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Sample records for pre-post study design

  1. Emergency department transfers and hospital admissions from residential aged care facilities: a controlled pre-post design study.

    Science.gov (United States)

    Hullick, Carolyn; Conway, Jane; Higgins, Isabel; Hewitt, Jacqueline; Dilworth, Sophie; Holliday, Elizabeth; Attia, John

    2016-05-12

    Older people living in Residential Aged Care Facilities (RACF) are a vulnerable, frail and complex population. They are more likely than people who reside in the community to become acutely unwell, present to the Emergency Department (ED) and require admission to hospital. For many, hospitalisation carries with it risks. Importantly, evidence suggests that some admissions are avoidable. A new collaborative model of care, the Aged Care Emergency Service (ACE), was developed to provide clinical support to nurses in the RACFs, allowing residents to be managed in place and avoid transfer to the ED. This paper examines the effects of the ACE service on RACF residents' transfer to hospital using a controlled pre-post design. Four intervention RACFs were matched with eight control RACFs based on number of total beds, dementia specific beds, and ratio of high to low care beds in Newcastle, Australia, between March and November 2011. The intervention consisted of a clinical care manual to support care along with a nurse led telephone triage line, education, establishing goals of care prior to ED transfer, case management when in the ED, along with the development of collaborative relationships between stakeholders. Outcomes included ED presentations, length of stay, hospital admission and 28-day readmission pre- and post-intervention. Generalised estimating equations were used to estimate mean differences in outcomes between intervention and controls RACFs, pre- and post-intervention means, and their interaction, accounting for repeated measures and adjusting for matching factors. Residents had a mean age of 86 years. ED presentations ranged between 16 and 211 visits/100 RACF beds/year across all RACFs. There was no overall reduction in ED presentations (OR = 1.17, p = 0.56) with the ACE intervention. However, when compared to the controls, the intervention group reduced their ED length of stay by 45 min (p = 0.0575), and was 40 % less likely to be admitted

  2. Effects of Newly Designed Hospital Buildings on Staff Perceptions: A Pre-Post Study to Validate Design Decisions.

    Science.gov (United States)

    Schreuder, Eliane; van Heel, Liesbeth; Goedhart, Rien; Dusseldorp, Elise; Schraagen, Jan Maarten; Burdorf, Alex

    2015-01-01

    This study investigates effects of the newly built nonpatient-related buildings of a large university medical center on staff perceptions and whether the design objectives were achieved. The medical center is gradually renewing its hospital building area of 200,000 m.(2) This redevelopment is carefully planned and because lessons learned can guide design decisions of the next phase, the medical center is keen to evaluate the performance of the new buildings. A pre- and post-study with a control group was conducted. Prior to the move to the new buildings an occupancy evaluation was carried out in the old setting (n = 729) (pre-study). Post occupation of the new buildings another occupancy evaluation (post-study) was carried out in the new setting (intervention group) and again in some old settings (control group) (n = 664). The occupancy evaluation consisted of an online survey that measured the perceived performance of different aspects of the building. Longitudinal multilevel analysis was used to compare the performance of the old buildings with the new buildings. Significant improvements were found in indoor climate, perceived safety, working environment, well-being, facilities, sustainability, and overall satisfaction. Commitment to the employer, working atmosphere, orientation, work performance, and knowledge sharing did not improve. The results were interpreted by relating them to specific design choices. We showed that it is possible to measure the performance improvements of a complex intervention being a new building design and validate design decisions. A focused design process aiming for a safe, pleasant and sustainable building resulted in actual improvements in some of the related performance measures. © The Author(s) 2015.

  3. Effects of newly designed hospital buildings on staff perceptions : a pre-post study to validate design decisions

    NARCIS (Netherlands)

    Schreuder, E.J.A.; Heel, L. van; Goedhart, R.; Dusseldorp, E.; Schraagen, J.M.C.; Burdorf, A.

    2015-01-01

    Objective: This study investigates effects of the newly built nonpatient-related buildings of a large university medical center on staff perceptions and whether the design objectives were achieved. Background: The medical center is gradually renewing its hospital building area of 200,000 m.(2) This

  4. Capacity-building and clinical competence in infectious disease in Uganda: a mixed-design study with pre/post and cluster-randomized trial components.

    Directory of Open Access Journals (Sweden)

    Marcia R Weaver

    Full Text Available TRIAL DESIGN: Best practices for training mid-level practitioners (MLPs to improve global health-services are not well-characterized. Two hypotheses were: 1 Integrated Management of Infectious Disease (IMID training would improve clinical competence as tested with a single arm, pre-post design, and 2 on-site support (OSS would yield additional improvements as tested with a cluster-randomized trial. METHODS: Thirty-six Ugandan health facilities (randomized 1∶1 to parallel OSS and control arms enrolled two MLPs each. All MLPs participated in IMID (3-week core course, two 1-week boost sessions, distance learning. After the 3-week course, OSS-arm trainees participated in monthly OSS. Twelve written case scenarios tested clinical competencies in HIV/AIDS, tuberculosis, malaria, and other infectious diseases. Each participant completed different randomly-assigned blocks of four scenarios before IMID (t0, after 3-week course (t1, and after second boost course (t2, 24 weeks after t1. Scoring guides were harmonized with IMID content and Ugandan national policy. Score analyses used a linear mixed-effects model. The primary outcome measure was longitudinal change in scenario scores. RESULTS: Scores were available for 856 scenarios. Mean correct scores at t0, t1, and t2 were 39.3%, 49.1%, and 49.6%, respectively. Mean score increases (95% CI, p-value for t0-t1 (pre-post period and t1-t2 (parallel-arm period were 12.1 ((9.6, 14.6, p<0.001 and -0.6 ((-3.1, +1.9, p = 0.647 percent for OSS arm and 7.5 ((5.0, 10.0, p<0.001 and 1.6 ((-1.0, +4.1, p = 0.225 for control arm. The estimated mean difference in t1 to t2 score change, comparing arm A (participated in OSS vs. arm B was -2.2 ((-5.8, +1.4, p = 0.237. From t0-t2, mean scores increased for all 12 scenarios. CONCLUSIONS: Clinical competence increased significantly after a 3-week core course; improvement persisted for 24 weeks. No additional impact of OSS was observed. Data on clinical practice

  5. Intradialytic Laughter Yoga therapy for haemodialysis patients: a pre-post intervention feasibility study.

    Science.gov (United States)

    Bennett, Paul N; Parsons, Trisha; Ben-Moshe, Ros; Neal, Merv; Weinberg, Melissa K; Gilbert, Karen; Ockerby, Cherene; Rawson, Helen; Herbu, Corinne; Hutchinson, Alison M

    2015-06-09

    Laughter Yoga consists of physical exercise, relaxation techniques and simulated vigorous laughter. It has been associated with physical and psychological benefits for people in diverse clinical and non-clinical settings, but has not yet been tested in a haemodialysis setting. The study had three aims: 1) to examine the feasibility of conducting Laughter Yoga for patients with end stage kidney disease in a dialysis setting; 2) to explore the psychological and physiological impact of Laughter Yoga for these patients; and 3) to estimate the sample size required for future research. Pre/post intervention feasibility study. Eighteen participants were recruited into the study and Laughter Yoga therapists provided a four week intradialytic program (30-min intervention three times per week). Primary outcomes were psychological items measured at the first and last Laughter Yoga session, including: quality of life; subjective wellbeing; mood; optimism; control; self-esteem; depression, anxiety and stress. Secondary outcomes were: blood pressure, intradialytic hypotensive episodes and lung function (forced expiratory volume). Dialysis nurses exposed to the intervention completed a Laughter Yoga attitudes and perceptions survey (n = 11). Data were analysed using IBM SPSS Statistics v22, including descriptive and inferential statistics, and sample size estimates were calculated using G*Power. One participant withdrew from the study for medical reasons that were unrelated to the study during the first week (94 % retention rate). There were non-significant increases in happiness, mood, and optimism and a decrease in stress. Episodes of intradialytic hypotension decreased from 19 pre and 19 during Laughter Yoga to 4 post Laughter Yoga. There was no change in lung function or blood pressure. All nurses agreed or strongly agreed that Laughter Yoga had a positive impact on patients' mood, it was a feasible intervention and they would recommend Laughter Yoga to their patients. Sample

  6. A Pre-/Post-Disaster Epidemiological Study of Mental Health Functioning in Vietnam’s Da Nang Province Following Typhoon Xangsane

    Science.gov (United States)

    Acierno, Ron; Amstadter, Ananda B.; Gros, Daniel F.; Richardson, Lisa; Kilpatrick, Dean G.; Trung, Lam Tu; Tuan, Tran; Buoi, La Thi; Ha, Tran Thu; Thach, Tran Duc; Gaboury, Mario T.; Tran, Trinh Luong; Tam, Nguyen Thanh; Seymour, Anne; Galea, Sandro

    2010-01-01

    In 2006, typhoon Xangsane struck Vietnam and disrupted a large-scale mental health needs analysis in the Da Nang province of Vietnam. Recruitment of new participants was halted, and the design of study was altered to that of a pre-/post-event investigation in which 798 of the original 4,982 participants were re-interviewed. This produced the first pre-post disaster epidemiological study. Specifically, risk and protective factors were evaluated with respect to probable mental health “caseness” on the bases of the World Health Organization Short Response Questionnaire (SRQ-20) 7/8 cutoff (i.e., scores of 8 or more). Caseness prevalence was 20.7% pre-disaster and 27.1% post-disaster. Specific risk factors associated with mental health caseness included poor health, extreme peri-disaster fear, and experienced injury. Religious affiliation appeared to be a protective factor. In contrast to US samples, gender was not predictive of outcome. PMID:20523909

  7. Mastery learning improves students skills in inserting intravenous access: a pre-post-study

    Directory of Open Access Journals (Sweden)

    Friederichs, Hendrik

    2016-08-01

    Full Text Available Objective: Inserting peripheral venous catheters (PVCs has been identified as a core competency for medical students. Because the performance – even of hygienic standards – of both students and novice physicians is frequently inadequate, medical faculties must focus on competence-based learning objectives and deliberate practice, features that are combined in mastery learning. Our aim was to determine the competency of students in inserting PVCs before and after an educational intervention. Design: This study comprised a skills assessment with pre- and post-tests of a group of third-year students who received a simulation-based intervention. A newly established curriculum involved one hour of practice at inserting PVCs on simulators. Students were required to pass a test (total 21 points, pass mark 20 points developed on the concept of mastery learning. An unannounced follow-up test was performed one week (8 days after the intervention.Setting: The simulation center of the medical faculty in Muenster.Participants: Third-year students who received the intervention.Results: One hundred and nine complete data sets were obtained from 133 students (82.5%. Most students (97.2% passed the test after the intervention (mean score increase from 15.56 to 20.50, <0.001. There was a significant decrease in students’ performance after one week (8 days: only 74.5% of participants passed this retest (mean score reduction from 20.50 to 20.06, <0.001. Conclusion: Mastery learning is an effective form of teaching practical skills to medical students, allowing a thorough preparation for the challenges of daily clinical practice.

  8. FOREIGN TRADE OF INDIA DURING PRE & POST INDEPENDENCE (STUDY OF DEVELOPMENT OF INDIA

    Directory of Open Access Journals (Sweden)

    Renu Bansal

    2012-09-01

    Full Text Available This subject is selected for study, since it is directlyconnected with the growth of our economy. In our earlierperiod after independence, more emphasis was put for tomake the country self- sufficient. However, that is true tobe more harmful for the growth of our economy. It is thenfelt that the development and growth of economy, an allencompassing, comprehensive view needs to be taken forthe overall development of the country. For this, increase inexport is of vital importance and also we have to facilitatethose imports, which are required to stimulate oureconomy.

  9. Effect of beta-alanine supplementation on the onset of blood lactate accumulation (OBLA during treadmill running: Pre/post 2 treatment experimental design

    Directory of Open Access Journals (Sweden)

    Misic Mark

    2010-05-01

    Full Text Available Abstract Background β-Alanine (βA has been shown to improve performance during cycling. This study was the first to examine the effects of βA supplementation on the onset of blood lactate accumulation (OBLA during incremental treadmill running. Methods Seventeen recreationally-active men (mean ± SE 24.9 ± 4.7 yrs, 180.6 ± 8.9 cm, 79.25 ± 9.0 kg participated in this randomized, double-blind, placebo-controlled pre/post test 2-treatment experimental design. Subjects participated in two incremental treadmill tests before and after 28 days of supplementation with either βA (6.0 g·d-1(βA, n = 8 or an equivalent dose of Maltodextrin as the Placebo (PL, n = 9. Heart rate, percent heart rate maximum (%HRmax, %VO2max@OBLA (4.0 mmol.L-1 blood lactate concentration and VO2max (L.min-1 were determined for each treadmill test. Friedman test was used to determine within group differences; and Mann-Whitney was used to determine between group differences for pre and post values (p Results The βA group experienced a significant rightward shift in HR@OBLA beats.min-1 (p 2max@OBLA increased (p 2max (L.min-1 decreased (p Conclusions βA supplementation for 28 days enhanced sub-maximal endurance performance by delaying OBLA. However, βA supplemented individuals had a reduced aerobic capacity as evidenced by the decrease in VO2max values post supplementation.

  10. Impact of an Educational Intervention to Improve Physician Adherence to Bronchiolitis Clinical Practice Guidelines: A Pre-Post Intervention Study.

    Science.gov (United States)

    Genies, Marquita C; Kim, Julia M; Pyclik, Kristina; Rossi, Suzanne; Spicyn, Natalie; Serwint, Janet R

    2017-04-01

    Bronchiolitis is the leading cause of infant hospitalizations in the United States. Despite clinical practice guidelines discouraging the utilization of non-evidence-based therapies, there continues to be wide variation in care and resource utilization. A pre-post physician focused educational intervention was conducted with the aims to reduce the use of non-evidence-based medical therapies, including bronchodilators, among patients admitted for bronchiolitis. Among patients meeting inclusion criteria (pre: n = 45; post: n = 47), bronchodilator use decreased by 50% ( P educational intervention highlighting American Academy of Pediatrics clinical practice guidelines resulted in reduced utilization of bronchodilators.

  11. Is Active Design changing the workplace? - A natural pre-post experiment looking at health behaviour and workplace perceptions.

    Science.gov (United States)

    Engelen, Lina; Chau, Josephine; Bohn-Goldbaum, Erika; Young, Sarah; Hespe, Dominique; Bauman, Adrian

    2017-01-01

    Active Design is a relatively new concept and evaluation on its effects on healthy behaviour is lacking. To investigate Active Design influence on workplace physical activity, sedentary behaviour, musculoskeletal complaints, and perceptions of the workplace and productivity. Participants (n = 118 adults) moving from 14 workplaces into a new building completed an online questionnaire pre- and post-move. The questions related to health behaviours (physical activity, sitting time and sleep); musculoskeletal issues; perceptions of the office environment; productivity; and engagement. After the move, 68% of participants were located in an open plan building (21% before the move). In the new workplace participants tended to sit less during their work time (72% - 66%; p health-promoting effects on occupants. Satisfaction with environmental characteristics tended to improve in the new building though perceptions of productivity measures were variable.

  12. Effectiveness of interprofessional education by on-field training for medical students, with a pre-post design.

    Science.gov (United States)

    Zanotti, Renzo; Sartor, Giada; Canova, Cristina

    2015-07-29

    Interprofessional Education (IPE) implies how to achieve successful teamwork, and is based on collaborative practice which enhance occasions for relationships between two or more healthcare professions. This study evaluates the effectiveness of IPE in changing attitudes after a training recently introduced to medical education for second-year students at the University of Padova, Italy. All medical students following a new program for IPE were enrolled in this study. The Interdisciplinary Education Perception Scale (IEPS) was administered before and after training, according to observation-based and practice-based learning. Data were analysed with Student's paired t-test and Wilcoxon's signed rank test. 277 medical students completed both questionnaires. Statistically significant improvements were found in students' overall attitudes as measured by the IEPS and four subscale scores. Gender-stratified analyses showed that improvements were observed only in female students in subscale 4 ("Understanding Others' Values"). Students who had a physician and/or health worker in their family did not show any improvement in subscales 2 ("Perceived need for cooperation") or 4 ("Understanding Others' Values"). Our results indicate that IPE training has a positive influence on students' understanding of collaboration and better attitudes in interprofessional teamwork. More research is needed to explore other factors which may influence specific perceptions among medical students.

  13. 医院员工岗前培训体系设计与实践%Design and Practice of Pre-post Training System for Hospital New Employees

    Institute of Scientific and Technical Information of China (English)

    王洪国; 陈源; 王晶桐; 王杉

    2016-01-01

    新员工岗前培训是医院人才建设的重要途径,是一项系统工程。科学设计岗前培训体系要基于医院和新员工的需求分析,结合医院文化设计培训方案、组织开展系列活动,通过培训考核和满意度调查来提高岗前培训质量,同时还需要与时俱进对培训体系进行调整和完善。%Pre-post training for new employees is an important way for of hospital personnel construction, which is a systematic engineering. Scientific design of pre-post training system should base on the analysis of the needs of hospital and new employees. Training program design should combine hospital culture before carrying out series of activities. Meanwhile, improve pre-post training quality with training examination and satisfaction survey and adjust it timely.

  14. Impact of implementing electronic clinical practice guidelines for the diagnosis, control and treatment of cardiovascular risk factors: A pre-post controlled study.

    Science.gov (United States)

    Comin, Eva; Catalan-Ramos, Arantxa; Iglesias-Rodal, Manuel; Grau, Maria; Del Val, Jose Luis; Consola, Alicia; Amado, Ester; Pons, Angels; Mata-Cases, Manel; Franzi, Alicia; Ciurana, Ramon; Frigola, Eva; Cos, Xavier; Davins, Josep; Verdu-Rotellar, Jose M

    To evaluate the impact of computerized clinical practice guidelines on the management, diagnosis, treatment, control, and follow-up of the main cardiovascular risk factors: hypertension, hypercholesterolaemia, and type 2 diabetes mellitus. Pre-post controlled study. Catalonia, autonomous community located in north-eastern Spain. Individuals aged 35-74 years assigned to general practitioners of the Catalan Health Institute. The intervention group consisted of individuals whose general practitioners had accessed the computerized clinical practice guidelines at least twice a day, while the control group consisted of individuals whose general practitioner had never accessed the computerized clinical practice guidelines platform. The Chi-squared test was used to detect significant differences in the follow-up, control, and treatment variables for all three disorders (hypertension, hypercholesterolaemia, and type 2 diabetes mellitus) between individuals assigned to users and non-users of the computerized clinical practice guidelines, respectively. A total of 189,067 patients were included in this study, with a mean age of 56 years (standard deviation 12), and 55.5% of whom were women. Significant differences were observed in hypertension management, treatment and control; type 2 diabetes mellitus management, treatment and diagnoses, and the management and control of hypercholesterolaemia in both sexes. Computerized clinical practice guidelines are an effective tool for the control and follow-up of patients diagnosed with hypertension, type 2 diabetes mellitus, and hypercholesterolaemia. The usefulness of computerized clinical practice guidelines to diagnose and adequately treat individuals with these disorders remains unclear. Copyright © 2016 Elsevier España, S.L.U. All rights reserved.

  15. Can A Complex Online Intervention Improve Cancer Nurses' Pain Screening and Assessment Practices? Results from a Multicenter, Pre-post Test Pilot Study.

    Science.gov (United States)

    Phillips, Jane L; Heneka, Nicole; Hickman, Louise; Lam, Lawrence; Shaw, Tim

    2017-04-01

    Unrelieved cancer pain has an adverse impact on quality of life. While routine screening and assessment forms the basis of effective cancer pain management, it is often poorly done, thus contributing to the burden of unrelieved cancer pain. The aim of this study was to test the impact of an online, complex, evidence-based educational intervention on cancer nurses' pain assessment capabilities and adherence to cancer pain screening and assessment guidelines. Specialist inpatient cancer nurses in five Australian acute care settings participated in an intervention combining an online spaced learning cancer pain assessment module with audit and feedback of pain assessment practices. Participants' self-perceived pain assessment competencies were measured at three time points. Prospective, consecutive chart audits were undertaken to appraise nurses' adherence with pain screening and assessment guidelines. The differences in documented pre-post pain assessment practices were benchmarked and fed back to all sites post intervention. Data were analyzed using inferential statistics. Participants who completed the intervention (n = 44) increased their pain assessment knowledge, assessment tool knowledge, and confidence undertaking a pain assessment (p nurses' pain assessment capabilities translated into a significant increasing linear trend in the proportion of documented pain assessments in patients' charts at the three time points (χ(2) trend = 18.28, df = 1, p pain assessment audit and feedback data, improves inpatient cancer nurses' self-perceived pain screening and assessment capabilities and strengthens cancer pain guideline adherence. Copyright © 2017 American Society for Pain Management Nursing. Published by Elsevier Inc. All rights reserved.

  16. Assessment of the quality of antenatal care services provided by health workers using a mobile phone decision support application in northern Nigeria: a pre/post-intervention study.

    Directory of Open Access Journals (Sweden)

    Marion McNabb

    Full Text Available Given the shortage of skilled healthcare providers in Nigeria, frontline community health extension workers (CHEWs are commonly tasked with providing maternal and child health services at primary health centers. In 2012, we introduced a mobile case management and decision support application in twenty primary health centers in northern Nigeria, and conducted a pre-test/post-test study to assess whether the introduction of the app had an effect on the quality of antenatal care services provided by this lower-level cadre.Using the CommCare mobile platform, the app dynamically guides CHEWs through antenatal care protocols and collects client data in real time. Thirteen health education audio clips are also embedded in the app for improving and standardizing client counseling. To detect changes in quality, we developed an evidence-based quality score consisting of 25 indicators, and conducted a total of 266 client exit interviews. We analyzed baseline and endline data to assess changes in the overall quality score as well as changes in the provision of key elements of antenatal care.Overall, the quality score increased from 13.3 at baseline to 17.2 at endline (p<0.0001, out of a total possible score of 25, with the most significant improvements related to health counseling, technical services provided, and quality of health education.These study results suggest that the introduction of a low-cost mobile case management and decision support application can spur behavior change and improve the quality of services provided by a lower level cadre of healthcare workers. Future research should employ a more rigorous experimental design to explore potential longer-term effects on client health outcomes.

  17. Design of Pre-post Training and Testing System for Coal Miner%煤矿入井人员岗前培训考试系统的设计

    Institute of Scientific and Technical Information of China (English)

    贺耀宜

    2012-01-01

    针对煤矿现有入井人员考勤系统与安全培训系统相互独立、安全培训效果差的问题,提出了一种煤矿入井人员岗前培训考试系统的设计方案,给出了系统组成、工作流程及主要功能.该系统采用B/S、C/S混合模式开发,以统一门户管理方式与安全量化管理系统和虹膜考勤系统有机集成,并采用先考试后考勤的人员入井管理方式,即只有通过考试的人员才可下井.实际应用表明,该系统提高了煤矿企业职工学习安全知识的主动性和煤矿安全培训的有效性,为煤矿安全管理培训提供了一种新的思路与方法.%In order to solve problems that existing safety training system of coal mine is independent of welling attendance system and has poor training effect, the paper proposed a design scheme of pre-post training and testing system for coal miner, and gave structure, working process and main functions of the system. The system uses mixed development mode of B/S and C/S, integrates safety quantification management system and iris attendance system through unified portal management mode, and adopts welling management method of examination before attendance, namely the miners only passing examination can go underground. The application showed that the system improves initiative of miners for learning safety rules and validity of safety training of coal mine, which provides a new method of safety management and training of coal mine.

  18. Effects of jump and balance training on knee kinematics and electromyography of female basketball athletes during a single limb drop landing: pre-post intervention study

    OpenAIRE

    2011-01-01

    Abstract Background Some research studies have investigated the effects of anterior cruciate ligament (ACL) injury prevention programs on knee kinematics during landing tasks; however the results were different among the studies. Even though tibial rotation is usually observed at the time of ACL injury, the effects of training programs for knee kinematics in the horizontal plane have not yet been analyzed. The purpose of this study was to determine the effects of a jump and balance training p...

  19. Effects of jump and balance training on knee kinematics and electromyography of female basketball athletes during a single limb drop landing: pre-post intervention study

    Directory of Open Access Journals (Sweden)

    Nagano Yasuharu

    2011-07-01

    Full Text Available Abstract Background Some research studies have investigated the effects of anterior cruciate ligament (ACL injury prevention programs on knee kinematics during landing tasks; however the results were different among the studies. Even though tibial rotation is usually observed at the time of ACL injury, the effects of training programs for knee kinematics in the horizontal plane have not yet been analyzed. The purpose of this study was to determine the effects of a jump and balance training program on knee kinematics including tibial rotation as well as on electromyography of the quadriceps and hamstrings in female athletes. Methods Eight female basketball athletes participated in the experiment. All subjects performed a single limb landing at three different times: the initial test, five weeks later, and one week after completing training. The jump and balance training program lasted for five weeks. Knee kinematics and simultaneous electromyography of the rectus femoris and Hamstrings before training were compared with those measured after completing the training program. Results After training, regarding the position of the knee at foot contact, the knee flexion angle for the Post-training trial (mean (SE: 24.4 (2.1 deg was significantly larger than that for the Pre-training trial (19.3 (2.5 deg (p Conclusions The jump and balance training program successfully increased knee flexion and hamstring activity of female athletes during landing, and has the possibility of producing partial effects to avoid the characteristic knee position observed in ACL injury, thereby preventing injury. However, the expected changes in frontal and transverse kinematics of the knee were not observed.

  20. Effect of the new maternity insurance scheme on medical expenditures for caesarean delivery in Wuxi, China: a retrospective pre/post-reform case study.

    Science.gov (United States)

    Chen, Chun; Cheng, Zhihong; Jiang, Ping; Sun, Mei; Zhang, Qi; Lv, Jun

    2016-12-01

    Aiming to control rising medical expenditures and help improve China's healthcare systems, this study examined whether a cap-based medical insurance scheme with shared financial interest between the insurance and healthcare providers is effective in containing hospitals' C-section medical expenditures. We used 6547 caesarean delivery case records from a teaching tertiary-level general public hospital located in Wuxi, China (2004-2013), and used the Chow test to investigate the possibility of significant variation in mean medical expenditures for caesarean deliveries pre- and post-reform. We also used paired sample t-tests and linear regression models to compare the mean medical expenditures between insured and uninsured women undergoing caesarean delivery during the post-reform period. After the scheme's implementation, medical expenditures for caesarean deliveries declined and the medical expenditures of women covered by the scheme were significantly lower than those of uninsured patients. These findings indicated the scheme's effectiveness in minimizing caesarean delivery expenditures. The cap-based medical insurance scheme with shared financial interest between insurance and healthcare providers would likely steer healthcare providers' behaviors in a more cost-effective direction.

  1. What is the impact of an electronic test result acknowledgement system on Emergency Department physicians' work processes? A mixed-method pre-post observational study.

    Science.gov (United States)

    Georgiou, Andrew; McCaughey, Euan J; Tariq, Amina; Walter, Scott R; Li, Julie; Callen, Joanne; Paoloni, Richard; Runciman, William B; Westbrook, Johanna I

    2017-03-01

    To examine the impact of an electronic Results Acknowledgement (eRA) system on emergency physicians' test result management work processes and the time taken to acknowledge microbiology and radiology test results for patients discharged from an Emergency Department (ED). The impact of the eRA system was assessed in an Australian ED using: a) semi-structured interviews with senior emergency physicians; and b) a time and motion direct observational study of senior emergency physicians completing test acknowledgment pre and post the implementation of the eRA system. The eRA system led to changes in the way results and actions were collated, stored, documented and communicated. Although there was a non-significant increase in the average time taken to acknowledge results in the post period, most types of acknowledgements (other than simple acknowledgements) took less time to complete. The number of acknowledgements where physicians sought additional information from the Electronic Medical Record (EMR) rose from 12% pre to 20% post implementation of eRA. Given that the type of results are unlikely to have changed significantly across the pre and post implementation periods, the increase in the time physicians spent accessing additional clinical information in the post period likely reflects the greater access to clinical information provided by the integrated electronic system. Easier access to clinical information may improve clinical decision making and enhance the quality of patient care. For instance, in situations where a senior clinician, not initially involved in the care process, is required to deal with the follow-up of non-normal results. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  2. The Facilitative Effect of Transcranial Direct Current Stimulation on Visuospatial Working Memory in Patients with Diabetic Polyneuropathy: A Pre-post Sham-Controlled Study.

    Science.gov (United States)

    Wu, Yi-Jen; Tseng, Philip; Huang, Han-Wei; Hu, Jon-Fan; Juan, Chi-Hung; Hsu, Kuei-Sen; Lin, Chou-Ching

    2016-01-01

    Diabetes mellitus can lead to diabetic polyneuropathy (DPN) and cognitive deficits that manifest as peripheral and central neuropathy, respectively. In this study we investigated the relationship between visuospatial working memory (VSWM) capacity and DPN severity, and attempted to improve VSWM in DPN patients via the use of transcranial direct current stimulation (tDCS). Sixteen DPN patients and 16 age- and education-matched healthy control subjects received Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) and Montreal Cognitive Assessment (MOCA) for baseline cognitive assessment. A forward- and backward-recall computerized Corsi block tapping task (CBT), both with and without a concurrent motor interference task was used to measure VSWM capacity. Each DPN patient underwent a pre-treatment CBT, followed by tDCS or sham treatment, then a post-treatment CBT on two separate days. We found that although patients with severe DPN (Dyck's grade 2a or 2b) showed comparable general intelligence scores on WAIS-IV as their age- and education-matched healthy counterparts, they nonetheless showed mild cognitive impairment (MCI) on MOCA and working memory deficit on digit-span test of WAIS-IV. Furthermore, patients' peripheral nerve conduction velocity (NCV) was positively correlated with their VSWM span in the most difficult CBT condition that involved backward-recall with motor interference such that patients with worse NCV also had lower VSWM span. Most importantly, anodal tDCS over the right DLPFC was able to improve low-performing patients' VSWM span to be on par with the high-performers, thereby eliminating the correlation between NCV and VSWM. In summary, these findings suggest that (1) MCI and severe peripheral neuropathy can coexist with unequal severity in diabetic patients, (2) the positive correlation of VSWM and NCV suggests a link between peripheral and central neuropathies, and (3) anodal tDCS over the right DLPFC can improve DPN patients' VSWM

  3. Effectiveness of resistance training in combination with botulinum toxin-A on hand and arm use in children with cerebral palsy: a pre-post intervention study.

    Science.gov (United States)

    Elvrum, Ann-Kristin G; Brændvik, Siri M; Sæther, Rannei; Lamvik, Torarin; Vereijken, Beatrix; Roeleveld, Karin

    2012-07-02

    The aim of this pilot study was to examine the effects of additional resistance training after use of Botulinum Toxin-A (BoNT-A) on the upper limbs in children with cerebral palsy (CP). Ten children with CP (9-17 years) with unilaterally affected upper limbs according to Manual Ability Classification System II were assigned to two intervention groups. One group received BoNT-A treatment (group B), the other BoNT-A plus eight weeks resistance training (group BT). Hand and arm use were evaluated by means of the Melbourne assessment of unilateral upper limb function (Melbourne) and Assisting Hand Assessment (AHA). Measures of muscle strength, muscle tone, and active range of motion were used to assess neuromuscular body function. Measurements were performed before and two and five months after intervention start. Change scores and differences between the groups in such scores were subjected to Mann-Whitney U and Wilcoxon Signed Rank tests, respectively. Both groups had very small improvements in AHA and Melbourne two months after BoNT-A injections, without differences between groups. There were significant, or close to significant, short-term treatment effects in favour of group BT for muscle strength in injected muscles (elbow flexion strength, p = .08) and non-injected muscles (elbow extension and supination strength, both p = .05), without concomitant increases in muscle tone. Active supination range improved in both groups, but more so in group BT (p = .09). There were no differences between the groups five months after intervention start. Resistance training strengthens non-injected muscles temporarily and may reduce short-term strength loss that results from BoNT-A injections without increasing muscle tone. Moreover, additional resistance training may increase active range of motion to a greater extent than BoNT-A alone. None of the improvements in neuromuscular impairments further augmented use of the hand and arm. Larger clinical trials are needed to

  4. Effectiveness of resistance training in combination with botulinum toxin-A on hand and arm use in children with cerebral palsy: a pre-post intervention study

    Directory of Open Access Journals (Sweden)

    Elvrum Ann-Kristin G

    2012-07-01

    Full Text Available Abstract Background The aim of this pilot study was to examine the effects of additional resistance training after use of Botulinum Toxin-A (BoNT-A on the upper limbs in children with cerebral palsy (CP. Methods Ten children with CP (9–17 years with unilaterally affected upper limbs according to Manual Ability Classification System II were assigned to two intervention groups. One group received BoNT-A treatment (group B, the other BoNT-A plus eight weeks resistance training (group BT. Hand and arm use were evaluated by means of the Melbourne assessment of unilateral upper limb function (Melbourne and Assisting Hand Assessment (AHA. Measures of muscle strength, muscle tone, and active range of motion were used to assess neuromuscular body function. Measurements were performed before and two and five months after intervention start. Change scores and differences between the groups in such scores were subjected to Mann–Whitney U and Wilcoxon Signed Rank tests, respectively. Results Both groups had very small improvements in AHA and Melbourne two months after BoNT-A injections, without differences between groups. There were significant, or close to significant, short-term treatment effects in favour of group BT for muscle strength in injected muscles (elbow flexion strength, p = .08 and non-injected muscles (elbow extension and supination strength, both p = .05, without concomitant increases in muscle tone. Active supination range improved in both groups, but more so in group BT (p = .09. There were no differences between the groups five months after intervention start. Conclusions Resistance training strengthens non-injected muscles temporarily and may reduce short-term strength loss that results from BoNT-A injections without increasing muscle tone. Moreover, additional resistance training may increase active range of motion to a greater extent than BoNT-A alone. None of the improvements in neuromuscular impairments further

  5. The facilitative effect of transcranial direct current stimulation on visuospatial working memory in patients with diabetic polyneuropathy: a pre-post sham-controlled study

    Directory of Open Access Journals (Sweden)

    YI-JEN WU

    2016-09-01

    Full Text Available Diabetes mellitus (DM can lead to diabetic polyneuropathy (DPN and cognitive deficits that manifest as peripheral and central neuropathy, respectively. In this study we investigated the relationship between visuospatial working memory (VSWM capacity and DPN severity, and attempted to improve VSWM in DPN patients via the use of transcranial direct current stimulation (tDCS. Sixteen DPN patients and sixteen age- and education-matched healthy control subjects received Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV and Montreal Cognitive Assessment (MOCA for baseline cognitive assessment. A forward- and backward-recall computerized Corsi block tapping task (CBT, both with and without a concurrent motor interference task was used to measure VSWM capacity. Each DPN patient underwent a pre-treatment CBT, followed by tDCS or sham treatment, then a post-treatment CBT on two separate days. We found that although patients with severe DPN (Dyck’s grade 2a or 2b showed comparable general intelligence scores on WAIS-IV as their age- and education-matched healthy counterparts, they nonetheless showed mild cognitive impairment on MOCA and working memory deficit on digit-span test of WAIS-IV. Furthermore, patients’ peripheral nerve conduction velocity (NCV was positively correlated with their VSWM span in the most difficult CBT condition that involved backward-recall with motor interference such that patients with worse NCV also had lower VSWM span. Most importantly, anodal tDCS over the right DLPFC was able to improve low-performing patients’ VSWM span to be on par with the high-performers, thereby eliminating the correlation between NCV and VSWM. In summary, these findings suggest that 1 mild cognitive impairment and severe peripheral neuropathy can coexist with unequal severity in diabetic patients, 2 the positive correlation of VSWM and NCV suggests a link between peripheral and central neuropathies and 3 anodal tDCS over the right DLPFC can

  6. Pre/post-strike atmospheric assessment system (PAAS)

    Energy Technology Data Exchange (ETDEWEB)

    Peglow, S. G., LLNL; Molitoris, J. D., LLNL

    1997-02-03

    The Pre/Post-Strike Atmospheric Assessment System was proposed to show the importance of local meteorological conditions in the vicinity of a site suspected of storing or producing toxic agents and demonstrate a technology to measure these conditions, specifically wind fields. The ability to predict the collateral effects resulting from an attack on a facility containing hazardous materials is crucial to conducting effective military operations. Our study approach utilized a combination of field measurements with dispersion modeling to better understand which variables in terrain and weather were most important to collateral damage predictions. To develop the PAAS wind-sensing technology, we utilized a combination of emergent and available technology from micro-Doppler and highly coherent laser systems. The method used for wind sensing is to probe the atmosphere with a highly coherent laser beam. As the beam probes, light is back-scattered from particles entrained in the air to the lidar transceiver and detected by the instrument. Any motion of the aerosols with a component along the beam axis leads to a Doppler shift of the received light. Scanning in a conical fashion about the zenith results in a more accurate and two-dimensional measurement of the wind velocity. The major milestones in the benchtop system development were to verify the design by demonstrating the technique in the laboratory, then scale the design down to a size consistent with a demonstrator unit which could be built to take data in the field. The micro-Doppler heterodyne system we developed determines absolute motion by optically mixing a reference beam with the return signal and has shown motion sensitivity to better than 1 cm/s. This report describes the rationale, technical approach and laboratory testing undertaken to demonstrate the feasibility and utility of a system to provide local meteorological data and predict atmospheric particulate motion. The work described herein was funded by

  7. Does the Incredible Years Teacher Classroom Management Training programme have positive effects for young children exhibiting severe externalizing problems in school?: a quasi-experimental pre-post study

    Directory of Open Access Journals (Sweden)

    Bente Kirkhaug

    2016-10-01

    Full Text Available Abstract Background Young children exhibiting severe externalizing problems in school are at risk of developing several poor outcomes. School-based intervention programs have been found to be effective for students with different problems, including those with behavioral problems, emotional distress, or social problems. The present study investigated whether the IY-TCM programme, as a universal stand-alone school intervention programme, reduced severe child externalizing problems as reported by the teacher, and evaluated if these children improved their social competence, internalizing problems, academic performances and student- teacher relationship as a result of the IY TCM training. Methods A quasi-experimental pre-post study was conducted, including 21 intervention schools and 22 control schools. Children in 1st – 3rd grade (age 6–8 years assessed by their teacher as having severe externalizing problems on the Sutter–Eyberg Student Behavior Inventory-Revised (SESBI-R total Intensity score, were included in the study, N = 83 (65 boys and 18 girls. Treatment effects were evaluated using 3- level linear mixed models analysis. Results In our study we found no differences in change between the two conditions from baseline to follow-up in externalizing problems, social skills, internalizing problems and closeness with teacher. The intervention condition did however show advantageous development in terms of student-teacher conflicts and increased academic performances. Conclusion The IY Teacher Classroom Management program is not sufficient being a stand-alone universal program in a Norwegian primary school setting, for students with severe externalizing problems. However; some important secondary findings were found. Still, young school children with severe externalizing problems are in need of more comprehensive and tailored interventions.

  8. Does the Incredible Years Teacher Classroom Management Training programme have positive effects for young children exhibiting severe externalizing problems in school?: a quasi-experimental pre-post study.

    Science.gov (United States)

    Kirkhaug, Bente; Drugli, May Britt; Handegård, Bjørn Helge; Lydersen, Stian; Åsheim, Merethe; Fossum, Sturla

    2016-10-26

    Young children exhibiting severe externalizing problems in school are at risk of developing several poor outcomes. School-based intervention programs have been found to be effective for students with different problems, including those with behavioral problems, emotional distress, or social problems. The present study investigated whether the IY-TCM programme, as a universal stand-alone school intervention programme, reduced severe child externalizing problems as reported by the teacher, and evaluated if these children improved their social competence, internalizing problems, academic performances and student- teacher relationship as a result of the IY TCM training. A quasi-experimental pre-post study was conducted, including 21 intervention schools and 22 control schools. Children in 1(st) - 3(rd) grade (age 6-8 years) assessed by their teacher as having severe externalizing problems on the Sutter-Eyberg Student Behavior Inventory-Revised (SESBI-R) total Intensity score, were included in the study, N = 83 (65 boys and 18 girls). Treatment effects were evaluated using 3- level linear mixed models analysis. In our study we found no differences in change between the two conditions from baseline to follow-up in externalizing problems, social skills, internalizing problems and closeness with teacher. The intervention condition did however show advantageous development in terms of student-teacher conflicts and increased academic performances. The IY Teacher Classroom Management program is not sufficient being a stand-alone universal program in a Norwegian primary school setting, for students with severe externalizing problems. However; some important secondary findings were found. Still, young school children with severe externalizing problems are in need of more comprehensive and tailored interventions.

  9. Safety and efficacy of at-home robotic locomotion therapy in individuals with chronic incomplete spinal cord injury: a prospective, pre-post intervention, proof-of-concept study.

    Directory of Open Access Journals (Sweden)

    Rüdiger Rupp

    Full Text Available The compact Motorized orthosis for home rehabilitation of Gait (MoreGait was developed for continuation of locomotion training at home. MoreGait generates afferent stimuli of walking with the user in a semi-supine position and provides feedback about deviations from the reference walking pattern.Prospective, pre-post intervention, proof-of-concept study to test the feasibility of an unsupervised home-based application of five MoreGait prototypes in subjects with incomplete spinal cord injury (iSCI.Twenty-five (5 tetraplegia, 20 paraplegia participants with chronic (mean time since injury: 5.8 ± 5.4 (standard deviation, SD years sensorimotor iSCI (7 ASIA Impairment Scale (AIS C, 18 AIS D; Walking Index for Spinal Cord Injury (WISCI II: Interquartile range 9 to 16 completed the training (45 minutes / day, at least 4 days / week, 8 weeks. Baseline status was documented 4 and 2 weeks before and at training onset. Training effects were assessed after 4 and 8 weeks of therapy.After therapy, 9 of 25 study participants improved with respect to the dependency on walking aids assessed by the WISCI II. For all individuals, the short-distance walking velocity measured by the 10-Meter Walk Test showed significant improvements compared to baseline (100% for both self-selected (Mean 139.4% ± 35.5% (SD and maximum (Mean 143.1% ± 40.6% (SD speed conditions as well as the endurance estimated with the six-minute walk test (Mean 166.6% ± 72.1% (SD. One device-related adverse event (pressure sore on the big toe occurred in over 800 training sessions.Home-based robotic locomotion training with MoreGait is feasible and safe. The magnitude of functional improvements achieved by MoreGait in individuals with iSCI is well within the range of complex locomotion robots used in hospitals. Thus, unsupervised MoreGait training potentially represents an option to prolong effective training aiming at recovery of locomotor function beyond in-patient rehabilitation

  10. The association between retrospective outcome evaluations and pre-post-treatment changes in psychodynamic group-psychotherapy

    DEFF Research Database (Denmark)

    Jensen, Hans Henrik; Mortensen, Erik Lykke; Lotz, Martin

    2008-01-01

    In the present study of 203 patients in psychodynamic group psychotherapy, we explore associations between patient and therapist global retrospective outcome evaluations (ROE), and pre-post-treatment changes on the Symptom Check List 90 Revised (SCL-90-R) and non-symptomatic focus of therapy. The...

  11. Curriculum-Based Measurement of Oral Reading: Evaluation of Growth Estimates Derived with Pre-Post Assessment Methods

    Science.gov (United States)

    Christ, Theodore J.; Monaghen, Barbara D.; Zopluoglu, Cengiz; Van Norman, Ethan R.

    2013-01-01

    Curriculum-based measurement of oral reading (CBM-R) is used to index the level and rate of student growth across the academic year. The method is frequently used to set student goals and monitor student progress. This study examined the diagnostic accuracy and quality of growth estimates derived from pre-post measurement using CBM-R data. A…

  12. A patient's perspective on multidisciplinary treatment gain for fibromyalgia: an indicator for pre-post treatment effects?

    NARCIS (Netherlands)

    Koulil, S. van; Kraaimaat, F.W.; Lankveld, W.G.J.M. van; Riel, P.L.C.M. van; Evers, A.W.M.

    2009-01-01

    OBJECTIVE: Increasing attention is devoted to the patient's perspective in clinical research and practice. However, the relationship between the patient's view on treatment progress and standardized pre-post changes in health outcomes is not well understood. The objective of this study was to invest

  13. A patient's perspective on multidisciplinary treatment gain for fibromyalgia: an indicator for pre-post treatment effects?

    NARCIS (Netherlands)

    Koulil, S. van; Kraaimaat, F.W.; Lankveld, W.G.J.M. van; Riel, P.L.C.M. van; Evers, A.W.M.

    2009-01-01

    OBJECTIVE: Increasing attention is devoted to the patient's perspective in clinical research and practice. However, the relationship between the patient's view on treatment progress and standardized pre-post changes in health outcomes is not well understood. The objective of this study was to invest

  14. A Mobile Phone-Based Life Skills Training Program for Substance Use Prevention Among Adolescents: Pre-Post Study on the Acceptance and Potential Effectiveness of the Program, Ready4life.

    Science.gov (United States)

    Haug, Severin; Paz Castro, Raquel; Meyer, Christian; Filler, Andreas; Kowatsch, Tobias; Schaub, Michael P

    2017-10-04

    Substance use and misuse often first emerge during adolescence. Generic life skills training that is typically conducted within the school curriculum is effective at preventing the onset and escalation of substance use among adolescents. However, the dissemination of such programs is impeded by their large resource requirements in terms of personnel, money, and time. Life skills training provided via mobile phones might be a more economic and scalable approach, which additionally matches the lifestyle and communication habits of adolescents. The aim of this study was to test the acceptance and initial effectiveness of an individually tailored mobile phone-based life skills training program in vocational school students. The fully automated program, named ready4life, is based on social cognitive theory and addresses self-management skills, social skills, and substance use resistance skills. Program participants received up to 3 weekly text messages (short message service, SMS) over 6 months. Active program engagement was stimulated by interactive features such as quiz questions, message- and picture-contests, and integration of a friendly competition with prizes in which program users collected credits with each interaction. Generalized estimating equation (GEE) analyses were used to investigate for changes between baseline and 6-month follow-up in the following outcomes: perceived stress, self-management skills, social skills, at-risk alcohol use, tobacco smoking, and cannabis use. The program was tested in 118 school classes at 13 vocational schools in Switzerland. A total of 1067 students who owned a mobile phone and were not regular cigarette smokers were invited to participate in the life skills program. Of these, 877 (82.19%, 877/1067; mean age=17.4 years, standard deviation [SD]=2.7; 58.3% females) participated in the program and the associated study. A total of 43 students (4.9%, 43/877) withdrew their program participation during the intervention period

  15. Learning to Work with Databases in Astronomy: Quantitative Analysis of Science Educators' and Students' Pre-/Post-Tests

    Science.gov (United States)

    Schwortz, Andria C.; Burrows, Andrea C.; Myers, Adam D.

    2015-01-01

    Astronomy is increasingly moving towards working with large databases, from the state-of-the-art Sloan Digital Sky Survey Data Release 10, to the historical Digital Access to a Sky Century at Harvard. Non-astronomy fields as well tend to work with large datasets, be it in the form of warehouse inventory, health trends, or the stock market. However very few fields explicitly teach students the necessary skills to analyze such data. The authors studied a matched set of 37 participants working with 200-entry databases in astronomy using Google Spreadsheets, with limited information about a random set of quasars drawn from SDSS DR5. Here the authors present the quantitative results from an eight question pre-/post-test, with questions designed to span Bloom's taxonomy, on both the topics of the skills of using spreadsheets, and the content of quasars. Participants included both Astro 101 summer students and professionals including in-service K-12 teachers and science communicators. All groups showed statistically significant gains (as per Hake, 1998), with the greatest difference between women's gains of 0.196 and men's of 0.480.

  16. Breton Island Transects with Shoreline Change Rates (Pre/Post Hurricane Katrina) (Geographic, NAD83)

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Breton Island, Louisiana Transects with Shoreline Change Rates (Pre/Post Hurricane Katrina) (Geographic, NAD83) consists of vector transect data that were derived...

  17. Breton Island Transects with Shoreline Change Rates (Pre/Post Hurricane Katrina) (Geographic, NAD83)

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Breton Island, Louisiana Transects with Shoreline Change Rates (Pre/Post Hurricane Katrina) (Geographic, NAD83) consists of vector transect data that were derived...

  18. Creating Leaders: A Pilot Pre/Post Evaluation of an Ontological/Phenomenological Model

    Science.gov (United States)

    Carney, Nancy; Jensen, Michael; Ballarini, Nicolas; Echeverria, Jeronima; Nettleton, Tracie; Stillwell, Molly; Erhard, Werner

    2016-01-01

    This pilot is a pre/post comparative assessment of a leadership course developed and delivered using an innovative, ontological/phenomenological model of education. Participants in the course delivered in Singapore in July of 2014 provided measures of the effectiveness of their leadership before and after the course, using a scale from 1 (least…

  19. Stimulus Competition in Pre/Post and Online Ratings in an Evaluative Learning Design

    Science.gov (United States)

    Purkis, Helena M.; Lipp, Ottmar V.

    2010-01-01

    Evaluative learning is said to differ from Pavlovian associative learning in that it reflects stimulus contiguity, not contingency. Thus, evaluative learning should not be subject to stimulus competition, a proposal tested in the current experiments. Participants were presented in elemental and compound training phases with pictures of shapes as…

  20. Reducing child abuse amongst adolescents in low- and middle-income countries: A pre-post trial in South Africa.

    Science.gov (United States)

    Cluver, Lucie; Meinck, Franziska; Yakubovich, Alexa; Doubt, Jenny; Redfern, Alice; Ward, Catherine; Salah, Nasteha; De Stone, Sachin; Petersen, Tshiamo; Mpimpilashe, Phelisa; Romero, Rocio Herrero; Ncobo, Lulu; Lachman, Jamie; Tsoanyane, Sibongile; Shenderovich, Yulia; Loening, Heidi; Byrne, Jasmina; Sherr, Lorraine; Kaplan, Lauren; Gardner, Frances

    2016-07-13

    No known studies have tested the effectiveness of child abuse prevention programmes for adolescents in low- or middle-income countries. 'Parenting for Lifelong Health' ( http://tiny.cc/whoPLH ) is a collaborative project to develop and rigorously test abuse-prevention parenting programmes for free use in low-resource contexts. Research aims of this first pre-post trial in South Africa were: i) to identify indicative effects of the programme on child abuse and related outcomes; ii) to investigate programme safety for testing in a future randomised trial, and iii) to identify potential adaptations. Two hundred thirty participants (adolescents and their primary caregivers) were recruited from schools, welfare services and community-sampling in rural, high-poverty South Africa (no exclusion criteria). All participated in a 12-week parenting programme, implemented by local NGO childcare workers to ensure real-world external validity. Standardised pre-post measures with adolescents and caregivers were used, and paired t-tests were conducted for primary outcomes: abuse (physical, emotional abuse and neglect), adolescent behaviour problems and parenting (positive and involved parenting, poor monitoring and inconsistent discipline), and secondary outcomes: mental health, social support and substance use. Participants reported high levels of socio-economic deprivation, e.g. 60 % of adolescents had either an HIV-positive caregiver or were orphaned by AIDS, and 50 % of caregivers experienced intimate partner violence. i) indicative effects: Primary outcomes comparing pre-test and post-test assessments showed reductions reported by adolescents and caregivers in child abuse (adolescent report 63.0 % pre-test to 29.5 % post-test, caregiver report 75.5 % pre-test to 36.5 % post-test, both p child abuse and improved caregiver and adolescent outcomes. It showed high acceptability and unexpected community-level diffusion. Findings indicate needs for adaptations, and

  1. Immediate stress reduction effects of yoga during pregnancy: One group pre-post test.

    Science.gov (United States)

    Kusaka, Momoko; Matsuzaki, Masayo; Shiraishi, Mie; Haruna, Megumi

    2016-10-01

    Excessive stress during pregnancy may cause mental disorders in pregnant women and inhibit fetal growth. Yoga may alleviate stress during pregnancy. To verify the immediate effects of yoga on stress response during pregnancy. One group pre-post test was conducted at a hospital in Japan. We recruited 60 healthy primiparas without complications and asked them to attend yoga classes twice a month and to practice yoga at their homes using DVD 3 times a week from 20 gestational weeks until childbirth. Salivary cortisol and alpha-amylase concentration were measured before and after yoga classes at time 1 (27-32 gestational weeks) and time 2 (34-37 gestational weeks). Subjective mood was assessed using the profile of mood states. Saliva values and mood scores before and after each yoga class were compared using paired t-test and Wilcoxon rank-sum test, respectively. We analyzed 44 and 35 women at time 1 and time 2, respectively. The mean salivary cortisol concentration declined significantly after each yoga class [time 1: 0.36-0.26μg/dL (pstress reduction effects of yoga during pregnancy. Copyright © 2016 Australian College of Midwives. Published by Elsevier Ltd. All rights reserved.

  2. Pre/post-closure assessment of groundwater pharmaceutical fate in a wastewater‑facility-impacted stream reach

    Science.gov (United States)

    Bradley, Paul M.; Barber, Larry B.; Clark, Jimmy M.; Duris, Joseph; Foreman, William; Furlong, Edward T.; Givens, Carrie E.; Hubbard, Laura E.; Hutchinson, Kasey J.; Journey, Celeste A.; Keefe, Steffanie H.; Kolpin, Dana W.

    2016-01-01

    Pharmaceutical contamination of contiguous groundwater is a substantial concern in wastewater-impacted streams, due to ubiquity in effluent, high aqueous mobility, designed bioactivity, and to effluent-driven hydraulic gradients. Wastewater treatment facility (WWTF) closures are rare environmental remediation events; offering unique insights into contaminant persistence, long-term wastewater impacts, and ecosystem recovery processes. The USGS conducted a combined pre/post-closure groundwater assessment adjacent to an effluent-impacted reach of Fourmile Creek, Ankeny, Iowa, USA. Higher surface-water concentrations, consistent surface-water to groundwater concentration gradients, and sustained groundwater detections tens of meters from the stream bank demonstrated the importance of WWTF effluent as the source of groundwater pharmaceuticals as well as the persistence of these contaminants under effluent-driven, pre-closure conditions. The number of analytes (110 total) detected in surface water decreased from 69 prior to closure down to 8 in the first post-closure sampling event approximately 30 d later, with a corresponding 2 order of magnitude decrease in the cumulative concentration of detected analytes. Post-closure cumulative concentrations of detected analytes were approximately 5 times higher in proximal groundwater than in surface water. About 40% of the 21 contaminants detected in a downstream groundwater transect immediately before WWTF closure exhibited rapid attenuation with estimated half-lives on the order of a few days; however, a comparable number exhibited no consistent attenuation during the year-long post-closure assessment. The results demonstrate the potential for effluent-impacted shallow groundwater systems to accumulate pharmaceutical contaminants and serve as long-term residual sources, further increasing the risk of adverse ecological effects in groundwater and the near-stream ecosystem.

  3. The impact of evidence-based sepsis guidelines on emergency department clinical practice: a pre-post medical record audit.

    Science.gov (United States)

    Romero, Bernadine; Fry, Margaret; Roche, Michael

    2017-01-10

    To explore the number of patients presenting with sepsis before and after guideline implementation; the impact of sepsis guidelines on triage assessment, emergency department management and time to antibiotics. Sepsis remains one of the leading causes of mortality and morbidity within hospitals. Globally, strategies have been implemented to reduce morbidity and mortality rates, which rely on the early recognition and management of sepsis. To improve patient outcomes, the New South Wales government in Australia introduced sepsis guidelines into emergency departments. However, the impact of the guidelines on clinical practice remains unclear. A 12-month pre-post retrospective randomised medical record audit of adult patients with a sepsis diagnosis. Data were extracted from the emergency department database and paper medical record. Data included patient demographic (age, gender), clinical information (time of arrival, triage code, seen by time, disposition, time to antibiotic, pathology, time to intravenous fluids) and patient assessment data (heart rate, respiratory rate, blood pressure, temperature, oxygen saturations, medication). This study demonstrated a statistically significant 230-minute reduction in time to antibiotics post implementation of the guidelines. The post group (n = 165) received more urgent triage categories (n = 81; 49·1%), a 758-minute reduction in mean time to second litre of intravenous fluids and an improvement in collection of lactate (n = 112, 67·9%), also statistically significant. The findings highlight the impact the guidelines can have on clinician decision-making and behaviour that support best practice and positive patient outcomes. The sepsis guidelines improved the early assessment, recognition and management of patients presenting with sepsis in one tertiary referral emergency department. The use of evidenced-based guidelines can impact clinical decision-making and behaviour, resulting in the translation and support of

  4. Using Robotics and Game Design to Enhance Children's Self-Efficacy, STEM Attitudes, and Computational Thinking Skills

    Science.gov (United States)

    Leonard, Jacqueline; Buss, Alan; Gamboa, Ruben; Mitchell, Monica; Fashola, Olatokunbo S.; Hubert, Tarcia; Almughyirah, Sultan

    2016-01-01

    This paper describes the findings of a pilot study that used robotics and game design to develop middle school students' computational thinking strategies. One hundred and twenty-four students engaged in LEGO® EV3 robotics and created games using Scalable Game Design software. The results of the study revealed students' pre-post self-efficacy…

  5. Designing satisfaction studies

    DEFF Research Database (Denmark)

    Kristensen, Kai; Eskildsen, Jacob Kjær

    2007-01-01

    In the effect sampling method, presentation of researcher, the intro text, the order of questions in the questionnaire along with the number of categories in the rating scale is tested in relation to the design of satisfaction studies. Based on the analyses specific recommendations for designing...... satisfaction studies are given....

  6. The Scope of Design Studying

    Institute of Scientific and Technical Information of China (English)

    JIN Yin; Ren Wenying

    2007-01-01

    This article trys to discuss the scope of design studying in two fields.Firstly, design has three meanings: wide design, art design and industrial design.Secondly, design studying has five contents: cultural, philosophical, methodological, produced and marketable trends.

