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Sample records for pre-main sequence pms

  1. Structure and Evolution of Pre-Main Sequence Stars

    CERN Document Server

    Schulz, Norbert S; Bautz, Mark W; Canizares, Claude C; Davis, John; Dewey, Dan; Huenemoerder, David P; Heilmann, Ralf; Houck, John; Marshall, Herman L; Nowak, Mike; Schattenburg, Mark; Audard, Marc; Drake, Jeremy; Gagne, Marc; Kastner, Joel; Kallman, Tim; Lautenegger, Maurice; Lee, Julia; Miller, Jon; Montmerle, Thierry; Mukai, Koji; Osten, Rachel; Parerels, Frits; Pollock, Andy; Preibisch, Thomas; Raymond, John; Reale, Fabio; Smith, Randall; Testa, Paola; Weintraub, David

    2009-01-01

    Low-mass pre-main sequence (PMS) stars are strong and variable X-ray emitters, as has been well established by EINSTEIN and ROSAT observatories. It was originally believed that this emission was of thermal nature and primarily originated from coronal activity (magnetically confined loops, in analogy with Solar activity) on contracting young stars. Broadband spectral analysis showed that the emission was not isothermal and that elemental abundances were non-Solar. The resolving power of the Chandra and XMM X-ray gratings spectrometers have provided the first, tantalizing details concerning the physical conditions such as temperatures, densities, and abundances that characterize the X-ray emitting regions of young star. These existing high resolution spectrometers, however, simply do not have the effective area to measure diagnostic lines for a large number of PMS stars over required to answer global questions such as: how does magnetic activity in PMS stars differ from that of main sequence stars, how do they ...

  2. The coronal evolution of pre-main-sequence stars

    CERN Document Server

    Gregory, Scott G; Davies, Claire L

    2016-01-01

    The bulk of X-ray emission from pre-main-sequence (PMS) stars is coronal in origin. We demonstrate herein that stars on Henyey tracks in the Hertzsprung-Russell diagram have lower $\\log(L_X/L_\\ast)$, on average, than stars on Hayashi tracks. This effect is driven by the decay of $L_X$ once stars develop radiative cores. $L_X$ decays faster with age for intermediate mass PMS stars, the progenitors of main sequence A-type stars, compared to those of lower mass. As almost all main sequence A-type stars show no detectable X-ray emission, we may already be observing the loss of their coronae during their PMS evolution. Although there is no direct link between the size or mass of the radiative core and $L_X$, the longer stars have spent with partially convective interiors, the weaker their X-ray emission becomes. This conference paper is a synopsis of Gregory, Adams and Davies (2016).

  3. Massive pre-main-sequence stars in M17

    Science.gov (United States)

    Ramírez-Tannus, M. C.; Kaper, L.; de Koter, A.; Tramper, F.; Bik, A.; Ellerbroek, L. E.; Ochsendorf, B. B.; Ramírez-Agudelo, O. H.; Sana, H.

    2017-08-01

    The formation process of massive stars is still poorly understood. Massive young stellar objects (mYSOs) are deeply embedded in their parental clouds; these objects are rare, and thus typically distant, and their reddened spectra usually preclude the determination of their photospheric parameters. M17 is one of the best-studied H ii regions in the sky, is relatively nearby, and hosts a young stellar population. We have obtained optical to near-infrared spectra of previously identified candidate mYSOs and a few OB stars in this region with X-shooter on the ESO Very Large Telescope. The large wavelength coverage enables a detailed spectroscopic analysis of the photospheres and circumstellar disks of these candidate mYSOs. We confirm the pre-main-sequence (PMS) nature of six of the stars and characterise the O stars. The PMS stars have radii that are consistent with being contracting towards the main sequence and are surrounded by a remnant accretion disk. The observed infrared excess and the double-peaked emission lines provide an opportunity to measure structured velocity profiles in the disks. We compare the observed properties of this unique sample of young massive stars with evolutionary tracks of massive protostars and propose that these mYSOs near the western edge of the H ii region are on their way to become main-sequence stars ( 6-20 M⊙) after having undergone high mass accretion rates (Ṁacc 10-4-10-3M⊙yr-1). Their spin distribution upon arrival at the zero age main-sequence is consistent with that observed for young B stars, assuming conservation of angular momentum and homologous contraction. Based on observations collected at the European Southern Observatory at Paranal, Chile (ESO programmes 60.A-9404(A), 085.D-0741, 089.C-0874(A), and 091.C-0934(B)).The full normalised X-shooter spectra are available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/604/A78

  4. Theoretical study of $\\gamma$ Doradus pulsations in pre-main sequence stars

    CERN Document Server

    Bouabid, M -P; Miglio, A; Dupret, M -A; Grigahcène, A; Noels, A

    2010-01-01

    The question of the existence of pre-main sequence (PMS) $\\gamma$~Doradus ($\\gamma$~Dor) has been raised by the observations of young clusters such as NGC~884 hosting $\\gamma$~Dor members. We have explored the properties of $\\gamma$~Dor type pulsations in a grid of PMS models covering the mass range $1.2 M_\\odot < M_* < 2.5 M_\\odot$ and we derive the theoretical instability strip (IS) for the PMS $\\gamma$~Dor pulsators. We explore the possibility of distinguishing between PMS and MS $\\gamma$~Dor by the behaviour of the period spacing of their high order $gravity$-modes ($g$-modes).

  5. Lithium Depletion in Fully Convective Pre-Main Sequence Stars

    CERN Document Server

    Bildsten, L; Matzner, C D; Ushomirsky, G; Bildsten, Lars; Brown, Edward F.; Matzner, Christopher D.; Ushomirsky, Greg

    1996-01-01

    We present an analytic calculation of the thermonuclear depletion of lithium in contracting, fully convective, pre-main sequence stars of mass M 0.08 M_sun) and for constraining the masses of lithium depleted stars.

  6. Kinematic Distances of Pre-main Sequence Stars in the Lupus Star-Forming Region

    Science.gov (United States)

    Galli, P. A. B.; Teixeira, R.; Ducourant, C.; Bertout, C.

    2014-06-01

    The problem of the determination of distances has always played a central role in astronomy. However, little recent progress has been made in the distance determination of faint young stellar objects such as pre-main sequence (PMS) stars. Many of the PMS stars were neither observed by the Hipparcos satellite due to their magnitude nor have any trigonometric parallax measured from the ground due to their distance. Here we investigate the kinematic properties of the Lupus moving group with the primary objective of deriving individual parallaxes for each group member of this star-forming region.

  7. Pulsating pre-main sequence stars in IC 4996 and NGC 6530

    CERN Document Server

    Zwintz, K; Zwintz, Konstanze; Weiss, Werner W.

    2006-01-01

    Asteroseismology of pulsating pre-main sequence (PMS) stars has the potential of testing the validity of current models of PMS structure and evolution. As a first step, a sufficiently large sample of pulsating PMS stars has to be established, which allows to select candidates optimally suited for a detailed asteroseismological analysis based on photometry from space or ground based network data. A search for pulsating PMS members in the young open clusters IC 4996 and NGC 6530 has been performed to improve the sample of known PMS pulsators. As both clusters are younger than 10 million years, all members with spectral types later than A0 have not reached the zero-age main sequence yet. Hence, IC 4996 and NGC 6530 are most suitable to search for PMS pulsation among their A- and F-type cluster stars. CCD time series photometry in Johnson B and V filters has been obtained for IC 4996 and NGC 6530. The resulting light curves for 113 stars in IC 4996 and 194 stars in NGC 6530 have been subject to detailed frequency...

  8. THE HABITABLE ZONES OF PRE-MAIN-SEQUENCE STARS

    Energy Technology Data Exchange (ETDEWEB)

    Ramirez, Ramses M.; Kaltenegger, Lisa [Institute for Pale Blue Dots, Cornell University, Ithaca, NY (United States)

    2014-12-20

    We calculate the pre-main-sequence habitable zone (HZ) for stars of spectral classes F-M. The spatial distribution of liquid water and its change during the pre-main-sequence phase of protoplanetary systems is important for understanding how planets become habitable. Such worlds are interesting targets for future missions because the coolest stars could provide habitable conditions for up to 2.5 billion years post-accretion. Moreover, for a given star type, planetary systems are more easily resolved because of higher pre-main-sequence stellar luminosities, resulting in larger planet-star separation for cool stars than is the case for the traditional main-sequence (MS) HZ. We use one-dimensional radiative-convective climate and stellar evolutionary models to calculate pre-main-sequence HZ distances for F1-M8 stellar types. We also show that accreting planets that are later located in the traditional MS HZ orbiting stars cooler than a K5 (including the full range of M stars) receive stellar fluxes that exceed the runaway greenhouse threshold, and thus may lose substantial amounts of water initially delivered to them. We predict that M-star planets need to initially accrete more water than Earth did, or, alternatively, have additional water delivered later during the long pre-MS phase to remain habitable. Our findings are also consistent with recent claims that Venus lost its water during accretion.

  9. The Habitable Zones of Pre-Main-Sequence Stars

    CERN Document Server

    Ramirez, Ramses M

    2014-01-01

    We calculate the pre-main-sequence HZ for stars of spectral classes F to M. The spatial distribution of liquid water and its change during the pre-main-sequence phase of protoplanetary systems is important in understanding how planets become habitable. Such worlds are interesting targets for future missions because the coolest stars could provide habitable conditions for up to 2.5 billion years post-accretion. Moreover, for a given star type, planetary systems are more easily resolved because of higher pre-main-sequence stellar luminosities, resulting in larger planet to star separation for cool stars than is the case for the traditional main-sequence (MS) habitable zone (HZ). We use 1D radiative-convective climate and stellar evolutionary models to calculate pre-main-sequence HZ distances for F1 to M8 stellar types. We also show that accreting planets that are later located in the traditional MS HZ orbiting stars cooler than a K5 (including the full range of M-stars) receive stellar fluxes that exceed the ru...

  10. Theoretical seismic properties of pre-main sequence gamma Doradus pulsators

    CERN Document Server

    Bouabid, M -P; Miglio, A; Dupret, M -A; Grigahcene, A; Noels, A

    2011-01-01

    Context. gamma Doradus (gamma Dor) are late A and F-type stars pulsating with high order gravity modes (g-modes). The existence of different evolutionary phases crossing the gamma Dor instability strip raises the question of the existence of pre-main sequence (PMS) gamma Dor stars. Aims. We intend to study the differences between the asteroseismic behaviour of PMS and main sequence (MS) gamma Dor pulsators as it is predicted by the current theory of stellar evolution and stability. Methods. We explore the adiabatic and non-adiabatic properties of high order g-modes in a grid of PMS and MS models covering the mass range 1.2 Msun < Mstar < 2.5 Msun. Results. We derive the theoretical instability strip (IS) for the PMS gamma Dor pulsators. This IS covers the same effective temperature range as the MS gamma Dor one. Nevertheless, the frequency domain of unstable modes in PMS models with a fully radiative core is larger than in MS models, even if they present the same number of unstable modes. Moreover, the ...

  11. YSOVAR: SIX PRE-MAIN-SEQUENCE ECLIPSING BINARIES IN THE ORION NEBULA CLUSTER

    Energy Technology Data Exchange (ETDEWEB)

    Morales-Calderon, M.; Stauffer, J. R.; Rebull, L. M. [Spitzer Science Center, California Institute of Technology, 1200 E California Blvd., Pasadena, CA 91125 (United States); Stassun, K. G. [Physics and Astronomy Department, Vanderbilt University, 1807 Station B, Nashville, TN 37235 (United States); Vrba, F. J. [U. S. Naval Observatory, Flagstaff Station, 10391 W. Naval Observatory Road, Flagstaff, AZ 86001-8521 (United States); Prato, L. [Lowell Observatory, 1400 West Mars Hill Road, Flagstaff, AZ 86001 (United States); Hillenbrand, L. A.; Carpenter, J. M. [Astronomy Department, California Institute of Technology, 1200 E California Blvd., Pasadena, CA 91125 (United States); Terebey, S.; Angione, J. [Department of Physics and Astronomy, California State University at Los Angeles, Los Angeles, CA 90032 (United States); Covey, K. R. [Department of Astronomy, Cornell University, 226 Space Sciences Building, Ithaca, NY 14853 (United States); Terndrup, D. M. [Department of Astronomy, The Ohio State University, 140 West 18th Avenue, Columbus, OH 43210 (United States); Gutermuth, R. [Department of Astronomy, University of Massachusetts, Amherst, MA 01003 (United States); Song, I. [Physics and Astronomy Department, University of Georgia, Athens, GA 30602-2451 (United States); Plavchan, P. [NASA Exoplanet Science Institute, California Institute of Technology, Pasadena, CA 91125 (United States); Marchis, F. [SETI Institute, Carl Sagan Center, 189 N San Bernado Av, Mountain View, CA 94043 (United States); Garcia, E. V. [Department of Physics, Fisk University, 1000 17th Ave. N, Nashville, TN 37208 (United States); Margheim, S. [Gemini Observatory, Southern Operations Center, Casilla 603, La Serena (Chile); Luhman, K. L. [Department of Astronomy and Astrophysics, The Pennsylvania State University, University Park, PA 16802 (United States); Irwin, J. M., E-mail: mariamc@cab.inta-csic.es [Harvard-Smithsonian Center for Astrophysics, 60 Garden St., Cambridge, MA 02138 (United States)

    2012-07-10

    Eclipsing binaries (EBs) provide critical laboratories for empirically testing predictions of theoretical models of stellar structure and evolution. Pre-main-sequence (PMS) EBs are particularly valuable, both due to their rarity and the highly dynamic nature of PMS evolution, such that a dense grid of PMS EBs is required to properly calibrate theoretical PMS models. Analyzing multi-epoch, multi-color light curves for {approx}2400 candidate Orion Nebula Cluster (ONC) members from our Warm Spitzer Exploration Science Program YSOVAR, we have identified 12 stars whose light curves show eclipse features. Four of these 12 EBs are previously known. Supplementing our light curves with follow-up optical and near-infrared spectroscopy, we establish two of the candidates as likely field EBs lying behind the ONC. We confirm the remaining six candidate systems, however, as newly identified ONC PMS EBs. These systems increase the number of known PMS EBs by over 50% and include the highest mass ({theta}{sup 1} Ori E, for which we provide a complete set of well-determined parameters including component masses of 2.807 and 2.797 M{sub Sun }) and longest-period (ISOY J053505.71-052354.1, P {approx} 20 days) PMS EBs currently known. In two cases ({theta}{sup 1} Ori E and ISOY J053526.88-044730.7), enough photometric and spectroscopic data exist to attempt an orbit solution and derive the system parameters. For the remaining systems, we combine our data with literature information to provide a preliminary characterization sufficient to guide follow-up investigations of these rare, benchmark systems.

  12. Are pre-main-sequence stars older than we thought?

    CERN Document Server

    Naylor, Tim

    2009-01-01

    We fit the colour-magnitude diagrams of stars between the zero-age main-sequence and terminal-age main sequence in young clusters and associations. The ages we derive are a factor 1.5 to 2 longer than the commonly used ages for these regions, which are derived from the positions of pre-main-sequence stars in colour-magnitude diagrams. From an examination of the uncertainties in the main-sequence and pre-main-sequence models, we conclude that the longer age scale is probably the correct one, which implies we must revise upwards the commonly used ages for young clusters and associations. Such a revision would explain the discrepancy between the observational lifetimes of proto-planetary discs and theoretical calculations of the time to form planets. It would also explain the absence of clusters with ages between 5 and 30Myr. We use the $\\tau^2$ statistic to fit the main-sequence data, but find that we must make significant modifications if we are to fit sequences which have vertical segments in the colour-magni...

  13. Pre-main-sequence isochrones -- I. The Pleiades benchmark

    CERN Document Server

    Bell, Cameron P M; Mayne, N J; Jeffries, R D; Littlefair, S P

    2012-01-01

    We present a critical assessment of commonly used pre-main-sequence isochrones by comparing their predictions to a set of well-calibrated colour-magnitude diagrams of the Pleiades in the wavelength range 0.4 to 2.5 microns. Our analysis shows that for temperatures less than 4000 K the models systematically overestimate the flux by a factor two at 0.5 microns, though this decreases with wavelength, becoming negligible at 2.2 microns. In optical colours this will result in the ages for stars younger than 10 Myr being underestimated by factors between two and three. We show that using observations of standard stars to transform the data into a standard system can introduce significant errors in the positioning of pre-main-sequences in colour-magnitude diagrams. Therefore we have compared the models to the data in the natural photometric system in which the observations were taken. Thus we have constructed and tested a model of the system responses for the Wide-Field Camera on the Isaac Newton Telescope. As a ben...

  14. Evidence of accretion triggered oscillations in the pre-main-sequence interacting binary AK Sco

    CERN Document Server

    de Castro, Ana I Gomez; Talavera, Antonio

    2012-01-01

    Pre-main sequence (PMS) binaries are surrounded by circumbinary disks from which matter falls onto both components. The material dragged from the circumbinary disk flows onto each star through independent streams channelled by the variable gravitational field. The action of the bar-like potential is most prominent in high eccentricity systems made of two equal mass stars. AK Sco is a unique PMS system composed of two F5 stars in an orbit with e=0.47. Henceforth, it is an ideal laboratory to study matter infall in binaries and its role in orbit circularization. In this letter, we report the detection of a 1.3mHz ultra low frequency oscillation in the ultraviolet light curve at periastron passage. This oscillation last 7 ks being most likely fed by the gravitational energy released when the streams tails spiralling onto each star get in contact at periastron passage enhancing the accretion flow; this unveils a new mechanism for angular momentum loss during pre-main sequence evolution and a new type of interacti...

  15. Low-mass pre--main-sequence stars in the Magellanic Clouds

    CERN Document Server

    Gouliermis, Dimitrios

    2012-01-01

    [Abridged] The stellar Initial Mass Function (IMF) suggests that sub-solar stars form in very large numbers. Most attractive places for catching low-mass star formation in the act are young stellar clusters and associations, still (half-)embedded in star-forming regions. The low-mass stars in such regions are still in their pre--main-sequence (PMS) evolutionary phase. The peculiar nature of these objects and the contamination of their samples by the evolved populations of the Galactic disk impose demanding observational techniques for the detection of complete numbers of PMS stars in the Milky Way. The Magellanic Clouds, the companion galaxies to our own, demonstrate an exceptional star formation activity. The low extinction and stellar field contamination in star-forming regions of these galaxies imply a more efficient detection of low-mass PMS stars than in the Milky Way, but their distance from us make the application of special detection techniques unfeasible. Nonetheless, imaging with the Hubble Space Te...

  16. Gaia-ESO Survey: The analysis of pre-main sequence stellar spectra

    CERN Document Server

    Lanzafame, A C; Damiani, F; Franciosini, E; Cottaar, M; Sousa, S G; Tabernero, H M; Klutsch, A; Spina, L; Biazzo, K; Prisinzano, L; Sacco, G G; Randich, S; Brugaletta, E; Mena, E Delgado; Adibekyan, V; Montes, D; Bonito, R; Gameiro, J F; Alcalá, J M; Hernández, J I González; Jeffries, R; Messina, S; Meyer, M; Gilmore, G; Asplund, M; Binney, J; Bonifacio, P; Drew, J E; Feltzing, S; Ferguson, A M N; Micela, G; Negueruela, I; Prusti, T; Rix, H-W; Vallenari, A; Alfaro, E J; Prieto, C Allende; Babusiaux, C; Bensby, T; Blomme, R; Bragaglia, A; Flaccomio, E; Francois, P; Hambly, N; Irwin, M; Koposov, S E; Korn, A J; Smiljanic, R; Van Eck, S; Walton, N; Bayo, A; Bergemann, M; Carraro, G; Costado, M T; Edvardsson, B; Heiter, U; Hill, V; Hourihane, A; Jackson, R J; Jofré, P; Lardo, C; Lewis, J; Lind, K; Magrini, L; Marconi, G; Martayan, C; Masseron, T; Monaco, L; Morbidelli, L; Sbordone, L; Worley, C C; Zaggia, S

    2015-01-01

    This paper describes the analysis of UVES and GIRAFFE spectra acquired by the Gaia-ESO Public Spectroscopic Survey in the fields of young clusters whose population includes pre-main sequence (PMS) stars. Both methods that have been extensively used in the past and new ones developed in the contest of the Gaia-ESO survey enterprise are available and used. The internal precision of these quantities is estimated by inter-comparing the results obtained by such different methods, while the accuracy is estimated by comparison with independent external data, like effective temperature and surface gravity derived from angular diameter measurements, on a sample of benchmarks stars. Specific strategies are implemented to deal with fast rotation, accretion signatures, chromospheric activity, and veiling. The analysis carried out on spectra acquired in young clusters' fields during the first 18 months of observations, up to June 2013, is presented in preparation of the first release of advanced data products. Stellar par...

  17. The effect of starspots on the radii of low-mass pre-main sequence stars

    CERN Document Server

    Jackson, R J

    2014-01-01

    A polytropic model is used to investigate the effects of dark photospheric spots on the evolution and radii of magnetically active, low-mass (M<0.5Msun), pre-main sequence (PMS) stars. Spots slow the contraction along Hayashi tracks and inflate the radii of PMS stars by a factor of (1-beta)^{-N} compared to unspotted stars of the same luminosity, where beta is the equivalent covering fraction of dark starspots and N \\simeq 0.45+/-0.05. This is a much stronger inflation than predicted by the models of Spruit & Weiss (1986) for main sequence stars with the same beta, where N \\sim 0.2 to 0.3. These models have been compared to radii determined for very magnetically active K- and M-dwarfs in the young Pleiades and NGC 2516 clusters, and the radii of tidally-locked, low-mass eclipsing binary components. The binary components and ZAMS K-dwarfs have radii inflated by \\sim 10 per cent compared to an empirical radius-luminosity relation that is defined by magnetically inactive field dwarfs with interferometrica...

  18. A probable pre-main sequence chemically peculiar star in the open cluster Stock 16

    CERN Document Server

    Netopil, M; Paunzen, E; Zwintz, K; Pintado, O I; Bagnulo, S

    2014-01-01

    We used the Ultraviolet and Visual Echelle Spectrograph of the ESO-Very Large Telescope to obtain a high resolution and high signal-to-noise ratio spectrum of Stock 16-12, an early-type star which previous Delta-a photometric observations suggest being a chemically peculiar (CP) star. We used spectral synthesis to perform a detailed abundance analysis obtaining an effective temperature of 8400 +/- 400 K, a surface gravity of 4.1 +/- 0.4, a microturbulence velocity of 3.4 +0.7/-0.3 km/s, and a projected rotational velocity of 68 +/- 4 km/s. We provide photometric and spectroscopic evidence showing the star is most likely a member of the young Stock 16 open cluster (age 3-8 Myr). The probable cluster membership, the star's position in the Hertzsprung-Russell diagram, and the found infrared excess strongly suggest the star is still in the pre-main-sequence (PMS) phase. We used PMS evolutionary tracks to determine the stellar mass, which ranges between 1.95 and 2.3 Msun, depending upon the adopted spectroscopic o...

  19. Pre-main sequence stars older than 8 Myr in the Eagle Nebula

    CERN Document Server

    De Marchi, Guido; Guarcello, M G; Bonito, Rosaria

    2013-01-01

    Attention is given to a population of 110 stars in the NGC 6611 cluster of the Eagle Nebula that have prominent near-infrared (NIR) excess and optical colours typical of pre-main sequence (PMS) stars older than 8 Myr. At least half of those for which spectroscopy exists have a Halpha emission line profile revealing active accretion. In principle, the V-I colours of all these stars would be consistent with those of young PMS objects (< 1 Myr) whose radiation is heavily obscured by a circumstellar disc seen at high inclination and in small part scattered towards the observer by the back side of the disc. However, using theoretical models it is shown here that objects of this type can only account for a few percent of this population. In fact, the spatial distribution of these objects, their X-ray luminosities, their optical brightness, their positions in the colour-magnitude diagram and the weak Li absorption lines of the stars studied spectroscopically suggest that most of them are at least 8 times older th...

  20. THE QUADRUPLE PRE-MAIN-SEQUENCE SYSTEM LkCa 3: IMPLICATIONS FOR STELLAR EVOLUTION MODELS

    Energy Technology Data Exchange (ETDEWEB)

    Torres, Guillermo; Latham, David W. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Ruiz-Rodriguez, Dary; Prato, L.; Wasserman, Lawrence H. [Lowell Observatory, 1400 West Mars Hill Road, Flagstaff, AZ 86001 (United States); Badenas, Mariona [Department of Astronomy, Yale University, New Haven, CT 06520 (United States); Schaefer, G. H. [CHARA Array of Georgia State University, Mount Wilson Observatory, Mount Wilson, CA 91023 (United States); Mathieu, Robert D., E-mail: gtorres@cfa.harvard.edu [Department of Astronomy, University of Wisconsin-Madison, Madison, WI 53706 (United States)

    2013-08-10

    We report the discovery that the pre-main-sequence (PMS) object LkCa 3 in the Taurus-Auriga star-forming region is a hierarchical quadruple system of M stars. It was previously known to be a close ({approx}0.''5) visual pair, with one component being a moderately eccentric 12.94 day single-lined spectroscopic binary. A re-analysis of archival optical spectra complemented by new near-infrared (NIR) spectroscopy shows both visual components to be double lined; the second one has a period of 4.06 days and a circular orbit. In addition to the orbital elements, we determine optical and NIR flux ratios, effective temperatures, and projected rotational velocities for all four stars. Using existing photometric monitoring observations of the system that had previously revealed the rotational period of the primary in the longer-period binary, we also detect the rotational signal of the primary in the 4.06 day binary, which is synchronized with the orbital motion. With only the assumption of coevality, a comparison of all of these constraints with current stellar evolution models from the Dartmouth series points to an age of 1.4 Myr and a distance of 133 pc, consistent with previous estimates for the region and suggesting that the system is on the near side of the Taurus complex. Similar comparisons of the properties of LkCa 3 and the well-known quadruple PMS system GG Tau with the widely used models from the Lyon series for a mixing length parameter of {alpha}{sub ML} = 1.0 strongly favor the Dartmouth models.

  1. The influence of radiative core growth on coronal X-ray emission from pre-main sequence stars

    CERN Document Server

    Gregory, Scott G; Davies, Claire L

    2016-01-01

    Pre-main sequence (PMS) stars of mass $\\gtrsim0.35\\,{\\rm M}_\\odot$ transition from hosting fully convective interiors to configurations with a radiative core and outer convective envelope during their gravitational contraction. This stellar structure change influences the external magnetic field topology and, as we demonstrate herein, affects the coronal X-ray emission as a stellar analog of the solar tachocline develops. We have combined archival X-ray, spectroscopic, and photometric data for $\\sim$1000 PMS stars from five of the best studied star forming regions; the ONC, NGC 2264, IC 348, NGC 2362, and NGC 6530. Using a modern, PMS calibrated, spectral type-to-effective temperature and intrinsic colour scale, we deredden the photometry using colours appropriate for each spectral type, and determine the stellar mass, age, and internal structure consistently for the entire sample. We find that PMS stars on Henyey tracks have, on average, lower fractional X-ray luminosities ($L_{\\rm X}/L_\\ast$) than those on ...

  2. Hunting for millimeter flares from magnetic reconnection in pre-main sequence spectroscopic binaries

    CERN Document Server

    Kóspál, Á; Hogerheijde, M R; Moór, A; Blake, G A

    2010-01-01

    Recent observations of the low-mass pre-main sequence, eccentric spectroscopic binaries DQ Tau and V773 Tau A reveal that their millimeter spectrum is occasionally dominated by flares from non-thermal emission processes. The transient activity is believed to be synchrotron in nature, resulting from powerful magnetic reconnection events when the separate magnetic structures of the binary components are capable of interacting and forced to reorganize, typically near periastron. We conducted the first systematic study of the millimeter variability toward a sample of 12 PMS spectroscopic binaries with the aim to characterize the proliferation of flares amongst sources likely to experience similar interbinary reconnection events. The source sample consists of short-period, close-separation binaries that possess either a high orbital eccentricity or a circular orbit. Using the MAMBO2 array on the IRAM 30m telescope, we carried out continuous monitoring at 1.25 mm over a 4-night period during which all of the high-e...

  3. Deep near-IR variability survey of pre-main-sequence stars in Rho Ophiuchi

    CERN Document Server

    de Oliveira, Catarina Alves

    2008-01-01

    Variability is a common characteristic of pre-main-sequence stars (PMS). Near-IR variability surveys of young stellar objects (YSOs) can probe stellar and circumstellar environments and provide information about the dynamics of the on going magnetic and accretion processes. Furthermore, variability can be used as a tool to uncover new cluster members in star formation regions. We hope to achieve the deepest near-IR variability study of YSOs targeting the Rho Ophiuchi cluster. Fourteen epochs of observations were obtained with the Wide Field Camera (WFCAM) at the UKIRT telescope scheduled in a manner that allowed the study of variability on timescales of days, months, and years. Statistical tools, such as the multi-band cross correlation index and the reduced chi-square, were used to disentangle signals of variability from noise. Variability characteristics are compared to existing models of YSOs in order to relate them to physical processes, and then used to select new candidate members of this star-forming r...

  4. The Effect of Pre-Main Sequence Stars on Star Cluster Dynamics

    CERN Document Server

    Wiersma, R; Zwart, S P

    2006-01-01

    We investigate the effects of the addition of pre-main sequence evolution to star cluster simulations. We allowed stars to follow pre-main sequence tracks that begin at the deuterium burning birthline and end at the zero age main sequence. We compared our simulations to ones in which the stars began their lives at the zero age main sequence, and also investigated the effects of particular choices for initial binary orbital parameters. We find that the inclusion of the pre-main sequence phase results in a slightly higher core concentration, lower binary fraction, and fewer hard binary systems. In general, the global properties of star clusters remain almost unchanged, but the properties of the binary star population in the cluster can be dramatically modified by the correct treatment of the pre-main sequence stage.

  5. Pre-main sequence accretion in the low metallicity Galactic star-forming region Sh 2-284

    CERN Document Server

    Kalari, V M

    2014-01-01

    We present optical spectra of pre-main sequence (PMS) candidates around the H$\\alpha$ region taken with the Southern African Large Telescope, SALT, in the low metallicity ($Z$) Galactic region Sh 2-284, which includes the open cluster Dolidze 25 with an atypical low metallicity of $Z$ $\\sim$ 1/5 $Z_{\\odot}$. It has been suggested on the basis of both theory and observations that PMS mass-accretion rates, $\\dot M_{\\rm{acc}}$, are a function of $Z$. We present the first sample of spectroscopic estimates of mass-accretion rates for PMS stars in any low-$Z$ star-forming region. Our data-set was enlarged with literature data of H$\\alpha$ emission in intermediate-resolution R-band spectroscopy. Our total sample includes 24 objects spanning a mass range between 1 - 2 $M_{\\odot}$ and with a median age of approximately 3.5 Myr. The vast majority (21 out of 24) show evidence for a circumstellar disk on the basis of 2MASS and Spitzer infrared photometry. We find $\\dot M_{\\rm{acc}}$ in the 1 - 2 $M_{\\odot}$ interval to d...

  6. Measuring the mass of a pre-main sequence binary star through the orbit of TWA5A

    Energy Technology Data Exchange (ETDEWEB)

    Konopacky, Q; Ghez, A; Duchene, G; McCabe, C; Macintosh, B

    2007-01-18

    We present the results of a five year monitoring campaign of the close binary TWA 5Aab in the TW Hydrae association, using speckle and adaptive optics on the W.M. Keck 10 m telescopes. These measurements were taken as part of our ongoing monitoring of pre-main sequence (PMS) binaries in an effort to increase the number of dynamically determined PMS masses and thereby calibrate the theoretical PMS evolutionary tracks. Our observations have allowed us to obtain the first determination of this system's astrometric orbit. We find an orbital period of 5.94 {+-} 0.09 years and a semi-major axis of 0.''066 {+-} 0.''005. Combining these results with a kinematic distance, we calculate a total mass of 0.71 {+-} 0.14 M{sub {circle_dot}} (D/44 pc){sup 3}. for this system. This mass measurement, as well as the estimated age of this system, are consistent to within 2{sigma} of all theoretical models considered. In this analysis, we properly account for correlated uncertainties, and show that while these correlations are generally ignored, they increase the formal uncertainties by up to a factor of five and therefore are important to incorporate. With only a few more years of observation, this type of measurement will allow the theoretical models to be distinguished.

  7. Hunting for millimeter flares from magnetic reconnection in pre-main sequence spectroscopic binaries

    Science.gov (United States)

    Kóspál, Á.; Salter, D. M.; Hogerheijde, M. R.; Moór, A.; Blake, G. A.

    2011-03-01

    Context. Recent observations of the low-mass pre-main sequence (PMS), eccentric spectroscopic binaries DQ Tau and V773 Tau A reveal that their millimeter spectrum is occasionally dominated by flares from non-thermal emission processes. The transient activity is believed to be synchrotron in nature, resulting from powerful magnetic reconnection events when the separate magnetic structures of the binary components are briefly capable of interacting and forced to reorganize, typically near periastron. Aims: We conducted the first systematic study of the millimeter variability toward a sample of 12 PMS spectroscopic binaries with the aim to characterize the proliferation of flares amongst sources likely to experience similar interbinary reconnection events. The source sample consists entirely of short-period, close-separation binaries that possess either a high orbital eccentricity (e > 0.1) or a circular orbit (e ≈ 0). Methods: Using the MAMBO2 array on the IRAM 30 m telescope, we carried out continuous monitoring at 1.25 mm (240 GHz) over a 4-night period during which all of the high-eccentricity binaries approached periastron. We also obtained simultaneous optical VRI measurements, since a strong link is often observed between stellar reconnection events (traced via X-rays) and optical brightenings. Results: UZ Tau E is the only source to be detected at millimeter wavelengths, and it exhibited significant variation (F1.25mm = 87-179 mJy); it is also the only source to undergo strong simultaneous optical variability (ΔR ≈ 0.9 mag). The binary possesses the largest orbital eccentricity in the current sample, a predicted factor in star-star magnetic interaction events. With orbital parameters and variable accretion activity similar to DQ Tau, the millimeter behavior of UZ Tau E draws many parallels to the DQ Tau model for colliding magnetospheres. However, on the basis of our observations alone, we cannot determine whether the variability is repetitive, or if it

  8. Pulsation of Pre-Main Sequence Stars in Young Open Clusters

    Science.gov (United States)

    Zwintz, Konstanze; Weiss, Werner W.

    2001-08-01

    The aim of this proposal is to determine observationally the parameter space of the pre-main sequence instability strip. For that purpose we intend to obtain photometric timeseries with high time resolution and low noise level of the stars in young open clusters (IC 4996, NGC 6910 and NGC 6383) and to identify pre-main sequence pulsators. Several cluster members have the spectral types of interest (A-F) and lie between the birthline and the zero-age main sequence. Up to now the number of pre-main sequence pulsators is absolutely inadequate to determine reliably the hot and cool border of the according instability region. Its definition is indispensable for a better understanding of the internal structure and evolution of such stars.

  9. Pre-Main sequence Turn-On as a chronometer for young clusters: NGC346 as a benchmark

    CERN Document Server

    Cignoni, M; Sabbi, E; Nota, A; Degl'Innocenti, S; Moroni, P G Prada; Gallagher, J S

    2010-01-01

    We present a novel approach to derive the age of very young star clusters, by using the Turn-On (TOn). The TOn is the point in the color-magnitude diagram (CMD) where the pre-main sequence (PMS) joins the main sequence (MS). In the MS luminosity function (LF) of the cluster, the TOn is identified as a peak followed by a dip. We propose that by combining the CMD analysis with the monitoring of the spatial distribution of MS stars it is possible to reliably identify the TOn in extragalactic star forming regions. Compared to alternative methods, this technique is complementary to the turn-off dating and avoids the systematic biases affecting the PMS phase. We describe the method and its uncertainties, and apply it to the star forming region NGC346, which has been extensively imaged with the Hubble Space Telescope (HST). This study extends the LF approach in crowded extragalactic regions and opens the way for future studies with HST/WFC3, JWST and from the ground with adaptive optics.

  10. Impact of internal gravity waves on the rotation profile inside pre-main sequence low-mass stars

    CERN Document Server

    Charbonnel, C; Amard, L; Palacios, A; Talon, S

    2013-01-01

    We study the impact of internal gravity waves (IGW), meridional circulation, shear turbulence, and stellar contraction on the internal rotation profile and surface velocity evolution of solar metallicity low-mass pre-main sequence stars. We compute a grid of rotating stellar evolution models with masses between 0.6 and 2.0Msun taking these processes into account for the transport of angular momentum, as soon as the radiative core appears and assuming no more disk-locking from that moment on.IGW generation along the PMS is computed taking Reynolds-stress and buoyancy into account in the bulk of the stellar convective envelope and convective core (when present). Redistribution of angular momentum within the radiative layers accounts for damping of prograde and retrograde IGW by thermal diffusivity and viscosity in corotation resonance. Over the whole mass range considered, IGW are found to be efficiently generated by the convective envelope and to slow down the stellar core early on the PMS. In stars more massi...

  11. On the origin of the correlations between the accretion luminosity and emission line luminosities in pre-main-sequence stars

    Science.gov (United States)

    Mendigutía, I.; Oudmaijer, R. D.; Rigliaco, E.; Fairlamb, J. R.; Calvet, N.; Muzerolle, J.; Cunningham, N.; Lumsden, S. L.

    2015-09-01

    Correlations between the accretion luminosity and emission line luminosities (Lacc and Lline) of pre-main-sequence (PMS) stars have been published for many different spectral lines, which are used to estimate accretion rates. Despite the origin of those correlations is unknown, this could be attributed to direct or indirect physical relations between the emission line formation and the accretion mechanism. This work shows that all (near-UV/optical/near-IR) Lacc-Lline correlations are the result of the fact that the accretion luminosity and the stellar luminosity (L*) are correlated, and are not necessarily related with the physical origin of the line. Synthetic and observational data are used to illustrate how the Lacc-Lline correlations depend on the Lacc-L* relationship. We conclude that because PMS stars show the Lacc-L* correlation immediately implies that Lacc also correlates with the luminosity of all emission lines, for which the Lacc-Lline correlations alone do not prove any physical connection with accretion but can only be used with practical purposes to roughly estimate accretion rates. When looking for correlations with possible physical meaning, we suggest that Lacc/L* and Lline/L* should be used instead of Lacc and Lline. Finally, the finding that Lacc has a steeper dependence on L* for T Tauri stars than for intermediate-mass Herbig Ae/Be stars is also discussed. That is explained from the magnetospheric accretion scenario and the different photospheric properties in the near-UV.

  12. On the origin of the correlations between the accretion luminosity and emission line luminosities in pre-main sequence stars

    CERN Document Server

    Mendigutía, I; Rigliaco, E; Fairlamb, J R; Calvet, N; Muzerolle, J; Cunningham, N; Lumsden, S L

    2015-01-01

    Correlations between the accretion luminosity and emission line luminosities (L_acc and L_line) of pre-main sequence (PMS) stars have been published for many different spectral lines, which are used to estimate accretion rates. Despite the origin of those correlations is unknown, this could be attributed to direct or indirect physical relations between the emission line formation and the accretion mechanism. This work shows that all (near-UV/optical/near-IR) L_acc-L_line correlations are the result of the fact that the accretion luminosity and the stellar luminosity (L_star) are correlated, and are not necessarily related with the physical origin of the line. Synthetic and observational data are used to illustrate how the L_acc-L_line correlations depend on the L_acc-L_star relationship. We conclude that because PMS stars show the L_acc-L_star correlation immediately implies that L_acc also correlates with the luminosity of all emission lines, for which the L_acc-L_line correlations alone do not prove any phy...

  13. Photometric determination of the mass accretion rate of pre-main sequence stars. IV. Recent star formation in NGC 602

    CERN Document Server

    De Marchi, Guido; Panagia, Nino

    2013-01-01

    We have studied the young stellar populations in NGC 602, in the Small Magellanic Cloud, using a novel method that we have developed to combine Hubble Space Telescope photometry in the V, I, and Halpha bands. We have identified about 300 pre-main sequence (PMS) stars, all of which are still undergoing active mass accretion, and have determined their physical parameters (effective temperature, luminosity, age, mass and mass accretion rate). Our analysis shows that star formation has been present in this field over the last 60 Myr. In addition, we can recognise at least two clear, distinct, and prominent episodes in the recent past: one about 2 Myr ago, but still ongoing in regions of higher nebulosity, and one (or more) older than 30 Myr, encompassing both stars dispersed in the field and two smaller clusters located about 100 arcsec north of the centre of NGC 602. The relative locations of younger and older PMS stars do not imply a causal effect or triggering of one generation on the other. The strength of th...

  14. An Internet server for update pre-main sequence tracks of low- and intermediate-mass stars

    CERN Document Server

    Siess, L; Forestini, M

    2000-01-01

    We present new grids of pre-main sequence (PMS) tracks for stars in the mass range 0.1 to 7.0 Msun. The computations were performed for four different metallicities (Z=0.01, 0.02, 0.03 and 0.04). A fifth table has been computed for the solar composition (Z=0.02), including a moderate overshooting. We describe the update in the physics of the Grenoble stellar evolution code which concerns mostly changes in the equation of state (EOS) adopting the formalism proposed by Pols et al. (1995) and in the treatment of the boundary condition. Comparisons of our models with other grids demonstrate the validity of this EOS in the domain of very low-mass stars. Finally, we present a new server dedicated to PMS stellar evolution which allows the determination of stellar parameters from observational data, the calculation of isochrones, the retrieval of evolutionary files and the possibility to generate graphic outputs. WWW site : http://www-laog.obs.ujf-grenoble.fr/activites/starevol/evol.html

  15. The clustered nature of star formation. Pre--main-sequence clusters in the star-forming region NGC 602/N90 in the Small Magellanic Cloud

    CERN Document Server

    Gouliermis, Dimitrios A; Dolphin, Andrew E; Gennaro, Mario; Tognelli, Emanuele; Moroni, Pier Giorgio Prada

    2012-01-01

    Located at the tip of the wing of the Small Magellanic Cloud (SMC), the star-forming region NGC602/N90 is characterized by the HII nebular ring N90 and the young cluster of pre--main-sequence (PMS) and early-type main sequence stars NGC602. We present a thorough cluster analysis of the stellar sample identified with HST/ACS camera in the region. We show that apart from the central cluster, low-mass PMS stars are congregated in thirteen additional small compact sub-clusters at the periphery of NGC602. We find that the spatial distribution of the PMS stars is bimodal, with an unusually large fraction (~60%) of the total population being clustered, while the remaining is diffusely distributed in the inter-cluster area. From the corresponding color-magnitude diagrams we disentangle an age-difference of ~2.5Myr between NGC602 and the compact sub-clusters which appear younger. The diffuse PMS population appears to host stars as old as those in NGC602. Almost all detected PMS sub-clusters appear to be centrally conc...

  16. A constraint on the formation timescale of the young open cluster NGC 2264: Lithium abundance of pre-main sequence stars

    CERN Document Server

    Lim, Beomdu; Kim, Jinyoung S; Bessell, Michael S; Hwang, Narae; Park, Byeong-Gon

    2016-01-01

    The timescale of cluster formation is an essential parameter in order to understand the formation process of star clusters. Pre-main sequence (PMS) stars in nearby young open clusters reveal a large spread in brightness. If the spread were considered as a result of a real spread in age, the corresponding cluster formation timescale would be about 5 -- 20 Myr. Hence it could be interpreted that star formation in an open cluster is prolonged for up to a few tens of Myr. However, difficulties in reddening correction, observational errors, and systematic uncertainties introduced by imperfect evolutionary models for PMS stars, can result in an artificial age spread. Alternatively, we can utilize Li abundance as a relative age indicator of PMS star to determine the cluster formation timescale. The optical spectra of 134 PMS stars in NGC 2264 have been obtained with MMT/Hectochelle. The equivalent widths have been measured for 86 PMS stars with a detectable Li line (3500 < T_eff [K] <= 6500). Li abundance unde...

  17. EXPORT optical photometry and polarimetry of Vega-type and pre-main sequence stars

    CERN Document Server

    Oudmaijer, R D; Eiroa, C

    2001-01-01

    This paper presents optical UBVRI broadband photo-polarimetry of the EXPORT sample obtained at the 2.5m Nordic Optical Telescope. The database consists of multi-epoch photo-polarimetry of 68 pre-main-sequence and main-sequence stars. An investigation of the polarization variability indicates that 22 objects are variable at the 3sigma level in our data. All these objects are pre-main sequence stars, consisting of both T Tauri and Herbig Ae/Be objects while the main sequence, Vega type and post-T Tauri type objects are not variable. The polarization properties of the variable sources are mostly indicative of the UXOR-type behaviour; the objects show highest polarization when the brightness is at minimum. We add seven new objects to the class of UXOR variables (BH Cep, VX Cas, DK Tau, HK Ori, LkHa 234, KK Oph and RY Ori). The main reason for their discovery is the fact that our data-set is the largest in its kind, indicating that many more young UXOR-type pre-main sequence stars remain to be discovered. The set ...

  18. Pre main sequence stars as UV sources for the World Space Observatory-UV mission

    Science.gov (United States)

    Gomez de Castro, Ana I.; Lamzin, Sergei A.

    2011-09-01

    Pre-main sequence stars are bright UV (UV) sources compared with their main sequence analogues. The source of this excess is the high energy processes associated with the physics of accretion/outflow during early stellar evolution. In this review, the main sources of UV excess are described as well as the most significant "unknowns" in the field. Special emphasis is made on the results from the last observations carried out with the Hubble Space Telescope and on the relevance of future dedicated monitoring programs with the World Space Observatory-UV.

  19. A New Method for the Assessment of Age and Age-Spread of Pre-Main Sequence Stars in Young Stellar Associations of the Magellanic Clouds

    CERN Document Server

    Da Rio, Nicola; Gennaro, Mario

    2010-01-01

    We present a new method for the evaluation of the age and age-spread among pre-main-sequence (PMS) stars in star-forming regions in the Magellanic Clouds, accounting simultaneously for photometric errors, unresolved binarity, differential extinction, stellar variability, accretion and crowding. The application of the method is performed with the statistical construction of synthetic color-magnitude diagrams using PMS evolutionary models. We convert each isochrone into 2D probability distributions of artificial PMS stars in the CMD by applying the aforementioned biases that dislocate these stars from their original CMD positions. A maximum-likelihood technique is then applied to derive the probability for each observed star to have a certain age, as well as the best age for the entire cluster. We apply our method to the photometric catalog of ~2000 PMS stars in the young association LH 95 in the LMC, based on the deepest HST/ACS imaging ever performed toward this galaxy, with a detection limit of V~28, corresp...

  20. The potential of space observations for pulsating pre-main sequence stars

    CERN Document Server

    Zwintz, Konstanze

    2016-01-01

    The first asteroseismic studies of pre-main sequence (pre-MS) pulsators have been conducted based on data from the space telescopes MOST and CoRoT with typical time bases of less than 40 days. With these data, a relation between the pulsational properties of pre-MS delta Scuti stars and their relative evolutionary phase on their way from the birthline to the zero-age main sequence was revealed. But it is evident from comparison with the more evolved pulsators in their main sequence or post-main sequence stages observed by the main Kepler mission, that many more questions could be addressed with significantly longer time bases and ultra-high precision. Here, I will discuss the observational status of pre-MS asteroseismology and the potential of future space observations for this research field.

  1. Differential rotation on both components of the pre main-sequence binary system HD 155555

    OpenAIRE

    Dunstone, N. J.; Hussain, G A J; Cameron, A. Collier; Marsden, S. C.; Jardine, M.; Barnes, J. R.; Vlex, J. C. Ramirez; Donati, J.-F.

    2008-01-01

    We present the first measurements of surface differential rotation on a pre-main sequence binary system. Using intensity (Stokes I) and circularly polarised (Stokes V) timeseries spectra, taken over eleven nights at the Anglo-Australian Telescope (AAT), we incorporate a solar-like differential rotation law into the surface imaging process. We find that both components of the young, 18 Myr, HD 155555 (V824 Ara, G5IV + K0IV) binary system show significant differential rotation. The equator-pole...

  2. Active phenomena in the pre-main sequence Herbig Ae star HD 163296

    Science.gov (United States)

    Catala, C.; Praderie, F.; Simon, T.; Talavera, A.; The, P. S.

    1989-01-01

    Observations by IUE of the short-term variability of the Mg II and Ca II resonance lines in the Herbig Ae star HD 163296 are presented. Evidence that these lines show a phenomenon of rotational modulation, similar to the one observed in AB Aur, another Herbig Ae star is found. The variations in the spectrum of HD 163296 are even more conspicuous than in the spectrum of AB Aur. Magnetically structured winds may thus be a widespread phenomenon among the pre-main sequence Herbig Ae/Be stars.

  3. Pre-main sequence variable stars in young open cluster NGC 1893

    OpenAIRE

    Lata, Sneh; Pandey, A.K.(Indian Institute of Technology Bombay (IIT), Mumbai, India); Chen, W. P.; Maheswar, G.; Chauhan, Neelam

    2012-01-01

    We present results of multi-epoch (fourteen nights during 2007-2010) $V$-band photometry of the cluster NGC 1893 region to identify photometric variable stars in the cluster. The study identified a total of 53 stars showing photometric variability. The members associated with the region are identified on the basis of spectral energy distribution, $J-H/H-K$ two colour diagram and $V/V-I$ colour-magnitude diagram. The ages and masses of the majority of pre-main-sequence sources are found to be ...

  4. The first magnetic maps of a pre-main sequence binary star system - HD 155555

    OpenAIRE

    Dunstone, N. J.; Hussain, G. A. J.; Cameron, A. Collier; Marsden, S. C.; Jardine, M.; Stempels, H. C.; Vlex, J. C. Ramirez; Donati, J. -F.

    2008-01-01

    We present the first maps of the surface magnetic fields of a pre-main sequence binary system. Spectropolarimetric observations of the young, 18 Myr, HD 155555 (V824 Ara, G5IV + K0IV) system were obtained at the Anglo-Australian Telescope in 2004 and 2007. Both datasets are analysed using a new binary Zeeman Doppler imaging (ZDI) code. This allows us to simultaneously model the contribution of each component to the observed circularly polarised spectra. Stellar brightness maps are also produc...

  5. Differential rotation on both components of the pre main-sequence binary system HD 155555

    OpenAIRE

    Dunstone, N. J.; Hussain, G. A. J.; Cameron, A. Collier; Marsden, S. C.; Jardine, M.; Barnes, J.R.; Vlex, J. C. Ramirez; Donati, J. -F.

    2008-01-01

    We present the first measurements of surface differential rotation on a pre-main sequence binary system. Using intensity (Stokes I) and circularly polarised (Stokes V) timeseries spectra, taken over eleven nights at the Anglo-Australian Telescope (AAT), we incorporate a solar-like differential rotation law into the surface imaging process. We find that both components of the young, 18 Myr, HD 155555 (V824 Ara, G5IV + K0IV) binary system show significant differential rotation. The equator-pole...

  6. THE CLUSTERED NATURE OF STAR FORMATION. PRE-MAIN-SEQUENCE CLUSTERS IN THE STAR-FORMING REGION NGC 602/N90 IN THE SMALL MAGELLANIC CLOUD

    Energy Technology Data Exchange (ETDEWEB)

    Gouliermis, Dimitrios A.; Gennaro, Mario [Max Planck Institute for Astronomy, Koenigstuhl 17, 69117 Heidelberg (Germany); Schmeja, Stefan [Zentrum fuer Astronomie der Universitaet Heidelberg, Institut fuer Theoretische Astrophysik, Albert-Ueberle-Str. 2, 69120 Heidelberg (Germany); Dolphin, Andrew E. [Raytheon Company, P.O. Box 11337, Tucson, AZ 85734 (United States); Tognelli, Emanuele; Prada Moroni, Pier Giorgio [Dipartimento di Fisica ' Enrico Fermi' , Universita di Pisa, largo Pontecorvo 3, Pisa I-56127 (Italy)

    2012-03-20

    Located at the tip of the wing of the Small Magellanic Cloud (SMC), the star-forming region NGC 602/N90 is characterized by the H II nebular ring N90 and the young cluster of pre-main-sequence (PMS) and early-type main-sequence stars NGC 602, located in the central area of the ring. We present a thorough cluster analysis of the stellar sample identified with Hubble Space Telescope/Advanced Camera for Surveys in the region. We show that apart from the central cluster low-mass PMS stars are congregated in 13 additional small, compact sub-clusters at the periphery of NGC 602, identified in terms of their higher stellar density with respect to the average background density derived from star counts. We find that the spatial distribution of the PMS stars is bimodal, with an unusually large fraction ({approx}60%) of the total population being clustered, while the remaining is diffusely distributed in the intercluster area, covering the whole central part of the region. From the corresponding color-magnitude diagrams we disentangle an age difference of {approx}2.5 Myr between NGC 602 and the compact sub-clusters, which appear younger, on the basis of comparison of the brighter PMS stars with evolutionary models, which we accurately calculated for the metal abundance of the SMC. The diffuse PMS population appears to host stars as old as those in NGC 602. Almost all detected PMS sub-clusters appear to be centrally concentrated. When the complete PMS stellar sample, including both clustered and diffused stars, is considered in our cluster analysis, it appears as a single centrally concentrated stellar agglomeration, covering the whole central area of the region. Considering also the hot massive stars of the system, we find evidence that this agglomeration is hierarchically structured. Based on our findings, we propose a scenario according to which the region NGC 602/N90 experiences an active clustered star formation for the last {approx}5 Myr. The central cluster NGC 602 was

  7. An Unusual Eclipse of a Pre-Main Sequence Star in IC 348

    CERN Document Server

    Cohen, R E; Williams, E C

    2003-01-01

    A solar-like pre-main sequence star (TJ 108 = H 187 = LRLL 35 = HMW 15) in the extremely young cluster IC 348 has been found, which apparently experienced an eclipse lasting ~3.5 years, much longer than has ever been detected for any normal eclipsing binary. The light curve is flat-bottomed and rather symmetric, with a depth of 0.66 mag in Cousins I. During eclipse, the system reddened by \\~0.17 mag in R-I. We argue that the eclipsing body is not a star because of the small probability of detecting an eclipse in what would be a very widely separated binary. Instead, it appears that the eclipse was caused by a circumstellar or circumbinary cloud or disk feature which occulted the star, or one of its components, if it is a binary system. We emphasize the importance of more detailed study of this object, which appears to be a new member of a small class of pre-main sequence stars whose variability can be firmly linked to occultation by circumstellar (or circumbinary) matter.

  8. ACCRETION RATES ON PRE-MAIN-SEQUENCE STARS IN THE YOUNG OPEN CLUSTER NGC 6530

    Energy Technology Data Exchange (ETDEWEB)

    Gallardo, Jose; Del Valle, Luciano; Ruiz, Maria Teresa, E-mail: gallardo@das.uchile.cl, E-mail: ldelvall@das.uchile.cl, E-mail: mtruiz@das.uchile.cl [Departamento de Astronomia, Universidad de Chile, Casilla 36-D, Santiago (Chile)

    2012-01-15

    It is well accepted that during the star formation process, material from a protoplanetary disk is accreted onto the central object during the first {approx}1-5 Myr. Different authors have published measurements of accretion rates for young low- and intermediate-mass stars in several nearby star-forming regions (SFRs). Due to its somewhat larger distance, the SFR M8 (the Lagoon Nebula) has not been studied to the same extent, despite its abundant population of young stellar objects. We have obtained optical band low-resolution spectra of a sample of pre-main-sequence stars in the open cluster NGC 6530 located in the aforementioned nebulae using the Gemini Multi Object Spectrograph at Gemini-South in multi-object mode. Spectra cover the H{sub {alpha}} emission line used to measure the accretion rate, following the method presented by Natta et al. The observed spectral characteristics are fully consistent with pre-main-sequence stars, showing lithium absorption lines, which are very common in young stellar objects, as well as prominent and broad H{sub {alpha}} emission lines, indicating a T Tauri evolutionary stage. This work presents the first determinations of mass accretion rates of young stellar objects in the open cluster NGC 6530, confirming that they are classical T Tauri stars going through the accretion phase. These observations contribute to a better understanding of the stellar content and evolutionary phase of the very active Lagoon Nebula SFR.

  9. Pre-main sequence stars in the stellar association N11 in the Large Magellanic Cloud

    CERN Document Server

    Vallenari, Antonella; Sordo, Rosanna

    2009-01-01

    Magellanic Clouds are of extreme importance to the study of the star formation process in low metallicity environments. In this paper we report on the discovery of pre-main sequence candidates and young embedded stellar objects in N11 located in the Large Magellanic Cloud to cast light on the star formation scenario. We would like to remind that this comparison is complicated by the presence of a large age dispersion detected in the fields. Deep archive HST/ACS photometry is used to derive color-magnitude diagrams of the associations in N~11 and of the foreground field population. These data are complemented by archive IR Spitzer data which allow the detection of young embedded stellar objects. The spatial distribution of the pre-main sequence candidates and young embedded stellar objects is compared with literature data observed at different wavelengths, such as H$_{\\alpha}$ and CO maps, and with the distribution of OB and Herbig Ae/Be stars. The degree of clustering is derived using the Minimal Spanning Tre...

  10. KH 15D: Gradual Occultation of a Pre-Main-Sequence Binary

    CERN Document Server

    Winn, J N; Johnson, J A; Stanek, K Z; Garnavich, P M; Winn, Joshua N.; Holman, Matthew J.; Johnson, John A.; Stanek, Krzysztof Z.; Garnavich, Peter M.

    2004-01-01

    We propose that the extraordinary "winking star" KH 15D is an eccentric pre-main-sequence binary that is gradually being occulted by an opaque screen. This model accounts for the periodicity, depth, duration, and rate of growth of the modern eclipses; the historical light curve from photographic plates; and the existing radial velocity measurements. It also explains the re-brightening events that were previously observed during mid-eclipse, and the subsequent disappearance of these events. We predict the future evolution of the system and its full radial velocity curve. Given the small velocity of the occulting screen relative to the center of mass of the binary, the screen is probably associated with the binary, and may be the edge of a precessing circumbinary disk.

  11. New radio detections of early-type pre-main-sequence stars

    Science.gov (United States)

    Skinner, Stephen L.; Brown, Alexander; Linsky, Jeffrey L.

    1990-01-01

    Results of VLA radio continuum observations of 13 early-type pre-main-sequence stars selected from the 1984 catalog of Finkenzeller and Mundt are presented. The stars HD 259431 and MWC 1080 were detected at 3.6 cm, while HD 200775 and TY CrA were detected at both 3.6 and 6 cm. The flux density of HD 200775 has a frequency dependence consistent with the behavior expected for free-free emission originating in a fully ionized wind. However, an observation in A configuration suggests that the source geometry may not be spherically symmetric. In contrast, the spectral index of TY CrA is negative with a flux behavior implying nonthermal emission. The physical mechanism responsible for the nonthermal emission has not yet been identified, although gyrosynchrotron and synchrotron processes cannot be ruled out.

  12. The magnetic field of the pre-main sequence Herbig Ae star HD 190073

    Science.gov (United States)

    Catala, C.; Alecian, E.; Donati, J.-F.; Wade, G. A.; Landstreet, J. D.; Böhm, T.; Bouret, J.-C.; Bagnulo, S.; Folsom, C.; Silvester, J.

    2007-01-01

    Context: The general context of this paper is the study of magnetic fields in the pre-main sequence intermediate mass Herbig Ae/Be stars. Magnetic fields are likely to play an important role in pre-main sequence evolution at these masses, in particular in controlling the gains and losses of stellar angular momentum. Aims: The particular aim of this paper is to announce the detection of a structured magnetic field in the Herbig Ae star HD 190073, and to discuss various scenarii for the geometry of the star, its environment and its magnetic field. Methods: We have used the ESPaDOnS spectropolarimeter at CFHT in 2005 and 2006 to obtain high-resolution, high signal-to-noise circular polarization spectra which demonstrate unambiguously the presence of a magnetic field in the photosphere of this star. Results: Nine circular polarization spectra were obtained, each one showing a clear Zeeman signature. This signature is suggestive of a magnetic field structured on large scales. The signature, which corresponds to a longitudinal magnetic field of 74± 10 G, does not vary detectably on a one-year timeframe, indicating either an azimuthally symmetric field, a zero inclination angle between the rotation axis and the line of sight, or a very long rotation period. The optical spectrum of HD 190073 exhibits a large number of emission lines. We discuss the formation of these emission lines in the framework of a model involving a turbulent heated region at the base of the stellar wind, possibly powered by magnetic accretion. Conclusions: .This magnetic detection contributes an important new observational discovery which will aid our understanding of stellar magnetism at intermediate masses. Based on observations obtained at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique of France, and the University of Hawaii.

  13. Revisiting the pre-main-sequence evolution of stars. I. Importance of accretion efficiency and deuterium abundance

    Science.gov (United States)

    Kunitomo, Masanobu; Guillot, Tristan; Takeuchi, Taku; Ida, Shigeru

    2017-03-01

    Context. Protostars grow from the first formation of a small seed and subsequent accretion of material. Recent theoretical work has shown that the pre-main-sequence (PMS) evolution of stars is much more complex than previously envisioned. Instead of the traditional steady, one-dimensional solution, accretion may be episodic and not necessarily symmetrical, thereby affecting the energy deposited inside the star and its interior structure. Aims: Given this new framework, we want to understand what controls the evolution of accreting stars. Methods: We use the MESA stellar evolution code with various sets of conditions. In particular, we account for the (unknown) efficiency of accretion in burying gravitational energy into the protostar through a parameter, ξ, and we vary the amount of deuterium present. Results: We confirm the findings of previous works that, in terms of evolutionary tracks on an Hertzprung-Russell (H-R) diagram, the evolution changes significantly with the amount of energy that is lost during accretion. We find that deuterium burning also regulates the PMS evolution. In the low-entropy accretion scenario, the evolutionary tracks in the H-R diagram are significantly different from the classical tracks and are sensitive to the deuterium content. A comparison of theoretical evolutionary tracks and observations allows us to exclude some cold accretion models (ξ 0) with low deuterium abundances. Conclusions: We confirm that the luminosity spread seen in clusters can be explained by models with a somewhat inefficient injection of accretion heat. The resulting evolutionary tracks then become sensitive to the accretion heat efficiency, initial core entropy, and deuterium content. In this context, we predict that clusters with a higher D/H ratio should have less scatter in luminosity than clusters with a smaller D/H. Future work on this issue should include radiation-hydrodynamic simulations to determine the efficiency of accretion heating and further

  14. Pre-main-sequence isochrones -- II. Revising star and planet formation timescales

    CERN Document Server

    Bell, Cameron P M; Mayne, N J; Jeffries, R D; Littlefair, S P

    2013-01-01

    We have derived ages for 13 young (<30 Myr) star-forming regions and find they are up to a factor two older than the ages typically adopted in the literature. This result has wide-ranging implications, including that circumstellar discs survive longer (~10-12 Myr) and that the average Class I lifetime is greater (~1 Myr) than currently believed. For each star-forming region we derived two ages from colour-magnitude diagrams. First we fitted models of the evolution between the zero-age main-sequence and terminal-age main-sequence to derive a homogeneous set of main-sequence ages, distances and reddenings with statistically meaningful uncertainties. Our second age for each star-forming region was derived by fitting pre-main-sequence stars to new semi-empirical model isochrones. For the first time (for a set of clusters younger than 50 Myr) we find broad agreement between these two ages, and since these are derived from two distinct mass regimes that rely on different aspects of stellar physics, it gives us c...

  15. Can we predict the global magnetic topology of a pre-main sequence star from its position in the Hertzsprung-Russell diagram?

    CERN Document Server

    Gregory, S G; Morin, J; Hussain, G A J; Mayne, N J; Hillenbrand, L A; Jardine, M

    2012-01-01

    ZDI studies have shown that the magnetic fields of T Tauri stars can be significantly more complex than a simple dipole and can vary markedly between sources. We collect and summarize the magnetic field topology information obtained to date and present Hertzsprung-Russell (HR) diagrams for the stars in the sample. Intriguingly, the large scale field topology of a given pre-main sequence (PMS) star is strongly dependent upon the stellar internal structure, with the strength of the dipole component of its multipolar magnetic field decaying rapidly with the development of a radiative core. Using the observational data as a basis, we argue that the general characteristics of the global magnetic field of a PMS star can be determined from its position in the HR diagram. Moving from hotter and more luminous to cooler and less luminous stars across the PMS of the HR diagram, we present evidence for four distinct magnetic topology regimes. Stars with large radiative cores, empirically estimated to be those with a core...

  16. A High-Resolution Multiband Survey of Westerlund 2 With the Hubble Space Telescope. II. Mass accretion in the Pre-Main Sequence Population

    CERN Document Server

    Zeidler, Peter; Nota, Antonella; Sabbi, Elena; Pasquali, Anna; Tosi, Monica; Bonanos, Alceste Z; Christian, Carol

    2016-01-01

    We present a detailed analysis of the pre-main-sequence (PMS) population of the young star cluster Westerlund~2 (Wd2), the central ionizing cluster of the HII region RCW 49, using data from a high resolution multi-band survey with the Hubble Space Telescope. The data were acquired with the Advanced Camera for Surveys in the F555W, F814W, and F658N filters and with the Wide Field Camera 3 in the F125W, F160W, and F128N filters. We find a mean age of the region of 1.04+-0.72 Myr. The combination of dereddened F555W and F814W photometry in combination with F658N photometry allows us to study and identify stars with H_alpha excess emission. With a careful selection of 240 bona-fide PMS H_alpha excess emitters we were able to determine their H_alpha luminosity, which has a mean value L(H_alpha)=1.67 x 10^{-31} erg s^{-1}. Using the PARSEC 1.2S isochrones to obtain the stellar parameters of the PMS stars we determined a mean mass accretion rate \\dot M_acc=4.43 x 10^{-8} M_sun yr^{-1} per star. A careful analysis of...

  17. Differential rotation on both components of the pre main-sequence binary system HD 155555

    CERN Document Server

    Dunstone, N J; Cameron, A Collier; Marsden, S C; Jardine, M; Barnes, J R; Vlex, J C Ramirez; Donati, J -F

    2008-01-01

    We present the first measurements of surface differential rotation on a pre-main sequence binary system. Using intensity (Stokes I) and circularly polarised (Stokes V) timeseries spectra, taken over eleven nights at the Anglo-Australian Telescope (AAT), we incorporate a solar-like differential rotation law into the surface imaging process. We find that both components of the young, 18 Myr, HD 155555 (V824 Ara, G5IV + K0IV) binary system show significant differential rotation. The equator-pole laptimes as determined from the intensity spectra are 80 days for the primary star and 163 days for the secondary. Similarly for the magnetic spectra we obtain equator-pole laptimes of 44 and 71 days respectively, showing that the shearing timescale of magnetic regions is approximately half that found for stellar spots. Both components are therefore found to have rates of differential rotation similar to those of the same spectral type main sequence single stars. The results for HD 155555 are therefore in contrast to tho...

  18. Pre-main-sequence isochrones -- III. The Cluster Collaboration isochrone server

    CERN Document Server

    Bell, Cameron P M; Naylor, Tim; Mayne, N J; Jeffries, R D; Mamajek, Eric E; Rowe, John

    2014-01-01

    We present an isochrone server for semi-empirical pre-main-sequence model isochrones in the following systems: Johnson-Cousins, Sloan Digital Sky Survey, Two-Micron All-Sky Survey, Isaac Newton Telescope (INT) Wide-Field Camera, and INT Photometric H$\\alpha$ Survey (IPHAS)/UV-Excess Survey (UVEX). The server can be accessed via the Cluster Collaboration webpage {http://www.astro.ex.ac.uk/people/timn/isochrones/}. To achieve this we have used the observed colours of member stars in young clusters with well-established age, distance and reddening to create fiducial loci in the colour-magnitude diagram. These empirical sequences have been used to quantify the discrepancy between the models and data arising from uncertainties in both the interior and atmospheric models, resulting in tables of semi-empirical bolometric corrections (BCs) in the various photometric systems. The model isochrones made available through the server are based on existing stellar interior models coupled with our newly derived semi-empiric...

  19. Magnetic Activity of Pre-main Sequence Stars near the Stellar-Substellar Boundary

    CERN Document Server

    Principe, David A; Rodriguez, David

    2015-01-01

    X-ray observations of pre-main sequence (pre-MS) stars of M-type probe coronal emission and offer a means to investigate magnetic activity at the stellar-substellar boundary. Recent observations of main sequence (MS) stars at this boundary display a decrease in fractional X-ray luminosity ($L_{X}$/$L_{bol}$) by almost two orders of magnitude for spectral types M7 and later. We investigate magnetic activity and search for a decrease in X-ray emission in the pre-MS progenitors of these MS stars. We present XMM-Newton X-ray observations and preliminary results for ~10 nearby (30-70 pc), very low mass pre-MS stars in the relatively unexplored age range of 10-30 Myr. We compare the fractional X-ray luminosities of these 10-30 Myr old stars to younger (1-3 Myr) pre-MS brown dwarfs and find no dependence on spectral type or age suggesting that X-ray activity declines at an age later than ~30 Myr in these very low-mass stars.

