the Leningrad NPP Unit #1. The analyses included analysis of the requirements for the planning and preparation as well as the decommissioning phases.

  20. Development and Verification of Tritium Analyses Code for a Very High Temperature Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Chang H. Oh; Eung S. Kim

    2009-09-01

    A tritium permeation analyses code (TPAC) has been developed by Idaho National Laboratory for the purpose of analyzing tritium distributions in the VHTR systems including integrated hydrogen production systems. A MATLAB SIMULINK software package was used for development of the code. The TPAC is based on the mass balance equations of tritium-containing species and a various form of hydrogen (i.e., HT, H2, HTO, HTSO4, and TI) coupled with a variety of tritium source, sink, and permeation models. In the TPAC, ternary fission and neutron reactions with 6Li, 7Li 10B, 3He were taken into considerations as tritium sources. Purification and leakage models were implemented as main tritium sinks. Permeation of HT and H2 through pipes, vessels, and heat exchangers were importantly considered as main tritium transport paths. In addition, electroyzer and isotope exchange models were developed for analyzing hydrogen production systems including both high-temperature electrolysis and sulfur-iodine process. The TPAC has unlimited flexibility for the system configurations, and provides easy drag-and-drops for making models by adopting a graphical user interface. Verification of the code has been performed by comparisons with the analytical solutions and the experimental data based on the Peach Bottom reactor design. The preliminary results calculated with a former tritium analyses code, THYTAN which was developed in Japan and adopted by Japan Atomic Energy Agency were also compared with the TPAC solutions. This report contains descriptions of the basic tritium pathways, theory, simple user guide, verifications, sensitivity studies, sample cases, and code tutorials. Tritium behaviors in a very high temperature reactor/high temperature steam electrolysis system have been analyzed by the TPAC based on the reference indirect parallel configuration proposed by Oh et al. (2007). This analysis showed that only 0.4% of tritium released from the core is transferred to the product hydrogen

  1. 32 CFR 644.30 - Preliminary real estate work.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Preliminary real estate work. 644.30 Section 644... PROPERTY REAL ESTATE HANDBOOK Project Planning Military (army and Air Force) and Other Federal Agencies § 644.30 Preliminary real estate work. (a) Preliminary real estate work is defined as that action taken...

  2. 29 CFR 1601.23 - Preliminary or temporary relief.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Preliminary or temporary relief. 1601.23 Section 1601.23... Employment Practices § 1601.23 Preliminary or temporary relief. (a) In the interest of the expeditious... subdivision, any recommendation for preliminary or temporary relief shall be transmitted directly to the...

  3. Fungal communities in wheat grain show significant co-existence patterns among species

    DEFF Research Database (Denmark)

    Nicolaisen, M.; Justesen, A. F.; Knorr, K.;

    2014-01-01

    identified as ‘core’ OTUs as they were found in all or almost all samples and accounted for almost 99 % of all sequences. The remaining OTUs were only sporadically found and only in small amounts. Cluster and factor analyses showed patterns of co-existence among the core species. Cluster analysis grouped...

  4. Crystallization and preliminary X-ray structural studies of a Melan-A pMHC–TCR complex

    Energy Technology Data Exchange (ETDEWEB)

    Yuan, Fang [Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford University, Oxford OX3 9DU (United Kingdom); Georgiou, Theonie; Hillon, Theresa [STFC Daresbury Laboratory, Warrington, Cheshire WA4 4AD (United Kingdom); Gostick, Emma; Price, David A. [Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford University, Oxford OX3 9DU (United Kingdom); Sewell, Andrew K. [Medical Biochemistry and Immunology, Cardiff University School of Medicine, Cardiff CF14 4XN,Wales (United Kingdom); Moysey, Ruth; Gavarret, Jessie; Vuidepot, Annelise; Sami, Malkit [Medigene, 57c Milton Park, Abingdon, Oxdfordshire OX14 4RX (United Kingdom); Bell, John I. [Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford University, Oxford OX3 9DU (United Kingdom); Gao, George F. [Center for Molecular Immunology, Institute of Microbiology, Chinese Academy of Sciences, 13 Beiyitiao, Zhongguancun, Beijing 100080 (China); Rizkallah, Pierre J., E-mail: p.j.rizkallah@dl.ac.uk [STFC Daresbury Laboratory, Warrington, Cheshire WA4 4AD (United Kingdom); Jakobsen, Bent K., E-mail: p.j.rizkallah@dl.ac.uk [Medigene, 57c Milton Park, Abingdon, Oxdfordshire OX14 4RX (United Kingdom); Nuffield Department of Clinical Medicine, John Radcliffe Hospital, Oxford University, Oxford OX3 9DU (United Kingdom)