  7. A review of dissociative disorders treatment studies.

    Science.gov (United States)

    Brand, Bethany L; Classen, Catherine C; McNary, Scot W; Zaveri, Parin

    2009-09-01

    This review examines empirical reports of treatment for Dissociative Disorders (DD), including 16 DD treatment outcome studies and 4 case studies that used standardized measures. Collectively, these reports suggest that treatment for DD is associated with decreased symptoms of dissociation, depression, posttraumatic stress disorder, distress, and suicidality. Effect sizes, based on pre/post measures, are in the medium to large range across studies. Patients with dissociative disorder who integrated their dissociated self states were found to have reduced symptomatology compared with those who did not integrate. The magnitude of pre/post effect sizes for these DD studies are comparable to pre/post effect sizes in treatment studies of complex PTSD. There are significant methodological limitations in the current DD treatment outcome literature that reduce internal and external validity including regression towards the mean, limited sample sizes, and nonrandomized research designs. Implications for future research and treatment planning for patients suffering from DD are discussed.

  8. Design and data analysis 1 study design

    Directory of Open Access Journals (Sweden)

    Karthik Suresh

    2012-01-01

    Full Text Available This article is intended to give the reader guidance in evaluating different study designs used in medical research for better scientific quality, reliability and validity of their research. This article explains three main types of study designs with understanding examples. Care and caution with skills and experience needed to design suitable studies and appropriate design coupled with reliable sampling techniques and appropriate statistical analysis, supported by clear objectives with decent communication of the findings, are essential for good research.

  9. A controlled study of the short- and long-term effects of a Train the Trainers course

    DEFF Research Database (Denmark)

    Rubak, S.; Mortensen, L.; Ringsted, C.

    2008-01-01

    Objectives This study aimed to establish the longterm effects of a 3-day 'Training for Trainers' course (TTC) on doctors' knowledge, teaching behaviour and clinical learning climate. Methods The study was designed as an intervention study with pre-, post- and long-term measurements. The intervent......Objectives This study aimed to establish the longterm effects of a 3-day 'Training for Trainers' course (TTC) on doctors' knowledge, teaching behaviour and clinical learning climate. Methods The study was designed as an intervention study with pre-, post- and long-term measurements...

  10. Slurry reactor design studies

    Energy Technology Data Exchange (ETDEWEB)

    Fox, J.M.; Degen, B.D.; Cady, G.; Deslate, F.D.; Summers, R.L. (Bechtel Group, Inc., San Francisco, CA (USA)); Akgerman, A. (Texas A and M Univ., College Station, TX (USA)); Smith, J.M. (California Univ., Davis, CA (USA))

    1990-06-01

    The objective of these studies was to perform a realistic evaluation of the relative costs of tublar-fixed-bed and slurry reactors for methanol, mixed alcohols and Fischer-Tropsch syntheses under conditions where they would realistically be expected to operate. The slurry Fischer-Tropsch reactor was, therefore, operated at low H{sub 2}/CO ratio on gas directly from a Shell gasifier. The fixed-bed reactor was operated on 2.0 H{sub 2}/CO ratio gas after adjustment by shift and CO{sub 2} removal. Every attempt was made to give each reactor the benefit of its optimum design condition and correlations were developed to extend the models beyond the range of the experimental pilot plant data. For the methanol design, comparisons were made for a recycle plant with high methanol yield, this being the standard design condition. It is recognized that this is not necessarily the optimum application for the slurry reactor, which is being proposed for a once-through operation, coproducing methanol and power. Consideration is also given to the applicability of the slurry reactor to mixed alcohols, based on conditions provided by Lurgi for an Octamix{trademark} plant using their standard tubular-fixed reactor technology. 7 figs., 26 tabs.

  11. Seal design alternatives study

    Energy Technology Data Exchange (ETDEWEB)

    Van Sambeek, L.L. [RE/SPEC Inc., Rapid City, SD (US); Luo, D.D.; Lin, M.S.; Ostrowski, W.; Oyenuga, D. [Parsons Brinckerhoff Quade & Douglas, Inc., San Francisco, CA (US)

    1993-06-01

    This report presents the results from a study of various sealing alternatives for the WIPP sealing system. Overall, the sealing system has the purpose of reducing to the extent possible the potential for fluids (either gas or liquid) from entering or leaving the repository. The sealing system is divided into three subsystems: drift and panel seals within the repository horizon, shaft seals in each of the four shafts, and borehole seals. Alternatives to the baseline configuration for the WIPP seal system design included evaluating different geometries and schedules for seal component installations and the use of different materials for seal components. Order-of-magnitude costs for the various alternatives were prepared as part of the study. Firm recommendations are not presented, but the advantages and disadvantages of the alternatives are discussed. Technical information deficiencies are identified and studies are outlined which can provide required information.

  12. A Dataset for Education-Related Majors' Performance Measures with Pre/Post-Video Game Practice

    Science.gov (United States)

    Novak, Elena; Tassell, Janet Lynne

    2015-01-01

    This dataset includes a series of 30 education-related majors' performance measures before and after they completed a 10-hour video game practice in a computer lab. The goal of the experimental study was to examine the effects of action video gaming on students' mathematics performance and mathematics anxiety as mediated by the effect of attention…

  13. BWID System Design Study

    Energy Technology Data Exchange (ETDEWEB)

    O' Brien, M.C.; Rudin, M.J.; Morrison, J.L.; Richardson, J.G.

    1991-01-01

    The mission of the Buried Waste Integrated Demonstration (BWID) System Design Study is to identify and evaluate technology process options for the cradle-to-grave remediation of Transuranic (TRU)-Contaminated Waste Pits and Trenches buried at the Idaho National Engineering Laboratory (INEL). Emphasis is placed upon evaluating system configuration options and associated functional and operational requirements for retrieving and treating the buried wastes. A Performance-Based Technology Selection Filter was developed to evaluate the identified remediation systems and their enabling technologies based upon system requirements and quantification of technical Comprehensive Environmental Response, Compensation, and Liability (CERCLA) balancing criteria. Remediation systems will also be evaluated with respect to regulatory and institutional acceptance and cost-effectiveness.

  14. BWID System Design Study

    Energy Technology Data Exchange (ETDEWEB)

    O`Brien, M.C.; Rudin, M.J.; Morrison, J.L.; Richardson, J.G.

    1991-12-31

    The mission of the Buried Waste Integrated Demonstration (BWID) System Design Study is to identify and evaluate technology process options for the cradle-to-grave remediation of Transuranic (TRU)-Contaminated Waste Pits and Trenches buried at the Idaho National Engineering Laboratory (INEL). Emphasis is placed upon evaluating system configuration options and associated functional and operational requirements for retrieving and treating the buried wastes. A Performance-Based Technology Selection Filter was developed to evaluate the identified remediation systems and their enabling technologies based upon system requirements and quantification of technical Comprehensive Environmental Response, Compensation, and Liability (CERCLA) balancing criteria. Remediation systems will also be evaluated with respect to regulatory and institutional acceptance and cost-effectiveness.

  15. Effect of medication reconciliation on unintentional medication discrepancies in acute hospital admissions of elderly adults: A multicenter study

    NARCIS (Netherlands)

    Bemt, P.M.L.A. van den; Schrieck-De Loos, E.M. van der; Linden, C. van der; Theeuwes, A.M.L.J.; Pol, A.G.

    2013-01-01

    Objectives To investigate the effect of pharmacy-based medication reconciliation on the frequency of unintentional medication discrepancies in acutely admitted individuals aged 65 and older. Design Multicenter intervention study with pre-post design. Setting Twelve Dutch hospitals. Participants One

  16. Visual daily functioning of chronic stroke patients assessed by goal attainment scaling after visual restorative training: an explorative study

    NARCIS (Netherlands)

    Bergsma, D.P.; Baars-Elsinga, A.; Sibbel, J.; Lubbers, P.; Visser-Meily, A.J.M.A.

    2014-01-01

    OBJECTIVE: To determine visual training effects on measures of daily life activities in cerebral blindness patients. METHOD: The study design was an explorative pre-post test design of patients in the chronic phase of stroke (not greater-than8 months) with visual field defects. Twelve hemianopic pat

  17. Effect of medication reconciliation on unintentional medication discrepancies in acute hospital admissions of elderly adults: A multicenter study

    NARCIS (Netherlands)

    Bemt, P.M.L.A. van den; Schrieck-De Loos, E.M. van der; Linden, C. van der; Theeuwes, A.M.L.J.; Pol, A.G.

    2013-01-01

    Objectives To investigate the effect of pharmacy-based medication reconciliation on the frequency of unintentional medication discrepancies in acutely admitted individuals aged 65 and older. Design Multicenter intervention study with pre-post design. Setting Twelve Dutch hospitals. Participants One

  18. Thermionic Reactor Design Studies

    Energy Technology Data Exchange (ETDEWEB)

    Schock, Alfred

    1994-06-01

    During the 1960's and early 70's the author performed extensive design studies, analyses, and tests aimed at thermionic reactor concepts that differed significantly from those pursued by other investigators. Those studies, like most others under Atomic Energy Commission (AEC and DOE) and the National Aeronautics and Space Administration (NASA) sponsorship, were terminated in the early 1970's. Some of this work was previously published, but much of it was never made available in the open literature. U.S. interest in thermionic reactors resumed in the early 80's, and was greatly intensified by reports about Soviet ground and flight tests in the late 80's. This recent interest resulted in renewed U.S. thermionic reactor development programs, primarily under Department of Defense (DOD) and Department of Energy (DOE) sponsorship. Since most current investigators have not had an opportunity to study all of the author's previous work, a review of the highlights of that work may be of value to them. The present paper describes some of the author's conceptual designs and their rationale, and the special analytical techniques developed to analyze their performance. The basic designs, first published in 1963, are based on single-cell converters, either double-ended diodes extending over the full height of the reactor core or single-ended diodes extending over half the core height. In that respect they are similar to the thermionic fuel elements employed in the Topaz-2 reactor subsequently developed in the Soviet Union, copies of which were recently imported by the U.S. As in the Topaz-2 case, electrically heated steady-state performance tests of the converters are possible before fueling. Where the author's concepts differed from the later Topaz-2 design was in the relative location of the emitter and the collector. Placing the fueled emitter on the outside of the cylindrical diodes permits much higher axial conductances to reduce ohmic

  19. Archaeological remote sensing application pre-post war situation of Babylon archaeological site—Iraq

    Science.gov (United States)

    Jahjah, Munzer; Ulivieri, Carlo; Invernizzi, Antonio; Parapetti, Roberto

    2007-06-01

    The first basic step in obtaining a correct geographical knowledge and initiative for archaeological cartography analysis is an adequately geo-localized representation of natural and semi-natural resources and human activities, present and past. In this context, the correct and contextual evaluation of the resources through the use of integrated techniques of aerial photos, remote sensing and geographic information system (GIS) supply the synoptic instrument to the real knowledge of the land geography and for the operational management of any research and project. We will describe, at a synthetic level, the maturity of the land systematic study of Babylon archaeological site using different change detection analysis. Topographic maps of 1920 and 1980 were used, 18 aerial photos (1986) were mosaicked and georeferenced, vector information was digitized and inserted in a GIS system, DTM was build. Object oriented image analysis activity is being carried on and initial results are available through a WebGIS. The use of remote sensing (Quickbird and Ikonos) data allows us to capture the integral mutations due to human interventions. Earth observation data and GIS system were an optimal starting point for generating and updating the cartography. This results will be indispensable for the Iraqi authority and scientific community who care about the future of the territory.

  20. Mentoring highly aggressive children: pre-post changes in mentors' attitudes, personality, and attachment tendencies.

    Science.gov (United States)

    Faith, Melissa A; Fiala, Samuel E; Cavell, Timothy A; Hughes, Jan N

    2011-12-01

    This study examined the degree to which mentoring highly aggressive children was associated with changes in mentors' attitudes, personality, and attachment tendencies. Participants were 102 college students who each mentored an aggressive, high-risk child across three academic semesters (spring, fall, spring). We examined pre- to post-mentoring changes in attitudes about mentoring efficacy and future parenting, Big Five personality characteristics, and attachment tendencies. Mentors also rated the impact of the mentoring relationship in their lives, and both mentors and mentees rated support of the mentoring relationship. Results indicated a statistically significant decrease over time in mentors' ratings of self-efficacy, openness, conscientiousness, extraversion, and agreeableness. These findings held even when controlling for ratings of relationship impact. However, mentors who rated the mentoring relationship as supportive tended to experience increased openness, conscientiousness, and agreeableness and less attachment-related avoidance over time. Child-rated support negatively predicted mentors' post-mentoring attitudes toward future parenting. Discussed are the potential costs of mentoring highly aggressive children and strategies that could help increase benefits to mentors.

  1. Addiction Studies: Exploring Students' Attitudes toward Research in a Graduate Program

    Science.gov (United States)

    James, Raven; Simons, Lori

    2011-01-01

    An exploratory study was conducted to compare addiction studies and community counseling students' attitudes toward research. A survey of 66 addiction studies and 17 community counseling students in graduate programs was used to explore interest and self-efficacy in research and the research training environment. A pre/post test design was used to…

  2. Student Achievement Outcomes Comprehensive School Reform: A Canadian Case Study

    Science.gov (United States)

    Ross, John A.; Scott, Garth; Sibbald, Timothy M.

    2012-01-01

    The authors conducted a third-party study of the student achievement effects of Struggling Schools, a user-generated approach to Comprehensive School Reform (CSR). The design was a quasiexperimental, pre-post matched sample (N = 180) with school as unit of analysis, drawing on 3 years of achievement data from standardized external assessments.…

  3. Studies in Interior Design

    Science.gov (United States)

    Environ Planning Design, 1970

    1970-01-01

    Floor plans and photographs illustrate a description of the Samuel C. Williams Library at Stevens Institute of Technology, Hoboken, N.J. The unusual interior design allows students to take full advantage of the library's resources. (JW)

  4. Studies in Interior Design

    Science.gov (United States)

    Environ Planning Design, 1970

    1970-01-01

    Floor plans and photographs illustrate a description of the Samuel C. Williams Library at Stevens Institute of Technology, Hoboken, N.J. The unusual interior design allows students to take full advantage of the library's resources. (JW)

  5. Increasing Interest in Social Studies: Social Perspective Taking and Self-Efficacy in Stimulating Simulations

    Science.gov (United States)

    Gehlbach, Hunter; Brown, Scott W.; Ioannou, Andri; Boyer, Mark A.; Hudson, Natalie; Niv-Solomon, Anat; Maneggia, Donalyn; Janik, Laura

    2008-01-01

    This study examined the potential of simulations to bolster interest in middle school social studies classrooms. Using a pre-post-design, we examined 305 middle school students (49% female) who participated in the web-based "GlobalEd" simulation. In contrast to the motivation declines middle school students usually experience, participants in this…

  6. Impact on Intercultural Competence When Studying Abroad and the Moderating Role of Personality

    Science.gov (United States)

    Ramirez R., Enrique

    2016-01-01

    The purpose of this study is to assess how studying abroad impacts the development of intercultural competence and the moderating role of student's personality. This research uses a pre-post design with a sample of 264 undergraduate students from four Colombian universities; it includes a group of students who participated in a one semester…

  7. Architecture as Design Study.

    Science.gov (United States)

    Kauppinen, Heta

    1989-01-01

    Explores the use of analogies in architectural design, the importance of Gestalt theory and aesthetic cannons in understanding and being sensitive to architecture. Emphasizes the variation between public and professional appreciation of architecture. Notes that an understanding of architectural process enables students to improve the aesthetic…

  8. Design of the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS).

    Science.gov (United States)

    Kessler, Ronald C; Colpe, Lisa J; Fullerton, Carol S; Gebler, Nancy; Naifeh, James A; Nock, Matthew K; Sampson, Nancy A; Schoenbaum, Michael; Zaslavsky, Alan M; Stein, Murray B; Ursano, Robert J; Heeringa, Steven G

    2013-12-01

    The Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS) is a multi-component epidemiological and neurobiological study designed to generate actionable evidence-based recommendations to reduce US Army suicides and increase basic knowledge about the determinants of suicidality. This report presents an overview of the designs of the six components of the Army STARRS. These include: an integrated analysis of the Historical Administrative Data Study (HADS) designed to provide data on significant administrative predictors of suicides among the more than 1.6 million soldiers on active duty in 2004-2009; retrospective case-control studies of suicide attempts and fatalities; separate large-scale cross-sectional studies of new soldiers (i.e. those just beginning Basic Combat Training [BCT], who completed self-administered questionnaires [SAQs] and neurocognitive tests and provided blood samples) and soldiers exclusive of those in BCT (who completed SAQs); a pre-post deployment study of soldiers in three Brigade Combat Teams about to deploy to Afghanistan (who completed SAQs and provided blood samples) followed multiple times after returning from deployment; and a platform for following up Army STARRS participants who have returned to civilian life. Department of Defense/Army administrative data records are linked with SAQ data to examine prospective associations between self-reports and subsequent suicidality. The presentation closes with a discussion of the methodological advantages of cross-component coordination.

  9. A pre-post test evaluation of the impact of the PELICAN MDT-TME Development Programme on the working lives of colorectal cancer team members

    Science.gov (United States)

    2010-01-01

    Background The PELICAN Multidisciplinary Team Total Mesorectal Excision (MDT-TME) Development Programme aimed to improve clinical outcomes for rectal cancer by educating colorectal cancer teams in precision surgery and related aspects of multidisciplinary care. The Programme reached almost all colorectal cancer teams across England. We took the opportunity to assess the impact of participating in this novel team-based Development Programme on the working lives of colorectal cancer team members. Methods The impact of participating in the programme on team members' self-reported job stress, job satisfaction and team performance was assessed in a pre-post course study. 333/568 (59%) team members, from the 75 multidisciplinary teams who attended the final year of the Programme, completed questionnaires pre-course, and 6-8 weeks post-course. Results Across all team members, the main sources of job satisfaction related to working in multidisciplinary teams; whilst feeling overloaded was the main source of job stress. Surgeons and clinical nurse specialists reported higher levels of job satisfaction than team members who do not provide direct patient care, whilst MDT coordinators reported the lowest levels of job satisfaction and job stress. Both job stress and satisfaction decreased after participating in the Programme for all team members. There was a small improvement in team performance. Conclusions Participation in the Development Programme had a mixed impact on the working lives of team members in the immediate aftermath of attending. The decrease in team members' job stress may reflect the improved knowledge and skills conferred by the Programme. The decrease in job satisfaction may be the consequence of being unable to apply these skills immediately in clinical practice because of a lack of required infrastructure and/or equipment. In addition, whilst the Programme raised awareness of the challenges of teamworking, a greater focus on tackling these issues may have

  10. Thermionic Reactor Design Studies

    Energy Technology Data Exchange (ETDEWEB)

    Schock, Alfred

    1994-08-01

    Paper presented at the 29th IECEC in Monterey, CA in August 1994. The present paper describes some of the author's conceptual designs and their rationale, and the special analytical techniques developed to analyze their (thermionic reactor) performance. The basic designs, first published in 1963, are based on single-cell converters, either double-ended diodes extending over the full height of the reactor core or single-ended diodes extending over half the core height. In that respect they are similar to the thermionic fuel elements employed in the Topaz-2 reactor subsequently developed in the Soviet Union, copies of which were recently imported by the U.S. As in the Topaz-2 case, electrically heated steady-state performance tests of the converters are possible before fueling.

  11. Efficiency of a Care Coordination Model: A Randomized Study with Stroke Patients

    Science.gov (United States)

    Claiborne, Nancy

    2006-01-01

    Objectives: This study investigated the efficiency of a social work care coordination model for stroke patients. Care coordination addresses patient care and treatment resources across the health care system to reduce risk, improve clinical outcomes, and maximize efficiency. Method: A randomly assigned, pre-post experimental design measured…

  12. Designing verbal autopsy studies

    Directory of Open Access Journals (Sweden)

    Shibuya Kenji

    2010-06-01

    Full Text Available Abstract Background Verbal autopsy analyses are widely used for estimating cause-specific mortality rates (CSMR in the vast majority of the world without high-quality medical death registration. Verbal autopsies -- survey interviews with the caretakers of imminent decedents -- stand in for medical examinations or physical autopsies, which are infeasible or culturally prohibited. Methods and Findings We introduce methods, simulations, and interpretations that can improve the design of automated, data-derived estimates of CSMRs, building on a new approach by King and Lu (2008. Our results generate advice for choosing symptom questions and sample sizes that is easier to satisfy than existing practices. For example, most prior effort has been devoted to searching for symptoms with high sensitivity and specificity, which has rarely if ever succeeded with multiple causes of death. In contrast, our approach makes this search irrelevant because it can produce unbiased estimates even with symptoms that have very low sensitivity and specificity. In addition, the new method is optimized for survey questions caretakers can easily answer rather than questions physicians would ask themselves. We also offer an automated method of weeding out biased symptom questions and advice on how to choose the number of causes of death, symptom questions to ask, and observations to collect, among others. Conclusions With the advice offered here, researchers should be able to design verbal autopsy surveys and conduct analyses with greatly reduced statistical biases and research costs.

  13. Study design in causal models

    OpenAIRE

    2012-01-01

    The causal assumptions, the study design and the data are the elements required for scientific inference in empirical research. The research is adequately communicated only if all of these elements and their relations are described precisely. Causal models with design describe the study design and the missing data mechanism together with the causal structure and allow the direct application of causal calculus in the estimation of the causal effects. The flow of the study is visualized by orde...

  14. Training Inservice Teachers' Competencies in Classroom Management. A Quasi-Experimental Study with Teachers of Secondary Schools

    Science.gov (United States)

    Piwowar, Valentina; Thiel, Felicitas; Ophardt, Diemut

    2013-01-01

    The current study evaluated the effectiveness of a training program for inservice secondary school teachers in classroom management. In a non-randomized pre-post-design, 19 teachers participated in a newly developed training (the intervention group) and 18 teachers participated in a control training (the control group). All participants reported…

  15. Training Inservice Teachers' Competencies in Classroom Management. A Quasi-Experimental Study with Teachers of Secondary Schools

    Science.gov (United States)

    Piwowar, Valentina; Thiel, Felicitas; Ophardt, Diemut

    2013-01-01

    The current study evaluated the effectiveness of a training program for inservice secondary school teachers in classroom management. In a non-randomized pre-post-design, 19 teachers participated in a newly developed training (the intervention group) and 18 teachers participated in a control training (the control group). All participants reported…

  16. Impact of emerging health insurance arrangements on diabetes outcomes and disparities: rationale and study design.

    Science.gov (United States)

    Wharam, J Frank; Soumerai, Steve; Trinacty, Connie; Eggleston, Emma; Zhang, Fang; LeCates, Robert; Canning, Claire; Ross-Degnan, Dennis

    2013-01-01

    Consumer-directed health plans combine lower premiums with high annual deductibles, Internet-based quality-of-care information, and health savings mechanisms. These plans may encourage members to seek better value for health expenditures but may also decrease essential care. The expansion of high-deductible health plans (HDHPs) represents a natural experiment of tremendous proportion. We designed a pre-post, longitudinal, quasi-experimental study to determine the effect of HDHPs on diabetes quality of care, outcomes, and disparities. We will use a 13-year rolling sample (2001-2013) of members of an HDHP and members of a control group. To reduce selection bias, we will limit participants to those whose employers mandate a single health insurance type. The study will measure rates of monthly hemoglobin A1c, lipid, and albuminuria testing; availability of blood glucose test strips; and rates of retinal examinations, high-severity emergency department visits, and preventable hospitalizations. Results could be used to design health plan features that promote high-quality care and better outcomes among people who have diabetes.

  17. Delineation of spall zone from pre/post shot reflections studies: Preliminary results from BEXAR. Los Alamos Source Region Project

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, S.R.; Cogbill, A.H.; Weaver, T.A. [Los Alamos National Lab., NM (United States); Miller, R.; Steeples, D. [Kansas Univ., Lawrence, KS (United States)

    1992-12-31

    In order to delineate the lateral and depth extent of spall from a buried nuclear explosion, we have performed a high-resolution pre- and post-shot seismic reflection survey from BEXAR. Although the data quality were marginal due to poor wave propagation through the volcanic tuffs of Pahute Mesa, a number of interesting differences are observed on the pre- and post-shot surveys. On the pre-shot survey, a reflector (reflector `` 1 ``) is observed at 250 ms (or about 150 m depth) using a stacking velocity of 1300 m/s. On the post-shot survey two reflectors are observed and a stacking velocity of 1150 m/s was used representing a 12% reduction in compressional velocity. With this stacking velocity, reflector `` 1 `` is recorded at 290 ms (still at about 150 m depth) and a new reflector ``2`` is observed at 210 ms (or about 100 m depth). These stacking velocities correspond well with available uphole travel times collected in U19ba and nearby U19ax (BEXAR and KEARSARGE emplacement holes, respectively). The cause for the differences observed in the pre- and post-shot surveys may be due to one of two reasons. First, it is possible that the near-surface rocks were damaged as part of the spallation process (thus reducing the in situ velocities) and reflector ``2`` represents a spall detachment surface. However, analysis of acceleration data collected close to the reflection line suggests that the ground motions were probably inadequate to damage the tuffs. Also, no evidence of actual spallation was actually observed. The second hypothesis is that the near-surface velocities of the tuffs were altered by the change in saturation state due to extensive rains occurring between the pre- and postshot surveys. Although the dependence of seismic velocity on saturation state is controlled by a number of complex factors, it cannot be ruled out.

  18. Visual Design Principles: An Empirical Study of Design Lore

    Science.gov (United States)

    Kimball, Miles A.

    2013-01-01

    Many books, designers, and design educators talk about visual design principles such as balance, contrast, and alignment, but with little consistency. This study uses empirical methods to explore the lore surrounding design principles. The study took the form of two stages: a quantitative literature review to determine what design principles are…

  19. Visual Design Principles: An Empirical Study of Design Lore

    Science.gov (United States)

    Kimball, Miles A.

    2013-01-01

    Many books, designers, and design educators talk about visual design principles such as balance, contrast, and alignment, but with little consistency. This study uses empirical methods to explore the lore surrounding design principles. The study took the form of two stages: a quantitative literature review to determine what design principles are…

  20. Structural Studies of Metalloprotein Design

    Science.gov (United States)

    2007-11-02

    TITLE AND SUBTITLE Structural Studies of Metalloprotein Design 6. AUTHOR(S) David W. Christianson 5. FUNDING NUMBERS N00014-96-1-0288 7...0288 PRINCIPAL INVESTIGATOR: David W. Christiansen INSTITUTION: University of Pennsylvania GRANT TITLE: Structural Studies of Metalloprotein

  1. Initial Development and Pilot Study Design of Interactive Lecture Demonstrations for ASTRO 101

    Science.gov (United States)

    Schwortz, Andria C.; French, D. A; Gutierrez, Joseph V; Sanchez, Richard L; Slater, Timothy F.; Tatge, Coty

    2014-06-01

    Interactive lecture demonstrations (ILDs) have repeatedly shown to be effective tools for improving student achievement in the context of learning physics. As a first step toward systematic development of interactive lecture demonstrations in ASTRO 101, the introductory astronomy survey course, a systematic review of education research, describing educational computer simulations (ECSs) reveals that initial development requires a targeted study of how ASTRO 101 students respond to ECSs in the non-science majoring undergraduate lecture setting. In this project we have adopted the process by which ILDs were designed, pilot-tested, and successfully implemented in the context of physics teaching (Sokoloff & Thornton, 1997; Sokoloff & Thornton, 2004). We have designed the initial pilot-test set of ASTRO 101 ILD instructional materials relying heavily on ECSs. Both an instructor’s manual and a preliminary classroom-ready student workbook have been developed, and we are implementing a pilot study to explore their effectiveness in communicating scientific content, and the extent to which they might enhance students’ knowledge of and perception about astronomy and science in general. The study design uses a pre-/post-test quasi-experimental study design measuring students’ normalized gain scores, calculated as per Hake (1998) and Prather (2009), using a slightly modified version of S. Slater’s (2011) Test Of Astronomy STandards TOAST combined with other instruments. The results of this initial study will guide the iterative development of ASTRO 101 ILDs that are intended to both be effective at enhancing student achievement and easy for instructors to successfully implement.

  2. Multimission Aircraft Design Study, Payload

    Science.gov (United States)

    2003-03-01

    iterated several times up to the level time allowed. 1.4 Scope It is necessary to recall that the backgrounds of the Systems Engineering Design Team...landing options are as wheels, skids, parachutes, airbags and none; that is, letting it fly forever or crash. Trade studies should be done in order to

  3. Design Evolution Study - Aging Options

    Energy Technology Data Exchange (ETDEWEB)

    P. McDaniel

    2002-04-05

    The purpose of this study is to identify options and issues for aging commercial spent nuclear fuel received for disposal at the Yucca Mountain Mined Geologic Repository. Some early shipments of commercial spent nuclear fuel to the repository may be received with high-heat-output (younger) fuel assemblies that will need to be managed to meet thermal goals for emplacement. The capability to age as much as 40,000 metric tons of heavy metal of commercial spent nuclear he1 would provide more flexibility in the design to manage this younger fuel and to decouple waste receipt and waste emplacement. The following potential aging location options are evaluated: (1) Surface aging at four locations near the North Portal; (2) Subsurface aging in the permanent emplacement drifts; and (3) Subsurface aging in a new subsurface area. The following aging container options are evaluated: (1) Complete Waste Package; (2) Stainless Steel inner liner of the waste package; (3) Dual Purpose Canisters; (4) Multi-Purpose Canisters; and (5) New disposable canister for uncanistered commercial spent nuclear fuel. Each option is compared to a ''Base Case,'' which is the expected normal waste packaging process without aging. A Value Engineering approach is used to score each option against nine technical criteria and rank the options. Open issues with each of the options and suggested future actions are also presented. Costs for aging containers and aging locations are evaluated separately. Capital costs are developed for direct costs and distributable field costs. To the extent practical, unit costs are presented. Indirect costs, operating costs, and total system life cycle costs will be evaluated outside of this study. Three recommendations for aging commercial spent nuclear fuel--subsurface, surface, and combined surface and subsurface are presented for further review in the overall design re-evaluation effort. Options that were evaluated but not recommended are

  4. [Saarland Growth Study: sampling design].

    Science.gov (United States)

    Danker-Hopfe, H; Zabransky, S

    2000-01-01

    The use of reference data to evaluate the physical development of children and adolescents is part of the daily routine in the paediatric ambulance. The construction of such reference data is based on the collection of extensive reference data. There are different kinds of reference data: cross sectional references, which are based on data collected from a big representative cross-sectional sample of the population, longitudinal references, which are based on follow-up surveys of usually smaller samples of individuals from birth to maturity, and mixed longitudinal references, which are a combination of longitudinal and cross-sectional reference data. The advantages and disadvantages of the different methods of data collection and the resulting reference data are discussed. The Saarland Growth Study was conducted for several reasons: growth processes are subject to secular changes, there are no specific reference data for children and adolescents from this part of the country and the growth charts in use in the paediatric praxis are possibly not appropriate any more. Therefore, the Saarland Growth Study served two purposes a) to create actual regional reference data and b) to create a database for future studies on secular trends in growth processes of children and adolescents from Saarland. The present contribution focusses on general remarks on the sampling design of (cross-sectional) growth surveys and its inferences for the design of the present study.

  5. AEROSOL PARTICLE COLLECTOR DESIGN STUDY

    Energy Technology Data Exchange (ETDEWEB)

    Lee, S; Richard Dimenna, R

    2007-09-27

    A computational evaluation of a particle collector design was performed to evaluate the behavior of aerosol particles in a fast flowing gas stream. The objective of the work was to improve the collection efficiency of the device while maintaining a minimum specified air throughput, nominal collector size, and minimal power requirements. The impact of a range of parameters was considered subject to constraints on gas flow rate, overall collector dimensions, and power limitations. Potential improvements were identified, some of which have already been implemented. Other more complex changes were identified and are described here for further consideration. In addition, fruitful areas for further study are proposed.

  6. Design and Co-design of Project-organized Studies

    DEFF Research Database (Denmark)

    Nielsen, Jørgen Lerche; Andreasen, Lars Birch

    2014-01-01

    The chapter contributes to discussions on design processes in relation to education, presenting different notions of design research and demonstrating how professors and students are involved together in designing innovative and constructive study processes that can help foster students' engageme......, self-awareness, mutual evaluation, reflection, and critical and creative thinking.......The chapter contributes to discussions on design processes in relation to education, presenting different notions of design research and demonstrating how professors and students are involved together in designing innovative and constructive study processes that can help foster students' engagement...

  7. STUDI PEMANFAATAN DAN KEAMANAN KOMBINASI METFORMIN DENGAN EKSTRAK CAMPURAN ANDROGRAPHIS PANICULATADAN SYZYGIUM POLYANTHUM UNTUK PENGOBATAN DIABETES MELLITUS (PRELIMINARY STUDY)

    OpenAIRE

    Suharmiati Suharmiati; Betty Roosihermiatie

    2013-01-01

    ABSTRACT Background: Use of Andrographis paniculata and Syzigium polyanthum have been used widely, on the contrary the benefit and safety have not been scientifically proven. This study aimed to overview and analyze benefit and safety the extract of Andrographis paniculata and Syzigium polyanthum mixture to decrease blood glucose concentration. Methods: It was an experiment study among intervension and control groups by a block random sampling with pre-post test design. Data ...

  8. HTS Insert Magnet Design Study

    CERN Document Server

    Devaux, M; Fleiter, J; Fazilleau, P; Lécrevisse, T; Pes, C; Rey, J-M; Rifflet, J-M; Sorbi, M; Stenvall, A; Tixador, P; Volpini, G

    2011-01-01

    Future accelerator magnets will need to reach higher field in the range of 20 T. This field level is very difficult to reach using only Low Temperature Superconductor materials whereas High Temperature Superconductors (HTS) provide interesting opportunities. High current densities and stress levels are needed to design such magnets. YBCO superconductor indeed carries large current densities under high magnetic field and provides good mechanical properties especially when produced using the IBAD approach. The HFM EUCARD program studies the design and the realization of an HTS insert of 6 T inside a Nb3Sn dipole of 13T at 4.2 K. In the2HTS insert, engineering current densities higher than 250 MA/m under 19 T are required to fulfill the specifications. The stress level is also very severe. YBCO IBAD tapes theoretically meet these challenges from presented measurements. The insert protection is also a critical because HTS materials show low quench propagation velocities and the coupling with the Nb3Sn magnet make...

  9. Elementary Teachers' Beliefs about Teaching Science and Classroom Practice: An Examination of Pre/Post NCLB Testing in Science

    Science.gov (United States)

    Milner, Andrea R.; Sondergeld, Toni A.; Demir, Abdulkadir; Johnson, Carla C.; Czerniak, Charlene M.

    2012-01-01

    The impact of No Child Left Behind (NCLB) mandated state science assessment on elementary teachers' beliefs about teaching science and their classroom practice is relatively unknown. For many years, the teaching of science has been minimized in elementary schools in favor of more emphasis on reading and mathematics. This study examines the…

  10. Novel Compressor Blade Design Study

    Science.gov (United States)

    Srinivas, Abhay

    Jet engine efficiency goals are driving compressors to higher pressure ratios and engines to higher bypass ratios, each one driving to smaller cores. This is leading to larger tip gaps relative to the blade height. These larger relative tip clearances would negate some of the cycle improvements, and ways to mitigate this effect must be found. A novel split tip blade geometry has been created which helps improve the efficiency at large clearances while also improving operating range. Two identical blades are leaned in opposite directions starting at 85% span. They are cut at mid chord and the 2 halves then merged together so a split tip is created. The result is similar to the alula feathers on a soaring bird. The concept is that the split tip will energize the tip flow and increase range. For higher relative tip clearance, this will also improve efficiency. The 6th rotor of a highly loaded 10 stage machine was chosen as the baseline for this study. Three dimensional CFD simulations were performed using CD Adapco's Star-CCM+ at 5 clearances for the baseline and split tip geometry. The choking flow and stall margin of the split tip blade was higher than that of the baseline blade for all tip clearances. The pressure ratio of the novel blade was higher than that of the baseline blade near choke, but closer to stall it decreased. The sensitivity of peak efficiency to clearance was improved. At tight clearances of 0.62% of blade height, the maximum efficiency of the new design was less than the baseline blade, but as the tip clearance was increased above 2.5%, the maximum efficiency increased. Structural analysis was also performed to ascertain the feasibility of the design.

  11. Pre-Post Tornado Effects on Aggressive Children's Psychological and Behavioral Adjustment Through One-Year Postdisaster.

    Science.gov (United States)

    Lochman, John E; Vernberg, Eric; Powell, Nicole P; Boxmeyer, Caroline L; Jarrett, Matthew; McDonald, Kristina; Qu, Lixin; Hendrickson, Michelle; Kassing, Francesca

    2017-01-01

    Using a risk-resilience framework, this study examined how varying levels of exposure to a natural disaster (EF-4 tornado) and children's characteristics (sex; anxiety) influenced the behavioral and psychological adjustment of children who shared a common risk factor predisaster (elevated aggression) prior to exposure through 1-year postdisaster. Participants included 360 children in Grades 4-6 (65% male; 78% African American) and their parents from predominantly low-income households who were already participating in a longitudinal study of indicated prevention effects for externalizing outcomes when the tornado occurred in 2011. Fourth-grade children who were screened for overt aggressive behavior were recruited in 3 annual cohorts (120 per year, beginning in 2009). Parent-rated aggression and internalizing problems were assessed prior to the tornado (Wave 1), within a half-year after the tornado (Wave 2), and at a 1-year follow-up (Wave 3). Children and parents rated their exposure to aspects of tornado-related traumatic experiences at Wave 3. Children displayed less reduction on aggression and internalizing problems if the children had experienced distress after the tornado or fears for their life, in combination with their pre-tornado level of anxiety. Higher levels of children's and parents' exposure to the tornado interacted with children's lower baseline child anxiety to predict less reduction in aggression and internalizing problems 1 year after the tornado. Higher levels of disaster exposure negatively affected at-risk children's level of improvement in aggression and internalizing problems, when life threat (parent- and child-reported) and child-reported distress after the tornado were moderated by baseline anxiety.

  12. Impact of vaccine economic programs on physician referral of children to public vaccine clinics: a pre-post comparison

    Directory of Open Access Journals (Sweden)

    Troy Judith A

    2006-01-01

    Full Text Available Abstract Background The Vaccines for Children (VFC Program is a major vaccine entitlement program with limited long-term evaluation. The objectives of this study are to evaluate the effect of VFC on physician reported referral of children to public health clinics and on doses administered in the public sector. Methods Minnesota and Pennsylvania primary care physicians (n = 164, completed surveys before (e.g., 1993 and after (2003 VFC, rating their likelihood on a scale of 0 (very unlikely to 10 (very likely of referring a child to the health department for immunization. Results The percentage of respondents likely to refer was 60% for an uninsured child, 14% for a child with Medicaid, and 3% for a child with insurance that pays for immunization. Half (55% of the physicians who did not participate in VFC were likely to refer a Medicaid-insured child, as compared with 6% of those who participated (P P P = 0.001. Conclusion Reported out-referral to public clinics decreased over time. In light of increasing immunizations rates, this suggests that more vaccines were being administered in private provider offices.

  13. ACSA: Conference book: Design Studies

    NARCIS (Netherlands)

    Van Duin, L.

    1992-01-01

    In recent years, the Faculty of Architecture, Housing, Urban Design and Planning has been undergoing large changes in the training and research program mes. These changes followon from the signals received from professional practice, but above all from the desire of staff and students to design prog

  14. Motor imagery training for children with developmental coordination disorder: Study protocol for a randomized controlled trial

    OpenAIRE

    2016-01-01

    Background Previous studies have shown that the predictive control of movements is impaired in children with Developmental Coordination Disorder (DCD), most likely due to a deficit in the internal modeling of movements. Motor imagery paradigms have been used to test this internal modeling deficit. The aim of the present study is to examine whether a training focused on the mental imagery of motor skills, can help to improve the motor abilities of children with DCD. Methods/Design A pre-post d...

  15. Pulsed DEMO design assessment studies

    CERN Document Server

    Todd, T N

    2013-01-01

    Now that ITER is under construction, interest is increasing in the specification and design of the successor machine, a Demonstration Power Plant (DEMO), which in Europe is coordinated by the EFDA Power Plant Physics and Technology programme. This paper summarises the work carried out for EFDA in 2011-2012 on design issues pertinent to a pulsed version of DEMO, intended to be implemented with little or no extrapolation of technology available today. The work was carried out by the Euratom Fusion Associations CCFE, CEA, CRPP, ENEA and KIT, and in addition to a review of recent relevant literature addressed systems code analyses (pulse length vs. size), erosion of plasma facing components, thermomechanical fatigue in the blanket and first wall, a range of energy storage issues, and fatigue life improvements in Nb3Sn CICC superconductors.

  16. Salud mental en reclusos: un análisis pre-post intervención psicosocial con grupo control de comparación

    Directory of Open Access Journals (Sweden)

    Miguel Jesús Bascón Díaz

    Full Text Available La literatura científica advierte de la elevada presencia de trastornos mentales en el medio penitenciario. Por ello, en este trabajo nos planteamos evaluar la salud psicosocial y la autorregulación de reclusos en relación a un grupo control de participantes no reclusos; adicionalmente tratamos de conocer la incidencia de la variable tiempo de reclusión y analizar el efecto intragrupo pre-post entrenamiento en habilidades sociales y comunicativas. La muestra estuvo compuesta por 20 varones, 10 reclusos (cinco con más de un año de condena y cinco con menos y 10 participantes sin antecedentes delictivos, a los que se les administró el cuestionario de salud GHQ-28 y la escala de autorregulación MAPA. Se aplicó la prueba no paramétrica Mann-Whitney (U para el cálculo de probabilidades y el test de Cramer (V como indicador del tamaño de efecto. Los resultados indicaron que la reclusión no implicó necesariamente peor salud y autorregulación, que el tiempo de condena no ejerció excesiva influencia sobre estas dos dimensiones y que el taller de habilidades sociales no pareció, según el análisis pre-postest, haber producido efectos sobre la salud y la autorregulación de los reclusos. Finalmente, se discuten algunas reflexiones generales así como nuevas propuestas para mejorar actuaciones futuras.

  17. Selecting the appropriate study design for your research: Descriptive study designs

    OpenAIRE

    Aamir Omair

    2015-01-01

    This article describes the importance of selecting the appropriate epidemiological study design for a given study question. It provides an explanation to the different terms used in describing study designs with regards to observational versus interventional and descriptive versus analytical types of study designs. This article focuses on the description of the different types of descriptive study designs, that is, case report, case series, correlational, and cross-sectional study designs. Th...

  18. Study on Professional Process of Bra Design

    Institute of Scientific and Technical Information of China (English)

    李明菊; 徐朝晖

    2001-01-01

    The process of bra design in the underwear industry is studied. Several important aspects of the process were identified: sizing, fabric selection, pattern development and grading, the use of CAD system, fitting and wear trials. Although the design process relies heavily on the expertise and experience of designers, the modern technology such as CAD can facilitate and optimize the design process, and the fitting process on life models is essential for the underwear design. The differences between domestic underwear companies and foreign major ones mainly lie at the lack of dress form specially used for underwear design, lack of CAD/CAM or not making full use of them, and most of all, lack of the professional bra designers or even skillful pattern designers. The prospects and future model of bra design process were also elaborated in this paper.

  19. Spiral 2: preliminary design study

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-11-15

    The scientific council of GANIL asked to perform a comparative study on the production methods based on gamma induced fission and rapid-neutron induced fission concerning the nature and the intensity of the neutron-rich products. The production rate expected should be around 10{sup 13} fissions per second. The study should include the implantation and the costs of the concerned accelerators. The scientific committee recommended also to study the possibility to re-inject the radioactive beams of SPIRAL-II in the cyclotrons available at GANIL in order to give access to an energy range from 1.7 to 100 MeV/nucleon. For that purpose, some study groups have been formed to evaluate the possibility of such a project in the different components: physics case, target-ion sources, drivers, post-acceleration and general infrastructure. The organization of the project study is given at the end of this report. The following report presents an overview of the study. Particularly the total costs have been assessed according to 3 options for the driver: 38.0*10{sup 6} euros for a 40 MeV deuteron linac, 18.7*10{sup 6} euros for a 45 MeV electron linac, and 29.1*10{sup 6} euros for a 80 MeV deuteron cyclotron.

  20. Collective design in 3D printing: A large scale empirical study of designs, designers and evolution

    DEFF Research Database (Denmark)

    Özkil, Ali Gürcan

    2017-01-01

    This paper provides an empirical study of a collective design platform (Thingiverse); with the aim of understanding the phenomenon and investigating how designs concurrently evolve through the large and complex network of designers. The case study is based on the meta-data collected from 158 489 ...

  1. Interval Management Display Design Study

    Science.gov (United States)

    Baxley, Brian T.; Beyer, Timothy M.; Cooke, Stuart D.; Grant, Karlus A.

    2014-01-01

    In 2012, the Federal Aviation Administration (FAA) estimated that U.S. commercial air carriers moved 736.7 million passengers over 822.3 billion revenue-passenger miles. The FAA also forecasts, in that same report, an average annual increase in passenger traffic of 2.2 percent per year for the next 20 years, which approximates to one-and-a-half times the number of today's aircraft operations and passengers by the year 2033. If airspace capacity and throughput remain unchanged, then flight delays will increase, particularly at those airports already operating near or at capacity. Therefore it is critical to create new and improved technologies, communications, and procedures to be used by air traffic controllers and pilots. National Aeronautics and Space Administration (NASA), the FAA, and the aviation industry are working together to improve the efficiency of the National Airspace System and the cost to operate in it in several ways, one of which is through the creation of the Next Generation Air Transportation System (NextGen). NextGen is intended to provide airspace users with more precise information about traffic, routing, and weather, as well as improve the control mechanisms within the air traffic system. NASA's Air Traffic Management Technology Demonstration-1 (ATD-1) Project is designed to contribute to the goals of NextGen, and accomplishes this by integrating three NASA technologies to enable fuel-efficient arrival operations into high-density airports. The three NASA technologies and procedures combined in the ATD-1 concept are advanced arrival scheduling, controller decision support tools, and aircraft avionics to enable multiple time deconflicted and fuel efficient arrival streams in high-density terminal airspace.

  2. [Architecture and design of mental health institutions].

    Science.gov (United States)

    Richter, Dirk; Hoffmann, Holger

    2014-04-01

    The physical environment of mental health institutions is regarded as a therapeutic agent within the treatment. There is only little scientific evidence on the consequences of architecture and design on psychiatric patients available. A systematic review was conducted on studies from adult mental health institutions. 25 studies were included into the review. Pre-post-studies and control group conditions were predominant study designs. Randomized controlled trials were not available. Interventions reached from art installations up to entire ward renovations. Outcome indicators were rather heterogeneous, including psychopathology, behavioural observations and aggression incidents. Overwhelmingly, the studies revealed positive results of interventions into the physical environment. We found positive outcomes independent from the intervention in detail. This result should be interpreted in the light of the generally low study quality and further methodological problems. © Georg Thieme Verlag KG Stuttgart · New York.

  3. Effects of cervical mobilization and exercise on pain, movement and function in subjects with temporomandibular disorders: a single group pre-post test

    Science.gov (United States)

    CALIXTRE, Letícia Bojikian; GRÜNINGER, Bruno Leonardo da Silva; HAIK, Melina Nevoeiro; ALBURQUERQUE-SENDÍN, Francisco; OLIVEIRA, Ana Beatriz

    2016-01-01

    ABSTRACT Objective To investigate the effect of a rehabilitation program based on cervical mobilization and exercise on clinical signs and mandibular function in subjects with temporomandibular disorder (TMD). Material and Methods: Single-group pre-post test, with baseline comparison. Subjects Twelve women (22.08±2.23 years) with myofascial pain and mixed TMD according to the Research Diagnostic Criteria for Temporomandibular Disorders. Outcome measures Subjects were evaluated three times: twice before (baseline phase) and once after intervention. Self-reported pain, jaw function [according to the Mandibular Functional Impairment Questionnaire (MFIQ)], pain-free maximum mouth opening (MMO), and pressure pain thresholds (PPTs) of both masseter and temporalis muscles were obtained. Baseline and post-intervention differences were investigated, and effect size was estimated through Cohen’s d coefficient. Results Jaw function improved 7 points on the scale after the intervention (P=0.019), and self-reported pain was significantly reduced (P=0.009). Pain-free MMO varied from 32.3±8.8 mm to 38±8.8 mm and showed significant improvement (P=0.017) with moderate effect size when compared to the baseline phase. PPT also increased with moderate effect size, and subjects had the baseline values changed from 1.23±0.2 kg/cm2 to 1.4±0.2 kg/cm2 in the left masseter (P=0.03), from 1.31±0.28 kg/cm2 to 1.51±0.2 kg/cm2 in the right masseter (P>0.05), from 1.32±0.2 kg/cm2 to 1.46±0.2 kg/cm2 in the left temporalis (P=0.047), and from 1.4±0.2 kg/cm2 to 1.67±0.3 kg/cm2 in the right temporalis (P=0.06). Conclusions The protocol caused significant changes in pain-free MMO, self-reported pain, and functionality of the stomatognathic system in subjects with myofascial TMD, regardless of joint involvement. Even though these differences are statistically significant, their clinical relevance is still questionable. PMID:27383698

  4. Effects of cervical mobilization and exercise on pain, movement and function in subjects with temporomandibular disorders: a single group pre-post test

    Directory of Open Access Journals (Sweden)

    Letícia Bojikian CALIXTRE

    Full Text Available ABSTRACT Objective To investigate the effect of a rehabilitation program based on cervical mobilization and exercise on clinical signs and mandibular function in subjects with temporomandibular disorder (TMD. Material and Methods: Single-group pre-post test, with baseline comparison. Subjects Twelve women (22.08±2.23 years with myofascial pain and mixed TMD according to the Research Diagnostic Criteria for Temporomandibular Disorders. Outcome measures Subjects were evaluated three times: twice before (baseline phase and once after intervention. Self-reported pain, jaw function [according to the Mandibular Functional Impairment Questionnaire (MFIQ], pain-free maximum mouth opening (MMO, and pressure pain thresholds (PPTs of both masseter and temporalis muscles were obtained. Baseline and post-intervention differences were investigated, and effect size was estimated through Cohen’s d coefficient. Results Jaw function improved 7 points on the scale after the intervention (P=0.019, and self-reported pain was significantly reduced (P=0.009. Pain-free MMO varied from 32.3±8.8 mm to 38±8.8 mm and showed significant improvement (P=0.017 with moderate effect size when compared to the baseline phase. PPT also increased with moderate effect size, and subjects had the baseline values changed from 1.23±0.2 kg/cm2 to 1.4±0.2 kg/cm2 in the left masseter (P=0.03, from 1.31±0.28 kg/cm2 to 1.51±0.2 kg/cm2 in the right masseter (P>0.05, from 1.32±0.2 kg/cm2 to 1.46±0.2 kg/cm2 in the left temporalis (P=0.047, and from 1.4±0.2 kg/cm2 to 1.67±0.3 kg/cm2 in the right temporalis (P=0.06. Conclusions The protocol caused significant changes in pain-free MMO, self-reported pain, and functionality of the stomatognathic system in subjects with myofascial TMD, regardless of joint involvement. Even though these differences are statistically significant, their clinical relevance is still questionable.

  5. Assumption Trade-Offs When Choosing Identification Strategies for Pre-Post Treatment Effect Estimation: An Illustration of a Community-Based Intervention in Madagascar.

    Science.gov (United States)

    Weber, Ann M; van der Laan, Mark J; Petersen, Maya L

    2015-03-01

    Failure (or success) in finding a statistically significant effect of a large-scale intervention may be due to choices made in the evaluation. To highlight the potential limitations and pitfalls of some common identification strategies used for estimating causal effects of community-level interventions, we apply a roadmap for causal inference to a pre-post evaluation of a national nutrition program in Madagascar. Selection into the program was non-random and strongly associated with the pre-treatment (lagged) outcome. Using structural causal models (SCM), directed acyclic graphs (DAGs) and simulated data, we illustrate that an estimand with the outcome defined as the post-treatment outcome controls for confounding by the lagged outcome but not by possible unmeasured confounders. Two separate differencing estimands (of the pre- and post-treatment outcome) have the potential to adjust for a certain type of unmeasured confounding, but introduce bias if the additional identification assumptions they rely on are not met. In order to illustrate the practical impact of choice between three common identification strategies and their corresponding estimands, we used observational data from the community nutrition program in Madagascar to estimate each of these three estimands. Specifically, we estimated the average treatment effect of the program on the community mean nutritional status of children 5 years and under and found that the estimate based on the post-treatment estimand was about a quarter of the magnitude of either of the differencing estimands (0.066 SD vs. 0.26-0.27 SD increase in mean weight-for-age z-score). Choice of estimand clearly has important implications for the interpretation of the success of the program to improve nutritional status of young children. A careful appraisal of the assumptions underlying the causal model is imperative before committing to a statistical model and progressing to estimation. However, knowledge about the data

  6. Effects of cervical mobilization and exercise on pain, movement and function in subjects with temporomandibular disorders: a single group pre-post test.

    Science.gov (United States)

    Calixtre, Letícia Bojikian; Grüninger, Bruno Leonardo da Silva; Haik, Melina Nevoeiro; Alburquerque-Sendín, Francisco; Oliveira, Ana Beatriz

    2016-01-01

    To investigate the effect of a rehabilitation program based on cervical mobilization and exercise on clinical signs and mandibular function in subjects with temporomandibular disorder (TMD). Single-group pre-post test, with baseline comparison. Twelve women (22.08±2.23 years) with myofascial pain and mixed TMD according to the Research Diagnostic Criteria for Temporomandibular Disorders. Subjects were evaluated three times: twice before (baseline phase) and once after intervention. Self-reported pain, jaw function [according to the Mandibular Functional Impairment Questionnaire (MFIQ)], pain-free maximum mouth opening (MMO), and pressure pain thresholds (PPTs) of both masseter and temporalis muscles were obtained. Baseline and post-intervention differences were investigated, and effect size was estimated through Cohen's d coefficient. Jaw function improved 7 points on the scale after the intervention (P=0.019), and self-reported pain was significantly reduced (P=0.009). Pain-free MMO varied from 32.3±8.8 mm to 38±8.8 mm and showed significant improvement (P=0.017) with moderate effect size when compared to the baseline phase. PPT also increased with moderate effect size, and subjects had the baseline values changed from 1.23±0.2 kg/cm2 to 1.4±0.2 kg/cm2 in the left masseter (P=0.03), from 1.31±0.28 kg/cm2 to 1.51±0.2 kg/cm2 in the right masseter (P>0.05), from 1.32±0.2 kg/cm2 to 1.46±0.2 kg/cm2 in the left temporalis (P=0.047), and from 1.4±0.2 kg/cm2 to 1.67±0.3 kg/cm2 in the right temporalis (P=0.06). The protocol caused significant changes in pain-free MMO, self-reported pain, and functionality of the stomatognathic system in subjects with myofascial TMD, regardless of joint involvement. Even though these differences are statistically significant, their clinical relevance is still questionable.

  7. Increasing use of mental health services in remote areas using mobile technology: a pre-post evaluation of the SMART Mental Health project in rural India.

    Science.gov (United States)

    Maulik, Pallab K; Kallakuri, Sudha; Devarapalli, Siddhardha; Vadlamani, Vamsi Krishna; Jha, Vivekanand; Patel, Anushka

    2017-06-01

    About 25% of the Indian population experience common mental disorders (CMD) but only 15-25% of them receive any mental health care. Stigma, lack of adequate mental health professionals and mental health services account for this treatment gap, which is worse in rural areas. Our project evaluated task shifting and mobile-technology based electronic decision support systems to enhance the ability of primary care health workers to provide evidence-based mental health care for stress, depression, and suicidal risk in 30 remote villages in the state of Andhra Pradesh, India. The Systematic Medical Appraisal Referral and Treatment (SMART) Mental Health project between May 2014 and April 2016 trained lay village health workers (Accredited Social Health Activists - ASHAs) and primary care doctors to screen, diagnose and manage individuals with common mental disorders using an electronic decision support system. An anti-stigma campaign using multi-media approaches was conducted across the villages at the outset of the project. A pre-post evaluation using mixed methods assessed the change in mental health service utilization by screen positive individuals. This paper reports on the quantitative aspects of that evaluation. Training was imparted to 21 ASHAs and 2 primary care doctors. 5007 of 5167 eligible individuals were screened, and 238 were identified as being positive for common mental disorders and referred to the primary care doctors for further management. Out of them, 2 (0.8%) had previously utilized mental health services. During the intervention period, 30 (12.6%) visited the primary care doctor for further diagnosis and treatment, as advised. There was a significant reduction in the depression and anxiety scores between start and end of the intervention among those who had screened positive at the beginning. Stigma and mental health awareness in the broader community improved during the project. The intervention led to individuals being screened for common mental

  8. TLEP design study forges ahead

    CERN Multimedia

    Alain Blondel & Mike Koratzinos

    2013-01-01

    As the Future Circular Collider (FCC) study is launched, one of its component parts, TLEP, enjoys a successful workshop at CERN. The FCC study looks at all options for a future circular collider with the emphasis on a hadron machine with TLEP as a possible intermediate step.   The poster of the sixth TLEP workshop that took place at CERN. Japanese artist Kazuya Akimoto kindly agreed to the use of one of his works as the basis for the poster’s backdrop. October 16 to 18 saw a three-day workshop on TLEP, the sixth in the series. The workshop took place at CERN and was well attended, informative and stimulating. To name just one of the influential people present, Herwig Schopper, ex-Director General of CERN and instrumental in the approval, construction and success of LEP, was among the participants. But what exactly is TLEP? The name was, somehow serendipitously, coined from future lepton collider option studies and stands for triple-LEP, a machine three times the size of LEP. But th...

