WorldWideScience

Sample records for possibly 106-108 alternative

  1. Search of the first excited states 0+ of 108Cd and106Cd

    International Nuclear Information System (INIS)

    Roussiere, B.

    1981-01-01

    108 Cd and 106 Cd nuclei have been studied from the β + /EC decay of 108 In and 106 In using the isocele II isotope separator working on-line with the Orsay synchrocyclotron. In order to produce indium nuclei, a molten tin target is irradiated by protons (E = 200 MeV) or 3 He (E = 270 MeV). The comparison of saturation activity measured after mass separation with the one measured before mass-separation has allowed us to determine the average delay-time of indium isotopes and the overall efficiency of the separator. Single γ rays, conversion electrons rays, γ-γ-t and γ-e - -t coincidence measurements have been performed to build level schemes of 108 Cd and 106 Cd. In 108 Cd, the first excited 0 + state has been established unambiguously. This state preferably decays to the 2 2 + and not to the 2 1 + as it does in the even-even neighbouring Cd nuclei. An excited 0 + state is proposed in 106 Cd. These states could not be interpreted as headstate of collective band corresponding to a shape different from the ground state one. On the other hand, the model of G. Alaga (vibrator + two proton holes), as well as the IBA2 F. Iachello one seem to be able to describe the low-lying states properties. Finally, the feeding balance and the deduced log ft values have led us to discuss the possible values of the 108 In and 106 In isomeric state spins [fr

  2. Coulomb excitation of the odd-odd isotopes {sup 106,108}In

    Energy Technology Data Exchange (ETDEWEB)

    Ekstroem, A.; Fahlander, C. [University of Lund, Physics Department, Box 118, Lund (Sweden); Cederkaell, J. [University of Lund, Physics Department, Box 118, Lund (Sweden); CERN, PH Department, Geneva 23 (Switzerland); Hjorth-Jensen, M.; Engeland, T. [University of Oslo, Physics Department and Center of Mathematics for Applications, Oslo (Norway); Blazhev, A.; Eberth, J.; Finke, F.; Reiter, P.; Warr, N.; Weisshaar, D. [University of Cologne, Institute of Nuclear Physics, Cologne (Germany); Butler, P.A.; Hurst, A.M. [University of Liverpool, Oliver Lodge Laboratory, Liverpool (United Kingdom); Davinson, T. [University of Edinburgh, Department of Physics and Astronomy, Edinburgh (United Kingdom); Goergen, A. [Service de Physique Nucleaire, CEA Saclay, Gif-sur-Yvette (France); Gorska, M. [Gesellschaft fuer Schwerionenforschung, Darmstadt (Germany); Ivanov, O.; Stefanescu, I. [Instituut voor Kern- en Stralingsfysica, K.U. Leuven (Belgium); Iwanicki, J. [University of Warsaw, Heavy Ion Laboratory, Warsaw (Poland); Koester, U. [CERN, PH Department, Geneva 23 (Switzerland); Institut Laue Langevin, Grenoble (France); Marsh, B.A. [University of Manchester, Department of Physics, Manchester (United Kingdom); CERN, AB Department, Geneva 23 (Switzerland); Mierzejewski, J. [University of Warsaw, Heavy Ion Laboratory, Warsaw (Poland); University of Warsaw, Institute of Experimental Physics, Warsaw (Poland); Siem, S. [University of Oslo, Department of Physics, Oslo (Norway); Sletten, G. [University of Copenhagen, Physics Department, Copenhagen (Denmark); Tveten, G.M. [CERN, PH Department, Geneva 23 (Switzerland); University of Oslo, Department of Physics, Oslo (Norway); Van de Walle, J. [CERN, PH Department, Geneva 23 (Switzerland); Instituut voor Kern- en Stralingsfysica, K.U. Leuven (Belgium); Voulot, D.; Wenander, F. [CERN, AB Department, Geneva 23 (Switzerland)

    2010-06-15

    The low-lying states in the odd-odd and unstable isotopes {sup 106,108}In have been Coulomb excited from the ground state and the first excited isomeric state at the REX-ISOLDE facility at CERN. With the additional data provided here the {pi}g{sub 9/2}{sup -1} x {nu}d{sub 5/2} and {pi}g{sub 9/2}{sup -1} x {nu} g{sub 7/2} multiplets have been re-analyzed and are modified compared to previous results. The observed {gamma} -ray de-excitation patterns were interpreted within a shell model calculation based on a realistic effective interaction. The agreement between theory and experiment is satisfactory and the calculations reproduce the observed differences in the excitation pattern of the two isotopes. The calculations exclude a 6{sup +} ground state in {sup 106}In. This is in agreement with the conclusions drawn using other techniques. Furthermore, based on the experimental results, it is also concluded that the ordering of the isomeric and ground state in {sup 108}In is inverted compared to the shell model prediction. Limits on B(E2) values have been extracted where possible. A previously unknown low-lying state at 367keV in {sup 106}In is also reported. (orig.)

  3. Search for first 0 excited states in /sup 108/Cd and /sup 106/Cd

    CERN Document Server

    Roussière, B; Duffait, R; Genevey-Rivier, J; Kilcher, P; Meyer, M; Sauvage-Letessier, J; Tréherne, J

    1981-01-01

    The /sup 108/Cd and /sup 106/Cd isotopes have been studied from the beta /sup +//EC decay of /sup 108/In and /sup 106/In. gamma -rays, conversion electrons, gamma - gamma -t and e/sup -/- gamma -t coincidence measurements have been performed. Level schemes of /sup 108/Cd and /sup 106/Cd have been deduced from these results. A 0/sup + / level has been unambiguously established at 1.913 MeV in /sup 108/Cd and a new 0/sup +/ level proposed at 2.035 MeV in /sup 106/Cd. The energies and branching ratios are discussed in terms of vibrator +particles approach, interacting boson approximation and rotor +quasiparticles model. (15 refs).

  4. 0(gs)+ -->2(1)+ transition strengths in 106Sn and 108Sn.

    Science.gov (United States)

    Ekström, A; Cederkäll, J; Fahlander, C; Hjorth-Jensen, M; Ames, F; Butler, P A; Davinson, T; Eberth, J; Fincke, F; Görgen, A; Górska, M; Habs, D; Hurst, A M; Huyse, M; Ivanov, O; Iwanicki, J; Kester, O; Köster, U; Marsh, B A; Mierzejewski, J; Reiter, P; Scheit, H; Schwalm, D; Siem, S; Sletten, G; Stefanescu, I; Tveten, G M; Van de Walle, J; Van Duppen, P; Voulot, D; Warr, N; Weisshaar, D; Wenander, F; Zielińska, M

    2008-07-04

    The reduced transition probabilities, B(E2; 0(gs)+ -->2(1)+), have been measured in the radioactive isotopes (108,106)Sn using subbarrier Coulomb excitation at the REX-ISOLDE facility at CERN. Deexcitation gamma rays were detected by the highly segmented MINIBALL Ge-detector array. The results, B(E2;0(gs)+ -->2(1)+)=0.222(19)e2b2 for 108Sn and B(E2; 0(gs)+-->2(1)+)=0.195(39)e2b2 for 106Sn were determined relative to a stable 58Ni target. The resulting B(E2) values are approximately 30% larger than shell-model predictions and deviate from the generalized seniority model. This experimental result may point towards a weakening of the N=Z=50 shell closure.

  5. New isotopes of elements 104, 106 and 108 - highly stable superheavy nuclei

    International Nuclear Information System (INIS)

    Oganessian, Yuri

    1994-01-01

    In April 1993, as part of a joint Dubna-Livermore experiment at the Flerov Laboratory of Nuclear Reactions, new heavy isotopes of elements 104 and 106 were synthesized - 262 104, 265 106 and 266 106. Compared with the known even-even isotopes of elements 104 and 106, the new nuclei are characterized by their extraordinary high resistance to spontaneous fission. This is a direct proof of the macro-microscopic theory predictions in its version calculated by A.Sobiczewski et al. regarding a substantial increase in the half-lives of heavy nuclei near deformed shells with atomic number (Z) 108 and neutron number (N) 162.

  6. Coulomb excitation of the odd-odd isotopes $^{106, 108}$In

    CERN Document Server

    Ekstrom, A; Blazhev, A; Van de Walle, J; Weisshaar, D; Zielinska, M; Tveten, G M; Marsh, B A; Siem, S; Gorska, M; Engeland, T; Hurst, A M; Cederkall, J; Finke, F; Iwanicki, J; Hjorth-Jensen, M; Davinson, T; Eberth, J; Sletten, G; Mierzejewski, J; Reiter, P; Warr, N; Butler, P A; Fahlander, C; Stefanescu, I; Koester, U; Ivanov, O; Wenander, F; Voulot, D

    2010-01-01

    The low-lying states in the odd-odd and unstable isotopes In-106,In-108 have been Coulomb excited from the ground state and the first excited isomeric state at the REX-ISOLDE facility at CERN. With the additional data provided here the pi g(9/2)(-1) circle times nu d(5/2) and pi g(9/2)(-1) circle times nu g7/2 multiplets have been re-analyzed and are modified compared to previous results. The observed gamma-ray de-excitation patterns were interpreted within a shell model calculation based on a realistic effective interaction. The agreement between theory and experiment is satisfactory and the calculations reproduce the observed differences in the excitation pattern of the two isotopes. The calculations exclude a 6(+) ground state in In-106. This is in agreement with the conclusions drawn using other techniques. Furthermore, based on the experimental results, it is also concluded that the ordering of the isomeric and ground state in In-108 is inverted compared to the shell model prediction. Limits on B(E2) val...

  7. High-spin states in odd-odd 106,108,110,112Rh

    International Nuclear Information System (INIS)

    Fotiades, N.; Cizewski, J.A.; Kruecken, R.; McNabb, D.P.; Becker, J.A.; Bernstein, L.A.; Younes, W.; Clark, R.M.; Fallon, P.; Lee, I.Y.; Macchiavelli, A.O.

    2003-01-01

    The level structures of 106,108,110,112 Rh have been studied in the fission of the compound system formed in three different heavy-ion induced reactions. Sequences of five transitions, together with weak crossover transitions, have been assigned to each isotope based on coincidences with known transitions in the complementary fragments. Comparison with the lighter odd-odd Rh isotopes supports assignment of these sequences as the yrast bands built on the πg 9/2 xνh 11/2 configuration

  8. 29 CFR 1603.108 - Settlement and alternative dispute resolution.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Settlement and alternative dispute resolution. 1603.108... Settlement and alternative dispute resolution. (a) The parties are at all times free to settle all or part of... a neutral mediator or to any other alternative dispute resolution process authorized by the...

  9. Cu induced reactions on 110Cd-108Cd-106Cd, 109Ag-107Ag and 110Pd. New rhenium, osmium and iridium isotopes

    International Nuclear Information System (INIS)

    Cabot, C.; Della Negra, S.; Deprun, C.; Gauvin, H.; Le Beyec, Y.

    1978-01-01

    By 63 Cu induced reactions on 110 Cd, 108 Cd, 106 Cd, 109 Ag, 107 Ag and 110 Pd targets, new isotopes were searched in the Ir, Os, Re region. Cross bombardments and excitation function measurements were used to identify new α emitting isotopes. The α-decay measurements are compared to the Qα values obtained from different mass predictions

  10. The reorientation precession technique, REPREC, and the quadrupole moments of /sup 108/ /sup 110/Pd. [Sum rules

    Energy Technology Data Exchange (ETDEWEB)

    Hasselgren, L; Fahlander, C; Edvardson, L O; Thun, J E; Falk, F; Ghumman, B S

    1975-04-01

    The orientation precession technique, REPREC, for measurements of quadrupole moments is described. The application of REPREC to the measurement of the static electric quadrupole moments of the first excited 2/sup +/-states in /sup 108/ /sup 110/Pd is presented. The possibility to measure the matrix product P/sub 4/ = M/sub 02/M/sub 22/,M/sub 02/M/sub 22/ is also discussed. Such measurements are presented for /sup 108/ /sup 110/Pd. The results of these measurements are P/sub 4/O for both /sup 108/Pd and /sup 110/Pd. For /sup 108/Pd the quadrupole moment of the first excited 2/sup +/-state was found to be -.66 +- .18 eb and for /sup 110/Pd -.72 +- .14 eb. Intrinsic nuclear properties for /sup 106 -110/Pd are derived using the sum rules suggested by Kumar.

  11. Reorientation precession measurements on /sup 108/ /sup 110/Pd and the quadrupole moments of their first 2/sup +/ states

    Energy Technology Data Exchange (ETDEWEB)

    Hasselgren, L; Fahlander, C; Falk, F; Edvardson, L O; Thun, J E; Ghuman, B S [Uppsala Univ. (Sweden). Fysiska Institutionen; Skaali, B [Oslo Univ. (Norway). Fysisk Institutt

    1976-06-28

    The reorientation precession technique, REPREC, for measurements of quadrupole moments is described. The application of REPREC to the measurement of the static electric quadrupole moments of the first excited 2/sup +/ states in /sup 108/ /sup 110/Pd is presented. The possibility to measure the sign of the matrix product P/sub 4/ = M/sub 02/Msub(22')Msub(02')M/sub 22/ is also discussed. Such measurements are presented for /sup 108/ /sup 110/Pd. The results of these measurements are P/sub 4/ < 0 for both /sup 108/Pd and /sup 110/Pd. For /sup 108/Pd the quadrupole moment of the first excited 2/sup +/ state was found to be -0.66+-0.18e.b and for /sup 110/Pd, -0.72+-0.14e.b. Intrinsic nuclear properties for /sup 106 -110/Pd are derived using the sum rules suggested by Kumar.

  12. 24 CFR 1000.106 - What families receiving assistance under title II of NAHASDA require HUD approval?

    Science.gov (United States)

    2010-04-01

    ... under title II of NAHASDA require HUD approval? 1000.106 Section 1000.106 Housing and Urban Development... Housing Activities § 1000.106 What families receiving assistance under title II of NAHASDA require HUD... in §§ 1000.108 and 1000.110. (b) Assistance under section 201(b)(3) of NAHASDA for non-Indian...

  13. 29 CFR 1614.108 - Investigation of complaints.

    Science.gov (United States)

    2010-07-01

    ... Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION FEDERAL SECTOR EQUAL EMPLOYMENT OPPORTUNITY Agency Program To Promote Equal Employment Opportunity § 1614.108... encouraged to incorporate alternative dispute resolution techniques into their investigative efforts in order...

  14. About the value of Ruthenium 106 brachytherapy in the treatment of uveal melanomas

    International Nuclear Information System (INIS)

    Langmann, G.; Mosboeck, G.; Stuecklschwaiger, G.; Muellner, K.; Lechner, H.; Faulborn, J.

    2002-01-01

    Background: to investigate the clinical course, sequelae and visual function of uveal melanomas treated with Ruthenium 106 brachytherapy. Patients and method: 47 patients who underwent Ruthenium 106 brachytherapy between 1985 and 2000 were evaluated using Kaplan Meier statistical method. Mean follow up interval was 22 month (range 8 - 152 months). Results: Local tumor control rate was 85 %, 5 years possibility to avoid enucleation was 75 %. The most important sequelae were radiation optic neuropathy (29 %), maculopathy (37 %) and radiation retinopathy (32 %). After terminating the study the 34 % of the patients achieved a visual acuity of 20/40 and more, another 34 % had a visual function of 20/200 and lower. Conclusion: Ruthenium 106 brachytherapy is our method of choice in small medium sized uveal melanomas and a maximum tumor prominence of 6 mm. Tumors have to be located in the midperiphery and outer periphery of the fundus including the ciliary body. In addition to the indications introduced by Lommatzsch we treated ciliary body melanomas with a tumor base more than 3 clock hours (by shifting the plaque) as an alternative therapy to enucleation. (author)

  15. Constraints to the possible alternatives from Arizona agriculture

    Energy Technology Data Exchange (ETDEWEB)

    Foster, K.E.

    1979-01-01

    The problems plaguing Arizona agriculture are outlined including the primary factors of declining groundwater supplies and increasing costs of energy to pump irrigation water. Two alternatives are suggested. The first alternative is to reduce or stabilize energy costs, an event that the authors acknowledge as being rather unlikely. Pumping costs using various fuels during the period 1891 to 1978 are reviewed. The second alternative involves developing cultivation techniques for drought-resistant plants native to arid regions, plants which have economic potential. Most of these plants would require little irrigation under cultivation and could substitute for cash crops being cultivated under heavy irrigation in Arizona. Four of these plants native to arid regions in the United States are discussed in some detail. Guayule (Parthenium argentatum) is a known rubber producer. Jojoba (Simmondsia chinensis) produces a liquid wax similar to the oil of the sperm whale, an endangered species. The gopher plant (Euphorbia lathyrus) is a potential producer of petrochemical feedstock for use as an energy source. Finally the buffalo gourd (Cucurbita foetidissima) is a possible source of food for both humans and livestock.

  16. Project W-320 Tank 106-C waste retrieval study analysis session report

    International Nuclear Information System (INIS)

    Bailey, J.W.

    1998-01-01

    This supporting document has been prepared to make the Kaiser Engineers Hanford Company Project W-320 Tank 106-C Waste Retrieval Study Analysis Session Report readily retrievable. This facilitated session was requested by Westinghouse Hanford Company (WHC) to review the characterization data and select the best alternatives for a double-shell receiver tank and for a sluicing medium for Tank 106-C waste retrieval. The team was composed of WHC and Kaiser Engineers Hanford Company (KEH) personnel knowledgeable about tank farm operations, tank 106-C requirements, tank waste characterization and analysis, and chemical processing. This team was assembled to perform a structured decision analysis evaluation and recommend the best alternative-destination double-shell tank between tanks 101-AY and 102-AY, and the best alternative sluicing medium among dilute complexant (DC), dilute noncomplexant (DNC), and water. The session was facilitated by Richard Harrington and Steve Bork of KEH and was conducted at the Bookwalter Winery in Richland from 7:30 a.m. to 4:00 p.m. from July 27 through July 29, 1993. Attachment 1 (Scope Statement Sheet) identifies the team members, scope, objectives, and deliverables for the session

  17. 14 CFR 1275.106 - Administrative actions.

    Science.gov (United States)

    2010-01-01

    ... 1275.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275... correct the research record. The administrative actions range from minimal restrictions (Group I Actions) to severe restrictions (Group III Actions), and do not include possible criminal sanctions. (1) Group...

  18. Chemistry gains a new element: Z=106

    International Nuclear Information System (INIS)

    Gaeggeler, H.W.; Eichler, B.; Tuerler, A.

    1997-01-01

    Even though 112 chemical elements are presently known, for elements with atomic numbers above 105 only nuclear decay properties have been investigated so far. Such data allow to proof the existence of a given nuclide, but they do not yield any information with respect to the position of a chemical element in the Periodic Table. We have performed ever first chemical investigations of element 106. According to the Periodic Table element 106 should be a member of group 6, having similar chemical properties as W, Mo and Cr. Two different techniques were applied to separate and identify element 106: a liquid chromatography system (ARCA = Automated Rapid Chemistry Apparatus) and a continuous isothermal chromatography device (OLGA = On-Line Gaschemistry Apparatus). With ARCA about 5'000 separations on small cation exchange columns (Aminex A6) with a 0.1 M HNO 3 /5.10 -4 M Hf solution were performed and with OLGA the gas adsorption behaviour of oxychlorides on quartz columns using Cl 2 /SOCl 2 /O 2 as reactive gas were studied. On the basis of only ten detected atoms, it was possible to proof that element 106 forms complexes which are eluted at positions similar to those of Mo and W. In addition, in the gas phase element 106 forms oxychlorides of lower volatility compared to those of Mo and W. (author) 1 ref

  19. Crystal structures of human 108V and 108M catechol O-methyltransferase

    Energy Technology Data Exchange (ETDEWEB)

    Rutherford, K.; Le Trong, I.; Stenkamp, R.E.; Parson, W.W. (UWASH)

    2008-08-01

    Catechol O-methyltransferase (COMT) plays important roles in the metabolism of catecholamine neurotransmitters and catechol estrogens. The development of COMT inhibitors for use in the treatment of Parkinson's disease has been aided by crystallographic structures of the rat enzyme. However, the human and rat proteins have significantly different substrate specificities. Additionally, human COMT contains a common valine-methionine polymorphism at position 108. The methionine protein is less stable than the valine polymorph, resulting in decreased enzyme activity and protein levels in vivo. Here we describe the crystal structures of the 108V and 108M variants of the soluble form of human COMT bound with S-adenosylmethionine (SAM) and a substrate analog, 3,5-dinitrocatechol. The polymorphic residue 108 is located in the {alpha}5-{beta}3 loop, buried in a hydrophobic pocket {approx}16 {angstrom} from the SAM-binding site. The 108V and 108M structures are very similar overall [RMSD of C{sup {alpha}} atoms between two structures (C{sup {alpha}} RMSD) = 0.2 {angstrom}], and the active-site residues are superposable, in accord with the observation that SAM stabilizes 108M COMT. However, the methionine side chain is packed more tightly within the polymorphic site and, consequently, interacts more closely with residues A22 ({alpha}2) and R78 ({alpha}4) than does valine. These interactions of the larger methionine result in a 0.7-{angstrom} displacement in the backbone structure near residue 108, which propagates along {alpha}1 and {alpha}5 toward the SAM-binding site. Although the overall secondary structures of the human and rat proteins are very similar (C{sup {alpha}} RMSD = 0.4 {angstrom}), several nonconserved residues are present in the SAM-(I89M, I91M, C95Y) and catechol- (C173V, R201M, E202K) binding sites. The human protein also contains three additional solvent-exposed cysteine residues (C95, C173, C188) that may contribute to intermolecular disulfide bond

  20. 40 CFR 280.108 - Substitution of financial assurance mechanisms by owner or operator.

    Science.gov (United States)

    2010-07-01

    ... alternate financial assurance mechanisms as specified in this subpart, provided that at all times he... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Substitution of financial assurance... OWNERS AND OPERATORS OF UNDERGROUND STORAGE TANKS (UST) Financial Responsibility § 280.108 Substitution...

  1. 49 CFR 24.108 - Donations.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Donations. 24.108 Section 24.108 Transportation Office of the Secretary of Transportation UNIFORM RELOCATION ASSISTANCE AND REAL PROPERTY ACQUISITION FOR FEDERAL AND FEDERALLY-ASSISTED PROGRAMS Real Property Acquisition § 24.108 Donations. An owner whose real...

  2. 46 CFR 108.235 - Construction.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Construction. 108.235 Section 108.235 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Construction and Arrangement Helicopter Facilities § 108.235 Construction. (a) Each helicopter deck must be...

  3. 34 CFR 106.71 - Procedures.

    Science.gov (United States)

    2010-07-01

    ...) Public institutions of undergraduate higher education, 106.15(e) Recruitment, [34, 35]; 106.23 Specific...(d) Pre-Employment Inquiry Recruitment, [83, 90, 91, 95] Sex as a BFOQ, [96]; 106.61 Student... organizations”, 106.31(c) Fraternities/Sororities Social, [53, 27, 28]; 106.14(a) Business/professional, [40, 53...

  4. 18 CFR 286.108 - Determination.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Determination. 286.108 Section 286.108 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT... Contested Audit Findings and Proposed Remedies § 286.108 Determination. If no formal hearing is had the...

  5. 46 CFR 108.493 - Location.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Location. 108.493 Section 108.493 Shipping COAST GUARD... Extinguishing Systems Hand Portable and Semiportable Fire Extinguishing Systems § 108.493 Location. (a) Each... this subpart and installed in the locations prescribed in the table. (b) Each portable and semi...

  6. 24 CFR 908.108 - Cost.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Cost. 908.108 Section 908.108..., RENTAL VOUCHER, AND MODERATE REHABILITATION PROGRAMS § 908.108 Cost. (a) General. The costs of the... computer hardware or software, or both, the cost of contracting for those services, or the cost of...

  7. 24 CFR 108.25 - Compliance meeting.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Compliance meeting. 108.25 Section... COMPLIANCE PROCEDURES FOR AFFIRMATIVE FAIR HOUSING MARKETING § 108.25 Compliance meeting. (a) Scheduling meeting. If an applicant fails to comply with requirements under § 108.15 or § 108.20 or it appears that...

  8. 7 CFR 1150.108 - Eligible organization.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Eligible organization. 1150.108 Section 1150.108 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Order Definitions § 1150.108 Eligible organization. Eligible organization means any organization which...

  9. 28 CFR 551.108 - Performance pay.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Performance pay. 551.108 Section 551.108 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT MISCELLANEOUS Pretrial Inmates § 551.108 Performance pay. The Warden may approve a pretrial inmate for performance pay...

  10. 40 CFR 211.108 - Sample label.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Sample label. 211.108 Section 211.108 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS PRODUCT NOISE LABELING General Provisions § 211.108 Sample label. Examples of labels conforming to the requirements of...

  11. 48 CFR 3028.106 - Administration.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Administration. 3028.106 Section 3028.106 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND SECURITY... 3028.106 Administration. ...

  12. 46 CFR 108.653 - Helicopter facilities.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Helicopter facilities. 108.653 Section 108.653 Shipping... EQUIPMENT Equipment Markings and Instructions § 108.653 Helicopter facilities. (a) Each helicopter fueling facility must be marked adjacent to the fueling hose storage: “WARNING—HELICOPTER FUELING STATION—KEEP...

  13. 46 CFR 108.241 - Visual aids.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Visual aids. 108.241 Section 108.241 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Construction and Arrangement Helicopter Facilities § 108.241 Visual aids. (a) Each helicopter deck must— (1...

  14. 7 CFR 1260.108 - United States.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false United States. 1260.108 Section 1260.108 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Promotion and Research Order Definitions § 1260.108 United States. United States means the 50 States and the...

  15. 42 CFR 401.108 - CMS rulings.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false CMS rulings. 401.108 Section 401.108 Public Health... GENERAL ADMINISTRATIVE REQUIREMENTS Confidentiality and Disclosure § 401.108 CMS rulings. (a) After... regulations, but which has been adopted by CMS as having precedent, may be published in the Federal Register...

  16. 46 CFR 108.499 - Fire axes.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Fire axes. 108.499 Section 108.499 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems Miscellaneous Firefighting Equipment § 108.499 Fire axes. Each unit must have at least two...

  17. 13 CFR 108.100 - Business form.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Business form. 108.100 Section 108.100 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL (âNMVCâ) PROGRAM Qualifications for the NMVC Program Organizing A Nmvc Company § 108.100 Business form. A NMVC...

  18. 22 CFR 41.108 - Medical examination.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Medical examination. 41.108 Section 41.108... AND NATIONALITY ACT, AS AMENDED Application for Nonimmigrant Visa § 41.108 Medical examination. (a) Requirements for medical examination. An applicant for a nonimmigrant visa shall be required to take a medical...

  19. 46 CFR 108.471 - Water pump.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Water pump. 108.471 Section 108.471 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems Foam Extinguishing Systems § 108.471 Water pump. Each water pump in a foam extinguishing...

  20. 12 CFR 347.108 - Portfolio investments.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Portfolio investments. 347.108 Section 347.108... INTERNATIONAL BANKING § 347.108 Portfolio investments. (a) Portfolio investments. If a bank, directly or indirectly, acquires or holds an equity interest in a foreign organization as a portfolio investment and the...

  1. 48 CFR 2828.106 - Administration.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Administration. 2828.106 Section 2828.106 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE General Contracting Requirements BONDS AND INSURANCE Bonds 2828.106 Administration. ...

  2. 48 CFR 1028.106 - Administration.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Administration. 1028.106 Section 1028.106 Federal Acquisition Regulations System DEPARTMENT OF THE TREASURY GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Bonds 1028.106 Administration. ...

  3. 46 CFR 108.486 - Helicopter decks.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Helicopter decks. 108.486 Section 108.486 Shipping COAST... Fire Extinguishing Systems Fire Protection for Helicopter Facilities § 108.486 Helicopter decks. At least two of the accesses to the helicopter landing deck must each have a fire hydrant on the unit's...

  4. 46 CFR 108.143 - Accommodation space.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Accommodation space. 108.143 Section 108.143 Shipping... EQUIPMENT Construction and Arrangement Structural Fire Protection § 108.143 Accommodation space. (a) Each corridor bulkhead in an accommodation space must be an A class or B class bulkhead except if an A class...

  5. 46 CFR 108.601 - Crane design.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Crane design. 108.601 Section 108.601 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Cranes Cranes § 108.601 Crane design. (a) Each crane and crane foundation on a unit must be designed in...

  6. 46 CFR 108.213 - Heating requirements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Heating requirements. 108.213 Section 108.213 Shipping... EQUIPMENT Construction and Arrangement Accommodation Spaces § 108.213 Heating requirements. (a) Each accommodation space must be heated by a heating system that can maintain at least 20°C. (68°F.). (b) Radiators...

  7. 46 CFR 108.221 - Storm rails.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Storm rails. 108.221 Section 108.221 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Construction and Arrangement Rails § 108.221 Storm rails. Each unit must have a storm rail in the following...

  8. 40 CFR 94.108 - Test fuels.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Test fuels. 94.108 Section 94.108... EMISSIONS FROM MARINE COMPRESSION-IGNITION ENGINES Test Procedures § 94.108 Test fuels. (a) Distillate diesel test fuel. (1) The diesel fuels for testing Category 1 and Category 2 marine engines designed to...

  9. 46 CFR 108.467 - Water supply.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Water supply. 108.467 Section 108.467 Shipping COAST... Fire Extinguishing Systems Foam Extinguishing Systems § 108.467 Water supply. The water supply of a foam extinguishing system must not be the water supply of the fire main system on the unit unless when...

  10. 48 CFR 228.106 - Administration.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Administration. 228.106 Section 228.106 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Bonds 228.106 Administration. ...

  11. 48 CFR 1228.106 - Administration.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Administration. 1228.106 Section 1228.106 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Bonds and Other Financial Protections 1228.106 Administration. ...

  12. 48 CFR 828.106 - Administration.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Administration. 828.106 Section 828.106 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Bonds and Other Financial Protections 828.106 Administration. ...

  13. 48 CFR 428.106 - Administration.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Administration. 428.106 Section 428.106 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Bonds and Other Financial Protections 428.106 Administration. ...

  14. 48 CFR 1328.106 - Administration.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Administration. 1328.106 Section 1328.106 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Bonds and Other Financial Protections 1328.106 Administration. ...

  15. Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency.

    Science.gov (United States)

    Arrant, Andrew E; Nicholson, Alexandra M; Zhou, Xiaolai; Rademakers, Rosa; Roberson, Erik D

    2018-06-22

    Loss of function mutations in progranulin (GRN) are a major cause of frontotemporal dementia (FTD). Progranulin is a secreted glycoprotein that localizes to lysosomes and is critical for proper lysosomal function. Heterozygous GRN mutation carriers develop FTD with TDP-43 pathology and exhibit signs of lysosomal dysfunction in the brain, with increased levels of lysosomal proteins and lipofuscin accumulation. Homozygous GRN mutation carriers develop neuronal ceroid lipofuscinosis (NCL), an earlier-onset lysosomal storage disorder caused by severe lysosomal dysfunction. Multiple genome-wide association studies have shown that risk of FTD in GRN mutation carriers is modified by polymorphisms in TMEM106B, which encodes a lysosomal membrane protein. Risk alleles of TMEM106B may increase TMEM106B levels through a variety of mechanisms. Brains from FTD patients with GRN mutations exhibit increased TMEM106B expression, and protective TMEM106B polymorphisms are associated with decreased TMEM106B expression. Together, these data raise the possibility that reduction of TMEM106B levels may protect against the pathogenic effects of progranulin haploinsufficiency. We crossed Tmem106b +/- mice with Grn +/- mice, which model the progranulin haploinsufficiency of GRN mutation carriers and develop age-dependent social deficits and lysosomal abnormalities in the brain. We tested whether partial Tmem106b reduction could normalize the social deficits and lysosomal abnormalities of Grn +/- mice. Partial reduction of Tmem106b levels did not correct the social deficits of Grn +/- mice. Tmem106b reduction also failed to normalize most lysosomal abnormalities of Grn +/- mice, except for β-glucuronidase activity, which was suppressed by Tmem106b reduction and increased by progranulin insufficiency. These data do not support the hypothesis that Tmem106b reduction protects against the pathogenic effects of progranulin haploinsufficiency, but do show that Tmem106b reduction normalizes some

  16. NP108, an Antimicrobial Polymer with Activity against Methicillin- and Mupirocin-Resistant Staphylococcus aureus

    Science.gov (United States)

    Katvars, Laura K.; Hewitt, Fiona; Smith, Daniel W.; Robertson, Jennifer; O'Neil, Deborah A.

    2017-01-01

    ABSTRACT Staphylococcus aureus is a clinically significant human pathogen that causes infectious diseases ranging from skin and soft tissue infections (SSTI) and health care-associated infections (HAI) to potentially fatal bacteremia and endocarditis. Nasal carriage of S. aureus, especially for persistent carriage, is associated with an increased risk of subsequent infection, particularly nosocomial and surgical site infections (SSI), usually via autoinfection. NP108 is a cationic antimicrobial polymer composed of generally recognized as safe (GRAS) amino acid building blocks. NP108 is broad spectrum and rapidly bactericidal (3-log kill in ≤3 h), killing bacteria by membrane disruption and cell lysis. NP108, contrary to many antibiotics, shows equally effective antimicrobial activity against a variety of S. aureus (MIC100 = 8 to 500 mg/liter) and S. epidermidis (MIC100 = 4 to 8 mg/liter) isolates, whether exponentially growing or in stationary phase. NP108 is antimicrobially active under nutrient-limiting conditions similar to those found in the anterior nares (MIC100 = 8 mg/liter) and kills antibiotic-resilient small colony variants (MIC100 = 32 mg/liter) and S. aureus biofilms (prevention, MIC100 = 1 to 4 mg/liter; eradication, MIC100 ≥ 31.25 mg/liter). NP108 is active against isolates of S. aureus resistant to the current standard-of-care decolonization agent, mupirocin, with no significant increase in the MIC100. NP108 is water soluble and has been formulated into compatible aqueous gel vehicles for human use in which antimicrobial efficacy is retained (2.0% [wt/vol]). NP108 is a potential nonantibiotic antimicrobial alternative to antibiotics for the nasal decolonization of S. aureus, with clear advantages in its mechanism of action over the existing gold standard, mupirocin. PMID:28607014

  17. 15 CFR 200.106 - Publications.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Publications. 200.106 Section 200.106... FEES § 200.106 Publications. Publications provide the primary means of communicating the results of the... issues some fifteen categories of publications including three periodicals, ten non-periodicals series...

  18. 7 CFR 1924.106 - Location.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Location. 1924.106 Section 1924.106 Agriculture... CONSTRUCTION AND REPAIR Planning and Performing Site Development Work § 1924.106 Location. (a) General. It is... will not finance development on locations that adversely affect properties which are listed or are...

  19. 34 CFR 106.23 - Recruitment.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Recruitment. 106.23 Section 106.23 Education... Discrimination on the Basis of Sex in Admission and Recruitment Prohibited § 106.23 Recruitment. (a) Nondiscriminatory recruitment. A recipient to which this subpart applies shall not discriminate on the basis of sex...

  20. 42 CFR 401.106 - Publication.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Publication. 401.106 Section 401.106 Public Health... GENERAL ADMINISTRATIVE REQUIREMENTS Confidentiality and Disclosure § 401.106 Publication. (a) Methods of publication. Materials required to be published under the provisions of The Freedom of Information Act, 5 U.S...

  1. 29 CFR 4.106 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true [Reserved] 4.106 Section 4.106 Labor Office of the Secretary of Labor LABOR STANDARDS FOR FEDERAL SERVICE CONTRACTS Application of the McNamara-O'Hara Service Contract Act Introductory § 4.106 [Reserved] Agencies Whose Contracts May Be Covered ...

  2. 47 CFR 25.105-25.108 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false [Reserved] 25.105-25.108 Section 25.105-25.108 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES SATELLITE COMMUNICATIONS General §§ 25.105-25.108 [Reserved] ...

  3. 42 CFR 93.108 - Confidentiality.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Confidentiality. 93.108 Section 93.108 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH...

  4. Safety equipment list for 241-C-106 waste retrieval, Project W-320: Revision 1

    International Nuclear Information System (INIS)

    Conner, J.C.

    1994-01-01

    The goals of the C-106 sluicing operation are: (1) to stabilize the tank by reducing the heat load in the tank to less than 42 MJ/hr (40,000 Btu/hour), and (2) to initiate demonstration of single-shell tank (SST) retrieval technology. The purpose of this supporting document (SD) is as follows: (1) to provide safety classifications for items (systems, structures, equipment, components, or parts) for the waste retrieval sluicing system (WRSS), and (2) to document and methodology used to develop safety classifications. Appropriate references are made with regard to use of existing systems, structures, equipments, components, and parts for C-106 single-shell transfer tank located in the C Tank Farm, and 241-AY-102 (AY-102) double shell receiver tanks (DST) located in the Aging Waste Facility (AWF). The Waste Retrieval Sluicing System consists of two transfer lines that would connect the two tanks, one to carry the sluiced waste slurry to AY-102, and the other to return the supernatant liquid to C-106. The supernatant, or alternate fluid, will be used to mobilize waste in C-106 for the sluicing process. The equipment necessary for the WRSS include pumps in each tank, sluicers to direct the supernatant stream in C-106, a slurry distributor in AY-102, HVAC for C-106, instrumentation and control devices, and other existing components as required

  5. 21 CFR 106.90 - Coding.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Coding. 106.90 Section 106.90 Food and Drugs FOOD... of Infant Formulas § 106.90 Coding. The manufacturer shall code all infant formulas in conformity with the coding requirements that are applicable to thermally processed low-acid foods packaged in...

  6. 34 CFR 106.32 - Housing.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Housing. 106.32 Section 106.32 Education Regulations of... Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 106.32 Housing. (a) Generally... fees or requirements, or offer different services or benefits related to housing, except as provided in...

  7. 34 CFR 106.51 - Employment.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Employment. 106.51 Section 106.51 Education Regulations... Discrimination on the Basis of Sex in Employment in Education Programs or Activities Prohibited § 106.51 Employment. (a) General. (1) No person shall, on the basis of sex, be excluded from participation in, be...

  8. Site investigation SFR. Boremap mapping of percussion drilled borehole HFR106

    Energy Technology Data Exchange (ETDEWEB)

    Winell, Sofia (Geosigma AB (Sweden))

    2010-06-15

    This report presents the result from the Boremap mapping of the percussion drilled borehole HFR106, which is drilled from an islet located ca 220 m southeast of the pier above SFR. The purpose of the location and orientation of the borehole is to investigate the possible occurrence of gently dipping, water-bearing structures in the area. HFR106 has a length of 190.4 m and oriented 269.4 deg/-60.9 deg. The mapping is based on the borehole image (BIPS), investigation of drill cuttings and generalized, as well as more detailed geophysical logs. The dominating rock type, which occupies 68% of HFR106, is fine- to medium-grained, pinkish grey metagranite-granodiorite (rock code 101057) mapped as foliated with a medium to strong intensity. Pegmatite to pegmatitic granite (rock code 101061) occupies 29% of the borehole. Subordinate rock types are felsic to intermediate meta volcanic rock (rock code 103076) and fine- to medium-grained granite (rock code 111058). Rock occurrences (rock types < 1 m in length) occupy about 16% of the mapped interval, of which half is veins, dykes and unspecified occurrences of pegmatite and pegmatitic granite. Only 5.5% of HFR106 is inferred to be altered, mainly oxidation in two intervals with an increased fracture frequency. A total number of 845 fractures are registered in HFR106. Of these are 64 interpreted as open with a certain aperture, 230 open with a possible aperture, and 551 sealed. This result in the following fracture frequencies: 1.6 open fractures/m and 3.0 sealed fractures/m. Three fracture sets of open and sealed fractures with the orientations 290 deg/70 deg, 150 deg/85 deg and 200 deg/85 deg can be distinguished in HFR106. The fracture frequency is generally higher in the second half of the borehole, and particularly in the interval 176-187.4 m.