    2007-09-01

    A preliminary X-ray crystal structural study of a soluble cognate T-cell receptor (TCR) in complex with a pMHC presenting the Melan-A peptide (ELAGIGILTV) is reported. The TCR and pMHC were refolded, purified and mixed together to form complexes, which were crystallized using the sitting-drop vapour-diffusion method. Single TCR–pMHC complex crystals were cryocooled and used for data collection. Melanocytes are specialized pigmented cells that are found in all healthy skin tissue. In certain individuals, diseased melanocytes can form malignant tumours, melanomas, which cause the majority of skin-cancer-related deaths. The melanoma-associated antigenic peptides are presented on cell surfaces via the class I major histocompatibility complex (MHC). Among the melanoma-associated antigens, the melanoma self-antigen A/melanoma antigen recognized by T cells (Melan-A/MART-1) has attracted attention because of its wide expression in primary and metastatic melanomas. Here, a preliminary X-ray crystal structural study of a soluble cognate T-cell receptor (TCR) in complex with a pMHC presenting the Melan-A peptide (ELAGIGILTV) is reported. The TCR and pMHC were refolded, purified and mixed together to form complexes, which were crystallized using the sitting-drop vapour-diffusion method. Single TCR–pMHC complex crystals were cryocooled and used for data collection. Diffraction data showed that these crystals belonged to space group P4{sub 1}/P4{sub 3}, with unit-cell parameters a = b = 120.4, c = 81.6 Å. A complete data set was collected to 3.1 Å and the structure is currently being analysed.

  5. Random error in cardiovascular meta-analyses

    DEFF Research Database (Denmark)

    Albalawi, Zaina; McAlister, Finlay A; Thorlund, Kristian;

    2013-01-01

    BACKGROUND: Cochrane reviews are viewed as the gold standard in meta-analyses given their efforts to identify and limit systematic error which could cause spurious conclusions. The potential for random error to cause spurious conclusions in meta-analyses is less well appreciated. METHODS: We...... examined all reviews approved and published by the Cochrane Heart Group in the 2012 Cochrane Library that included at least one meta-analysis with 5 or more randomized trials. We used trial sequential analysis to classify statistically significant meta-analyses as true positives if their pooled sample size...... but infrequently recognized, even among methodologically robust reviews published by the Cochrane Heart Group. Meta-analysts and readers should incorporate trial sequential analysis when interpreting results....

  6. Genome-Facilitated Analyses of Geomicrobial Processes

    Energy Technology Data Exchange (ETDEWEB)

    Kenneth H. Nealson

    2012-05-02

    This project had the goal(s) of understanding the mechanism(s) of extracellular electron transport (EET) in the microbe Shewanella oneidensis MR-1, and a number of other strains and species in the genus Shewanella. The major accomplishments included sequencing, annotation, and analysis of more than 20 Shewanella genomes. The comparative genomics enabled the beginning of a systems biology approach to this genus. Another major contribution involved the study of gene regulation, primarily in the model organism, MR-1. As part of this work, we took advantage of special facilities at the DOE: e.g., the synchrotron radiation facility at ANL, where we successfully used this system for elemental characterization of single cells in different metabolic states (1). We began work with purified enzymes, and identification of partially purified enzymes, leading to initial characterization of several of the 42 c-type cytochromes from MR-1 (2). As the genome became annotated, we began experiments on transcriptome analysis under different conditions of growth, the first step towards systems biology (3,4). Conductive appendages of Shewanella, called bacterial nanowires were identified and characterized during this work (5, 11, 20,21). For the first time, it was possible to measure the electron transfer rate between single cells and a solid substrate (20), a rate that has been confirmed by several other laboratories. We also showed that MR-1 cells preferentially attach to cells at a given charge, and are not attracted, or even repelled by other charges. The interaction with the charged surfaces begins with a stimulation of motility (called electrokinesis), and eventually leads to attachment and growth. One of the things that genomics allows is the comparative analysis of the various Shewanella strains, which led to several important insights. First, while the genomes predicted that none of the strains looked like they should be able to degrade N-acetyl glucosamine (NAG), the monomer

  7. Eksakte metodar for analyse av tovegstabellar

    OpenAIRE

    Aaberge, Rolf

    1980-01-01

    Dei fleste matematisk-statistiske metodane som er utvikla til analyse av tabellar, byggjer på føresetnader om at talet på observasjonar i tabellcellene er "stort. Haldorsen (1977a) og (1977b) omtalar metodar som kviler på dette kravet. I denne rapporten skal vi presentere eksakte metodar for analyse av to-vegstabel lar, dvs. metodar som er gyldige sjølv om vi har småe observasjonstal i tabellcellene. I mange undersøkingar vil observasjonane ofte gi uttrykk for kva slags ...

  8. A theoretical framework for analysing preschool teaching

    DEFF Research Database (Denmark)

    Chaiklin, Seth

    2014-01-01

    This article introduces a theoretical framework for analysing preschool teaching as a historically-grounded societal practice. The aim is to present a unified framework that can be used to analyse and compare both historical and contemporary examples of preschool teaching practice within and across...... national traditions. The framework has two main components, an analysis of preschool teaching as a practice, formed in relation to societal needs, and an analysis of the categorical relations which necessarily must be addressed in preschool teaching activity. The framework is introduced and illustrated...

  9. The application analyses for primary spectrum pyrometer

    Institute of Scientific and Technical Information of China (English)

    FU; TaiRan

    2007-01-01

    In the applications of primary spectrum pyrometry, based on the dynamic range and the minimum sensibility of the sensor, the application issues, such as the measurement range and the measurement partition, were investigated through theoretical analyses. For a developed primary spectrum pyrometer, the theoretical predictions of measurement range and the distributions of measurement partition were presented through numerical simulations. And the measurement experiments of high-temperature blackbody and standard temperature lamp were processed to further verify the above theoretical analyses and numerical results. Therefore the research in the paper provides the helpful supports for the applications of primary spectrum pyrometer and other radiation pyrometers.……

  10. Identifying, analysing and solving problems in practice.

    Science.gov (United States)

    Hewitt-Taylor, Jaqui

    When a problem is identified in practice, it is important to clarify exactly what it is and establish the cause before seeking a solution. This solution-seeking process should include input from those directly involved in the problematic situation, to enable individuals to contribute their perspective, appreciate why any change in practice is necessary and what will be achieved by the change. This article describes some approaches to identifying and analysing problems in practice so that effective solutions can be devised. It includes a case study and examples of how the Five Whys analysis, fishbone diagram, problem tree analysis, and Seven-S Model can be used to analyse a problem.