  20. Magnetic Activity of Pre-main Sequence Stars near the Stellar-Substellar Boundary

    Science.gov (United States)

    Principe, David; Kastner, Joel. H.; Rodriguez, David

    2016-01-01

    X-ray observations of pre-main sequence (pre-MS) stars of M-type probe coronal emission and offer a means to investigate magnetic activity at the stellar-substellar boundary. Recent observations of main sequence (MS) stars at this boundary display a decrease in fractional X-ray luminosity (L X /L bol ) by almost two orders of magnitude for spectral types M7 and later. We investigate magnetic activity and search for a decrease in X-ray emission in the pre-MS progenitors of these MS stars. We present XMM-Newton X-ray observations and preliminary results for ~10 nearby (30-70 pc), very low mass pre-MS stars in the relatively unexplored age range of 10-30 Myr. We compare the fractional X-ray luminosities of these 10-30 Myr old stars to younger (1-3 Myr) pre-MS brown dwarfs and find no dependence on spectral type or age suggesting that X-ray activity declines at an age later than ~30 Myr in these very low-mass stars.

  1. Photometric Determination of the Mass Accretion Rates of Pre-main-sequence Stars. V. Recent Star Formation in the 30 Dor Nebula

    Science.gov (United States)

    De Marchi, Guido; Panagia, Nino; Beccari, Giacomo

    2017-09-01

    We report on the properties of the low-mass stars that recently formed in the central ∼ 2\\buildrel{ \\prime}\\over{.} 7× 2\\buildrel{ \\prime}\\over{.} 7 of 30 Dor, including the R136 cluster. Using the photometric catalog of De Marchi et al., based on observations with the Hubble Space Telescope, and the most recent extinction law for this field, we identify 1035 bona fide pre-main-sequence (PMS) stars showing {{H}}α excess emission at the 4σ level with an {{H}}α equivalent width of 20 Å or more. We find a wide spread in age spanning the range ∼ 0.1{--}50 {Myr}. We also find that the older PMS objects are placed in front of the R136 cluster and are separated from it by a conspicuous amount of absorbing material, indicating that star formation has proceeded from the periphery into the interior of the region. We derive physical parameters for all PMS stars, including masses m, ages t, and mass accretion rates {\\dot{M}}{acc}. To identify reliable correlations between these parameters, which are intertwined, we use a multivariate linear regression fit of the type {log}{\\dot{M}}{acc}=a× {log}t+b× {log}m+c. The values of a and b for 30 Dor are compatible with those found in NGC 346 and NGC 602. We extend the fit to a uniform sample of 1307 PMS stars with 0.5contract NAS5-26555.

  2. Pre-main-sequence binaries with tidally disrupted discs: the Br gamma in HD 104237

    CERN Document Server

    Garcia, P J V; Dougados, C; Bacciotti, F; Clausse, J -M; Massi, F; Mérand, A; Petrov, R; Weigelt, G

    2013-01-01

    Active pre-main-sequence binaries with separations of around ten stellar radii present a wealth of phenomena unobserved in common systems. The study of these objects is extended from Classical T Tauri stars to the Herbig Ae star HD 104237. Spectro-interferometry with the VLTI/AMBER is presented. It is found that the K-band continuum squared visibilities are compatible with a circumbinary disc with a radius of ~0.5 AU. However, a significant fraction (~50 per cent) of the flux is unresolved and not fully accounted by the stellar photospheres. The stars probably don't hold circumstellar discs, in addition to the circumbinary disk, due to the combined effects of inner magnetospheric truncation and outer tidal truncation. This unresolved flux likely arises in compact structures inside the tidally disrupted circumbinary disc. Most ($\\gtrsim 90$ per cent) of the Br gamma line emission is unresolved. The line-to-continuum spectro-astrometry shifts in time, along the direction of the Ly alpha jet known to be driven b...

  3. The first magnetic maps of a pre-main sequence binary star system - HD 155555

    CERN Document Server

    Dunstone, N J; Cameron, A Collier; Marsden, S C; Jardine, M; Stempels, H C; Vlex, J C Ramirez; Donati, J -F

    2008-01-01

    We present the first maps of the surface magnetic fields of a pre-main sequence binary system. Spectropolarimetric observations of the young, 18 Myr, HD 155555 (V824 Ara, G5IV + K0IV) system were obtained at the Anglo-Australian Telescope in 2004 and 2007. Both datasets are analysed using a new binary Zeeman Doppler imaging (ZDI) code. This allows us to simultaneously model the contribution of each component to the observed circularly polarised spectra. Stellar brightness maps are also produced for HD 155555 and compared to previous Doppler images. Our radial magnetic maps reveal a complex surface magnetic topology with mixed polarities at all latitudes. We find rings of azimuthal field on both stars, most of which are found to be non-axisymmetric with the stellar rotational axis. We also examine the field strength and the relative fraction of magnetic energy stored in the radial and azimuthal field components at both epochs. A marked weakening of the field strength of the secondary star is observed between t...

  4. Exploring pre-main sequence variables of ONC: The new variables

    CERN Document Server

    Parihar, Padmakar; Distefano, Elisa; Shantikumar N S; Medhi, Biman J

    2009-01-01

    Since 2004, we have been engaged in a long-term observing program to monitor young stellar objects in the Orion Nebula Cluster. We have collected about two thousands frames in V, R, and I broad-band filters on more than two hundred nights distributed over five consecutive observing seasons. The high-quality and time-extended photometric data give us an opportunity to address various phenomena associated with young stars. The prime motivations of this project are i) to explore various manifestations of stellar magnetic activity in very young low-mass stars; ii) to search for new pre-main sequence eclipsing binaries; and iii) to look for any EXor and FUor like transient activities associated with YSOs. Since this is the first paper on this program, we give a detailed description of the science drivers, the observation and the data reduction strategies as well. In addition to these, we also present a large number of new periodic variables detected from our first five years of time-series photometric data. Our st...

  5. V4046 Sgr: Touchstone to Investigate Spectral Type Discrepancies for Pre-main Sequence Stars

    CERN Document Server

    Kastner, Joel H; Sargent, Benjamin; Smith, C T; Rayner, John

    2014-01-01

    Determinations of the fundamental properties (e.g., masses and ages) of late-type, pre-main sequence (pre-MS) stars are complicated by the potential for significant discrepancies between the spectral types of such stars as ascertained via optical vs. near-infrared observations. To address this problem, we have obtained near-IR spectroscopy of the nearby, close binary T Tauri system V4046 Sgr AB with the NASA Infrared Telescope Facility (IRTF) SPEX spectrometer. The V4046 Sgr close binary (and circumbinary disk) system provides an important test case for spectral type determination thanks to the stringent observational constraints on its component stellar masses (i.e., ~0.9 Msun each) as well as on its age (12-21 Myr) and distance (73 pc). Analysis of the IRTF data indicates that the composite near-IR spectral type for V4046 Sgr AB lies in the range M0-M1, i.e., significantly later than the K5+K7 composite type previously determined from optical spectroscopy. However, the K5+K7 composite type is in better agre...

  6. Tracing the potential planet-forming regions around seven pre-main-sequence stars

    CERN Document Server

    Schegerer, A A; Hummel, C A; Quanz, S P; Richichi, A

    2009-01-01

    We investigate the nature of the innermost regions of seven circumstellar disks around pre-main-sequence stars. Our object sample contains disks apparently at various stages of their evolution. Both single stars and spatially resolved binaries are considered. In particular, we search for inner disk gaps as proposed for several young stellar objects. When analyzing the underlying dust population in the atmosphere of circumstellar disks, the shape of the 10um feature is investigated. We performed interferometric observations in N band 8-13um with MIDI using baseline lengths of between 54m and 127m. The data analysis is based on radiative-transfer simulations using the Monte Carlo code MC3D by modeling simultaneously the SED, N band spectra, and interferometric visibilities. Correlated and uncorrelated N band spectra are compared to investigate the radial distribution of the dust composition of the disk atmosphere. Spatially resolved mid-infrared emission was detected in all objects. For four objects, the observ...

  7. RX J0942.7-7726AB: an isolated pre-main sequence wide binary

    CERN Document Server

    Murphy, Simon J; Bessell, Michael S

    2012-01-01

    We report the discovery of two young M-dwarfs, RX J0942.7-7726 (M1) and 2MASS J09424157-7727130 (M4.5), that were found only 42 arcsec apart in a survey for pre-main sequence stars surrounding the open cluster eta Chamaeleontis. Both stars have congruent proper motions and near-infrared photometry. Medium-resolution spectroscopy reveals that they are coeval (age 8-12 Myr), codistant (100-150 pc) and thus almost certainly form a true wide binary with a projected separation of 4000-6000 AU. The system appears too old and dynamically fragile to have originated in eta Cha and a traceback analysis argues for its birth in or near the Scorpius-Centaurus OB Association. RX J0942.7-7726AB joins a growing group of wide binaries kinematically linked to Sco-Cen, suggesting that such fragile systems can survive the turbulent environment of their natal molecular clouds while still being dispersed with large velocities. Conversely, the small radial velocity difference between the stars (2.7 \\pm 1.0 km/s) could mean the syst...

  8. The quadruple pre-main sequence system LkCa3: Implications for stellar evolution models

    CERN Document Server

    Torres, Guillermo; Badenas, Mariona; Prato, L; Schaefer, G H; Wasserman, Lawrence H; Mathieu, Robert D; Latham, David W

    2013-01-01

    We report the discovery that the pre-main sequence object LkCa3 in the Taurus-Auriga star-forming region is a hierarchical quadruple system of M stars. It was previously known to be a close (~0.5 arc sec) visual pair, with one component being a moderately eccentric 12.94-day single-lined spectroscopic binary. A re-analysis of archival optical spectra complemented with new near-infrared spectroscopy shows both visual components to be double-lined, the second one having a period of 4.06 days and a circular orbit. In addition to the orbital elements, we determine optical and near-infrared flux ratios, effective temperatures, and projected rotational velocities for all four stars. Using existing photometric monitoring observations of the system that had previously revealed the rotational period of the primary in the longer-period binary, we detect also the rotational signal of the primary in the 4.06-day binary, which is synchronized with the orbital motion. With only the assumption of coevality, a comparison of ...

  9. Older and Colder: The impact of starspots on pre-main sequence stellar evolution

    CERN Document Server

    Somers, Garrett

    2015-01-01

    We assess the impact of starspots on the evolution of late-type stars during the pre-main sequence (pre-MS) using a modified stellar evolution code. We find that heavily spotted models of mass 0.1-1.2\\msun\\ are inflated by up to $10$% during the pre-MS, and up to 4% and 9% for fully- and partially-convective stars at the zero-age MS, consistent with measurements from active eclipsing binary systems. Spots similarly decrease stellar luminosity and $T_{\\rm eff}$, causing isochrone-derived masses to be under-estimated by up to a factor of $2 \\times$, and ages to be under-estimated by a factor of 2-10$\\times$, at 3 Myr. Consequently, pre-MS clusters and their active stars are systematically older and more massive than often reported. Cluster ages derived with the lithium depletion boundary technique are erroneously young by $\\sim 15$% and $10$% at $30$ and $100$ Myr respectively, if 50% spotted stars are interpreted with un-spotted models. Finally, lithium depletion is suppressed in spotted stars with radiative c...

  10. The Recurrent Eclipse of an Unusual Pre--Main-Sequence Star in IC 348

    CERN Document Server

    Nordhagen, S; Williams, E C; Semkov, E

    2006-01-01

    The recurrence of a previously documented eclipse of a solar-like pre--main-sequence star in the young cluster IC 348 has been observed. The recurrence interval is 4.7 $\\pm 0.1$ yr and portions of 4 cycles have now been seen. The duration of each eclipse is at least 3.5 years, or $\\sim 75$% of a cycle, verifying that this is not an eclipse by a stellar companion. The light curve is generally symmetric and approximately flat-bottomed. Brightness at maximum and minimum have been rather stable over the years but the light curve is not perfectly repetitive or smooth and small variations exist at all phases. We confirm that the star is redder when fainter. Models are discussed and it is proposed that this could be a system similar to KH 15D in NGC 2264. Specifically, it may be an eccentric binary in which a portion of the orbit of one member is currently occulted during some binary phases by a circumbinary disk. The star deserves sustained observational attention for what it may reveal about the circumstellar envi...

  11. Fundamental properties of pre-main sequence stars in young, southern star forming regions: metallicities

    CERN Document Server

    James, D J; Santos, N C; Bouvier, J; James, David J.; Melo, Claudio; Santos, Nuno C.; Bouvier, Jerome

    2005-01-01

    Aims: The primary motivation for this project is to search for metal-rich star forming regions, in which, stars of super-solar metallicity will be created, as hopefully, will be extra-solar planets orbiting them ! Results: We find (pre-main sequence) model-dependent isochronal ages of the Lupus, Chamaeleon and CrA targets to be $9.1 \\pm 2.1$ Myr, $4.5 \\pm 1.6$ Myr and $9.0 \\pm 3.9$ Myr respectively. The majority of the stars have Li I 6707.8A equivalent widths similar to, or above those of, their similar mass Pleiades counterparts, confirming their youthfulness. Most stars are kinematic members, either single or binary, of their regions. We find a mean radial velocity for objects in the Lupus cloud to be ${\\bar {RV}}=+2.6 \\pm 1.8$ km s$^{-1}$, for the Chamaeleon I & II clouds, ${\\bar {RV}}=+12.8 \\pm 3.6$ km s$^{-1}$ whereas for the CrA cloud, we find ${\\bar {RV}}=-1.1 \\pm 0.5$ km s$^{-1}$. All stars are coronally and chromospherically active, exhibiting X-ray and H$\\alpha$ emission levels marginally less,...

  12. An extensive VLT/X-shooter library of photospheric templates of pre-main sequence stars

    Science.gov (United States)

    Manara, C. F.; Frasca, A.; Alcalá, J. M.; Natta, A.; Stelzer, B.; Testi, L.

    2017-09-01

    Context. Studies of the formation and evolution of young stars and their disks rely on knowledge of the stellar parameters of the young stars. The derivation of these parameters is commonly based on comparison with photospheric template spectra. Furthermore, chromospheric emission in young active stars impacts the measurement of mass accretion rates, a key quantity for studying disk evolution. Aims: Here we derive stellar properties of low-mass (M⋆≲ 2 M⊙) pre-main sequence stars without disks, which represent ideal photospheric templates for studies of young stars. We also use these spectra to constrain the impact of chromospheric emission on the measurements of mass accretion rates. The spectra are reduced, flux-calibrated, and corrected for telluric absorption, and are made available to the community. Methods: We derive the spectral type for our targets by analyzing the photospheric molecular features present in their VLT/X-shooter spectra by means of spectral indices and comparison of the relative strength of photospheric absorption features. We also measure effective temperature, gravity, projected rotational velocity, and radial velocity from our spectra by fitting them with synthetic spectra with the ROTFIT tool. The targets have negligible extinction (AVhttp://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/605/A86

  13. Constraints on the height of the inner disk rim in pre-main-sequence stars

    CERN Document Server

    Vinković, Dejan

    2014-01-01

    The structure of inner region of protoplanetary disks around young pre-main-sequence stars is still poorly understood. This part of the disk is shaped by various forces influencing dust and gas dynamics and by dust sublimation, which creates abrupt drops in the dust density. This region also emits a strong near-infrared excess that cannot be explained by classical accretion disk models, which suggests the existence of some unusual dust distribution or disk shape. The most prevalent explanation to date is the puffed-up inner disk rim model, where the disk exhibits an optically thin cavity around the star up to the distance of dust sublimation. The critical parameter in this model is the inner disk rim height $z_{\\rm max}$ relative to the rim's distance from the star $R_{\\rm in}$. Observations often require $z_{\\rm max}/R_{\\rm in}\\gtrsim0.2$ to reproduce the near-infrared excess in the spectra. In this paper we put together a comprehensive list of processes that can shape the inner disk rim and combined them to...

  14. Exploring pre-main-sequence variables of the ONC: the new variables

    Science.gov (United States)

    Parihar, Padmakar; Messina, Sergio; Distefano, Elisa; Shantikumar, N. S.; Medhi, Biman J.

    2009-12-01

    Since 2004, we have been engaged in a long-term observing programme to monitor young stellar objects (YSOs) in the Orion Nebula Cluster (ONC). We have collected about 2000 frames in V, R and I broad-band filters on more than 200 nights distributed over five consecutive observing seasons. The high-quality and time-extended photometric data give us an opportunity to address various phenomena associated with young stars. The prime motivations of this project are (i) to explore various manifestations of stellar magnetic activity in very young low-mass stars, (ii) to search for new pre-main-sequence eclipsing binaries and (iii) to look for any EXor and FUor-like transient activities associated with YSOs. Since this is the first paper on this programme, we give a detailed description of the science drivers, the observation and the data reduction strategies as well. In addition to these, we also present a large number of new periodic variables detected from our first 5 yr of time-series photometric data. Our study reveals that about 72 per cent of classical T Tauri stars (CTTS) in our field of view are periodic, whereas only 32 per cent of weak-lined T Tauri stars (WTTS) are periodic. This indicates that inhomogeneity patterns on the surface of CTTS of the ONC stars are much more stable than on WTTS. From our multiyear monitoring campaign, we found that the photometric surveys based on single season are incapable of identifying all periodic variables. And any study on evolution of angular momentum based on single-season surveys must be carried out with caution.

  15. X-ray Emission Properties of Intermediate-Mass, Pre-Main-Sequence Stars

    Science.gov (United States)

    Povich, Matthew S.; Binder, Breanna; Townsley, Leisa K.; Broos, Patrick S.

    2017-08-01

    Intermediate-mass (2-8 M⊙) main-sequence stars with A to mid-B spectral types occupy an X-ray "desert" of weak intrinsic emission between low- and high-mass stars. Lacking the wind-shock driven emission of massive, O and early B stars or the convectively-driven magnetic reconnection flaring activity of later-type stars, X-ray detections of (non-peculiar) main-sequence AB stars are typically ascribed to the presence of unresolved, lower-mass binary companions. There is mounting evidence, however, that intermediate-mass, pre-main sequence stars (IMPS) with GK spectral types produce intrinsic X-ray emission that rapidly decays with time following the development of a radiative zone as IMPS approach the ZAMS as AB stars. This suggests that X-ray emission from IMPS may be a more luminous analog of the well-studied coronal X-ray emission from lower-mass, T Tauri stars. Statistical studies of young IMPS have been hampered by their scarcety in nearby, unobscured star-forming regions. We present the first results from a spectral-fitting study to measure absorption-corrected X-ray luminosities and plasma temperatures for hundreds of candidate X-ray emitting IMPS found in the MYStIX and MAGiX surveys of massive Galactic star forming regions. Candidate IMPS are placed on the HR diagram via a novel infrared spectral energy distribution modeling technique designed for highly-obscured, young massive star-forming regions. The rapid decay of X-ray emission from these objects has the potential to provide an independent chronometer to constrain star formation rates, and may produce an age-dependent bias in the relationship between the stellar X-ray luminosity function and mass function in distant (>2 kpc) regions observed with relatively shallow X-ray observations.This work is supported by the National Science Foundation under grant CAREER-1454334 and by NASA through Chandra Award 18200040.

  16. The discovery of a low mass, pre-main-sequence stellar association around $\\gamma$ Velorum

    CERN Document Server

    Pozzo, M; Naylor, T; Totten, E J; Harmer, S; Kenyon, M E

    2000-01-01

    We report the serendipitous discovery of a population of low mass, pre-mainsequence stars (PMS) in the direction of the Wolf-Rayet/O-star binary systemgamma^{2} Vel and the Vela OB2 association. We argue that gamma^{2} Vel and thelow mass stars are truly associated, are approximately coeval and that both areat distances between 360-490 pc, disagreeing at the 2 sigma level with therecent Hipparcos parallax of gamma^{2} Vel, but consistent with older distanceestimates. Our results clearly have implications for the physical parameters ofthe gamma^{2} Vel system, but also offer an exciting opportunity to investigatethe influence of high mass stars on the mass function and circumstellar disclifetimes of their lower mass PMS siblings.

  17. Empirical Tests of Pre-Main-Sequence Stellar Evolution Models with Eclipsing Binaries

    CERN Document Server

    Stassun, Keivan G; Torres, Guillermo

    2014-01-01

    We examine the performance of standard PMS stellar evolution models against the accurately measured properties of a benchmark sample of 26 PMS stars in 13 EB systems. We provide a definitive compilation of all fundamental properties for the EBs. We also provide a definitive compilation of the various PMS model sets. In the H-R diagram, the masses inferred for the individual stars by the models are accurate to better than 10% above 1 Msun, but below 1 Msun they are discrepant by 50-100%. We find evidence that the failure of the models to match the data is linked to the triples in the EB sample; at least half of the EBs possess tertiary companions. Excluding the triples, the models reproduce the stellar masses to better than ~10% in the H-R diagram, down to 0.5 Msun, below which the current sample is fully contaminated by tertiaries. We consider several mechanisms by which a tertiary might cause changes in the EB properties and thus corrupt the agreement with stellar model predictions. We show that the energies...

  18. The Gaia-ESO Survey: lithium depletion in the Gamma Velorum cluster and inflated radii in low-mass pre-main-sequence stars

    Science.gov (United States)

    Jeffries, R. D.; Jackson, R. J.; Franciosini, E.; Randich, S.; Barrado, D.; Frasca, A.; Klutsch, A.; Lanzafame, A. C.; Prisinzano, L.; Sacco, G. G.; Gilmore, G.; Vallenari, A.; Alfaro, E. J.; Koposov, S. E.; Pancino, E.; Bayo, A.; Casey, A. R.; Costado, M. T.; Damiani, F.; Hourihane, A.; Lewis, J.; Jofre, P.; Magrini, L.; Monaco, L.; Morbidelli, L.; Worley, C. C.; Zaggia, S.; Zwitter, T.

    2017-01-01

    We show that non-magnetic models for the evolution of pre-main-sequence (PMS) stars cannot simultaneously describe the colour-magnitude diagram (CMD) and the pattern of lithium depletion seen in the cluster of young, low-mass stars surrounding γ2 Velorum. The age of 7.5 ± 1 Myr inferred from the CMD is much younger than that implied by the strong Li depletion seen in the cluster M-dwarfs, and the Li depletion occurs at much redder colours than predicted. The epoch at which a star of a given mass depletes its Li and the surface temperature of that star are both dependent on its radius. We demonstrate that if the low-mass stars have radii ˜10 per cent larger at a given mass and age, then both the CMD and the Li-depletion pattern of the Gamma Velorum cluster are explained at a common age of ≃18-21 Myr. This radius inflation could be produced by some combination of magnetic suppression of convection and extensive cool starspots. Models that incorporate radius inflation suggest that PMS stars, similar to those in the Gamma Velorum cluster, in the range 0.2 30 per cent) than inferred from conventional, non-magnetic models in the Hertzsprung-Russell diagram. Systematic changes of this size may be of great importance in understanding the evolution of young stars, disc lifetimes and the formation of planetary systems.

  19. The Gaia-ESO Survey: Lithium depletion in the Gamma Velorum cluster and inflated radii in low-mass pre-main-sequence stars

    CERN Document Server

    Jeffries, R D; Franciosini, E; Randich, S; Barrado, D; Frasca, A; Klutsch, A; Lanzafame, A C; Prisinzano, L; Sacco, G G; Gilmore, G; Vallenari, A; Alfaro, E J; Koposov, S E; Pancino, E; Bayo, A; Casey, A R; Costado, M T; Damiani, F; Hourihane, A; Lewis, J; Jofre, P; Magrini, L; Monaco, L; Morbidelli, L; Worley, C C; Zaggia, S; Zwitter, T

    2016-01-01

    We show that non-magnetic models for the evolution of pre-main-sequence (PMS) stars *cannot* simultaneously describe the colour-magnitude diagram (CMD) and the pattern of lithium depletion seen in the cluster of young, low-mass stars surrounding $\\gamma^2$ Velorum. The age of 7.5+/-1 Myr inferred from the CMD is much younger than that implied by the strong Li depletion seen in the cluster M-dwarfs and the Li depletion occurs at much redder colours than predicted. The epoch at which a star of a given mass depletes its Li and the surface temperature of that star are both dependent on its radius. We demonstrate that if the low-mass stars have radii ~10 per cent larger at a given mass and age, then both the CMD and Li depletion pattern of the Gamma Vel cluster are explained at a common age of 18-21 Myr. This radius inflation could be produced by some combination of magnetic suppression of convection and extensive cool starspots. Models that incorporate radius inflation suggest that PMS stars similar to those in t...

  20. The Interior Structure Constants as an Age Diagnostic for Low-Mass, Pre-Main Sequence Detached Eclipsing Binary Stars

    CERN Document Server

    Feiden, Gregory A

    2013-01-01

    We propose a novel method for determining the ages of low-mass, pre-main sequence stellar systems using the apsidal motion of low-mass detached eclipsing binaries. The apsidal motion of a binary system with an eccentric orbit provides information regarding the interior structure constants of the individual stars. These constants are related to the normalized stellar interior density distribution and can be extracted from the predictions of stellar evolution models. We demonstrate that low-mass, pre-main sequence stars undergoing radiative core contraction display rapidly changing interior structure constants (greater than 5% per 10 Myr) that, when combined with observational determinations of the interior structure constants (with 5 -- 10% precision), allow for a robust age estimate. This age estimate, unlike those based on surface quantities, is largely insensitive to the surface layer where effects of magnetic activity are likely to be most pronounced. On the main sequence, where age sensitivity is minimal,...

  1. Age-Related Observations of Low Mass Pre-Main and Young Main Sequence Stars (Invited Review)

    CERN Document Server

    Hillenbrand, Lynne A

    2008-01-01

    This overview summarizes the age dating methods available for young sub-solar mass stars. Pre-main sequence age diagnostics include the Hertzsprung-Russell (HR) diagram, spectroscopic surface gravity indicators, and lithium depletion; asteroseismology is also showing recent promise. Near and beyond the zero-age main sequence, rotation period or vsini and activity (coronal and chromospheric) diagnostics along with lithium depletion serve as age proxies. Other authors in this volume present more detail in each of the aforementioned areas. Herein, I focus on pre-main sequence HR diagrams and address the questions: Do empirical young cluster isochrones match theoretical isochrones? Do isochrones predict stellar ages consistent with those derived via other independent techniques? Do the observed apparent luminosity spreads at constant effective temperature correspond to true age spreads? While definitive answers to these questions are not provided, some methods of progression are outlined.

  2. The Effect of Screening Factors and Thermonuclear Reaction Rates in the Pre-main Sequence Evolution of Low Mass Stars

    Indian Academy of Sciences (India)

    İ. Küçük; Ş. Çalışkan

    2010-09-01

    In understanding the nucleosynthesis of the elements in stars, one of the most important quantities is the reaction rate and it must be evaluated in terms of the stellar temperature , and its determination involves the knowledge of the excitation function () of the specific nuclear reaction leading to the final nucleus. In this paper, the effect of thermonuclear reaction rates to the pre-main sequence evolution of low mass stars having masses 0.7, 0.8, 0.9 and 1 M⊙ are studied by using our modified Stellar Evolutionary Program.

  3. A Wide-Field Survey for Transiting Hot Jupiters and Eclipsing Pre-Main-Sequence Binaries in Young Stellar Associations

    CERN Document Server

    Oelkers, Ryan J; Marshall, Jennifer L; DePoy, Darren L; Lambas, Diego G; Colazo, Carlos; Stringer, Katelyn

    2016-01-01

    The past two decades have seen a significant advancement in the detection, classification and understanding of exoplanets and binaries. This is due, in large part, to the increase in use of small-aperture telescopes (< 20 cm) to survey large areas of the sky to milli-mag precision with rapid cadence. The vast majority of the planetary and binary systems studied to date consist of main-sequence or evolved objects, leading to a dearth of knowledge of properties at early times (< 50 Myr). Only a dozen binaries and one candidate transiting Hot Jupiter are known among pre-main sequence objects, yet these are the systems that can provide the best constraints on stellar formation and planetary migration models. The deficiency in the number of well-characterized systems is driven by the inherent and aperiodic variability found in pre-main-sequence objects, which can mask and mimic eclipse signals. Hence, a dramatic increase in the number of young systems with high-quality observations is highly desirable to gui...

  4. A statistical analysis of X-ray variability in pre-main sequence objects of the Taurus Molecular Cloud

    CERN Document Server

    Stelzer, B; Briggs, K; Micela, G; Scelsi, L; Audard, M; Pillitteri, I; Güdel, M

    2006-01-01

    This work is part of a systematic X-ray survey of the Taurus star forming complex with XMM-Newton. We study the time series of all X-ray sources associated with Taurus members, to statistically characterize their X-ray variability, and compare the results to those for pre-main sequence stars in the Orion Nebula Cluster and to expectations arising from a model where all the X-ray emission is the result of a large number of stochastically occurring flares. We find that roughly half of the detected X-ray sources show variability above our sensitivity limit, and in ~ 26 % of the cases this variability is recognized as flares. Variability is more frequently detected at hard than at soft energies. The variability statistics of cTTS and wTTS are undistinguishable, suggesting a common (coronal) origin for their X-ray emission. We have for the first time applied a rigorous maximum likelihood method in the analysis of the number distribution of flare energies on pre-main sequence stars. In its differential form this di...

  5. The Mdot - M* relation of pre-main sequence stars: a consequence of X-ray driven disc evolution

    CERN Document Server

    Ercolano, B; Owen, J E; Rosotti, G; Manara, C F

    2013-01-01

    We analyse current measurements of accretion rates onto pre-main sequence stars as a function of stellar mass, and conclude that the steep dependance of accretion rates on stellar mass is real and not driven by selection/detection threshold, as has been previously feared. These conclusions are reached by means of statistical tests including a survival analysis which can account for upper limits. The power-law slope of the Mdot-M* relation is found to be in the range of 1.6-1.9 for young stars with masses lower than 1 Msun. The measured slopes and distributions can be easily reproduced by means of a simple disc model which includes viscous accretion and X-ray photoevaporation. We conclude that the Mdot-M* relation in pre-main sequence stars bears the signature of disc dispersal by X-ray photoevaporation, suggesting that the relation is a straight- forward consequence of disc physics rather than an imprint of initial conditions.

  6. Magnetic fields and differential rotation on the pre-main sequence III: The early-G star HD 106506

    CERN Document Server

    Waite, I A; Carter, B D; Hart, R; Donati, J -F; Vélez, J C Ramírez; Semel, M; Dunstone, N

    2011-01-01

    We present photometry and spectropolarimetry of the pre-main sequence star HD 106506. A photometric rotational period of ~1.416 +/- 0.133 days has been derived using observations at Mount Kent Observatory (MKO). Spectropolarimetric data taken at the 3.9-m Anglo-Australian Telescope (AAT) were used to derive spot occupancy and magnetic maps of the star through the technique of Zeeman Doppler imaging (ZDI). The resulting brightness maps indicate that HD 106506 displays photospheric spots at all latitudes including a predominant polar spot. Azimuthal and radial magnetic images of this star have been derived, and a significant azimuthal magnetic field is indicated, in line with other active young stars. A solar-like differential rotation law was incorporated into the imaging process. Using Stokes I information the equatorial rotation rate, $\\Omega_{eq}$, was found to be 4.54 +/- 0.01 rad/d, with a photospheric shear $\\delta\\Omega$ of $0.21_{-0.03}^{+0.02}$ rad/d. This equates to an equatorial rotation period of ~...

  7. The Solar Neighborhood. XXVI. AP Col: The Closest (8.4 pc) Pre-Main-Sequence Star

    CERN Document Server

    Riedel, Adric R; Henry, Todd J; Melis, Carl; Jao, Wei-Chun; Subasavage, John P; 10.1088/0004-6256/142/4/104

    2011-01-01

    We present the results of a multi-technique investigation of the M4.5Ve flare star AP Col, which we discover to be the nearest pre-main-sequence star. These include astrometric data from the CTIO 0.9m, from which we derive a proper motion of 342.0+/-0.5 mas yr^-1, a trigonometric parallax of 119.21+/-0.98 mas (8.39+/-0.07 pc), and photometry and photometric variability at optical wavelengths. We also provide spectroscopic data, including radial velocity (22.4+/-0.3 km s^-1), lithium Equivalent Width (EW) (0.28+/-0.02 A), H-alpha EW (-6.0 to -35 A), {\\it vsini} (11+/-1 km s^-1), and gravity indicators from the Siding Spring 2.3-m WiFeS, Lick 3-m Hamilton echelle, and Keck-I HIRES echelle spectrographs. The combined observations demonstrate that AP Col is the closer of only two known systems within 10 pc of the Sun younger than 100 Myr. Given its space motion and apparent age of 12-50 Myr, AP Col is likely a member of the recently proposed ~40 Myr old Argus/IC 2391 association.

  8. Dust disks around old Pre Main-Sequence stars HST\\/NICMOS2 scattered light images and modeling

    CERN Document Server

    Augereau, J C; Mouillet, D; Ménard, F

    2000-01-01

    We present recent near-infrared detections of circumstellar disks around the two old PMS Herbig stars HD 141569 and HD 100546 obtained with the HST/NICMOS2 camera. They reveal extended structures larger than 350-400 AU in radius. While the HD 100546 disk appears as a continuous disk down to 40 AU, the HD 141569 environment seems more complex, splitted at least into two dust populations. As a convincing example, the full modeling of the disk surrounding HR 4796, another old PMS star, is detailed and confronted with more recent observations.

  9. Long-term BVRI light curves of 5 pre-main sequence stars in the field of "Gulf of Mexico"

    OpenAIRE

    Ibryamov, Sunay I.; Semkov, Evgeni H.; Peneva, Stoyanka P.

    2014-01-01

    We present new data from BVRI photometric observations of five PMS stars during the period from April 2013 to July 2014. The stars are located in the field of NGC 7000/IC 5070 ("Gulf of Mexico") - a region with active star formation. The presented paper is a continuation of our long-term photometric investigations of the young stellar objects in this region. The long-term multicolor photometric observations of PMS stars are very important for their exact classification. Our results show that ...

  10. Analysis of flares in the chromosphere and corona of main- and pre-main-sequence M-type stars

    Science.gov (United States)

    Crespo-Chacón, I.

    2015-11-01

    This Ph.D. Thesis revolves around flares on main- and pre-main-sequence M-type stars. We use observations in different wavelength ranges with the aim of analysing the effects of flares at different layers of stellar atmospheres. In particular, optical and X-ray observations are used so that we can study how flares affect, respectively, the chromosphere and the corona of stars. In the optical range we carry out a high temporal resolution spectroscopic monitoring of UV Ceti-type stars aimed at detecting non-white-light flares (the most typical kind of solar flares) in stars other than the Sun. With these data we confirm that non-white-light flares are a frequent phenomenon in UV Ceti-type stars, as observed in the Sun. We study and interpret the behaviour of different chromospheric lines during the flares detected on AD Leo. By using a simplified slab model of flares (Jevremović et al. 1998), we are able to determine the physical parameters of the chromospheric flaring plasma (electron density and electron temperature), the temperature of the underlying source, and the surface area covered by the flaring plasma. We also search for possible relationships between the physical parameters of the flaring plasma and other properties such as the flare duration, area, maximum flux and released energy. This work considerably extends the existing sample of stellar flares analysed with good quality spectroscopy in the optical range. In X-rays we take advantage of the great sensitivity, wide energy range, high energy resolution, and continuous time coverage of the EPIC detectors - on-board the XMMNewton satellite - in order to perform time-resolved spectral analysis of coronal flares. In particular, in the UV Ceti-type star CC Eri we study two flares that are weaker than those typically reported in the literature (allowing us to speculate about the role of flares as heating agents of stellar atmospheres); while in the pre-main-sequence M-type star TWA 11B (with no signatures of

  11. The pre-main-sequence star V1184 Tauri (CB 34V) at the end of prolonged eclipse

    Science.gov (United States)

    Semkov, E. H.; Peneva, S. P.; Ibryamov, S. I.

    2015-10-01

    Aims: V1184 Tau (CB 34V) lies in the field of the Bok globule CB 34 and was discovered as a large amplitude variable in 1993. According to the first hypothesis of the variability of the star, it is a FU Orionis candidate erupted between 1951 and 1993. During subsequent observations, the star manifests large amplitude variability interpreted as obscuration from circumstellar clouds of dust. We included V1184 Tau (CB 34V) in our target list of highly variable pre-main-sequence stars to determine the reasons for the variations in the brightness of this object. Methods: Data from BVRI photometric observations of the young stellar object V1184 Tau, obtained in the period 2008-2015, are presented in the paper. These data are a continuation of our optical photometric monitoring of the star began in 2000 and continuing to date. The photometric observations of V1184 Tau were performed in two observatories with two medium-sized and two small telescopes. Results: Our results indicate that during periods of maximum light the star shows characteristics typical of T Tauri stars. During the observed deep minimum in brightness, however, V1184 Tau is rather similar to UX Orionis objects. The deep drop in brightness began in 2003 ended in 2015 as the star has returned to maximum light. The light curve during the drop is obviously asymmetric as the decrease in brightness lasts two times longer than the rise. The observed colour reverse on the colour-magnitude diagrams is also confirmation of obscuration from circumstellar clouds of dust as a reason for the large amplitude variability in the brightness. Appendix A is available in electronic form at http://www.aanda.org

  12. An IUE Atlas of Pre-Main-Sequence Stars. II. Far-Ultraviolet Accretion Diagnostics in T Tauri Stars

    Science.gov (United States)

    Johns-Krull, Christopher M.; Valenti, Jeff A.; Linsky, Jeffrey L.

    2000-08-01

    We use our ultraviolet (UV) atlas of pre-main-sequence stars constructed from all useful, short-wavelength, low-resolution spectra in the International Ultraviolet Explorer (IUE) satellite Final Archive to analyze the short-wavelength UV properties of 49 T Tauri stars (TTSs). We compare the line and continuum fluxes in these TTSs with each other and with previously published parameters of these systems, including rotation rate, infrared excess, and mass accretion rate. The short-wavelength continuum in the classical TTSs (CTTSs) appears to originate in a ~10,000 K optically thick plasma, while in the naked TTSs (NTTSs-stars without dusty disks) the continuum appears to originate in the stellar atmosphere. We show that all of the TTSs in our sample lie in the regime of ``saturated'' magnetic activity due to their small Rossby numbers. However, while some of the TTSs show emission line surface fluxes consistent with this saturation level, many CTTSs show significantly stronger emission than predicted by saturation. In these stars, the emission line luminosity in the high ionization lines present in the spectrum between 1200 and 2000 Å correlates well with the mass accretion rate. Therefore, we conclude that the bulk of the short-wavelength emission seen in CTTSs results from accretion related processes and not from dynamo-driven magnetic activity. Using CTTSs with known mass accretion rates, we calibrate the relationship between M and LC IV to derive the mass accretion rate for some CTTSs which for various reasons have never had their mass accretion rates measured. Finally, several of the CTTSs show strong emission from molecular hydrogen. While emission from H2 cannot form in gas at a temperature of ~105 K, the strength of the molecular hydrogen emission is nevertheless well correlated with all the other emissions displayed in the IUE short-wavelength bandpass. This suggests that the H2 emission is in fact fluorescent emission pumped by the emission (likely Ly

  13. Long-term BVRI light curves of 5 pre-main sequence stars in the field of "Gulf of Mexico"

    CERN Document Server

    Ibryamov, Sunay I; Peneva, Stoyanka P

    2014-01-01

    We present new data from BVRI photometric observations of five PMS stars during the period from April 2013 to July 2014. The stars are located in the field of NGC 7000/IC 5070 ("Gulf of Mexico") - a region with active star formation. The presented paper is a continuation of our long-term photometric investigations of the young stellar objects in this region. The long-term multicolor photometric observations of PMS stars are very important for their exact classification. Our results show that the studied stars exhibit different types of photometric variability in all bands. We tried to classify them using our data from the long-term photometry and data published by other authors.

  14. The fate of the pre-main sequence-rich clusters Collinder197 and vdB92: dissolution?

    CERN Document Server

    Bonatto, Charles

    2010-01-01

    We investigate the nature and possible evolution of the young Galactic star clusters Collinder 197 (Cr 197) and vdB 92. The colour-magnitude diagrams (CMDs) are basically characterised by a poorly-populated MS and a dominant fraction ($\\ga75%$) of PMS stars, and the combined MS and PMS CMD morphology in both clusters consistently constrains the age to within $5\\pm4$ Myr, with a $\\sim10$ Myr spread in the star formation process. The MS$ + $PMS stellar masses are $\\approx660^{+102}_{-59} \\ms$ (Cr 197) and $\\approx750^{+101}_{-51} \\ms$ (vdB 92). Cr 197 and vdB 92 appear to be abnormally large, when compared to clusters within the same age range. They have irregular stellar radial density distributions (RDPs) with a marked excess in the innermost region, a feature that, at less than 10 Myr, is more likely related to the star formation and/or molecular cloud fragmentation than to age-dependent dynamical effects. The velocity dispersion of both clusters, derived from proper motions, is in the range $\\sim15 - 22 \\km...

  15. Effect of accretion on the pre-main-sequence evolution of low-mass stars and brown dwarfs

    Science.gov (United States)

    Vorobyov, Eduard I.; Elbakyan, Vardan; Hosokawa, Takashi; Sakurai, Yuya; Guedel, Manuel; Yorke, Harold

    2017-09-01

    Aims: The pre-main-sequence evolution of low-mass stars and brown dwarfs is studied numerically starting from the formation of a protostellar or proto-brown dwarf seed and taking into account the mass accretion onto the central object during the initial several Myr of evolution. Methods: The stellar evolution was computed using the STELLAR evolution code with recent modifications. The mass accretion rates were taken from numerical hydrodynamics models by computing the circumstellar disk evolution starting from the gravitational collapse of prestellar cloud cores of various mass and angular momentum. The resulting stellar evolution tracks were compared with the isochrones and isomasses calculated using non-accreting models. Results: We find that mass accretion in the initial several Myr of protostellar evolution can have a strong effect on the subsequent evolution of young stars and brown dwarfs. The disagreement between accreting and non-accreting models in terms of the total stellar luminosity L∗, stellar radius R∗, and effective temperature Teff depends on the thermal efficiency of accretion, that is, on the fraction of accretion energy that is absorbed by the central object. The largest mismatch is found for the cold accretion case, in which essentially all accretion energy is radiated away. The relative deviations in L∗ and R∗ in this case can reach 50% for objects 1.0 Myr old, and they remain notable even for objects 10 Myr old. In the hot and hybrid accretion cases, in which a constant fraction of accretion energy is absorbed, the disagreement between accreting and non-accreting models becomes less pronounced, but still remains notable for objects 1.0 Myr old. These disagreements may lead to an incorrect age estimate for objects of (sub-)solar mass when using the isochrones that are based on non-accreting models, as has also been noted previously. We find that objects with strong luminosity bursts exhibit notable excursions in the L∗-Teff diagram

  16. Extended Magnetospheres in Pre-main-sequence Evolution: From T Tauri Stars to the Brown Dwarf Limit

    Science.gov (United States)

    Gómez de Castro, Ana I.; Marcos-Arenal, Pablo

    2012-04-01

    Low-mass pre-main-sequence stars, i.e., T Tauri stars (TTSs), strongly radiate at high energies, from X-rays to the ultraviolet (UV). This excess radiation with respect to main-sequence cool stars (MSCSs) is associated with the accretion process, i.e., it is produced in the extended magnetospheres, in the accretion shocks on the stellar surface, and in the outflows. Although evidence of accretion shocks and outflow contribution to the high-energy excess have been recently addressed, there is not an updated revision of the magnetospheric contribution. This article addresses this issue. The UV observations of the TTSs in the well-known Taurus region have been analyzed together with the XMM-Newton observations compiled in the XEST survey. For the first time the high sensitivity of the Hubble Space Telescope UV instrumentation has allowed measurement of the UV line fluxes of TTSs to M8 type. UV- and X-ray-normalized fluxes have been determined to study the extent and properties of the TTS magnetospheres as a class. They have been compared with the atmospheres of the MSCSs. The main results from this analysis are (1) the normalized fluxes of all the tracers are correlated; this correlation is independent of the broad mass range and the hardness of the X-ray radiation field; (2) the TTS correlations are different than the MSCS correlations; (3) there is a very significant excess emission in O I in the TTSs compared with MSCSs that seems to be caused by recombination radiation from the disk atmosphere after photoionization by extreme UV radiation; the Fe II/Mg II recombination continuum has also been detected in several TTSs and most prominently in AA Tau; and (4) the normalized flux of the UV tracers anticorrelates with the strength of the X-ray flux, i.e., the stronger the X-ray surface flux is, the weaker the observed UV flux. This last behavior is counterintuitive within the framework of stellar dynamo theory and suggests that UV emission can be produced in the

  17. A Critical Assessment of Ages Derived Using Pre-Main-Sequence Isochrones in Colour-Magnitude Diagrams

    Science.gov (United States)

    Bell, Cameron P. M.

    2012-11-01

    In this thesis a critical assessment of the ages derived using theoretical pre-main-sequence (pre-MS) stellar evolutionary models is presented by comparing the predictions to the low-mass pre-MS population of 14 young star-forming regions (SFRs) in colour-magnitude diagrams (CMDs). Deriving pre-MS ages requires precise distances and estimates of the reddening. Therefore, the main-sequence (MS) members of the SFRs have been used to derive a self-consistent set of statistically robust ages, distances and reddenings with associated uncertainties using a maximum-likelihood fitting statistic and MS evolutionary models. A photometric method for de-reddening individual stars - known as the Q-method - in regions where the extinction is spatially variable has been updated and is presented. The effects of both the model dependency and the SFR composition on these derived parameters are also discussed. The problem of calibrating photometric observations of red pre-MS stars is examined and it is shown that using observations of MS stars to transform the data into a standard photometric system can introduce significant errors in the position of the pre-MS locus in CMD space. Hence, it is crucial that precise photometric studies - especially of pre-MS objects - be carried out in the natural photometric system of the observations. This therefore requires a robust model of the system responses for the instrument used, and thus the calculated responses for the Wide-Field Camera on the Isaac Newton Telescope are presented. These system responses have been tested using standard star observations and have been shown to be a good representation of the photometric system. A benchmark test for the pre-MS evolutionary models is performed by comparing them to a set of well-calibrated CMDs of the Pleiades in the wavelength regime 0.4-2.5 μm. The masses predicted by these models are also tested against dynamical masses using a sample of MS binaries by calculating the system magnitude in a

  18. Dynamo action and magnetic activity during the pre-main sequence: Influence of rotation and structural changes

    Science.gov (United States)

    Emeriau-Viard, Constance; Brun, Allan Sacha

    2017-10-01

    During the PMS, structure and rotation rate of stars evolve significantly. We wish to assess the consequences of these drastic changes on stellar dynamo, internal magnetic field topology and activity level by mean of HPC simulations with the ASH code. To answer this question, we develop 3D MHD simulations that represent specific stages of stellar evolution along the PMS. We choose five different models characterized by the radius of their radiative zone following an evolutionary track, from 1 Myr to 50 Myr, computed by a 1D stellar evolution code. We introduce a seed magnetic field in the youngest model and then we spread it through all simulations. First of all, we study the consequences that the increase of rotation rate and the change of geometry of the convective zone have on the dynamo field that exists in the convective envelop. The magnetic energy increases, the topology of the magnetic field becomes more complex and the axisymmetric magnetic field becomes less predominant as the star ages. The computation of the fully convective MHD model shows that a strong dynamo develops with a ratio of magnetic to kinetic energy reaching equipartition and even super-equipartition states in the faster rotating cases. Magnetic fields resulting from our MHD simulations possess a mixed poloidal-toroidal topology with no obvious dominant component. We also study the relaxation of the vestige dynamo magnetic field within the radiative core and found that it satisfies stability criteria. Hence it does not experience a global reconfiguration and instead slowly relaxes by retaining its mixed poloidal-toroidal topology.

  19. The Gaia-ESO Survey: pre-main-sequence stars in the young open cluster NGC 3293

    Science.gov (United States)

    Delgado, A. J.; Sampedro, L.; Alfaro, E. J.; Costado, M. T.; Yun, J. L.; Frasca, A.; Lanzafame, A. C.; Drew, J. E.; Eislöffel, J.; Blomme, R.; Morel, T.; Lobel, A.; Semaan, T.; Randich, S.; Jeffries, R. D.; Micela, G.; Vallenari, A.; Kalari, V.; Gilmore, G.; Flaccomio, E.; Carraro, G.; Lardo, C.; Monaco, L.; Prisinzano, L.; Sousa, S. G.; Morbidelli, L.; Lewis, J.; Koposov, S.; Hourihane, A.; Worley, C.; Casey, A.; Franciosini, E.; Sacco, G.; Magrini, L.

    2016-08-01

    The young open cluster NGC3293 is included in the observing program of the Gaia-ESO survey (GES). The radial velocity values provided have been used to assign cluster membership probabilities by means of a single-variable parametric analysis. These membership probabilities are compared to the results of the photometric membership assignment of NGC3293, based on UBVRI photometry. The agreement of the photometric and kinematic member samples amounts to 65 per cent, and could increase to 70 per cent as suggested by the analysis of the differences between both samples. A number of photometric PMS candidate members of spectral type F are found, which are confirmed by the results from VPHAS photometry and SED fitting for the stars in common with VPHAS and GES data sets. Excesses at mid- and near-infrared wavelengths, and signs of Hα emission, are investigated for them. Marginal presence of Hα emission or infilling is detected for the candidate members. Several of them exhibit moderate signs of U excess and weak excesses at mid-IR wavelengths. We suggest that these features originate from accretion discs in their last stages of evolution.

  20. MML 53: a new low-mass, pre-main sequence eclipsing binary in the Upper Centarus-Lupus Region discovered by SuperWASP

    CERN Document Server

    Hebb, L; Aigrain, S; Collier-Cameron, A; Hodgkin, S T; Irwin, J M; Maxted, P F L; Pollacco, D; Street, R A; Wilson, D M; Stassun, K G

    2010-01-01

    We announce the discovery of a new low-mass, pre-main sequence eclipsing binary, MML 53. Previous observations of MML 53 found it to be a pre-main sequence spectroscopic multiple associated with the 15-22 Myr Upper Centaurus Lupus cluster. We identify the object as an eclipsing binary for the first time through the analysis of multiple seasons of time series photometry from the SuperWASP transiting planet survey. Re-analysis of a single archive spectrum shows MML 53 to be a spatially unresolved triple system of young stars which all exhibit significant lithium absorption. Two of the components comprise an eclipsing binary with period, P = 2.097891(6) +- 0.000005 and mass ratio, q~0.8. Here, we present the analysis of the discovery data.

  1. Pms2 suppresses large expansions of the (GAA·TTCn sequence in neuronal tissues.

    Directory of Open Access Journals (Sweden)

    Rebecka L Bourn

    Full Text Available Expanded trinucleotide repeat sequences are the cause of several inherited neurodegenerative diseases. Disease pathogenesis is correlated with several features of somatic instability of these sequences, including further large expansions in postmitotic tissues. The presence of somatic expansions in postmitotic tissues is consistent with DNA repair being a major determinant of somatic instability. Indeed, proteins in the mismatch repair (MMR pathway are required for instability of the expanded (CAG·CTG(n sequence, likely via recognition of intrastrand hairpins by MutSβ. It is not clear if or how MMR would affect instability of disease-causing expanded trinucleotide repeat sequences that adopt secondary structures other than hairpins, such as the triplex/R-loop forming (GAA·TTC(n sequence that causes Friedreich ataxia. We analyzed somatic instability in transgenic mice that carry an expanded (GAA·TTC(n sequence in the context of the human FXN locus and lack the individual MMR proteins Msh2, Msh6 or Pms2. The absence of Msh2 or Msh6 resulted in a dramatic reduction in somatic mutations, indicating that mammalian MMR promotes instability of the (GAA·TTC(n sequence via MutSα. The absence of Pms2 resulted in increased accumulation of large expansions in the nervous system (cerebellum, cerebrum, and dorsal root ganglia but not in non-neuronal tissues (heart and kidney, without affecting the prevalence of contractions. Pms2 suppressed large expansions specifically in tissues showing MutSα-dependent somatic instability, suggesting that they may act on the same lesion or structure associated with the expanded (GAA·TTC(n sequence. We conclude that Pms2 specifically suppresses large expansions of a pathogenic trinucleotide repeat sequence in neuronal tissues, possibly acting independently of the canonical MMR pathway.

  2. Rapid genome evolution in Pms1 region of rice revealed by comparative sequence analysis

    Institute of Scientific and Technical Information of China (English)

    YU JinSheng; FAN YouRong; LIU Nan; SHAN Yan; LI XiangHua; ZHANG QiFa

    2007-01-01

    Pms1, a locus for photoperiod sensitive genic male sterility in rice, was identified and mapped to chromosome 7 in previous studies. Here we report an effort to identify the candidate genes for Pms1 by comparative sequencing of BAC clones from two cultivars Minghui 63 and Nongken 58, the parents for the initial mapping population. Annotation and comparison of the sequences of the two clones resulted in a total of five potential candidates which should be functionally tested. We also conducted comparative analysis of sequences of these two cultivars with two other cultivars, Nipponbare and 93-11,for which sequence data were available in public databases. The analysis revealed large differences in sequence composition among the four genotypes in the Pms1 region primarily due to retroelement activity leading to rapid recent growth and divergence of the genomes. High levels of polymorphism in the forms of indels and SNPs were found both in intra- and inter-subspecific comparisons. Dating analysis using LTRs of the retroelements in this region showed that the substitution rate of LTRs was much higher than reported in the literature. The results provided strong evidence for rapid genomic evolution of this region as a consequence of natural and artificial selection.

  3. Investigation of the magnetic field characteristics of Herbig Ae/Be stars: Discovery of the pre-main sequence progenitors of the magnetic Ap/Bp stars

    CERN Document Server

    Wade, G A; Bagnulo, S; Landstreet, J D; Mason, E; Silvester, J; Alecian, E; Böhm, T; Bouret, J C; Catala, C; Donati, J F; Folsom, C; Bale, K

    2006-01-01

    We are investigating the magnetic characteristics of pre-main sequence Herbig Ae/Be stars, with the aim of (1) understanding the origin and evolution of magnetism in intermediate-mass stars, and (2) exploring the influence of magnetic fields on accretion, rotation and mass-loss at the early stages of evolution of A, B and O stars. We have begun by conducting 2 large surveys of Herbig Ae/Be stars, searching for direct evidence of photospheric magnetic fields via the longitudinal Zeeman effect. From observations obtained using FORS1 at the ESO-VLT and ESPaDOnS at the Canada-France-Hawaii Telescope, we report the confirmed detection of magnetic fields in 4 pre-main sequence A- and B-type stars, and the apparent (but as yet unconfirmed) detection of fields in 2 other such stars. We do not confirm the detection of magnetic fields in several stars reported by other authors to be magnetic: HD 139614, HD 144432 or HD 31649. One of the most evolved stars in the detected sample, HD 72106A, shows clear evidence of stron...

  4. Magnetic fields and differential rotation on the pre-main sequence I: The early-G star HD 141943 - brightness and magnetic topologies

    CERN Document Server

    Marsden, S C; Vélez, J C Ramírez; Alecian, E; Brown, C J; Carter, B D; Donati, J F; Dunstone, N; Hart, R; Semel, M; Waite, I A

    2011-01-01

    Spectroscopic and spectropolarimetric observations of the pre-main sequence early-G star HD 141943 were obtained at four observing epochs (in 2006, 2007, 2009 and 2010). The observations were undertaken at the 3.9-m Anglo-Australian Telescope using the UCLES echelle spectrograph and the SEMPOL spectropolarimeter visitor instrument. Brightness and surface magnetic field topologies were reconstructed for the star using the technique of least-squares deconvolution to increase the signal-to-noise of the data. The reconstructed brightness maps show that HD 141943 had a weak polar spot and a significant amount of low latitude features, with little change in the latitude distribution of the spots over the 4 years of observations. The surface magnetic field was reconstructed at three of the epochs from a high order (l <= 30) spherical harmonic expansion of the spectropolarimetric observations. The reconstructed magnetic topologies show that in 2007 and 2010 the surface magnetic field was reasonably balanced betwee...

  5. Mid-IR spectra of Pre-Main Sequence Herbig stars: an explanation for the non-detections of water lines

    CERN Document Server

    Antonellini, S; Lahuis, F; Woitke, P; Thi, W -F; Meijerink, R; Aresu, G; Spaans, M; Güdel, M; Liebhart, A

    2016-01-01

    The mid-IR detection rate of water lines in disks around Herbig stars disks is about 5\\%, while it is around 50\\% for disks around TTauri stars. The reason for this is still unclear. In this study, we want to find an explanation for the different detection rates between low mass and high mass pre-main-sequence stars (PMSs) in the mid-IR regime. We run disk models with stellar parameters adjusted to spectral types B9 through M2, using the radiation thermo-chemical disk modeling code ProDiMo. We produce convolved spectra at the resolution of Spitzer IRS, JWST MIRI and VLT VISIR spectrographs. We apply random noise derived from typical Spitzer spectra for a direct comparison with observations. The strength of the mid-IR water lines correlates directly with the luminosity of the central star. We explored a small parameter space around a standard disk model, considering dust-to-gas mass ratio, disk gas mass, mixing coefficient for dust settling, flaring index, dust maximum size and size power law distribution inde...

  6. Planetary Construction Zones in Occultation: Eclipses by Circumsecondary and Circumplanetary Disks and a Candidate Eclipse of a Pre-Main Sequence Star in Sco-Cen

    CERN Document Server

    Mamajek, Eric E; Pecaut, Mark; Moolekamp, Fred; Scott, Erin L; Kenworthy, Matthew; Cameron, Andrew Collier; Parley, Neil

    2011-01-01

    The large relative sizes of circumstellar and circumplanetary disks imply that they might be seen in eclipse in stellar light curves. We present photometric and spectroscopic data for a pre-main sequence K5 star (1SWASP J140747.93-394542.6 = ASAS J140748-3945.7), a newly discovered ~0.9 Msun member of the ~16 Myr-old Upper Centaurus-Lupus subgroup of Sco-Cen at a distance of 128+-13 pc. This star exhibited a remarkably long, deep, and complex eclipse event centered on 29 April 2007 (as discovered in SuperWASP photometry, and with portions of the dimming confirmed by ASAS data). At least 5 multi-day dimming events of >0.5 mag are identified, with a >3.3 mag deep eclipse bracketed by two pairs of ~1 mag eclipses symmetrically occurring +-12 days and +-26 days before and after. Hence, significant dimming of the star was taking place on and off over at least a ~54 day period in 2007, and a strong >1 mag dimming event occurring over a ~12 day span. We place a firm lower limit on the period of 850 days (i.e. the o...

  7. XMM-Newton monitoring of the close pre-main-sequence binary AK Sco. Evidence of tide driven filling of the inner gap in the circumbinary disk

    CERN Document Server

    de Castro, Ana I Gomez; Talavera, Antonio; Sytov, A Yu; Bisikalo, D

    2013-01-01

    AK~Sco stands out among pre-main sequence binaries because of its prominent ultraviolet excess, the high eccentricity of its orbit and the strong tides driven by it. AK Sco consists of two F5 type stars that get as close as 11R$_*$ at periastron passage. The presence of a dense ($n_e \\sim 10^{11}$~cm$^{-3}$) extended envelope has been unveiled recently. In this article, we report the results from a XMM-Newton based monitoring of the system. We show that at periastron, X-ray and UV fluxes are enhanced by a factor of $\\sim 3$ with respect to the apastron values. The X-ray radiation is produced in an optically thin plasma with T$\\sim 6.4\\times 10^{6}$ K and it is found that the N$_H$ column density rises from 0.35$\\times 10^{21}$~cm$^{-2}$ at periastron to 1.11$\\times 10^{21}$~cm$^{-2}$ at apastron, in good agreement with previous polarimetric observations. The UV emission detected in the Optical Monitor band seems to be caused by the reprocessing of the high energy magnetospheric radiation on the circumstellar ...

  8. The multipolar magnetic fields of accreting pre-main-sequence stars: B at the inner disk, B along the accretion flow, and B at the accretion shock

    CERN Document Server

    Gregory, Scott G; Hussain, Gaitee A J

    2016-01-01

    Zeeman-Doppler imaging studies have revealed the complexity of the large-scale magnetic fields of accreting pre-main-sequence stars. All have multipolar magnetic fields with the octupole component being the dominant field mode for many of the stars studied thusfar. Young accreting stars with fully convective interiors often feature simple axisymmetric magnetic fields with dipole components of order a kilo-Gauss (at least those of mass $\\gtrsim0.5\\,{\\rm M}_\\odot$), while those with substantially radiative interiors host more complex non-axisymmetric magnetic fields with dipole components of order a few 0.1 kilo-Gauss. Here, via several simple examples, we demonstrate that i). in most cases, the dipole component alone can be used to estimate the disk truncation radius (but little else); ii) due the presence of higher order magnetic field components, the field strength in the accretion spots is far in excess of that expected if a pure dipole magnetic field is assumed. (Fields of $\\sim$6$\\,{\\rm kG}$ have been mea...

  9. CoRoT 223992193: A new, low-mass, pre-main sequence eclipsing binary with evidence of a circumbinary disk

    CERN Document Server

    Gillen, Edward; McQuillan, Amy; Bouvier, Jerome; Hodgkin, Simon; Alencar, Silvia H P; Terquem, Caroline; Southworth, John; Gibson, Neale P; Cody, Ann Marie; Lendl, Monika; Morales-Calderón, Maria; Favata, Fabio; Stauffer, John; Micela, Giuseppina

    2013-01-01

    We present the discovery of CoRoT 223992193, a double-lined, detached eclipsing binary, comprising two pre-main sequence M dwarfs, discovered by the CoRoT space mission during a 23-day observation of the 3 Myr old NGC 2264 star-forming region. Using multi-epoch optical and near-IR follow-up spectroscopy with FLAMES on the Very Large Telescope and ISIS on the William Herschel Telescope we obtain a full orbital solution and derive the fundamental parameters of both stars by modelling the light curve and radial velocity data. The orbit is circular and has a period of $3.8745745 \\pm 0.0000014$ days. The masses and radii of the two stars are $0.67 \\pm 0.01$ and $0.495 \\pm 0.007$ $M_{\\odot}$ and $1.30 \\pm 0.04$ and $1.11 ~^{+0.04}_{-0.05}$ $R_{\\odot}$, respectively. This system is a useful test of evolutionary models of young low-mass stars, as it lies in a region of parameter space where observational constraints are scarce; comparison with these models indicates an apparent age of $\\sim$3.5-6 Myr. The systemic ve...

  10. The Multiple Young Stellar Objects of HBC 515: An X-ray and Millimeter-wave Imaging Study in (Pre-main Sequence) Diversity

    CERN Document Server

    Principe, D A; Kastner, J H; Wilner, D; Stelzer, B; Micela, G

    2016-01-01

    We present Chandra X-ray Observatory and Submillimeter Array (SMA) imaging of HBC 515, a system consisting of multiple young stellar objects (YSOs). The five members of HBC 515 represent a remarkably diverse array of YSOs, ranging from the low-mass Class I/II protostar HBC 515B, through Class II and transition disk objects (HBC 515D and C, respectively), to the "diskless", intermediate- mass, pre-main sequence binary HBC 515A. Our Chandra/ACIS imaging establishes that all five components are X-ray sources, with HBC 515A - a subarcsecond-separation binary that is partially resolved by Chandra - being the dominant X-ray source. We detect an X-ray flare associated with HBC 515B. In the SMA imaging, HBC 515B is detected as a strong 1.3 mm continuum emission source; a second, weaker mm continuum source is coincident with the position of the transition disk object HBC 515C. These results strongly support the protostellar nature of HBC 515B, and firmly establish HBC 515A as a member of the rare class of relatively m...

  11. CoRoT 223992193: Investigating the variability in a low-mass, pre-main sequence eclipsing binary with evidence of a circumbinary disk

    CERN Document Server

    Gillen, Edward; Terquem, Caroline; Bouvier, Jerome; Alencar, Silvia H P; Gandolfi, Davide; Stauffer, John; Cody, Ann Marie; Venuti, Laura; Almeida, Pedro Viana; Micela, Giuseppina; Favata, Fabio; Deeg, Hans J

    2016-01-01

    CoRoT 223992193 is the only known low-mass, pre-main sequence eclipsing binary that shows evidence of a circumbinary disk. The system displays complex photometric and spectroscopic variability over a range of timescales and wavelengths. Using two optical CoRoT runs, and infrared Spitzer 3.6 and 4.5 $\\mu$m observations (simultaneous with the second CoRoT run), we model the out-of-eclipse light curves. The large scale structure in both CoRoT light curves is consistent with the constructive and destructive interference of starspot signals at two slightly different periods. Using the stellar $v\\sin i$ 's, we infer different rotation periods: the primary is consistent with synchronisation and the secondary is slightly supersynchronous. Comparison of the raw data to the residuals of our spot model in colour-magnitude space indicates additional contributions consistent with variable dust emission and obscuration. We also identify short-duration flux dips preceding secondary eclipse in all three CoRoT and Spitzer ban...

  12. Zodiacal Exoplanets in Time (ZEIT) III: A Neptune-sized planet orbiting a pre-main-sequence star in the Upper Scorpius OB Association

    CERN Document Server

    Mann, Andrew W; Rizzuto, Aaron C; Irwin, Jonathan; Feiden, Gregory A; Gaidos, Eric; Mace, Gregory N; Kraus, Adam L; James, David J; Ansdell, Megan; Charbonneau, David; Covey, Kevin R; Ireland, Michael J; Jaffe, Daniel T; Johnson, Marshall C; Kidder, Benjamin; Vanderburg, Andrew

    2016-01-01

    We confirm and characterize a close-in ($P_\\rm{orb}$ = 5.425 days), super-Neptune sized ($5.04^{+0.34}_{-0.37}$ Earth radii) planet transiting EPIC 205117205 (2MASS J16101473-1919095), a late-type (M3) pre-main sequence ($\\simeq$11 Myr-old) star in the Upper Scorpius subgroup of the Scorpius-Centaurus OB association. The host star has the kinematics of a member of the Upper Scorpius OB association, and its spectrum contains lithium absorption, an unambiguous sign of youth (<20 Myr) in late-type dwarfs. We combine photometry from K2 and the ground-based MEarth project to refine the planet's properties and constrain the average stellar density. We determine EPIC 205117205's bolometric flux and effective temperature from moderate resolution spectra. By utilizing isochrones that include the effects of magnetic fields, we derive a precise (6-7%) radius and mass for the host star, and a stellar age consistent with the established value for Upper Scorpius. Follow-up high-resolution imaging and Doppler spectroscop...

  13. Searching for young Jupiter analogs around AP Col: L-band high-contrast imaging of the closest pre-main sequence star

    CERN Document Server

    Quanz, Sascha P; Janson, Markus; Avenhaus, Henning; Meyer, Michael R; Hillenbrand, Lynne A

    2012-01-01

    The nearby M-dwarf AP Col was recently identified by Riedel et al. 2011 as a pre-main sequence star (age 12 - 50 Myr) situated only 8.4 pc from the Sun. The combination of its youth, distance, and intrinsically low luminosity make it an ideal target to search for extrasolar planets using direct imaging. We report deep adaptive optics observations of AP Col taken with VLT/NACO and Keck/NIRC2 in the L-band. Using aggressive speckle suppression and background subtraction techniques, we are able to rule out companions with mass m >= 0.5 - 1M_Jup for projected separations a>4.5 AU, and m >= 2 M_Jup for projected separations as small as 3 AU, assuming an age of 40 Myr using the COND theoretical evolutionary models. Using a different set of models the mass limits increase by a factor of ~2. The observations presented here are the deepest mass-sensitivity limits yet achieved within 20 AU on a star with direct imaging. While Doppler radial velocity surveys have shown that Jovian bodies with close-in orbits are rare ar...

  14. Pre-Main Sequence variables in the VMR-D : identification of T Tauri-like accreting protostars through Spitzer-IRAC variability

    CERN Document Server

    Giannini, T; Elia, D; Strafella, F; De Luca, M; Fazio, G; Marengo, M; Nisini, B; Smith, H A

    2009-01-01

    We present a study of the infrared variability of young stellar objects by means of two Spitzer-IRAC images of the Vela Molecular Cloud D (VMR-D) obtained in observations separated in time by about six months. By using the same space-born IR instrumentation, this study eliminates all the unwanted effects usually unavoidable when comparing catalogs obtained from different instruments. The VMR-D map covers about 1.5 square deg. of a site where star formation is actively ongoing. We are interested in accreting pre-main sequence variables whose luminosity variations are due to intermittent events of disk accretion (i.e. active T Tauri stars and EXor type objects). The variable objects have been selected from a catalog of more than 170,000 sources detected at a S/N ratio > 5. We searched the sample of variables for ones whose photometric properties are close to those of known EXor's. These latter are monitored in a more systematic way than T Tauri stars and the mechanisms that regulate the observed phenomenology a...