  9. Site investigation SFR. Boremap mapping of percussion drilled borehole HFR106

    International Nuclear Information System (INIS)

    Winell, Sofia

    2010-06-01

    This report presents the result from the Boremap mapping of the percussion drilled borehole HFR106, which is drilled from an islet located ca 220 m southeast of the pier above SFR. The purpose of the location and orientation of the borehole is to investigate the possible occurrence of gently dipping, water-bearing structures in the area. HFR106 has a length of 190.4 m and oriented 269.4 deg/-60.9 deg. The mapping is based on the borehole image (BIPS), investigation of drill cuttings and generalized, as well as more detailed geophysical logs. The dominating rock type, which occupies 68% of HFR106, is fine- to medium-grained, pinkish grey metagranite-granodiorite (rock code 101057) mapped as foliated with a medium to strong intensity. Pegmatite to pegmatitic granite (rock code 101061) occupies 29% of the borehole. Subordinate rock types are felsic to intermediate meta volcanic rock (rock code 103076) and fine- to medium-grained granite (rock code 111058). Rock occurrences (rock types < 1 m in length) occupy about 16% of the mapped interval, of which half is veins, dykes and unspecified occurrences of pegmatite and pegmatitic granite. Only 5.5% of HFR106 is inferred to be altered, mainly oxidation in two intervals with an increased fracture frequency. A total number of 845 fractures are registered in HFR106. Of these are 64 interpreted as open with a certain aperture, 230 open with a possible aperture, and 551 sealed. This result in the following fracture frequencies: 1.6 open fractures/m and 3.0 sealed fractures/m. Three fracture sets of open and sealed fractures with the orientations 290 deg/70 deg, 150 deg/85 deg and 200 deg/85 deg can be distinguished in HFR106. The fracture frequency is generally higher in the second half of the borehole, and particularly in the interval 176-187.4 m

  10. Metabolism and dosimetry of 106Ru inhaled as 106RuO4 by beagle dogs

    International Nuclear Information System (INIS)

    Snipes, M.B.

    1981-01-01

    This report provides metabolism and dosimetry data for inhaled ruthenium developed from studies in Beagle dogs that were exposed by inhalation to 106 RuO 4 . Twenty-six dogs were exposed nose-only to 106 RuO 4 and sacrificed at times from 2 hr to 512 days after inhalation exposure. Ninety-nine percent of the initial body burden was retained with an effective half-time of 1.2 days, 0.7% with a half-time of 14 days and 0.3% with a half-time of 170 days. Initial deposition was primarily in the nasopharyngeal and tracheobronchial regions. Results for deposition and retention of 106 Ru inhaled as 106 RuO 4 in dogs were similar to what has been observed for humans. The data for dogs were used to develop a model to predict potential radiation exposure patterns for humans after inhalation exposure to 106 RuO 4 . The model indicates that for humans the nasopharyngeal region, lower large intestine, and tracheobronchial epithelium would receive approx. 36, 13 and 10 times, respectively, the dose to 500 days after inhalation exposure to 106 RuO 4 that the lung would receive. The nasopharyngeal region should be considered the critical region for inhalation exposures to 106 RuO 4 . (author)

  11. 46 CFR 108.489 - Helicopter fueling facilities.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Helicopter fueling facilities. 108.489 Section 108.489... AND EQUIPMENT Fire Extinguishing Systems Fire Protection for Helicopter Facilities § 108.489 Helicopter fueling facilities. (a) Each helicopter fueling facility must have a fire protection system that...

  12. 9 CFR 108.8 - Construction of buildings.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Construction of buildings. 108.8 Section 108.8 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF... LICENSED ESTABLISHMENTS § 108.8 Construction of buildings. (a) The floors, walls, ceilings, partitions...

  13. 47 CFR 68.108 - Incidence of harm.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Incidence of harm. 68.108 Section 68.108 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) CONNECTION OF TERMINAL EQUIPMENT TO THE TELEPHONE NETWORK Conditions on Use of Terminal Equipment § 68.108 Incidence of...

  14. 46 CFR 108.580 - Personal lifesaving appliances.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Personal lifesaving appliances. 108.580 Section 108.580 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Lifesaving Equipment § 108.580 Personal lifesaving appliances. (a) Lifebuoys. Each unit...

  15. 17 CFR 10.108 - Settlements.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Settlements. 10.108 Section 10... to the Commission; Settlements § 10.108 Settlements. (a) When offers may be made. Parties may at any time during the course of the proceeding propose offers of settlement. All offers of settlement shall...

  16. 7 CFR 1710.108 - Mergers and consolidations.

    Science.gov (United States)

    2010-01-01

    ... operating efficiency and financial soundness. (b) After a merger or consolidation, RUS will give priority... 7 Agriculture 11 2010-01-01 2010-01-01 false Mergers and consolidations. 1710.108 Section 1710.108... and Basic Policies § 1710.108 Mergers and consolidations. (a) RUS encourages its borrowers to consider...

  17. 48 CFR 852.233-70 - Protest content/alternative dispute resolution.

    Science.gov (United States)

    2010-10-01

    .../alternative dispute resolution. 852.233-70 Section 852.233-70 Federal Acquisition Regulations System... Provisions and Clauses § 852.233-70 Protest content/alternative dispute resolution. As prescribed in 833.106, insert the following provision: Protest Content/Alternative Dispute Resolution (JAN 2008) (a) Any protest...

  18. Assessment of ocular beta radiation dose distribution due to 106Ru/106Rh brachytherapy applicators using MCNPX Monte Carlo code

    Directory of Open Access Journals (Sweden)

    Nilseia Aparecida Barbosa

    2014-08-01

    Full Text Available Purpose: Melanoma at the choroid region is the most common primary cancer that affects the eye in adult patients. Concave ophthalmic applicators with 106Ru/106Rh beta sources are the more used for treatment of these eye lesions, mainly lesions with small and medium dimensions. The available treatment planning system for 106Ru applicators is based on dose distributions on a homogeneous water sphere eye model, resulting in a lack of data in the literature of dose distributions in the eye radiosensitive structures, information that may be crucial to improve the treatment planning process, aiming the maintenance of visual acuity. Methods: The Monte Carlo code MCNPX was used to calculate the dose distribution in a complete mathematical model of the human eye containing a choroid melanoma; considering the eye actual dimensions and its various component structures, due to an ophthalmic brachytherapy treatment, using 106Ru/106Rh beta-ray sources. Two possibilities were analyzed; a simple water eye and a heterogeneous eye considering all its structures. Two concave applicators, CCA and CCB manufactured by BEBIG and a complete mathematical model of the human eye were modeled using the MCNPX code. Results and Conclusion: For both eye models, namely water model and heterogeneous model, mean dose values simulated for the same eye regions are, in general, very similar, excepting for regions very distant from the applicator, where mean dose values are very low, uncertainties are higher and relative differences may reach 20.4%. For the tumor base and the eye structures closest to the applicator, such as sclera, choroid and retina, the maximum difference observed was 4%, presenting the heterogeneous model higher mean dose values. For the other eye regions, the higher doses were obtained when the homogeneous water eye model is taken into consideration. Mean dose distributions determined for the homogeneous water eye model are similar to those obtained for the

  19. 46 CFR 108.651 - Portable magazine chests.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Portable magazine chests. 108.651 Section 108.651... AND EQUIPMENT Equipment Markings and Instructions § 108.651 Portable magazine chests. Each portable magazine chest must be marked: “PORTABLE MAGAZINE CHEST—FLAMMABLE—KEEP LIGHTS AND FIRE AWAY” in letters at...

  20. 46 CFR 108.719 - Pilot boarding equipment.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Pilot boarding equipment. 108.719 Section 108.719... AND EQUIPMENT Miscellaneous Equipment § 108.719 Pilot boarding equipment. (a) This section applies to... vessel must have suitable pilot boarding equipment available for use on each side of the vessel. If a...

  1. 29 CFR 552.108 - Child labor provisions.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Child labor provisions. 552.108 Section 552.108 Labor... OF THE FAIR LABOR STANDARDS ACT TO DOMESTIC SERVICE Interpretations § 552.108 Child labor provisions. Congress made no change in section 12 as regards domestic service employees. Accordingly, the child labor...

  2. 46 CFR 108.411 - Smoke detection system.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Smoke detection system. 108.411 Section 108.411 Shipping... EQUIPMENT Fire Extinguishing Systems § 108.411 Smoke detection system. Each smoke accumulator in a smoke detection system must be located on the overhead of the compartment protected by the system in a location...

  3. 46 CFR 108.627 - Carbon dioxide alarm.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Carbon dioxide alarm. 108.627 Section 108.627 Shipping... EQUIPMENT Equipment Markings and Instructions § 108.627 Carbon dioxide alarm. Each carbon dioxide alarm must be identified by marking: “WHEN ALARM SOUNDS VACATE AT ONCE. CARBON DIOXIDE BEING RELEASED” next to...

  4. 29 CFR 452.108 - Publication of results.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Publication of results. 452.108 Section 452.108 Labor... DISCLOSURE ACT OF 1959 Election Procedures; Rights of Members § 452.108 Publication of results. In any... one local, publication may be accomplished by posting on appropriate bulletin boards, or in a union...

  5. 7 CFR 1150.106 - United States.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true United States. 1150.106 Section 1150.106 Agriculture... Order Definitions § 1150.106 United States. United States means the 48 contiguous States in the continental United States. ...

  6. 46 CFR 108.463 - Foam rate: Protein.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Foam rate: Protein. 108.463 Section 108.463 Shipping... EQUIPMENT Fire Extinguishing Systems Foam Extinguishing Systems § 108.463 Foam rate: Protein. (a) If the outlets of a protein foam extinguishing system are in a space, the foam rate at each outlet must be at...

  7. 46 CFR 108.405 - Fire detection system.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Fire detection system. 108.405 Section 108.405 Shipping... EQUIPMENT Fire Extinguishing Systems § 108.405 Fire detection system. (a) Each fire detection system and each smoke detection system on a unit must— (1) Be approved by the Commandant; and (2) Have a visual...

  8. 46 CFR 108.707 - First aid kit.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false First aid kit. 108.707 Section 108.707 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Miscellaneous Equipment § 108.707 First aid kit. Each unit must have a first-aid kit approved by the Mine Safety...

  9. Experience in usage of T-108 titrimetric laboratory unit for precision analysis of uranium-containing materials

    International Nuclear Information System (INIS)

    Ryzhinskij, M.V.; Bronzov, P.A.

    1989-01-01

    Possibilities of the T-108 device of potentiometric titration for precise determination of uranium in various uranium-containing materials are studied, the results being presented. Principle flowsheet of the device and the sequence of analytic procedure of uranium potentiometric titration are considered. U 3 O 8 , UO 2 and UF 4 were used as materials to be analyzed, state standard samples of K 2 Cr 2 O 7 -SSS 2215-81 and U 3 O 8 SSS 2396-83P- as standard samples. It is shown that relative standard deviation during titration using the T-108 device is mainly determined by the error of determination of the final titration point potention and it must not exceed 0.002 for uranium titration considered. The conclusion is made that the variant of potentiometric titration of uranium with the use of the T-108 device is not inferior in its accuracy to gravimetry and surpasses it in productivity and possibility of automation. 4 refs.; 2 figs.; 2 tabs

  10. 48 CFR 45.106 - Transferring accountability.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Transferring accountability. 45.106 Section 45.106 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT GOVERNMENT PROPERTY General 45.106 Transferring accountability. Government property...

  11. 12 CFR 702.108 - Risk mitigation credit.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Risk mitigation credit. 702.108 Section 702.108... CORRECTIVE ACTION Net Worth Classification § 702.108 Risk mitigation credit. (a) Who may apply. A credit union may apply for a risk mitigation credit if on any of the current or three preceding effective dates...

  12. 50 CFR 14.108 - Food and water.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Food and water. 14.108 Section 14.108... Wild Mammals and Birds to the United States § 14.108 Food and water. (a) No carrier shall accept any... concerning the animal's food and water requirements are securely affixed to the outside of its primary...

  13. Alternative containment integrity test methods, an overview of possible techniques

    International Nuclear Information System (INIS)

    Spletzer, B.L.

    1986-01-01

    A study is being conducted to develop and analyze alternative methods for testing of containment integrity. The study is focused on techniques for continuously monitoring containment integrity to provide rapid detection of existing leaks, thus providing greater certainty of the integrity of the containment at any time. The study is also intended to develop techniques applicable to the currently required Type A integrated leakage rate tests. A brief discussion of the range of alternative methods currently being considered is presented. The methods include applicability to all major containment types, operating and shutdown plant conditions, and quantitative and qualitative leakage measurements. The techniques are analyzed in accordance with the current state of knowledge of each method. The bulk of the techniques discussed are in the conceptual stage, have not been tested in actual plant conditions, and are presented here as a possible future direction for evaluating containment integrity. Of the methods considered, no single method provides optimum performance for all containment types. Several methods are limited in the types of containment for which they are applicable. The results of the study to date indicate that techniques for continuous monitoring of containment integrity exist for many plants and may be implemented at modest cost

  14. 48 CFR 570.106 - Publicizing/Advertising.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Publicizing/Advertising. 570.106 Section 570.106 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION SPECIAL CONTRACTING PROGRAMS ACQUIRING LEASEHOLD INTERESTS IN REAL PROPERTY General 570.106 Publicizing/Advertising...

  15. Eco-Friendly Alternative Refrigeration Systems

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 6; Issue 10. Eco-Friendly Alternative Refrigeration Systems - Magnetic and ... Author Affiliations. S S Verma1. Deptartment of Physics, Sant Longowal Institute of Engineering and Technology Longowal, District Sangrur, Punjab 148 106, India.

  16. 28 CFR 301.106 - Repetitious accidents.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Repetitious accidents. 301.106 Section 301.106 Judicial Administration FEDERAL PRISON INDUSTRIES, INC., DEPARTMENT OF JUSTICE INMATE ACCIDENT COMPENSATION General § 301.106 Repetitious accidents. If an inmate worker is involved in successive accidents...

  17. 48 CFR 745.106 - Contract clauses.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract clauses. 745.106 Section 745.106 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT GOVERNMENT PROPERTY General 745.106 Contract clauses. (a) The contracting officer shall insert the...

  18. 41 CFR 105-1.106 - Applicability.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Applicability. 105-1.106 Section 105-1.106 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION 1.1-Regulations System § 105-1.106 Applicability...

  19. Alternative Fuels Data Center: North Carolina Transportation Data for

    Science.gov (United States)

    Private Biodiesel (B20 and above) 7 108 Compressed Natural Gas (CNG) 26 16 Electric 500 121 Ethanol (E85 CNG Installation a Boost Aug. 19, 2015 Video thumbnail for Biodiesel Offers an Easy Alternative for Fleets Biodiesel Offers an Easy Alternative for Fleets Aug. 18, 2015 Video thumbnail for Blue Skies

  20. 5 CFR 960.106 - OPM leadership.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false OPM leadership. 960.106 Section 960.106 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EXECUTIVE BOARDS § 960.106 OPM leadership. (a) Role of the Director. The Director is responsible to the...

  1. 7 CFR 900.108 - Mediator's report.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Mediator's report. 900.108 Section 900.108 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Mediator's report. The mediator, upon the completion of mediation proceedings, shall submit to the...

  2. 14 CFR 1213.108 - Multimedia materials.

    Science.gov (United States)

    2010-01-01

    ....108 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RELEASE OF INFORMATION TO NEWS AND INFORMATION MEDIA § 1213.108 Multimedia materials. (a) NASA's multimedia material, from all... will provide the media, the public, and as necessary, NASA Headquarters with: (1) Selected prints and...

  3. Phosphorylation of Rac1 T108 by Extracellular Signal-Regulated Kinase in Response to Epidermal Growth Factor: a Novel Mechanism To Regulate Rac1 Function

    Science.gov (United States)

    Tong, Junfeng; Li, Laiji; Ballermann, Barbara

    2013-01-01

    Accumulating evidence has implicated Rho GTPases, including Rac1, in many aspects of cancer development. Recent findings suggest that phosphorylation might further contribute to the tight regulation of Rho GTPases. Interestingly, sequence analysis of Rac1 shows that Rac1 T108 within the 106PNTP109 motif is likely an extracellular signal-regulated kinase (ERK) phosphorylation site and that Rac1 also has an ERK docking site, 183KKRKRKCLLL192 (D site), at the C terminus. Indeed, we show here that both transfected and endogenous Rac1 interacts with ERK and that this interaction is mediated by its D site. Green fluorescent protein (GFP)-Rac1 is threonine (T) phosphorylated in response to epidermal growth factor (EGF), and EGF-induced Rac1 threonine phosphorylation is dependent on the activation of ERK. Moreover, mutant Rac1 with the mutation of T108 to alanine (A) is not threonine phosphorylated in response to EGF. In vitro ERK kinase assay further shows that pure active ERK phosphorylates purified Rac1 but not mutant Rac1 T108A. We also show that Rac1 T108 phosphorylation decreases Rac1 activity, partially due to inhibiting its interaction with phospholipase C-γ1 (PLC-γ1). T108 phosphorylation targets Rac1 to the nucleus, which isolates Rac1 from other guanine nucleotide exchange factors (GEFs) and hinders Rac1's role in cell migration. We conclude that Rac1 T108 is phosphorylated by ERK in response to EGF, which plays an important role in regulating Rac1. PMID:24043306

  4. 29 CFR 1614.106 - Individual complaints.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Individual complaints. 1614.106 Section 1614.106 Labor... EMPLOYMENT OPPORTUNITY Agency Program To Promote Equal Employment Opportunity § 1614.106 Individual... individual and the agency and to describe generally the action(s) or practice(s) that form the basis of the...

  5. 7 CFR 3550.106 - Dwelling requirements.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Dwelling requirements. 3550.106 Section 3550.106... Waste Disposal Grants § 3550.106 Dwelling requirements. (a) Modest dwelling. The property must be one... § 3550.63. (b) Post-repair condition. Dwellings repaired with section 504 funds need not be brought to...

  6. 34 CFR 106.33 - Comparable facilities.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Comparable facilities. 106.33 Section 106.33 Education... Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 106.33 Comparable facilities. A recipient may provide separate toilet, locker room, and shower facilities on the basis of sex, but...

  7. 20 CFR 718.106 - Autopsy; biopsy.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Autopsy; biopsy. 718.106 Section 718.106... PNEUMOCONIOSIS Criteria for the Development of Medical Evidence § 718.106 Autopsy; biopsy. (a) A report of an autopsy or biopsy submitted in connection with a claim shall include a detailed gross macroscopic and...

  8. 19 CFR 152.106 - Computed value.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Computed value. 152.106 Section 152.106 Customs... (CONTINUED) CLASSIFICATION AND APPRAISEMENT OF MERCHANDISE Valuation of Merchandise § 152.106 Computed value. (a) Elements. The computed value of imported merchandise is the sum of: (1) The cost or value of the...

  9. IRIG 106 Chapter 10 Programmers Handbook

    Science.gov (United States)

    2016-08-16

    szDataItem. Specific parsers are called for specific attribute types, indicated by the first letter of the code name. After all TMATS attributes are...EnI106Status I106_CALL_DECL enI106Ch10Close(int iHandle) { // If handles have been init’ed then bail if

  10. 9 CFR 3.106 - Water quality.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Water quality. 3.106 Section 3.106... Mammals Animal Health and Husbandry Standards § 3.106 Water quality. (a) General. The primary enclosure... additives (e.g. chlorine and copper) that are added to the water to maintain water quality standards...

  11. 34 CFR 300.108 - Physical education.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Physical education. 300.108 Section 300.108 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION ASSISTANCE TO STATES FOR THE EDUCATION OF CHILDREN WITH...

  12. 13 CFR 108.692 - Examination fees.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Examination fees. 108.692 Section...NMVCâ) PROGRAM Recordkeeping, Reporting, and Examination Requirements for NMVC Companies Examinations of Nmvc Companies by Sba for Regulatory Compliance § 108.692 Examination fees. (a) General. SBA will...

  13. 33 CFR 101.125 - Approved Alternative Security Programs.

    Science.gov (United States)

    2010-07-01

    ... 106 of this subchapter, as applicable: (a) American Gaming Association Alternative Security Program..., and Towboats and Barges, dated September 24, 2003. (c) Passenger Vessel Association Industry Standards...

  14. Nuclear power and the possibility of alternative fuel cycles

    International Nuclear Information System (INIS)

    Engelmann, P.

    1979-01-01

    Concern about the societal implications, potential risks and the possibility of nuclear weapons proliferation has slowed down the growth of nuclear energy. Assuming a further moderate growth of nuclear power in the Federal Republic of Germany several fuel cycle and reactor strategies can the followed without exhausting the nuclear the resources before the year 2100. The uranium demand of various reactor strategies with LWR's FBR's and HTR's is compared for two demand cases in the FRG. While recycling of spent fuel seems necessary in any case, it is shown that the Th/U cycle can provide a realistic alternative to the U/Pu cycle. The parallel introduction of both cycles appears as the best solution, as it reduces the overall risks and leads to minimum uranium demand. The risk of nuclear proliferation does not vary considerably with the fuel cycle applied; it can, however, be reduced to acceptable levels by safeguards methods and institutional means. (orig.) [de

  15. 48 CFR 7.108 - Additional requirements for telecommuting.

    Science.gov (United States)

    2010-10-01

    ... for telecommuting. 7.108 Section 7.108 Federal Acquisition Regulations System FEDERAL ACQUISITION... telecommuting. In accordance with section 1428 of Public Law 108-136, an agency shall generally not discourage a... the agency, including security requirements, cannot be met if telecommuting is permitted. The...

  16. 46 CFR 108.503 - Relationship to international standards.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Relationship to international standards. 108.503 Section 108.503 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Lifesaving Equipment § 108.503 Relationship to international standards. For...

  17. 34 CFR 108.6 - Equal access.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Equal access. 108.6 Section 108.6 Education Regulations of the Offices of the Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION EQUAL... limited to, school-related means of communication, such as bulletin board notices and literature...

  18. 46 CFR 108.487 - Helicopter deck fueling operations.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Helicopter deck fueling operations. 108.487 Section 108... DESIGN AND EQUIPMENT Fire Extinguishing Systems Fire Protection for Helicopter Facilities § 108.487 Helicopter deck fueling operations. (a) Each helicopter landing deck on which fueling operations are...

  19. 46 CFR 108.645 - Markings on lifesaving appliances.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Markings on lifesaving appliances. 108.645 Section 108.645 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Equipment Markings and Instructions § 108.645 Markings on lifesaving appliances. (a...

  20. 46 CFR 108.665 - Appliances for watertight integrity.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Appliances for watertight integrity. 108.665 Section 108.665 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Equipment Markings and Instructions § 108.665 Appliances for watertight integrity...

  1. 12 CFR 347.106 - Going concerns.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Going concerns. 347.106 Section 347.106 Banks... INTERNATIONAL BANKING § 347.106 Going concerns. Going concerns. If a bank acquires an equity interest in a foreign organization that is a going concern, no more than 5 percent of either the consolidated assets or...

  2. Separation of fission produced 106Ru from simulated high level nuclear wastes for production of brachytherapy sources

    International Nuclear Information System (INIS)

    Blicharska, Magdalena; Bartoś, Barbara; Krajewski, Seweryn; Bilewicz, Aleksander

    2014-01-01

    Brachytherapy is the common method for treating various tumors, and currently 106 Ru and 125 I applicators are the most frequently used. Considering that 106 Ru is a β emitter with maximum energy of 3.54 MeV, it is best indicated in the treatment of small melanomas, with up to 20 mm tissue range. 106 Ru is commercially obtained from neutron irradiated high enrichment 235 U target in process of production 99 Mo. At present, there are only a handful of ageing reactors worldwide capable of producing the 99 Mo, therefore alternative strategies for production of this key medical isotope are explored. In our work, we propose to use liquid high-level radioactive waste as a source of high activity of 106 Ru. Simple calculations indicate that 1 dm 3 of HLLW solution after 4 years of cooling contains about 500 GBq of 106 Ru. This amount of activity is enough for production of about few thousands of brachytherapy sources. Present communication reports results of our process development studies on the recovery of ruthenium radioisotopes from simulated solution of high level radioactive waste using oxidation-extraction method

  3. 46 CFR 108.530 - Stowage of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Stowage of survival craft. 108.530 Section 108.530... AND EQUIPMENT Lifesaving Equipment § 108.530 Stowage of survival craft. (a) General. Each survival craft required to be served by a launching appliance or marine evacuation system must be stowed as...

  4. 21 CFR 108.25 - Acidified foods.

    Science.gov (United States)

    2010-04-01

    ... Administration on Form FDA 2541 (food canning establishment registration) information including, but not limited... continuous inspection of the meat and poultry inspection program of the Food Safety and Inspection Service of... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Acidified foods. 108.25 Section 108.25 Food and...

  5. Nonradioactive air emissions notice of construction, Project W-320, 241-C-106 tank sluicing

    International Nuclear Information System (INIS)

    Hays, C.B.

    1998-01-01

    This document serves as a Notice of Construction for the Phase 2 activities of Project W-320, 241-C-106 Tank Sluicing, pursuant to the requirements of Washington Administrative Codes (WAC) 173-400 and 173-460. Phased permitting for Project W-320 was discussed with the Washington State Department of Ecology (Ecology) on November 2, 1993. In April 1994, it was deemed unnecessary because the Phase 1 activities did not constitute a new source of emissions and therefore did not require approval from Ecology. The 241-C-106 tank is a 2-million liter capacity, single-shell tank (SST) used for radioactive waste storage since 1947. Between mid-1963 and mid-1969, 241-C-106 tank received high-heat waste, PUREX (plutonium-uranium extraction) Facility high-level waste, and strontium-bearing solids from the strontium and cesium recovery activities. In 1971, temperatures exceeding 99 C were observed in the tank, and therefore, a ventilation system was installed to cool the tank. In addition, approximately 22,712 liters of cooling water are added to the tank each month to prevent the sludge from drying out and overheating. Excessive drying of the sludge could result in possible structural damage. The current radiolytic heat generation rate has been calculated at 32 kilowatts (kW) plus or minus 6 kW. The 241-C-106 tank was withdrawn from service in 1979 and currently is categorized as not leaking. The heat generation in 241-C-106 tank has been identified as a key safety issue on the Hanford Site. The evaporative cooling provided by the added water during operation and/or sluicing maintains the 241-C-106 tank within its specified operating temperature limits. Project W-320, 241-C-106 Tank Sluicing, will mobilize and remove the heat-generating sludge, allowing the water additions to cease. Following sludge removal, the 241-C-106 tank could be placed in a safe, interim stabilized condition. Tank-to-tank sluicing, an existing, proven technology, will provide the earliest possible

  6. Nonradioactive air emissions notice of construction, Project W-320, 241-C-106 tank sluicing

    Energy Technology Data Exchange (ETDEWEB)

    Hays, C.B.

    1998-01-28

    This document serves as a Notice of Construction for the Phase 2 activities of Project W-320, 241-C-106 Tank Sluicing, pursuant to the requirements of Washington Administrative Codes (WAC) 173-400 and 173-460. Phased permitting for Project W-320 was discussed with the Washington State Department of Ecology (Ecology) on November 2, 1993. In April 1994, it was deemed unnecessary because the Phase 1 activities did not constitute a new source of emissions and therefore did not require approval from Ecology. The 241-C-106 tank is a 2-million liter capacity, single-shell tank (SST) used for radioactive waste storage since 1947. Between mid-1963 and mid-1969, 241-C-106 tank received high-heat waste, PUREX (plutonium-uranium extraction) Facility high-level waste, and strontium-bearing solids from the strontium and cesium recovery activities. In 1971, temperatures exceeding 99 C were observed in the tank, and therefore, a ventilation system was installed to cool the tank. In addition, approximately 22,712 liters of cooling water are added to the tank each month to prevent the sludge from drying out and overheating. Excessive drying of the sludge could result in possible structural damage. The current radiolytic heat generation rate has been calculated at 32 kilowatts (kW) plus or minus 6 kW. The 241-C-106 tank was withdrawn from service in 1979 and currently is categorized as not leaking. The heat generation in 241-C-106 tank has been identified as a key safety issue on the Hanford Site. The evaporative cooling provided by the added water during operation and/or sluicing maintains the 241-C-106 tank within its specified operating temperature limits. Project W-320, 241-C-106 Tank Sluicing, will mobilize and remove the heat-generating sludge, allowing the water additions to cease. Following sludge removal, the 241-C-106 tank could be placed in a safe, interim stabilized condition. Tank-to-tank sluicing, an existing, proven technology, will provide the earliest possible

  7. 46 CFR 108.520 - Type of survival craft.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Type of survival craft. 108.520 Section 108.520 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Lifesaving Equipment § 108.520 Type of survival craft. (a) Each lifeboat must be a fire-protected...

  8. 31 CFR 10.8 - Customhouse brokers.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Customhouse brokers. 10.8 Section 10... REVENUE SERVICE Rules Governing Authority to Practice § 10.8 Customhouse brokers. Nothing contained in the regulations in this part will affect or limit the right of a customhouse broker, licensed as such by the...

  9. Estimates of relative doses of {sup 106}Ru/{sup 106}Rh of spherical applicators used in ophthalmic brachytherapy; Estimativas de doses relativas de aplicadores esfericos de {sup 106}Ru/{sup 106}Rh usados em braquiterapia oftalmologica

    Energy Technology Data Exchange (ETDEWEB)

    Paiva, Eduardo de, E-mail: edup2112@gmail.com, E-mail: epaiva@ird.gov.br [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil). Div. de Fisica Medica

    2016-11-01

    Spherical ophthalmic applicators containing the beta emitter {sup 106}Ru / {sup 106}Rh are much used in brachytherapy for the treatment of various eye diseases. However, there is great difficulty in dosimetry these sources because of its geometric shape, the short range of the beta particles and the large dose gradient, and because of that calculation methods of dose distributions around these sources take on a great importance. In this work an analytical / numerical method is used to estimate the dose rates for a function of depth for spherical sources containing {sup 106}Ru / {sup 106}Rh. The results of the doses on along the central axis for applicators models CXS, CCX, CCY, CCZ, CCD and CGD and CCC are compared with published values calculated by Monte Carlo simulation and measurement results.

  10. 29 CFR 779.108 - Goods produced for commerce.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Goods produced for commerce. 779.108 Section 779.108 Labor... Coverage Employees Engaged in Commerce Or in the Production of Goods for Commerce § 779.108 Goods produced for commerce. Goods are “produced for commerce” if they are “produced, manufactured, mined, handled or...

  11. Heat transfer performance of the OPAC 106 heat exchanger; Warmte-overdrachtsprestaties van de OPAC106 warmtewisselaar

    Energy Technology Data Exchange (ETDEWEB)

    De Zwart, H.F.; Janssen, H.J.J. [Wageningen UR Glastuinbouw, Wageningen (Netherlands)

    2010-10-15

    The heat transfer performance of a new type compact heat exchanger were studied. It concerns the OPAC106, developed for the horticultural sector. The OPAC 106 combines a compact size with high heat transfer at low consumption of electricity for air circulation. OPAC stands for Oval Pipe Air Conditioner [Dutch] De warmte-overdrachtprestaties van een nieuw type compacte warmtewisselaar zijn bestudeerd. Het betreft de OPAC106, een speciaal voor de tuinbouw ontwikkelde warmtewisselaar. OPAC betekent Ovale Pijpen Air Conditioner.

  12. 34 CFR 106.59 - Advertising.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Advertising. 106.59 Section 106.59 Education Regulations of the Offices of the Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION... Advertising. A recipient shall not in any advertising related to employment indicate preference, limitation...

  13. 34 CFR 106.53 - Recruitment.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Recruitment. 106.53 Section 106.53 Education... Recruitment. (a) Nondiscriminatory recruitment and hiring. A recipient shall not discriminate on the basis of sex in the recruitment and hiring of employees. Where a recipient has been found to be presently...

  14. 13 CFR 106.101 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... legal consideration. (i) Non-Fee Based SBA-Sponsored Activity Record (Non-Fee Based Record) means a... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Definitions. 106.101 Section 106.101 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION COSPONSORSHIPS, FEE AND NON-FEE BASED...

  15. 42 CFR 66.106 - Awards.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Awards. 66.106 Section 66.106 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL... program leading to the degrees of doctor of medicine and doctor of philosophy. [48 FR 24880, June 3, 1983...

  16. 49 CFR 230.106 - Steam locomotive frame.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Steam locomotive frame. 230.106 Section 230.106... Tenders Trucks, Frames and Equalizing System § 230.106 Steam locomotive frame. (a) Maintenance and inspection. Frames, decks, plates, tailpieces, pedestals, and braces shall be maintained in a safe and...

  17. 18 CFR 284.103-284.106 - [Reserved

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false [Reserved] 284.103-284.106 Section 284.103-284.106 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... RELATED AUTHORITIES Certain Transportation by Interstate Pipelines §§ 284.103-284.106 [Reserved] ...

  18. 7 CFR 4280.106 - Conflict of interest.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Conflict of interest. 4280.106 Section 4280.106... Efficiency Improvements Program § 4280.106 Conflict of interest. No conflict of interest or appearance of conflict of interest will be allowed. For purposes of this subpart, conflict of interest includes, but is...

  19. 33 CFR 106.415 - Amendment and audit.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Amendment and audit. 106.415 Section 106.415 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY MARITIME SECURITY MARINE SECURITY: OUTER CONTINENTAL SHELF (OCS) FACILITIES Outer Continental Shelf (OCS) Facility Security Plan (FSP) § 106.415 Amendment and...

  20. 13 CFR 108.740 - Portfolio diversification (“overline” limitation).

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Portfolio diversification (âoverlineâ limitation). 108.740 Section 108.740 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION... Determining the Eligibility of A Small Business for Nmvc Financing § 108.740 Portfolio diversification...

  1. 41 CFR 101-25.108 - Multiyear subscriptions for publications.

    Science.gov (United States)

    2010-07-01

    ... for publications. 101-25.108 Section 101-25.108 Public Contracts and Property Management Federal...-GENERAL 25.1-General Policies § 101-25.108 Multiyear subscriptions for publications. Subscriptions for periodicals, newspapers, and other publications for which it is known in advance that a continuing requirement...

  2. 19 CFR 360.108 - Loss of electronic licensing privileges.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Loss of electronic licensing privileges. 360.108 Section 360.108 Customs Duties INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE STEEL IMPORT MONITORING AND ANALYSIS SYSTEM § 360.108 Loss of electronic licensing privileges. Should Commerce determine...

  3. 9 CFR 108.11 - Water quality requirements.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Water quality requirements. 108.11... LICENSED ESTABLISHMENTS § 108.11 Water quality requirements. A certification from the appropriate water pollution control agency, that the establishment is in compliance with applicable water quality control...

  4. 14 CFR 1245.108 - License to contractor.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false License to contractor. 1245.108 Section... INTELLECTUAL PROPERTY RIGHTS Patent Waiver Regulations § 1245.108 License to contractor. (a) Each contractor.... The license extends to the contractor's domestic subsidiaries and affiliates, if any, within the...

  5. High-level waste leakage from the 241-T-106 tank at Hanford

    International Nuclear Information System (INIS)

    Routson, R.C.; Price, W.H.; Brown, D.J.; Fecht, K.R.

    1979-02-01

    The history, status, fate, and impact of the 4.34 x 10 5 -liter (115,000-gal) radioactive waste tank leak from the 241-T-106 tank have been studied since 1973. As of May 1978, the maximum detected depth of the 1-microcurie per liter (μCi/l) concentration of 106 Ru penetration was 33 meters (108 ft) below the ground surface or 29 meters (95 ft) above the regional water table. This maximum depth of penetration was detected in two of the dry wells in the 241-T tank farm. In no other well has radioactivity greater than 1.0-μCi/l been found deeper than 29 meters (95 ft). This is approximately 43% of the distance from the bottom of the tank to the water table. The maximum horizontal movement of the 1-μCi/l 106 Ru concentration front from the tank was approximately 23 meters (75 ft) at a depth of 25 meters (82 ft). This distance is approximately equal to the diameter of the tank. The rate of frontal movement of radioactivity was qualitatively estimated. A large portion of the movement occurred in 1973, prior to the publication of an initial tank leak status report. From 1973 to 1974, detectable lateral movement occurred in at least some sediment layers. From 1974 to 1978, movement could not generally be detected. However, migration in wells near the leak perimeter was detected in 1978, and the probable cause defined. Calculations on vadose zone moisture and wetting frontal movement were found to be essentially in qualitative agreement in their assessed lack of movement of any waste above concentration guidelines to the Hanford ground water. Thus, during the hazardous lifetime of the fission products, there will likely be no amount of radioactivity enter the Hanford ground water. Therefore, there appears to be no impact of the leak on the Columbia River

  6. 42 CFR 460.106 - Plan of care.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Plan of care. 460.106 Section 460.106 Public Health... ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PROGRAMS OF ALL-INCLUSIVE CARE FOR THE ELDERLY (PACE) PACE Services § 460.106 Plan of care. (a) Basic requirement. The interdisciplinary team must promptly develop a...

  7. 46 CFR 108.404 - Selection of fire detection system.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Selection of fire detection system. 108.404 Section 108... DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.404 Selection of fire detection system. (a) If a... space. (b) The fire detection system must be designed to minimize false alarms. ...

  8. 28 CFR 34.108 - Selection of reviewers.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Selection of reviewers. 34.108 Section 34.108 Judicial Administration DEPARTMENT OF JUSTICE OJJDP COMPETITION AND PEER REVIEW PROCEDURES Peer... by the Administrator. The selection process for peer reviewers is detailed in the OJJDP “Peer Review...

  9. Permitting plan for Project W-340, Tank 241-C-106 manipulator retrieval arm

    International Nuclear Information System (INIS)

    Tollefson, K.S.

    1995-01-01

    This document describes the regulatory requirements and describes alternative strategies for obtaining permits and approvals for Project W-340, Tank 241-C-106 Manipulator Retrieval Arm. A comprehensive review of environmental regulations has indicated that several environmental reviews, permits, and approvals are required before design, construction, and operation of the facility. The environmental reviews, permits, and approvals, as well the regulatory authority potentially applicable to the Project W-340 Long Reach Manipulator Arm include the following: National Environmental Policy Act of 1969 -- US Department of Energy, Headquarters; State Environmental Policy Act of 1971 -- State of Washington Department of Ecology; Air Permitting; Dangerous Waste Permitting; Miscellaneous Reviews/Permits/Approvals. This document describes the environmental reviews, permits, and approval requirements for the project. It provides a summary of permit application data requirements, alternative strategies for permit completion and approval, as well as the estimated probability of success for each alternative strategy

  10. Effect of valine 106 on structure-function relation of cytosolic human thymidine kinase - Kinetic properties and oligomerization pattern of nine substitution mutants of V106

    DEFF Research Database (Denmark)

    Frederiksen, Hanne; Berenstein, Dvora; Munch-Petersen, Birgitte

    2004-01-01

    Information on the regulation and structure-function relation of enzymes involved in DNA precursor synthesis is pivotal, as defects in several of these enzymes have been found to cause depletion or deletion of mitochondrial DNA resulting in severe diseases. Here, the effect of amino acid 106...... and characterized nine mutants of amino acid 106 differing in size, conformation and polarity. According to their oligomerization pattern and thymidine kinetics, the TK1 mutants can be divided into two groups. Group I (V106A, V106I and V106T) behaves like V106WT, in that pre-assay exposure to ATP induces reversible...... transition from a dimer with low catalytic activity to a tetramer with high catalytic activity. Group II (V106G, V106H, V106K, V106L and V106Q) behaves like V106M in that they are permanently high activity tetramers, irrespective of ATP exposure. We conclude that size and conformation of amino acid 106...

  11. 20 CFR 726.106 - Type of security.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Type of security. 726.106 Section 726.106... Authorization of Self-Insurers § 726.106 Type of security. (a) The Office shall determine the type or types of... which the surety on any such bond is a surety company, such company must be one approved by the U.S...

  12. 13 CFR 108.200 - Adequate capital for NMVC Companies.

    Science.gov (United States)

    2010-01-01

    ... VENTURE CAPITAL (âNMVCâ) PROGRAM Qualifications for the NMVC Program Capitalizing A Nmvc Company § 108.200 Adequate capital for NMVC Companies. You must meet the requirements of §§ 108.200-108.230 in order to... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Adequate capital for NMVC...

  13. Modeling of action potential generation in NG108-15 cells.

    Science.gov (United States)

    Molnar, Peter; Hickman, James J

    2014-01-01

    In order to explore the possibility of identifying toxins based on their effect on the shape of action potentials, we created a computer model of the action potential generation in NG108-15 cells (a neuroblastoma/glioma hybrid cell line). To generate the experimental data for model validation, voltage-dependent sodium, potassium and high-threshold calcium currents, as well as action potentials, were recorded from NG108-15 cells with conventional whole-cell patch-clamp methods. Based on the classic Hodgkin-Huxley formalism and the linear thermodynamic description of the rate constants, ion-channel parameters were estimated using an automatic fitting method. Utilizing the established parameters, action potentials were generated using the Hodgkin-Huxley formalism and were fitted to the recorded action potentials. To demonstrate the applicability of the method for toxin detection and discrimination, the effect of tetrodotoxin (a sodium channel blocker) and tefluthrin (a pyrethroid that is a sodium channel opener) were studied. The two toxins affected the shape of the action potentials differently, and their respective effects were identified based on the predicted changes in the fitted parameters.