  11. Analyses of hydraulic performance of velocity caps

    DEFF Research Database (Denmark)

    Christensen, Erik Damgaard; Degn Eskesen, Mark Chr.; Buhrkall, Jeppe

    2014-01-01

    The hydraulic performance of a velocity cap has been investigated. Velocity caps are often used in connection with offshore intakes. CFD (computational fluid dynamics) examined the flow through the cap openings and further down into the intake pipes. This was combined with dimension analyses...... in order to analyse the effect of different layouts on the flow characteristics. In particular, flow configurations going all the way through the structure were revealed. A couple of suggestions to minimize the risk for flow through have been tested....

  12. Sand laser-ablation as source of elements laser isotope separation: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Rodrigues, N.A.S.; Destro, M.G.; Vasconcelos, G; Neri, J.W.; Silveira, C.A.B.; Riva, R. [Institute for Advanced Studies, Sao Jose dos Campos, SP (Brazil)]. E-mail: nicolau@ieav.cta.br

    2008-07-01

    This paper presents preliminary results of emission spectroscopy experiments, performed with the aim to verify the presence of monoatomic neutral material in the jet produced by laser ablation of simple and complex targets. All studied materials (copper, graphite, alumina and beach sand) showed emission of single atoms, indicating the presence of monoatomic material in the ablated plume. (author)

  13. Nevada potential repository preliminary transportation strategy Study 2. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-01

    The objectives of this study were to build on the findings of the Nevada Potential Repository Preliminary Transportation Strategy Study 1 (CRWMS M&O 1995b), and to provide additional information for input to the repository environmental impact statement (EIS) process. In addition, this study supported the future selection of a preferred rail corridor and/or heavy haul route based on defensible data, methods, and analyses. Study research did not consider proposed legislation. Planning was conducted according to the Civilian Radioactive Waste Management Program Plan (DOE 1994a). The specific objectives of Study 2 were to: eliminate or reduce data gaps, inconsistencies, and uncertainties, and strengthen the analysis performed in Study 1; develop a preliminary list of rail route evaluation criteria that could be used to solicit input from stakeholders during scoping meetings. The evaluation criteria will be revised based on comments received during scoping; restrict and refine the width of the four rail corridors identified in Study 1 to five miles or less, based on land use constraints and engineering criteria identified and established in Study 2; evaluate national-level effects of routing spent nuclear fuel and high-level waste to the four identified branch lines, including the effects of routing through or avoiding Las Vegas; continue to gather published land use information and environmental data to support the repository EIS; continue to evaluate heavy haul truck transport over three existing routes as an alternative to rail and provide sufficient information to support the repository EIS process; and evaluate secondary uses for rail (passenger use, repository construction, shared use).

  14. Environmental Survey preliminary report, Pinellas Plant, Largo, Florida

    Energy Technology Data Exchange (ETDEWEB)

    1987-11-01

    The purpose of this report is to present the preliminary findings made during the Environmental Survey, conducted May 11 through 22, 1987, at the United States Department of Energy (DOE) Pinellas Plant in Largo, Florida. As a Preliminary Report, the contents are subject to revisions, which will be made in a forthcoming Interim Report, based on Albuquerque Operations Office review and comments on technical accuracy, the results of the sampling and analyses, and other information that may come to the Survey team's attention prior to issuance of the Interim Report. The Pinellas Plant is currently operated for DOE by the General Electric Company-Neutron Devices Department (GENDD). The Pinellas Survey is part of the larger DOE-wide Environmental Survey effort announced by Secretary John S. Herrington on September 18, 1985. The purpose of this effort is to identify, via no fault'' baseline Surveys, existing environmental problems are areas of environmental risk at DOE facilities and to rank them on a DOE-wide basis. This ranking will enable DOE to more effectively establish priorities for addressing environmental problems and allocate the resources necessary to correct these problems. Because the Survey is no fault'' and is not an audit,'' it is not designed to identify specific isolated incidents of noncompliance or to analyze environmental management practices. Such incidents and/or management practices will, however, be used in the Survey as a means of identifying existing and potential environmental problems. 55 refs., 37 figs., 37 tabs.

  15. Preliminary phytochemical screening, pharmacognostic and physicochemical evalution of leaf of Gmelina arborea

    Institute of Scientific and Technical Information of China (English)

    Daya L Chothani; N M Patel

    2012-01-01

    Objective: The aim of present study was to carry out preliminary phytochemical screening, detailed pharmacognostic profile and physicochemical evaluation of leaf of Gmelina arborea. Methods: Fresh leaf and dried power of the leaves were studied by morphology, microscopy, preliminary phytochemical screening, and florescence analysis of powdered drug. Other physicochemical parameters were also performed as per WHO guide lines. Result: The detailed microscopy revealed that the presence of anomocytic stomata and covering uni-multicellular trichome. Leaf constant such as stomatal number, stomata index, vein islet number, vein termination number were also determined. Physicochemical parameters and florescence analysis were also studied. The preliminary phytochemical screening showed the presence of steroid, triterpenoid, saponin, protein, phenolic compound, flavanoid and carbohydrates. Conclusions:The result of these studies could be useful for correct identification and detection of adulterants of this plant material.