  15. Zodiacal Exoplanets in Time (ZEIT). III. A Short-period Planet Orbiting a Pre-main-sequence Star in the Upper Scorpius OB Association

    Science.gov (United States)

    Mann, Andrew W.; Newton, Elisabeth R.; Rizzuto, Aaron C.; Irwin, Jonathan; Feiden, Gregory A.; Gaidos, Eric; Mace, Gregory N.; Kraus, Adam L.; James, David J.; Ansdell, Megan; Charbonneau, David; Covey, Kevin R.; Ireland, Michael J.; Jaffe, Daniel T.; Johnson, Marshall C.; Kidder, Benjamin; Vanderburg, Andrew

    2016-09-01

    We confirm and characterize a close-in ({P}{{orb}} = 5.425 days), super-Neptune sized ({5.04}-0.37+0.34 {R}\\oplus ) planet transiting K2-33 (2MASS J16101473-1919095), a late-type (M3) pre-main-sequence (11 Myr old) star in the Upper Scorpius subgroup of the Scorpius-Centaurus OB association. The host star has the kinematics of a member of the Upper Scorpius OB association, and its spectrum contains lithium absorption, an unambiguous sign of youth (\\lt 20 Myr) in late-type dwarfs. We combine photometry from K2 and the ground-based MEarth project to refine the planet’s properties and constrain the host star’s density. We determine K2-33’s bolometric flux and effective temperature from moderate-resolution spectra. By utilizing isochrones that include the effects of magnetic fields, we derive a precise radius (6%-7%) and mass (16%) for the host star, and a stellar age consistent with the established value for Upper Scorpius. Follow-up high-resolution imaging and Doppler spectroscopy confirm that the transiting object is not a stellar companion or a background eclipsing binary blended with the target. The shape of the transit, the constancy of the transit depth and periodicity over 1.5 yr, and the independence with wavelength rule out stellar variability or a dust cloud or debris disk partially occulting the star as the source of the signal; we conclude that it must instead be planetary in origin. The existence of K2-33b suggests that close-in planets can form in situ or migrate within ˜10 Myr, e.g., via interactions with a disk, and that long-timescale dynamical migration such as by Lidov-Kozai or planet-planet scattering is not responsible for all short-period planets.

  16. XMM-NEWTON MONITORING OF THE CLOSE PRE-MAIN-SEQUENCE BINARY AK SCO. EVIDENCE OF TIDE-DRIVEN FILLING OF THE INNER GAP IN THE CIRCUMBINARY DISK

    Energy Technology Data Exchange (ETDEWEB)

    Gomez de Castro, Ana Ines [S. D. Astronomia y Geodesia and Instituto de Matematica Interdisciplinar, Fac. de CC Matematicas, Universidad Complutense, E-28040 Madrid (Spain); Lopez-Santiago, Javier [Departamento de Astrofisica, Fac de CC Fisicas, Universidad Complutense, E-28040 Madrid (Spain); Talavera, Antonio [European Space Astronomy Center, Villanueva de la Canada, E-28691, Madrid (Spain); Sytov, A. Yu.; Bisikalo, D. [Institute of Astronomy of the Russian Academy of Sciences, Pyatnitskaya St. 48, 109017 Moscow (Russian Federation)

    2013-03-20

    AK Sco stands out among pre-main-sequence binaries because of its prominent ultraviolet excess, the high eccentricity of its orbit, and the strong tides driven by it. AK Sco consists of two F5-type stars that get as close as 11 R{sub *} at periastron passage. The presence of a dense (n{sub e} {approx} 10{sup 11} cm{sup -3}) extended envelope has been unveiled recently. In this article, we report the results from an XMM-Newton-based monitoring of the system. We show that at periastron, X-ray and UV fluxes are enhanced by a factor of {approx}3 with respect to the apastron values. The X-ray radiation is produced in an optically thin plasma with T {approx} 6.4 Multiplication-Sign 10{sup 6} K and it is found that the N{sub H} column density rises from 0.35 Multiplication-Sign 10{sup 21} cm{sup -2} at periastron to 1.11 Multiplication-Sign 10{sup 21} cm{sup -2} at apastron, in good agreement with previous polarimetric observations. The UV emission detected in the Optical Monitor band seems to be caused by the reprocessing of the high-energy magnetospheric radiation on the circumstellar material. Further evidence of the strong magnetospheric disturbances is provided by the detection of line broadening of 278.7 km s{sup -1} in the N V line with Hubble Space Telescope/Space Telescope Imaging Spectrograph. Numerical simulations of the mass flow from the circumbinary disk to the components have been carried out. They provide a consistent scenario with which to interpret AK Sco observations. We show that the eccentric orbit acts like a gravitational piston. At apastron, matter is dragged efficiently from the inner disk border, filling the inner gap and producing accretion streams that end as ring-like structures around each component of the system. At periastron, the ring-like structures come into contact, leading to angular momentum loss, and thus producing an accretion outburst.

  17. First determination of s-process element abundances in pre-main sequence clusters. Y, Zr, La, and Ce in IC 2391, the Argus association, and IC 2602

    Science.gov (United States)

    D'Orazi, V.; De Silva, G. M.; Melo, C. F. H.

    2017-02-01

    Context. Several high-resolution spectroscopic studies have provided compelling observational evidence that open clusters display a decreasing trend of their barium abundances as a function of the cluster's age. Young clusters (ages ≲ 200 Myr) exhibit significant enhancement in the [Ba/Fe] ratios, at variance with solar-age clusters where the Ba content has been found to be [Ba/Fe] 0 dex. Different viable solutions have been suggested in the literature; nevertheless, a conclusive interpretation of such a peculiar trend has not been found. Interestingly, it is debated whether the other species produced with Ba via s-process reactions follow the same trend with age. Aims: Pre-main sequence clusters (≈10-50 Myr) show the most extreme behaviour in this respect: their [Ba/Fe] ratios can reach 0.65 dex, which is higher than the solar value by a factor of four. Crucially, there are no investigations of the other s-process species for these young stellar populations. In this paper we present the first determination of Y, Zr, La, and Ce in clusters IC 2391, IC 2602, and the Argus association. The main objective of our work is to ascertain whether these elements reveal the same enhancement as Ba. Methods: We have exploited high-resolution, high signal-to-noise spectra in order to derive abundances for Y, Zr, La, and Ce via spectral synthesis calculations. Our sample includes only stars with very similar atmospheric parameters so that internal errors due to star-to-star inhomogeneity are negligible. The chemical analysis was carried out in a strictly differential way, as done in all our previous investigations, to minimise the impact of systematic uncertainties. Results: Our results indicate that, at variance with Ba, all the other s-process species exhibit a solar scaled pattern; these clusters confirm a similar trend discovered in the slightly older local associations (e.g. AB Doradus, Carina-Near), where only Ba exhibit enhanced value with all other s-process species

  18. MEASUREMENT OF SPIN-ORBIT MISALIGNMENT AND NODAL PRECESSION FOR THE PLANET AROUND PRE-MAIN-SEQUENCE STAR PTFO 8-8695 FROM GRAVITY DARKENING

    Energy Technology Data Exchange (ETDEWEB)

    Barnes, Jason W. [Department of Physics, University of Idaho, Moscow, ID 83844-0903 (United States); Van Eyken, Julian C. [Department of Physics, University of California Santa Barbara, Santa Barbara, CA 93106-9530 (United States); Jackson, Brian K. [Carnegie Institution of Washington, DTM, 5241 Broad Branch Road, NW Washington, DC 20015-1305 (United States); Ciardi, David R. [NASA Exoplanet Science Institute, Caltech M/S 100-22, Pasadena, CA 91125 (United States); Fortney, Jonathan J., E-mail: jwbarnes@uidaho.edu [Department of Astronomy, University of California Santa Cruz, Santa Cruz, CA 95064 (United States)

    2013-09-01

    PTFO 8-8695b represents the first transiting exoplanet candidate orbiting a pre-main-sequence star (van Eyken et al. 2012, ApJ, 755, 42). We find that the unusual lightcurve shapes of PTFO 8-8695 can be explained by transits of a planet across an oblate, gravity-darkened stellar disk. We develop a theoretical framework for understanding precession of a planetary orbit's ascending node for the case when the stellar rotational angular momentum and the planetary orbital angular momentum are comparable in magnitude. We then implement those ideas to simultaneously and self-consistently fit two separate lightcurves observed in 2009 December and 2010 December. Our two self-consistent fits yield M{sub p} = 3.0 M{sub Jup} and M{sub p} = 3.6 M{sub Jup} for assumed stellar masses of M{sub *} = 0.34 M{sub Sun} and M{sub *} = 0.44 M{sub Sun} respectively. The two fits have precession periods of 293 days and 581 days. These mass determinations (consistent with previous upper limits) along with the strength of the gravity-darkened precessing model together validate PTFO 8-8695b as just the second hot Jupiter known to orbit an M-dwarf. Our fits show a high degree of spin-orbit misalignment in the PTFO 8-8695 system: 69 Degree-Sign {+-} 2 Degree-Sign or 73. Degree-Sign 1 {+-} 0. Degree-Sign 5, in the two cases. The large misalignment is consistent with the hypothesis that planets become hot Jupiters with random orbital plane alignments early in a system's lifetime. We predict that as a result of the highly misaligned, precessing system, the transits should disappear for months at a time over the course of the system's precession period. The precessing, gravity-darkened model also predicts other observable effects: changing orbit inclination that could be detected by radial velocity observations, changing stellar inclination that would manifest as varying vsin i, changing projected spin-orbit alignment that could be seen by the Rossiter-McLaughlin effect, changing

  19. Can we predict the magnetic properties of PMS stars from their H-R diagram location?

    CERN Document Server

    Gregory, S G; Morin, J; Hussain, G A J; Mayne, N J; Hillenbrand, L A; Jardine, M

    2013-01-01

    Spectropolarimetric observations combined with tomographic imaging techniques have revealed that all pre-main sequence (PMS) stars host multipolar magnetic fields, ranging from strong and globally axisymmetric with ~>kilo-Gauss dipole components, to complex and non-axisymmetric with weak dipole components (<~0.1 kG). Many host dominantly octupolar large-scale fields. We argue that the large-scale magnetic properties of a PMS star are related to its location in the Hertzsprung-Russell diagram. This conference paper is a synopsis of Gregory et al. (2012), updated to include the latest results from magnetic mapping studies of PMS stars.

  20. Optical spectroscopy of X-ray sources in the Taurus molecular cloud: discovery of ten new pre-main sequence stars

    CERN Document Server

    Scelsi, L; Affer, L; Argiroffi, C; Pillitteri, I; Maggio, A; Micela, G

    2008-01-01

    We have analyzed optical spectra of 25 X-ray sources identified as potential new members of the Taurus molecular cloud (TMC), in order to confirm their membership in this SFR. Fifty-seven candidates were previously selected among the X-ray sources in the XEST survey, having a 2MASS counterpart compatible with a PMS star based on color-magnitude and color-color diagrams. We obtained high-resolution optical spectra for 7 of these candidates with the SARG spectrograph at the TNG telescope, which were used to search for Li absorption and to measure the Ha line and the radial and rotational velocities; 18 low-resolution optical spectra obtained with DOLORES for other candidate members were used for spectral classification, for Ha measurements, and to assess membership together with IR color-color and color-magnitude diagrams and additional information from the X-ray data. We found that 3 sources show Li absorption, with equivalent widths of ~500 mA, broad spectral line profiles, indicating v sin i ~20-40 km/s, rad...

  1. A Tale of Two Anomalies: Depletion, Dispersion, and the Connection Between the Stellar Lithium Spread and Inflated Radii on the Pre-Main Sequence

    CERN Document Server

    Somers, Garrett

    2014-01-01

    We investigate lithium depletion in standard stellar models (SSMs) and main sequence (MS) open clusters, and explore the origin of the Li dispersion in young, cool stars of equal mass, age and composition. We first demonstrate that SSMs accurately predict the Li abundances of solar analogs at the zero-age main sequence (ZAMS) within theoretical uncertainties. We then measure the rate of MS Li depletion by removing the [Fe/H]-dependent ZAMS Li pattern from three well-studied clusters, and comparing the detrended data. MS depletion is found to be mass dependent, in the sense of more depletion at low mass. A dispersion in Li abundance at fixed $T_{\\rm eff}$ is nearly universal, and sets in by $\\sim$200 Myr. We discuss mass and age dispersion trends, and the pattern is mixed. We argue that metallicity impacts the ZAMS Li pattern, in agreement with theoretical expectations but contrary to the findings of some previous studies, and suggest Li as a test of cluster metallicity. Finally, we argue that a radius dispers...

  2. A Tale of Two Anomalies: Depletion, Dispersion, and the Connection between the Stellar Lithium Spread and Inflated Radii on the Pre-main Sequence

    Science.gov (United States)

    Somers, Garrett; Pinsonneault, Marc H.

    2014-07-01

    We investigate lithium depletion in standard stellar models (SSMs) and main sequence (MS) open clusters, and explore the origin of the Li dispersion in young, cool stars of equal mass, age, and composition. We first demonstrate that SSMs accurately predict the Li abundances of solar analogs at the zero-age main sequence (ZAMS) within theoretical uncertainties. We then measure the rate of MS Li depletion by removing the [Fe/H]-dependent ZAMS Li pattern from three well-studied clusters, and comparing the detrended data. MS depletion is found to be mass-dependent, in the sense of more depletion at low mass. A dispersion in Li abundance at fixed T eff is nearly universal, and sets in by ~200 Myr. We discuss mass and age dispersion trends, and the pattern is mixed. We argue that metallicity impacts the ZAMS Li pattern, in agreement with theoretical expectations but contrary to the findings of some previous studies, and suggest Li as a test of cluster metallicity. Finally, we argue that a radius dispersion in stars of fixed mass and age, during the epoch of pre-MS Li destruction, is responsible for the spread in Li abundances and the correlation between rotation and Li in young cool stars, most well known in the Pleiades. We calculate stellar models, inflated to match observed radius anomalies in magnetically active systems, and the resulting range of Li abundances reproduces the observed patterns of young clusters. We discuss ramifications for pre-MS evolutionary tracks and age measurements of young clusters, and suggest an observational test.

  3. A tale of two anomalies: Depletion, dispersion, and the connection between the stellar lithium spread and inflated radii on the pre-main sequence

    Energy Technology Data Exchange (ETDEWEB)

    Somers, Garrett; Pinsonneault, Marc H., E-mail: somers@astronomy.ohio-state.edu, E-mail: pinsono@astronomy.ohio-state.edu [Department of Astronomy, The Ohio State University, 140 West 18th Avenue, Columbus, OH 43201 (United States)

    2014-07-20

    We investigate lithium depletion in standard stellar models (SSMs) and main sequence (MS) open clusters, and explore the origin of the Li dispersion in young, cool stars of equal mass, age, and composition. We first demonstrate that SSMs accurately predict the Li abundances of solar analogs at the zero-age main sequence (ZAMS) within theoretical uncertainties. We then measure the rate of MS Li depletion by removing the [Fe/H]-dependent ZAMS Li pattern from three well-studied clusters, and comparing the detrended data. MS depletion is found to be mass-dependent, in the sense of more depletion at low mass. A dispersion in Li abundance at fixed T{sub eff} is nearly universal, and sets in by ∼200 Myr. We discuss mass and age dispersion trends, and the pattern is mixed. We argue that metallicity impacts the ZAMS Li pattern, in agreement with theoretical expectations but contrary to the findings of some previous studies, and suggest Li as a test of cluster metallicity. Finally, we argue that a radius dispersion in stars of fixed mass and age, during the epoch of pre-MS Li destruction, is responsible for the spread in Li abundances and the correlation between rotation and Li in young cool stars, most well known in the Pleiades. We calculate stellar models, inflated to match observed radius anomalies in magnetically active systems, and the resulting range of Li abundances reproduces the observed patterns of young clusters. We discuss ramifications for pre-MS evolutionary tracks and age measurements of young clusters, and suggest an observational test.

  4. Angular momentum transport by internal gravity waves. IV - Wave generation by surface convection zone, from the pre-main sequence to the early-AGB in intermediate mass stars

    CERN Document Server

    Talon, Suzanne

    2008-01-01

    This is the fourth in a series of papers that deal with angular momentum transport by internal gravity waves in stellar interiors. Here, we want to examine the potential role of waves in other evolutionary phases than the main sequence. We study the evolution of a 3Msun Population I model from the pre-main sequence to the early-AGB phase and examine whether waves can lead to angular momentum redistribution and/or element diffusion at the external convection zone boundary. We find that, although waves produced by the surface convection zone can be ignored safely for such a star during the main sequence, it is not the case for later evolutionary stages. In particular, angular momentum transport by internal waves could be quite important at the end of the sub-giant branch and during the early-AGB phase. Wave-induced mixing of chemicals is expected during the early-AGB phase.

  5. Impact of initial models and variable accretion rates on the pre-main-sequence evolution of massive and intermediate-mass stars and the early evolution of HII regions

    CERN Document Server

    Haemmerlé, Lionel

    2016-01-01

    Massive star formation requires the accretion of gas at high rate while the star is already bright. Its actual luminosity depends sensitively on the stellar structure. We compute pre-main-sequence tracks for massive and intermediate-mass stars with variable accretion rates and study the evolution of stellar radius, effective temperature and ionizing luminosity, starting at $2\\,M_\\odot$ with convective or radiative structures. The radiative case shows a much stronger swelling of the protostar for high accretion rates than the convective case. For radiative structures, the star is very sensitive to the accretion rate and reacts quickly to accretion bursts, leading to considerable changes in photospheric properties on timescales as short as 100 - 1000 yr. The evolution for convective structures is much less influenced by the instantaneous accretion rate, and produces a monotonically increasing ionizing flux that can be many orders of magnitude smaller than in the radiative case. For massive stars, it results in ...

  6. Impact of initial models and variable accretion rates on the pre-main-sequence evolution of massive and intermediate-mass stars and the early evolution of H II regions

    Science.gov (United States)

    Haemmerlé, Lionel; Peters, Thomas

    2016-05-01

    Massive star formation requires the accretion of gas at high rate while the star is already bright. Its actual luminosity depends sensitively on the stellar structure. We compute pre-main-sequence tracks for massive and intermediate-mass stars with variable accretion rates and study the evolution of stellar radius, effective temperature and ionizing luminosity, starting at 2 M⊙ with convective or radiative structures. The radiative case shows a much stronger swelling of the protostar for high accretion rates than the convective case. For radiative structures, the star is very sensitive to the accretion rate and reacts quickly to accretion bursts, leading to considerable changes in photospheric properties on time-scales as short as 100-1000 yr. The evolution for convective structures is much less influenced by the instantaneous accretion rate, and produces a monotonically increasing ionizing flux that can be many orders of magnitude smaller than in the radiative case. For massive stars, it results in a delay of the H II region expansion by up to 10 000 yr. In the radiative case, the H II region can potentially be engulfed by the star during the swelling, which never happens in the convective case. We conclude that the early stellar structure has a large impact on the radiative feedback during the pre-main-sequence evolution of massive protostars and introduces an important uncertainty that should be taken into account. Because of their lower effective temperatures, our convective models may hint at a solution to an observed discrepancy between the luminosity distribution functions of massive young stellar objects and compact H II regions.

  7. High-precision Radio and Infrared Astrometry of LSPM J1314+1320AB. II. Testing Pre-main-sequence Models at the Lithium Depletion Boundary with Dynamical Masses

    Science.gov (United States)

    Dupuy, Trent J.; Forbrich, Jan; Rizzuto, Aaron; Mann, Andrew W.; Aller, Kimberly; Liu, Michael C.; Kraus, Adam L.; Berger, Edo

    2016-08-01

    We present novel tests of pre-main-sequence models based on individual dynamical masses for the M7 binary LSPM J1314+1320AB. Joint analysis of Keck adaptive optics astrometric monitoring along with Very Long Baseline Array radio data from a companion paper yield component masses of 92.8 ± 0.6 M Jup (0.0885 ± 0.0006 M ⊙) and 91.7 ± 1.0 M Jup (0.0875 ± 0.0010 M ⊙) and a parallactic distance of 17.249 ± 0.013 pc. We find component luminosities consistent with the system being coeval at 80.8 ± 2.5 Myr, according to BHAC15 evolutionary models. The presence of lithium is consistent with model predictions, marking the first test of the theoretical lithium depletion boundary using ultracool dwarfs of known mass. However, we find that the evolutionary model-derived average effective temperature (2950 ± 5 K) is 180 K hotter than that given by a spectral type-{T}{eff} relation based on BT-Settl models (2770 ± 100 K). We suggest that the dominant source of this discrepancy is model radii being too small by ≈13%. In a test mimicking the typical application of models by observers, we derive masses on the H-R diagram using luminosity and BT-Settl temperature. The estimated masses are lower by {46}-19+16 % (2.0σ) than we measure dynamically and would imply that this is a system of ≈50 M Jup brown dwarfs, highlighting the large systematic errors possible in H-R diagram properties. This is the first time masses have been measured for ultracool (≥M6) dwarfs displaying spectral signatures of low gravity. Based on features in the infrared, LSPM J1314+1320AB appears to have higher gravity than typical Pleiades and AB Dor members, opposite the expectation given its younger age. The components of LSPM J1314+1320AB are now the nearest, lowest mass pre-main-sequence stars with direct mass measurements. Data presented herein were obtained at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the

  8. Magnetic fields and differential rotation on the pre-main sequence II: The early-G star HD 141943 - coronal magnetic field, H-alpha emission and differential rotation

    CERN Document Server

    Marsden, S C; Vélez, J C Ramírez; Alecian, E; Brown, C J; Carter, B D; Donati, J F; Dunstone, N; Hart, R; Semel, M; Waite, I A

    2011-01-01

    Spectropolarimetric observations of the pre-main sequence early-G star HD 141943 were obtained at three observing epochs (2007, 2009 and 2010). The observations were obtained using the 3.9-m Anglo-Australian telescope with the UCLES echelle spectrograph and the SEMPOL spectropolarimeter visitor instrument. The brightness and surface magnetic field topologies (given in Paper I) were used to determine the star's surface differential rotation and reconstruct the coronal magnetic field of the star. The coronal magnetic field at the 3 epochs shows on the largest scales that the field structure is dominated by the dipole component with possible evidence for the tilt of the dipole axis shifting between observations. We find very high levels of differential rotation on HD 141943 (~8 times the solar value for the magnetic features and ~5 times solar for the brightness features) similar to that evidenced by another young early-G star, HD 171488. These results indicate that a significant increase in the level of differe...

  9. High-Precision Radio and Infrared Astrometry of LSPM J1314+1320AB - II: Testing Pre--Main-Sequence Models at the Lithium Depletion Boundary with Dynamical Masses

    CERN Document Server

    Dupuy, Trent J; Rizzuto, Aaron; Mann, Andrew W; Aller, Kimberly; Liu, Michael C; Kraus, Adam L; Berger, Edo

    2016-01-01

    We present novel tests of pre$-$main-sequence models based on individual dynamical masses for the M7 binary LSPM J1314+1320AB. Joint analysis of our Keck adaptive optics astrometric monitoring along with Very Long Baseline Array radio data from a companion paper yield component masses of $0.0885\\pm0.0006$ $M_{\\odot}$ and $0.0875\\pm0.0010$ $M_{\\odot}$ and a parallactic distance of $17.249\\pm0.013$ pc. We also derive component luminosities that are consistent with the system being coeval at an age of $80.8\\pm2.5$ Myr, according to BHAC15 evolutionary models. The presence of lithium is consistent with model predictions, marking the first time the theoretical lithium depletion boundary has been tested with ultracool dwarfs of known mass. However, we find that the average evolutionary model-derived effective temperature ($2950\\pm5$ K) is 180 K hotter than we derive from a spectral type$-$$T_{\\rm eff}$ relation based on BT-Settl models ($2770\\pm100$ K). We suggest that the dominant source of this discrepancy is mod...

  10. HD 98800: An Opportunity to Measure True Masses for Low-Mass PMS Stars

    Science.gov (United States)

    Soderblom, David

    1999-07-01

    HD 98800 became interesting when IRAS found it to have a large infrared excess, indicating a substantial dust disk. But ``HD 98800'' is, in fact, a quadruple system consisting of four K and M stars, and its Hipparcos parallax has now shown that this is a pre-main sequence system. The four stars are in two visible objects, each of which is a spectroscopic binary with a period of about one year. In particular, the Ba-Bb pair is an SB2 with an estimated semi-major axis of about 20 milliarcsec. In TRANS mode, FGS1R can cleanly resolve the Ba-Bb pair and can determine the relative orbit and luminosities for the two components. POS mode observations lead to an absolute orbit and a more precise parallax than is currently available. In this program we propose to follow the HD 98800 Ba-Bb pair over the course of a full orbit during Cycle 8. The combination of FGS1R-TRANS and FGS1R-POS observations will provide gravitational masses for two low-mass PMS stars. In addition, the co nstraints of coevality and knowled ge of the astrophysical properties of the components {temperatures, luminosities, composition} make these observations a crucial test of our models of pre-main sequence evolution. These may be the first true masses determined for low-mass PMS objects, and so can provide a fundamental test of PMS evolutionary tracks.

  11. Premenstrual Syndrome (PMS) FAQ

    Science.gov (United States)

    ... syndrome irritable bowel syndrome thyroid disease Depression and anxiety disorders are the most common conditions that overlap with PMS. About one half of women seeking treatment for PMS have one of these ...

  12. Premenstrual Syndrome (PMS) FAQ

    Science.gov (United States)

    ... PMS symptoms. Relaxation therapy may include breathing exercises, meditation, and yoga. Massage therapy is another form of relaxation therapy that you may want to try. Some women find therapies like biofeedback and self-hypnosis to be helpful. Getting enough ...

  13. Thermohaline instability and rotation-induced mixing. III - Grid of stellar models and asymptotic asteroseismic quantities from the pre-main sequence up to the AGB for low- and intermediate-mass stars at various metallicities

    CERN Document Server

    Lagarde, N; Charbonnel, C; Eggenberger, P; Ekström, S; Palacios, A

    2012-01-01

    The availability of asteroseismic constraints for a large sample of stars from the missions CoRoT and Kepler paves the way for various statistical studies of the seismic properties of stellar populations. In this paper, we evaluate the impact of rotation-induced mixing and thermohaline instability on the global asteroseismic parameters at different stages of the stellar evolution from the Zero Age Main Sequence to the Thermally Pulsating Asymptotic Giant Branch to distinguish stellar populations. We present a grid of stellar evolutionary models for four metallicities (Z = 0.0001, 0.002, 0.004, and 0.014) in the mass range between 0.85 to 6.0 Msun. The models are computed either with standard prescriptions or including both thermohaline convection and rotation-induced mixing. For the whole grid we provide the usual stellar parameters (luminosity, effective temperature, lifetimes, ...), together with the global seismic parameters, i.e. the large frequency separation and asymptotic relations, the frequency corre...

  14. Pre-main sequence spectroscopic binaries suitable for VLTI observations

    CERN Document Server

    Guenther, E W; Mundt, R; Covino, E; Alcalá, J M; Cusano, F; Stecklum, B

    2007-01-01

    A severe problem of the research in star-formation is that the masses of young stars are almost always estimated only from evolutionary tracks. Since the tracks published by different groups differ, it is often only possible to give a rough estimate of the masses of young stars. It is thus crucial to test and calibrate the tracks. Up to now, only a few tests of the tracks could be carried out. However, with the VLTI it is now possible to set constrains on the tracks by determining the masses of many young binary stars precisely. In order to use the VLTI efficiently, a first step is to find suitable targets, which is the purpose of this work. Given the distance of nearby star-forming regions, suitable VLTI targets are binaries with orbital periods between at least 50 days, and few years. Although a number of surveys for detecting spectroscopic binaries have been carried out, most of the binaries found so far have periods which are too short. We thus surveyed the Chamaeleon, Corona Australis, Lupus, Sco-Cen, rh...

  15. Orbital Parameters for a Pre-Main Sequence Binary System

    Science.gov (United States)

    Karnath, Nicole; Prato, L.; Wasserman, L.

    2011-01-01

    The young system VSB 111 was originally classified as a single-lined spectroscopic binary in the star forming region of NGC 2264. Using the Keck II telescope we measured radial velocities for both the primary and secondary components in the infrared. By combining these data with previous visible light observations of the primary star, we derived the period, eccentricity, and other orbital parameters, as well as the mass ratio of the system. With additional information gained from further observations, for example the inclination derived from the angularly resolved orbit, we will eventually obtain the individual stellar masses, necessary to help to calibrate models of young star evolution. Furthermore, by compiling dozens or even hundreds of mass ratios for young binaries we can use mass ratio distributions to improve our understanding of binary star formation. No infrared excess or any other indication of a circumstellar disk is in evidence for VSB 111, indicating that either the accretion rate has dropped to an undetectable value or that this system has aged enough that its disk has dissipated, if originally present. Given the approximately 900 day period of this system, and its relatively high eccentricity, 0.8, the action of the companion could have been responsible for early dissipation of any disk material.

  16. Chemical analysis of 24 dusty (pre-)main-sequence stars

    CERN Document Server

    Acke, B; Acke, Bram; Waelkens, Christoffel

    2004-01-01

    We have analysed the chemical photospheric composition of 24 Herbig Ae/Be and Vega-type stars in search for the lambda Bootis phenomenon. We present the results of the elemental abundances of the sample stars. Some of the stars were never before studied spectroscopically at optical wavelengths. We have determined the projected rotational velocities of our sample stars. Furthermore, we discuss stars that depict a (selective) depletion pattern in detail. HD 4881 and HD 139614 seem to display an overall deficiency. AB Aur and possibly HD 126367 have subsolar values for the iron abundance, but are almost solar in silicon. HD 100546 is the only clear lambda Bootis star in our sample.

  17. The PMS project Poor Man's Supercomputer

    CERN Document Server

    Csikor, Ferenc; Hegedüs, P; Horváth, V K; Katz, S D; Piróth, A

    2001-01-01

    We briefly describe the Poor Man's Supercomputer (PMS) project that is carried out at Eotvos University, Budapest. The goal is to develop a cost effective, scalable, fast parallel computer to perform numerical calculations of physical problems that can be implemented on a lattice with nearest neighbour interactions. To reach this goal we developed the PMS architecture using PC components and designed a special, low cost communication hardware and the driver software for Linux OS. Our first implementation of the PMS includes 32 nodes (PMS1). The performance of the PMS1 was tested by Lattice Gauge Theory simulations. Using SU(3) pure gauge theory or bosonic MSSM on the PMS1 computer we obtained 3$/Mflops price-per-sustained performance ratio. The design of the special hardware and the communication driver are freely available upon request for non-profit organizations.

  18. qPMS9: An Efficient Algorithm for Quorum Planted Motif Search

    Science.gov (United States)

    Nicolae, Marius; Rajasekaran, Sanguthevar

    2015-01-01

    Discovering patterns in biological sequences is a crucial problem. For example, the identification of patterns in DNA sequences has resulted in the determination of open reading frames, identification of gene promoter elements, intron/exon splicing sites, and SH RNAs, location of RNA degradation signals, identification of alternative splicing sites, etc. In protein sequences, patterns have led to domain identification, location of protease cleavage sites, identification of signal peptides, protein interactions, determination of protein degradation elements, identification of protein trafficking elements, discovery of short functional motifs, etc. In this paper we focus on the identification of an important class of patterns, namely, motifs. We study the (l, d) motif search problem or Planted Motif Search (PMS). PMS receives as input n strings and two integers l and d. It returns all sequences M of length l that occur in each input string, where each occurrence differs from M in at most d positions. Another formulation is quorum PMS (qPMS), where the motif appears in at least q% of the strings. We introduce qPMS9, a parallel exact qPMS algorithm that offers significant runtime improvements on DNA and protein datasets. qPMS9 solves the challenging DNA (l, d)-instances (28, 12) and (30, 13). The source code is available at https://code.google.com/p/qpms9/.

  19. Accretion in the Rho-Oph pre-main sequence stars

    CERN Document Server

    Natta, A; Testi, L

    2006-01-01

    The aim of this paper is to provide a measurement of the mass accretion rate in a large, complete sample of objects in the core of the star forming region Rho-Oph. The sample includes most of the objects (104 out of 111) with evidence of a circumstellar disk from mid-infrared photometry; it covers a stellar mass range from about 0.03 to 3 Msun and it is complete to a limiting mass of ~0.05 Msun. We used J and K-band spectra to derive the mass accretion rate of each object from the intensity of the hydrogen recombination lines, Pab or Brg. For comparison, we also obtained similar spectra of 35 diskless objects. The results show that emission in these lines is only seen in stars with disks, and can be used as an indicator of accretion. However, the converse does not hold, as about 50% of our disk objects do not have detectable line emission. The measured accretion rates show a strong correlation with the mass of the central object (Macc ~ Mstar^1.8+-0.2) and a large spread, of two orders of magnitude at least, ...

  20. YSOVAR: Six Pre-main-sequence Eclipsing Binaries in the Orion Nebula Cluster

    Science.gov (United States)

    2012-06-25

    includes background subtraction, cosmic -hit removal, flat-fielding, and wavelength calibration. 23 http://www2.keck.hawaii.edu/inst/nirspec-old/redspec...Inclination and combined radius are highly degenerated; inclination and temperature ratio are less so, but also provide weaker constraints. (A color version of...example, the model isochrones of Siess et al. (2000) predict a radius sum of 11.1–14.5R for ages in the range of 0.3–2 Myr. 5.2. ISOY J0535−0447 ISOY

  1. Active Phenomena in the Pre-main Sequence Star AB AUR

    Science.gov (United States)

    Praderie, F.; Simon, T.; Boesgaard, A. M.; Felenbok, P.; Catala, C.; Czarny, J.; Talavera, A.

    1985-01-01

    The Herbig Ae star AB Aur presents short time scale variability in the Mg II and Ca II resonance lines. A qualitative model of the expanding envelope, involving fast and slow streams in a co-rotating structure, is proposed to explain the Mg II spectral variability.

  2. Old pre-main-sequence Stars: Disc reformation by Bondi-Hoyle accretion

    CERN Document Server

    Scicluna, P; Dale, J E; Testi, L

    2014-01-01

    Young stars show evidence of accretion discs which evolve quickly and disperse with an e-folding time of $\\sim$ 3Myr. This is in striking contrast with recent observations that suggest evidence for numerous $>30$ Myr old stars with an accretion disc in large star-forming complexes. We consider whether these observations of apparently old accretors could be explained by invoking Bondi-Hoyle accretion to rebuild a new disc around these stars during passage through a clumpy molecular cloud. We combine a simple Monte Carlo model to explore the capture of mass by such systems with a viscous evolution model to infer the levels of accretion that would be observed. We find that a significant fraction of stars may capture enough material via the Bondi-Hoyle mechanism to rebuild a disc of mass $\\gtrsim$ 1 minimum-mass solar nebula, and $\\lesssim 10\\%$ accrete at observable levels at any given time. A significant fraction of the observed old accretors may be explained with our proposed mechanism. Such accretion may prov...

  3. Pre-main sequence stars with disks in the Eagle Nebula observed in scattered light

    CERN Document Server

    Guarcello, M G; Micela, G; Peres, G; Prisinzano, L; Sciortino, S

    2010-01-01

    NGC6611 and its parental cloud, the Eagle Nebula (M16), are well-studied star-forming regions, thanks to their large content of both OB stars and stars with disks and the observed ongoing star formation. We identified 834 disk-bearing stars associated with the cloud, after detecting their excesses in NIR bands from J band to 8.0 micron. In this paper, we study in detail the nature of a subsample of disk-bearing stars that show peculiar characteristics. They appear older than the other members in the V vs. V-I diagram, and/or they have one or more IRAC colors at pure photospheric values, despite showing NIR excesses, when optical and infrared colors are compared. We confirm the membership of these stars to M16 by a spectroscopic analysis. The physical properties of these stars with disks are studied by comparing their spectral energy distributions (SEDs) with the SEDs predicted by models of T-Tauri stars with disks and envelopes. We show that the age of these stars estimated from the V vs. V-I diagram is unrel...

  4. An unusual very low-mass high-amplitude pre-main sequence periodic variable

    CERN Document Server

    Rodriguez-Ledesma, Maria V; Ibrahimov, Mansur; Messina, Sergio; Parihar, Padmakar; Hessman, Frederic; de Oliveira, Catarina Alves; Herbst, William

    2012-01-01

    We have investigated the nature of the variability of CHS7797, an unusual periodic variable in the Orion Nebula Cluster. An extensive I-band photometric data set of CHS7797 was compiled between 2004-2010 using various telescopes. Further optical data have been collected in R and z' bands. In addition, simultaneous observations of the ONC region including CHS7797 were performed in the I, J, Ks and IRAC [3.6] and [4.5] bands over a time interval of about 40d. CHS7797 shows an unusual large-amplitude variation of about 1.7 mag in the R, I, and z' bands with a period 17.786. The amplitude of the brightness modulation decreases only slightly at longer wavelengths. The star is faint during 2/3 of the period and the shape of the phased light-curves for seven different observing seasons shows minor changes and small-amplitude variations. Interestingly, there are no significant colour-flux correlations for wavelengths smaller than 2microns, while the object becomes redder when fainter at longer wavelengths. CHS7797 ha...

  5. The pre-main sequence population of NGC 6530 in M8

    Directory of Open Access Journals (Sweden)

    J. I. Arias

    2006-01-01

    Full Text Available Presentamos los resultados de una investigaci on de probables miembros d ebiles del c umulo abierto muy joven NGC 6530 en M8, basados en espectroscop a de resoluci on intermedia obtenida con el telescopio Magallanes I de 6.5 m del Observatorio Las Campanas. El an alisis de los espectros condujo al descubrimiento de 39 nuevas estrellas de pre-secuencia principal en la regi on. De acuerdo a los tipos espectrales, y a la presencia de l neas de emisi on y de l nea de absorci on de litio, identi camos 30 estrellas T-Tauri cl asicas, 7 estrellas T-Tauri d ebiles y dos objetos Herbig Ae/Be. Utilizando magnitudes infrarrojas de 2MASS y de nuestro trabajo previo, y las huellas evolutivas de Palla & Stahler (1999, estimamos las masas y edades de estas estrellas. Encontramos que casi todas las estrellas de nuestra muestra son m as j ovenes que 3 106 a~nos y abarcan un intervalo de masas de entre 0.8 y 2.0 M .

  6. Pre-main-sequence population in NGC 1893 region: X-ray properties

    CERN Document Server

    Pandey, A K; Yadav, Ram Kesh; Richichi, Andrea; Lata, Sneh; Pandey, J C; Ojha, D K; Chen, W P

    2013-01-01

    Continuing the attempt to understand the properties of the stellar content in the young cluster NGC 1893 we have carried out a comprehensive multi-wavelength study of the region. The present study focuses on the X-ray properties of T-Tauri Stars (TTSs) in the NGC 1893 region. We found a correlation between the X-ray luminosity, $L_X$, and the stellar mass (in the range 0.2$-$2.0 \\msun) of TTSs in the NGC 1893 region, similar to those reported in some other young clusters, however the value of the power-law slope obtained in the present study ($\\sim$ 0.9) for NGC 1893 is smaller than those ($\\sim$1.4 - 3.6) reported in the case of TMC, ONC, IC 348 and Chameleon star forming regions. However, the slope in the case of Class III sources (Weak line TTSs) is found to be comparable to that reported in the case of NGC 6611 ($\\sim$ 1.1). It is found that the presence of circumstellar disks has no influence on the X-ray emission. The X-ray luminosity for both CTTSs and WTTSs is found to decrease systematically with age...

  7. The Structure of the Accretion Flow on pre-main-sequence stars

    Science.gov (United States)

    Calvet, Nuria

    1999-07-01

    We propose to test an essential prediction of the magnetospheric accretion model for T Tauri stars. STIS echelle spectra will be used to search for the relatively narrow high-temperature emission lines that must result from the magnetospheric accretion shock, but are not expected in the previous, alternative boundary layer model. By combining the results from high temperature {10^5 K} lines, accessible only with HST, with optical lines and optical-UV continuum emission, we will develop physically self-consistent models of accretion shock structure. The geometrically distribution of the emitting gas as derived from our results will test theories of mass-loading of magnetic field lines at the magnetosphere-disk interface. Analysis of the UV emission lines will also provide improved calibrations between ultraviolet continuum emission and accretion luminosities, and thus improve estimates of mass accretion rates for T Tauri stars.

  8. Extreme value statistics for two-dimensional convective penetration in a pre-main sequence star

    Science.gov (United States)

    Pratt, J.; Baraffe, I.; Goffrey, T.; Constantino, T.; Viallet, M.; Popov, M. V.; Walder, R.; Folini, D.

    2017-08-01

    Context. In the interior of stars, a convectively unstable zone typically borders a zone that is stable to convection. Convective motions can penetrate the boundary between these zones, creating a layer characterized by intermittent convective mixing, and gradual erosion of the density and temperature stratification. Aims: We examine a penetration layer formed between a central radiative zone and a large convection zone in the deep interior of a young low-mass star. Using the Multidimensional Stellar Implicit Code (MUSIC) to simulate two-dimensional compressible stellar convection in a spherical geometry over long times, we produce statistics that characterize the extent and impact of convective penetration in this layer. Methods: We apply extreme value theory to the maximal extent of convective penetration at any time. We compare statistical results from simulations which treat non-local convection, throughout a large portion of the stellar radius, with simulations designed to treat local convection in a small region surrounding the penetration layer. For each of these situations, we compare simulations of different resolution, which have different velocity magnitudes. We also compare statistical results between simulations that radiate energy at a constant rate to those that allow energy to radiate from the stellar surface according to the local surface temperature. Results: Based on the frequency and depth of penetrating convective structures, we observe two distinct layers that form between the convection zone and the stable radiative zone. We show that the probability density function of the maximal depth of convective penetration at any time corresponds closely in space with the radial position where internal waves are excited. We find that the maximal penetration depth can be modeled by a Weibull distribution with a small shape parameter. Using these results, and building on established scalings for diffusion enhanced by large-scale convective motions, we propose a new form for the diffusion coefficient that may be used for one-dimensional stellar evolution calculations in the large Péclet number regime. These results should contribute to the 321D link.

  9. Dust photophoretic transport in a disk irradiated by an evolving PMS star

    Science.gov (United States)

    Cordier, D.; Moroni, P.; Tognelli, E.

    2014-04-01

    As reported by Tielens et al. (2005) [14] the interstellar medium (ISM) is very poor in crystalline solids. For instance, Kemper et al. (2004) [7] well reproduce the interstellar absorption band using a mixture of 15.1% amorphous pyroxene and 84.9% of amorphous olivine by mass, leading to a crystalline fraction of the interstellar silicates around 0.2% by mass. The proto-solar nebula is supposed to be formed from the material coming from the ISM. As a consequence, the primordial dust in the solar system should be composed of amorphous solids excepted grains which have undergone thermal annealing in high temperature regions (i.e. around 1000-1500 K) close to the star (i.e. r . 1 - 2 AU). Besides this, comets are presumed to have formed in the cold outer part of the solar nebula. Campins & Ryan (1989) have found that crystalline olivine is a major component of the silicates in comet Halley. Stardust samples of comet 81P/Wild 2 include large singleminerals crystals and X-raymicroscopic analysis leads to a crystal mass fraction fcryst larger than ~ 50% (Ogliore et al. 2009, Brownlee et al. 2006). More generally comets have a fcryst larger than ~ 20% (Lindsay et al. 2013, Kelley & Wooden, 2009). This discrepancy between ISMgrains crystallinity and comets one is the mark of a radial transport process occuring in the accretion disk. Several transport processes have been proposed to explain the presence of these refractory material in comets: annealing by shock waves in the outer solar nebula (Harker & Desch 2002) [3], radial mixing processes by turbulent diffusion (Gail, 2001; Wehrstedt & Gail, 2002; Bockelée-Morvan et al., 2002) or transport by photophoresis (Mousis et al., 2007 andMoudens et al., 2011). In this paper, we focus on this last process for which we employ a 1+1D accretion disk model irradiated by a pre-main sequence (PMS) star. The model of nebula and the model of star are both evolving. Concerning the photophoresis itself, essentially, we have followed the

  10. Premenstrual Dysphoric Disorder (PMDD): Different from PMS?

    Science.gov (United States)

    ... The cause of PMDD isn't clear. Underlying depression and anxiety are common in both PMS and PMDD, so ... before trying one. Diet and lifestyle changes. Regular exercise often ... smoking may ease symptoms, too. Getting enough sleep and using relaxation ...

  11. Top Performing PMs: How DAU Develops Them

    Science.gov (United States)

    2015-12-01

    demand highly talented PMs who can deliver needed products and services to our military customers . The DAU’s challenge is to make its training and...shorter courses taken along a PM’s career path. The current PM training framework is shown in Figure 1. To reach Level III certification requires 346...management skills, so it is often their leadership skills that most need development. This is illustrated in the career development timeline in

  12. Detection of large scale 3' deletions in the PMS2 gene amongst Colon-CFR participants: have we been missing anything?

    Science.gov (United States)

    Clendenning, Mark; Walsh, Michael D; Gelpi, Judith Balmana; Thibodeau, Stephen N; Lindor, Noralane; Potter, John D; Newcomb, Polly; LeMarchand, Loic; Haile, Robert; Gallinger, Steve; Hopper, John L; Jenkins, Mark A; Rosty, Christophe; Young, Joanne P; Buchanan, Daniel D

    2013-09-01

    Current screening practices have been able to identify PMS2 mutations in 78 % of cases of colorectal cancer from the Colorectal Cancer Family Registry (Colon CFR) which showed solitary loss of the PMS2 protein. However the detection of large-scale deletions in the 3' end of the PMS2 gene has not been possible due to technical difficulties associated with pseudogene sequences. Here, we utilised a recently described MLPA/long-range PCR-based approach to screen the remaining 22 % (n = 16) of CRC-affected probands for mutations in the 3' end of the PMS2 gene. No deletions encompassing any or all of exons 12 through 15 were identified; therefore, our results suggest that 3' deletions in PMS2 are not a frequent occurrence in such families.

  13. Planar CMOS analog SiPMs: design, modeling, and characterization

    Science.gov (United States)

    Zou, Yu; Villa, Federica; Bronzi, Danilo; Tisa, Simone; Tosi, Alberto; Zappa, Franco

    2015-11-01

    Silicon photomultipliers (SiPMs) are large area detectors consisting of an array of single-photon-sensitive microcells, which make SiPMs extremely attractive to substitute the photomultiplier tubes in many applications. We present the design, fabrication, and characterization of analog SiPMs in standard planar 0.35 μm CMOS technology, with about 1 mm × 1 mm total area and different kinds of microcells, based on single-photon avalanche diodes with 30 μm diameter reaching 21.0% fill-factor (FF), 50 μm diameter (FF = 58.3%) or 50 μm square active area with rounded corner of 5 μm radius (FF = 73.7%). We also developed the electrical SPICE model for CMOS SiPMs. Our CMOS SiPMs have 25 V breakdown voltage, in line with most commercial SiPMs and higher gain (8.8 × 106, 13.2 × 106, and 15.0 × 106, respectively). Although dark count rate density is slightly higher than state-of-the-art analog SiPMs, the proposed standard CMOS processing opens the feasibility of integration with active electronics, for switching hot pixels off, drastically reducing the overall dark count rate, or for further on-chip processing.

  14. Dominant mutations in S. cerevisiae PMS1 identify the Mlh1-Pms1 endonuclease active site and an exonuclease 1-independent mismatch repair pathway.

    Directory of Open Access Journals (Sweden)

    Catherine E Smith

    2013-10-01

    Full Text Available Lynch syndrome (hereditary nonpolypsis colorectal cancer or HNPCC is a common cancer predisposition syndrome. Predisposition to cancer in this syndrome results from increased accumulation of mutations due to defective mismatch repair (MMR caused by a mutation in one of the mismatch repair genes MLH1, MSH2, MSH6 or PMS2/scPMS1. To better understand the function of Mlh1-Pms1 in MMR, we used Saccharomyces cerevisiae to identify six pms1 mutations (pms1-G683E, pms1-C817R, pms1-C848S, pms1-H850R, pms1-H703A and pms1-E707A that were weakly dominant in wild-type cells, which surprisingly caused a strong MMR defect when present on low copy plasmids in an exo1Δ mutant. Molecular modeling showed these mutations caused amino acid substitutions in the metal coordination pocket of the Pms1 endonuclease active site and biochemical studies showed that they inactivated the endonuclease activity. This model of Mlh1-Pms1 suggested that the Mlh1-FERC motif contributes to the endonuclease active site. Consistent with this, the mlh1-E767stp mutation caused both MMR and endonuclease defects similar to those caused by the dominant pms1 mutations whereas mutations affecting the predicted metal coordinating residue Mlh1-C769 had no effect. These studies establish that the Mlh1-Pms1 endonuclease is required for MMR in a previously uncharacterized Exo1-independent MMR pathway.

  15. High Power Wind Generator Designs with Less or No PMs

    DEFF Research Database (Denmark)

    Boldea, Ion; Tutelea, Lucian; Blaabjerg, Frede

    2014-01-01

    wind generator systems with less or no PMs: from classifications based in principle and on gear ratio, through topologies, modeling, design and performance issues, with results from literature and also from authors findings. It is hoped that such a study, focused on the wind generator itself (though......The recent steep increase in high energy permanent magnet (PM) price (above 130$/kg and more) triggered already strong R&D efforts to develop wind generators with less PMs (less weight in NdFeB magnets/kW or the use of ferrite PMs) or fully without PMs. All these by optimizing existing dc excited...... synchronous generators, by doubly-fed (wound rotor) induction and cage induction generators and by introducing new topologies with pertinent costs for high power (MW range) wind energy conversion units. The present overview attempts, based on recent grid specifications, an evaluation of commercial and novel...

  16. The Gaia-ESO Survey: the first abundance determination of the pre-main-sequence cluster Gamma Velorum

    CERN Document Server

    Spina, L; Palla, F; Sacco, G G; Magrini, L; Franciosini, E; Morbidelli, L; Prisinzano, L; Alfaro, E J; Biazzo, K; Frasca, A; Hernandez, J I Gonzalez; Sousa, S G; Adibekyan, V; Delgado-Mena, E; Montes, D; Tabernero, H; Klutsch, A; Gilmore, G; Feltzing, S; Jeffries, R D; Micela, G; Vallenari, A; Bensby, T; Bragaglia, A; Flaccomio, E; Koposov, S; Lanzafame, A C; Pancino, E; Recio-Blanco, A; Smiljanic, R; Costado, M T; Damiani, F; Hill, V; Hourihane, A; Jofre, P; de Laverny, P; Masseron, T; Worley, C

    2014-01-01

    Knowledge of the abundance distribution of star forming regions and young clusters is critical to investigate a variety of issues, from triggered star formation and chemical enrichment by nearby supernova explosions to the ability to form planetary systems.In spite of this, detailed abundance studies are currently available for relatively few regions. In this context, we present the analysis of the metallicity of the Gamma Velorum cluster, based on the products distributed in the first internal release of the Gaia-ESO Survey. The Gamma Velorum candidate members have been observed with FLAMES, using both UVES and Giraffe, depending on the target brightness and spectral type. In order to derive a solid metallicity determination for the cluster, membership of the observed stars must be first assessed. To this aim, we use several membership criteria including radial velocities, surface gravity estimates, and the detection of the photospheric lithium line. Out of the 80 targets observed with UVES, we identify 14 h...

  17. EXPORT : Spectral classification and projected rotational velocities of Vega-type and pre-main sequence stars

    NARCIS (Netherlands)

    Mora, A; Merin, B; Solano, E; Montesinos, B; de Winter, D; Eiroa, C; Ferlet, R; Grady, CA; Miranda, LF; Oudmaijer, RD; Palacios, J; Quirrenbach, A; Harris, AW; Rauer, H; Cameron, A; Deeg, HJ; Garzon, F; Penny, A; Schneider, J; Tsapras, Y; Wesselius, PR

    2001-01-01

    In this paper we present the first comprehensive results extracted from the spectroscopic campaigns carried out by the EXPORT (EXoPlanetary Observational Research Team) consortium. During 1998-1999, EXPORT carried out an intensive observational effort in the framework of the origin and evolution of

  18. Accretion and outflow activity on the late phases of pre-main-sequence evolution. The case of RZ Piscium

    Science.gov (United States)

    Potravnov, I. S.; Mkrtichian, D. E.; Grinin, V. P.; Ilyin, I. V.; Shakhovskoy, D. N.

    2017-03-01

    RZ Psc is an isolated high-latitude post-T Tauri star that demonstrates a UX Ori-type photometric activity. The star shows very weak spectroscopic signatures of accretion, but at the same time possesses the unusual footprints of the wind in Na i D lines. In the present work we investigate new spectroscopic observations of RZ Psc obtained in 2014 during two observation runs. We found variable blueshifted absorption components (BACs) in lines of the other alcali metals, K i 7699 Å and Ca ii IR triplet. We also confirmed the presence of a weak emission component in the Hα line, which allowed us to estimate the mass accretion rate on the star as Ṁ ≤ 7 × 10-12M⊙ yr-1. We could not reveal any clear periodicity in the appearance of BACs in sodium lines. Nevertheless, the exact coincidence of the structure and velocities of the Na i D absorptions observed with the interval of about one year suggests that such a periodicity should exist.

  19. Stellar Activity on the Young Suns of Orion: COUP Observations of K5-7 Pre-Main Sequence Stars

    CERN Document Server

    Wolk, S J; Micela, G; Favata, F; Glassgold, A E; Shang, H; Feigelson, E D

    2005-01-01

    In January 2003, the Chandra Orion Ultradeep Project (COUP) detected about 1400 young stars during a 13.2 day observation of the Orion Nebula Cluster (ONC). This paper studies a well-defined sample of 28 solar-mass COUP sources to characterize the magnetic activity of analogs of the young Sun and thereby to improve understanding of the effects of solar X-rays on the solar nebula during the era of planet formation. We find that active young Suns spend 70% of their time in a characteristic state with relatively constant flux and magnetically confined plasma with temperatures kT_2 = 2.1 * kT_1. During characteristic periods, the 0.5-8 keV X-ray luminosity is about 0.03% of the bolometric luminosity. One or two powerful flares per week with peak luminosities logL_x ~ 30-32 erg/s are typically superposed on this characteristic emission accompanied by heating of the hot plasma component from ~2.4 keV to ~7 keV at the flare peak. The energy distribution of flares superposed on the characteristic emission level follo...

  20. Imaging with SiPMs in noble-gas detectors

    CERN Document Server

    Yahlali, N; González, K; Garcia, A N C; Soriano, A

    2012-01-01

    Silicon photomultipliers (SiPMs) are photosensors widely used for imaging in a variety of high energy and nuclear physics experiments. In noble-gas detectors for double-beta decay and dark matter experiments, SiPMs are attractive photosensors for imaging but they are insensitive to the VUV scintillation emitted by the noble gases (xenon and argon). This difficulty is overcome in the NEXT experiment by coating the SiPMs with tetraphenyl butadiene (TPB) to convert the VUV light into visible light. TPB requires stringent storage and operational conditions to prevent its degradation by environmental agents. The development of UV sensitive SiPMs is thus of utmost interest for experiments using UV light and for noble-gas detectors. It is in particular an important issue for a robust and background free neutrinoless double-beta decay experiment with xenon gas aimed by NEXT. The photon detection efficiency (PDE) of UV-enhanced SiPMs without protective window and with silicon resin window provided by Hamamatsu was det...

  1. Effects of very high radiation on SiPMs

    Energy Technology Data Exchange (ETDEWEB)

    Heering, A., E-mail: Adriaan.Heering@cern.ch [University of Notre Dame, Notre Dame, IN 46556 (United States); Musienko, Yu, E-mail: Iouri.Musienko@cern.ch [University of Notre Dame, Notre Dame, IN 46556 (United States); Instutute for Nuclear Research RAS, pr. 60-letiya Oktyabrya 7a, 117312 Moscow (Russian Federation); Ruchti, R.; Wayne, M. [University of Notre Dame, Notre Dame, IN 46556 (United States); Karneyeu, A.; Postoev, V. [Instutute for Nuclear Research RAS, pr. 60-letiya Oktyabrya 7a, 117312 Moscow (Russian Federation)

    2016-07-11

    During the last 5 years we have successfully completed R&D for the instrumentation of silicon photo multipliers (SiPMs) for the CMS HCAL Phase 1 upgrade in 2018. Much focus was put on radiation damage during these years. For the HCAL we expect a maximum total dose of 10{sup 12} n/cm{sup 2} for a total lifetime integrated luminosity of 3000 fb{sup −1}. Good correlation between cell size and performance with high radiation was found during this R&D. To evaluate the possibility of using the SiPMs in the wider CMS environment we have exposed the current state of the art smallest cell SiPMs to radiation of 6×10{sup 12} p/cm{sup 2} in 62 MeV LIF beam line in 2014 at UCL Belgium and up to 1.3×10{sup 14} p/cm{sup 2} in the CERN PS 23 GeV proton beam in late 2014. The SiPM's main parameters were measured before and after irradiation. Here we report on the effects of noise increase and breakdown voltage shift due to the extremely high dose. - Highlights: • Modeling of noise increase in SiPMs vs. 1 MeV equivalent neutron radiation. • Other effects in SiPMs exposed to very high radiation.

  2. The unusual photometric variability of the PMS star GM Cep

    CERN Document Server

    Semkov, E; Peneva, S; Milanov, T; Stoyanov, K; Stateva, I; Kjurkchieva, D; Dimitrov, D; Radeva, V

    2015-01-01

    Results from UBVRI photometric observations of the pre-main sequence star GM Cep obtained in the period April 2011 - August 2014 are reported in the paper. Presented data are a continuation of our photometric monitoring of the star started in 2008. GM Cep is located in the field of the young open cluster Trumpler 37 and over the past years it has been an object of intense photometric and spectral studies. The star shows a strong photometric variability interpreted as a possible outburst from EXor type in previous studies. Our photometric data for a period of over six years show a large amplitude variability (Delta V ~ 2.3 mag.) and several deep minimums in brightness are observed. The analysis of the collected multicolor photometric data shows the typical of UX Ori variables a color reversal during the minimums in brightness. The observed decreases in brightness have a different shape, and evidences of periodicity are not detected. At the same time, high amplitude rapid variations in brightness typical for th...

  3. The Unusual Photometric Variability of the PMS Star GM Cep

    Science.gov (United States)

    Semkov, E. H.; Ibryamov, S. I.; Peneva, S. P.; Milanov, T. R.; Stoyanov, K. A.; Stateva, I. K.; Kjurkchieva, D. P.; Dimitrov, D. P.; Radeva, V. S.

    2015-03-01

    Results from UBVRI photometric observations of the pre-main sequence star GM Cep obtained in the period 2011 April-2014 August are reported in the paper. Presented data are a continuation of our photometric monitoring of the star started in 2008. GM Cep is located in the field of the young open cluster Trumpler 37 and over the past years it has been an object of intense photometric and spectral studies. The star shows a strong photometric variability interpreted as a possible outburst from EXor type in previous studies. Our photometric data for a period of over six years show a large amplitude variability (ΔV ~ 2.3 mag) and several deep minimums in brightness are observed. The analysis of the collected multicolour photometric data show the typical of UX Ori variables a colour reversal during the minimums in brightness. The observed decreases in brightness have a different shape, and evidences of periodicity are not detected. At the same time, high amplitude rapid variations in brightness typical for the classical T Tauri stars also present on the light curve of GM Cep. The spectrum of GM Cep shows the typical of classical T Tauri stars wide Hα emission line and absorption lines of some metals. We calculate the outer radius of the Hα emitting region as 10.4 ± 0.5 R⊙ and the accretion rate as 1.8 × 10- 7 M⊙ yr- 1.

  4. Lynch Syndrome Caused by Germline PMS2 Mutations

    DEFF Research Database (Denmark)

    Ten Broeke, Sanne W; Brohet, Richard M; Tops, Carli M

    2015-01-01

    . Standardized incidence ratios (SIRs) were calculated to estimate risks for other Lynch syndrome-associated cancers. RESULTS: The cumulative risk (CR) of CRC for male mutation carriers by age 70 years was 19%. The CR among female carriers was 11% for CRC and 12% for EC. The mean age of CRC development was 52......PURPOSE: The clinical consequences of PMS2 germline mutations are poorly understood compared with other Lynch-associated mismatch repair gene (MMR) mutations. The aim of this European cohort study was to define the cancer risk faced by PMS2 mutation carriers. METHODS: Data were collected from 98...... years, and there was a significant difference in mean age of CRC between the probands (mean, 47 years; range, 26 to 68 years) and other family members with a PMS2 mutation (mean, 58 years; range, 31 to 86 years; P

  5. Cryogenic Characterization of FBK RGB-HD SiPMs

    Science.gov (United States)

    Aalseth, C. E.; Acerbi, F.; Agnes, P.; Albuquerque, I. F. M.; Alexander, T.; Alici, A.; Alton, A. K.; Ampudia, P.; Antonioli, P.; Arcelli, S.; Ardito, R.; Arnquist, I. J.; Asner, D. M.; Back, H. O.; Batignani, G.; Bertoldo, E.; Bettarini, S.; Bisogni, M. G.; Bocci, V.; Bondar, A.; Bonfini, G.; Bonivento, W.; Bossa, M.; Bottino, B.; Bunker, R.; Bussino, S.; Buzulutskov, A.; Cadeddu, M.; Cadoni, M.; Caminata, A.; Canci, N.; Candela, A.; Cantini, C.; Caravati, M.; Cariello, M.; Carlini, M.; Carpinelli, M.; Castellani, A.; Catalanotti, S.; Cataudella, V.; Cavalcante, P.; Cereseto, R.; Chen, Y.; Chepurnov, A.; Chiavassa, A.; Cicalò, C.; Cifarelli, L.; Citterio, M.; Cocco, A. G.; Colocci, M.; Corgiolu, S.; Covone, G.; Crivelli, P.; D'Antone, I.; D'Incecco, M.; Da Rocha Rolo, M. D.; Daniel, M.; Davini, S.; De Candia, A.; De Cecco, S.; De Deo, M.; De Filippis, G.; De Guido, G.; De Rosa, G.; Dellacasa, G.; Demontis, P.; Derbin, A. V.; Devoto, A.; Di Eusanio, F.; Di Pietro, G.; Dionisi, C.; Dolgov, A.; Dormia, I.; Dussoni, S.; Empl, A.; Ferri, A.; Filip, C.; Fiorillo, G.; Fomenko, K.; Franco, D.; Froudakis, G. E.; Gabriele, F.; Gabrieli, A.; Galbiati, C.; Garcia Abia, P.; Gendotti, A.; Ghisi, A.; Giagu, S.; Gibertoni, G.; Giganti, C.; Giorgi, M.; Giovanetti, G. K.; Gligan, M. L.; Gola, A.; Gorchakov, O.; Goretti, A. M.; Granato, F.; Grassi, M.; Grate, J. W.; Grigoriev, G. Y.; Gromov, M.; Guan, M.; Guerra, M. B. B.; Guerzoni, M.; Gulino, M.; Haaland, R. K.; Harrop, B.; Hoppe, E. W.; Horikawa, S.; Hosseini, B.; Hughes, D.; Humble, P.; Hungerford, E. V.; Ianni, An.; Jimenez Cabre, S.; Johnson, T. N.; Keeter, K.; Kendziora, C. L.; Kim, S.; Koh, G.; Korablev, D.; Korga, G.; Kubankin, A.; Kugathasan, R.; Kuss, M.; Li, X.; Lissia, M.; Lodi, G. U.; Loer, B.; Longo, G.; Lussana, R.; Luzzi, L.; Ma, Y.; Machado, A. A.; Machulin, I. N.; Mais, L.; Mandarano, A.; Mapelli, L.; Marcante, M.; Margotti, A.; Mari, S. M.; Mariani, M.; Maricic, J.; Marinelli, M.; Marras, D.; Martoff, C. J.; Mascia, M.; Messina, A.; Meyers, P. D.; Milincic, R.; Moggi, A.; Moioli, S.; Monasterio, S.; Monroe, J.; Monte, A.; Morrocchi, M.; Mu, W.; Muratova, V. N.; Murphy, S.; Musico, P.; Nania, R.; Napolitano, J.; Navrer Agasson, A.; Nikulin, I.; Nosov, V.; Nozdrina, A. O.; Nurakhov, N. N.; Oleinik, A.; Oleynikov, V.; Orsini, M.; Ortica, F.; Pagani, L.; Pallavicini, M.; Palmas, S.; Pandola, L.; Pantic, E.; Paoloni, E.; Paternoster, G.; Pavletcov, V.; Pazzona, F.; Pelczar, K.; Pellegrini, L. A.; Pelliccia, N.; Perotti, F.; Perruzza, R.; Piemonte, C.; Pilo, F.; Pocar, A.; Portaluppi, D.; Poudel, S. S.; Pugachev, D. A.; Qian, H.; Radics, B.; Raffaelli, F.; Ragusa, F.; Randle, K.; Razeti, M.; Razeto, A.; Regazzoni, V.; Regenfus, C.; Reinhold, B.; Renshaw, A. L.; Rescigno, M.; Riffard, Q.; Rivetti, A.; Romani, A.; Romero, L.; Rossi, B.; Rossi, N.; Rubbia, A.; Sablone, D.; Salatino, P.; Samoylov, O.; Sands, W.; Sant, M.; Santorelli, R.; Savarese, C.; Scapparone, E.; Schlitzer, B.; Scioli, G.; Sechi, E.; Segreto, E.; Seifert, A.; Semenov, D. A.; Serci, S.; Shchagin, A.; Shekhtman, L.; Shemyakina, E.; Sheshukov, A.; Simeone, M.; Singh, P. N.; Skorokhvatov, M. D.; Smirnov, O.; Sobrero, G.; Sokolov, A.; Sotnikov, A.; Stanford, C.; Suffritti, G. B.; Suvorov, Y.; Tartaglia, R.; Testera, G.; Tonazzo, A.; Tosi, A.; Trinchese, P.; Unzhakov, E. V.; Vacca, A.; Verducci, M.; Viant, T.; Villa, F.; Vishneva, A.; Vogelaar, B.; Wada, M.; Wahl, J.; Walker, S.; Wang, H.; Wang, Y.; Watson, A. W.; Westerdale, S.; Wilhelmi, J.; Williams, R.; Wojcik, M. M.; Wu, S.; Xiang, X.; Xiao, X.; Yang, C.; Ye, Z.; Zappa, F.; Zappalà, G.; Zhu, C.; Zichichi, A.; Zuzel, G.

    2017-09-01

    We report on the cryogenic characterization of Red Green Blue - High Density (RGB-HD) SiPMs developed at Fondazione Bruno Kessler (FBK) as part of the DarkSide program of dark matter searches with liquid argon time projection chambers. A cryogenic setup was used to operate the SiPMs at varying temperatures and a custom data acquisition system and analysis software were used to precisely characterize the primary dark noise, the correlated noise, and the gain of the devices. We demonstrate that FBK RGB-HD SiPMs with low quenching resistance (RGB-HD-LRq) can be operated from 40 K to 300 K with gains in the range 105 to 106 and noise rates at a level of around 1 Hz/mm2.

  6. Cryogenic Characterization of FBK RGB-HD SiPMs

    Energy Technology Data Exchange (ETDEWEB)

    Aalseth, C.E.; et al.

    2017-05-19

    We report on the cryogenic characterization of Red Green Blue - High Density (RGB-HD) SiPMs developed at Fondazione Bruno Kessler (FBK) as part of the DarkSide program of dark matter searches with liquid argon time projection chambers. A dedicated setup was used to measure the primary dark noise, the correlated noise, and the gain of the SiPMs at varying temperatures. A custom-made data acquisition system and analysis software were used to precisely characterize these parameters. We demonstrate that FBK RGB-HD SiPMs with low quenching resistance (RGB-HD-LR$_q$) can be operated from 40 K to 300 K with gains in the range $10^5$ to $10^6$ and noise rates on the order of a few Hz/mm$^2$.

  7. Excitation of Solar-like Oscillations: From PMS to MS Stellar Models

    Indian Academy of Sciences (India)

    R. Samadi; M.-J. Goupil; E. Alecian; F. Baudin; D. Georgobiani; R. Trampedach; R. Stein; Å. Nordlund

    2005-06-01

    The amplitude of solar-like oscillations results from a balance between excitation and damping. As in the sun, the excitation is attributed to turbulent motions that stochastically excite the modes in the uppermost part of the convective zone. We present here a model for the excitation mechanism. Comparisons between modeled amplitudes and helio and stellar seismic constraints are presented and the discrepancies discussed. Finally the possibility and the interest of detecting such stochastically excited modes in pre-main sequence stars are also discussed.

  8. Neutron radiation damage and recovery studies of SiPMs

    Energy Technology Data Exchange (ETDEWEB)

    Tsang, T.; Rao, T.; Stoll, S.; Woody, C.