  14. Chemical composition of stars in Ruprecht 106 .

    Science.gov (United States)

    François, P.

    High resolution spectra of 9 stars belonging to the globular cluster Rup 106 have been used to determine their chemical composition. The results reveal that Ruprecht 106 exhibits abundance anomalies when compared to galactic globular cluster of similar metallicity. The chemical composition of these stars is similar to what is found in Dwarf spheroidal galaxies favoring the hypothesis that Rup 106 has not been formed in our Galaxy.

  15. 48 CFR 9.106-4 - Reports.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Reports. 9.106-4 Section 9... CONTRACTOR QUALIFICATIONS Responsible Prospective Contractors 9.106-4 Reports. (a) The surveying activity... performance. The narrative shall report any persistent pattern of need for costly and burdensome Government...

  16. 38 CFR 17.106 - Authority for disciplinary action.

    Science.gov (United States)

    2010-07-01

    ... disciplinary action. 17.106 Section 17.106 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Disciplinary Control of Beneficiaries Receiving Hospital, Domiciliary Or Nursing Home Care § 17.106 Authority for disciplinary action. The good conduct of beneficiaries receiving hospitalization...

  17. Third cumulative index for Koedoe: volumes 35/2-44/1

    Directory of Open Access Journals (Sweden)

    J.C. Rautenbach

    2001-07-01

    • 104 Mammalia • 104 Archaeology and History • 105 Bibliography • 106 Climate • 106 Geologyand Pedology • 106 Environmental impact on rivers & water quality • 106 Check list • 107 Issues in conservation • 107 Maps • 108 Social Science • 108 Parks

  18. 5 CFR 9701.106 - Relationship to other provisions.

    Science.gov (United States)

    2010-01-01

    ....106 Section 9701.106 Administrative Personnel DEPARTMENT OF HOMELAND SECURITY HUMAN RESOURCES... SECURITY HUMAN RESOURCES MANAGEMENT SYSTEM General Provisions § 9701.106 Relationship to other provisions....S.C. 5545(d); (iv) Recruitment, relocation, and retention payments under 5 U.S.C. 5753-5754; (v...

  19. 34 CFR 106.56 - Fringe benefits.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Fringe benefits. 106.56 Section 106.56 Education... benefits. (a) Fringe benefits defined. For purposes of this part, fringe benefits means: Any medical, hospital, accident, life insurance or retirement benefit, service, policy or plan, any profit-sharing or...

  20. An alternative solver for the nodal expansion method equations - 106

    International Nuclear Information System (INIS)

    Carvalho da Silva, F.; Carlos Marques Alvim, A.; Senra Martinez, A.

    2010-01-01

    An automated procedure for nuclear reactor core design is accomplished by using a quick and accurate 3D nodal code, aiming at solving the diffusion equation, which describes the spatial neutron distribution in the reactor. This paper deals with an alternative solver for nodal expansion method (NEM), with only two inner iterations (mesh sweeps) per outer iteration, thus having the potential to reduce the time required to calculate the power distribution in nuclear reactors, but with accuracy similar to the ones found in conventional NEM. The proposed solver was implemented into a computational system which, besides solving the diffusion equation, also solves the burnup equations governing the gradual changes in material compositions of the core due to fuel depletion. Results confirm the effectiveness of the method for practical purposes. (authors)

  1. 27 CFR 28.106 - Consignment, shipment, and delivery.

    Science.gov (United States)

    2010-04-01

    ... delivery. 28.106 Section 28.106 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... Transportation to a Manufacturing Bonded Warehouse § 28.106 Consignment, shipment, and delivery. The consignment, shipment, and delivery of distilled spirits withdrawn without payment of tax under this subpart shall be...

  2. 13 CFR 108.504 - Equipment and office requirements.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Equipment and office requirements. 108.504 Section 108.504 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS... convenient to the public and is open for business during normal working hours. ...

  3. Project W-340 tank 241-C-106 manipulator system closeout summary

    International Nuclear Information System (INIS)

    McDaniel, L.B.

    1995-02-01

    This document summarizes the work that was ongoing when Project W-340 was put on hold. Project W-340: Tank 241-C-106 Manipulator Retrieval System, was a candidate FY98 Major System Acquisition. The project was to develop, procure and deploy a Long Reach Manipulator (LRM) waste retrieval system to provide an alternate method to completing the in-tank demonstration of Single Shell Tank waste retrieval technology. The need for enhanced capabilities derives from (1) the inability of the baseline technology to retrieve certain hard waste forms; (2) uncertainty in the quantity of leakage which will be allowed. Numerous studies over the years have identified an arm architecture as a promising retrieval technology to overcome these concerns. The W340 project was intended to further develop and demonstrate this alternative, as part of selecting the best approach for all tanks. Prior to completing the effort, it was determined that an LRM system was too architecture specific and was envisioned to be too expensive for a one time demonstration of retrieval technology. At the time the work was stopped, an effort was underway to broaden the project scope to allow alternatives to an arm-based system

  4. 49 CFR 106.10 - Process for issuing rules.

    Science.gov (United States)

    2010-10-01

    ... filing written comments or making oral presentations). (4) Whom to call if you have questions about the... 49 Transportation 2 2010-10-01 2010-10-01 false Process for issuing rules. 106.10 Section 106.10... PHMSA Rulemaking Documents § 106.10 Process for issuing rules. (a) PHMSA (“we”) uses informal rulemaking...

  5. 13 CFR 108.120 - Economic development primary mission.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Economic development primary mission. 108.120 Section 108.120 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS... Economic development primary mission. The primary mission of a NMVC Company must be economic development of...

  6. 34 CFR 106.55 - Job classification and structure.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Job classification and structure. 106.55 Section 106.55 Education Regulations of the Offices of the Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF... Prohibited § 106.55 Job classification and structure. A recipient shall not: (a) Classify a job as being for...

  7. Well drilling summary report for well 199-N-106A

    International Nuclear Information System (INIS)

    Walker, L.D.

    1996-02-01

    Past liquid waste disposal practices within the 100-N Area have resulted in the contamination of the underlying sediments and groundwater. The release of large volumes of liquid effluent to the 1301-N and 1325-N Liquid Waste Disposal Facilities caused the transport of 90 Sr and other contaminants to the groundwater. Further discussion of 100-N Area hydrogeology is provided in Hartman and Lindsey (1993). A pump-and-treat system combined with a vertical barrier is the preferred alternative for the N Springs Expedited Response Action. This document is a compilation of the data collected during the drilling of well 199-N-106A, an extraction well for the 100-N Pump-and-Treat Project

  8. 46 CFR 108.223 - Guards on exposed equipment.

    Science.gov (United States)

    2010-10-01

    ... have hand covers, guards, or rails installed on all belts, gears, shafts, pulleys, sprockets, spindles... 46 Shipping 4 2010-10-01 2010-10-01 false Guards on exposed equipment. 108.223 Section 108.223 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN...

  9. 7 CFR 3550.108 - Security requirements (loans only).

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Security requirements (loans only). 3550.108 Section..., DEPARTMENT OF AGRICULTURE DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Section 504 Origination and Section 306C Water and Waste Disposal Grants § 3550.108 Security requirements (loans only). When the total...

  10. Energy deposition by a 106Ru/106Rh eye applicator simulated using LEPTS, a low-energy particle track simulation

    International Nuclear Information System (INIS)

    Fuss, M.C.; Munoz, A.; Oller, J.C.; Blanco, F.; Williart, A.; Limao-Vieira, P.; Borge, M.J.G.; Tengblad, O.; Huerga, C.; Tellez, M.; Garcia, G.

    2011-01-01

    The present study introduces LEPTS, an event-by-event Monte Carlo programme, for simulating an ophthalmic 106 Ru/ 106 Rh applicator relevant in brachytherapy of ocular tumours. The distinctive characteristics of this code are the underlying radiation-matter interaction models that distinguish elastic and several kinds of inelastic collisions, as well as the use of mostly experimental input data. Special emphasis is placed on the treatment of low-energy electrons for generally being responsible for the deposition of a large portion of the total energy imparted to matter. - Highlights: → We present the Monte Carlo code LEPTS, a low-energy particle track simulation. → Carefully selected input data from 10 keV to 1 eV. → Application to an electron emitting Ru-106/Rh-106 plaque used in brachytherapy.

  11. 11 CFR 108.8 - Exemption for the District of Columbia.

    Science.gov (United States)

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Exemption for the District of Columbia. 108.8 Section 108.8 Federal Elections FEDERAL ELECTION COMMISSION GENERAL FILING COPIES OF REPORTS AND STATEMENTS WITH STATE OFFICERS (2 U.S.C. 439) § 108.8 Exemption for the District of Columbia. Any copy of a...

  12. [The law of quotas for people with disabilities in Brazilian companies: the impact and possible alternatives].

    Science.gov (United States)

    Zanitelli, Leandro Martins

    2013-07-01

    This paper consists of a theoretical analysis of the impact of the Brazilian law establishing quotas for people with disabilities in companies with one hundred or more employees, as well as the possible impact of some alternative legal measures: incentives (fiscal incentives and tradable rights) and information disclosure policies. The analysis is based on work regarding the efficacy of legal norms in general, and particularly the literature concerning the cost and cognitive effects of those norms. Given its exclusively theoretical character, the paper does not affirm the superiority of any regulatory strategy over the current law, but draws attention to the likely reasons for the failure of the quota system and for the potential and inconveniences of its proposed alternatives.

  13. NEW PRECISION ORBITS OF BRIGHT DOUBLE-LINED SPECTROSCOPIC BINARIES. III. HD 82191, ω DRACONIS, AND 108 HERCULIS

    International Nuclear Information System (INIS)

    Fekel, Francis C.; Williamson, Michael H.; Tomkin, Jocelyn

    2009-01-01

    We have determined improved spectroscopic orbits for three double-lined binaries, HD 82191 (Am), ω Dra (F5 V), and 108 Her (Am), using radial velocities from the 2.1 m telescope at McDonald Observatory, the coude feed telescope at Kitt Peak National Observatory, and 2 m telescope at Fairborn Observatory. The orbital periods range from 5.28 to 9.01 days, and all three systems have circular orbits. The new orbital dimensions (a 1 sin i and a 2 sin i) and minimum masses (m 1 sin 3 i and m 2 sin 3 i) have accuracies of 0.2% or better. Our improved results confirm the large minimum masses of HD 82191 and also agree with the values previously found for ω Dra. However, for the components of 108 Her our minimum masses are about 20% larger than the previous best values. We conclude that both components of HD 82191 as well as the primary of 108 Her are Am stars. However, the A9 secondary of 108 Her has normal abundances. We estimate spectral types of F4 dwarf and G0 dwarf for the components of ω Dra. The primaries of the three binaries are synchronously rotating as is the secondary of 108 Her. The secondaries of HD 82191 and ω Dra are possibly synchronously rotating.

  14. 13 CFR 108.2007 - Grant award to SSBICs.

    Science.gov (United States)

    2010-01-01

    ... Section 108.2007 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL... receive a grant award only if, by a date established by SBA, it increases its Regulatory Capital in the specific amount set forth in its application, pursuant to § 108.2004(a), and raises matching resources for...

  15. 27 CFR 21.106 - Diethyl phthalate.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Diethyl phthalate. 21.106....106 Diethyl phthalate. (a) Refractive index at 25 °C. 1.497 to 1.502. (b) Color. Colorless. (c) Odor... °/25 °C. 1.115 to 1.118. (f) Ester content (as diethyl phthalate). Not less than 99 percent by weight...

  16. 13 CFR 108.506 - Safeguarding the NMVC Company's assets/Internal controls.

    Science.gov (United States)

    2010-01-01

    ... assets/Internal controls. 108.506 Section 108.506 Business Credit and Assistance SMALL BUSINESS... Requirements § 108.506 Safeguarding the NMVC Company's assets/Internal controls. You must adopt a plan to... document describing your control procedures. ...

  17. Instrument air dew point requirements -- 108-P, L, K

    International Nuclear Information System (INIS)

    Fairchild, P.N.

    1994-01-01

    The 108 Building dew point analyzers measure dew point at atmospheric pressure. Existing 108 Roundsheets state the maximum dew point temperature shall be less than -50 F. After repeatedly failing to maintain a -50 F dew point temperature Reactor Engineering researched the basis for the existing limit. This report documents the results of the study and provides technical justification for a new maximum dew point temperature of -35 F at atmospheric pressure as read by the 108 building dew point analyzers

  18. 13 CFR 108.10 - Description of the New Markets Venture Capital Program.

    Science.gov (United States)

    2010-01-01

    ... Venture Capital Program. 108.10 Section 108.10 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL (âNMVCâ) PROGRAM Introduction to Part 108 § 108.10 Description of the New Markets Venture Capital Program. The New Markets Venture Capital (“NMVC”) Program is a...

  19. 9 CFR 108.3 - Preparation of plot plans.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Preparation of plot plans. 108.3... LICENSED ESTABLISHMENTS § 108.3 Preparation of plot plans. Plot plans shall show all of the buildings on a... on the plot plan the use of immediate adjacent properties such as, residential area, pasture, box...

  20. Alternatives to the EEG levy. Possible effects of a reform of the energy transition financing on the industry

    International Nuclear Information System (INIS)

    Scheyhing, Joerg

    2017-01-01

    Although it has been adjusted six times since the year 2000, it has not yet been possible to manage the unrestricted growth of the EEG levy. In the 2017 election year, it becomes therefore ever more obvious that an alternative way to finance the energy transition is high on the political agenda. This would lead to significant changes for energy-intensive companies, regardless of whether they have benefited from a release from the levy or not. At the same time, the alternatives currently discussed have quite different effects on the industrial companies concerned and thereby the industry location Germany. [de

  1. 46 CFR 108.133 - Hull superstructure, structural bulkheads, decks, and deckhouses.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Hull superstructure, structural bulkheads, decks, and deckhouses. 108.133 Section 108.133 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A... Protection § 108.133 Hull superstructure, structural bulkheads, decks, and deckhouses. Each hull...

  2. 13 CFR 108.1840 - Computation of NMVC Company's Capital Impairment Percentage.

    Science.gov (United States)

    2010-01-01

    ... Capital Impairment Percentage. 108.1840 Section 108.1840 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL (âNMVCâ) PROGRAM NMVC Company's Noncompliance With Terms of Leverage Computation of Nmvc Company's Capital Impairment § 108.1840 Computation of NMVC Company's Capital Impairment...

  3. 7 CFR 900.106 - Assignment of mediator.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Assignment of mediator. 900.106 Section 900.106 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Assignment of mediator. The Director of the Division shall assign a mediator, from the group designated by...

  4. Possible alternatives for diesel powered mobile equipment for the conditions of deep mines

    Energy Technology Data Exchange (ETDEWEB)

    Paraszczak, J.; Kotersi, O [Laval Univ., Quebec City, PQ (Canada). Dept. of Mining, Metallurgical and Materials Engineering

    2008-07-01

    The challenges associated with mining at considerable depths were discussed. Mines such as Kidd Creek, LaRonde and Creighton are deeper than 2500 m. High rock temperature is among the challenges that operators face in such conditions. Conventional diesel powered load-hauling equipment constitute an additional source of heat and noxious gases. As such, more intense ventilation is needed in order to keep ambient temperature and air quality at a level that is acceptable for human workers. This paper examined possible alternatives for diesel powered equipment, including those that are commercially available as well as those that are underdevelopment or in the prototype stage. The equipment was reviewed with reference to the required infrastructure, stage of technology development and progress. The flexibility, practicality and economic viability of the equipment was also investigated. The potential for its use in deep Canadian mines was discussed along with the most promising drive alternatives for vehicles designed for deep mine operations. Electric drives have proven to be effective in many mining applications since they have significant advantages over diesel drives. The characteristics of cable powered equipment, trolley-wire powered equipment, and battery powered equipment were described. The key advantages and disadvantages of hybrid diesel electric equipment were also reviewed along with the viability of power plants based on the use of hydrogen. The principle types of hydrogen power plants include hydrogen combustion engines; HY-Drive systems and fuel cells. It was concluded that although there is no viable alternative for diesel engines at present, Canadian mining companies operating at great depths have made significant progress in these fields and remain among the leaders in mining innovation. 17 refs.

  5. 13 CFR 108.585 - Voluntary decrease in NMVC Company's Regulatory Capital.

    Science.gov (United States)

    2010-01-01

    ...'s Regulatory Capital. 108.585 Section 108.585 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL (âNMVCâ) PROGRAM Managing the Operations of a NMVC Company Voluntary Decrease in Regulatory Capital § 108.585 Voluntary decrease in NMVC Company's Regulatory Capital. You must...

  6. 40 CFR 90.106 - Certificate of conformity.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Certificate of conformity. 90.106... Standards and Certification Provisions § 90.106 Certificate of conformity. (a)(1) Except as provided in § 90... certificate of conformity covering such engines; however, engines manufactured during an annual production...

  7. 40 CFR 91.106 - Certificate of conformity.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Certificate of conformity. 91.106... Provisions § 91.106 Certificate of conformity. (a) Every manufacturer of a new marine SI engine produced... obtain a certificate of conformity covering each engine family. The certificate of conformity must be...

  8. Experience Of Using Metal-and-Concrete Cask TUK-108/1 For Storage And Transportation Of Spent Nuclear Fuel Of Decommissioned NPS

    Energy Technology Data Exchange (ETDEWEB)

    Barnes, E.; Dyer, R. [Environmental Protection Agency, Ronald Reagan Bldg. 3rd Floor 1200 Pennsylvania Av., NW Washington, D.C. 20024 (United States); Snipes, R. [Oak Ridge National Laboratories, VA (United States); Dolbenkov, V.G.; Guskov, V.D.; Korotkov, G.V. [Joint Stock Company ' KBSM' , 64 Lesnoy Av., St.Petersburg 194100 (Russian Federation); Makarchuk, T.F. [Joint Stock Company ' Atomstroyexport' , Potapovskiy str. 5, bld. 4, Moscow, 101990 (Russian Federation); Zakharchev, A.A. [State Corporation ' Rosatom' , 24-26 Ordinka St., Moscow, 100000 (Russian Federation)

    2009-06-15

    In past 10 years in Russia an intensive development of a new technology of management of spent nuclear fuel (SNF) has taken place. This technology is based on the concept of using a shielded cask which provides safety of its content (SNF) and meeting all other safety requirements to storage and transportation of SNF. Radiation protection against emission and non-propagation of activity outside the cask is ensured by the physical barriers such as all-metal or composite body, face work, inner structures to accommodate spent fuel assemblies (SFA), lids with sealing systems. Residual heat buildup is off-taken to the environment by natural way: emission and convection of surrounding air. The necessity in development of the cask technology of SNF management was conditioned by the situation at hand with defueling of Russian decommissioned nuclear-powered submarines (NPS) as the existed transport infrastructure and enterprises involved in fuel processing could not meet the demand for transportation and processing of SNF neither from reactors of all dismantled NPS, nor from reactors of NPS waiting for decommissioning. The US and Norway actively participated in the trilateral joint project with the Russian Federation aimed at creation of a cask prototype for interim storage and transportation of SNF of dismantled NPS. The 1.1 Project is a part of the Arctic Military Environmental Cooperation (AMEC) Program. In December 2000 the project was successfully completed by issuance of the certificate-permit for design and transportation of NP Submarine SNF. It was a first certified dual-purpose TUK from the MMC family. In these years 106 TUK-108/1 casks have been manufactured and supplied to PO Mayak, JSC CS Zvezda, JSC CS Zvezdochka and FSUE DalRAO. The storage pads for interim storage of TUK-108/1 have been built and currently are in operation on sites of SNF unloading from submarine reactors and SNF cask-loading such as JSC CS Zvezda, JSC CS Zvezdochka and FSUE DalRAO. In

  9. 13 CFR 108.1900 - Termination of participation as a NMVC Company.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Termination of participation as a NMVC Company. 108.1900 Section 108.1900 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL (âNMVCâ) PROGRAM Ending Operations as a NMVC Company § 108.1900...

  10. Site investigation SFR. Boremap mapping of core drilled borehole KFR106

    Energy Technology Data Exchange (ETDEWEB)

    Winell, Sofia (Geosigma AB (Sweden))

    2010-06-15

    This report presents the result from the Boremap mapping of the core drilled borehole KFR106, drilled from an islet ca 220 m southeast of the pier above SFR. The borehole has a length of 300.13 m, and a bearing and inclination of 195.1 deg and -69.9 deg, respectively. The purpose of the location and orientation of the borehole is to investigate the possible occurrence of gently dipping, water-bearing structures in the area. The geological mapping is based on simultaneous study of drill core and borehole image (BIPS). The two lowermost meters of the drill core was mapped in Boremap without access to complementary BIPS-image. The dominating rock type, which occupies 72% of KFR106, is fine- to medium-grained, metagranite granodiorite (rock code 101057), which is foliated with a medium to strong intensity. Pegmatite to pegmatitic granite (rock code 101061) is the second most common rock type and it occupies 16% of the mapped interval. It is also frequent as smaller rock occurrences (< 1 m) in other rock types throughout the borehole. Subordinate rock types are fine- to medium-grained granite (rock code 111058), felsic to intermediate meta volcanic rock (rock code 103076), fine- to medium-grained metagranitoid (rock code 101051) and amphibolite (rock code 102017). Totally 49% of the rock in KFR106 has been mapped as altered, where muscovitization and oxidation is the two most common. Additional shorter intervals of alterations are in decreasing order of abundance quartz dissolution, epidotization, argillization, albitization, chloritization, laumontization and carbonatization. A total number of 2801 fractures are registered in KFR106. Of these are 1059 open, 1742 sealed and 84 partly open. This result in the following fracture frequencies: 6.0 sealed fractures/m, 3.7 open fractures/m and 0.3 partly open fractures/m. In addition there are 5 narrow brecciated zones, and 20 sealed networks with a total length of 18 m. The most frequent fracture fillings in KFR106 are

  11. 41 CFR 101-25.106 - Servicing of office machines.

    Science.gov (United States)

    2010-07-01

    ... machines. 101-25.106 Section 101-25.106 Public Contracts and Property Management Federal Property...-General Policies § 101-25.106 Servicing of office machines. (a) The determination as to whether office machines are to be serviced by use of annual maintenance contracts or per-call arrangements shall be made...

  12. 9 CFR 113.106 - Clostridium Chauvoei Bacterin.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Clostridium Chauvoei Bacterin. 113.106 Section 113.106 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF... Animal and Plant Health Inspection Service, shall be used for challenge 14 to 15 days following the last...

  13. Analysis of Elektrogorsk 108 test facility experimental data

    International Nuclear Information System (INIS)

    Urbonas, R.

    2001-01-01

    In the paper an evaluation of experimental data obtained at Russian Elektrogorsk 108 (E-108) test facility is presented. E-108 facility is a scaled model of Russian RBMK design reactor. An attempt to validate state-of-the-art thermal hydraulic codes on the basis of E-108 test facility was made. Originally these codes were developed and validated for BWRs and PWRs. Since state-of-art thermal hydraulic codes are widely used for simulation of RBMK reactors further codes' implementation and validation is required. The facility was modelled by employing RELAP5 (INEEL, USA) thermal hydraulic system analysis best estimate code. The results show dependence from number of nodes used in the heated channels, frictional and form losses employed. The obtained oscillatory behaviour is resulted by density wave and critical heat flux. It is shown that codes are able to predict thermal hydraulic instability and sudden heat structure temperature excursion, when critical heat flux is approached, well. In addition, an uncertainty analysis of one of the experiments was performed by employing GRS developed System for Uncertainty and Sensitivity Analysis (SUSA). It was one of the first attempts to use this statistic-based methodology in Lithuania.(author)

  14. 13 CFR 108.320 - Contents of comprehensive business plan.

    Science.gov (United States)

    2010-01-01

    ... plan. 108.320 Section 108.320 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS... Contents of comprehensive business plan. (a) Executive summary. The executive summary must include a... or entity, or any other firm or entity essential to the success of the Applicant's business plan. [66...

  15. 9 CFR 354.106 - Travel expenses and other charges.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Travel expenses and other charges. 354.106 Section 354.106 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF... § 354.106 Travel expenses and other charges. Charges are to be made to cover the cost of travel and...

  16. 13 CFR 108.690 - Examinations.

    Science.gov (United States)

    2010-01-01

    ....690 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL (âNMVCâ) PROGRAM Recordkeeping, Reporting, and Examination Requirements for NMVC Companies Examinations of Nmvc Companies by Sba for Regulatory Compliance § 108.690 Examinations. All NMVC companies must submit to annual...

  17. 46 CFR 108.413 - Fusible element fire detection system.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Fusible element fire detection system. 108.413 Section... UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.413 Fusible element fire detection system. (a) A fusible element fire detection system may be installed. (b) The arrangements for the system...

  18. 46 CFR 108.525 - Survival craft number and arrangement.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft number and arrangement. 108.525 Section... UNITS DESIGN AND EQUIPMENT Lifesaving Equipment § 108.525 Survival craft number and arrangement. (a... arrangement of survival craft: (1) Lifeboats with an aggregate capacity to accommodate the total number of...

  19. Diuron in water: functional toxicity and intracellular detoxification patterns of active concentrations assayed in tandem by a yeast-based probe.

    Science.gov (United States)

    Dragone, Roberto; Cheng, Rachel; Grasso, Gerardo; Frazzoli, Chiara

    2015-04-01

    A study on the acute and chronic effects of the herbicide diuron was carried out. The test, basing on a yeast cell probe, investigated the interference with cellular catabolism and possible self-detoxification capacity of Saccharomyces cerevisiae. Aerobic respiration was taken as the toxicological end-point. Percentage interference (%r) with cellular respiration was measured in water by increased dissolved O2 concentration (ppm) after exposure to different doses. Interference was calculated through the comparison of respiratory activity of exposed and non-exposed cells. Short-term and long-term (6 and 24 h respectively) exposures were also considered. The test for short-term exposure gave positive %r values except that for 10-6 M (11.11%, 11.76%, 13.33% and 0% for 10-10 M, 10-8 M, 10-7 M and 10-6 M respectively). In the case of long-term exposure the test showed positive %r values, but less effect than short-term exposure until 10-8 M and much higher at 10-6 M (7.41%, 8.82%, 11.76% and 6.06% for 10-10 M, 10-8 M, 10-7 M and 10-6 M respectively). The findings of aerobic respiration as toxicological end-point were in agreement with known mechanisms of toxicity and intracellular detoxification for both the doses and exposure times employed.

  20. Ballistic V50 Evaluation of TIMET Ti108

    Science.gov (United States)

    2018-02-01

    threat by 1 m/s. Future studies or adjustments to the chemistry of the Ti108 can be conducted to optimize ballistic performance. 15. SUBJECT TERMS...10 Fig. A-2 30-mm APDS overall back of plate .................................................... 10 List of Tables Table 1 Chemistry of Ti108...performance of different titanium alloys. Conventional Ti-6Al-4V is commonly used in aerospace frames and engine components, but has difficulty passing

  1. The Versatile Extended Thoracodorsal Artery Perforator Flap for Breast Reconstruction

    DEFF Research Database (Denmark)

    Jacobs, Jordan; Børsen-Koch, Mikkel; Gunnarsson, Gudjon L.

    2016-01-01

    complications occurred in 10 of 106 (10%) cases and included hematoma (1/108), venous congestion (2/108), and partial flap necrosis (7/108). The reconstructive goal was achieved in 103 of 106 (97%) flaps. CONCLUSIONS: The TAP flap is a pedicled, fasciocutaneous flap that can be used for total breast...

  2. 7 CFR 1221.108 - Procedure.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... INFORMATION ORDER Sorghum Promotion, Research, and Information Order Sorghum Promotion, Research, and Information Board § 1221.108 Procedure. (a) At a Board meeting, it will be considered a quorum when a simple...

  3. Energy deposition by a {sup 106}Ru/{sup 106}Rh eye applicator simulated using LEPTS, a low-energy particle track simulation

    Energy Technology Data Exchange (ETDEWEB)

    Fuss, M.C. [Instituto de Fisica Fundamental, Consejo Superior de Investigaciones Cientificas (CSIC), Serrano 113-bis, 28006 Madrid (Spain); Munoz, A.; Oller, J.C. [Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas (CIEMAT), Avenida Complutense 22, 28040 Madrid (Spain); Blanco, F. [Departamento de Fisica Atomica, Molecular y Nuclear, Universidad Complutense de Madrid, Avenida Complutense, 28040 Madrid (Spain); Williart, A. [Departamento de Fisica de los Materiales, Universidad Nacional de Educacion a Distancia, Senda del Rey 9, 28040 Madrid (Spain); Limao-Vieira, P. [Laboratorio de Colisoes Atomicas e Moleculares, Departamento de Fisica, CEFITEC, FCT-Universidade Nova de Lisboa, Quinta da Torre, 2829-516 Caparica (Portugal); Borge, M.J.G.; Tengblad, O. [Instituto de Estructura de la Materia, Consejo Superior de Investigaciones Cientificas (CSIC), Serrano 113-bis, 28006 Madrid (Spain); Huerga, C.; Tellez, M. [Hospital Universitario La Paz, Paseo de la Castellana 261, 28046 Madrid (Spain); Garcia, G., E-mail: g.garcia@iff.csic.es [Instituto de Fisica Fundamental, Consejo Superior de Investigaciones Cientificas (CSIC), Serrano 113-bis, 28006 Madrid (Spain); Departamento de Fisica de los Materiales, Universidad Nacional de Educacion a Distancia, Senda del Rey 9, 28040 Madrid (Spain)

    2011-09-15

    The present study introduces LEPTS, an event-by-event Monte Carlo programme, for simulating an ophthalmic {sup 106}Ru/{sup 106}Rh applicator relevant in brachytherapy of ocular tumours. The distinctive characteristics of this code are the underlying radiation-matter interaction models that distinguish elastic and several kinds of inelastic collisions, as well as the use of mostly experimental input data. Special emphasis is placed on the treatment of low-energy electrons for generally being responsible for the deposition of a large portion of the total energy imparted to matter. - Highlights: > We present the Monte Carlo code LEPTS, a low-energy particle track simulation. > Carefully selected input data from 10 keV to 1 eV. > Application to an electron emitting Ru-106/Rh-106 plaque used in brachytherapy.

  4. 7 CFR 3565.108 - Responsibility for actions of agents and mortgage brokers.

    Science.gov (United States)

    2010-01-01

    ... brokers. 3565.108 Section 3565.108 Agriculture Regulations of the Department of Agriculture (Continued... Requirements § 3565.108 Responsibility for actions of agents and mortgage brokers. An approved lender is responsible for the actions of its agents and mortgage brokers. ...

  5. 26 CFR 1.108-3 - Intercompany losses and deductions.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Intercompany losses and deductions. 1.108-3... Intercompany losses and deductions. (a) General rule. This section applies to certain losses and deductions... attributes to which section 108(b) applies, a loss or deduction not yet taken into account under section 267...

  6. 47 CFR 68.106 - Notification to provider of wireline telecommunications.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Notification to provider of wireline telecommunications. 68.106 Section 68.106 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON... of Terminal Equipment § 68.106 Notification to provider of wireline telecommunications. (a) General...

  7. Star Formation Conditions in a Planck Galactic Cold Clump, G108.84–00.81

    Science.gov (United States)

    Kim, Jungha; Lee, Jeong-Eun; Liu, Tie; Kim, Kee-Tae; Wu, Yuefang; Tatematsu, Ken‧ichi; Liu, Sheng-Yuan; JCMT Large Program “SCOPE” Collaboration; TRAO Key Science Program “TOP” Collaboration

    2017-07-01

    We present the results from a series of ground-based radio observations toward a Planck Galactic Cold Clump (PGCC), PGCC G108.84–00.81, which is located in one curved filamentary cloud in the vicinity of an extended H II region Sh2-152 and SNR G109.1-1.0. PGCC G108.84–00.81 is mainly composed of two clumps, “G108–N” and “G108–S”. In the 850 μm dust continuum emission map, G108–N is shown as one component while G108–S is fragmented into four components. There is no infrared source associated with G108–N, while there are two infrared sources (IRS 1 and IRS 2) associated with G108–S. The total mass of G108–N is larger than the Jeans mass, suggesting that G108–N is gravitationally unstable and a potential place for a future star formation. The clump properties of G108–N and G108–S such as the gas temperature and the column density, are not distinctly different. However, G108–S is slightly more evolved than G108–N, if considering the CO depletion factor, molecular abundances, and association with infrared sources. G108–S seems to be affected by the compression from Sh2-152, while G108–N is relatively protected from the external effect.

  8. Star Formation Conditions in a Planck Galactic Cold Clump, G108.84–00.81

    International Nuclear Information System (INIS)

    Kim, Jungha; Lee, Jeong-Eun; Liu, Tie; Kim, Kee-Tae; Wu, Yuefang; Tatematsu, Ken'ichi; Liu, Sheng-Yuan

    2017-01-01

    We present the results from a series of ground-based radio observations toward a Planck Galactic Cold Clump (PGCC), PGCC G108.84–00.81, which is located in one curved filamentary cloud in the vicinity of an extended H ii region Sh2-152 and SNR G109.1-1.0. PGCC G108.84–00.81 is mainly composed of two clumps, “G108–N” and “G108–S”. In the 850 μ m dust continuum emission map, G108–N is shown as one component while G108–S is fragmented into four components. There is no infrared source associated with G108–N, while there are two infrared sources (IRS 1 and IRS 2) associated with G108–S. The total mass of G108–N is larger than the Jeans mass, suggesting that G108–N is gravitationally unstable and a potential place for a future star formation. The clump properties of G108–N and G108–S such as the gas temperature and the column density, are not distinctly different. However, G108–S is slightly more evolved than G108–N, if considering the CO depletion factor, molecular abundances, and association with infrared sources. G108–S seems to be affected by the compression from Sh2-152, while G108–N is relatively protected from the external effect.

  9. Star Formation Conditions in a Planck Galactic Cold Clump, G108.84–00.81

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jungha; Lee, Jeong-Eun [School of Space Research, Kyung Hee University, 1732, Deogyeong-daero, Giheung-gu, Yongin-si, Gyeonggi-do (Korea, Republic of); Liu, Tie; Kim, Kee-Tae [Korea Astronomy and Space Science Institute, 776 Daedeokdaero, Yuseong, Daejeon 34055 (Korea, Republic of); Wu, Yuefang [Department of Astronomy, Peking University, 100871, Beijing (China); Tatematsu, Ken' ichi [Department of Astronomical Science, SOKENDAI - The Graduate University for Advanced Studies, National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan); Liu, Sheng-Yuan, E-mail: jeongeun.lee@khu.ac.kr [Academia Sinica, Institute of Astronomy and Astrophysics, P.O. Box 23-141, Taipei 106, Taiwan (China); Collaboration: JCMT Large Program “SCOPE” Collaboration, and TRAO Key Science Program “TOP” Collaboration

    2017-07-01

    We present the results from a series of ground-based radio observations toward a Planck Galactic Cold Clump (PGCC), PGCC G108.84–00.81, which is located in one curved filamentary cloud in the vicinity of an extended H ii region Sh2-152 and SNR G109.1-1.0. PGCC G108.84–00.81 is mainly composed of two clumps, “G108–N” and “G108–S”. In the 850 μ m dust continuum emission map, G108–N is shown as one component while G108–S is fragmented into four components. There is no infrared source associated with G108–N, while there are two infrared sources (IRS 1 and IRS 2) associated with G108–S. The total mass of G108–N is larger than the Jeans mass, suggesting that G108–N is gravitationally unstable and a potential place for a future star formation. The clump properties of G108–N and G108–S such as the gas temperature and the column density, are not distinctly different. However, G108–S is slightly more evolved than G108–N, if considering the CO depletion factor, molecular abundances, and association with infrared sources. G108–S seems to be affected by the compression from Sh2-152, while G108–N is relatively protected from the external effect.

  10. 14 CFR 1221.108 - Establishment of the NASA Unified Visual Communications System.

    Science.gov (United States)

    2010-01-01

    ... Visual Communications System. The NASA Graphics Coordinator will develop and issue changes and additions... Communications System. 1221.108 Section 1221.108 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE... Communications System § 1221.108 Establishment of the NASA Unified Visual Communications System. (a) The NASA...

  11. 23 CFR 500.108 - SMS.

    Science.gov (United States)

    2010-04-01

    ... SYSTEMS Management Systems § 500.108 SMS. An SMS is a systematic process with the goal of reducing the... Management Systems: Good Practices for Development and Implementation.” 3 An effective SMS should include, at a minimum: 3 Safety Management Systems: Good Practices for Development and Implementation, FHWA and...

  12. 13 CFR 108.510 - SBA approval of NMVC Company's Investment Adviser/Manager.

    Science.gov (United States)

    2010-01-01

    ... Investment Adviser/Manager. 108.510 Section 108.510 Business Credit and Assistance SMALL BUSINESS... and Compensation § 108.510 SBA approval of NMVC Company's Investment Adviser/Manager. You may employ an Investment Adviser/Manager who will be subject to the supervision of your board of directors...

  13. Replacement of Ser108 in Plasmodium falciparum enolase results in weak Mg(II) binding: role of a parasite-specific pentapeptide insert in stabilizing the active conformation of the enzyme.

    Science.gov (United States)

    Dutta, Sneha; Mukherjee, Debanjan; Jarori, Gotam K

    2015-06-01

    A distinct structural feature of Plasmodium falciparum enolase (Pfeno) is the presence of a five amino acid insert -104EWGWS108- that is not found in host enolases. Its conservation among apicomplexan enolases has raised the possibility of its involvement in some important physiological function(s). Deletion of this sequence is known to lower k(cat)/K(m), increase K(a) for Mg(II) and convert dimer into monomers (Vora HK, Shaik FR, Pal-Bhowmick I, Mout R & Jarori GK (2009) Arch Biochem Biophys 485, 128-138). These authors also raised the possibility of the formation of an H-bond between Ser108 and Leu49 that could stabilize the apo-Pfeno in an active closed conformation that has high affinity for Mg(II). Here, we examined the effect of replacement of Ser108 with Gly/Ala/Thr on enzyme activity, Mg(II) binding affinity, conformational states and oligomeric structure and compared it with native recombinant Pfeno. The results obtained support the view that Ser108 is likely to be involved in the formation of certain crucial H-bonds with Leu49. The presence of these interactions can stabilize apo-Pfeno in an active closed conformation similar to that of Mg(II) bound yeast enolase. As predicted, S108G/A-Pfeno variants (where Ser108-Leu49 H-bonds are likely to be disrupted) were found to exist in an open conformation and had low affinity for Mg(II). They also required Mg(II) induced conformational changes to acquire the active closed conformational state essential for catalysis. The possible physiological relevance of apo-Pfeno being in such an active state is discussed. © 2015 FEBS.

  14. 41 CFR 115-1.106 - Applicability of FPMR.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Applicability of FPMR. 115-1.106 Section 115-1.106 Public Contracts and Property Management Federal Property Management Regulations System (Continued) ENVIRONMENTAL PROTECTION AGENCY 1-INTRODUCTION 1.1-Regulation System § 115-1...

  15. 41 CFR 101-1.106 - Applicability of FPMR.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Applicability of FPMR. 101-1.106 Section 101-1.106 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 1-INTRODUCTION 1.1-Regulation System § 101...

  16. 5 CFR 9901.106 - Relationship to other provisions.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Relationship to other provisions. 9901.106 Section 9901.106 Administrative Personnel DEPARTMENT OF DEFENSE HUMAN RESOURCES MANAGEMENT AND....S.C. 5545b; and (iii) Recruitment, relocation, and retention payments under 5 U.S.C. 5753 through...

  17. 29 CFR 1952.106 - Where the plan may be inspected.

    Science.gov (United States)

    2010-07-01

    ... and copied during normal business hours at the following locations: Office of State Programs... 29 Labor 9 2010-07-01 2010-07-01 false Where the plan may be inspected. 1952.106 Section 1952.106..., DEPARTMENT OF LABOR (CONTINUED) APPROVED STATE PLANS FOR ENFORCEMENT OF STATE STANDARDS Oregon § 1952.106...

  18. The Codacs™ direct acoustic cochlear implant actuator: exploring alternative stimulation sites and their stimulation efficiency.