  9. Principles of study design in environmental epidemiology.

    OpenAIRE

    Morgenstern, H.; Thomas, D

    1993-01-01

    This paper discusses the principles of study design and related methodologic issues in environmental epidemiology. Emphasis is given to studies aimed at evaluating causal hypotheses regarding exposures to suspected health hazards. Following background sections on the quantitative objectives and methods of population-based research, we present the major types of observational designs used in environmental epidemiology: first, the three basic designs involving the individual as the unit of anal...

  10. Mobile Variable Depth Sampling System Design Study

    Energy Technology Data Exchange (ETDEWEB)

    BOGER, R.M.

    2000-08-25

    A design study is presented for a mobile, variable depth sampling system (MVDSS) that will support the treatment and immobilization of Hanford LAW and HLW. The sampler can be deployed in a 4-inch tank riser and has a design that is based on requirements identified in the Level 2 Specification (latest revision). The waste feed sequence for the MVDSS is based on Phase 1, Case 3S6 waste feed sequence. Technical information is also presented that supports the design study.

  11. Multi-Imagery Exploitation Configuration Design Study.

    Science.gov (United States)

    1982-11-01

    A124 88? MULTI-IMAGERY ENPLOITRTION CONFIGURATION DESIGN STUDY 1/2 (U) HARRIS CORP MEL8OURNE FL GOVERNMENT COMMUNICATION SYSTEMS DIV T E TIMOTHY ET...DESIGN STUDY 212 (U) HARRIS CORP MELBOURNE FL GOVERNMENT COMMUNICATION SYSTEMS DIV T E TIMOTHY ET AL. NOV 82 RRDC-TR-82-33 UNCLASSIFIED F31692-Si-C-8095 F

  12. On the design of satisfaction studies

    DEFF Research Database (Denmark)

    Kristensen, Kai; Eskildsen, Jacob Kjær

    2008-01-01

    In the effect sampling method, presentation of researcher, the intro text, the order of questions in the questionnaire along with the number of categories in the rating scale is tested in relation to the design of satisfaction studies. Based on the analyses specific recommendations for designing...... satisfaction studies are given....

  13. Design study for asteroidal exploitation

    Science.gov (United States)

    Adams, Carl; Blissit, Jim; Jarrett, Dave; Sanner, Rob; Yanagawa, Koji

    1985-08-01

    A systematic approach to asteroidal exploitation for the 1990 to 2010 time frame is presented as an initial step toward expanding the use of space beyond the space station by providing a source of lower cost materials. With only a limited amount of information known about the asteroids, reconnaissance and exploration phases to determine the exact locations and compositions of several earth-approaching asteroids are required. Earth-based telescopes are used to locate and study the asteroids, while unmanned probes will return samples of asteroidal material to earth for analysis. After these phases are completed, the retrieval of a 35,000 metric ton piece of the asteroid Anteros is undertaken. A cargo transporter uses magnetoplasmadynamic (MPD) arcjets outbound and a mass-driver using asteroidal material inbound. A crew ship uses ion engines. Low thrust trajectories are used for both spacecraft. A materials processing facility will manufacture propellant pellets and retrieve non-propellant materials for spacecraft use. The cost is 1/10th that to transport the same materials from earth to high earth orbit. The project will cost 25 percent less if done in conjunction with a lunar and Martian base.

  14. Statistical design and evaluation of biomarker studies.

    Science.gov (United States)

    Dobbin, Kevin K

    2014-01-01

    We review biostatistical aspects of biomarker studies, including design and analysis issues, covering the range of settings required for translational research-from early exploratory studies through clinical trials.

  15. Fusion reactor blanket/shield design study

    Energy Technology Data Exchange (ETDEWEB)

    Smith, D.L.; Clemmer, R.G.; Harkness, S.D.

    1979-07-01

    A joint study of tokamak reactor first-wall/blanket/shield technology was conducted by Argonne National Laboratory (ANL) and McDonnell Douglas Astronautics Company (MDAC). The objectives of this program were the identification of key technological limitations for various tritium-breeding-blanket design concepts, establishment of a basis for assessment and comparison of the design features of each concept, and development of optimized blanket designs. The approach used involved a review of previously proposed blanket designs, analysis of critical technological problems and design features associated with each of the blanket concepts, and a detailed evaluation of the most tractable design concepts. Tritium-breeding-blanket concepts were evaluated according to the proposed coolant. The ANL effort concentrated on evaluation of lithium- and water-cooled blanket designs while the MDAC effort focused on helium- and molten salt-cooled designs. A joint effort was undertaken to provide a consistent set of materials property data used for analysis of all blanket concepts. Generalized nuclear analysis of the tritium breeding performance, an analysis of tritium breeding requirements, and a first-wall stress analysis were conducted as part of the study. The impact of coolant selection on the mechanical design of a tokamak reactor was evaluated. Reference blanket designs utilizing the four candidate coolants are presented.

  16. Mirror Advanced Reactor Study interim design report

    Energy Technology Data Exchange (ETDEWEB)

    1983-04-01

    The status of the design of a tenth-of-a-kind commercial tandem-mirror fusion reactor is described at the midpoint of a two-year study. When completed, the design is to serve as a strategic goal for the mirror fusion program. The main objectives of the Mirror Advanced Reactor Study (MARS) are: (1) to design an attractive tandem-mirror fusion reactor producing electricity and synfuels (in alternate versions), (2) to identify key development and technology needs, and (3) to exploit the potential of fusion for safety, low activation, and simple disposal of radioactive waste. In the first year we have emphasized physics and engineering of the central cell and physics of the end cell. Design optimization and trade studies are continuing, and we expect additional modifications in the end cells to further improve the performance of the final design.

  17. Cryostat design case studies, principles and engineering

    CERN Document Server

    2016-01-01

    This book enables the reader to learn the fundamental and applied aspects of practical cryostat design by examining previous design choices and resulting cryostat performance. Through a series of extended case studies the book presents an overview of existing cryostat design covering a wide range of cryostat types and applications, including the magnet cryostats that comprise the majority of the Large Hadron Collider at CERN, space-borne cryostats containing sensors operating below 1 K, and large cryogenic liquid storage vessels. It starts with an introductory section on the principles of cryostat design including practical data and equations. This section is followed by a series of case studies on existing cryostats, describing the specific requirements of the cryostat, the challenges involved and the design choices made along with the resulting performance of the cryostat. The cryostat examples used in the studies are chosen to cover a broad range of cryostat applications and the authors of each case are ...

  18. User Assemblages in Design: An Ethnographic Study

    OpenAIRE

    2010-01-01

    This thesis presents an ethnographic study of the role of users in user-centered design. It is written from the perspective of science and technology studies, in particular developments in actor-network theory, and draws on the notion of the assemblage from the work of Deleuze and Guattari. The data for this thesis derives from a six-month field study of the routine discourse and practices of user-centered designers working for a multinational microprocessor manufacturer. The central argument...

  19. Mixed sensitivity design: An aerospace case study

    NARCIS (Netherlands)

    Kwakernaak, Huibert; Camacho, E.F.; Basanez, L.; Puente, de la J.A.

    2002-01-01

    The mixed sensitivity design method for multivariable linear control systems proposed in the companion paper (Kwakernaak, 2001) is applied to the design of a stability augmentation system for the longitudinal motion of a fighter airplane previously studied by Safonov and Chiang (1988). Both $H_\\inft

  20. Nuclear-Powered GPS Spacecraft Design Study

    Energy Technology Data Exchange (ETDEWEB)

    Raab, Bernard

    1977-05-01

    This is the final report of a study to investigate the potential benefits of a nuclear (radioisotope) - powered satellite for advanced phases of the Global Positioning System (GPS) program. The critical parameters were: power to user; mean mission duration; orbital predictability; thermal control of on-board frequency standards; and vulnerability. The reference design approach is described, and input data are given for two power systems that are under development: an organic Rankine system and a Brayton cycle system. Reference design details are provided and structural design and analysis are discussed, as well as thermal design and analysis. A higher altitude version is also considered.

  1. Flight Path Recovery System (FPRS) design study

    Energy Technology Data Exchange (ETDEWEB)

    1978-09-01

    The study contained herein presents a design for a Flight Path Recovery System (FPPS) for use in the NURE Program which will be more accurate than systems presently used, provide position location data in digital form suitable for automatic data processing, and provide for flight path recovery in a more economic and operationally suitable manner. The design is based upon the use of presently available hardware and technoloy, and presents little, it any, development risk. In addition, a Flight Test Plan designed to test the FPRS design concept is presented.

  2. Sequential design approaches for bioequivalence studies with crossover designs.

    Science.gov (United States)

    Potvin, Diane; DiLiberti, Charles E; Hauck, Walter W; Parr, Alan F; Schuirmann, Donald J; Smith, Robert A

    2008-01-01

    The planning of bioequivalence (BE) studies, as for any clinical trial, requires a priori specification of an effect size for the determination of power and an assumption about the variance. The specified effect size may be overly optimistic, leading to an underpowered study. The assumed variance can be either too small or too large, leading, respectively, to studies that are underpowered or overly large. There has been much work in the clinical trials field on various types of sequential designs that include sample size reestimation after the trial is started, but these have seen only little use in BE studies. The purpose of this work was to validate at least one such method for crossover design BE studies. Specifically, we considered sample size reestimation for a two-stage trial based on the variance estimated from the first stage. We identified two methods based on Pocock's method for group sequential trials that met our requirement for at most negligible increase in type I error rate.

  3. Research Design in Marital Adjustment Studies.

    Science.gov (United States)

    Croake, James W.; Lyon, Rebecca S.

    1978-01-01

    The numerous marital adjustment studies which exist in the literature are confounded by basic design problems. Marital stability should be the baseline for data. It is then possible to discuss "happiness,""success,""adjustment," and "satisfaction." (Author)

  4. Studying Design Engineers Use Of Information Systems

    DEFF Research Database (Denmark)

    Restrepo-Giraldo, John Dairo

    2006-01-01

    Studying information usage by design engineers involves considering technical, social, cognitive and volitional factors. This makes it challenging, especially for researchers without a cognitive psychology background. This paper presents a summary of key findings in researching information use...

  5. Study of the ship design process model for collaborative design

    Science.gov (United States)

    He, Ze; Qiu, Chang-Hua; Wang, Neng-Jian

    2005-09-01

    The ship design process model is the basis for developing the ship collaborative design system under network environment. According to the characteristics of the ship design, a method for dividing the ship design process into, three layers is pat forward, that is project layer, design task layer and design activity layer, then the formalized definitions of the ship design process model, the decomposing principles of the ship design process and the architecture of the ship collaborative design (SDPM) system are presented. This method simplifies the activity network makes the optimization and adjustment of the design plan convenient and also makes the design process easier to control and change, at last the architecture of the ship collaborative design system is discussed.

  6. Study of the ship design process model for collaborative design

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    The ship design process model is the basis for developing the ship collaborative design system under network environment.According to the characteristics of the ship design, a method for dividing the ship design process into three layers is pat forward, that is project layer, design task layer and design activity layer, then the formalized definitions of the ship design process model, the decomposing principles of the ship design process and the architecture of the ship collaborative design (SDPM) system are presented. This method simplifies the activity network, makes the optimization and adjustment of the design plan convenient and also makes the design process easier to control and change, at last the architecture of the ship collaborative design system is discussed.

  7. Improving the analysis of designed studies by combining statistical modelling with study design information

    NARCIS (Netherlands)

    Thissen, U.; Wopereis, S.; van Berg, S.A.A.; Bobeldijk, I.; Kleemann, R.; Kooistra, T.; van Dijk, K.W.; van Ommen, B.; Smilde, A.K.

    2009-01-01

    Background: In the fields of life sciences, so-called designed studies are used for studying complex biological systems. The data derived from these studies comply with a study design aimed at generating relevant information while diminishing unwanted variation (noise). Knowledge about the study

  8. Rhetorical Design Studies: The Art of Making Design Choices Explicit

    DEFF Research Database (Denmark)

    Halstrøm, Per L.

    2017-01-01

    Design has the potential to affect the situations we are in, the choices we make and the beliefs we live by. Being such an affective field, one might expect that canonized design thinking models and methods would be much concerned with how designers can discover arguments for their design choices...

  9. Interactive design computation: a case study on quantum design paradigm

    NARCIS (Netherlands)

    Feng, H.

    2013-01-01

    The ever-increasing complexity of design processes fosters novel design computation models to be employed in architectural research and design in order to facilitate accurate data processing and refined decision making. These computation models have enabled designers to work with complex geometry an

  10. Controlled air incinerator conceptual design study

    Energy Technology Data Exchange (ETDEWEB)

    1982-01-01

    This report presents a conceptual design study for a controlled air incinerator facility for incineration of low level combustible waste at Three Mile Island Unit 2 (TMI-2). The facility design is based on the use of a Helix Process Systems controlled air incinerator. Cost estimates and associated engineering, procurement, and construction schedules are also provided. The cost estimates and schedules are presented for two incinerator facility designs, one with provisions for waste ash solidification, the other with provisions for packaging the waste ash for transport to an undefined location.

  11. Engineering study for ISSTRS design concept

    Energy Technology Data Exchange (ETDEWEB)

    Hertzel, J.S.

    1997-01-31

    Los Alamos Technical Associates, Inc., is pleased to transmit the attached Conceptual Design Package for the Initial Single Shell Tank Retrieval System (ISSTRS), 90% Conceptual Design Review. The package includes the following: (1) ISSTRS Trade Studies: (a) Retrieval Facility Cooling Requirements; (b) Equipment Re-usability between Project W-320 and Tanks 241-C-103 and 241-C-1 05; (c) Sluice Line Options; and (d) Options for the Location of Tanks AX-103 and A-1 02 HVAC Equipment; (2) Drawings; (3) Risk Management Plan; (4) 0850 Interface Control Document; (5) Requirements Traceability Report; and (6) Project Design Specification.

  12. Sound in new media and design studies

    OpenAIRE

    Özcan, Oğuzhan; Tahiroğlu, Koray; Ikonen, Antti

    2014-01-01

    56 DesignIssues: Volume 30, Number 2 Spring 2014 © 2014 Massachusetts Institute of Technology Sound in New Media and Design Studies Koray Tahiro˘glu, O˘guzhan Özcan, Antti Ikonen Introduction The effect of new media on the computerization of cultural prac-tices has moved to a new level and has become more open, com-mon, and prevailing as we deal with new forms of artistic creation and design processes in supporting higher education. Massive changes have occurr...

  13. Distribution Network Design--literature study based

    OpenAIRE

    Li, Ang

    2012-01-01

    The focus of this research is companies' outbound distribution network design in supply chain management. Within the present competitive market, it is a fundamental importance for companies to achieve high level business performance with an effective supply chain. Outbound distribution network design as an important part in supply chain management, to a large extent decides whether companies can fulfill customers' requirement or not. Therefore, such a study is important for manufacturers and ...

  14. Conceptual study of advanced PWR core design

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Young Jin; Chang, Moon Hee; Kim, Keung Ku; Joo, Hyung Kuk; Kim, Young Il; Noh, Jae Man; Hwang, Dae Hyun; Kim, Taek Kyum; Yoo, Yon Jong

    1997-09-01

    The purpose of this project is for developing and verifying the core design concepts with enhanced safety and economy, and associated methodologies for core analyses. From the study of the sate-of-art of foreign advanced reactor cores, we developed core concepts such as soluble boron free, high convertible and enhanced safety core loaded semi-tight lattice hexagonal fuel assemblies. To analyze this hexagonal core, we have developed and verified some neutronic and T/H analysis methodologies. HELIOS code was adopted as the assembly code and HEXFEM code was developed for hexagonal core analysis. Based on experimental data in hexagonal lattices and the COBRA-IV-I code, we developed a thermal-hydraulic analysis code for hexagonal lattices. Using the core analysis code systems developed in this project, we designed a 600 MWe core and studied the feasibility of the core concepts. Two additional scopes were performed in this project : study on the operational strategies of soluble boron free core and conceptual design of large scale passive core. By using the axial BP zoning concept and suitable design of control rods, this project showed that it was possible to design a soluble boron free core in 600 MWe PWR. The results of large scale core design showed that passive concepts and daily load follow operation could be practiced. (author). 15 refs., 52 tabs., 101 figs.

  15. Impact of implementing electronic clinical practice guidelines for the diagnosis, control and treatment of cardiovascular risk factors: A pre-post controlled study

    Directory of Open Access Journals (Sweden)

    Eva Comin

    2017-08-01

    Conclusions: Computerized clinical practice guidelines are an effective tool for the control and follow-up of patients diagnosed with hypertension, type 2 diabetes mellitus, and hypercholesterolaemia. The usefulness of computerized clinical practice guidelines to diagnose and adequately treat individuals with these disorders remains unclear.

  16. Experimental design of a waste glass study

    Energy Technology Data Exchange (ETDEWEB)

    Piepel, G.F.; Redgate, P.E.; Hrma, P.

    1995-04-01

    A Composition Variation Study (CVS) is being performed to support a future high-level waste glass plant at Hanford. A total of 147 glasses, covering a broad region of compositions melting at approximately 1150{degrees}C, were tested in five statistically designed experimental phases. This paper focuses on the goals, strategies, and techniques used in designing the five phases. The overall strategy was to investigate glass compositions on the boundary and interior of an experimental region defined by single- component, multiple-component, and property constraints. Statistical optimal experimental design techniques were used to cover various subregions of the experimental region in each phase. Empirical mixture models for glass properties (as functions of glass composition) from previous phases wee used in designing subsequent CVS phases.

  17. Measurable Changes in Pre-Post Test Scores in Iraqi 4-H Leader’s Knowledge of Animal Science Production Principles

    Directory of Open Access Journals (Sweden)

    Justen O. Smith

    2015-06-01

    Full Text Available The 4-H volunteer program is a new concept to the people of Iraq, for decades the country has been closed to western ideas. Iraqi culture and the Arabic customs have not embraced the volunteer concept and even more the concept of scientific animal production technologies designed to increase profitability for producers. In 2011 the USAID-Inma Agribusiness program teamed with the Iraq 4-H program to create youth and community entrepreneurship opportunities for widowed families. Iraq 4-H provided the youth members and adult volunteers and Inma provided the financial capital (livestock and the animal science training program for the volunteers. The purpose of this study was to measure the knowledge level gained through intensive animal science training for Iraqi 4-H volunteers. Researchers designed and implemented a pre and post test to measure the knowledge of fifteen volunteers who participated in the three day course. The pretest exposed a general lack of animal science knowledge of all volunteers; over 80% of the participants incorrectly answered the questions. However, the post-test indicated positive change in the participants understanding of animal science production principles.

  18. An Exploratory Study Using Cortisol to Describe the Response of Incarcerated Women IPV Survivors to MAMBRA Intervention

    Science.gov (United States)

    2016-01-01

    Objective. To determine if incarcerated women survivors of IPV had a physiological response to the Music and Account-Making for Behavioral-Related Adaptation (MAMBRA) intervention, as measured by cortisol levels. Methods. A single-group repeated measures designed exploratory study was used to pilot-test MAMBRA. A convenience sample (n = 33) was recruited in a Midwestern women's correctional facility. Serving as their own control, participants provided demographics and pre-/post-MAMBRA salivary samples while attending four MAMBRA sessions. Baseline data were compared to participants' data collected over the remaining 3 MAMBRA sessions. Data were analyzed with descriptive and univariate statistics with an alpha of .05 and post-hoc power of .65. Results. Participants were predominantly White (52%), single (80%), and early middle-aged (x-AGE=38.7±9.4), with a history of physical/nonphysical spousal abuse. Using a subsample (n = 26), salivary cortisol decreased between the pre-/post-MAMBRA over the sessions (F(3,75) = 4.59, p < .01). Conclusion. Participants had a physiological response to the MAMBRA intervention as evidenced by the decreased cortisol between the pre-/post-MAMBRA. This is the first step in examining MAMBRA's clinical utility as an intervention for female IPV survivors. Future longitudinal studies will examine MAMBRA's effectiveness given this change in cortisol. PMID:27672452

  19. Deepening Kindergarteners' Science Vocabulary: A Design Study

    Science.gov (United States)

    Parsons, Allison Ward; Bryant, Camille Lawrence

    2016-01-01

    Early, effective instruction to introduce both science vocabulary and general academic language may help children build a strong conceptual and linguistic foundation for later instruction. In this study, a design research intervention was employed to expose children to a variety of interrelated science content words to increase both the breadth…

  20. Study designs for PDSA quality improvement research.

    Science.gov (United States)

    Speroff, Theodore; O'Connor, Gerald T

    2004-01-01

    The purpose of this article is to discuss strengths and weaknesses of quasi-experimental designs used in health care quality improvement research. The target groups for this article are investigators in plan-do-study-act (PDSA) quality improvement initiatives who wish to improve the rigor of their methodology and publish their work and reviewers who evaluate the quality of research proposals or published work. A primary purpose of PDSA quality improvement research is to establish a functional relationship between process changes in systems of health care and variation in outcomes. The time series design is the fundamental paradigm for demonstrating such functional relationships. The rigor of a PDSA quality improvement study design is strengthened using replication schemes and research methodology to address extraneous factors that weaken validity of observational studies. The design of PDSA quality improvement research should follow from the purpose and context of the project. Improving the rigor of the quality improvement literature will build a stronger foundation and more convincing justification for the study and practice of quality improvement in health care.

  1. The quality of the evidence base for clinical pathway effectiveness: Room for improvement in the design of evaluation trials

    Science.gov (United States)

    2012-01-01

    Background The purpose of this article is to report on the quality of the existing evidence base regarding the effectiveness of clinical pathway (CPW) research in the hospital setting. The analysis is based on a recently published Cochrane review of the effectiveness of CPWs. Methods An integral component of the review process was a rigorous appraisal of the methodological quality of published CPW evaluations. This allowed the identification of strengths and limitations of the evidence base for CPW effectiveness. We followed the validated Cochrane Effective Practice and Organisation of Care Group (EPOC) criteria for randomized and non-randomized clinical pathway evaluations. In addition, we tested the hypotheses that simple pre-post studies tend to overestimate CPW effects reported. Results Out of the 260 primary studies meeting CPW content criteria, only 27 studies met the EPOC study design criteria, with the majority of CPW studies (more than 70 %) excluded from the review on the basis that they were simple pre-post evaluations, mostly comparing two or more annual patient cohorts. Methodologically poor study designs are often used to evaluate CPWs and this compromises the quality of the existing evidence base. Conclusions Cochrane EPOC methodological criteria, including the selection of rigorous study designs along with detailed descriptions of CPW development and implementation processes, are recommended for quantitative evaluations to improve the evidence base for the use of CPWs in hospitals. PMID:22709274

  2. Thermodynamic Studies for Drug Design and Screening

    Science.gov (United States)

    Garbett, Nichola C.; Chaires, Jonathan B.

    2012-01-01

    Introduction A key part of drug design and development is the optimization of molecular interactions between an engineered drug candidate and its binding target. Thermodynamic characterization provides information about the balance of energetic forces driving binding interactions and is essential for understanding and optimizing molecular interactions. Areas covered This review discusses the information that can be obtained from thermodynamic measurements and how this can be applied to the drug development process. Current approaches for the measurement and optimization of thermodynamic parameters are presented, specifically higher throughput and calorimetric methods. Relevant literature for this review was identified in part by bibliographic searches for the period 2004 – 2011 using the Science Citation Index and PUBMED and the keywords listed below. Expert opinion The most effective drug design and development platform comes from an integrated process utilizing all available information from structural, thermodynamic and biological studies. Continuing evolution in our understanding of the energetic basis of molecular interactions and advances in thermodynamic methods for widespread application are essential to realize the goal of thermodynamically-driven drug design. Comprehensive thermodynamic evaluation is vital early in the drug development process to speed drug development towards an optimal energetic interaction profile while retaining good pharmacological properties. Practical thermodynamic approaches, such as enthalpic optimization, thermodynamic optimization plots and the enthalpic efficiency index, have now matured to provide proven utility in design process. Improved throughput in calorimetric methods remains essential for even greater integration of thermodynamics into drug design. PMID:22458502

  3. Advanced turbine systems: Studies and conceptual design

    Energy Technology Data Exchange (ETDEWEB)

    van der Linden, S.; Gnaedig, G.; Kreitmeier, F.

    1993-11-01

    The ABB selection for the Advanced Turbine System (ATS) includes advanced developments especially in the hot gas path of the combustion turbine and new state-of-the-art units such as the steam turbine and the HRSG. The increase in efficiency by more than 10% multiplicative compared to current designs will be based on: (1) Turbine Inlet Temperature Increase; (2) New Cooling Techniques for Stationary and Rotating Parts; and New Materials. Present, projected component improvements that will be introduced with the above mentioned issues will yield improved CCSC turbine performance, which will drive the ATS selected gas-fired reference CC power plant to 6 % LHV or better. The decrease in emission levels requires a careful optimization of the cycle design, where cooling air consumption has to be minimized. All interfaces of the individual systems in the complete CC Plant need careful checks, especially to avoid unnecessary margins in the individual designs. This study is an important step pointing out the feasibility of the ATS program with realistic goals set by DOE, which, however, will present challenges for Phase II time schedule of 18 months. With the approach outlined in this study and close cooperation with DOE, ATS program success can be achieved to deliver low emissions and low cost of electricity by the year 2002. The ABB conceptual design and step approach will lead to early component demonstration which will help accelerate the overall program objectives.

  4. Design of the BRISC study: a multicentre controlled clinical trial to optimize the communication of breast cancer risks in genetic counselling

    Science.gov (United States)

    Ockhuysen-Vermey, Caroline F; Henneman, Lidewij; van Asperen, Christi J; Oosterwijk, Jan C; Menko, Fred H; Timmermans, Daniëlle RM

    2008-01-01

    Background Understanding risks is considered to be crucial for informed decision-making. Inaccurate risk perception is a common finding in women with a family history of breast cancer attending genetic counseling. As yet, it is unclear how risks should best be communicated in clinical practice. This study protocol describes the design and methods of the BRISC (Breast cancer RISk Communication) study evaluating the effect of different formats of risk communication on the counsellee's risk perception, psychological well-being and decision-making regarding preventive options for breast cancer. Methods and design The BRISC study is designed as a pre-post-test controlled group intervention trial with repeated measurements using questionnaires. The intervention-an additional risk consultation-consists of one of 5 conditions that differ in the way counsellee's breast cancer risk is communicated: 1) lifetime risk in numerical format (natural frequencies, i.e. X out of 100), 2) lifetime risk in both numerical format and graphical format (population figures), 3) lifetime risk and age-related risk in numerical format, 4) lifetime risk and age-related risk in both numerical format and graphical format, and 5) lifetime risk in percentages. Condition 6 is the control condition in which no intervention is given (usual care). Participants are unaffected women with a family history of breast cancer attending one of three participating clinical genetic centres in the Netherlands. Discussion The BRISC study allows for an evaluation of the effects of different formats of communicating breast cancer risks to counsellees. The results can be used to optimize risk communication in order to improve informed decision-making among women with a family history of breast cancer. They may also be useful for risk communication in other health-related services. Trial registration Current Controlled Trials ISRCTN14566836. PMID:18834503

  5. Design of the BRISC study: a multicentre controlled clinical trial to optimize the communication of breast cancer risks in genetic counselling

    Directory of Open Access Journals (Sweden)

    Menko Fred H

    2008-10-01

    Full Text Available Abstract Background Understanding risks is considered to be crucial for informed decision-making. Inaccurate risk perception is a common finding in women with a family history of breast cancer attending genetic counseling. As yet, it is unclear how risks should best be communicated in clinical practice. This study protocol describes the design and methods of the BRISC (Breast cancer RISk Communication study evaluating the effect of different formats of risk communication on the counsellee's risk perception, psychological well-being and decision-making regarding preventive options for breast cancer. Methods and design The BRISC study is designed as a pre-post-test controlled group intervention trial with repeated measurements using questionnaires. The intervention-an additional risk consultation-consists of one of 5 conditions that differ in the way counsellee's breast cancer risk is communicated: 1 lifetime risk in numerical format (natural frequencies, i.e. X out of 100, 2 lifetime risk in both numerical format and graphical format (population figures, 3 lifetime risk and age-related risk in numerical format, 4 lifetime risk and age-related risk in both numerical format and graphical format, and 5 lifetime risk in percentages. Condition 6 is the control condition in which no intervention is given (usual care. Participants are unaffected women with a family history of breast cancer attending one of three participating clinical genetic centres in the Netherlands. Discussion The BRISC study allows for an evaluation of the effects of different formats of communicating breast cancer risks to counsellees. The results can be used to optimize risk communication in order to improve informed decision-making among women with a family history of breast cancer. They may also be useful for risk communication in other health-related services. Trial registration Current Controlled Trials ISRCTN14566836.

  6. Service Design, insights from nine case studies

    NARCIS (Netherlands)

    Enninga, Tanja; Manschot, M.M.; Gessel, C. van; Gijbels, J.; Lugt, Remko van der; Sleeswijk Visser, Sjoukje; Verhoeven, Fenne; Godfroij, Berit

    2013-01-01

    Service design is literally the design of services. Service designers improve existing services or design completely new ones. Nothing new so far. Services have been around for centuries, and every service was conceived and designed by someone. However, service design takes a different angle; a diff

  7. Interim report on the tandem mirror hybrid design study

    Energy Technology Data Exchange (ETDEWEB)

    Moir, R.W. (ed.)

    1979-08-01

    The initial phase of a 2-year design study of a tandem mirror fusion reactor is presented. The following chapters are included: (1) mechanical design of the plant; (2) plasma physics; (3) blanket design; (4) magnet design; (5) injector design; (6) direct convertor design; (7) balance of plant design; (8) fission burner reactor; (9) environment and safety; and (10) economic analysis. (MOW)

  8. Design and analysis of biomedical studies

    DEFF Research Database (Denmark)

    Hansen, Merete Kjær

    Biomedicine is a field that has great influence on the majority of mankind. The constant development has considerably changed our way of life during the last centuries. This has been achieved through the dedication of biomedical researchers along with the tremendous ressources that over time have...... been allocated this field. It is utterly important to utilize these ressources responsibly and efficiently by constantly striving to ensure high-quality biomedical studies. This involves the use of a sound statistical methodology regarding both the design and analysis of biomedical studies. The focus...... for biomedical studies are a recurring theme in this thesis. Data collected in some biomedical studies are positively skewed; hence methods relying on the normal distribution are not directly applicable. We investigated how data from one of these studies are suitably analyzed. We extracted 23 different summary...

  9. Quantitative methods for studying design protocols

    CERN Document Server

    Kan, Jeff WT

    2017-01-01

    This book is aimed at researchers and students who would like to engage in and deepen their understanding of design cognition research. The book presents new approaches for analyzing design thinking and proposes methods of measuring design processes. These methods seek to quantify design issues and design processes that are defined based on notions from the Function-Behavior-Structure (FBS) design ontology and from linkography. A linkograph is a network of linked design moves or segments. FBS ontology concepts have been used in both design theory and design thinking research and have yielded numerous results. Linkography is one of the most influential and elegant design cognition research methods. In this book Kan and Gero provide novel and state-of-the-art methods of analyzing design protocols that offer insights into design cognition by integrating segmentation with linkography by assigning FBS-based codes to design moves or segments and treating links as FBS transformation processes. They propose and test ...

  10. Design Study for Pulsed Proton Beam Generation

    Directory of Open Access Journals (Sweden)

    Han-Sung Kim

    2016-02-01

    Full Text Available Fast neutrons with a broad energy spectrum, with which it is possible to evaluate nuclear data for various research fields such as medical applications and the development of fusion reactors, can be generated by irradiating proton beams on target materials such as beryllium. To generate short-pulse proton beam, we adopted a deflector and slit system. In a simple deflector with slit system, most of the proton beam is blocked by the slit, especially when the beam pulse width is short. Therefore, the available beam current is very low, which results in low neutron flux. In this study, we proposed beam modulation using a buncher cavity to increase the available beam current. The ideal field pattern for the buncher cavity is sawtooth. To make the field pattern similar to a sawtooth waveform, a multiharmonic buncher was adopted. The design process for the multiharmonic buncher includes a beam dynamics calculation and three-dimensional electromagnetic simulation. In addition to the system design for pulsed proton generation, a test bench with a microwave ion source is under preparation to test the performance of the system. The design study results concerning the pulsed proton beam generation and the test bench preparation with some preliminary test results are presented in this paper.

  11. Multi-Band Feeds: A Design Study

    CERN Document Server

    Maan, Yogesh; Raja, Wasim; Mehta, Nikhil

    2012-01-01

    Broadband antenna feeds are of particular interest to existing and future radio telescopes for multi-frequency studies of astronomical sources. Although a 1:15 range in frequency is difficult to achieve, the well-known Eleven feed design offers a relatively uniform response over such a range, and reasonably well-matched responses in E & H planes. However, given the severe Radio Frequency Interference in several bands over such wide spectral range, one desires to selectively reject the corresponding bands. With this view, we have explored the possibilities of having a multi-band feed antenna spanning a wide frequency range, but which would have good response only in a number of pre-selected (relatively) RFI-free windows (for a particular telescope-site). The designs we have investigated use the basic configuration of pairs of dipoles as in the Eleven feed, but use simple wire dipoles instead of folded dipoles used in the latter. From our study of the two designs we have investigated, we find that the desig...

  12. X-ray tubes study and design

    CERN Document Server

    Sardari, D

    1990-01-01

    This thesis contain both theoretical and experimental works. Theoretical aspect includes X-Ray tubes case study and design principles, in the introduced design process, anode-cathode distance, vacuum needed, filament size, anode face angle and shape and size of focusing electrodes can be found. A method for specification of tungsten lager thickness on anode is also introduced. Using computer simulation, electron trajectory between cathode-anode is obtained, This work is presented in the first International Conference on Control and Modeling, Tehran, 1990. Experimental work contains manufacturing more than 10 tubes and test each of them. One of these tubes can with stand up to 50 KV. Filament can be heated by passing a 2.1 A current. In these conditions anode current is 1.2 m A. Using this tube, some radiographs have been taken.

  13. Design Study: Rocket Based MHD Generator

    Science.gov (United States)

    1997-01-01

    This report addresses the technical feasibility and design of a rocket based MHD generator using a sub-scale LOx/RP rocket motor. The design study was constrained by assuming the generator must function within the performance and structural limits of an existing magnet and by assuming realistic limits on (1) the axial electric field, (2) the Hall parameter, (3) current density, and (4) heat flux (given the criteria of heat sink operation). The major results of the work are summarized as follows: (1) A Faraday type of generator with rectangular cross section is designed to operate with a combustor pressure of 300 psi. Based on a magnetic field strength of 1.5 Tesla, the electrical power output from this generator is estimated to be 54.2 KW with potassium seed (weight fraction 3.74%) and 92 KW with cesium seed (weight fraction 9.66%). The former corresponds to a enthalpy extraction ratio of 2.36% while that for the latter is 4.16%; (2) A conceptual design of the Faraday MHD channel is proposed, based on a maximum operating time of 10 to 15 seconds. This concept utilizes a phenolic back wall for inserting the electrodes and inter-electrode insulators. Copper electrode and aluminum oxide insulator are suggested for this channel; and (3) A testing configuration for the sub-scale rocket based MHD system is proposed. An estimate of performance of an ideal rocket based MHD accelerator is performed. With a current density constraint of 5 Amps/cm(exp 2) and a conductivity of 30 Siemens/m, the push power density can be 250, 431, and 750 MW/m(sup 3) when the induced voltage uB have values of 5, 10, and 15 KV/m, respectively.

  14. Study and Design of LED Lighting Systems

    Directory of Open Access Journals (Sweden)

    Li Cheng

    2013-06-01

    Full Text Available In this study, the optical characteristics, thermal characteristics, electrical characteristics of the LED device are studied. After analysis of the significance of the optical model, we establish the model of the LED light source using optical simulation software to analyze the impact of modeling four factors and law, based on ray tracing model intensity distribution with the manufacturers. On this basis, we expand the LED secondary optical design, namely, increasing of LDE method to the light level. After comparing different forms of non-imaging optical components, combined with the actual situation, the final choice is the system composed of rotating parabolic reflector with LDE. Besides, the reflected changing the relative position of the body and LDE space lead to the normal light intensity of the entire system appearing two peaks, but their causes are different. In addition, the method of combining theoretical analysis and computer simulations to study the distribution of LDE array illumination is utilized. Formula on the illumination distribution in the LDB array to a plane parallel thereto is deduced, which is verified by computer simulation and agrees well with it. A quantitative study of the factors affecting the road surface illuminance distribution is made on the basis of previous study, combined with the actual road lighting works. These factors are: LDE array form, the number of LED, spacing between LDE, LDE interval between the street lamps. The derived entire road illumination distribution formula and the corresponding curve gives a basic method for the analysis of such practical problems related outcomes for the LDE illumination optical system design and research basis.

  15. Imaginative resonance training (IRT) achieves elimination of amputees' phantom pain (PLP) coupled with a spontaneous in-depth proprioception of a restored limb as a marker for permanence and supported by pre-post functional magnetic resonance imaging (fMRI).

    Science.gov (United States)

    Meyer, Paul; Matthes, Christoph; Kusche, Karl Erwin; Maurer, Konrad

    2012-05-31

    Non-pharmacological approaches such as mirror therapy and graded motor imagery often provide amelioration of amputees' phantom limb pain (PLP), but elimination has proved difficult to achieve. Proprioception of the amputated limb has been noted in studies to be defective and/or distorted in the presence of PLP, but has not, apparently, been researched for various stages of amelioration up to the absence of PLP. Previous studies using functional magnetic resonance imaging (fMRI) suggested that pathological cortical reorganisation after amputation may be the underlying neurobiological correlate of PLP. We report two cases of permanent elimination of PLP after application of imaginative resonance training. The patients, 69 years and 84 years old, reported freedom from PLP together with in-depth achievement of proprioception of a restored limb at the end of the treatment, which may thus be taken as an indication of permanence. Pre/post fMRI for the first case showed, against a group of healthy controls, analogous changes of activation in the sensorimotor cortex.

  16. Southampton mealtime assistance study: design and methods

    Directory of Open Access Journals (Sweden)

    Roberts Helen C

    2013-01-01

    Full Text Available Abstract Background Malnutrition is common in older people in hospital and is associated with adverse clinical outcomes including increased mortality, morbidity and length of stay. This has raised concerns about the nutrition and diet of hospital in-patients. A number of factors may contribute to low dietary intakes in hospital, including acute illness and cognitive impairment among in-patients. The extent to which other factors influence intake such as a lack of help at mealtimes, for patients who require assistance with eating, is uncertain. This study aims to evaluate the effectiveness of using trained volunteer mealtime assistants to help patients on an acute medical ward for older people at mealtimes. Methods/design The study design is quasi-experimental with a before (year one and after (year two comparison of patients on the intervention ward and parallel comparison with patients on a control ward in the same department. The intervention in the second year was the provision of trained volunteer mealtime assistance to patients in the intervention ward. There were three components of data collection that were repeated in both years on both wards. The first (primary outcome was patients’ dietary intake, collected as individual patient records and as ward-level balance data over 24 hour periods. The second was clinical outcome data assessed on admission and discharge from both wards, and 6 and 12 months after discharge. Finally qualitative data on the views and experience of patients, carers, staff and volunteers was collected through interviews and focus groups in both years to allow a mixed-method evaluation of the intervention. Discussion The study will describe the effect of provision of trained volunteer mealtime assistants on the dietary intake of older medical in-patients. The association between dietary intake and clinical outcomes including malnutrition risk, body composition, grip strength, length of hospital stay and mortality

  17. Studying feasibility and effects of a two-stage nursing staff training in residential geriatric care using a 30 month mixed-methods design [ISRCTN24344776

    Directory of Open Access Journals (Sweden)

    Hantikainen Virpi

    2011-05-01

    Full Text Available Abstract Background Transfer techniques and lifting weights often cause back pain and disorders for nurses in geriatric care. The Kinaesthetics care conception claims to be an alternative, yielding benefits for nurses as well as for clients. Starting a multi-step research program on the effects of Kinaesthetics, we assess the feasibility of a two-stage nursing staff training and a pre-post research design. Using quantitative and qualitative success criteria, we address mobilisation from the bed to a chair and backwards, walking with aid and positioning in bed on the staff level as well as on the resident level. In addition, effect estimates should help to decide on and to prepare a controlled trial. Methods/Design Standard basic and advanced Kinaesthetics courses (each comprising four subsequent days and an additional counselling day during the following four months are offered to n = 36 out of 60 nurses in a residential geriatric care home, who are in charge of 76 residents. N = 22 residents needing movement support are participating to this study. On the staff level, measurements include focus group discussions, questionnaires, physical strain self-assessment (Borg scale, video recordings and external observation of patient assistance skills using a specialised instrument (SOPMAS. Questionnaires used on the resident level include safety, comfort, pain, and level of own participation during mobilisation. A functional mobility profile is assessed using a specialised test procedure (MOTPA. Measurements will take place at baseline (T0, after basic training (T1, and after the advanced course (T2. Follow-up focus groups will be offered at T1 and 10 months later (T3. Discussion Ten criteria for feasibility success are established before the trial, assigned to resources (missing data, processes (drop-out of nurses and residents and science (minimum effects criteria. This will help to make rational decision on entering the next stage of the research

  18. A case study in value design

    Directory of Open Access Journals (Sweden)

    M. Sinclair

    2003-12-01

    Full Text Available The design of a special type of valve gave rise to a problem which lead the mechanical engineers who designed the valve to call in the help of the author. The final solution to the problem may not be mathematically sophisticated (in fact, it may seem trivial to some readers, but the steps through which the design team struggled and the final approach which resulted in a practically feasible solution may be of interest to other practitioners.

  19. Study on the humanization design of Television

    Institute of Scientific and Technical Information of China (English)

    郝凌飞

    2015-01-01

    Since 1924 the world’s first television was born, and now the TV has entered every household, become necessary for life products. The TV design in order to better meet people’s needs, the concept of humanity is essential to human design principles in this article as a starting point to explore the design of the TV how to better “people-oriented”.

  20. Design studies on indoor green furniture

    Institute of Scientific and Technical Information of China (English)

    徐菲

    2014-01-01

    Furniture is an important part in people's daily life, if green furniture can be achieved, for people to have a deeper understanding of green design. This paper analyzes the importance and problems of the current lifestyle of people, leads to green furniture, as well as focusing on aspects of green design furniture. Proposed should follow the “nature-based” green design basis, because it is the basis of the nature and duration requested.

  1. Studying the Creation of Design Artifacts

    DEFF Research Database (Denmark)

    Davis, Christopher J.; Hevner, Ala n R.; Weber, Barbara

    2016-01-01

    and information systems represents a highly interconnected locus in which both the generative processes of building design artifacts and articulating constructs used to evaluate their quality take place. We address this interconnectedness with an extended process-oriented research design enabling multi......-modal neurophysiological data analyses. We posit that our research will provide more comprehensive assessments of the efficacy of design processes and the evaluation of the qualities of the resulting design artifacts.......As software and information systems (IS) increase in functional sophistication, perceptions of IS quality are changing. Moving beyond issues of performance efficiency, essential qualities such as fitness for purpose, sustainability, and overall effectiveness become more complex. Creating software...

  2. Design and Phenomenology of the FEBSTAT Study

    Science.gov (United States)

    Hesdorffer, Dale C; Shinnar, Shlomo; Lewis, Darrell V; Moshé, Solomon L; Nordli, Douglas R; Pellock, John M; MacFall, James; Shinnar, Ruth C; Masur, David; Frank, L Matthew; Epstein, Leon G; Litherland, Claire; Seinfeld, Syndi; Bello, Jacqueline A; Chan, Stephen; Bagiella, Emilia; Sun, Shumei

    2012-01-01

    Purpose Febrile status epilepticus (FSE) has been associated with hippocampal injury and subsequent hipppocampal sclerosis (HS) and temporal lobe epilepsy. The FEBSTAT study was designed to prospectively examine the association between prolonged febrile seizures and development of HS and associated temporal lobe epilepsy, one of the most controversial issues in epilepsy. We report on the baseline phenomenology of the final cohorts as well as detailed aims and methodology. Methods The “Consequences of Prolonged Febrile Seizures in Childhood” (FEBSTAT) study is a prospective, multicenter study. Enrolled are children, aged 1 month to 6 years, presenting with a febrile seizure lasting 30 minutes or more based upon ambulance, emergency department, and hospital records, and parental interview. At baseline, procedures included an MRI and EEG done within 72 hours of FSE, and a detailed history and neurological examination. Baseline development and behavior are assessed at one month. The baseline assessment is repeated, with age- appropriate developmental testing at one and five years after enrollment as well as at the development of epilepsy and one year after that. Telephone calls every three months document further seizures. Two other groups of children are included: a ‘control’ group consisting of children with a first febrile seizure ascertained at Columbia University and with almost identical baseline and one year follow-up examinations and a pilot cohort of FSE from Duke University. Key findings The FEBSTAT cohort consists of 199 children with a median age at baseline of 16.0 months (Interquartile range (IQR)=12.0–24.0) and a median duration of FSE of 70.0 minutes (IQR=47.0–110.0). Seizures were continuous in 57.3% and behaviorally intermittent (without recovery in between) in 31.2%; most were partial (4;2.0%) or secondary generalized (65.8%), and almost all (98.0%) culminated in a generalized tonic clonic seizure. Of the 199 children, 86.4% had normal

  3. Design study of the storage ring EUTERPE

    Science.gov (United States)

    Xi, Boling; Botman, J. I. M.; Timmermans, C. J.; Hagedoorn, H. L.

    1992-05-01

    At present the 400 MeV electron storage ring EUTERPE is being constructed at the Eindhoven University of Technology. It is a university project set up for studies of charged particle beam dynamics and applications of synchroton radiation, and for the education of students in these fields. The design of the ring is described in this paper. Considering the requirements of users in different fields, a lattice based on a so-called triple bend achromat structure with a high flexibility has been chosen. With this lattice, different optical options, including the HBSB (high brightness, small beam), the SBL (short bunch length) and the HLF (high light flux) modes can be realized. A small emittance of 7 nm rad and a short bunch length of the order of several mm can be achieved. In the first phase the synchrotron radiation in the UV and XUV region (the critical wavelength is 8.3 nm) will be provided from the regular dipole magnets. Later on, a 10 T wiggler magnet and other special inserters will be added, and other applications and beam dynamics studies will be feasible. Bending magnets are of the parallel faced C configuration. The effective aperture of the vacuum chamber is 2.3 cm (vertical) in the bending magnets and 4.7 cm elsewhere with a working vacuum condition of 10-9 Torr. Collective effects have been studied initially. First calculations indicate that a lifetime of several hours, influenced by the Touschek effect and residual gas scattering will be achievable for a 200 mA beam in the HLF mode for the standard rf parameters. A 70 MeV racetrack microtron will serve as injector for the ring.

  4. A Case Study in CAD Design Automation

    Science.gov (United States)

    Lowe, Andrew G.; Hartman, Nathan W.

    2011-01-01

    Computer-aided design (CAD) software and other product life-cycle management (PLM) tools have become ubiquitous in industry during the past 20 years. Over this time they have continuously evolved, becoming programs with enormous capabilities, but the companies that use them have not evolved their design practices at the same rate. Due to the…

  5. Low vision goggles: optical design studies

    Science.gov (United States)

    Levy, Ofer; Apter, Boris; Efron, Uzi

    2006-08-01

    Low Vision (LV) due to Age Related Macular Degeneration (AMD), Glaucoma or Retinitis Pigmentosa (RP) is a growing problem, which will affect more than 15 million people in the U.S alone in 2010. Low Vision Aid Goggles (LVG) have been under development at Ben-Gurion University and the Holon Institute of Technology. The device is based on a unique Image Transceiver Device (ITD), combining both functions of imaging and Display in a single chip. Using the ITD-based goggles, specifically designed for the visually impaired, our aim is to develop a head-mounted device that will allow the capture of the ambient scenery, perform the necessary image enhancement and processing, and re-direct it to the healthy part of the patient's retina. This design methodology will allow the Goggles to be mobile, multi-task and environmental-adaptive. In this paper we present the optical design considerations of the Goggles, including a preliminary performance analysis. Common vision deficiencies of LV patients are usually divided into two main categories: peripheral vision loss (PVL) and central vision loss (CVL), each requiring different Goggles design. A set of design principles had been defined for each category. Four main optical designs are presented and compared according to the design principles. Each of the designs is presented in two main optical configurations: See-through system and Video imaging system. The use of a full-color ITD-Based Goggles is also discussed.

  6. Enabling students to learn: Design, implementation and assessment of a supplemental study strategies course for an introductory undergraduate biology course

    Science.gov (United States)

    Sriram, Jayanthi Sanjeevi

    Attrition in the STEM disciplines is a national problem and one of the important reasons for this is student experiences in introductory courses. A myriad of factors influence students' experiences in those courses; inadequate student preparation is one of the most cited reasons. Incoming freshmen often lack the learning strategies required to meaningfully learn and succeed in college courses. Unfortunately, the instructors have limited time and/or have little experience in teaching learning strategies. In this paper, the design, implementation, and evaluation of a Supplemental Course (SC) model that emphasizes learning strategies is presented. SC was offered concurrently with the introductory biology courses for four consecutive semesters (fall 2011 to spring 2013); for 10 weeks in fall 2012 and 7 weeks in the other semesters at Miami University. 10 weeks SC began earlier in the semester than the shorter SC. This study evaluated the effects of the SC on students' (1) performance in the introductory biology course, (2) perceived changes in self-regulation and social support, and (3) experiences in the introductory biology course before, during, and after participation in the SC. A mixed methods approach was used to address these goals. A pre-post survey was administered to obtain students' use of self-regulation strategies and social-support data. Quantitative methods were utilized to analyze content exam grades and changes in self-regulation strategies and social-support. To explore the experiences of the students, semi-structured interviews were conducted, followed by analysis using grounded theory. The findings reveal that participants of the longer duration SC (with an earlier start date) significantly improved in content exam performance, perceived use of self-regulation strategies, and social support compared to the non-participants. Participants of the shorter duration SC (with a later start date) did not significantly improve in content exam performance

  7. Changes in kinetic, kinematic, and temporal parameters of walking in people with limited ankle dorsiflexion: pre-post application of modified mobilization with movement using talus glide taping.

    Science.gov (United States)

    Yoon, Ji-yeon; Hwang, Young-in; An, Duk-hyun; Oh, Jae-seop

    2014-06-01

    The purpose of this study was to investigate the changes in passive ankle dorsiflexion range of motion (ROM), maximum plantar force, force-time integral, and time to heel off during walking between pre- and postapplication of modified mobilization with movement (MWM) using talus glide taping in people with limited ankle dorsiflexion. Eighteen feet with limited ankle dorsiflexion in 13 people were examined. Participants performed 3 different walking tasks in the following order: walking before and immediately after applying the modified MWM using talus glide taping and walking after 5-minute walking with the modified MWM using talus glide taping. A floor-mat pressure measurement system (HR-mat) was used to measure maximum plantar force, force-time integral, and time to heel off; and passive ankle dorsiflexion ROM was measured using a standard goniometer. The significance of differences was assessed using repeated one-way analysis of variance. Passive ankle dorsiflexion ROM and time to heel off were significantly increased after 5-minute walking with the modified MWM using talus glide taping compared with walking before and immediately after applying the tape. Significantly increased maximum plantar force and force-time integral on the hindfoot and significantly decreased force-time integral on the forefoot during walking after 5-minute walking were observed with the modified MWM using talus glide taping compared with before applying the tape. No significant difference between before and immediately after applying the tape was observed in any variable. Our results suggest that walking an additional 5-minute with the modified MWM using talus glide taping increased passive ankle dorsiflexion ROM and time to heel off and improved dynamic plantar loading during walking. Copyright © 2014 National University of Health Sciences. Published by Mosby, Inc. All rights reserved.

  8. Study on Case-Based Fixture Design

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Fixture is an important manufacturing activity. A fixture design system based on case-based reasoning (CBR) is proposed in this paper. A new method of case representation on the basis of fixture function is presented, where the case representation is constituted of workpiece knowledge, processing feature knowledge, and fixture feature knowledge. Running the prototype system shows that the knowledge representation method, using cases, is a better way to transform and explain the design knowledge.

  9. Case study: error rates and paperwork design.

    Science.gov (United States)

    Drury, C G

    1998-01-01

    A job instruction document, or workcard, for civil aircraft maintenance produced a number of paperwork errors when used operationally. The design of the workcard was compared to the guidelines of Patel et al [1994, Applied Ergonomics, 25 (5), 286-293]. All of the errors occurred in work instructions which did not meet these guidelines, demonstrating that the design of documentation does affect operational performance.

  10. The Study of Tactical Missile's Airframe Digital Optimization Design

    Institute of Scientific and Technical Information of China (English)

    LUO Zhiqing; QIAN Airong; LI Xuefeng; GAO Lin; LEI Jian

    2006-01-01

    Digital design and optimal are very important in modern design. The traditional design methods and procedure are not fit for the modern missile weapons research and development. Digital design methods and optimal ideas were employed to deal with this problem. The disadvantages of the traditional missile's airframe design procedure and the advantages of the digital design methods were discussed. A new concept of design process reengineering (DPR) was put forward. An integrated missile airframe digital design platform and the digital design procedure, which integrated the optimization ideas and methods, were developed. Case study showed that the design platform and the design procedure could improve the efficiency and quality of missile's airframe design, and get the more reasonable and optimal results.

  11. Initial DEMO tokamak design configuration studies

    Energy Technology Data Exchange (ETDEWEB)

    Bachmann, Christian, E-mail: christian.bachmann@efda.org [EFDA, Boltzmannstraße 2, 85748 Garching (Germany); Aiello, G. [CEA-Saclay, DEN, DM2S, SEMT, F-91191 Gif-Sur-Yvette (France); Albanese, R.; Ambrosino, R. [ENEA/CREATE, Universita di Napoli Federico II, Naples (Italy); Arbeiter, F. [Karlsruhe Institute of Technology (KIT), Karlsruhe (Germany); Aubert, J. [CEA-Saclay, DEN, DM2S, SEMT, F-91191 Gif-Sur-Yvette (France); Boccaccini, L.; Carloni, D. [Karlsruhe Institute of Technology (KIT), Karlsruhe (Germany); Federici, G. [EFDA, Boltzmannstraße 2, 85748 Garching (Germany); Fischer, U. [Karlsruhe Institute of Technology (KIT), Karlsruhe (Germany); Kovari, M. [CCFE, Culham Science Centre, Abingdon, Oxon OX14 3DB (United Kingdom); Li Puma, A. [CEA-Saclay, DEN, DM2S, SEMT, F-91191 Gif-Sur-Yvette (France); Loving, A. [CCFE, Culham Science Centre, Abingdon, Oxon OX14 3DB (United Kingdom); Maione, I. [Karlsruhe Institute of Technology (KIT), Karlsruhe (Germany); Mattei, M. [ENEA/CREATE, Universita di Napoli Federico II, Naples (Italy); Mazzone, G. [ENEA C.R. Frascati, via E. Fermi 45, 00044 Frascati, Roma (Italy); Meszaros, B. [EFDA, Boltzmannstraße 2, 85748 Garching (Germany); Palermo, I. [Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), Madrid (Spain); Pereslavtsev, P. [Karlsruhe Institute of Technology (KIT), Karlsruhe (Germany); Riccardo, V. [CCFE, Culham Science Centre, Abingdon, Oxon OX14 3DB (United Kingdom); and others

    2015-10-15

    Highlights: • A definition of main DEMO requirements. • A description of the DEMO tokamak design configuration. • A description of issues yet to be solved. - Abstract: To prepare the DEMO conceptual design phase a number of physics and engineering assessments were carried out in recent years in the frame of EFDA concluding in an initial design configuration of a DEMO tokamak. This paper gives an insight into the identified engineering requirements and constraints and describes their impact on the selection of the technologies and design principles of the main tokamak components. The EU DEMO program aims at making best use of the technologies developed for ITER (e.g., magnets, vessel, cryostat, and to some degree also the divertor). However, other systems in particular the breeding blanket require design solutions and advanced technologies that will only partially be tested in ITER. The main differences from ITER include the requirement to breed, to extract, to process and to recycle the tritium needed for plasma operation, the two orders of magnitude larger lifetime neutron fluence, the consequent radiation dose levels, which limit remote maintenance options, and the requirement to use low-activation steel for in-vessel components that also must operate at high temperature for efficient energy conversion.

  12. Epidemiological study air disaster in Amsterdam (ESADA: study design

    Directory of Open Access Journals (Sweden)

    Bramsen Inge

    2005-05-01

    Full Text Available Abstract Background In 1992, a cargo aircraft crashed into apartment buildings in Amsterdam, killing 43 victims and destroying 266 apartments. In the aftermath there were speculations about the cause of the crash, potential exposures to hazardous materials due to the disaster and the health consequences. Starting in 2000, the Epidemiological Study Air Disaster in Amsterdam (ESADA aimed to assess the long-term health effects of occupational exposure to this disaster on professional assistance workers. Methods/Design Epidemiological study among all the exposed professional fire-fighters and police officers who performed disaster-related task(s, and hangar workers who sorted the wreckage of the aircraft, as well as reference groups of their non-exposed colleagues who did not perform any disaster-related tasks. The study took place, on average, 8.5 years after the disaster. Questionnaires were used to assess details on occupational exposure to the disaster. Health measures comprised laboratory assessments in urine, blood and saliva, as well as self-reported current health measures, including health-related quality of life, and various physical and psychological symptoms. Discussion In this paper we describe and discuss the design of the ESADA. The ESADA will provide additional scientific knowledge on the long-term health effects of technological disasters on professional workers.

  13. Status of the Neutrino Factory accelerator design studies

    CERN Document Server

    Prior, Gersende

    2013-01-01

    This document is a review of the present status of the Neutrino Factory design study, after the publication of the Interim Design Report and before the publication of the Reference Design Report. The different components of the accelerator as well as their current design stage and future tasks are described here.