    2016-12-01

    We characterized the performance of Silicon Photomultipliers (SiPMs) before and after exposure of up to 1012 neutron/cm2 dosage. We show that the typical orders of magnitude increase of dark current upon neutron irradiation can be suppressed by operating it at a lower temperature and single-photoelectron detection capability can be restored. The required operating temperature depends on the dosage received. Furthermore, after high temperature thermal annealing, there is compelling evidence that the extrinsic dark current is lowered by orders of magnitude and single-photon detection performance are to some extent recovered at room temperature. Our experimental findings might have widespread implications for extending the functionality and the useful lifetime of current and future large scale SiPM detectors deployed in ionization radiation environment.

  9. Search for a continuum limit of the PMS phase

    CERN Document Server

    Ayyar, Venkitesh

    2016-01-01

    Previous studies of a simple four-fermion model with staggered fermions in 3D have shown the existence of an exotic quantum critical point, where one may be able to define a continuum limit of the Paramagnetic Strong Phase (or the PMS phase). We believe the existence of the critical point suggests a new mechanism for generating fermion masses. In this work we begin the search for this quantum critical point in 4D by extending the 3D model to 4D. Unlike in 3D, now we do find evidence for an intermediate spontaneously broken phase (FM phase) and are able compute the phase boundaries accurately. In terms of the bare coupling, the width of the intermediate region appears to be quite small.

  10. Neutron radiation damage and recovery studies of SiPMs

    Science.gov (United States)

    Tsang, T.; Rao, T.; Stoll, S.; Woody, C.

    2016-12-01

    We characterized the performance of Silicon Photomultipliers (SiPMs) before and after exposure of up to 1012 neutron/cm2 dosage. We show that the typical orders of magnitude increase of dark current upon neutron irradiation can be suppressed by operating it at a lower temperature and single-photoelectron detection capability can be restored. The required operating temperature depends on the dosage received. Furthermore, after high temperature thermal annealing, there is compelling evidence that the extrinsic dark current is lowered by orders of magnitude and single-photon detection performance are to some extent recovered at room temperature. Our experimental findings might have widespread implications for extending the functionality and the useful lifetime of current and future large scale SiPM detectors deployed in ionization radiation environment.

  11. First wave PMS pilots: a critical analysis of documentation.

    Science.gov (United States)

    Allgar, V; Leese, B; Heywood, P; Walker, R

    2001-01-01

    Contracts and interim local evaluation reports for the 14 first wave PMS pilots in Northern and Yorkshire region were analysed by documentary analysis. Both contracts and reports were found to vary considerably in size and scope. Most contracts contained aims and objectives that were too broad or vague to guide project management and they lacked useful milestones. This made it difficult to identify criteria for measuring success. The local evaluation reports were also of variable quality. It is recommended that contracts should be accompanied by a development plan containing specific objectives, timescale and process for implementation as well as an evaluation strategy. The relative importance of different targets should be agreed and specified at the outset, to allow weighting of partial success, where some objectives, but not others, are achieved. Project milestones would be made explicit and measurable in the development plan. More clarity in contracts and evaluation for future pilots is essential.

  12. Parameters of the preproduction series SiPMs for the CMS HCAL phase I upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Heering, A., E-mail: Adriaan.Heering@cern.ch [University of Notre Dame, Notre Dame, IN 46556 (United States); Musienko, Yu., E-mail: Iouri.Musienko@cern.ch [University of Notre Dame, Notre Dame, IN 46556 (United States); Institute for Nuclear Research RAS, pr. 60-letiya Oktyabrya 7a, 117312 Moscow (Russian Federation); Ruchti, R.; Wayne, M. [University of Notre Dame, Notre Dame, IN 46556 (United States); Karneyeu, A.; Postoev, V. [Institute for Nuclear Research RAS, pr. 60-letiya Oktyabrya 7a, 117312 Moscow (Russian Federation)

    2016-07-11

    In 2012 the HCAL SiPM photo sensor upgrade was approved for the increased luminosity (5*10{sup 34}) of SLHC. The upgrade will replace the current hybrid photodiodes (HPDs) with multi-pixel Geiger-mode avalanche photodiodes, also known as silicon photomultipliers (SiPMs). A key aspect of the upgrade to SiPMs is to add longitudinal segmentation and improve signal to noise to compensate for scintillator radiation damage. After 5 years of R&D with multiple companies we developed custom large dynamic range SiPMs with large PDE and small ENC. To ensure good mechanical alignment and easy handling of the large number of production channels (>20,000) we have developed a custom ceramic package with a very thin 0.3 mm quartz window with Kyocera. Each package holds 8 channels of SiPMs. Here we report on the final SiPM parameters of the 2014 preproduction run from Hamamatsu (HPK) who has produced a series of 175 arrays with a total of 1400 SiPMs. An overview of our QA results and measurements of the photon detection efficiency, spectral response, crosstalk and cell recovery time will be discussed. - Highlights: • Uniformity of large scale SiPM production. • Small cell size SiPMs with high photo detection efficiency. • Fast recovery time SiPMs. • Custom packaging of SiPMs in High Energy Physics experiments.

  13. Electrical characterization and simulation of SiPMs

    Science.gov (United States)

    Scheuch, Florian; Führen, Daniel; Hebbeker, Thomas; Heidemann, Carsten; Merschmeyer, Markus

    2015-07-01

    Silicon Photomultipliers (SiPMs) are versatile and sensitive photon detectors that experience a fast growing variety of use in particle physics and related fields of application. These photo detectors have a very promising photon detection efficiency and are therefore interesting for very low light flux applications such as scintillation and fluorescence light detection. As a semiconductor device the SiPM's gain and time response strongly depend on the operating temperature and voltage. Thus they have to be understood for a proper use of the SiPM. Therefore, accurate electrical simulations of the SiPM's behavior involving electrical readout and front-end electronics help to improve the design of experimental setups, since several different designs can be tested and simulated with a manageable amount of effort. To perform these simulations, a detailed equivalent circuit of the SiPM has to be used containing a set of well-defined parameters. For this purpose, SPICE simulations of SiPMs and readout electronics have been performed. These simulations utilize an improved SiPM model consisting of resistors, capacitances and inductances. The SiPM parameters for these simulations have been determined by measuring the impedance over a wide frequency range while applying a DC voltage in forward direction and various DC voltages from zero up to the SiPM breakdown voltage in order to determine the behavior under operating conditions. The impedance measurements, the electrical model and the resulting simulations are presented. The impact of different setups and the electrical properties of the SiPM is discussed.

  14. Test and characterisation of SiPMs for the MEGII high resolution Timing Counter

    Energy Technology Data Exchange (ETDEWEB)

    Simonetta, M., E-mail: marcello.simonetta@pv.infn.it [INFN-Pavia, Via A. Bassi 6, I-27100 Pavia (Italy); Dipartimento di Fisica dell' Università degli Studi di Pavia, Via A. Bassi 6, I-27100 Pavia (Italy); Biasotti, M. [INFN-Genova, Via Dodecaneso 33, I-16146 Genova (Italy); Dipartimento di Fisica dell' Università di Genova, Via Dodecaneso 33, I-16146 Genova (Italy); Boca, G. [INFN-Pavia, Via A. Bassi 6, I-27100 Pavia (Italy); Dipartimento di Fisica dell' Università degli Studi di Pavia, Via A. Bassi 6, I-27100 Pavia (Italy); Cattaneo, P.W. [INFN-Pavia, Via A. Bassi 6, I-27100 Pavia (Italy); De Gerone, M.; Gatti, F. [INFN-Genova, Via Dodecaneso 33, I-16146 Genova (Italy); Dipartimento di Fisica dell' Università di Genova, Via Dodecaneso 33, I-16146 Genova (Italy); Nardò, R. [INFN-Pavia, Via A. Bassi 6, I-27100 Pavia (Italy); Dipartimento di Fisica dell' Università degli Studi di Pavia, Via A. Bassi 6, I-27100 Pavia (Italy); Nishimura, M. [Department of Physics, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Ootani, W. [ICEPP, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Pizzigoni, G. [INFN-Genova, Via Dodecaneso 33, I-16146 Genova (Italy); Dipartimento di Fisica dell' Università di Genova, Via Dodecaneso 33, I-16146 Genova (Italy); Prata, M.C.; Rossella, M. [INFN-Pavia, Via A. Bassi 6, I-27100 Pavia (Italy); Shibata, N. [Department of Physics, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Uchiyama, Y. [ICEPP, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Yoshida, K. [Department of Physics, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan)

    2016-07-11

    The MEGII Timing Counter will measure the positron time of arrival with a resolution of ~ 30 ps relying on two arrays of scintillator pixels read out by 6144 Silicon Photomultipliers (SiPMs) from AdvanSiD. They are characterised, measuring their breakdown voltage, to assure that the gains of the SiPMs of each pixel are as uniform as possible, to maximise the pixel resolution. Gain measurements have also been performed. - Highlights: • Characterisation of SiPMs for MEG-II Timing Counter is illustrated. • SiPMs breakdown voltage and gain measurement are reported. • The criterion for the choice of each single pixel SiPMs is explained.

  15. The Implementation of Performance Measurement System (PMS: Malaysian Facilities Management (FM Industry

    Directory of Open Access Journals (Sweden)

    Myeda N.E.

    2014-01-01

    Full Text Available Performance Measurement System (PMS is an effective performance measurement tool and technique that is being widely implemented in the global industries. Literature has suggested the significant contributions of its implementation in enhancing the strategic service delivery and performance. However, there is little study undertaken to explore the PMS implementation in Facilities Management (FM industry, particularly focusing on Malaysia. This study explores the PMS practice among FM practitioners and their knowledge in Performance Measurement (PM generally. Findings from this study also proposed the 20 contributing factors that the FM practitioners believed are the barriers in implementing PMS. This research also suggests the future research opportunities in developing a PMS framework that can be used as guidance for FM service delivery in Malaysia.

  16. Deriving reliable fundamental parameters of PMS-rich star clusters affected by differential reddening

    CERN Document Server

    Bonatto, Charles; Lima, Eliade F

    2011-01-01

    We present an approach that improves the search for reliable astrophysical parameters (e.g. age, mass, and distance) of differentially-reddened, pre-main sequence-rich star clusters. It involves simulating conditions related to the early-cluster phases, in particular the differential and foreground reddenings, and internal age spread. Given the loose constraints imposed by these factors, the derivation of parameters based only on photometry may be uncertain, especially for the poorly-populated clusters. We consider a wide range of cluster {\\em (i)} mass and {\\em (ii)} age, and different values of {\\em (iii)} distance modulus, {\\em (iv)} differential and {\\em (v)} foreground reddenings. Photometric errors and their relation with magnitude are also taken into account. We also investigate how the presence of unresolved binaries affect the derived parameters. For each set of {\\em (i)} - {\\em (v)} we build the corresponding model Hess diagram, and compute the root mean squared residual with respect to the observed...

  17. Advances in digital SiPMs and their application in biomedical imaging

    Energy Technology Data Exchange (ETDEWEB)

    Schaart, Dennis R., E-mail: d.r.schaart@tudelft.nl [Delft University of Technology, Faculty of Applied Sciences, Radiation Science and Technology, Mekelweg 15, 2629 JB Delft (Netherlands); Charbon, Edoardo [Delft University of Technology, Faculty of Electrical Engineering, Circuits and Systems, Mekelweg 4, 2628 CD Delft (Netherlands); Frach, Thomas [Philips Digital Photon Counting, Pauwelsstraße 17, 52074 Aachen (Germany); Schulz, Volkmar [Department for Physics of Molecular Imaging Systems, Institute for Experimental Molecular Imaging, RWTH Aachen University, Germany and Philips Research Europe, Aachen (Germany)

    2016-02-11

    Similar to analog silicon photomultipliers (SiPMs), digital SiPMs (dSiPMs) essentially consist of an array of single-photon avalanche photodiodes (SPADs). Instead of a passive quench resistor, however, an active quenching circuit is locally integrated with each SPAD, making the sensor response faster and less sensitive to the gains of the individual SPADs. Moreover, additional circuits for the fully digital acquisition, processing, and readout of optical signals are integrated within the sensor. As a result, dSiPMs offer high photo-detection efficiency, high single-photon time resolution (SPTR), and high uniformity, as well as many practical advantages, such as a very compact form factor, low voltage operation, magnetic field compatibility, high stability of operation, low gain drift, and a high degree of scalability. At the same time, dSiPMs represent a new paradigm in low-level light sensing technology. That is, their fully digital operation makes them true photon counting devices, preserving at least partly the discrete spatio-temporal structure of the information embedded in the optical signal. This means that the operation of dSiPMs can be fully understood only in statistical terms, but also opens up novel possibilities for extracting information from the measured data. So far, the main driver behind the development of dSiPMs has been the detection of scintillation pulses in detectors for time-of-flight (TOF) positron emission tomography (PET). Several types of dSiPM have been developed in recent years. Moreover, first imaging devices based on dSiPMs have been realized by various groups. This review summarizes the main dSiPM concepts and technologies currently under development, provides an overview of the results obtained recently with dSiPMs-based PET and SPECT devices, and presents a critical outlook on the challenges and chances for dSiPMs in future radiomolecular imaging systems.

  18. Fine mapping and candidate gene prediction of the photoperiod and thermo-sensitive genic male sterile gene pms1(t) in rice

    Institute of Scientific and Technical Information of China (English)

    Yuan-fei ZHOU; Xian-yin ZHANG; Qing-zhong XUE

    2011-01-01

    Pei'ai64S, an indica sterile variety with photoperiod and thermo-sensitive genic male sterile (PTGMS) genes, has been widely exploited for commercial seed production for "two-line" hybrid rice in China. One PTGMS gene from Pei'ai64S, pms1(t), was mapped by a strategy of bulked-extreme and recessive-class approach with simple sequence repeat (SSR) and insert and deletion (In-Del) markers. Using linkage analysis for the F2 mapping population consisting of 320 completely male sterile individuals derived from a cross between Pei'ai64S and 93-11 (indica restorer) lines, the pms1(t) gene was delimited to the region between the RM21242 (0.2 cM) and YF11 (0.2 cM) markers on the short arm of chromosome 7. The interval containing the pms1(t) locus, which was co-segregated with RM6776, is a 101.1 kb region based on the Nipponbare rice genome. Fourteen predicted loci were found in this region by the Institute for Genomic Research (TIGR) Genomic Annotation. Based on the function of the locus LOC_Os07g12130 by bioinformatics analysis, it is predicted to encode a protein containing a Myb-like DNA-binding domain, and may process the transcript with thermosensory response. The reverse transcription-polymerase chain reaction (RT-PCR) results revealed that the mRNA levels of LOC_Os07g12130 were altered in different photoperiod and temperature treatments. Thus, the LOC_Os07g12130 locus is the most likely candidate gene for pms1(t). These results may facilitate not only using the molecular marker assisted selection of PTGMS genes, but also cloning of the pms1(t) gene itself.

  19. Effect of sintering temperature and composition on microstructure and properties of PMS-PZT ceramics

    Institute of Scientific and Technical Information of China (English)

    DU Hong-liang; PEI Zhi-bin; LI Zhi-min; LUO Fa; ZHU Dong-mei; ZHOU Wan-cheng; QU Shao-bo

    2006-01-01

    The piezoelectric ceramics xPb(Mn1/3Sb2/3)O3-(1-x)Pb(Zr1/2Ti1/2)O3 (abbreviated as PMS-PZT) were synthesized by traditional ceramics process. The effect of sintering temperature and the amount of Pb(Mn1/3Sb2/3)O3 (abbreviated as PMS) on phase structure,microstructure,piezoelectric and dielectric properties of PMS-PZT ceramics was investigated. The results show that the pure perovskite phase is in all ceramics specimens,the phase structure of PMS-PZT ceramics changes from tetragonal phase to single rhombohedral phase with the increasing amount of PMS. The dielectric constant -r,Curie temperature TC,electromechanical coupling factor kp and piezoelectric constant d33 decrease,whereas the mechanical quality factor Qm and dielectric loss tanδ increase with the increasing amount of PMS in system. The optimum sintering temperature is 1 200-1 250 ℃. It is concluded that the PMS-PZT (x=0.07) ceramics sintered at 1 250 ℃ is suitable for high-power piezoelectric transformer. These properties include -r=674.8,tanδ=0.005 25,kp=0.658,Qm1520,d33=230 pC/N,Tc=275 ℃.

  20. Study of the breakdown voltage of SiPMs

    CERN Document Server

    Chmill, V; Klanner, R; Nitschke, M; Schwandt, J

    2016-01-01

    The breakdown behaviour of SiPMs (Silicon PhotoMultiplier) with pixel sizes of 15$\\times $15, 25$\\times $25, 50$\\times $50, and 100$\\times $100 $\\mu $m$^2$, manufactured by KETEK, has been investigated. From the current-voltage characteristics measured with and without illumination by LED light of 470 nm wavelength, the current-breakdown voltage, $V_I$, and from linear fits of the voltage dependence of the SiPM gain, measured by recording pulse-area spectra, the gain-breakdown voltage, $V_G$, have been obtained. The voltage dependence of the Geiger-breakdown probability was determined from the fraction of zero photoelectron events with LED illumination. By comparing the results to a model calculation, the photodetection-breakdown voltage, $V_{PD}$, has been determined. Within experimental uncertainties, $V_I$ and $V_{PD}$ are equal and independent of pixel size. For $V_G$, a dependence on pixel size is observed. The difference $V_I - V_G$ is about 1 V for the SiPM with 15 $\\mu $m pixels, decreases with pixel ...

  1. Study of the breakdown voltage of SiPMs

    Science.gov (United States)

    Chmill, V.; Garutti, E.; Klanner, R.; Nitschke, M.; Schwandt, J.

    2017-02-01

    The breakdown behaviour of SiPMs (Silicon PhotoMultiplier) with pixel sizes of 15 × 15 , 25 × 25 , 50 × 50, and 100 × 100 μm2, manufactured by KETEK, has been investigated. From the current-voltage characteristics measured with and without illumination by LED light of 470 nm wavelength, the current-breakdown voltage, VI, and from linear fits of the voltage dependence of the SiPM gain, measured by recording pulse-area spectra, the gain-breakdown voltage, VG, have been obtained. The voltage dependence of the Geiger-breakdown probability was determined from the fraction of zero photoelectron events with LED illumination. By comparing the results to a model calculation, the photodetection-breakdown voltage, VPD, has been determined. Within experimental uncertainties, VI and VPD are equal and independent of pixel size. For VG, a dependence on pixel size is observed. The difference VI -VG is about 1 V for the SiPM with 15 μm pixels, decreases with pixel size and is compatible with zero for the SiPM with 100 μm pixels.

  2. The rotation period distributions of 4--10 Myr T Tauri stars in Orion OB1: New constraints on pre-main-sequence angular momentum evolution

    CERN Document Server

    Karim, Md Tanveer; Briceno, Cesar; Vivas, A Katherina; Raetz, Stefanie; Mateu, Cecilia; Downes, Juan Jose; Calvet, Nuria; Hernandez, Jesus; Neuhauser, Ralph; Mugrauer, Markus; Takahashi, Hidenori; Tachihara, Kengo; Chini, Rolf; Cruz-Dias, Gustavo A; Aarnio, Alicia; James, David J; Hackstein, Moritz

    2016-01-01

    Most existing studies of the angular momentum evolution of young stellar populations have focused on the youngest (1-3 Myr) T Tauri stars. In contrast, the angular momentum distributions of older T Tauri stars (4-10 Myr) have been less studied, even though they hold key insight to understanding stellar angular momentum evolution at a time when protoplanetary disks have largely dissipated and when models therefore predict changes in the rotational evolution that can in principle be tested. We present a study of photometric variability among 1,974 confirmed T Tauri members of various sub-regions of the Orion OB1 association, and with ages spanning 4-10 Myr, using optical time-series from three different surveys. For 564 of the stars (~32% of the weak-lined T Tauri stars and ~13% of the classical T Tauri stars in our sample) we detect statistically significant periodic variations which we attribute to the stellar rotation periods, making this one of the largest samples of T Tauri star rotation periods yet publis...

  3. Evidence for Variable, Correlated X-ray and Optical/IR Extinction toward the Nearby, Pre-main Sequence Binary TWA 30

    CERN Document Server

    Principe, David A; Kastner, Joel H; Stelzer, Beate; Alcala, Juan

    2016-01-01

    We present contemporaneous XMM-Newton X-ray and ground-based optical/near-IR spectroscopic observations of the nearby ($D \\approx 42$ pc), low-mass (mid-M) binary system TWA 30A and 30B. The components of this wide (separation $\\sim$3400 AU) binary are notable for their nearly edge-on disk viewing geometries, high levels of variability, and evidence for collimated stellar outflows. We obtained XMM-Newton X-ray observations of TWA 30A and 30B in 2011 June and July, accompanied (respectively) by IRTF SpeX (near-IR) and VLT XSHOOTER (visible/near-IR) spectroscopy obtained within $\\sim$20 hours of the X-ray observations. TWA 30A was detected in both XMM-Newton observations at relatively faint intrinsic X-ray luminosities ($L_{X}$$\\sim$$8\\times10^{27}$ $erg$ $s^{-1}$) compared to stars of similar mass and age . The intrinsic (0.15-2.0 keV) X-ray luminosities measured in 2011 had decreased by a factor 20-100 relative to a 1990 (ROSAT) X-ray detection. TWA 30B was not detected, and we infer an upper limit of ($L_{X}...

  4. The Rotation Period Distributions of 4-10 Myr T Tauri Stars in Orion OB1: New Constraints on Pre-main-sequence Angular Momentum Evolution

    Science.gov (United States)

    Karim, Md Tanveer; Stassun, Keivan G.; Briceño, César; Vivas, A. Katherina; Raetz, Stefanie; Mateu, Cecilia; José Downes, Juan; Calvet, Nuria; Hernández, Jesús; Neuhäuser, Ralph; Mugrauer, Markus; Takahashi, Hidenori; Tachihara, Kengo; Chini, Rolf; Cruz-Dias, Gustavo A.; Aarnio, Alicia; James, David J.; Hackstein, Moritz

    2016-12-01

    Most existing studies of the angular momentum evolution of young stellar populations have focused on the youngest (≲1-3 Myr) T Tauri stars. In contrast, the angular momentum distributions of older T Tauri stars (˜4-10 Myr) have been less studied, even though they hold key insights to understanding stellar angular momentum evolution at a time when protoplanetary disks have largely dissipated and when models therefore predict changes in the rotational evolution that can in principle be tested. We present a study of photometric variability among 1974 confirmed T Tauri members of various subregions of the Orion OB1 association, and with ages spanning 4-10 Myr, using optical time series from three different surveys. For 564 of the stars (˜32% of the weak-lined T Tauri stars and ˜13% of the classical T Tauri stars in our sample) we detect statistically significant periodic variations, which we attribute to the stellar rotation periods, making this one of the largest samples of T Tauri star rotation periods yet published. We observe a clear change in the overall rotation period distributions over the age range 4-10 Myr, with the progressively older subpopulations exhibiting systematically faster rotation. This result is consistent with angular momentum evolution model predictions of an important qualitative change in the stellar rotation periods starting at ˜5 Myr, an age range for which very few observational constraints were previously available.

  5. TIME-SERIES PHOTOMETRY OF STARS IN AND AROUND THE LAGOON NEBULA. I. ROTATION PERIODS OF 290 LOW-MASS PRE-MAIN-SEQUENCE STARS IN NGC 6530

    Energy Technology Data Exchange (ETDEWEB)

    Henderson, Calen B. [Department of Astronomy, Ohio State University, 140 W. 18th Ave., Columbus, OH 43210 (United States); Stassun, Keivan G., E-mail: henderson@astronomy.ohio-state.edu [Department of Physics and Astronomy, Vanderbilt University, VU Station B 1807, Nashville, TN 37235 (United States)

    2012-03-01

    We have conducted a long-term, wide-field, high-cadence photometric monitoring survey of {approx}50,000 stars in the Lagoon Nebula H II region. This first paper presents rotation periods for 290 low-mass stars in NGC 6530, the young cluster illuminating the nebula, and for which we assemble a catalog of infrared and spectroscopic disk indicators, estimated masses and ages, and X-ray luminosities. The distribution of rotation periods we measure is broadly uniform for 0.5 days < P < 10 days; the short-period cutoff corresponds to breakup. We observe no obvious bimodality in the period distribution, but we do find that stars with disk signatures rotate more slowly on average. The stars' X-ray luminosities are roughly flat with rotation period, at the saturation level (log L{sub X} /L{sub bol} Almost-Equal-To -3.3). However, we find a significant positive correlation between L{sub X} /L{sub bol} and corotation radius, suggesting that the observed X-ray luminosities are regulated by centrifugal stripping of the stellar coronae. The period-mass relationship in NGC 6530 is broadly similar to that of the Orion Nebula Cluster (ONC), but the slope of the relationship among the slowest rotators differs from that in the ONC and other young clusters. We show that the slope of the period-mass relationship for the slowest rotators can be used as a proxy for the age of a young cluster, and we argue that NGC 6530 may be slightly younger than the ONC, making it a particularly important touchstone for models of angular momentum evolution in young, low-mass stars.

  6. Time-Series Photometry of Stars in and around the Lagoon Nebula. I. Rotation Periods of 290 Low-Mass Pre-Main-Sequence Stars in NGC 6530

    CERN Document Server

    Henderson, Calen B

    2011-01-01

    We have conducted a long-term, wide-field, high-cadence photometric monitoring survey of ~50,000 stars in the Lagoon Nebula \\ion{H}{2} region. This first paper presents rotation periods for 290 low-mass stars in NGC 6530, the young cluster illuminating the nebula, and for which we assemble a catalog of infrared and spectroscopic disk indicators, estimated masses and ages, and X-ray luminosities. The distribution of rotation periods we measure is broadly uniform for 0.5 < P < 10 d; the short-period cutoff corresponds to breakup. We observe no obvious bimodality in the period distribution, but we do find that stars with disk signatures rotate more slowly on average. The stars' X-ray luminosities are roughly flat with rotation period, at the saturation level ($\\log L_X / L_{\\rm bol} \\approx -3.3$). However, we find a significant positive correlation between $L_X / L_{\\rm bol}$ and co-rotation radius, suggesting that the observed X-ray luminosities are regulated by centrifugal stripping of the stellar coron...

  7. LUMINOSITY DISCREPANCY IN THE EQUAL-MASS, PRE-MAIN-SEQUENCE ECLIPSING BINARY PAR 1802: NON-COEVALITY OR TIDAL HEATING?

    Energy Technology Data Exchange (ETDEWEB)

    Gomez Maqueo Chew, Yilen; Stassun, Keivan G.; Hebb, Leslie [Department of Physics and Astronomy, Vanderbilt University, Nashville, TN 37235 (United States); Prsa, Andrej [Department of Astronomy and Astrophysics, Villanova University, Villanova, PA 19085 (United States); Stempels, Eric [Department of Astronomy and Space Physics, Uppsala University, SE-752 67 Uppsala (Sweden); Barnes, Rory [Department of Astronomy, University of Washington, Seattle, WA 98195 (United States); Heller, Rene [Leibniz-Institut fuer Astrophysik Potsdam (AIP), An der Sternwarte 16, 14482 Potsdam (Germany); Mathieu, Robert D., E-mail: yilen.gomez@vanderbilt.edu [Department of Astronomy, University of Wisconsin-Madison, Madison, WI 53706 (United States)

    2012-01-20

    Parenago 1802, a member of the {approx}1 Myr Orion Nebula Cluster, is a double-lined, detached eclipsing binary in a 4.674 day orbit, with equal-mass components (M{sub 2}/M{sub 1} = 0.985 {+-} 0.029). Here we present extensive VI{sub C} JHK{sub S} light curves (LCs) spanning {approx}15 yr, as well as a Keck/High Resolution Echelle Spectrometer (HIRES) optical spectrum. The LCs evince a third light source that is variable with a period of 0.73 days, and is also manifested in the high-resolution spectrum, strongly indicating the presence of a third star in the system, probably a rapidly rotating Classical T Tauri star. We incorporate this third light into our radial velocity and LC modeling of the eclipsing pair, measuring accurate masses (M{sub 1} = 0.391 {+-} 0.032 and M{sub 2} = 0.385 {+-} 0.032 M{sub Sun }), radii (R{sub 1} = 1.73 {+-} 0.02 and R{sub 2} = 1.62 {+-} 0.02 R{sub Sun }), and temperature ratio (T{sub eff,1}/T{sub eff,2} = 1.0924 {+-} 0.0017). Thus, the radii of the eclipsing stars differ by 6.9% {+-} 0.8%, the temperatures differ by 9.2% {+-} 0.2%, and consequently the luminosities differ by 62% {+-} 3%, despite having masses equal to within 3%. This could be indicative of an age difference of {approx}3 Multiplication-Sign 10{sup 5} yr between the two eclipsing stars, perhaps a vestige of the binary formation history. We find that the eclipsing pair is in an orbit that has not yet fully circularized, e = 0.0166 {+-} 0.003. In addition, we measure the rotation rate of the eclipsing stars to be 4.629 {+-} 0.006 days; they rotate slightly faster than their 4.674 day orbit. The non-zero eccentricity and super-synchronous rotation suggest that the eclipsing pair should be tidally interacting, so we calculate the tidal history of the system according to different tidal evolution theories. We find that tidal heating effects can explain the observed luminosity difference of the eclipsing pair, providing an alternative to the previously suggested age difference.

  8. Variability of Disk Emission in Pre-Main Sequence and Related Stars. II. Variability in the Gas and Dust Emission of the Herbig Fe Star SAO 206462

    CERN Document Server

    Sitko, Michael L; Kimes, Robin L; Beerman, Lori C; Martus, Cameron; Lynch, David K; Russell, Ray W; Grady, Carol A; Schneider, Glenn; Lisse, Carey M; Nuth, Joseph A; Cure, Michel; Henden, Arne A; Kraus, Stefan; Motta, Veronica; Tamura, Motohide; Hornbeck, Jeremy; Williger, Gerard M; Fugazza, Dino

    2011-01-01

    We present thirteen epochs of near-infrared (0.8-5 micron) spectroscopic observations of the pre-transitional, "gapped" disk system in SAO 206462 (=HD 135344B). In all, six gas emission lines (including Br gamma, Pa beta, and the 0.8446 micron line of O I) along with continuum measurements made near the standard J, H, K, and L photometric bands were measured. A mass accretion rate of approximately 2 x 10^-8 solar masses per year was derived from the Br gamma and Pa beta lines. However, the fluxes of these lines varied by a factor of over two during the course of a few months. The continuum also varied, but by only ~30%, and even decreased at a time when the gas emission was increasing. The H I line at 1.083 microns was also found to vary in a manner inconsistent with that of either the hydrogen lines or the dust. Both the gas and dust variabilities indicate significant changes in the region of the inner gas and the inner dust belt that may be common to many young disk systems. If planets are responsible for d...

  9. Variability of Disk Emission in Pre-Main Sequence and Related Stars. III. Exploring Structural Changes in the Pre-transitional Disk in HD 169142

    CERN Document Server

    Wagner, Kevin R; Grady, Carol A; Whitney, Barbara A; Swearingen, Jeremy R; Champney, Elizabeth H; Johnson, Alexa N; Werren, Chelsea; Russell, Ray W; Schneider, Glenn H; Momose, Munetake; Muto, Takayuki; Inoue, Akio K; Lauroesch, James T; Brown, Alexander; Fukagawa, Misato; Currie, Thayne M; Hornbeck, Jeremy; Wisniewski, John P; Woodgate, Bruce E

    2014-01-01

    We present near-IR and far-UV observations of the pre-transitional (gapped) disk in HD 169142 using NASA's Infrared Telescope Facility and Hubble Space Telescope. The combination of our data along with existing data sets into the broadband spectral energy distribution reveals variability of up to 45% between ~1.5-10 {\\mu}m over a maximum timescale of 10 years. All observations known to us separate into two distinct states corresponding to a high near-IR state in the pre-2000 epoch and a low state in the post-2000 epoch, indicating activity within the <1 AU region of the disk. Through analysis of the Pa {\\beta} and Br {\\gamma} lines in our data we derive a mass accretion rate in May 2013 of (1.5 - 2.7) x 10^-9 Msun/yr. We present a theoretical modeling analysis of the disk in HD 169142 using Monte-Carlo radiative transfer simulation software to explore the conditions and perhaps signs of planetary formation in our collection of 24 years of observations. We find that shifting the outer edge (r = 0.3 AU) of t...

  10. Evidence for variable, correlated X-ray and optical/IR extinction towards the nearby, pre-main-sequence binary TWA 30

    Science.gov (United States)

    Principe, David A.; Sacco, G.; Kastner, J. H.; Stelzer, B.; Alcalá, J. M.

    2016-06-01

    We present contemporaneous XMM-Newton X-ray and ground-based optical/near-IR spectroscopic observations of the nearby (D ≈ 42 pc), low-mass (mid-M) binary system TWA 30A and 30B. The components of this wide (separation ˜3400 au) binary are notable for their nearly edge-on disc viewing geometries, high levels of variability, and evidence for collimated stellar outflows. We obtained XMM-Newton X-ray observations of TWA 30A and 30B in 2011 June and July, accompanied (respectively) by Infrared Telescope Facility SpeX (near-IR) and VLT XSHOOTER (visible/near-IR) spectroscopy obtained within ˜20 h of the X-ray observations. TWA 30A was detected in both XMM-Newton observations at relatively faint intrinsic X-ray luminosities (LX ˜ 8 × 1027 erg s-1) compared to stars of similar mass and age. The intrinsic (0.15-2.0 keV) X-ray luminosities measured in 2011 had decreased by a factor 20-100 relative to a 1990 (ROSAT) X-ray detection. TWA 30B was not detected, and we infer an upper limit on its X-ray Luminosity of LX ≲ 3.0 × 1027 erg s-1. We measured a decrease in visual extinction towards TWA 30A (from AV ≈ 14.9 to AV ≈ 4.7) between the two 2011 observing epochs, and we find evidence for a corresponding significant decrease in X-ray absorbing column (NH). The apparent correlated change in AV and NH is suggestive of variable obscuration of the stellar photosphere by disc material composed of both gas and dust. However, in both observations, the inferred NH to AV ratio is lower than that typical of the interstellar medium, suggesting that the disc is either depleted of gas or is deficient in metals in the gas phase.

  11. Variability of Disk Emission in Pre-main Sequence and Related Stars. V. Changes in the Innermost Disk Structure of the Herbig AE Star HD 31648 = MWC 480

    Science.gov (United States)

    Fernandes, Rachel; Long, Zachary; Sitko, Michael L.; Grady, C. A.; Kusakabe, Nobuhiko

    2017-01-01

    We present five epochs of near IR observations of the protoplanetary disk around HD 31648 (MWC 480). A mass accretion rate of approximately 1.1×10-7 Msun/year was derived from Brγ and Paβ lines. The spectral energy distribution (SED) reveals a variability of about 30% between 1.5 and 10 microns. We present the theoretical modeling analysis of the disk in HD 31648 using Monte-Carlo Radiation Transfer Code (MRTC). We find that varying the height of the inner rim successfully produces a shift in the NIR flux.

  12. Cryogenic Characterization of the FBK NUV-HD SiPMs

    CERN Document Server

    Acerbi, Fabio; Ferri, Alessandro; Galbiati, Cristiano; Giovanetti, Graham; Gola, Alberto; Korga, George; Mandarano, Andrea; Marcante, Marco; Paternoster, Giovanni; Piemonte, Claudio; Razeto, Alessandro; Regazzoni, Veronica; Sablone, Davide; Savarese, Claudio; Zappalá, Gaetano; Zorzi, Nicola

    2016-01-01

    We report on the characterization of the NUV-HD SiPMs developed at FBK at cryogenic temperature. A dedicated setup was built to measure the primary dark noise and correlated noises of the SiPMs between 40 and 300 K. Moreover a specific analysis program in conjunction with an ad-hoc data acquisition system were developed to allow the precise characterization of these parameters, some of which can vary up to 7 orders of magnitude between room temperature and 40 K. We proved that it is possible to operate the FBK NUV-HD SiPMs at temperatures lower than 100 K with a dark noise below 0.01 cps/mm$^2$ and total correlated noise below 35% at 6 V of over-voltage. These results are relevant for the development of future cryogenic particle detector based with SiPMs as photosensors.

  13. Characterization of FBK SiPMs under illumination with very fast light pulses

    Energy Technology Data Exchange (ETDEWEB)

    Tarolli, A., E-mail: tarolli@fbk.e [Fondazione Bruno Kessler (FBK), Trento (Italy); Dalla Betta, G.-F. [University of Trento and INFN, Trento (Italy); Melchiorri, M.; Piazza, A.; Pancheri, L.; Piemonte, C.; Zorzi, N. [Fondazione Bruno Kessler (FBK), Trento (Italy)

    2010-05-21

    A characterization of the response of SiPMs and SPADs produced at FBK-IRST Trento stimulated with fast laser pulses is presented. The tests were aimed at studying both the intrinsic timing proprieties (of SiPMs and SPADs) using the time-correlated single-photon counting technique and the dynamic range (of SiPMs). Measurements were carried out on devices with different cell size, namely, from 40x40 to 100x100 {mu}m{sup 2}. Concerning the timing resolution, all the devices exhibit a value less than 150 psec FWHM. The dynamic range of SiPMs shows a response linearity which is in line with the theory describing these devices.

  14. PMS as a process of negotiation: women's experience and management of premenstrual distress.

    Science.gov (United States)

    Ussher, Jane M; Perz, Janette

    2013-01-01

    The absence of reports of premenstrual syndrome (PMS) in contexts such as China, Hong Kong, and India has led to the conclusion that PMS is a culture-bound syndrome. This qualitative study examines whether is it possible for women in a Western cultural context to negotiate negative premenstrual change in order to effectively avoid or reduce premenstrual distress. Sixty women who self-defined as a 'PMS sufferer' took part in one-to-one interviews, which were analysed using theoretical thematic analysis from a material-discursive-intrapsychic (MDI) perspective. Three major themes were consistently identified across relationship type and context, reflecting women's strategies of premenstrual self-regulation and coping: 'Self-monitoring and awareness: recognition and acceptance of premenstrual change'; 'Coping through self-regulation of premenstrual distress', including: 'avoidance of stress and conflict', 'escaping relational demands and responsibilities', and 'care of the self'; and 'Coping as an inter-subjective experience'. These findings challenge the view of PMS as a fixed unitary syndrome, suggesting that premenstrual change is an ongoing process of negotiation, in which women are agentic subjects, not passive 'PMS sufferers'. This has implications for therapists working with women reporting moderate-severe PMS, suggesting that the reframing of 'symptoms' as normal change, behavioural coping strategies, and self-monitoring, can effectively reduce premenstrual distress.

  15. Seismic diagnostics for transport of angular momentum in stars 1. Rotational splittings from the PMS to the RGB

    CERN Document Server

    Marques, J P; Lebreton, Y; Talon, S; Palacios, A; Belkacem, K; Ouazzani, R -M; Mosser, B; Moya, A; Morel, P; Pichon, B; Mathis, S; Zahn, J -P; Turck-Chièze, S; Nghiem, P A P

    2012-01-01

    Rotational splittings are currently measured for several main sequence stars and a large number of red giants with the space mission Kepler. This will provide stringent constraints on rotation profiles. Our aim is to obtain seismic constraints on the internal transport and surface loss of angular momentum of oscillating solar-like stars. To this end, we study the evolution of rotational splittings from the pre-main sequence to the red-giant branch for stochastically excited oscillation modes. We modified the evolutionary code CESAM2K to take rotationally induced transport in radiative zones into account. Linear rotational splittings were computed for a sequence of $1.3 M_{\\odot}$ models. Rotation profiles were derived from our evolutionary models and eigenfunctions from linear adiabatic oscillation calculations. We find that transport by meridional circulation and shear turbulence yields far too high a core rotation rate for red-giant models compared with recent seismic observations. We discuss several uncert...

  16. Implementation of the Performance Management System (PMS) in Senior Secondary Schools in Botswana: An Investigation of Senior Management Team's Expected Benefits of the PMS

    Science.gov (United States)

    Bulawa, Philip

    2012-01-01

    Different forms of the performance management system have been implemented in many countries for some years. As in other countries, in 1999 the government of Botswana took a decision to implement a performance management system (PMS) across the entire public service including schools. The government explained the purpose for which this reform was…

  17. Chronic periodontitis as an etiology of sleep disturbances and premenstrual syndrome (PMS

    Directory of Open Access Journals (Sweden)

    Haryono Utomo

    2007-03-01

    Full Text Available It is obvious that sleep disturbances may induced by acute pulpal or periodontal pain. Other causes of sleep disturbances which also termed as sleep dysfunction, or insomnia, according to the patient has to be treated by physician. Nevertheless, in a case report, surprisingly, periodontal treatment relieved sleep disturbances and premenstrual syndrome (PMS. Coincidentally, women also more vulnerable to sleep disturbances and periodontal disease. It is also interesting that the exact etiology of PMS is still unknown, and 80% women who suffered from PMS also experience sleep disturbances. Recently, there has been increasing numbers of literatures and evidence-based cases linking periodontal disease to systemic diseases. However, systemic effects of periodontal disease that lead to PMS which associated with sleep disturbances are rarely discussed. Several mechanisms had been proposed to involve in these symptoms: female sexual hormonal imbalance, stimulation of the hypothalamic-pituitary-adrenal axis (HPA-axis and neurogenic switching mechanism. In addition, as estrogen makes women more susceptible to stress, it worsen the symptoms. The glucocorticoid hormones synthesized upon stimulation of the HPA-axis, either by stress or pro-inflammatory cytokines, may disrupt the sleep-wake cycle; and also create estrogen dominance. The aim of this study is to propose the etiopathogenesis of PMS which associated with sleep disturbances that may be related to chronic periodontitis. Since in this case report scaling and curettage resulted in the disappearing of PMS and sleep disturbances; the conclusion is that chronic periodontal disease may act as one of the etiologies of PMS and sleep disturbance.

  18. Comprehensive population-wide analysis of Lynch syndrome in Iceland reveals founder mutations in MSH6 and PMS2

    DEFF Research Database (Denmark)

    Haraldsdottir, Sigurdis; Rafnar, Thorunn; Frankel, Wendy L

    2017-01-01

    Lynch syndrome, caused by germline mutations in the mismatch repair genes, is associated with increased cancer risk. Here using a large whole-genome sequencing data bank, cancer registry and colorectal tumour bank we determine the prevalence of Lynch syndrome, associated cancer risks...... hypermethylation or mutations in the mismatch repair genes. The population prevalence of Lynch syndrome is 0.442%. We discover a translocation disrupting MLH1 and three mutations in MSH6 and PMS2 that increase endometrial, colorectal, brain and ovarian cancer risk. We find thirteen mismatch repair variants...... and pathogenicity of several variants in the Icelandic population. We use colorectal cancer samples from 1,182 patients diagnosed between 2000-2009. One-hundred and thirty-two (11.2%) tumours are mismatch repair deficient per immunohistochemistry. Twenty-one (1.8%) have Lynch syndrome while 106 (9.0%) have somatic...

  19. Parameters of the preproduction series SiPMs for the CMS HCAL phase I upgrade

    Science.gov (United States)

    Heering, A.; Musienko, Yu.; Ruchti, R.; Wayne, M.; Karneyeu, A.; Postoev, V.

    2016-07-01

    In 2012 the HCAL SiPM photo sensor upgrade was approved for the increased luminosity (5*1034) of SLHC. The upgrade will replace the current hybrid photodiodes (HPDs) with multi-pixel Geiger-mode avalanche photodiodes, also known as silicon photomultipliers (SiPMs). A key aspect of the upgrade to SiPMs is to add longitudinal segmentation and improve signal to noise to compensate for scintillator radiation damage. After 5 years of R&D with multiple companies we developed custom large dynamic range SiPMs with large PDE and small ENC. To ensure good mechanical alignment and easy handling of the large number of production channels (>20,000) we have developed a custom ceramic package with a very thin 0.3 mm quartz window with Kyocera. Each package holds 8 channels of SiPMs. Here we report on the final SiPM parameters of the 2014 preproduction run from Hamamatsu (HPK) who has produced a series of 175 arrays with a total of 1400 SiPMs. An overview of our QA results and measurements of the photon detection efficiency, spectral response, crosstalk and cell recovery time will be discussed.

  20. PREMENSTRUAL SYNDROME SYMPTOMS (PMS AND PREVALENCE AMONG UNIVERSITY STUDENTS IN KARACHI, PAKISTAN

    Directory of Open Access Journals (Sweden)

    Zehra Sitwat

    2013-04-01

    Full Text Available A cross-sectional study was designed to investigate the frequency of PMS, on 520 subjects selected from University of Karachi (mean age 20±1.94.The PMS and menstrual cycle data of individuals were collected from prism calendar and symptom-thermal chart for three consecutive cycles. Based on the observations, all subjects were grouped as control (208 and PMS patients (312. The frequency (60% with symptoms include irritability (71.05%, fatigue (86.84%, and bowel constipation (36.76% and loose bowel (17.65%, appetite up (42.65%, and appetite down (51.47%.Breast tenderness (67.65%, abdominal blotting (47.06%, aggressiveness (29.41%, depression (13.24%, and insomnia (14.71%, labile mood (5.88%, and anger (7.35%. Elevated irritability and breast tenderness were observed in age group (19-24 years i.e. 92% and 82% respectively with p<0.001. The present study identified a pattern non-similar to the typical PMS pattern of the Western populations. The typical socio-cultural habitat of Pakistani population, may have led to the evolution of a different pattern of PMS.

  1. The PMS star V1184 Tau (CB 34V) at the end of prolonged eclipse

    CERN Document Server

    Semkov, E H; Ibryamov, S I

    2015-01-01

    V1184 Tau (CB 34V) lies in the field of the Bok globule CB 34 and was discovered as a large amplitude variable in 1993. According to the first hypothesis of the variability of the star, it is a FU Orionis candidate erupted between 1951 and 1993. During subsequent observations, the star manifests large amplitude variability interpreted as obscuration from circumstellar clouds of dust. We included V1184 Tau (CB 34V) in our target list of highly variable pre-main-sequence stars to determine the reasons for the variations in the brightness of this object. Data from BVRI photometric observations of the young stellar object V1184 Tau, obtained in the period 2008-2015, are presented in the paper. These data are a continuation of our optical photometric monitoring of the star began in 2000 and continuing to date. The photometric observations of V1184 Tau were performed in two observatories with two medium-sized and two small telescopes. Our results indicate that during periods of maximum light the star shows characte...

  2. Origin and Evolution of Magnetic Field in PMS Stars: Influence of Rotation and Structural Changes

    Science.gov (United States)

    Emeriau-Viard, Constance; Brun, Allan Sacha

    2017-09-01

    During stellar evolution, especially in the pre-main-sequence phase, stellar structure and rotation evolve significantly, causing major changes in the dynamics and global flows of the star. We wish to assess the consequences of these changes on stellar dynamo, internal magnetic field topology, and activity level. To do so, we have performed a series of 3D HD and MHD simulations with the ASH code. We choose five different models characterized by the radius of their radiative zone following an evolutionary track computed by a 1D stellar evolution code. These models characterized stellar evolution from 1 to 50 Myr. By introducing a seed magnetic field in the fully convective model and spreading its evolved state through all four remaining cases, we observe systematic variations in the dynamical properties and magnetic field amplitude and topology of the models. The five MHD simulations develop a strong dynamo field that can reach an equipartition state between the kinetic and magnetic energies and even superequipartition levels in the faster-rotating cases. We find that the magnetic field amplitude increases as it evolves toward the zero-age main sequence. Moreover, the magnetic field topology becomes more complex, with a decreasing axisymmetric component and a nonaxisymmetric one becoming predominant. The dipolar components decrease as the rotation rate and the size of the radiative core increase. The magnetic fields possess a mixed poloidal-toroidal topology with no obvious dominant component. Moreover, the relaxation of the vestige dynamo magnetic field within the radiative core is found to satisfy MHD stability criteria. Hence, it does not experience a global reconfiguration but slowly relaxes by retaining its mixed stable poloidal-toroidal topology.

  3. 23 CFR 970.208 - Federal lands pavement management system (PMS).

    Science.gov (United States)

    2010-04-01

    ..., surface type, or other criteria the NPS deems appropriate. (c) The PMS shall be designed to fit the NPS... type, functional classification, and shoulder information; (ii) A history of project dates and types of... long term budget forecasting; and (E) Recommends optimal allocation of limited funds by developing a...

  4. 23 CFR 973.208 - Indian lands pavement management system (PMS).

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Indian lands pavement management system (PMS). 973.208... HIGHWAYS MANAGEMENT SYSTEMS PERTAINING TO THE BUREAU OF INDIAN AFFAIRS AND THE INDIAN RESERVATION ROADS PROGRAM Bureau of Indian Affairs Management Systems § 973.208 Indian lands pavement management system...

  5. On the characterisation of SiPMs from pulse-height spectra

    CERN Document Server

    Chmill, V; Klanner, R; Nitschke, M; Schwandt, J

    2016-01-01

    Methods are developed, which use the pulse-height spectra of SiPMs measured in the dark and illuminated by pulsed light, to determine the pulse shape, the dark-count rate, the gain, the average number of photons initiating a Geiger discharge, the probabilities for prompt cross-talk and after-pulses, as well as the electronics noise and the gain fluctuations between and in pixels. The entire pulse-height spectra, including the background regions in-between the peaks corresponding to different number of Geiger discharges, are described by single functions. As a demonstration, the model is used to characterise a KETEK SiPM with 4382 pixels of 15 \\mu m x 15 \\mu m area for voltages between 2.5 and 8 V above the breakdown voltage at 20{\\deg}C. The results are compared to other methods of characterising SiPMs. Finally, examples are given, how the complete description of the pulse-eight spectra can be used to optimise the operating voltage of SiPMs, and a method for an in-situ calibration and monitoring of SiPMs, sui...

  6. Development of high performance readout ASICs for silicon photomultipliers (SiPMs)

    Energy Technology Data Exchange (ETDEWEB)

    Shen, Wei

    2012-07-24

    Silicon Photomultipliers (SiPMs) are novel kind of solid state photon detectors with extremely high photon detection resolution. They are composed of hundreds or thousands of avalanche photon diode pixels connected in parallel. These avalanche photon diodes are operated in Geiger Mode. SiPMs have the same magnitude of multiplication gain compared to the conventional photomultipliers (PMTs). Moreover, they have a lot of advantages such as compactness, relatively low bias voltage and magnetic field immunity etc. Special readout electronics are required to preserve the high performance of the detector. KLauS and STiC are two CMOS ASIC chips designed in particular for SiPMs. KLauS is used for SiPM charge readout applications. Since SiPMs have a much larger detector capacitance compared to other solid state photon detectors such as PIN diodes and APDs, a few special techniques are used inside the chip to make sure a descent signal to noise ratio for pixel charge signal can be obtained. STiC is a chip dedicated to SiPM time-of-flight applications. High bandwidth and low jitter design schemes are mandatory for such applications where time jitter less than tens of picoseconds is required. Design schemes and error analysis as well as measurement results are presented in the thesis.

  7. A frame-shift mutation of PMS2 is a widespread cause of Lynch syndrome

    DEFF Research Database (Denmark)

    Clendenning, Mark; Senter, Leigha; Hampel, Heather;

    2008-01-01

    on immunohistochemical analysis. RESULTS: We have identified a frequently occurring frame-shift mutation (c.736_741del6ins11) in 12 ostensibly unrelated Lynch syndrome patients (20% of patients we have identified with a deleterious mutation in PMS2, n=61). These individuals all display the rare allele (population...

  8. 23 CFR 971.208 - Federal lands pavement management system (PMS).

    Science.gov (United States)

    2010-04-01

    ...; and (iii) An investment analysis that: (A) Identifies alternative strategies to improve pavement....nsf. (c) The PMS may be utilized at various levels of technical complexity depending on the nature of... other appropriate associated facilities in the inventory or any subset. The minimum analyses shall...

  9. Isolated Loss of PMS2 Immunohistochemical Expression is Frequently Caused by Heterogenous MLH1 Promoter Hypermethylation in Lynch Syndrome Screening for Endometrial Cancer Patients.

    Science.gov (United States)

    Kato, Aya; Sato, Naoki; Sugawara, Tae; Takahashi, Kazue; Kito, Masahiko; Makino, Kenichi; Sato, Toshiharu; Shimizu, Dai; Shirasawa, Hiromistu; Miura, Hiroshi; Sato, Wataru; Kumazawa, Yukiyo; Sato, Akira; Kumagai, Jin; Terada, Yukihiro

    2016-06-01

    Lynch syndrome (LS) is an autosomal-dominant inherited disorder mainly caused by a germline mutation in the DNA mismatch repair (MMR) genes (MLH1, MSH2, MSH6, and PMS2) and is associated with increased risk for various cancers, particularly colorectal cancer and endometrial cancer (EC). Women with LS account for 2% to 6% of EC patients; it is clinically important to identify LS in such individuals for predicting and/or preventing additional LS-associated cancers. PMS2 germline mutation (PMS2-LS) is the rarest contribution to LS etiology among the 4 LS-associated MMR germline mutations, and its detection is complicated. Therefore, prudent screening for PMS2-LS is important as it leads to an efficient LS identification strategy. Immunohistochemistry is recommended as a screening method for LS in EC. Isolated loss of PMS2 (IL-PMS2) expression is caused not only by PMS2-LS but also by MLH1 germline mutation or MLH1 promoter hypermethylation (MLH-PHM). This study aimed to determine the association between MLH1-PHM and IL-PMS2 to avoid inappropriate genetic analysis. We performed MLH1 methylation analysis and MLH1/PMS2 germline mutation testing on the IL-PMS2 cases. By performing MMR-immunohistochemistry on 360 unselected ECs, we could select 8 (2.2%) cases as IL-PMS2. Heterogenous MLH1 staining and MLH1-PHM were detected in 4 of 8 (50%) IL-PMS2 tumors. Of the 5 IL-PMS2 patients who underwent genetic analysis, 1 had PMS2 germline mutation with normal MLH1 expression (without MLH1-PHM), and no MLH1 germline mutation was detected. We suggest that MLH1 promoter methylation analysis for IL-PMS2 EC should be performed to exclude sporadic cases before further PMS2 genetic testing.

  10. Radiation Hardness Tests of SiPMs for the JLab Hall D Barrel Calorimeter

    CERN Document Server

    Qiang, Yi; Barbosa, Fernando; Smith, Elton

    2012-01-01

    We report on the measurement of the neutron radiation hardness of silicon photomultipliers (SiPMs) manufactured by Hamamatsu Corporation in Japan and SensL in Ireland. Samples from both companies were irradiated by neutrons created by a 1 GeV electron beam hitting a thin lead target at Jefferson Lab Hall A. More tests regarding the temperature dependence of the neutron radiation damage and self-annealing were performed on Hamamatsu SiPMs using a calibrated Am-Be neutron source from the Jefferson Lab Radiation Control group. As the results of all irradiation, both dark current and dark noise increase linearly as a function of the 1 MeV equivalent neutron fluence and a temperature dependent self-annealing effect is observed together with the radiation damage.

  11. SiPMs coated with TPB : coating protocol and characterization for NEXT

    CERN Document Server

    Álvarez, V; Ball, M; Batallé, M; Bayarri, J; Borges, F I G; Bolink, H; Brine, H; Cárcel, S; Carmona, J M; Castel, J; Catalá, J M; Cebrián, S; Cervera, A; Chan, D; Conde, C A N; Dafni, T; Dias, T H V T; Díaz, J; Esteve, R; Evtoukhovitch, P; Ferrando, J; Fernandes, L M P; Ferrario, P; Ferreira, A L; Ferrer-Ribas, E; Freitas, E D C; García, S A; Gil, A; Giomataris, I; Goldschmidt, A; Gómez, E; Gómez, H; Gómez-Cadenas, J J; González, K; Gutiérrez, R M; Hauptman, J; Hernando-Morata, J A; Herrera, D C; Herrero, V; Iguaz, F J; Irastorza, I G; Kalinnikov, V; Labarga, L; Liubarsky, I; Lopes, J A M; Lorca, D; Losada, M; Luzón, G; Marí, A; Martin-Albo, J; Méndez, A M; Miller, T; Moisenko, A; Monrabal, F; Monteiro, C M B; Monzó, J M; Mora, F J; Vidal, J Muñoz; da Luz, H Natal; Navarro, G; Nebot, M; Nygren, D; Oliveira, C A B; Palma, R; Aparicio, J L Pérez; Pérez, J; Radicioni, E; Quinto, M; Renner, J; Ripoll, L; Rodriguez, A; Rodriguez, J; Santos, F P; Santos, J M F dos; Seguí, L; Serra, L; Shuman, D; Sofka, C; Sorel, M; Soriano, A; Spieler, H; Toledo, J F; Collell, J Torrent; Tomás, A; Tsamalaidze, Z; Vázquez, D; Velicheva, E; Veloso, J F C A; Villar, J A; Webb, R; Weber, T; White, J T; Yahlali, N

    2012-01-01

    Silicon photomultipliers (SiPM) are the photon detectors chosen for the tracking readout in NEXT, a neutrinoless {\\beta}{\\beta} decay experiment which uses a high pressure gaseous xenon time projection chamber (TPC). The reconstruction of event track and topology in this gaseous detector is a key handle for background rejection. Among the commercially available sensors that can be used for tracking, SiPMs offer important advantages, mainly high gain, ruggedness, cost-effectiveness and radio-purity. Their main drawback, however, is their non sensitivity in the emission spectrum of the xenon scintillation (peak at 175 nm). This is overcome by coating these sensors with the organic wavelength shifter tetraphenyl butadienne (TPB). In this paper we describe the protocol developed for coating the SiPMs with TPB and the measurements performed for characterizing the coatings as well as the performance of the coated sensors in the UV-VUV range.

  12. Long-term photometric behavior of the PMS stars V977 Cep and V982 Cep in the vicinity of NGC 7129

    CERN Document Server

    Ibryamov, Sunay I; Milanov, Teodor R; Peneva, Stoyanka P

    2016-01-01

    Long-term BVRI photometric light curves of the pre-main sequence stars V977 Cep and V982 Cep during the period from 2000 October to 2016 August are presented. The stars are located in the vicinity of the reflection nebula NGC 7129. Our photometric data shows that both stars exhibit strong photometric variability in all optical passbands, which is typical for Classical T Tauri stars. Using our observational data we defined the reasons for the observed brightness variations. In the case of V977 Cep we registered previously unknown periodicity in its light curve.

  13. Mismatch repair genes (hMLH1, hPMS1, hPMS2, GTBP/hMSH6, hMSH2) in the pathogenesis of hepatocellular carcinoma

    Institute of Scientific and Technical Information of China (English)

    Abdel-Rahman N. Zekri; Gelane M. Sabry; Abeer A. Bahnassy; Kamal A. Shalaby; Sabrin A. Abdel-Wahabh; Serag Zakaria

    2005-01-01

    AIM: DNA misrnatch repair (MMR) is an impotent mechanism for maintaining fidelity of genomic DNA. Abnormalities in one or more MMR genes are implicated in the development of many cancers. We investigated the role of expression of MMR genes (hMLH1, hPMS1, hPMS2, GTBP/hMSH6, hMSH2) in hepatocellular carcinogenesis. METHODS: We evaluated the expression level of MMR genes in 33 hepatocellular carcinoma (HCC) cases using the multiplex reverse transcription (RT) PCR assays, as well as in 16 cases of normal adjacent hepatic tissues. Β-actin gene was used as an internal control and calibrator for quantification of gene expression. RESULTS: Out of the 33 studied cases, 25 were HCV positiveand 30 (90.9%) showed reduced expression in one or more of the studied MMR genes. Reduced expression was found in hMSH2 (71.9%), hMLH1 (53.3%), GTBP (51.1%), hPMS2 (33.3%) and hPMS1 (6%). A significant correlation was found between reduced expression of hPMS2(P= 0.0069) and GTBP(P= 0.0034), hPMS2and non-cirrhosis (P= 0.0197),hMLH1 and high grade. On the other hand, 57.1%, 50%, 20%, 18.8%, and 6% of the normal tissues distant to tumors showed reduced expression of hMSH2, hMLH1, GTBP, hPMS2, and hPMS1 respectively. Multivariate analysis revealed a significant correlation between the expression level of hMSH2(P= 0.008), hMLH1 (P= 0.001) and GTBP (P = 0.032)and HCC, between hPMS2, GTBP and HCVassociated HCC (P<0.001, 0.002).CONCLUSION: Reduced expression of MMR genes seemsto play an important role in HCV-associated HCC. hPMS2 islikely involved at an early stage of hepatocarcinogenesis since it was detected in normal adjacent tissues. Reduced expression of hPMS2 provides a growth advantage and stimulates proliferation which encourages malignant transformation in non-cirrhotic HCV-infected patients via acquisition of more genetic damages.

  14. Oxidation of Refractory Benzothiazoles with PMS/CuFe2O4: Kinetics and Transformation Intermediates

    KAUST Repository

    Zhang, Tao

    2016-05-04

    Benzothiazole (BTH) and its derivatives, 2-(methylthio)bezothiazole (MTBT), 2-benzothiazolsulfonate (BTSA) and 2-hydroxybenzothiazole (OHBT), are refractory pollutants ubiquitously existing in urban runoff at relatively high concentrations. Here, we report their oxidation by CuFe2O4-activated peroxomonosulfate (PMS/CuFe2O4), focusing on kinetics and transformation intermediates. These benzothiazoles can be efficiently degraded by this oxidation process which is confirmed to generate mainly sulfate radicals (with negligible hydroxyl-radical formation) under slightly acidic to neutral pH conditions. The molar exposure ratio of sulfate radical to residual PMS (i.e. Rct) of this process is a constant which is related to reaction condition and can be easily determined. Reaction rate constants of these benzothiazoles towards sulfate radical are (3.3 ± 0.3) × 109, (1.4 ± 0.3) × 109, (1.5 ± 0.1) × 109 and (4.7 ± 0.5) × 109 M-1s-1, respectively (pH 7 and 20 oC). Based on Rct and these rate constants, their degradation in the presence of organic matter can be well predicted. A number of transformation products were detected and tentatively identified using triple-quadruple/linear ion trap MS/MS and high-resolution MS. It appears that sulfate radicals attack BTH, MTBT and BTSA on their benzo ring via electron transfer, generating multiple hydroxylated intermediates which are reactive towards common oxidants. For OHBT oxidation, it prefers to break down the thiazole ring. Due to competitions of the transformation intermediates, a minimum PMS/pollutant molar ratio of 10-20 is required for effective degradation. The flexible PMS/CuFe2O4 could be a useful process to remove the benzothiazoles from low DOC waters like urban runoff or polluted groundwater.

  15. Development of adaptive core emulator for PMS-XRBP of CE type plant

    Energy Technology Data Exchange (ETDEWEB)

    Song, Jae Seung; Zee, Sung Quun; Lee, Chung Chan; Lee, Ki Bog; Rhy, Hyo Sang; Chang, Jong Hwa; Lee, Young Ouk; Baek, Seung Min; Seo, Ho Joon

    1996-12-01

    The purpose of this report is to develop ONED-based adaptive core emulator (ACE) for Korean Standard Nuclear Power Plant. This report is first year report and includes (1) augmentation of ONED94 I/O system (2) non-equilibrium xenon initialization for core transient simulation (3) ONED94 verification via plant measurements (4) automatic data link system from PMS and personal computer. (author). 4 tabs., 4 figs., 8 refs.

  16. The PM/S module and the BIO/TSR requirements comparison report summary

    Energy Technology Data Exchange (ETDEWEB)

    PEERY, B.Q.

    1999-02-24

    This report summarizes the comparison between the Preventive Maintenance/Surveillance System (PM/S) database and the requirements identified in the Tank Waste Remediation Systems Basis for Interim Operation (BIO) (HNF-SD-WM-BIO-001); the Technical Safety Requirements (TSR's) (HNF-SD-WM-TSR-006); The Tank Farms Administrative Controls Manual, (HNF-IP-1266); and The TWRS Facility Safety Equipment List, (HNF-SD-WM-SEL-0404). Corrective actions identified are completed or in process.

  17. Over Saturation in SiPMs: The Difference Between Signal Charge and Signal Amplitude

    CERN Document Server

    Ahnen, Max Ludwig

    2015-01-01

    A recent report on the over saturation in SiPMs is puzzling. The measurements, using a variety of SiPMs, show an excess in signal far beyond the physical limit of the number of SiPM microcells without indication of an ultimate saturation. In this work I propose a solution to this problem. Different measurements and theoretical models of avalanche propagation indicate that multiple simultaneous primary avalanches produce an ever narrower and faster signal. This is because of a speed-up of effective avalanche propagation processes. It means that SiPMs, operated at their saturation regime, should become faster the more light they detect. Therefore, signal extraction methods that use the amplitude of the signal should see an over saturation effect. Measurements with a commercial SiPM illuminated with bright picosecond pulses in the saturation regime demonstrate that indeed the rising edge of the SiPM signal gets faster as the light pulses get brighter. A signal extractor based on the amplitude shows a nonlinear b...

  18. Analog filtering methods improve leading edge timing performance of multiplexed SiPMs

    Science.gov (United States)

    Bieniosek, M. F.; Cates, J. W.; Grant, A. M.; Levin, C. S.

    2016-08-01

    Multiplexing many SiPMs to a single readout channel is an attractive option to reduce the readout complexity of high performance time of flight (TOF) PET systems. However, the additional dark counts and shaping from each SiPM cause significant baseline fluctuations in the output waveform, degrading timing measurements using a leading edge threshold. This work proposes the use of a simple analog filtering network to reduce the baseline fluctuations in highly multiplexed SiPM readouts. With 16 SiPMs multiplexed, the FWHM coincident timing resolution for single 3~\\text{mm}× 3~\\text{mm}× 20 mm LYSO crystals was improved from 401  ±  4 ps without filtering to 248  ±  5 ps with filtering. With 4 SiPMs multiplexed, using an array of 3~\\text{mm}× 3~\\text{mm}× 20 mm LFS crystals the mean time resolution was improved from 436  ±  6 ps to 249  ±  2 ps. Position information was acquired with a novel binary positioning network. All experiments were performed at room temperature with no active temperature regulation. These results show a promising technique for the construction of high performance multiplexed TOF PET readout systems using analog leading edge timing pickoff.

  19. Large area UV SiPMs with extremely low cross-talk

    Science.gov (United States)

    Dolgoshein, B.; Mirzoyan, R.; Popova, E.; Buzhan, P.; Ilyin, A.; Kaplin, V.; Stifutkin, A.; Teshima, M.; Zhukov, A.

    2012-12-01

    For about ten years the collaboration MEPhI-Max Plank Institute for Physics in Munich has been developing SiPMs for the MAGIC and EUSO astro-particle physics experiments. The aim was to develop UV sensitive sensors of very high photon detection efficiency, substantially exceeding that of the classical photo multiplier tubes. For very high photo detection efficiency one needs to operate SiPM under the highest Geiger efficiency, i.e., to apply a high over-voltage. This means operating SiPM under high gain that in its turn produces a very high cross-talk. For suppressing the latter adverse effect we used isolating trenches and a second p-n junction, but also special implantation profiles and layers. We produced UV sensitive SiPMs of sizes 1 mm×1 mm and 3 mm×3 mm showing a peak Photon Detection Efficiency in the range of 50-60% at a cross-talk level of only 3-5%. One of the outstanding features of the new SiPM is their extremely low sensitivity of gain to temperature variations, amounting to 0.5%/°C. Below we report on new SiPMs.

  20. Study of detection efficiency distribution and areal homogeneity of SiPMs

    CERN Document Server

    Tesař, Michal; Ninković, Jelena; Simon, Frank

    2012-01-01

    The analog hadron calorimeter for the International Linear Collider (ILC) of the CALICE collaboration utilized novel silicon detectors, the Sillicon Photomultipliers (SiPMs), for the detection of scintillation light coming from very small scintillator cells 3x3x0.5 cm^3. This technology allows the construction of highly granular calorimeters used for excellent shower separation and therefore outstanding jet energy resolution using the particle flow concept. Since the SiPMs still have potential for further improvements, we developed a setup dedicated to the measurement of parameters like the areal distribution of relative photon detection efficiency and crosstalk probability which are used to characterize and compare different devices. Thanks to the precise positioning system together with excellent focusing of the light source we are capable of scanning whole SiPMs with an area of ca. 1 mm^2 at a sub-pixel resolution of 1-2 \\mu{}m. A further alignment compensation feature allows us to conduct separate analysi...

  1. pms3 is the locus causing the original photoperiod-sensitive male sterility mutation of‘Nongken 58S’

    Institute of Scientific and Technical Information of China (English)

    梅明华; 陈亮; 章志宏; 李子银; 徐才国; 张启发

    1999-01-01

    Photoperiod-sensitive genic male sterile (PSGMS) rice is a very useful germplasm for hybrid rice development. It was first found as a spontaneous mutant in a japonica cultivar ’Nongken 58’. pms3 on chromosome 12 was determined to be the locus where the original PSGMS mutation occurred, changing the normal cultivar Nongken 58 to PSGMS Nongken 58S. Large amounts of RAPD and AFLP analyses were also conducted for the fine mapping of the pms3 genomic region, which resulted in 4 molecular markers linked to pms3. Although these markers somewhat increased the marker density of this region, the pms3 locus is still located in a marker-sparse region.