    Science.gov (United States)

    Grossöhmichen, Martin; Salcher, Rolf; Kreipe, Hans-Heinrich; Lenarz, Thomas; Maier, Hannes

    2015-01-01

    This work assesses the efficiency of the Codacs system actuator (Cochlear Ltd., Sydney Australia) in different inner ear stimulation modalities. Originally the actuator was intended for direct perilymph stimulation after stapedotomy using a piston prosthesis. A possible alternative application is the stimulation of middle ear structures or the round window (RW). Here the perilymph stimulation with a K-piston through a stapes footplate (SFP) fenestration (N = 10) as well as stimulation of the stapes head (SH) with a Bell prosthesis (N = 9), SFP stimulation with an Omega/Aerial prosthesis (N = 8) and reverse RW stimulation (N = 10) were performed in cadaveric human temporal bones (TBs). Codacs actuator output is expressed as equivalent sound pressure level (eq. SPL) using RW and SFP displacement responses, measured by Laser Doppler velocimetry as reference. The axial actuator coupling force in stimulation of stapes and RW was adjusted to ~5 mN. The Bell prosthesis and Omega/Aerial prosthesis stimulation generated similar mean eq. SPLs (Bell: 127.5-141.8 eq. dB SPL; Omega/Aerial: 123.6-143.9 eq. dB SPL), being significantly more efficient than K-piston perilymph stimulation (108.6-131.6 eq. dB SPL) and RW stimulation (108.3-128.2 eq. dB SPL). Our results demonstrate that SH, SFP and RW are adequate alternative stimulation sites for the Codacs actuator using coupling prostheses and an axial coupling force of ~5 mN. Based on the eq. SPLs, all investigated methods were adequate for in vivo hearing aid applications, provided that experimental conditions including constant coupling force will be implemented.

  19. Acetylcholinesterase triggers the aggregation of PrP 106-126

    International Nuclear Information System (INIS)

    Pera, M.; Roman, S.; Ratia, M.; Camps, P.; Munoz-Torrero, D.; Colombo, L.; Manzoni, C.; Salmona, M.; Badia, A.; Clos, M.V.

    2006-01-01

    Acetylcholinesterase (AChE), a senile plaque component, promotes amyloid-β-protein (Aβ) fibril formation in vitro. The presence of prion protein (PrP) in Alzheimer's disease (AD) senile plaques prompted us to assess if AChE could trigger the PrP peptides aggregation as well. Consequently, the efficacy of AChE on the PrP peptide spanning-residues 106-126 aggregation containing a coumarin fluorescence probe (coumarin-PrP 106-126) was studied. Kinetics of coumarin-PrP 106-126 aggregation showed a significant increase of maximum size of aggregates (MSA), which was dependent on AChE concentration. AChE-PrP 106-126 aggregates showed the tinctorial and optical amyloid properties as determined by polarized light and electronic microscopy analysis. A remarkable inhibition of MSA was obtained with propidium iodide, suggesting that AChE triggers PrP 106-126 and Aβ aggregation through a similar mechanism. Huprines (AChE inhibitors) also significantly decreased MSA induced by AChE as well, unveiling the potential interest for some AChE inhibitors as a novel class of potential anti-prion drugs

  20. 20 CFR 653.106 - JS day-haul responsibilities.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false JS day-haul responsibilities. 653.106 Section... THE EMPLOYMENT SERVICE SYSTEM Services for Migrant and Seasonal Farmworkers (MSFWs) § 653.106 JS day... Regional Administrator is obtained. (b) No JS applicants shall be referred to non-JS operated day-haul...

  1. 34 CFR 300.106 - Extended school year services.

    Science.gov (United States)

    2010-07-01

    ... services means special education and related services that— (1) Are provided to a child with a disability... 34 Education 2 2010-07-01 2010-07-01 false Extended school year services. 300.106 Section 300.106 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION...

  2. Report on the IRSN's investigations following the widespread detection of 106Ru in Europe early October 2017

    International Nuclear Information System (INIS)

    2018-01-01

    Ruthenium-106 ( 106 Ru) is an anthropogenic radionuclide which is usually not observed in the atmosphere. Early October 2017, it was detected in almost all European countries. Observed activities ranged from a few μBq/m 3 to about 150 mBq/m 3 . Although, these concentrations did not pose any health or environmental issues, this widespread detection suggested that the source-term must have been quite high. Taken into account all these elements, IRSN decided to perform further investigations in order (1) to identify the possible location of the source, 2) to assess the total activity released and the release duration and 3) to understand the process that could be at the origin of the release of 106 Ru alone. The present report summarizes the main results of these investigations

  3. 34 CFR 106.42 - Textbooks and curricular material.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Textbooks and curricular material. 106.42 Section 106.42 Education Regulations of the Offices of the Department of Education OFFICE FOR CIVIL RIGHTS, DEPARTMENT OF EDUCATION NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on...

  4. 46 CFR 108.540 - Survival craft muster and embarkation arrangements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft muster and embarkation arrangements. 108... OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Lifesaving Equipment § 108.540 Survival craft muster and... craft muster station and embarkation station for a survival craft which is boarded before it is launched...

  5. 30 CFR 206.108 - Does MMS protect information I provide?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Does MMS protect information I provide? 206.108... MANAGEMENT PRODUCT VALUATION Federal Oil § 206.108 Does MMS protect information I provide? Certain information you submit to MMS regarding valuation of oil, including transportation allowances, may be exempt...

  6. 13 CFR 108.520 - Management Expenses of a NMVC Company.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Management Expenses of a NMVC Company. 108.520 Section 108.520 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL (âNMVCâ) PROGRAM Managing the Operations of a NMVC Company Management and Compensation...

  7. 5 CFR 3601.106 - Limitation on solicited sales.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Limitation on solicited sales. 3601.106... FOR EMPLOYEES OF THE DEPARTMENT OF DEFENSE § 3601.106 Limitation on solicited sales. A DoD employee shall not knowingly solicit or make solicited sales to DoD personnel who are junior in rank, grade or...

  8. 46 CFR 108.407 - Detectors for electric fire detection system.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Detectors for electric fire detection system. 108.407... DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems § 108.407 Detectors for electric fire detection system. (a) Each detector in an electric fire detection system must be located where— (1) No...

  9. Vapor space characterization of waste Tank 241-BY-108: Results from samples collected on 10/27/94

    International Nuclear Information System (INIS)

    McVeety, B.D.; Clauss, T.W.; Ligotke, M.W.

    1995-10-01

    This report describes inorganic and organic analyses results from samples obtained from the headspace of the Hanford waste storage Tank 241-BY-108 (referred to as Tank BY-108). The results described here were obtained to support safety and toxicological evaluations. A summary of the results for inorganic and organic analytes is listed in Table 1. Detailed descriptions of the results appear in the text. Quantitative results were obtained for the inorganic compounds ammonia (NH 3 ), nitrogen dioxide (NO 2 ), nitric oxide (NO), and water vapor (H 2 O). Trends in NH 3 and H 2 O samples indicated a possible sampling problem. Sampling for hydrogen cyanide (HCN) and sulfur oxides (SO x ) was not requested. In addition, the authors looked for the 40 TO-14 compounds plus an additional 15 analytes. Of these, 17 were observed above the 5-ppbv reporting cutoff. Also, eighty-one organic tentatively identified compounds (TICs) were observed above the reporting cutoff (ca.) 10 ppbv, and are reported with concentrations that are semiquantitative estimates based on internal standard response factors. The nine organic analytes with the highest estimated concentrations are listed in Summary Table 1 and account for approximately 48% of the total organic components in the headspace of Tank BY-108. Three permanent gases, hydrogen (H 2 ), carbon dioxide (CO 2 ), and nitrous oxide (N 2 O) were also detected. Tank BY-108 is on the Ferrocyanide Watch List

  10. 13 CFR 108.140 - SBA approval of initial Management Expenses.

    Science.gov (United States)

    2010-01-01

    ... VENTURE CAPITAL (âNMVCâ) PROGRAM Qualifications for the NMVC Program Organizing A Nmvc Company § 108.140 SBA approval of initial Management Expenses. A NMVC Company must have its Management Expenses approved by SBA at the time of designation as a NMVC Company. (See § 108.520 for the definition of Management...

  11. 13 CFR 108.380 - Final approval as a NMVC Company.

    Science.gov (United States)

    2010-01-01

    ... VENTURE CAPITAL (âNMVCâ) PROGRAM Evaluation and Selection of NMVC Companies § 108.380 Final approval as a... amount of Regulatory Capital set forth in its application, pursuant to § 108.310(a)(1); and (B) The... at least 30 percent of its Regulatory Capital if the Conditionally Approved NMVC Company— (i) Already...

  12. 40 CFR 81.106 - Greenville-Spartanburg Intrastate Air Quality Control Region.

    Science.gov (United States)

    2010-07-01

    ... Quality Control Region. 81.106 Section 81.106 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.106 Greenville-Spartanburg Intrastate Air Quality Control Region. The Greenville-Spartanburg Intrastate Air Quality Control Region (South Carolina) consists of the territorial...

  13. 48 CFR 49.108-3 - Settlement procedure.

    Science.gov (United States)

    2010-10-01

    ... MANAGEMENT TERMINATION OF CONTRACTS General Principles 49.108-3 Settlement procedure. (a) Contractors shall settle with subcontractors in general conformity with the policies and principles relating to settlement...

  14. Shortcomings of the industrial quality assurance of {sup 106}Ru ophthalmic plaques; Therapierelevante Schwachstellen bei der industriellen Qualitaetssicherung von {sup 106}Ru-Augenapplikatoren

    Energy Technology Data Exchange (ETDEWEB)

    Kaulich, T.W.; Nuesslin, F. [Universitaetsklinik fuer Radioonkologie, Tuebingen (Germany). Abt. Medizinische Physik; Zurheide, J. [BrainLAB AG, Heimstetten (Germany); Fluehs, D. [Abt. Strahlentherapie, Bereich klinische Strahlenphysik, Universitaetsklinikum Essen (Germany); Haug, T. [Isotopenlabor der Univ. Tuebingen (Germany); Bamberg, M. [Abt. Radioonkologie, Universitaetsklinik fuer Radioonkologie, Tuebingen (Germany)

    2001-11-01

    Background: Beta emitting {sup 106}Ru applicators manufactured by Bebig GmbH (Berlin, Germany) are widely used to treat intraocular tumors. The applicators are fixed to the bulbus and removed after several days. The following therapy relevant defects have been detected by an internal clinical acceptance test: risk of leakage and inconsistent dose-rate specifications by the manufacturer. In the meantime, components of the internal clinical acceptance test have been adopted successfully by the manufacturer of the {sup 106}Ru ophthalmic plaques. Material and Method: {sup 106}Ru ophthalmic plaques were tested with the following internal clinical acceptance tests: visual inspection, surface contamination, leakage, and dose-rate verification. The surface contamination test consists of a wet wipe test at moderate pressure. For the leakage test of the {sup 106}Ru ophthalmic plaques a clinically relevant scenario was developed in which the contact of the applicator with human tissue is simulated. In the course of it the applicator is inserted into Ringer's solution for several days. The certified energy dose-rate statements of the manufacturer are examined with a 1 mm{sup 3} plastic scintillator for consistency. (orig.) [German] Hintergrund: {sup 106}Ru-Augenapplikatoren der Fa. Bebig (Berlin) werden zur strahlentherapeutischen Behandlung von intraokularen Tumoren eingesetzt. Die Applikatoren werden sklerakontaktierend am Bulbus fixiert und nach mehreren Tagen wieder entfernt. Durch eine klinikinterne Eingangspruefung wurden folgende therapierelevante Maengel bei den Augenapplikatoren entdeckt: mangelhafte Dichtheit und inkonsistente Dosisleistungsangaben des Herstellers. Ein Teil dieser klinikinternen Eingangspruefung wurde inzwischen vom Hersteller der {sup 106}Ru-Augenapplikatoren uebernommen und erfolgreich eingesetzt. Material und Methode: Es wurden {sup 106}Ru-Augenapplikatoren durch folgende klinikinterne Eingangspruefungen getestet: optische Inspektion

  15. 41 CFR 105-64.108 - How does GSA safeguard personal information?

    Science.gov (United States)

    2010-07-01

    ... personal information? 105-64.108 Section 105-64.108 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION Regional Offices-General... GSA safeguard personal information? (a) System managers will establish administrative, technical, and...

  16. 7 CFR 1924.108 - Grading and drainage.

    Science.gov (United States)

    2010-01-01

    ... REGULATIONS CONSTRUCTION AND REPAIR Planning and Performing Site Development Work § 1924.108 Grading and... from buildings and foundations, minimize earth settlement and erosion, and assure that drainage from...

  17. 48 CFR 18.106 - Acquisitions from Federal Prison Industries, Inc. (FPI).

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Acquisitions from Federal Prison Industries, Inc. (FPI). 18.106 Section 18.106 Federal Acquisition Regulations System FEDERAL... Flexibilities 18.106 Acquisitions from Federal Prison Industries, Inc. (FPI). Purchase from FPI is not mandatory...

  18. 23 CFR 635.108 - Health and safety.

    Science.gov (United States)

    2010-04-01

    ... CONSTRUCTION AND MAINTENANCE Contract Procedures § 635.108 Health and safety. Contracts for projects shall... to protect property in connection with the performance of the work covered by the contract. ...

  19. 24 CFR 811.108 - Debt service reserve.

    Science.gov (United States)

    2010-04-01

    ... AND URBAN DEVELOPMENT (SECTION 8 HOUSING ASSISTANCE PROGRAMS, SECTION 202 DIRECT LOAN PROGRAM, SECTION... DISABILITIES PROGRAM) TAX EXEMPTION OF OBLIGATIONS OF PUBLIC HOUSING AGENCIES AND RELATED AMENDMENTS § 811.108...

  20. 7 CFR 1221.106 - Removal.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... INFORMATION ORDER Sorghum Promotion, Research, and Information Order Sorghum Promotion, Research, and Information Board § 1221.106 Removal. If the Secretary determines that any person appointed under this part...

  1. Uncertainties in the measured quantities of water leaving waste Tank 241-C-106 via the ventilation system

    Energy Technology Data Exchange (ETDEWEB)

    Minteer, D.J.

    1995-01-23

    The purpose of this analysis is to estimate the uncertainty in the measured quantity of water which typically leaves Tank 241-C-106 via the ventilation system each month. Such measurements are essential for heat removal estimation and tank liquid level verification purposes. The uncertainty associated with the current, infrequent, manual method of measurement (involves various psychrometric and pressure measurements) is suspected to be unreasonably high. Thus, the possible reduction of this uncertainty using a continuous, automated method of measurement will also be estimated. There are three major conclusions as a result of this analysis: (1) the uncertainties associated with the current (infrequent, manual) method of measuring the water which typically leaves Tank 241-C-106 per month via the ventilation system are indeed quite high (80% to 120%); (2) given the current psychrometric and pressure measurement methods and any tank which loses considerable moisture through active ventilation, such as Tank 241-C-106, significant quantities of liquid can actually leak from the tank before a leak can be positively identified via liquid level measurement; (3) using improved (continuous, automated) methods of taking the psychrometric and pressure measurements, the uncertainty in the measured quantity of water leaving Tank 241-C-106 via the ventilation system can be reduced by approximately an order of magnitude.

  2. Uncertainties in the measured quantities of water leaving waste Tank 241-C-106 via the ventilation system

    International Nuclear Information System (INIS)

    Minteer, D.J.

    1995-01-01

    The purpose of this analysis is to estimate the uncertainty in the measured quantity of water which typically leaves Tank 241-C-106 via the ventilation system each month. Such measurements are essential for heat removal estimation and tank liquid level verification purposes. The uncertainty associated with the current, infrequent, manual method of measurement (involves various psychrometric and pressure measurements) is suspected to be unreasonably high. Thus, the possible reduction of this uncertainty using a continuous, automated method of measurement will also be estimated. There are three major conclusions as a result of this analysis: (1) the uncertainties associated with the current (infrequent, manual) method of measuring the water which typically leaves Tank 241-C-106 per month via the ventilation system are indeed quite high (80% to 120%); (2) given the current psychrometric and pressure measurement methods and any tank which loses considerable moisture through active ventilation, such as Tank 241-C-106, significant quantities of liquid can actually leak from the tank before a leak can be positively identified via liquid level measurement; (3) using improved (continuous, automated) methods of taking the psychrometric and pressure measurements, the uncertainty in the measured quantity of water leaving Tank 241-C-106 via the ventilation system can be reduced by approximately an order of magnitude

  3. Inter-taxa differences in root uptake of 103/106Ru by plants

    International Nuclear Information System (INIS)

    Willey, N.J.; Fawcett, K.

    2006-01-01

    Ruthenium-106 is of potential radioecological importance but soil-to-plant Transfer Factors for it are available only for few plant species. A Residual Maximum Likelihood (REML) procedure was used to construct a database of relative 103/106 Ru concentrations in 114 species of flowering plants including 106 species from experiments and 12 species from the literature (with 4 species in both). An Analysis of Variance (ANOVA), coded using a recent phylogeny for flowering plants, was used to identify a significant phylogenetic effect on relative mean 103/106 Ru concentrations in flowering plants. There were differences of 2465-fold in the concentration to which plant species took up 103/106 Ru. Thirty-nine percent of the variance in inter-species differences could be ascribed to the taxonomic level of Order or above. Plants in the Orders Geraniales and Asterales had notably high uptake of 103/106 Ru compared to other plant groups. Plants on the Commelinoid monocot clades, and especially the Poaceae, had notably low uptake of 103/106 Ru. These data demonstrate that plant species are not independent units for 103/106 Ru concentrations but are linked through phylogeny. It is concluded that models of soil-to-plant transfer of 103/106 Ru should assume that; neither soil variables alone affect transfer nor plant species are independent units, and taking account of plant phylogeny might aid predictions of soil-to-plant transfer of 103/106 Ru, especially for species for which Transfer Factors are not available

  4. 41 CFR 115-1.108 - Agency implementation and supplementation of FPMR.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Agency implementation and supplementation of FPMR. 115-1.108 Section 115-1.108 Public Contracts and Property Management Federal Property Management Regulations System (Continued) ENVIRONMENTAL PROTECTION AGENCY 1-INTRODUCTION...

  5. 13 CFR 108.110 - Qualified management.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Qualified management. 108.110... management. An Applicant must show, to the satisfaction of SBA, that its current or proposed management team... or proposed management team has sufficient qualifications, SBA will consider information provided by...

  6. Electron paramagnetic resonance radiation dosimetry: possible inorganic alternatives to the EPR/alanine dosimeter

    International Nuclear Information System (INIS)

    Keizer, P.N.; Morton, J.R.; Preston, K.F.

    1991-01-01

    The intensity of the EPR spectrum of γ-irradiated L-α-alanine has been accepted by the International Atomic Energy Agency as a secondary standard for high-dose (10-100 000 Gy) dosimetry. The alanine dosimeter is not without its disadvantages, however, and in this article alternative EPR dosimeters are explored. These include SO 3 - in irradiated K 2 CH 2 (SO 3 ) 2 and CO 2 - in irradiated sodium formate (NaHCO 2 ), both of which have some advantages over CH 3 CHCO 2 - in L-α-alanine. Using as a readout parameter the peak-to-peak excursion of the strongest line, these systems have a four-fold sensitivity advantage over alanine. The radicals SO 3 - and CO 2 - are, moreover, found in a wide variety of matrices, and it may be possible to find one in which they are even stronger. The need to discover a dosimeter material sensitive enough to function in the 'clinical' dose range (below 10 Gy) is emphasized. (author)

  7. Studies towards the synthesis of radiolabeled R106-1(LY295337)

    International Nuclear Information System (INIS)

    Rodriguez, M.J.; Zweifel, M.J.

    1996-01-01

    A unique semisynthetic pathway has been used as a route to acquire radiolabeled material of a complex natural product, R106. The retro-aldol reaction of R106-1 gave a key intermediate R106-sarcosine that was used in a subsequent aldol reaction to incorporate acetone--[2- 14 C]. (author)

  8. 23 CFR 500.106 - PMS.

    Science.gov (United States)

    2010-04-01

    ... the “AASHTO Guidelines for Pavement Management Systems.” 1 1 AASHTO Guidelines for Pavement Management... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRANSPORTATION INFRASTRUCTURE MANAGEMENT MANAGEMENT AND MONITORING SYSTEMS Management Systems § 500.106 PMS. An effective PMS for Federal-aid highways is a systematic...

  9. Decay properties of nuclei close to Z = 108 and N = 162

    International Nuclear Information System (INIS)

    Dvorak, Jan

    2007-01-01

    The goal of the research conducted in the frame of this thesis was to investigate the decay properties of the nuclides 269-271 Hs and their daughters using an improved chemical separation and detection system. Shell stabilization was predicted in the region around Z=108 and N=162 in calculations, taking into account possible higher orders of deformations of the nuclei. The nucleus 270 Hs with a closed proton and a closed neutron deformed shell, was predicted to be ''deformed doubly magic''. Nuclei around 270 Hs can be produced only via fusion reactions at picobarn levels, resulting in a production rates of few atoms per day. Investigating short-lived nuclei using rapid chemical separation and subsequent on-line detection methods provides an independent and alternative means to electromagnetic on-line separators. Chemical separation of Hs in the form of HsO 4 provides an excellent tool to study the formation reactions and nuclear structure in this region of the chart of nuclides due to a high overall efficiency and a very high purification factor. The goal was accomplished, as element 108, hassium, was produced in the reaction 248 Cm( 26 Mg,xn) 274-x Hs and chemically isolated. After gas phase separation of HsO 4 , 26 genetically linked decay chains have been observed. These were attributed to decays of three different Hs isotopes produced in the 3-5n evaporation channels. The known decay chain of 269 Hs, the 5n evaporation product, serves as an anchor point, thus allowing the unambiguous assignment of the observed decay chains to the 5n, 4n, and 3n channels, respectively. Decay properties of five nuclei have been unambiguously established for the first time, including the one for the the doubly-magic nuclide 270 Hs. This hassium isotope is the next doubly magic nucleus after the well known 208 Pb and the first experimentally observed even-even nucleus on the predicted N=162 neutron shell. The observed decay properties provide strong indications for enhanced nuclear

  10. The Codacs™ direct acoustic cochlear implant actuator: exploring alternative stimulation sites and their stimulation efficiency.

    Directory of Open Access Journals (Sweden)

    Martin Grossöhmichen

    Full Text Available This work assesses the efficiency of the Codacs system actuator (Cochlear Ltd., Sydney Australia in different inner ear stimulation modalities. Originally the actuator was intended for direct perilymph stimulation after stapedotomy using a piston prosthesis. A possible alternative application is the stimulation of middle ear structures or the round window (RW. Here the perilymph stimulation with a K-piston through a stapes footplate (SFP fenestration (N = 10 as well as stimulation of the stapes head (SH with a Bell prosthesis (N = 9, SFP stimulation with an Omega/Aerial prosthesis (N = 8 and reverse RW stimulation (N = 10 were performed in cadaveric human temporal bones (TBs. Codacs actuator output is expressed as equivalent sound pressure level (eq. SPL using RW and SFP displacement responses, measured by Laser Doppler velocimetry as reference. The axial actuator coupling force in stimulation of stapes and RW was adjusted to ~5 mN. The Bell prosthesis and Omega/Aerial prosthesis stimulation generated similar mean eq. SPLs (Bell: 127.5-141.8 eq. dB SPL; Omega/Aerial: 123.6-143.9 eq. dB SPL, being significantly more efficient than K-piston perilymph stimulation (108.6-131.6 eq. dB SPL and RW stimulation (108.3-128.2 eq. dB SPL. Our results demonstrate that SH, SFP and RW are adequate alternative stimulation sites for the Codacs actuator using coupling prostheses and an axial coupling force of ~5 mN. Based on the eq. SPLs, all investigated methods were adequate for in vivo hearing aid applications, provided that experimental conditions including constant coupling force will be implemented.

  11. Fabrication of ruthemium 106 sources for betatherapy of choroid cancer

    International Nuclear Information System (INIS)

    Bourges, J.; Robelin, B.; Desmouliere, F.; Massicot, A.; Lefebre, D.

    1985-01-01

    Three sources of ruthenium 106 intended to the betatherapy of eye's tumours have been made by electrodeposition on stainless steel supports prior plated with gold 30 microns thick. This report presents the different steps of this preparation: ruthenium 106 purification from a solution of fission products by RuO 4 volatilization with AgO acting agent; gilding of the supports; ruthenium 106 electrodeposition as metal; protection of the source by a thin film of epoxyde resin [fr

  12. 13 CFR 108.885 - Disposition of assets to NMVC Company's Associates.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Disposition of assets to NMVC Company's Associates. 108.885 Section 108.885 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL (âNMVCâ) PROGRAM Financing of Small Businesses by NMVC Companies...

  13. 41 CFR 101-1.108 - Agency implementation and supplementation of FPMR.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Agency implementation and supplementation of FPMR. 101-1.108 Section 101-1.108 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 1-INTRODUCTION 1.1-Regulation...

  14. Thermal stability of the C106 dye in robust electrolytes

    DEFF Research Database (Denmark)

    Lund, Torben; Phuong, Nguyen Tuyet; Pechy, Peter

    -MPN) introduced by Gao et al. in 2008. [1]. Figure 1 Thermal degradation of C106 bound to TiO2 at 80 ºC in dark as a function of heating time. ● C106 = RuLL´(NCS)2 ■ RuLL´(NCS)(NBB)+ ▲ RuLL´(NCS)(3-MPN)+ The C106 dye was attached to the surface of TiO2 nano-particles and stable colloidal solutions...... of the particles were prepared in electrolyte mixture B. The solutions were thermally treated at 80 ◦C for 0-2000 hours followed by dye extraction and analysis by HPLC coupled to UV/Vis and electro spray mass spectrometry [2]. Figure 1 shows the concentration profiles of C106 samples prepared under ambient...... and glove box conditions as a function of the heating time. Preparation of the samples under strict atmospheric moisture control in a glove box gives the best results with a steady state surface concentration of 80% intact C106 and 20% NBB substitution product after ~1500 hours of heating at 80 ºC. If dye...

  15. Vapor space characterization of Waste Tank 241-U-106 (in situ): Results from samples collected on 8/25/94

    International Nuclear Information System (INIS)

    Ligotke, M.W.; Lucke, R.B.; Pool, K.H.

    1995-10-01

    This report describes inorganic and organic analyses results from in situ samples obtained from the headspace of the Hanford waste storage Tank 241-U-106 (referred to as Tank U-106). The results described here were obtained to support safety and toxicological evaluations. A summary of the results for inorganic and organic analytes is listed in Table 1. Detailed descriptions of the results appear in the text. Quantitative results were obtained for the inorganic compounds ammonia (NH 3 ), nitrogen dioxide (NO 2 ), nitric oxide (NO), and water (H 2 O). Sampling for hydrogen cyanide (HCN) and sulfur oxides (SO x ) was not performed. In addition, the authors looked for the 39 TO-14 compounds plus an additional 14 target analytes. Of these, six were observed above the 5-ppbv reporting cutoff. Ten organic tentatively identified compounds (TICs) were observed above the reporting cutoff of (ca.) 10 ppbv in two or more of the three samples collected and are reported with concentrations that are semiquantitative estimates based on internal standard response factors. The 10 organic analytes with the highest estimated concentrations are listed in Table 1 and account for approximately 89% of the total organic components in Tank U-106. Methyl isocyanate, a compound of possible concern in Tank U-106, was not detected. Tank U-106 is on the Organic Watch List

  16. 46 CFR 108.419 - Fire main capacity.

    Science.gov (United States)

    2010-10-01

    ... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems Fire Main System § 108.419 Fire main capacity. The diameter of the fire... pumps operating simultaneously. ...

  17. 20 CFR 422.108 - Criminal penalties.

    Science.gov (United States)

    2010-04-01

    ... connection with earnings records or for wrongful use or misrepresentation in connection with social security numbers, pursuant to section 208 of the Social Security Act and sections of title 18 U.S.C. (42 U.S.C. 408... Employees' Benefits SOCIAL SECURITY ADMINISTRATION ORGANIZATION AND PROCEDURES General Procedures § 422.108...

  18. 13 CFR 108.2030 - Matching requirements.

    Science.gov (United States)

    2010-01-01

    ... Section 108.2030 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL... resources raised by the NMVC Company or SSBIC. (b) Allowable sources. (1) Any source other than SBA is an... this part. (3) A portion of Private Capital may be designated as matching resources if the designated...

  19. 14 CFR 1221.106 - Establishment of the NASA Flag.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Establishment of the NASA Flag. 1221.106 Section 1221.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype, NASA...

  20. Cord blood banking activities at a university hospital in northeast Mexico: an 8-year experience.

    Science.gov (United States)

    Jaime-Perez, Jose C; Monreal-Robles, Roberto; Colunga-Pedraza, Julia; Mancías-Guerra, Consuelo; Rodríguez-Romo, Laura; Gómez-Almaguer, David

    2012-12-01

    Umbilical cord blood (UCB) represents an alternative source of stem cells for transplantation for the treatment of hematologic malignancies and genetic disorders. There is scarce information detailing cord blood bank (CBB) collection and transplantation activities from developing countries. We documented our experience at a public university hospital in northeast Mexico. We carried out a retrospective and descriptive analysis of our CBB activity during an 8-year period from May 2002 to September 2010. Collection, processing, and cryopreservation of CB were carried out following standard operating procedures. The minimum volume and total nucleated cell (TNC) content for cryopreservation were 80 mL and 8.0 × 10(8) , respectively. A total of 1256 UCB units were collected; 428 (34%) were banked and 828 (66%) were discarded. The main reason for exclusion was biologic: low volume and/or low number of TNC accounted for 84% of the total discarded units. Cryopreserved cord blood units (CBUs) had a median volume of 113.8 mL (range, 80-213.2 mL) and 13.0 × 10(8) (range, 8 × 10(8) -36.6 × 10(8) ) TNCs. Cell viability was 99.3% (88-100%). The median CD34+ cell content was 4.0 × 10(6) (0.46 × 10(6) -19.38 × 10(6) ). Sixteen units have been released for transplantation, leading to a utilization rate of 3.7%. CBB demands considerable human and financial resources; it is then essential for centers at developing countries to share their experience, results, and databases to increase the probability of finding matching units for their patients. Efforts to create and maintain CBBs allow to offer this therapeutic option at an affordable cost. © 2012 American Association of Blood Banks.

  1. The Plant Decapeptide OSIP108 Can Alleviate Mitochondrial Dysfunction Induced by Cisplatin in Human Cells

    Directory of Open Access Journals (Sweden)

    Pieter Spincemaille

    2014-09-01

    Full Text Available We investigated the effect of the Arabidopsis thaliana-derived decapeptide OSIP108 on human cell tolerance to the chemotherapeutic agent cisplatin (Cp, which induces apoptosis and mitochondrial dysfunction. We found that OSIP108 increases the tolerance of HepG2 cells to Cp and prevents Cp-induced changes in basic cellular metabolism. More specifically, we demonstrate that OSIP108 reduces Cp-induced inhibition of respiration, decreases glycolysis and prevents Cp-uptake in HepG2 cells. Apart from its protective action against Cp in human cells, OSIP108 also increases the yeast Saccharomyces cerevisiae tolerance to Cp. A limited yeast-based study of OSIP108 analogs showed that cyclization does not severely affect its activity, which was further confirmed in HepG2 cells. Furthermore, the similarity in the activity of the D-stereoisomer (mirror image form of OSIP108 with the L-stereoisomer suggests that its mode of action does not involve binding to a stereospecific receptor. In addition, as OSIP108 decreases Cp uptake in HepG2 cells and the anti-Cp activity of OSIP108 analogs without free cysteine is reduced, OSIP108 seems to protect against Cp-induced toxicity only partly via complexation. Taken together, our data indicate that OSIP108 and its cyclic derivatives can protect against Cp-induced toxicity and, thus, show potential as treatment options for mitochondrial dysfunction- and apoptosis-related conditions.

  2. 5 CFR 891.106 - Reconsideration.

    Science.gov (United States)

    2010-01-01

    ... FEDERAL EMPLOYEES HEALTH BENEFITS Administration and General Provisions § 891.106 Reconsideration. (a) Who may file. A retired employee may request OPM to reconsider its initial decision that he/she is not... control from making the request within the time limit. (e) Final decision. After reconsideration, OPM...

  3. 21 CFR 101.108 - Temporary exemptions for purposes of conducting authorized food labeling experiments.

    Science.gov (United States)

    2010-04-01

    ... authorized food labeling experiments. 101.108 Section 101.108 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION FOOD LABELING Exemptions From Food Labeling Requirements § 101.108 Temporary exemptions for purposes of conducting authorized food...

  4. C-106 tank process ventilation test

    International Nuclear Information System (INIS)

    Bailey, J.W.

    1998-01-01

    Project W-320 Acceptance Test Report for tank 241-C-106, 296-C-006 Ventilation System Acceptance Test Procedure (ATP) HNF-SD-W320-012, C-106 Tank Process Ventilation Test, was an in depth test of the 296-C-006 ventilation system and ventilation support systems required to perform the sluicing of tank C-106. Systems involved included electrical, instrumentation, chiller and HVAC. Tests began at component level, moved to loop level, up to system level and finally to an integrated systems level test. One criteria was to perform the test with the least amount of risk from a radioactive contamination potential stand point. To accomplish this a temporary configuration was designed that would simulate operation of the systems, without being connected directly to the waste tank air space. This was done by blanking off ducting to the tank and connecting temporary ducting and an inlet air filter and housing to the recirculation system. This configuration would eventually become the possible cause of exceptions. During the performance of the test, there were points where the equipment did not function per the directions listed in the ATP. These events fell into several different categories. The first and easiest problems were field configurations that did not match the design documentation. This was corrected by modifying the field configuration to meet design documentation and reperforming the applicable sections of the ATP. A second type of problem encountered was associated with equipment which did not operate correctly, at which point an exception was written against the ATP, to be resolved later. A third type of problem was with equipment that actually operated correctly but the directions in the ATP were in error. These were corrected by generating an Engineering Change Notice (ECN) against the ATP. The ATP with corrected directions was then re-performed. A fourth type of problem was where the directions in the ATP were as the equipment should operate, but the design of

  5. CD36 participates in PrP(106-126-induced activation of microglia.

    Directory of Open Access Journals (Sweden)

    Mohammed Kouadir

    Full Text Available Microglial activation is a characteristic feature of the pathogenesis of prion diseases. The molecular mechanisms that underlie prion-induced microglial activation are not very well understood. In the present study, we investigated the role of the class B scavenger receptor CD36 in microglial activation induced by neurotoxic prion protein (PrP fragment 106-126 (PrP(106-126. We first examined the time course of CD36 mRNA expression upon exposure to PrP(106-126 in BV2 microglia. We then analyzed different parameters of microglial activation in PrP(106-126-treated cells in the presence or not of anti-CD36 monoclonal antibody (mAb. The cells were first incubated for 1 h with CD36 monoclonal antibody to block the CD36 receptor, and were then treated with neurotoxic prion peptides PrP(106-126. The results showed that PrP(106-126 treatment led to a rapid yet transitory increase in the mRNA expression of CD36, upregulated mRNA and protein levels of proinflammatory cytokines (IL-1β, IL-6 and TNF-α, increased iNOS expression and nitric oxide (NO production, stimulated the activation of NF-κB and caspase-1, and elevated Fyn activity. The blockade of CD36 had no effect on PrP(106-126-stimulated NF-κB activation and TNF-α protein release, abrogated the PrP(106-126-induced iNOS stimulation, downregulated IL-1β and IL-6 expression at both mRNA and protein levels as well as TNF-α mRNA expression, decreased NO production and Fyn phosphorylation, reduced caspase-1 cleavage induced by moderate PrP(106-126-treatment, but had no effect on caspase-1 activation after treatment with a high concentration of PrP(106-126. Together, these results suggest that CD36 is involved in PrP(106-126-induced microglial activation and that the participation of CD36 in the interaction between PrP(106-126 and microglia may be mediated by Src tyrosine kinases. Our findings provide new insights into the mechanisms underlying the activation of microglia by neurotoxic prion peptides

  6. 34 CFR 106.41 - Athletics.

    Science.gov (United States)

    2010-07-01

    ... NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Education Programs or Activities Prohibited § 106.41 Athletics. (a) General...) Opportunity to receive coaching and academic tutoring; (6) Assignment and compensation of coaches and tutors...

  7. 14 CFR 1203b.106 - Use of deadly force.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Use of deadly force. 1203b.106 Section... AUTHORITY AND USE OF FORCE BY NASA SECURITY FORCE PERSONNEL § 1203b.106 Use of deadly force. Deadly force shall be used only in those circumstances where the security force officer reasonably believes that...

  8. Transfer from soil to plants of 106Ru as nitrosyl and as chloride

    International Nuclear Information System (INIS)

    Handl, J.

    1988-01-01

    The transfer of 106 Ru in a soil-plant ecosystem was investigated with respect to two chemical forms in compact soil samples under greenhouse conditions with surface and deep-layer contamination. Considerable differences in the uptake of 106 Ru were observed between 106 RuCl3 and 106 Ru-nitrosyl during the first 5-8 wk after the contamination of the soil. The translocation of 106 Ru in the soil showed an inhomogeneous distribution of the radioruthenium, with a great part of the total activity remaining in the upper soil layer between 0 and 5 cm even 10 mo after contamination of the soil surface. During the whole experiment, reemission of 106 Ru into the air was investigated by using special air collectors under different temperature and light conditions. Although a continuous checking out for a time of about 8 mo, no measurable concentrations of 106 Ru could be out for a time of about 8 mo, no measurable concentrations of 106 Ru could be found in examined air filters

  9. 13 CFR 106.500 - What is SBA's Gift authority?

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What is SBA's Gift authority? 106... AND NON-FEE BASED SBA-SPONSORED ACTIVITIES AND GIFTS Gifts § 106.500 What is SBA's Gift authority? This section covers SBA's Gift acceptance authority under sections 4(g), 8(b)(1)(G), 5(b)(9) and 7(k)(2...

  10. Collective dipole motion in highly excited (272)Hs (Z=108) nuclei

    NARCIS (Netherlands)

    Tveter, TS; Gaardhoje, JJ; Maj, A; Ramsay, T; Atac, A; Bacelar, J; Bracco, A; Buda, A; Camera, F; Herskind, B; Korten, W; Krolas, W; Menthe, A; Million, B; Nifenecker, H; Pignanelli, M; Pinston, JA; vanderPloeg, H; Schussler, F; Sletten, G

    1996-01-01

    The heavy nucleus (272)(108)Hs (Z = 108) and its evaporation daughters were produced using the reaction Th-232(Ar-40, gamma xn) with beam energies 10.5 and 15.0 MeV/A. The giant dipole resonance gamma radiation from the hot composite system prior to fission has been isolated using a differential

  11. Tank 241-BY-108 vapor sampling and analysis tank characterization report

    International Nuclear Information System (INIS)

    Huckaby, J.L.

    1995-01-01

    Tank BY-108 headspace gas and vapor samples were collected and analyzed to help determine the potential risks to tank farm workers due to fugitive emissions from the tank. Tank BY-108 is on the Ferrocyanide Watch List. Samples were collected from Tank BY-108 using the vapor sampling system (VSS) on october 27, 1994 by WHC Sampling and Mobile Laboratories. The tank headspace temperature was determined to be 25.7 C. Air from the Tank BY-108 headspace was withdrawn via a 7.9 m-long heated sampling probe mounted in riser 1, and transferred via heated tubing to the VSS sampling manifold. All heated zones of the VSS were maintained at approximately 50 C. Sampling media were prepared and analyzed by WHC, Oak Ridge National Laboratories, and Pacific Northwest Laboratories. The 40 tank air samples and 2 ambient air control samples collected are listed in Table X-1 by analytical laboratory. Table X-1 also lists the 14 trip blanks and 2 field blanks that accompanied the samples

  12. 50 CFR 20.106 - Seasons, limits, and shooting hours for sandhill cranes.

    Science.gov (United States)

    2010-10-01

    ... sandhill cranes. 20.106 Section 20.106 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE..., and Shooting Hours Schedules § 20.106 Seasons, limits, and shooting hours for sandhill cranes. This section provides for the annual hunting of sandhill cranes in designated portions of the 48 contiguous...

  13. 34 CFR 106.2 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... Introduction § 106.2 Definitions. As used in this part, the term: (a) Title IX means title IX of the Education... or political subdivision thereof, or any instrumentality of a State or political subdivision thereof... study beyond the bachelor of arts or bachelor of science degree, whether or not leading to a certificate...

  14. C-106 tank sluicer control system

    International Nuclear Information System (INIS)

    Bellomy, J.R.

    1997-01-01

    Acceptance Test Report for the Sluicer Control System, Project W-320 This Acceptance Test Procedure (ATP) has been prepared to demonstrate that the C-Farm tank C-106 sluicer functions as required by the design criteria

  15. 34 CFR 106.54 - Compensation.

    Science.gov (United States)

    2010-07-01

    ... employees of one sex at a rate less than that paid to employees of the opposite sex for equal work on jobs... NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs or Activities Prohibited § 106.54...