  16. Preliminary results from the {sup 51}Cr neutrino source experiment in GALLEX

    Energy Technology Data Exchange (ETDEWEB)

    Hampel, W.; Heusser, G.; Kiko, J. [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany)] [and others

    1996-09-01

    The GALLEX collaboration performed a second {sup 51}Cr neutrino source experiment during fall 1995. The full results from this second source experiment will not be available before the end of 1996. Meanwhile, we present a short description and preliminary results in this informal note. The (preliminary) value of the activity obtained form direct measurements has been found equal to (68.7 {+-}0.7) PBq (with 1-sigma error). This value, which is about 10% higher than the activity of the first source, was achieved by optimizing the irradiation conditions in the Silo{acute e} reactor and doing a longer irradiation of the enriched chromium. Preliminary results show that the ratio, R, of the radiochemically determined activity from {sup 71}Ge counting (57.1 {+-} PBq) to the directly measured activity is (0.83 {+-} 0.10). The combined value of R for the two source experiments is (0.92 {+-} 0.08).

  17. 32 CFR 552.78 - “Show cause” hearing.

    Science.gov (United States)

    2010-07-01

    ....78 “Show cause” hearing. Before suspending the solicitation privilege, the company and the agent will have a chance to show cause why the action should not be taken. “Show cause” is an opportunity for...

  18. Food Safety Not Always on Menu of TV Cooking Shows

    Science.gov (United States)

    ... page: https://medlineplus.gov/news/fullstory_161980.html Food Safety Not Always on Menu of TV Cooking Shows ... shows. They also noted whether the shows mentioned food safety. The findings were published in the November-December ...

  19. Preliminary investigation of self-as-context in people with fibromyalgia.

    Science.gov (United States)

    Yu, Lin; Norton, Sam; Almarzooqi, Sarah; McCracken, Lance M

    2017-08-01

    Acceptance and commitment therapy (ACT), based on the Psychological Flexibility (PF) model, has been recently applied to fibromyalgia (FM), and appeared effective in improving functioning. However, evidence for some of the processes within the PF model, self-as-context (SAC) in particular, is lacking within this population. The current study validates a measure of SAC, the Self Experiences Questionnaire (SEQ), and preliminarily investigates the role of SAC in relation to functioning in FM. Participants (N = 298, 93.3% women) self-reporting a diagnosis of FM were recruited via the Internet and completed an online survey. Measures included pain, pain acceptance and SAC, as processes, and pain interference, work and social adjustment, depression and depression-related interference, as outcomes. Confirmatory factor analysis of the SEQ suggested a bi-factor structure, with a general factor underlying all items and two sub-factors, self-as-distinction and self-as-observer (χ2 = 46.55, p = .06, comparative fit index (CFI) = .99, Tucker-Lewis Index (TLI) = .99, root mean square error of approximation (RMSEA) = .04). Component factors showed good reliability, Cronbach's α = .90, and construct validity, supported by significant Pearson's correlations between SEQ scores, acceptance and outcomes (r = -.14 to -.33). In multiple regression analyses, SEQ scores significantly predicted pain-related interference (β = -.17, p < .05), work and social adjustment (β = -.14, p < .05) and depression (β = -.21, p < .01), but not depression-related interference, after controlling for pain, but only significantly predicted depression after controlling pain acceptance. These preliminary results show potentially important associations between SAC and functioning in people with FM.

  20. Runtime and Pressurization Analyses of Propellant Tanks

    Science.gov (United States)

    Field, Robert E.; Ryan, Harry M.; Ahuja, Vineet; Hosangadi, Ashvin; Lee, Chung P.

    2007-01-01

    Multi-element unstructured CFD has been utilized at NASA SSC to carry out analyses of propellant tank systems in different modes of operation. The three regimes of interest at SSC include (a) tank chill down (b) tank pressurization and (c) runtime propellant draw-down and purge. While tank chill down is an important event that is best addressed with long time-scale heat transfer calculations, CFD can play a critical role in the tank pressurization and runtime modes of operation. In these situations, problems with contamination of the propellant by inclusion of the pressurant gas from the ullage causes a deterioration of the quality of the propellant delivered to the test article. CFD can be used to help quantify the mixing and propellant degradation. During tank pressurization under some circumstances, rapid mixing of relatively warm pressurant gas with cryogenic propellant can lead to rapid densification of the gas and loss of pressure in the tank. This phenomenon can cause serious problems during testing because of the resulting decrease in propellant flow rate. With proper physical models implemented, CFD can model the coupling between the propellant and pressurant including heat transfer and phase change effects and accurately capture the complex physics in the evolving flowfields. This holds the promise of allowing the specification of operational conditions and procedures that could minimize the undesirable mixing and heat transfer inherent in propellant tank operation. It should be noted that traditional CFD modeling is inadequate for such simulations because the fluids in the tank are in a range of different sub-critical and supercritical states and elaborate phase change and mixing rules have to be developed to accurately model the interaction between the ullage gas and the propellant. We show a typical run-time simulation of a spherical propellant tank, containing RP-1 in this case, being pressurized with room-temperature nitrogen at 540 R. Nitrogen