  14. Design Studies with DEMIRCI for SPP RFQ

    CERN Document Server

    Yasatekin, B; Alacakir, A; Unel, G

    2014-01-01

    To design a Radio Frequency Quadrupole (RFQ) is a onerous job which requires a good understanding of all the main parameters and the relevant calculations. Up to the present there are only a few software packages performing this task in a reliable way. These legacy software, though proven in time, could benefit from the modern software development tools like Object Oriented (OO) programming. In this note, a new RFQ design software, DEMIRCI is introduced. It is written entirely from scratch using C++ and based on CERN's OO ROOT library. It has a friendly graphical user interface and also a command line interface for batch calculations. It can also interact by file exchange with similar software in the field. After presenting the generic properties of DEMIRCI, its compatibility with similar software packages is discussed based on the results from the reference design parameters of SPP (SNRTC Project Prometheus), a demonstration accelerator at Ankara, Turkey.

  15. Conceptual design studies for a CEPC detector

    Science.gov (United States)

    Chekanov, S. V.; Demarteau, M.

    2016-11-01

    The physics potential of the Circular Electron Positron Collider (CEPC) can be significantly strengthened by two detectors with complementary designs. A promising detector approach based on the Silicon Detector (SiD) designed for the International Linear Collider (ILC) is presented. Several simplifications of this detector for the lower energies expected at the CEPC are proposed. A number of cost optimizations of this detector are illustrated using full detector simulations. We show that the proposed changes will enable one to reach the physics goals at the CEPC.

  16. Conceptual Design Studies for a CEPC Detector

    CERN Document Server

    Chekanov, S V

    2016-01-01

    The physics potential of the Circular Electron Positron Collider (CEPC) can be significantly strengthened by two detectors with complementary designs. A promising detector approach based on the Silicon Detector (SiD) designed for the International Linear Collider (ILC) is presented. Several simplifications of this detector for the lower energies expected at the CEPC are proposed. A number of cost optimizations of this detector are illustrated using full detector simulations. We show that the proposed changes will enable to reach the physics goals at the CEPC.

  17. Feasibility study of an Integrated Program for Aerospace vehicle Design (IPAD). Volume 4: IPAD system design

    Science.gov (United States)

    Goldfarb, W.; Carpenter, L. C.; Redhed, D. D.; Hansen, S. D.; Anderson, L. O.; Kawaguchi, A. S.

    1973-01-01

    The computing system design of IPAD is described and the requirements which form the basis for the system design are discussed. The system is presented in terms of a functional design description and technical design specifications. The functional design specifications give the detailed description of the system design using top-down structured programming methodology. Human behavioral characteristics, which specify the system design at the user interface, security considerations, and standards for system design, implementation, and maintenance are also part of the technical design specifications. Detailed specifications of the two most common computing system types in use by the major aerospace companies which could support the IPAD system design are presented. The report of a study to investigate migration of IPAD software between the two candidate 3rd generation host computing systems and from these systems to a 4th generation system is included.

  18. THE RELIABILITY STUDY OF MINE DESIGN

    Institute of Scientific and Technical Information of China (English)

    彭世济; 张达贤; 习永峰; 卢明银; 孙洪泉

    1991-01-01

    The method of reliability analysis of mineral reserve estimation, mining construction, mining technological system and surface mine investment in mine design is discussed in this paper. On the basis of this method, the questions, such as "whether the planned production and predicted economic effectiveness could be obtained", can be answered, and corresponding measures can be taken.

  19. Rationale and Design of the 'MITOCARE' Study

    DEFF Research Database (Denmark)

    Clemmensen, Peter

    2012-01-01

    Treatment of acute ST-elevation myocardial infarction (STEMI) by reperfusion using percutaneous coronary intervention (PCI) or thrombolysis has provided clinical benefits; however, it also induces considerable cell death. This process is called reperfusion injury. The continuing high rates of mor...... understanding of the complex pathophysiology underlying myocardial injury after STEMI. The present paper describes the rationale, design and the methods of the trial....

  20. Tokamak blanket design study, final report

    Energy Technology Data Exchange (ETDEWEB)

    1980-08-01

    A cylindrical module concept was developed, analyzed, and incorporated in a tokamak blanket system that includes piping systems, vacuum boundary sealing, and support structures. The design is based on the use of state-of-the-art structural materials (20% cold-worked type 316 stainless steel), lithium as the breeding material, and pressurized helium as the coolant. The module design consists of nested concentric cylinders (with an outer diameter of 10 cm) and features direct wall cooling by helium flowing between the outer (first-wall) cylinder and the inner (lithium-containing) cylinder. Each cylinder can withstand full coolant pressure, thus enhancing reliability. Results show that stainless steel is a viable material for a first wall subjected to a neutron wall loading of 4 MW/m/sup 2/ and a particle heat flux of 1 MW/m/sup 2/. Lifetime analysis shows that the first-wall design meets the goal of operating at 20-min cycles with 95% duty for 100,000 cycles. To reduce system complexity, a larger 20-cm-diam module also was analyzed for incorporation in the blanket assembly. Reliability assessment indicates that it may be possible to double the module in size from 10 to 20 cm in diameter. With a modest increase in coolant pumping power, a blanket assembly comprising 20-cm-diam modules can still achieve 100,000 operating cycles - equivalent to a 3.6-year design lifetime - with only one or two helium coolant leaks into the plasma.

  1. Research designs for experimental single-case studies

    Directory of Open Access Journals (Sweden)

    Ralf Spieß

    2012-09-01

    Full Text Available This overview describes the most important designs for single case experimental studies, which are ABAB-design, multiple baseline design, alternating treatments design and changing criterion design. The logic of experimental control in single case studies is explained and it is described, how these different designs are able to provide internal validity and enable causal interpretations of intervention outcome. An important precondition of valid interpretation is objective and reliable data assessment. Data evaluation by visual inspection is explained and several methods of statistical data analysis are discussed. To establish generability across persons, situations, and settings, the importance of replication studies is highlighted.

  2. Crossover versus parallel designs: dose-escalation design comparisons for first-in-human studies.

    Science.gov (United States)

    Yan, Zhiwu; Hosmane, Balakrishna; Locke, Charles

    2013-01-01

    We study the statistical efficiency for rising-dose designs in the context of first-in-human studies. Specifically, we identify a class of crossover designs that are appealing in terms of both subject safety and statistical efficiency and, for a three-period, two-panel design in such a class, we compare its A-efficiency relative to the corresponding parallel designs and optimal/efficient crossover designs, respectively, under various plausible models. In the meantime, we also evaluate the impact of inclusion of baseline measurements as a covariate in the statistical analysis, for both crossover and parallel studies.

  3. Design Study: ELENA Bending Magnet Prototype

    CERN Document Server

    Schoerling, D

    2013-01-01

    The ELENA bending magnet prototype shall prove that the proposed design meets the requirements set by the ELENA beam dynamics. The following points will be discussed in detail: (i) production process of a magnetic yoke diluted with stainless steel plates, (ii) the stability and repeatability of the field homogeneity of such a yoke over the full working range, (iii) choice of soft magnetic steel, (iv) hysteresis effects, (v) mechanical deformations, (vi) thermal insulation to intercept heat load from baking for activation of NEG coating in the vacuum chamber, (vii) end shim design. In order to verify these points the following measurements will be performed: (i) Hall probe scanning, (ii) integrated field homogeneity measurement (DC), (iii) integrated field homogeneity measurement (AC).

  4. Study of the design of CSNS MEBT

    Institute of Scientific and Technical Information of China (English)

    OUYANG Hua-Fu; LIU Hua-Chang; FU Shi-Nian

    2009-01-01

    The design of CSNS MEBT has two objectives: (1) to match the beam both in the transversal direction and the longitudinal direction from RFQ into DTL; (2) to further chop the beam into the required time structure asked by RCS. It is very difficult and critical to control well the emittance growth and in the meantime to match and chop the beam. Firstly, the optical design is done and optimized, and the multi-particle simulations show that the maximum emittance growth is successfully controlled within 14%. Secondly, based on the different beam envelopes obtained by TRACE-3D and PARMELA, the least deflecting angle of the chopper is determined by TRACE-3D. At last, the field of steering magnet is determined through simulations.

  5. User Design: A Case Study on Corporate Change

    Science.gov (United States)

    Pastore, Raymond S.; Carr-Chellman, Alison A.; Lohmann, Neal

    2011-01-01

    The purpose of this study was to examine the effects of implementing user design strategies within the corporate culture. Using a case study design approach, this article explores the change process within a "Fortune" 100 company in which users were given significant decision-making powers. The main focus is on the unique nature of user design in…

  6. Study of Screen Design Principles for Visualizing Medical Records.

    Science.gov (United States)

    Fujita, Kenichiro; Takemura, Tadamasa; Kuroda, Tomohiro

    2015-01-01

    To improve UX of EMR/EHR, the screen design principles for the visualization are required. Through the study of common attributes of medical records, we present four principles and show three screen designs by applying them.

  7. Techniques for Conducting Effective Concept Design and Design-to-Cost Trade Studies

    Science.gov (United States)

    Di Pietro, David A.

    2015-01-01

    Concept design plays a central role in project success as its product effectively locks the majority of system life cycle cost. Such extraordinary leverage presents a business case for conducting concept design in a credible fashion, particularly for first-of-a-kind systems that advance the state of the art and that have high design uncertainty. A key challenge, however, is to know when credible design convergence has been achieved in such systems. Using a space system example, this paper characterizes the level of convergence needed for concept design in the context of technical and programmatic resource margins available in preliminary design and highlights the importance of design and cost evaluation learning curves in determining credible convergence. It also provides techniques for selecting trade study cases that promote objective concept evaluation, help reveal unknowns, and expedite convergence within the trade space and conveys general practices for conducting effective concept design-to-cost studies.

  8. Analytical study of recoil systems and their design

    Directory of Open Access Journals (Sweden)

    J. P. Sirpal

    1960-07-01

    Full Text Available A critical study of the various design parameters usually employed in the typical existing designs and it has been found that the order of magnitudes of some of these parameters are fairly different from those theoretically suggested. An explanation of this difference is also offered. A few additional parameters that are necessary for a preliminary design have also been studied. Based on this some considerations regarding a new design have been suggested.

  9. Reusable Reentry Satellite (RRS) system design study

    Science.gov (United States)

    1991-01-01

    The Reusable Reentry Satellite (RRS) is intended to provide investigators in several biological disciplines with a relatively inexpensive method to access space for up to 60 days with eventual recovery on Earth. The RRS will permit totally intact, relatively soft, recovery of the vehicle, system refurbishment, and reflight with new and varied payloads. The RRS is to be capable of three reflights per year over a 10-year program lifetime. The RRS vehicle will have a large and readily accessible volume near the vehicle center of gravity for the Payload Module (PM) containing the experiment hardware. The vehicle is configured to permit the experimenter late access to the PM prior to launch and rapid access following recovery. The RRS will operate in one of two modes: (1) as a free-flying spacecraft in orbit, and will be allowed to drift in attitude to provide an acceleration environment of less than 10(exp -5) g. the acceleration environment during orbital trim maneuvers will be less than 10(exp -3) g; and (2) as an artificial gravity system which spins at controlled rates to provide an artificial gravity of up to 1.5 Earth g. The RRS system will be designed to be rugged, easily maintained, and economically refurbishable for the next flight. Some systems may be designed to be replaced rather than refurbished, if cost effective and capable of meeting the specified turnaround time. The minimum time between recovery and reflight will be approximately 60 days. The PMs will be designed to be relatively autonomous, with experiments that require few commands and limited telemetry. Mass data storage will be accommodated in the PM. The hardware development and implementation phase is currently expected to start in 1991 with a first launch in late 1993.

  10. Statistical design study of lunar ceramic

    Science.gov (United States)

    Effinger, Mike; Tucker, Dennis

    1994-01-01

    Fabrication of a lunar ceramic was conducted according to a statistically designed experiment. The method of cold pressing was used since the consumption of electrical energy is kept to a minimum (a priority in the lunar environment). This traditional fabrication technique also provides an initial data source on which further investigations can be based. Results obtained from using two percent binder, a cold pressing pressure of 276 MPa, and 24 hours sintering time yielded the greatest compressive strength of 247 MPa. Analysis of each variable's influence on the compressive strength is also presented.

  11. Liquid Acquisition Device Design Sensitivity Study

    Science.gov (United States)

    VanDyke, M. K.; Hastings, L. J.

    2012-01-01

    In-space propulsion often necessitates the use of a capillary liquid acquisition device (LAD) to assure that gas-free liquid propellant is available to support engine restarts in microgravity. If a capillary screen-channel device is chosen, then the designer must determine the appropriate combination screen mesh and channel geometry. A screen mesh selection which results in the smallest LAD width when compared to any other screen candidate (for a constant length) is desirable; however, no best screen exists for all LAD design requirements. Flow rate, percent fill, and acceleration are the most influential drivers for determining screen widths. Increased flow rates and reduced percent fills increase the through-the-screen flow pressure losses, which drive the LAD to increased widths regardless of screen choice. Similarly, increased acceleration levels and corresponding liquid head pressures drive the screen mesh selection toward a higher bubble point (liquid retention capability). After ruling out some screens on the basis of acceleration requirements alone, candidates can be identified by examining screens with small flow-loss-to-bubble point ratios for a given condition (i.e., comparing screens at certain flow rates and fill levels). Within the same flow rate and fill level, the screen constants inertia resistance coefficient, void fraction, screen pore or opening diameter, and bubble point can become the driving forces in identifying the smaller flow-loss-to-bubble point ratios.

  12. Innovative Offshore Wind Plant Design Study

    Energy Technology Data Exchange (ETDEWEB)

    Hurley, William L. [Glosten Associates, Inc., Seattle, WA (United States); Nordstrom, Charles J. [Glosten Associates, Inc., Seattle, WA (United States); Morrison, Brent J. [Glosten Associates, Inc., Seattle, WA (United States)

    2013-12-18

    Technological advancements in the Glosten PelaStar floating wind turbine system have led to projected cost of energy (COE) reductions from today’s best-in-class offshore wind systems. The PelaStar system is projected to deliver a COE that is 35% lower than that delivered by the current offshore wind plants. Several technology developments have been achieved that directly target significant cost of energy reductions. These include: Application of state-of-the-art steel construction materials and methods, including fatigue-resistant welding techniques and technologies, to reduce hull steel weight; Advancements in synthetic fiber tendon design for the mooring system, which are made possible by laboratory analysis of full-scale sub-rope specimens; Investigations into selected anchor technologies to improve anchor installation methods; Refinement of the installation method, specifically through development of the PelaStar Support Barge design. Together, these technology developments drive down the capital cost and operating cost of offshore wind plants and enable access to superb wind resources in deep water locations. These technology developments also reduce the uncertainty of the PelaStar system costs, which increases confidence in the projected COE reductions.

  13. A foundational observation method for studying design situations

    DEFF Research Database (Denmark)

    Cash, Philip; Hicks, Ben; Culley, Steve

    2015-01-01

    Observational studies of designers play an important role in engineering design research, yet there is currently no accepted standard approach for comparing, combining, or contrasting studies. Consequentially, reuse, reanalysis, replication, and aggregation of data are limited and the potential...... impact of individual studies is severely constrained. This paper begins to address this issue by introducing and developing a foundational method for observational design research to improve replicability, reuse, and overall comparability of empirical studies. A three-step foundational method is proposed...

  14. Spacecraft (Mobile Satellite) configuration design study

    Science.gov (United States)

    1985-01-01

    The relative costs to procure and operate a two-satellite mobile satellite system designed to operate either in the UHF band of the L Band, and with several antenna diameter options in each frequency band was investigated. As configured, the size of the spacecraft is limited to the current RCA Series 4000 Geosynchronous Communications Spacecraft bus, which spans the range from 4000 to 5800 pounds in the transfer orbit. The Series 4000 bus forms the basis around which the Mobile Satellite transponder and associated antennas were appended. Although the resultant configuration has little outward resemblance to the present Series 4000 microwave communications spacecraft, the structure, attitude control, thermal, power, and command and control subsystems of the Series 4000 spacecraft are all adapted to support the Mobile Satellite mission.

  15. Slow cortical potential Neurofeedback and self-management training in outpatient care for children with ADHD: study protocol and first preliminary results of a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Hanna eChristiansen

    2014-11-01

    Full Text Available Background: Treatment for children with attention deficit/hyperactivity disorder (ADHD today is predominantly pharmacological. While it is the most common treatment, it might not always be the most appropriate one. Moreover, long term effects remain unclear. Behavior therapy and non-pharmacological treatments such as neurofeedback (NF are promising alternatives, though there are no routine outpatient care/effectiveness studies yet that have included children with medication or changes in medication.Methods/design: This paper presents the protocol of a randomized controlled trial to compare the effectiveness of a Slow Cortical Potential (SCP NF protocol with self-management (SM in a high frequent outpatient care setting. Both groups (NF/SM receive a total of 30 high frequent therapy sessions. Additionally, 6 sessions are reserved for comorbid problems. The primary outcome measure is the reduction of ADHD core symptoms according to parent and teacher ratings.Preliminary Results: Untill now 58 children were included in the study (48 males, with a mean age of 8.42 (1.34 years, and a mean IQ of 110 (13.37. Conners-3 parent and teacher ratings were used to estimate core symptom change. Since the study is still ongoing, and children are in different study stages, pre-post and follow-up results are not yet available for all children included. Preliminary results suggest overall good pre-post effects, though. For parent and teacher ratings an ANOVA with repeated measures yielded overall satisfying pre-post effects (η2 .175 to .513. Differences between groups (NF vs. SM could not yet be established (p = .81.Discussion: This is the first randomized controlled trial to test the effectiveness of a NF protocol in a high frequent outpatient care setting that does not exclude children on or with changes in medication. First preliminary results show positive effects. The rationale for the trial, the design, and the strengths and limitations of the study are

  16. Study of Contemporary Jewelry Design Emotional Expression Skills

    Directory of Open Access Journals (Sweden)

    Bai-hui Gong

    2017-02-01

    Full Text Available With the development of the society, people gradually realize the importance of design, design also has played a more and more important role in the life.More and more people are willing to choose the design work with unique emotions.Designers gives the new concept of life into the jewelry through the material, color, craft technique, etc. Jewelry as emotional carrier, can better deliver humanistic ideas behind the design in silence.This paper studies the emotional expression skills of contemporary jewelry design.

  17. Green Diesel from Hydrotreated Vegetable Oil Process Design Study

    NARCIS (Netherlands)

    Hilbers, T.J.; Sprakel, L.M.J.; Enk, van den L.B.J.; Zaalberg, B.; Berg, van den H.; Ham, van der A.G.J.

    2015-01-01

    A systematic approach was applied to study the process of hydrotreating vegetable oils. During the three phases of conceptual, detailed, and final design, unit operations were designed and sized. Modeling of the process was performed with UniSim Design®. Producing green diesel and jet fuel from vege

  18. Embracing Wicked Problems: The Turn to Design in Composition Studies

    Science.gov (United States)

    Marback, Richard

    2009-01-01

    Recent appeal to the concept of design in composition studies benefits teaching writing in digital media. Yet the concept of design has not been developed enough to fully benefit composition instruction. This article develops an understanding of design as a matter of resolving wicked problems and makes a case for the advantages of this…

  19. Green Diesel from Hydrotreated Vegetable Oil Process Design Study

    NARCIS (Netherlands)

    Hilbers, T.J.; Sprakel, Lisette Maria Johanna; van den Enk, L.B.J.; Zaalberg, B.; van den Berg, Henderikus; van der Ham, Aloysius G.J.

    2015-01-01

    A systematic approach was applied to study the process of hydrotreating vegetable oils. During the three phases of conceptual, detailed, and final design, unit operations were designed and sized. Modeling of the process was performed with UniSim Design®. Producing green diesel and jet fuel from

  20. Design tradeoff studies and sensitivity analysis. Appendix B

    Energy Technology Data Exchange (ETDEWEB)

    1979-05-25

    The results of the design trade-off studies and the sensitivity analysis of Phase I of the Near Term Hybrid Vehicle (NTHV) Program are presented. The effects of variations in the design of the vehicle body, propulsion systems, and other components on vehicle power, weight, cost, and fuel economy and an optimized hybrid vehicle design are discussed. (LCL)

  1. Tokamak Fusion Core Experiment: design studies based on superconducting and hybrid toroidal field coils. Design overview

    Energy Technology Data Exchange (ETDEWEB)

    Flanagan, C.A. (ed.)

    1984-10-01

    This document is a design overview that describes the scoping studies and preconceptual design effort performed in FY 1983 on the Tokamak Fusion Core Experiment (TFCX) class of device. These studies focussed on devices with all-superconducting toroidal field (TF) coils and on devices with superconducting TF coils supplemented with copper TF coil inserts located in the bore of the TF coils in the shield region. Each class of device is designed to satisfy the mission of ignition and long pulse equilibrium burn. Typical design parameters are: major radius = 3.75 m, minor radius = 1.0 m, field on axis = 4.5 T, plasma current = 7.0 MA. These designs relay on lower hybrid (LHRH) current rampup and heating to ignition using ion cyclotron range of frequency (ICRF). A pumped limiter has been assumed for impurity control. The present document is a design overview; a more detailed design description is contained in a companion document.

  2. Quasi experimental designs in pharmacist intervention research.

    Science.gov (United States)

    Krass, Ines

    2016-06-01

    Background In the field of pharmacist intervention research it is often difficult to conform to the rigorous requirements of the "true experimental" models, especially the requirement of randomization. When randomization is not feasible, a practice based researcher can choose from a range of "quasi-experimental designs" i.e., non-randomised and at time non controlled. Objective The aim of this article was to provide an overview of quasi-experimental designs, discuss their strengths and weaknesses and to investigate their application in pharmacist intervention research over the previous decade. Results In the literature quasi experimental studies may be classified into five broad categories: quasi-experimental design without control groups; quasi-experimental design that use control groups with no pre-test; quasi-experimental design that use control groups and pre-tests; interrupted time series and stepped wedge designs. Quasi-experimental study design has consistently featured in the evolution of pharmacist intervention research. The most commonly applied of all quasi experimental designs in the practice based research literature are the one group pre-post-test design and the non-equivalent control group design i.e., (untreated control group with dependent pre-tests and post-tests) and have been used to test the impact of pharmacist interventions in general medications management as well as in specific disease states. Conclusion Quasi experimental studies have a role to play as proof of concept, in the pilot phases of interventions when testing different intervention components, especially in complex interventions. They serve to develop an understanding of possible intervention effects: while in isolation they yield weak evidence of clinical efficacy, taken collectively, they help build a body of evidence in support of the value of pharmacist interventions across different practice settings and countries. However, when a traditional RCT is not feasible for

  3. The Annular Microwave Dryer Design and Study on Honeysuckle

    Directory of Open Access Journals (Sweden)

    Geng Yuefeng

    2014-03-01

    Full Text Available In order to dry fresh honeysuckle, microwave drying process were studied on fresh honeysuckle; and microwave drying apparatus on fresh honeysuckle is designed according to the drying process. The designed microwave dryer contains microwave generator, microwave dryer, dehumidifying systems, control system, transmission systems, microwave leakage inhibited mechanism and other components. The drying experiment is carried by the designed dryer, from the setting-to-work test, the design was success.

  4. Study of the Synchronous Reluctance Motor Design

    Directory of Open Access Journals (Sweden)

    Dirba J.

    2016-08-01

    Full Text Available The paper focuses on studying the external-rotor synchronous reluctance motor. The analysis is performed to estimate the influence of the number of stator slots and non-magnetic areas in the rotor (i.e., flux barriers on the electromagnetic torque and torque ripple of the studied motor. It is concluded that the increase in the number of stator slots Z = 6 to Z = 18 causes an approximately twofold decrease in the ripple factor, but torque increases by 5 %. Electromagnetic torque will be increased approximately by 24 %, if non-magnetic flux barriers are created in the rotor of the studied synchronous reluctance motor.

  5. Optimal adaptive sequential designs for crossover bioequivalence studies.

    Science.gov (United States)

    Xu, Jialin; Audet, Charles; DiLiberti, Charles E; Hauck, Walter W; Montague, Timothy H; Parr, Alan F; Potvin, Diane; Schuirmann, Donald J

    2016-01-01

    In prior works, this group demonstrated the feasibility of valid adaptive sequential designs for crossover bioequivalence studies. In this paper, we extend the prior work to optimize adaptive sequential designs over a range of geometric mean test/reference ratios (GMRs) of 70-143% within each of two ranges of intra-subject coefficient of variation (10-30% and 30-55%). These designs also introduce a futility decision for stopping the study after the first stage if there is sufficiently low likelihood of meeting bioequivalence criteria if the second stage were completed, as well as an upper limit on total study size. The optimized designs exhibited substantially improved performance characteristics over our previous adaptive sequential designs. Even though the optimized designs avoided undue inflation of type I error and maintained power at ≥ 80%, their average sample sizes were similar to or less than those of conventional single stage designs.

  6. Design Study Methodology: Reflections from the Trenches and the Stacks.

    Science.gov (United States)

    Sedlmair, M; Meyer, M; Munzner, T

    2012-12-01

    Design studies are an increasingly popular form of problem-driven visualization research, yet there is little guidance available about how to do them effectively. In this paper we reflect on our combined experience of conducting twenty-one design studies, as well as reading and reviewing many more, and on an extensive literature review of other field work methods and methodologies. Based on this foundation we provide definitions, propose a methodological framework, and provide practical guidance for conducting design studies. We define a design study as a project in which visualization researchers analyze a specific real-world problem faced by domain experts, design a visualization system that supports solving this problem, validate the design, and reflect about lessons learned in order to refine visualization design guidelines. We characterize two axes - a task clarity axis from fuzzy to crisp and an information location axis from the domain expert's head to the computer - and use these axes to reason about design study contributions, their suitability, and uniqueness from other approaches. The proposed methodological framework consists of 9 stages: learn, winnow, cast, discover, design, implement, deploy, reflect, and write. For each stage we provide practical guidance and outline potential pitfalls. We also conducted an extensive literature survey of related methodological approaches that involve a significant amount of qualitative field work, and compare design study methodology to that of ethnography, grounded theory, and action research.

  7. Study design and patient recruitment for the Japan Polyp Study

    Directory of Open Access Journals (Sweden)

    Sano Y

    2014-05-01

    , Japan Background: The Japan Polyp Study (JPS Workgroup was established in 2000 to evaluate colonoscopic follow-up surveillance strategies. The JPS was a multicenter randomized controlled trial designed to evaluate follow-up surveillance strategies in patients who had undergone two complete colonoscopies for control of colorectal cancer, with removal of all detected polyps. The aim of the present analysis was to assess the patient recruitment and whether the clinical characteristics were adequate for enrollment at the participating centers. Materials and methods: Among referrals for colonoscopy at the eleven participating centers, all patients who were 40–69 years old, without a family or personal history of familial polyposis, Lynch syndrome, inflammatory bowel disease, or a personal history of polypectomy with unknown histology, and had no invasive colorectal cancer or colectomy, were considered for inclusion from February 2003. Results: Among 4,752 referrals, a total of 3,926 patients with a mean age of 57.3 (range 40–69 years, including 2,440 (62% males, were included in the JPS. The participation rate was 83%. Among them, a total of 2,757 patients who had undergone two complete colonoscopies with removal of all detected polyps were eligible, giving an eligibility rate of 70% (2,757 of 3,926. Among the eligible patients, 2,166 were assigned to randomized groups, and 591 patients to a nonrandomized group. The last steps of data lock, analysis, and complete histopathological assessment based on a pathology review are ongoing. Conclusion: Eligible patients recruited for the JPS were successfully assigned on the basis of the expected sample-size calculation. Keywords: colonoscopy, follow-up surveillance strategies, Japan Polyp Study (JPS, study design, multicenter randomized controlled trial

  8. Research study on IPS digital controller design

    Science.gov (United States)

    Kuo, B. C.; Folkerts, C.

    1976-01-01

    The performance is investigated of the simplified continuous-data model of the Instrument Pointing System (IPS). Although the ultimate objective is to study the digital model of the system, knowledge on the performance of the continuous-data model is important in the sense that the characteristics of the digital system should approach those of the continuous-data system as the sampling period approaches zero.

  9. A warehouse design decision model: case study

    OpenAIRE

    Geraldes, Carla A. S. (Ed.); Carvalho, Maria do Sameiro; Pereira, Guilherme

    2008-01-01

    Today’s competitive and volatile market requires flexibility, quality and efficiency from the logistics operations. In this context, warehouses are an important link of the logistic chain and warehouse management plays an important role over customer's service. Throughout this work we analyze a mathematical model aiming to support warehouse management decisions. A case study is used for that purpose and the model jointly identifies product allocation to the functional areas in the warehouse, ...

  10. Design studies for the Double Chooz trigger

    Energy Technology Data Exchange (ETDEWEB)

    Cucoanes, Andi Sebastian

    2009-07-24

    The main characteristic of the neutrino mixing effect is assumed to be the coupling between the flavor and the mass eigenstates. Three mixing angles ({theta}{sub 12}, {theta}{sub 23}, {theta}{sub 13}) are describing the magnitude of this effect. Still unknown, {theta}{sub 13} is considered very small, based on the measurement done by the CHOOZ experiment. A leading experiment will be Double Chooz, placed in the Ardennes region, on the same site as used by CHOOZ. The Double Chooz goal is the exploration of {proportional_to}80% from the currently allowed {theta}{sub 13} region, by searching the disappearance of reactor antineutrinos. Double Chooz will use two similar detectors, located at different distances from the reactor cores: a near one at {proportional_to}150 m where no oscillations are expected and a far one at 1.05 km distance, close to the first minimum of the survival probability function. The measurement foresees a precise comparison of neutrino rates and spectra between both detectors. The detection mechanism is based on the inverse {beta}-decay. The Double Chooz detectors have been designed to minimize the rate of random background. In a simplified view, two optically separated regions are considered. The target, filled with Gd-doped liquid scintillator, is the main antineutrino interaction volume. Surrounding the target, the inner veto region aims to tag the cosmogenic muon background which hits the detector. Both regions are viewed by photomultipliers. The Double Chooz trigger system has to be highly efficient for antineutrino events as well as for several types of background. The trigger analyzes discriminated signals from the central region and the inner veto photomultipliers. The trigger logic is fully programmable and can combine the input signals. The trigger conditions are based on the total energy released in event and on the PMT groups multiplicity. For redundancy, two independent trigger boards will be used for the central region, each of

  11. EBTS:DESIGN AND EXPERIMENTAL STUDY.

    Energy Technology Data Exchange (ETDEWEB)

    PIKIN,A.; ALESSI,J.; BEEBE,E.; KPONOU,A.; PRELEC,K.; KUZNETSOV,G.; TIUNOV,M.

    2000-11-06

    Experimental study of the BNL Electron Beam Test Stand (EBTS), which is a prototype of the Relativistic Heavy Ion Collider (RHIC) Electron Beam Ion Source (EBIS), is currently underway. The basic physics and engineering aspects of a high current EBIS implemented in EBTS are outlined and construction of its main systems is presented. Efficient transmission of a 10 A electron beam through the ion trap has been achieved. Experimental results on generation of multiply charged ions with both continuous gas and external ion injection confirm stable operation of the ion trap.

  12. Design of Orion Soil Impact Study using the Modern Design of Experiments

    Science.gov (United States)

    DeLoach, Richard

    2010-01-01

    Two conventional One Factor At a Time (OFAT) test matrices under consideration for an Orion Landing System subscale soil impact study are reviewed. Certain weaknesses in the designs, systemic to OFAT experiment designs generally, are identified. An alternative test matrix is proposed that is based in the Modern Design of Experiments (MDOE), which achieves certain synergies by combining the original two test matrices into one. The attendant resource savings are quantified and the impact on uncertainty is discussed.

  13. Communicating Qualitative Research Study Designs to Research Ethics Review Boards

    Science.gov (United States)

    Ells, Carolyn

    2011-01-01

    Researchers using qualitative methodologies appear to be particularly prone to having their study designs called into question by research ethics or funding agency review committees. In this paper, the author considers the issue of communicating qualitative research study designs in the context of institutional research ethics review and offers…

  14. Interior Design Supports Art Education: A Case Study

    Science.gov (United States)

    Clemons, Stephanie A.

    2006-01-01

    Interior design, as a field of study, is a rapidly growing area of interest--particularly for teenagers in the United States. Part of this interest stems from the proliferation of design-related reality shows available through television media. Some art educators and curriculum specialists in the nation perceive the study of interior spaces as a…

  15. ASIPP remotely operated vehicle design (ROV) and feasibility study

    Science.gov (United States)

    Zhang, Tao; Zhang, Xuanchen; Wang, Lei; Pan, Hongtao; Zheng, Lei; Cheng, Yong; Wu, Jing

    2017-06-01

    The ROV is an important device for studying the underwater world. Thus, the ASIPP ROV is designed to meet this demand by ASIPP RH team. Through adding the wireless vision module, the performance of the robot is promoted in motion control, image collecting and so on. The rationality of the design and the effectiveness of the controller are validated by simulation and experimental study.

  16. 23 CFR 650.117 - Content of design studies.

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Content of design studies. 650.117 Section 650.117 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS...) Studies by highway agencies shall contain: (1) The hydrologic and hydraulic data and design...

  17. Interior Design Supports Art Education: A Case Study

    Science.gov (United States)

    Clemons, Stephanie A.

    2006-01-01

    Interior design, as a field of study, is a rapidly growing area of interest--particularly for teenagers in the United States. Part of this interest stems from the proliferation of design-related reality shows available through television media. Some art educators and curriculum specialists in the nation perceive the study of interior spaces as a…

  18. 300 GeV Up-dated design study

    CERN Multimedia

    1967-01-01

    The 'Report on the Design Study of a 300 GeV Proton Synchrotron' (document CERN/ 563) was issued in November 1964. An Addendum (document CERN/702) to this Design Study was issued on 30 May as one of the up-to-date set of documents and relevant costs presented to the June Council Meeting.

  19. Transitioning from Marketing-Oriented Design to User-Oriented Design: A Case Study

    Science.gov (United States)

    Laster, Shari; Stitz, Tammy; Bove, Frank J.; Wise, Casey

    2011-01-01

    The transition to a new architecture and design for an academic library Web site does not always proceed smoothly. In this case study, a library at a large research university hired an outside Web development contractor to create a new architecture and design for the university's Web site using dotCMS, an open-source content management system. The…

  20. Design Fixation and Cooperative Learning in Elementary Engineering Design Project: A Case Study

    Science.gov (United States)

    Luo, Yi

    2015-01-01

    This paper presents a case study examining 3rd, 4th and 5th graders' design fixation and cooperative learning in an engineering design project. A mixed methods instrument, the Cooperative Learning Observation Protocol (CLOP), was adapted to record frequency and class observation on cooperative learning engagement through detailed field notes.…

  1. Research designs and making causal inferences from health care studies.

    Science.gov (United States)

    Flannelly, Kevin J; Jankowski, Katherine R B

    2014-01-01

    This article summarizes the major types of research designs used in healthcare research, including experimental, quasi-experimental, and observational studies. Observational studies are divided into survey studies (descriptive and correlational studies), case-studies and analytic studies, the last of which are commonly used in epidemiology: case-control, retrospective cohort, and prospective cohort studies. Similarities and differences among the research designs are described and the relative strength of evidence they provide is discussed. Emphasis is placed on five criteria for drawing causal inferences that are derived from the writings of the philosopher John Stuart Mill, especially his methods or canons. The application of the criteria to experimentation is explained. Particular attention is given to the degree to which different designs meet the five criteria for making causal inferences. Examples of specific studies that have used various designs in chaplaincy research are provided.

  2. Beyond the castle:public space co-design, a case study and guidelines for designers

    OpenAIRE

    Cruickshank, Leon; Coupe, Gemma; Hennesy, Dee

    2013-01-01

    In this paper we describe a high profile project to reimagine a large green space in the heart of the city of Lancaster in the UK. This co-design project involved professional designers but also 2500 people with 700 of these making an active co-design contribution. This project forms the basis of a discussion of how we used a series of events to help participants reach their full creative co-design potential moving from doing to creating levels of creativity. From this case study we go on to ...

  3. Parametric design study of tandem mirror fusion reactors

    Energy Technology Data Exchange (ETDEWEB)

    Carlson, G.A.

    1977-05-27

    The parametric design study of the tandem mirror reactor (TMR) is described. The results of this study illustrate the variation of reactor characteristics with changes in the independent design parameters, reveal the set of design parameters which minimizes the cost of the reactor, and show the sensitivity of the optimized design to physics and technological uncertainties. The total direct capital cost of an optimized 1000 MWe TMR is estimated to be $1300/kWe. The direct capital cost of a 2000 MWe plant is less than $1000/kWe.

  4. Design Fixation and Cooperative Learning in Elementary Engineering Design Project: A Case Study

    Directory of Open Access Journals (Sweden)

    Yi Luo

    2015-09-01

    Full Text Available This paper presents a case study examining 3rd, 4th and 5th graders’ design fixation and cooperative learning in an engineering design project. A mixed methods instrument, the Cooperative Learning Observation Protocol (CLOP, was adapted to record frequency and class observation on cooperative learning engagement through detailed field notes. Students’ design journals and reflections were also analyzed for an inductive qualitative analysis. The findings indicate three major themes of design fixation: 1 fixation on common features of things; 2 fixation on popular teenage culture; 3 fixation on the first design idea. In the cooperative learning process of elementary engineering design project, although pupils had demonstrated some abilities to solve concrete problems in a logical fashion, the participants encountered a number of obstacles in the group. Dominance, social loafing, and other problems occurring in the group process might have offset certain benefits of cooperative learning. Implications of the findings are also discussed.

  5. Efficacy and efficiency: self-designed versus instructor-designed study tools.

    Science.gov (United States)

    Stern, E B; Hassanein, R S

    1992-03-01

    During the course of their education, occupational therapy students learn to administer complex structured assessments. For easier administration of these assessments, students design note cards, which then replace cumbersome test manuals during administration. This study considered whether students could learn test administration with equal efficiency and efficacy if given test administration note cards rather than having to design their own. The results showed that the subjects using instructor-designed cards earned written test and practical examination scores similar to those of the subjects using self-designed cards. The subjects using instructor-designed cards spent significantly less (p = .003) total time in study than did the subjects using self-designed cards. The difference in time between the two groups was attributable to the time spent designing note cards. Therefore, distribution of instructor-designed note cards appears to offer equally effective and significantly more efficient learning when compared with that produced when students design their own cards. The differences in efficacy and efficiency were similar for students of different learning styles (as classified by Witkin's field-dependence/field-independence continuum) [corrected].

  6. Advanced wind turbine design studies: Advanced conceptual study. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Hughes, P; Sherwin, R [Atlantic Orient Corp., Norwich, VT (United States)

    1994-08-01

    In conjunction with the US Department of Energy and the National Renewable Energy Laboratory`s Advanced Wind Turbine Program, the Atlantic Orient Corporation developed preliminary designs for the next generation of wind turbines. These 50 kW and 350 kW turbines are based upon the concept of simplicity. By adhering to a design philosophy that emphasizes simplicity, we project that these turbines will produce energy at extremely competitive rates which will unlock the potential of wind energy domestically and internationally. The program consisted of three distinct phases. First, we evaluated the operational history of the Enertech 44 series wind turbines. As a result of this evaluation, we developed, in the second phase, a preliminary design for a new 50 kW turbine for the near-term market. In the third phase, we took a clean-sheet-of-paper approach to designing a 350 kW turbine focused on the mid-1990s utility market that incorporated past experience and advanced technology.

  7. Research Design in the study of the European Neighbourhood Policy

    DEFF Research Database (Denmark)

    Exadaktylos, Theofanis; Lynggaard, Kennet

    2017-01-01

    This chapter deals with the pitfalls and pathways of research design aimed at the study of the European Neighbourhood Policy (ENP) and maps out the literature on questions of knowledge ambition, research ontology and epistemology, and choices of approaches to the research object. We include...... a review of traditional research designs in ENP research, through a systematic meta-analysis of a selection of the most-cited articles on the ENP. Inspired by earlier work on awareness of research design in EU studies, ENP research is categorised according to typical choices of research design in the form...... of dichotomous trade-offs. The chapter then discusses how individual contributions to this volume deal with research design challenges of the past and present innovative ways of studying the revised ENP....

  8. A Stellar Reference Unit Design Study for SIRTF

    DEFF Research Database (Denmark)

    Jørgensen, John Leif; Liebe, Carl Christian

    1996-01-01

    A design study for a stellar reference unit, or star tracker, for SIRTF was conducted in FY96 in conjunction with the Tracking Sensors Group of the Avionic Equipment Section of JPL. The resulting design was derived from the Oersted, autonomous, Advanced Stellar Compass, star tracker. The projecte...... of star tracker integration with the cryogenic telescope structure....

  9. Open Educational Resources: A Delphi Study of Instructional Design Quality

    Science.gov (United States)

    Emerson, Marnice K.

    2013-01-01

    The purpose of this modified Delphi research study was to investigate instructional designers' beliefs about the instructional strategies and activities to be included in a universal framework for designing quality, self-directed, multimedia, open educational resources (OERs). With the rapid growth of availability and use of OERs by a widely…

  10. Thinking about "Design Thinking": A Study of Teacher Experiences

    Science.gov (United States)

    Retna, Kala S.

    2016-01-01

    Schools are continuously looking for new ways of enhancing student learning to equip students with skills that would enable them to cope with twenty-first century demands. One promising approach focuses on design thinking. This study examines teacher's perceptions, experiences and challenges faced in adopting design thinking. There is a lack of…

  11. Thinking about "Design Thinking": A Study of Teacher Experiences

    Science.gov (United States)

    Retna, Kala S.

    2016-01-01

    Schools are continuously looking for new ways of enhancing student learning to equip students with skills that would enable them to cope with twenty-first century demands. One promising approach focuses on design thinking. This study examines teacher's perceptions, experiences and challenges faced in adopting design thinking. There is a lack of…

  12. An Empirical Study on Students' Ability to Comprehend Design Patterns

    Science.gov (United States)

    Chatzigeorgiou, Alexander; Tsantalis, Nikolaos; Deligiannis, Ignatios

    2008-01-01

    Design patterns have become a widely acknowledged software engineering practice and therefore have been incorporated in the curricula of most computer science departments. This paper presents an observational study on students' ability to understand and apply design patterns. Within the context of a postgraduate software engineering course,…

  13. A Stellar Reference Unit Design Study for SIRTF

    DEFF Research Database (Denmark)

    Jørgensen, John Leif; Liebe, Carl Christian

    1996-01-01

    A design study for a stellar reference unit, or star tracker, for SIRTF was conducted in FY96 in conjunction with the Tracking Sensors Group of the Avionic Equipment Section of JPL. The resulting design was derived from the Oersted, autonomous, Advanced Stellar Compass, star tracker. The projected...

  14. Pasadena City College SIGI Project Research Design. Pilot Study.

    Science.gov (United States)

    Risser, John J.; Tulley, John E.

    A pilot study evaluation of SIGI (System of Interactive Guidance and Information) at Pasadena City College in 1974-75 tested the effectiveness of an experimental research design for an expanded field test of the system the following year. (SIGI is a computer based career guidance program designed by Educational Testing Service to assist community…

  15. Lessons Learned from Applying Design Thinking in a NASA Rapid Design Study in Aeronautics

    Science.gov (United States)

    McGowan, Anna-Maria; Bakula, Casey; Castner, Raymond

    2017-01-01

    In late 2015, NASA's Aeronautics Research Mission Directorate (ARMD) funded an experiment in rapid design and rapid teaming to explore new approaches to solving challenging design problems in aeronautics in an effort to cultivate and foster innovation. This report summarizes several lessons learned from the rapid design portion of the study. This effort entailed learning and applying design thinking, a human-centered design approach, to complete the conceptual design for an open-ended design challenge within six months. The design challenge focused on creating a capability to advance experimental testing of autonomous aeronautics systems, an area of great interest to NASA, the US government as a whole, and an entire ecosystem of users and developers around the globe. A team of nine civil servant researchers from three of NASA's aeronautics field centers with backgrounds in several disciplines was assembled and rapidly trained in design thinking under the guidance of the innovation and design firm IDEO. The design thinking process, while used extensively outside the aerospace industry, is less common and even counter to many practices within the aerospace industry. In this report, several contrasts between common aerospace research and development practices and design thinking are discussed, drawing upon the lessons learned from the NASA rapid design study. The lessons discussed included working towards a design solution without a set of detailed design requirements, which may not be practical or even feasible for management to ascertain for complex, challenging problems. This approach allowed for the possibility of redesigning the original problem statement to better meet the needs of the users. Another lesson learned was to approach problems holistically from the perspective of the needs of individuals that may be affected by advances in topic area instead of purely from a technological feasibility viewpoint. The interdisciplinary nature of the design team also

  16. Transformation: Structure/space studies in bionics and space design

    Science.gov (United States)

    Gruber, Petra; Imhof, Barbara

    2007-02-01

    This paper discusses the architectural design project "Transformation Structure Space", which was carried out at the Department of Building Construction HB2 in 2004. The goal of the study was to find innovative solutions for space system design through the application of bionic (biomimetic) approaches. Using specific research both fields as the foundation, five different architectural projects based on a scientific-technological concept were developed. The introduction of natural role models into the design process and the development of the application in space and the respective setting proved to be a difficult task within the timeframe of a design program, nonetheless all of the projects show very innovative aspects.

  17. Improving Biomarker Development and Assessment: Standards for Study Design

    Institute of Scientific and Technical Information of China (English)

    Ziding FENG

    2009-01-01

    Background: The Early Detection Research Network (EDRN), NCI funded and investigator driven, has the mission to evaluate biomarkers for their clinical utilities in cancer risk prediction, diagnosis, early detection, and prognosis. Abundant cancer biomarkers reported in literature yet few are used in clinics. Therefore, the emphasis of the EDRN is biomarker validation. Although schema for a phased approach to development exists and guidelines are available for study reporting, a coherent and comprehensive set of guideline for a definitive biomarker validation study design have not been delineated.Methods: We proposed PROBE study design, Prospective specimen collec-tion and Retrospective Blinded Evaluation, for pivotal definitive evaluation of the accuracy of a classification biomarker. A detailed formulation of all aspects of the design is provided. Four tables itemize aspects that relate to (i) the Clinical Context; (ii) Performance Criteria; (iii) the Biomarker test; and (iv) Study power and termination. Alternative designs and strategies were contrasted to illustrate the merit of PROBE design.Results: The ideas are applied to studies of biomarkers the intended use of which is for disease diagnosis, screening, or prognosis. Two EDRN valida-tion studies (breast cancer and prostate cancer) were used as examples to elucidate PROBE design.Conclusion: Common biases that pervade the biomarker research literaturewould be eliminated if these rigorous standards were followed closely. We urge the adoption of the design as standard of practice for pivotal evaluation of the classification accuracy ofbiomarkers.

  18. A new design approach to innovative spectrometers. Case study: TROPOLITE

    Science.gov (United States)

    Volatier, Jean-Baptiste; Baümer, Stefan; Kruizinga, Bob; Vink, Rob

    2014-05-01

    Designing a novel optical system is a nested iterative process. The optimization loop, from a starting point to final system is already mostly automated. However this loop is part of a wider loop which is not. This wider loop starts with an optical specification and ends with a manufacturability assessment. When designing a new spectrometer with emphasis on weight and cost, numerous iterations between the optical- and mechanical designer are inevitable. The optical designer must then be able to reliably produce optical designs based on new input gained from multidisciplinary studies. This paper presents a procedure that can automatically generate new starting points based on any kind of input or new constraint that might arise. These starting points can then be handed over to a generic optimization routine to make the design tasks extremely efficient. The optical designer job is then not to design optical systems, but to meta-design a procedure that produces optical systems paving the way for system level optimization. We present here this procedure and its application to the design of TROPOLITE a lightweight push broom imaging spectrometer.

  19. Design

    DEFF Research Database (Denmark)

    Jensen, Ole B.; Pettiway, Keon

    2017-01-01

    by designers, planners, etc. (staging from above) and mobile subjects (staging from below). A research agenda for studying situated practices of mobility and mobilities design is outlined in three directions: foci of studies, methods and approaches, and epistemologies and frames of thinking. Jensen begins...... with a brief description of how movement is studied within social sciences after the “mobilities turn” versus the idea of physical movement in transport geography and engineering. He then explains how “mobilities design” was derived from connections between traffic and architecture. Jensen concludes......In this chapter, Ole B. Jensen takes a situational approach to mobilities to examine how ordinary life activities are structured by technology and design. Using “staging mobilities” as a theoretical approach, Jensen considers mobilities as overlapping, actions, interactions and decisions...

  20. Class 1 devices case studies in medical devices design

    CERN Document Server

    Ogrodnik, Peter J

    2014-01-01

    The Case Studies in Medical Devices Design series consists of practical, applied case studies relating to medical device design in industry. These titles complement Ogrodnik's Medical Device Design and will assist engineers with applying the theory in practice. The case studies presented directly relate to Class I, Class IIa, Class IIb and Class III medical devices. Designers and companies who wish to extend their knowledge in a specific discipline related to their respective class of operation will find any or all of these titles a great addition to their library. Class 1 Devices is a companion text to Medical Devices Design: Innovation from Concept to Market. The intention of this book, and its sister books in the series, is to support the concepts presented in Medical Devices Design through case studies. In the context of this book the case studies consider Class I (EU) and 510(k) exempt (FDA) . This book covers classifications, the conceptual and embodiment phase, plus design from idea to PDS. These title...

  1. A Learning and Interaction design framework, from a study on formulating principles for the design of engaging music learning games

    DEFF Research Database (Denmark)

    2012-01-01

    Based on a preliminary action research study investigating the design of digital music games and years of experiences from interaction design processes of learning resources, this extended abstract presents a framework that mixes designs for learning principles and game design with a process view...... using a simple interaction design lifecycle. Though the first outset was to design engaging music games, the resulting framework has a more generic character.......Based on a preliminary action research study investigating the design of digital music games and years of experiences from interaction design processes of learning resources, this extended abstract presents a framework that mixes designs for learning principles and game design with a process view...

  2. Initial trade and design studies for the fusion engineering device

    Energy Technology Data Exchange (ETDEWEB)

    Flanagan, C.A.; Steiner, D.; Smith, G.E.

    1981-06-01

    The Magnetic Fusion Energy Engineering Act of 1980 calls for the operation of a Fusion Engineering Device (FED) by 1990. It is the intent of the Act that the FED, in combination with other testing facilities, will establish the engineering feasibility of magnetic fusion energy. The Fusion Engineering Design Center (FEDC), under the guidance of a Technical Management Board (TMB), initiated a program of trade and design studies in October 1980 to support the selection of the FED concept. This document presents the results of these initial trade and design studies. Based on these results, a baseline configuration has been identified and the Design Center effort for the remainder of the fiscal year will be devoted to the development of a self-consistent FED design description.

  3. Design and analysis study of a spacecraft optical transceiver package

    Science.gov (United States)

    Lambert, S. G.

    1985-01-01

    A detailed system level design of an Optical Transceiver Package (OPTRANSPAC) for a deep space vehicle whose mission is outer planet exploration is developed. In addition to the terminal design, this study provides estimates of the dynamic environments to be encountered by the transceiver throughout its mission life. Optical communication link analysis, optical thin lens design, electronic functional design and mechanical layout and packaging are employed in the terminal design. Results of the study describe an Optical Transceiver Package capable of communicating to an Earth Orbiting Relay Station at a distance of 10 Astronomical Units (AU) and data rates up to 100 KBPS. The transceiver is also capable of receiving 1 KBPS of command data from the Earth Relay. The physical dimensions of the terminal are contained within a 3.5' x 1.5' x 2.0' envelope and the transceiver weight and power are estimated at 52.2 Kg (115 pounds) and 57 watts, respectively.

  4. Designing a mixed methods study in pediatric oncology nursing research.

    Science.gov (United States)

    Wilkins, Krista; Woodgate, Roberta

    2008-01-01

    Despite the appeal of discovering the different strengths of various research methods, mixed methods research remains elusive in pediatric oncology nursing research. If pediatric oncology nurses are to succeed in mixing quantitative and qualitative methods, they need practical guidelines for managing the complex data and analyses of mixed methods research. This article discusses mixed methods terminology, designs, and key design features. Specific areas addressed include the myths about mixed methods research, types of mixed method research designs, steps involved in developing a mixed method research study, and the benefits and challenges of using mixed methods designs in pediatric oncology research. Examples of recent research studies that have combined quantitative and qualitative research methods are provided. The term mixed methods research is used throughout this article to reflect the use of both quantitative and qualitative methods within one study rather than the use of these methods in separate studies concerning the same research problem.

  5. Modelling a case study in Astronomy with IMS Learning Design

    NARCIS (Netherlands)

    Burgos, Daniel; Tattersall, Colin

    2009-01-01

    Burgos, D., & Tattersall, C. (2008). Modelling a case study in Astronomy with IMS Learning Design [Electronic Version]. Journal of Interactive Media in Education, 2008 from http://jime.open.ac.uk/2008/19/.

  6. Scenario for concurrent conceptual assembly line design: A case study

    Science.gov (United States)

    Mas, F.; Ríos, J.; Menéndez, J. L.

    2012-04-01

    The decision to design and build a new aircraft is preceded by years of research and study. Different disciplines work together throughout the lifecycle to ensure not only a complete functional definition of the product, but also a complete industrialization, a marketing plan, a maintenance plan, etc. This case study focuses on the conceptual design phase. During this phase, the design solutions that will meet the functional and industrial requirements are defined, i.e.: the basic requirements of industrialization. During this phase, several alternatives are studied, and the most attractive in terms of performance and cost requirements is selected. As a result of the study of these alternatives, it is possible to define an early conceptual design of the assembly line and its basic parameters. The plant needs, long cycle jigs & tools or industrial means and human resources with the necessary skills can be determined in advance.

  7. Block 2 SRM conceptual design studies. Volume 1, Book 1: Conceptual design package

    Science.gov (United States)

    Smith, Brad; Williams, Neal; Miller, John; Ralston, Joe; Richardson, Jennifer; Moore, Walt; Doll, Dan; Maughan, Jeff; Hayes, Fred

    1986-01-01

    The conceptual design studies of a Block 2 Solid Rocket Motor (SRM) require the elimination of asbestos-filled insulation and was open to alternate designs, such as case changes, different propellants, modified burn rate - to improve reliability and performance. Limitations were placed on SRM changes such that the outside geometry should not impact the physical interfaces with other Space Shuttle elements and should have minimum changes to the aerodynamic and dynamic characteristics of the Space Shuttle vehicle. Previous Space Shuttle SRM experience was assessed and new design concepts combined to define a valid approach to assured flight success and economic operation of the STS. Trade studies, preliminary designs, analyses, plans, and cost estimates are documented.

  8. Structural Design Feasibility Study for the Global Climate Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Lewin,K.F.; Nagy, J.

    2008-12-01

    Neon, Inc. is proposing to establish a Global Change Experiment (GCE) Facility to increase our understanding of how ecological systems differ in their vulnerability to changes in climate and other relevant global change drivers, as well as provide the mechanistic basis for forecasting ecological change in the future. The experimental design was initially envisioned to consist of two complementary components; (A) a multi-factor experiment manipulating CO{sub 2}, temperature and water availability and (B) a water balance experiment. As the design analysis and cost estimates progressed, it became clear that (1) the technical difficulties of obtaining tight temperature control and maintaining elevated atmospheric carbon dioxide levels within an enclosure were greater than had been expected and (2) the envisioned study would not fit into the expected budget envelope if this was done in a partially or completely enclosed structure. After discussions between NEON management, the GCE science team, and Keith Lewin, NEON, Inc. requested Keith Lewin to expand the scope of this design study to include open-field exposure systems. In order to develop the GCE design to the point where it can be presented within a proposal for funding, a feasibility study of climate manipulation structures must be conducted to determine design approaches and rough cost estimates, and to identify advantages and disadvantages of these approaches including the associated experimental artifacts. NEON, Inc requested this design study in order to develop concepts for the climate manipulation structures to support the NEON Global Climate Experiment. This study summarizes the design concepts considered for constructing and operating the GCE Facility and their associated construction, maintenance and operations costs. Comparisons and comments about experimental artifacts, construction challenges and operational uncertainties are provided to assist in selecting the final facility design. The overall goal

  9. Identifying Appropriate Quantitative Study Designs for Library Research

    Directory of Open Access Journals (Sweden)

    Diane Lorenzetti

    2007-03-01

    Full Text Available This paper is concerned with the identification of quantitative study designs suitable for library research. Identifying a researchable question and selecting a research method best suited to it are key to the successful design and execution of any research project. Each research situation is unique, and each researcher must find the method that best suits both their situation and the question at hand. Following a brief discussion of issues related to question development, the author outlines a checklist that may assist the process of selecting study designs for quantitative research projects. When faced with options in terms of study design selection, pragmatic issues such as expertise, funding, time, and access to participants may influence this decision‐making process.

  10. Design vs. Content: A Study of Adolescent Girls' Website Design Preferences

    Science.gov (United States)

    Agosto, Denise E.

    2004-01-01

    This study considered the utility of gender schema theory in examining girls' website design preferences. It built on a previous study which identified eight website evaluation criteria related to biological sex: collaboration, social connectivity, flexibility, motility, contextuality, personal identification, inclusion, and graphic/multimedia…

  11. Methodologies and study designs relevant to medical education research.

    Science.gov (United States)

    Turner, Teri L; Balmer, Dorene F; Coverdale, John H

    2013-06-01

    Research is an important part of educational scholarship. Knowledge of research methodologies is essential for both conducting research as well as determining the soundness of the findings from published studies. Our goals for this paper therefore are to inform medical education researchers of the range and key components of educational research designs. We will discuss both qualitative and quantitative approaches to educational research. Qualitative methods will be presented according to traditions that have a distinguished history in particular disciplines. Quantitative methods will be presented according to an evidence-based hierarchy akin to that of evidence-based medicine with the stronger designs (systematic reviews and well conducted educational randomized controlled trials) at the top, and weaker designs (descriptive studies without comparison groups, or single case studies) at the bottom. It should be appreciated, however, that the research question determines the study design. Therefore, the onus is on the researcher to choose a design that is appropriate to answering the question. We conclude with an overview of how educational researchers should describe the study design and methods in order to provide transparency and clarity.