  16. Angina pectoris refractory for conventional therapy--is neurostimulation a possible alternative treatment?

    Science.gov (United States)

    Hautvast, R W; DeJongste, M J; ter Horst, G J; Blanksma, P K; Lie, K I

    1996-07-01

    The treatment of angina pectoris as a symptom of coronary artery disease usually is focused on restoring the balance between oxygen demand and supply of the myocardium by administration of drugs interfering in heart rate, cardiac pre- and afterload, and coronary vascular tone. For nonresponders to drug therapy or for those with jeopardized myocardium, revascularization procedures such as coronary bypass surgery and percutaneous transluminal coronary angioplasty are at hand. However, the atherosclerotic process is not stopped by these therapies and, at longer terms, angina may recur. It is not always possible to revascularize all the patients who do not positively react to medical treatment. Those with angina, not responding to adequate medication and who are not suitable anymore for revascularization, are considered to suffer from refractory angina pectoris. This group of patients has a poor quality of life, for their exercise tolerance is severely afflicted. For these patients, neurostimulation has been described repeatedly as an effective and safe therapy. The mechanism of action of neurostimulation is not completely known, but recent studies suggest an anti-ischemic effect, exerted through changes in myocardial blood flow. As soon as its safety is sufficiently established, it may become a useful alternative in the treatment of refractory angina pectoris.

  17. Visual acuity after Ruthenium106 brachytherapy of choroidal melanomas

    International Nuclear Information System (INIS)

    Damato, Bertil; Patel, Imran M.; Campbell, Ian R.; Mayles, Helen M.; Errington, R. Douglas

    2005-01-01

    Purpose: To report on conservation of visual acuity after Ruthenium 106 (Ru-106) brachytherapy of choroidal melanoma. Methods and materials: This study was a noncomparative interventional case series of 458 patients with choroidal melanoma treated at a single center between January 1993 and December 2001. The intervention consisted of Ru-106 brachytherapy delivering minimum scleral and apex doses of 300 Gy and 80 Gy, respectively, using a 15-mm or 20-mm plaque. For discrete, posterior tumors, the plaque was positioned eccentrically with its posterior edge aligned with the posterior tumor margin. To ensure correct plaque positioning, any overlying extraocular muscles were dis-inserted, and the locations of both tumor and plaque edges were confirmed by transillumination and indentation. The main outcome measures were conservation of vision of 20/40 or better, 20/200 or better, and Counting Fingers or better, according to baseline variables. Results: The actuarial rate of conservation of 20/40 or better was 55% at 9 years, loss of such vision correlating with posterior tumor extension (p 106 brachytherapy of posterior choroidal melanoma achieves good conservation of vision if the tumor does not extend close to the optic nerve or fovea

  18. Study on corrosion resistance of A106Gr.B and A672Gr.B60 in dynamic water loop with high temperature and pressure

    International Nuclear Information System (INIS)

    Tian Jue; Wang Hui; Li Xinmin

    2014-01-01

    Due to the low carbon and low alloy Cr content, flow accelerates corrosion prone to have a serious impact on safety. AP1000 is the most advanced nuclear power technology in recent years. The plant used A672Gr.B60 as an alternative feed pipe to reduce the impact of flow accelerated corrosion. The impact of different flow rates, alkaline agent type and material property on A672Gr.B60 and A106Gr.B were characterized by scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy (EDS) and X-ray photoelectronic spectroscopy (XPS). After 336 h experiments were conducted, results show that the corrosion rate of A672Gr.B60 is much lower than that of A106Gr.B, and the density of oxidation film on A672Gr.B60 is superior to A106Gr.B. Ethanolamine (ETA) as an alkaline agent is better to reduce FAC to A106Gr.B, and it also can make the oxidation film become denser. Changes in flow rate will affect the size, shape and distribution of the oxide particles, and will also affect the thickness of the oxide film. Both of two materials were composed by Fe 3 O 4 . (authors)

  19. The Alternative complex III: properties and possible mechanisms for electron transfer and energy conservation.

    Science.gov (United States)

    Refojo, Patrícia N; Teixeira, Miguel; Pereira, Manuela M

    2012-10-01

    Alternative complexes III (ACIII) are recently identified membrane-bound enzymes that replace functionally the cytochrome bc(1/)b(6)f complexes. In general, ACIII are composed of four transmembrane proteins and three peripheral subunits that contain iron-sulfur centers and C-type hemes. ACIII are built by a combination of modules present in different enzyme families, namely the complex iron-sulfur molybdenum containing enzymes. In this article a historical perspective on the investigation of ACIII is presented, followed by an overview of the present knowledge on these enzymes. Electron transfer pathways within the protein are discussed taking into account possible different locations (cytoplasmatic or periplasmatic) of the iron-sulfur containing protein and their contribution to energy conservation. In this way several hypotheses for energy conservation modes are raised including linear and bifurcating electron transfer pathways. This article is part of a Special Issue entitled: 17th European Bioenergetics Conference (EBEC 2012). Copyright © 2012 Elsevier B.V. All rights reserved.

  20. The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes

    Science.gov (United States)

    Schwenk, Benjamin M; Lang, Christina M; Hogl, Sebastian; Tahirovic, Sabina; Orozco, Denise; Rentzsch, Kristin; Lichtenthaler, Stefan F; Hoogenraad, Casper C; Capell, Anja; Haass, Christian; Edbauer, Dieter

    2014-01-01

    TMEM106B is a major risk factor for frontotemporal lobar degeneration with TDP-43 pathology. TMEM106B localizes to lysosomes, but its function remains unclear. We show that TMEM106B knockdown in primary neurons affects lysosomal trafficking and blunts dendritic arborization. We identify microtubule-associated protein 6 (MAP6) as novel interacting protein for TMEM106B. MAP6 over-expression inhibits dendritic branching similar to TMEM106B knockdown. MAP6 knockdown fully rescues the dendritic phenotype of TMEM106B knockdown, supporting a functional interaction between TMEM106B and MAP6. Live imaging reveals that TMEM106B knockdown and MAP6 overexpression strongly increase retrograde transport of lysosomes in dendrites. Downregulation of MAP6 in TMEM106B knockdown neurons restores the balance of anterograde and retrograde lysosomal transport and thereby prevents loss of dendrites. To strengthen the link, we enhanced anterograde lysosomal transport by expressing dominant-negative Rab7-interacting lysosomal protein (RILP), which also rescues the dendrite loss in TMEM106B knockdown neurons. Thus, TMEM106B/MAP6 interaction is crucial for controlling dendritic trafficking of lysosomes, presumably by acting as a molecular brake for retrograde transport. Lysosomal misrouting may promote neurodegeneration in patients with TMEM106B risk variants. PMID:24357581

  1. Analysis and characterization of double shell tank 241-AP-108

    International Nuclear Information System (INIS)

    Miller, G.L.

    1994-01-01

    This document is the first part of a three-part report describing the analysis and characterization of double shell tank 241-AP-108 which is located at the Hanford Reservation.This document is the analytical laboratory data package entitled 'Analysis and Characterization of Double Shell Tank 241-AP-108' which contains a case sampling history, the sampling protocols, the analytical procedures, sampling and analysis quality assurance and quality control measures, and chemical analysis results for samples obtained from the tank

  2. Quantifying key parameters as elicitors for alternate fruit bearing in cv. 'Elstar' apple trees.

    Science.gov (United States)

    Krasniqi, Anne-Lena; Damerow, Lutz; Kunz, Achim; Blanke, Michael M

    2013-11-01

    The commonly known alternate bearing, i.e. year-to-year change of large and small yields of fruit tree crops worldwide, is often induced by abiotic stress such as late frost, which will eliminate flowers or fruitlets. This study presents an alternative form, biotic biennial bearing, i.e. change of large and small yields of the same trees within the same tree row in the same year. Three methods were developed or modified for the analysis of the number of flower clusters and yield of 2086 apple (Malus domestica Borkh.) cv. 'Elstar' trees. The first method, i.e., based on intersect between yield in year x and year x+1 and flower clusters in year x, yielded 91-106 flower clusters, whereas the second method, i.e., mean yield in year x and year x+1, resulted in a range of 72-133 flower clusters, or 9.6kg/tree necessary for sustainable cultivation of apple cv. 'Elstar'. The third 'biennial bearing index' (BBI), was calculated in three ways as the ratio of differences in tree yields to cumulative tree yield, for individual trees (rather than orchard average) to demonstrate the tree-to-tree alternation. A scheme for the possible underlying regulatory mechanisms was developed, which includes potential elicitors such as light deprivation and subsequent lack of flower initiation, are discussed as a possible result of polar basipetal GA7 transport, cytokinin level in the xylem and phloem and down-regulation of the gene expression of the flowering gene. Suggested countermeasures included early chemical or mechanical thinning. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  3. 40 CFR 180.1253 - Streptomyces lydicus WYEC 108; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Streptomyces lydicus WYEC 108... RESIDUES IN FOOD Exemptions From Tolerances § 180.1253 Streptomyces lydicus WYEC 108; exemption from the... the microbial pesticide Streptomyces lydicus WYEC 108 when used in or on all agricultural commodities...

  4. 9 CFR 108.5 - Preparation of legends.

    Science.gov (United States)

    2010-01-01

    ... 108.5 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF.... Legends shall be provided for each plot plan and each blueprint or drawing. All pages of the legends shall be numbered, identified with corresponding plot plan or blueprint, and submitted in booklet form...

  5. Decay properties of nuclei close to Z = 108 and N = 162

    Energy Technology Data Exchange (ETDEWEB)

    Dvorak, Jan

    2007-07-12

    The goal of the research conducted in the frame of this thesis was to investigate the decay properties of the nuclides {sup 269-271}Hs and their daughters using an improved chemical separation and detection system. Shell stabilization was predicted in the region around Z=108 and N=162 in calculations, taking into account possible higher orders of deformations of the nuclei. The nucleus {sup 270}Hs with a closed proton and a closed neutron deformed shell, was predicted to be ''deformed doubly magic''. Nuclei around {sup 270}Hs can be produced only via fusion reactions at picobarn levels, resulting in a production rates of few atoms per day. Investigating short-lived nuclei using rapid chemical separation and subsequent on-line detection methods provides an independent and alternative means to electromagnetic on-line separators. Chemical separation of Hs in the form of HsO{sub 4} provides an excellent tool to study the formation reactions and nuclear structure in this region of the chart of nuclides due to a high overall efficiency and a very high purification factor. The goal was accomplished, as element 108, hassium, was produced in the reaction {sup 248}Cm({sup 26}Mg,xn){sup 274-x}Hs and chemically isolated. After gas phase separation of HsO{sub 4}, 26 genetically linked decay chains have been observed. These were attributed to decays of three different Hs isotopes produced in the 3-5n evaporation channels. The known decay chain of {sup 269}Hs, the 5n evaporation product, serves as an anchor point, thus allowing the unambiguous assignment of the observed decay chains to the 5n, 4n, and 3n channels, respectively. Decay properties of five nuclei have been unambiguously established for the first time, including the one for the the doubly-magic nuclide {sup 270}Hs. This hassium isotope is the next doubly magic nucleus after the well known {sup 208}Pb and the first experimentally observed even-even nucleus on the predicted N=162 neutron shell. The

  6. 13 CFR 108.340 - Evaluation and selection-general.

    Science.gov (United States)

    2010-01-01

    ... VENTURE CAPITAL (âNMVCâ) PROGRAM Evaluation and Selection of NMVC Companies § 108.340 Evaluation and... Applicants in such a way as to promote Developmental Venture Capital investments nationwide and in both urban...

  7. 34 CFR 106.39 - Health and insurance benefits and services.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Health and insurance benefits and services. 106.39... Prohibited § 106.39 Health and insurance benefits and services. In providing a medical, hospital, accident, or life insurance benefit, service, policy, or plan to any of its students, a recipient shall not...

  8. 24 CFR 108.20 - Monitoring office responsibility for monitoring plans and reports.

    Science.gov (United States)

    2010-04-01

    ... documenting the implementation of the AFHM plan, including sales or rental reports, as required by the.... When sales or rental reports show that 20% of the units covered by the AFHM plan have been sold or... for monitoring plans and reports. 108.20 Section 108.20 Housing and Urban Development Regulations...

  9. 5 CFR 335.106 - Special selection procedures for certain veterans under merit promotion.

    Science.gov (United States)

    2010-01-01

    ... veterans under merit promotion. 335.106 Section 335.106 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROMOTION AND INTERNAL PLACEMENT General Provisions § 335.106 Special selection procedures for certain veterans under merit promotion. Preference eligibles or veterans who have...

  10. 106-17 Telemetry Standards Chapter 1

    Science.gov (United States)

    2017-07-01

    Telemetry Standards, RCC Standard 106-17 Chapter 1, July 2017 1-1 CHAPTER 1 Introduction The Telemetry Standards address the here-to-date...for Federal Radio Frequency Management . Copies of that manual may be obtained from: Executive Secretary, Interdepartmental Radio Advisory Committee

  11. Final characterization report for the 108-F Biological Laboratory

    International Nuclear Information System (INIS)

    Harris, R.A.

    1996-09-01

    This report provides a compilation of characterization data for the 108-F Biological Laboratory collected during the period of May 7, 1996 through August 29, 1996. The 108-F Biology Laboratory is located on the Hanford Site in Richland, Washington. The characterization activities were organized and implemented to evaluate the radiological status of the laboratory and to identify hazardous materials. This report reflects the current conditions and status of the laboratory. Information in this report is intended to be utilized to prepare an accurate cost estimate for building demolition, to aid in planning decontamination and demolition activities, and allow proper disposal of demolition debris

  12. Frequency of the ATM IVS10-6T→G variant in Australian multiple-case breast cancer families

    International Nuclear Information System (INIS)

    Lindeman, Geoffrey J; Suthers, Graeme; Kirk, Judy; Hiew, Melody; Visvader, Jane E; Leary, Jennifer; Field, Michael; Gaff, Clara L; Gardner, RJ McKinlay; Trainor, Kevin; Cheetham, Glenice

    2004-01-01

    Germline mutations in the genes BRCA1 and BRCA2 account for only a proportion of hereditary breast cancer, suggesting that additional genes contribute to hereditary breast cancer. Recently a heterozygous variant in the ataxia–telangiectasia mutated (ATM) gene, IVS10-6T→G, was reported by an Australian multiple-case breast cancer family cohort study (the Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer) to confer a substantial breast cancer risk. Although this variant can result in a truncated ATM product, its clinical significance as a high-penetrance breast cancer allele or its role as a low-penetrance risk-modifier is controversial. We determined the frequency of ATM IVS10-6T→G variants in a cohort of individuals affected by breast and/or ovarian cancer who underwent BRCA1 and BRCA2 genetic testing at four major Australian familial cancer clinics. Seven of 495 patients (1.4%) were heterozygous for the IVS10-6T→G variant; the carrier rate in unselected Australian women with no family history of breast cancer is reported to be 6 of 725 (0.83%) (P = 0.4). Two of the seven probands also harboured a pathogenic BRCA1 mutation and one patient had a BRCA1 unclassified variant of uncertain significance. These findings indicate that the ATM IVS10-6T→G variant does not seem to occur at a significantly higher frequency in affected individuals from high-risk families than in the general population. A role for this variant as a low-penetrance allele or as a modifying gene in association with other genes (such as BRCA1) remains possible. Routine testing for ATM IVS10-6T→G is not warranted in mutation screening of affected individuals from high-risk families

  13. Usefulness of Photodynamic Therapy as a Possible Therapeutic Alternative in the Treatment of Basal Cell Carcinoma

    Directory of Open Access Journals (Sweden)

    Paola Savoia

    2015-09-01

    Full Text Available Basal cell carcinoma (BCC is the most common cancer in individuals with fair skin type (I–II and steadily increasing in incidence (70% of skin malignancy. It is locally invasive but metastasis is usually very rare, with an estimated incidence of 0.0028%–0.55%. Conventional therapy is surgery, especially for the H region of the face and infiltrative lesions; in case of inoperable tumors, radiotherapy is a valid option. Recently, topical photodynamic therapy (PDT has become an effective treatment in the management of superficial and small nodular BCC. PDT is a minimally invasive procedure that involves the administration of a photo-sensibilizing agent followed by irradiation at a pre-defined wavelength; this determines the creation of reactive oxygen species that specifically destroy target cells. The only major side effect is pain, reported by some patients during the irradiation. The high cure rate and excellent cosmetic outcome requires considering this possibility for the management of patients with both sporadic and hereditary BCC. In this article, an extensive review of the recent literature was made, in order to clarify the role of PDT as a possible alternative therapeutic option in the treatment of BCC.

  14. Usefulness of Photodynamic Therapy as a Possible Therapeutic Alternative in the Treatment of Basal Cell Carcinoma

    Science.gov (United States)

    Savoia, Paola; Deboli, Tommaso; Previgliano, Alberto; Broganelli, Paolo

    2015-01-01

    Basal cell carcinoma (BCC) is the most common cancer in individuals with fair skin type (I–II) and steadily increasing in incidence (70% of skin malignancy). It is locally invasive but metastasis is usually very rare, with an estimated incidence of 0.0028%–0.55%. Conventional therapy is surgery, especially for the H region of the face and infiltrative lesions; in case of inoperable tumors, radiotherapy is a valid option. Recently, topical photodynamic therapy (PDT) has become an effective treatment in the management of superficial and small nodular BCC. PDT is a minimally invasive procedure that involves the administration of a photo-sensibilizing agent followed by irradiation at a pre-defined wavelength; this determines the creation of reactive oxygen species that specifically destroy target cells. The only major side effect is pain, reported by some patients during the irradiation. The high cure rate and excellent cosmetic outcome requires considering this possibility for the management of patients with both sporadic and hereditary BCC. In this article, an extensive review of the recent literature was made, in order to clarify the role of PDT as a possible alternative therapeutic option in the treatment of BCC. PMID:26426005

  15. Study of the optimal reaction conditions for assay of the mouse alternative complement pathway

    NARCIS (Netherlands)

    Dijk, H. van; Rademaker, P.M.; Klerx, J.P.A.M.; Willers, J.M.M.

    1985-01-01

    The optimal reaction conditions for hemolytic assay of alternative complement pathway activity in mouse serum were investigated. A microtiter system was used, in which a number of 7.5×106 rabbit erythrocytes per test well appeared to be optimal. Rabbit erythrocytes were superior as target cells over

  16. 42 CFR 3.106 - Security requirements.

    Science.gov (United States)

    2010-10-01

    ... ORGANIZATIONS AND PATIENT SAFETY WORK PRODUCT PSO Requirements and Agency Procedures § 3.106 Security requirements. (a) Application. A PSO must secure patient safety work product in conformance with the security... the confidentiality and security of patient safety work product. (2) Distinguishing patient safety...

  17. 46 CFR 108.443 - Controls and valves.

    Science.gov (United States)

    2010-10-01

    ... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Fire Extinguishing Systems Fixed Carbon Dioxide Fire Extinguishing Systems § 108.443 Controls and valves. (a) At least one control for operating a CO2 system must be outside the space or spaces that the...

  18. 13 CFR 108.50 - Definition of terms.

    Science.gov (United States)

    2010-01-01

    ... the Small Business Act and 13 CFR 126.103; (ii) An Urban Empowerment Zone or Urban Enterprise... Capital Investment in a Low-Income Enterprise. Management Expenses has the meaning set forth in § 108.520... Assistance means management, marketing, and other technical assistance that assists a Small Business with its...

  19. 13 CFR 108.310 - Contents of application.

    Science.gov (United States)

    2010-01-01

    ... Section 108.310 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL... Applicant must indicate— (1) The specific amount of Regulatory Capital it proposes to raise (which amount... of which must be not less than $1,500,000 or 30 percent of the Regulatory Capital it proposes to...

  20. 20 CFR 10.6 - What special statutory definitions apply to dependents and survivors?

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false What special statutory definitions apply to dependents and survivors? 10.6 Section 10.6 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS...' COMPENSATION ACT, AS AMENDED General Provisions Definitions and Forms § 10.6 What special statutory definitions...

  1. 15 CFR 270.106 - Conflicts of interest related to service on a Team.

    Science.gov (United States)

    2010-01-01

    ... service on a Team. 270.106 Section 270.106 Commerce and Foreign Trade Regulations Relating to Commerce and... SAFETY TEAMS NATIONAL CONSTRUCTION SAFETY TEAMS Establishment and Deployment of Teams § 270.106 Conflicts of interest related to service on a Team. (a) Team members who are not Federal employees will be...

  2. 41 CFR 301-71.108 - What internal policies and procedures must we establish for travel authorization?

    Science.gov (United States)

    2010-07-01

    ... and procedures must we establish for travel authorization? 301-71.108 Section 301-71.108 Public Contracts and Property Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES AGENCY RESPONSIBILITIES 71-AGENCY TRAVEL ACCOUNTABILITY REQUIREMENTS Travel Authorization § 301-71.108...

  3. Empirical estimation of astrophysical photodisintegration rates of 106Cd

    Science.gov (United States)

    Belyshev, S. S.; Kuznetsov, A. A.; Stopani, K. A.

    2017-09-01

    It has been noted in previous experiments that the ratio between the photoneutron and photoproton disintegration channels of 106Cd might be considerably different from predictions of statistical models. The thresholds of these reactions differ by several MeV and the total astrophysical rate of photodisintegration of 106Cd, which is mostly produced in photonuclear reactions during the p-process nucleosynthesis, might be noticeably different from the calculated value. In this work the bremsstrahlung beam of a 55.6 MeV microtron and the photon activation technique is used to measure yields of photonuclear reaction products on isotopically-enriched cadmium targets. The obtained results are compared with predictions of statistical models. The experimental yields are used to estimate photodisintegration reaction rates on 106Cd, which are then used in nuclear network calculations to examine the effects of uncertainties on the produced abundences of p-nuclei.

  4. Tank 241-C-106 in-tank imaging system operational test report

    International Nuclear Information System (INIS)

    Pedersen, L.T.

    1998-01-01

    This document presents the results of operational testing of the 241-C-106 In-Tank Video Camera Imaging System. This imaging system was installed as a component of Project W-320 to monitor sluicing and waste retrieval activities in Tank 241-C-106

  5. 26 CFR 521.106 - Control of a domestic enterprise by a Danish enterprise.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 19 2010-04-01 2010-04-01 false Control of a domestic enterprise by a Danish enterprise. 521.106 Section 521.106 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Are Residents of Denmark and of Danish Corporations § 521.106 Control of a domestic enterprise by a...

  6. 9 CFR 93.106 - Quarantine requirements.

    Science.gov (United States)

    2010-01-01

    ... Section 93.106 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF... other than ratites and hatching eggs of ratites. Each lot of pet birds, except as provided for in § 93.... (2) Physical plant requirements. The facility shall comply with the following requirements: (i...

  7. The plant decapeptide OSIP108 prevents copper-induced toxicity in various models for Wilson disease

    Energy Technology Data Exchange (ETDEWEB)

    Spincemaille, Pieter [Centre of Microbial and Plant Genetics (CMPG), KU Leuven, Kasteelpark Arenberg 20, 3001 Heverlee (Belgium); Pham, Duc-Hung [Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg, Herestraat 49, O and N2, 3000 Leuven (Belgium); Chandhok, Gursimran [Clinic for Transplantation Medicine, Münster University Hospital, Albert-Schweitzer-Campus 1, Building A14, D-48149 Münster (Germany); Verbeek, Jef [Department of Hepatology and Metabolic Center, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven (Belgium); Zibert, Andree [Clinic for Transplantation Medicine, Münster University Hospital, Albert-Schweitzer-Campus 1, Building A14, D-48149 Münster (Germany); Libbrecht, Louis [Department of Hepatology and Metabolic Center, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven (Belgium); Department of Pathology, University Hospital Ghent, De Pintelaan 185, 9000 Ghent (Belgium); Schmidt, Hartmut [Clinic for Transplantation Medicine, Münster University Hospital, Albert-Schweitzer-Campus 1, Building A14, D-48149 Münster (Germany); Esguerra, Camila V.; Witte, Peter A.M. de [Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg, Herestraat 49, O and N2, 3000 Leuven (Belgium); Cammue, Bruno P.A., E-mail: bruno.cammue@biw.kuleuven.be [Centre of Microbial and Plant Genetics (CMPG), KU Leuven, Kasteelpark Arenberg 20, 3001 Heverlee (Belgium); Department of Plant Systems Biology, VIB, Technologiepark 927, 9052 Ghent (Belgium); Cassiman, David [Department of Hepatology and Metabolic Center, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven (Belgium); Thevissen, Karin [Centre of Microbial and Plant Genetics (CMPG), KU Leuven, Kasteelpark Arenberg 20, 3001 Heverlee (Belgium)

    2014-10-15

    Background: Wilson disease (WD) is caused by accumulation of excess copper (Cu) due to a mutation in the gene encoding the liver Cu transporter ATP7B, and is characterized by acute liver failure or cirrhosis and neuronal cell death. We investigated the effect of OSIP108, a plant derived decapeptide that prevents Cu-induced apoptosis in yeast and human cells, on Cu-induced toxicity in various mammalian in vitro models relevant for WD and in a Cu-toxicity zebrafish larvae model applicable to WD. Methods: The effect of OSIP108 was evaluated on viability of various cell lines in the presence of excess Cu, on liver morphology of a Cu-treated zebrafish larvae strain that expresses a fluorescent reporter in hepatocytes, and on oxidative stress levels in wild type AB zebrafish larvae. Results: OSIP108 increased not only viability of Cu-treated CHO cells transgenically expressing ATP7B and the common WD-causing mutant ATP7B{sup H1069Q}, but also viability of Cu-treated human glioblastoma U87 cells. Aberrancies in liver morphology of Cu-treated zebrafish larvae were observed, which were further confirmed as Cu-induced hepatotoxicity by liver histology. Injections of OSIP108 into Cu-treated zebrafish larvae significantly increased the amount of larvae with normal liver morphology and decreased Cu-induced production of reactive oxygen species. Conclusions: OSIP108 prevents Cu-induced toxicity in in vitro models and in a Cu-toxicity zebrafish larvae model applicable to WD. General significance: All the above data indicate the potential of OSIP108 as a drug lead for further development as a novel WD treatment. - Highlights: • Wilson disease (WD) is characterized by accumulation of toxic copper (Cu). • OSIP108 increases viability of Cu-treated cellular models applicable to WD. • OSIP108 injections preserve liver morphology of Cu-treated zebrafish larvae. • OSIP108 injections into zebrafish larvae abrogates Cu-induced oxidative stress.

  8. 13 CFR 108.640 - Requirement to file portfolio financing reports (SBA Form 1031).

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Requirement to file portfolio financing reports (SBA Form 1031). 108.640 Section 108.640 Business Credit and Assistance SMALL BUSINESS... portfolio financing reports (SBA Form 1031). For each Financing you make (excluding guarantees), you must...

  9. 40 CFR 180.108 - Acephate; tolerances for residues.

    Science.gov (United States)

    2010-07-01

    ... establishments, including food service, manufacturing and processing establishments, such as restaurants... avoid atomization or splashing of the spray. Contamination of food or food-contact surfaces shall be... PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Specific Tolerances § 180.108...

  10. Biological insights from 108 schizophrenia-associated genetic loci

    DEFF Research Database (Denmark)

    Ripke, Stephan; Neale, Benjamin M.; Corvin, Aiden

    2014-01-01

    and 113,075 controls. We identify 128 independent associations spanning 108 conservatively defined loci that meet genome-wide significance, 83 of which have not been previously reported. Associations were enriched among genes expressed in brain, providing biological plausibility for the findings. Many...

  11. 13 CFR 108.130 - Identified Low Income Geographic Areas.

    Science.gov (United States)

    2010-01-01

    ... VENTURE CAPITAL (âNMVCâ) PROGRAM Qualifications for the NMVC Program Organizing A Nmvc Company § 108.130... intends to make Developmental Venture Capital investments and provide Operational Assistance under the...

  12. 48 CFR 1313.106 - Soliciting competition, evaluation of quotations or offers, award and documentation.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Soliciting competition, evaluation of quotations or offers, award and documentation. 1313.106 Section 1313.106 Federal Acquisition... PROCEDURES Procedures 1313.106 Soliciting competition, evaluation of quotations or offers, award and...

  13. 48 CFR 813.106 - Soliciting competition, evaluation of quotations or offers, award and documentation.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Soliciting competition, evaluation of quotations or offers, award and documentation. 813.106 Section 813.106 Federal Acquisition... ACQUISITION PROCEDURES Procedures 813.106 Soliciting competition, evaluation of quotations or offers, award...

  14. 34 CFR 106.3 - Remedial and affirmative action and self-evaluation.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Remedial and affirmative action and self-evaluation. 106.3 Section 106.3 Education Regulations of the Offices of the Department of Education OFFICE FOR.... (c) Self-evaluation. Each recipient education institution shall, within one year of the effective...

  15. Tank 241-C-108 vapor sampling and analysis tank characterization report

    International Nuclear Information System (INIS)

    Huckaby, J.L.

    1995-01-01

    Tank 241-C-108 headspace gas and vapor samples were collected and analyzed to help determine the potential risks to tank farm workers due to fugitive emissions from the tank. The drivers and objectives of waste tank headspace sampling and analysis are discussed in Program Plan for the Resolution of Tank Vapor Issues (Osborne and Huckaby 1994). Tank 241-C-108 was vapor sampled in accordance with Data Quality Objectives for Generic In-Tank Health and Safety Issue Resolution (Osborne et al., 1994)

  16. Detection of ruthenium 106 in France and in Europe. Results of IRSN's investigations. Information report (Update of report of 09/10/2017)

    International Nuclear Information System (INIS)

    2017-01-01

    Ruthenium 106 has been detected in late September by several European networks involved in the monitoring of atmospheric radioactive contamination, at levels of a few milli-Becquerels per cubic meter of air. IRSN's investigations make it possible to provide information on the possible location of the source of the release as well as the order of magnitude of the quantities released

  17. 13 CFR 108.160 - Special rules for NMVC Companies formed as limited partnerships.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Special rules for NMVC Companies formed as limited partnerships. 108.160 Section 108.160 Business Credit and Assistance SMALL BUSINESS... of a limited partner pending SBA's written approval of such transfer or succession; and (4) You must...

  18. 13 CFR 108.1610 - Effect of prepayment or early redemption of Leverage on a Trust Certificate.

    Science.gov (United States)

    2010-01-01

    ... Companies (Leverage) Funding Leverage by Use of Sba Guaranteed Trust Certificates (âtcsâ) § 108.1610 Effect... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Effect of prepayment or early redemption of Leverage on a Trust Certificate. 108.1610 Section 108.1610 Business Credit and Assistance SMALL...

  19. Baseline estimate of the retained gas volume in Tank 241-C-106

    International Nuclear Information System (INIS)

    Stewart, C.W.; Chen, G.

    1998-06-01

    This report presents the results of a study of the retained gas volume in Hanford Tank 241-C-106 (C-106) using the barometric pressure effect method. This estimate is required to establish the baseline conditions for sluicing the waste from C-106 into AY-102, scheduled to begin in the fall of 1998. The barometric pressure effect model is described, and the data reduction and detrending techniques are detailed. Based on the response of the waste level to the larger barometric pressure swings that occurred between October 27, 1997, and March 4, 1998, the best estimate and conservative (99% confidence) retained gas volumes in C-106 are 24 scm (840 scf) and 50 scm (1,770 scf), respectively. This is equivalent to average void fractions of 0.025 and 0.053, respectively

  20. 48 CFR 13.106 - Soliciting competition, evaluation of quotations or offers, award and documentation.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Soliciting competition, evaluation of quotations or offers, award and documentation. 13.106 Section 13.106 Federal Acquisition... ACQUISITION PROCEDURES Procedures 13.106 Soliciting competition, evaluation of quotations or offers, award and...

  1. Transfer and accumulation of 106Ru from phytoplankton (Dunaliella bioculata) to zooplankton (Artemia salina)

    International Nuclear Information System (INIS)

    Izumo, Yoshiro; Takase, Akira

    1982-01-01

    106 Ru is one of the most abundant radionuclides to be released from the unclear-spent fuel reprocessing plant to oceans. This paper deals with transfer and accumulation of the radionuclide from phytoplankton (Dunaliella) to zooplankton (Artemia) in the graizing food chain of marine organisms. Each plankton was reared in the radioactive sea water A (filtrated and circulated through sandy mud, and the radioactive concentration decreased and atteined to constant after addition of 106 Ru), B (not filtrated and circulated, and the radioactive concentration decreased and atteined to constant) and C (not filtrated and circulated, the radioactive concentration decreased, but did not attein to constant), respectively, and investigated accumulations of 106 Ru. Then, accumulations of 106 Ru in Artemia by the ingestion of each diet (Dunaliella) contaminated with 106 Ru in each water, were investigated and compared with those from each water. Concentration factors of 106 Ru for the planktons reared in the radioactive sea waters were different among these waters. The difference can be attributable to that of physicochemical states of 106 Ru in the waters. It was found that 106 Ru would be accumulated by Artemia from the water A about 10 times higher than from the contaminated diet (Dunaliella) in this water, however from the contaminated diet (Dunaliella) in the water B about 2.2 times higher than from the last water. (author)

  2. Cloning and characterization of the ONAC106 gene from Oryza sativa cultivar Kuku Belang

    Science.gov (United States)

    Basri, Khairunnisa; Sukiran, Noor Liyana; Zainal, Zamri

    2016-11-01

    Plants possess different mechanisms in stress response, where induction of stress-responsive genes provides tolerance to unfavorable conditions. Stress-responsive genes are characterized for functional and regulatory genes that help in overcoming stress by molecular, biochemical and morphological adaptations. NAC transcription factors are one of the regulatory proteins that involved in stress signaling pathway. A putative NAC transcription factor, ONAC016 was identified from drought transcriptomic data. Our data suggested that ONAC106 was induced by drought, but its function in abiotic stress is still unclear. In silico analysis of ONAC106 showed that this gene encodes 334 amino acids, and its protein consists of NAM (No Apical Meristem) domain. The orthologue of ONAC106 was present in several Poaceae family members, suggesting that ONAC106 is unique to monocot plants only. We found that ONAC106 was induced by salt and cold stresses, indicating that this gene involves in abiotic stress response. In addition, we also found that ONAC106 might function in defense response to pathogen invasion. The ABRE (Abscisic Acid Regulatory Element) cis-element was identified in the promoter region of ONAC106, suggesting that it may involve in the abscisic acid (ABA)-dependent signaling pathway. Based on this preliminary result, we hypothesize that ONAC106 may play a role in abiotic stress response by regulating ABA-responsive genes.

  3. Engineering evaluation cost analysis for the 100-B/C area ancillary facilities at the 108-F Building

    International Nuclear Information System (INIS)

    1996-10-01

    In 1995, the US Department of Energy (DOE), Richland Operations Office (RL) conducted a removal site evaluation of selected facilities in the 100 Area of the Hanford Site in accordance with CERCLA and 40 Code of Federal Regulations (CFR) 300.410. The scope of the evaluation included the aboveground portions of the 108-F Biology Laboratory in the 100-F Area and all inactive ancillary buildings and structures in the 100-B/C Area, excluding the reactor building and the river outfall. Based on the evaluation, RL determined that hazardous substances in the 108-F Biology Laboratory and five of the 100-B/C Area facilities may present a potential threat to human health or the environment, and that a non-time critical removal action at these facilities is warranted. This determination was documented in an engineering evaluation/cost analysis (EE/CA) approval memorandum. The EE/CA approval memorandum is the basis on which to proceed with the performance of an EE/CA to determine the appropriate removal action. This report presents the results of the EE/CA for removal alternatives for final disposition of these six facilities. The EE/CA was conducted pursuant to the requirements of CERCLA and 40 CFR 300.415 and is intended to aid RL and the EPA in selecting a preferred removal action

  4. 39 CFR 601.108 - SDR Official disagreement resolution.

    Science.gov (United States)

    2010-07-01

    ... purchasing decisions and the administrative records concerning those decisions. All disagreements under § 601... time to lodge a disagreement lapses. (e) Disagreement decision process. The SDR Official will promptly...: INTELLECTUAL PROPERTY RIGHTS OTHER THAN PATENTS PURCHASING OF PROPERTY AND SERVICES § 601.108 SDR Official...

  5. 25 CFR 39.106 - Who is eligible for special education funding?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Who is eligible for special education funding? 39.106 Section 39.106 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION THE INDIAN SCHOOL... for special education funding? To receive ISEP special education funding, a student must be under 22...

  6. Interim safety equipment list for 241-C-106 waste retrieval, project W-320

    International Nuclear Information System (INIS)

    Conner, J.C.

    1996-01-01

    The purpose of this supporting document is to provide safety classifications for systems, structures, and components of the Tank 241-C-106 Waste Retrieval Sluicing System (WRSS) and to document the methodology used to develop these safety classifications. The WRSS requires two transfer lines, one to carry sluiced waste slurry to tank 241-AY-102 and the other to return supernatant to tank 241-C-106; pumps in each tank; sluicers to direct the supernatant stream inside tank 241-C-106; a slurry distributor in tank 241-AY-102; heating, ventilation, and air conditioning for tank 241-C-106; and instrumentation and control devices

  7. Interim safety equipment list for 241-C-106 waste retrieval, project W-320

    Energy Technology Data Exchange (ETDEWEB)

    Conner, J.C.

    1996-01-25

    The purpose of this supporting document is to provide safety classifications for systems, structures, and components of the Tank 241-C-106 Waste Retrieval Sluicing System (WRSS) and to document the methodology used to develop these safety classifications. The WRSS requires two transfer lines, one to carry sluiced waste slurry to tank 241-AY-102 and the other to return supernatant to tank 241-C-106; pumps in each tank; sluicers to direct the supernatant stream inside tank 241-C-106; a slurry distributor in tank 241-AY-102; heating, ventilation, and air conditioning for tank 241-C-106; and instrumentation and control devices.

  8. High spin states in 106In

    International Nuclear Information System (INIS)

    Deo, A.Y.; Palit, R.; Naik, Z.; Joshi, P.K.; Mazumdar, I.; Jain, H.C.; Sihotra, S.; Kumar, S.; Basu, Kausik; Chakrabarti, R.; Kshetri, R.

    2007-01-01

    Systematic study of isotopes to understand evolution of magnetic rotation bands from single particle states, with increasing neutron number, and subsequent interplay between the shears mechanism and collective rotation have not been understood properly. In the following, we present experimental work done in order to address the above aspects through the study of 106 In

  9. Mortality and repellent effects of microbial pathogens on Coptotermes formosanus (Isoptera: Rhinotermitidae

    Directory of Open Access Journals (Sweden)

    Wright Maureen S

    2012-12-01

    Full Text Available Abstract Background Two entomopathogenic fungi, Isaria fumosorosea and Metarhizium anisopliae, and one bacterium, Bacillus thuringiensis, were tested for their ability to cause mortality of Formosan subterranean termites (FST, Coptotermes formosanus (Shiraki, after liquid exposure, and for their lack of propensity to repel FST. Results The fungus Isaria fumosorosea at 108 spores/ml caused 72.5% mortality on day 7, significantly higher than the control and 106 spores/ml treatment. On day 14, the 106 and 108 concentrations caused 38.8% and 92.5% mortality, respectively, significantly higher than the control. On day 21, 82.5% and 100% of the termites were killed by the 106 and 108 treatments, respectively. I. fumosorosea did not repel termites at 106 nor 108 spores/g in sand, soil or sawdust. The fungus Metarhizium anisopliae at 108 spores/ml caused 57.5% mortality on day 7, 77.5% mortality on day 14 and 100% mortality on day 21. Conclusions On all three days the rate of mortality was significantly higher than that of the control and 106 spores/ml treatment with I. fumosorosea. Neither I. fumosorosea nor M. anisopliae caused repellency of FST in sand, soil or sawdust. The bacterium Bacillus thuringiensis did not cause significant mortality on days 7, 14 or 21. When termites were exposed to cells of B. thuringiensis in sawdust and when termites were exposed to a mixture of spores and cells in sand, a significantly higher number remained in the control tubes. Repellency was not seen with B. thuringiensis spores alone, nor with the above treatments in the other substrates.

  10. 5 CFR 3201.108 - Related statutory and regulatory authorities.

    Science.gov (United States)

    2010-01-01

    ... SUPPLEMENTAL STANDARDS OF ETHICAL CONDUCT FOR EMPLOYEES OF THE FEDERAL DEPOSIT INSURANCE CORPORATION § 3201.108... use of manipulative or deceptive devices in connection with the purchase or sale of any security. (d...

  11. 11 CFR 106.3 - Allocation of expenses between campaign and non-campaign related travel.

    Science.gov (United States)

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Allocation of expenses between campaign and non-campaign related travel. 106.3 Section 106.3 Federal Elections FEDERAL ELECTION COMMISSION GENERAL ALLOCATIONS OF CANDIDATE AND COMMITTEE ACTIVITIES § 106.3 Allocation of expenses between campaign and non...