  2. Effectiveness of group cognitive-behavioral therapy ‎on ‎symptoms of premenstrual syndrome (PMS

    Directory of Open Access Journals (Sweden)

    Maryam Maddineshat

    2016-02-01

    Full Text Available Objective: Standards of care and treatment of premenstrual syndrome (PMS vary. Non-drug ‎psychosocial intervention therapy is recommended for women with any kind of ‎discomfort or distress caused by PMS. The current study examined the effectiveness of ‎group cognitive-behavioral therapy on the symptoms of PMS at a girls’ dormitory of ‎North Khorasan University of Medical Sciences.Method: In this quasi-experimental study, 32 female students with PMS who were majoring in ‎nursing and midwifery and residing in the dormitory were selected using the ‎convenience sampling method and were assigned to experimental and control groups. ‎The Standardized Premenstrual Symptoms Screening Tool was used as the research ‎tool. Eight sessions of cognitive-behavioral group therapy were held for the studentsResults: There was a significant difference in psychological symptoms before and after ‎cognitive-behavioral therapy (p=0.012. Furthermore, cognitive-behavioral therapy was ‎effective on social interferences caused by PMS symptoms (p=0.012.‎Conclusion: Group cognitive-behavioral therapy effectively alleviates PMS symptoms in female ‎college students.‎

  3. Uniformity Studies of Scintillator Tiles directly coupled to SiPMs for Imaging Calorimetry

    CERN Document Server

    Simon, Frank

    2010-01-01

    We present a novel geometry of scintillator tiles developed for fiberless coupling to silicon photomultipliers (SiPMs) for applications in highly granular calorimeters. A high degree of uniformity of the tile response over the full active area was achieved by a drilled slit at the coupling position of the photon sensor with 2 mm, 4 mm and 5.5 mm in height, width and depth. Detailed measurements of the response to penetrating electrons were performed for tiles with a lateral size of 3 x 3 cm^2 and thicknesses of 5 mm and 3 mm.

  4. Study of the characteristics of SiPMs matrix as a photosensor for the scintillation detectors

    CERN Document Server

    Dzaparova, I M; Gavrilyuk, Yu M; Petkov, V B; Sergeev, A V; Volchenko, V I; Yakimenko, S P; Yanin, A F

    2015-01-01

    The matrices formed of silicon photomultipliers (SiPMs) are very promising photosensors for the scintillation detectors. The use of SiPM matrices with appropriate optical collector gives, in principle, a possibility to do a snapshot of glowing track of charged particle traversing a scintillator. The prototype of such scintillation detector is under development now in INR RAS. The preliminary results of characterization study of the matrix ArrayC-60035-64P-PCB (SensL company) for the prototype of such detector are presented.

  5. Detector block based on arrays of 144 SiPMs and monolithic scintillators: A performance study

    Energy Technology Data Exchange (ETDEWEB)

    González, A.J.; Conde, P.; Iborra, A. [Institute for Instrumentation in Molecular Imaging (I3M), Universidad Politécnica de Valencia – CSIC – CIEMAT (Spain); Aguilar, A. [Communications and Digital Systems Design Group (DSDC), Universidad de Valencia (Spain); Bellido, P. [Institute for Instrumentation in Molecular Imaging (I3M), Universidad Politécnica de Valencia – CSIC – CIEMAT (Spain); García-Olcina, R. [Communications and Digital Systems Design Group (DSDC), Universidad de Valencia (Spain); Hernández, L.; Moliner, L.; Rigla, J.P.; Rodríguez-Álvarez, M.J.; Sánchez, F.; Seimetz, M.; Soriano, A. [Institute for Instrumentation in Molecular Imaging (I3M), Universidad Politécnica de Valencia – CSIC – CIEMAT (Spain); Torres, J. [Communications and Digital Systems Design Group (DSDC), Universidad de Valencia (Spain); Vidal, L.F.; Benlloch, J.M. [Institute for Instrumentation in Molecular Imaging (I3M), Universidad Politécnica de Valencia – CSIC – CIEMAT (Spain)

    2015-07-01

    We have developed a detector block composed by a monolithic LYSO scintillator coupled to a custom made 12×12 SiPMs array. The design is mainly focused to applications such as Positron Emission Tomography. The readout electronics is based on 3 identical and scalable Application Specific Integrated Circuits (ASIC). We have determined the main performance of the detector block namely spatial, energy, and time resolution but also the system capability to determine the photon depth of interaction, for different crystal surface treatments. Intrinsic detector spatial resolution values as good as 1.7 mm FWHM and energies of 15% for black painted crystals were measured.

  6. Comparing the Effects of Vitamin B1 and Calcium on Premenstrual Syndrome (PMS among Female Students, Ilam- Iran

    Directory of Open Access Journals (Sweden)

    Soheila Samieipour

    2016-09-01

    Full Text Available Background Premenstrual syndrome (PMS is a combination of physical, psychological and emotional symptoms that occur periodically before menstruation and disappear with the onset of menstruation. There are some therapeutic methods mostly according to the clinical trials that reduce the prevalence and intensity of symptoms of PMS by unknown mechanisms. This study aimed to investigate the effects of Calcium and vitamin B1 on Premenstrual syndrome among female students. Materials and Methods: This is a triple-blind clinical trial conducted on 210 female students living in dormitories of Ilam University of Medical Sciences who had PMS. PMS symptoms questionnaire was used to investigate the symptoms. Participants were assigned in 3 groups of 70 people with the following regimen: group 1 received one pill containing 100 milligrams vitamin B1, group 2 received Calcium pills and group 3 received placebo. The participants in all groups took medicines for 2 months and then reported the intensity of their symptoms by the questionnaire. The collected data was analyzed by descriptive and inferential statistics, using SPSS-16. Results: In groups receiving vitamin B1, Calcium and placebo, the intensity of physical and psychological symptoms as well as general symptoms of PMS had a remarkable reduction (P

  7. Magnetic and Gravitational Disk-Star Interactions: An Interdependence of PMS Stellar Rotation Rates and Spin-Orbit Misalignments

    CERN Document Server

    Batygin, Konstantin

    2013-01-01

    The presence of giant gaseous planets that reside in close proximity to their host stars may be a consequence of large-scale radial migration through the proto-planetary nebulae. Within the context of this picture, significant orbital obliquities characteristic of a substantial fraction of such planets can be attributed to external torques that perturb the disks out of alignment with the spin axes of their host stars. Therefore, the acquisition of orbital obliquity exhibits sensitive dependence on the physics of disk-star interactions. Here, we analyze the primordial excitation of spin-orbit misalignment of Sun-like stars, in light of disk-star angular momentum transfer. We begin by calculating the stellar pre-main sequence rotational evolution, accounting for spin-up due to gravitational contraction and accretion as well as spin-down due to magnetic star-disk coupling. We devote particular attention to angular momentum transfer by accretion, and show that while generally subdominant to gravitational contract...

  8. FORMULASI MINUMAN SUPLEMEN DAUN TORBANGUN (Coleus amboinicus Lour. UNTUK WANITA YANG MENDERITA PMS (PREMENSTRUAL SYNDROME

    Directory of Open Access Journals (Sweden)

    Pramadya Alfitra

    2012-03-01

    Full Text Available 800x600 Normal 0 false false false IN X-NONE X-NONE MicrosoftInternetExplorer4 Torbangun (Coleus amboinicus Lour is one of Labiatae family containing a lot of micronutrients and active components. The plant is used as traditional medicine for relieving premenstrual syndromes (PMS. Based on the results of previous studies, a capsule containing 750 mg of dried Torbangun leaves can relieve PMS as well as commercial herbal, and better than placebo. Capsule supplement form seems less acceptable because it tastes like taking a drug. Therefore, it requires development for Torbangun supplement product in other forms, and one of them is a supplement drink. The study is aimed to formulate  a supplement drink from Torbangun leaves as the basic ingredients. Supplement drink formulation is made in trial and error by combining extract of torbangun leaves, sucrose, and lemon, obtaining three formulas: DT1 contains 10 g extract of torbangun leaves and 16 g sucrose, DT2 contains 10 g extract of torbangun leaves, 2 g lemon, 22 g sucrose, and DT3 contains 10 g extract of torbangun leaves, 4 g lemon, and 28 g sucrose. These formulas are then tested by organoleptic, physical, and chemical. The results show that the formula DT3 has the highest average score. Blanching treatment improves organoleptic properties of supplement drinks. Mean scores in color, aroma, and taste of the blanched supplement drink are different (p Key words: Torbangun leaves, premenstrual syndrome, supplement drink, blanching.

  9. Methods for Developing Patient-Reported Outcome-Based Performance Measures (PRO-PMs).

    Science.gov (United States)

    Basch, Ethan; Spertus, John; Dudley, R Adams; Wu, Albert; Chuahan, Cynthia; Cohen, Perry; Smith, Mary Lou; Black, Nick; Crawford, Amaris; Christensen, Keri; Blake, Kathleen; Goertz, Christine

    2015-06-01

    To recommend methods for assessing quality of care via patient-reported outcome-based performance measures (PRO-PMs) of symptoms, functional status, and quality of life. A Technical Expert Panel was assembled by the American Medical Association-convened Physician Consortium for Performance Improvement. An environmental scan and structured literature review were conducted to identify quality programs that integrate PRO-PMs. Key methodological considerations in the design, implementation, and analysis of these PRO-PM data were systematically identified. Recommended methods for addressing each identified consideration were developed on the basis of published patient-reported outcome (PRO) standards and refined through public comment. Literature review focused on programs using PROs to assess performance and on PRO guidance documents. Thirteen PRO programs and 10 guidance documents were identified. Nine best practices were developed, including the following: provide a rationale for measuring the outcome and for using a PRO-PM; describe the context of use; select a measure that is meaningful to patients with adequate psychometric properties; provide evidence of the measure's sensitivity to differences in care; address missing data and risk adjustment; and provide a framework for implementation, interpretation, dissemination, and continuous refinement. Methods for integrating PROs into performance measurement are available. Copyright © 2015 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  10. 3D position determination in monolithic crystals coupled to SiPMs for PET.

    Science.gov (United States)

    Etxebeste, Ane; Barrio, John; Muñoz, Enrique; Oliver, Josep F; Solaz, Carles; Llosá, Gabriela

    2016-05-21

    The interest in using continuous monolithic crystals in positron emission tomography (PET) has grown in the last years. Coupled to silicon photomultipliers (SiPMs), the detector can combine high sensitivity and high resolution, the two main factors to be maximized in a positron emission tomograph. In this work, the position determination capability of a detector comprised of a [Formula: see text] mm(3) LYSO crystal coupled to an [Formula: see text]-pixel array of SiPMs is evaluated. The 3D interaction position of γ-rays is estimated using an analytical model of the light distribution including reflections on the facets of the crystal. Monte Carlo simulations have been performed to evaluate different crystal reflectors and geometries. The method has been characterized and applied to different cases. Intrinsic resolution obtained with the position estimation method used in this work, applied to experimental data, achieves sub-millimetre resolution values. Average resolution over the detector surface for 5 mm thick crystal is  ∼0.9 mm FWHM and  ∼1.2 mm FWHM for 10 mm thick crystal. Depth of interaction resolution is close to 2 mm FWHM in both cases, while the FWTM is  ∼5.3 mm for 5 mm thick crystal and  ∼9.6 mm for 10 mm thick crystal.

  11. Vicarious absolute radiometric calibration of GF-2 PMS2 sensor using permanent artificial targets in China

    Science.gov (United States)

    Liu, Yaokai; Li, Chuanrong; Ma, Lingling; Wang, Ning; Qian, Yonggang; Tang, Lingli

    2016-10-01

    GF-2, launched on August 19 2014, is one of the high-resolution land resource observing satellite of the China GF series satellites plan. The radiometric performance evaluation of the onboard optical pan and multispectral (PMS2) sensor of GF-2 satellite is very important for the further application of the data. And, the vicarious absolute radiometric calibration approach is one of the most useful way to monitor the radiometric performance of the onboard optical sensors. In this study, the traditional reflectance-based method is used to vicarious radiometrically calibrate the onboard PMS2 sensor of GF-2 satellite using three black, gray and white reflected permanent artificial targets located in the AOE Baotou site in China. Vicarious field calibration campaign were carried out in the AOE-Baotou calibration site on 22 April 2016. And, the absolute radiometric calibration coefficients were determined with in situ measured atmospheric parameters and surface reflectance of the permanent artificial calibration targets. The predicted TOA radiance of a selected desert area with our determined calibrated coefficients were compared with the official distributed calibration coefficients. Comparison results show a good consistent and the mean relative difference of the multispectral channels is less than 5%. Uncertainty analysis was also carried out and a total uncertainty with 3.87% is determined of the TOA radiance.

  12. 新型四氢呋喃衍生物PMS777促智作用的量效关系%Dose-response Relationship of a Novel Tetrahydrofuran Derivative PMS777 for Cognitive Enhancement

    Institute of Scientific and Technical Information of China (English)

    高小玲; 李娟; 黄泓; Jean-Marc Miezan Ezoulin; France Massicot; Chang-Zhi Dong; Fran(c)oise Heymans; 陈红专

    2005-01-01

    目的研究新型四氢呋喃衍生物PMS777对东莨菪碱所致的小鼠记忆障碍模型的改善作用及其量效关系.方法成年雄性小鼠利用Morris水迷宫装置训练4天后,用东莨菪碱(2 mg/kg,i.p)造成小鼠记忆障碍模型,观察不同剂量的PMS777(i.p)对小鼠上台潜伏期和上台前游泳距离的影响.结果 PMS777(0.5-2.5 mg/kg)预处理组小鼠的上台潜伏期及游泳距离明显缩短(与模型组比较,P<0.05或P<0.01).PMS777(0.25-5 mg/kg)对记忆的作用呈现明显的倒"U型"效应;在0.25-1 mg/kg的剂量范围内,PMS777的促智作用随剂量增高而增加.结论 PMS777在一定剂量范围内能显著地改善东莨菪碱所致的小鼠记忆障碍,提示有望成为潜在治疗阿尔茨海默病的先导化合物.

  13. CLARO-CMOS, an ASIC for single photon counting with Ma-PMTs, MCPs and SiPMs

    Science.gov (United States)

    Carniti, P.; Cibinetto, G.; Cotta Ramusino, A.; Giachero, A.; Gotti, C.; Maino, M.; Malaguti, R.; Pessina, G.

    2013-01-01

    An ASIC named CLARO-CMOS was designed for fast photon counting with MaPMTs, MCPs and SiPMs. The prototype was realized in a .35 μm CMOS technology and has four channels, each with a fast amplifier and a discriminator. The main features of the design are the high speed of operation and the low power dissipation, below 1 mW per channel. This paper focuses on the use of the CLARO for SiPM readout. The ASIC was tested with several SiPMs of various sizes, connected to the input of the chip both directly and through a coaxial cable about one meter long. In the latter case the ASIC is still fully functional although the speed of response is affected by the cable capacitance. The threshold could be set just above the single photoelectron level, and with 1 ×1 mm2 SiPMs the discrete photoelectron peaks could be well resolved.

  14. Studies on surface-mounted SiPMs in 2015 testbeam of a highly granular hadron calorimeter

    Energy Technology Data Exchange (ETDEWEB)

    Krause, Sascha [Institut fuer Physik, Johannes Gutenberg-Universitaet Mainz, Mainz (Germany); Collaboration: CALICE-D-Collaboration

    2016-07-01

    To achieve excellent jet energy resolution, a highly granular hadronic calorimeter is being developed within the CALICE collaboration. Therefore, about 8 million detector units consisting of scintillator tiles and silicon photomultipliers (SiPMs) will be installed in the final HCAL design. The usage of surface-mounted (SMD) SiPMs allows an automated mass assembly. During CERN SPS testbeam 2015, data for a prototype consisting of up to 11 layers of HCAL base units (HBU) was collected using electron, muon and pion beams. One of the layers was equipped with the first SMD HBU. Results and performance, especially of the SMD HBU are presented.

  15. Innovative PET detector concept based on SiPMs and continuous crystals

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez Martinez, A.J., E-mail: agonzalez@i3m.upv.es [Instituto de Instrumentacion para Imagen Molecular (I3M), Centro Mixto UPV - CSIC - CIEMAT, Camino de Vera s/n, 46022 Valencia (Spain); ONCOVISION (GEM-Imaging S.A.), 46012 Valencia (Spain); Peiro Cloquell, A.; Sanchez Martinez, F.; Vidal San Sebastian, L.F.; Benlloch Baviera, J.M. [Instituto de Instrumentacion para Imagen Molecular (I3M), Centro Mixto UPV - CSIC - CIEMAT, Camino de Vera s/n, 46022 Valencia (Spain)

    2012-12-11

    The use of Silicon Photomultipliers (SiPM) has been proposed for Positron Emission Tomography (PET) readout because they are hardly affected by magnetic fields and their time response enables Time of Flight measurements. This work proposes an array of SiPM to be coupled to a monolithic LYSO crystal by means of a series of optical devices. The emitted light distribution by the scintillation crystal will be accurately determined using an Application Specific Integrated Circuit. The described sensor block aims to determine the planar coordinates and depth of interaction of the gamma ray with sub-millimetrical precision. In this work we present the initial studies regarding edge effects due to thick monolithic crystals and how to overcome these limitations by means of optical devices namely faceplates and light concentrators. We will also discuss on the alignment of such optical devices with the SiPMs.

  16. Low-cost RFID-based palm oil monitoring system (PMS): First prototype

    Science.gov (United States)

    Kiama, J. W.; Raman, V.; Patrick, T. H. H.

    2014-02-01

    Under collaboration with our local oil palm plantation enterprise, our research focuses on producing proof-of-concept by using RFID technology to monitor palm oil productivity. Passive RFID tags are used in the plantation field to uniquely identify each palm oil tree and their Fresh Fruit Bunches (FFB) production is collected and monitored by scanning the passive RFID tags using high frequency RFID scanners. This technology aims to convert the harvest data into digital information which can be processed and analyzed by PMS system and presented as informative outputs such as dynamic charts. This analyzed information is further used as input to a proprietary GIS system where it is mapped as color-coded spatial data which enables an accurate evaluation and monitoring of the overall plantation productivity.

  17. Time resolution of time-of-flight detector based on multiple scintillation counters readout by SiPMs

    CERN Document Server

    Cattaneo, P W; Gatti, F; Nishimura, M; Ootani, W; Rossella, M; Shirabe, S; Uchiyama, Y

    2015-01-01

    A new timing detector measuring ~50 MeV/c positrons is under development for the MEG II experiment, aiming at a time resolution $\\sigma_t \\sim 30~\\mathrm{ps}$. The resolution is expected to be achieved by measuring each positron time with multiple counters made of plastic scintillator readout by silicon photomultipliers (SiPMs). The purpose of this work is to demonstrate the time resolution for ~50 MeV/c positrons using prototype counters. Counters with dimensions of $90\\times 40\\times 5~\\mathrm{mm}^3$ readout by three SiPMs at each end were build with SiPMs from Hamamatsu Photonics and AdvanSiD and tested in a positron beam at the DA$\\Phi$NE Beam Test Facility. It was found that the time resolution improves nearly as the square root of the number of counter hits. A time resolution $\\sigma_t=26.2\\pm1.3~\\mathrm{ps}$ was obtained with eight counters with Hamamatsu SiPMs. These results suggest that the design resolution is achievable in the MEG II experiment.

  18. Levels of H-ras codon 61 CAA to AAA mutation: response to 4-ABP-treatment and Pms2-deficiency.

    Science.gov (United States)

    Parsons, Barbara L; Delongchamp, Robert R; Beland, Frederick A; Heflich, Robert H

    2006-01-01

    DNA mismatch repair (MMR) deficiencies result in increased frequencies of spontaneous mutation and tumor formation. In the present study, we tested the hypothesis that a chemically-induced mutational response would be greater in a mouse with an MMR-deficiency than in the MMR-proficient mouse models commonly used to assay for chemical carcinogenicity. To accomplish this, the induction of H-ras codon 61 CAA-->AAA mutation was examined in Pms2 knockout mice (Pms2-/-, C57BL/6 background) and sibling wild-type mice (Pms2+/+). Groups of five or six neonatal male mice were treated with 0.3 micromol 4-aminobiphenyl (4-ABP) or the vehicle control, dimethylsulfoxide. Eight months after treatment, liver DNAs were isolated and analysed for levels of H-ras codon 61 CAA-->AAA mutation using allele-specific competitive blocker-PCR. In Pms2-proficient and Pms2-deficient mice, 4-ABP treatment caused an increase in mutant fraction (MF) from 1.65x10(-5) to 2.91x10(-5) and from 3.40x10(-5) to 4.70x10(-5), respectively. Pooling data from 4-ABP-treated and control mice, the approximately 2-fold increase in MF observed in Pms2-deficient as compared with Pms2-proficient mice was statistically significant (P=0.0207) and consistent with what has been reported previously in terms of induction of G:C-->T:A mutation in a Pms2-deficient background. Pooling data from both genotypes, the increase in H-ras MF in 4-ABP-treated mice, as compared with control mice, did not reach the 95% confidence level of statistical significance (P=0.0606). The 4-ABP treatment caused a 1.76-fold and 1.38-fold increase in average H-ras MF in Pms2-proficient and Pms2-deficient mice, respectively. Furthermore, the levels of induced mutation in Pms2-proficient and Pms2-deficient mice were nearly identical (1.26x10(-5) and 1.30x10(-5), respectively). We conclude that Pms2-deficiency does not result in an amplification of the H-ras codon 61 CAA-->AAA mutational response induced by 4-ABP.

  19. ACIS-I observations of NGC2264. Membership and X-ray properties of PMS stars

    CERN Document Server

    Flaccomio, E; Sciortino, S

    2006-01-01

    We analyze a deep, 100 ksec long, Chandra ACIS observation of NGC2264. We detect 420 sources, 85% of which are associated with known optical and NIR counterparts. More than 90% of these counterparts are NGC2264 members, thus significantly increasing the known low mass cluster population by about 100 objects. Among the sources without counterpart, ~50% are likely members, several of which we expect to be previously unknown protostellar objects. We confirm several previous findings on the X-ray activity of low mass PMS stars: X-ray luminosity is related to stellar mass, although with a large scatter; L_X/L_bol is close to but almost invariably below the saturation level, 1e-3. A comparison between CTTS and WTTS shows several differences: CTTS are on average less active than WTTS; their emission may also be more time variable and is on average slightly harder. However, we find evidence in some CTTS of extremely cool, ~0.1-0.2 keV, plasma which we speculate is heated by accretion shocks. We conclude that activity...

  20. Scintillating fiber detectors for precise time and position measurements read out with Si-PMs

    Science.gov (United States)

    Damyanova, A.; Bravar, A.

    2017-02-01

    We present the development and performance of compact scintillating fiber detectors read out with silicon photo-multipliers (Si-PMs). The compact size, fast response, and insensitivity to magnetic fields make these detectors suitable for a variety of applications where precise tracking and timing information is required. These detectors will be used with different particle beams (electrons, protons, heavy ions) at very high rates. In particular, we present the SciFi tracker/time of flight detector that is being developed for the Mu3e experiment at PSI (search for the lepton flavor violating decay μ → eee at very high rates). We also present the SciFi beam position detectors that will be employed in NA61 at CERN to track the incoming proton and heavy ion beam particles. We are considering different readout scenarios in which (a) each fiber is individually coupled to a single Si-PM photo-sensor and (b) fibers are arranged in columns and coupled to a Si-PM arrays.

  1. Results of a combined monolithic crystal and an array of ASICs controlled SiPMs

    Energy Technology Data Exchange (ETDEWEB)

    Conde, P.; González, A.J., E-mail: agonzalez@i3m.upv.es; Hernández, L.; Bellido, P.; Iborra, A.; Crespo, E.; Moliner, L.; Rigla, J.P.; Rodríguez-Álvarez, M.J.; Sánchez, F.; Seimetz, M.; Soriano, A.; Vidal, L.F.; Benlloch, J.M.

    2014-01-11

    In this work we present the energy and spatial resolutions we have obtained for a γ-ray detector based on a monolithic LYSO crystal coupled to an array of 256 SiPMs. Two crystal configurations of the same trapezoidal shape have been tried. In one approach all surfaces were black painted but the exit one facing the photosensor array which was polished. The other approach included a retroreflector (RR) layer coupled to the entrance face of the crystal powering the amount of transmitted light to the photosensors. Two coupling media between the scintillator and the SiPM array were used, namely direct coupling by means of optical grease and coupling through an array of light guides. Since the same operational voltage was supplied to the entire array, it was needed to equalize their gains before feeding their signals to the Data Acquisition system. Such a job was performed by means of 4 scalable Application Specific Circuits (ASICs). An energy resolution of about 24.4% has been achieved for the direct coupling with the RR layer together with a spatial resolution of approximately 2.9 mm at the detector center. With the light guides coupling the effects of image compression at the edges are significantly minimized, but worsening the energy resolution to about 33.1% with a spatial resolution nearing 4 mm at the detector center.

  2. Effects of CeO2 doping on the structure and properties of PSN-PZN-PMS-PZT piezoelectric ceramics

    Institute of Scientific and Technical Information of China (English)

    SUN Qingchi; LU Cuimin; ZHOU Hua

    2005-01-01

    Quinary system piezoelectric ceramics PSN-PZN-PMS-PZT were prepared by using a two-step method. The effects of CeO2 doping on piezoelectric and dielectric properties of the system were investigated at morphotropic phase boundary (MPB). The results reveal that the relative dielectric constant εT33 / ε0, the Curie temperature Tc, the piezoelectric constant d33, the mechanical quality factor Qm, and the electromechanical coupling coefficient Kp are changed with the increase of CeO2 content. On the other hand, the effects of CeO2 doping on the dielectric properties of PSN-PZN-PMS-PZT piezoelectric ceramics at high electric field are consistent with the change at weak electric field. The values of dielectric constant and dielectric loss are enhanced with the increasing of electric field.

  3. Supersaturation and Activity-Rotation Relation in PMS stars: the case of the Young Cluster h Per

    CERN Document Server

    Argiroffi, C; Micela, G; Sciortino, S; Moraux, E; Bouvier, J; Flaccomio, E

    2016-01-01

    The magnetic activity of late-type MS stars is characterized by different regimes, and their activity levels are well described by Ro, the ratio between P_rot and the convective turnover time. Very young PMS stars show, similarly to MS stars, intense magnetic activity. However they do not show clear activity-rotation trends, and it still debated which stellar parameters determine their magnetic activity levels. To bridge the gap between MS and PMS stars, we studied the activity-rotation relation in the young cluster h Per, a ~13 Myr old cluster, that contains both fast and slow rotators, whose members have ended their accretion phase and have already developed a radiative core. It offers us the opportunity to study the activity level of intermediate-age PMS stars with different rotational velocities, excluding any interactions with the circumstellar environment. We constrained the magnetic activity levels of h Per members measuring their X-ray emission from a Chandra observation, while P_rot were obtained by ...

  4. Study of Viability and Challenges of using SiPMs as an Alternative to PMT’s in Scintillation Detectors for Nuclear Safeguards

    Energy Technology Data Exchange (ETDEWEB)

    Iliev, Metodi [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-05-22

    The goals of this project are to identify fundamental and practical problems and features with SiPMs as they relate to IAEA detector needs, Identify published results and implementations of scintillation detectors tat use SiPMs that are of interest to IAEA, asses how effectively the fundamental problems were addresses, and perform simulations and experiments as needed to reproduce crucial results and make recommendations.

  5. A PET detector prototype based on digital SiPMs and GAGG scintillators.

    Science.gov (United States)

    Schneider, Florian R; Shimazoe, Kenji; Somlai-Schweiger, Ian; Ziegler, Sibylle I

    2015-02-21

    Silicon Photomultipliers (SiPM) are interesting light sensors for Positron Emission Tomography (PET). The detector signal of analog SiPMs is the total charge of all fired cells. Energy and time information have to be determined with dedicated readout electronics. Philips Digital Photon Counting has developed a SiPM with added electronics on cell level delivering a digital value of the time stamp and number of fired cells. These so called Digital Photon Counters (DPC) are fully digital devices. In this study, the feasibility of using DPCs in combination with LYSO (Lutetium Yttrium Oxyorthosilicate) and GAGG (Gadolinium Aluminum Gallium Garnet) scintillators for PET is tested. Each DPC module has 64 channels with 3.2 × 3.8775 mm(2), comprising 3200 cells each. GAGG is a recently developed scintillator (Zeff = 54, 6.63 g cm(-3), 520 nm peak emission, 46 000 photons MeV(-1), 88 ns (92%) and 230 ns (8%) decay times, non-hygroscopic, chemically and mechanically stable). Individual crystals of 2 × 2 × 6 mm(3) were coupled onto each DPC pixel. LYSO coupled to the DPC results in a coincidence time resolution (CTR) of 171 ps FWHM and an energy resolution of 12.6% FWHM at 511 keV. Using GAGG, coincidence timing is 310 ps FWHM and energy resolution is 8.5% FWHM. A PET detector prototype with 2 DPCs equipped with a GAGG array matching the pixel size (3.2 × 3.8775 × 8 mm(3)) was assembled. To emulate a ring of 10 modules, objects are rotated in the field of view. CTR of the PET is 619 ps and energy resolution is 9.2% FWHM. The iterative MLEM reconstruction is based on system matrices calculated with an analytical detector response function model. A phantom with rods of different diameters filled with (18)F was used for tomographic tests.

  6. A PET detector prototype based on digital SiPMs and GAGG scintillators

    Science.gov (United States)

    Schneider, Florian R.; Shimazoe, Kenji; Somlai-Schweiger, Ian; Ziegler, Sibylle I.

    2015-02-01

    Silicon Photomultipliers (SiPM) are interesting light sensors for Positron Emission Tomography (PET). The detector signal of analog SiPMs is the total charge of all fired cells. Energy and time information have to be determined with dedicated readout electronics. Philips Digital Photon Counting has developed a SiPM with added electronics on cell level delivering a digital value of the time stamp and number of fired cells. These so called Digital Photon Counters (DPC) are fully digital devices. In this study, the feasibility of using DPCs in combination with LYSO (Lutetium Yttrium Oxyorthosilicate) and GAGG (Gadolinium Aluminum Gallium Garnet) scintillators for PET is tested. Each DPC module has 64 channels with 3.2 × 3.8775 mm2, comprising 3200 cells each. GAGG is a recently developed scintillator (Zeff = 54, 6.63 g cm-3, 520 nm peak emission, 46 000 photons MeV-1, 88 ns (92%) and 230 ns (8%) decay times, non-hygroscopic, chemically and mechanically stable). Individual crystals of 2 × 2 × 6 mm3 were coupled onto each DPC pixel. LYSO coupled to the DPC results in a coincidence time resolution (CTR) of 171 ps FWHM and an energy resolution of 12.6% FWHM at 511 keV. Using GAGG, coincidence timing is 310 ps FWHM and energy resolution is 8.5% FWHM. A PET detector prototype with 2 DPCs equipped with a GAGG array matching the pixel size (3.2 × 3.8775 × 8 mm3) was assembled. To emulate a ring of 10 modules, objects are rotated in the field of view. CTR of the PET is 619 ps and energy resolution is 9.2% FWHM. The iterative MLEM reconstruction is based on system matrices calculated with an analytical detector response function model. A phantom with rods of different diameters filled with 18F was used for tomographic tests.

  7. Heavy incense burning in temples promotes exposure risk from airborne PMs and carcinogenic PAHs.

    Science.gov (United States)

    Chiang, Kuo-Chih; Liao, Chung-Min

    2006-12-15

    We present the mechanistic-based exposure and risk models, appraised with reported empirical data, to assess how the human exposure to airborne particulate matters (PMs) and carcinogenic polycyclic aromatic hydrocarbons (PAHs) during heavy incense burning episodes in temples. The models integrate size-dependent PM levels inside a temple from a published exploratory study associated with a human expiratory tract (HRT) model taking into account the personal exposure levels and size distributions in the HRT. The probabilistic exposure profiles of total-PAH levels inside a temple and internal PAHs doses are characterized by a physiologically based pharmacokinetic (PBPK) model with the reconstructed dose-response relationships based on an empirical three-parameter Hill equation model, describing PAHs toxicity for DNA adducts formation and lung tumor incidence responses in human white blood cells and lung. Results show that the alveolar-interstitial (AI) region has a lower mass median diameter (0.29 microm) than that in extrathoracic (ET(1), 0.37 microm), brochial (BB, 0.36 microm) and bronchiolar (bb, 0.32 microm) regions. The 50% probability (risk=0.5) of exceeding the DNA adducts frequency (DA(f)) ratio of 1.28 (95% CI: 0.55-2.40) and 1.78 (95% CI: 0.84-2.95) for external exposure of B[a]P and B[a]P(eq), respectively. The 10% (risk=0.1) probability or more of human affected by lung tumor is approximately 7.62x10(-5)% (95% CI: 3.39x10(-5)-1.71x10(-4)%) and 3.87x10(-4)% (95% CI: 1.72x10(-4)-8.69x10(-4)%) for internal exposure of B[a]P and B[a]P(eq), respectively. Our results implicate that exposure to smoke emitted from heavy incense burning may promote lung cancer risk. Our study provides a quantitative basis for objective risk prediction of heavy incense burning exposure in temples and for evaluating the effectiveness of management.

  8. Assessing pathogenicity of MLH1 variants by co-expression of human MLH1 and PMS2 genes in yeast

    Directory of Open Access Journals (Sweden)

    Hudler Petra

    2009-10-01

    Full Text Available Abstract Background Loss of DNA mismatch repair (MMR in humans, mainly due to mutations in the hMLH1 gene, is linked to hereditary nonpolyposis colorectal cancer (HNPCC. Because not all MLH1 alterations result in loss of MMR function, accurate characterization of variants and their classification in terms of their effect on MMR function is essential for reliable genetic testing and effective treatment. To date, in vivo assays for functional characterization of MLH1 mutations performed in various model systems have used episomal expression of the modified MMR genes. We describe here a novel approach to determine accurately the functional significance of hMLH1 mutations in vivo, based on co-expression of human MLH1 and PMS2 in yeast cells. Methods Yeast MLH1 and PMS1 genes, whose protein products form the MutLα complex, were replaced by human orthologs directly on yeast chromosomes by homologous recombination, and the resulting MMR activity was tested. Results The yeast strain co-expressing hMLH1 and hPMS2 exhibited the same mutation rate as the wild-type. Eight cancer-related MLH1 variants were introduced, using the same approach, into the prepared yeast model, and their effect on MMR function was determined. Five variants (A92P, S93G, I219V, K618R and K618T were classified as non-pathogenic, whereas variants T117M, Y646C and R659Q were characterized as pathogenic. Conclusion Results of our in vivo yeast-based approach correlate well with clinical data in five out of seven hMLH1 variants and the described model was thus shown to be useful for functional characterization of MLH1 variants in cancer patients found throughout the entire coding region of the gene.

  9. Simulation and characterization of different setups for gamma ray detection using SiPMs and LYSO scintillators

    Energy Technology Data Exchange (ETDEWEB)

    Benetti, M., E-mail: mbenetti@fbk.eu [INFN, Sezione di Padova (Gruppo Collegato di Trento) and Dipartimento di Ingegneria e Scienza dell' Informazione, Universita di Trento, Via Sommarive, 14, I-38123 Povo di Trento (Italy); Tarolli, A.; Giacomini, G.; Piemonte, C. [Fondazione Bruno Kessler, Centro per i Materiali e i Microsistemi (FBK-CMM), Via Sommarive, 18, I-38123 Povo di Trento (Italy); Dalla Betta, G.-F. [INFN, Sezione di Padova (Gruppo Collegato di Trento) and Dipartimento di Ingegneria e Scienza dell' Informazione, Universita di Trento, Via Sommarive, 14, I-38123 Povo di Trento (Italy)

    2011-12-01

    Silicon photomultipliers (SiPMs) coupled to fast bright scintillators, like cerium doped silicate based crystals, allow the construction of compact gamma ray detectors. In this paper we discuss simulation results obtained from Monte Carlo ray tracing tools applied to SiPM and LYSO systems. We address the importance of three key factors in light propagation: the scintillator wrapping, the coupling medium, and the detector coating. We also propose a simple experiment to verify some of the findings related to the investigation of diffusive wrappings.

  10. Development of event reconstruction algorithm for full-body gamma-camera based on SiPMs

    Science.gov (United States)

    Philippov, D. E.; Belyaev, V. N.; Buzhan, P. Zh; Ilyin, A. L.; Popova, E. V.; Stifutkin, A. A.

    2016-02-01

    The gamma-camera is the detector for nuclear medical imaging where the photomultiplier tubes (PMTs) could be replaced by the silicon photomultipliers (SiPMs). Common systems have the energy resolution about 10% and intrinsic spatial resolution about 3 mm (FWHM). In order to achieve the requirement energy and spatial resolution the classical Anger's logic should be modified. In case of a standard monolithic thallium activated sodium iodide scintillator (500x400x10 mm3) and SiPM readout it could be done with identification of the clusters. We show that this approach has a good results with the simulated data.

  11. A Quest for PMS candidate stars at low metallicity: Variable HAe/Be and Be stars in the Small Magellanic Cloud

    CERN Document Server

    De Wit, W J; Lamers, Henny J G L M; Lesquoy, E; Marquette, J B

    2003-01-01

    We report the discovery of 5 new Herbig Ae/Be candidate stars in the Small Magellanic Cloud in addition to the 2 reported in Beaulieu et al. (2001). We discuss these 7 HAeBe candidate stars in terms of (1) their irregular photometric variability, (2) their near infrared emission, (3) their Halpha emission and (4) their spectral type. One star has the typical photometric behaviour that is observed only among Pre-Main Sequence UX Orionis type stars. The objects are more luminous than Galactic HAeBe stars and Large Magellanic Cloud HAeBe candidates of the same spectral type. The stars were discovered in a systematic search for variable stars in a subset of the EROS2 database consisting of 115,612 stars in a field of 24x24 arcmin in the Small Magellanic Cloud. In total we discovered 504 variable stars. After classifying the different objects according to their type of variability, we concentrate on 7 blue objects with irregular photometric behaviour. We cross-identified these objects with emission line catalogues...

  12. Performance of VATA64HDR16 ASIC for medical physics applications based on continuous crystals and SiPMs

    Science.gov (United States)

    Barrio, J.; Etxebeste, A.; Lacasta, C.; Muñoz, E.; Oliver, J. F.; Solaz, C.; Llosá, G.

    2015-12-01

    Detectors based on Silicon Photomultipliers (SiPMs) coupled to continuous crystals are being tested in medical physics applications due to their potential high resolution and sensitivity. To cope with the high granularity required for a very good spatial resolution, SiPM matrices with a large amount of elements are needed. To be able to read the information coming from each individual channel, dedicated ASICs are employed. The VATA64HDR16 ASIC is a 64-channel, charge-sensitive amplifier that converts the collected charge into a proportional current or voltage signal. A complete assessment of the suitability of that ASIC for medical physics applications based on continuous crystals and SiPMs has been carried out. The input charge range is linear from 0-2 pC up to 55 pC. The energy resolution obtained at 511 keV is 10% FWHM with a LaBr3 crystal and 16% FWHM with a LYSO crystal. A coincidence timing resolution of 24 ns FWHM is obtained with two LYSO crystals.

  13. A design of scintillator tiles read out by surface-mounted SiPMs for a future hadron calorimeter

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Yong; Bauss, Bruno; Buescher, Volker; Caudron, Julien; Chau, Phi; Degele, Reinhold; Geib, Karl-Heinrich; Masetti, Lucia; Schaefer, Ulrich; Tapprogge, Stefan; Wanke, Rainer [Institut fuer Physik and PRISMA Detector Lab, Johannes Gutenberg-Universitaet Mainz (Germany)

    2015-07-01

    Precision calorimetry using highly granular sampling calorimeters is being developed based on the particle flow concept within the CALICE collaboration. One design option of a hadron calorimeter is based on silicon photomultipliers (SiPMs) to detect photons generated in plastic scintillator tiles. Driven by the need of automated mass assembly of around ten millions of channels stringently required by the high granularity, we developed a design of scintillator tiles directly coupled with surface-mounted SiPMs. A cavity is created in the center of the bottom surface of each tile to provide enough room for the whole SiPM package and to improve collection of the light produced by incident particles penetrating the tile at different positions. The cavity design has been optimized using a GEANT4-based full simulation model to achieve high response to Minimum Ionizing Particles (MIPs) and also good areal uniformity. Cosmic-ray measurements confirms high 1-MIP response for scintillator tiles with an optimized cavity design. Uniformity measurements by scanning the tile area using focused electrons from a beta source show excellent response uniformity. This optimized design is well beyond the requirements for a precision hadron calorimeter.

  14. A Design of Scintillator Tiles Read Out by Surface-Mounted SiPMs for a Future Hadron Calorimeter

    CERN Document Server

    Liu, Yong; Caudron, Julien; Chau, Phi; Krause, Sascha; Masetti, Lucia; Schäfer, Ulrich; Spreckels, Rouven; Tapprogge, Stefan; Wanke, Rainer

    2015-01-01

    Precision calorimetry using highly granular sampling calorimeters is being developed based on the particle flow concept within the CALICE collaboration. One design option of a hadron calorimeter is based on silicon photomultipliers (SiPMs) to detect photons generated in plastic scintillator tiles. Driven by the need of automated mass assembly of around ten million channels stringently required by the high granularity, we developed a design of scintillator tiles directly coupled with surface-mounted SiPMs. A cavity is created in the center of the bottom surface of each tile to provide enough room for the whole SiPM package and to improve collection of the light produced by incident particles penetrating the tile at different positions. The cavity design has been optimized using a GEANT4-based full simulation model to achieve a high response to a Minimum Ionizing Particles (MIP) and also good spatial uniformity. The single-MIP response for scintillator tiles with an optimized cavity design has been measured usi...

  15. Genome-wide association study identifies variants in PMS1 associated with serum ferritin in a Chinese population.

    Science.gov (United States)

    Liao, Ming; Shi, Jianying; Huang, Lirong; Gao, Yong; Tan, Aihua; Wu, Chunlei; Lu, Zheng; Yang, Xiaobo; Zhang, Shijun; Hu, Yanlin; Qin, Xue; Li, Jianling; Chen, Gang; Xu, Jianfeng; Mo, Zengnan; Zhang, Haiying

    2014-01-01

    Only a small proportion of genetic variation in serum ferritin has been explained by variant genetic studies, and genome-wide association study (GWAS) for serum ferritin has not been investigated widely in Chinese population. We aimed at exploring the novel genetic susceptibility to serum ferritin, and performed this two stage GWAS in a healthy Chinese population of 3,495 men aged 20-69 y, including 1,999 unrelated subjects in the first stage and 1,496 independent individuals in the second stage. Serum ferritin was measured with electrochemiluminescence immunoassay, and DNA samples were collected for genotyping. A total of 1,940,243 SNPs were tested by using multivariate linear regression analysis. After adjusting for population stratification, age and BMI, the rs5742933 located in the 5'UTR region of PMS1 gene on chromosome 2 was the most significantly associated with ferritin concentrations (P-combined  = 2.329×10(-10)) (β  =  -0.11, 95% CI: -0.14, -0.07). Moreover, this marker was about 200 kb away from the candidate gene SLC40A1 which is responsible for iron export. PMS1 gene was the novel genetic susceptibility to serum ferritin in Chinese males and its relation to SLC40A1 needs further study.

  16. Mass test of AdvanSiD model ASD-NUV3S-P SiliconPMs for the Pixel Timing Counter of the MEG II experiment

    Science.gov (United States)

    Rossella, M.; Bariani, S.; Barnaba, O.; Cattaneo, P. W.; Cervi, T.; Menegolli, A.; Nardò, R.; Prata, M. C.; Romano, E.; Scagliotti, C.; Simonetta, M.; Vercellati, F.

    2017-02-01

    The MEG II Timing Counter will measure the positron time of arrival with a resolution of 30 ps relying on two arrays of scintillator pixels read out by 6144 Silicon Photomultipliers (SiPMs) from AdvanSiD. They must be characterized, measuring their breakdown voltage, to assure that the gains of the SiPMs of each pixel are as uniform as possible, to maximize the pixel resolution. To do this an automatic test system that can measure sequentially the parameters of 32 devices has been developed.

  17. LaBr3 : Ce and SiPMs for time-of-flight PET: achieving 100 ps coincidence resolving time

    NARCIS (Netherlands)

    Schaart, Dennis R.; Seifert, Stefan; Vinke, Ruud; van Dam, Herman T.; Dendooven, Peter; Löhner, Herbert; Beekman, Freek J.

    2010-01-01

    The use of time-of-flight (TOF) information in positron emission tomography ( PET) enables significant improvement in image noise properties and, therefore, lesion detection. Silicon photomultipliers (SiPMs) are solid-state photosensors that have several advantages over photomultiplier tubes (PMTs).

  18. LaBr3:Ce and SiPMs for time-of-flight PET: achieving 100 ps coincidence resolving time

    NARCIS (Netherlands)

    Schaart, D.R.; Seifert,S.; Vinke, R.; Van Dam, H.T.; Dendooven, P.; Löhner, H.; Beekman, F.J.

    2010-01-01

    The use of time-of-flight (TOF) information in positron emission tomography (PET) enables significant improvement in image noise properties and, therefore, lesion detection. Silicon photomultipliers (SiPMs) are solid-state photosensors that have several advantages over photomultiplier tubes (PMTs).

  19. 20 CFR 411.650 - Is there a process for resolving disputes between ENs that are not State VR agencies and PMs...

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Is there a process for resolving disputes between ENs that are not State VR agencies and PMs, other than disputes on a payment request? 411.650... Managers § 411.650 Is there a process for resolving disputes between ENs that are not State VR agencies and...

  20. VizieR Online Data Catalog: M17 massive pms stars X-shooter spectra (Ramirez-Tannus+, 2017)

    Science.gov (United States)

    Ramirez-Tannus, M. C.; Kaper, L.; de Koter, A.; Tramper, F.; Bik, A.; Ellerbroek, L. E.; Ochsendorf, B. B.; Ramirez-Agudelo, O. H.; Sana, H.

    2017-05-01

    Normalized X-shooter spectra of the PMS and OB stars in M17 studied. The X-shooter spectra were obtained under good weather conditions with seeing ranging from 0.5" and 1" and clear sky. With the exception of the 2012 B289 spectrum and the 2009 B275 science verification spectrum, the spectrograph slit widths used were 1" (UVB, 300-590nm), 0.9" (VIS, 550-1020nm), and 0.4" (NIR, 1000-2480nm), resulting in a spectral resolving power of 5100, 8800, and 11300, respectively. The slit widths for the 2010 B275 observations were 1.6", 0.9", and 0.9" resulting in a resolving power of 3300, 8800, and 5600, respectively. For the 2012 B289 observations we used the 0.8", 0.7", and 0.4" slits corresponding to a resolving power of 6200, 11000, and 11300 for the UVB, VIS, and NIR arms, respectively. The spectra were taken in nodding mode and reduced using the X-shooter pipeline version 2.7.1 running under the ESO Reflex environment version 2.8.4. (2 data files).

  1. Studies on scintillator tiles and surface-mounted SiPMs for the mass assembly of a highly granular hadron calorimeter

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Yong [Institut fuer Physik, Johannes Gutenberg-Universitaet Mainz, Mainz (Germany); Collaboration: CALICE-D-Collaboration

    2016-07-01

    A technological prototype of a highly granular sampling hadron calorimeter (HCAL) based on scintillator tiles and silicon photomultipliers (SiPMs) is being developed within the CALICE collaboration. Driven by the need of an automated mass assembly of around 8 million channels of the final HCAL, we developed a design of scintillator tiles directly coupled to surface-mounted SiPMs and successfully built an HCAL readout unit with 144 channels via mass assembly. Results of extensive performance tests will be shown. Further studies on the characterisation of a novel SiPM with extremely low noise as well as tile design optimisations for the next generation of HCAL readout units will also be presented.

  2. Disposable self-support paper-based multi-anode microbial fuel cell (PMMFC) integrated with power management system (PMS) as the real time "shock" biosensor for wastewater.

    Science.gov (United States)

    Xu, Zhiheng; Liu, Yucheng; Williams, Isaiah; Li, Yan; Qian, Fengyu; Zhang, Hui; Cai, Dingyi; Wang, Lei; Li, Baikun

    2016-11-15

    A paper-based multi-anode microbial fuel cell (PMMFC) integrated with power management system (PMS) was developed as a disposable self-support real-time "shock" biosensor for wastewater. PMMFCs were examined at three types of shocks (chromium, hypochlorite and acetate) in a batch-mode chamber, and exhibited various responses to shock types and concentrations. The power output of PMMFC sensor was four times as the carbon cloth (CC)-based MFCs, indicating the advantage of paper-based anode for bacterial adhesion. The power output was more sensitive than the voltage output under shocks, and thus preventing the false signals. The simulation of power harvest using PMS indicated that PMMFC could accomplish more frequent data transmission than single-anode MFCs (PSMFC) and CC anode MFCs (CCMMFC), making the self-support wastewater monitor and data transmission possible. Compared with traditional MFC sensors, PMMFCs integrated with PMS exhibit the distinct advantages of tight paper-packed structure, short acclimation period, high power output, and high sensitivity to a wide range of shocks, posing a great potential as "disposable self-support shock sensor" for real time in situ monitoring of wastewater quality.

  3. Homologous and homeologous intermolecular gene conversion are not differentially affected by mutations in the DNA damage or the mismatch repair genes RAD1, RAD50, RAD51, RAD52, RAD54, PMS1 and MSH2

    Energy Technology Data Exchange (ETDEWEB)

    Porter, G.; Westmoreland, J.; Priebe, S. [National Institute of Environmental Health Sciences, Research Triangle Park, NC (United States)] [and others

    1996-06-01

    Mismatch repair (MMR) genes or genes involved in both DNA damage repair and homologous recombination might affect homeologous vs. homologous recombination differentially. Spontaneous mitotic gene conversion between a chromosome and a homologous or homeologous donor sequence (14% diverged) on a single copy plasmid was examined in wild-type Saccharomyces cerevisiae strains and in MMR or DNA damage repair mutants. Homologous recombination in rad51, rad52 and rad54 mutants was considerably reduced, while there was little effect of rad1, rad50, pms1 and msh2 null mutations. DNA divergence resulted in no differential effect on recombination rates in the wild type or the mutants; there was only a five- to 10-fold reduction in homeologous relative to homologous recombination regardless of background. Since DNA divergence is known to affect recombination in some systems, we propose that differences in the role of MMR depends on the mode of recombination and/or the level of divergence. Based on analysis of the recombination breakpoints, there is a minimum of three homologous bases required at a recombination junction. A comparison of Rad{sup +} vs. rad52 strains revealed that while all conversion tracts are continuous, elimination of RAD52 leads to the appearance of a novel class of very short conversion tracts. 67 refs., 5 figs., 4 tabs.

  4. Premenstrual Syndrome (PMS)

    Science.gov (United States)

    ... as ginkgo, ginger, chasteberry, evening primrose oil and St. John's wort. However, few scientific studies have found that any ... or interact with other medications you're taking. St. John's wort, for example, reduces the effectiveness of birth control ...

  5. LaBr(3):Ce and SiPMs for time-of-flight PET: achieving 100 ps coincidence resolving time.

    Science.gov (United States)

    Schaart, Dennis R; Seifert, Stefan; Vinke, Ruud; van Dam, Herman T; Dendooven, Peter; Löhner, Herbert; Beekman, Freek J

    2010-04-07

    The use of time-of-flight (TOF) information in positron emission tomography (PET) enables significant improvement in image noise properties and, therefore, lesion detection. Silicon photomultipliers (SiPMs) are solid-state photosensors that have several advantages over photomultiplier tubes (PMTs). SiPMs are small, essentially transparent to 511 keV gamma rays and insensitive to magnetic fields. This enables novel detector designs aimed at e.g. compactness, high resolution, depth-of-interaction (DOI) correction and MRI compatibility. The goal of the present work is to study the timing performance of SiPMs in combination with LaBr(3):Ce(5%), a relatively new scintillator with promising characteristics for TOF-PET. Measurements were performed with two, bare, 3 mm x 3 mm x 5 mm LaBr(3):Ce(5%) crystals, each coupled to a 3 mm x 3 mm SiPM. Using a (22)Na point source placed at various positions in between the two detectors, a coincidence resolving time (CRT) of approximately 100 ps FWHM for 511 keV annihilation photon pairs was achieved, corresponding to a TOF positioning resolution of approximately 15 mm FWHM. At the same time, pulse height spectra with well-resolved full-energy peaks were obtained. To our knowledge this is the best CRT reported for SiPM-based scintillation detectors to date. It is concluded that SiPM-based scintillation detectors can provide timing resolutions at least as good as detectors based on PMTs.

  6. Analog electro-optical readout of SiPMs achieves fast timing required for time-of-flight PET/MR.

    Science.gov (United States)

    Bieniosek, M F; Levin, C S

    2015-05-07

    The design of combined positron emission tomography/magnetic resonance (PET/MR) systems presents a number of challenges to engineers, as it forces the PET system to acquire data in a space constrained environment that is sensitive to electro-magnetic interference and contains high static, radio frequency and gradient fields. In this work we validate fast timing performance of a PET scintillation detector using a potentially very compact, very low power, and MR compatible readout method in which analog silicon photomultipliers (SiPM) signals are transmitted optically away from the MR bore with little or even no additional readout electronics. This analog 'electro-optial' method could reduce the entire PET readout in the MR bore to two compact, low power components (SiPMs and lasers). Our experiments show fast timing performance from analog electro-optical readout with and without pre-amplification. With 3 mm × 3 mm × 20 mm lutetium-yttrium oxyorthosilicate (LYSO) crystals and Excelitas SiPMs the best two-sided fwhm coincident timing resolution achieved was 220 +/- 3 ps in electrical mode, 230 +/- 2 ps in electro-optical with preamp mode, and 253 +/- 2 ps in electro-optical without preamp mode. Timing measurements were also performed with Hamamatsu SiPMs and 3 mm × 3 mm × 5 mm crystals. In the future the timing degradation seen can be further reduced with lower laser noise or improvements SiPM rise time or gain.

  7. LaBr{sub 3}:Ce and SiPMs for time-of-flight PET: achieving 100 ps coincidence resolving time

    Energy Technology Data Exchange (ETDEWEB)

    Schaart, Dennis R; Seifert, Stefan; Van Dam, Herman T; Beekman, Freek J [Delft University of Technology, Radiation Detection and Medical Imaging, Mekelweg 15, 2629 JB Delft (Netherlands); Vinke, Ruud; Dendooven, Peter; Loehner, Herbert [Kernfysisch Versneller Instituut, University of Groningen, Zernikelaan 25, 9747 AA, Groningen (Netherlands)], E-mail: d.r.schaart@tudelft.nl

    2010-04-07

    The use of time-of-flight (TOF) information in positron emission tomography (PET) enables significant improvement in image noise properties and, therefore, lesion detection. Silicon photomultipliers (SiPMs) are solid-state photosensors that have several advantages over photomultiplier tubes (PMTs). SiPMs are small, essentially transparent to 511 keV gamma rays and insensitive to magnetic fields. This enables novel detector designs aimed at e.g. compactness, high resolution, depth-of-interaction (DOI) correction and MRI compatibility. The goal of the present work is to study the timing performance of SiPMs in combination with LaBr{sub 3}:Ce(5%), a relatively new scintillator with promising characteristics for TOF-PET. Measurements were performed with two, bare, 3 mm x 3 mm x 5 mm LaBr{sub 3}:Ce(5%) crystals, each coupled to a 3 mm x 3 mm SiPM. Using a {sup 22}Na point source placed at various positions in between the two detectors, a coincidence resolving time (CRT) of {approx}100 ps FWHM for 511 keV annihilation photon pairs was achieved, corresponding to a TOF positioning resolution of {approx}15 mm FWHM. At the same time, pulse height spectra with well-resolved full-energy peaks were obtained. To our knowledge this is the best CRT reported for SiPM-based scintillation detectors to date. It is concluded that SiPM-based scintillation detectors can provide timing resolutions at least as good as detectors based on PMTs. (note)

  8. Digital signal processing for a thermal neutron detector using ZnS(Ag):6LiF scintillating layers read out with WLS fibers and SiPMs

    OpenAIRE

    Mosset, J. -B.; Stoykov, A.; Greuter, U.; Hildebrandt, M.; Schlumpf, N.

    2015-01-01

    We present a digital signal processing system based on a photon counting approach which we developed for a thermal neutron detector consisting of ZnS(Ag):6LiF scintillating layers read out with WLS fibers and SiPMs. Three digital filters have been evaluated: a moving sum, a moving sum after differentiation and a digital CR-RC^4 filter. The performances of the detector with these filters are presented. A full analog signal processing using a CR-RC^4 filter has been emulated digitally. The dete...

  9. Digital signal processing for a thermal neutron detector using ZnS(Ag):6LiF scintillating layers read out with WLS fibers and SiPMs

    Science.gov (United States)

    Mosset, J.-B.; Stoykov, A.; Greuter, U.; Hildebrandt, M.; Schlumpf, N.

    2016-07-01

    We present a digital signal processing system based on a photon counting approach which we developed for a thermal neutron detector consisting of ZnS(Ag):6LiF scintillating layers read out with WLS fibers and SiPMs. Three digital filters have been evaluated: a moving sum, a moving sum after differentiation and a digital CR-RC4 filter. The performances of the detector with these filters are presented. A full analog signal processing using a CR-RC4 filter has been emulated digitally. The detector performance obtained with this analog approach is compared with the one obtained with the best performing digital approach.

  10. Digital signal processing for a thermal neutron detector using ZnS(Ag):6LiF scintillating layers read out with WLS fibers and SiPMs

    CERN Document Server

    Mosset, J -B; Greuter, U; Hildebrandt, M; Schlumpf, N

    2015-01-01

    We present a digital signal processing system based on a photon counting approach which we developed for a thermal neutron detector consisting of ZnS(Ag):6LiF scintillating layers read out with WLS fibers and SiPMs. Three digital filters have been evaluated: a moving sum, a moving sum after differentiation and a digital CR-RC^4 filter. The performances of the detector with these filters are presented. A full analog signal processing using a CR-RC^4 filter has been emulated digitally. The detector performance obtained with this analog approach is compared with the one obtained with the best performing digital approach.

  11. Ovarian metastasis from uveal melanoma with MLH1/PMS2 protein loss in a patient with germline MLH1 mutated Lynch syndrome: consequence or coincidence?

    Science.gov (United States)

    Lobo, João; Pinto, Carla; Freitas, Micaela; Pinheiro, Manuela; Vizcaino, Rámon; Oliva, Esther; Teixeira, Manuel R; Jerónimo, Carmen; Bartosch, Carla

    2017-03-01

    Currently, uveal melanoma is not considered within the Lynch syndrome tumor spectrum. However, there are studies suggesting a contribution of microsatellite instability in sporadic uveal melanoma tumorigenesis. We report a 45-year-old woman who was referred for genetic counseling due to a family history of Lynch syndrome caused by a MLH1 mutation. She originally underwent enucleation of the right eye secondary to a uveal spindle cell melanoma diagnosed at age 25. The tumor recurred 22 years later presenting as an ovarian metastasis and concurrently a microscopic endometrial endometrioid carcinoma, grade 1/3 was diagnosed. Subsequent studies highlighted that the uveal melanoma showed high microsatellite instability and loss of MLH1 and PMS2 protein expression, with no MLH1 promoter methylation or BRAF mutation. Additionally, a GNAQ mutation was found. We conclude that our patient's uveal melanoma is most likely related to MLH1 germline mutation and thus Lynch syndrome related. To the best of our knowledge, this is the first report of uveal melanoma showing MLH1/PMS2 protein loss in the context of Lynch syndrome.

  12. A new approach for improved time and position measurements for TOF-PET: Time-stamping of the photo-electrons using analogue SiPMs

    CERN Document Server

    Doroud, K

    2017-01-01

    Measurement of the Time-of-Flight (TOF) of the 511 keV gammas brings an important reduction of statistical noise in the PET image, with higher precision time measurements producing clearer images. The common method of coupling a photodetector to scintillating crystals is to have two matching matrices, with a one-to-one coupling between the crystal and the photodetector. We propose a new geometry based on analogue strip SiPMs reading out a scintillator cut into slabs. This technique allows the time stamping of individual photo-electrons and extracts the best time resolution using a specific algorithm. Here we present the results from the first ‘slab module’ test.

  13. SUPLEMENTASI DAUN TORBANGUN (COLEUS AMBOINICUS LOUR UNTUK MENURUNKAN KELUHAN SINDROM PRAMENSTRUASI PADA REMAJA PUTRI (SUPPLEMENTATION OF TORBANGUN LEAVES [COLEUS AMBOINICUS LOUR] IN REDUCING THE COMPLAINST OF PRE-MENSTRUAL SYNDROME [PMS] AMONG TEENAGE G

    Directory of Open Access Journals (Sweden)

    Mazarina Devi

    2013-07-01

    Full Text Available ABSTRACT Background: Torbangun leaves (Coleus ambonicus Lour is one of type of species from Labiatae family which contains a lot of micronutrient and active element which have been examined as beneficial for human health and quality of life. The plants containing iridoid and flavonoid as well as phytochemical which deal with reproduction hormone is applicable to traditional medication toward PMS cases. Methods: The present study was aimed to assess the efficacy of CAL leaves in the management of PMS. An experimental clinical trial was conducted in 35 teenagers with PMS. Three intervention groups were defined: CAL leaves; commercial preparation; and placebo. Participants were followed-up individually for 1 month. Result: The results showed average menarche occurred around age 13 years, with menstruation lasting 5 days. During each successive treatment cycle, participants experienced a lower pain intensity score. Chi Square test, after adjusting each cycle for baseline pain, treatment compliance and other variables, showed that the group receiving CAL extract had significantly reduced pain intensity (p<0.05 compared with commercial preparation and placebo. Conclusion: The torbangun leaves supplement can be used as treatment to relief symptoms of the premenstrual syndrome. [Penel Gizi Makan 2010, 33(2:180-194]   Keywords: Torbangun leaves (Coleus amboinicus Lour, pre-menstrual syndrome (PMS, teenage girls

  14. [Attempts at biotechnical induction of puberty in young female pigs. 2. Effects of various time intervals between one puberty induction with PMS and HCG to the following estrus synchronization on estrus and ovulation in animals about 190 days old].

    Science.gov (United States)

    Bergfeld, J

    1977-01-01

    A biological engineering approach to induce puberty in 125 young female fattening pigs aged 190 days was undertaken on the basis of a mixture of 500 IU PMS (Prolosanserum, Dessau) with 250 IU HCG (Gonabion, Dresden). The injections were made subcutaneously. Pronounced oestrus symptoms were recorded from the external genital organs of 80% of the probands up to ten days after injection, associated with toleration in 52.8% of them. Toleration usually started on the fourth to sixth days after injection. Cycles began to develop in 57.1% up to the next oestrus period. Animals with -/x weight increase per die of 400 g exhibited lower responses. Results in terms of heat and ovulation were lower along with shorter intervals, when oestric synchronisation was undertaken 53, 32, and 17 days after the induction of puberty (20 days Suisynchron, Bernburg; 750 IU PMS).

  15. Automatic sequences

    CERN Document Server

    Haeseler, Friedrich

    2003-01-01

    Automatic sequences are sequences which are produced by a finite automaton. Although they are not random they may look as being random. They are complicated, in the sense of not being not ultimately periodic, they may look rather complicated, in the sense that it may not be easy to name the rule by which the sequence is generated, however there exists a rule which generates the sequence. The concept automatic sequences has special applications in algebra, number theory, finite automata and formal languages, combinatorics on words. The text deals with different aspects of automatic sequences, in particular:· a general introduction to automatic sequences· the basic (combinatorial) properties of automatic sequences· the algebraic approach to automatic sequences· geometric objects related to automatic sequences.

  16. MBM12 A Younger Version of the TW Hydrae Association?

    CERN Document Server

    Wolk, S J; Jayawardhana, R; Hearty, T J; Wolk, Scott J.; Cover, Rebecca T.; Jayawardhana, Ray; Hearty, Thomas J.

    2000-01-01

    We present optical and infrared photometry of stars near the MBM 12 dark cloud. The optical data indicate that there are about 40 candidate pre-main sequence stars in the same area currently occupied by eight bona-fide PMS stars. Analysis of 2MASS data suggests that 60% of PMS candidates have been detected. Some of these show evidence of optically thick disks. Our study of the 2MASS data also reveals a large enhancement of sources within the MBM 12 cloud, indicating that it is still actively forming stars.

  17. Mass accretion rates from multi-band photometry in the Carina Nebula: the case of Trumpler 14

    CERN Document Server

    Beccari, G; Panagia, N; Valenti, E; Carraro, G; Romaniello, M; Zoccali, M; Weidner, C

    2014-01-01

    We present a study of the mass accretion rates of pre-Main Sequence (PMS) stars in the cluster Trumpler 14 (Tr14) in the Carina Nebula. Using optical multi-band photometry we were able to identify 356 PMS stars showing H-alpha excess emission with equivalent width EW(H-alpha)>20\\AA. We interpret this observational feature as indication that these objects are still actively accreting gas from their circumstellar medium. From a comparison of the HR diagram with PMS evolutionary models we derive ages and masses of the PMS stars. We find that most of the PMS objects are younger than 10 Myr with a median age of ~3 Myr. Surprisingly, we also find that ~20% of the mass accreting objects are older than 10 Myr. For each PMS star in Trumpler 14 we determine the mass accretion rate ($\\dot{M}_{acc}$) and discuss its dependence on mass and age. We finally combine the optical photometry with near-IR observations to build the spectral energy distribution (SED) for each PMS star in Tr14. The analysis of the SEDs suggests the...

  18. Estrogenic and progestagenic effects of extracts of Justicia pectoralis Jacq., an herbal medicine from Costa Rica used for the treatment of menopause and PMS.

    Science.gov (United States)

    Locklear, Tracie D; Huang, Yue; Frasor, Jonna; Doyle, Brian J; Perez, Alice; Gomez-Laurito, Jorge; Mahady, Gail B

    2010-07-01

    To investigate the biological activities of Justicia pectoralis Jacq. (Acanthaceae), an herbal medicine used in Costa Rica (CR) for the management of menopausal symptoms and dysmenorrhea. The aerial parts of J. pectoralis were collected, dried and extracted in methanol. To establish possible mechanisms of action of JP for the treatment of menopausal symptoms, the estrogenic and progesterone agonists, and antiinflammatory activities were investigated. The methanol extract (JP-M) was tested in ER and PR binding assays, a COX-2 enzyme inhibition assay, the ERbeta-CALUX assay in U2-OS cells, as well as reporter and endogenous gene assays in MCF-7 K1 cells. The JP-M extract inhibited COX-2 catalytic activity (IC(50) 4.8 microg/mL); bound to both ERalpha and ERbeta (IC(50) 50 microg/mL and 23.1 microg/mL, respectively); induced estrogen-dependent transcription in the ERbeta-CALUX; and bound to the progesterone receptor (IC(50) 22.8 microg/mL). The extract also modulated the expression of endogenous estrogen responsive genes pS2, PR, and PTGES in MCF-7 cells at a concentration of 20 microg/mL. Activation of a 2 ERE-construct in transiently transfected MCF-7 cells by the extract was inhibited by the estrogen receptor antagonist ICI 182,780, indicating that the effects were mediated through the estrogen receptor. Finally, the extract weakly enhanced the proliferation of MCF-7 cells, however this was not statistically significant as compared with DMSO controls. Extracts of J. pectoralis have estrogenic, progestagenic and anti-inflammatory effects, and thus have a plausible mechanism of action, explaining its traditional use for menopause and PMS. Copyright 2010 Elsevier Ireland Ltd. All rights reserved.

  19. Timing and Energy Resolution of new near-UV SiPMs coupled to LaBr3:Ce for TOF-PET

    Science.gov (United States)

    Schmall, Jeffrey P.; Wiener, Rony I.; Surti, Suleman; Ferri, Alessandro; Gola, Alberto; Tarolli, Alessandro; Piemonte, Claudio; Karp, Joel S.