  12. Design and Experimental Study on Spinning Solid Rocket Motor

    Science.gov (United States)

    Xue, Heng; Jiang, Chunlan; Wang, Zaicheng

    The study on spinning solid rocket motor (SRM) which used as power plant of twice throwing structure of aerial submunition was introduced. This kind of SRM which with the structure of tangential multi-nozzle consists of a combustion chamber, propellant charge, 4 tangential nozzles, ignition device, etc. Grain design, structure design and prediction of interior ballistic performance were described, and problem which need mainly considered in design were analyzed comprehensively. Finally, in order to research working performance of the SRM, measure pressure-time curve and its speed, static test and dynamic test were conducted respectively. And then calculated values and experimental data were compared and analyzed. The results indicate that the designed motor operates normally, and the stable performance of interior ballistic meet demands. And experimental results have the guidance meaning for the pre-research design of SRM.

  13. Blade system design studies volume II : preliminary blade designs and recommended test matrix.

    Energy Technology Data Exchange (ETDEWEB)

    Griffin, Dayton A. (Global Energy Concepts, LLC, Kirkland, WA)

    2004-06-01

    As part of the U.S. Department of Energy's Wind Partnerships for Advanced Component Technologies (WindPACT) program, Global Energy Concepts, LLC is performing a Blade System Design Study (BSDS) concerning innovations in materials, processes and structural configurations for application to wind turbine blades in the multi-megawatt range. The BSDS Volume I project report addresses issues and constraints identified to scaling conventional blade designs to the megawatt size range, and evaluated candidate materials, manufacturing and design innovations for overcoming and improving large blade economics. The current report (Volume II), presents additional discussion of materials and manufacturing issues for large blades, including a summary of current trends in commercial blade manufacturing. Specifications are then developed to guide the preliminary design of MW-scale blades. Using preliminary design calculations for a 3.0 MW blade, parametric analyses are performed to quantify the potential benefits in stiffness and decreased gravity loading by replacement of a baseline fiberglass spar with carbon-fiberglass hybrid material. Complete preliminary designs are then presented for 3.0 MW and 5.0 MW blades that incorporate fiberglass-to-carbon transitions at mid-span. Based on analysis of these designs, technical issues are identified and discussed. Finally, recommendations are made for composites testing under Part I1 of the BSDS, and the initial planned test matrix for that program is presented.

  14. A study on the development of an infographic designer questionnaire and designer opinions

    Directory of Open Access Journals (Sweden)

    Yıldırım Serkan

    2016-01-01

    Full Text Available Technological developments and changes in how learning is understood have not only changed learning environments, but also how educational materials are developed. Infographics, one of the materials that are becoming increasingly more popular in learning environments, have nowadays become quite commonplace. Demonstrating the understanding of those who design such instructional materials is important with respect to the organisation of learning processes. In this study, we devised a questionnaire that aims to demonstrate the understanding infographic designers have of infographic design. A total of 94 students from the Department of Computer and Instructional Technologies Education of the Kazım Karabekir Faculty of Education took part in this study conducted during the fall semester of the 2013–2014 academic year. The participants were given a questionnaire consisting of 41 items that enquired about the readers’ views regarding infographic design. The collected data were assessed using Principal Component Analysis. Based on the analysis results, a questionnaire form consisting of 27 items and 8 factors (Understanding of Design, Design Process, Copyrights, Introduction, Readability, Sharing, References, Development was developed.

  15. Mining Domain-Specific Design Patterns: A Case Study

    Directory of Open Access Journals (Sweden)

    Vassiliki Gkantouna

    2017-02-01

    Full Text Available Domain-specific design patterns provide developers with proven solutions to common design problems that arise, particularly in a target application domain, facilitating them to produce quality designs in the domain contexts. However, research in this area is not mature and there are no techniques to support their detection. Towards this end, we propose a methodology which, when applied on a collection of websites in a specific domain, facilitates the automated identification of domain-specific design patterns. The methodology automatically extracts the conceptual models of the websites, which are subsequently analyzed in terms of all of the reusable design fragments used in them for supporting common domain functionalities. At the conceptual level, we consider these fragments as recurrent patterns consisting of a configuration of front-end interface components that interrelate each other and interact with end-users to support certain functionality. By performing a pattern-based analysis of the models, we locate the occurrences of all the recurrent patterns in the various website designs which are then evaluated towards their consistent use. The detected patterns can be used as building blocks in future designs, assisting developers to produce consistent and quality designs in the target domain. To support our case, we present a case study for the educational domain.

  16. Designing for Nomadic Play: A case study of participatory design with children

    DEFF Research Database (Denmark)

    Brynskov, Martin; Christensen, Bent Guldbjerg; Ludvigsen, Martin

    This poster presents the results from an empirical probe study trying to engage children creatively in the design process of systems and artifacts that support nomadic life-style. Based on observational studies and interviews with children of different ages (5-15 years), we conducted...... a participatory design workshop cycle where children were encouraged to envision and virtually play with not-yet-invented future technology. Findings include qualitative characterizations of children’s activities (e.g. ‘play’ culture, use of digital media, age and gender differences, relation to space...

  17. Acting like a physicist: Student approach study to experimental design

    Science.gov (United States)

    Karelina, Anna; Etkina, Eugenia

    2007-12-01

    National studies of science education have unanimously concluded that preparing our students for the demands of the 21st century workplace is one of the major goals. This paper describes a study of student activities in introductory college physics labs, which were designed to help students acquire abilities that are valuable in the workplace. In these labs [called Investigative Science Learning Environment (ISLE) labs], students design their own experiments. Our previous studies have shown that students in these labs acquire scientific abilities such as the ability to design an experiment to solve a problem, the ability to collect and analyze data, the ability to evaluate assumptions and uncertainties, and the ability to communicate. These studies mostly concentrated on analyzing students’ writing, evaluated by specially designed scientific ability rubrics. Recently, we started to study whether the ISLE labs make students not only write like scientists but also engage in discussions and act like scientists while doing the labs. For example, do students plan an experiment, validate assumptions, evaluate results, and revise the experiment if necessary? A brief report of some of our findings that came from monitoring students’ activity during ISLE and nondesign labs was presented in the Physics Education Research Conference Proceedings. We found differences in student behavior and discussions that indicated that ISLE labs do in fact encourage a scientistlike approach to experimental design and promote high-quality discussions. This paper presents a full description of the study.

  18. Studying time to pregnancy by use of a retrospective design

    DEFF Research Database (Denmark)

    Joffe, Michael; Key, Jane; Best, Nicky

    2005-01-01

    Biologic fertility can be measured using time to pregnancy (TTP). Retrospective designs, although lacking detailed timed information about behavior and exposure, are useful since they have a well-defined target population, often have good response rates, and are simpler and less expensive...... at the beginning of unprotected intercourse. More complete inference is possible if the study design covers the whole population, not just those who achieve a pregnancy....

  19. Design Study for a Low-Distortion Holographic HUD.

    Science.gov (United States)

    1982-01-01

    HUD W.S. Colburn, R.C. Fairchild RADAR AND OPTICS DIVISION ENVIRONMENTAL RESEARCH INSTITUTE OF MICHIGAN P.O. Box 8618, Ann Arbor, Michigan 48107...When Data Entered) l "Diffraction Optics Design Study" FOREWORD This report was prepared by the Electro-Optics Depart- ment, Radar and Optics...where the ray directions are reversed by the raytrace program. This design resulted in a combiner with a focal length of 193 mm, and which is predicted

  20. 5 MW pulsed spallation neutron source, Preconceptual design study

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    This report describes a self-consistent base line design for a 5 MW Pulsed Spallation Neutron Source (PSNS). It is intended to establish feasibility of design and as a basis for further expanded and detailed studies. It may also serve as a basis for establishing project cost (30% accuracy) in order to intercompare competing designs for a PSNS not only on the basis of technical feasibility and technical merit but also on the basis of projected total cost. The accelerator design considered here is based on the objective of a pulsed neutron source obtained by means of a pulsed proton beam with average beam power of 5 MW, in {approx} 1 {mu}sec pulses, operating at a repetition rate of 60 Hz. Two target stations are incorporated in the basic facility: one for operation at 10 Hz for long-wavelength instruments, and one operating at 50 Hz for instruments utilizing thermal neutrons. The design approach for the proton accelerator is to use a low energy linear accelerator (at 0.6 GeV), operating at 60 Hz, in tandem with two fast cycling booster synchrotrons (at 3.6 GeV), operating at 30 Hz. It is assumed here that considerations of cost and overall system reliability may favor the present design approach over the alternative approach pursued elsewhere, whereby use is made of a high energy linear accelerator in conjunction with a dc accumulation ring. With the knowledge that this alternative design is under active development, it was deliberately decided to favor here the low energy linac-fast cycling booster approach. Clearly, the present design, as developed here, must be carried to the full conceptual design stage in order to facilitate a meaningful technology and cost comparison with alternative designs.

  1. FEL Design Studies at LBNL: Activities and Plans

    Energy Technology Data Exchange (ETDEWEB)

    Corlett, John N.; Fawley, W.; Lidia, S.; Padmore, H.; Penn, G.; Pogorelov, I.; Qiang, J.; Sannibale, F.; Staples, J.; Steier, C.; Venturini, M.; Wan, W.; Wilcox, R.; Zholents, A.

    2007-03-01

    LBNL staff are currently pursuing R&D for future x-ray FELs, and participate in two FEL construction projects. Our strategy is to address the most fundamental challenges, which are the cost-drivers and performance limitations of FEL facilities. An internally funded R&D program is aimed at investigating accelerator physics and technologies in three key areas: (1) Theoretical study, modeling, and experimental development of low emittance, high quantum efficiency cathodes; (2) Design studies of electron beam delivery systems, including emittance manipulations, high-resolution modeling of 6-D phase space, and low-emittance beam transport; and (3) Design studies of optical manipulations of electron beams for seeded and SASE FELs, providing short x-ray pulses of variable duration, synchronous with the seed and pump laser sources, and also long transform-limited pulses with a narrow bandwidth. Design studies of means for production of attosecond x-ray pulses at various wavelengths. We are collaborators in the FERMI{at}Elettra seeded FEL facility under construction at Sincrotrone Trieste, Italy, participating in accelerator design and FEL physics studies, and mechanical and electrical engineering. We are participating in the LCLS project at SLAC, implementing our design of stabilized timing and synchronization systems. Here we outline our long-term objectives, and current activities.

  2. The Aesthetics of Sundanese Traditional Design, Case study: Rice Containers Design

    Directory of Open Access Journals (Sweden)

    Jamaludin Jamaludin

    2014-10-01

    Full Text Available The traditional design that is still made and exists today is a legacy from mythical culture period. That is to say that it has its own aesthetical concept that is different from modern aesthetics. Some of the traditional designs in Sundanese society is the rice containers that come in different form depends on the rice condition. The design of a traditional rice container in Sundanese culture is made in basic shapes, such as square, circle and triangle or configuration of the basic shapes resulted in a beautiful design. The rice containers mostly made of woven bamboo. Uniquely, these visual basic shapes also found in proverbs and idioms in Sundanese language as a symbol of perfection of conduct.  Square symbolizes attitude or behavior, circle is for belief or faith, and triangle represents a holy place. Rice in traditional community such as Baduy in Banten has a connection with the myth of the goddess of rice. Thus, Sundanese traditional culture and society highly respect the rice. This is one of the reasons why the traditional rice containers are designed in those form. This study has come to a conclusion that traditional design made is not merely to fulfill utility needs but also to represent the Sundanese macrocosm.

  3. Designing A Mixed Methods Study In Primary Care

    OpenAIRE

    Creswell, John W.; Fetters, Michael D.; Ivankova, Nataliya V.

    2004-01-01

    BACKGROUND Mixed methods or multimethod research holds potential for rigorous, methodologically sound investigations in primary care. The objective of this study was to use criteria from the literature to evaluate 5 mixed methods studies in primary care and to advance 3 models useful for designing such investigations.

  4. Experiences of Computer Science Curriculum Design: A Phenomenological Study

    Science.gov (United States)

    Sloan, Arthur; Bowe, Brian

    2015-01-01

    This paper presents a qualitative study of 12 computer science lecturers' experiences of curriculum design of several degree programmes during a time of transition from year-long to semesterised courses, due to institutional policy change. The background to the study is outlined, as are the reasons for choosing the research methodology. The main…

  5. The Design of the Junior High Management Improvement Study.

    Science.gov (United States)

    Emmer, Edmund T.; And Others

    This report provides a description of the experimental design, including the procedures, instrumentation, and sample, of the Junior High School Management Improvement Study. The research leading up to this study is briefly described along with the conceptualization of the management function of teaching and the development of training manuals for…

  6. Designing A Mixed Methods Study In Primary Care

    OpenAIRE

    Creswell, John W.; Fetters, Michael D.; Ivankova, Nataliya V.

    2004-01-01

    BACKGROUND Mixed methods or multimethod research holds potential for rigorous, methodologically sound investigations in primary care. The objective of this study was to use criteria from the literature to evaluate 5 mixed methods studies in primary care and to advance 3 models useful for designing such investigations.

  7. Design science research as research approach in doctoral studies

    CSIR Research Space (South Africa)

    Kotzé, P

    2015-08-01

    Full Text Available Since the use of design science research (DSR) gained momentum as a research approach in information systems (IS), the adoption of a DSR approach in postgraduate studies became more acceptable. This paper reflects on a study to investigate how a...

  8. Empirical evidence of study design biases in randomized trials

    DEFF Research Database (Denmark)

    Page, Matthew J.; Higgins, Julian P. T.; Clayton, Gemma

    2016-01-01

    Objective: To synthesise evidence on the average bias and heterogeneity associated with reported methodological features of randomized trials. Design: Systematic review of meta-epidemiological studies. Methods: We retrieved eligible studies included in a recent AHRQ-EPC review on this topic (late...

  9. Experiences of Computer Science Curriculum Design: A Phenomenological Study

    Science.gov (United States)

    Sloan, Arthur; Bowe, Brian

    2015-01-01

    This paper presents a qualitative study of 12 computer science lecturers' experiences of curriculum design of several degree programmes during a time of transition from year-long to semesterised courses, due to institutional policy change. The background to the study is outlined, as are the reasons for choosing the research methodology. The main…

  10. Design studies for twist-coupled wind turbine blades.

    Energy Technology Data Exchange (ETDEWEB)

    Valencia, Ulyses (Wichita State University, Wichita, KS); Locke, James (Wichita State University, Wichita, KS)

    2004-06-01

    This study presents results obtained for four hybrid designs of the Northern Power Systems (NPS) 9.2-meter prototype version of the ERS-100 wind turbine rotor blade. The ERS-100 wind turbine rotor blade was designed and developed by TPI composites. The baseline design uses e-glass unidirectional fibers in combination with {+-}45-degree and random mat layers for the skin and spar cap. This project involves developing structural finite element models of the baseline design and carbon hybrid designs with and without twist-bend coupling. All designs were evaluated for a unit load condition and two extreme wind conditions. The unit load condition was used to evaluate the static deflection, twist and twist-coupling parameter. Maximum deflections and strains were determined for the extreme wind conditions. Linear and nonlinear buckling loads were determined for a tip load condition. The results indicate that carbon fibers can be used to produce twist-coupled designs with comparable deflections, strains and buckling loads to the e-glass baseline.

  11. Preliminary design study of the TMT Telescope structure system: overview

    Science.gov (United States)

    Usuda, Tomonori; Ezaki, Yutaka; Kawaguchi, Noboru; Nagae, Kazuhiro; Kato, Atsushi; Takaki, Junji; Hirano, Masaki; Hattori, Tomoya; Tabata, Masaki; Horiuchi, Yasushi; Saruta, Yusuke; Sofuku, Satoru; Itoh, Noboru; Oshima, Takeharu; Takanezawa, Takashi; Endo, Makoto; Inatani, Junji; Iye, Masanori; Sadjadpour, Amir; Sirota, Mark; Roberts, Scott; Stepp, Larry

    2014-07-01

    We present an overview of the preliminary design of the Telescope Structure System (STR) of Thirty Meter Telescope (TMT). NAOJ was given responsibility for the TMT STR in early 2012 and engaged Mitsubishi Electric Corporation (MELCO) to take over the preliminary design work. MELCO performed a comprehensive preliminary design study in 2012 and 2013 and the design successfully passed its Preliminary Design Review (PDR) in November 2013 and April 2014. Design optimizations were pursued to better meet the design requirements and improvements were made in the designs of many of the telescope subsystems as follows: 1. 6-legged Top End configuration to support secondary mirror (M2) in order to reduce deformation of the Top End and to keep the same 4% blockage of the full aperture as the previous STR design. 2. "Double Lower Tube" of the elevation (EL) structure to reduce the required stroke of the primary mirror (M1) actuators to compensate the primary mirror cell (M1 Cell) deformation caused during the EL angle change in accordance with the requirements. 3. M1 Segment Handling System (SHS) to be able to make removing and installing 10 Mirror Segment Assemblies per day safely and with ease over M1 area where access of personnel is extremely difficult. This requires semi-automatic sequence operation and a robotic Segment Lifting Fixture (SLF) designed based on the Compliance Control System, developed for controlling industrial robots, with a mechanism to enable precise control within the six degrees of freedom of position control. 4. CO2 snow cleaning system to clean M1 every few weeks that is similar to the mechanical system that has been used at Subaru Telescope. 5. Seismic isolation and restraint systems with respect to safety; the maximum acceleration allowed for M1, M2, tertiary mirror (M3), LGSF, and science instruments in 1,000 year return period earthquakes are defined in the requirements. The Seismic requirements apply to any EL angle, regardless of the

  12. Parametric design of the Vela roof: A case study on performance oriented exploration of design alternatives

    NARCIS (Netherlands)

    Turrin, M.; Stouffs, R.M.F.; Sariyildiz, I.S.

    2010-01-01

    The paper presents a case study, in which parametric modeling has been used to explore the geometrical design alternatives of a large span roof. Explorative criteria are oriented to the use of on site energy resources, with specific focus on the mitigation of summer discomfort. After broadly

  13. Preliminary Design of a Modular Unmanned Research Vehicle. Volume 2. Subsystem Technical Development Design Study

    Science.gov (United States)

    1988-12-01

    for real-time analysis, or post-test aaalvsis innaediate;y foliowing the tesi , in a form that was iure easily interpreted. Because the test site will...in the baseline MURV design is the Teledyne 320. 11.6.2.4 Fuel Loading Trade Study With the propulsion system characteristics de- cided , the optimal

  14. Design Core Commonalities: A Study of the College of Design at Iowa State University

    Science.gov (United States)

    Venes, Jane

    2015-01-01

    This comprehensive study asks what a group of rather diverse disciplines have in common. It involves a cross-disciplinary examination of an entire college, the College of Design at Iowa State University. This research was intended to provide a sense of direction in developing and assessing possible core content. The reasoning was that material…

  15. Sustainable Innovation for Queensland's Housing Design: a Case Study

    Directory of Open Access Journals (Sweden)

    Michael Johnston

    2014-12-01

    Full Text Available This research provides an assessment tool that assists the selection process of sustainability in detached suburban housing. It investigates the implications of using different design and construction methods including architecturally designed houses, developer housing and prefabricated houses. The study simulates one example of the three types of houses that have been chosen to fulfil a real client brief on a real site on the Sunshine Coast, Queensland Australia. Criteria for sustainability assessment are formulated based on literature reviews, exemplar designs and similar research projects for which the houses can be adequately evaluated. This criterion covers aspects including energy use, materials and thermal performance. The data is collected using computer models and sustainability assessment software to compare and draw conclusions on the success of each house.Our study indicates that architecturally designed housing with prefabricated building techniques are a better alternative to generic developer style housing. Our research provides an insight into the implications of three key elements of sustainability including energy use, materials and thermal performance. Designers, builders, developers and home-buyers are given an insight into some options currently available on the housing market and how the choices made during early design stages can provide a more positive environmental impact.  

  16. Sustainable Innovation for Queensland's Housing Design: a Case Study

    Directory of Open Access Journals (Sweden)

    Michael Johnston

    2014-12-01

    Full Text Available This research provides an assessment tool that assists the selection process of sustainability in detached suburban housing. It investigates the implications of using different design and construction methods including architecturally designed houses, developer housing and prefabricated houses. The study simulates one example of the three types of houses that have been chosen to fulfil a real client brief on a real site on the Sunshine Coast, Queensland Australia. Criteria for sustainability assessment are formulated based on literature reviews, exemplar designs and similar research projects for which the houses can be adequately evaluated. This criterion covers aspects including energy use, materials and thermal performance. The data is collected using computer models and sustainability assessment software to compare and draw conclusions on the success of each house. Our study indicates that architecturally designed housing with prefabricated building techniques are a better alternative to generic developer style housing. Our research provides an insight into the implications of three key elements of sustainability including energy use, materials and thermal performance. Designers, builders, developers and home-buyers are given an insight into some options currently available on the housing market and how the choices made during early design stages can provide a more positive environmental impact.

  17. The Danish Alzheimer Intervention Study: Rationale, Study Design and Baseline Characteristics of the Cohort

    DEFF Research Database (Denmark)

    Waldemar, G.; Waldorff, F.B.; Buss, D.V.

    2011-01-01

    There is a lack of appropriately designed trials investigating the efficacy of psychosocial interventions for patients with mild dementia and their family caregivers. This paper reports the rationale and design of the Danish Alzheimer Disease Intervention Study and baseline characteristics...

  18. Improving Creativity Training: A Study of Designer Skills

    DEFF Research Database (Denmark)

    Valgeirsdóttir, Dagný; Onarheim, Balder; Li-Ying, Jason

    2016-01-01

    and Cross2001]. Establishing that creativity is important for design and innovation implies that identifying ways of improving creativity is a relevant research area within design studies. Creativity is a basic human skill and multiple studies have been published showing that creativity is a skill that can...... be trained (see e.g.[Scott et al. 2004] for a review of these). Despite establishing that creativity training works, it is though not yet clear how individual creativity skills can influence the creative process, although many studieshave been published on different types of creativity training formats e.......g. [Scott et al. 2004], [Robbinsand Kegley 2010]. The aim of this study was therefore to investigate how individual creativity skills influence the creative process of design teams working within the fuzzy front end (as defined in [Koenet al. 2002]) of innovation; an important first step in identifying...

  19. The FCC-ee design study: luminosity and beam polarization

    CERN Document Server

    Koratzinos, M

    2015-01-01

    The FCC-ee accelerator is considered within the FCC design study as a possible first step towards the ultimate goal of a 100 TeV hadron collider. It is a high luminosity e+e- storage ring collider, designed to cover energies of around 90, 160, 240 and 350GeV ECM (for the Z peak, the WW threshold, the ZH and ttbar cross-section maxima respectively) leading to different operating modes. We report on the current status of the design study, on the most promising concepts and relevant challenges. The expected luminosity performance at all energies, and first studies on transverse polarization for beam energy calibrations will be presented.

  20. Integrated source and channel encoded digital communication system design study

    Science.gov (United States)

    Alem, W. K.; Huth, G. K.; Simon, M. K.

    1978-01-01

    The particular Ku-band carrier, PN despreading, and symbol synchronization strategies, which were selected for implementation in the Ku-band transponder aboard the orbiter, were assessed and evaluated from a systems performance viewpoint, verifying that system specifications were met. A study was performed of the design and implementation of tracking techniques which are suitable for incorporation into the Orbiter Ku-band communication system. Emphasis was placed on maximizing tracking accuracy and communication system flexibility while minimizing cost, weight, and system complexity of Orbiter and ground systems hardware. The payload communication study assessed the design and performance of the forward link and return link bent-pipe relay modes for attached and detached payloads. As part of this study, a design for a forward link bent-pipe was proposed which employs a residual carrier but which is tracked by the existing Costas loop.

  1. code_swarm: a design study in organic software visualization.

    Science.gov (United States)

    Ogawa, Michael; Ma, Kwan-Liu

    2009-01-01

    In May of 2008, we published online a series of software visualization videos using a method called code_swarm. Shortly thereafter, we made the code open source and its popularity took off. This paper is a study of our code swarm application, comprising its design, results and public response. We share our design methodology, including why we chose the organic information visualization technique, how we designed for both developers and a casual audience, and what lessons we learned from our experiment. We validate the results produced by code_swarm through a qualitative analysis and by gathering online user comments. Furthermore, we successfully released the code as open source, and the software community used it to visualize their own projects and shared their results as well. In the end, we believe code_swarm has positive implications for the future of organic information design and open source information visualization practice.

  2. Studying visual and spatial reasoning for design creativity

    CERN Document Server

    2015-01-01

    Creativity and design creativity in particular are being recognized as playing an increasing role in the social and economic wellbeing of a society. As a consequence creativity is becoming a focus of research. However, much of this burgeoning research is distributed across multiple disciplines that normally do not intersect with each other and researchers in one discipline are often unaware of related research in another discipline.  This volume brings together contributions from design science, computer science, cognitive science and neuroscience on studying visual and spatial reasoning applicable to design creativity. The book is the result of a unique NSF-funded workshop held in Aix-en-Provence, France. The aim of the workshop and the resulting volume was to allow researchers in disparate disciplines to be exposed to the other’s research, research methods and research results within the context of design creativity. Fifteen of the papers presented and discussed at the workshop are contained in this volu...

  3. Design Study Of Cyclotron Magnet With Permanent Magnet

    Science.gov (United States)

    Kim, Hyun Wook; Chai, Jong Seo

    2011-06-01

    Low energy cyclotrons for Positron emission tomography (PET) have been wanted for the production of radio-isotopes after 2002. In the low energy cyclotron magnet design, increase of magnetic field between the poles is needed to make a smaller size of magnet and decrease power consumption. The Permanent magnet can support this work without additional electric power consumption in the cyclotron. In this paper the study of cyclotron magnet design using permanent magnet is shown and also the comparison between normal magnet and the magnet which is designed with permanent magnet is shown. Maximum energy of proton is 8 MeV and RF frequency is 79.3 MHz. 3D CAD design was done by CATIA P3 V5 R18 [1] and the All field calculations had been performed by OPERA-3D TOSCA [2]. The self-made beam dynamics program OPTICY [3] is used for making isochronous field and other calculations.

  4. Gas recombination device design and cost study. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1980-07-01

    Under a contract with Argonne National Laboratory, VARTA Batterie AG. conducted a design and cost study of hydrogen-oxygen recombination devices (HORD) for use with utility load-leveling lead-acid cells. Design specifications for the devices, through extensive calculation of the heat-flow conditions of the unit, were developed. Catalyst and condenser surface areas were specified. The exact dimensions can, however, be adjusted to the cell dimension and the space available above the cell. Design specifications were also developed for additional components required to ensure proper function of the recombination device, including metal hydride compound decomposer, aerosol retainer, and gas storage component. Costs for HORD were estimated to range from $4 to $10/kWh cell capacity for the production of a large number of units (greater than or equal to 10,000 units). The cost is a function of cell size and positive grid design. 21 figures, 2 tables.

  5. High performance APCS conceptual design and evaluation scoping study

    Energy Technology Data Exchange (ETDEWEB)

    Soelberg, N.; Liekhus, K.; Chambers, A.; Anderson, G.

    1998-02-01

    This Air Pollution Control System (APCS) Conceptual Design and Evaluation study was conducted to evaluate a high-performance (APC) system for minimizing air emissions from mixed waste thermal treatment systems. Seven variations of high-performance APCS designs were conceptualized using several design objectives. One of the system designs was selected for detailed process simulation using ASPEN PLUS to determine material and energy balances and evaluate performance. Installed system capital costs were also estimated. Sensitivity studies were conducted to evaluate the incremental cost and benefit of added carbon adsorber beds for mercury control, specific catalytic reduction for NO{sub x} control, and offgas retention tanks for holding the offgas until sample analysis is conducted to verify that the offgas meets emission limits. Results show that the high-performance dry-wet APCS can easily meet all expected emission limits except for possibly mercury. The capability to achieve high levels of mercury control (potentially necessary for thermally treating some DOE mixed streams) could not be validated using current performance data for mercury control technologies. The engineering approach and ASPEN PLUS modeling tool developed and used in this study identified APC equipment and system performance, size, cost, and other issues that are not yet resolved. These issues need to be addressed in feasibility studies and conceptual designs for new facilities or for determining how to modify existing facilities to meet expected emission limits. The ASPEN PLUS process simulation with current and refined input assumptions and calculations can be used to provide system performance information for decision-making, identifying best options, estimating costs, reducing the potential for emission violations, providing information needed for waste flow analysis, incorporating new APCS technologies in existing designs, or performing facility design and permitting activities.

  6. Japan Diabetic Nephropathy Cohort Study: study design, methods, and implementation.

    Science.gov (United States)

    Furuichi, Kengo; Shimizu, Miho; Toyama, Tadashi; Koya, Daisuke; Koshino, Yoshitaka; Abe, Hideharu; Mori, Kiyoshi; Satoh, Hiroaki; Imanishi, Masahito; Iwano, Masayuki; Yamauchi, Hiroyuki; Kusano, Eiji; Fujimoto, Shouichi; Suzuki, Yoshiki; Okuda, Seiya; Kitagawa, Kiyoki; Iwata, Yasunori; Kaneko, Shuichi; Nishi, Shinichi; Yokoyama, Hitoshi; Ueda, Yoshihiko; Haneda, Masakazu; Makino, Hirofumi; Wada, Takashi

    2013-12-01

    Diabetic nephropathy, leading to end-stage renal disease, has a considerable impact on public health and the social economy. However, there are few national registries of diabetic nephropathy in Japan. The aims of this prospective cohort study are to obtain clinical data and urine samples for revising the clinical staging of diabetic nephropathy, and developing new diagnostic markers for early diabetic nephropathy. The Japanese Society of Nephrology established a nationwide, web-based, and prospective registry system. On the system, there are two basic registries; the Japan Renal Biopsy Registry (JRBR), and the Japan Kidney Disease Registry (JKDR). In addition to the two basic registries, we established a new prospective registry to the system; the Japan Diabetic Nephropathy Cohort Study (JDNCS), which collected physical and laboratory data. We analyzed the data of 321 participants (106 female, 215 male; average age 65 years) in the JDNCS. Systolic and diastolic blood pressure was 130.1 and 72.3 mmHg, respectively. Median estimated glomerular filtration rate (eGFR) was 33.3 ml/min/1.73 m(2). Proteinuria was 1.8 g/gCr, and serum levels of albumin were 3.6 g/dl. The majority of the JDNCS patients presented with preserved eGFR and low albuminuria or low eGFR and advanced proteinuria. In the JRBR and JKDR registries, 484 and 125 participants, respectively, were enrolled as having diabetes mellitus. In comparison with the JRBR and JKDR registries, the JDNCS was characterized by diabetic patients presenting with low proteinuria with moderately preserved eGFR. There are few national registries of diabetic nephropathy to evaluate prognosis in Japan. Future analysis of the JDNCS will provide clinical insights into the epidemiology and renal and cardiovascular outcomes of type 2 diabetic patients in Japan.

  7. Aircraft energy efficiency laminar flow control wing design study

    Science.gov (United States)

    Bonner, T. F., Jr.; Pride, J. D., Jr.; Fernald, W. W.

    1977-01-01

    An engineering design study was performed in which laminar flow control (LFC) was integrated into the wing of a commercial passenger transport aircraft. A baseline aircraft configuration was selected and the wing geometry was defined. The LFC system, with suction slots, ducting, and suction pumps was integrated with the wing structure. The use of standard aluminum technology and advanced superplastic formed diffusion bonded titanium technology was evaluated. The results of the design study show that the LFC system can be integrated with the wing structure to provide a structurally and aerodynamically efficient wing for a commercial transport aircraft.

  8. Study on the Application of C Language in Menu Design

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    This paper studies the application of C language graphic function in the computer design process through a practical example of menu design using C language. It consists of three main modules:the instruction of self-definition function used in the process of initialization of screen and menu system, the instruction of ini tialization screen and menu system, and the instruction of self-definition function used in keyboard service program. The study reveals the properties of abundance and practice of the library function of C language.

  9. The cardiac insufficiency talinolol study (CITAS) study design.

    Science.gov (United States)

    Campeanu, A

    2001-06-01

    Beta-blockers without partial agonist activity are now considered to be strategic therapy for patients with chronic heart failure, but many issues remain to be clarified. The objective of the double-blind, randomized, placebo-controlled cardiac insufficiency talinolol study (CITAS) is to assess efficacy and safety of talinolol - a selective beta-1 adrenoreceptor blocker - in patients with ischemic and non-ischemic heart failure. The primary end-point refers to the influence of talinolol on exercise capacity, evaluated by 6-min walking-test. Secondary end-points consist of left ventricular function, cardiovascular and all-cause mortality, hospitalizations, quality of life, combined clinical end-points and adverse events. There were enrolled 294 patients with stable heart failure in NYHA class II-IV, LVEF <40%, receiving diuretics, ACE-inhibitors and optionally nitrates and digoxin. Talinolol was titrated up to 100 mg/day (one arm) or to 150 mg/d (the other arm), starting with 12.5 mg daily. Enrollment began in November 1997 and the last visit will be in December 2000.

  10. Design and analysis issues in gene and environment studies

    Directory of Open Access Journals (Sweden)

    Liu Chen-yu

    2012-12-01

    Full Text Available Abstract Both nurture (environmental and nature (genetic factors play an important role in human disease etiology. Traditionally, these effects have been thought of as independent. This perspective is ill informed for non-mendelian complex disorders which result as an interaction between genetics and environment. To understand health and disease we must study how nature and nurture interact. Recent advances in human genomics and high-throughput biotechnology make it possible to study large numbers of genetic markers and gene products simultaneously to explore their interactions with environment. The purpose of this review is to discuss design and analytic issues for gene-environment interaction studies in the “-omics” era, with a focus on environmental and genetic epidemiological studies. We present an expanded environmental genomic disease paradigm. We discuss several study design issues for gene-environmental interaction studies, including confounding and selection bias, measurement of exposures and genotypes. We discuss statistical issues in studying gene-environment interactions in different study designs, such as choices of statistical models, assumptions regarding biological factors, and power and sample size considerations, especially in genome-wide gene-environment studies. Future research directions are also discussed.

  11. Novel Hyper-Redundant Manipulator: Design, Study and Experiment

    Institute of Scientific and Technical Information of China (English)

    李彦明; 马培荪; 秦昌俊; 曹志奎; 王建滨; 朱海鸿

    2003-01-01

    A novel hyper-redundant manipulator named RT1 is designed and studied.The unique feature of RT1 is all degrees of freedom (DOF) are actuated with only one motor via special designed hinge bar universal joints.The mechanisms of RT1 are introduced in detail.Some experiments are carried out in order to test the movability and adaptability of the manipulator.RT1 is actuated by pulse string and acts discretely.The discrete working space of RT1 is described and the parameter optimization for kinematical redundancy resolution is studied also.The optimization criterion is altering the design parameter as little as possible during manipulator's motion from the initial position to the expected position.An[1] optimization example is given that is realized with Matlab optimize tool-box.

  12. Influence analysis on crossover design experiment in bioequivalence studies.

    Science.gov (United States)

    Huang, Yufen; Ke, Bo-Shiang

    2014-01-01

    Crossover designs are commonly used in bioequivalence studies. However, the results can be affected by some outlying observations, which may lead to the wrong decision on bioequivalence. Therefore, it is essential to investigate the influence of aberrant observations. Chow and Tse in 1990 discussed this issue by considering the methods based on the likelihood distance and estimates distance. Perturbation theory provides a useful tool for the sensitivity analysis on statistical models. Hence, in this paper, we develop the influence functions via the perturbation scheme proposed by Hampel as an alternative approach on the influence analysis for a crossover design experiment. Moreover, the comparisons between the proposed approach and the method proposed by Chow and Tse are investigated. Two real data examples are provided to illustrate the results of these approaches. Our proposed influence functions show excellent performance on the identification of outlier/influential observations and are suitable for use with small sample size crossover designs commonly used in bioequivalence studies.

  13. Design study of the KIRAMS-430 superconducting cyclotron magnet

    Science.gov (United States)

    Kim, Hyun Wook; Kang, Joonsun; Hong, Bong Hwan; Jung, In Su

    2016-07-01

    Design study of superconducting cyclotron magnet for the carbon therapy was performed at the Korea Institute of Radiological and Medical Science (KIRAMS). The name of this project is The Korea Heavy Ion Medical Accelerator (KHIMA) project and a fixed frequency cyclotron with four spiral sector magnet was one of the candidate for the accelerator type. Basic parameters of the cyclotron magnet and its characteristics were studied. The isochronous magnetic field which can guide the 12C6+ ions up to 430 MeV/u was designed and used for the single particle tracking simulation. The isochronous condition of magnetic field was achieved by optimization of sector gap and width along the radius. Operating range of superconducting coil current was calculated and changing of the magnetic field caused by mechanical deformations of yokes was considered. From the result of magnetic field design, structure of the magnet yoke was planned.

  14. [Introduction to critical reading of articles: study design and biases].

    Science.gov (United States)

    García Villar, C

    2015-01-01

    The critical evaluation of an article enables professionals to make good use of the new information and therefore has direct repercussions for the benefit of our patients. Before undertaking a detailed critical reading of the chosen article, we need to consider whether the study used the most appropriate design for the question it aimed to answer (i.e., whether the level of evidence is adequate). To do this, we need to know how to classify studies in function of their design (descriptive or analytical; prospective or retrospective; cross-sectional or longitudinal) as well as their correlation with the levels of evidence. In critical reading it is also important to know the main systematic errors or biases that can affect a study. Biases can appear in any phase of a study; they can affect the sample, the development of the study, or the measurement of the results.

  15. Study on categorization of the safety design evaluation event

    Energy Technology Data Exchange (ETDEWEB)

    Kurisaka, Kenichi; Kani, Yoshio [Power Reactor and Nuclear Fuel Development Corp., Oarai, Ibaraki (Japan). Oarai Engineering Center

    1997-05-01

    In order to make a FBR practicable, it is important to make rational categorization of a safety design evaluation event. In this study, for the purpose of providing useful information into the event categorization, we developed the occurrence frequency data of various abnormal events, presented a proposal of the event categorization primarily based on the occurrence frequency and examined efficiency of the proposal. We researched and analyzed abnormal event instances of foreign and domestic FBR plants and of domestic light water reactor power plants. On the basis of the analysis, the failure occurrence frequency of the protection system (PS) in the FBR model plants with electric power production of 600MW and 1,000MW was quantified. Making use of results of probabilistic safety assessment study, loss-of-function probability of the mitigation system (MS) was quantified. Some of combinations of PS failure and loss of MS function were selected and their occurrence frequencies were quantified. We examined problems in the current categorization of the safety design evaluation event and presented a new proposal of the event categorization. Merits of the new proposal are to have divided the current category of `accident` into `small accident` and `rare accident`, explicitly to treat a multiple failure event not as a collateral analysis condition of supposing `a single failure` but as an event to be evaluated, and to have added a category for the event which is beyond design base, but should be supposed to evaluate depth of the safety design in terms of defense-in-depth. Some candidates of the safety design evaluation event were identified and applied to the new proposal. In comparison with the current categorization, we obtained perspective that it was possible to evaluate the safety design more in detail and effectively, especially depth of the safety design such as backup reactor shutdown system, decay heat removal function in a natural circulation mode etc. (J.P.N.)

  16. Conceptual design study of the K-DEMO magnet system

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Keeman, E-mail: kkeeman@nfri.re.kr [National Fusion Research Institute, 169-148 Gwahak-ro, Daejeon 305-806 (Korea, Republic of); Oh, Sangjun; Park, Jong Sung; Lee, Chulhee; Im, Kihak; Kim, Hyung Chan; Lee, Gyung-Su [National Fusion Research Institute, 169-148 Gwahak-ro, Daejeon 305-806 (Korea, Republic of); Neilson, George; Brown, Thomas; Kessel, Charles; Titus, Peter; Zhai, Yuhu [Princeton Plasma Physics Laboratory, Princeton, NJ 08543 (United States)

    2015-10-15

    Highlights: • Perform a preliminary conceptual study for a steady-state Korean DEMO reactor. • Present a preliminary design of TF (toroidal field) magnet. • Present a preliminary design of CS (central solenoid) magnet. • Present a preliminary design of PF (toroidal field) magnet. - Abstract: As the ITER is being constructed, there is a growing anticipation for an earlier realization of fusion energy. A major design philosophy for the initiated conceptual design study for a steady-state Korean fusion demonstration reactor (K-DEMO) is engineering feasibility. A two-staged development plan is envisaged. K-DEMO is designed not only to demonstrate a net electricity generation and a self-sustained tritium cycle, but also to be used, in its initial stage, as a component test facility. Then, in its second stage, a major upgrade is carried out by replacing in-vessel components in order to show a net electricity generation on the order of 500 MWe. After a thorough 0-D system analysis, the major radius and minor radius are chosen to be 6.8 m and 2.1 m, respectively. In order to minimize wave deflection, a top-launch high frequency (>200 GHz) electron cyclotron current drive (ECCD) system will be the key system for the current profile control. For matching the high frequency ECCD, a high toroidal field (TF) is required and can be achieved by using high current density Nb{sub 3}Sn superconducting conductor. The peak magnetic field reaches to 16 T with the magnetic field at the plasma center above 7 T. Key features of the K-DEMO magnet system include the use of two TF coil winding packs, each of a different conductor design, to reduce the construction cost and save the space for the magnet structure material.

  17. The case-crossover study design in pharmacoepidemiology.

    Science.gov (United States)

    Delaney, Joseph A 'Chris'; Suissa, Samy

    2009-02-01

    In the study of the association of transient drug exposures with acute outcomes, the case-crossover design is an efficient alternative to the case-control approach. This design based exclusively on the case series uses within-subject comparisons of drug exposures over time to estimate the rate ratio of the outcome associated with the drug under study. This design inherently removes the biasing effects of unmeasured, time-invariant confounding factors from the estimated rate ratio, but is sensitive to several assumptions. We illustrated the case-crossover design and explored its sensitivity using data from 4028 cases of gastrointestinal bleeding from the General Practice Research Database in assessing the effects of the drug warfarin. We compared the use of different time window lengths to assess exposure and considered the use of a case-time-control design to account for exposure time trends. The case-crossover approach found no excess risk of bleeding with warfarin exposure [rate ratio 0.98; 95% confidence interval (CI): 0.74-1.28] using a 1-month time window. When we restricted the analysis to subjects with truly transient drug exposure, defined by 1 to 3 prescriptions in the previous year, the rate ratio was 2.59 (95% CI: 1.42-4.74). To consider the longer 1-year exposure time window, the case-time-control approach was used and resulted in a rate ratio of 1.72 (95% CI: 1.08-2.43). In conclusion, the case-crossover design is potentially a powerful approach to assess the risk of drugs. This design is, however, highly sensitive to assumptions about intermittency of drug use and the length of the exposure time window, as demonstrated with the example of bleeding associated with warfarin use.

  18. Utilization of Optimal Study Design for Maternal and Fetal Sheep Propofol Pharmacokinetics Study: A Preliminary Study

    Science.gov (United States)

    Sherwin, Catherine M. T.; Ngamprasertwong, Pornswan; Sadhasivam, Senthilkumar; Vinks, Alexander A.

    2017-01-01

    Multiple blood samples are generally required for measurement of pharmacokinetic (PK) parameters. D-optimal design is a popular and frequently used approach for determination of sampling time points in order to minimize the number of samples, while optimizing the estimation of PK parameters. Optimal design utilizing ADAPT (v5, BSR, University of Southern California, Los Angeles) developed a sparse sampling strategy to determine measurement of propofol in pregnant sheep. Propofal was administered as supplemental anesthetic agent to inhalation anesthesia to mimic anesthesia for open fetal surgery. In our preliminary study, propofol 3 mg/kg was given as a bolus to the ewe, followed by propofol infusion at rate 450 mcg/kg/min for 60 minutes, then decreased to 75 mcg/kg/min for 90 more minutes and then ceased. A three compartment model described the PK parameters with the fetus assumed as the third compartment. Initially, sampling times were chosen from thirteen time points as previously stated in the literature. Using priori propofol PK estimates, the final 9 sample time points were proposed in an optimal design with a change in infusion rate occurring between 65 and 75 minutes and sampling proposed at 5, 15, 25, 65, 75, 100, 110, 150, and 180 minutes. D-optimal design optimized the number and timing of samplings, which led to a reduction of cost and man power in the study protocol while preserving the ability to estimate propofol PK parameters in the maternal and fetal sheep model. Initial evaluation of samples collected from three sheep using the optimal design strategy confirmed the performance of the design in obtaining effective PK parameter estimates. PMID:24219004

  19. Design of an electromagnetic accelerator for turbulent hydrodynamic mix studies

    Energy Technology Data Exchange (ETDEWEB)

    Susoeff, A.R.; Hawke, R.S.; Morrison, J.J.; Dimonte, G.; Remington, B.A.

    1993-12-08

    An electromagnetic accelerator in the form of a linear electric motor (LEM) has been designed to achieve controlled acceleration profiles of a carriage containing hydrodynamically unstable fluids for the investigation of the development of turbulent mix. The Rayleigh- Taylor instability is investigated by accelerating two dissimilar density fluids using the LEM to achieve a wide variety of acceleration and deceleration profiles. The acceleration profiles are achieved by independent control of rail and augmentation currents. A variety of acceleration-time profiles are possible including: (1) constant, (2) impulsive and (3) shaped. The LEM and support structure are a robust design in order to withstand high loads with deflections and to mitigate operational vibration. Vibration of the carriage during acceleration could create artifacts in the data which would interfere with the intended study of the Rayleigh-Taylor instability. The design allows clear access for diagnostic techniques such as laser induced fluorescence radiography, shadowgraphs and particle imaging velocimetry. Electromagnetic modeling codes were used to optimize the rail and augmentation coil positions within the support structure framework. Results of contemporary studies for non-arcing sliding contact of solid armatures are used for the design of the driving armature and the dynamic electromagnetic braking system. A 0. 6MJ electrolytic capacitor bank is used for energy storage to drive the LEM. This report will discuss a LEM design which will accelerate masses of up to 3kg to a maximum of about 3000g{sub o}, where g{sub o} is accelerated due to gravity.

  20. Comparative study of codes for the seismic design of structures

    Directory of Open Access Journals (Sweden)

    S. H. C. Santos

    Full Text Available A general evaluation of some points of the South American seismic codes is presented herein, comparing them among themselves and with the American Standard ASCE/SEI 7/10 and with the European Standard Eurocode 8. The study is focused in design criteria for buildings. The Western border of South America is one of the most seismically active regions of the World. It corresponds to the confluence of the South American and Nazca plates. This region corresponds roughly to the vicinity of the Andes Mountains. This seismicity diminishes in the direction of the comparatively seismically quieter Eastern South American areas. The South American countries located in its Western Border possess standards for seismic design since some decades ago, being the Brazilian Standard for seismic design only recently published. This study is focused in some critical topics: definition of the recurrence periods for establishing the seismic input; definition of the seismic zonation and design ground motion values; definition of the shape of the design response spectra; consideration of soil amplification, soil liquefaction and soil-structure interaction; classification of the structures in different importance levels; definition of the seismic force-resisting systems and respective response modification coefficients; consideration of structural irregularities and definition of the allowable procedures for the seismic analyses. A simple building structure is analyzed considering the criteria of the several standards and obtained results are compared.

  1. On adaptive optimal input design: A bioreactor case study

    NARCIS (Netherlands)

    Stigter, J.D.; Vries, D.; Keesman, K.J.

    2006-01-01

    The problem of optimal input design (OID) for a fed-batch bioreactor case study is solved recursively. Here an adaptive receding horizon optimal control problem, involving the so-called E-criterion, is solved on-line, using the current estimate of the parameter vector at each sample instant {tk, k =

  2. Designing Intervention Studies: Selected Populations, Range Restrictions, and Statistical Power

    Science.gov (United States)

    Miciak, Jeremy; Taylor, W. Pat; Stuebing, Karla K.; Fletcher, Jack M.; Vaughn, Sharon

    2016-01-01

    An appropriate estimate of statistical power is critical for the design of intervention studies. Although the inclusion of a pretest covariate in the test of the primary outcome can increase statistical power, samples selected on the basis of pretest performance may demonstrate range restriction on the selection measure and other correlated…

  3. Usability Studies and User-Centered Design in Digital Libraries

    Science.gov (United States)

    Comeaux, David J.

    2008-01-01

    Digital libraries continue to flourish. At the same time, the principles of user-centered design and the practice of usability testing have been growing in popularity, spreading their influence into the library sphere. This article explores the confluence of these two trends by surveying the current literature on usability studies of digital…

  4. Usability Studies and User-Centered Design in Digital Libraries

    Science.gov (United States)

    Comeaux, David J.

    2008-01-01

    Digital libraries continue to flourish. At the same time, the principles of user-centered design and the practice of usability testing have been growing in popularity, spreading their influence into the library sphere. This article explores the confluence of these two trends by surveying the current literature on usability studies of digital…

  5. Factorial study of rain garden design for nitrogen removal

    Science.gov (United States)

    Abstract Nitrate (〖NO〗_3^--N ) removal studies in bioretention systems showed great variability in removal rates and in some cases 〖NO〗_3^--N was exported. A 3-way factorial design (2 x 2 x 4) was devised for eight outdoor un-vegetated rain gardens to evaluate the effects of ...

  6. The design and methodology of premature ejaculation interventional studies.

    Science.gov (United States)

    McMahon, Chris G

    2016-08-01

    Large well-designed clinical efficacy and safety randomized clinical trials (RCTs) are required to achieve regulatory approval of new drug treatments. The objective of this article is to make recommendations for the criteria for defining and selecting the clinical trial study population, design and efficacy outcomes measures which comprise ideal premature ejaculation (PE) interventional trial methodology. Data on clinical trial design, epidemiology, definitions, dimensions and psychological impact of PE was reviewed, critiqued and incorporated into a series of recommendations for standardisation of PE clinical trial design, outcome measures and reporting using the principles of evidence based medicine. Data from PE interventional studies are only reliable, interpretable and capable of being generalised to patients with PE, when study populations are defined by the International Society for Sexual Medicine (ISSM) multivariate definition of PE. PE intervention trials should employ a double-blind RCT methodology and include placebo control, active standard drug control, and/or dose comparison trials. Ejaculatory latency time (ELT) and subject/partner outcome measures of control, personal/partner/relationship distress and other study-specific outcome measures should be used as outcome measures. There is currently no published literature which identifies a clinically significant threshold response to intervention. The ISSM definition of PE reflects the contemporary understanding of PE and represents the state-of-the-art multi-dimensional definition of PE and is recommended as the basis of diagnosis of PE for all PE clinical trials.

  7. Business Studies within Design and Technology: Continuity and Progression.

    Science.gov (United States)

    Mathews, Maggie; Swainston, David

    1992-01-01

    Explores the placement of business studies courses within design and technology education programs in the United Kingdom. Reports the sense of isolation felt by business educators. Suggests a progression by which economic concepts could be taught on the various grade levels. Calls for further discussion of the proposal. (SG)

  8. Service-Learning and Interior Design: A Case Study

    Science.gov (United States)

    Sterling, Mary

    2007-01-01

    The case study approach was used to analyze experiential learning through its three components: knowledge, action, and reflection. Two interior design courses were integrated through a university service-learning project. The restoration/adaptive reuse of a 95-year-old library building was to serve as a prototype for future off-campus…

  9. Aeronautics Study Takes Off! Glider Design for Beginners

    Science.gov (United States)

    Lazaros, Edward J.; Carlson, Katie

    2008-01-01

    Study of aeronautics is an interesting and motivating subject for students and educators alike. The activity described in this article--appropriate for upper elementary or middle school students--provides an excellent introduction to airplane design and the science of aerodynamics. It also gives students good experience applying knowledge from a…

  10. Statistical approaches to the design of toxicology studies.

    Science.gov (United States)

    Gad, S C

    2001-01-01

    Application of statistics to toxicological studies involves hypothesis testing, model fitting, and reduction of dimensionality. This unit reviews statistical approaches to data (i.e., descriptive statistics, experimental design, outliers and rounding of numbers, and specific applications) and includes a set of decision trees to assist in choosing the appropriate methods.

  11. Service-Learning and Interior Design: A Case Study

    Science.gov (United States)

    Sterling, Mary

    2007-01-01

    The case study approach was used to analyze experiential learning through its three components: knowledge, action, and reflection. Two interior design courses were integrated through a university service-learning project. The restoration/adaptive reuse of a 95-year-old library building was to serve as a prototype for future off-campus…

  12. Study Design and Data Gathering Guide for Serious Games’ Evaluation

    NARCIS (Netherlands)

    Baalsrud Hauge, Jannicke; Boyle, Elizabeth; Mayer, Igor; Nadolski, Rob; Riedel, Johann C. K. H.; Moreno-Ger, Pablo; Bellotti, Francesco; Lim, Theodore; Ritchie, James

    2013-01-01

    Baalsrud Hauge, J., Boyle, E., Mayer, I., Nadolski, R. J., Riedel, J. C. K. H., Moreno-Ger, P., Bellotti, F., Lim, T., & Ritchie, J. (2013). Study Design and Data Gathering Guide for Serious Games’ Evaluation. In T. M. Connolly, T. Hainey, E. Boyle, G. Baxter, & P. Moreno-Ger (Eds.), Psychology,

  13. Conflicts Management Model in School: A Mixed Design Study

    Science.gov (United States)

    Dogan, Soner

    2016-01-01

    The object of this study is to evaluate the reasons for conflicts occurring in school according to perceptions and views of teachers and resolution strategies used for conflicts and to build a model based on the results obtained. In the research, explanatory design including quantitative and qualitative methods has been used. The quantitative part…

  14. Conceptual design study of a scyllac fusion test reactor

    Energy Technology Data Exchange (ETDEWEB)

    Thomassen, K.I. (comp.)

    1975-07-01

    The report describes a conceptual design study of a fusion test reactor based on the Scyllac toroidal theta-pinch approach to fusion. It is not the first attempt to describe the physics and technology required for demonstrating scientific feasibility of the approach, but it is the most complete design in the sense that the physics necessary to achieve the device goals is extrapolated from experimentally tested MHD theories of toroidal systems,and it uses technological systems whose engineering performance has been carefully calculated to ensure that they meet the machine requirements.

  15. A Structured Design for Test Methodology: A Case Study

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    This paper is a case study of a structured Design for Test (DFT) methodology that was adopted for our ASIC project used in High-Definition TV system. The methodology includes the following features, full-scan for chip test, test point insertion, test, path delay test, embedded SRAM Build-In Self Test (BIST), and also the implementation of IEEE 1149.1 Standard. The paper discusses details of the ASIC designs and technology. Our chip has a 2+ million transistors and large embedded memory, which brought us extra test challenge.

  16. Study and Design on Amphibious Ship for Sightseeing Amusement

    Directory of Open Access Journals (Sweden)

    Xiaowei Jiang

    2014-06-01

    Full Text Available The study purposes is to design a new tourism appliance that is beautifully shaped, easy to operate, in line with the ergonomics and could happily combine fitness and entertainment. It is an amphibious ship applicable to park or amusement park, which not only travels in water, but also on ground. This article specifically researches its working principle, internal structure and appearance shape, including the design of aquatic motion mechanism and ground motion mechanism. And then its market prospect is analyzed. On this basis, the corresponding conclusions are reached.

  17. Gene–Environment Interaction: Definitions and Study Designs

    OpenAIRE

    Ottman, Ruth

    1996-01-01

    Study of gene–environment interaction is important for improving accuracy and precision in the assessment of both genetic and environmental influences. This overview presents a simple definition of gene–environment interaction and suggests study designs for detecting it. Gene–environment interaction is defined as “a different effect of an environmental exposure on disease risk in persons with different genotypes,” or, alternatively, “a different effect of a genotype on disease risk in persons...

  18. Designing for Nomadic Play: A case study of participatory design with children

    DEFF Research Database (Denmark)

    Brynskov, Martin; Christensen, Bent Guldbjerg; Ludvigsen, Martin

    This poster presents the results from an empirical probe study trying to engage children creatively in the design process of systems and artifacts that support nomadic life-style. Based on observational studies and interviews with children of different ages (5-15 years), we conducted...... a participatory design workshop cycle where children were encouraged to envision and virtually play with not-yet-invented future technology. Findings include qualitative characterizations of children’s activities (e.g. ‘play’ culture, use of digital media, age and gender differences, relation to space......) and methodological considerations (e.g. the role of context and structure for different age groups, workshop formats, expenditure of time)....

  19. Kids in the city study: research design and methodology

    Directory of Open Access Journals (Sweden)

    Kaiwai Hector

    2011-07-01

    Full Text Available Abstract Background Physical activity is essential for optimal physical and psychological health but substantial declines in children's activity levels have occurred in New Zealand and internationally. Children's independent mobility (i.e., outdoor play and traveling to destinations unsupervised, an integral component of physical activity in childhood, has also declined radically in recent decades. Safety-conscious parenting practices, car reliance and auto-centric urban design have converged to produce children living increasingly sedentary lives. This research investigates how urban neighborhood environments can support or enable or restrict children's independent mobility, thereby influencing physical activity accumulation and participation in daily life. Methods/Design The study is located in six Auckland, New Zealand neighborhoods, diverse in terms of urban design attributes, particularly residential density. Participants comprise 160 children aged 9-11 years and their parents/caregivers. Objective measures (global positioning systems, accelerometers, geographical information systems, observational audits assessed children's independent mobility and physical activity, neighborhood infrastructure, and streetscape attributes. Parent and child neighborhood perceptions and experiences were assessed using qualitative research methods. Discussion This study is one of the first internationally to examine the association of specific urban design attributes with child independent mobility. Using robust, appropriate, and best practice objective measures, this study provides robust epidemiological information regarding the relationships between the built environment and health outcomes for this population.