  12. Seismic evaluation of Tank 241C106 in support of retrieval activities

    International Nuclear Information System (INIS)

    Wallace, D.A.

    1994-01-01

    Tank 241C106 (C106) is a domed, single-shell high-level waste storage tank that has been in service in the 200 East Area of the Hanford Site since 1947. Tank C106 is one of twelve tanks in a 4 x 3 array with a 100-ft center-to-center spacing. Each of the tanks is approximately 75 ft in diameter, 24-ft high at the haunch, and 33-ft high at the dome apex. The level of waste in C106 and the associated thermal environment have varied throughout the life of the tanks with the peak temperature in the concrete reaching approximately 300 F at the base of the tank in the mid-1970's (Bander 1992). The calculated peak temperature in the concrete has decreased since that time to approximately 200 F. The peak temperature occurs at the inside bottom of the tank; concrete temperatures in the wall and dome are less than 130 F. The waste inside the tank is primarily solid matter approximately 7- to 8-ft deep. The tank is completely buried in dry, sandy soil to a depth of approximately 6 ft at the dome apex. The in situ evaluation of C106 documented in July 1994 includes only the effects of gravity and thermal loads. A preliminary seismic evaluation of C106 considering only horizontal excitation demonstrated the finite-element program SASSI (A System for Analysis of Soil-Structure Interaction) and provided an estimate of seismic effects including soil-to-structure interaction. This final seismic evaluation expands on the preliminary seismic evaluation to include further verification and refinement of analysis parameters, quantification to tank-to-tank and waste-to-tank interaction, and examination of the effects of vertical seismic excitation. The concrete structure of tank C106 is classified as a Safety Class 1 non-reactor structure

  13. 41 CFR 101-39.106 - Unlimited exemptions.

    Science.gov (United States)

    2010-07-01

    ...-INTERAGENCY FLEET MANAGEMENT SYSTEMS 39.1-Establishment, Modification, and Discontinuance of Interagency Fleet Management Systems § 101-39.106 Unlimited exemptions. Unlimited exemptions from inclusion in the fleet... below. Unlimited exemptions do not preclude agencies from requesting fleet management services, if...

  14. Shortcomings of the industrial quality assurance of 106Ru ophthalmic plaques

    International Nuclear Information System (INIS)

    Kaulich, T.W.; Nuesslin, F.; Fluehs, D.; Haug, T.; Bamberg, M.

    2001-01-01

    Background: Beta emitting 106 Ru applicators manufactured by Bebig GmbH (Berlin, Germany) are widely used to treat intraocular tumors. The applicators are fixed to the bulbus and removed after several days. The following therapy relevant defects have been detected by an internal clinical acceptance test: risk of leakage and inconsistent dose-rate specifications by the manufacturer. In the meantime, components of the internal clinical acceptance test have been adopted successfully by the manufacturer of the 106 Ru ophthalmic plaques. Material and Method: 106 Ru ophthalmic plaques were tested with the following internal clinical acceptance tests: visual inspection, surface contamination, leakage, and dose-rate verification. The surface contamination test consists of a wet wipe test at moderate pressure. For the leakage test of the 106 Ru ophthalmic plaques a clinically relevant scenario was developed in which the contact of the applicator with human tissue is simulated. In the course of it the applicator is inserted into Ringer's solution for several days. The certified energy dose-rate statements of the manufacturer are examined with a 1 mm 3 plastic scintillator for consistency. (orig.) [de

  15. Partition of ruthenium-106 between the fresh water environment and crayfish

    International Nuclear Information System (INIS)

    Berg, G.G.; Ginsberg, E.

    1976-01-01

    Crayfish of two species, Orconectes obscurus and Cambarus robustus, were identified in West Valley, New York, in streams contaminated with radioactive wastes. 106 Ru accounted for over 90% of the gamma radioactivity in specimens collected in 1972, and had higher concentrations in the crayfish than in fish from that site. Crayfish are suggested as indicator organisms for 106 Ru. In subsequent aquarium experiments, crayfish exposed to water labeled with inorganic complexes of 106 Ru concentrated the dissolved ruthenium an average of 9 x and accumulated 50% of the equilibrium body burden in approximately 10 hr, with the bulk of the isotope bound at the surface of the exoskeleton. If food was also exposed to the labeled water, uptake was faster and high concentrations were found in the digestive gland, which showed concentration factors in excess of 25 x. Releases were slower and bimodal, with approximately 10% of body burden remaining after 1 or 2 months in repeated changes of water. Data describe the partition of 106 Ru to colloidal aggregates and organically-bound sediments, and its availability for bioconcentration. (author)

  16. Tank 241-BY-108 tank characterization plan

    International Nuclear Information System (INIS)

    Carpenter, B.C.

    1994-01-01

    The sampling and analytical needs associated with the 51 Hanford Site underground storage tanks classified on one or more of the four Watch Lists (ferrocyanide, organic, flammable gas, and high heat), and the safety screening of all 177 tanks have been identified through the Data Quality Objective (DQO) process. DQOs identity information needed by a program group in the Tank Waste Remediation System concerned with safety issues, regulatory requirements, or the transporting and processing of tank waste. This Tank Characterization Plan will identify characterization objectives for tank BY-108 pertaining to sample collection, sample preparation and analysis, and laboratory analytical evaluation and reporting requirements. In addition, an estimate of the current contents and status of the tank is given. Single-shell tank BY-108 is classified as a Ferrocyanide Watch List tank. The tank was declared an assumed leaker and removed from service in 1972; interim stabilized was completed in February 1985. Although not officially an Organic Watch List tank, restrictions have been placed on intrusive operations by Standing Order number-sign 94-16 (dated 09/08/94) since the tank is suspected to contain or to have contained a floating organic layer

  17. Direct flow in 10.8 GeV/nucleon Au+Au collisions measured in experiment E917 at the AGS

    International Nuclear Information System (INIS)

    Back, B. B.; Betts, R. R.; Britt, H. C.; Chang, J.; Chang, W. C.; Gillitzer, A.; Henning, W. F.; Hofman, D. J.; Nanal, V.; Wuosmaa, A. H.

    1999-01-01

    Analysis of directed flow observable for protons and pions from Au+Au collisions at 10.8 GeV/nucleon from experiment E917 at the AGS is presented. Using a Fourier series expansion, the first Fourier component, ν 1 ,was extracted as a function of rapidity for mid-central collisions (17-24%). Clear evidence for positive directed flow is found in the proton data, and a weak, possibly negative directed flow signal is observed for π + and π -

  18. 20 CFR 653.108 - State agency self-monitoring.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false State agency self-monitoring. 653.108 Section... agency self-monitoring. (a) State Administrators shall assure that their State agencies monitor their own... overall responsibility for State agency self-monitoring. (b) The State Administrator shall appoint a State...

  19. Rapid determination of phenolic compounds in water samples by alternating-current oscillopolarographic titration

    Institute of Scientific and Technical Information of China (English)

    XIAO Jun-ping; WANG Xue-feng; ZHOU Qing-xiang; FAN Xiao-yuan; SU Xian-fa; Bai Hua-hua; DUAN Hai-jing

    2007-01-01

    A rapid, simple and sensitive method was demonstrated for the determination of phenolic compounds in water samples by alternating-current oscillopolarographic titration. With the presence of sulfuric acid, phenol could be transferred into a nitroso-compound by reacting with NaNO2. The titration end-point was obtained by the formation of a sharp cut in the oscillopolarographic with infinitesimal NaNO2 on double platinum electrodes. The results showed that phenol had an excellent linear relationship over the range of 4.82×10-6 -9.65×10-3 mol/L, the RSD of the proposed method was lower than 1.5%, and the spiked recoveries of three real water samples were in the range of 95.6%-106.9%.

  20. 17 CFR 256.108 - Accumulated provision for depreciation and amortization of service company property.

    Science.gov (United States)

    2010-04-01

    ..., unless the company maintains costs and related reserves for specific units or types of property. (c... depreciation and amortization of service company property. 256.108 Section 256.108 Commodity and Securities... COMPANIES AND SUBSIDIARY SERVICE COMPANIES, PUBLIC UTILITY HOLDING COMPANY ACT OF 1935 Balance Sheet...

  1. 77 FR 27451 - Boott Hydropower, Inc.; Notice of Section 106 Consultation Meeting

    Science.gov (United States)

    2012-05-10

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 2790-055] Boott Hydropower, Inc.; Notice of Section 106 Consultation Meeting On May 24, 2012, Federal Energy Regulatory Commission... Historic Preservation, Boott Hydropower, Inc., and any other consulting parties for the section 106 process...

  2. Studies on transfer and accumulation of 106Ru from seaweed to fish through crustacea, 2

    International Nuclear Information System (INIS)

    Izumo, Yoshiro

    1982-01-01

    This paper deals with transfer and accumulation of 106 Ru in a model of the graizing food chain of marine organisms: the radioactive sea water → seaweed (Chondrus crispus) → crustacea (prawn, Palaemon serratus) → fish (plaice, Pleuronectes platessa). The seaweeds were cultured in the radioactive sea waters A (filtrated and circulated through sandy mud, the radioactive concentration decreased and atteined to constant after addition of 106 Ru), B (not filtrated and circulated, the radioactive concentration decreased and atteined to constant) and C (not filtrated and circulated, the radioactive concentration decreased, but did not attein to constant), respectively, and investigated accumulations of 106 Ru. Thereafter, accumulations of 106 Ru in prawns and plaice by the ingestions of their diets (the seaweeds contaminated with 106 Ru in each water and the meats of prawns accumulated 106 Ru from each diet, respectively), were investigated and compared with those from the radioactive sea waters reported previously. It was shown that 106 Ru would be accumulated by the prawns from the sea water A about 3 times higher than from the contaminated diet in this water, however from the contaminated diets in the waters B and C about 2 times, respectively, higher than from each water. While, accumulations of 106 Ru by the plaice from each diet were negligible in comparison with those from each water. No higher concentrations of 106 Ru were observed in these organisms from lower to higher in the trophic level. (author)

  3. miR-106a suppresses tumor cells death in colorectal cancer through targeting ATG7.

    Science.gov (United States)

    Hao, Haibin; Xia, Guangfeng; Wang, Chao; Zhong, Fuping; Liu, Laipeng; Zhang, Dong

    2017-06-01

    Autophagy-related gene 7 (ATG7) and miR-106a play an important role in cancer cell autophagy and apoptosis, but the outcome of ATG7 and miR-106a in colorectal cancer (CRC) still remains not clear. In this study, we found that ATG7 and miR-106a expression were mutually related with cell death and prognosis in CRC patients. In addition, we also showed that ATG7 and miR-106a expression were changeable in colorectal cancer cell lines when compared with normal cell lines, but ATG7 and miR-106a mRNA level was negatively correlated. Furthermore, ATG7 protein and mRNA levels decreased after over-expression of miR-106a, whereas the suppression of ATG7 had the opposite effect. We confirmed that miR-106a down-regulated ATG7 mRNA level by binding the specific sequence of ATG7 mRNA 3'UTR region. Moreover, the over-expression of ATG7 induced CRC cells death both in vitro and in vivo. Taken together, our study data demonstrated that ATG7 aggravated the cell death of CRC, which was inhibited by miR-106a.

  4. 46 CFR 108.437 - Pipe sizes and discharge rates for enclosed ventilation systems for rotating electrical equipment.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Pipe sizes and discharge rates for enclosed ventilation systems for rotating electrical equipment. 108.437 Section 108.437 Shipping COAST GUARD, DEPARTMENT OF... Systems Fixed Carbon Dioxide Fire Extinguishing Systems § 108.437 Pipe sizes and discharge rates for...

  5. Potential Environmental Benefits from Increased Use of Bioenergy in China

    Science.gov (United States)

    Fan, Shuyang; Freedman, Bill; Gao, Jixi

    2007-09-01

    Because of its large population and rapidly growing economy, China is confronting a serious energy shortage and daunting environmental problems. An increased use of fuels derived from biomass could relieve some demand for nonrenewable sources of energy while providing environmental benefits in terms of cleaner air and reduced emissions of greenhouse gases. In 2003, China generated about 25.9 × 108 metric tons of industrial waste (liquid + solid), 14.7 × 108 metric tons/year (t/y) of manure (livestock + human), 7.1 × 108 t/y of crop residues and food-processing byproducts, 2 × 108 t/y of fuelwood and wood manufacturing residues, and 1.5 × 108 t/y of municipal waste. Biofuels derived from these materials could potentially displace the use of about 4.12 × 108 t/y of coal and 3.75 × 106 t/y of petroleum. An increased bioenergy use of this magnitude would help to reduce the emissions of key air pollutants: SO2 by 11.6 × 106 t/y, NOX by 1.48 × 106 t/y, CO2 by 1.07 × 109 t/y, and CH4 by 50 × 106 t/y. The reduced SO2 emissions would be equivalent to 54% of the national emissions in 2003, whereas those for CO2 are 30%. It is important to recognize, however, that large increases in the use of biomass fuels also could result in socioeconomic and environmental problems such as less production of food and damage caused to natural habitats.

  6. Medicinal plants as alternative treatments for female sexual dysfunction: utopian vision or possible treatment in climacteric women?

    Science.gov (United States)

    Mazaro-Costa, Renata; Andersen, Monica L; Hachul, Helena; Tufik, Sergio

    2010-11-01

    Female sexual dysfunction (FSD) is a complex and multifactorial condition. An increased incidence of FSD is especially associated with the decline of estrogen. Thus, menopause is a critical phase for FSD complaints. In this context, medicinal plants may be a therapeutic option. To identify and describe the popular and clinical uses of medicinal plants for FSD treatment in climacteric women. We highlighted the majority of the plants commonly involved with the female reproductive system including: Angelica sinensis, Cimicifuga racemosa, Ferula hermonis, Ginkgo biloba, Humulus lupulus, Lepidium meyenii, Tribulus terrestris, Trifolium pratense, and Vitex agnus-castus. This study is a narrative review of studies of plants that are possible alternative treatments for FSD. The species described have clinical and popular uses in different cultures as well as medical indications for female reproductive disturbances, mainly in climacteric women. We have also analyzed the evidence level of clinical studies. The main outcome assessed is the efficacy of plants in improving the symptoms of FSD. There is little evidence from the literature to recommend the use of medicinal plants when treating FSD. The majority of studies with a strong level of evidence are associated with the treatment of the vasomotor symptoms of menopause. Ferula hermonis, Angelica sinensis, and Gingko biloba may be suggested for arousal disorder studies. Cimicifuga racemosa, Trifolium pratense, and Vitex agnus-castus may be recommended for several FSD. Humulus lupulus and Tribulus terrestris may help with desire disorder studies. Lepidium meyenii should be studied further. Studies of these plants indicate that they may be useful as a possible alternative and/or complementary approach for studies aimed at the treatment of FSD. At this time, however, this review cannot recommend a plant that has a strong enough level of evidence for treatment of FSD. Thus, there is a need for clinical (double-blinded and

  7. 24 CFR 811.106 - Default under the contract.

    Science.gov (United States)

    2010-04-01

    ... AND URBAN DEVELOPMENT (SECTION 8 HOUSING ASSISTANCE PROGRAMS, SECTION 202 DIRECT LOAN PROGRAM, SECTION... DISABILITIES PROGRAM) TAX EXEMPTION OF OBLIGATIONS OF PUBLIC HOUSING AGENCIES AND RELATED AMENDMENTS § 811.106...

  8. 48 CFR 828.106-72 - Contract provision.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract provision. 828... GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Bonds and Other Financial Protections 828.106-72 Contract provision. Insert 852.228-72, Assisting Service-Disabled Veteran-Owned and Veteran-Owned Small...

  9. Selective Leaching of Chromium from Hanford Tank Sludge 241-U-108

    International Nuclear Information System (INIS)

    Rapko, Brian M.; Vienna, John D.

    2002-01-01

    This study evaluated the oxidants permanganate, MnO4-, and peroxynitrite, ONOO-, as selective chromium-leaching agents from washed 241-U-108 tank sludge under varying conditions of hydroxide concentration, temperature, and time. The mass changes and final sludge compositions were evaluated using glass-property models to ascertain the relative impacts of the various oxidative alkaline leach conditions on the amount of borosilicate glass required to immobilize a given amount of washed 241-U-108 Hanford tank sludge. Only permanganate leaching removes sufficient chromium to make the chromium concentration in the oxidatively alkaline leached solids non-limiting. In the absence of added oxidants, continued washing or caustic leaching have no beneficial effects. Peroxynitrite addition reduces the amount of glass required to immobilize a given amount of washed 241-U-108 tank sludge by approximately a factor of two. Depending on the leach conditions and the exact chromium concentration limits, contact with alkaline permanganate solutions reduces the amount of immobilized high-level waste glass by a factor of 10 to 30

  10. Selective Leaching of Chromium from Hanford Tank Sludge 241-U-108

    Energy Technology Data Exchange (ETDEWEB)

    Rapko, Brian M.; Vienna, John D.

    2002-09-09

    This study evaluated the oxidants permanganate, MnO4-, and peroxynitrite, ONOO-, as selective chromium-leaching agents from washed 241-U-108 tank sludge under varying conditions of hydroxide concentration, temperature, and time. The mass changes and final sludge compositions were evaluated using glass-property models to ascertain the relative impacts of the various oxidative alkaline leach conditions on the amount of borosilicate glass required to immobilize a given amount of washed 241-U-108 Hanford tank sludge. Only permanganate leaching removes sufficient chromium to make the chromium concentration in the oxidatively alkaline leached solids non-limiting. In the absence of added oxidants, continued washing or caustic leaching have no beneficial effects. Peroxynitrite addition reduces the amount of glass required to immobilize a given amount of washed 241-U-108 tank sludge by approximately a factor of two. Depending on the leach conditions and the exact chromium concentration limits, contact with alkaline permanganate solutions reduces the amount of immobilized high-level waste glass by a factor of 10 to 30.

  11. Measurement of the quadrupole moments of the strongly deformed nuclei 18173Ta108 and 18375Re108 by hyperfine interaction in metals

    International Nuclear Information System (INIS)

    Netz, G.

    1974-01-01

    The quadrupole moments of two single particle proton states were measured in the strongly deformed nuclei region. Both measurements are independent of model because the field gradient is known in a rhenium lattice as well as at the nucleus site of a rhenium atom and also at the nucleus site of an incorporated tantalum atom. The quadrupole moments could thus be directly extracted from the quadrupole interaction frequency, the product of quadrupole moment and field gradient. For the 482 keV state (I = 5/2 + ) in 181 73 Ta 108 one obtains a quadrupole moment of: Q (5/2) = 2.5 +- 0.2 barn. For the 496 keV state (I = 9/2 - ) in 183 75 Re 108 , a quadrupole moment of: Q (0/2) = 3.6 +- 0.4 barn is found. This value agrees well with other experimental data within the framework of the collective model. (orig./LH) [de

  12. Data Management-Supplement to Section 106 Tribal Guidance

    Science.gov (United States)

    The document supplements the Tribal 106 Guidance by providing useful suggestions and tips to tribes about how to establish a data management system that reflects tribal water quality goals and objectives.

  13. Excitation functions and isomeric ratios for the isomeric pair sup(106m)Ag and sup(106g)Ag in the 107Ag (d,t) reaction

    International Nuclear Information System (INIS)

    Lalli, M.E.; Wasilevsky de Lammirato, C.; Herreros, O.R.; Nassiff, S.J.

    1976-09-01

    Excitation functions and isomeric cross section ratios have been measured for the 107 Ag (d,t), reaction in which the isomeric pair sup(106m/106g)Ag is produced. Thick-target yields have been determined for different irradiation times and as a function of deuteron energy. Stacked silver foils with aluminium foils as monitors were bombarded with deuterons up to 27 MeV and the activities of products measured with a calibrated Ge(Li) counter. (author) [es

  14. 41 CFR 109-39.106 - Unlimited exemptions.

    Science.gov (United States)

    2010-07-01

    ..., AND MOTOR VEHICLES 39-INTERAGENCY FLEET MANAGEMENT SYSTEMS 39.1-Establishment, Modification, and Discontinuance of Interagency Fleet Management Systems § 109-39.106 Unlimited exemptions. The Director, Office of... determination that an unlimited exemption from inclusion of a motor vehicle in a fleet management system is...

  15. Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design.

    Science.gov (United States)

    Bjelic, Sinisa; Kipnis, Yakov; Wang, Ling; Pianowski, Zbigniew; Vorobiev, Sergey; Su, Min; Seetharaman, Jayaraman; Xiao, Rong; Kornhaber, Gregory; Hunt, John F; Tong, Liang; Hilvert, Donald; Baker, David

    2014-01-09

    Designed retroaldolases have utilized a nucleophilic lysine to promote carbon-carbon bond cleavage of β-hydroxy-ketones via a covalent Schiff base intermediate. Previous computational designs have incorporated a water molecule to facilitate formation and breakdown of the carbinolamine intermediate to give the Schiff base and to function as a general acid/base. Here we investigate an alternative active-site design in which the catalytic water molecule was replaced by the side chain of a glutamic acid. Five out of seven designs expressed solubly and exhibited catalytic efficiencies similar to previously designed retroaldolases for the conversion of 4-hydroxy-4-(6-methoxy-2-naphthyl)-2-butanone to 6-methoxy-2-naphthaldehyde and acetone. After one round of site-directed saturation mutagenesis, improved variants of the two best designs, RA114 and RA117, exhibited among the highest kcat (>10(-3)s(-1)) and kcat/KM (11-25M(-1)s(-1)) values observed for retroaldolase designs prior to comprehensive directed evolution. In both cases, the >10(5)-fold rate accelerations that were achieved are within 1-3 orders of magnitude of the rate enhancements reported for the best catalysts for related reactions, including catalytic antibodies (kcat/kuncat=10(6) to 10(8)) and an extensively evolved computational design (kcat/kuncat>10(7)). The catalytic sites, revealed by X-ray structures of optimized versions of the two active designs, are in close agreement with the design models except for the catalytic lysine in RA114. We further improved the variants by computational remodeling of the loops and yeast display selection for reactivity of the catalytic lysine with a diketone probe, obtaining an additional order of magnitude enhancement in activity with both approaches. © 2013.

  16. 21 CFR 108.12 - Manufacturing, processing, or packing without a permit, or in violation of a permit.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Manufacturing, processing, or packing without a permit, or in violation of a permit. 108.12 Section 108.12 Food and Drugs FOOD AND DRUG ADMINISTRATION... General Provisions § 108.12 Manufacturing, processing, or packing without a permit, or in violation of a...

  17. Acceptance test report for the Tank 241-C-106 in-tank imaging system

    International Nuclear Information System (INIS)

    Pedersen, L.T.

    1998-01-01

    This document presents the results of Acceptance Testing of the 241-C-106 in-tank video camera imaging system. The purpose of this imaging system is to monitor the Project W-320 sluicing of Tank 241-C-106. The objective of acceptance testing of the 241-C-106 video camera system was to verify that all equipment and components function in accordance with procurement specification requirements and original equipment manufacturer's (OEM) specifications. This document reports the results of the testing

  18. 46 CFR 108.409 - Location and spacing of tubing in pneumatic fire detection system.

    Science.gov (United States)

    2010-10-01

    ... detection system. 108.409 Section 108.409 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... and spacing of tubing in pneumatic fire detection system. (a) All tubing in a pneumatic fire detection... exposed in the space. (c) A pneumatic fire detection system must be set to activate after approximately a...

  19. High-Temperature Lead-Free Solder Alternatives: Possibilities and Properties

    DEFF Research Database (Denmark)

    High-temperature solders have been widely used as joining materials to provide stable interconnections that resist a severe thermal environment and also to facilitate the drive for miniaturization. High-lead containing solders have been commonly used as high-temperature solders. The development...... of high-temperature lead-free solders has become an important issue for both the electronics and automobile industries because of the health and environmental concerns associated with lead usage. Unfortunately, limited choices are available as high-temperature lead-free solders. This work outlines...... the criteria for the evaluation of a new high-temperature lead-free solder material. A list of potential ternary high-temperature lead-free solder alternatives based on the Au-Sn and Au-Ge systems is proposed. Furthermore, a comprehensive comparison of the high-temperature stability of microstructures...

  20. Nuclear-physical properties of 105,106m,110mAg

    International Nuclear Information System (INIS)

    Popov, Yu. S.; Zakharova, L. V.; Sadulin, V. V.; Andreev, O. I.; Pakhomov, A. N.

    2005-01-01

    The nuclear-physical properties of the nuclides 105,106m,110m Ag, which are concomitant nuclides in reactor production of 103 Pd and 109 Cd used in metrology of ionizing radiations and in nuclear medicine, were studied. The following quantities were determined by semiconductor X-ray and γ-ray spectrometry: the parameter K α /K β of X-ray K radiation accompanying the decay of 110m Ag and the intensities of γ-ray quanta with the energies of 280 and 345 keV ( 105 Ag); 430, 451, and 512 keV ( 106m Ag); 658, 764, 885, 938, and 1384 keV ( 110m Ag). The half-lives determined using the above γ-ray lines are as follows: T 1/2 ( 105 Ag) = 41.2 ± 0.1 days; T 1/2 ( 106m Ag) = 8.30 ± 0.07 days. The errors are given for 95% confidence level [ru

  1. Barriers and possibilities for the emerging alternative lighting technologies

    DEFF Research Database (Denmark)

    Bjarklev, Araceli; Kjær, Tyge; Andersen, Jan

    2009-01-01

    the incandescent lamp; However, the emergence of other illumination technologies such as Light Emitting Diodes (LEDs) are currently raising in question, whether the fluorescent lamp is the technology that best can reduce the (large) illumination cological footprint. Europe and more specifically Denmark, a country......20% of the total electricity produced in the world today is used for illumination. Though the use of energy in Europe almost stagnated during the 1990ies, studies reveal that for the next 30 years the consumption of electricity will again increase making the 20% reduction of CO2 goal almost...... are the main possibilities and limitations for the Danish lighting Industry to help reducing the global illumination ecological footprint and what can be improved in the current illumination value chain in order to use the possibilities?...

  2. Tank 241-BY-106 tank characterization plan

    International Nuclear Information System (INIS)

    Schreiber, R.D.

    1995-01-01

    This document is a plan which serves as the contractual agreement between the Characterization Program, Sampling Operations, PNL 325 Analytical Chemistry Laboratory, and WHC 222-S Laboratory. The scope of this plan is to provide guidance for the sampling and analysis of samples for tank 241-BY-106

  3. 10 CFR 2.106 - Notice of issuance.

    Science.gov (United States)

    2010-01-01

    ... previously published. (d) The Director of Nuclear Material Safety and Safeguards will also cause to be... Application-How Initiated § 2.106 Notice of issuance. (a) The Director, Office of New Reactors, Director, Office of Nuclear Reactor Regulation, or Director, Office of Nuclear Material Safety and Safeguards, as...

  4. Alternative methods for measuring obesity in African American women.

    Science.gov (United States)

    Clark, Ashley E; Taylor, Jacquelyn Y; Wu, Chun Yi; Smith, Jennifer A

    2013-03-01

    The use of body mass index (BMI) may not be the most appropriate measurement tool in determining obesity in diverse populations. We studied a convenience sample of 108 African American (AA) women to determine the best method for measuring obesity in this at-risk population. The purpose of this study was to determine if percent body fat (PBF) and percent body water (PBW) could be used as alternatives to BMI in predicting obesity and risk for hypertension (HTN) among AA women. After accounting for age, BMI, and the use of anti-hypertensive medication, PBF (p = 0.0125) and PBW (p = 0.0297) were significantly associated with systolic blood pressure, while BMI was not. Likewise, PBF (p = 0.0316) was significantly associated with diastolic blood pressure, while PBW and BMI were not. Thus, health care practitioners should consider alternative anthropometric measurements such as PBF when assessing obesity in AA women.

  5. Use of alternative product in patients with chronic viral hepatitis

    Directory of Open Access Journals (Sweden)

    Mahmut Dulger

    2014-09-01

    Full Text Available Objectives: Some of the patients with chronic hepatitis use both alternative product and/or antiviral treatment. These herbal products sometimes lead to clinical deterioration. In this study we aimed to determine the purpose of alternative product utilization and rate among the chronic hepatitis B (CHB and C (CHC patients. Methods: This prospective cohort study included 200 consecutive adult patients with chronic hepatitis B and C at the Department of Infectious Diseases, Ondokuz Mayis University, between 1 March 2012 and 30 July 2012. At enrollment, clinical information, demographics, laboratory variables and knowledge about alternative products were recorded. Results: Of the patients 150 had CHB, 50 had CHC. 54% of patients were male. Use of alternative products was 26%. Antiviral treatment rate was 48.5% for all patients. The most used alternative products were artichoke extract and honey. 67.3% of patients were using single alternative product whereas the others were using two or more alternative products. 46.2% of patients who use alternative product provided information about the alternative product usage, but the others did not. Conclusions: Majority of patients used alternative products. More than half of these patients did not give information to their physicians about their use of alternative medicine. Use of alternative product should be asked in all patients with chronic hepatitis. Herbal product usage was detected in majority of patients and also approximately half of these patients did not give information to their doctors about taking alternative medicine. In conclusion, it is necessary to take detailed information about herbal product usage in patients with chronic hepatitis. J Microbiol Infect Dis 2014; 4(3: 102-106

  6. 48 CFR 2913.106-3 - Soliciting competition, evaluation of quotations or offers, award and documentation.

    Science.gov (United States)

    2010-10-01

    ..., evaluation of quotations or offers, award and documentation. 2913.106-3 Section 2913.106-3 Federal... Procedures 2913.106-3 Soliciting competition, evaluation of quotations or offers, award and documentation. In... responsive quotation from a responsible supplier is used as the basis for a purchase, the contracting officer...

  7. 48 CFR 37.108 - Small business Certificate of Competency.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Small business Certificate... proposal and a resultant technical evaluation and source selection, the small business Certificate of... REGULATION SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Service Contracts-General 37.108 Small...

  8. 18 CFR 1300.106 - Harassment on the basis of race, color, religion, age, or disability.

    Science.gov (United States)

    2010-04-01

    ... of race, color, religion, age, or disability. 1300.106 Section 1300.106 Conservation of Power and... AUTHORITY § 1300.106 Harassment on the basis of race, color, religion, age, or disability. It is TVA policy... basis of race, color, religion, age, or disability. Accordingly, all employees must avoid any action or...

  9. 21 CFR 106.30 - Finished product evaluation.

    Science.gov (United States)

    2010-04-01

    ... degradation; and (ii) All nutrients not previously analyzed for by the manufacturers, unless each in-process... specified in § 106.20(b). No analyses are needed for linoleic acid, vitamin D, vitamin K, choline, inositol... maintenance of nutrient content throughout the shelf life of the product. (c) The manufacturer shall evaluate...

  10. ELECTROCHEMICAL CORROSION TESTING OF TANKS 241-AN-102 & 241-AP-107 & 241-AP-108 IN SUPPORT OF ULTRASONIC TESTING

    Energy Technology Data Exchange (ETDEWEB)

    WYRWAS RB; DUNCAN JB

    2008-11-20

    This report presents the results of the corrosion rates that were measured using electrochemical methods for tanks 241-AN-102 (AN-102), 241-AP-107 (AP 107), and 241-AP-108 (AP-108) performed under test plant RPP-PLAN-38215. The steel used as materials of construction for AN and AP tank farms was A537 Class 1. Test coupons of A537 Class 1 carbon steel were used for corrosion testing in the AN-107, AP-107, and AP-108 tank waste. Supernate will be tested from AN-102, AP-107, and Ap-108. Saltcake testing was performed on AP-108 only.

  11. Elevated TMEM106B levels exaggerate lipofuscin accumulation and lysosomal dysfunction in aged mice with progranulin deficiency.

    Science.gov (United States)

    Zhou, Xiaolai; Sun, Lirong; Brady, Owen Adam; Murphy, Kira A; Hu, Fenghua

    2017-01-26

    Mutations resulting in haploinsufficiency of progranulin (PGRN) cause frontotemporal lobar degeneration with TDP-43-positive inclusions (FTLD-TDP), a devastating neurodegenerative disease. Accumulating evidence suggest a crucial role of progranulin in maintaining proper lysosomal function during aging. TMEM106B has been identified as a risk factor for frontotemporal lobar degeneration with progranulin mutations and elevated mRNA and protein levels of TMEM106B are associated with increased risk for frontotemporal lobar degeneration. Increased levels of TMEM106B alter lysosomal morphology and interfere with lysosomal degradation. However, how progranulin and TMEM106B interact to regulate lysosomal function and frontotemporal lobar degeneration (FTLD) disease progression is still unclear. Here we report that progranulin deficiency leads to increased TMEM106B protein levels in the mouse cortex with aging. To mimic elevated levels of TMEM106B in frontotemporal lobar degeneration (FTLD) cases, we generated transgenic mice expressing TMEM106B under the neuronal specific promoter, CamKII. Surprisingly, we found that the total protein levels of TMEM106B are not altered despite the expression of the TMEM106B transgene at mRNA and protein levels, suggesting a tight regulation of TMEM106B protein levels in the mouse brain. However, progranulin deficiency results in accumulation of TMEM106B protein from the transgene expression during aging, which is accompanied by exaggerated lysosomal abnormalities and increased lipofuscin accumulation. In summary, our mouse model nicely recapitulates the interaction between progranulin and TMEM106B in human patients and supports a critical role of lysosomal dysfunction in the frontotemporal lobar degeneration (FTLD) disease progression.

  12. 13 CFR 108.691 - Responsibilities of NMVC Company during examination.

    Science.gov (United States)

    2010-01-01

    ... § 108.620(c). In addition, the agreement between you and the independent public accountant performing your audit must provide that any information in the accountant's working papers be made available to...

  13. Thermal stability of the DSC ruthenium dye C106 in robust electrolytes

    DEFF Research Database (Denmark)

    Lund, Torben; Phuong, Nguyen Tuyet; Pechy, Peter

    2014-01-01

    We have investigated the thermal stability of the heteroleptic ruthenium complex C106 employed as a sensitizer in dye-sensitized solar cells. The C106 was adsorbed on TiO2 particles and exposed to 2 different iodide/triidode based redox electrolytes A and B at 80 °C for up to 1500 h in sealed glass......) substitution products 3 and 4 formed by replacement of the thiocyanate ligand by NBB after 1500 h of heating at 80 °C. Samples prepared under ambient conditions gave a steady state C106 concentration of 60% of the initial value and 40% substitution products. The C106 degradation was found to be independent...... of the degree of dye loading of the TiO2 particles and the ratio between the amount of dyed TiO2 particles and electrolyte volume. Assuming that this substitution is the predominant loss mechanism in a DSC during thermal stress, we estimate the reduction in the DSC efficiency after long term heat to be 12...

  14. Improvement in solvent tolerance by exogenous glycerol in Pseudomonas sp. BCNU 106.

    Science.gov (United States)

    Choi, H J; Lim, B R; Park, Y J; Joo, W H

    2017-08-01

    Solvent hypertolerant Pseudomonas sp. BCNU 106 still has some underlying growth limitation in solvents. Therefore, efficient mass cultivation methods are needed to pursue its applications in biotechnology. Pseudomonas sp. BCNU 106 was cultured in a medium supplemented with 0·05 mol l -1 glycerol and cell survival was monitored during its cultivation in the presence of 1% (v/v) toluene. Exogenously supplemented glycerol provided more protection against damage caused by toluene stress and conferred higher solvent tolerance of Pseudomonas sp. BCNU 106 to toluene compared to control Pseudomonas sp. BCNU 106 without the supplementation of glycerol. This low-cost mass cultivation method can be used to efficiently apply solvent-tolerant bacteria in biotransformation and biodegradation. Protection against toluene and improvement in bacterial cell growth by supplementation of glycerol in the presence of toluene are demonstrated in this study. This result can be used to solve growth-related hindrances of solvent-tolerant bacteria and establish their low-cost mass cultivation, thereby broadening their industrial and environmental applications. © 2017 The Society for Applied Microbiology.

  15. 29 CFR 825.106 - Joint employer coverage.

    Science.gov (United States)

    2010-07-01

    ... facts and circumstances. A PEO does not enter into a joint employment relationship with the employees of... Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS THE FAMILY AND MEDICAL LEAVE ACT OF 1993 Coverage Under the Family and Medical Leave Act § 825.106 Joint employer...

  16. 25 CFR 115.106 - Assets of members of the Agua Caliente Band of Mission Indians.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Assets of members of the Agua Caliente Band of Mission Indians. 115.106 Section 115.106 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR FINANCIAL ACTIVITIES TRUST FUNDS FOR TRIBES AND INDIVIDUAL INDIANS IIM Accounts § 115.106 Assets of members of the Agua...

  17. NEW MASER EMISSION FROM NONMETASTABLE AMMONIA IN NGC 7538. III. DETECTION OF THE (10,6) TRANSITION AND A VELOCITY GRADIENT

    Energy Technology Data Exchange (ETDEWEB)

    Hoffman, Ian M., E-mail: ihoffman@wittenberg.edu [Physics Department Wittenberg University, Springfield, OH 45501 (United States)

    2012-11-01

    We present the first astronomical detection of the {sup 14}NH{sub 3} (J, K) = (10, 6) line: nonthermal emission at several velocities in the Galactic star-forming region NGC 7538. Using the Very Large Array we have imaged the (10,6) and (9,6) ammonia masers at several positions within NGC 7538 IRS 1. The individual sources have angular sizes {approx}< 0.1 arcsec corresponding to brightness temperatures T{sub B} {approx}> 10{sup 6} K. We apply the pumping model of Brown and Cragg, confirming the conjecture that multiple ortho-ammonia masers can occur with the same value of K. The positions and velocities of the (10,6) and (9,6) masers are modeled as motion in a possible disk or torus and are discussed in the context of recent models of the region.

  18. 29 CFR 570.106 - “Ship or deliver for shipment in commerce”.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false âShip or deliver for shipment in commerceâ. 570.106 Section 570.106 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS CHILD LABOR REGULATIONS, ORDERS AND STATEMENTS OF INTERPRETATION General Statements of Interpretation of the Child Labor Provisions of...

  19. Ruprecht 106 - A young metal-poor Galactic globular cluster

    International Nuclear Information System (INIS)

    Buonanno, R.; Buscema, G.; Fusi Pecci, F.; Richer, H.B.; Fahlman, G.G.

    1990-01-01

    The first CCD photometric survey in the Galactic globular cluster Ruprecht 106 has been performed. The results show that Ruprecht 106 is a metal-poor cluster with (Fe/H) about -2 located at about 25 kpc from the Galactic center. A sizable, high centrally concentrated population of blue stragglers was detected. Significant differences in the positions of the turnoffs in the color-magnitude diagram are found compared to those in metal-poor clusters. The cluster appears younger than other typical metal-poor Galactic globulars by about 4-5 Gyr; if true, this object would represent the first direct proof of the existence of a significant age spread among old, very metal-poor clusters. 51 refs

  20. 76 FR 20593 - Guidance Under Section 108(a) Concerning the Exclusion of Section 61(a)(12) Discharge of...

    Science.gov (United States)

    2011-04-13

    ... ultimate owner(s) of such partner. Some taxpayers have taken the position that the insolvency exception is... for partnerships under section 108(d)(6), the insolvency exception is available only to the extent the.... Section 1.108-9 is added to read as follows: Sec. 1.108-9 Application of insolvency and bankruptcy...

  1. 13 CFR 108.150 - Management and ownership diversity requirement.

    Science.gov (United States)

    2010-01-01

    ... VENTURE CAPITAL (âNMVCâ) PROGRAM Qualifications for the NMVC Program Organizing A Nmvc Company § 108.150... 70 percent of your Regulatory Capital or your Leverageable Capital. (c) Non-affiliation requirement. At least 30 percent of your Regulatory Capital and Leverageable Capital must be owned and controlled...

  2. Development of grout formulations for 106-AN waste: Mixture-experiment results and analysis

    International Nuclear Information System (INIS)

    Spence, R.D.; McDaniel, E.W.; Anderson, C.M.; Lokken, R.O.; Piepel, G.F.