  1. Uncertainty quantification approaches for advanced reactor analyses.

    Energy Technology Data Exchange (ETDEWEB)

    Briggs, L. L.; Nuclear Engineering Division

    2009-03-24

    The original approach to nuclear reactor design or safety analyses was to make very conservative modeling assumptions so as to ensure meeting the required safety margins. Traditional regulation, as established by the U. S. Nuclear Regulatory Commission required conservatisms which have subsequently been shown to be excessive. The commission has therefore moved away from excessively conservative evaluations and has determined best-estimate calculations to be an acceptable alternative to conservative models, provided the best-estimate results are accompanied by an uncertainty evaluation which can demonstrate that, when a set of analysis cases which statistically account for uncertainties of all types are generated, there is a 95% probability that at least 95% of the cases meet the safety margins. To date, nearly all published work addressing uncertainty evaluations of nuclear power plant calculations has focused on light water reactors and on large-break loss-of-coolant accident (LBLOCA) analyses. However, there is nothing in the uncertainty evaluation methodologies that is limited to a specific type of reactor or to specific types of plant scenarios. These same methodologies can be equally well applied to analyses for high-temperature gas-cooled reactors and to liquid metal reactors, and they can be applied to steady-state calculations, operational transients, or severe accident scenarios. This report reviews and compares both statistical and deterministic uncertainty evaluation approaches. Recommendations are given for selection of an uncertainty methodology and for considerations to be factored into the process of evaluating uncertainties for advanced reactor best-estimate analyses.

  2. Integrated genomic analyses of ovarian carcinoma

    NARCIS (Netherlands)

    Bell, D.; Berchuck, A.; Birrer, M.; Chien, J.; Dao, F.; Dhir, R.; DiSaia, P.; Gabra, H.; Glenn, P.; Godwin, A. K.; Gross, J.; Hartmann, L.; Huang, M.; Huntsman, D. G.; Iacocca, M.; Imielinski, M.; Kalloger, S.; Karlan, B. Y.; Levine, D. A.; Mills, G. B.; Morrison, C.; Mutch, D.; Olvera, N.; Orsulic, S.; Park, K.; Petrelli, N.; Rabeno, B.; Rader, J. S.; Sikic, B. I.; Smith-McCune, K.; Sood, A. K.; Bowtell, D.; Penny, R.; Testa, J. R.; Chang, K.; Dinh, H. H.; Drummond, J. A.; Fowler, G.; Gunaratne, P.; Hawes, A. C.; Kovar, C. L.; Lewis, L. R.; Morgan, M. B.; Newsham, I. F.; Santibanez, J.; Reid, J. G.; Trevino, L. R.; Wu, Y. -Q.; Wang, M.; Muzny, D. M.; Wheeler, D. A.; Gibbs, R. A.; Getz, G.; Lawrence, M. S.; Cibulskis, K.; Sivachenko, A. Y.; Sougnez, C.; Voet, D.; Wilkinson, J.; Bloom, T.; Ardlie, K.; Fennell, T.; Baldwin, J.; Gabriel, S.; Lander, E. S.; Ding, L.; Fulton, R. S.; Koboldt, D. C.; McLellan, M. D.; Wylie, T.; Walker, J.; O'Laughlin, M.; Dooling, D. J.; Fulton, L.; Abbott, R.; Dees, N. D.; Zhang, Q.; Kandoth, C.; Wendl, M.; Schierding, W.; Shen, D.; Harris, C. C.; Schmidt, H.; Kalicki, J.; Delehaunty, K. D.; Fronick, C. C.; Demeter, R.; Cook, L.; Wallis, J. W.; Lin, L.; Magrini, V. J.; Hodges, J. S.; Eldred, J. M.; Smith, S. M.; Pohl, C. S.; Vandin, F.; Raphael, B. J.; Weinstock, G. M.; Mardis, R.; Wilson, R. K.; Meyerson, M.; Winckler, W.; Getz, G.; Verhaak, R. G. W.; Carter, S. L.; Mermel, C. H.; Saksena, G.; Nguyen, H.; Onofrio, R. C.; Lawrence, M. S.; Hubbard, D.; Gupta, S.; Crenshaw, A.; Ramos, A. H.; Ardlie, K.; Chin, L.; Protopopov, A.; Zhang, Juinhua; Kim, T. M.; Perna, I.; Xiao, Y.; Zhang, H.; Ren, G.; Sathiamoorthy, N.; Park, R. W.; Lee, E.; Park, P. J.; Kucherlapati, R.; Absher, D. M.; Waite, L.; Sherlock, G.; Brooks, J. D.; Li, J. Z.; Xu, J.; Myers, R. M.; Laird, P. W.; Cope, L.; Herman, J. G.; Shen, H.; Weisenberger, D. J.; Noushmehr, H.; Pan, F.; Triche, T.; Berman, B. P.; Van den Berg, D. J.; Buckley, J.; Baylin, S. B.; Spellman, P. T.; Purdom, E.; Neuvial, P.; Bengtsson, H.; Jakkula, L. R.; Durinck, S.; Han, J.; Dorton, S.; Marr, H.; Choi, Y. G.; Wang, V.; Wang, N. J.; Ngai, J.; Conboy, J. G.; Parvin, B.; Feiler, H. S.; Speed, T. P.; Gray, J. W.; Levine, D. A.; Socci, N. D.; Liang, Y.; Taylor, B. S.; Schultz, N.; Borsu, L.; Lash, A. E.; Brennan, C.; Viale, A.; Sander, C.; Ladanyi, M.; Hoadley, K. A.; Meng, S.; Du, Y.; Shi, Y.; Li, L.; Turman, Y. J.; Zang, D.; Helms, E. B.; Balu, S.; Zhou, X.; Wu, J.; Topal, M. D.; Hayes, D. N.; Perou, C. M.; Getz, G.; Voet, D.; Saksena, G.; Zhang, Junihua; Zhang, H.; Wu, C. J.; Shukla, S.; Cibulskis, K.; Lawrence, M. S.; Sivachenko, A.; Jing, R.; Park, R. W.; Liu, Y.; Park, P. J.; Noble, M.; Chin, L.; Carter, H.; Kim, D.; Karchin, R.; Spellman, P. T.; Purdom, E.; Neuvial, P.; Bengtsson, H.; Durinck, S.; Han, J.; Korkola, J. E.; Heiser, L. M.; Cho, R. J.; Hu, Z.; Parvin, B.; Speed, T. P.; Gray, J. W.; Schultz, N.; Cerami, E.; Taylor, B. S.; Olshen, A.; Reva, B.; Antipin, Y.; Shen, R.; Mankoo, P.; Sheridan, R.; Ciriello, G.; Chang, W. K.; Bernanke, J. A.; Borsu, L.; Levine, D. A.; Ladanyi, M.; Sander, C.; Haussler, D.; Benz, C. C.; Stuart, J. M.; Benz, S. C.; Sanborn, J. Z.; Vaske, C. J.; Zhu, J.; Szeto, C.; Scott, G. K.; Yau, C.; Hoadley, K. A.; Du, Y.; Balu, S.; Hayes, D. N.; Perou, C. M.; Wilkerson, M. D.; Zhang, N.; Akbani, R.; Baggerly, K. A.; Yung, W. K.; Mills, G. B.; Weinstein, J. N.; Penny, R.; Shelton, T.; Grimm, D.; Hatfield, M.; Morris, S.; Yena, P.; Rhodes, P.; Sherman, M.; Paulauskis, J.; Millis, S.; Kahn, A.; Greene, J. M.; Sfeir, R.; Jensen, M. A.; Chen, J.; Whitmore, J.; Alonso, S.; Jordan, J.; Chu, A.; Zhang, Jinghui; Barker, A.; Compton, C.; Eley, G.; Ferguson, M.; Fielding, P.; Gerhard, D. S.; Myles, R.; Schaefer, C.; Shaw, K. R. Mills; Vaught, J.; Vockley, J. B.; Good, P. J.; Guyer, M. S.; Ozenberger, B.; Peterson, J.; Thomson, E.; Cramer, D.W.