  20. An Industrial Case Study: Identification of Competencies of Design Engineers

    DEFF Research Database (Denmark)

    Ahmed, Saeema

    2007-01-01

    identified and the importance of these for design engineers in industry was investigated. In addition, the number of years of relevant experience required to become an expert in these types of knowledge was investigated. Knowledge related to the process was perceived as more important to those related......This paper describes the findings from an empirical study carried out with engineers in senior roles within a large company manufacturing complex products. This research aimed to identify the types of knowledge that are important for design engineers. Twenty-four knowledge categories were...... to the product. However, the number of years to become an expert in process knowledge was found to be lower than for product knowledge, despite process knowledge being perceived as more important. The findings of this research contribute to the education and training of design engineers....

  1. ENERGY DEPOSITION STUDIES FOR POSSIBLE INNOVATIVE PHASE II COLLIMATOR DESIGNS

    CERN Document Server

    Lari, L; Brugger, M; Cerutti, F; Ferrari, A; Vlachoudis, V; Weiler, T

    2009-01-01

    Due to the known limitations of Phase I LHC collimators in stable physics conditions, the LHC collimation system will be complemented by additional 30 Phase II collimators. The Phase II collimation system is designed to improve cleaning efficiency and to minimize the collimator-induced impedance with the main function of protecting the Super Conducting (SC) magnets from quenching due to beam particle losses. To fulfil these requirements, different possible innovative collimation designs were taken in consideration. Advanced jaw materials, including new composite materials (e.g. Cu–Diamond), jaw SiC insertions, coating foil, in-jaw instrumentation (e.g. BPM) and improved mechanical robustness of the jaw are the main features of these new promising Phase II collimator designs developed at CERN. The FLUKA Monte Carlo code is extensively used to evaluate the behavior of these collimators in the most radioactive areas of LHC, supporting the mechanical integration. These studies aim to identify the possible criti...

  2. Energy Deposition Studies for Possible Innovative Phase II Collimator Designs

    CERN Document Server

    Lari, L; Brugger, M; Cerutti, F; Ferrari, A; Vlachoudis, V; Weiler, T

    2010-01-01

    Due to the known limitations of Phase I LHC collimators in stable physics conditions, the LHC collimation system will be complemented by additional 30 Phase II collimators. The Phase II collimation system is designed to improve cleaning efficiency and to minimize the collimator-induced impedance with the main function of protecting the Super Conducting (SC) magnets from quenching due to beam particle losses. To fulfil these requirements, different possible innovative collimation designs were taken in consideration. Advanced jaw materials, including new composite materials (e.g. Cu–Diamond), jaw SiC insertions, coating foil, in-jaw instrumentation (e.g. BPM) and improved mechanical robustness of the jaw are the main features of these new promising Phase II collimator designs developed at CERN. The FLUKA Monte Carlo code is extensively used to evaluate the behavior of these collimators in the most radioactive areas of LHC, supporting the mechanical integration. These studies aim to identify the possible criti...

  3. Design and experimental study of a novel giant magnetostrictive actuator

    Science.gov (United States)

    Xue, Guangming; Zhang, Peilin; He, Zhongbo; Li, Dongwei; Huang, Yingjie; Xie, Wenqiang

    2016-12-01

    Giant magnetostrictive actuator has been widely used in precise driving occasions for its excellent performance. However, in driving a switching valve, especially the ball-valve in an electronic controlled injector, the actuator can't exhibit its good performance for limits in output displacement and responding speed. A novel giant magnetostrictive actuator, which can reach its maximum displacement for being exerted with no bias magnetic field, is designed in this paper. Simultaneously, elongating of the giant magetostrictive material is converted to shortening of the actuator's axial dimension with the help of an output rod in "T" type. Furthermore, to save responding time, the driving voltage with high opening voltage while low holding voltage is designed. Responding time and output displacement are studied experimentally with the help of a measuring system. From measured results, designed driving voltage can improve the responding speed of actuator displacement quite effectively. And, giant magnetostrictive actuator can output various steady-state displacements to reach more driving effects.

  4. APPLIED KNOWLEDGE MANAGEMENT IN SMALL DESIGN FIRMS: CASE STUDY

    Directory of Open Access Journals (Sweden)

    Christian Donin

    2016-09-01

    Full Text Available Knowledge is the new strategic imperative of organizations. The ability to manage knowledge is a crucial part of any organizations operational processes. The creation and diffusion of knowledge have become ever more important factors in competitiveness. This paper investigates the Knowledge Management and flow information and in small design firms. It is divided into three main parts. The first part of this paper describes the importance of Knowledge Management for organizations are described together with responsibilities needed to ensure successful Knowledge Management implementations and the Spiral of Organizational Knowledge Creation conception. The second part approaches literature available about process and organizational structure and information flow related to Brazilian design firms. Finally, this paper presents a case study of small design office of Civil Engineering identifying organizational process, verifying the types of communication practices and identifying the types of dynamic process of The Spiral of Organizational Knowledge Creation, KM strategy and dynamic through Knowledge Transfer.

  5. Design Study of a Superconducting Gantry for Carbon Beam Therapy

    CERN Document Server

    Kim, J

    2016-01-01

    This paper describes the design study of a gantry for a carbon beam. The designed gantry is compact such that its size is comparable to the size of the proton gantry. This is possible by introducing superconducting double helical coils for dipole magnets. The gantry optics is designed in such a way that it provides rotation-invariant optics and variable beam size as well as point-to-parallel scanning of a beam. For large-aperture magnet, three-dimensional magnetic field distribution is obtained by invoking a computer code, and a number of particles are tracked by integrating equations of motion numerically together with three-dimensional interpolation. The beam-shape distortion due to the fringe field is reduced to an acceptable level by optimizing the coil windings with the help of genetic algorithm. Higher-order transfer coefficients are calculated and shown to be reduced greatly with appropriate optimization of the coil windings.

  6. A design study on the CSNS LEBT pre-chopper

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The China Spallation Neutron Source (CSNS) front end incorporates a pre-chopper in the Low Energy Beam Transport line (LEBT) that will remove a 530 ns section of beam at approximately 1 MHz rate, which is the RF frequency of the ring at injection. It’s one of the most critical devices for properly controlling the injecting beam loss. Physical designing of the pre-chopper is carried out, and the RFQ itself is used as the beam dump of the chopper system. In order to examine the reliability of the pre-chopper design, the beam study of a similar chopper system is successfully performed. The results of physical design and experiments are presented.

  7. Architecture and Design for Virtual Conferences: A Case Study

    Directory of Open Access Journals (Sweden)

    Andrew Sempere

    2011-07-01

    Full Text Available This paper presents a case study of the design issues facing a large multi-format virtual conference. The conference took place twice in two different years, each time using an avatar-based 3D world with spatialized audio including keynote, poster and social sessions. Between year 1 and 2, major adjustments were made to the architecture and design of the space, leading to improvement in the nature of interaction between the participants. While virtual meetings will likely never supplant the effectiveness of face-to-face meetings, this paper seeks to outline a few design principles learned from this experience, which can be applied generally to make computer mediated collaboration more effective.

  8. Designing regional pattern for ecosystem restoration: A case study

    Institute of Scientific and Technical Information of China (English)

    LI Guoqiang; MA Keming; FU Bojie; LIU Shiling

    2006-01-01

    Designing regional pattern is challenging for ecosystem restoration both in theory and in practice. The present study proposed a new approach to design regional pattern for ecosystem restoration with a case in the arid valley of Upper Minjiang River, SW China. The procedures are: (1) Determine the regional pattern of main environmental factors based on the relationships between the important environmental factors and the main geographical factors generated from DEM data. (2) Overlay the maps of the main environmental factors. (3) Generate a lookup table according to the species selection rule we proposed to link the candidate restoration species to the main environmental factors.(4) Determine the regional pattern of ecosystem restoration by positioning the restoration species in the map of environmental factors according to the lookup table. The regional restoration pattern designed in this way would be applicable not only to restoring a region, but also to predicting the future landscape change.

  9. Design of Laboratory Experiments to Study Photoionization Fronts

    Science.gov (United States)

    Gray, William James; Davis, Josh; Drake, R. Paul

    2017-06-01

    Here we present the theoretical foundation for a laboratory experiment to study photoionization fronts. Photoionization fronts play important roles in the formation and evolution of structure in the Universe. A properly designed experiment will have to control the recombination rate, electron impact ionization rate, and the initial thermal spectrum. We show that such an experiment can be designed, but requires the use of the largest high-energy-density laser facilities, such as Omega, Z, and NIF. We also show that prior experiments do not actually generate photoionization fronts, rather a heat front is produced by heat conductions. We show some initial simulation results of the current experimental design and characterize the ionization front.

  10. Fuel lignocellulosic briquettes, die design and products study

    Energy Technology Data Exchange (ETDEWEB)

    Granada, E.; Miguez, J.L.; Moran, J. [Vigo Univ. (Spain). E.T.S. Ingenieros Industriales y Minas; Lopez Gonzalez, L.M. [Universidad de La Rioja (Spain). Departamento de Ingenieria Mecanica

    2002-12-01

    Briquetting of biomass can be done through various techniques. The present work describes the process of designing a taper die and its optimisation for use in a hydraulic machine. The application of an experimental design technique, and the later statistical analysis of the results is presented, applied to a laboratory hydraulic press densification process of lignocellulosic biomass. The most appropriate experiment type is determined for a first set of experiments; calculating, among other things: minimum number of tests to carry out to obtain binding conclusions, most influential factors, and search paths to improve fuel quality. Another experiment type is determined for a second set of experiments, taking account of the most influential factors (pressure, temperature and moisture content), and also the number of tests to carry out considering the improvement of density and friability. Finally, an approximation study of the best product allows conclusions to be reached on product behaviour beyond the experimental design range factors. (Author)

  11. Design studies of continuously variable transmissions for electric vehicles

    Science.gov (United States)

    Parker, R. J.; Loewenthal, S. H.; Fischer, G. K.

    1981-01-01

    Preliminary design studies were performed on four continuously variable transmission (CVT) concepts for use with a flywheel equipped electric vehicle of 1700 kg gross weight. Requirements of the CVT's were a maximum torque of 450 N-m (330 lb-ft), a maximum output power of 75 kW (100 hp), and a flywheel speed range of 28,000 to 14,000 rpm. Efficiency, size, weight, cost, reliability, maintainability, and controls were evaluated for each of the four concepts which included a steel V-belt type, a flat rubber belt type, a toroidal traction type, and a cone roller traction type. All CVT's exhibited relatively high calculated efficiencies (68 percent to 97 percent) over a broad range of vehicle operating conditions. Estimated weight and size of these transmissions were comparable to or less than equivalent automatic transmission. The design of each concept was carried through the design layout stage.

  12. The household contact study design for genetic epidemiological studies of infectious diseases

    Directory of Open Access Journals (Sweden)

    Catherine eStein

    2013-04-01

    Full Text Available Most genetic epidemiological study designs fall into one of two categories: family-based and population-based (case-control. However, recent advances in statistical genetics call for study designs that combine these two approaches. We describe the household contact study design as we have applied it in our several years of study of the epidemiology of tuberculosis. Though we highlight its applicability for genetic epidemiological studies of infectious diseases, there are many facets of this design that are appealing for modern genetic studies, including the simultaneous enrollment of related and unrelated individuals, closely and distantly related individuals, collection of extensive epidemiologic and phenotypic data, and evaluation of effects of shared environment and gene by environment interaction. These study design characteristics are particularly appealing for current sequencing studies.

  13. LUTE primary mirror materials and design study report

    Science.gov (United States)

    Ruthven, Greg

    1993-02-01

    The major objective of the Lunar Ultraviolet Telescope Experiment (LUTE) Primary Mirror Materials and Design Study is to investigate the feasibility of the LUTE telescope primary mirror. A systematic approach to accomplish this key goal was taken by first understanding the optical, thermal, and structural requirements and then deriving the critical primary mirror-level requirements for ground testing, launch, and lunar operations. After summarizing the results in those requirements which drove the selection of material and the design for the primary mirror are discussed. Most important of these are the optical design which was assumed to be the MSFC baseline (i.e. 3 mirror optical system), telescope wavefront error (WFE) allocations, the telescope weight budget, and the LUTE operational temperature ranges. Mechanical load levels, reflectance and microroughness issues, and options for the LUTE metering structure were discussed and an outline for the LUTE telescope sub-system design specification was initiated. The primary mirror analysis and results are presented. The six material substrate candidates are discussed and four distinct mirror geometries which are considered are shown. With these materials and configurations together with varying the location of the mirror support points, a total of 42 possible primary mirror designs resulted. The polishability of each substrate candidate was investigated and a usage history of 0.5 meter and larger precision cryogenic mirrors (the operational low end LUTE temperature of 60 K is the reason we feel a survey of cryogenic mirrors is appropriate) that were flown or tested are presented.

  14. A Detailed Study of Cbr Method for Flexible Pavement Design

    Directory of Open Access Journals (Sweden)

    Er. Devendra Kumar Choudhary

    2014-06-01

    Full Text Available As per IRC recommendation, California Bearing Ratio (CBR value of subgrade is used for design of flexible pavements. California Bearing Ratio (CBR value is an important soil parameter for design of flexible pavements and runway of air fields. It can also be used for determination of sub grade reaction of soil by using correlation. It is one of the most important engineering properties of soil for design of sub grade of roads. CBR value of soil may depends on many factors like maximum dry density (MDD, optimum moisture content (OMC, liquid limit (LL, plastic limit (PL, plasticity index (PI, type of soil, permeability of soil etc. Besides, soaked or unsoaked condition of soil also affects the value. These tests can easily be performed in the laboratory. the estimation of the CBR could be done on the basis of these tests which are quick to perform, less time consuming and cheap, then it will be easy to get the information about the strength of subgrade over the length of roads, By considering this aspect, a number of investigators in the past made their investigations in this field and designed different pavements by determining the CBR value on the basis of results of low cost, less time consuming and easy to perform tests. In this study, attempts have been made to seek the values of CBR of different soil samples and correlate their CBR values for the design purpose of flexible pavement as per guidelines of IRC: SP: 37-2001.

  15. Conceptual Design Study of 13 MeV Proton Cyclotron

    Directory of Open Access Journals (Sweden)

    Silakhuddin

    2012-04-01

    Full Text Available A study to determine the conceptual design of a 13 MeV proton cyclotron for PET (Positron Emission Tomography facility has been carried out. Based on studies on reactions of PET radioisotopes production, reaction cross-sections and some design references, a design of the proton cyclotron is proposed. The design criteria for the main components are decided using empirical and semitheoretical methods, as well as by referring to data regarding cyclotrons for PET production. The empirical method was carried out by using some data from operational experiences of BATAN cyclotron at Serpong, while the semitheoretical method was carried out by using the commonly used equations of cyclotron basic theory. The general layout of components and the main components, namely the ion source, the RF dees, the magnet, and the extractor are discussed. Based on the calculations and on the data used, the cyclotron is designed as a negative ion acceleration cyclotron with internal ion source. The designated proton energy and beam currents are 13 MeV and 50 µA. Its magnetic field is in the relativistic mode with sectors on the pole. The magnetic field intensity at the extraction radius is 12.745 kG and in the innermost radius is 12.571 kG. The magnetic poles consist of four sectors to make adequate space for components placement such as dees, ion source, extractor and beam probe. The dee angle is 430. The dee operates at 78 MHz on the fourth harmonic. A multifoil extractor is chosen to obtain an efficient operation

  16. Mixed methods research design for pragmatic psychoanalytic studies.

    Science.gov (United States)

    Tillman, Jane G; Clemence, A Jill; Stevens, Jennifer L

    2011-10-01

    Calls for more rigorous psychoanalytic studies have increased over the past decade. The field has been divided by those who assert that psychoanalysis is properly a hermeneutic endeavor and those who see it as a science. A comparable debate is found in research methodology, where qualitative and quantitative methods have often been seen as occupying orthogonal positions. Recently, Mixed Methods Research (MMR) has emerged as a viable "third community" of research, pursuing a pragmatic approach to research endeavors through integrating qualitative and quantitative procedures in a single study design. Mixed Methods Research designs and the terminology associated with this emerging approach are explained, after which the methodology is explored as a potential integrative approach to a psychoanalytic human science. Both qualitative and quantitative research methods are reviewed, as well as how they may be used in Mixed Methods Research to study complex human phenomena.

  17. Statistical Design Features of the Healthy Communities Study.

    Science.gov (United States)

    Strauss, Warren J; Sroka, Christopher J; Frongillo, Edward A; Arteaga, S Sonia; Loria, Catherine M; Leifer, Eric S; Wu, Colin O; Patrick, Heather; Fishbein, Howard A; John, Lisa V

    2015-10-01

    The Healthy Communities Study is designed to assess relationships between characteristics of community programs and policies targeting childhood obesity and children's BMI, diet, and physical activity. The study involved a complex data collection protocol implemented over a 2-year period (2013-2015) across a diverse sample of 130 communities, defined as public high school catchment areas. The protocol involved baseline assessment within each community that included in-person or telephone interviews regarding community programs and policies and in-home collection of BMI, nutritional, and physical activity outcomes from a sample of up to 81 children enrolled in kindergarten through eighth grade in public schools. The protocol also involved medical record reviews to establish a longitudinal trajectory of BMI for an estimated 70% of participating children. Staged sampling was used to collect less detailed measures of physical activity and nutrition across the entire sample of children, with a subset assessed using more costly, burdensome, and detailed measures. Data from the Healthy Community Study will be analyzed using both cross-sectional and longitudinal models that account for the complex design and correct for measurement error and bias using a likelihood-based Markov-chain Monte Carlo methodology. This methods paper provides insights into the complex design features of the Healthy Communities Study and may serve as an example for future large-scale studies that assess the relationship between community-based programs and policies and health outcomes of community residents.

  18. 体验式培训在社区舒缓疗护护士上岗前的实践与效果%Practice and effect of the experiential-based pre-post training about palliative treatment and care for the community nurses

    Institute of Scientific and Technical Information of China (English)

    刘颖颜; 明星; 杨敏; 朱波琴; 蒋申贞; 李宁; 江长缨; 梅久红

    2016-01-01

    目的:探讨社区舒缓疗护护士上岗前实施体验式培训的效果。方法:采用目的抽样方法选择40名社区舒缓疗护护士,运用情景模拟、案例分享、总结体会、实践应用等理论与临床实践相结合的体验式培训,并使用自行设计的社区护士舒缓疗护知识调查问卷、人际反应指针问卷(IRI-C)分别于培训前、后对护士进行测评。结果:护士的舒缓疗护知识总分高于培训前,差异有统计学意义(P<0.01),其中舒缓疗护概述、心理护理、灵性关怀知识得分高于培训前;人际反应总分培训前、后差异有统计学意义(P<0.05)。其中,幻想力、身心忧急得分均高于培训前(P<0.05)。结论:体验式培训是提高社区护士舒缓疗护知识与技能、共情能力的有效培训方法。%Objective:To explore the effect of the experiential-based pre-post training about palliative treatment and care for thecommunity nurses.Methods: With the purposive sampling method, 40 community palliative nurses were chosen and given the experience-based training combined with theory and clinical practice such as the application of scenario simulation, case sharing, summing up experience and practical application. The self designed questionnaire of community nurses’ knowledge about palliative care and the interpersonal reactivity index questionnaire were used to evaluate the effects of the training for nurses before and after the training, respectively.Results: The total score of hospice care knowledge of the nurses was higher after training than that before training(P<0.01), among which the scores of an overview of the palliative care knowledge, psychological care and spiritual care knowledge were higher after training than those before training. The difference in the interpersonal reactivity index had the statistical signiifcance before and after training(P<0.05), among which the scores of fancy and physical and

  19. An Exploratory Study to Investigate the Impact of an Enrichment Program on Aspects of Einsteinian Physics on Year 6 Students

    Science.gov (United States)

    Pitts, Marina; Venville, Grady; Blair, David; Zadnik, Marjan

    2014-06-01

    Concepts related to Einsteinian physics are usually not taught until students are in university, denying younger children access to this powerful way of understanding space, time and gravity. Considerable research has shown, however, that complex and abstract scientific ideas can be presented in age appropriate ways that result in measurable learning. The purpose of the research presented in this paper was to explore the impact of an enrichment program on aspects of Einsteinian physics on year 6 (10 and 11 years old) children's understanding of and attitudes towards this topic. The research design was an exploratory case study of one class of 26 students who participated in six in-class lessons as well as an excursion to a science centre, the Gravity Discovery Centre, and a scripted play about relevant key scientists. Mixed methods of data collection included a pre/post-instruction questionnaire, classroom observations and an interview with the physics professor who conducted the program. The results indicated a statistically significant improvement in children's conceptual understanding on the pre/post-questionnaire with a small effect size. Analysis of individual items on the questionnaire indicated variable results with regard to particular concepts. For example, after the enrichment program, students were better able to understand curved space, but little improvement was observed in their understanding of gravity on the Moon. The majority of students reported being interested and engaged in the program of activities and did not feel that they were too young to learn concepts related to Einstein's physics.

  20. New design studies for TRIUMF's ARIEL High Resolution Separator

    Science.gov (United States)

    Maloney, J. A.; Baartman, R.; Marchetto, M.

    2016-06-01

    As part of its new Advanced Rare IsotopE Laboratory (ARIEL), TRIUMF is designing a novel High Resolution Separator (HRS) (Maloney et al., 2015) to separate rare isotopes. The HRS has a 180° bend, separated into two 90° magnetic dipoles, bend radius 1.2 m, with an electrostatic multipole corrector between them. Second order correction comes mainly from the dipole edge curvatures, but is intended to be fine-tuned with a sextupole component and a small octupole component in the multipole. This combination is designed to achieve 1:20,000 resolution for a 3 μm (horizontal) and 6 μm (vertical) emittance. A design for the HRS dipole magnets achieves both radial and integral flatness goals of <10-5. A review of the optical design for the HRS is presented, including the study of limiting factors affecting separation, matching and aberration correction. Field simulations from the OPERA-3D (OPERA) [2] models of the dipole magnets are used in COSY Infinity (COSY) (Berz and Makino, 2005) [3] to find and optimize the transfer maps to 3rd order and study residual nonlinearities to 8th order.

  1. A Study on the Design of Electronic SAMG Functional Modules

    Energy Technology Data Exchange (ETDEWEB)

    Park, S. H.; Kim, J. H.; Ahn, K. I. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-10-15

    This paper describes a study on the design of e-SAMG functional modules. A study of for the design of e-SAMG was introduced. During an emergency status of a severe accident, the items for the functional module during a rapid and exact action are surveyed. The results are being implemented in e-SAMG. The operators can be supported through the use of e-SAMG. Based on the design of functional modules, the implementation will be accelerated and the refined design can also be applied. As a part of the Ministry of Science, ICT and future Planning (MSIP) Project, we at KAERI are developing electronic SAMG (e-SAMG, severe accident mitigation guideline) for general SAMG for nuclear power plants. Due to computerized trends, various efforts related to computer systems have been carried out for safety systems in nuclear power plants. In particular, since the Fukushima accident, unexpected accidents or extreme damages have become a concern. With this status, a rapid and exact confrontation such as a computerized attempt in SAMG has been tried. To develop an electronic SAMG, based on an analysis of the general SAMG, the architecture of e-SAMG was founded. The functional modules occupy important parts in the e-SAMG.

  2. Outline and Status of the FCC-ee Design Study

    CERN Document Server

    Zimmermann, Frank

    2015-01-01

    The Update of the European Strategy for Particle Physics in 2013 [1] declared as its second highest priority that “…to propose an ambitious post-LHC accelerator project….., CERN should undertake design studies for accelerator projects in a global context,…with emphasis on proton-proton and electron-positron high-energy frontier machines…”. In response to this request, the global Future Circular Collider (FCC) study is designing a 100-TeV proton collider (FCC-hh) in a new ~100 km tunnel near Geneva, a high-luminosity electron-positron collider (FCC-ee) as a potential intermediate step, and a lepton-hadron option (FCC-he). The FCC study comprises accelerators, technology, infrastructure, detector, physics, concepts for worldwide data services, international governance models, and implementation scenarios. The FCC study is mandated to deliver a Conceptual Design Report and preliminary cost estimate by the time of the next European Strategy Update expected for 2019. As of July 2015, 58 institutes from...

  3. Bridging Translation by Improving Preclinical Study Design in AKI.

    Science.gov (United States)

    de Caestecker, Mark; Humphreys, Ben D; Liu, Kathleen D; Fissell, William H; Cerda, Jorge; Nolin, Thomas D; Askenazi, David; Mour, Girish; Harrell, Frank E; Pullen, Nick; Okusa, Mark D; Faubel, Sarah

    2015-12-01

    Despite extensive research, no therapeutic interventions have been shown to prevent AKI, accelerate recovery of AKI, or reduce progression of AKI to CKD in patients. This failure in translation has led investigators to speculate that the animal models being used do not predict therapeutic responses in humans. Although this issue continues to be debated, an important concern that has not been addressed is whether improvements in preclinical study design can be identified that might also increase the likelihood of translating basic AKI research into clinical practice using the current models. In this review, we have taken an evidence-based approach to identify common weaknesses in study design and reporting in preclinical AKI research that may contribute to the poor translatability of the findings. We focused on use of N-acetylcysteine or sodium bicarbonate for the prevention of contrast-induced AKI and use of erythropoietin for the prevention of AKI, two therapeutic approaches that have been extensively studied in clinical trials. On the basis of our findings, we identified five areas for improvement in preclinical study design and reporting. These suggested and preliminary guidelines may help improve the quality of preclinical research for AKI drug development.

  4. Design Improvement Study for Passive Shutdown System of the PGSFR

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jae-Han; Koo, Gyeong-Ho [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-10-15

    There have been no experiences of implementing a passive shutdown system in operating or operated SFRs around the world. However, new SFRs are considered to adopt a self-actuated shutdown system (SASS) in the future to provide an alternate means of passively shutting down the reactor. The Prototype Gen-IV SFR (PGSFR) also adopts this system for the same reason. This passive shutdown design concept is combined with a group of secondary control rod drive mechanisms (SCRDM). The system automatically releases the control rod assembly (CRA) around the set temperature, and then drops the CRA by gravity without any external control signals and any actuating power in an emergency of the reactor. This paper describes the design upgrade parametric study of a passive shutdown system, which consists of a thermal expansion device, an electromagnet, a secondary control rod assembly head, etc. The conceptual design values of each component are also suggested. Parametric calculations are performed to meet the performance requirements of the thermal expansion device and electromagnets. The maximum thermal expansion difference length of 3.6 mm is less than the target value of 5 mm, and the calculated electromagnet forces on the CRA are smaller than the target value of 800 N. An additional design improvement to increase the thermal expansion difference length of a thermal expansion device are necessary to meet the target value, and the electromagnetic force should be increased by an adjustment of the electromagnet design values such as supplied current, material permeability, etc. The design feasibility of the thermal expansion device as a passive concept will be verified based on these results.

  5. Design studies for the electron storage ring EUTERPE

    Energy Technology Data Exchange (ETDEWEB)

    Xi Boling

    1995-05-18

    The 400 MeV electron storage ring EUTERPE is under construction at Eindhoven University of Technology. The ring is to be used as an experimental tool for accelerator physics studies and synchroton radiation applications. The main task of the current research work is the electron optical design of the ring. Lattice design is a basis for machine design as a whole. Design aspects regarding the basic lattice, based on single particle dynamics, include determination of the equilibrium beam size and bunch length, design of achromatic bending sections, selection of tune values, correction of chromaticity, and minimization of the natural emittance in the ring. The basic lattice designed for the EUTERPE ring has a high flexibility so that different electron optical modes can be realized easily. In low energy storage rings with a high beam current, collective effects can cause a significant change in the bunch length, the transverse emittance and the beam lifetime. In order to ensure a good optical performance for the ring, the choice of suitable parameters concerning the vacuum and RF system are essential as far as collective effects are concerned. An estimation of the collective effects in the ring is given. The injector for EUTERPE is a 75 MeV racetrack microtron which is injected from a 10 MeV linac. In order to get sufficient beam current in the ring, a special procedure of continuous injection with an adjustable locally shifted closed orbit has been presented. Details of the injection procedure and numerical simulations are given. (orig./HSI).

  6. Summary of the Preliminary Optical ICHMI Design Study: A Preliminary Engineering Design Study for a Standpipe Viewport

    Energy Technology Data Exchange (ETDEWEB)

    Anheier, Norman C.; Qiao, Hong (Amy); Berglin, Eric J.; Hatchell, Brian K.

    2013-12-26

    This summary report examines an in-vessel optical access concept intended to support standoff optical instrumentation, control and human-machine interface (ICHMI) systems for future advanced small modular reactor (AdvSMR) applications. Optical-based measurement and sensing systems for AdvSMR applications have several key benefits over traditional instrumentation and control systems used to monitor reactor process parameters, such as temperature, flow rate, pressure, and coolant chemistry (Anheier et al. 2013). Direct and continuous visualization of the in-vessel components can be maintained using external cameras. Many optical sensing techniques can be performed remotely using open optical beam path configurations. Not only are in-vessel cables eliminated by these configurations, but also sensitive optical monitoring components (e.g., electronics, lasers, detectors, and cameras) can be placed outside the reactor vessel in the instrument vault, containment building, or other locations where temperatures and radiation levels are much lower. However, the extreme AdvSMR environment present challenges for optical access designs and optical materials. Optical access is not provided in any commercial nuclear power plant or featured in any reactor design, although successful implementation of optical access has been demonstrated in test reactors (Arkani and Gharib 2009). This report outlines the key engineering considerations for an AdvSMR optical access concept. Strict American Society of Mechanical Engineers (ASME) construction codes must be followed for any U.S. nuclear facility component (ASME 2013); however, the scope of this study is to evaluate the preliminary engineering issues for this concept, rather than developing a nuclear-qualified design. In addition, this study does not consider accident design requirements. In-vessel optical access using a standpipe viewport concept serves as a test case to explore the engineering challenges and performance requirements

  7. Studies and Design of the ECAL (CMS) Cooling System

    CERN Document Server

    Gasser, D

    2000-01-01

    The Electromagnetic CALorimeter (ECAL) sub-detector for the CMS experiment has to achieve very tight requirements in terms of temperature stability. The CV group is now involved in the design of a cooling system for ECAL. The status and the content of the work which has been done will be explained. The theoretical studies which helped to understand the ECAL thermal behaviour and the efficiency of the hydraulic network in charge of the cooling will first be briefly presented. Moreover, it will be shown how these studies helped to improve the cooling design inside ECAL. A proposal for an external cooling system of ECAL will be presented as well. Finally, experimental thermal tests, which are planned for April 2000 on a prototype corresponding to a part of ECAL, will be described. These tests aim to check the technical solutions which can be applied in the context of the real ECAL detector.

  8. Parametric design study of ``power stick'' and its derivatives

    Science.gov (United States)

    Schock, Alfred; Or, Chuen T.

    1995-01-01

    The paper addresses some major concerns about the Power Stick concept proposed by Jet Propulsion Laboratory (JPL) personnel, and describes parametric studies of derivative designs to determine to what extent those concerns can be alleviated. The Power Stick and its derivatives are based on the use of the 1-watt(t) Radioisotope Heater Unit (RHU) to power a thermoelectric multicouple. Our study concludes that: (a) while the RHU has been safety-qualified as a low-temperature heater, additional reentry analyses and test would be needed to qualify it as a higher temperature heat source for the Power Stick, (b) even after parametric design optimization, the efficiency of the Power Stick and its derivatives is only 2.2%, and, (c) all generators based on the 1-watt heat source require a thermoelectric multicouple with a large number of extremely thin legs, of very doubtful fabricability.

  9. Design dimensions: In-depth retrospective studies of K-12 science curriculum design

    NARCIS (Netherlands)

    Bernstein, Deborah; McKenney, Susan; Barber, Jacquey; Bopardikar, Anushree; Drayton, Brian; Walkup, Sara; Pareja Roblin, Natalie; Schunn, Christian

    2015-01-01

    Design and development are critically important to the educational enterprise. Unfortunately, there is little research on which design and development processes produce optimal outcomes for curricular materials intended for large-scale implementation. The Design Dimensions project asks: Across

  10. A Case Study of Introducing Innovation Through Design

    Science.gov (United States)

    2014-03-01

    TYPE AND DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE A CASE STUDY OF INTRODUCING INNOVATION THROUGH DESIGN 5. FUNDING NUMBERS 6...Jamming and Hanging Out paradigm outlined by Frank Barrett in his book Yes to the Mess: Surprising Leadership Lessons from Jazz .129 In these informal...jam sessions, jazz musicians are able to discover as a team—where they learn the common groove that will bring people together so they can learn

  11. Gradient-index ophthalmic lens design and polymer material studies

    Science.gov (United States)

    Fischer, David Joel

    Unifocal ophthalmic lenses are conventionally designed using homogeneous glass or plastic materials and aspheric surfaces. The desired power and aberration correction are provided by selection of surface shape and refractive index. This thesis studies the design of ophthalmic lenses utilizing gradient-index (GRIN) materials for both the optical power and aberration control. This is done using geometrical optical theory and ray-tracing simulations. Progressive addition lenses (PALS) are vision correction lenses with a continuous change in power used to treat presbyopia. The power variation is typically located in the lower half of the lens. Progressive addition lenses are currently made with aspheric surfaces to achieve the focal power transition and aberration control. These surfaces have at most, mirror symmetry about the vertical axis. The possible design of progressive addition lenses with GRIN materials has not been well studied. This thesis studies PALS and identifies how gradient-index materials can be used to provide both the power progression and aberration control. The optical theory for rotationally symmetric and asymmetric power additions is given. Analytical and numerical methods for calculating the index profile are used, and the results examined using ray-tracing simulations. The theory developed for ophthalmic lenses is applied to the design of GRIN axicon. This is the first GRIN axicon manufactured, and is fabricated using ion-exchanged GRIN glass. Experimental measurements of its performance are compared and found to match theoretical predictions. This demonstrates the generality of the theory developed: it may be applied to non-visual applications, and even to non-imaging applications. Realistic implementation of GRIN technology to ophthalmic application requires the fabrication of large scale refractive index gradients in polymer material systems. The methyl-methacrylate/styrene copolymer system is studied to develop an empirical model of its

  12. A Study on Task-based Language Teaching Syllabus Design

    Institute of Scientific and Technical Information of China (English)

    王振庆

    2013-01-01

      Task-based teaching syllabus becomes more and more popular in modern English teaching. It is widely used in the Eng⁃lish teaching from junior to senior high school and even to collage and university education. This paper is mainly studies the rele⁃vant research on task-based teaching syllabus and offers some tips on task-based syllabus design.

  13. Design study of ITER-like divertor target for DEMO

    Energy Technology Data Exchange (ETDEWEB)

    Crescenzi, Fabio, E-mail: fabio.crescenzi@enea.it [ENEA, Unità Tecnica Fusione, ENEA C. R. Frascati, via E. Fermi 45, 00044 Frascati (Roma) (Italy); Bachmann, C. [EFDA, Power Plant Physics and Technology, Boltzmannstraße 2, 85748 Garching (Germany); Richou, M. [CEA, IRFM, F-13108 Saint Paul Lez Durance (France); Roccella, S.; Visca, E. [ENEA, Unità Tecnica Fusione, ENEA C. R. Frascati, via E. Fermi 45, 00044 Frascati (Roma) (Italy); You, J.-H. [Max-Planck-Institut für Plasmaphysik, Boltzmannstr. 2, 85748 Garching (Germany)

    2015-10-15

    Highlights: • ‘DEMO’ is a near-term Power Plant Conceptual Study (PPCS). • The ITER-like design concept represents a promising solution also for DEMO plasma facing units. • The optimization of PFUs aims to enhance the thermo-mechanical behaviour of the component. • The optimized geometry was evaluated by ITER SDC-IC criteria and in terms of low cycle fatigue (LCF). - Abstract: A near-term water-cooled target solution has to be evaluated together with the required technologies and its power exhaust limit under ‘DEMO’ conditions. The ITER-like design concept based on the mono-block technology using W as armour material and the CuCrZr-IG as structural material with an interlayer of pure copper represents a promising solution also for DEMO. This work reports the design study of an “optimized” ITER-like Water Cooled Divertor able to withstand a heat flux of 10 MW m{sup −2}, as requested for DEMO operating conditions. The optimization of plasma facing unit (PFU) aims to enhance the thermo-mechanical behaviour of the component by varying some geometrical parameters (monoblock size, interlayer thickness and, tube diameter and thickness). The optimization was performed by means of the multi-variable optimization algorithms using the FEM code ANSYS. The coolant hydraulic conditions (inlet pressure, temperature and velocity) were fixed for simplicity. This study is based on elastic analysis and 3 dimensional modelling. The resulting optimized geometry was evaluated on the basis of the ITER SDC-IC criteria and in terms of low cycle fatigue (LCF). The margin to the critical heat flux (CHF) was also estimated. Further design study (taking into account the effect of neutron radiation on the material properties) together with mock-up fabrication and high-heat-flux (HHF) tests are foreseen in next work programmes.

  14. An overview of the HIE-ISOLDE Design Study

    Energy Technology Data Exchange (ETDEWEB)

    Catherall, R., E-mail: richard.catherall@cern.ch [CERN, CH-1211 Geneva 23 (Switzerland); Augustin, M.; Babcock, C.; Barlow, R.; Bernardes, A.P.; Cimmino, S.; Czapski, M.; Fowler, T.; Giles, T.; Hermann, M. [CERN, CH-1211 Geneva 23 (Switzerland); Huyse, M. [Instituut voor Kern-en Stralingsfysica, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Kadi, Y.; Marzari, S.; Montano, J.; Perillo Marcone, A.; Polato, A.; Stora, T.; Shornikov, A.; Vandoni, G. [CERN, CH-1211 Geneva 23 (Switzerland); Van Duppen, P. [Instituut voor Kern-en Stralingsfysica, Celestijnenlaan 200D, B-3001 Leuven (Belgium); and others

    2013-12-15

    Highlights: • Design Study within the HIE-ISOLDE project. • Issues associated with an increase in energy and intensity of primary proton beam. • Secondary ion beam quality improvements. -- Abstract: The On-Line Isotope Mass Separator ISOLDE [1] is a facility dedicated to the production of a large variety of radioactive ion beams (RIB) for a great number of different experiments. Over 1000 radioactive nuclides from 70 elements can be produced in thick high-temperature targets via spallation, fission or fragmentation reactions with the PS-Booster pulsed proton-beam. With the arrival of CERN’s new linear accelerator Linac 4 [2,3], ISOLDE will have the possibility to exploit a factor of 3 increase in proton-beam intensity and a possible proton-beam energy increase from 1.4 GeV to 2 GeV [4]. After 20 years of successful ISOLDE operation at the PS-Booster, a major upgrade of the facility, the HIE-ISOLDE (High Intensity and Energy ISOLDE) project was launched in 2010. It is divided into three parts; a staged upgrade of the REX post-accelerator to increase the beam energy from 3.3 MeV/u to 10 MeV/u using a super-conducting Linac, an evaluation of the critical issues associated with an increase in proton-beam intensity and a machine design for an improvement in RIB quality. The latter two will be addressed within the HIE-ISOLDE Design Study. This paper gives an overview of the Design Study and will outline the critical issues to be addressed concerning the intensity upgrade and will propose solutions and improvements to be implemented. It will also give an insight to the propositions being studied in order to improve secondary beam characteristics essential to accomplish a more demanding physics program.

  15. Research in dentistry: Question, search and studies design.

    OpenAIRE

    Pedro Aravena

    2012-01-01

    Evidence-based dentistry (EBD) concept has caused great impact and interest in the field of dentistry. For its development is important to use research protocols and study designs according to the research problem. The aim of this review is to present basic aspects for the start of a quantitative research in dentistry.It presents the topics necessary to transform a research problem to a question with clinical approach. Then, concepts about finding relevant scientific articles in the electroni...

  16. A Preliminary Study on Gender Differences in Studying Systems Analysis and Design

    Science.gov (United States)

    Lee, Fion S. L.; Wong, Kelvin C. K.

    2017-01-01

    Systems analysis and design is a crucial task in system development and is included in a typical information systems programme as a core course. This paper presented a preliminary study on gender differences in studying a systems analysis and design course of an undergraduate programme. Results indicated that male students outperformed female…

  17. Genetic epidemiology of tuberculosis susceptibility: impact of study design.

    Science.gov (United States)

    Stein, Catherine M

    2011-01-20

    Several candidate gene studies have provided evidence for a role of host genetics in susceptibility to tuberculosis (TB). However, the results of these studies have been very inconsistent, even within a study population. Here, we review the design of these studies from a genetic epidemiological perspective, illustrating important differences in phenotype definition in both cases and controls, consideration of latent M. tuberculosis infection versus active TB disease, population genetic factors such as population substructure and linkage disequilibrium, polymorphism selection, and potential global differences in M. tuberculosis strain. These considerable differences between studies should be accounted for when examining the current literature. Recommendations are made for future studies to further clarify the host genetics of TB.

  18. Preliminary Design Study of the Hollow Electron Lens for LHC

    CERN Document Server

    Perini, Diego; CERN. Geneva. ATS Department

    2017-01-01

    A Hollow Electron Lens (HEL) has been proposed in order to improve performance of halo control and collimation in the Large Hadron Collider in view of its High Luminosity upgrade (HL-LHC). The concept is based on a beam of electrons that travels around the protons for a few meters. The electron beam is produced by a cathode and then guided by a strong magnetic field generated by a set of superconducting solenoids. The first step of the design is the definition of the magnetic fields that drive the electron trajectories. The estimation of such trajectories by means of a dedicated MATLAB® tool is presented. The influence of the main geometrical and electrical parameters are analysed and discussed. Then, the main mechanical design choices for the solenoids, cryostats gun and collector are described. The aim of this paper is to provide an overview of the preliminary design of the Electron Lens for LHC. The methods used in this study also serve as examples for future mechanical and integration designs of similar ...

  19. A designed screening study with prespecified combinations of factor settings

    Energy Technology Data Exchange (ETDEWEB)

    Anderson-cook, Christine M [Los Alamos National Laboratory; Robinson, Timothy J [U. WYOMING

    2009-01-01

    In many applications, the experimenter has limited options about what factor combinations can be chosen for a designed study. Consider a screening study for a production process involving five input factors whose levels have been previously established. The goal of the study is to understand the effect of each factor on the response, a variable that is expensive to measure and results in destruction of the part. From an inventory of available parts with known factor values, we wish to identify a best collection of factor combinations with which to estimate the factor effects. Though the observational nature of the study cannot establish a causal relationship involving the response and the factors, the study can increase understanding of the underlying process. The study can also help determine where investment should be made to control input factors during production that will maximally influence the response. Because the factor combinations are observational, the chosen model matrix will be nonorthogonal and will not allow independent estimation of factor effects. In this manuscript we borrow principles from design of experiments to suggest an 'optimal' selection of factor combinations. Specifically, we consider precision of model parameter estimates, the issue of replication, and abilities to detect lack of fit and to estimate two-factor interactions. Through an example, we present strategies for selecting a subset of factor combinations that simultaneously balance multiple objectives, conduct a limited sensitivity analysis, and provide practical guidance for implementing our techniques across a variety of quality engineering disciplines.

  20. Design

    DEFF Research Database (Denmark)

    Volf, Mette

    This publication is unique in its demystification and operationalization of the complex and elusive nature of the design process. The publication portrays the designer’s daily work and the creative process, which the designer is a part of. Apart from displaying the designer’s work methods...... and design parameters, the publication shows examples from renowned Danish design firms. Through these examples the reader gets an insight into the designer’s reality....

  1. Interim Design Report for the International Design Study for a Neutrino Factory

    Energy Technology Data Exchange (ETDEWEB)

    Choubey, S.; Gandhi, R.; Goswami, S.; /Harish-Chandra Res. Inst.; Berg, J.S.; Fernow, R.; Gallardo, J.C.; Gupta, R.; Kirk, H.; Simos, N.; Souchlas, N.; /Brookhaven; Ellis, M.; /Brunel U. /CERN /Durham U., IPPP /Fermilab /Geneva U. /Glasgow U. /Heidelberg, Max Planck Inst. /Imperial Coll., London /Jefferson Lab /Saha Inst.

    2011-10-01

    The starting point for the International Design Study for the Neutrino Factory (the IDS-NF) was the output of the earlier International Scoping Study for a future Neutrino Factory and super-beam facility (the ISS). The accelerator facility described in section 2 incorporates the improvements that have been derived from the substantial amount of work carried out within the Accelerator Working Group. Highlights of these improvements include: (1) Initial concepts for the implementation of the proton driver at each of the three example sites, CERN, FNAL, and RAL; (2) Detailed studies of the energy deposition in the target area; (3) A reduction in the length of the muon beam phase-rotation and bunching systems; (4) Detailed analyses of the impact of the risk that stray magnetic field in the accelerating cavities in the ionization cooling channel will reduce the maximum operating gradient. Several alternative ionization-cooling lattices have been developed as fallback options to mitigate this technical risk; (5) Studies of particle loss in the muon front-end and the development of strategies to mitigate the deleterious effects of such losses; (6) The development of more complete designs for the muon linac and re-circulating linacs; (7) The development of a design for the muon FFAG that incorporates insertions for injection and extraction; and (8) Detailed studies of diagnostics in the decay ring. Other sub-systems have undergone a more 'incremental' evolution; an indication that the design of the Neutrino Factory has achieved a degree of maturity. The design of the neutrino detectors described in section 3 has been optimized and the Detector Working Group has made substantial improvements to the simulation and analysis of the Magnetized Iron Neutrino Detector (MIND) resulting in an improvement in the overall neutrino-detection efficiency and a reduction in the neutrino-energy threshold. In addition, initial consideration of the engineering of the MIND has

  2. On the proper study design applicable to experimental balneology

    Science.gov (United States)

    Varga, Csaba

    2016-08-01

    The simple message of this paper is that it is the high time to reevaluate the strategies and optimize the efforts for investigation of thermal (spa) waters. Several articles trying to clear mode of action of medicinal waters have been published up to now. Almost all studies apply the unproven hypothesis, namely the inorganic ingredients are in close connection with healing effects of bathing. Change of paradigm would be highly necessary in this field taking into consideration the presence of several biologically active organic substances in these waters. A successful design for experimental mechanistic studies is approved.

  3. On the proper study design applicable to experimental balneology.

    Science.gov (United States)

    Varga, Csaba

    2016-08-01

    The simple message of this paper is that it is the high time to reevaluate the strategies and optimize the efforts for investigation of thermal (spa) waters. Several articles trying to clear mode of action of medicinal waters have been published up to now. Almost all studies apply the unproven hypothesis, namely the inorganic ingredients are in close connection with healing effects of bathing. Change of paradigm would be highly necessary in this field taking into consideration the presence of several biologically active organic substances in these waters. A successful design for experimental mechanistic studies is approved.

  4. Designing a Medical Tourism Website: A Qualitative Study

    Science.gov (United States)

    SAMADBEIK, Mahnaz; ASADI, Heshmatollah; MOHSENI, Mohammad; TAKBIRI, Afsaneh; MOOSAVI, Ahmad; GARAVAND, Ali

    2017-01-01

    Background: Informing plays a prominent role in attracting medical tourists. The enjoyment of proper medical information systems is one of the most important tools for the attraction of medical tourists. Iran’s ability in designing and implementing information networks has remained largely unknown. The current study aimed to explore information needs for designing a medical tourism website. Methods: This qualitative study was conducted in 2015 for designing Hospital Medical-Tourism Website (HMTW). A purposive sampling method was used and data were gathered using a semi-structured questionnaire. Totally, 12 faculty members and experts in the field of medical tourism were interviewed. Data were analyzed using the MAXQDA10 software. Results: Totally 41 sub-themes and 10 themes were identified. The themes included the introduction of hospital, general guide for patients, tourism information, information related to physicians in hospital, costs, treatment follow-up, online hospital appointment scheduling in website, statistics and news of hospital medical tourism, photo gallery and contacts. Among the themes, the participants highly emphasized four themes including costs (100%), tourism information (91.6%), information related to physicians in hospital, (83.3%) and treatment follow-up (83.3%). Conclusion: This profitable industry can be developed through considering information requirements for hospital medical tourism website. PMID:28451562

  5. Designing a Medical Tourism Website: A Qualitative Study.

    Science.gov (United States)

    Samadbeik, Mahnaz; Asadi, Heshmatollah; Mohseni, Mohammad; Takbiri, Afsaneh; Moosavi, Ahmad; Garavand, Ali

    2017-02-01

    Informing plays a prominent role in attracting medical tourists. The enjoyment of proper medical information systems is one of the most important tools for the attraction of medical tourists. Iran's ability in designing and implementing information networks has remained largely unknown. The current study aimed to explore information needs for designing a medical tourism website. This qualitative study was conducted in 2015 for designing Hospital Medical-Tourism Website (HMTW). A purposive sampling method was used and data were gathered using a semi-structured questionnaire. Totally, 12 faculty members and experts in the field of medical tourism were interviewed. Data were analyzed using the MAXQDA10 software. Totally 41 sub-themes and 10 themes were identified. The themes included the introduction of hospital, general guide for patients, tourism information, information related to physicians in hospital, costs, treatment follow-up, online hospital appointment scheduling in website, statistics and news of hospital medical tourism, photo gallery and contacts. Among the themes, the participants highly emphasized four themes including costs (100%), tourism information (91.6%), information related to physicians in hospital, (83.3%) and treatment follow-up (83.3%). This profitable industry can be developed through considering information requirements for hospital medical tourism website.

  6. Applying Semiotic Theories to Graphic Design Education: An Empirical Study on Poster Design Teaching

    Science.gov (United States)

    Yang, Chao-Ming; Hsu, Tzu-Fan

    2015-01-01

    The rationales behind design are dissimilar to those behind art. Establishing an adequate theoretical foundation for conducting design education can facilitate scientising design methods. Thus, from the perspectives of the semiotic theories proposed by Saussure and Peirce, we investigated graphic design curricula by performing teaching…

  7. Destined to Design? How and Why Australian Women Choose to Study Industrial Design

    Science.gov (United States)

    Lockhart, Cathy; Miller, Evonne

    2016-01-01

    Despite over three decades of legislation and initiatives designed to tackle the traditional gender divide in the science, technology and design fields, only a quarter of the registered architects in Australia are women. There are no statistics available for other design disciplines, with little known about why women choose design as a career path…

  8. Destined to Design? How and Why Australian Women Choose to Study Industrial Design

    Science.gov (United States)

    Lockhart, Cathy; Miller, Evonne

    2016-01-01

    Despite over three decades of legislation and initiatives designed to tackle the traditional gender divide in the science, technology and design fields, only a quarter of the registered architects in Australia are women. There are no statistics available for other design disciplines, with little known about why women choose design as a career path…

  9. A Competence-Based Curriculum Design for Entrepreneurship Study Program

    Directory of Open Access Journals (Sweden)

    Priska J.R. Siagian

    2011-08-01

    Full Text Available Indonesia is affected by global crisis. Increasing the number of entrepreneurs is one of many solutions to increase the economic growth in Indonesia. The number of entrepreneurs in Indonesia to leverage the economic growth is still limited. Entrepreneurs can be prepared through an Entrepreneurship Study Program. Entrepreneurship Study Program attempts to create qualified entrepreneurs who have relevant competences. In order to create a qualified entrepreneurs, the Entrepreneurial Studies Program requires a competency-based curriculum that will support the educational process and provide all the necessary to become future entrepreneurs who can survive through a global challenge. This research aims to design a competence-based curriculum for entrepreneurial study and uses Quality Function Deployment (QFD as the major tool to design the competence-based curriculum. From the QFD process, this research finds core and elective courses for the Entrepreneurship Study Program. The result shows the competences covered by the courses and sequence, credits, and teaching methods for each course. The competences prepared the potential entrepreneurs can be achieved through specific courses which can be acquired within 8 semesters.

  10. Study on Aerodynamic Design Optimization of Turbomachinery Blades

    Institute of Scientific and Technical Information of China (English)

    Naixing CHEN; Hongwu ZHANG; Weiguang HUANG; Yanji XU

    2005-01-01

    This paper describes the study on aerodynamics design optimization of turbomachinery blading developed by the authors at the Institute of Engineering Thermophysics, Chinese Academy of Sciences, during the recent few years. The present paper describes the aspects mainly on how to use a rapid approach of profiling a 3D blading and of grid generation for computation, a fast and accurate viscous computation method and an appropriate optimization methodology_ including a blade parameterization algorithm to optimize turbomachinery blading aerodynamically. Any blade configuration can be expressed by three curves, they are the camber lines, the thickness distributions and the radial stacking line, and then the blade geometry can be easily parameterized by a number of parameters with three polynomials. A gradient-based parameterization analytical method and a response surface method were applied herein for blade optimization. It was found that the optimization process provides reliable design for turbomachinery with reasonable computing time.

  11. 3D CAD for concept design - a case study

    Directory of Open Access Journals (Sweden)

    S.K. Mandal

    2013-07-01

    Full Text Available Generally for any new design initially a concept layout in 2D CAD is generated. But sometimes if the geometry of product becomes complicated, then 3D CAD model is preferred. Because 3D CAD model can give us a complete all side view at a time like a real product, but in a virtual world. The present case study will show the utilization of 3D CAD at the concept design stage of a complicated shaped product for a new system. This will also give an idea about cost and time comparison. Thus this paper will describe about the importance of 3D CAD tools for product development. 

  12. Study on core design for reduced-moderation water reactors

    Energy Technology Data Exchange (ETDEWEB)

    Okubo, Tsutomu [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2002-12-01

    The Reduced-Moderation Water Reactor (RMWR) is a water-cooled reactor with the harder neutron spectrum comparing with the LWR, resulting from low neutron moderation due to reduced water volume fraction. Based on the difference from the spectrum from the LWR, the conversion from U-238 to Pu-239 is promoted and the new cores preferable to effective utilization of uranium resource can be possible Design study of the RMWR core started in 1997 and new four core concepts (three BWR cores and one PWR core) are recently evaluated in terms of control rod worths, plutonium multiple recycle, high burnup and void coefficient. Comparative evaluations show needed incorporation of control rod programming and simplified PUREX process as well as development of new fuel cans for high burnup of 100 GW-d/t. Final choice of design specifications will be made at the next step aiming at realization of the RMWR. (T. Tanaka)

  13. Design study of an upgraded charge breeder for ISOLDE

    CERN Document Server

    Shornikov, A; Wenander, F; Pikin, A

    2013-01-01

    In this work we present our progress in the design study of a new Electron Beam Ion Source (EBIS) to be installed as a charge breeder for reacceleration of rare ions at ISOLDE. The work is triggered by the HIE-ISOLDE upgrade {[}1] and the planned TSR@ISOLDE project {[}2]. To fulfill the requests of the user community the new EBIS should reach an electron beam density of 10(4) A/cm(2) at electron energies up to 150 key and, provide UHV environment and ion cooling in the breeding region to ensure confinement of the ions long enough to reach the requested charge states. We report on the established design parameters and first prototyping steps towards production and testing of suitable equipment. (C) 2013 Elsevier B.V. All rights reserved.

  14. Design Methodology And Performance Studies Of A Flexible Electrotextile Surface

    Directory of Open Access Journals (Sweden)

    Kayacan Ozan

    2015-09-01

    Full Text Available ‘The smart textiles’ concept has to develop products based not only on design, fashion and comfort but also in terms of functions. The novel electro-textiles in the market open up new trends in smart and interactive gadgets. ‘Easy to care and durability’ properties are among the most important features of these products. On the other hand, wearable electronic knitwear has been gaining the attention of both researchers and industrial sectors. Combining knitting technology with electronics may become a dominant trend in the future because of the wide application possibilities. This research is concerned primarily with the design methodology of knitted fabrics containing electrically conductive textiles and especially in-use performance studies. The structural characteristics of the fabrics have been evaluated to enhance the performance properties.

  15. Research in dentistry: Question, search and studies design.

    Directory of Open Access Journals (Sweden)

    Pedro Aravena

    2012-12-01

    Full Text Available Evidence-based dentistry (EBD concept has caused great impact and interest in the field of dentistry. For its development is important to use research protocols and study designs according to the research problem. The aim of this review is to present basic aspects for the start of a quantitative research in dentistry.It presents the topics necessary to transform a research problem to a question with clinical approach. Then, concepts about finding relevant scientific articles in the electronic databases available on the Internet. It also presents observational and experimental research designs, their classification and topics for your choice. These elements represents simple and clear recommendations for research in dentistry.

  16. Five Principles for MOOC Design: With a Case Study

    Directory of Open Access Journals (Sweden)

    John R. Drake

    2015-05-01

    Full Text Available New web technologies have enabled online education to take on a massive scale, prompting many universities to create massively open online courses (MOOCs that take advantage of these technologies in a seemingly effortless manner. Designing a MOOC, however, is anything but trivial. It involves developing content, learning activities, and assessments to accommodate both the massiveness and openness of the course. To design an effective MOOC, instructors need to integrate both pedagogical and information systems theory. In this paper, we present a case study of a MOOC grant and a series of decisions made in its development. These decisions, when paired with the theoretical framework, suggest five principles – meaningful, engaging, measurable, accessible, and scalable – may be applicable to future MOOC development projects.

  17. Evaluating disease management programme effectiveness: an introduction to the regression discontinuity design.

    Science.gov (United States)

    Linden, Ariel; Adams, John L; Roberts, Nancy

    2006-04-01

    Although disease management (DM) has been in existence for over a decade, there is still much uncertainty as to its effectiveness in improving health status and reducing medical cost. The main reason is that most programme evaluations typically follow weak observational study designs that are subject to bias, most notably selection bias and regression to the mean. The regression discontinuity (RD) design may be the best alternative to randomized studies for evaluating DM programme effectiveness. The most crucial element of the RD design is its use of a 'cut-off' score on a pre-test measure to determine assignment to intervention or control. A valuable feature of this technique is that the pre-test measure does not have to be the same as the outcome measure, thus maximizing the programme's ability to use research-based practice guidelines, survey instruments and other tools to identify those individuals in greatest need of the programme intervention. Similarly, the cut-off score can be based on clinical understanding of the disease process, empirically derived, or resource-based. In the RD design, programme effectiveness is determined by a change in the pre-post relationship at the cut-off point. While the RD design is uniquely suitable for DM programme evaluation, its success will depend, in large part, on fundamental changes being made in the way DM programmes identify and assign individuals to the programme intervention.