    1993-09-01

    Twenty potential ingredients were identified for use in developing a 106-AN grout formulation, and 18 were subsequently obtained and tested. Four ingredients-Type II-LA (moderate heat of hydration) Portland cement, Class F fly ash, attapulgite 150 drilling clay, and ground air-cooled blast-furnace slag (GABFS) were selected for developing the 106-AN grout formulations. A mixture experiment was designed and conducted around the following formulation: 2.5 lb of cement per gallon, 1.2 lb of fly ash per gallon, 0.8 lb of attapulgite per gallon, and 3.5 lb of GABFS per gallon. Reduced empirical models were generated from the results of the mixture experiment. These models were used to recommend several grout formulations for 106-AN. Westinghouse Hanford Company selected one of these formulations to be verified for use with 106-AN and a backup formulation in case problems arise with the first choice

  3. Economic, energy, and environmental impacts of alcohol dehydration technology on biofuel production from brown algae

    International Nuclear Information System (INIS)

    Fasahati, Peyman; Liu, J. Jay

    2015-01-01

    This study evaluates the impact of alcohol recovery technology on the economics, energy consumption, and environment of bioethanol production from brown algae. The process under consideration is the anaerobic digestion of brown algae to produce VFAs (volatile fatty acids), which are then hydrogenated to produce mixed alcohols. Three alternative processes, i.e., hybrid pervaporation/distillation (PV), hybrid vapor-permeation/distillation (VP), and classical molecular-sieves/distillation (classical), are considered for the dehydration and recovery of ethanol. The alternatives are analyzed in terms of product value (i.e., minimum ethanol selling price – MESP), capital costs, energy consumption, and carbon footprint. For a plant scale of 400,000 ton/year of dry brown algae, the MESPs for the PV (Pervaporation), VP (vapor permeation), and classical processes were calculated to be $1.06/gal, $1.08/gal, and $1.24/gal, respectively. Results show that the PV, VP, and classical processes have $2.0, $2.6, and $4.6 million/year utility costs, respectively, for the recovery of alcohols and produce 23.1, 30.2, and 62.2 kton CO_2-eq/year greenhouse gases. Therefore, PV is more economical and environmentally friendly process, with lower MESP, CO_2 emissions, and utility requirements. A sensitivity analysis indicates that the selling price of the heavier alcohols and biomass price have the highest impact on the economics of bioethanol production from brown algae. - Highlights: • Biofuel production through anaerobic digestion of brown algae is assessed. • Three alternative dehydration technologies were considered for ethanol recovery. • MESP for PV, VP, and classic processes are 1.06, 1.08, and 1.24$/gal, respectively. • PV and VP were superior over classic process in terms of energy and GHG emissions. • PV has an energy cost of 20.2 mm$/y and GHG emissions of 23.1 kton CO_2-eq/year.

  4. Observatory wins GBP 10.6m contract

    CERN Multimedia

    Dalton, A W

    2003-01-01

    Funding has been secured for a revolutionary GBP 10.6 million telescope camera, SCUBA 2, to be built in Edinburgh. The instrument will be able to track much larger areas of sky more quickly and will replace the original Sub-millimetre Common User Bolometer Array camera which was also built in Edinburgh (1/2 page).

  5. Alternative fuel cycles

    International Nuclear Information System (INIS)

    Penn, W.J.

    1979-05-01

    Uranium resource utilization and economic considerations provide incentives to study alternative fuel cycles as future options to the PHWR natural uranium cycle. Preliminary studies to define the most favourable alternatives and their possible introduction dates are discussed. The important and uncertain components which influence option selection are reviewed, including nuclear capacity growth, uranium availability and demand, economic potential, and required technological developments. Finally, a summary of Ontario Hydro's program to further assess cycle selection and define development needs is given. (auth)

  6. 36 CFR 905.735-108 - Remedial and disciplinary action.

    Science.gov (United States)

    2010-07-01

    ... DEVELOPMENT CORPORATION STANDARDS OF CONDUCT General Provisions § 905.735-108 Remedial and disciplinary action... assignment; (3) Changes in the assigned duties of the individual; or (4) Disciplinary action. (b) Where the situation warrants some form of disciplinary action, the Chairman may choose from a wide range including a...

  7. 40 CFR 92.108 - Intake and cooling air measurements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Intake and cooling air measurements....108 Intake and cooling air measurements. (a) Intake air flow measurement. Measurement of the flow rate..., the measurement technique shall conform to the following: (1) The air flow measurement method used...

  8. Oral supplementation of Bifidobacterium longum strain BR-108 alters cecal microbiota by stimulating gut immune system in mice irrespectively of viability.

    Science.gov (United States)

    Makioka, Yuko; Tsukahara, Takamitsu; Ijichi, Tetsuo; Inoue, Ryo

    2018-03-20

    Effect on cecal microbiota and gene expression of various cytokines in ileal Peyer's patches and cecal tissues were compared between viable and heat-killed Bifidobacterium longum strain BR-108 (BR-108) using a mouse model. Irrespectively of viability, oral supplementation of BR-108 altered the cecal microbiota and stimulated gene expression of cytokines such as IL-6 and IL-10 in ileal Peyer's patches and cecal tissue of mice. In addition, BR-108 supplementation significantly affected the relative abundance of bacterial genera and family, Oscillospira, Bacteroides and S24-7. The abundance of these bacterial genera and family strongly correlated with gene expression induced by BR-108. This study demonstrated that the effect of heat-killed BR-108 on the mouse cecal microbiota is similar to that of viable BR-108, most likely due to stimulation of the gut immune system by both heat-killed and viable BR-108 is also similar.

  9. CR108, a novel vitamin K3 derivative induces apoptosis and breast tumor inhibition by reactive oxygen species and mitochondrial dysfunction

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Chun-Ru [Department of Biological Science and Technology, National Chiao Tung University, Hsinchu 30068, Taiwan (China); Liao, Wei-Siang [Institute of Molecular Medicine and Bioengineering, National Chiao Tung University, Hsinchu 30068, Taiwan (China); Wu, Ya-Hui [Department of Biological Science and Technology, National Chiao Tung University, Hsinchu 30068, Taiwan (China); Murugan, Kaliyappan [Department of Chemistry, National Dong Hwa University, Hualien 974, Taiwan (China); Chen, Chinpiao, E-mail: chinpiao@mail.ndhu.edu.tw [Department of Chemistry, National Dong Hwa University, Hualien 974, Taiwan (China); Chao, Jui-I, E-mail: jichao@faculty.nctu.edu.tw [Department of Biological Science and Technology, National Chiao Tung University, Hsinchu 30068, Taiwan (China); Institute of Molecular Medicine and Bioengineering, National Chiao Tung University, Hsinchu 30068, Taiwan (China)

    2013-12-15

    Vitamin K3 derivatives have been shown to exert anticancer activities. Here we show a novel vitamin K3 derivative (S)-2-(2-hydroxy-3-methylbutylthio)naphthalene-1,4-dione, which is named as CR108 that induces apoptosis and tumor inhibition through reactive oxygen species (ROS) and mitochondrial dysfunction in human breast cancer. CR108 is more effective on the breast cancer cell death than other vitamin K3 derivatives. Moreover, CR108 induced apoptosis in both the non-HER-2-overexpressed MCF-7 and HER-2-overexpressed BT-474 breast cancer cells. CR108 caused the loss of mitochondrial membrane potential, cytochrome c released from mitochondria to cytosol, and cleaved PARP proteins for apoptosis induction. CR108 markedly increased ROS levels in breast cancer cells. N-acetylcysteine (NAC), a general ROS scavenger, completely blocked the CR108-induced ROS levels, mitochondrial dysfunction and apoptosis. Interestingly, CR108 increased the phosphorylation of p38 MAP kinase but conversely inhibited the survivin protein expression. NAC treatment prevented the activation of p38 MAP kinase and rescued the survivin protein levels. SB202190, a specific p38 MAP kinase inhibitor, recovered the survivin protein levels and attenuated the cytotoxicity of CR108-treated cells. Furthermore, CR108 inhibited the xenografted human breast tumor growth in nude mice. Together, we demonstrate that CR108 is a novel vitamin K3 derivative that induces apoptosis and tumor inhibition by ROS production and mitochondrial dysfunction and associates with the phosphorylation of p38 MAP kinase and the inhibition of survivin in the human breast cancer. - Highlights: • CR108 is more effective on the cell death than other vitamin K3 derivatives. • CR108 induces apoptosis and tumor inhibition by ROS and mitochondrial dysfunction. • CR108 induces apoptosis by p38 kinase activation and survivin inhibition. • CR108 is a potent vitamin K3 analog that can develop for breast cancer therapy.

  10. CR108, a novel vitamin K3 derivative induces apoptosis and breast tumor inhibition by reactive oxygen species and mitochondrial dysfunction

    International Nuclear Information System (INIS)

    Yang, Chun-Ru; Liao, Wei-Siang; Wu, Ya-Hui; Murugan, Kaliyappan; Chen, Chinpiao; Chao, Jui-I

    2013-01-01

    Vitamin K3 derivatives have been shown to exert anticancer activities. Here we show a novel vitamin K3 derivative (S)-2-(2-hydroxy-3-methylbutylthio)naphthalene-1,4-dione, which is named as CR108 that induces apoptosis and tumor inhibition through reactive oxygen species (ROS) and mitochondrial dysfunction in human breast cancer. CR108 is more effective on the breast cancer cell death than other vitamin K3 derivatives. Moreover, CR108 induced apoptosis in both the non-HER-2-overexpressed MCF-7 and HER-2-overexpressed BT-474 breast cancer cells. CR108 caused the loss of mitochondrial membrane potential, cytochrome c released from mitochondria to cytosol, and cleaved PARP proteins for apoptosis induction. CR108 markedly increased ROS levels in breast cancer cells. N-acetylcysteine (NAC), a general ROS scavenger, completely blocked the CR108-induced ROS levels, mitochondrial dysfunction and apoptosis. Interestingly, CR108 increased the phosphorylation of p38 MAP kinase but conversely inhibited the survivin protein expression. NAC treatment prevented the activation of p38 MAP kinase and rescued the survivin protein levels. SB202190, a specific p38 MAP kinase inhibitor, recovered the survivin protein levels and attenuated the cytotoxicity of CR108-treated cells. Furthermore, CR108 inhibited the xenografted human breast tumor growth in nude mice. Together, we demonstrate that CR108 is a novel vitamin K3 derivative that induces apoptosis and tumor inhibition by ROS production and mitochondrial dysfunction and associates with the phosphorylation of p38 MAP kinase and the inhibition of survivin in the human breast cancer. - Highlights: • CR108 is more effective on the cell death than other vitamin K3 derivatives. • CR108 induces apoptosis and tumor inhibition by ROS and mitochondrial dysfunction. • CR108 induces apoptosis by p38 kinase activation and survivin inhibition. • CR108 is a potent vitamin K3 analog that can develop for breast cancer therapy

  11. Development of grout formulations for 106-AN waste: Mixture-experiment results and analysis

    International Nuclear Information System (INIS)

    Spence, R.D.; McDaniel, E.W.; Anderson, C.M.; Lokken, R.O.; Piepel, G.F.

    1993-09-01

    Twenty potential ingredients were identified for use in developing a 106-AN grout formulation, and 18 were subsequently obtained and tested. Four ingredients: Type II-LA (moderate heat of hydration) Portland cement, Class F fly ash, attapulgite 150 drilling clay, and ground air-cooled blast-furnace slag (GABFS) -- were selected for developing the 106-AN grout formulations. A mixture experiment was designed and conducted around the following formulation: 2.5 lb of cement per gallon, 1.2 lb of fly ash per gallon, 0.8 lb of attapulgite per gallon, and 3.5 lb of GABFS per gallon. Reduced empirical models were generated from the results of the mixture experiment. These models were used to recommend several grout formulations for 106-AN. Westinghouse Hanford Company selected one of these formulations to be verified for use with 106-AN and a backup formulation in case problems arise with the first choice. This report presents the mixture-experimental results and leach data

  12. 5 CFR 177.108 - Referral to Department of Justice.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Referral to Department of Justice. 177... ADMINISTRATIVE CLAIMS UNDER THE FEDERAL TORT CLAIMS ACT § 177.108 Referral to Department of Justice. When Department of Justice approval or consultation is required, or the advice of the Department of Justice is...

  13. 46 CFR 108.901 - Muster list and emergency instructions.

    Science.gov (United States)

    2010-10-01

    ... UNITS DESIGN AND EQUIPMENT Muster List § 108.901 Muster list and emergency instructions. (a) General...) Each muster list must specify the actions to be taken by the crew and industrial personnel when each... specify the duties assigned to the different industrial personnel and members of the crew that include— (i...

  14. 13 CFR 108.230 - Private Capital for NMVC Companies.

    Science.gov (United States)

    2010-01-01

    ... VENTURE CAPITAL (âNMVCâ) PROGRAM Qualifications for the NMVC Program Capitalizing A Nmvc Company § 108.230 Private Capital for NMVC Companies. (a) General. Private Capital means the contributed capital of a NMVC... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Private Capital for NMVC Companies...

  15. 46 CFR 108.641 - Instructions for changing steering gear.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Instructions for changing steering gear. 108.641 Section... steering gear. Instructions stating, in order, the different steps to be taken for changing to emergency and secondary steering gear must be posted in the steering gear room and at each secondary steering...

  16. Chemical and chemically-related considerations associated with sluicing tank C-106 waste to tank AY-102

    International Nuclear Information System (INIS)

    Reynolds, D.A.

    1997-01-01

    New data on tank 241-C-106 were obtained from grab sampling and from compatibility testing of tank C-106 and tank AY-102 wastes. All chemistry-associated and other compatibility Information compiled in this report strongly suggests that the sluicing of the contents of tank C-106, in accord with appropriate controls, will pose no unacceptable risk to workers, public safety, or the environment. In addition, it is expected that the sluicing operation will successfully resolve the High-Heat Safety Issue for tank C-106

  17. 5 CFR 2606.106 - OGE employee Privacy Act rules of conduct and responsibilities.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false OGE employee Privacy Act rules of conduct and responsibilities. 2606.106 Section 2606.106 Administrative Personnel OFFICE OF GOVERNMENT ETHICS... requirement to inform each individual asked to supply information to be maintained in a system of records the...

  18. Tank characterization report for single shell tank 241-SX-108

    Energy Technology Data Exchange (ETDEWEB)

    Eggers, R.F., Westinghouse Hanford

    1996-07-11

    This document summarizes the information on the historical uses, present status, and the sampling and analysis results of waste stored in tank 241-SX-108. This report supports the requirements of Tri-Party Agreement Milestone M-44-09.

  19. Tank characterization report for single-shell tank 241-T-108

    International Nuclear Information System (INIS)

    Baldwin, J.H.

    1996-01-01

    This document summarizes the information on the historical uses, present status, and the sampling and analysis results of waste stored in Tank 241-T-108. This report supports the requirements of Tri-Party Agreement Milestone M-44-09

  20. 13 CFR 108.660 - Other items required to be filed by NMVC Company with SBA.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Other items required to be filed by NMVC Company with SBA. 108.660 Section 108.660 Business Credit and Assistance SMALL BUSINESS... other person who was required by SBA to complete a personal history statement, is charged with or...

  1. Tank 241-C-108 vapor sampling and analysis tank characterization report. Revision 1

    International Nuclear Information System (INIS)

    Huckaby, J.L.

    1995-01-01

    Tank 241-C-108 headspace gas and vapor samples were collected and analyzed to help determine the potential risks to tank farm workers due to fugitive emissions from the tank. The drivers and objectives of waste tank headspace sampling and analysis are discussed in open-quotes Program Plan for the Resolution of Tank Vapor Issues.close quotes Tank 241-C-108 was vapor sampled in accordance with open-quotes Data Quality Objectives for Generic In-Tank Health and Safety Issue Resolution.close quotes

  2. Tank 241-BY-108 vapor sampling and analysis tank characterization report. Revision 1

    International Nuclear Information System (INIS)

    Huckaby, J.L.

    1995-01-01

    Tank 241-BY-108 headspace gas and vapor samples were collected and analyzed to help determine the potential risks to tank farm workers due to fugitive emissions from the tank. The drivers and objectives of waste tank headspace sampling and analysis are discussed in ''Program Plan for the Resolution of Tank Vapor Issues'' (Osborne and Huckaby 1994). Tank 241-BY-108 was vapor sampled in accordance with ''Data Quality Objectives for Generic In-Tank Health and Safety Issue Resolution (Osborne et al., 1994)

  3. Tank characterization report for single-shell tank 241-B-108

    International Nuclear Information System (INIS)

    Schreiber, R.D.

    1997-01-01

    This document summarizes the information on the historical uses, present status, and the sampling and analysis results of waste stored in Tank 241-B-108. This report supports the requirements of the Tri-Party Agreement Milestone M-44-05

  4. 13 CFR 106.202 - What are the minimum requirements applicable to Cosponsored Activities?

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What are the minimum requirements applicable to Cosponsored Activities? 106.202 Section 106.202 Business Credit and Assistance SMALL BUSINESS... constitute or imply an endorsement by SBA of any Cosponsor or any Cosponsor's products or services; (c) Any...

  5. Tank 241-C-106 past-practice sluicing waste retrieval, Hanford Site, Richland, Washington. Environmental Assessment

    International Nuclear Information System (INIS)

    1995-02-01

    The US Department of Energy (DOE) needs to take action to eliminate safety concerns with storage of the high-heat waste in Tank 241-C-106 (Tank C-106), and demonstrate a tank waste retrieval technology. This Environmental Assessment (EA) was prepared to analyze the potential impacts associated with the proposed action, past-practice sluicing of Tank C-106, an underground single-shell tank (SST). Past-practice sluicing is defined as the mode of waste retrieval used extensively in the past at the Hanford Site on the large underground waste tanks, and involves introducing a high-volume, low-pressure stream of liquid to mobilize sludge waste prior to pumping. It is proposed to retrieve the waste from Tank C-106 because this waste is classified not only as transuranic and high-level, but also as high-heat, which is caused by the radioactive decay of strontium. This waste characteristic has led DOE to place Tank C-106 on the safety ''Watchlist.''

  6. 13 CFR 108.2006 - Evaluation and selection of SSBICs.

    Science.gov (United States)

    2010-01-01

    ... likelihood that and the time frame within which the SSBIC will be able to raise the Regulatory Capital it intends to raise and obtain the matching resources described in § 108.2005(b) and (g); (d) The need for... VENTURE CAPITAL (âNMVCâ) PROGRAM Requirements and Procedures for Operational Assistance Grants to NMVC...

  7. Improvement of phytoremediation of an aged petroleum hydrocarbon-contaminated soil by Rhodococcus erythropolis CD 106 strain.

    Science.gov (United States)

    Płociniczak, Tomasz; Fic, Ewa; Pacwa-Płociniczak, Magdalena; Pawlik, Małgorzata; Piotrowska-Seget, Zofia

    2017-07-03

    The aim of this study was to assess the impact of soil inoculation with the Rhodococcus erythropolis CD 106 strain on the effectiveness of the phytoremediation of an aged hydrocarbon-contaminated [approx. 1% total petroleum hydrocarbon (TPH)] soil using ryegrass (Lolium perenne). The introduction of CD 106 into the soil significantly increased the biomass of ryegrass and the removal of hydrocarbons in planted soil. The fresh weight of the shoots and roots of plants inoculated with CD 106 increased by 49% and 30%, respectively. After 210 days of the experiment, the concentration of TPH was reduced by 31.2%, whereas in the planted, non-inoculated soil, it was reduced by 16.8%. By contrast, the concentration of petroleum hydrocarbon decreased by 18.7% in non-planted soil bioaugmented with the CD 106 strain. The rifampicin-resistant CD 106 strain survived after inoculation into soil and was detected in the soil during the entire experimental period, but the number of CD 106 cells decreased constantly during the enhanced phytoremediation and bioaugmentation experiments. The plant growth-promoting and hydrocarbon-degrading properties of CD 106, which are connected with its long-term survival and limited impact on autochthonous microflora, make this strain a good candidate for improving the phytoremediation efficiency of soil contaminated with hydrocarbons.

  8. 42 CFR 441.106 - Comprehensive mental health program.

    Science.gov (United States)

    2010-10-01

    ... health and public welfare resources; including— (i) Community mental health centers; (ii) Nursing homes... 42 Public Health 4 2010-10-01 2010-10-01 false Comprehensive mental health program. 441.106... Comprehensive mental health program. (a) If the plan includes services in public institutions for mental...

  9. 33 CFR 106.140 - Maritime Security (MARSEC) Directive.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Maritime Security (MARSEC... SECURITY MARITIME SECURITY MARINE SECURITY: OUTER CONTINENTAL SHELF (OCS) FACILITIES General § 106.140 Maritime Security (MARSEC) Directive. All OCS facility owners or operators subject to this part must comply...

  10. 49 CFR 176.108 - Supervision of Class 1 (explosive) materials during loading, unloading, handling and stowage.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Supervision of Class 1 (explosive) materials during loading, unloading, handling and stowage. 176.108 Section 176.108 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS...

  11. Tank 241-B-106 tank characterization plan. Revision 1

    International Nuclear Information System (INIS)

    Homi, C.S.

    1995-01-01

    This document is a plan that identifies the information needed to address relevant issues concerning short-term and long-term safe storage and long-term management of Single-Shell Tank (SST) 241-B-106

  12. 49 CFR 230.108 - Steam locomotive leading and trailing trucks.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Steam locomotive leading and trailing trucks. 230... RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION STEAM LOCOMOTIVE INSPECTION AND MAINTENANCE STANDARDS Steam Locomotives and Tenders Trucks, Frames and Equalizing System § 230.108 Steam locomotive leading...

  13. 7 CFR 786.106 - Determination of losses incurred.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Determination of losses incurred. 786.106 Section 786... Determination of losses incurred. (a) Eligible payable losses are calculated on a dairy operation by dairy..., dairy production losses incurred by producers under this part are determined on the established history...

  14. On measuring technological possibilities by hypervolumes

    DEFF Research Database (Denmark)

    Asmild, Mette; Hougaard, Jens Leth

    2016-01-01

    Measuring technological possibilities is a somewhat neglected topic in the productivity analysis literature. We discuss existing methods as well as an obvious alternative measure based on hypervolumes. We illustrate the use of a volume-based measure on an empirical case of demolition projects fro...... two different companies and suggest ways of overcoming some issues related to the practical implementation. Finally, we discuss pros and cons of the various approaches.......Measuring technological possibilities is a somewhat neglected topic in the productivity analysis literature. We discuss existing methods as well as an obvious alternative measure based on hypervolumes. We illustrate the use of a volume-based measure on an empirical case of demolition projects from...

  15. Transcriptome analysis of Phelipanche aegyptiaca seed germination mechanisms stimulated by fluridone, TIS108, and GR24.

    Directory of Open Access Journals (Sweden)

    Ya Zhou Bao

    Full Text Available P. aegyptiaca is one of the most destructive root parasitic plants worldwide, causing serious damage to many crop species. Under natural conditions P. aegyptiaca seeds must be conditioned and then stimulated by host root exudates before germinating. However, preliminary experiments indicated that TIS108 (a triazole-type inhibitor of strigolactone and fluridone (FL, an inhibitor of carotenoid-biosynthesis both stimulated the germination of P. aegyptiaca seeds without a water preconditioning step (i.e. unconditioned seeds. The objective of this study was to use deep RNA sequencing to learn more about the mechanisms by which TIS108 and FL stimulate the germination of unconditioned P. aegyptiaca seeds. Deep RNA sequencing was performed to compare the mechanisms of germination in the following treatments: (i unconditioned P. aegyptiaca seeds with no other treatment, (ii unconditioned seeds treated with 100 mg/L TIS108, (iii unconditioned seeds treated with 100 mg/L FL + 100 mg/L GA3, (iv conditioned seeds treated with sterile water, and (v conditioned seeds treated with 0.03 mg/L GR24. The de novo assembled transcriptome was used to analyze transcriptional dynamics during seed germination. The key gene categories involved in germination were also identified. The results showed that only 119 differentially expressed genes were identified in the conditioned treatment vs TIS108 treatment. This indicated that the vast majority of conditions for germination were met during the conditioning stage. Abscisic acid (ABA and gibberellic acid (GA played important roles during P. aegyptiaca germination. The common pathway of TIS108, FL+GA3, and GR24 in stimulating P. aegyptiaca germination was the simultaneous reduction in ABA concentrations and increase GA concentrations. These results could potentially aid the identification of more compounds that are capable of stimulating P. aegyptiaca germination. Some potential target sites of TIS108 were also identified in

  16. Transcriptome analysis of Phelipanche aegyptiaca seed germination mechanisms stimulated by fluridone, TIS108, and GR24.

    Science.gov (United States)

    Bao, Ya Zhou; Yao, Zhao Qun; Cao, Xiao Lei; Peng, Jin Feng; Xu, Ying; Chen, Mei Xiu; Zhao, Si Feng

    2017-01-01

    P. aegyptiaca is one of the most destructive root parasitic plants worldwide, causing serious damage to many crop species. Under natural conditions P. aegyptiaca seeds must be conditioned and then stimulated by host root exudates before germinating. However, preliminary experiments indicated that TIS108 (a triazole-type inhibitor of strigolactone) and fluridone (FL, an inhibitor of carotenoid-biosynthesis) both stimulated the germination of P. aegyptiaca seeds without a water preconditioning step (i.e. unconditioned seeds). The objective of this study was to use deep RNA sequencing to learn more about the mechanisms by which TIS108 and FL stimulate the germination of unconditioned P. aegyptiaca seeds. Deep RNA sequencing was performed to compare the mechanisms of germination in the following treatments: (i) unconditioned P. aegyptiaca seeds with no other treatment, (ii) unconditioned seeds treated with 100 mg/L TIS108, (iii) unconditioned seeds treated with 100 mg/L FL + 100 mg/L GA3, (iv) conditioned seeds treated with sterile water, and (v) conditioned seeds treated with 0.03 mg/L GR24. The de novo assembled transcriptome was used to analyze transcriptional dynamics during seed germination. The key gene categories involved in germination were also identified. The results showed that only 119 differentially expressed genes were identified in the conditioned treatment vs TIS108 treatment. This indicated that the vast majority of conditions for germination were met during the conditioning stage. Abscisic acid (ABA) and gibberellic acid (GA) played important roles during P. aegyptiaca germination. The common pathway of TIS108, FL+GA3, and GR24 in stimulating P. aegyptiaca germination was the simultaneous reduction in ABA concentrations and increase GA concentrations. These results could potentially aid the identification of more compounds that are capable of stimulating P. aegyptiaca germination. Some potential target sites of TIS108 were also identified in our

  17. Fabrication of a novel hydrogen peroxide biosensor based on Au-(PEO106PPO70PEO106) hairy nanospheres

    International Nuclear Information System (INIS)

    Ni Yalong; Wang Yan; Zhang Guohui; Shen Jian; Zhao Wenbo; Huang Xiaohua

    2012-01-01

    In this case, the Au-F127 (triblock copolymer PEO 106 PPO 70 PEO 106 , PEO is short for polyethylene oxide and PPO is the abbreviation of polypropene oxide) hybrid hairy nanospheres were obtained by the redox reaction using pluronic F127 and HAuCl 4 as precursor. A novel hemoglobin (Hb) biosensor was fabricated by immobilizing the Hb onto the Au-F127 film on the surface of glassy carbon electrode (GCE). The Au-F127 nanocomposites and Hb were characterized by transmission electron microscopy (TEM), polycrystalline electron diffraction ring pattern and ultra-violet visible spectra (UV–vis). UV–vis spectra suggested that Hb in the film could keep its native secondary structure. The performances of Hb/(Au-F127) on GCE were characterized with cyclic voltammetry (CV) and typical amperometric response (i–t) measurements. The immobilized Hb maintained its bioactivity and displayed an excellent electrochemical behavior with a formal potential of −339 mV. The resulting electrode showed an electrocatalytic activity to hydrogen peroxide (H 2 O 2 ). The linear response range of the H 2 O 2 biosensor was from 3.0 × 10 −7 to 5.7 × 10 −4 M with a low detection limit of 4.0 × 10 −8 M.

  18. Telemetry Standards, RCC Standard 106-17. Chapter 3. Frequency Division Multiplexing Telemetry Standards

    Science.gov (United States)

    2017-07-01

    Standard 106-17 Chapter 3, July 2017 3-5 Table 3-4. Constant-Bandwidth FM Subcarrier Channels Frequency Criteria\\Channels: A B C D E F G H Deviation ...Telemetry Standards , RCC Standard 106-17 Chapter 3, July 2017 3-i CHAPTER 3 Frequency Division Multiplexing Telemetry Standards Acronyms...Frequency Division Multiplexing Telemetry Standards ................................ 3-1 3.1 General

  19. 76 FR 73614 - Lock 14 Hydro Partners; FFP Project 106 LLC; Notice of Competing Preliminary Permit Applications...

    Science.gov (United States)

    2011-11-29

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project Nos. 13213-002; 14271-000] Lock 14 Hydro Partners; FFP Project 106 LLC; Notice of Competing Preliminary Permit Applications Accepted..., 2011, Lock 14 Hydro Partners (Lock 14), and FFP Project 106 LLC (FFP 106) filed preliminary permit...

  20. CR108, a novel vitamin K3 derivative induces apoptosis and breast tumor inhibition by reactive oxygen species and mitochondrial dysfunction.

    Science.gov (United States)

    Yang, Chun-Ru; Liao, Wei-Siang; Wu, Ya-Hui; Murugan, Kaliyappan; Chen, Chinpiao; Chao, Jui-I

    2013-12-15

    Vitamin K3 derivatives have been shown to exert anticancer activities. Here we show a novel vitamin K3 derivative (S)-2-(2-hydroxy-3-methylbutylthio)naphthalene-1,4-dione, which is named as CR108 that induces apoptosis and tumor inhibition through reactive oxygen species (ROS) and mitochondrial dysfunction in human breast cancer. CR108 is more effective on the breast cancer cell death than other vitamin K3 derivatives. Moreover, CR108 induced apoptosis in both the non-HER-2-overexpressed MCF-7 and HER-2-overexpressed BT-474 breast cancer cells. CR108 caused the loss of mitochondrial membrane potential, cytochrome c released from mitochondria to cytosol, and cleaved PARP proteins for apoptosis induction. CR108 markedly increased ROS levels in breast cancer cells. N-acetylcysteine (NAC), a general ROS scavenger, completely blocked the CR108-induced ROS levels, mitochondrial dysfunction and apoptosis. Interestingly, CR108 increased the phosphorylation of p38 MAP kinase but conversely inhibited the survivin protein expression. NAC treatment prevented the activation of p38 MAP kinase and rescued the survivin protein levels. SB202190, a specific p38 MAP kinase inhibitor, recovered the survivin protein levels and attenuated the cytotoxicity of CR108-treated cells. Furthermore, CR108 inhibited the xenografted human breast tumor growth in nude mice. Together, we demonstrate that CR108 is a novel vitamin K3 derivative that induces apoptosis and tumor inhibition by ROS production and mitochondrial dysfunction and associates with the phosphorylation of p38 MAP kinase and the inhibition of survivin in the human breast cancer. © 2013.

  1. Transfer reactions and multiple Coulomb excitation in the $^{100}$Sn Region

    CERN Multimedia

    It is proposed to continue our REX-ISOLDE program in the $^{100}$Sn region at HIE-ISOLDE at ~5 MeV/u. Earlier measurements, with a precision of 10-20%, at 3 MeV/u with REX-ISOLDE point to a deviation between the measured B(E2) values for the first excited 2$^{+}$ states in $^{110,108,106}$Sn compared to theoretical predictions. In addition, the trend of B(E2) values for the lighter isotopes, in particular $^{106}$Sn, appear to differ between low- and high-energy measurements. In line with our letter-of-intent we aim in a first step to address the electromagnetic properties of the first 2$^{+}$and 4$^{+}$ states in $^{110,108,106}$Sn using Coulomb excitation. In these measurements we will directly access the lifetimes of the first excited 4$^{+}$ states in $^{110,108,106}$Sn for the first time. The yield of $^{104}$Sn from the LaC$_{x}$ target will be revisited to clarify if the new solid state RILIS gives sufficient yield to expand the measurements to this isotope. Following this proposal we plan similar meas...

  2. Braquiterapia com rutênio-106 em melanomas uveais - resultados preliminares: experiência uni-institucional Ruthenium-106 brachytherapy for uveal melanomas - preliminary results: a single institutional experience

    Directory of Open Access Journals (Sweden)

    Rodrigo Souza Dias

    2007-04-01

    Full Text Available OBJETIVO: Analisar os resultados preliminares da braquiterapia com rutênio-106 em pacientes portadores de melanomas uveais. MATERIAIS E MÉTODOS: No período de abril de 2002 a julho de 2003, 20 pacientes com diagnóstico de melanoma uveal foram tratados com braquiterapia com rutênio-106. A dose calculada no ápice tumoral variou de 55 Gy a 100 Gy. Pacientes com lesões com altura maior que 5 mm foram submetidos a termoterapia transpupilar concomitante à colocação da placa oftálmica. RESULTADOS: Quanto à localização da lesão, esta se encontrava na coróide em 75% dos casos, na íris em 15% e no corpo ciliar em 10% dos pacientes. Com seguimento mediano de 19 meses, a sobrevida livre de progressão para a braquiterapia e para a associação com a termoterapia transpupilar foi de 69% e 87%, respectivamente. Observou-se redução significante da altura tumoral após o tratamento. Nenhum dos pacientes foi submetido a enucleação. CONCLUSÃO: Nossos resultados preliminares mostram que a braquiterapia com rutênio-106 é uma opção adequada para o tratamento conservador de melanomas uveais em termos de controle local, manutenção do globo ocular e visão útil, com índice aceitável de complicações.OBJECTIVE: To analyze the early response of uveal melanomas in patients treated with ruthenium-106 brachytherapy. MATERIALS AND METHODS: In the period between April 2002 and July 2003, 20 patients diagnosed with uveal melanoma were submitted to ruthenium-106 brachytherapy. The calculated dose delivered at the apex of the tumor ranged between 55 Gy and 100 Gy. Patients with lesions greater than 5 mm were submitted to transpupillary thermotherapy concomitantly with ophthalmic plaque insertion. RESULTS: As regards the lesions site, 75% of the lesions were located in the choroid, 15% in the iris, and the remainder 10% in the ciliary body. In a median 19-month-follow-up, the progression-free survival for brachytherapy was 69%, and 87% for

  3. 21 CFR 250.108 - Potassium permanganate preparations as prescription drugs.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Potassium permanganate preparations as... or Prescription Status of Specific Drugs § 250.108 Potassium permanganate preparations as... women resulting from the misuse of potassium permanganate in an effort to induce abortion. Reports from...

  4. 40 CFR 81.108 - Columbia Intrastate Air Quality Control Region.

    Science.gov (United States)

    2010-07-01

    ... Quality Control Regions § 81.108 Columbia Intrastate Air Quality Control Region. The Columbia Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Columbia Intrastate Air Quality...

  5. 41 CFR 105-64.106 - What is GSA's policy on information accuracy in a system of records?

    Science.gov (United States)

    2010-07-01

    ... information accuracy in a system of records? 105-64.106 Section 105-64.106 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION... Responsibilities § 105-64.106 What is GSA's policy on information accuracy in a system of records? System managers...

  6. Pheromone based alternative route planning

    Directory of Open Access Journals (Sweden)

    Liangbing Feng

    2016-08-01

    Full Text Available In this work, we propose an improved alternative route calculation based on alternative figures, which is suitable for practical environments. The improvement is based on the fact that the main traffic route is the road network skeleton in a city. Our approach using nodes may generate a higher possibility of overlapping. We employ a bidirectional Dijkstra algorithm to search the route. To measure the quality of an Alternative Figures (AG, three quotas are proposed. The experiment results indicate that the improved algorithm proposed in this paper is more effective than others.

  7. 42 CFR 424.106 - Criteria for determining whether the hospital was the most accessible.

    Science.gov (United States)

    2010-10-01

    ... the most accessible. 424.106 Section 424.106 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES... whether the hospital was the most accessible. (a) Basic requirement. (1) The hospital must be the most... nonparticipating hospital was the most accessible hospital: (1) The personal preference of the beneficiary, the...

  8. 40 CFR 266.108 - Small quantity on-site burner exemption.

    Science.gov (United States)

    2010-07-01

    ...) SOLID WASTES (CONTINUED) STANDARDS FOR THE MANAGEMENT OF SPECIFIC HAZARDOUS WASTES AND SPECIFIC TYPES OF HAZARDOUS WASTE MANAGEMENT FACILITIES Hazardous Waste Burned in Boilers and Industrial Furnaces § 266.108... burn hazardous waste in an on-site boiler or industrial furnace are exempt from the requirements of...

  9. 7 CFR 1710.106 - Uses of loan funds.

    Science.gov (United States)

    2010-01-01

    ... and Basic Policies § 1710.106 Uses of loan funds. (a) Funds from loans made or guaranteed by RUS may be used to finance: (1) Distribution facilities. (i) The construction of new distribution facilities... station service, and the borrower is unable to finance the acquisition from other sources. See § 1710.107...

  10. 78 FR 49318 - Availability of Draft Advisory Circular (AC) 90-106A and AC 20-167A

    Science.gov (United States)

    2013-08-13

    ...] Availability of Draft Advisory Circular (AC) 90-106A and AC 20- 167A AGENCY: Federal Aviation Administration... of draft Advisory Circular (AC) 90-106A, Enhanced Flight Vision Systems and draft AC 20- 167A... Federal holidays. FOR FURTHER INFORMATION CONTACT: For technical questions concerning draft AC 90-106A...

  11. Are behaviors at one alternative in concurrent schedules independent of contingencies at the other alternative?

    Science.gov (United States)

    MacDonall, James S

    2017-09-01

    Some have reported changing the schedule at one alternative of a concurrent schedule changed responding at the other alternative (Catania, 1969), which seems odd because no contingencies were changed there. When concurrent schedules are programmed using two schedules, one associated with each alternative that operate continuously, changing the schedule at one alternative also changes the switch schedule at the other alternative. Thus, changes in responding at the constant alternative could be due to the change in the switch schedule. To assess this possibility, six rats were exposed to a series of conditions that alternated between pairs of interval schedules at both alternatives and a pair of interval schedules at one, constant, alternative and a pair of extinction schedules at the other alternative. Comparing run lengths, visit durations and response rates at the constant alternative in the alternating conditions did not show consistent increases and decreases when a strict criterion for changes was used. Using a less stringent definition (any change in mean values) showed changes. The stay/switch analysis suggests it may be inaccurate to apply behavioral contrast to procedures that change from concurrent variable-interval variable-interval schedules to concurrent variable-interval extinction schedules because the contingencies in neither alternative are constant. © 2017 Society for the Experimental Analysis of Behavior.

  12. 77 FR 7613 - Dow Chemical Company; Dow Chemical TRIGA Research Reactor; Facility Operating License No. R-108

    Science.gov (United States)

    2012-02-13

    ... NUCLEAR REGULATORY COMMISSION [Docket No. 50-264; NRC-2012-0026] Dow Chemical Company; Dow Chemical TRIGA Research Reactor; Facility Operating License No. R-108 AGENCY: Nuclear Regulatory Commission... Facility Operating License No. R-108 (``Application''), which currently authorizes the Dow Chemical Company...

  13. bHLH106 Integrates Functions of Multiple Genes through Their G-Box to Confer Salt Tolerance on Arabidopsis.

    Science.gov (United States)

    Ahmad, Aftab; Niwa, Yasuo; Goto, Shingo; Ogawa, Takeshi; Shimizu, Masanori; Suzuki, Akane; Kobayashi, Kyoko; Kobayashi, Hirokazu

    2015-01-01

    An activation-tagging methodology was applied to dedifferentiated calli of Arabidopsis to identify new genes involved in salt tolerance. This identified salt tolerant callus 8 (stc8) as a gene encoding the basic helix-loop-helix transcription factor bHLH106. bHLH106-knockout (KO) lines were more sensitive to NaCl, KCl, LiCl, ABA, and low temperatures than the wild-type. Back-transformation of the KO line rescued its phenotype, and over-expression (OX) of bHLH106 in differentiated plants exhibited tolerance to NaCl. Green fluorescent protein (GFP) fused with bHLH106 revealed that it was localized to the nucleus. Prepared bHLH106 protein was subjected to electrophoresis mobility shift assays against E-box sequences (5'-CANNTG-3'). The G-box sequence 5'-CACGTG-3' had the strongest interaction with bHLH106. bHLH106-OX lines were transcriptomically analyzed, and resultant up- and down-regulated genes selected on the criterion of presence of a G-box sequence. There were 198 genes positively regulated by bHLH106 and 36 genes negatively regulated; these genes possessed one or more G-box sequences in their promoter regions. Many of these genes are known to be involved in abiotic stress response. It is concluded that bHLH106 locates at a branching point in the abiotic stress response network by interacting directly to the G-box in genes conferring salt tolerance on plants.

  14. South African Medical Journal - Vol 106, No 9 (2016)

    African Journals Online (AJOL)

    Guest Editorial: Functional neurosurgery (part 2) · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. J.M.N. Enslin, 853. http://dx.doi.org/10.7196/SAMJ.2016.v106i8.11195 ...