    2014-01-01

    The high light output and fast decay time of LaBr3:Ce scintillation detectors leads to excellent timing performance. To realize the potential of timing resolution with LaBr3:Ce we have investigated the performance with SiPMs, which enable 1-to-1 coupling to individual crystals, and which have been optimized for the near-ultraviolet (NUV) scintillation light emission of LaBr3:Ce. Coincidence timing resolution (CTR) of 100 ps was measured for a 4×4×5 mm3 LaBr3:30%Ce crystal directly coupled to a large-area 4×4 mm2 NUV-SiPM. Results show very little dependence on temperature, in the range of −20° to 20°C, and bias voltage, from 2 V to 5 V over breakdown. Optimal performance was achieved at an over-voltage (OV) range of 3 V – 5 V, at which high gain and high photon detection efficiency are achieved. Though saturation was evident at 511 keV, an energy resolution of 6.8% was measured after correcting for non-linearity. We also measured a CTR of 110 ps for a 4×4×5mm3 LaBr3:5%Ce crystal and 245 ps for a 4×4×30 mm3 LaBr3:5%Ce crystal using the NUV-SIPM. The poorer timing measurement for the 30-mm long crystal is due mainly to a systematic shift in the time pick-off as a function of the depth-of-interaction. The excellent temperature stability, fast rise time, high gain, and low noise of the NUV-SiPM make it a practical and highly appealing photodetector for the readout of a LaBr3:Ce TOF-PET detector. PMID:25530626

  20. Sequence assembly

    DEFF Research Database (Denmark)

    Scheibye-Alsing, Karsten; Hoffmann, S.; Frankel, Annett Maria

    2009-01-01

    Despite the rapidly increasing number of sequenced and re-sequenced genomes, many issues regarding the computational assembly of large-scale sequencing data have remain unresolved. Computational assembly is crucial in large genome projects as well for the evolving high-throughput technologies...

  1. Diversity and Defense-in-depth Analysis of the PMS Based on ALS Platform%先进逻辑系统平台的保护与监测系统的D3分析

    Institute of Scientific and Technical Information of China (English)

    徐智

    2016-01-01

    2013年美国核管会通过了对西屋公司开发的新一代基于现场可编程门阵列技术的1E级先进逻辑系统平台的认证。针对基于该平台所设计的保护与监测系统,依据NUREG/CR 6303的相关要求,进行了多样性和纵深防御要求分析,并按NUREG/CR 7007的方法计算了保护与监测系统的多样性量化值。分析结果表明,新设计的保护与监测系统方案基本满足美国核管会对系统多样性的定量要求,并得出可以不单独设置多样性驱动系统的初步结论。%In 2013,the new generation Class 1E ALS platform based on FPGA technology developed by Westinghouse Electric Company had been approved by US NRC. Aiming at the protection and monitoring system ( PMS) designed based on this platform,in accordance with the requirements of NUREG/CR 6303,the analysis of diversity and defense-in-depth is conducted;and the quantitative value of diversity for PMS is calculated by using the method of NUREG/CR 7007. The results of analysis indicate that the newly designed PMS basically meets the diversity requirements of US NRC,and the preliminary conclusion of eliminating diversity actuation system is obtained.

  2. Genome Sequencing

    DEFF Research Database (Denmark)

    Sato, Shusei; Andersen, Stig Uggerhøj

    2014-01-01

    The current Lotus japonicus reference genome sequence is based on a hybrid assembly of Sanger TAC/BAC, Sanger shotgun and Illumina shotgun sequencing data generated from the Miyakojima-MG20 accession. It covers nearly all expressed L. japonicus genes and has been annotated mainly based on transcr......The current Lotus japonicus reference genome sequence is based on a hybrid assembly of Sanger TAC/BAC, Sanger shotgun and Illumina shotgun sequencing data generated from the Miyakojima-MG20 accession. It covers nearly all expressed L. japonicus genes and has been annotated mainly based...

  3. Dna Sequencing

    Science.gov (United States)

    Tabor, Stanley; Richardson, Charles C.

    1995-04-25

    A method for sequencing a strand of DNA, including the steps off: providing the strand of DNA; annealing the strand with a primer able to hybridize to the strand to give an annealed mixture; incubating the mixture with four deoxyribonucleoside triphosphates, a DNA polymerase, and at least three deoxyribonucleoside triphosphates in different amounts, under conditions in favoring primer extension to form nucleic acid fragments complementory to the DNA to be sequenced; labelling the nucleic and fragments; separating them and determining the position of the deoxyribonucleoside triphosphates by differences in the intensity of the labels, thereby to determine the DNA sequence.

  4. UV/PMS体系硝基氯酚降解动力学及机理研究%Degradation kinetics and mechanisms of chloronitrophenol in UV/PMS system

    Institute of Scientific and Technical Information of China (English)

    周骏; 肖九花; 方长玲; 肖冬雪; 郭耀广; 娄晓祎; 王兆慧; 柳建设

    2016-01-01

    采用紫外光(UV)/单过氧硫酸氢盐(PMS)体系可有效地氧化降解4-氯-2-硝基酚(4C2NP)。考察了溶液 pH 值、底物初始浓度、PMS初始浓度和氯离子、硝酸根离子初始浓度对4C2NP降解效果的影响。在pH2~5时,体系中4C2NP的降解速率并未出现显著差异;随着pH值升高至近中性,其降解过程受到一定程度抑制。初始底物浓度和PMS浓度与体系中4C2NP的降解速率分别呈现负、正相关关系。外加氯离子对4C2NP降解呈现出双重作用,而硝酸盐离子对4C2NP降解抑制作用不显著。脱氯和脱硝过程是4C2NP主要的降解途径。被释放的氯离子会通过自由基反应进行再氯化过程,而脱落的硝基会很快被氧化生成稳定的硝酸盐,从而抑制了硝基的循环过程。最后,根据中间产物推断了4C2NP降解过程的反应机理。%The efficient removal of 4-chloro-2-nitrophenol (4C2NP) in ultraviolet (UV)/peroxymonosulfate (PMS) oxidation system was investigated. The effects of pH, PMS dosage and concentrations of 4C2NP, chloride and nitrate ions on the degradation efficiency of 4C2NP were evaluated. No significant differences in 4C2NP degradation rate were observed at pH 2.0~5.0, but a further increase in pH value would inhibit the substrate decomposition. In addition, PMS dosage positively correlated with degradation rates of 4C2NP, while 4C2NP concentration had a negative effect. A typical dual effect of chloride concentrations on the 4C2NP degradation kinetics was observed, whereas the increasing concentrations of nitrate showed an indistinctively inhibitory effect on 4C2NP degradation. Dechlorination and denitration were the dominant degradation pathways during the oxidative degradation of 4C2NP, followed by the formation of chloride and nitrate ions. The released chloride from chloro groups would be involved in re-chlorination through radical reactions. Nitro groups released would be oxidized to stable nitrate

  5. Progressive star formation in the young galactic super star cluster NGC 3603

    CERN Document Server

    Beccari, Giacomo; De Marchi, Guido; Paresce, Francesco; Young, Erick; Andersen, Morten; Panagia, Nino; Balick, Bruce; Bond, Howard; Calzetti, Daniela; Carollo, C Marcella; Disney, Michael J; Dopita, Michael A; Frogel, Jay A; Hall, Donald N B; Holtzman, Jon A; Kimble, Randy A; McCarthy, Patrick J; O'Connell, Robert W; Saha, Abhijit; Silk, Joseph I; Trauger, John T; Walker, Alistair R; Whitmore, Bradley C; Windhorst, Rogier A

    2010-01-01

    Early release science observations of the cluster NGC3603 with the WFC3 on the refurbished HST allow us to study its recent star formation history. Our analysis focuses on stars with Halpha excess emission, a robust indicator of their pre-main sequence (PMS) accreting status. The comparison with theoretical PMS isochrones shows that 2/3 of the objects with Halpha excess emission have ages from 1 to 10 Myr, with a median value of 3 Myr, while a surprising 1/3 of them are older than 10 Myr. The study of the spatial distribution of these PMS stars allows us to confirm their cluster membership and to statistically separate them from field stars. This result establishes unambiguously for the first time that star formation in and around the cluster has been ongoing for at least 10-20 Myr, at an apparently increasing rate.

  6. Main: Sequences [KOME

    Lifescience Database Archive (English)

    Full Text Available Sequences Nucleotide Sequence Nucleotide sequence of full length cDNA (trimmed sequence) kome_ine_full_seq...uence_db.fasta.zip kome_ine_full_sequence_db.zip kome_ine_full_sequence_db ...

  7. Digital signal processing for a thermal neutron detector using ZnS(Ag):{sup 6}LiF scintillating layers read out with WLS fibers and SiPMs

    Energy Technology Data Exchange (ETDEWEB)

    Mosset, J.-B., E-mail: jean-baptiste.mosset@psi.ch; Stoykov, A.; Greuter, U.; Hildebrandt, M.; Schlumpf, N.

    2016-07-11

    We present a digital signal processing system based on a photon counting approach which we developed for a thermal neutron detector consisting of ZnS(Ag):{sup 6}LiF scintillating layers read out with WLS fibers and SiPMs. Three digital filters have been evaluated: a moving sum, a moving sum after differentiation and a digital CR-RC{sup 4} filter. The performances of the detector with these filters are presented. A full analog signal processing using a CR-RC{sup 4} filter has been emulated digitally. The detector performance obtained with this analog approach is compared with the one obtained with the best performing digital approach. - Highlights: • Application of digital signal processing for a SiPM-based ZnS:6LiF neutron detector. • Optimisation of detector performances with 3 different digital filters. • Comparison with detector performances with a full analog signal processing.

  8. The main sequences of NGC2808: constraints on the early disc accretion scenario

    CERN Document Server

    Cassisi, Santi

    2013-01-01

    [Abridged] A new scenario --early disc accretion-- has been proposed very recently to explain the origin of the multiple population phenomenon in Galactic globular clusters. It envisages the possibility that a fraction of low- and very low-mass cluster stars may accrete the ejecta of interacting massive binary (and possibly also fast rotating massive) stars during the fully convective, pre-main sequence stage, to reproduce the CN and ONa anticorrelations observed among stars in individual clusters. This scenario is assumed to be able to explain the presence (and properties) of the multiple populations in the majority of globular clusters in the Milky Way. Here we have considered the well studied cluster NGC 2808, which displays a triple main sequence with well defined and separate He abundances. Knowledge of these abundances allowed us to put strong constraints on the He mass fraction and amount of matter to be accreted by low-mass pre-main sequence stars. We find that the minimum He mass fraction in the accr...

  9. Star Formation in the Local Group with NIRSpec

    Science.gov (United States)

    De Marchi, Guido; NIRSpec Guaranteed Time Observation Team

    2017-06-01

    I will present a NIRSpec GTO programme showcasing the multi-object spectroscopy capabilities of NIRSpec for stellar studies. We will obtain medium- and high-resolution spectra of hundreds of known pre-main sequence (PMS) stars with different ages hosted in massive starburst clusters in the Galaxy and Magellanic Clouds. These PMS stars were identified from HST photometry as objects with strong Hα excess emission (EW > 10Å). Each cluster contains about 500-1000 such PMS stars in a typical 3’x3’ field, thereby guaranteeing optimal filling of the NIRSpec Micro-Shutter Array. The ultimate scientific goal is to understand the very nature of the mass accretion process, and how the corresponding infall of gas from the circumstellar disc onto the star depends on the mass, age, and metallicity of the PMS object. This study is unique, since spectroscopic studies of PMS objects so far are limited to the solar neighbourhood and no information exists for starburst clusters and for non-solar metallicity.

  10. Large-Scale Distribution of Herbig-Haro Objects in Taurus

    Institute of Scientific and Technical Information of China (English)

    Ke-Feng Sun; Ji Yang; Shao-Guang Luo; Min Wang; Li-Cai Deng; Xu Zhou; Jian-Sheng Chen

    2003-01-01

    We report our new results on Herbig-Haro (HH) objects in the star forming region of Taurus from a wide-field survey with the 60/90 cm Schmidt telescope of the Beijing Astronomical Observatory. This survey using CCD imaging with a narrow band [SⅡ] filter and an intermediate band [BATC10] filter covered approximately 30 square degrees in Taurus. Besides confirming the known HH Objects in the region, we discovered seven new HH candidates, and groups. Six of these are HH 701A-B, HH 702A-D, HH 703, HH 704A-D, HH 705, HH 706 and the seventh is a group, a new component of HH 319, labeled HH 319B-D. Based on the large-scale distribution of pre-main-sequence (PMS) stars in Taurus, we analyze statistically the most probable distance from the HH objects to each PMS star,from which we estimate the typical timescale of these HH objects to be between(1.3 - 2.0) × 104 yrs; and we also obtain the birth rates of HH objects: 0.447±0.198 for Class Ⅰ PMS stars, 0.360±0.222 for Class Ⅱ PMS stars, and -0.148±0.234 for Class Ⅲ PMS stars.

  11. Wide-Field Survey of Emission-line Stars in IC 1396

    CERN Document Server

    Nakano, M; Watanabe, M; Fukuda, N; Ishihara, D; Ueno, M

    2012-01-01

    We have made an extensive survey of emission-line stars in the IC 1396 HII region to investigate the low-mass population of pre-main sequence (PMS) stars. A total of 639 H-alpha emission-line stars were detected in an area of 4.2 deg^2 and their i'-photometry was measured. Their spatial distribution exhibits several aggregates near the elephant trunk globule (Rim A) and bright-rimmed clouds at the edge of the HII region (Rim B and SFO 37, 38, 39, 41), and near HD 206267, which is the main exciting star of the HII region. Based on the extinction estimated from the near-infrared (NIR) color-color diagram, we have selected pre-main sequence star candidates associated with IC 1396. The age and mass were derived from the extinction corrected color-magnitude diagram and theoretical pre-main sequence tracks. Most of our PMS candidates have ages of < 3 Myr and masses of 0.2-0.6 Mo. Although it appears that only a few stars were formed in the last 1 Myr in the east region of the exciting star, the age difference am...

  12. State of the art timing in TOF-PET detectors with LuAG, GAGG and L(Y)SO scintillators of various sizes coupled to FBK-SiPMs

    CERN Document Server

    Gundacker, S.; Auffray, E.; Ferri, A.; Gola, A.; Nemallapudi, M.V.; Paternoster, G.; Piemonte, C.; Lecoq, P.

    2016-01-01

    Time of flight (TOF) in positron emission tomography (PET) has experienced a revival of interest after its first introduction in the eighties. This is due to a significant progress in solid state photodetectors (SiPMs) and newly developed scintillators (LSO and its derivatives). Latest developments at Fondazione Bruno Kessler (FBK) lead to the NUV-HD SiPM with a very high photon detection efficiency of around 55%. Despite the large area of 4×4 mm2 it achieves a good single photon time resolution (SPTR) of 180±5ps FWHM. Coincidence time resolution (CTR) measurements using LSO:Ce codoped with Ca scintillators yield best values of 73±2ps FWHM for 2×2×3 mm3 and 117±3ps for 2×2×20 mm3 crystal sizes. Increasing the crystal cross-section from 2×2 mm2 to 3×3 mm2 a non negligible CTR deterioration of approximately 7ps FWHM is observed. Measurements with LSO:Ce codoped Ca and LYSO:Ce scintillators with various cross-sections (1×1 mm2 - 4×4 mm2) and lengths (3mm - 30mm) will be a basis for discussing on how ...

  13. Identification of IncA/C Plasmid Replication and Maintenance Genes and Development of a Plasmid Multilocus Sequence Typing Scheme.

    Science.gov (United States)

    Hancock, Steven J; Phan, Minh-Duy; Peters, Kate M; Forde, Brian M; Chong, Teik Min; Yin, Wai-Fong; Chan, Kok-Gan; Paterson, David L; Walsh, Timothy R; Beatson, Scott A; Schembri, Mark A

    2017-02-01

    Plasmids of incompatibility group A/C (IncA/C) are becoming increasingly prevalent within pathogenic Enterobacteriaceae They are associated with the dissemination of multiple clinically relevant resistance genes, including blaCMY and blaNDM Current typing methods for IncA/C plasmids offer limited resolution. In this study, we present the complete sequence of a blaNDM-1-positive IncA/C plasmid, pMS6198A, isolated from a multidrug-resistant uropathogenic Escherichia coli strain. Hypersaturated transposon mutagenesis, coupled with transposon-directed insertion site sequencing (TraDIS), was employed to identify conserved genetic elements required for replication and maintenance of pMS6198A. Our analysis of TraDIS data identified roles for the replicon, including repA, a toxin-antitoxin system; two putative partitioning genes, parAB; and a putative gene, 053 Construction of mini-IncA/C plasmids and examination of their stability within E. coli confirmed that the region encompassing 053 contributes to the stable maintenance of IncA/C plasmids. Subsequently, the four major maintenance genes (repA, parAB, and 053) were used to construct a new plasmid multilocus sequence typing (PMLST) scheme for IncA/C plasmids. Application of this scheme to a database of 82 IncA/C plasmids identified 11 unique sequence types (STs), with two dominant STs. The majority of blaNDM-positive plasmids examined (15/17; 88%) fall into ST1, suggesting acquisition and subsequent expansion of this blaNDM-containing plasmid lineage. The IncA/C PMLST scheme represents a standardized tool to identify, track, and analyze the dissemination of important IncA/C plasmid lineages, particularly in the context of epidemiological studies. Copyright © 2017 American Society for Microbiology.

  14. Classifying Genomic Sequences by Sequence Feature Analysis

    Institute of Scientific and Technical Information of China (English)

    Zhi-Hua Liu; Dian Jiao; Xiao Sun

    2005-01-01

    Traditional sequence analysis depends on sequence alignment. In this study, we analyzed various functional regions of the human genome based on sequence features, including word frequency, dinucleotide relative abundance, and base-base correlation. We analyzed the human chromosome 22 and classified the upstream,exon, intron, downstream, and intergenic regions by principal component analysis and discriminant analysis of these features. The results show that we could classify the functional regions of genome based on sequence feature and discriminant analysis.

  15. Main: Sequences [KOME

    Lifescience Database Archive (English)

    Full Text Available Sequences Amino Acid Sequence Amino Acid sequence of full length cDNA (Longest ORF) kome_ine_full_seq...uence_amino_db.fasta.zip kome_ine_full_sequence_amino_db.zip kome_ine_full_sequence_amino_db ...

  16. Shotgun protein sequencing.

    Energy Technology Data Exchange (ETDEWEB)

    Faulon, Jean-Loup Michel; Heffelfinger, Grant S.

    2009-06-01

    A novel experimental and computational technique based on multiple enzymatic digestion of a protein or protein mixture that reconstructs protein sequences from sequences of overlapping peptides is described in this SAND report. This approach, analogous to shotgun sequencing of DNA, is to be used to sequence alternative spliced proteins, to identify post-translational modifications, and to sequence genetically engineered proteins.

  17. State of the art timing in TOF-PET detectors with LuAG, GAGG and L(Y)SO scintillators of various sizes coupled to FBK-SiPMs

    Science.gov (United States)

    Gundacker, S.; Acerbi, F.; Auffray, E.; Ferri, A.; Gola, A.; Nemallapudi, M. V.; Paternoster, G.; Piemonte, C.; Lecoq, P.

    2016-08-01

    Time of flight (TOF) in positron emission tomography (PET) has experienced a revival of interest after its first introduction in the eighties. This is due to a significant progress in solid state photodetectors (SiPMs) and newly developed scintillators (LSO and its derivatives). Latest developments at Fondazione Bruno Kessler (FBK) lead to the NUV-HD SiPM with a very high photon detection efficiency of around 55%. Despite the large area of 4×4 mm2 it achieves a good single photon time resolution (SPTR) of 180±5ps FWHM. Coincidence time resolution (CTR) measurements using LSO:Ce codoped with Ca scintillators yield best values of 73±2ps FWHM for 2×2×3 mm3 and 117±3ps for 2×2×20 mm3 crystal sizes. Increasing the crystal cross-section from 2×2 mm2 to 3×3 mm2 a non negligible CTR deterioration of approximately 7ps FWHM is observed. Measurements with LSO:Ce codoped Ca and LYSO:Ce scintillators with various cross-sections (1×1 mm2 - 4×4 mm2) and lengths (3mm - 30mm) will be a basis for discussing on how the crystal geometry affects timing in TOF-PET. Special attention is given to SiPM parameters, e.g. SPTR and optical crosstalk, and their measured dependency on the crystal cross-section. Additionally, CTR measurements with LuAG:Ce, LuAG:Pr and GGAG:Ce samples are presented and the results are interpreted in terms of their scintillation properties, e.g. rise time, decay time, light yield and emission spectra.

  18. Sequence Read Archive (SRA)

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Sequence Read Archive (SRA) stores raw sequencing data from the next generation of sequencing platforms including Roche 454 GS System®, Illumina Genome...

  19. Multimodal sequence learning.

    Science.gov (United States)

    Kemény, Ferenc; Meier, Beat

    2016-02-01

    While sequence learning research models complex phenomena, previous studies have mostly focused on unimodal sequences. The goal of the current experiment is to put implicit sequence learning into a multimodal context: to test whether it can operate across different modalities. We used the Task Sequence Learning paradigm to test whether sequence learning varies across modalities, and whether participants are able to learn multimodal sequences. Our results show that implicit sequence learning is very similar regardless of the source modality. However, the presence of correlated task and response sequences was required for learning to take place. The experiment provides new evidence for implicit sequence learning of abstract conceptual representations. In general, the results suggest that correlated sequences are necessary for implicit sequence learning to occur. Moreover, they show that elements from different modalities can be automatically integrated into one unitary multimodal sequence.

  20. Coordinate cytokine regulatory sequences

    Science.gov (United States)

    Frazer, Kelly A.; Rubin, Edward M.; Loots, Gabriela G.

    2005-05-10

    The present invention provides CNS sequences that regulate the cytokine gene expression, expression cassettes and vectors comprising or lacking the CNS sequences, host cells and non-human transgenic animals comprising the CNS sequences or lacking the CNS sequences. The present invention also provides methods for identifying compounds that modulate the functions of CNS sequences as well as methods for diagnosing defects in the CNS sequences of patients.

  1. Massive star formation by accretion. II. Rotation: how to circumvent the angular momentum barrier?

    Science.gov (United States)

    Haemmerlé, L.; Eggenberger, P.; Meynet, G.; Maeder, A.; Charbonnel, C.; Klessen, R. S.

    2017-06-01

    Context. Rotation plays a key role in the star-formation process, from pre-stellar cores to pre-main-sequence (PMS) objects. Understanding the formation of massive stars requires taking into account the accretion of angular momentum during their PMS phase. Aims: We study the PMS evolution of objects destined to become massive stars by accretion, focusing on the links between the physical conditions of the environment and the rotational properties of young stars. In particular, we look at the physical conditions that allow the production of massive stars by accretion. Methods: We present PMS models computed with a new version of the Geneva Stellar Evolution code self-consistently including accretion and rotation according to various accretion scenarios for mass and angular momentum. We describe the internal distribution of angular momentum in PMS stars accreting at high rates and we show how the various physical conditions impact their internal structures, evolutionary tracks, and rotation velocities during the PMS and the early main sequence. Results: We find that the smooth angular momentum accretion considered in previous studies leads to an angular momentum barrier and does not allow the formation of massive stars by accretion. A braking mechanism is needed in order to circumvent this angular momentum barrier. This mechanism has to be efficient enough to remove more than two thirds of the angular momentum from the inner accretion disc. Due to the weak efficiency of angular momentum transport by shear instability and meridional circulation during the accretion phase, the internal rotation profiles of accreting stars reflect essentially the angular momentum accretion history. As a consequence, careful choice of the angular momentum accretion history allows circumvention of any limitation in mass and velocity, and production of stars of any mass and velocity compatible with structure equations.

  2. 23 CFR 500.106 - PMS.

    Science.gov (United States)

    2010-04-01

    ... process that provides information for use in implementing cost-effective pavement reconstruction, rehabilitation, and preventative maintenance programs and that results in pavements designed to accommodate... the “AASHTO Guidelines for Pavement Management Systems.” 1 1 AASHTO Guidelines for Pavement...

  3. Classifying the embedded young stellar population in Perseus and Taurus and the LOMASS database

    DEFF Research Database (Denmark)

    Carney, M. T.; Ylldlz, U. A.; Mottram, J. C.

    2016-01-01

    Context. The classification of young stellar objects (YSOs) is typically done using the infrared spectral slope or bolometric temperature, but either can result in contamination of samples. More accurate methods to determine the evolutionary stage of YSOs will improve the reliability of statistics...... in the protostellar envelopes. The spatial concentration of HCO+J = 4-3 and 850 μm dust emission are used to classify the embedded nature of YSOs. Results. Approximately 30% of Class 0+I sources in Perseus and Taurus are not Stage I, but are likely to be more evolved Stage II pre-main sequence (PMS) stars with disks...

  4. X-ray observations of eight young open star clusters : I. Membership and X-ray Luminosity

    CERN Document Server

    Bhatt, Himali; Singh, K P; Sagar, Ram; Kumar, Brijesh

    2013-01-01

    We present a detailed investigation of X-ray source contents of eight young open clusters with ages between 4 to 46 Myr using archival X-ray data from XMM-Newton. The probable cluster memberships of the X-ray sources have been established on the basis of multi-wavelength archival data, and samples of 152 pre-main sequence (PMS) low mass ( 10 M_\\odot) stars have been generated. X-ray spectral analyses of high mass stars reveal the presence of high temperature plasma with temperature <2 keV, and mean L_X/L_{bol} of 10^{-6.9}. In the case of PMS low mass stars, the plasma temperatures have been found to be in the range of 0.2 keV to 3 keV with a median value of ~1.3 keV, with no significant difference in plasma temperatures during their evolution from 4 to 46 Myr. The X-ray luminosity distributions of the PMS low mass stars have been found to be similar in the young star clusters under study. This may suggest a nearly uniform X-ray activity in the PMS low mass stars of ages ~4--14 Myr. These observed values o...

  5. Wide-field Survey of Emission-line Stars in IC 1396

    Science.gov (United States)

    Nakano, M.; Sugitani, K.; Watanabe, M.; Fukuda, N.; Ishihara, D.; Ueno, M.

    2012-03-01

    We have made an extensive survey of emission-line stars in the IC 1396 H II region to investigate the low-mass population of pre-main-sequence (PMS) stars. A total of 639 Hα emission-line stars were detected in an area of 4.2 deg2 and their i' photometry was measured. Their spatial distribution exhibits several aggregates near the elephant trunk globule (Rim A) and bright-rimmed clouds at the edge of the H II region (Rim B and SFO 37, 38, 39, 41), and near HD 206267, which is the main exciting star of the H II region. Based on the extinction estimated from the near-infrared color-color diagram, we have selected PMS star candidates associated with IC 1396. The age and mass were derived from the extinction-corrected color-magnitude diagram and theoretical PMS tracks. Most of our PMS candidates have ages of low-mass stars for 10 Myr. The birth of the exciting star could be the late stage of slow but contiguous star formation in the natal molecular cloud. It may have triggered the formation of many low-mass stars at the dense inhomogeneity in and around the H II region by a radiation-driven implosion.

  6. Genome Sequence Databases (Overview): Sequencing and Assembly

    Energy Technology Data Exchange (ETDEWEB)

    Lapidus, Alla L.

    2009-01-01

    From the date its role in heredity was discovered, DNA has been generating interest among scientists from different fields of knowledge: physicists have studied the three dimensional structure of the DNA molecule, biologists tried to decode the secrets of life hidden within these long molecules, and technologists invent and improve methods of DNA analysis. The analysis of the nucleotide sequence of DNA occupies a special place among the methods developed. Thanks to the variety of sequencing technologies available, the process of decoding the sequence of genomic DNA (or whole genome sequencing) has become robust and inexpensive. Meanwhile the assembly of whole genome sequences remains a challenging task. In addition to the need to assemble millions of DNA fragments of different length (from 35 bp (Solexa) to 800 bp (Sanger)), great interest in analysis of microbial communities (metagenomes) of different complexities raises new problems and pushes some new requirements for sequence assembly tools to the forefront. The genome assembly process can be divided into two steps: draft assembly and assembly improvement (finishing). Despite the fact that automatically performed assembly (or draft assembly) is capable of covering up to 98% of the genome, in most cases, it still contains incorrectly assembled reads. The error rate of the consensus sequence produced at this stage is about 1/2000 bp. A finished genome represents the genome assembly of much higher accuracy (with no gaps or incorrectly assembled areas) and quality ({approx}1 error/10,000 bp), validated through a number of computer and laboratory experiments.

  7. Contamination of sequence databases with adaptor sequences

    Energy Technology Data Exchange (ETDEWEB)

    Yoshikawa, Takeo; Sanders, A.R.; Detera-Wadleigh, S.D. [National Institute of Mental Health, Bethesda, MD (United States)

    1997-02-01

    Because of the exponential increase in the amount of DNA sequences being added to the public databases on a daily basis, it has become imperative to identify sources of contamination rapidly. Previously, contaminations of sequence databases have been reported to alert the scientific community to the problem. These contaminations can be divided into two categories. The first category comprises host sequences that have been difficult for submitters to manage or control. Examples include anomalous sequences derived from Escherichia coli, which are inserted into the chromosomes (and plasmids) of the bacterial hosts. Insertion sequences are highly mobile and are capable of transposing themselves into plasmids during cloning manipulation. Another example of the first category is the infection with yeast genomic DNA or with bacterial DNA of some commercially available cDNA libraries from Clontech. The second category of database contamination is due to the inadvertent inclusion of nonhost sequences. This category includes incorporation of cloning-vector sequences and multicloning sites in the database submission. M13-derived artifacts have been common, since M13-based vectors have been widely used for subcloning DNA fragments. Recognizing this problem, the National Center for Biotechnology Information (NCBI) started to screen, in April 1994, all sequences directly submitted to GenBank, against a set of vector data retrieved from GenBank by use of key-word searches, such as {open_quotes}vector.{close_quotes} In this report, we present evidence for another sequence artifact that is widespread but that, to our knowledge, has not yet been reported. 11 refs., 1 tab.

  8. Automated DNA Sequencing System

    Energy Technology Data Exchange (ETDEWEB)

    Armstrong, G.A.; Ekkebus, C.P.; Hauser, L.J.; Kress, R.L.; Mural, R.J.

    1999-04-25

    Oak Ridge National Laboratory (ORNL) is developing a core DNA sequencing facility to support biological research endeavors at ORNL and to conduct basic sequencing automation research. This facility is novel because its development is based on existing standard biology laboratory equipment; thus, the development process is of interest to the many small laboratories trying to use automation to control costs and increase throughput. Before automation, biology Laboratory personnel purified DNA, completed cycle sequencing, and prepared 96-well sample plates with commercially available hardware designed specifically for each step in the process. Following purification and thermal cycling, an automated sequencing machine was used for the sequencing. A technician handled all movement of the 96-well sample plates between machines. To automate the process, ORNL is adding a CRS Robotics A- 465 arm, ABI 377 sequencing machine, automated centrifuge, automated refrigerator, and possibly an automated SpeedVac. The entire system will be integrated with one central controller that will direct each machine and the robot. The goal of this system is to completely automate the sequencing procedure from bacterial cell samples through ready-to-be-sequenced DNA and ultimately to completed sequence. The system will be flexible and will accommodate different chemistries than existing automated sequencing lines. The system will be expanded in the future to include colony picking and/or actual sequencing. This discrete event, DNA sequencing system will demonstrate that smaller sequencing labs can achieve cost-effective the laboratory grow.

  9. Anomaly Detection in Sequences

    Data.gov (United States)

    National Aeronautics and Space Administration — We present a set of novel algorithms which we call sequenceMiner, that detect and characterize anomalies in large sets of high-dimensional symbol sequences that...

  10. DNA sequencing conference, 2

    Energy Technology Data Exchange (ETDEWEB)

    Cook-Deegan, R.M. [Georgetown Univ., Kennedy Inst. of Ethics, Washington, DC (United States); Venter, J.C. [National Inst. of Neurological Disorders and Strokes, Bethesda, MD (United States); Gilbert, W. [Harvard Univ., Cambridge, MA (United States); Mulligan, J. [Stanford Univ., CA (United States); Mansfield, B.K. [Oak Ridge National Lab., TN (United States)

    1991-06-19

    This conference focused on DNA sequencing, genetic linkage mapping, physical mapping, informatics and bioethics. Several were used to study this sequencing and mapping. This article also discusses computer hardware and software aiding in the mapping of genes.

  11. Roles of repetitive sequences

    Energy Technology Data Exchange (ETDEWEB)

    Bell, G.I.

    1991-12-31

    The DNA of higher eukaryotes contains many repetitive sequences. The study of repetitive sequences is important, not only because many have important biological function, but also because they provide information on genome organization, evolution and dynamics. In this paper, I will first discuss some generic effects that repetitive sequences will have upon genome dynamics and evolution. In particular, it will be shown that repetitive sequences foster recombination among, and turnover of, the elements of a genome. I will then consider some examples of repetitive sequences, notably minisatellite sequences and telomere sequences as examples of tandem repeats, without and with respectively known function, and Alu sequences as an example of interspersed repeats. Some other examples will also be considered in less detail.

  12. Roles of repetitive sequences

    Energy Technology Data Exchange (ETDEWEB)

    Bell, G.I.

    1991-12-31

    The DNA of higher eukaryotes contains many repetitive sequences. The study of repetitive sequences is important, not only because many have important biological function, but also because they provide information on genome organization, evolution and dynamics. In this paper, I will first discuss some generic effects that repetitive sequences will have upon genome dynamics and evolution. In particular, it will be shown that repetitive sequences foster recombination among, and turnover of, the elements of a genome. I will then consider some examples of repetitive sequences, notably minisatellite sequences and telomere sequences as examples of tandem repeats, without and with respectively known function, and Alu sequences as an example of interspersed repeats. Some other examples will also be considered in less detail.

  13. sequenceMiner algorithm

    Data.gov (United States)

    National Aeronautics and Space Administration — Detecting and describing anomalies in large repositories of discrete symbol sequences. sequenceMiner has been open-sourced! Download the file below to try it out....

  14. Enhanced virome sequencing using targeted sequence capture.

    Science.gov (United States)

    Wylie, Todd N; Wylie, Kristine M; Herter, Brandi N; Storch, Gregory A

    2015-12-01

    Metagenomic shotgun sequencing (MSS) is an important tool for characterizing viral populations. It is culture independent, requires no a priori knowledge of the viruses in the sample, and may provide useful genomic information. However, MSS can lack sensitivity and may yield insufficient data for detailed analysis. We have created a targeted sequence capture panel, ViroCap, designed to enrich nucleic acid from DNA and RNA viruses from 34 families that infect vertebrate hosts. A computational approach condensed ∼1 billion bp of viral reference sequence into <200 million bp of unique, representative sequence suitable for targeted sequence capture. We compared the effectiveness of detecting viruses in standard MSS versus MSS following targeted sequence capture. First, we analyzed two sets of samples, one derived from samples submitted to a diagnostic virology laboratory and one derived from samples collected in a study of fever in children. We detected 14 and 18 viruses in the two sets, comprising 19 genera from 10 families, with dramatic enhancement of genome representation following capture enrichment. The median fold-increases in percentage viral reads post-capture were 674 and 296. Median breadth of coverage increased from 2.1% to 83.2% post-capture in the first set and from 2.0% to 75.6% in the second set. Next, we analyzed samples containing a set of diverse anellovirus sequences and demonstrated that ViroCap could be used to detect viral sequences with up to 58% variation from the references used to select capture probes. ViroCap substantially enhances MSS for a comprehensive set of viruses and has utility for research and clinical applications.

  15. DNA sequences encoding erythropoietin

    Energy Technology Data Exchange (ETDEWEB)

    Lin, F.K.

    1987-10-27

    A purified and isolated DNA sequence is described consisting essentially of a DNA sequence encoding a polypeptide having an amino acid sequence sufficiently duplicative of that of erythropoietin to allow possession of the biological property of causing bone marrow cells to increase production of reticulocytes and red blood cells, and to increase hemoglobin synthesis or iron uptake.

  16. Low autocorrelation binary sequences

    Science.gov (United States)

    Packebusch, Tom; Mertens, Stephan

    2016-04-01

    Binary sequences with minimal autocorrelations have applications in communication engineering, mathematics and computer science. In statistical physics they appear as groundstates of the Bernasconi model. Finding these sequences is a notoriously hard problem, that so far can be solved only by exhaustive search. We review recent algorithms and present a new algorithm that finds optimal sequences of length N in time O(N {1.73}N). We computed all optimal sequences for N≤slant 66 and all optimal skewsymmetric sequences for N≤slant 119.

  17. Repdigits in -Lucas Sequences

    Indian Academy of Sciences (India)

    Jhon J J Bravo; Florian Luca

    2014-05-01

    For an integer ≥ 2, let $(L_n^{(k)})_n$ be the -Lucas sequence which starts with $0,\\ldots,0,2,1$ ( terms) and each term afterwards is the sum of the preceding terms. In 2000, Luca (Port. Math. 57(2) 2000 243-254) proved that 11 is the largest number with only one distinct digit (the so-called repdigit) in the sequence $(L_n^{(2)})_n$. In this paper, we address a similar problem in the family of -Lucas sequences. We also show that the -Lucas sequences have similar properties to those of -Fibonacci sequences and occur in formulae simultaneously with the latter.

  18. On Maximal Green Sequences

    CERN Document Server

    Brüstle, Thomas; Pérotin, Matthieu

    2012-01-01

    Maximal green sequences are particular sequences of quiver mutations which were introduced by Keller in the context of quantum dilogarithm identities and independently by Cecotti-Cordova-Vafa in the context of supersymmetric gauge theory. Our aim is to initiate a systematic study of these sequences from a combinatorial point of view. Interpreting maximal green sequences as paths in various natural posets arising in representation theory, we prove the finiteness of the number of maximal green sequences for cluster finite quivers, affine quivers and acyclic quivers with at most three vertices. We also give results concerning the possible numbers and lengths of these maximal green sequences. Finally we describe an algorithm for computing maximal green sequences for arbitrary valued quivers which we used to obtain numerous explicit examples that we present.

  19. Next-generation sequencing

    DEFF Research Database (Denmark)

    Rieneck, Klaus; Bak, Mads; Jønson, Lars

    2013-01-01

    the feasibility of predicting the fetal KEL1 phenotype using next-generation sequencing (NGS) technology. STUDY DESIGN AND METHODS: The KEL1/2 single-nucleotide polymorphism was polymerase chain reaction (PCR) amplified with one adjoining base, and the PCR product was sequenced using a genome analyzer (GAIIx......, Illumina); several millions of PCR sequences were analyzed. RESULTS: The results demonstrated the feasibility of diagnosing the fetal KEL1 or KEL2 blood group from cell-free DNA purified from maternal plasma. CONCLUSION: This method requires only one primer pair, and the large amount of sequence...

  20. Hardware bitstream sequence recognizer

    OpenAIRE

    Karpin, Oleksandr; Sokil, Volodymyr

    2009-01-01

    This paper describes how to implement in hardware a bistream sequence recognizer using the PSoC Pseudo Random Sequence Generator (PRS) User Module. The PRS can be used in digital communication systems with the serial data interface for automatic preamble detection and extraction, control words selection, etc.

  1. Cosmetology: Scope and Sequence.

    Science.gov (United States)

    Nashville - Davidson County Metropolitan Public Schools, TN.

    This scope and sequence guide, developed for a cosmetology vocational education program, represents an initial step in the development of a systemwide articulated curriculum sequence for all vocational programs within the Metropolitan Nashville Public School System. It was developed as a result of needs expressed by teachers, parents, and the…

  2. DNA sequencing by CE.

    Science.gov (United States)

    Karger, Barry L; Guttman, András

    2009-06-01

    Sequencing of human and other genomes has been at the center of interest in the biomedical field over the past several decades and is now leading toward an era of personalized medicine. During this time, DNA-sequencing methods have evolved from the labor-intensive slab gel electrophoresis, through automated multiCE systems using fluorophore labeling with multispectral imaging, to the "next-generation" technologies of cyclic-array, hybridization based, nanopore and single molecule sequencing. Deciphering the genetic blueprint and follow-up confirmatory sequencing of Homo sapiens and other genomes were only possible with the advent of modern sequencing technologies that were a result of step-by-step advances with a contribution of academics, medical personnel and instrument companies. While next-generation sequencing is moving ahead at breakneck speed, the multicapillary electrophoretic systems played an essential role in the sequencing of the Human Genome, the foundation of the field of genomics. In this prospective, we wish to overview the role of CE in DNA sequencing based in part of several of our articles in this journal.

  3. Sequencing the maize genome.

    Science.gov (United States)

    Martienssen, Robert A; Rabinowicz, Pablo D; O'Shaughnessy, Andrew; McCombie, W Richard

    2004-04-01

    Sequencing of complex genomes can be accomplished by enriching shotgun libraries for genes. In maize, gene-enrichment by copy-number normalization (high C(0)t) and methylation filtration (MF) have been used to generate up to two-fold coverage of the gene-space with less than 1 million sequencing reads. Simulations using sequenced bacterial artificial chromosome (BAC) clones predict that 5x coverage of gene-rich regions, accompanied by less than 1x coverage of subclones from BAC contigs, will generate high-quality mapped sequence that meets the needs of geneticists while accommodating unusually high levels of structural polymorphism. By sequencing several inbred strains, we propose a strategy for capturing this polymorphism to investigate hybrid vigor or heterosis.

  4. RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

    OpenAIRE

    Shibata, Kazuhiro; Itoh, Masayoshi; Aizawa, Katsunori; Nagaoka, Sumiharu; Sasaki, Nobuya; Carninci, Piero; Konno, Hideaki; AKIYAMA, Junichi; Nishi, Katsuo; Kitsunai, Tokuji; Tashiro, Hideo; Itoh, Mari; Sumi, Noriko; Ishii, Yoshiyuki; Nakamura, Shin

    2000-01-01

    The RIKEN high-throughput 384-format sequencing pipeline (RISA system) including a 384-multicapillary sequencer (the so-called RISA sequencer) was developed for the RIKEN mouse encyclopedia project. The RISA system consists of colony picking, template preparation, sequencing reaction, and the sequencing process. A novel high-throughput 384-format capillary sequencer system (RISA sequencer system) was developed for the sequencing process. This system consists of a 384-multicapillary auto seque...

  5. HIV Sequence Compendium 2015

    Energy Technology Data Exchange (ETDEWEB)

    Foley, Brian Thomas [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Leitner, Thomas Kenneth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Apetrei, Cristian [Univ. of Pittsburgh, PA (United States); Hahn, Beatrice [Univ. of Pennsylvania, Philadelphia, PA (United States); Mizrachi, Ilene [National Center for Biotechnology Information, Bethesda, MD (United States); Mullins, James [Univ. of Washington, Seattle, WA (United States); Rambaut, Andrew [Univ. of Edinburgh, Scotland (United Kingdom); Wolinsky, Steven [Northwestern Univ., Evanston, IL (United States); Korber, Bette Tina Marie [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-10-05

    This compendium is an annual printed summary of the data contained in the HIV sequence database. We try to present a judicious selection of the data in such a way that it is of maximum utility to HIV researchers. Each of the alignments attempts to display the genetic variability within the different species, groups and subtypes of the virus. This compendium contains sequences published before January 1, 2015. Hence, though it is published in 2015 and called the 2015 Compendium, its contents correspond to the 2014 curated alignments on our website. The number of sequences in the HIV database is still increasing. In total, at the end of 2014, there were 624,121 sequences in the HIV Sequence Database, an increase of 7% since the previous year. This is the first year that the number of new sequences added to the database has decreased compared to the previous year. The number of near complete genomes (>7000 nucleotides) increased to 5834 by end of 2014. However, as in previous years, the compendium alignments contain only a fraction of these. A more complete version of all alignments is available on our website, http://www.hiv.lanl.gov/ content/sequence/NEWALIGN/align.html As always, we are open to complaints and suggestions for improvement. Inquiries and comments regarding the compendium should be addressed to seq-info@lanl.gov.

  6. Phylogenetic Trees From Sequences

    Science.gov (United States)

    Ryvkin, Paul; Wang, Li-San

    In this chapter, we review important concepts and approaches for phylogeny reconstruction from sequence data.We first cover some basic definitions and properties of phylogenetics, and briefly explain how scientists model sequence evolution and measure sequence divergence. We then discuss three major approaches for phylogenetic reconstruction: distance-based phylogenetic reconstruction, maximum parsimony, and maximum likelihood. In the third part of the chapter, we review how multiple phylogenies are compared by consensus methods and how to assess confidence using bootstrapping. At the end of the chapter are two sections that list popular software packages and additional reading.

  7. Sejong Open Cluster Survey (SOS). III. The Young Open Cluster NGC 1893 in the H II Region W8

    CERN Document Server

    Lim, Beomdu; Kim, Jinyoung S; Bessell, Michael S; Park, Byeong-Gon

    2014-01-01

    We present a UBV I and H alpha photometric study of the young open cluster NGC 1893 in the H II region W8 (IC 410 or Sh 2-236). A total of 65 early-type members are selected from photometric diagrams. A mean reddening of the stars is = 0.563 +/- 0.083 mag. The published photometric data in the near- and mid-infrared passbands are used to test the reddening law toward the cluster, and we confirm that the reddening law is normal (R_V = 3.1). Zero-age main sequence fitting gives a distance modulus of V_0 - M_V = 12.7 +/- 0.2 mag, equivalent to 3.5 +/- 0.3 kpc. From H alpha photometry 125 H alpha emission stars and candidates are identified as pre-main sequence (PMS). The lists of young stellar objects and X-ray sources published by previous studies allow us to select a large number of PMS members down to 1 M_sun. Isochrone fitting in the Hertzsprung-Russell diagram gives a turn-off age of 1.5 Myr and the median age of 1.9 Myr from the PMS members with a spread of 5 Myr. We derive the initial mass function (IMF)...

  8. Protoplanetary Disks in the Nearest Star-Forming Cloud Mid-Infrared Imaging and Optical Spectroscopy of MBM 12 Members

    CERN Document Server

    Jayawardhana, R; Barrado y Navascués, D; Telesco, C M; Hearty, T J; Jayawardhana, Ray; Wolk, Scott J.; Navascues, David Barrado y; Telesco, Charles M.; Hearty, Thomas J.

    2001-01-01

    The recent identification of several groups of young stars within 100 parsecs of the Sun has generated widespread interest. Given their proximity and possible age differences, these systems are ideally suited for detailed studies of star and planet formation. Here we report on the first investigation of protoplanetary disks in one such group, the high-latitude cloud MBM 12 at a distance of $\\sim$65 pc. We present mid-infrared observations of the eight candidate pre-main-sequence (PMS) members and the two main-sequence (MS) stars in the same line-of-sight which may or may not be associated with the group. We have also derived H$\\alpha$ and Li line widths from medium-resolution optical spectra. We report the discovery of significant mid-infrared excess from six PMS stars --LkH$\\alpha$ 262, LkH$\\alpha$ 263, LkH$\\alpha$ 264, E02553+2018, RXJ0258.3+1947 and S18 --presumably due to optically thick circumstellar disks. Our flux measurements for the other two PMS stars and the two MS stars are consistent with photosp...

  9. Yeast genome sequencing:

    DEFF Research Database (Denmark)

    Piskur, Jure; Langkjær, Rikke Breinhold

    2004-01-01

    For decades, unicellular yeasts have been general models to help understand the eukaryotic cell and also our own biology. Recently, over a dozen yeast genomes have been sequenced, providing the basis to resolve several complex biological questions. Analysis of the novel sequence data has shown...... of closely related species helps in gene annotation and to answer how many genes there really are within the genomes. Analysis of non-coding regions among closely related species has provided an example of how to determine novel gene regulatory sequences, which were previously difficult to analyse because...... they are short and degenerate and occupy different positions. Comparative genomics helps to understand the origin of yeasts and points out crucial molecular events in yeast evolutionary history, such as whole-genome duplication and horizontal gene transfer(s). In addition, the accumulating sequence data provide...

  10. Scope and Sequence.

    Science.gov (United States)

    Callison, Daniel

    2002-01-01

    Discusses scope and sequence plans for curriculum coordination in elementary and secondary education related to school libraries. Highlights include library skills; levels of learning objectives; technology skills; media literacy skills; and information inquiry skills across disciplines by grade level. (LRW)

  11. Evolution of DNA sequencing

    National Research Council Canada - National Science Library

    Tipu, Hamid Nawaz; Shabbir, Ambreen

    2015-01-01

    Sanger and coworkers introduced DNA sequencing in 1970s for the first time. It principally relied on termination of growing nucleotide chain when a dideoxythymidine triphosphate (ddTTP) was inserted...

  12. Pierre Robin sequence

    Science.gov (United States)

    Pierre Robin syndrome; Pierre Robin complex; Pierre Robin anomaly ... The exact causes of Pierre Robin sequence are unknown. It may be part of many genetic syndromes. The lower jaw develops slowly before birth, but may grow ...

  13. In Favor of Sequencing?

    NARCIS (Netherlands)

    van der Borgh, G.J.C.

    2014-01-01

    This short article is a contribution to an online discussion about political sequencing and stability. It argues that despite all the risks of democratization in fragile states,a more gradual approach should be preferred.

  14. Gomphid DNA sequence data

    Data.gov (United States)

    U.S. Environmental Protection Agency — DNA sequence data for several genetic loci. This dataset is not publicly accessible because: It's already publicly available on GenBank. It can be accessed through...

  15. Text Mining: (Asynchronous Sequences

    Directory of Open Access Journals (Sweden)

    Sheema Khan

    2014-12-01

    Full Text Available In this paper we tried to correlate text sequences those provides common topics for semantic clues. We propose a two step method for asynchronous text mining. Step one check for the common topics in the sequences and isolates these with their timestamps. Step two takes the topic and tries to give the timestamp of the text document. After multiple repetitions of step two, we could give optimum result.

  16. Malaria Genome Sequencing Project

    Science.gov (United States)

    2004-01-01

    million cases and up to 2.7 million A whole chromosome shotgun sequencing strategy was used to deaths from malaria each year. The mortality levels are...deaths from malaria each year. The mortality levels are greatest in determine the genome sequence of P. falciparum clone 3D7. This sub-Saharan Africa...aminolevulinic acid dehydratase. Cura . Genet. 40, 391-398 (2002). 15. Lasonder, E. et al Analysis of the Plasmodium falciparum proteome by high-accuracy mass

  17. Biological sequence analysis

    DEFF Research Database (Denmark)

    Durbin, Richard; Eddy, Sean; Krogh, Anders Stærmose

    This book provides an up-to-date and tutorial-level overview of sequence analysis methods, with particular emphasis on probabilistic modelling. Discussed methods include pairwise alignment, hidden Markov models, multiple alignment, profile searches, RNA secondary structure analysis, and phylogene......This book provides an up-to-date and tutorial-level overview of sequence analysis methods, with particular emphasis on probabilistic modelling. Discussed methods include pairwise alignment, hidden Markov models, multiple alignment, profile searches, RNA secondary structure analysis...

  18. Genome sequencing conference II

    Energy Technology Data Exchange (ETDEWEB)

    1990-01-01

    Genome Sequencing Conference 2 was held September 30 to October 30, 1990. 26 speaker abstracts and 33 poster presentations were included in the program report. New and improved methods for DNA sequencing and genetic mapping were presented. Many of the papers were concerned with accuracy and speed of acquisition of data with computers and automation playing an increasing role. Individual papers have been processed separately for inclusion on the database.

  19. HIV Sequence Compendium 2010

    Energy Technology Data Exchange (ETDEWEB)

    Kuiken, Carla [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Foley, Brian [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Leitner, Thomas [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Apetrei, Christian [Univ. of Pittsburgh, PA (United States); Hahn, Beatrice [Univ. of Alabama, Tuscaloosa, AL (United States); Mizrachi, Ilene [National Center for Biotechnology Information, Bethesda, MD (United States); Mullins, James [Univ. of Washington, Seattle, WA (United States); Rambaut, Andrew [Univ. of Edinburgh, Scotland (United Kingdom); Wolinsky, Steven [Northwestern Univ., Evanston, IL (United States); Korber, Bette [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2010-12-31

    This compendium is an annual printed summary of the data contained in the HIV sequence database. In these compendia we try to present a judicious selection of the data in such a way that it is of maximum utility to HIV researchers. Each of the alignments attempts to display the genetic variability within the different species, groups and subtypes of the virus. This compendium contains sequences published before January 1, 2010. Hence, though it is called the 2010 Compendium, its contents correspond to the 2009 curated alignments on our website. The number of sequences in the HIV database is still increasing exponentially. In total, at the time of printing, there were 339,306 sequences in the HIV Sequence Database, an increase of 45% since last year. The number of near complete genomes (>7000 nucleotides) increased to 2576 by end of 2009, reflecting a smaller increase than in previous years. However, as in previous years, the compendium alignments contain only a small fraction of these. Included in the alignments are a small number of sequences representing each of the subtypes and the more prevalent circulating recombinant forms (CRFs) such as 01 and 02, as well as a few outgroup sequences (group O and N and SIV-CPZ). Of the rarer CRFs we included one representative each. A more complete version of all alignments is available on our website, http://www.hiv.lanl.gov/content/sequence/NEWALIGN/align.html. Reprints are available from our website in the form of both HTML and PDF files. As always, we are open to complaints and suggestions for improvement. Inquiries and comments regarding the compendium should be addressed to seq-info@lanl.gov.

  20. Adaptive Processing for Sequence Alignment

    KAUST Repository

    Zidan, Mohammed Affan

    2012-01-26

    Disclosed are various embodiments for adaptive processing for sequence alignment. In one embodiment, among others, a method includes obtaining a query sequence and a plurality of database sequences. A first portion of the plurality of database sequences is distributed to a central processing unit (CPU) and a second portion of the plurality of database sequences is distributed to a graphical processing unit (GPU) based upon a predetermined splitting ratio associated with the plurality of database sequences, where the database sequences of the first portion are shorter than the database sequences of the second portion. A first alignment score for the query sequence is determined with the CPU based upon the first portion of the plurality of database sequences and a second alignment score for the query sequence is determined with the GPU based upon the second portion of the plurality of database sequences.

  1. Controlled processing during sequencing.

    Science.gov (United States)

    Thothathiri, Malathi; Rattinger, Michelle

    2015-01-01

    Longstanding evidence has identified a role for the frontal cortex in sequencing within both linguistic and non-linguistic domains. More recently, neuropsychological studies have suggested a specific role for the left premotor-prefrontal junction (BA 44/6) in selection between competing alternatives during sequencing. In this study, we used neuroimaging with healthy adults to confirm and extend knowledge about the neural correlates of sequencing. Participants reproduced visually presented sequences of syllables and words using manual button presses. Items in the sequence were presented either consecutively or concurrently. Concurrent presentation is known to trigger the planning of multiple responses, which might compete with one another. Therefore, we hypothesized that regions involved in controlled processing would show greater recruitment during the concurrent than the consecutive condition. Whole-brain analysis showed concurrent > consecutive activation in sensory, motor and somatosensory cortices and notably also in rostral-dorsal anterior cingulate cortex. Region of interest analyses showed increased activation within left BA 44/6 and correlation between this region's activation and behavioral response times. Functional connectivity analysis revealed increased connectivity between left BA 44/6 and the posterior lobe of the cerebellum during the concurrent than the consecutive condition. These results corroborate recent evidence and demonstrate the involvement of BA 44/6 and other control regions when ordering co-activated representations.

  2. Controlled processing during sequencing

    Directory of Open Access Journals (Sweden)

    Malathi eThothathiri

    2015-10-01

    Full Text Available Longstanding evidence has identified a role for the frontal cortex in sequencing within both linguistic and non-linguistic domains. More recently, neuropsychological studies have suggested a specific role for the left premotor-prefrontal junction (BA 44/6 in selection between competing alternatives during sequencing. In this study, we used neuroimaging with healthy adults to confirm and extend knowledge about the neural correlates of sequencing. Participants reproduced visually presented sequences of syllables and words using manual button presses. Items in the sequence were presented either consecutively or concurrently. Concurrent presentation is known to trigger the planning of multiple responses, which might compete with one another. Therefore, we hypothesized that regions involved in controlled processing would show greater recruitment during the concurrent than the consecutive condition. Whole-brain analysis showed concurrent > consecutive activation in sensory, motor and somatosensory cortices and notably also in rostral-dorsal anterior cingulate cortex (ACC. Region of interest analyses showed increased activation within left BA 44/6 and correlation between this region’s activation and behavioral response times. Functional connectivity analysis revealed increased connectivity between left BA 44/6 and the posterior lobe of the cerebellum during the concurrent than the consecutive condition. These results corroborate recent evidence and demonstrate the involvement of BA 44/6 and other control regions when ordering co-activated representations.

  3. Program Synthesizes UML Sequence Diagrams

    Science.gov (United States)

    Barry, Matthew R.; Osborne, Richard N.

    2006-01-01

    A computer program called "Rational Sequence" generates Universal Modeling Language (UML) sequence diagrams of a target Java program running on a Java virtual machine (JVM). Rational Sequence thereby performs a reverse engineering function that aids in the design documentation of the target Java program. Whereas previously, the construction of sequence diagrams was a tedious manual process, Rational Sequence generates UML sequence diagrams automatically from the running Java code.

  4. Sequencing BPS Spectra

    CERN Document Server

    Gukov, Sergei; Saberi, Ingmar; Stosic, Marko; Sulkowski, Piotr

    2015-01-01

    This paper provides both a detailed study of color-dependence of link homologies, as realized in physics as certain spaces of BPS states, and a broad study of the behavior of BPS states in general. We consider how the spectrum of BPS states varies as continuous parameters of a theory are perturbed. This question can be posed in a wide variety of physical contexts, and we answer it by proposing that the relationship between unperturbed and perturbed BPS spectra is described by a spectral sequence. These general considerations unify previous applications of spectral sequence techniques to physics, and explain from a physical standpoint the appearance of many spectral sequences relating various link homology theories to one another. We also study structural properties of colored HOMFLY homology for links and evaluate Poincar\\'e polynomials in numerous examples. Among these structural properties is a novel "sliding" property, which can be explained by using (refined) modular $S$-matrix. This leads to the identifi...

  5. Next-generation sequencing

    DEFF Research Database (Denmark)

    Rieneck, Klaus; Bak, Mads; Jønson, Lars

    2013-01-01

    information obtained allows well for statistical analysis of the data. This general approach can be integrated into current laboratory practice and has numerous applications. Besides DNA-based predictions of blood group phenotypes, platelet phenotypes, or sickle cell anemia, and the determination of zygosity......, Illumina); several millions of PCR sequences were analyzed. RESULTS: The results demonstrated the feasibility of diagnosing the fetal KEL1 or KEL2 blood group from cell-free DNA purified from maternal plasma. CONCLUSION: This method requires only one primer pair, and the large amount of sequence...

  6. Family Sequencing and Cooperation

    NARCIS (Netherlands)

    Grundel, S.; Ciftci, B.B.; Borm, P.E.M.; Hamers, H.J.M.

    2012-01-01

    To analyze the allocation problem of the maximal cost savings of the whole group of jobs, we define and analyze a so-called corresponding cooperative family sequencing game which explicitly takes into account the maximal cost savings for any coalition of jobs. Using nonstandard techniques we prove t

  7. Twin anemia polycythemia sequence

    NARCIS (Netherlands)

    Slaghekke, Femke

    2014-01-01

    In this thesis we describe that Twin Anemia Polycythemia Sequence (TAPS) is a form of chronic feto-fetal transfusion in monochorionic (identical) twins based on a small amount of blood transfusion through very small anastomoses. For the antenatal diagnosis of TAPS, Middle Cerebral Artery – Peak Syst

  8. Twin anemia polycythemia sequence

    NARCIS (Netherlands)

    Slaghekke, Femke

    2014-01-01

    In this thesis we describe that Twin Anemia Polycythemia Sequence (TAPS) is a form of chronic feto-fetal transfusion in monochorionic (identical) twins based on a small amount of blood transfusion through very small anastomoses. For the antenatal diagnosis of TAPS, Middle Cerebral Artery – Peak

  9. Biological sequence analysis

    DEFF Research Database (Denmark)

    Durbin, Richard; Eddy, Sean; Krogh, Anders Stærmose

    This book provides an up-to-date and tutorial-level overview of sequence analysis methods, with particular emphasis on probabilistic modelling. Discussed methods include pairwise alignment, hidden Markov models, multiple alignment, profile searches, RNA secondary structure analysis, and phylogene...

  10. Chandra X-Ray Observations of Young Clusters. III. NGC 2264 and the Orion Flanking Fields

    CERN Document Server

    Rebull, L M; Micela, G; Ramírez, S V; Sciortino, S; Stauffer, J R; Strom, S E; Wolff, S C

    2006-01-01

    Chandra observations of solar-like pre-main sequence (PMS) stars in the Orion Flanking Fields (age ~1 Myr) and NGC 2264 (~3 Myr) are compared with the results of the COUP survey of similar objects in the ONC (~0.5 Myr). The correlations between log Lx and mass found for PMS stars on convective tracks in these clusters are consistent with the relationships found for the ONC, indicating little change in the median values of either log Lx or log Lx/Lbol during the first ~3-5 Myr of evolution down convective tracks. The fraction of stars with extreme values of Lx, more than 10 times higher than the average for a given Lbol or with log Lx/Lbol greater than the canonical saturation value of -2.9, is however larger by a factor of two in the younger ONC when compared with the Orion FF and NGC 2264. PMS stars in NGC 2264 on radiative tracks have Lx/Lbol values that are systematically lower by a factor of ~10 times than those found for stars of similar mass on convective tracks. The dramatic decrease in flux from conve...

  11. Radio and infrared properties of young stars

    Science.gov (United States)

    Panagia, Nino

    1987-01-01

    Observing young stars, or more appropriately, pre-main-sequence (PMS) stars, in the infrared and at radio frequencies has the advantage over optical observation in that the heavy extinction associated with a star forming region is only a minor problem, so that the whole region can be studied thoroughly. Therefore, it means being able to: (1) search for stars and do statistical studies on the rate of star formation; (2) determine their luminosity, hence, to study luminosity functions and initial mass functions down to low masses; and (3) to study their spectra and, thus, to determine the prevailing conditions at and near the surface of a newly born star and its relations with the surrounding environment. The third point is of principal interest. The report limits itself to a consideration of the observations concerning the processes of outflows from, and accretion onto, PMS stars and the theory necessary to interpret them. Section 2 discusses the radiative processes relevant in stellar outflows. The main observational results are presented in Section 3. A discussion of the statistical properties of stellar winds from PMS stars are given in Section 4.

  12. VizieR Online Data Catalog: ISOCAM observations in Cha I. (Persi+, 2000)

    Science.gov (United States)

    Persi, P.; Marenzi, A. M.; Olofsson, G.; Kaas, A. A.; Nordh, L.; Huldtgren, M.; Abergel, A.; Andre, Philippe M.; Bontemps, S.; Boulanger, F.; Burgdorf, M.; Casali, M. M.; Cesarsky, C.; Copet, E.; Davies, J. I.; Falgarone, E.; Montmerle, T.; Perault, M.; Prusti, T.; Puget, J. L.; Sibille, F.

    2000-03-01

    We present the results of an ISOCAM survey of the Chamaeleon I dark cloud conducted in two broad-band filters at 6.7 and 14.3μm. In an area of 0.59deg2. we have detected a total of 282 mid-IR sources with 103 sources observed in both filters. Combining the ISOCAM observations with the I, J, and Ks data obtained with DENIS, we have found 108 pre-main-sequence (PMS) stars in the region, of which 34 were previously unidentified. Several of these newly discovered young stellar objects are relatively faint suggesting a population in Cha I of very low mass objects that probably includes brown dwarfs in their early contraction phases. Finally, most of the PMS stars show the spectral index computed between 2.2 and 14.3μm typical of Class II sources. The luminosity function (LF) derived for our detected PMS stars is discussed. (5 data files).

  13. ISOCAM observations of the Chamaeleon I dark cloud

    Science.gov (United States)

    Persi, P.; Marenzi, A. R.; Olofsson, G.; Kaas, A. A.; Nordh, L.; Huldtgren, M.; Abergel, A.; André, P.; Bontemps, S.; Boulanger, F.; Burggdorf, M.; Casali, M. M.; Cesarsky, C. J.; Copet, E.; Davies, J.; Falgarone, E.; Montmerle, T.; Perault, M.; Prusti, T.; Puget, J. L.; Sibille, F.

    2000-05-01

    We present the results of an ISOCAM survey of the Chamaeleon I dark cloud conducted in two broad-band filters at 6.7 and 14.3 mu m. In an area of 0.59 sq.deg. we have detected a total of 282 mid-IR sources with 103 sources observed in both filters. Combining the ISOCAM observations with the I, J, and K_s data obtained with DENIS, we have found 108 pre-main-sequence (PMS) stars in the region, of which 34 were previously unidentified. Several of these newly discovered young stellar objects are relatively faint suggesting a population in Cha I of very low mass objects that probably includes brown dwarfs in their early contraction phases. Finally, most of the PMS stars show the spectral index computed between 2.2 and 14.3 mu m typical of Class II sources. The luminosity function (LF) derived for our detected PMS stars is discussed. ISO is an ESA project with instruments funded by ESA Member States (especially the PI countries: France, Germany, the Netherlands and the United Kingdom) and with the participation of ISAS and NASA. Tables 1 and 2 are only available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsweb.u-strasbg.fr/Abstract.html Tables 3 and 4 are only available with the on-line publication at http://link.springer.de/link/service/journals/00230/

  14. Allele Re-sequencing Technologies

    DEFF Research Database (Denmark)

    Byrne, Stephen; Farrell, Jacqueline Danielle; Asp, Torben

    2013-01-01

    The development of next-generation sequencing technologies has made sequencing an affordable approach for detection of genetic variations associated with various traits. However, the cost of whole genome re-sequencing still remains too high to be feasible for many plant species with large...... alternative to whole genome re-sequencing to identify causative genetic variations in plants. One challenge, however, will be efficient bioinformatics strategies for data handling and analysis from the increasing amount of sequence information....

  15. Rapid-Sequence Intubation

    Directory of Open Access Journals (Sweden)

    Evangelina Dávila Cabo de Villa

    2015-09-01

    Full Text Available In medical practice there are several situations that require immediate intervention of the airway in some patients, in order to ensure proper entrance and exit of gases into and out of the lungs and prevent aspiration. Rapid-sequence intubation has been considered as the administration of a hypnotic agent and a neuromuscular relaxant consecutively (virtually simultaneously to facilitate orotracheal intubation in critically ill patients and minimize the risk of aspiration. This paper aims to collect elements that promote a successful medical management according to the situation presented, since there is no single way of proceeding in case of rapid-sequence intubation. The elements to consider include: knowing the anatomy of the upper respiratory tract, having a group of drugs to choose from, receiving adequate training and having an alternative plan for the difficulties that may arise.

  16. Sequence Classification: 885394 [

    Lifescience Database Archive (English)

    Full Text Available 703); The expression pattern of this gene is described in PMID:12000842; possible frameshift detected when compared...Non-TMB TMH Non-TMB Non-TMB Non-TMB Non-TMB >gi|23619146|ref|NP_705108.1| Slight di...fference exist when compared to the published sequence of EBL-1 from Dd2 strain of P. falciparum (PMID:10613

  17. Sequencing of aromatase inhibitors

    OpenAIRE

    2005-01-01

    Since the development of the third-generation aromatase inhibitors (AIs), anastrozole, letrozole and exemestane, these agents have been the subject of intensive research to determine their optimal use in advanced breast cancer. Not only have they replaced progestins in second-line therapy and challenged the role of tamoxifen in first-line, but there is also evidence for a lack of cross-resistance between the steroidal and nonsteroidal AIs, meaning that they may be used in sequence to obtain p...

  18. Properties of Semijoin Sequences

    Institute of Scientific and Technical Information of China (English)

    BengC.Ooi; B.Srinivasan

    1989-01-01

    The problem of finding optimum semijoin sequ4ence of an arbitrary query under linear cost function for the transmission cost is NP.hard.Hence heuristic algorithms with desirable properties are explored.In this paper four properties of semijoin programs for distributed query processing are identified,The use of these properties in constructing semijoin sequence is justified.An existing algorithm is modified incorporating these properties.Empirical comparison with existing algorithms shows the superiority of the proposed algorithm.

  19. Learning Sequence Neighbourhood Metrics

    CERN Document Server

    Bayer, Justin; van der Smagt, Patrick

    2011-01-01

    Recurrent neural networks (RNNs) in combination with a pooling operator and the neighbourhood components analysis (NCA) objective function are able to detect the characterizing dynamics of sequences and embed them into a fixed-length vector space of arbitrary dimensionality. Subsequently, the resulting features are meaningful and can be used for visualization or nearest neighbour classification in linear time. This kind of metric learning for sequential data enables the use of algorithms tailored towards fixed length vector spaces such as R^n.

  20. Sequencing BPS spectra

    Science.gov (United States)

    Gukov, Sergei; Nawata, Satoshi; Saberi, Ingmar; Stošić, Marko; Sułkowski, Piotr

    2016-03-01

    This paper provides both a detailed study of color-dependence of link homologies, as realized in physics as certain spaces of BPS states, and a broad study of the behavior of BPS states in general. We consider how the spectrum of BPS states varies as continuous parameters of a theory are perturbed. This question can be posed in a wide variety of physical contexts, and we answer it by proposing that the relationship between unperturbed and perturbed BPS spectra is described by a spectral sequence. These general considerations unify previous applications of spectral sequence techniques to physics, and explain from a physical standpoint the appearance of many spectral sequences relating various link homology theories to one another. We also study structural properties of colored HOMFLY homology for links and evaluate Poincaré polynomials in numerous examples. Among these structural properties is a novel "sliding" property, which can be explained by using (refined) modular S-matrix. This leads to the identification of modular transformations in Chern-Simons theory and 3d {N}=2 theory via the 3d/3d correspondence. Lastly, we introduce the notion of associated varieties as classical limits of recursion relations of colored superpolynomials of links, and study their properties.