    2011-01-01

    A catalogue of molecular aberrations that cause ovarian cancer is critical for developing and deploying therapies that will improve patients' lives. The Cancer Genome Atlas project has analysed messenger RNA expression, microRNA expression, promoter methylation and DNA copy number in 489 high-grade

  3. Challenges and Opportunities in Analysing Students Modelling

    Science.gov (United States)

    Blanco-Anaya, Paloma; Justi, Rosária; Díaz de Bustamante, Joaquín

    2017-01-01

    Modelling-based teaching activities have been designed and analysed from distinct theoretical perspectives. In this paper, we use one of them--the model of modelling diagram (MMD)--as an analytical tool in a regular classroom context. This paper examines the challenges that arise when the MMD is used as an analytical tool to characterise the…

  4. Chemical analyses, antibacterial activity and genetic diversity ...

    African Journals Online (AJOL)

    SAM

    2014-06-25

    Jun 25, 2014 ... Key words: Citrus, genetic diversity, ISSR markers, chemical analyses, antibacterial. ... ment of DNA based marker systems has advanced our ... Total acidity of the juices was determined by titration method as ... Greek compressed C. sinensis. 37 163 ..... flavonoids have a large spectrum of biological activity.

  5. Comparison of veterinary import risk analyses studies

    NARCIS (Netherlands)

    Vos-de Jong, de C.J.; Conraths, F.J.; Adkin, A.; Jones, E.M.; Hallgren, G.S.; Paisley, L.G.

    2011-01-01

    Twenty-two veterinary import risk analyses (IRAs) were audited: a) for inclusion of the main elements of risk analysis; b) between different types of IRAs; c) between reviewers' scores. No significant differences were detected between different types of IRAs, although quantitative IRAs and IRAs publ

  6. Cosmetology: Task Analyses. Competency-Based Education.

    Science.gov (United States)

    Henrico County Public Schools, Glen Allen, VA. Virginia Vocational Curriculum Center.

    These task analyses are designed to be used in combination with the "Trade and Industrial Education Service Area Resource" in order to implement competency-based education in the cosmetology program in Virginia. The task analysis document contains the task inventory, suggested task sequence lists, and content outlines for the secondary…

  7. Meta-analyses on viral hepatitis

    DEFF Research Database (Denmark)

    Gluud, Lise L; Gluud, Christian

    2009-01-01

    This article summarizes the meta-analyses of interventions for viral hepatitis A, B, and C. Some of the interventions assessed are described in small trials with unclear bias control. Other interventions are supported by large, high-quality trials. Although attempts have been made to adjust...