  18. Bridging From Goals to Tasks with Design Study Analysis Reports.

    Science.gov (United States)

    Lam, Heidi; Tory, Melanie; Munzner, Tamara

    2017-08-31

    Visualization researchers and practitioners engaged in generating or evaluating designs are faced with the difficult problem of transforming the questions asked and actions taken by target users from domain-specific language and context into more abstract forms. Existing abstract task classifications aim to provide support for this endeavour by providing a carefully delineated suite of actions. Our experience is that this bottom-up approach is part of the challenge: low-level actions are difficult to interpret without a higher-level context of analysis goals and the analysis process. To bridge this gap, we propose a framework based on analysis reports derived from open-coding 20 design study papers published at IEEE InfoVis 2009-2015, to build on the previous work of abstractions that collectively encompass a broad variety of domains. The framework is organized in two axes illustrated by nine analysis goals. It helps situate the analysis goals by placing each goal under axes of specificity (Explore, Describe, Explain, Confirm) and number of data populations (Single, Multiple). The single-population types are Discover Observation, Describe Observation, Identify Main Cause, and Collect Evidence. The multiple-population types are Compare Entities, Explain Differences, and Evaluate Hypothesis. Each analysis goal is scoped by an input and an output and is characterized by analysis steps reported in the design study papers. We provide examples of how we and others have used the framework in a top-down approach to abstracting domain problems: visualization designers or researchers first identify the analysis goals of each unit of analysis in an analysis stream, and then encode the individual steps using existing task classifications with the context of the goal, the level of specificity, and the number of populations involved in the analysis.

  19. Study and Redefining Beneficiary Participation in Process Of House Design

    Directory of Open Access Journals (Sweden)

    Monshizadeh Morteza

    2016-01-01

    Full Text Available Since housing has a special place in human life and his physical, psychological and interactions, so in addition the unity of humans, multiplicity and diversity of them must be considered. This possible only by beneficiary participation in the design process, but because society has different economic and social texture and classes; and settling suit because of the time and place of special indexes are entitled, so prepare a comprehensive model includes the testimony and circumstances; identify factors influencing participation optimum need to selection population and certain species of private construction. Standard tool to study topic does not exist, so in order to produce tools using qualitative research methods; interpretation - historical correlation to extract components and variables and their effects on each other and enjoyed target table Content consisting of four domains of general knowledge - specialized knowledge of participation - participation mechanisms and factors influencing participation achieved. Extracted factors are: the initial formation of partnership - partnership executive process - the role of participant - optimal participation; by study and analyze the theoretical model. Due to history and social aspects; cultural participation in Shiraz; promote scientific and participatory approach designed to make operating housing; bed and new horizons of development of facilities and areas in the design of residential environment created and due consultation and decision making in addition to beneficiary participation to promote optimum utility of space; mutual flexibility and utilization of space; increase fixation and motivation will lead beneficiary reside” and the main question: “how is the model of scientific position optimal participation planning instrument in private housing in the city of Shiraz, in the process of design, implementation and use”.

  20. Study of Object Oriented Analysis and Design Approach

    Directory of Open Access Journals (Sweden)

    Sunil K. Pandey

    2011-01-01

    Full Text Available Problem statement: Object and component technologies, rapidly maturing branches of information technology, have been becoming pervasive elements of systems development, especially the recently popular Internet applications and thus leading to increased complexity and at the same time broader range of applications. Approach: This needs to be understood in order to maximize its benefits and applications with consistent results. However, mainstream Object Oriented Systems Development (OOSD, consisting of Object Oriented Analysis and Design (OOAD and Object- Oriented Programming (OOP, has a history of difficulties and is still struggling to gain prevalent acceptance. Results: There have been number of studies and experiments conducted by experts and researchers in the past which provides a solid base to take up this study and look into various intricacies present. There have been several studies and focused efforts in this direction which laid down the basis for a segment of people to form the opinion as “technology adoption is mostly the result of marketing forces, not scientific evidence” whereas there have been another segment that believes that object technology is “still long on hype and short on results ...”. The gurus of OOSD continue to tout its vast superiority over conventional systems development, even to the extent of developing a unified software development process. Conclusion: The advocates of OOSD claim many advantages including easier modeling, increased code reuse, higher system quality and easier maintenance. It is well understood that analysis and design are extremely critical aspects of successful systems development especially in the case of OOSD. As the development of any successful information system must begin with a well-conceived and implemented analysis and design, this study will focus on the most recent empirical evidence on the pros and cons of OOAD.

  1. Inflammation and Exercise (INFLAME): study rationale, design, and methods

    Science.gov (United States)

    Thompson, Angela; Mikus, Catherine; Rodarte, Ruben Q.; Distefano, Brandy; Priest, Elisa L.; Sinclair, Erin; Earnest, Conrad P.; Blair, Steven N.; Church, Timothy S.

    2008-01-01

    Purpose The INFLAME study is designed to determine the effect of exercise training on elevated high-sensitivity C-Reactive Protein (CRP) concentrations in initially sedentary women and men. Methods INFLAME will recruit 170 healthy, sedentary women and men with elevated CRP (≥2.0 mg/L) to be randomized to either an exercise group or non-exercise control group. Exercising individuals will participate in four months of supervised aerobic exercise with a total energy expenditure of 16 kcal • kg−1 • week−1 (KKW). Exercise intensity will be 60–80% of maximal oxygen consumption (VO2 max). Outcome The primary outcome will be change in plasma CRP concentration. Secondary outcomes include visceral adiposity, the cytokines IL-6 and TNF-α, and heart rate variability (HRV) in order to examine potential biological mechanisms whereby exercise might affect CRP concentrations. Summary INFLAME will help us understand the effects of moderate to vigorous exercise on CRP concentrations in sedentary individuals. To our knowledge this will be the largest training study specifically designed to examine the effect of exercise on CRP concentrations. This study has the potential to influence therapeutic applications since CRP measurement is becoming an important clinical measurement in Coronary Heart Disease risk assessment. This study will also contribute to the limited body of literature examining the effect of exercise on the variables of visceral adiposity, cytokines, and heart rate variability. PMID:18024231

  2. Accelerating Vaccine Formulation Development Using Design of Experiment Stability Studies.

    Science.gov (United States)

    Ahl, Patrick L; Mensch, Christopher; Hu, Binghua; Pixley, Heidi; Zhang, Lan; Dieter, Lance; Russell, Ryann; Smith, William J; Przysiecki, Craig; Kosinski, Mike; Blue, Jeffrey T

    2016-10-01

    Vaccine drug product thermal stability often depends on formulation input factors and how they interact. Scientific understanding and professional experience typically allows vaccine formulators to accurately predict the thermal stability output based on formulation input factors such as pH, ionic strength, and excipients. Thermal stability predictions, however, are not enough for regulators. Stability claims must be supported by experimental data. The Quality by Design approach of Design of Experiment (DoE) is well suited to describe formulation outputs such as thermal stability in terms of formulation input factors. A DoE approach particularly at elevated temperatures that induce accelerated degradation can provide empirical understanding of how vaccine formulation input factors and interactions affect vaccine stability output performance. This is possible even when clear scientific understanding of particular formulation stability mechanisms are lacking. A DoE approach was used in an accelerated 37(°)C stability study of an aluminum adjuvant Neisseria meningitidis serogroup B vaccine. Formulation stability differences were identified after only 15 days into the study. We believe this study demonstrates the power of combining DoE methodology with accelerated stress stability studies to accelerate and improve vaccine formulation development programs particularly during the preformulation stage. Copyright © 2016 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

  3. Status of PEP-X Light Source Design Study

    Energy Technology Data Exchange (ETDEWEB)

    Bane, K.L.F.; Bertsche, K.J.; Cai, Y.; Chao, A.; Huang, X.; Jiao, Y.; Ng, C.-K.; Nosochkov, Y.; Novokhatski, A.; Rivetta, C.H.; Safranek, J.A.; Stupakov, G.V.; Wang, L.; Wang, M.-H.; Xiao, L.; /SLAC; Hettel, R.O.; /SLAC; Rabedeau, T.; /SLAC

    2011-12-14

    The SLAC Beam Physics group and other SLAC collaborators continue to study options for implementing a near diffraction-limited ring-based light source in the 2.2-km PEP-II tunnel that will serve the SSRL scientific program in the future. The study team has completed the baseline design for a 4.5-GeV storage ring having 160 pm-rad emittance with stored beam current of 1.5 A, providing >10{sup 22} brightness for multi-keV photon beams from 3.5-m undulator sources. The team has also investigated possible 5-GeV ERL configurations which, similar to the Cornell and KEK ERL plans, would have {approx}30 pm-rad emittance with 100 mA current, and {approx}10 pm-rad emittance with 25 mA or less. Now a 4.5-GeV 'ultimate' storage ring having emittance similar to the ERL and operating with {approx}200 mA is under study. An overview of the progress of the PEP-X design study and SSRL's plans for defining performance parameters that will guide the choice of ring options is presented.

  4. Study on Design Methodology of Mass Customization Products

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Based on introduction characteristics and classific at ion of Mass Customization (MC), the paper expounds foundations and design me thods of MC. The foundations of MC production are standardization, seriation and normality of production, guiding thought of Concurrent Engineering (CE), ap plication of CAD/CAM technology and etc. And design methods of MC products are d esign for product family, modular design, parameterization CAD, variant design, design for manufacturing (DFM) and design by customers. ...

  5. Designing for Diverse Learning: Case Study of Place-Based Learning in Design and Technologies Pre-Service Teacher Education

    Science.gov (United States)

    Best, Marnie; MacGregor, Denise; Price, Deborah

    2017-01-01

    Place-based learning experiences in Design and Technologies education connect people and place with design processes and products. Drawing on place-based learning, this case study shares the experiences of eight final year pre-service Design and Technologies education students from the University of South Australia as they collaborated with…

  6. Conceptual design study of the GSI electron-nucleon collider

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    Design concepts, beam-beam instability, ion bunch cooling, intrabeam scattering, conventional collective effects, lattice design, polarization control, injection chain, basic technical systems, cost estimations, time schedule.

  7. Conceptual design study of an improved automotive gas turbine powertrain

    Science.gov (United States)

    Wagner, C. E. (Editor); Pampreen, R. C. (Editor)

    1979-01-01

    Automotive gas turbine concepts with significant technological advantages over the spark ignition (SI) engine were assessed. Possible design concepts were rated with respect to fuel economy and near-term application. A program plan which outlines the development of the improved gas turbine (IGT) concept that best met the goals and objectives of the study identifies the research and development work needed to meet the goal of entering a production engineering phase by 1983. The fuel economy goal is to show at least a 20% improvement over a conventional 1976 SI engine/vehicle system. On the basis of achieving the fuel economy goal, of overall suitability to mechanical design, and of automotive mass production cost, the powertrain selected was a single-shaft engine with a radial turbine and a continuously variable transmission (CVT). Design turbine inlet temperature was 1150 C. Reflecting near-term technology, the turbine rotor would be made of an advanced superalloy, and the transmission would be a hydromechanical CVT. With successful progress in long-lead R&D in ceramic technology and the belt-drive CVT, the turbine inlet temperature would be 1350 C to achieve near-maximum fuel economy.

  8. Distilling Design Patterns From Agile Curation Case Studies

    Science.gov (United States)

    Benedict, K. K.; Lenhardt, W. C.; Young, J. W.

    2016-12-01

    In previous work the authors have argued that there is a need to take a new look at the data management lifecycle. Our core argument is that the data management lifecycle needs to be in essence deconstructed and rebuilt. As part of this process we also argue that much can be gained from applying ideas, concepts, and principles from agile software development methods. To be sure we are not arguing for a rote application of these agile software approaches, however, given various trends related to data and technology, it is imperative to update our thinking about how to approach the data management lifecycle, recognize differing project scales, corresponding variations in structure, and alternative models for solving the problems of scientific data curation. In this paper we will describe what we term agile curation design patterns, borrowing the concept of design patterns from the software world and we will present some initial thoughts on agile curation design patterns as informed by a sample of data curation case studies solicited from participants in agile data curation meeting sessions conducted in 2015-16.

  9. Optimization Studies of the FERMI at ELETTRA FEL Design

    CERN Document Server

    De Ninno, G

    2005-01-01

    The FERMI at ELETTRA project at Sincotrone Trieste involves two FEL's, each based upon the principle of a seeded harmonic cascade and using the existing ELETTRA injection linac at 1.2 GeV beam energy. Scheduled to be completed in 2008, FEL-1 will operate in the 40-100 nm wavelength range and will involve one stage of harmonic up-conversion. The second phase, FEL-2, will begin operation two years later in the 10-40 nm wavelength range and will involve two cascade stages. FEL design assumes wavelength tunability over the full wavelength range and polarization tunability of the output radiation including helical polarization. The design considers focusing properties and segmentation of realizable undulators and available input seed lasers. We discuss how the interplay between various limitations and self-consistent accelerator simulations [1,2] have led to our current design. We present results of simulations using GENESIS and GINGER simulation codes including studies of various shot-to-shot fluctuations and und...

  10. Building qualitative study design using nursing's disciplinary epistemology.

    Science.gov (United States)

    Thorne, Sally; Stephens, Jennifer; Truant, Tracy

    2016-02-01

    To discuss the implications of drawing on core nursing knowledge as theoretical scaffolding for qualitative nursing enquiry. Although nurse scholars have been using qualitative methods for decades, much of their methodological direction derives from conventional approaches developed for answering questions in the social sciences. The quality of available knowledge to inform practice can be enhanced through the selection of study design options informed by an appreciation for the nature of nursing knowledge. Discussion paper. Drawing on the body of extant literature dealing with nursing's theoretical and qualitative research traditions, we consider contextual factors that have shaped the application of qualitative research approaches in nursing, including prior attempts to align method with the structure and form of disciplinary knowledge. On this basis, we critically reflect on design considerations that would follow logically from core features associated with a nursing epistemology. The substantive knowledge used by nurses to inform their practice includes both aspects developed at the level of the general and also that which pertains to application in the unique context of the particular. It must be contextually relevant to a fluid and dynamic healthcare environment and adaptable to distinctive patient conditions. Finally, it must align with nursing's moral mandate and action imperative. Qualitative research design components informed by nursing's disciplinary epistemology will help ensure a logical line of reasoning in our enquiries that remains true to the nature and structure of practice knowledge. © 2015 John Wiley & Sons Ltd.

  11. Theoretical design study of the MSFC wind-wheel turbine

    Science.gov (United States)

    Frost, W.; Kessel, P. A.

    1982-01-01

    A wind wheel turbine (WWT) is studied. Evaluation of the probable performance, possible practical applications, and economic viability as compared to other conventional wind energy systems is discussed. The WWT apparatus is essentially a bladed wheel which is directly exposed to the wind on the upper half and exposed to wind through multiple ducting on the lower half. The multiple ducts consist of a forward duct (front concentrator) and two side ducts (side concentrators). The forced rotation of the wheel is then converted to power through appropriate subsystems. Test results on two simple models, a paper model and a stainless steel model, are reported. Measured values of power coefficients over wind speeds ranging from 4 to 16 m/s are given. An analytical model of a four bladed wheel is also developed. Overall design features of the wind turbine are evaluated and discussed. Turbine sizing is specified for a 5 and 25 kW machine. Suggested improvements to the original design to increase performance and performance predictions for an improved WWT design are given.

  12. A Study on Plant Selection for Green Building Design

    Directory of Open Access Journals (Sweden)

    Izudinshah Abd. Wahab

    2013-02-01

    Full Text Available Previous researches show that incorporating natural elements in design has proven a significant result in balancing building indoor environment. Using plant as part of the design has been widely accepted to contribute good thermal impact as shown in bioclimatic design, green roofing system and living wall elements. As there are so many species of plants for selection, this research was carried out to analyze types of indoor plants that have the potential to contribute thermal comfort to their surrounding. Based on the fact that plant leaves are the part where transpiration and guttation take place, plants are categorized into seven types based on their leaves architecture. They were then tested on their impact on surrounding temperature and humidity. Result shows that Linear, Lanceolate and Oblong shaped leaves categories are good in lowering the relative humidity while the categories that are good in lowering the temperature are Linear, Lanceolate, Cordate and Oblong shaped leaves categories. The study was carried out through series of relative humidity and air temperature monitoring of several room casings that consist with the plants. Both relative humidity and air temperature of the rooms with plants were recorded lower compared with the one without plant. Different categories of plants do give good result in relative humidity and air temperature. Thus, with a good combination of plant installation inside or onto building, it may contribute towards providing a good thermal comfort to the occupants.

  13. Designing A Mixed Methods Study In Primary Care

    Science.gov (United States)

    Creswell, John W.; Fetters, Michael D.; Ivankova, Nataliya V.

    2004-01-01

    BACKGROUND Mixed methods or multimethod research holds potential for rigorous, methodologically sound investigations in primary care. The objective of this study was to use criteria from the literature to evaluate 5 mixed methods studies in primary care and to advance 3 models useful for designing such investigations. METHODS We first identified criteria from the social and behavioral sciences to analyze mixed methods studies in primary care research. We then used the criteria to evaluate 5 mixed methods investigations published in primary care research journals. RESULTS Of the 5 studies analyzed, 3 included a rationale for mixing based on the need to develop a quantitative instrument from qualitative data or to converge information to best understand the research topic. Quantitative data collection involved structured interviews, observational checklists, and chart audits that were analyzed using descriptive and inferential statistical procedures. Qualitative data consisted of semistructured interviews and field observations that were analyzed using coding to develop themes and categories. The studies showed diverse forms of priority: equal priority, qualitative priority, and quantitative priority. Data collection involved quantitative and qualitative data gathered both concurrently and sequentially. The integration of the quantitative and qualitative data in these studies occurred between data analysis from one phase and data collection from a subsequent phase, while analyzing the data, and when reporting the results. DISCUSSION We recommend instrument-building, triangulation, and data transformation models for mixed methods designs as useful frameworks to add rigor to investigations in primary care. We also discuss the limitations of our study and the need for future research. PMID:15053277

  14. Integrated learning in practical machine element design course: a case study of V-pulley design

    Science.gov (United States)

    Tantrabandit, Manop

    2014-06-01

    To achieve an effective integrated learning in Machine Element Design course, it is of importance to bridge the basic knowledge and skills of element designs. The multiple core learning leads the pathway which consists of two main parts. The first part involves teaching documents of which the contents are number of V-groove formulae, standard of V-grooved pulleys, and parallel key dimension's formulae. The second part relates to the subjects that the students have studied prior to participating in this integrated learning course, namely Material Selection, Manufacturing Process, Applied Engineering Drawing, CAD (Computer Aided Design) animation software. Moreover, an intensive cooperation between a lecturer and students is another key factor to fulfill the success of integrated learning. Last but not least, the students need to share their knowledge within the group and among the other groups aiming to gain knowledge of and skills in 1) the application of CAD-software to build up manufacture part drawings, 2) assembly drawing, 3) simulation to verify the strength of loaded pulley by method of Finite Element Analysis (FEA), 4) the software to create animation of mounting and dismounting of a pulley to a shaft, and 5) an instruction manual. The end product of this integrated learning, as a result of the above 1 to 5 knowledge and skills obtained, the participating students can create an assembly derived from manufacture part drawings and a video presentation with bilingual (English-Thai) audio description of Vpulley with datum diameter of 250 mm, 4 grooves, and type of groove: SPA.

  15. High flux isotope reactor cold source preconceptual design study report

    Energy Technology Data Exchange (ETDEWEB)

    Selby, D.L.; Bucholz, J.A.; Burnette, S.E. [and others

    1995-12-01

    In February 1995, the deputy director of Oak Ridge National Laboratory (ORNL) formed a group to examine the need for upgrades to the High Flux Isotope Reactor (HFIR) system in light of the cancellation of the Advanced Neutron Source Project. One of the major findings of this study was that there was an immediate need for the installation of a cold neutron source facility in the HFIR complex. The anticipated cold source will consist of a cryogenic LH{sub 2} moderator plug, a cryogenic pump system, a refrigerator that uses helium gas as a refrigerant, a heat exchanger to interface the refrigerant with the hydrogen loop, liquid hydrogen transfer lines, a gas handling system that includes vacuum lines, and an instrumentation and control system to provide constant system status monitoring and to maintain system stability. The scope of this project includes the development, design, safety analysis, procurement/fabrication, testing, and installation of all of the components necessary to produce a working cold source within an existing HFIR beam tube. This project will also include those activities necessary to transport the cold neutron beam to the front face of the present HFIR beam room. The cold source project has been divided into four phases: (1) preconceptual, (2) conceptual design and research and development (R and D), (3) detailed design and procurement, and (4) installation and operation. This report marks the conclusion of the preconceptual phase and establishes the concept feasibility. The information presented includes the project scope, the preliminary design requirements, the preliminary cost and schedule, the preliminary performance data, and an outline of the various plans for completing the project.

  16. Design and Numerical Parametric Study of Fractal Heat Exchanger

    OpenAIRE

    Huang, Zhiwei; Ling, Jiazhen; Hwang, Yunho; Aute, Vikrant; Radermacher, Reinhard

    2016-01-01

    Air-to-refrigerant heat exchangers are a main component in air-conditioning and heat pump systems and are therefore a topic of major research focus. Such heat exchangers, mainly made of fin-and-tube and microchannels, use fins to augment the heat transfer area of the air-side. Recently it has been shown that finless designs using ≤ 1 mm hydraulic diameter bare tubes can deliver better air-side heat transfer performance than conventional heat exchangers. In current study, a novel air-to-refr...

  17. Design Study on a New Separator for PEEM3

    CERN Document Server

    Wan, Weishi; Padmore, Howard A

    2005-01-01

    A new aberration-corrected Photoemission Electron Microscope, called PEEM3, is under development at the Advanced Light Source. The resolution and transmission improvement is realized by correcting the lowest order spherical and chromatic aberrations using an electron mirror. A separator is required to separate the incoming uncorrected electron beam to the mirror from the corrected outgoing electron beam to the projector column. In this paper, we present a design study of a new separator for PEEM3. The layout, the Gaussian optics, the analysis of aberrations and the tolerance on power supply stability and alignment errors are reported.

  18. Metamaterial Structure Design Optimization: A Study of the Cylindrical Cloak

    Science.gov (United States)

    2013-03-01

    energy. iv First, I wish to thank God and my savior, Jesus Christ , for the opportunity to study His creation. Next, a big thank-you goes to my loving wife...requirements to create a more physically realizable set of material parameters. 6 2.1 TO Cylindrical Cloak Originally , TO was conceived in an effort to avoid...TO method to designing a cloak consists of deforming the coordinate system such that the origin point is expanded into a boundary around an area to be

  19. Designing artificial enzymes from scratch: Experimental study and mesoscale simulation

    Science.gov (United States)

    Komarov, Pavel V.; Zaborina, Olga E.; Klimova, Tamara P.; Lozinsky, Vladimir I.; Khalatur, Pavel G.; Khokhlov, Alexey R.

    2016-09-01

    We present a new concept for designing biomimetic analogs of enzymatic proteins; these analogs are based on the synthetic protein-like copolymers. α-Chymotrypsin is used as a prototype of the artificial catalyst. Our experimental study shows that in the course of free radical copolymerization of hydrophobic and hydrophilic monomers the target globular nanostructures of a "core-shell" morphology appear in a selective solvent. Using a mesoscale computer simulation, we show that the protein-like globules can have a large number of catalytic centers located at the hydrophobic core/hydrophilic shell interface.

  20. Advanced vehicle concepts systems and design analysis studies

    Science.gov (United States)

    Waters, Mark H.; Huynh, Loc C.

    1994-01-01

    The work conducted by the ELORET Institute under this Cooperative Agreement includes the modeling of hypersonic propulsion systems and the evaluation of hypersonic vehicles in general and most recently hypersonic waverider vehicles. This work in hypersonics was applied to the design of a two-stage to orbit launch vehicle which was included in the NASA Access to Space Project. Additional research regarded the Oblique All-Wing (OAW) Project at NASA ARC and included detailed configuration studies of OAW transport aircraft. Finally, work on the modeling of subsonic and supersonic turbofan engines was conducted under this research program.

  1. Interaction between atoms and slow light: a design study

    CERN Document Server

    Zang, Xiaorun; Faggiani, Rémi; Gill, Christopher; Petrov, Plamen G; Hugonin, Jean-Paul; Bernon, Simon; Bouyer, Philippe; Boyer, Vincent; Lalanne, Philippe

    2015-01-01

    The emerging field of on-chip integration of nanophotonic devices and cold atoms offers extremely-strong and pure light-matter interaction schemes, which may have profound impact on quantum information science. In this context, a longstanding obstacle is to achieve strong interaction between single atoms and single photons, while at the same time trap atoms in vacuum at large separation distances from dielectric surfaces. In this letter, we study new waveguide geometries that challenge these conflicting objectives. The designed photonic crystal waveguide is expected to offer a good compromise, which additionally allow for easy manipulation of atomic clouds around the structure.

  2. Design Study of Fully Superconducting Wind Turbine Generators

    DEFF Research Database (Denmark)

    Song, Xiaowei (Andy); Mijatovic, Nenad; Jensen, Bogi Bech

    2015-01-01

    In this paper, two fully superconducting generators employing MgB2 armature winding, with YBCO and MgB2 field winding respectively, are presented and analyzed. The ac loss in armature winding is estimated, and a simple comparative study is carried out. The results show that both electromagnetic...... designs for fully superconducting generators are promising with respect to the power density. However, the cost of removing ac loss in armature winding is as high as $900 000. It is also noted that with the current price of YBCO tape, the generator employing MgB 2 field winding would have lower cost....

  3. A study of shock characterization for protective packaging design

    Science.gov (United States)

    Lye, S. W.; Teo, M. Y.; Lew, S. C.

    1995-06-01

    Cushioning buffers made of expandable polystyrene, a white polymeric granulated material, are commonly used to protect goods from damage. Current design practices tend to be simplistic and general, resulting in either overdesigned buffers or inadequate product protection. The objective of this paper is to identify the main parameters affecting shock absorption so that products can be better protected. An investigative study reveals that the types of impact surfaces, material densities, geometric features, and configurations contribute significantly to the amount of shock that a product experiences.

  4. Study of orbit correction for eRHIC FFAG design

    Energy Technology Data Exchange (ETDEWEB)

    Liu, C. [Brookhaven National Lab. (BNL), Upton, NY (United States); Hao, Y. [Brookhaven National Lab. (BNL), Upton, NY (United States); Litvinenko, V. [Brookhaven National Lab. (BNL), Upton, NY (United States); Meot, F. [Brookhaven National Lab. (BNL), Upton, NY (United States); Minty, M. [Brookhaven National Lab. (BNL), Upton, NY (United States); Ptitsyn, V. [Brookhaven National Lab. (BNL), Upton, NY (United States); Trbojevic, D. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2015-05-03

    The unique feature of the orbits in the eRHIC Fixed Field Alternating Gradient (FFAG) design is that multiple accelerating and decelerating bunches pass through the same magnets with different horizontal offsets. Therefore, it is critical for the eRHIC FFAG to correct multiple orbits in the same vacuum pipe for better spin transmission and alignment of colliding beams. In this report, the effects on orbits from multiple error sources will be studied. The orbit correction method will be described and results will be presented.

  5. Alpha low-level stored waste systems design study

    Energy Technology Data Exchange (ETDEWEB)

    Feizollahi, F.; Teheranian, B. [Morrison Knudson Corp., San Francisco, CA (United States). Environmental Services Div.; Quapp, W.J. [EG and G Idaho, Inc., Idaho Falls, ID (United States)

    1992-08-01

    The Stored Waste System Design Study (SWSDS), commissioned by the Waste Technology Development Department at the Idaho National Engineering Laboratory (INEL), examines relative life-cycle costs associated with three system concepts for processing the alpha low-level waste (alpha-LLW) stored at the Radioactive Waste Management Complex`s Transuranic Storage Area at the INEL. The three system concepts are incineration/melting; thermal treatment/solidification; and sort, treat, and repackage. The SWSDS identifies system functional and operational requirements and assesses implementability; effectiveness; cost; and demonstration, testing, and evaluation (DT&E) requirements for each of the three concepts.

  6. Alpha low-level stored waste systems design study

    Energy Technology Data Exchange (ETDEWEB)

    Feizollahi, F.; Teheranian, B. (Morrison Knudson Corp., San Francisco, CA (United States). Environmental Services Div.); Quapp, W.J. (EG and G Idaho, Inc., Idaho Falls, ID (United States))

    1992-08-01

    The Stored Waste System Design Study (SWSDS), commissioned by the Waste Technology Development Department at the Idaho National Engineering Laboratory (INEL), examines relative life-cycle costs associated with three system concepts for processing the alpha low-level waste (alpha-LLW) stored at the Radioactive Waste Management Complex's Transuranic Storage Area at the INEL. The three system concepts are incineration/melting; thermal treatment/solidification; and sort, treat, and repackage. The SWSDS identifies system functional and operational requirements and assesses implementability; effectiveness; cost; and demonstration, testing, and evaluation (DT E) requirements for each of the three concepts.

  7. Residuals and outliers in replicate design crossover studies.

    Science.gov (United States)

    Schall, Robert; Endrenyi, Laszlo; Ring, Arne

    2010-07-01

    Outliers in bioequivalence trials may arise through various mechanisms, requiring different interpretation and handling of such data points. For example, regulatory authorities might permit exclusion from analysis of outliers caused by product or process failure, while exclusion of outliers caused by subject-by-treatment interaction generally is not acceptable. In standard 2 x 2 crossover studies it is not possible to distinguish between relevant types of outliers based on statistical criteria alone. However, in replicate design (2-treatment, 4-period) crossover studies three types of outliers can be distinguished: (i) Subject outliers are usually unproblematic, at least regarding the analysis of bioequivalence, and may require no further action; (ii) Subject-by-formulation outliers may affect the outcome of the bioequivalence test but generally cannot simply be removed from analysis; and (iii) Removal of single-data-point outliers from analysis may be justified in certain cases. As a very simple but effective diagnostic tool for the identification and classification of outliers in replicate design crossover studies we propose to calculate and plot three types of residual corresponding to the three different types of outliers that can be distinguished. The residuals are obtained from four mutually orthogonal linear contrasts of the four data points associated with each subject. If preferred, outlier tests can be applied to the resulting sets of residuals after suitable standardization.

  8. Aragon workers’ health studydesign and cohort description

    Directory of Open Access Journals (Sweden)

    Casasnovas José A

    2012-06-01

    Full Text Available Abstract Background Spain, a Mediterranean country with relatively low rates of coronary heart disease, has a high prevalence of traditional cardiovascular risk factors and is experiencing a severe epidemic of overweight/obesity. We designed the Aragon Workers’ Health Study (AWHS to characterize the factors associated with metabolic abnormalities and subclinical atherosclerosis in a middle aged population in Spain free of clinical cardiovascular disease. The objective of this paper is to describe the study design, aims and baseline characteristics of participants in the AWHS. Methods/Design Longitudinal cohort study based on the annual health exams of 5,400 workers of a car assembly plant in Figueruelas (Zaragoza, Spain. Study participants were recruited during a standardized clinical exam in 2009–2010 (participation rate 95.6%. Study participants will undergo annual clinical exams and laboratory assays, and baseline and triennial collection of biological materials for biobanking and cardiovascular imaging exams (carotid, femoral and abdominal ultrasonography, coronary calcium score, and ankle-arm blood pressure index. Participants will be followed-up for 10 years. Results The average (SD age, body mass index, and waist circumference were 49.3 (8.7 years, 27.7 (3.6 kg/m2 and 97.2 (9.9 cm, respectively, among males (N = 5,048, and 40.8 (11.6 years, 24.4 (3.8 kg/m2, and 81.9 (9.9 cm, among females (N = 351. The prevalence of overweight, obesity, current smoking, hypertension, hypercholesterolemia, and diabetes were 55.0, 23.1, 37.1, 40.3, 75.0, and 7.4%, respectively, among males, and 23.7, 8.3, 45.0, 12.1, 59.5, and 0.6%, respectively, among females. In the initial 587 study participants who completed all imaging exams (94.5% male, the prevalence of carotid plaque, femoral plaque, coronary calcium score >1 to 100, and coronary calcium score >100 was 30.3, 56.9, 27.0, and 8.8%, respectively. 67.7% of study participants had at least

  9. Design of the sex hormones and physical exercise (SHAPE study

    Directory of Open Access Journals (Sweden)

    Peeters Petra HM

    2007-09-01

    Full Text Available Abstract Background Physical activity has been associated with a decreased risk for breast cancer. The biological mechanismn(s underlying the association between physical activity and breast cancer is not clear. Most prominent hypothesis is that physical activity may protect against breast cancer through reduced lifetime exposure to endogenous hormones either direct, or indirect by preventing overweight and abdominal adiposity. In order to get more insight in the causal pathway between physical activity and breast cancer risk, we designed the Sex Hormones and Physical Exercise (SHAPE study. Purpose of SHAPE study is to examine the effects of a 1-year moderate-to-vigorous intensity exercise programme on endogenous hormone levels associated with breast cancer among sedentary postmenopausal women and whether the amount of total body fat or abdominal fat mediates the effects. Methods/Design In the SHAPE study, 189 sedentary postmenopausal women, aged 50–69 years, are randomly allocated to an intervention or a control group. The intervention consists of an 1-year moderate-to-vigorous intensity aerobic and strenght training exercise programme. Partcipants allocated to the control group are requested to retain their habitual exercise pattern. Primary study parameters measured at baseline, at four months and at 12 months are: serum concentrations of endogenous estrogens, endogenous androgens, sex hormone binding globuline and insuline. Other study parameters include: amount of total and abdominal fat, weight, BMI, body fat distribution, physical fitness, blood pressure and lifestyle factors. Discussion This study will contribute to the body of evidence relating physical activity and breast cancer risk and will provide insight into possible mechanisms through which physical activity might be associated with reduced risk of breast cancer in postmenopausal women. Trial registration NCT00359060

  10. Workspace Design: A case study applying participatory design principles of healthy workplaces in an industrial setting

    DEFF Research Database (Denmark)

    Broberg, Ole

    2010-01-01

    in a case involving the design and implementation of a new mixing technology in an industrial plant. The case showed how the WSD concept can contribute to an engineering design process. The WSD team took the role as workspace designer and by the participatory workshops achieved an impact on the technology......The Danish Workspace Design (WSD) research program is aimed to develop and trial a potential new concept for ergonomists and other workplace consultants who are to engage in socio-technical design processes. The objective of this paper is to report on the trial of the workspace design concept...... project. In the role as workspace designer it was important for the WSD team to make sure that the achievements in the workshops were “transmitted” to and sustained in the ordinary engineering design process. In this case, it turned out that the artefacts such as a layout game board and documents...

  11. The design of serious games: a pedagogical experience inthe field of BA design studies

    Directory of Open Access Journals (Sweden)

    Joan Morales Moras

    2013-06-01

    Full Text Available Academic programs in Design have always faced the challenge of providing the best education in a sphere so changing as Design discipline itself. This is especially true within the current renewal of curricula derived from the implementation of the European Higher Education Area (EHEA and, to a much more general level, the adaptation of the discipline of Design to the new challenges posed by the Knowledge Society. In this context, we present the educational experience of a serious games design workshop, which has been conducted at the Universitat de Barcelona’s Design BA. This pedagogical activity emphasises on three aspects which we believe are fundamental to the current pedagogy of design: to give a more transverse view of this discipline, to value the role of Design as a means of innovation in today's Knowledge Society, and to rethink the social function of Design.

  12. Workspace Design: A case study applying participatory design principles of healthy workplaces in an industrial setting

    DEFF Research Database (Denmark)

    Broberg, Ole

    2010-01-01

    The Danish Workspace Design (WSD) research program is aimed to develop and trial a potential new concept for ergonomists and other workplace consultants who are to engage in socio-technical design processes. The objective of this paper is to report on the trial of the workspace design concept...... in a case involving the design and implementation of a new mixing technology in an industrial plant. The case showed how the WSD concept can contribute to an engineering design process. The WSD team took the role as workspace designer and by the participatory workshops achieved an impact on the technology...... project. In the role as workspace designer it was important for the WSD team to make sure that the achievements in the workshops were “transmitted” to and sustained in the ordinary engineering design process. In this case, it turned out that the artefacts such as a layout game board and documents...

  13. A Design Approach for Collaboration Processes: A Multi-Method Design Science Study in Collaboration Engineering

    NARCIS (Netherlands)

    Kolfschoten, G.L.; De Vreede, G.J.

    2009-01-01

    Collaboration Engineering is an approach for the design and deployment of repeatable collaboration processes that can be executed by practitioners without the support of collaboration professionals such as facilitators. A critical challenge in Collaboration Engineering concerns how the design activi

  14. Patterns of change in design metaphor: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Stubblefield, W.A.

    1998-04-01

    Design metaphors play an important role in the development of many software projects. However, the influence of metaphors on project functionality, design methodology and the interactions among members of the development team is not well understood. This paper seeks insights into these issues by examining the experiences of a design team in building a system under the influence of a particularly strong design metaphor.

  15. Study of packaging design based on Chinese traditional elements

    Institute of Scientific and Technical Information of China (English)

    崔蓝幻

    2015-01-01

    Summary: Chinese traditional culture of China’s packaging design workers provide material inexhaustible creative ideas. In recent years, most of the fusion of traditional elements in the international and domestic importance of packaging in the design. By analyzing the elements of traditional Chinese and international best packaging design combined with each other, its essence applied to packaging design in the past.

  16. Teaching Ethics for Design for Sustainable Behaviour: A Pilot Study

    Science.gov (United States)

    Lilley, Debra; Lofthouse, Vicky

    2010-01-01

    Design for sustainable behaviour is an emerging activity under the banner of sustainable design which aims to reduce the environmental and social impacts of products by moderating users' interaction with them. The intended outcome of design for sustainable behaviour is to reduce negative environmental and societal impacts. However, designers'…

  17. Self-Authored Graphic Design: A Strategy for Integrative Studies

    Science.gov (United States)

    McCarthy, Steven; De Almeida, Cristina Melibeu

    2002-01-01

    The purpose of this essay is to introduce the concepts of self-authorship in graphic design education as part of an integrative pedagogy. The enhanced potential of harnessing graphic design's dual modalities--the integrative processes inherent in design thinking and doing, and the ability of graphic design to engage other disciplines by giving…

  18. Designer as Ethnographer: A Study of Domestic Cooking and Heating Product Design for Irish Older Adults

    OpenAIRE

    2012-01-01

    In many ways, the design of domestic cooking and heating products reflects the zeitgeist of Irish culture throughout the 20th and into the 21st century. From domesticity to materialism, these products have evolved to meet fundamental human needs within the home. Concurrent with this, the methods and processes designers use to create domestic artefacts have evolved and changed. The emergence of Design Ethnography illustrates an evolution where Design has appropriated an establis...

  19. Optimality criteria for the design of 2-color microarray studies.

    Science.gov (United States)

    Kerr, Kathleen F

    2012-01-13

    We discuss the definition and application of design criteria for evaluating the efficiency of 2-color microarray designs. First, we point out that design optimality criteria are defined differently for the regression and block design settings. This has caused some confusion in the literature and warrants clarification. Linear models for microarray data analysis have equivalent formulations as ANOVA or regression models. However, this equivalence does not extend to design criteria. We discuss optimality criterion, and argue against applying regression-style D-optimality to the microarray design problem. We further disfavor E- and D-optimality (as defined in block design) because they are not attuned to scientific questions of interest.

  20. Variability and impact on design of bioequivalence studies.

    Science.gov (United States)

    Van Peer, Achiel

    2010-03-01

    In 2008, the European Agency for the Evaluation of Medicinal Products released a draft guidance on the investigation of bioequivalence for immediate release dosage forms with systemic action to replace the former guidance of a decade ago. Revisions of the regulatory guidance are based upon many questions over the past years and sometimes continuing scientific discussions on the use of the most suitable statistical analysis methods and study designs, particularly for drugs and drug products with high within-subject variability. Although high within-subject variability is usually associated with a coefficient of variation of 30% or more, new approaches are available in the literature to allow a gradual increase and a levelling off of the bioequivalence limits to some maximum wider values (e.g. 75-133%), dependent on the increase in the within-subject variability. The two-way, cross-over single dose study measuring parent drug is still the design of first choice. A partial replicate design with repeating the reference product and scaling the bioequivalence for the reference variability are proposed for drugs with high within-subject variability. In case of high variability, more regulatory authorities may accept a two-stage or group-sequential bioequivalence design using appropriately adjusted statistical analysis. This review also considers the mechanisms why drugs and drug products may exhibit large variability. The physiological complexity of the gastrointestinal tract and the interaction with the physicochemical properties of drug substances may contribute to the variation in plasma drug concentration-time profiles of drugs and drug products and to variability between and within subjects. A review of submitted bioequivalence studies at the Food and Drug Administration's Office of Generic Drugs over the period 2003-2005 indicated that extensive pre-systemic metabolism of the drug substance was the most important explanation for consistently high variability drugs

  1. The Tehran Eye Study: research design and eye examination protocol

    Directory of Open Access Journals (Sweden)

    Fotouhi Akbar

    2003-07-01

    Full Text Available Abstract Background Visual impairment has a profound impact on society. The majority of visually impaired people live in developing countries, and since most disorders leading to visual impairment are preventable or curable, their control is a priority in these countries. Considering the complicated epidemiology of visual impairment and the wide variety of factors involved, region specific intervention strategies are required for every community. Therefore, providing appropriate data is one of the first steps in these communities, as it is in Iran. The objectives of this study are to describe the prevalence and causes of visual impairment in the population of Tehran city; the prevalence of refractive errors, lens opacity, ocular hypertension, and color blindness in this population, and also the familial aggregation of refractive errors, lens opacity, ocular hypertension, and color blindness within the study sample. Methods Design Through a population-based, cross-sectional study, a total of 5300 Tehran citizens will be selected from 160 clusters using a stratified cluster random sampling strategy. The eligible people will be enumerated through a door-to-door household survey in the selected clusters and will be invited. All participants will be transferred to a clinic for measurements of uncorrected, best corrected and presenting visual acuity; manifest, subjective and cycloplegic refraction; color vision test; Goldmann applanation tonometry; examination of the external eye, anterior segment, media, and fundus; and an interview about demographic characteristics and history of eye diseases, eye trauma, diabetes mellitus, high blood pressure, and ophthalmologic cares. The study design and eye examination protocol are described. Conclusion We expect that findings from the TES will show the status of visual problems and their causes in the community. This study can highlight the people who should be targeted by visual impairment prevention programs.

  2. A study into the design of steerable microphone arrays

    CERN Document Server

    Lai, Chiong Ching; Leung, Yee Hong

    2017-01-01

    The book covers the design formulations for broadband beamformer targeting nearfield and farfield sources. The book content includes background information on the acoustic environment, including propagation medium, the array geometries, signal models and basic beamformer designs. Subsequently it introduces design formulation for nearfield, farfield and mixed nearfield-farfield beamformers and extends the design formulation into electronically steerable beamformers. In addition, a robust formulation is introduced for all the designs mentioned.

  3. [Design and study of carbon fiber tracheal prosthesis].

    Science.gov (United States)

    Qi, L; Liu, D; Han, Z; Wang, F

    1998-12-01

    32 healty adult dogs were selected for this experiment. 10 of them were subjected to the tracheal biomechanics test using indices including the relation between stretcher ratio (lambda) and stress (T), the squeeze stress (delta jy) of medical silk thread on trachea, the side stress (Ts) inducing the tracheal collapse, the functional maximum angle (psi max) of tracheal, and the sever area torsion angle (theta max) of tracheal functional maximum curved. According to the indices measured, two types of tracheal prosthesis were designed, and were made of carbon fiber and silicon. They were the straight tube type tracheal prosthesis and the bifurcate type tracheal prosthesis. The straight tube type tracheal prosthesis was studied with a design of two groups comprising a total of 11 dogs. In the experiment group (n = 6), the outer surface of the tube was not coated with silicon, the average survival period was 379.8 days. In the control group (n = 5), the outer surface of the tube was coated with silicon, the average survival period was 90.4 days. The bifurcate type tracheal prosthesis was studied in 11 dogs, the average survival period was 4.32 days. The main causes of death in the experiment were infection and anastomotic dehiscent.

  4. Parametric study of turbine NGV blade lean and vortex design

    Institute of Scientific and Technical Information of China (English)

    Zhang Shaowen; David G. MacManus; Luo Jianqiao

    2016-01-01

    The effects of blade lean and vortex design on the aerodynamics of a turbine entry nozzle guide vane (NGV) are considered using computational fluid dynamics. The aim of the work is to address some of the uncertainties which have arisen from previous studies where conflicting results have been reported for the effect on the NGV. The configuration was initially based on the energy efficient engine turbine which also served as the validation case for the computational method. A total of 17 NGV configurations were evaluated to study the effects of lean and vortex design on row efficiency and secondary kinetic energy. The distribution of mass flow ratio is introduced as an additional factor in the assessment of blade lean effects. The results show that in the turbine entry NGV, the secondary flow strength is not a dominant factor that determines NGV losses and therefore the changes of loading distribution due to blade lean and the associated loss mecha-nisms should be regarded as a key factor. Radial mass flow redistribution under different NGV lean and twist is demonstrated as an addition key factor influencing row efficiency.

  5. Parametric study of turbine NGV blade lean and vortex design

    Directory of Open Access Journals (Sweden)

    Zhang Shaowen

    2016-02-01

    Full Text Available The effects of blade lean and vortex design on the aerodynamics of a turbine entry nozzle guide vane (NGV are considered using computational fluid dynamics. The aim of the work is to address some of the uncertainties which have arisen from previous studies where conflicting results have been reported for the effect on the NGV. The configuration was initially based on the energy efficient engine turbine which also served as the validation case for the computational method. A total of 17 NGV configurations were evaluated to study the effects of lean and vortex design on row efficiency and secondary kinetic energy. The distribution of mass flow ratio is introduced as an additional factor in the assessment of blade lean effects. The results show that in the turbine entry NGV, the secondary flow strength is not a dominant factor that determines NGV losses and therefore the changes of loading distribution due to blade lean and the associated loss mechanisms should be regarded as a key factor. Radial mass flow redistribution under different NGV lean and twist is demonstrated as an addition key factor influencing row efficiency.

  6. Abrasive blasting agents: designing studies to evaluate relative risk.

    Science.gov (United States)

    Hubbs, Ann; Greskevitch, Mark; Kuempel, Eileen; Suarez, Fernando; Toraason, Mark

    Workers exposed to respirable crystalline silica used in abrasive blasting are at increased risk of developing a debilitating and often fatal fibrotic lung disease called silicosis. The National Institute for Occupational Safety and Health (NIOSH) recommends that silica sand be prohibited as abrasive blasting material and that less hazardous materials be used in blasting operations. However, data are needed on the relative risks associated with exposure to abrasive blasting materials other than silica. NIOSH has completed acute studies in rats (Hubbs et al., 2001; Porter et al., 2002). To provide dose-response data applicable to making recommendation for occupational exposure limits, NIOSH has collaborated with the National Toxicology Program (NTP) to design longer term studies with silica substitutes. For risk assessment purposes, selected doses will include concentrations that are relevant to human exposures. Rat lung burdens achieved should be comparable to those estimated in humans with working lifetime exposures, even if this results in "overloading" doses in rats. To quantify both dose and response, retained particle burdens in the lungs and lung-associated lymph nodes will be measured, as well as biochemical and pathological indices of pulmonary response. This design will facilitate assessment of the pulmonary fibrogenic potential of inhaled abrasive blasting agents at occupationally relevant concentrations.

  7. Effects of study design and trends for EVAR versus OSR

    Directory of Open Access Journals (Sweden)

    Robert Hopkins

    2008-10-01

    Full Text Available Robert Hopkins1, James Bowen1, Kaitryn Campbell1, Gord Blackhouse4, Guy De Rose2,3, Teresa Novick2, Daria O’Reilly1,4, Ron Goeree1,4, Jean-Eric Tarride1,41Programs for the Assessment of Technology in Health (PATH Research Institute, Department of Clinical Epidemiology and Biostatistics; 2Division of Vascular Surgery, Department of Surgery, London Health Sciences Centre, London, Ontario, Canada; 3Division of Vascular Surgery, Department of Surgery, Faculty of Medicine, University of Western Ontario, London, Ontario, Canada; 4Department of Clinical Epidemiology and Biostatistics, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, CanadaPurpose: To investigate if study design factors such as randomization, multi-centre versus single centre evidence, institutional surgical volume, and patient selection affect the outcomes for endovascular repair (EVAR versus open surgical repair (OSR. Finally, we investigate trends over time in EVAR versus OSR outcomes.Methods: Search strategies for comparative studies were performed individually for: OVID’s MEDLINE, EMBASE, CINAHL, HAPI, and Evidence Based Medicine (EBM Reviews (including Cochrane DSR, ACP Journal Club, DARE and CCTR, limited to 1990 and November 2006.Results: Identified literature: 84 comparative studies pertaining to 57,645 patients. These include 4 randomized controlled trials (RCTs, plus 2 RCTs with long-term follow-up. The other 78 comparative studies were nonrandomized with 75 reporting perioperative outcomes, of which 16 were multi-centre, and 59 single-centre studies. Of the single-centre studies 31 were low-volume and 28 were high-volume centres. In addition, 5 studies had all patients anatomically eligible for EVAR, and 8 studies included high-risk patients only. Finally, 25 long term observational studies reported outcomes up to 3 years.Outcomes: Lower perioperative mortality and rates of complications for EVAR versus OSR varied across study designs and patient

  8. Mars Design Reference Architecture 5.0 Study: Executive Summary

    Science.gov (United States)

    Drake, Bret G.

    2008-01-01

    The NASA Mars Design Reference Architecture 5.0 Study seeks to update its long term goals and objective for human exploration missions; flight and surface systems for human missions and supporting infrastructure; operational concept for human and robotic exploration of Mars; key challenges including risk and cost drivers; and, its development schedule options. It additionally seeks to assess strategic linkages between lunar and Mars strategies and develop and understanding of methods for reducing the cost/risk of human Mars missions through investment in research, technology development, and synergy with other exploration plans. Recommendations are made regarding conjunction class (long-stay) missions which are seen as providing the best balance of cost, risk, and performance. Additionally, this study reviews entry, descent, and landing challenges; in-space transportation systems; launch vehicle and Orion assessments; risk and risk mitigation; key driving requirements and challenges; and, lunar linkages.

  9. VHTR engineering design study: intermediate heat exchanger program. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1976-11-01

    The work reported is the result of a follow-on program to earlier Very High Temperature Reactor (VHTR) studies. The primary use of the VHTR is to provide heat for various industrial processes, such as hydrocarbon reforming and coal gasification. For many processes the use of an intermediate heat transfer barrier between the reactor coolant and the process is desirable; for some processes it is mandatory. Various intermediate heat exchanger (IHX) concepts for the VHTR were investigated with respect to safety, cost, and engineering design considerations. The reference processes chosen were steam-hydrocarbon reforming, with emphasis on the chemical heat pipe, and steam gasification of coal. The study investigates the critically important area of heat transfer between the reactor coolant, helium, and the various chemical processes.

  10. Educational Designs Supporting Student Engagement Through Network Project Studies

    DEFF Research Database (Denmark)

    Nielsen, Jørgen Lerche

    2016-01-01

    , developed from the traditions of organizing university studies through student-driven project work and problem-driven learning approaches, which have been developed at the Danish universities of Roskilde and Aalborg as early as from the beginning of the 1970s. Specific educational designs integrating...... digital media are discussed, especially focusing on student engagement and the implications of organizing the pedagogical practice as networked project work. The discussions are based on the author’s experiences during 16 years of teaching and supervising at the Danish Master’s Program of ICT and Learning...... (MIL), where students conduct blended learning study in groups within a networked learning structure. In problem-oriented learning and teaching, teachers act as well as teachers and as supervisors of students’ projects. This challenges the traditional teacher role, and it is crucial for a teacher...

  11. Nuclear-powered Hysat spacecraft: comparative design study

    Energy Technology Data Exchange (ETDEWEB)

    Raab, B.

    1975-08-01

    The study shows that the all-nuclear spacecraft can have a substantial weight advantage over a hybrid (nuclear/solar) or all-solar spacecraft, owing to a further reduction in power requirement, and to the elimination of such equipment as the sensor gimbal and rotating joint assemblies. Because the need for a sun-oriented section is eliminated, the all-nuclear spacecraft can be designed as a monolithic structure, with the sensor and other payload firmly secured in a fixed position on the structure. This enhances attitude stability while minimizing structural weight and eliminating the need for flexible fluid lines. Sensor motion can be produced, varied, and controlled within the limits specified by the study contractors by moving the entire spacecraft in the prescribed pattern. A simple attitude control system using available hardware suffices to meet all requirements.

  12. Platform for dynamic tests: preliminary studies, design and construction

    Directory of Open Access Journals (Sweden)

    J. E. Campuzano

    Full Text Available This paper is about the design and construction of a platform for dynamic tests especially with people jumping, walking, etc. Initially it was tried to find out projects already implemented in platforms and dynamic tests and to study the loads produced by movement of people on slabs and the structural response to these loads. The limits established by different standards have been also studied for these dynamic responses, taking into account the ultimate limit state, as well as the structure in service, since the human body is very sensitive to structural vibrations. Parametric studies were performed considering various configurations of slabs (different spans, thicknesses and conditions of support have been done, looking for a configuration that could have natural frequency close to the frequencies of the human loads. The slab should have dimensions compatible with the available physical space, fundamental frequency below 5 Hz and maximum immediate deflection compatible with the indications of the Brazilian standard NBR6118: 2007. Based on these criteria was chosen a rectangular structure consists of a solid reinforced concrete rectangular slab studded in two opposite edges of steel beams with shear connectors type U. The other two edges are free. The steel beams supporting the slab, in turn, are supported on eight metal profiles (two in each corner of the slab that are supported on two to two short columns of steel profile H. Profiles U in steel are welded to four columns, forming a horizontal frame. Numerical analysis of the dynamic test platform have been performed for free and forced vibration, for obtaining the natural frequencies and corresponding vibration modes, considering the self-weight of the structure and the load that simulates people's weight. After obtaining a structural configuration that fulfilled the stipulated requirements, the design of the slab taking into account the recommendations of the Brazilian standard NBR6118: 2007

  13. The Study on Mental Health at Work: Design and sampling.

    Science.gov (United States)

    Rose, Uwe; Schiel, Stefan; Schröder, Helmut; Kleudgen, Martin; Tophoven, Silke; Rauch, Angela; Freude, Gabriele; Müller, Grit

    2017-08-01

    The Study on Mental Health at Work (S-MGA) generates the first nationwide representative survey enabling the exploration of the relationship between working conditions, mental health and functioning. This paper describes the study design, sampling procedures and data collection, and presents a summary of the sample characteristics. S-MGA is a representative study of German employees aged 31-60 years subject to social security contributions. The sample was drawn from the employment register based on a two-stage cluster sampling procedure. Firstly, 206 municipalities were randomly selected from a pool of 12,227 municipalities in Germany. Secondly, 13,590 addresses were drawn from the selected municipalities for the purpose of conducting 4500 face-to-face interviews. The questionnaire covers psychosocial working and employment conditions, measures of mental health, work ability and functioning. Data from personal interviews were combined with employment histories from register data. Descriptive statistics of socio-demographic characteristics and logistic regressions analyses were used for comparing population, gross sample and respondents. In total, 4511 face-to-face interviews were conducted. A test for sampling bias revealed that individuals in older cohorts participated more often, while individuals with an unknown educational level, residing in major cities or with a non-German ethnic background were slightly underrepresented. There is no indication of major deviations in characteristics between the basic population and the sample of respondents. Hence, S-MGA provides representative data for research on work and health, designed as a cohort study with plans to rerun the survey 5 years after the first assessment.

  14. Design Integration - a theroretical and empirical study of design integration in small and medium sized Danish companies

    DEFF Research Database (Denmark)

    Erichsen, Pia Geisby

    dynamiske modeller i ældre dele af design management litteraturen (som ikke blev identificeret i første litteratur studie a design management). Her blev Dumas & Mintzbergs (1989) forskning identificeret som en relevant model for at få en bedre forståelse af designintegration. Inddragelsen af disse...... fokus i organisationen, manglende nuancer i forståelsen af designs mulige retninger, design blev forbundet med risiko, mangel på tid, og design kunne ikke differentieres fra andre teoretiske discipliner så som marketing. I case studiet indikeres imidlertid også at en drivkraft for at overkomme disse...

  15. Study, simulation and design of a 3D clinostat

    Science.gov (United States)

    Pavone, Valentina; Guarnieri, Vincenzo; Lobascio, Cesare; Soma, Aurelio; Bosso, Nicola; Lamantea, Matteo Maria

    High cost and limited number of physically executable experiments in space have introduced the need for ground simulation systems that enable preparing experiments to be carried out on board, identifying phenomena associated with the altered gravity conditions, and taking advantage of these conditions, as in Biotechnology. Among systems developed to simulate microgravity, especially for life sciences experiments, different types of clinostats were realized. This work deals with mechanical design of a three-dimensional clinostat and simulation of the dynamic behavior of the system by varying the operating parameters. The design and simulation phase was preceded by a careful analysis of the state of art and by the review of the most recent results, in particular from the major investigators of Life Sciences in Space. The mechanical design is quite innovative by adoption of a structure entirely in aluminum, which allows robustness while reducing the overall weight. The transmission system of motion has been optimized by means of brushless DC micro motors, light and compact, which helped to reduce weight, dimensions, power consumption and increase the reliability and durability of the system. The study of the dynamic behavior using SIMPACK, a multibody simulation software, led to results in line with those found in the most important and recent scientific publications. This model was also appropriately configured to represent any desired operating condition, and for eventual system scalability. It would be interesting to generate simulated hypogravity - e.g.: 0.38-g (Mars) or 0.17-g (Moon). This would allow to investigate how terrestrial life forms can grow in other planetary habitats, or to determine the gravity threshold response of different organisms. At the moment, such a system can only be achieved by centrifuges in real microgravity. We are confident that simulation and associated tests with our 3D clinostat can help adjusting the parameters allowing variable g

  16. Spent Nuclear Fuel (SNF) Project Design Basis Capacity Study

    Energy Technology Data Exchange (ETDEWEB)

    CLEVELAND, K.J.