  1. Image sequence analysis

    CERN Document Server

    1981-01-01

    The processing of image sequences has a broad spectrum of important applica­ tions including target tracking, robot navigation, bandwidth compression of TV conferencing video signals, studying the motion of biological cells using microcinematography, cloud tracking, and highway traffic monitoring. Image sequence processing involves a large amount of data. However, because of the progress in computer, LSI, and VLSI technologies, we have now reached a stage when many useful processing tasks can be done in a reasonable amount of time. As a result, research and development activities in image sequence analysis have recently been growing at a rapid pace. An IEEE Computer Society Workshop on Computer Analysis of Time-Varying Imagery was held in Philadelphia, April 5-6, 1979. A related special issue of the IEEE Transactions on Pattern Anal­ ysis and Machine Intelligence was published in November 1980. The IEEE Com­ puter magazine has also published a special issue on the subject in 1981. The purpose of this book ...

  2. The Galaxy End Sequence

    Science.gov (United States)

    Eales, Stephen; de Vis, Pieter; Smith, Matthew W. L.; Appah, Kiran; Ciesla, Laure; Duffield, Chris; Schofield, Simon

    2017-03-01

    A common assumption is that galaxies fall in two distinct regions of a plot of specific star formation rate (SSFR) versus galaxy stellar mass: a star-forming galaxy main sequence (GMS) and a separate region of 'passive' or 'red and dead galaxies'. Starting from a volume-limited sample of nearby galaxies designed to contain most of the stellar mass in this volume, and thus representing the end-point of ≃12 billion years of galaxy evolution, we investigate the distribution of galaxies in this diagram today. We show that galaxies follow a strongly curved extended GMS with a steep negative slope at high galaxy stellar masses. There is a gradual change in the morphologies of the galaxies along this distribution, but there is no clear break between early-type and late-type galaxies. Examining the other evidence that there are two distinct populations, we argue that the 'red sequence' is the result of the colours of galaxies changing very little below a critical value of the SSFR, rather than implying a distinct population of galaxies. Herschel observations, which show at least half of early-type galaxies contain a cool interstellar medium, also imply continuity between early-type and late-type galaxies. This picture of a unitary population of galaxies requires more gradual evolutionary processes than the rapid quenching process needed to explain two distinct populations. We challenge theorists to predict quantitatively the properties of this 'Galaxy End Sequence'.

  3. Sequencing BPS spectra

    Energy Technology Data Exchange (ETDEWEB)

    Gukov, Sergei [Walter Burke Institute for Theoretical Physics, California Institute of Technology,1200 E California Blvd, Pasadena, CA 91125 (United States); Max-Planck-Institut für Mathematik,Vivatsgasse 7, D-53111 Bonn (Germany); Nawata, Satoshi [Walter Burke Institute for Theoretical Physics, California Institute of Technology,1200 E California Blvd, Pasadena, CA 91125 (United States); Centre for Quantum Geometry of Moduli Spaces, University of Aarhus,Nordre Ringgade 1, DK-8000 (Denmark); Saberi, Ingmar [Walter Burke Institute for Theoretical Physics, California Institute of Technology,1200 E California Blvd, Pasadena, CA 91125 (United States); Stošić, Marko [CAMGSD, Departamento de Matemática, Instituto Superior Técnico,Av. Rovisco Pais, 1049-001 Lisbon (Portugal); Mathematical Institute SANU,Knez Mihajlova 36, 11000 Belgrade (Serbia); Sułkowski, Piotr [Walter Burke Institute for Theoretical Physics, California Institute of Technology,1200 E California Blvd, Pasadena, CA 91125 (United States); Faculty of Physics, University of Warsaw,ul. Pasteura 5, 02-093 Warsaw (Poland)

    2016-03-02

    This paper provides both a detailed study of color-dependence of link homologies, as realized in physics as certain spaces of BPS states, and a broad study of the behavior of BPS states in general. We consider how the spectrum of BPS states varies as continuous parameters of a theory are perturbed. This question can be posed in a wide variety of physical contexts, and we answer it by proposing that the relationship between unperturbed and perturbed BPS spectra is described by a spectral sequence. These general considerations unify previous applications of spectral sequence techniques to physics, and explain from a physical standpoint the appearance of many spectral sequences relating various link homology theories to one another. We also study structural properties of colored HOMFLY homology for links and evaluate Poincaré polynomials in numerous examples. Among these structural properties is a novel “sliding” property, which can be explained by using (refined) modular S-matrix. This leads to the identification of modular transformations in Chern-Simons theory and 3d N=2 theory via the 3d/3d correspondence. Lastly, we introduce the notion of associated varieties as classical limits of recursion relations of colored superpolynomials of links, and study their properties.

  4. Evolution of lithium abundance in the Sun and solar twins

    Science.gov (United States)

    Thévenin, F.; Oreshina, A. V.; Baturin, V. A.; Gorshkov, A. B.; Morel, P.; Provost, J.

    2017-02-01

    Evolution of the 7Li abundance in the convection zone of the Sun during different stages of its life time is considered to explain its low photospheric value in comparison with that of the solar system meteorites. Lithium is intensively and transiently burned in the early stages of evolution (pre-main sequence, pMS) when the radiative core arises, and then the Li abundance only slowly decreases during the main sequence (MS). We study the rates of lithium burning during these two stages. In a model of the Sun, computed ignoring pMS and without extra-convective mixing (overshooting) at the base of the convection zone, the lithium abundance does not decrease significantly during the MS life time of 4.6 Gyr. Analysis of helioseismic inversions together with post-model computations of chemical composition indicates the presence of the overshooting region and restricts its thickness. It is estimated to be approximately half of the local pressure scale height (0.5HP) which corresponds to 3.8% of the solar radius. Introducing this extra region does not noticeably deplete lithium during the MS stage. In contrast, at the pMS stage, an overshooting region with a value of approximately 0.18HP is enough to produce the observed lithium depletion. If we conclude that the dominant lithium burning takes place during the pMS stage, the dispersion of the lithium abundance in solar twins is explained by different physical conditions, primarily during the early stage of evolution before the MS.

  5. Information Theory of DNA Sequencing

    CERN Document Server

    Motahari, Abolfazl; Tse, David

    2012-01-01

    DNA sequencing is the basic workhorse of modern day biology and medicine. Shotgun sequencing is the dominant technique used: many randomly located short fragments called reads are extracted from the DNA sequence, and these reads are assembled to reconstruct the original sequence. By drawing an analogy between the DNA sequencing problem and the classic communication problem, we define an information theoretic notion of sequencing capacity. This is the maximum number of DNA base pairs that can be resolved reliably per read, and provides a fundamental limit to the performance that can be achieved by any assembly algorithm. We compute the sequencing capacity explicitly for a simple statistical model of the DNA sequence and the read process. Using this framework, we also study the impact of noise in the read process on the sequencing capacity.

  6. A vision for ubiquitous sequencing.

    Science.gov (United States)

    Erlich, Yaniv

    2015-10-01

    Genomics has recently celebrated reaching the $1000 genome milestone, making affordable DNA sequencing a reality. With this goal successfully completed, the next goal of the sequencing revolution can be sequencing sensors--miniaturized sequencing devices that are manufactured for real-time applications and deployed in large quantities at low costs. The first part of this manuscript envisions applications that will benefit from moving the sequencers to the samples in a range of domains. In the second part, the manuscript outlines the critical barriers that need to be addressed in order to reach the goal of ubiquitous sequencing sensors.

  7. Psychoacoustic Properties of Fibonacci Sequences

    Directory of Open Access Journals (Sweden)

    J. Sokoll

    2008-01-01

    Full Text Available 1202, Fibonacci set up one of the most interesting sequences in number theory. This sequence can be represented by so-called Fibonacci Numbers, and by a binary sequence of zeros and ones. If such a binary Fibonacci Sequence is played back as an audio file, a very dissonant sound results. This is caused by the “almost-periodic”, “self-similar” property of the binary sequence. The ratio of zeros and ones converges to the golden ratio, as do the primary and secondary spectral components intheir frequencies and amplitudes. These Fibonacci Sequences will be characterized using listening tests and psychoacoustic analyses. 

  8. Impact of insulin-treated diabetes and hemodialysis on long-term clinical outcomes following sirolimus-eluting stent deployment. Insights from a sub-study of the Cypher Stent Japan Post-Marketing Surveillance(Cypher J-PMS) Registry.

    Science.gov (United States)

    Nakamura, Masato; Yokoi, Hiroyoshi; Hamazaki, Yuji; Watarai, Masato; Kijima, Mikihiro; Mitsudo, Kazuaki

    2010-11-01

    Long-term clinical outcomes of diabetes mellitus (DM) patients who underwent drug-eluting stent deployment has not well investigated. A total of 2,050 cases were enrolled consecutively from 50 sites in Japan into the Cypher stent Japan Post-Marketing Surveillance (Cypher J-PMS) registry, and the 3-year outcomes of DM patients were analyzed. Subjects were divided into 2 groups based on the treatment of DM (insulin-treated diabetes (IT) group, n=207; and non insulin-treated diabetes (NIT) group, n=682). Major adverse cardiac event (MACE) rates in the IT group and the NIT group were 26.0% and 14.5% at 3 years, respectively (PMultivariate analysis suggested that hemodialysis and insulin-treated DM were independent predictors for MACE, and insulin-treated DM, hemodialysis and long lesions were strong independent predictors for target-lesion revascularization (TLR). Hemodialysis and insulin-treated DM were strong independent predictors of mortality and TLR in DM patients. These results might suggest that special attention to patients with hemodialysis and insulin-treated DM is warranted in the setting of sirolimus-eluting stent deployment for DM patients.

  9. Infinite sequences and series

    CERN Document Server

    Knopp, Konrad

    1956-01-01

    One of the finest expositors in the field of modern mathematics, Dr. Konrad Knopp here concentrates on a topic that is of particular interest to 20th-century mathematicians and students. He develops the theory of infinite sequences and series from its beginnings to a point where the reader will be in a position to investigate more advanced stages on his own. The foundations of the theory are therefore presented with special care, while the developmental aspects are limited by the scope and purpose of the book. All definitions are clearly stated; all theorems are proved with enough detail to ma

  10. Next-Generation Sequencing Platforms

    Science.gov (United States)

    Mardis, Elaine R.

    2013-06-01

    Automated DNA sequencing instruments embody an elegant interplay among chemistry, engineering, software, and molecular biology and have built upon Sanger's founding discovery of dideoxynucleotide sequencing to perform once-unfathomable tasks. Combined with innovative physical mapping approaches that helped to establish long-range relationships between cloned stretches of genomic DNA, fluorescent DNA sequencers produced reference genome sequences for model organisms and for the reference human genome. New types of sequencing instruments that permit amazing acceleration of data-collection rates for DNA sequencing have been developed. The ability to generate genome-scale data sets is now transforming the nature of biological inquiry. Here, I provide an historical perspective of the field, focusing on the fundamental developments that predated the advent of next-generation sequencing instruments and providing information about how these instruments work, their application to biological research, and the newest types of sequencers that can extract data from single DNA molecules.

  11. Spaces of Ideal Convergent Sequences

    Directory of Open Access Journals (Sweden)

    M. Mursaleen

    2014-01-01

    Full Text Available In the present paper, we introduce some sequence spaces using ideal convergence and Musielak-Orlicz function ℳ=Mk. We also examine some topological properties of the resulting sequence spaces.

  12. Sequence Handling by Sequence Analysis Toolbox v1.0

    DEFF Research Database (Denmark)

    Ingrell, Christian Ravnsborg; Matthiesen, Rune; Jensen, Ole Nørregaard

    2006-01-01

    The fact that mass spectrometry have become a high-throughput method calls for bioinformatic tools for automated sequence handling and prediction. For efficient use of bioinformatic tools, it is important that these tools are integrated or interfaced with each other. The purpose of sequence...... analysis toolbox v1.0 was to have a general purpose sequence analyzing tool that can import sequences obtained by high-throughput sequencing methods. The program includes algorithms for calculation or prediction of isoelectric point, hydropathicity index, transmembrane segments, and glycosylphosphatidyl...

  13. The Galaxy End Sequence

    CERN Document Server

    Eales, Stephen; Smith, Matthew; Appah, Kiran; Ciesla, Laure; Duffield, Chris; Schofield, Simon

    2016-01-01

    A common assumption is that galaxies fall in two distinct regions on a plot of specific star-formation rate (SSFR) versus galaxy stellar mass: a star-forming Galaxy Main Sequence (GMS) and a separate region of `passive' or `red and dead galaxies'. Starting from a volume-limited sample of nearby galaxies designed to contain most of the stellar mass in this volume, and thus being a fair representation of the Universe at the end of 12 billion years of galaxy evolution, we investigate the distribution of galaxies in this diagram today. We show that galaxies follow a strongly curved extended GMS with a steep negative slope at high galaxy stellar masses. There is a gradual change in the morphologies of the galaxies along this distribution, but there is no clear break between early-type and late-type galaxies. Examining the other evidence that there are two distinct populations, we argue that the `red sequence' is the result of the colours of galaxies changing very little below a critical value of the SSFR, rather t...

  14. Rapid Polymer Sequencer

    Science.gov (United States)

    Stolc, Viktor (Inventor); Brock, Matthew W (Inventor)

    2013-01-01

    Method and system for rapid and accurate determination of each of a sequence of unknown polymer components, such as nucleic acid components. A self-assembling monolayer of a selected substance is optionally provided on an interior surface of a pipette tip, and the interior surface is immersed in a selected liquid. A selected electrical field is impressed in a longitudinal direction, or in a transverse direction, in the tip region, a polymer sequence is passed through the tip region, and a change in an electrical current signal is measured as each polymer component passes through the tip region. Each of the measured changes in electrical current signals is compared with a database of reference electrical change signals, with each reference signal corresponding to an identified polymer component, to identify the unknown polymer component with a reference polymer component. The nanopore preferably has a pore inner diameter of no more than about 40 nm and is prepared by heating and pulling a very small section of a glass tubing.

  15. Novel sequences propel familiar folds.

    Science.gov (United States)

    Jawad, Zahra; Paoli, Massimo

    2002-04-01

    Recent structure determinations have made new additions to a set of strikingly different sequences that give rise to the same topology. Proteins with a beta propeller fold are characterized by extreme sequence diversity despite the similarity in their three-dimensional structures. Several fold predictions, based in part on sequence repeats thought to match modular beta sheets, have been proved correct.

  16. Dissecting 30 Doradus: Optical and Near Infrared Star Formation History of the starburst cluster NGC2070 from the Hubble Tarantula Treasury Project

    Science.gov (United States)

    Cignoni, Michele

    2015-08-01

    I will present new results on the star formation history of 30 Doradus in the Large Magellanic Cloud based on the panchromatic imaging survey Hubble Tarantula Treasury Project (HTTP). Here the focus is on the starburst cluster NGC2070. The star formation history is derived by comparing the deepest ever optical and NIR color-magnitude diagrams (CMDs) with state-of-the-art synthetic CMDs generated with the latest PARSEC models, which include all stellar phases from pre-main sequence (PMS) to post-main sequence. For the first time in this region we are able to measure the star formation using intermediate and low mass stars simultaneously. Our results suggest that NGC2070 experienced a prolonged activity. I will discuss the detailed star formation history, initial mass function and reddening distribution and how these relate to previous studies of this starburst region.

  17. Multilocus Sequence Typing of Total-Genome-Sequenced Bacteria

    DEFF Research Database (Denmark)

    Larsen, Mette Voldby; Cosentino, Salvatore; Rasmussen, Simon

    2012-01-01

    Accurate strain identification is essential for anyone working with bacteria. For many species, multilocus sequence typing (MLST) is considered the "gold standard" of typing, but it is traditionally performed in an expensive and time-consuming manner. As the costs of whole-genome sequencing (WGS...... the MLST databases are downloaded monthly, and the best-matching MLST alleles of the specified MLST scheme are found using a BLAST-based ranking method. The sequence type is then determined by the combination of alleles identified. The method was tested on preassembled genomes from 336 isolates covering 56...... MLST schemes, on short sequence reads from 387 isolates covering 10 schemes, and on a small test set of short sequence reads from 29 isolates for which the sequence type had been determined by traditional methods. The method presented here enables investigators to determine the sequence types...

  18. Hubble Tarantula Treasury Project V. The star cluster Hodge 301: the old face of 30 Doradus

    CERN Document Server

    Cignoni, M; van der Marel, R P; Lennon, D J; Tosi, M; Grebel, E K; Gallagher, J S; Aloisi, A; de Marchi, G; Gouliermis, D A; Larsen, S; Panagia, N; Smith, L J

    2016-01-01

    Based on color-magnitude diagrams (CMDs) from the Hubble Space Telescope Hubble Tarantula Treasury Project (HTTP) survey, we present the star formation history (SFH) of Hodge~301, the oldest star cluster in the Tarantula Nebula. The HTTP photometry extends faint enough to reach, for the first time, the cluster pre-main sequence (PMS) turn-on, where the PMS joins the main sequence. Using the location of this feature, along with synthetic CMDs generated with the latest PARSEC models, we find that Hodge~301 is older than previously thought, with an age between 26.5 and 31.5 Myr. From this age, we also estimate that between 38 and 61 supernovae Type-II exploded in the region. The same age is derived from the main sequence turn-off, whereas the age derived from the post-main sequence stars is younger and between 20 and 25 Myr. Other relevant parameters are a total stellar mass of $\\approx 8800\\,\\pm 800$M$_{\\odot}$ and average reddening E(B$-$V) $\\approx 0.22-0.24$ mag, with a differential reddening $\\delta$E(B$-$V...

  19. Hubble Tarantula Treasury Project V. The Star Cluster Hodge 301: The Old Face of 30 Doradus

    Science.gov (United States)

    Cignoni, M.; Sabbi, E.; van der Marel, R. P.; Lennon, D. J.; Tosi, M.; Grebel, E. K.; Gallagher, J. S., III; Aloisi, A.; de Marchi, G.; Gouliermis, D. A.; Larsen, S.; Panagia, N.; Smith, L. J.

    2016-12-01

    Based on color-magnitude diagrams (CMDs) from the Hubble Space Telescope Hubble Tarantula Treasury Project (HTTP) survey, we present the star formation history of Hodge 301, the oldest star cluster in the Tarantula Nebula. The HTTP photometry extends faint enough to reach, for the first time, the cluster pre-main sequence (PMS) turn-on, where the PMS joins the main sequence. Using the location of this feature, along with synthetic CMDs generated with the latest PARSEC models, we find that Hodge 301 is older than previously thought, with an age between 26.5 and 31.5 Myr. From this age, we also estimate that between 38 and 61 Type II supernovae exploded in the region. The same age is derived from the main sequence turn-off, whereas the age derived from the post-main sequence stars is younger and between 20 and 25 Myr. Other relevant parameters are a total stellar mass of ≈8800 ± 800 M ⊙ and average reddening E(B - V) ≈ 0.22-0.24 mag, with a differential reddening δE(B - V) ≈ 0.04 mag. Based on observations with the NASA/ESA Hubble Space Telescope, obtained at the Space Telescope Science Institute, which is operated by AURA Inc., under NASA contract NAS 5-26555.

  20. RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

    Science.gov (United States)

    Shibata, Kazuhiro; Itoh, Masayoshi; Aizawa, Katsunori; Nagaoka, Sumiharu; Sasaki, Nobuya; Carninci, Piero; Konno, Hideaki; Akiyama, Junichi; Nishi, Katsuo; Kitsunai, Tokuji; Tashiro, Hideo; Itoh, Mari; Sumi, Noriko; Ishii, Yoshiyuki; Nakamura, Shin; Hazama, Makoto; Nishine, Tsutomu; Harada, Akira; Yamamoto, Rintaro; Matsumoto, Hiroyuki; Sakaguchi, Sumito; Ikegami, Takashi; Kashiwagi, Katsuya; Fujiwake, Syuji; Inoue, Kouji; Togawa, Yoshiyuki; Izawa, Masaki; Ohara, Eiji; Watahiki, Masanori; Yoneda, Yuko; Ishikawa, Tomokazu; Ozawa, Kaori; Tanaka, Takumi; Matsuura, Shuji; Kawai, Jun; Okazaki, Yasushi; Muramatsu, Masami; Inoue, Yorinao; Kira, Akira; Hayashizaki, Yoshihide

    2000-01-01

    The RIKEN high-throughput 384-format sequencing pipeline (RISA system) including a 384-multicapillary sequencer (the so-called RISA sequencer) was developed for the RIKEN mouse encyclopedia project. The RISA system consists of colony picking, template preparation, sequencing reaction, and the sequencing process. A novel high-throughput 384-format capillary sequencer system (RISA sequencer system) was developed for the sequencing process. This system consists of a 384-multicapillary auto sequencer (RISA sequencer), a 384-multicapillary array assembler (CAS), and a 384-multicapillary casting device. The RISA sequencer can simultaneously analyze 384 independent sequencing products. The optical system is a scanning system chosen after careful comparison with an image detection system for the simultaneous detection of the 384-capillary array. This scanning system can be used with any fluorescent-labeled sequencing reaction (chain termination reaction), including transcriptional sequencing based on RNA polymerase, which was originally developed by us, and cycle sequencing based on thermostable DNA polymerase. For long-read sequencing, 380 out of 384 sequences (99.2%) were successfully analyzed and the average read length, with more than 99% accuracy, was 654.4 bp. A single RISA sequencer can analyze 216 kb with >99% accuracy in 2.7 h (90 kb/h). For short-read sequencing to cluster the 3′ end and 5′ end sequencing by reading 350 bp, 384 samples can be analyzed in 1.5 h. We have also developed a RISA inoculator, RISA filtrator and densitometer, RISA plasmid preparator which can handle throughput of 40,000 samples in 17.5 h, and a high-throughput RISA thermal cycler which has four 384-well sites. The combination of these technologies allowed us to construct the RISA system consisting of 16 RISA sequencers, which can process 50,000 DNA samples per day. One haploid genome shotgun sequence of a higher organism, such as human, mouse, rat, domestic animals, and plants, can

  1. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

    Science.gov (United States)

    Shibata, K; Itoh, M; Aizawa, K; Nagaoka, S; Sasaki, N; Carninci, P; Konno, H; Akiyama, J; Nishi, K; Kitsunai, T; Tashiro, H; Itoh, M; Sumi, N; Ishii, Y; Nakamura, S; Hazama, M; Nishine, T; Harada, A; Yamamoto, R; Matsumoto, H; Sakaguchi, S; Ikegami, T; Kashiwagi, K; Fujiwake, S; Inoue, K; Togawa, Y

    2000-11-01

    The RIKEN high-throughput 384-format sequencing pipeline (RISA system) including a 384-multicapillary sequencer (the so-called RISA sequencer) was developed for the RIKEN mouse encyclopedia project. The RISA system consists of colony picking, template preparation, sequencing reaction, and the sequencing process. A novel high-throughput 384-format capillary sequencer system (RISA sequencer system) was developed for the sequencing process. This system consists of a 384-multicapillary auto sequencer (RISA sequencer), a 384-multicapillary array assembler (CAS), and a 384-multicapillary casting device. The RISA sequencer can simultaneously analyze 384 independent sequencing products. The optical system is a scanning system chosen after careful comparison with an image detection system for the simultaneous detection of the 384-capillary array. This scanning system can be used with any fluorescent-labeled sequencing reaction (chain termination reaction), including transcriptional sequencing based on RNA polymerase, which was originally developed by us, and cycle sequencing based on thermostable DNA polymerase. For long-read sequencing, 380 out of 384 sequences (99.2%) were successfully analyzed and the average read length, with more than 99% accuracy, was 654.4 bp. A single RISA sequencer can analyze 216 kb with >99% accuracy in 2.7 h (90 kb/h). For short-read sequencing to cluster the 3' end and 5' end sequencing by reading 350 bp, 384 samples can be analyzed in 1.5 h. We have also developed a RISA inoculator, RISA filtrator and densitometer, RISA plasmid preparator which can handle throughput of 40,000 samples in 17.5 h, and a high-throughput RISA thermal cycler which has four 384-well sites. The combination of these technologies allowed us to construct the RISA system consisting of 16 RISA sequencers, which can process 50,000 DNA samples per day. One haploid genome shotgun sequence of a higher organism, such as human, mouse, rat, domestic animals, and plants, can be

  2. Musical Sequences in Comics

    Directory of Open Access Journals (Sweden)

    Kieron Michael Brown

    2013-11-01

    Full Text Available Critical attention paid to the media of music and comics has historically focused on parallels between the temporal rhythm and pacing of music and the implied rhythm and temporality of comics (Eisner 2008, Godek 2007. Recent attention has begun to focus on both comics’ potential to represent the character of music (Whitted 2011 and the effects of musical images and themes on comics’ narratology (Peters 2013.    I suggest that analyses of comics that combine the traditional interplay of image and word with the use of elements of musical notation are able to shed further light on each of these areas, via the connotations and conventions of symbols pulled exclusively from the realms of music, and their integration with the other elements of the page in sequence.

  3. Solid phase sequencing of biopolymers

    Energy Technology Data Exchange (ETDEWEB)

    Cantor, Charles (Del Mar, CA); Koster, Hubert (La Jolla, CA)

    2010-09-28

    This invention relates to methods for detecting and sequencing target nucleic acid sequences, to mass modified nucleic acid probes and arrays of probes useful in these methods, and to kits and systems which contain these probes. Useful methods involve hybridizing the nucleic acids or nucleic acids which represent complementary or homologous sequences of the target to an array of nucleic acid probes. These probes comprise a single-stranded portion, an optional double-stranded portion and a variable sequence within the single-stranded portion. The molecular weights of the hybridized nucleic acids of the set can be determined by mass spectroscopy, and the sequence of the target determined from the molecular weights of the fragments. Nucleic acids whose sequences can be determined include DNA or RNA in biological samples such as patient biopsies and environmental samples. Probes may be fixed to a solid support such as a hybridization chip to facilitate automated molecular weight analysis and identification of the target sequence.

  4. WIDE-FIELD SURVEY OF EMISSION-LINE STARS IN IC 1396

    Energy Technology Data Exchange (ETDEWEB)

    Nakano, M. [Faculty of Education and Welfare Science, Oita University, Oita 870-1192 (Japan); Sugitani, K. [Graduate School of Natural Sciences, Nagoya City University, Mizuho-ku, Nagoya 467-8501 (Japan); Watanabe, M. [Department of Cosmosciences, Hokkaido University, Sapporo 060-0810 (Japan); Fukuda, N. [Department of Computer Simulation, Okayama University of Science, 1-1 Ridai-cho, Okayama 700-0005 (Japan); Ishihara, D. [Department of Physics, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8602 (Japan); Ueno, M., E-mail: mnakano@oita-u.ac.jp [Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, 3-1-1 Yoshino-dai, Chuo-ku, Sagamihara 252-5210 (Japan)

    2012-03-15

    We have made an extensive survey of emission-line stars in the IC 1396 H II region to investigate the low-mass population of pre-main-sequence (PMS) stars. A total of 639 H{alpha} emission-line stars were detected in an area of 4.2 deg{sup 2} and their i' photometry was measured. Their spatial distribution exhibits several aggregates near the elephant trunk globule (Rim A) and bright-rimmed clouds at the edge of the H II region (Rim B and SFO 37, 38, 39, 41), and near HD 206267, which is the main exciting star of the H II region. Based on the extinction estimated from the near-infrared color-color diagram, we have selected PMS star candidates associated with IC 1396. The age and mass were derived from the extinction-corrected color-magnitude diagram and theoretical PMS tracks. Most of our PMS candidates have ages of <3 Myr and masses of 0.2-0.6 M{sub Sun }. Although it appears that only a few stars were formed in the last 1 Myr in the east region of the exciting star, the age difference among subregions in our surveyed area is not clear from the statistical test. Our results may suggest that massive stars were born after the continuous formation of low-mass stars for 10 Myr. The birth of the exciting star could be the late stage of slow but contiguous star formation in the natal molecular cloud. It may have triggered the formation of many low-mass stars at the dense inhomogeneity in and around the H II region by a radiation-driven implosion.

  5. An XMM-Newton view of the young open cluster NGC 6231 - III. Optically faint X-ray sources

    Science.gov (United States)

    Sana, H.; Rauw, G.; Sung, H.; Gosset, E.; Vreux, J.-M.

    2007-05-01

    We discuss the properties of the X-ray sources with faint optical counterparts in the very young open cluster NGC 6231. From their positions in the Hertzsprung-Russell diagram, we find that the bulk of these objects probably consists of low-mass pre-main-sequence (PMS) stars with masses in the range 0.3-3.0 Msolar. The age distribution of these objects indicates that low-mass star formation in NGC 6231 started more than 10Myr ago and culminated in a starburst-like event about 1-4Myr ago when the bulk of the low-mass PMS stars as well as the massive cluster members formed. We find no evidence for a spatial age gradient that could point towards a sequential star formation process. Only a few X-ray sources have counterparts with a reddening exceeding the average value of the cluster or with infrared colours indicating the presence of a moderate near-IR excess. The X-ray spectra of the brightest PMS sources are best fitted by rather hard thermal plasma models and a significant fraction of these sources display flares in their light curve. The X-ray brightest flaring sources have decay times between 2 and 16ks. The X-ray selected PMS stars in NGC 6231 have logLX/Lbol values that increase strongly with decreasing bolometric luminosity and can reach a saturation level (logLX/Lbol ~ -2.4) for non-flaring sources and even more extreme values during flares. Based on observations with XMM-Newton, an ESA science mission with instruments and contributions directly funded by ESA member states and the USA (NASA). E-mail: hsana@eso.org ‡ FNRS Research Associate (Belgium).

  6. Solid phase sequencing of biopolymers

    Science.gov (United States)

    Cantor, Charles R.; Hubert, Koster

    2014-06-24

    This invention relates to methods for detecting and sequencing target nucleic acid sequences, to mass modified nucleic acid probes and arrays of probes useful in these methods, and to kits and systems which contain these probes. Useful methods involve hybridizing the nucleic acids or nucleic acids which represent complementary or homologous sequences of the target to an array of nucleic acid probes. These probes comprise a single-stranded portion, an optional double-stranded portion and a variable sequence within the single-stranded portion. The molecular weights of the hybridized nucleic acids of the set can be determined by mass spectroscopy, and the sequence of the target determined from the molecular weights of the fragments. Probes may be affixed to a solid support such as a hybridization chip to facilitate automated molecular weight analysis and identification of the target sequence.

  7. Graphene nanodevices for DNA sequencing

    Science.gov (United States)

    Heerema, Stephanie J.; Dekker, Cees

    2016-02-01

    Fast, cheap, and reliable DNA sequencing could be one of the most disruptive innovations of this decade, as it will pave the way for personalized medicine. In pursuit of such technology, a variety of nanotechnology-based approaches have been explored and established, including sequencing with nanopores. Owing to its unique structure and properties, graphene provides interesting opportunities for the development of a new sequencing technology. In recent years, a wide range of creative ideas for graphene sequencers have been theoretically proposed and the first experimental demonstrations have begun to appear. Here, we review the different approaches to using graphene nanodevices for DNA sequencing, which involve DNA passing through graphene nanopores, nanogaps, and nanoribbons, and the physisorption of DNA on graphene nanostructures. We discuss the advantages and problems of each of these key techniques, and provide a perspective on the use of graphene in future DNA sequencing technology.

  8. Short sequence motifs, overrepresented in mammalian conservednon-coding sequences

    Energy Technology Data Exchange (ETDEWEB)

    Minovitsky, Simon; Stegmaier, Philip; Kel, Alexander; Kondrashov,Alexey S.; Dubchak, Inna

    2007-02-21

    Background: A substantial fraction of non-coding DNAsequences of multicellular eukaryotes is under selective constraint. Inparticular, ~;5 percent of the human genome consists of conservednon-coding sequences (CNSs). CNSs differ from other genomic sequences intheir nucleotide composition and must play important functional roles,which mostly remain obscure.Results: We investigated relative abundancesof short sequence motifs in all human CNSs present in the human/mousewhole-genome alignments vs. three background sets of sequences: (i)weakly conserved or unconserved non-coding sequences (non-CNSs); (ii)near-promoter sequences (located between nucleotides -500 and -1500,relative to a start of transcription); and (iii) random sequences withthe same nucleotide composition as that of CNSs. When compared tonon-CNSs and near-promoter sequences, CNSs possess an excess of AT-richmotifs, often containing runs of identical nucleotides. In contrast, whencompared to random sequences, CNSs contain an excess of GC-rich motifswhich, however, lack CpG dinucleotides. Thus, abundance of short sequencemotifs in human CNSs, taken as a whole, is mostly determined by theiroverall compositional properties and not by overrepresentation of anyspecific short motifs. These properties are: (i) high AT-content of CNSs,(ii) a tendency, probably due to context-dependent mutation, of A's andT's to clump, (iii) presence of short GC-rich regions, and (iv) avoidanceof CpG contexts, due to their hypermutability. Only a small number ofshort motifs, overrepresented in all human CNSs are similar to bindingsites of transcription factors from the FOX family.Conclusion: Human CNSsas a whole appear to be too broad a class of sequences to possess strongfootprints of any short sequence-specific functions. Such footprintsshould be studied at the level of functional subclasses of CNSs, such asthose which flank genes with a particular pattern of expression. Overallproperties of CNSs are affected by

  9. Nonlinear analysis of biological sequences

    Energy Technology Data Exchange (ETDEWEB)

    Torney, D.C.; Bruno, W.; Detours, V. [and others

    1998-11-01

    This is the final report of a three-year, Laboratory Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The main objectives of this project involved deriving new capabilities for analyzing biological sequences. The authors focused on tabulating the statistical properties exhibited by Human coding DNA sequences and on techniques of inferring the phylogenetic relationships among protein sequences related by descent.

  10. Biosensors for DNA sequence detection

    Science.gov (United States)

    Vercoutere, Wenonah; Akeson, Mark

    2002-01-01

    DNA biosensors are being developed as alternatives to conventional DNA microarrays. These devices couple signal transduction directly to sequence recognition. Some of the most sensitive and functional technologies use fibre optics or electrochemical sensors in combination with DNA hybridization. In a shift from sequence recognition by hybridization, two emerging single-molecule techniques read sequence composition using zero-mode waveguides or electrical impedance in nanoscale pores.

  11. Blazar Sequence in Fermi Era

    Indian Academy of Sciences (India)

    Liang Chen

    2014-09-01

    In this paper, we review the latest research results on the topic of blazar sequence. It seems that the blazar sequence is phenomenally ruled out, while the theoretical blazar sequence still holds. We point out that black hole mass is a dominated parameter accounting for high-power-high-synchrotron-peaked and low-power-low-sychrotron-peaked blazars. Because most blazars have similar size of emission region, theoretical blazar sequence implies that the break of Spectral Energy Distribution (SED) is a cooling break in nature.

  12. ABS: Sequence alignment by scanning

    KAUST Repository

    Bonny, Mohamed Talal

    2011-08-01

    Sequence alignment is an essential tool in almost any computational biology research. It processes large database sequences and considered to be high consumers of computation time. Heuristic algorithms are used to get approximate but fast results. We introduce fast alignment algorithm, called Alignment By Scanning (ABS), to provide an approximate alignment of two DNA sequences. We compare our algorithm with the well-known alignment algorithms, the FASTA (which is heuristic) and the \\'Needleman-Wunsch\\' (which is optimal). The proposed algorithm achieves up to 76% enhancement in alignment score when it is compared with the FASTA Algorithm. The evaluations are conducted using different lengths of DNA sequences. © 2011 IEEE.

  13. Assembly sequencing with toleranced parts

    Energy Technology Data Exchange (ETDEWEB)

    Latombe, J.C. [Stanford Univ., CA (United States). Robotics Lab.; Wilson, R.H. [Sandia National Labs., Albuquerque, NM (United States). Intelligent Systems and Robotics Center

    1995-02-21

    The goal of assembly sequencing is to plan a feasible series of operations to construct a product from its individual parts. Previous research has thoroughly investigated assembly sequencing under the assumption that parts have nominal geometry. This paper considers the case where parts have toleranced geometry. Its main contribution is an efficient procedure that decides if a product admits an assembly sequence with infinite translations that is feasible for all possible instances of the components within the specified tolerances. If the product admits one such sequence, the procedure can also generate it. For the cases where there exists no such assembly sequence, another procedure is proposed which generates assembly sequences that are feasible only for some values of the toleranced dimensions. If this procedure produces no such sequence, then no instance of the product is assemblable. Finally, this paper analyzes the relation between assembly and disassembly sequences in the presence of toleranced parts. This work assumes a simple, but non-trivial tolerance language that falls short of capturing all imperfections of a manufacturing process. Hence, it is only one step toward assembly sequencing with toleranced parts.

  14. SNMR pulse sequence phase cycling

    Science.gov (United States)

    Walsh, David O; Grunewald, Elliot D

    2013-11-12

    Technologies applicable to SNMR pulse sequence phase cycling are disclosed, including SNMR acquisition apparatus and methods, SNMR processing apparatus and methods, and combinations thereof. SNMR acquisition may include transmitting two or more SNMR pulse sequences and applying a phase shift to a pulse in at least one of the pulse sequences, according to any of a variety cycling techniques. SNMR processing may include combining SNMR from a plurality of pulse sequences comprising pulses of different phases, so that desired signals are preserved and indesired signals are canceled.

  15. The ontology of biological sequences

    Directory of Open Access Journals (Sweden)

    Kelso Janet

    2009-11-01

    Full Text Available Abstract Background Biological sequences play a major role in molecular and computational biology. They are studied as information-bearing entities that make up DNA, RNA or proteins. The Sequence Ontology, which is part of the OBO Foundry, contains descriptions and definitions of sequences and their properties. Yet the most basic question about sequences remains unanswered: what kind of entity is a biological sequence? An answer to this question benefits formal ontologies that use the notion of biological sequences and analyses in computational biology alike. Results We provide both an ontological analysis of biological sequences and a formal representation that can be used in knowledge-based applications and other ontologies. We distinguish three distinct kinds of entities that can be referred to as "biological sequence": chains of molecules, syntactic representations such as those in biological databases, and the abstract information-bearing entities. For use in knowledge-based applications and inclusion in biomedical ontologies, we implemented the developed axiom system for use in automated theorem proving. Conclusion Axioms are necessary to achieve the main goal of ontologies: to formally specify the meaning of terms used within a domain. The axiom system for the ontology of biological sequences is the first elaborate axiom system for an OBO Foundry ontology and can serve as starting point for the development of more formal ontologies and ultimately of knowledge-based applications.

  16. Fast global sequence alignment technique

    KAUST Repository

    Bonny, Mohamed Talal

    2011-11-01

    Bioinformatics database is growing exponentially in size. Processing these large amount of data may take hours of time even if super computers are used. One of the most important processing tool in Bioinformatics is sequence alignment. We introduce fast alignment algorithm, called \\'Alignment By Scanning\\' (ABS), to provide an approximate alignment of two DNA sequences. We compare our algorithm with the wellknown sequence alignment algorithms, the \\'GAP\\' (which is heuristic) and the \\'Needleman-Wunsch\\' (which is optimal). The proposed algorithm achieves up to 51% enhancement in alignment score when it is compared with the GAP Algorithm. The evaluations are conducted using different lengths of DNA sequences. © 2011 IEEE.

  17. Sequence Algebra, Sequence Decision Diagrams and Dynamic Fault Trees

    Energy Technology Data Exchange (ETDEWEB)

    Rauzy, Antoine B., E-mail: Antoine.Rauzy@lix.polytechnique.f [LIX-CNRS, Computer Science, Ecole Polytechnique, 91128 Palaiseau Cedex (France)

    2011-07-15

    A large attention has been focused on the Dynamic Fault Trees in the past few years. By adding new gates to static (regular) Fault Trees, Dynamic Fault Trees aim to take into account dependencies among events. Merle et al. proposed recently an algebraic framework to give a formal interpretation to these gates. In this article, we extend Merle et al.'s work by adopting a slightly different perspective. We introduce Sequence Algebras that can be seen as Algebras of Basic Events, representing failures of non-repairable components. We show how to interpret Dynamic Fault Trees within this framework. Finally, we propose a new data structure to encode sets of sequences of Basic Events: Sequence Decision Diagrams. Sequence Decision Diagrams are very much inspired from Minato's Zero-Suppressed Binary Decision Diagrams. We show that all operations of Sequence Algebras can be performed on this data structure.

  18. Three-Distance Sequences with Three Symbols

    OpenAIRE

    SAKAMOTO, Kuniko

    2003-01-01

    We will show that every $3$ dimensional cutting sequence is a three-distance sequence, and there are uncountable many periodic or aperiodic three-distance sequences (with $3$-symbols) which are not $3$ dimensional cutting sequences.

  19. NSIT: novel sequence identification tool.

    Directory of Open Access Journals (Sweden)

    Benjarath Pupacdi

    Full Text Available Novel sequences are DNA sequences present in an individual's genome but absent in the human reference assembly. They are predicted to be biologically important, both individual and population specific, and consistent with the known human migration paths. Recent works have shown that an average person harbors 2-5 Mb of such sequences and estimated that the human pan-genome contains as high as 19-40 Mb of novel sequences. To identify them in a de novo genome assembly, some existing sequence aligners have been used but no computational method has been specifically proposed for this task. In this work, we developed NSIT (Novel Sequence Identification Tool, a software that can accurately and efficiently identify novel sequences in an individual's de novo whole genome assembly. We identified and characterized 1.1 Mb, 1.2 Mb, and 1.0 Mb of novel sequences in NA18507 (African, YH (Asian, and NA12878 (European de novo genome assemblies, respectively. Our results show very high concordance with the previous work using the respective reference assembly. In addition, our results using the latest human reference assembly suggest that the amount of novel sequences per individual may not be as high as previously reported. We additionally developed a graphical viewer for comparisons of novel sequence contents. The viewer also helped in identifying sequence contamination; we found 130 kb of Epstein-Barr virus sequence in the previously published NA18507 novel sequences as well as 287 kb of zebrafish repeats in NA12878 de novo assembly. NSIT requires [Formula: see text]2GB of RAM and 1.5-2 hrs on a commodity desktop. The program is applicable to input assemblies with varying contig/scaffold sizes, ranging from 100 bp to as high as 50 Mb. It works in both 32-bit and 64-bit systems and outperforms, by large margins, other fast sequence aligners previously applied to this task. To our knowledge, NSIT is the first software designed specifically for novel sequence

  20. X-ray Observations of Eight Young Open Star Clusters: I. Membership and X-ray Luminosity

    Indian Academy of Sciences (India)

    Himali Bhatt; J. C. Pandey; K. P. Singh; Ram Sagar; Brijesh Kumar

    2013-12-01

    We present a detailed investigation of X-ray source contents of eight young open clusters with ages between 4 to 46 Myr using archival X-ray data from XMM-NEWTON. The probable cluster memberships of the X-ray sources have been established on the basis of multi-wavelength archival data, and samples of 152 pre-main sequence (PMS) low mass (< 2⊙), 36 intermediate mass (2-10⊙) and 16 massive (> 10⊙) stars have been generated. X-ray spectral analyses of high mass stars reveal the presence of high temperature plasma with temperature < 2 keV, and mean /bol of 10-6.9. In the case of PMS low mass stars, the plasma temperatures have been found to be in the range of 0.2 keV to 3 keV with a median value of ∼ 1.3 keV, with no significant difference in plasma temperatures during their evolution from 4 to 46 Myr. The X-ray luminosity distributions of the PMS low mass stars have been found to be similar in the young star clusters under study. This may suggest a nearly uniform X-ray activity in the PMS low mass stars of ages ∼ 4–14 Myr. These observed values of /bol are found to have a mean value of 10-3.6 ± 0.4, which is below the X-ray saturation level. The /bol values for the PMS low mass stars are well correlated with their bolometric luminosities, that implies its dependence on the internal structure of the low mass stars. The difference between the X-ray luminosity distributions of the intermediate mass stars and the PMS low mass stars has not been found to be statistically significant. Their /bol values, however have been found to be significantly different from each other with a confidence level greater than 99.999% and the strength of X-ray activity in the intermediate mass stars is found to be lower compared to the low mass stars. However, the possibility of X-ray emission from the intermediate mass stars due to a low mass star in close proximity of the intermediate mass star can not be ruled out.

  1. PERIODIC COMPLEMENTARY BINARY SEQUENCE PAIRS

    Institute of Scientific and Technical Information of China (English)

    XuChengqian; ZhaoXiaoqun

    2002-01-01

    A new set of binary sequences-Periodic Complementary Binary Sequence Pair (PCSP)is proposed .A new class of block design-Difference Family Pair (DFP)is also proposed .The relationship between PCSP and DFP,the properties and exising conditions of PCSP and the recursive constructions for PCSP are given.

  2. PERIODIC COMPLEMENTARY BINARY SEQUENCE PAIRS

    Institute of Scientific and Technical Information of China (English)

    Xu Chengqian; Zhao Xiaoqun

    2002-01-01

    A new set of binary sequences-Periodic Complementary Binary Sequence Pair (PCSP) is proposed. A new class of block design-Difference Family Pair (DFP) is also proposed.The relationship between PCSP and DFP, the properties and existing conditions of PCSP and the recursive constructions for PCSP are given.

  3. DNA Sequencing Sensors: An Overview

    Directory of Open Access Journals (Sweden)

    Jose Antonio Garrido-Cardenas

    2017-03-01

    Full Text Available The first sequencing of a complete genome was published forty years ago by the double Nobel Prize in Chemistry winner Frederick Sanger. That corresponded to the small sized genome of a bacteriophage, but since then there have been many complex organisms whose DNA have been sequenced. This was possible thanks to continuous advances in the fields of biochemistry and molecular genetics, but also in other areas such as nanotechnology and computing. Nowadays, sequencing sensors based on genetic material have little to do with those used by Sanger. The emergence of mass sequencing sensors, or new generation sequencing (NGS meant a quantitative leap both in the volume of genetic material that was able to be sequenced in each trial, as well as in the time per run and its cost. One can envisage that incoming technologies, already known as fourth generation sequencing, will continue to cheapen the trials by increasing DNA reading lengths in each run. All of this would be impossible without sensors and detection systems becoming smaller and more precise. This article provides a comprehensive overview on sensors for DNA sequencing developed within the last 40 years.

  4. Gambling strategies for random sequences

    OpenAIRE

    George Davie

    2010-01-01

    There is a general consensus that it is not possible to gamble successfully against a random se-quence. This consensus is based on results from probability theory that all gambling systems arein some sense futile and the idea that at any stage of the sequence, the next outcome is entirelyunpredictable.

  5. Sequence conserved for subcellular localization

    Science.gov (United States)

    Nair, Rajesh; Rost, Burkhard

    2002-01-01

    The more proteins diverged in sequence, the more difficult it becomes for bioinformatics to infer similarities of protein function and structure from sequence. The precise thresholds used in automated genome annotations depend on the particular aspect of protein function transferred by homology. Here, we presented the first large-scale analysis of the relation between sequence similarity and identity in subcellular localization. Three results stood out: (1) The subcellular compartment is generally more conserved than what might have been expected given that short sequence motifs like nuclear localization signals can alter the native compartment; (2) the sequence conservation of localization is similar between different compartments; and (3) it is similar to the conservation of structure and enzymatic activity. In particular, we found the transition between the regions of conserved and nonconserved localization to be very sharp, although the thresholds for conservation were less well defined than for structure and enzymatic activity. We found that a simple measure for sequence similarity accounting for pairwise sequence identity and alignment length, the HSSP distance, distinguished accurately between protein pairs of identical and different localizations. In fact, BLAST expectation values outperformed the HSSP distance only for alignments in the subtwilight zone. We succeeded in slightly improving the accuracy of inferring localization through homology by fine tuning the thresholds. Finally, we applied our results to the entire SWISS-PROT database and five entirely sequenced eukaryotes. PMID:12441382

  6. Bayesian analysis of binary sequences

    Science.gov (United States)

    Torney, David C.

    2005-03-01

    This manuscript details Bayesian methodology for "learning by example", with binary n-sequences encoding the objects under consideration. Priors prove influential; conformable priors are described. Laplace approximation of Bayes integrals yields posterior likelihoods for all n-sequences. This involves the optimization of a definite function over a convex domain--efficiently effectuated by the sequential application of the quadratic program.

  7. Chameleon sequences in neurodegenerative diseases

    Energy Technology Data Exchange (ETDEWEB)

    Bahramali, Golnaz [Institute of Biochemistry and Biophysics, University of Tehran, Tehran (Iran, Islamic Republic of); Goliaei, Bahram, E-mail: goliaei@ut.ac.ir [Institute of Biochemistry and Biophysics, University of Tehran, Tehran (Iran, Islamic Republic of); Minuchehr, Zarrin, E-mail: minuchehr@nigeb.ac.ir [Department of Systems Biotechnology, National Institute of Genetic Engineering and Biotechnology, (NIGEB), Tehran (Iran, Islamic Republic of); Salari, Ali [Department of Systems Biotechnology, National Institute of Genetic Engineering and Biotechnology, (NIGEB), Tehran (Iran, Islamic Republic of)

    2016-03-25

    Chameleon sequences can adopt either alpha helix sheet or a coil conformation. Defining chameleon sequences in PDB (Protein Data Bank) may yield to an insight on defining peptides and proteins responsible in neurodegeneration. In this research, we benefitted from the large PDB and performed a sequence analysis on Chameleons, where we developed an algorithm to extract peptide segments with identical sequences, but different structures. In order to find new chameleon sequences, we extracted a set of 8315 non-redundant protein sequences from the PDB with an identity less than 25%. Our data was classified to “helix to strand (HE)”, “helix to coil (HC)” and “strand to coil (CE)” alterations. We also analyzed the occurrence of singlet and doublet amino acids and the solvent accessibility in the chameleon sequences; we then sorted out the proteins with the most number of chameleon sequences and named them Chameleon Flexible Proteins (CFPs) in our dataset. Our data revealed that Gly, Val, Ile, Tyr and Phe, are the major amino acids in Chameleons. We also found that there are proteins such as Insulin Degrading Enzyme IDE and GTP-binding nuclear protein Ran (RAN) with the most number of chameleons (640 and 405 respectively). These proteins have known roles in neurodegenerative diseases. Therefore it can be inferred that other CFP's can serve as key proteins in neurodegeneration, and a study on them can shed light on curing and preventing neurodegenerative diseases.

  8. Rapid Diagnostics of Onboard Sequences

    Science.gov (United States)

    Starbird, Thomas W.; Morris, John R.; Shams, Khawaja S.; Maimone, Mark W.

    2012-01-01

    Keeping track of sequences onboard a spacecraft is challenging. When reviewing Event Verification Records (EVRs) of sequence executions on the Mars Exploration Rover (MER), operators often found themselves wondering which version of a named sequence the EVR corresponded to. The lack of this information drastically impacts the operators diagnostic capabilities as well as their situational awareness with respect to the commands the spacecraft has executed, since the EVRs do not provide argument values or explanatory comments. Having this information immediately available can be instrumental in diagnosing critical events and can significantly enhance the overall safety of the spacecraft. This software provides auditing capability that can eliminate that uncertainty while diagnosing critical conditions. Furthermore, the Restful interface provides a simple way for sequencing tools to automatically retrieve binary compiled sequence SCMFs (Space Command Message Files) on demand. It also enables developers to change the underlying database, while maintaining the same interface to the existing applications. The logging capabilities are also beneficial to operators when they are trying to recall how they solved a similar problem many days ago: this software enables automatic recovery of SCMF and RML (Robot Markup Language) sequence files directly from the command EVRs, eliminating the need for people to find and validate the corresponding sequences. To address the lack of auditing capability for sequences onboard a spacecraft during earlier missions, extensive logging support was added on the Mars Science Laboratory (MSL) sequencing server. This server is responsible for generating all MSL binary SCMFs from RML input sequences. The sequencing server logs every SCMF it generates into a MySQL database, as well as the high-level RML file and dictionary name inputs used to create the SCMF. The SCMF is then indexed by a hash value that is automatically included in all command

  9. Spatiotemporal correlations of aftershock sequences

    CERN Document Server

    Peixoto, Tiago P; Davidsen, Jörn

    2010-01-01

    Aftershock sequences are of particular interest in seismic research since they may condition seismic activity in a given region over long time spans. While they are typically identified with periods of enhanced seismic activity after a large earthquake as characterized by the Omori law, our knowledge of the spatiotemporal correlations between events in an aftershock sequence is limited. Here, we study the spatiotemporal correlations of two aftershock sequences form California (Parkfield and Hector Mine) using the recently introduced concept of "recurrent" events. We find that both sequences have very similar properties and that most of them are captured by the space-time epidemic-type aftershock sequence (ETAS) model if one takes into account catalog incompleteness. However, the stochastic model does not capture the spatiotemporal correlations leading to the observed structure of seismicity on small spatial scales.

  10. Quantum Exchangeable Sequences of Algebras

    CERN Document Server

    Curran, Stephen

    2008-01-01

    We extend the notion of quantum exchangeability, introduced by K\\"ostler and Speicher in arXiv:0807.0677, to sequences (\\rho_1,\\rho_2,...c) of homomorphisms from an algebra C into a noncommutative probability space (A,\\phi), and prove a free de Finetti theorem: an infinite quantum exchangeable sequence (\\rho_1,\\rho_2,...c) is freely independent and identically distributed with respect to a conditional expectation. As a corollary we obtain a free analogue of the Hewitt Savage zero-one law. As in the classical case, the theorem fails for finite sequences. We give a characterization of finite quantum exchangeable sequences, which can be viewed as a noncommutative analogue of sampling without replacement. We then give an approximation to how far a finite quantum exchangeable sequence is from being freely independent with amalgamation.

  11. Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD)

    Science.gov (United States)

    ... have ever been treated for a mood or anxiety disorder, substance abuse, headaches, chronic fatigue or other medical conditions that can sometimes get worse a few days before a women’s menstrual period. Is there anything I can do ...

  12. Genes May Play Role in More Severe Form of PMS

    Science.gov (United States)

    ... white blood cells. They found a complex of genes that acts differently in women with the disorder compared to women without it. Dr. David Goldman, of the U.S. National Institute on Alcohol Abuse and Alcoholism, worked with Schmidt on the study. "This is ...

  13. Hypo-analytic structures local theory (PMS-40)

    CERN Document Server

    Treves, François

    2014-01-01

    In Hypo-Analytic Structures Franois Treves provides a systematic approach to the study of the differential structures on manifolds defined by systems of complex vector fields. Serving as his main examples are the elliptic complexes, among which the De Rham and Dolbeault are the best known, and the tangential Cauchy-Riemann operators. Basic geometric entities attached to those structures are isolated, such as maximally real submanifolds and orbits of the system. Treves discusses the existence, uniqueness, and approximation of local solutions to homogeneous and inhomogeneous equations and delimits their supports. The contents of this book consist of many results accumulated in the last decade by the author and his collaborators, but also include classical results, such as the Newlander-Nirenberg theorem. The reader will find an elementary description of the FBI transform, as well as examples of its use. Treves extends the main approximation and uniqueness results to first-order nonlinear equations by means of ...

  14. Did Not Wait Patient Management Strategy (DNW PMS) Study.

    LENUS (Irish Health Repository)

    2012-02-01

    Objectives This study was undertaken to assess the usefulness of senior emergency medicine specialists\\' review of all \\'did not wait\\' (DNW) patients\\' triage notes and the recall of at-risk patients. Methods A prospective study of all DNW patients was performed from 1 January to 31 December 2008. Following a daily review of charts of those who failed to wait to be seen, those patients considered to be at risk of adverse outcome were contacted by the liaison team and advised to return. Data were gathered on all DNW patients on the Oracle database and interrogated using the Diver solution. Results 2872 (6.3%) of 45 959 patients did not wait to be seen. 107 (3.7%) were recalled on the basis of senior emergency medicine doctor review of the patients\\' triage notes. Variables found to be associated with increased likelihood of being recalled included triage category (p<0.001), male sex (p<0.004) and certain clinical presentations. The presenting complaints associated with being recalled were chest pain (p<0.001) and alcohol\\/drug overdose (p=0.001). 9.4% of DNW patients required admission following recall. Conclusion The systematic senior doctor review of triage notes led to 3.7% of patients who failed to wait being recalled. 9.4% of those recalled required acute admission. The daily review of DNW patients\\' triage notes and the recalling of at-risk patients is a valuable addition to our risk management strategy.

  15. Did Not Wait Patient Management Strategy (DNW PMS) Study.

    LENUS (Irish Health Repository)

    O'Keeffe, Fran

    2011-06-14

    Objectives This study was undertaken to assess the usefulness of senior emergency medicine specialists\\' review of all \\'did not wait\\' (DNW) patients\\' triage notes and the recall of at-risk patients. Methods A prospective study of all DNW patients was performed from 1 January to 31 December 2008. Following a daily review of charts of those who failed to wait to be seen, those patients considered to be at risk of adverse outcome were contacted by the liaison team and advised to return. Data were gathered on all DNW patients on the Oracle database and interrogated using the Diver solution. Results 2872 (6.3%) of 45 959 patients did not wait to be seen. 107 (3.7%) were recalled on the basis of senior emergency medicine doctor review of the patients\\' triage notes. Variables found to be associated with increased likelihood of being recalled included triage category (p<0.001), male sex (p<0.004) and certain clinical presentations. The presenting complaints associated with being recalled were chest pain (p<0.001) and alcohol\\/drug overdose (p=0.001). 9.4% of DNW patients required admission following recall. Conclusion The systematic senior doctor review of triage notes led to 3.7% of patients who failed to wait being recalled. 9.4% of those recalled required acute admission. The daily review of DNW patients\\' triage notes and the recalling of at-risk patients is a valuable addition to our risk management strategy.

  16. Automated Manpower Analysis and Personnel Management System (AMA/PMS).

    OpenAIRE

    Schwind, Cynthia E.

    1992-01-01

    Approved for public release; distribution is unlimited In a peacetime environment of increasing budget cuts resulting in reduced manning levels, active management of limited manpower assets is vital to ensure mission accomplishment and battle readiness. Manpower analysis is the process by which an activity's manpower assets are matched to or balanced against authorized billets to determine strengths and weaknesses in manning structure. Manpower analysis must be perform...

  17. PMS : Photosystem I electron donor or fluorescence quencher

    NARCIS (Netherlands)

    Wientjes, Emilie; Croce, Roberta

    2012-01-01

    Light energy harvested by the pigments in Photosystem I (PSI) is used for charge separation in the reaction center (RC), after which the positive charge resides on a special chlorophyll dimer called P700. In studies on the PSI trapping kinetics, P700(+) is usually chemically reduced to re-open the R

  18. The IC 5146 star forming complex and its surroundings with 2MASS, WISE and Spitzer

    CERN Document Server

    Nunes, N A; Bica, E

    2016-01-01

    Throughout the last decade sensitive infrared observations obtained by the Spitzer Space Telescope significantly increased the known population of YSOs associated with nearby molecular clouds. With such a census recent studies have characterized pre-main sequence stars (PMS) and determined parame- ters from different wavelengths. Given the restricted Spitzer coverage of some of these clouds, relative to their extended regions, these YSO populations may represent a limited view of star formation in these regions. We are taking advantage of mid-infrared observations from the NASA Wide Field Infrared Survey Explorer (WISE), which provides an all sky view and therefore full coverage of the nearby clouds, to assess the degree to which their currently known YSO population may be representative of a more complete population. We extend the well established classification method of the Spitzer Legacy teams to archived WISE observations. We have adopted 2MASS photometry as a standard catalogue for comparisons. Besides ...

  19. A Hubble View of Star Forming Regions in the Magellanic Clouds

    CERN Document Server

    Gouliermis, D A; Brandner, W; Rosa, M R; Dolphin, A E; Schmalzl, M; Hennekemper, E; Zinnecker, H; Panagia, N; Chu, Y -H; Brandl, B; Quanz, S P; Robberto, M; De Marchi, G; Gruendl, R A; Romaniello, M

    2007-01-01

    The Magellanic Clouds (MCs) offer an outstanding variety of young stellar associations, in which large samples of low-mass stars (with masses less than 1 solar mass) currently in the act of formation can be resolved and explored sufficiently with the Hubble Space Telescope. These pre-main sequence (PMS) stars provide a unique snapshot of the star formation process, as it is being recorded for the last 20 Myr, and they give important information on the low-mass Initial Mass Function (IMF) of their host environments. We present the latest results from observations with the Advanced Camera for Surveys (ACS) of such star-forming regions in the MCs, and discuss the importance of Hubble}for a comprehensive collection of substantial information on the most recent low-mass star formation and the low-mass IMF in the MCs.

  20. Modeling the Near-Infrared Luminosity Functions of Young Stellar Clusters

    CERN Document Server

    Münch, A; Lada, C J; Muench, August A.; Lada, Elizabeth A.; Lada, Charles J.

    1999-01-01

    We present the results of numerical experiments designed to evaluate the usefulness of near-infrared luminosity functions for constraining the Initial Mass Function (IMF) of young stellar populations. From this numerical modeling, we find that the luminosity function of a young stellar population is considerably more sensitive to variations in the underlying initial mass function than to either variations in the star forming history or assumed pre-main-sequence (PMS) mass-to-luminosity relation. To illustrate the potential effectiveness of using the KLF of a young cluster to constrain its IMF, we model the observed K band luminosity function of the nearby Trapezium cluster. Our derived mass function for the Trapezium spans two orders of magnitude in stellar mass (5 Msun to 0.02 Msun), has a peak near the hydrogen burning limit, and has an IMF for Brown Dwarfs which steadily decreases with decreasing mass.

  1. Ossification sequence heterochrony among amphibians.

    Science.gov (United States)

    Harrington, Sean M; Harrison, Luke B; Sheil, Christopher A

    2013-01-01

    Heterochrony is an important mechanism in the evolution of amphibians. Although studies have centered on the relationship between size and shape and the rates of development, ossification sequence heterochrony also may have been important. Rigorous, phylogenetic methods for assessing sequence heterochrony are relatively new, and a comprehensive study of the relative timing of ossification of skeletal elements has not been used to identify instances of sequence heterochrony across Amphibia. In this study, a new version of the program Parsimov-based genetic inference (PGi) was used to identify shifts in ossification sequences across all extant orders of amphibians, for all major structural units of the skeleton. PGi identified a number of heterochronic sequence shifts in all analyses, the most interesting of which seem to be tied to differences in metamorphic patterns among major clades. Early ossification of the vomer, premaxilla, and dentary is retained by Apateon caducus and members of Gymnophiona and Urodela, which lack the strongly biphasic development seen in anurans. In contrast, bones associated with the jaws and face were identified as shifting late in the ancestor of Anura. The bones that do not shift late, and thereby occupy the earliest positions in the anuran cranial sequence, are those in regions of the skull that undergo the least restructuring throughout anuran metamorphosis. Additionally, within Anura, bones of the hind limb and pelvic girdle were also identified as shifting early in the sequence of ossification, which may be a result of functional constraints imposed by the drastic metamorphosis of most anurans.

  2. A Criterion for Regular Sequences

    Indian Academy of Sciences (India)

    D P Patil; U Storch; J Stückrad

    2004-05-01

    Let be a commutative noetherian ring and $f_1,\\ldots,f_r \\in R$. In this article we give (cf. the Theorem in $\\mathcal{x}$2) a criterion for $f_1,\\ldots,f_r$ to be regular sequence for a finitely generated module over which strengthens and generalises a result in [2]. As an immediate consequence we deduce that if $V(g_1,\\ldots,g_r) \\subseteq V(f_1,\\ldots,f_r)$ in Spec and if $f_1,\\ldots,f_r$ is a regular sequence in , then $g_1,\\ldots,g_r$ is also a regular sequence in .

  3. Weak disorder in Fibonacci sequences

    Energy Technology Data Exchange (ETDEWEB)

    Ben-Naim, E [Theoretical Division and Center for Nonlinear Studies, Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Krapivsky, P L [Department of Physics and Center for Molecular Cybernetics, Boston University, Boston, MA 02215 (United States)

    2006-05-19

    We study how weak disorder affects the growth of the Fibonacci series. We introduce a family of stochastic sequences that grow by the normal Fibonacci recursion with probability 1 - {epsilon}, but follow a different recursion rule with a small probability {epsilon}. We focus on the weak disorder limit and obtain the Lyapunov exponent that characterizes the typical growth of the sequence elements, using perturbation theory. The limiting distribution for the ratio of consecutive sequence elements is obtained as well. A number of variations to the basic Fibonacci recursion including shift, doubling and copying are considered. (letter to the editor)

  4. Sejong Open Cluster Survey (SOS). II. IC 1848 Cluster in the H II Region W5 West

    CERN Document Server

    Lim, Beomdu; Kim, Jinyoung S; Bessell, Michael S; Karimov, Rivkat

    2013-01-01

    IC 1848 is one of the young open clusters in the giant star forming Cas OB6 association. Several interesting aspects relating to star formation processes in giant star forming regions attracted us to study the initial mass function (IMF), star formation mode, and properties of pre-main sequence stars (PMS). A UBVI and H alpha photometric study of the young open cluster IC 1848 was conducted as part of the "Sejong Open cluster Survey" (SOS). We have selected 105 early-type members from photometric diagrams. Their mean reddening is = 0.660 +/- 0.054 mag. Using the published photometric data with near- and mid-infrared archival data we confirmed the normal reddening law (R_V = 3.1) toward the cluster (IC 1848). A careful zero-age main sequence fitting gives a distance modulus of V_0 - M_V = 11.7 +/- 0.2 mag, equivalent to 2.2 +/- 0.2 kpc. H alpha photometry and the list of young stellar objects identified by Koenig et al. permitted us to select a large number of PMS stars comprising 196 H alpha emission stars, ...

  5. Star formation in 30 Doradus

    CERN Document Server

    De Marchi, Guido; Panagia, Nino; Beccari, Giacomo; Spezzi, Loredana; Sirianni, Marco; Andersen, Morten; Mutchler, Max; Balick, Bruce; Dopita, Michael A; Frogel, Jay A; Whitmore, Bradley C; Bond, Howard; Clazetti, Daniela; Carollo, C Marcella; Disney, Michael J; Hall, Donald N B; Holtzman, Jon A; Kimble, Randy A; McCarthy, Patrick J; O'Connell, Robert W; Saha, Abhijit; Silk, Joseph I; Trauger, John T; Walker, Alistair R; Windhorst, Rogier A; Young, Erick T

    2011-01-01

    Using observations obtained with the Wide Field Camera 3 (WFC3) on board the Hubble Space Telescope (HST), we have studied the properties of the stellar populations in the central regions of 30 Dor, in the Large Magellanic Cloud. The observations clearly reveal the presence of considerable differential extinction across the field. We characterise and quantify this effect using young massive main sequence stars to derive a statistical reddening correction for most objects in the field. We then search for pre-main sequence (PMS) stars by looking for objects with a strong (> 4 sigma) Halpha excess emission and find about 1150 of them over the entire field. Comparison of their location in the Hertzsprung-Russell diagram with theoretical PMS evolutionary tracks for the appropriate metallicity reveals that about one third of these objects are younger than ~4Myr, compatible with the age of the massive stars in the central ionising cluster R136, whereas the rest have ages up to ~30Myr, with a median age of ~12Myr. Th...

  6. The Initial Mass Function of the Stellar Association NGC 602 in the Small Magellanic Cloud with Hubble Space Telescope ACS Observations

    CERN Document Server

    Schmalzl, Markus; Dolphin, Andrew E; Henning, Thomas

    2008-01-01

    We present our photometric study of the stellar association NGC 602 in the wing of the Small Magellanic Cloud (SMC). The data were taken in the filters F555W and F814W using the Advanced Camera for Surveys (ACS) on-board the Hubble Space Telescope (HST). Photometry was performed using the ACS module of the stellar photometry package DOLPHOT. We detected more than 5,500 stars with a magnitude range of 14 \\lsim m_{555} \\lsim 28 mag. Three prominent stellar concentrations are identified with star counts in the observed field, the association NGC 602 itself, and two clusters, one of them not being currently in any known catalog. The Color-Magnitude Diagrams (CMDs) of both clusters show features typical for young open clusters, while that of the association reveals bright main sequence (MS) and faint pre-main sequence (PMS) stars as the members of the system. We construct the initial mass spectrum (IMS) of the association by applying an age-independent method of counting the PMS stars within evolutionary tracks, w...

  7. The evolution of X-ray emission in young stars

    CERN Document Server

    Preibisch, T; Preibisch, Thomas; Feigelson, Eric D.