  8. Control of optics in random access analysers

    OpenAIRE

    Truchaud, A.

    1988-01-01

    The technology behind random access analysers involves flexible optical systems which can measure absorbances for one reaction at different scheduled times, and for several reactions performed simultaneously at different wavelengths. Optics control involves light sources (continuous and flash mode), indexing of monochromatic filters, injection-moulded plastic cuvettes, optical fibres, and polychromatic analysis.

  9. The Economic Cost of Homosexuality: Multilevel Analyses

    Science.gov (United States)

    Baumle, Amanda K.; Poston, Dudley, Jr.

    2011-01-01

    This article builds on earlier studies that have examined "the economic cost of homosexuality," by using data from the 2000 U.S. Census and by employing multilevel analyses. Our findings indicate that partnered gay men experience a 12.5 percent earnings penalty compared to married heterosexual men, and a statistically insignificant earnings…

  10. What's missing from avian global diversification analyses?

    Science.gov (United States)

    Reddy, Sushma

    2014-08-01

    The accumulation of vast numbers of molecular phylogenetic studies has contributed to huge knowledge gains in the evolutionary history of birds. This permits subsequent analyses of avian diversity, such as how and why diversification varies across the globe and among taxonomic groups. However, available genetic data for these meta-analyses are unevenly distributed across different geographic regions and taxonomic groups. To comprehend the impact of this variation on the interpretation of global diversity patterns, I examined the availability of genetic data for possible biases in geographic and taxonomic sampling of birds. I identified three main disparities of sampling that are geographically associated with latitude (temperate, tropical), hemispheres (East, West), and range size. Tropical regions, which host the vast majority of species, are substantially less studied. Moreover, Eastern regions, such as the Old World Tropics and Australasia, stand out as being disproportionately undersampled, with up to half of communities not being represented in recent studies. In terms of taxonomic discrepancies, a majority of genetically undersampled clades are exclusively found in tropical regions. My analysis identifies several disparities in the key regions of interest of global diversity analyses. Differential sampling can have considerable impacts on these global comparisons and call into question recent interpretations of latitudinal or hemispheric differences of diversification rates. Moreover, this review pinpoints understudied regions whose biota are in critical need of modern systematic analyses.

  11. Antigen/Antibody Analyses in Leishmaniasis.

    Science.gov (United States)

    1983-09-01

    antibodies in human sera with antigens of protozoan parasites . It was found that enzyme substrate reactions had distinct advantages over typical...autoradiographic procedures. Analyses of various sera identified a number of antigens of protozoan parasites which may be useful in discriminating infections

  12. Microstructure Analyses of NA-Nanodiamond Particles

    Science.gov (United States)

    2016-08-01

    Microscopy Results and Discussion 1 Scanning Electron Microscope (SEM) Analysis 5 Objective 5 Experimental Procedure 5 Discussion of Results 5...420 electron microscope at 120 KV voltage was used for TEM analyses. Transmission Electronic Microscopy Results and Discussion An electron ...SCANNING ELECTRON MICROSCOPE (SEM) ANALYSIS Objective Examine the morphology and elemental chemistry of detonated nanodiamonds (DND

  13. En kvantitativ metode til analyse af radio

    Directory of Open Access Journals (Sweden)

    Christine Lejre

    2014-06-01

    Full Text Available I den danske såvel som den internationale radiolitteratur er bud på metoder til analyse af radiomediet sparsomme. Det skyldes formentlig, at radiomediet er svært at analysere, fordi det er et medie, der ikke er visualiseret i form af billeder eller understøttet af printet tekst. Denne artikel har til formål at beskrive en ny kvantitativ metode til analyse af radio, der tager særligt hensyn til radiomediets modalitet – lyd struktureret som et lineært forløb i tid. Metoden understøtter dermed både radiomediet som et medie i tid og som et blindt medie. Metoden er udviklet i forbindelse med en komparativ analyse af kulturprogrammer på P1 og Radio24syv lavet for Danmarks Radio. Artiklen peger på, at metoden er velegnet til analyse af ikke kun radio, men også andre medieplatforme samt forskellige journalistiske stofområder.

  14. Chemical Analyses of Silicon Aerogel Samples

    CERN Document Server

    van der Werf, I; De Leo, R; Marrone, S

    2008-01-01

    After five years of operating, two Aerogel counters: A1 and A2, taking data in Hall A at Jefferson Lab, suffered a loss of performance. In this note possible causes of degradation have been studied. In particular, various chemical and physical analyses have been carried out on several Aerogel tiles and on adhesive tape in order to reveal the presence of contaminants.

  15. Metodekombination med kritisk analyse

    DEFF Research Database (Denmark)

    Bilfeldt, Annette

    2007-01-01

    "Metodekombination med kritisk teoretisk analyse" fremlægger en kombinationsmetode, der bygges op om en problemstilling med et normativt grundlag for studiet af køn og arbejdsliv. Med fokus på rationalitet og humaniseringsbarrierer i arbejdslivet lægges der med inspiration fra Marie Jahoda op til...