    2000-08-17

    This study of the design basis capacity of process systems was prepared by Fluor Federal Services for the Spent Nuclear Fuel Project. The evaluation uses a summary level model of major process sub-systems to determine the impact of sub-system interactions on the overall time to complete fuel removal operations. The process system model configuration and time cycle estimates developed in the original version of this report have been updated as operating scenario assumptions evolve. The initial document released in Fiscal Year (FY) 1996 varied the number of parallel systems and transport systems over a wide range, estimating a conservative design basis for completing fuel processing in a two year time period. Configurations modeling planned operations were updated in FY 1998 and FY 1999. The FY 1998 Base Case continued to indicate that fuel removal activities at the basins could be completed in slightly over 2 years. Evaluations completed in FY 1999 were based on schedule modifications that delayed the start of KE Basin fuel removal, with respect to the start of KW Basin fuel removal activities, by 12 months. This delay resulted in extending the time to complete all fuel removal activities by 12 months. However, the results indicated that the number of Cold Vacuum Drying (CVD) stations could be reduced from four to three without impacting the projected time to complete fuel removal activities. This update of the design basis capacity evaluation, performed for FY 2000, evaluates a fuel removal scenario that delays the start of KE Basin activities such that staffing peaks are minimized. The number of CVD stations included in all cases for the FY 2000 evaluation is reduced from three to two, since the scenario schedule results in minimal time periods of simultaneous fuel removal from both basins. The FY 2000 evaluation also considers removal of Shippingport fuel from T Plant storage and transfer to the Canister Storage Building for storage.

  17. Preliminary design study of the Tandem Mirror Reactor (TMR)

    Energy Technology Data Exchange (ETDEWEB)

    Moir, R.W.; Barr, W.L.; Carlson, G.A.

    1978-07-15

    This report describes work done in Fiscal Year 1977 by the Fusion Reactor Studies Group of LLL on the conceptual design of a 1000-MW(e) Tandem Mirror Reactor (TMR). The high Q (defined as the ratio of fusion power to injection power) predicted for the TMR (approximately 5) reduces the recirculating power to a nondominant problem and results in an attractive mirror fusion power plant. The fusion plasma of the TMR is contained in the 100-m-long central cell where the magnetic field strength is a modest 2 T. The blanket for neutron energy recovery and tritium breeding is cylindrical and, along with the solenoidal magnet, is divided into 3-m-long modules to facilitate maintenance. The central cell is fueled (but not heated) by the injection of low-energy neutral beams near its ends. Thus, the central cell is simple and of low technology. The end-cell plasmas must be of high density and high energy in order to plug and heat (via the electrons) the central-cell plasma. The present conceptual design uses 1.2-MeV neutral-beam injection for the end plugs and a cryogenic-aluminum, Yin-Yang magnet that produces an incremental field of about 1 T over a field of 16 T produced by a pair of Nb/sub 3/Sn superconducting solenoids. Important design problems remain in both the neutral-beam injector and in the end-plug magnet. Also remaining are important physics questions such as alpha-beam particle transport and end-plug stability. These questions are discussed at length in the report and suggestions for future work are given.

  18. A Study on Conceptual Design of Mechatronic System

    Institute of Scientific and Technical Information of China (English)

    YAO Li-ming; ZOU Ling-lin

    2008-01-01

    The conceptual design of mechatronic systems is addressed under the thrust of concurrent engineering and an enhanced conceptual design methodology describing the early design stage of mechatmnic systems is presented through an example illustration of a pick and place robot.This methodology treats each feasible solution as a solution strategy.In the methodology,Quality Function Deployment (QFD)is used as a baseline for the analysis of the mapping from customers to engineering requirements,Axiomatic Design(AD)is adopted as a guideline to generate feasible,good design solution alternatives,and Theory of Inventive Problem Solving(TRIZ)is applied to deal with domain conflicts in design.

  19. Ultra-Supercritical Pressure CFB Boiler Conceptual Design Study

    Energy Technology Data Exchange (ETDEWEB)

    Zhen Fan; Steve Goidich; Archie Robertson; Song Wu

    2006-06-30

    Electric utility interest in supercritical pressure steam cycles has revived in the United States after waning in the 1980s. Since supercritical cycles yield higher plant efficiencies than subcritical plants along with a proportional reduction in traditional stack gas pollutants and CO{sub 2} release rates, the interest is to pursue even more advanced steam conditions. The advantages of supercritical (SC) and ultra supercritical (USC) pressure steam conditions have been demonstrated in the high gas temperature, high heat flux environment of large pulverized coal-fired (PC) boilers. Interest in circulating fluidized bed (CFB) combustion, as an alternative to PC combustion, has been steadily increasing. Although CFB boilers as large as 300 MWe are now in operation, they are drum type, subcritical pressure units. With their sizes being much smaller than and their combustion temperatures much lower than those of PC boilers (300 MWe versus 1,000 MWe and 1600 F versus 3500 F), a conceptual design study was conducted herein to investigate the technical feasibility and economics of USC CFB boilers. The conceptual study was conducted at 400 MWe and 800 MWe nominal plant sizes with high sulfur Illinois No. 6 coal used as the fuel. The USC CFB plants had higher heating value efficiencies of 40.6 and 41.3 percent respectively and their CFB boilers, which reflect conventional design practices, can be built without the need for an R&D effort. Assuming construction at a generic Ohio River Valley site with union labor, total plant costs in January 2006 dollars were estimated to be $1,551/kW and $1,244/kW with costs of electricity of $52.21/MWhr and $44.08/MWhr, respectively. Based on the above, this study has shown that large USC CFB boilers are feasible and that they can operate with performance and costs that are competitive with comparable USC PC boilers.

  20. Operationalising elaboration theory for simulation instruction design: a Delphi study.

    Science.gov (United States)

    Haji, Faizal A; Khan, Rabia; Regehr, Glenn; Ng, Gary; de Ribaupierre, Sandrine; Dubrowski, Adam

    2015-06-01

    The aim of this study was to assess the feasibility of incorporating the Delphi process within the simplifying conditions method (SCM) described in elaboration theory (ET) to identify conditions impacting the complexity of procedural skills for novice learners. We generated an initial list of conditions impacting the complexity of lumbar puncture (LP) from key informant interviews (n = 5) and a literature review. Eighteen clinician-educators from six different medical specialties were subsequently recruited as expert panellists. Over three Delphi rounds, these panellists rated: (i) their agreement with the inclusion of the simple version of the conditions in a representative ('epitome') training scenario, and (ii) how much the inverse (complex) version increases LP complexity for a novice. Cronbach's α-values were used to assess inter-rater agreement. All panellists completed Rounds 1 and 2 of the survey and 17 completed Round 3. In Round 1, Cronbach's α-values were 0.89 and 0.94 for conditions that simplify and increase LP complexity, respectively; both values increased to 0.98 in Rounds 2 and 3. With the exception of 'high CSF (cerebral spinal fluid) pressure', panellists agreed with the inclusion of all conditions in the simplest (epitome) training scenario. Panellists rated patient movement, spinal anatomy, patient cooperativeness, body habitus, and the presence or absence of an experienced assistant as having the greatest impact on the complexity of LP. This study demonstrated the feasibility of using expert consensus to establish conditions impacting the complexity of procedural skills, and the benefits of incorporating the Delphi method into the SCM. These data can be used to develop and sequence simulation scenarios in a progressively challenging manner. If the theorised learning gains associated with ET are realised, the methods described in this study may be applied to the design of simulation training for other procedural and non-procedural skills

  1. Hybrid vehicle system studies and optimized hydrogen engine design

    Energy Technology Data Exchange (ETDEWEB)

    Smith, J.R.; Aceves, S.

    1995-04-26

    We have done system studies of series hydrogen hybrid automobiles that approach the PNGV design goal of 34 km/liter (80 mpg), for 384 km (240 mi) and 608 km (380 mi) ranges. Our results indicate that such a vehicle appears feasible using an optimized hydrogen engine. We have evaluated the impact of various on-board storage options on fuel economy. Experiments in an available engine at the Sandia CRF demonstrated NO{sub x} emissions of 10 to 20 ppM at an equivalence ratio of 0.4, rising to about 500 ppm at 0.5 equivalence ratio using neat hydrogen. Hybrid simulation studies indicate that exhaust NO{sub x} concentrations must be less than 180 ppM to meet the 0.2 g/mile ULEV or Federal Tier II emissions regulations. LLNL has designed and fabricated a first generation optimized hydrogen engine head for use on an existing Onan engine. This head features 15:1 compression ratio, dual ignition, water cooling, two valves and open quiescent combustion chamber to minimize heat transfer losses. Initial testing shows promise of achieving an indicated efficiency of nearly 50% and emissions of less than 100 ppM NO{sub x}. Hydrocarbons and CO are to be measured, but are expected to be very low since their only source is engine lubricating oil. A successful friction reduction program on the Onan engine should result in a brake thermal efficiency of about 42% compared to today`s gasoline engines of 32%. Based on system studies requirements, the next generation engine will be about 2 liter displacement and is projected to achieve 46% brake thermal efficiency with outputs of 15 kW for cruise and 40 kW for hill climb.

  2. The INTERPHONE study: design, epidemiological methods, and description of the study population

    DEFF Research Database (Denmark)

    Cardis, Elisabeth; Richardson, Lesley; Deltour, Isabelle

    2007-01-01

    . This paper describes the study design and methods and the main characteristics of the study population. INTERPHONE is the largest case-control study to date investigating risks related to mobile phone use and to other potential risk factors for the tumours of interest and includes 2,765 glioma, 2...

  3. Study design, participation and characteristics of The Danish General Suburban Population Study

    DEFF Research Database (Denmark)

    Bergholdt, Helle Kirstine Mørup; Bathum, Lise; Kvetny, Jan

    2013-01-01

    The aim of this article was to describe the study design, participants and baseline characteristics of The Danish General Suburban Population Study (GESUS) and to compare suburban participants with age- and gender-matched urban participants from the Copenhagen General Population Study (CGPS)....

  4. Study design, participation and characteristics of The Danish General Suburban Population Study

    DEFF Research Database (Denmark)

    Bergholdt, Helle Kirstine Mørup; Bathum, Lise; Kvetny, Jan;

    2013-01-01

    The aim of this article was to describe the study design, participants and baseline characteristics of The Danish General Suburban Population Study (GESUS) and to compare suburban participants with age- and gender-matched urban participants from the Copenhagen General Population Study (CGPS)....

  5. Study design, participation and characteristics of the Danish General Suburban Population Study

    DEFF Research Database (Denmark)

    Bergholdt, Helle Kirstine Mørup; Kvetny, Jan; Rasmussen, Dorthe;

    2013-01-01

    The aim of this article was to describe the study design, participants and baseline characteristics of The Danish General Suburban Population Study (GESUS) and to compare suburban participants with age- and gender-matched urban participants from the Copenhagen General Population Study (CGPS)....

  6. Studies on the key parameters in segmental lining design

    Institute of Scientific and Technical Information of China (English)

    Zhenchang Guan; Tao Deng; Gang Wang; Yujing Jiang

    2015-01-01

    The uniform ring model and the shell-spring model for segmental lining design are reviewed in this article. The former is the most promising means to reflect the real behavior of segmental lining, while the latter is the most popular means in practice due to its simplicity. To understand the relationship and the difference between these two models, both of them are applied to the engineering practice of Fuzhou Metro Line I, where the key parameters used in both models are described and compared. The effective ratio of bending rigidity h reflecting the relative stiffness between segmental lining and surrounding ground and the transfer ratio of bending moment x reflecting the relative stiffness between segment and joint, which are two key parameters used in the uniform ring model, are especially emphasized. The reasonable values for these two key parameters are calibrated by comparing the bending moments calculated from both two models. Through case studies, it is concluded that the effective ratio of bending rigidity h increases significantly with good soil properties, increases slightly with increasing overburden, and decreases slightly with increasing water head. Meanwhile, the transfer ratio of bending moment x seems to only relate to the properties of segmental lining itself and has a minor relation with the ground conditions. These results could facilitate the design practice for Fuzhou Metro Line I, and could also provide some references to other projects with respect to similar scenarios.

  7. Comparative Study of Data Warehouse Design Approaches : A Survey

    Directory of Open Access Journals (Sweden)

    Rajni Jindal

    2012-03-01

    Full Text Available The process of developing a data warehouse starts with identifying and gathering requirements, designing the dimensional model followed by testing and maintenance. The design phase is the most important activity in the successful building of a data warehouse. In this paper, we surveyed and evaluated the literature related to the various data warehouse design approaches on the basis of design criteria and propose a generalized object oriented conceptual designframework based on UML that meets all types of user needs.

  8. Communicating Emotion through Haptic Design: A Study Using Physical Keys

    DEFF Research Database (Denmark)

    Kjellerup, Marie Kjær; Larsen, Anne Cathrine; Maier, Anja

    2014-01-01

    This paper explores how designers may communicate with the users of their products through haptic design. More specifically, how tactile properties of materials evoke emotions such as satisfaction, joy, or disgust. A research through design approach has been followed; mood- and material boards an...

  9. Design study of RL10 derivatives. Volume 2: Engine design characteristics. [application of rocket engine to space tug propulsion

    Science.gov (United States)

    Adams, A.

    1973-01-01

    The design characteristics of the RL-10 rocket engine are discussed. The results from critical elements evaluation, baseline engine design, parametric and special study tasks are presented. Critical element evaluation established the feasibility of various engine features such as tank head idle, pumped idle, autogenous tank pressurization, and two-phase pumping. Three baseline engines, derived from the RL-10 were conceptually designed. Parametric life and performance data were generated. Special studies were conducted to establish the impact on the engine design of environment, safety, interchangeability, and maintenance.

  10. Technological issues and experimental design of gene association studies.

    Science.gov (United States)

    Distefano, Johanna K; Taverna, Darin M

    2011-01-01

    Genome-wide association studies (GWAS), in which thousands of single-nucleotide polymorphisms (SNPs) spanning the genome are genotyped in individuals who are phenotypically well characterized, -currently represent the most popular strategy for identifying gene regions associated with common -diseases and related quantitative traits. Improvements in technology and throughput capability, development of powerful statistical tools, and more widespread acceptance of pooling-based genotyping approaches have led to greater utilization of GWAS in human genetics research. However, important considerations for optimal experimental design, including selection of the most appropriate genotyping platform, can enhance the utility of the approach even further. This chapter reviews experimental and technological issues that may affect the success of GWAS findings and proposes strategies for developing the most comprehensive, logical, and cost-effective approaches for genotyping given the population of interest.

  11. Preliminary Design Study for a National Digital Seismograph Network

    Science.gov (United States)

    Peterson, Jon; Hutt, Charles R.

    1981-01-01

    Introduction Recently, the National Research Council published a report by the Panel on National, Regional, and Local Seismograph Networks of the Committee on Seismology in which the principal recommendation was for the establishment of a national digital seismograph network (NDSN). The Panel Report (Bolt, 1980) addresses both the need and the scientific requirements for the new national network. The purpose of this study has been to translate the scientific requirements into an instrumentation concept for the NSDS. There are literally hundreds, perhaps thousands, of seismographs in operation within the United States. Each serves an important purpose, but most have limited objectives in time, in region, or in the types of data that are being recorded. The concept of a national network, funded and operated by the Federal Government, is based on broader objectives that include continuity of time, uniform coverage, standardization of data format and instruments, and widespread use of the data for a variety of research purposes. A national digital seismograph network will be an important data resource for many years to come; hence, its design is likely to be of interest to most seismologists. Seismologists have traditionally been involved in the development and field operation of seismic systems and thus have been familiar with both the potential value and the limitations of the data. However, in recent years of increasing technological sophistication, the development of data sstems has fallen more to system engineers, and this trend is likely to continue. One danger in this is that the engineers may misinterpret scientific objectives or subordinate them to purely technological considerations. Another risk is that the data users may misuse or misinterpret the data because they are not aware of the limitations of the data system. Perhaps the most important purpose of a design study such as this is to stimulate a dialogue between system engineers and potential data users

  12. A Case Study: Foundation Design in Liquefiable Site

    Directory of Open Access Journals (Sweden)

    Tahar Ayadat

    2017-01-01

    Full Text Available The liquefaction is a phenomenon which occurs under seismic solicitation. The passage of a seismic wave (i.e. strong shaking leads, in certain geological formations, to the loss of shearing resistance in saturated sandy materials. This is caused mainly by the increase of the pore water pressure generated by the cyclical deformations. The instantaneous deconsolidation of the soil is reflected by the destruction of the soil mass; making the constructions on such soils unstable. In this geotechnical investigation a case study of foundation design on liquefiable site is described. The geotechnical investigation, carried out at Kent (Ontario, consisted of the construction of a new electrical station on a liquefiable site

  13. Studies on Slurry Design Fundamentals for Advanced CMP Applications

    KAUST Repository

    Basim, G. B.

    2013-06-14

    New developments and device performance requirements in microelectronics industry add to the challenges in chemical mechanical planarization (CMP) process. One of the recently introduced materials is germanium which enables improved performance through better channel mobility in shallow trench isolation (STI) applications. This paper reports on the slurry design alternatives for Ge CMP with surfactant mediation to improve on the silica/germanium selectivity using colloidal silica slurry. In addition to the standard CMP tests to evaluate the material removal rates, atomic force microscopy (AFM) based wear tests were also conducted to evaluate single particle-surface interaction of the polishing system. Furthermore, nature of the surface oxide film of germanium was studied through contact angle measurements and surface roughness tested by AFM. It was observed that the CMP selectivity of the silica/germanium system and defectivity control were possible with a reasonable material removal rate value by using self-assembled structures of cationic surfactants.

  14. Design and properties study of fiber optic glucose biosensor

    Institute of Scientific and Technical Information of China (English)

    Desheng Jiang(姜德生); Er Liu(刘尔); Xin Chen(陈兴); Jun Huang(黄俊)

    2003-01-01

    A new type of fiber optic glucose biosensor based on fluorescence quenching has been designed and itsproperties have been studied. Glucose can be oxidized by oxygen when glucose oxidase are used as thecatalyst, therefore, the concentration of glucose can be measured by detecting the consumption of oxygen.For the detection of oxygen concentration, the ruthenium(Ⅱ) complex, Ru(bpy)3Cl2, were used as thefluorescence indicator and its fluorescence lifetime were detected by lock-in technology. The detectingrange of the sensor is 50 - 500 mg/dl and its response time is 30 seconds, showing that this kind of sensorsis possible to be used in clinical diagnosis and detection.

  15. Blast Valve Design and Related Studies : A Review

    Directory of Open Access Journals (Sweden)

    P. K. Sharma

    2016-04-01

    Full Text Available The protective structures required for performing critical operations are vulnerable to the blast and shock loads of advanced weapons. A blast valve is an important component of such structures for ventilation during normal conditions and for protection from blast/ shock during explosion. In this paper, various aspects of blast valve design and related studies are briefly reviewed. The concept and effects of blast wave, blast impact, numerical modelling and deformation of circular plate (one of the critical components of blast valve have been discussed. The merits and demerits of sensing mechanisms viz. remote and direct sensing are discussed. The leakage of blast pressure during finite closing period of the valve (one of the critical problems and the shock tube as a major experimental facility for testing of blast valves are briefly discussed.

  16. CFRP panel concept design study for the CCAT

    Science.gov (United States)

    Martin, Robert N.; Romeo, Robert C.; Kingsley, Jeffrey S.

    2006-06-01

    Under contract from the Cornell-Caltech Atacama Telescope Project (CCAT), Composite Mirror Applications, Inc. (CMA) has undertaken a feasibility design study for the use of Carbon Fiber Reinforced Plastic (CFRP) panels in forming the primary mirror surface. We review some of the past projects using CFRP panel technology for millimeter and submillimeter wavelength radio astronomy telescopes. Pros and cons of the technology are discussed. A particular panel configuration was proposed and computer modeled with finite element analysis (FEA). The technology of replicated CFRP panels for short wavelength radio astronomical telescopes is mature and cost effective. For shorter wavelengths into the IR and visible, it is becoming a very attractive alternative to traditional, heavy glass or metal technologies.

  17. Scaling studies and conceptual experiment designs for NGNP CFD assessment

    Energy Technology Data Exchange (ETDEWEB)

    D. M. McEligot; G. E. McCreery

    2004-11-01

    The objective of this report is to document scaling studies and conceptual designs for flow and heat transfer experiments intended to assess CFD codes and their turbulence models proposed for application to prismatic NGNP concepts. The general approach of the project is to develop new benchmark experiments for assessment in parallel with CFD and coupled CFD/systems code calculations for the same geometry. Two aspects of the complex flow in an NGNP are being addressed: (1) flow and thermal mixing in the lower plenum ("hot streaking" issue) and (2) turbulence and resulting temperature distributions in reactor cooling channels ("hot channel" issue). Current prismatic NGNP concepts are being examined to identify their proposed flow conditions and geometries over the range from normal operation to decay heat removal in a pressurized cooldown. Approximate analyses have been applied to determine key non-dimensional parameters and their magnitudes over this operating range. For normal operation, the flow in the coolant channels can be considered to be dominant turbulent forced convection with slight transverse property variation. In a pressurized cooldown (LOFA) simulation, the flow quickly becomes laminar with some possible buoyancy influences. The flow in the lower plenum can locally be considered to be a situation of multiple hot jets into a confined crossflow -- with obstructions. Flow is expected to be turbulent with momentumdominated turbulent jets entering; buoyancy influences are estimated to be negligible in normal full power operation. Experiments are needed for the combined features of the lower plenum flows. Missing from the typical jet experiments available are interactions with nearby circular posts and with vertical posts in the vicinity of vertical walls - with near stagnant surroundings at one extreme and significant crossflow at the other. Two types of heat transfer experiments are being considered. One addresses the "hot channel" problem, if necessary

  18. Design and biomechanical study of a modified pedicle screw

    Institute of Scientific and Technical Information of China (English)

    LIU Tao; ZHENG Wen-jie; LI Chang-qing; LIU Guo-dong; ZHOU Yue

    2010-01-01

    Objective: In pedicle screw fixation,the heads of monoaxial screws need to be directed in the same straight line to accommodate the rod placement by backing out during operation, which decreases the insertional torque and internal fixation strength. While polyaxial screws facilitate the assembly of the connecting rod, but its ball-in-cup locking mechanism reduces the static compressive bending yield strength as compared with monoaxial screws. Our study aimed to assess the mechanical performance of a modified pedicle screw.Methods: In this study, the tail of the screw body of the modified pedicle screw was designed to be a cylindershaped structure that well matched the inner wall of the screw head and the screw head only rotated around the cyclinder. Monoaxial screws, modified screws and polyaxial screws were respectively assembled into 3 groups ofvertebrectomy models simulated by ultra high molecular weight polyethylene (UHMWPE) blocks. This model was developed according to a standard for destructive mechanical testing published by the American Society for Testing Materials (ASTM F1717-04). Each screw design had 6 subgroups, including 3 for static tension, load compression and torsion tests, and the rest for dynamic compression tests. In dynamic tests, the cyclic loads were 25%, 50%, and 75% of the compressive bending ultimate loads respectively.Yield load, yield ultimate load, yield stiffness, torsional stiffness, cycles to failure and modes of failure for the 3 types of screws were recorded. The results of modified screws were compared with those ofmonoaxial and polyaxial screws.Results: In static tests, results of bending stiffness,yield load, yield torque and torsional stiffness indicated no significant differences between the modified and monoaxial screws (P>0.05), but both differed significantly from those ofpolyaxial screws (P<0.05). In dynamic compression tests,both modified and monoaxial screws showed failures that occurred at the insertion point of screw

  19. A case study of collaborative facilities in engineering design

    Energy Technology Data Exchange (ETDEWEB)

    Monroe, Laura M [Los Alamos National Laboratory; Pugmire, David [ORNL

    2008-01-01

    In this paper we describe the use of visualization tools and facilities in the collaborative design of a replacement weapons system, the Reliable Replacement Warhead (RRW). We used not only standard collaboration methods but also a range of visualization software and facilities to bring together domain specialists from laboratories across the country to collaborate on the design and integrate this disparate input early in the design. This was the first time in U.S. weapons history that a weapon had been designed in this collaborative manner. Benefits included projected cost savings, design improvements and increased understanding across the project.

  20. A Study on Ethnic Artistic Design and Branding Strategy

    Institute of Scientific and Technical Information of China (English)

    ZHUANG Qiao

    2014-01-01

    Ethnic Artistic Design refers to a kind of artistic designing which takes the ethnic minorities’ cultural symbols and cultural connota-tion as its basic material , and which reflects the lo-cal conditions and customs and characteristics of the ethnic minorities.In a strict sense, any coun-try’ s artistic design belongs to “national/ethnic artistic designing”.However, in this article, it specifically refers to the artistic design which takes the cultural symbols of the ethnic minorities of Chi-na as its source , so as to distinguish it from other more general artistic design .

  1. Study of Piezoresistive Micro Electro-Mechanical Accelerometer Design Platform

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    According to the inland micro electro-mechanical system (MEMS) process technique level, a design platform of piezoresistive micro electro-mechanical accelerometer is given. This platform is much more adaptable to the inland designer compared with the current MEMS CAD software. The design flow is presented in detail, and the key techique in the platform is analyzed amply. The structure design methodology is exemplified in the design of a piezoresistive accelerometer, and the accelerometer is the optimized structure for the given performance requirements. The accelerometer is now being manufactured.

  2. Designing with 3D Printed Textiles: A case study of Material Driven Design

    NARCIS (Netherlands)

    Lussenburg, K.; Van der Velden, N.M.; Doubrovski, E.L.; Geraedts, J.M.P.; Karana, E.

    2014-01-01

    This paper describes the findings and results of a design project with the goal to design a wearable garment using 3D Printed textiles, which not only has functional or environmental superiorities, but also experiential ones. The approach that was adopted for this project is a recently developed met

  3. Designing Evaluations: A Study Examining Preferred Evaluation Designs of Educational Evaluators

    Science.gov (United States)

    Azzam, Tarek; Szanyi, Michael

    2011-01-01

    A sample of educational evaluators was asked to design an outcomes-focused evaluation of a school program that aims to improve the academic achievement and self-esteem of students. Evaluators provided detailed descriptions of their evaluation design and methodology in their responses. These descriptions were coded and analyzed to determine the…

  4. “Psychosomatic consultation in the workplace” – a new model of care at the interface of company-supported mental health care and consultation-liaison psychosomatics: design of a mixed methods implementation study

    Directory of Open Access Journals (Sweden)

    Rothermund Eva

    2012-09-01

    Full Text Available Abstract Background Mental health issues are gaining in importance in society and the economic system. At the same time, the accessibility and stigmatisation of the mental health care system in Germany can obstruct help-seeking behavior and delay early psychotherapeutic interventions. Therefore, new models of care are being established at the interface of company-supported health promotion and conventional health insurance sponsored outpatient care for people developing mental illnesses. Two large industrial companies, in cooperation with two psychosomatic clinics, have recently established a model of “psychosomatic consultation in the workplace“. This new model of care offers the opportunity for a first psychotherapeutic door to door consultation with occupational medicine within the industrial workplace. The main empirical goals of this study are: 1 Describing the differences between patients who use this new diagnostic and therapeutic offer within the industrial workplace vs. patients who visit a conventional regional outpatient clinic, especially in regard to symptom duration and severity, work ability, and demographic characteristics, and 2 A first evaluation of how patients may benefit more from this new model of care compared to those first seen by standard outpatient care. In the qualitative part of the study, occupational physicians, psychosomatic therapists, involved personnel and select employees of the involved companies will be asked to comment on their experiences with this new approach. Methods/Design The implementation study will take place in Ulm and in Stuttgart, with each site looking at one regional conventional psychosomatic outpatient clinic and one psychosomatic consultation offer within the workplace. 70 consecutive patients in each setting will be recruited (overall n = 280. For the cross-sectional study and pre-post comparison we will use established and validated survey instruments (PHQ, SF-12, WAI, MBI, IS as

  5. Nai Kun wind farm environmental impact assessment study design

    Energy Technology Data Exchange (ETDEWEB)

    Wilkins, S.; Shum, M.; Embley, E. [Pottinger Gaherty Environmental Consultants Ltd., Vancouver, BC (Canada)

    2002-05-01

    Uniterre Resources Ltd., ABB New Ventures and ABB Inc. propose the Nai Kun Wind Farm project, and the firm Pottinger Gaherty Environmental Consultants LTD. (PGL) was commissioned to conduct an environmental impact assessment for the project. A description of the studies considered as a requirement for the environmental impacts assessment of the project is included in this draft report. Before proceeding with the detailed studies, it was decided to present this draft report to the stakeholders and regulatory authorities to obtain feedback and a review. Nowadays in electricity markets, wind energy is becoming a differentiated and highly valued product. The Nai Kun Wind Farm project, as proposed, would entail the development, construction and operation of a 700 megawatt (MW) wind generation facility located off the northeast coast of Graham Island (Haida Gwaii) in Hecate Strait in British Columbia. It is expected that the project will generate greenhouse gas emission reduction credits. The information about the site and the project, as was known on May 24, 2002, was used for the preparation of this draft report. The present document includes an introduction in Chapter 1, followed by background information in Chapter 2. The Environmental impact assessment framework was reviewed in Chapter 3, and the public consultation plan was described in Chapter 4. The environmental impact assessment designs are discussed in Chapter 5 and a schedule for environmental studies provided in Chapter 6. The next steps are detailed in Chapter 7 of the document. 10 refs., tabs., 1 fig.

  6. GIS-based landscape design research: Stourhead landscape garden as a case study

    NARCIS (Netherlands)

    Nijhuis, S.

    2015-01-01

    Landscape design research is important for cultivating spatial intelligence in landscape architecture. This study explores GIS (geographic information systems) as a tool for landscape design research – investigating landscape designs to understand them as architectonic compositions and to acquire

  7. Design

    DEFF Research Database (Denmark)

    Volf, Mette

    Design - proces & metode iBog®  er enestående i sit fokus på afmystificering og operationalisering af designprocessens flygtige og komplekse karakter. Udgivelsen går bag om designerens daglige arbejde og giver et indblik i den kreative skabelsesproces, som designeren er en del af. Udover et bredt...... indblik i designerens arbejdsmetoder og designparametre giver Design - proces & metode en række eksempler fra anerkendte designvirksomheder, der gør det muligt at komme helt tæt på designerens virkelighed....

  8. Magnetic field effects on humans: epidemiological study design

    Energy Technology Data Exchange (ETDEWEB)

    Budinger, T.F.; Wong, P.; Yen, C.K.

    1978-10-01

    This report presents details of the study design and methods for a retrospective epidemiological study on the health effects, if any, of stationary and alternating magnetic fields produced by man-made devices such as cyclotrons, controlled thermonuclear reactors (CTR), high voltage-high current transmission lines, magnetohydrodynamic devices (MHD), energy storage systems, and isotope separation facilities. The magnetic fields to which the workers can be exposed are as high as 10,000 gauss and the anticipated increase in magnetic fields associated with the environment and transmission lines near these devices is a few times the natural earth magnetic field. Thus the objectives include acquisition of low exposure data which can be used to evaluate any risks to the population incidentally exposed to environmental increases in magnetic fields, as well as an acquisition of high exposure data to be used in determining allowable exposure standards for the technical personnel working at CTR and MHD facilities. From the present status of knowledge on biological effects of magnetic fields, it is not possible to extrapolate or rationally conclude maximum permissible exposure levels for magnetic device workers and the population at large. There are no known previous studies of the effects of long-term exposure to magnetic fields involving large samples and matched controls. Thus this human epidemiological study was commenced in 1977 in parallel with experimental studies on biological and medical effects of magnetic fields being conducted by Dr. T. Tenforde and co-workers at LBL, by investigators at Battelle Northwest, and smaller projects at a number of laboratories around the world. The data base for the exposed population is comprised of approximately 1,000 cyclotron and bubble chamber workers.

  9. Linac Coherent Light Source (LCLS) Design Study Report

    Energy Technology Data Exchange (ETDEWEB)

    Cornacchia, Massimo

    1998-12-04

    The Stanford Linear Accelerator Center, in collaboration with Los Alamos National Laboratory, Lawrence Livermore National Laboratory, and the University of California at Los Angeles, is proposing to build a Free-Electron-Laser (FEL) R and D facility operating in the wavelength range 1.5-15 {angstrom}. This FEL, called the ''Linac Coherent Light Source'' (LCLS), utilizes the SLAC linac and produces sub-picosecond pulses of short wavelength x-rays with very high peak brightness and full transverse coherence. Starting in FY 1998, the first two-thirds of the SLAC linac will be used for injection into the B factory. This leaves the last one-third free for acceleration to 15 GeV. The LCLS takes advantage of this opportunity, opening the way for the next generation of synchrotron light sources with largely proven technology and cost effective methods. This proposal is consistent with the recommendations of the Report of the Basic Energy Sciences Advisory Committee (Synchrotron Radiation Light Source Working Group, October 18-19, 1997). The report recognizes that ''fourth-generation x-ray sources...will in all likelihood be based on the free electron laser concepts. If successful, this technology could yield improvements in brightness by many orders of magnitude.'' This Design Study, the authors believe, confirms the feasibility of constructing an x-ray FEL based on the SLAC linac. Although this design is based on a consistent and feasible set of parameters, some components require more research and development to guarantee the performance. Given appropriate funding, this R and D phase can be completed in 2 years.

  10. Astronomy sortie missions definition study. Volume 3, book 1: Design analysis and trade studies

    Science.gov (United States)

    1972-01-01

    A study to define the astronomy sortie missions was conducted. The design analyses and tradeoff studies conducted for candidate concepts are presented. The subjects discussed are: (1) system and subsystem requirements, (2) space shuttle interfaces, (3) infrared telescope development, and (4) experiments to be conducted during the mission.

  11. AVID - A design system for technology studies of advanced transportation concepts. [Aerospace Vehicle Interactive Design

    Science.gov (United States)

    Wilhite, A. W.; Rehder, J. J.

    1979-01-01

    The basic AVID (Aerospace Vehicle Interactive Design) is a general system for conceptual and preliminary design currently being applied to a broad range of future space transportation and spacecraft vehicle concepts. AVID hardware includes a minicomputer allowing rapid designer interaction. AVID software includes (1) an executive program and communication data base which provide the automated capability to couple individual programs, either individually in an interactive mode or chained together in an automatic sequence mode; and (2) the individual technology and utility programs which provide analysis capability in areas such as graphics, aerodynamics, propulsion, flight performance, weights, sizing, and costs.

  12. Design

    Science.gov (United States)

    Buchanan, Richard; Cross, Nigel; Durling, David; Nelson, Harold; Owen, Charles; Valtonen, Anna; Boling, Elizabeth; Gibbons, Andrew; Visscher-Voerman, Irene

    2013-01-01

    Scholars representing the field of design were asked to identify what they considered to be the most exciting and imaginative work currently being done in their field, as well as how that work might change our understanding. The scholars included Richard Buchanan, Nigel Cross, David Durling, Harold Nelson, Charles Owen, and Anna Valtonen. Scholars…

  13. Design

    Science.gov (United States)

    Buchanan, Richard; Cross, Nigel; Durling, David; Nelson, Harold; Owen, Charles; Valtonen, Anna; Boling, Elizabeth; Gibbons, Andrew; Visscher-Voerman, Irene

    2013-01-01

    Scholars representing the field of design were asked to identify what they considered to be the most exciting and imaginative work currently being done in their field, as well as how that work might change our understanding. The scholars included Richard Buchanan, Nigel Cross, David Durling, Harold Nelson, Charles Owen, and Anna Valtonen. Scholars…

  14. The Oxford Conception Study design and recruitment experience.

    Science.gov (United States)

    Pyper, Cecilia; Bromhall, Lise; Dummett, Sarah; Altman, Douglas G; Brownbill, Pat; Murphy, Michael

    2006-11-01

    The Oxford Conception Study is a randomised controlled trial that aims to determine whether or not information about potential fertility from a device that monitors urinary hormones will increase the conception rate in women wishing to conceive. Three modified versions of a fertility monitor have been developed for the study. The monitor measures the levels of urinary oestrone-3-glucuronide (E3G) and luteinising hormone (LH), and the display indicates high or low fertility. The monitor requests all women to test their urine from day 6 to day 25 of the menstrual cycle inclusive. One-third of women are randomised to receive information from the fertility monitor about the early fertile time (from the first rise in E3G until the LH surge is detected), one-third receive information about the late fertile time (the onset of the LH surge and the following 2 days), and a third do not receive any information (control group). All the women are followed up for 6 months or until they are pregnant. A total of 1453 women have been recruited into the study, reaching the study recruitment goal for 80% power to detect a 10% difference in three-cycle pregnancy rate between the Late Fertile Time group (50%) and the Control group (40%), allowing for a 15% non-pregnancy drop-out rate. Follow-up of the women is currently ongoing. The primary analysis will compare the cumulative three-cycle pregnancy rate between each of the study arms. Time-specific conception probabilities will be estimated from coitus information recorded in 12-h intervals. The data from this study will also allow many additional questions to be addressed, including changes in intercourse patterns with feedback about the fertile days and other questions in relation to menstrual cycle function, sexual intercourse, stress, exposures to tobacco products, alcohol, caffeine and medications, fertility and pregnancy outcomes. In addition to presenting the study design, we review the recruitment experience for the Oxford

  15. Flexible missile autopilot design studies with PC-MATLAB/386

    Science.gov (United States)

    Ruth, Michael J.

    1989-01-01

    Development of a responsive, high-bandwidth missile autopilot for airframes which have structural modes of unusually low frequency presents a challenging design task. Such systems are viable candidates for modern, state-space control design methods. The PC-MATLAB interactive software package provides an environment well-suited to the development of candidate linear control laws for flexible missile autopilots. The strengths of MATLAB include: (1) exceptionally high speed (MATLAB's version for 80386-based PC's offers benchmarks approaching minicomputer and mainframe performance); (2) ability to handle large design models of several hundred degrees of freedom, if necessary; and (3) broad extensibility through user-defined functions. To characterize MATLAB capabilities, a simplified design example is presented. This involves interactive definition of an observer-based state-space compensator for a flexible missile autopilot design task. MATLAB capabilities and limitations, in the context of this design task, are then summarized.

  16. An Entertainment-Education Study of Stereotypes and Prejudice against Fat Women: An Evaluation of "Fat Pig"

    Science.gov (United States)

    Gesser-Edelsburg, Anat; Endevelt, Ronit

    2011-01-01

    Objective: To evaluate the impact of "Fat Pig" on the attitudes of high school students towards fat women and investigate the perspective of dietitians as health professionals on the messages in "Fat Pig." Design: Performance analysis, pre-post analysis of students' responses to self-administrated pre-constructed…

  17. An Entertainment-Education Study of Stereotypes and Prejudice against Fat Women: An Evaluation of "Fat Pig"

    Science.gov (United States)

    Gesser-Edelsburg, Anat; Endevelt, Ronit

    2011-01-01

    Objective: To evaluate the impact of "Fat Pig" on the attitudes of high school students towards fat women and investigate the perspective of dietitians as health professionals on the messages in "Fat Pig." Design: Performance analysis, pre-post analysis of students' responses to self-administrated pre-constructed questionnaires, students' focus…

  18. Mechanical Design and Fabrication Studies for SPL Superconducting RF Cavities

    CERN Document Server

    Atieh, S; Aviles Santillana, I; Capatina, O; Renaglia, T; Tardy, T; Valverde Alonso, N; Weingarten, W

    2011-01-01

    CERN’s R&D programme on the Superconducting Proton Linac’s (SPL) superconducting radio frequency (SRF) elliptical cavities made from niobium sheets explores new mechanical design and consequently new fabrication methods, where several opportunities for improved optimization were identified. A stainless steel helium vessel is under design rather than a titanium helium vessel using an integrated brazed transition between Nb and the SS helium vessel. Different design and fabrication aspects were proposed and the results are discussed hereafter.

  19. Use of charging control guidelines for geosynchronous satellite design studies

    Science.gov (United States)

    Steves, N. J.

    1980-01-01

    Several of the principle guidelines from the Spacecraft Charging Design Guidelines Handbook are presented with illustrative examples. Use of the geomagnetic substorm specification to qualify satellite designs, the evaluation of satellite designs by using analytical modelling techniques, the use of selected materials and coatings to minimize charging, the tying of all conducting elements to a common ground, and the use of electrical filtering to protect circuits from discharge induced upsets are discussed. Discharge criteria and SCATHA data are excluded.

  20. Novel study designs to investigate the placebo response

    OpenAIRE

    Klosterhalfen Sibylle; Enck Paul; Zipfel Stephan

    2011-01-01

    Abstract Background Investigating the size and mechanisms of the placebo response in clinical trials have relied on experimental procedures that simulate the double-blind randomized placebo-controlled design. However, as the conventional design is thought to elucidate drug rather than placebo actions, different methodological procedures are needed for the placebo response. Methods We reviewed the respective literature for trials designs that may be used to elucidate the size of the placebo re...

  1. A case study of collaborative facilities use in engineering design

    Energy Technology Data Exchange (ETDEWEB)

    Monroe, Laura M [Los Alamos National Laboratory

    2009-01-01

    In this paper we describe the use of visualization tools and facilities in the collaborative design of a replacement weapons system, the Reliable Replacement Warhead. We used not only standard collaboration methods but also a range of visualization software and facilities to bring together domain specialists from laboratories across the country to collaborate on the design and integrate this disparate input early in the design.

  2. Managing multi-architect collaborative design: case study of design competition for Ground Zero in New York

    NARCIS (Netherlands)

    Sebastian, R.

    2006-01-01

    This paper presents a part of the PhD research by the author that responds to the need of an innovative approach to manage collaborative design in the conceptual design phase of a multi-architect building project. The research studied recent multi-architect building projects in the Netherlands, name

  3. New Perspective on Visual Communication Design Education: An Empirical Study of Applying Narrative Theory to Graphic Design Courses

    Science.gov (United States)

    Yang, Chao-Ming; Hsu, Tzu-Fan

    2017-01-01

    Visual communication design (VCD) is a form of nonverbal communication. The application of relevant linguistic or semiotic theories to VCD education renders graphic design an innovative and scientific discipline. In this study, actual teaching activities were examined to verify the feasibility of applying narrative theory to graphic design…

  4. QRAC-the-Code: a comprehension monitoring strategy for middle school social studies textbooks.

    Science.gov (United States)

    Berkeley, Sheri; Riccomini, Paul J

    2013-01-01

    Requirements for reading and ascertaining information from text increase as students advance through the educational system, especially in content-rich classes; hence, monitoring comprehension is especially important. However, this is a particularly challenging skill for many students who struggle with reading comprehension, including students with learning disabilities. A randomized pre-post experimental design was employed to investigate the effectiveness of a comprehension monitoring strategy (QRAC-the-Code) for improving the reading comprehension of 323 students in grades 6 and 7 in inclusive social studies classes. Findings indicated that both general education students and students with learning disabilities who were taught a simple comprehension monitoring strategy improved their comprehension of textbook content compared to students who read independently and noted important points. In addition, students in the comprehension monitoring condition reported using more reading strategies after the intervention. Implications for research and practice are discussed.

  5. Cognitive effects of mindfulness training: Results of a pilot study based on a theory driven approach

    Directory of Open Access Journals (Sweden)

    Lena Wimmer

    2016-07-01

    Full Text Available The present paper reports a pilot study which tested cognitive effects of mindfulness practice in a theory-driven approach. Thirty-four fifth graders received either a mindfulness training which was based on the mindfulness-based stress reduction approach (experimental group, a concentration training (active control group or no treatment (passive control group. Based on the operational definition of mindfulness by Bishop et al. (2004, effects on sustained attention, cognitive flexibility, cognitive inhibition and data-driven as opposed to schema-based information processing were predicted. These abilities were assessed in a pre-post design by means of a vigilance test, a reversible figures test, the Wisconsin Card Sorting Test, a Stroop test, a visual search task, and a recognition task of prototypical faces. Results suggest that the mindfulness training specifically improved cognitive inhibition and data-driven information processing.

  6. A robotic wheelchair trainer: design overview and a feasibility study

    Science.gov (United States)

    2010-01-01

    Background Experiencing independent mobility is important for children with a severe movement disability, but learning to drive a powered wheelchair can be labor intensive, requiring hand-over-hand assistance from a skilled therapist. Methods To improve accessibility to training, we developed a robotic wheelchair trainer that steers itself along a course marked by a line on the floor using computer vision, haptically guiding the driver's hand in appropriate steering motions using a force feedback joystick, as the driver tries to catch a mobile robot in a game of "robot tag". This paper provides a detailed design description of the computer vision and control system. In addition, we present data from a pilot study in which we used the chair to teach children without motor impairment aged 4-9 (n = 22) to drive the wheelchair in a single training session, in order to verify that the wheelchair could enable learning by the non-impaired motor system, and to establish normative values of learning rates. Results and Discussion Training with haptic guidance from the robotic wheelchair trainer improved the steering ability of children without motor impairment significantly more than training without guidance. We also report the results of a case study with one 8-year-old child with a severe motor impairment due to cerebral palsy, who replicated the single-session training protocol that the non-disabled children participated in. This child also improved steering ability after training with guidance from the joystick by an amount even greater than the children without motor impairment. Conclusions The system not only provided a safe, fun context for automating driver's training, but also enhanced motor learning by the non-impaired motor system, presumably by demonstrating through intuitive movement and force of the joystick itself exemplary control to follow the course. The case study indicates that a child with a motor system impaired by CP can also gain a short-term benefit

  7. A robotic wheelchair trainer: design overview and a feasibility study

    Directory of Open Access Journals (Sweden)

    Marchal-Crespo Laura

    2010-08-01

    Full Text Available Abstract Background Experiencing independent mobility is important for children with a severe movement disability, but learning to drive a powered wheelchair can be labor intensive, requiring hand-over-hand assistance from a skilled therapist. Methods To improve accessibility to training, we developed a robotic wheelchair trainer that steers itself along a course marked by a line on the floor using computer vision, haptically guiding the driver's hand in appropriate steering motions using a force feedback joystick, as the driver tries to catch a mobile robot in a game of "robot tag". This paper provides a detailed design description of the computer vision and control system. In addition, we present data from a pilot study in which we used the chair to teach children without motor impairment aged 4-9 (n = 22 to drive the wheelchair in a single training session, in order to verify that the wheelchair could enable learning by the non-impaired motor system, and to establish normative values of learning rates. Results and Discussion Training with haptic guidance from the robotic wheelchair trainer improved the steering ability of children without motor impairment significantly more than training without guidance. We also report the results of a case study with one 8-year-old child with a severe motor impairment due to cerebral palsy, who replicated the single-session training protocol that the non-disabled children participated in. This child also improved steering ability after training with guidance from the joystick by an amount even greater than the children without motor impairment. Conclusions The system not only provided a safe, fun context for automating driver's training, but also enhanced motor learning by the non-impaired motor system, presumably by demonstrating through intuitive movement and force of the joystick itself exemplary control to follow the course. The case study indicates that a child with a motor system impaired by CP can

  8. The use of Animal-Assisted Therapy in adolescents with acute mental disorders: A randomized controlled study.

    Science.gov (United States)

    Stefanini, M C; Martino, A; Allori, P; Galeotti, F; Tani, F

    2015-02-01

    The aim of this study was to compare the effects of Animal-Assisted Therapy (AAT) with a standard treatment protocol in children and adolescents admitted to the psychiatry hospital for acute mental disorders. We used a methodology involving high quality standards for AAT research. A pre-post experimental design with a randomized controlled trial (RCT) in 34 hospitalized patients (17 treatment, 17 control) was carried out. The study focused on improvement in clinical status including, global functioning measured by the Children Global Assessment Scale (C GAS), format of care and ordinary school attendance measured by a rating scale. Our results indicate a statistically significant improvement in global functioning, reduction in format of care and increased ordinary school attendance in the treatment group, but not in the control group. Our results verify that AAT can have significant positive effects on therapeutic progress and the recovery process. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. A Case Study on the Design of Learning Interfaces

    Science.gov (United States)

    Perry, Gabriela Trindade; Schnaid, Fernando

    2012-01-01

    The design of educational software interfaces is a complex task, given its high domain dependency and multidisciplinary nature. It requires that teachers' knowledge and pedagogical beliefs be incorporated into the interface, posing a challenge to both teachers and designers, as they have to act as partners from the earliest phases of the process,…

  10. How University Teachers Design Assessments: A Cross-Disciplinary Study

    Science.gov (United States)

    Bearman, Margaret; Dawson, Phillip; Bennett, Sue; Hall, Matt; Molloy, Elizabeth; Boud, David; Joughin, Gordon

    2017-01-01

    There are dissonances between educators' aspirations for assessment design and actual assessment implementation in higher education. Understanding how assessment is designed "on the ground" can assist in resolving this tension. Thirty-three Australian university educators from a mix of disciplines and institutions were interviewed. A…

  11. Alexandria Digital Library: User Evaluation Studies and System Design.

    Science.gov (United States)

    Hill, Linda L.; Carver, Larry; Larsgaard, Mary; Dolin, Ron; Smith, Terence R.; Frew, James; Rae, Mary-Anna

    2000-01-01

    Describes the Alexandria Digital Library, a geolibrary that focuses on geographical locations. Topics include the evolution of the system and interface design; design goals; user communities, including earth scientists, information specialists, and educators; user evaluation methodologies and findings; and future possibilities. (LRW)

  12. Understanding the Academic Environments: From Field Study to Design

    NARCIS (Netherlands)

    Vyas, Dhaval; de Groot, Spencer; van der Veer, Gerrit C.; Rizzo, Antonio; Grote, Gudela; Wong, William

    2006-01-01

    Ethnographic methods have been widely used for requirements elicitation purposes in systems design, especially when the focus is on understanding users’ social, cultural and political contexts. Designing an on-line search engine for peer-reviewed papers could be a challenge considering the diversity

  13. The Elements and Principles of Design: A Baseline Study

    Science.gov (United States)

    Adams, Erin

    2013-01-01

    Critical to the discipline, both professionally and academically, are the fundamentals of interior design. These fundamentals include the elements and principles of interior design: the commonly accepted tools and vocabulary used to create and communicate successful interior environments. Research indicates a lack of consistency in both the…

  14. Designing New Supply Chain Networks: Tomato and Mango Case Studies

    NARCIS (Netherlands)

    Vorst, van der J.G.A.J.; Schouten, R.E.; Luning, P.A.; Kooten, van O.

    2014-01-01

    Consumers expect product availability as well as product quality and safety in retail outlets. When designing or re-designing fruit and vegetables supply chain networks one has to take these demands into consideration next to traditional efficiency and responsiveness requirements. In food science li

  15. Study on design pressure of in-service welding pipes

    Institute of Scientific and Technical Information of China (English)

    XUE Xiaolong; ZHU Jiagui; SANG Zhifu

    2006-01-01

    A method of predicting design pressure and burn-through of in-service welding pipes was established. Temperature distributions of in-service welding under variable parameters were simulated by FEM. The effect of flowing of internal media was regarded as forced convection. Based on the numerical results, design pressure of the pipe can be obtained and burn-through can be predicted. It can be concluded that the design pressure decreases with the increasing of heat input. RSF and design pressure of the pipe increase with the increasing of flow rate. There is a range in which the increase changes greatly. For in-service welding, the range should be considered adequately to determine operating condition optimally. RSF increases with the increasing of pipe wall thickness. While the thickness increases to an extent, RSF shows little increase. According to the curves of design pressure versus different parameters, safe working pressure can be achieved.

  16. High-$\\gamma$ Beta Beams within the LAGUNA design study

    CERN Document Server

    Orme, Christopher

    2010-01-01

    Within the LAGUNA design study, seven candidate sites are being assessed for their feasibility to host a next-generation, very large neutrino observatory. Such a detector will be expected to feature within a future European accelerator neutrino programme (Superbeam or Beta Beam), and hence the distance from CERN is of critical importance. In this article, the focus is a $^{18}$Ne and $^{6}$He Beta Beam sourced at CERN and directed towards a 50 kton Liquid Argon detector located at the LAGUNA sites: Slanic (L=1570 km) and Pyh\\"{a}salmi (L=2300 km). To improve sensitivity to the neutrino mass ordering, these baselines are then combined with a concurrent run with the same flux directed towards a large Water \\v{C}erenkov detector located at Canfranc (L=650 km). This degeneracy breaking combination is shown to provide comparable physics reach to the conservative Magic Baseline Beta Beam proposals. For $^{18}$Ne ions boosted to $\\gamma=570$ and $^{6}$He ions boosted to $\\gamma=350$, the correct mass ordering can be...

  17. Design and property study of micro-slot optics

    Science.gov (United States)

    Wang, Yuting; Yi, Futing; Zhang, Tianchong; Liu, Jing; Wang, Bo; Zhou, Yue

    2017-03-01

    LIGA (Lithographie Galvanoformung Abformung) as a very useful technique for fabricating devices with micro-scale structures has been reported to make the micro-pore optics (MPO) for years. Light weight is one of the advantages of MPO, making it an alternative for X-ray focusing lenses used on space telescopes. However, researchers seldom considered using the MPO in visible light region. In this article, we designed a micro-slot optics (MSO) similar to MPO and fabricated it by X-ray LIGA technique. The MSO consists of 159 concentric hollow cylinders of nickel with the slot spacings ranging from 59 to 113 μm and the focusing property of MSO is studied by simulations and experiments. Both the simulation and experiment results indicate that MSO is a useful focusing element. The MSO has one focal point when the point source is on the principal optical axis with the size of the focal point equaling to the size of the point source.

  18. Design of laboratory experiments to study radiation-driven implosions

    Science.gov (United States)

    Keiter, P. A.; Trantham, M.; Malamud, G.; Klein, S. R.; Davis, J.; VanDervort, R.; Shvarts, D.; Drake, R. P.; Stone, J. M.; Fraenkel, M.; Frank, Y.; Raicher, E.

    2017-03-01

    The interstellar medium is heterogeneous with dense clouds amid an ambient medium. Radiation from young OB stars asymmetrically irradiate the dense clouds. Bertoldi (1989) developed analytic formulae to describe possible outcomes of these clouds when irradiated by hot, young stars. One of the critical parameters that determines the cloud's fate is the number of photon mean free paths in the cloud. For the extreme cases where the cloud size is either much greater than or much less than one mean free path, the radiation transport should be well understood. However, as one transitions between these limits, the radiation transport is much more complex and is a challenge to solve with many of the current radiation transport models implemented in codes. We present the design of laboratory experiments that use a thermal source of x-rays to asymmetrically irradiate a low-density plastic foam sphere. The experiment will vary the density and hence the number of mean free paths of the sphere to study the radiation transport in different regimes. We have developed dimensionless parameters to relate the laboratory experiment to the astrophysical system and we show that we can perform the experiment in the same transport regime.

  19. Interactive flutter analysis and parametric study for conceptual wing design

    Science.gov (United States)

    Mukhopadhyay, Vivek

    1995-01-01

    An interactive computer program was developed for wing flutter analysis in the conceptual design stage. The objective was to estimate the flutter instability boundary of a flexible cantilever wing, when well defined structural and aerodynamic data are not available, and then study the effect of change in Mach number, dynamic pressure, torsional frequency, sweep, mass ratio, aspect ratio, taper ratio, center of gravity, and pitch inertia, to guide the development of the concept. The software was developed on MathCad (trademark) platform for Macintosh, with integrated documentation, graphics, database and symbolic mathematics. The analysis method was based on nondimensional parametric plots of two primary flutter parameters, namely Regier number and Flutter number, with normalization factors based on torsional stiffness, sweep, mass ratio, aspect ratio, center of gravity location and pitch inertia radius of gyration. The plots were compiled in a Vaught Corporation report from a vast database of past experiments and wind tunnel tests. The computer program was utilized for flutter analysis of the outer wing of a Blended Wing Body concept, proposed by McDonnell Douglas Corporation. Using a set of assumed data, preliminary flutter boundary and flutter dynamic pressure variation with altitude, Mach number and torsional stiffness were determined.

  20. A new electrodynamic balance design for low temperature studies

    Directory of Open Access Journals (Sweden)

    H.-J. Tong

    2014-07-01

    Full Text Available In this paper we describe a newly designed cold electrodynamic balance (CEDB system, which was built to study the evaporation kinetics and freezing properties of supercooled water droplets. The temperature of the CEDB chamber at the location of the levitated water droplet can be controlled in the range: −40 to +40 °C, which is achieved using a combination of liquid nitrogen cooling and heating by positive temperature coefficient heaters. The measurement of liquid droplet radius is obtained by analyzing the Mie elastic light scattering from a 532 nm laser. The Mie scattering signal was also used to characterize and distinguish droplet freezing events; liquid droplets produce a regular fringe pattern whilst the pattern from frozen particles is irregular. The evaporation rate of singly levitated water droplets was calculated from time resolved measurements of the radii of evaporating droplets and a clear trend of the evaporation rate on temperature was measured. The statistical freezing probabilities of aqueous pollen extracts (pollen washing water are obtained in the temperature range: −4.5 to −40 °C. It was found that that pollen washing water from water birch (Betula fontinalis occidentalis pollen can act as ice nuclei in the immersion freezing mode at temperatures as warm as −22.45 (±0.65 °C.