    2005-01-01

    We study the relation between age and magnetic activity in late-type pre-main sequence (PMS) stars, for the first time using mass-stratified subsamples. The effort is based on the Chandra Orion Ultradeep Project (COUP) which provides very sensitive and homogenous X-ray data on a uniquely large sample of 481 optically well-characterized low-extinction low-mass members of the Orion Nebula Cluster, for which individual stellar masses and ages could be determined. More than 98 percent of the stars in this sample are detected as X-ray sources. Within the PMS phase for stellar ages in the range $\\sim 0.1-10$ Myr, we establish a mild decay in activity with stellar age $\\tau$ roughly as $L_{\\rm X} \\propto \\tau^{-1/3}$. On longer timescales, when the Orion stars are compared to main sequence stars, the X-ray luminosity decay law for stars in the $0.5 < M < 1.2$ M$_\\odot$ mass range is more rapid with $L_{\\rm X} \\propto \\tau^{-0.75}$ over the wide range of ages $5 < \\log \\tau < 9.5$ yr. The magnetic activit...

  8. ISIS Individualized Support In Sequencing

    NARCIS (Netherlands)

    Drachsler, Hendrik; Hummel, Hans

    2007-01-01

    Drachsler, H., & Hummel, H. G. K. (2007). ISIS Individualized Support In Sequencing. Presentation given during the PIP meeting on March 22, 2007. Open University of the Netherlands: Heerlen, The Netherlands.

  9. Molecular beacon sequence design algorithm.

    Science.gov (United States)

    Monroe, W Todd; Haselton, Frederick R

    2003-01-01

    A method based on Web-based tools is presented to design optimally functioning molecular beacons. Molecular beacons, fluorogenic hybridization probes, are a powerful tool for the rapid and specific detection of a particular nucleic acid sequence. However, their synthesis costs can be considerable. Since molecular beacon performance is based on its sequence, it is imperative to rationally design an optimal sequence before synthesis. The algorithm presented here uses simple Microsoft Excel formulas and macros to rank candidate sequences. This analysis is carried out using mfold structural predictions along with other free Web-based tools. For smaller laboratories where molecular beacons are not the focus of research, the public domain algorithm described here may be usefully employed to aid in molecular beacon design.

  10. Classification of Base Sequences (+1,

    Directory of Open Access Journals (Sweden)

    Dragomir Ž. Ðoković

    2010-01-01

    Full Text Available Base sequences BS(+1, are quadruples of {±1}-sequences (;;;, with A and B of length +1 and C and D of length n, such that the sum of their nonperiodic autocor-relation functions is a -function. The base sequence conjecture, asserting that BS(+1, exist for all n, is stronger than the famous Hadamard matrix conjecture. We introduce a new definition of equivalence for base sequences BS(+1, and construct a canonical form. By using this canonical form, we have enumerated the equivalence classes of BS(+1, for ≤30. As the number of equivalence classes grows rapidly (but not monotonically with n, the tables in the paper cover only the cases ≤13.

  11. DNA Sequencing Using capillary Electrophoresis

    Energy Technology Data Exchange (ETDEWEB)

    Dr. Barry Karger

    2011-05-09

    The overall goal of this program was to develop capillary electrophoresis as the tool to be used to sequence for the first time the Human Genome. Our program was part of the Human Genome Project. In this work, we were highly successful and the replaceable polymer we developed, linear polyacrylamide, was used by the DOE sequencing lab in California to sequence a significant portion of the human genome using the MegaBase multiple capillary array electrophoresis instrument. In this final report, we summarize our efforts and success. We began our work by separating by capillary electrophoresis double strand oligonucleotides using cross-linked polyacrylamide gels in fused silica capillaries. This work showed the potential of the methodology. However, preparation of such cross-linked gel capillaries was difficult with poor reproducibility, and even more important, the columns were not very stable. We improved stability by using non-cross linked linear polyacrylamide. Here, the entangled linear chains could move when osmotic pressure (e.g. sample injection) was imposed on the polymer matrix. This relaxation of the polymer dissipated the stress in the column. Our next advance was to use significantly lower concentrations of the linear polyacrylamide that the polymer could be automatically blown out after each run and replaced with fresh linear polymer solution. In this way, a new column was available for each analytical run. Finally, while testing many linear polymers, we selected linear polyacrylamide as the best matrix as it was the most hydrophilic polymer available. Under our DOE program, we demonstrated initially the success of the linear polyacrylamide to separate double strand DNA. We note that the method is used even today to assay purity of double stranded DNA fragments. Our focus, of course, was on the separation of single stranded DNA for sequencing purposes. In one paper, we demonstrated the success of our approach in sequencing up to 500 bases. Other

  12. Pythagorean Triples from Harmonic Sequences.

    Science.gov (United States)

    DiDomenico, Angelo S.; Tanner, Randy J.

    2001-01-01

    Shows how all primitive Pythagorean triples can be generated from harmonic sequences. Use inductive and deductive reasoning to explore how Pythagorean triples are connected with another area of mathematics. (KHR)

  13. Overview of Sequence Data Formats.

    Science.gov (United States)

    Zhang, Hongen

    2016-01-01

    Next-generation sequencing experiment can generate billions of short reads for each sample and processing of the raw reads will add more information. Various file formats have been introduced/developed in order to store and manipulate this information. This chapter presents an overview of the file formats including FASTQ, FASTA, SAM/BAM, GFF/GTF, BED, and VCF that are commonly used in analysis of next-generation sequencing data.

  14. Structural Complexity of DNA Sequence

    Directory of Open Access Journals (Sweden)

    Cheng-Yuan Liou

    2013-01-01

    Full Text Available In modern bioinformatics, finding an efficient way to allocate sequence fragments with biological functions is an important issue. This paper presents a structural approach based on context-free grammars extracted from original DNA or protein sequences. This approach is radically different from all those statistical methods. Furthermore, this approach is compared with a topological entropy-based method for consistency and difference of the complexity results.

  15. Nanogrid rolling circle DNA sequencing

    Energy Technology Data Exchange (ETDEWEB)

    Church, George M.; Porreca, Gregory J.; Shendure, Jay; Rosenbaum, Abraham Meir

    2017-04-18

    The present invention relates to methods for sequencing a polynucleotide immobilized on an array having a plurality of specific regions each having a defined diameter size, including synthesizing a concatemer of a polynucleotide by rolling circle amplification, wherein the concatemer has a cross-sectional diameter greater than the diameter of a specific region, immobilizing the concatemer to the specific region to make an immobilized concatemer, and sequencing the immobilized concatemer.

  16. Pig genome sequence - analysis and publication strategy

    NARCIS (Netherlands)

    Archibald, A.L.; Bolund, L.; Churcher, C.; Fredholm, M.; Groenen, M.A.M.; Harlizius, B.

    2010-01-01

    Background - The pig genome is being sequenced and characterised under the auspices of the Swine Genome Sequencing Consortium. The sequencing strategy followed a hybrid approach combining hierarchical shotgun sequencing of BAC clones and whole genome shotgun sequencing. Results - Assemblies of the B

  17. Long-range barcode labeling-sequencing

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Feng; Zhang, Tao; Singh, Kanwar K.; Pennacchio, Len A.; Froula, Jeff L.; Eng, Kevin S.

    2016-10-18

    Methods for sequencing single large DNA molecules by clonal multiple displacement amplification using barcoded primers. Sequences are binned based on barcode sequences and sequenced using a microdroplet-based method for sequencing large polynucleotide templates to enable assembly of haplotype-resolved complex genomes and metagenomes.

  18. Sequencing and comparative analysis of the gorilla MHC genomic sequence.

    Science.gov (United States)

    Wilming, Laurens G; Hart, Elizabeth A; Coggill, Penny C; Horton, Roger; Gilbert, James G R; Clee, Chris; Jones, Matt; Lloyd, Christine; Palmer, Sophie; Sims, Sarah; Whitehead, Siobhan; Wiley, David; Beck, Stephan; Harrow, Jennifer L

    2013-01-01

    Major histocompatibility complex (MHC) genes play a critical role in vertebrate immune response and because the MHC is linked to a significant number of auto-immune and other diseases it is of great medical interest. Here we describe the clone-based sequencing and subsequent annotation of the MHC region of the gorilla genome. Because the MHC is subject to extensive variation, both structural and sequence-wise, it is not readily amenable to study in whole genome shotgun sequence such as the recently published gorilla genome. The variation of the MHC also makes it of evolutionary interest and therefore we analyse the sequence in the context of human and chimpanzee. In our comparisons with human and re-annotated chimpanzee MHC sequence we find that gorilla has a trimodular RCCX cluster, versus the reference human bimodular cluster, and additional copies of Class I (pseudo)genes between Gogo-K and Gogo-A (the orthologues of HLA-K and -A). We also find that Gogo-H (and Patr-H) is coding versus the HLA-H pseudogene and, conversely, there is a Gogo-DQB2 pseudogene versus the HLA-DQB2 coding gene. Our analysis, which is freely available through the VEGA genome browser, provides the research community with a comprehensive dataset for comparative and evolutionary research of the MHC.

  19. ARC Code TI: sequenceMiner

    Data.gov (United States)

    National Aeronautics and Space Administration — The sequenceMiner was developed to address the problem of detecting and describing anomalies in large sets of high-dimensional symbol sequences. sequenceMiner works...

  20. Modeling the Near-Infrared Luminosity Function of Young Stellar Clusters

    Science.gov (United States)

    Muench, A. A.; Lada, E. A.; Lada, C. J.

    1999-12-01

    We present the results of numerical experiments designed to evaluate the usefulness of near-infrared luminosity functions for constraining the Initial Mass Function (IMF) of young (0-10 Myr) stellar populations. Using Monte Carlo techniques, we create a suite of model luminosity functions systematically varying each of these basic underlying relations: the underlying IMF, cluster star forming history, and theoretical pre-main sequence mass-to-luminosity relations. Our modeling techniques also allow us to explore the effects of unresolved binaries, infrared excess emission from circumstellar disks, and interstellar extinction on the cluster luminosity function. From this numerical modeling, we find that the luminosity function of a young stellar population is considerably more sensitive to variations in the underlying initial mass function than to either variations in the star forming history or assumed pre-main-sequence (PMS) mass-to-luminosity relation. To illustrate the potential effectiveness of using the KLF of a young cluster to constrain its IMF, we model the observed K band luminosity function of the nearby Trapezium cluster. Our derived mass function for the Trapezium spans two orders of magnitude in stellar mass (5>Msun>0.02) and has a peak near the hydrogen burning limit. Below the hydrogen burning limit, the mass function steadily decreases with decreasing mass throughout the brown dwarf regime. We also test the hypothesis of a space varying IMF by performing model fits to the K band luminosity functions of several other young clusters.

  1. Sequencing Needs for Viral Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Gardner, S N; Lam, M; Mulakken, N J; Torres, C L; Smith, J R; Slezak, T

    2004-01-26

    We built a system to guide decisions regarding the amount of genomic sequencing required to develop diagnostic DNA signatures, which are short sequences that are sufficient to uniquely identify a viral species. We used our existing DNA diagnostic signature prediction pipeline, which selects regions of a target species genome that are conserved among strains of the target (for reliability, to prevent false negatives) and unique relative to other species (for specificity, to avoid false positives). We performed simulations, based on existing sequence data, to assess the number of genome sequences of a target species and of close phylogenetic relatives (''near neighbors'') that are required to predict diagnostic signature regions that are conserved among strains of the target species and unique relative to other bacterial and viral species. For DNA viruses such as variola (smallpox), three target genomes provide sufficient guidance for selecting species-wide signatures. Three near neighbor genomes are critical for species specificity. In contrast, most RNA viruses require four target genomes and no near neighbor genomes, since lack of conservation among strains is more limiting than uniqueness. SARS and Ebola Zaire are exceptional, as additional target genomes currently do not improve predictions, but near neighbor sequences are urgently needed. Our results also indicate that double stranded DNA viruses are more conserved among strains than are RNA viruses, since in most cases there was at least one conserved signature candidate for the DNA viruses and zero conserved signature candidates for the RNA viruses.

  2. Sequence-dependent nucleosome positioning.

    Science.gov (United States)

    Chung, Ho-Ryun; Vingron, Martin

    2009-03-13

    Eukaryotic DNA is organized into a macromolecular structure called chromatin. The basic repeating unit of chromatin is the nucleosome, which consists of two copies of each of the four core histones and DNA. The nucleosomal organization and the positions of nucleosomes have profound effects on all DNA-dependent processes. Understanding the factors that influence nucleosome positioning is therefore of general interest. Among the many determinants of nucleosome positioning, the DNA sequence has been proposed to have a major role. Here, we analyzed more than 860,000 nucleosomal DNA sequences to identify sequence features that guide the formation of nucleosomes in vivo. We found that both a periodic enrichment of AT base pairs and an out-of-phase oscillating enrichment of GC base pairs as well as the overall preference for GC base pairs are determinants of nucleosome positioning. The preference for GC pairs can be related to a lower energetic cost required for deformation of the DNA to wrap around the histones. In line with this idea, we found that only incorporation of both signal components into a sequence model for nucleosome formation results in maximal predictive performance on a genome-wide scale. In this manner, one achieves greater predictive power than published approaches. Our results confirm the hypothesis that the DNA sequence has a major role in nucleosome positioning in vivo.

  3. Explaining the harmonic sequence paradox.

    Science.gov (United States)

    Schmidt, Ulrich; Zimper, Alexander

    2012-05-01

    According to the harmonic sequence paradox, an expected utility decision maker's willingness to pay for a gamble whose expected payoffs evolve according to the harmonic series is finite if and only if his marginal utility of additional income becomes zero for rather low payoff levels. Since the assumption of zero marginal utility is implausible for finite payoff levels, expected utility theory - as well as its standard generalizations such as cumulative prospect theory - are apparently unable to explain a finite willingness to pay. This paper presents first an experimental study of the harmonic sequence paradox. Additionally, it demonstrates that the theoretical argument of the harmonic sequence paradox only applies to time-patient decision makers, whereas the paradox is easily avoided if time-impatience is introduced.

  4. Transgressive Surface as Sequence Boundary

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Analysis of the four cases of the sequence boundary (SB)-transgressive surface (TS) relation in nature shows that applying transgressive surfaces as sequence boundaries has the following merits: it improves the methodology of stratigraphic subdivision; the position of transgressive surface in a sea level curve is relatively fixed; the transgressive surface is a transforming surface of the stratal structure; in platforms or ramps, the transgressive surface is the only choice for determining the sequence boundary; the transgressive surface is a readily recognized physical surface reflected by seismic records in seismostratigraphy. The paper reaches a conclusion that to delineate a SB in terms of the TS is theoretically and practically better than to delineate it between highstand and lowstand sediments as has been done traditionally.

  5. On the base sequence conjecture

    CERN Document Server

    Djokovic, Dragomir Z

    2010-01-01

    Let BS(m,n) denote the set of base sequences (A;B;C;D), with A and B of length m and C and D of length n. The base sequence conjecture (BSC) asserts that BS(n+1,n) exist (i.e., are non-empty) for all n. This is known to be true for n <= 36 and when n is a Golay number. We show that it is also true for n=37 and n=38. It is worth pointing out that BSC is stronger than the famous Hadamard matrix conjecture. In order to demonstrate the abundance of base sequences, we have previously attached to BS(n+1,n) a graph Gamma_n and computed the Gamma_n for n <= 27. We now extend these computations and determine the Gamma_n for n=28,...,35. We also propose a conjecture describing these graphs in general.

  6. Comparative analysis of sequences from PT 2013

    DEFF Research Database (Denmark)

    Mikkelsen, Susie Sommer

    . All but one sequence mapped to the MCP gene while the last sequence mapped to the Neurofilament gene. Approx. half of the sequences contained no errors while the rest differed with 88-99 percent similarity with most having 99% similarity. One sequence, when BLASTed, showed most similarity to European...... Sheatfish and not EHNV. Generally, mistakes occurred at the ends of the sequences. This can be due to several factors. One is that the sequence has not been trimmed of the sequence primer sites. Another is the lack of quality control of the chromatogram. Finally, sequencing in just one direction can result...

  7. Sequence Patterns of Identity Authentication Protocols

    Institute of Scientific and Technical Information of China (English)

    Tao Hongcai; He Dake

    2006-01-01

    From the viewpoint of protocol sequence, analyses are made of the sequence patterns of possible identity authentication protocol under two cases: with or without the trusted third party (TTP). Ten feasible sequence patterns of authentication protocol with TTP and 5 sequence patterns without TTP are gained. These gained sequence patterns meet the requirements for identity authentication,and basically cover almost all the authentication protocols with TTP and without TTP at present. All of the sequence patterns gained are classified into unilateral or bilateral authentication. Then , according to the sequence symmetry, several good sequence patterns with TTP are evaluated. The accompolished results can provide a reference to design of new identity authentication protocols.

  8. KERNEL WORDS AND GAP SEQUENCE OF THE TRIBONACCI SEQUENCE

    Institute of Scientific and Technical Information of China (English)

    Yuke HUANG; Zhiying WEN

    2016-01-01

    In this paper, we investigate the factor properties and gap sequence of the Tri-bonacci sequence, the fixed point of the substitution σ(a, b, c) = (ab, ac, a). Let ωp be the p-th occurrence of ω and Gp(ω) be the gap between ωp and ωp+1. We introduce a notion of kernel for each factor ω, and then give the decomposition of the factor ω with respect to its kernel. Using the kernel and the decomposition, we prove the main result of this paper:for each factorω, the gap sequence{Gp(ω)}p≥1 is the Tribonacci sequence over the alphabet{G1(ω), G2(ω), G4(ω)}, and the expressions of gaps are determined completely. As an appli-cation, for each factorω and p∈N, we determine the position ofωp. Finally we introduce a notion of spectrum for studying some typical combinatorial properties, such as power, overlap and separate of factors.

  9. Sequences and series involving the sequence of composite numbers

    Directory of Open Access Journals (Sweden)

    Panayiotis Vlamos

    2002-01-01

    Full Text Available Denoting by pn and cn the nth prime number and the nth composite number, respectively, we prove that both the sequence (xnn≥1, defined by xn=∑k=1n (ck+1−ck / k−pn / n, and the series ∑n=1∞ (pcn−cpn / npn are convergent.

  10. Integrated sequence analysis. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, K.; Pyy, P

    1998-02-01

    The NKS/RAK subprojet 3 `integrated sequence analysis` (ISA) was formulated with the overall objective to develop and to test integrated methodologies in order to evaluate event sequences with significant human action contribution. The term `methodology` denotes not only technical tools but also methods for integration of different scientific disciplines. In this report, we first discuss the background of ISA and the surveys made to map methods in different application fields, such as man machine system simulation software, human reliability analysis (HRA) and expert judgement. Specific event sequences were, after the surveys, selected for application and testing of a number of ISA methods. The event sequences discussed in the report were cold overpressure of BWR, shutdown LOCA of BWR, steam generator tube rupture of a PWR and BWR disturbed signal view in the control room after an external event. Different teams analysed these sequences by using different ISA and HRA methods. Two kinds of results were obtained from the ISA project: sequence specific and more general findings. The sequence specific results are discussed together with each sequence description. The general lessons are discussed under a separate chapter by using comparisons of different case studies. These lessons include areas ranging from plant safety management (design, procedures, instrumentation, operations, maintenance and safety practices) to methodological findings (ISA methodology, PSA,HRA, physical analyses, behavioural analyses and uncertainty assessment). Finally follows a discussion about the project and conclusions are presented. An interdisciplinary study of complex phenomena is a natural way to produce valuable and innovative results. This project came up with structured ways to perform ISA and managed to apply the in practice. The project also highlighted some areas where more work is needed. In the HRA work, development is required for the use of simulators and expert judgement as

  11. Network motifs in music sequences

    CERN Document Server

    Zanette, Damian H

    2010-01-01

    In this note, I summarize ongoing research on motif distribution in networks built up out of symbolic sequences of Western musical origin. Their motif significance profiles exhibit remarkable consistency over different styles and periods, and define a class that cannot be identified with any of the four "superfamilies" to which most real networks seem to belong. Networks from music sequences possess an unusual abundance of bidirectional connections, due to the inherent reversibility of short musical note patterns. This property contributes to motif significance from both local and large-scale features of musical structure.

  12. Convergence of Fuzzy Set Sequences

    Institute of Scientific and Technical Information of China (English)

    FENG Yu-hu

    2002-01-01

    There are more than one mode of convergence with respect to the fuzzy set sequences. In this paper,common six modes of convergence and their relationships are discussed. These six modes are convergence in uniform metric D, convergence in separable metric Dp or D*p, 1 ≤ p <∞, convergence in level set, strong convergence in level set and weak convergence. Suitable counterexamples are given. The necessary and sufficient conditions of convergence in uniform metric D are described. Some comme nts on the convergence of LRfuzzy number sequences are represented.

  13. DNA Sequencing Using capillary Electrophoresis

    Energy Technology Data Exchange (ETDEWEB)

    Dr. Barry Karger

    2011-05-09

    The overall goal of this program was to develop capillary electrophoresis as the tool to be used to sequence for the first time the Human Genome. Our program was part of the Human Genome Project. In this work, we were highly successful and the replaceable polymer we developed, linear polyacrylamide, was used by the DOE sequencing lab in California to sequence a significant portion of the human genome using the MegaBase multiple capillary array electrophoresis instrument. In this final report, we summarize our efforts and success. We began our work by separating by capillary electrophoresis double strand oligonucleotides using cross-linked polyacrylamide gels in fused silica capillaries. This work showed the potential of the methodology. However, preparation of such cross-linked gel capillaries was difficult with poor reproducibility, and even more important, the columns were not very stable. We improved stability by using non-cross linked linear polyacrylamide. Here, the entangled linear chains could move when osmotic pressure (e.g. sample injection) was imposed on the polymer matrix. This relaxation of the polymer dissipated the stress in the column. Our next advance was to use significantly lower concentrations of the linear polyacrylamide that the polymer could be automatically blown out after each run and replaced with fresh linear polymer solution. In this way, a new column was available for each analytical run. Finally, while testing many linear polymers, we selected linear polyacrylamide as the best matrix as it was the most hydrophilic polymer available. Under our DOE program, we demonstrated initially the success of the linear polyacrylamide to separate double strand DNA. We note that the method is used even today to assay purity of double stranded DNA fragments. Our focus, of course, was on the separation of single stranded DNA for sequencing purposes. In one paper, we demonstrated the success of our approach in sequencing up to 500 bases. Other

  14. The origin of biased sequence depth in sequence-independent nucleic acid amplification and optimization for efficient massive parallel sequencing.

    Directory of Open Access Journals (Sweden)

    Toon Rosseel

    Full Text Available Sequence Independent Single Primer Amplification is one of the most widely used random amplification approaches in virology for sequencing template preparation. This technique relies on oligonucleotides consisting of a 3' random part used to prime complementary DNA synthesis and a 5' defined tag sequence for subsequent amplification. Recently, this amplification method was combined with next generation sequencing to obtain viral sequences. However, these studies showed a biased distribution of the resulting sequence reads over the analyzed genomes. The aim of this study was to elucidate the mechanisms that lead to biased sequence depth when using random amplification. Avian paramyxovirus type 8 was used as a model RNA virus to investigate these mechanisms. We showed, based on in silico analysis of the sequence depth in relation to GC-content, predicted RNA secondary structure and sequence complementarity to the 3' part of the tag sequence, that the tag sequence has the main contribution to the observed bias in sequence depth. We confirmed this finding experimentally using both fragmented and non-fragmented viral RNAs as well as primers differing in random oligomer length (6 or 12 nucleotides and in the sequence of the amplification tag. The observed oligonucleotide annealing bias can be reduced by extending the random oligomer sequence and by in silico combining sequence data from SISPA experiments using different 5' defined tag sequences. These findings contribute to the optimization of random nucleic acid amplification protocols that are currently required for downstream applications such as viral metagenomics and microarray analysis.

  15. Sequences in language and text

    CERN Document Server

    Mikros, George K

    2015-01-01

    The aim of this volume is to present the diverse but highly interesting area of the quantitative analysis of the sequence of various linguistic structures. The collected articles present a wide spectrum of quantitative analyses of linguistic syntagmatic structures and explore novel sequential linguistic entities. This volume will be interesting to all researchers studying linguistics using quantitative methods.

  16. Instruction Sequences for Computer Science

    NARCIS (Netherlands)

    Bergstra, J.A.; Middelburg, C.A.

    2012-01-01

    This book demonstrates that the concept of an instruction sequence offers a novel and useful viewpoint on issues relating to diverse subjects in computer science. Selected issues relating to well-known subjects from the theory of computation and the area of computer architecture are rigorously

  17. Single-primer fluorescent sequencing

    Energy Technology Data Exchange (ETDEWEB)

    Ruth, J.L.; Morgan, C.A.; Middendorf, L.R.; Grone, D.L.; Brumbaugh, J.A.

    1987-05-01

    Modified linker arm oligonucleotides complementary to standard M13 priming sites were synthesized, labelled with either one, two, or three fluoresceins, and purified by reverse-phase HPLC. When used as primers in standard dideoxy M13 sequencing with /sup 32/P-dNTPs, normal autoradiographic patterns were obtained. To eliminate the radioactivity, direct on-line fluorescence detection was achieved by the use of a scanning 10 mW Argon laser emitting 488 nm light. Fluorescent bands were detected directly in standard 0.2 or 0.35 mm thick polyacrylamide gels at a distance of 24 cm from the loading wells by a photomultiplier tube filtered at 520 nm. Horizontal and temporal location of each band was displayed by computer as a band in real time, providing visual appearance similar to normal 4-lane autoradiograms. Using a single primer labelled with two fluoresceins, sequences of between 500 and 600 bases have been read in a single loading with better than 98% accuracy; up to 400 bases can be read reproducibly with no errors. More than 50 sequences have been determined by this method. This approach requires only 1-2 ug of cloned template, and produces continuous sequence data at about one band per minute.

  18. Multifractal analyses of music sequences

    Science.gov (United States)

    Su, Zhi-Yuan; Wu, Tzuyin

    2006-09-01

    Multifractal analysis is applied to study the fractal property of music. In this paper, a method is proposed to transform both the melody and rhythm of a music piece into individual sets of distributed points along a one-dimensional line. The structure of the musical composition is thus manifested and characterized by the local clustering pattern of these sequences of points. Specifically, the local Hölder exponent and the multifractal spectrum are calculated for the transformed music sequences according to the multifractal formalism. The observed fluctuations of the Hölder exponent along the music sequences confirm the non-uniformity feature in the structures of melodic and rhythmic motions of music. Our present result suggests that the shape and opening width of the multifractal spectrum plot can be used to distinguish different styles of music. In addition, a characteristic curve is constructed by mapping the point sequences converted from the melody and rhythm of a musical work into a two-dimensional graph. Each different pieces of music has its own unique characteristic curve. This characteristic curve, which also exhibits a fractal trait, unveils the intrinsic structure of music.

  19. Fractals in DNA sequence analysis

    Institute of Scientific and Technical Information of China (English)

    Yu Zu-Guo(喻祖国); Vo Anh; Gong Zhi-Min(龚志民); Long Shun-Chao(龙顺潮)

    2002-01-01

    Fractal methods have been successfully used to study many problems in physics, mathematics, engineering, finance,and even in biology. There has been an increasing interest in unravelling the mysteries of DNA; for example, how can we distinguish coding and noncoding sequences, and the problems of classification and evolution relationship of organisms are key problems in bioinformatics. Although much research has been carried out by taking into consideration the long-range correlations in DNA sequences, and the global fractal dimension has been used in these works by other people, the models and methods are somewhat rough and the results are not satisfactory. In recent years, our group has introduced a time series model (statistical point of view) and a visual representation (geometrical point of view)to DNA sequence analysis. We have also used fractal dimension, correlation dimension, the Hurst exponent and the dimension spectrum (multifractal analysis) to discuss problems in this field. In this paper, we introduce these fractal models and methods and the results of DNA sequence analysis.

  20. Farey Sequences and Resistor Networks

    Indian Academy of Sciences (India)

    Sameen Ahmed Khan

    2012-05-01

    In this article, we employ the Farey sequence and Fibonacci numbers to establish strict upper and lower bounds for the order of the set of equivalent resistances for a circuit constructed from equal resistors combined in series and in parallel. The method is applicable for networks involving bridge and non-planar circuits.

  1. Sequential Star Formation in RCW 34: A Spectroscopic Census of the Stellar Content of High-mass Star-forming Regions

    CERN Document Server

    Bik, A; Waters, L B F M; Horrobin, M; Henning, Th; Vasyunina, T; Beuther, H; Linz, H; Kaper, L; Ancker, M van den; Lenorzer, A; Churchwell, E; Kurtz, S; Kouwenhoven, M B N; Stolte, A; de Koter, A; Thi, W- F; Comeron, F; Waelkens, Ch

    2010-01-01

    We present VLT/SINFONI integral field spectroscopy of RCW 34 along with Spitzer/IRAC photometry of the surroundings. RCW 34 consists of three different regions. A large bubble has been detected on the IRAC images in which a cluster of intermediate- and low-mass class II objects is found. At the northern edge of this bubble, an HII region is located, ionized by 3 OB stars. Intermediate mass stars (2 - 3 Msun) are detected of G- and K- spectral type. These stars are still in the pre-main sequence (PMS) phase. North of the HII region, a photon-dominated region is present, marking the edge of a dense molecular cloud traced by H2 emission. Several class 0/I objects are associated with this cloud, indicating that star formation is still taking place. The distance to RCW 34 is revised to 2.5 +- 0.2 kpc and an age estimate of 2 - 1 Myrs is derived from the properties of the PMS stars inside the HII region. The most likely scenario for the formation of the three regions is that star formation propagates from South to ...

  2. Chandra observation of an unusually long and intense X-ray flare from a young solar-like star in M78

    CERN Document Server

    Grosso, N; Feigelson, E D; Forbes, T G

    2004-01-01

    LkHA312 has been observed serendipitously with the ACIS-I detector on board Chandra with 26h continuous exposure. This H_alpha emission line star belongs to the star-forming region M78 (NGC2068). From the optical and NIR data, we show that it is a pre-main sequence (PMS) low-mass star with a weak NIR excess. This genuine T Tauri star displayed an X-ray flare with an unusual long rise phase (~8h). The X-ray emission was nearly constant during the first 18h of the observation, and then increased by a factor of 13 during a fast rise phase (~2h), and reached a factor of 16 above the quiescent X-ray level at the end of a gradual phase (~6h) showing a slower rise. To our knowledge this flare, with \\~0.4-~0.5 cts/s, has the highest count rate observed so far with Chandra from a PMS low-mass star. By chance, the source position, 8.2' off-axis, protected this observation from pile-up. We make a spectral analysis of the X-ray emission versus time, showing that the plasma temperature of the quiescent phase and the flare...

  3. Stellar clusterings around "Isolated" Massive YSOs in the LMC

    CERN Document Server

    Stephens, Ian W; Looney, Leslie W; Gruendl, Robert A; Chu, You-Hua; Weisz, Daniel R; Seale, Jonathan P; Chen, C -H Rosie; Wong, Tony; Hughes, Annie; Pineda, Jorge L; Ott, Jürgen; Muller, Erik

    2016-01-01

    Observations suggest that there is a significant fraction of O-stars in the field of the Milky Way that appear to have formed in isolation or in low mass clusters ($$8 $M_\\odot$) young stellar objects (MYSOs) in the Large Magellanic Cloud (LMC). The observations show that while these MYSOs are remote from other MYSOs, OB associations, and even from known giant molecular clouds, they are actually not isolated at all. Imaging reveals $\\sim$100 to several hundred pre--main-sequence (PMS) stars in the vicinity of each MYSO. These previously undetected PMS stars form prominent compact clusters around the MYSOs, and in most cases they are also distributed sparsely across the observed regions. Contrary to what previous high-mass field star studies show, these observations suggest that high-mass stars may not be able to form in clusters with masses less than 100 $M_\\odot$. If these MYSOs are indeed the best candidates for isolated high-mass star formation, then the lack of isolation is at odds with random sampling of...

  4. The young population of the Chamaeleon II dark cloud

    CERN Document Server

    Spezzi, Loredana; Covino, Elvira; Frasca, Antonio; Gandolfi, Davide; Oliveira, Isa; Chapman, Nicholas; Evans, Neal J; Huard, Tracy L; Jørgensen, Jes K; Merín, Bruno; Stapelfeldt, Karl R

    2008-01-01

    We discuss the results of the optical spectroscopic follow-up of pre-main sequence (PMS) objects and candidates selected in the Chamaeleon II dark cloud based on data from the Spitzer Legacy survey "From Molecular Cores to Planet Forming Disks" (c2d) and from previous surveys. Our sample includes both objects with infrared excess selected according to c2d criteria and referred to as Young Stellar Objects and other cloud members and candidates selected from complementary optical and near-infrared data. We characterize the sample of objects by deriving their physical parameters. The vast majority of objects have masses < 1 solar mass and ages < 6 Myr. Several of the PMS objects and candidates lie very close to or below the Hydrogen-burning limit. A first estimate of the slope of the Initial Mass Function in Cha II is consistent with that of other T associations. The star formation efficiency in the cloud (1-4%) is consistent with our own estimates for Taurus and Lupus, but significantly lower than for Cha...

  5. Protoplanetary Disk Evolution around the Triggered Star Forming Region Cepheus B

    CERN Document Server

    Getman, Konstantin V; Luhman, Kevin L; Sicilia-Aguilar, Aurora; Wang, Junfeng; Garmire, Gordon P

    2009-01-01

    The Cepheus B (CepB) molecular cloud and a portion of the nearby CepOB3b OB association, one of the most active regions of star formation within 1 kpc, have been observed with the IRAC detector on board the Spitzer Space Telescope. The goals are to study protoplanetary disk evolution and processes of sequential triggered star formation in the region. Out of ~400 pre-main sequence (PMS) stars selected with an earlier Chandra X-ray Observatory observation, 95% are identified with mid-infrared sources and most of these are classified as diskless or disk-bearing stars. The discovery of the additional >200 IR-excess low-mass members gives a combined Chandra+Spitzer PMS sample complete down to 0.5 Mo outside of the cloud, and somewhat above 1 Mo in the cloud. Analyses of the nearly disk-unbiased combined Chandra+Spitzer selected stellar sample give several results. Our major finding is a spatio-temporal gradient of young stars from the hot molecular core towards the primary ionizing O star HD 217086. This strongly ...

  6. Accretion discs as regulators of stellar angular momentum evolution in the ONC and Taurus-Auriga

    CERN Document Server

    Davies, Claire L; Greaves, Jane S

    2014-01-01

    In light of recent substantial updates to spectral type estimations and newly established intrinsic colours, effective temperatures, and bolometric corrections for pre-main sequence (PMS) stars, we re-address the theory of accretion-disc regulated stellar angular momentum (AM) evolution. We report on the compilation of a consistent sample of fully convective stars within two of the most well-studied and youngest, nearby regions of star formation: the Orion Nebula Cluster (ONC) and Taurus-Auriga. We calculate the average specific stellar AM ($j_{\\star}$) assuming solid body rotation, using surface rotation periods gathered from the literature and new estimates of stellar radii and ages. We use published Spitzer IRAC fluxes to classify our stars as Class II or Class III and compare their $j_{\\star}$ evolution. Our results suggest that disc dispersal is a rapid process that occurs at a variety of ages. We find a consistent $j_{\\star}$ reduction rate between the Class II and Class III PMS stars which we interpret...

  7. The Masses of Transition Circumstellar Disks: Observational Support for Photoevaporation Models

    CERN Document Server

    Cieza, Lucas A; Mathews, Geoffrey S; Williams, Jonathan P

    2008-01-01

    We report deep Sub-Millimeter Array observations of 26 pre-main-sequence (PMS) stars with evolved inner disks. These observations measure the mass of the outer disk (r ~20-100 AU) across every stage of the dissipation of the inner disk (r < 10 AU) as determined by the IR spectral energy distributions (SEDs). We find that only targets with high mid-IR excesses are detected and have disk masses in the 1-5 M_Jup range, while most of our objects remain undetected to sensitivity levels of M_DISK ~0.2-1.5 M_Jup. To put these results in a more general context, we collected publicly available data to construct the optical to millimeter wavelength SEDs of over 120 additional PMS stars. We find that the near-IR and mid-IR emission remain optically thick in objects whose disk masses span 2 orders of magnitude (~0.5-50 M_Jup). Taken together, these results imply that, in general, inner disks start to dissipate only after the outer disk has been significantly depleted of mass. This provides strong support for photoevap...

  8. AN UPDATED {sup 6}Li(p, {alpha}){sup 3}He REACTION RATE AT ASTROPHYSICAL ENERGIES WITH THE TROJAN HORSE METHOD

    Energy Technology Data Exchange (ETDEWEB)

    Lamia, L.; Spitaleri, C.; Sergi, M. L. [Dipartimento di Fisica e Astronomia, Universita di Catania, I-95123 Catania (Italy); Pizzone, R. G.; Tumino, A.; La Cognata, M. [INFN-Laboratori Nazionali del Sud, I-95125 Catania (Italy); Tognelli, E.; Degl' Innocenti, S.; Prada Moroni, P. G. [Dipartimento di Fisica, Universita di Pisa, I-56127 Pisa (Italy); Pappalardo, L. [Dipartimento di Fisica e Scienze della Terra, Universita di Ferrara, I-44100 Ferrara (Italy)

    2013-05-01

    The lithium problem influencing primordial and stellar nucleosynthesis is one of the most interesting unsolved issues in astrophysics. {sup 6}Li is the most fragile of lithium's stable isotopes and is largely destroyed in most stars during the pre-main-sequence (PMS) phase. For these stars, the convective envelope easily reaches, at least at its bottom, the relatively low {sup 6}Li ignition temperature. Thus, gaining an understanding of {sup 6}Li depletion also gives hints about the extent of convective regions. For this reason, charged-particle-induced reactions in lithium have been the subject of several studies. Low-energy extrapolations of these studies provide information about both the zero-energy astrophysical S(E) factor and the electron screening potential, U{sub e} . Thanks to recent direct measurements, new estimates of the {sup 6}Li(p, {alpha}){sup 3}He bare-nucleus S(E) factor and the corresponding U{sub e} value have been obtained by applying the Trojan Horse method to the {sup 2}H({sup 6}Li, {alpha} {sup 3}He)n reaction in quasi-free kinematics. The calculated reaction rate covers the temperature window 0.01 to 2T{sub 9} and its impact on the surface lithium depletion in PMS models with different masses and metallicities has been evaluated in detail by adopting an updated version of the FRANEC evolutionary code.

  9. Radio detection of the young binary HD 160934

    Science.gov (United States)

    Azulay, R.; Guirado, J. C.; Marcaide, J. M.; Martí-Vidal, I.; Arroyo-Torres, B.

    2014-01-01

    Context. Precise determination of dynamical masses of pre-main-sequence (PMS) stars is essential to calibrate stellar evolution models that are widely used to derive theoretical masses of young low-mass objects. Binary stars in young, nearby loose associations are particularly good candidates for this calibration since all members share a common age. Interestingly, some of these young binaries present a persistent and compact radio emission, which makes them excellent targets for astrometric VLBI studies. Aims: We aim to monitor the orbital motion of the binary system HD 160934, a member of the AB Doradus moving group. Methods: We observed HD 160934 with the Very Large Array and the European VLBI Network at 8.4 and 5 GHz, respectively. The orbital information derived from these observations was analyzed along with previously reported orbital measurements. Results: We show that the two components of the binary, HD 160934 A and HD 160934 c, display compact radio emission at VLBI scales, providing precise information on the relative orbit. Revised orbital elements were estimated. Conclusions: Future VLBI monitoring of this pair should determine precise model-independent mass estimates for the A and c components, which will serve as calibration tests for PMS evolutionary models.

  10. Spectroscopic monitoring of the Herbig Ae star HD 104237. II. Non-radial pulsations, mode analysis and fundamental stellar parameters

    CERN Document Server

    Fumel, Aurelie

    2011-01-01

    Herbig Ae/Be stars are intermediate-mass pre-main sequence (PMS) stars showing signs of intense activity and strong stellar winds, whose origin is not yet understood in the frame of current theoretical models of stellar evolution for young stars. The evolutionary tracks of the earlier Herbig Ae stars cross a recently discovered PMS instability strip. Many of these stars exhibit pulsations of delta Scuti type. HD 104237 is a well-known pulsating Herbig Ae star. In this article, we reinvestigated an extensive high-resolution quasi-continuous spectroscopic data set in order to search for very faint indications of non-radial pulsations in the line profile. To do this, we worked on dynamical spectra of equivalent photospheric (LSD) profiles of HD 104237. A 2D Fourier analysis (F2D) was performed of the entire profile and the temporal variation of the central depth of the line was studied with the time-series analysis tools Period04 and SigSpec. We present a mode identification corresponding to the detected dominan...

  11. Protoplanetary disk shadowing by gas infalling onto the young star AK Sco

    CERN Document Server

    de Castro, Ana I Gomez; France, Kevin; Sytov, Alexey; Bisikalo, Dmitry

    2016-01-01

    Young solar-type stars grow through the accretion of material from the circumstellar disk during pre-main sequence (PMS) evolution. The ultraviolet radiation generated in this process plays a key role in the chemistry and evolution of young planetary disks. In particular, the hydrogen Lyman-alpha line (Lya) etches the disk surface by driving photoevaporative flows that control disk evolution. Using the Hubble Space Telescope, we have monitored the PMS binary star AK Sco during the periastron passage and have detected a drop of the H2 flux by up to 10% lasting 5.9 hours. We show that the decrease of the H2 flux can be produced by the occultation of the stellar Lya photons by a gas stream in free fall from 3 R*. Given the high optical depth of the Lya line, a very low gas column of NH > 5e17 cm-2 suffices to block the Lya radiation without producing noticeable effects in the rest of the stellar spectral tracers.

  12. Formation scenarios for the young stellar associations between galactic longitudes l = 280-360 deg

    CERN Document Server

    Sartori, M J; Dias, W S; Sartori, Marilia J.; Lepine, Jacques R. D.; Dias, Wilton S.

    2003-01-01

    We investigate the spatial distribution, the space velocities and age distribution of the pre-main sequence (PMS) stars belonging to Ophiuchus, Lupus and Chamaeleon star-forming regions (SFRs), and of the young early-type star members of the Scorpius-Centaurus OB association. These young stellar associations extend over the galactic longitude range from 280 deg. to 360 deg., and are at a distance interval of around 100 and 200 pc. The study is based on a compilation of distances, proper motions and radial velocities from the literature for the kinematic properties, and of basic stellar data for the construction of Hertzsprung-Russel diagrams. Although there was no well-known OB association in Chamaeleon, the distances and the proper motions of a group of 21 B- and A-type stars, taken from the Hipparcos Catalogue, lead us to propose that they form a young association. We show that the young early-type stars of the OB associations and the PMS stars of the SFRs follow a similar spatial distribution, i.e., there ...

  13. Optical polarimetry of star-forming regions

    Energy Technology Data Exchange (ETDEWEB)

    Gledhill, T.M.

    1987-01-01

    The polarimetric investigation of nebulosity associated with loss-mass pre-main sequence (PMS) stellar objects is detailed. Three regions of on-going star formation are considered, specifically, the Haro 6-5 and the HL/XZ Tau systems - both associated with dark clouds in the Taurus complex - and the PV Cephei nebulosity near NGC7023. In each region the imaging observations suggest bipolarity in the optical structure of the nebulosity, and the polarimetric data are used to determine the locations of the illuminating sources. Evidence is found for the association of circumstellar discs of obscuration with the PMS objects Haro 6-5A (FS Tau), Haro 6-5B, HL Tau, and PV Cephei. In each case the polarimetric data suggest that the local magnetic field has played an important role in the evolution of the star and the circumstellar material. Examination of the source-region polarization maps suggests that at least one of the objects considered is surrounded by a dust grain-aligning magnetic field with a predominantly toroidal geometry in the plane of the circumstellar disc. Implications for current theories of outflow acceleration and cloud evolution are discussed.

  14. The Toothpick Sequence and Other Sequences from Cellular Automata

    CERN Document Server

    Applegate, David; Sloane, N J A

    2010-01-01

    A two-dimensional arrangement of toothpicks is constructed by the following iterative procedure. At stage 1, place a single toothpick of length 1 on a square grid, aligned with the y-axis. At each subsequent stage, for every exposed toothpick end, place an orthogonal toothpick centered at that end. The resulting structure has a fractal-like appearance. We will analyze the toothpick sequence, which gives the total number of toothpicks after n steps. We also study several related sequences that arise from enumerating active cells in cellular automata. Some unusual recurrences appear: a typical example is that instead of the Fibonacci recurrence, which we may write as a(2+i) = a(i) + a(i+1), we set n = 2^k+i (0 = 0} (1+x^{2^k-1}+2x^{2^k}) and variations thereof.

  15. Algebraic divisibility sequences over function fields

    CERN Document Server

    Ingram, Patrick; Silverman, Joseph H; Stange, Katherine E; Streng, Marco

    2011-01-01

    We study the existence of primes and of primitive divisors in classical divisibility sequences defined over function fields. Under various hypotheses, we prove that Lucas sequences and elliptic divisibility sequences over function fields defined over number fields contain infinitely many irreducible elements. We also prove that an elliptic divisibility sequence over a function field has only finitely many terms lacking a primitive divisor.

  16. Stream cipher based on GSS sequences

    Institute of Scientific and Technical Information of China (English)

    HU Yupu; XIAO Guozhen

    2004-01-01

    Generalized self-shrinking sequences, simply named the GSS sequences,are novel periodic sequences that have many advantages in cryptography. In this paper,we give several results about GSS sequence's application to cryptography. First, we give a simple method for selecting those GSS sequences whose least periods reach the maximum. Second, we give a method for describing and computing the auto-correlation coefficients of GSS sequences. Finally, we point out that some GSS sequences, when used as stream ciphers, have a security weakness.

  17. Pig genome sequence - analysis and publication strategy

    DEFF Research Database (Denmark)

    Archibald, Alan L.; Bolund, Lars; Churcher, Carol;

    2010-01-01

    BACKGROUND: The pig genome is being sequenced and characterised under the auspices of the Swine Genome Sequencing Consortium. The sequencing strategy followed a hybrid approach combining hierarchical shotgun sequencing of BAC clones and whole genome shotgun sequencing. RESULTS: Assemblies......) is under construction and will incorporate whole genome shotgun sequence (WGS) data providing > 30x genome coverage. The WGS sequence, most of which comprise short Illumina/Solexa reads, were generated from DNA from the same single Duroc sow as the source of the BAC library from which clones were...

  18. Sequence-structure relations of biopolymers

    CERN Document Server

    Barrett, Christopher; Reidys, Christian M

    2015-01-01

    Motivation: DNA data is transcribed into single-stranded RNA, which folds into specific molecular structures. In this paper we pose the question to what extent sequence- and structure-information correlate. We view this correlation as structural semantics of sequence data that allows for a different interpretation than conventional sequence alignment. Structural semantics could enable us to identify more general embedded "patterns" in DNA and RNA sequences. Results: We compute the partition function of sequences with respect to a fixed structure and connect this computation to the mutual information of a sequence-structure pair for RNA secondary structures. We present a Boltzmann sampler and obtain the a priori probability of specific sequence patterns. We present a detailed analysis for the three PDB-structures, 2JXV (hairpin), 2N3R (3-branch multi-loop) and 1EHZ (tRNA). We localize specific sequence patterns, contrast the energy spectrum of the Boltzmann sampled sequences versus those sequences that refold ...

  19. Expressing stochastic filters via number sequences

    OpenAIRE

    Capponi, A.; Farina, A; Pilotto, C.

    2010-01-01

    We generalize the results presented in [1] regarding the relation between the Kalman filter and the Fibonacci sequence. We consider more general filtering models and relate the finite dimensional Kalman and Benes filters to the Fibonacci sequence and to the Golden Section. We also prove that Fibonacci numbers may be expressed as the convolution of the Fibonacci and Padovan sequence, thus extending the connection between stochastic filtering and Fibonacci sequence to the Padovan sequence.

  20. Cassini Mission Sequence Subsystem (MSS)

    Science.gov (United States)

    Alland, Robert

    2011-01-01

    This paper describes my work with the Cassini Mission Sequence Subsystem (MSS) team during the summer of 2011. It gives some background on the motivation for this project and describes the expected benefit to the Cassini program. It then introduces the two tasks that I worked on - an automatic system auditing tool and a series of corrections to the Cassini Sequence Generator (SEQ_GEN) - and the specific objectives these tasks were to accomplish. Next, it details the approach I took to meet these objectives and the results of this approach, followed by a discussion of how the outcome of the project compares with my initial expectations. The paper concludes with a summary of my experience working on this project, lists what the next steps are, and acknowledges the help of my Cassini colleagues.

  1. Nonparametric Inference for Periodic Sequences

    KAUST Repository

    Sun, Ying

    2012-02-01

    This article proposes a nonparametric method for estimating the period and values of a periodic sequence when the data are evenly spaced in time. The period is estimated by a "leave-out-one-cycle" version of cross-validation (CV) and complements the periodogram, a widely used tool for period estimation. The CV method is computationally simple and implicitly penalizes multiples of the smallest period, leading to a "virtually" consistent estimator of integer periods. This estimator is investigated both theoretically and by simulation.We also propose a nonparametric test of the null hypothesis that the data have constantmean against the alternative that the sequence of means is periodic. Finally, our methodology is demonstrated on three well-known time series: the sunspots and lynx trapping data, and the El Niño series of sea surface temperatures. © 2012 American Statistical Association and the American Society for Quality.

  2. Genome Sequence of Mycobacteriophage Momo.

    Science.gov (United States)

    Pope, Welkin H; Bina, Elizabeth A; Brahme, Indraneel S; Hill, Amy B; Himmelstein, Philip H; Hunsicker, Sara M; Ish, Amanda R; Le, Tinh S; Martin, Mary M; Moscinski, Catherine N; Shetty, Sameer A; Swierzewski, Tomasz; Iyengar, Varun B; Kim, Hannah; Schafer, Claire E; Grubb, Sarah R; Warner, Marcie H; Bowman, Charles A; Russell, Daniel A; Hatfull, Graham F

    2015-06-18

    Momo is a newly discovered phage of Mycobacterium smegmatis mc(2)155. Momo has a double-stranded DNA genome 154,553 bp in length, with 233 predicted protein-encoding genes, 34 tRNA genes, and one transfer-messenger RNA (tmRNA) gene. Momo has a myoviral morphology and shares extensive nucleotide sequence similarity with subcluster C1 mycobacteriophages. Copyright © 2015 Pope et al.

  3. Multiplicative LSTM for sequence modelling

    OpenAIRE

    Krause, Ben; Lu, Liang; Murray, Iain; Renals, Steve

    2016-01-01

    This paper introduces multiplicative LSTM, a novel hybrid recurrent neural network architecture for sequence modelling that combines the long short-term memory (LSTM) and multiplicative recurrent neural network architectures. Multiplicative LSTM is motivated by its flexibility to have very different recurrent transition functions for each possible input, which we argue helps make it more expressive in autoregressive density estimation. We show empirically that multiplicative LSTM outperforms ...

  4. DISCOVERY OF X-RAY EMISSION FROM YOUNG SUNS IN THE SMALL MAGELLANIC CLOUD

    Energy Technology Data Exchange (ETDEWEB)

    Oskinova, L. M.; Hainich, R. [Institute for Physics and Astronomy, University Potsdam, D-14476 Potsdam (Germany); Sun, W.; Chen, Y. [Department of Astronomy, Nanjing University, Nanjing, 210093 Jiangsu (China); Evans, C. J. [UK Astronomy Technology Centre, Royal Observatory Edinburgh, Blackford Hill, Edinburgh EH9 3HJ (United Kingdom); Henault-Brunet, V. [Scottish Universities Physics Alliance (SUPA), Institute for Astronomy, University of Edinburgh, Blackford Hill, Edinburgh EH9 3HJ (United Kingdom); Chu, Y.-H.; Gruendl, R. A. [Department of Astronomy, University of Illinois, 1002 West Green Street, Urbana, IL 61801 (United States); Gallagher, J. S. III [Department of Astronomy, University of Wisconsin-Madison, 5534 Sterling, 475 North Charter Street, Madison, WI 53706 (United States); Guerrero, M. A. [Instituto de Astrofisica de Andalucia, IAA-CSIC, Glorieta de la Astronomia s/n, E-18008 Granada (Spain); Guedel, M. [Department of Astrophysics, University of Vienna, Tuerkenschanzstrasse 17, A-1180 Vienna (Austria); Silich, S. [Instituto Nacional de Astrofisica Optica y Electronica, AP 51, 72000 Puebla (Mexico); Naze, Y. [GAPHE, Departement AGO, Universite de Liege, Allee du 6 Aout 17, Bat. B5C, B-4000 Liege (Belgium); Reyes-Iturbide, J. [LATO-DCET/Universidade Estadual de Santa Cruz, Rodovia Jorge Amado, km 16, 45662-000 Ilheus, BA (Brazil)

    2013-03-01

    We report the discovery of extended X-ray emission within the young star cluster NGC 602a in the Wing of the Small Magellanic Cloud (SMC) based on observations obtained with the Chandra X-Ray Observatory. X-ray emission is detected from the cluster core area with the highest stellar density and from a dusty ridge surrounding the H II region. We use a census of massive stars in the cluster to demonstrate that a cluster wind or wind-blown bubble is unlikely to provide a significant contribution to the X-ray emission detected from the central area of the cluster. We therefore suggest that X-ray emission at the cluster core originates from an ensemble of low- and solar-mass pre-main-sequence (PMS) stars, each of which would be too weak in X-rays to be detected individually. We attribute the X-ray emission from the dusty ridge to the embedded tight cluster of the newborn stars known in this area from infrared studies. Assuming that the levels of X-ray activity in young stars in the low-metallicity environment of NGC 602a are comparable to their Galactic counterparts, then the detected spatial distribution, spectral properties, and level of X-ray emission are largely consistent with those expected from low- and solar-mass PMS stars and young stellar objects (YSOs). This is the first discovery of X-ray emission attributable to PMS stars and YSOs in the SMC, which suggests that the accretion and dynamo processes in young, low-mass objects in the SMC resemble those in the Galaxy.

  5. New Determination of the 2H(d,p)3H and 2H(d,n)3He Reaction Rates at Astrophysical Energies

    Science.gov (United States)

    Tumino, A.; Spartà, R.; Spitaleri, C.; Mukhamedzhanov, A. M.; Typel, S.; Pizzone, R. G.; Tognelli, E.; Degl'Innocenti, S.; Burjan, V.; Kroha, V.; Hons, Z.; La Cognata, M.; Lamia, L.; Mrazek, J.; Piskor, S.; Prada Moroni, P. G.; Rapisarda, G. G.; Romano, S.; Sergi, M. L.

    2014-04-01

    The cross sections of the 2H(d,p)3H and 2H(d,n)3He reactions have been measured via the Trojan Horse method applied to the quasi-free 2H(3He,p 3H)1H and 2H(3He,n 3He)1H processes at 18 MeV off the proton in 3He. For the first time, the bare nucleus S(E) factors have been determined from 1.5 MeV, across the relevant region for standard Big Bang nucleosynthesis, down to the thermal energies of deuterium burning in the pre-main-sequence (PMS) phase of stellar evolution, as well as of future fusion reactors. Both the energy dependence and the absolute value of the S(E) factors deviate by more than 15% from the available direct data and existing fitting curves, with substantial variations in the electron screening by more than 50%. As a consequence, the reaction rates for astrophysics experience relevant changes, with a maximum increase of up to 20% at the temperatures of the PMS phase. From a recent primordial abundance sensitivity study, it turns out that the 2H(d,n)3He reaction is quite influential on 7Li, and the present change in the reaction rate leads to a decrease in its abundance by up to 10%. The present reaction rates have also been included in an updated version of the FRANEC evolutionary code to analyze their influence on the central deuterium abundance in PMS stars with different masses. The largest variation of about 10%-15% pertains to young stars (=1 M ⊙.

  6. Multineuronal Spike Sequences Repeat with Millisecond Precision

    Directory of Open Access Journals (Sweden)

    Koki eMatsumoto

    2013-06-01

    Full Text Available Cortical microcircuits are nonrandomly wired by neurons. As a natural consequence, spikes emitted by microcircuits are also nonrandomly patterned in time and space. One of the prominent spike organizations is a repetition of fixed patterns of spike series across multiple neurons. However, several questions remain unsolved, including how precisely spike sequences repeat, how the sequences are spatially organized, how many neurons participate in sequences, and how different sequences are functionally linked. To address these questions, we monitored spontaneous spikes of hippocampal CA3 neurons ex vivo using a high-speed functional multineuron calcium imaging technique that allowed us to monitor spikes with millisecond resolution and to record the location of spiking and nonspiking neurons. Multineuronal spike sequences were overrepresented in spontaneous activity compared to the statistical chance level. Approximately 75% of neurons participated in at least one sequence during our observation period. The participants were sparsely dispersed and did not show specific spatial organization. The number of sequences relative to the chance level decreased when larger time frames were used to detect sequences. Thus, sequences were precise at the millisecond level. Sequences often shared common spikes with other sequences; parts of sequences were subsequently relayed by following sequences, generating complex chains of multiple sequences.

  7. Method and apparatus for biological sequence comparison

    Science.gov (United States)

    Marr, T.G.; Chang, W.I.

    1997-12-23

    A method and apparatus are disclosed for comparing biological sequences from a known source of sequences, with a subject (query) sequence. The apparatus takes as input a set of target similarity levels (such as evolutionary distances in units of PAM), and finds all fragments of known sequences that are similar to the subject sequence at each target similarity level, and are long enough to be statistically significant. The invention device filters out fragments from the known sequences that are too short, or have a lower average similarity to the subject sequence than is required by each target similarity level. The subject sequence is then compared only to the remaining known sequences to find the best matches. The filtering member divides the subject sequence into overlapping blocks, each block being sufficiently large to contain a minimum-length alignment from a known sequence. For each block, the filter member compares the block with every possible short fragment in the known sequences and determines a best match for each comparison. The determined set of short fragment best matches for the block provide an upper threshold on alignment values. Regions of a certain length from the known sequences that have a mean alignment value upper threshold greater than a target unit score are concatenated to form a union. The current block is compared to the union and provides an indication of best local alignment with the subject sequence. 5 figs.

  8. Modeling the Near-Infrared Luminosity Functions of Young Stellar Clusters

    Science.gov (United States)

    Muench, August A.; Lada, Elizabeth A.; Lada, Charles J.

    2000-04-01

    We present the results of numerical experiments designed to evaluate the usefulness of near-infrared (NIR) luminosity functions for constraining the initial mass function (IMF) of young stellar populations. We test the sensitivity of the NIR K-band luminosity function (KLF) of a young stellar cluster to variations in the underlying IMF, star-forming history, and pre-main-sequence mass-to-luminosity relations. Using Monte Carlo techniques, we create a suite of model luminosity functions systematically varying each of these basic underlying relations. From this numerical modeling, we find that the luminosity function of a young stellar population is considerably more sensitive to variations in the underlying initial mass function than to either variations in the star-forming history or assumed pre-main-sequence (PMS) mass-to-luminosity relation. Variations in a cluster's star-forming history are also found to produce significant changes in the KLF. In particular, we find that the KLFs of young clusters evolve in a systematic manner with increasing mean age. Our experiments indicate that variations in the PMS mass-to-luminosity relation, resulting from differences in adopted PMS tracks, produce only small effects on the form of the model luminosity functions and that these effects are mostly likely not detectable observationally. To illustrate the potential effectiveness of using the KLF of a young cluster to constrain its IMF, we model the observed KLF of the nearby Trapezium cluster. With knowledge of the star-forming history of this cluster obtained from optical spectroscopic studies, we derive the simplest underlying IMF whose model luminosity function matches the observations. Our derived mass function for the Trapezium spans 2 orders of magnitude in stellar mass (5>Msolar>0.02) and has a peak near the hydrogen-burning limit. Below the hydrogen-burning limit, the mass function steadily decreases with decreasing mass throughout the brown dwarf regime. Comparison

  9. Static multiplicities in heterogeneous azeotropic distillation sequences

    DEFF Research Database (Denmark)

    Esbjerg, Klavs; Andersen, Torben Ravn; Jørgensen, Sten Bay

    1998-01-01

    In this paper the results of a bifurcation analysis on heterogeneous azeotropic distillation sequences are given. Two sequences suitable for ethanol dehydration are compared: The 'direct' and the 'indirect' sequence. It is shown, that the two sequences, despite their similarities, exhibit very...... different static behavior. The method of Petlyuk and Avet'yan (1971), Bekiaris et al. (1993), which assumes infinite reflux and infinite number of stages, is extended to and applied on heterogeneous azeotropic distillation sequences. The predictions are substantiated through simulations. The static sequence...

  10. On Inclusion Relations between Some Sequence Spaces

    Directory of Open Access Journals (Sweden)

    R. Çolak

    2016-01-01

    Full Text Available We determine the relations between the classes S^λ of almost λ-statistically convergent sequences and the relations between the classes V^,λ of strongly almost V,λ-summable sequences for various sequences λ, μ in the class Λ. Furthermore we also give the relations between the classes S^λ of almost λ-statistically convergent sequences and the classes V^,λ of strongly almost V,λ-summable sequences for various sequences λ,μ∈Λ.

  11. Bernoulli measure of complex admissible kneading sequences

    CERN Document Server

    Bruin, Henk

    2012-01-01

    Iterated quadratic polynomials give rise to a rich collection of different dynamical systems that are parametrized by a simple complex parameter $c$. The different dynamical features are encoded by the \\emph{kneading sequence} which is an infinite sequence over $\\{0,\\1\\}$. Not every such sequence actually occurs in complex dynamics. The set of admissible kneading sequences was described by Milnor and Thurston for real quadratic polynomials, and by the authors in the complex case. We prove that the set of admissible kneading sequences has positive Bernoulli measure within the set of sequences over $\\{0,\\1\\}$.

  12. Blind sequence-length estimation of low-SNR cyclostationary sequences

    CSIR Research Space (South Africa)

    Vlok, JD

    2014-06-01

    Full Text Available Several existing direct-sequence spread spectrum (DSSS) detection and estimation algorithms assume prior knowledge of the symbol period or sequence length, although very few sequence-length estimation techniques are available in the literature...

  13. Modified Genetic Algorithm for DNA Sequence Assembly by Shotgun and Hybridization Sequencing Techniques

    Directory of Open Access Journals (Sweden)

    Prof.Narayan Kumar Sahu

    2012-09-01

    Full Text Available Since the advent of rapid DNA sequencing methods in 1976, scientists have had the problem of inferring DNA sequences from sequenced fragments. Shotgun sequencing is a well-established biological and computational method used in practice. Many conventional algorithms for shotgun sequencing are based on the notion of pair wise fragment overlap. While shotgun sequencing infers a DNA sequence given the sequences of overlapping fragments, a recent and complementary method, called sequencing by hybridization (SBH, infers a DNA sequence given the set of oligomers that represents all sub words of some fixed length, k. In this paper, we propose a new computer algorithm for DNA sequence assembly that combines in a novel way the techniques of both shotgun and SBH methods. Based on our preliminary investigations, the algorithm promises- to be very fast and practical for DNA sequence assembly [1].

  14. Biomolecule Sequencer: Nanopore Sequencing Technology for In-Situ Environmental Monitoring and Astrobiology

    Science.gov (United States)

    John, K. K.; Botkin, D. J.; Burton, A. S.; Castro-Wallace, S. L.; Chaput, J. D.; Dworkin, J. P.; Lupisella, M. L.; Mason, C. E.; Rubins, K. H.; Smith, D. J.; Stahl, S.; Switzer, C.

    2016-10-01

    Biomolecule Sequencer will demonstrate, for the first time, that DNA sequencing is feasible as a tool for in-situ environmental monitoring and astrobiology. A space-based sequencer could identify microbes, diseases, and help detect DNA-based life.

  15. Integration of retinal image sequences

    Science.gov (United States)

    Ballerini, Lucia

    1998-10-01

    In this paper a method for noise reduction in ocular fundus image sequences is described. The eye is the only part of the human body where the capillary network can be observed along with the arterial and venous circulation using a non invasive technique. The study of the retinal vessels is very important both for the study of the local pathology (retinal disease) and for the large amount of information it offers on systematic haemodynamics, such as hypertension, arteriosclerosis, and diabetes. In this paper a method for image integration of ocular fundus image sequences is described. The procedure can be divided in two step: registration and fusion. First we describe an automatic alignment algorithm for registration of ocular fundus images. In order to enhance vessel structures, we used a spatially oriented bank of filters designed to match the properties of the objects of interest. To evaluate interframe misalignment we adopted a fast cross-correlation algorithm. The performances of the alignment method have been estimated by simulating shifts between image pairs and by using a cross-validation approach. Then we propose a temporal integration technique of image sequences so as to compute enhanced pictures of the overall capillary network. Image registration is combined with image enhancement by fusing subsequent frames of a same region. To evaluate the attainable results, the signal-to-noise ratio was estimated before and after integration. Experimental results on synthetic images of vessel-like structures with different kind of Gaussian additive noise as well as on real fundus images are reported.

  16. Discrete low-discrepancy sequences

    CERN Document Server

    Angel, Omer; Martin, James B; Propp, James

    2009-01-01

    Holroyd and Propp used Hall's marriage theorem to show that, given a probability distribution pi on a finite set S, there exists an infinite sequence s_1,s_2,... in S such that for all integers k >= 1 and all s in S, the number of i in [1,k] with s_i = s differs from k pi(s) by at most 1. We prove a generalization of this result using a simple explicit algorithm. A special case of this algorithm yields an extension of Holroyd and Propp's result to the case of discrete probability distributions on infinite sets.

  17. Infinite matrices and sequence spaces

    CERN Document Server

    Cooke, Richard G

    2014-01-01

    This clear and correct summation of basic results from a specialized field focuses on the behavior of infinite matrices in general, rather than on properties of special matrices. Three introductory chapters guide students to the manipulation of infinite matrices, covering definitions and preliminary ideas, reciprocals of infinite matrices, and linear equations involving infinite matrices.From the fourth chapter onward, the author treats the application of infinite matrices to the summability of divergent sequences and series from various points of view. Topics include consistency, mutual consi

  18. Differential correlation for sequencing data.

    Science.gov (United States)

    Siska, Charlotte; Kechris, Katerina

    2017-01-19

    Several methods have been developed to identify differential correlation (DC) between pairs of molecular features from -omics studies. Most DC methods have only been tested with microarrays and other platforms producing continuous and Gaussian-like data. Sequencing data is in the form of counts, often modeled with a negative binomial distribution making it difficult to apply standard correlation metrics. We have developed an R package for identifying DC called Discordant which uses mixture models for correlations between features and the Expectation Maximization (EM) algorithm for fitting parameters of the mixture model. Several correlation metrics for sequencing data are provided and tested using simulations. Other extensions in the Discordant package include additional modeling for different types of differential correlation, and faster implementation, using a subsampling routine to reduce run-time and address the assumption of independence between molecular feature pairs. With simulations and breast cancer miRNA-Seq and RNA-Seq data, we find that Spearman's correlation has the best performance among the tested correlation methods for identifying differential correlation. Application of Spearman's correlation in the Discordant method demonstrated the most power in ROC curves and sensitivity/specificity plots, and improved ability to identify experimentally validated breast cancer miRNA. We also considered including additional types of differential correlation, which showed a slight reduction in power due to the additional parameters that need to be estimated, but more versatility in applications. Finally, subsampling within the EM algorithm considerably decreased run-time with negligible effect on performance. A new method and R package called Discordant is presented for identifying differential correlation with sequencing data. Based on comparisons with different correlation metrics, this study suggests Spearman's correlation is appropriate for sequencing data

  19. Asymptotics of Lagged Fibonacci Sequences

    CERN Document Server

    Mertens, Stephan

    2009-01-01

    Consider "lagged" Fibonacci sequences $a(n) = a(n-1)+a(\\lfloor n/k\\rfloor)$ for $k > 1$. We show that $\\lim_{n\\to\\infty} a(kn)/a(n)\\cdot\\ln n/n = k\\ln k$ and we demonstrate the slow numerical convergence to this limit and how to deal with this slow convergence. We also discuss the connection between two classical results of N.G. de Bruijn and K. Mahler on the asymptotics of $a(n)$.

  20. FOGSAA: Fast Optimal Global Sequence Alignment Algorithm

    Science.gov (United States)

    Chakraborty, Angana; Bandyopadhyay, Sanghamitra

    2013-04-01

    In this article we propose a Fast Optimal Global Sequence Alignment Algorithm, FOGSAA, which aligns a pair of nucleotide/protein sequences faster than any optimal global alignment method including the widely used Needleman-Wunsch (NW) algorithm. FOGSAA is applicable for all types of sequences, with any scoring scheme, and with or without affine gap penalty. Compared to NW, FOGSAA achieves a time gain of (70-90)% for highly similar nucleotide sequences (> 80% similarity), and (54-70)% for sequences having (30-80)% similarity. For other sequences, it terminates with an approximate score. For protein sequences, the average time gain is between (25-40)%. Compared to three heuristic global alignment methods, the quality of alignment is improved by about 23%-53%. FOGSAA is, in general, suitable for aligning any two sequences defined over a finite alphabet set, where the quality of the global alignment is of supreme importance.