  16. Chemical Analyses of Silicon Aerogel Samples

    Energy Technology Data Exchange (ETDEWEB)

    van der Werf, I.; Palmisano, F.; De Leo, Raffaele; Marrone, Stefano

    2008-04-01

    After five years of operating, two Aerogel counters: A1 and A2, taking data in Hall A at Jefferson Lab, suffered a loss of performance. In this note possible causes of degradation have been studied. In particular, various chemical and physical analyses have been carried out on several Aerogel tiles and on adhesive tape in order to reveal the presence of contaminants.

  17. Analysing spatially extended high-dimensional dynamics by recurrence plots

    Energy Technology Data Exchange (ETDEWEB)

    Marwan, Norbert, E-mail: marwan@pik-potsdam.de [Potsdam Institute for Climate Impact Research, 14412 Potsdam (Germany); Kurths, Jürgen [Potsdam Institute for Climate Impact Research, 14412 Potsdam (Germany); Humboldt Universität zu Berlin, Institut für Physik (Germany); Nizhny Novgorod State University, Department of Control Theory, Nizhny Novgorod (Russian Federation); Foerster, Saskia [GFZ German Research Centre for Geosciences, Section 1.4 Remote Sensing, Telegrafenberg, 14473 Potsdam (Germany)

    2015-05-08

    Recurrence plot based measures of complexity are capable tools for characterizing complex dynamics. In this letter we show the potential of selected recurrence plot measures for the investigation of even high-dimensional dynamics. We apply this method on spatially extended chaos, such as derived from the Lorenz96 model and show that the recurrence plot based measures can qualitatively characterize typical dynamical properties such as chaotic or periodic dynamics. Moreover, we demonstrate its power by analysing satellite image time series of vegetation cover with contrasting dynamics as a spatially extended and potentially high-dimensional example from the real world. - Highlights: • We use recurrence plots for analysing partially extended dynamics. • We investigate the high-dimensional chaos of the Lorenz96 model. • The approach distinguishes different spatio-temporal dynamics. • We use the method for studying vegetation cover time series.

  18. Preliminary environmental analysis of a geopressured-geothermal test well in Brazoria County, Texas

    Energy Technology Data Exchange (ETDEWEB)

    White, W.A.; McGraw, M.; Gustavson, T.C.; Meriwether, J.

    1977-11-16

    Preliminary environmental data, including current land use, substrate lithology, soils, natural hazards, water resources, biological assemblages, meteorological data, and regulatory considerations have been collected and analyzed for approximately 150 km/sup 2/ of land near Chocolate Bayou, Brazoria County, Texas, in which a geopressured-geothermal test well is to be drilled in the fall of 1977. The study was designed to establish an environmental data base and to determine, within spatial constraints set by subsurface reservoir conditions, environmentally suitable sites for the proposed well. Preliminary analyses of data revealed the eed for focusing on the following areas: potential for subsidence and fault activation, susceptibility of test well and support facilities to fresh- and salt-water flooding, possible effects of produced saline waters on biological assemblages and groundwaer resources, distribution of expansive soils, and effect of drilling and associated support activities on known archeological-cultural resources.

  19. Preliminary result of a three dimensional numerical simulation of cloud formation over a cooling pond

    Energy Technology Data Exchange (ETDEWEB)

    Yamada, T.

    1978-01-01

    Cooling ponds receive large amounts of waste heat from industrial sources and release the heat to the atmosphere. These large area sources of warm and moist air may have significant inadvertent effects. This paper is a preliminary step in the development of a method for estimating the perturbations in the atmosphere produced by a cooling pond. A three-dimensional numerical model based on turbulence second-moment closure equations and Gaussian cloud relations has been developed. A simplified version of the model, in which only turbulent energy and length-scale equations are solved prognostically, is used. Numerical simulations are conducted using as boundary conditions the data from a cooling pond study conducted in northern Illinois during the winter of 1976-1977. Preliminary analyses of these simulations indicate that formation of clouds over a cooling pond is sensitive to the moisture content in the ambient atmosphere.

  20. RHF RELAP5 model and preliminary loss-of-offsite-power simulation results for LEU conversion

    Energy Technology Data Exchange (ETDEWEB)

    Licht, J. R. [Argonne National Laboratory (ANL), Argonne, IL (United States). Nuclear Engineering Div.; Bergeron, A. [Argonne National Laboratory (ANL), Argonne, IL (United States). Nuclear Engineering Div.; Dionne, B. [Argonne National Laboratory (ANL), Argonne, IL (United States). Nuclear Engineering Div.; Thomas, F. [Institut Laue-Langevin (ILL), Grenoble (Switzerland). RHF Reactor Dept.

    2014-08-01

    The purpose of this document is to describe the current state of the RELAP5 model for the Institut Laue-Langevin High Flux Reactor (RHF) located in Grenoble, France, and provide an update to the key information required to complete, for example, simulations for a loss of offsite power (LOOP) accident. A previous status report identified a list of 22 items to be resolved in order to complete the RELAP5 model. Most of these items have been resolved by ANL and the RHF team. Enough information was available to perform preliminary safety analyses and define the key items that are still required. Section 2 of this document describes the RELAP5 model of RHF. The final part of this section briefly summarizes previous model issues and resolutions. Section 3 of this document describes preliminary LOOP simulations for both HEU and LEU fuel at beginning of cycle conditions.