  15. Tank 241-C-106 waste retrieval sluicing system process control plan

    Energy Technology Data Exchange (ETDEWEB)

    Carothers, K.G.

    1998-07-25

    Project W-320 has installed the Waste Retrieval Sluicing System at the 200 East Area on the Hanford Site to retrieve the sludge from single-shell tank 241-C-106 and transfer it into double-shell tank 241-AY-102. Operation of the WRSS process will resolve the high-heat safety issue for tank 241-C-106 and demonstrate a technology for the retrieval of single-shell tank wastes. This process control plan coordinates the technical operating requirements (primarily mass transfer, temperature, and flammable gas) for the sluicing operation and provides overall technical guidance for the retrieval activity.

  16. Tank 241-C-106 waste retrieval sluicing system process control plan

    International Nuclear Information System (INIS)

    Carothers, K.G.

    1998-01-01

    Project W-320 has installed the Waste Retrieval Sluicing System at the 200 East Area on the Hanford Site to retrieve the sludge from single-shell tank 241-C-106 and transfer it into double-shell tank 241-AY-102. Operation of the WRSS process will resolve the high-heat safety issue for tank 241-C-106 and demonstrate a technology for the retrieval of single-shell tank wastes. This process control plan coordinates the technical operating requirements (primarily mass transfer, temperature, and flammable gas) for the sluicing operation and provides overall technical guidance for the retrieval activity

  17. SOFIA/FORCAST OBSERVATIONS OF WARM DUST IN S106: A FRAGMENTED ENVIRONMENT

    Energy Technology Data Exchange (ETDEWEB)

    Adams, J. D. [Stratospheric Observatory for Infrared Astronomy, Universities Space Research Association, NASA/Armstrong Flight Research Center, 2825 East Avenue P, Palmdale, CA 93550 (United States); Herter, T. L.; Lau, R. M.; Hankins, M. [Department of Astronomy, Cornell University, Space Sciences Building, Ithaca, NY 14853 (United States); Hora, J. L.; Fazio, G. G.; Fernandez, A. Guzman; Keto, E. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Schneider, N.; Simon, R. [KOSMA, I. Physikalisches Institut, Universität zu Köln, Zülpicher Strasse 77, D-50937 Köln (Germany); Staguhn, J. G. [NASA/Goddard Space Flight Center, 8800 Greenbelt Road, Greenbelt, MD 20771 (United States); Smith, N. [Department of Astronomy, University of Arizona, 933 North Cherry Avenue, Tucson, AZ 85721-0065 (United States); Gehrz, R. D. [Minnesota Institute for Astrophysics, University of Minnesota, 116 Church Street SE, Minneapolis, MN 55455 (United States); Allen, L. E. [National Optical Astronomy Observatory, 950 North Cherry Avenue, Tucson, AZ 85719 (United States); Bontemps, S. [Université Bordeaux, LAB, UMR 5804, CNRS, F-33270, Floirac (France); Carey, S. J. [Spitzer Science Center, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125 (United States); Gutermuth, R. A. [Department of Astronomy, University of Massachusetts, LGRT-B 619E, 710 North Pleasant Street, Amherst, MA 01003-9305 (United States); Hill, T. [Joint ALMA Observatory, 3107 Alonso de Cordova, Vitacura, Santiago (Chile); Koenig, X. P. [Department of Astronomy, Yale University, New Haven, CT 06511 (United States); Kraemer, K. E. [Institute for Scientific Research, Boston College, Chestnut Hill, MA 02467 (United States); and others

    2015-11-20

    We present mid-IR (19–37 μm) imaging observations of S106 from SOFIA/FORCAST, complemented with IR observations from Spitzer/IRAC (3.6–8.0 μm), IRTF/MIRLIN (11.3 and 12.5 μm), and Herschel/PACS (70 and 160 μm). We use these observations, observations in the literature, and radiation transfer modeling to study the heating and composition of the warm (∼100 K) dust in the region. The dust is heated radiatively by the source S106 IR, with little contributions from grain–electron collisions and Lyα radiation. The dust luminosity is ≳(9.02 ± 1.01) × 10{sup 4} L{sub ⊙}, consistent with heating by a mid- to late-type O star. We find a temperature gradient (∼75–107 K) in the lobes, which is consistent with a dusty equatorial geometry around S106 IR. Furthermore, the SOFIA observations resolve several cool (∼65–70 K) lanes and pockets of warmer (∼75–90 K) dust in the ionization shadow, indicating that the environment is fragmented. We model the dust mass as a composition of amorphous silicates, amorphous carbon, big grains, very small grains, and polycyclic aromatic hydrocarbons. We present the relative abundances of each grain component for several locations in S106.

  18. 9 CFR 108.2 - Plot plans, blueprints, and legends required.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Plot plans, blueprints, and legends... REQUIREMENTS FOR LICENSED ESTABLISHMENTS § 108.2 Plot plans, blueprints, and legends required. Each applicant for an establishment license shall prepare a plot plan showing all buildings for each particular land...

  19. 13 CFR 108.820 - Financings in the form of guarantees.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Financings in the form of... VENTURE CAPITAL (âNMVCâ) PROGRAM Financing of Small Businesses by NMVC Companies Structuring Nmvc Company's Financing of Eligible Small Businesses § 108.820 Financings in the form of guarantees. (a) General...

  20. 13 CFR 108.210 - Minimum capital requirements for NMVC Companies.

    Science.gov (United States)

    2010-01-01

    ... NEW MARKETS VENTURE CAPITAL (âNMVCâ) PROGRAM Qualifications for the NMVC Program Capitalizing A Nmvc Company § 108.210 Minimum capital requirements for NMVC Companies. You must have Regulatory Capital of at... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Minimum capital requirements for...

  1. 27 CFR 26.106 - Marking containers of beer.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Marking containers of beer... Liquors and Articles in Puerto Rico Beer § 26.106 Marking containers of beer. Containers of beer of Puerto... brewer; the serial number, capacity, and size of the container; the kind of beer; and the serial number...

  2. Alternative and complementary medicine in cancer patient

    International Nuclear Information System (INIS)

    Reckova, M.

    2009-01-01

    The use of alternative and complementary medicine (CAM) in cancer patients is widespread and it is not surprising as the results gained by conventional treatments are not sufficient. However, the results from the studies with CAM are not always sufficient according to their testing in appropriate clinical studies. Another problem that is present in the use of CAM is the possibility of drug-drug interactions between conventional therapies and CAM. Thus, it is of utmost importance that the oncologist possess a good knowledge of available CAM and provide a sufficient time for discussion with the patient and his/her family about possible alternative treatments and any downside risks. The cornerstone for pertinent discussion is sufficient knowledge on the part of the oncologist about those alternative treatments that are usually presented in the media with incomplete information about their relevant clinical tests and side effects. The following article presents a review of the current alternative treatment methods with a focus on the alternative drugs that have already been clinically tested, and secondarily on the alternative drugs that have been used even without sufficient testing in clinical trials. (author)

  3. 26 CFR 509.106 - Control of a United States enterprise by a Swiss enterprise.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 19 2010-04-01 2010-04-01 false Control of a United States enterprise by a Swiss enterprise. 509.106 Section 509.106 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE... a United States enterprise by a Swiss enterprise. In effect, Article IV of the convention provides...

  4. Interband transitions in 106Pd, 152Sm, 152Gd and 182W

    International Nuclear Information System (INIS)

    Kartashov, V.M.; Oborovskij, A.I.; Troitskaya, A.G.

    1990-01-01

    Internal transitions in 106 Pd, 152 Sm, 152 Gd, 182 W nuclei, observed during decay of 152,152m Eu, 182,183 Ta, 106m Ag, are studied. The experimental characteristics of E0-transitions and E0-components of E0+M1+E2 type transitions in the studied nuclei, relative intensities of internal conversion electron lines during 182 Ta decay, multipolar composition and forbidden factor for 182 W and 183 W low-energy transitions, characteristics of transitions are presented

  5. Consider the Alternative: The Effects of Causal Knowledge on Representing and Using Alternative Hypotheses in Judgments under Uncertainty

    Science.gov (United States)

    Hayes, Brett K.; Hawkins, Guy E.; Newell, Ben R.

    2016-01-01

    Four experiments examined the locus of impact of causal knowledge on consideration of alternative hypotheses in judgments under uncertainty. Two possible loci were examined; overcoming neglect of the alternative when developing a representation of a judgment problem and improving utilization of statistics associated with the alternative…

  6. 13 CFR 108.1220 - Requirement for NMVC Company to file financial statements at the time of request for a draw.

    Science.gov (United States)

    2010-01-01

    ... file financial statements at the time of request for a draw. 108.1220 Section 108.1220 Business Credit... Nmvc Company § 108.1220 Requirement for NMVC Company to file financial statements at the time of... financial statement on Form 468 (Short Form); and (2) File a statement of no material adverse change in your...

  7. Removal design report for the 108-F Biological Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-09-01

    Most of the 100-F facilities were deactivated with the reactor and have since been demolished. Of the dozen or so reactor-related structures, only the 105-F Reactor Building and the 108-F Biology Laboratory remain standing today. The 108-F Biology Laboratory was intended to be used as a facility for the mixing and addition of chemicals used in the treatment of the reactor cooling water. Shortly after F Reactor began operation, it was determined that the facility was not needed for this purpose. In 1949, the building was converted for use as a biological laboratory. In 1962, the lab was expanded by adding a three-story annex to the original four-story structure. The resulting lab had a floor area of approximately 2,883 m{sup 2} (main building and annex) that operated until 1973. The building contained 47 laboratories, a number of small offices, a conference room, administrative section, lunch and locker rooms, and a heavily shielded, high-energy exposure cell. The purpose of this removal design report is to establish the methods of decontamination and decommissioning and the supporting functions associated with facility removal and disposal.

  8. Removal design report for the 108-F Biological Laboratory

    International Nuclear Information System (INIS)

    1997-09-01

    Most of the 100-F facilities were deactivated with the reactor and have since been demolished. Of the dozen or so reactor-related structures, only the 105-F Reactor Building and the 108-F Biology Laboratory remain standing today. The 108-F Biology Laboratory was intended to be used as a facility for the mixing and addition of chemicals used in the treatment of the reactor cooling water. Shortly after F Reactor began operation, it was determined that the facility was not needed for this purpose. In 1949, the building was converted for use as a biological laboratory. In 1962, the lab was expanded by adding a three-story annex to the original four-story structure. The resulting lab had a floor area of approximately 2,883 m 2 (main building and annex) that operated until 1973. The building contained 47 laboratories, a number of small offices, a conference room, administrative section, lunch and locker rooms, and a heavily shielded, high-energy exposure cell. The purpose of this removal design report is to establish the methods of decontamination and decommissioning and the supporting functions associated with facility removal and disposal

  9. 40 CFR 266.106 - Standards to control metals emissions.

    Science.gov (United States)

    2010-07-01

    ... WASTES (CONTINUED) STANDARDS FOR THE MANAGEMENT OF SPECIFIC HAZARDOUS WASTES AND SPECIFIC TYPES OF HAZARDOUS WASTE MANAGEMENT FACILITIES Hazardous Waste Burned in Boilers and Industrial Furnaces § 266.106... streams, including hazardous waste, fuels, and industrial furnace feed stocks shall not exceed the...

  10. Business System Planning Project, Alternatives Analysis

    International Nuclear Information System (INIS)

    EVOSEVICH, S.

    2000-01-01

    The CHG Chief Information Officer (CIO) requested a study of alternatives to the current business system computing environment. This Business Systems Planning (BSP) Project Alternatives Analysis document presents an analysis of the current Project Controls, Work Management, and Business Management systems environment and alternative solutions that support the business functions. The project team has collected requirements and priorities from stakeholders in each business area and documented them in the BSP System Requirements Specification (SRS), RPP-6297. The alternatives analysis process identifies and measures possible solutions in each of the business process areas against the requirements as documented in the SRS. The team gathered input from both internal and external sources to identify and grade the possible solutions. This document captures the results of that activity and recommends a suite of software products. This study was to select the best product based on how well the product met the requirements, not to determine the platform or hardware environment that would be used. Additional analysis documentation can be found in BSP project files

  11. Hanford Tank 241-C-106: Residual Waste Contaminant Release Model and Supporting Data

    International Nuclear Information System (INIS)

    Deutsch, William J.; Krupka, Kenneth M.; Lindberg, Michael J.; Cantrell, Kirk J.; Brown, Christopher F.; Schaef, Herbert T.

    2005-01-01

    CH2M HILL is producing risk/performance assessments to support the closure of single-shell tanks at the DOE's Hanford Site. As part of this effort, staff at PNNL were asked to develop release models for contaminants of concern that are present in residual sludge remaining in tank 241-C-106 (C-106) after final retrieval of waste from the tank. This report provides the information developed by PNNL

  12. The Shell Collapsar—A Possible Alternative to Black Holes

    Directory of Open Access Journals (Sweden)

    Trevor W. Marshall

    2016-10-01

    Full Text Available This article argues that a consistent description is possible for gravitationally collapsed bodies, in which collapse stops before the object reaches its gravitational radius, the density reaching a maximum close to the surface and then decreasing towards the centre. The way towards such a description was indicated in the classic Oppenheimer-Snyder (OS 1939 analysis of a dust star. The title of that article implied support for a black-hole solution, but the present article shows that the final OS density distribution accords with gravastar and other shell models. The parallel Oppenheimer-Volkoff (OV study of 1939 used the equation of state for a neutron gas, but could consider only stationary solutions of the field equations. Recently we found that the OV equation of state permits solutions with minimal rather than maximal central density, and here we find a similar topology for the OS dust collapsar; a uniform dust-ball which starts with large radius, and correspondingly small density, and collapses to a shell at the gravitational radius with density decreasing monotonically towards the centre. Though no longer considered central in black-hole theory, the OS dust model gave the first exact, time-dependent solution of the field equations. Regarded as a limiting case of OV, it indicates the possibility of neutron stars of unlimited mass with a similar shell topology. Progress in observational astronomy will distinguish this class of collapsars from black holes.

  13. Decreased miR-106a inhibits glioma cell glucose uptake and proliferation by targeting SLC2A3 in GBM.

    Science.gov (United States)

    Dai, Dong-Wei; Lu, Qiong; Wang, Lai-Xing; Zhao, Wen-Yuan; Cao, Yi-Qun; Li, Ya-Nan; Han, Guo-Sheng; Liu, Jian-Min; Yue, Zhi-Jian

    2013-10-14

    MiR-106a is frequently down-regulated in various types of human cancer. However the underlying mechanism of miR-106a involved in glioma remains elusive. The association of miR-106a with glioma grade and patient survival was analyzed. The biological function and target of miR-106a were determined by bioinformatic analysis and cell experiments (Western blot, luciferase reporter, cell cycle, ntracellular ATP production and glucose uptake assay). Finally, rescue expression of its target SLC2A3 was used to test the role of SLC2A3 in miR-106a-mediated cell glycolysis and proliferation. Here we showed that miR-106a was a tumor suppressor miRNA was involved in GBM cell glucose uptake and proliferation. Decreased miR-106a in GBM tissues and conferred a poor survival of GBM patients. SLC2A3 was identified as a core target of miR-106a in GBM cells. Inhibition of SLC2A3 by miR-106a attenuated cell proliferation and inhibited glucose uptake. In addition, for each biological process we identified ontology-associated transcripts that significantly correlated with SLC2A3 expression. Finally, the expression of SLC2A3 largely abrogated miR-106a-mediated cell proliferation and glucose uptake in GBM cells. Taken together, miR-106a and SLC2A3 could be potential therapeutic approaches for GBM.

  14. Membrane Disruption Mechanism of a Prion Peptide (106-126) Investigated by Atomic Force Microscopy, Raman and Electron Paramagnetic Resonance Spectroscopy.

    Science.gov (United States)

    Pan, Jianjun; Sahoo, Prasana K; Dalzini, Annalisa; Hayati, Zahra; Aryal, Chinta M; Teng, Peng; Cai, Jianfeng; Rodriguez Gutierrez, Humberto; Song, Likai

    2017-05-18

    A fragment of the human prion protein spanning residues 106-126 (PrP106-126) recapitulates many essential properties of the disease-causing protein such as amyloidogenicity and cytotoxicity. PrP106-126 has an amphipathic characteristic that resembles many antimicrobial peptides (AMPs). Therefore, the toxic effect of PrP106-126 could arise from a direct association of monomeric peptides with the membrane matrix. Several experimental approaches are employed to scrutinize the impacts of monomeric PrP106-126 on model lipid membranes. Porous defects in planar bilayers are observed by using solution atomic force microscopy. Adding cholesterol does not impede defect formation. A force spectroscopy experiment shows that PrP106-126 reduces Young's modulus of planar lipid bilayers. We use Raman microspectroscopy to study the effect of PrP106-126 on lipid atomic vibrational dynamics. For phosphatidylcholine lipids, PrP106-126 disorders the intrachain conformation, while the interchain interaction is not altered; for phosphatidylethanolamine lipids, PrP106-126 increases the interchain interaction, while the intrachain conformational order remains similar. We explain the observed differences by considering different modes of peptide insertion. Finally, electron paramagnetic resonance spectroscopy shows that PrP106-126 progressively decreases the orientational order of lipid acyl chains in magnetically aligned bicelles. Together, our experimental data support the proposition that monomeric PrP106-126 can disrupt lipid membranes by using similar mechanisms found in AMPs.

  15. 9 CFR 201.108-1 - Instructions for weighing live poultry.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Instructions for weighing live poultry... STOCKYARDS ACT Poultry-Packers and Live Poultry Dealers § 201.108-1 Instructions for weighing live poultry. Live poultry dealers who operate scales on which live poultry is weighed for purposes of purchase, sale...

  16. Pre-Big Bang, fundamental Physics and noncyclic cosmologies. Possible alternatives to standard concepts and laws

    Science.gov (United States)

    Gonzalez-Mestres, L.

    2014-04-01

    Detailed analyses of WMAP and Planck data can have significant implications for noncyclic pre-Big Bang approaches incorporating a new fundamental scale beyond the Planck scale and, potentially, new ultimate constituents of matter with unconventional basic properties as compared to standard particles. Cosmic-ray experiments at the highest energies can also yield relevant information. Hopefully, future studies will be able to deal with alternatives: i) to standard physics for the structure of the physical vacuum, the nature of space-time, the validity of quantum field theory and conventional symmetries, the interpretation of string-like theories...; ii) to standard cosmology concerning the origin and evolution of our Universe, unconventional solutions to the cosmological constant problem, the validity of inflationary scenarios, the need for dark matter and dark energy... Lorentz-like symmetries for the properties of matter can then be naturally stable space-time configurations resulting from more general primordial scenarios that incorporate physics beyond the Planck scale and describe the formation and evolution of the physical vacuum. A possible answer to the question of the origin of half-integer spins can be provided by a primordial spinorial space-time with two complex coordinates instead of the conventional four real ones, leading to a really new cosmology. We discuss basic questions and phenomenological topics concerning noncyclic pre-Big Bang cosmologies and potentially related physics.

  17. Alternative Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    West, M.; Duckers, L.; Lockett, P.; Loughridge, B.; Peatfield, T.; White, P.

    1984-01-01

    The Coventry (Lanchester) Polytechnic Wave Energy Group has been involved in the United Kingdom wave energy research programme since its inception in 1975. Whilst the work of the group is mainly concerned with wave energy, and currently is directed towards the design of a wave energy device tailored to the needs of isolated/island communities, it has some involvement with other aspects of the alternatives. This conference, dealing with alternative energy systems and their electrical integration and utilisation was engendered by the general interest which the Polytechnic group members have in the alternatives and their use. The scope for electrical integration and utilisation is very broad. Energy for family groups may be provided in a relatively unsophisticated way which is acceptable to them. Small population centres, for example island communities relying upon diesel equipment, can reap the benefits of the alternatives through their ability to accept novel integration schemes and a flexible approach to the use of the energy available. Consumers already enjoying the benefits of a 'firm' electricity grid supply can use energy from a variety of alternative systems, via the grid, without having to modify their energy consumption habits. In addition to the domestic and industrial applications and coastal possibilities, specialist applications in isolated environments have also emerged. The Proceedings detail practical, technical and economic aspects of the alternatives and their electrical integration and utilisation.

  18. Outlook for alternative energy sources. [aviation fuels

    Science.gov (United States)

    Card, M. E.

    1980-01-01

    Predictions are made concerning the development of alternative energy sources in the light of the present national energy situation. Particular emphasis is given to the impact of alternative fuels development on aviation fuels. The future outlook for aircraft fuels is that for the near term, there possibly will be no major fuel changes, but minor specification changes may be possible if supplies decrease. In the midterm, a broad cut fuel may be used if current development efforts are successful. As synfuel production levels increase beyond the 1990's there may be some mixtures of petroleum-based and synfuel products with the possibility of some shale distillate and indirect coal liquefaction products near the year 2000.

  19. Estimations of expectedness and potential surprise in possibility theory

    Science.gov (United States)

    Prade, Henri; Yager, Ronald R.

    1992-01-01

    This note investigates how various ideas of 'expectedness' can be captured in the framework of possibility theory. Particularly, we are interested in trying to introduce estimates of the kind of lack of surprise expressed by people when saying 'I would not be surprised that...' before an event takes place, or by saying 'I knew it' after its realization. In possibility theory, a possibility distribution is supposed to model the relative levels of mutually exclusive alternatives in a set, or equivalently, the alternatives are assumed to be rank-ordered according to their level of possibility to take place. Four basic set-functions associated with a possibility distribution, including standard possibility and necessity measures, are discussed from the point of view of what they estimate when applied to potential events. Extensions of these estimates based on the notions of Q-projection or OWA operators are proposed when only significant parts of the possibility distribution are retained in the evaluation. The case of partially-known possibility distributions is also considered. Some potential applications are outlined.

  20. Preparation and photocatalytic property of potassium niobate K6Nb10.8O30

    International Nuclear Information System (INIS)

    Zhang Gaoke; Zou Xi; Gong Jie; He Fangsheng; Zhang Hao; Zhang Qiang; Liu Ying; Yang Xia; Hu Bo

    2006-01-01

    The TB-type potassium niobate K 6 Nb 10.8 O 30 was synthesized by a simple solid-state reaction method. Scanning electron microscope (SEM) and X-ray diffractometer (XRD) were used to characterize the structure of the photocatalyst. The photocatalyst K 6 Nb 10.8 O 30 shows high photocatalytic activity to photodegrade acid red G under UV irradiation. The influences of catalyst dosage, initial concentration of acid red G on the photocatalytic reaction were investigated. The kinetics of photocatalytic degradation of acid red G follows the first order kinetics

  1. Seal design alternatives study

    International Nuclear Information System (INIS)

    Van Sambeek, L.L.; Luo, D.D.; Lin, M.S.; Ostrowski, W.; Oyenuga, D.

    1993-06-01

    This report presents the results from a study of various sealing alternatives for the WIPP sealing system. Overall, the sealing system has the purpose of reducing to the extent possible the potential for fluids (either gas or liquid) from entering or leaving the repository. The sealing system is divided into three subsystems: drift and panel seals within the repository horizon, shaft seals in each of the four shafts, and borehole seals. Alternatives to the baseline configuration for the WIPP seal system design included evaluating different geometries and schedules for seal component installations and the use of different materials for seal components. Order-of-magnitude costs for the various alternatives were prepared as part of the study. Firm recommendations are not presented, but the advantages and disadvantages of the alternatives are discussed. Technical information deficiencies are identified and studies are outlined which can provide required information

  2. Iliotibial band autograft versus bone-patella-tendon-bone autograft, a possible alternative for ACL reconstruction

    DEFF Research Database (Denmark)

    Stensbirk, Frederik; Thorborg, Kristian; Konradsen, Lars

    2014-01-01

    PURPOSE: The long-term results after using the iliotibial band autograft (ITB) in anterior cruciate ligament (ACL) reconstruction are not fully known. If equal in quality to conventional methods, the ITB graft could be a useful alternative as a primary graft, in revision surgery or multi-ligament......PURPOSE: The long-term results after using the iliotibial band autograft (ITB) in anterior cruciate ligament (ACL) reconstruction are not fully known. If equal in quality to conventional methods, the ITB graft could be a useful alternative as a primary graft, in revision surgery or multi...

  3. Alternate two-dimensional quantum walk with a single-qubit coin

    International Nuclear Information System (INIS)

    Di Franco, C.; Busch, Th.; Mc Gettrick, M.; Machida, T.

    2011-01-01

    We have recently proposed a two-dimensional quantum walk where the requirement of a higher dimensionality of the coin space is substituted with the alternance of the directions in which the walker can move [C. Di Franco, M. Mc Gettrick, and Th. Busch, Phys. Rev. Lett. 106, 080502 (2011)]. For a particular initial state of the coin, this walk is able to perfectly reproduce the spatial probability distribution of the nonlocalized case of the Grover walk. Here, we present a more detailed proof of this equivalence. We also extend the analysis to other initial states in order to provide a more complete picture of our walk. We show that this scheme outperforms the Grover walk in the generation of x-y spatial entanglement for any initial condition, with the maximum entanglement obtained in the case of the particular aforementioned state. Finally, the equivalence is generalized to wider classes of quantum walks and a limit theorem for the alternate walk in this context is presented.

  4. 24 CFR 1000.108 - How is HUD approval obtained by a recipient for housing for non low-income Indian families and...

    Science.gov (United States)

    2010-04-01

    ... recipient for housing for non low-income Indian families and model activities? 1000.108 Section 1000.108... AMERICAN HOUSING ACTIVITIES Affordable Housing Activities § 1000.108 How is HUD approval obtained by a.... Assistance to non low-income Indian families must be in accordance with § 1000.110. Proposals may be...

  5. 47 CFR 19.735-106 - Interpretation and advisory service.

    Science.gov (United States)

    2010-10-01

    ... through the employee's supervisor to the General Counsel, who is the Commission's Designated Agency Ethics Official pursuant to the delegation of authority at 47 CFR 0.251(a). (b) At the time of an employee's... Section 19.735-106 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL EMPLOYEE RESPONSIBILITIES...

  6. 17 CFR 10.106 - Reconsideration; stay pending judicial review.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Reconsideration; stay pending... COMMISSION RULES OF PRACTICE Appeals to the Commission; Settlements § 10.106 Reconsideration; stay pending... operate to stay the effective date of the Commission's order. (b) Stay pending judicial appeal—(1...

  7. 33 CFR 106.255 - Security systems and equipment maintenance.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Security systems and equipment... Shelf (OCS) Facility Security Requirements § 106.255 Security systems and equipment maintenance. (a) Security systems and equipment must be in good working order and inspected, tested, calibrated, and...

  8. Project W-320, 241-C-106 sluicing: Civil/structural calculations. Volume 6

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, J.W.

    1998-07-24

    This supporting document has been prepared to make the FDNW calculations for Project W-320 readily retrievable. The purpose of this calculation is to conservatively estimate the weight of equipment and structures being added over Tank 241-C-106 as a result of Project W-320 and combine these weights with the estimated weights of existing structures and equipment as calculated in Attachment 1. The combined weights will be compared to the allowable live load limit to provide a preliminary assessment of loading conditions above Tank 241-C-106.

  9. Engineering Task Plan for Tank 241-C-106 contingency chiller definitive design

    International Nuclear Information System (INIS)

    Rensink, G.E.; Kriskovich, J.R.

    1995-01-01

    This document identifies the scope, cost, schedule and responsible organizations for completing a design of a contingency ventilation inlet air cooling system for Tank 241-C-106. The air cooling system, described in Rensink (1995), consists of a chiller, cooling coils, and supporting equipment that, when installed will be capable of assuring that the waste temperatures in Tank 241-C-106 are maintained within acceptable limits for safe storage. The effort described herein is scheduled for completion by May 31, 1995 to support Performance Based Incentive (PBI) Milestone SI-2x

  10. 108mAg and 110mAg in crassostrea gigas

    International Nuclear Information System (INIS)

    Ishikawa, Y.; Sato, N.; Nakamura, E.; Sekine, T.; Yoshihara, K.

    1992-01-01

    Accumulation of radiosilver 108m Ag and 110m Ag in oysters (Crassostrea gigas) and their behavior in marine environments has been studied in the northeast Pacific coast in Japan. Enrichment of radiosilver in oysters depends on topographical conditions; significant bioaccumulation occurred in open bays, while it was hardly observed in bays with narrow shaped entrances. From these observations difference of the behavior of radiosilver between open and nearly closed bays is suggested. 110m Ag in oysters decayed with an effective half-life of about 150 days for both the Chinese nuclear weapon test and the Chernobyl accident. In contrast to radiosilver, the fission product nuclide 137 Cs was almost independent of topographical conditions, and its concentration was constant. 110m Ag bioaccumulation in oysters after the Chernobyl accident in 1986 was found in both open and nearly closed bays, the lattershowing much lower concentration of radiosilver than the former. Specific activity of 108m Ag in oysters was determined in bays open to the Pacific Oceans. (author) 13 refs.; 4 figs.; 3 tabs

  11. Learn About the Water Pollution Control (Section 106) Grant Program

    Science.gov (United States)

    Under CWA Section 106, EPA is authorized to provide grants to states, eligible interstate agencies, and eligible tribes to establish and administer programs, including enforcement programs,for the prevention, reduction, and elimination of water pollution.

  12. Pesakastide jaoks jääb võimsust ülegi / Rakennusmaailma põhjal Ingrid Maasik

    Index Scriptorium Estoniae

    2011-01-01

    10,8- ja 12voldised akutrell-kruvikeerajad: AEG BS 12 C 2, Biltema 17-275, Black&Decker HPL106K, Bosch GSR 10,8-Li-2, DeWalt DCD710, Einhell BT-CD, Festool CXS, Festool C12Li, Hitachi DS 10 DFL, Makita DF330D, Metabo PowerMaxx 12, Milwaukee C12DD-32C, Nutool 10,8V, Panasonic EY6409

  13. 5 CFR 6701.106 - Prior approval for outside employment.

    Science.gov (United States)

    2010-01-01

    ... STANDARDS OF ETHICAL CONDUCT FOR EMPLOYEES OF THE GENERAL SERVICES ADMINISTRATION § 6701.106 Prior approval... to be performed; (4) The name and address of the prospective outside employer for which work will be... affects the outside employer and will disqualify himself from future participation in matters that could...

  14. 13 CFR 108.620 - Requirements to obtain information from Portfolio Concerns.

    Science.gov (United States)

    2010-01-01

    ... requirements of § 108.600 and must be in English. (a) Information for initial Financing decision. Before extending any Financing, you must require the applicant to submit such financial statements, plans of operation (including intended use of financing proceeds), cash flow analyses, projections, and such...

  15. Structure of dipole bands in 106In

    International Nuclear Information System (INIS)

    Deo, A. Y.; Palit, R.; Naik, Z.; Joshi, P. K.; Mazumdar, I.; Sihotra, S.; Mehta, D.; Kumar, S.; Chakrabarti, R.; Kshetri, R.; Jain, H. C.

    2009-01-01

    High spin states in neutron-deficient 106 In were investigated using 78 Se( 32 S,p3n) reaction at 125 MeV. The level scheme is extended up to 7 MeV of excitation energy for the negative parity states constituting four dipole bands, and the positive parity states which mainly exhibit single-particle excitations are extended up to 5 MeV. Projected deformed Hartree-Fock calculations were carried out to understand the configurations of different bands in this nucleus.

  16. Small stress molecules inhibit aggregation and neurotoxicity of prion peptide 106-126

    International Nuclear Information System (INIS)

    Kanapathipillai, Mathumai; Ku, Sook Hee; Girigoswami, Koyeli; Park, Chan Beum

    2008-01-01

    In prion diseases, the posttranslational modification of host-encoded prion protein PrP c yields a high β-sheet content modified protein PrP sc , which further polymerizes into amyloid fibrils. PrP106-126 initiates the conformational changes leading to the conversion of PrP c to PrP sc . Molecules that can defunctionalize such peptides can serve as a potential tool in combating prion diseases. In microorganisms during stressed conditions, small stress molecules (SSMs) are formed to prevent protein denaturation and maintain protein stability and function. The effect of such SSMs on PrP106-126 amyloid formation is explored in the present study using turbidity, atomic force microscopy (AFM), and cellular toxicity assay. Turbidity and AFM studies clearly depict that the SSMs-ectoine and mannosylglyceramide (MGA) inhibit the PrP106-126 aggregation. Our study also connotes that ectoine and MGA offer strong resistance to prion peptide-induced toxicity in human neuroblastoma cells, concluding that such molecules can be potential inhibitors of prion aggregation and toxicity

  17. Integrating Exposure into Chemical Alternatives Assessment Using a Qualitative Approach

    Science.gov (United States)

    Most alternatives assessments (AA) published to date are largely hazard-based rankings, and as such may not represent a fully informed consideration of the advantages and disadvantages of possible alternatives. With an assessment goal of identifying an alternative chemical that i...

  18. South African Medical Journal - Vol 106, No 4 (2016)

    African Journals Online (AJOL)

    A multifaceted hospital-wide intervention increases hand hygiene compliance · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. B Patel, H Engelbrecht, H McDonald, V Morris, W Smythe, 335-341. http://dx.doi.org/10.7196/SAMJ.2016.v106i4.10671 ...

  19. 23 CFR 635.106 - Use of publicly owned equipment.

    Science.gov (United States)

    2010-04-01

    ... CONSTRUCTION AND MAINTENANCE Contract Procedures § 635.106 Use of publicly owned equipment. (a) Publicly owned equipment should not normally compete with privately owned equipment on a project to be let to contract... publicly owned equipment is to be made available in connection with construction work to be let to contract...

  20. 46 CFR 108.550 - Survival craft launching and recovery arrangements: General.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft launching and recovery arrangements...-MOBILE OFFSHORE DRILLING UNITS DESIGN AND EQUIPMENT Lifesaving Equipment § 108.550 Survival craft.... (c) Each survival craft must be arranged to clear each leg, column, footing, brace, mat, and each...

  1. El medio interestelar alrededor de estrellas Of: HD 108

    Science.gov (United States)

    Cappa, C.; Testori, J. C.

    Hemos analizado la distribución del hidrógeno neutro interestelar en la vecindad de la estrella Of HD 108 en base a perfiles de la línea de 21 cm. Estos datos nos han permitido encontrar una probable burbuja interestelar asociada a la estrella. Comparamos estos resultados con la emisión en otros rangos espectrales y estimamos los principales parámetros físicos de la estructura.

  2. Tank characterization report for single-shell tank 241-T-106

    International Nuclear Information System (INIS)

    Jo, J.

    1996-03-01

    This document summarizes the information on the historical uses, present status, and the sampling and analysis results of waste stored in Tank 241-T-106. This report supports the requirements of Tri-Party Agreement Milestone M-44-09

  3. Dose patterns for 106RuO4 inhaled by Fischer-344 rats and Beagle dogs

    International Nuclear Information System (INIS)

    Runkle, G.E.; Snipes, M.B.

    1978-01-01

    Ruthenium-106 is an abundant fission product radionuclide in the nuclear fuel cycle which has potential for release as ruthenium tetroxide. Ruthenium tetroxide is a vapor, diffuses rapidly through air and porous materials, is chemically reactive and is rapidly reduced by any organic material to the dioxide form. Current ICRP recommendations consider the lung and gastrointestinal tract as critical organs for inhaled particles of radioactive ruthenium. This study was designed to provide additional data needed to adequately assess the risk for humans potentially exposed to 106 Ru encountered in this vapor form. Fischer-344 rats and Beagle dogs were given a nose-only exposure to 106 RuO 4 vapor to determine its distribution and retention patterns. The largest percentage of the initial body burden was found in the nasopharyngeal region of the respiratory tract. Less than 1% of the initial body burden was deposited in the pulmonary region. Most of the 106 Ru was cleared via the feces. A biomathematical simulation model was developed to fit the tissue and excreta data from the rat. This model was used to assess the short-term and long-term risks after inhalation of 106 RuO 4 . The observed deposition, retention and dose patterns for ruthenium tetroxide indicate the nasopharyngeal region should be considered as a critical region when considering the consequences of human exposure to this vapor

  4. Safety evaluation for packaging transportation of equipment for tank 241-C-106 waste sluicing system

    International Nuclear Information System (INIS)

    Calmus, D.B.

    1994-01-01

    A Waste Sluicing System (WSS) is scheduled for installation in nd waste storage tank 241-C-106 (106-C). The WSS will transfer high rating sludge from single shell tank 106-C to double shell waste tank 241-AY-102 (102-AY). Prior to installation of the WSS, a heel pump and a transfer pump will be removed from tank 106-C and an agitator pump will be removed from tank 102-AY. Special flexible receivers will be used to contain the pumps during removal from the tanks. After equipment removal, the flexible receivers will be placed in separate containers (packagings). The packaging and contents (packages) will be transferred from the Tank Farms to the Central Waste Complex (CWC) for interim storage and then to T Plant for evaluation and processing for final disposition. Two sizes of packagings will be provided for transferring the equipment from the Tank Farms to the interim storage facility. The packagings will be designated as the WSSP-1 and WSSP-2 packagings throughout the remainder of this Safety Evaluation for Packaging (SEP). The WSSP-1 packagings will transport the heel and transfer pumps from 106-C and the WSSP-2 packaging will transport the agitator pump from 102-AY. The WSSP-1 and WSSP-2 packagings are similar except for the length

  5. Alternative possibilities of development in the power economy of the FRG

    International Nuclear Information System (INIS)

    Rath-Nagel, S.

    1975-06-01

    In the investigation presented here, problem areas of the energy supply as reserves, reliability of supply, environmental pollution and investment and financial questions are discussed. The author tries to represent quantitatively the boundary conditions of our energy supply system and the cause-effect relations determining the energy market. For the Federal Republic of Germany a simulation model consisting of coupled differential equations is developed, which is able to demonstrate the variations of the energy economic structure of supply and demand under various external conditions. There is in particular a close analysis of the strength of feedback between energy consumption and economic growth, the effects of various modes of supply under abnormal conditions and of realizable alternative supply patterns during the investigatory period. (orig.) [de

  6. Tank 241-BY-106 vapor sampling and analysis tank characterization report. Revision 1

    International Nuclear Information System (INIS)

    Huckaby, J.L.

    1995-01-01

    Tank 241-BY-106 headspace gas and vapor samples were collected and analyzed to help determine the potential risks to tank farm workers due to fugitive emissions from the tank. The drivers and objectives of waste tank headspace sampling and analysis are discussed in open-quotes Program Plan for the Resolution of Tank Vapor Issues.close quotes Tank 241-BY-106 was vapor sampled in accordance with open-quotes Data Quality Objectives for Generic In-Tank Health and Safety Issue Resolution.close quotes

  7. 13 CFR 106.302 - What provisions must be set forth in a Fee Based Record?

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What provisions must be set forth in a Fee Based Record? 106.302 Section 106.302 Business Credit and Assistance SMALL BUSINESS... does not constitute or imply an endorsement by SBA of the Donor or the Donor's products or services. ...

  8. 9 CFR 108.6 - Revision of plot plans, blueprints, and legends.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Revision of plot plans, blueprints... FACILITY REQUIREMENTS FOR LICENSED ESTABLISHMENTS § 108.6 Revision of plot plans, blueprints, and legends... changes affecting the workflow are to be made. The licensee shall: (a) Prepare revised plot plans...

  9. 48 CFR 49.108-5 - Recognition of judgments and arbitration awards.

    Science.gov (United States)

    2010-10-01

    ... ACQUISITION REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS General Principles 49.108-5 Recognition of... arbitration under any applicable law or contract provision, the TCO shall recognize the arbitration award as... contractor, the TCO shall, for the purposes of settling the prime contract, treat the amount of the judgment...

  10. Sampling and Analysis Plan for Tank 241-AP-108 Waste in Support of Evaporator Campaign 2000-1

    International Nuclear Information System (INIS)

    RASMUSSEN, J.H.

    2000-01-01

    This Tank Sampling and Analysis Plan (TSAP) identifies sample collection, laboratory analysis, quality assurance/quality control (QA/QC), and reporting objectives for the characterization of tank 241-AP-108 waste. Technical bases for these objectives are specified in the 242-A Evaporator Data Quality Objectives (Bowman 2000 and Von Bargen 1998) and 108-AP Tank Sampling Requirements in Support of Evaporator Campaign 2000-1 (Le 2000). Evaporator campaign 2000-1 will process waste from tank 241-AP-108 in addition to that from tank 241-AP-107. Characterization results will be used to support the evaporator campaign currently planned for early fiscal year 2000. No other needs (or issues) requiring data for this tank waste apply to this sampling event

  11. First aqueous chemistry with Seaborgium (element 106)

    International Nuclear Information System (INIS)

    Schaedel, M.; Bruechle, W.; Schausten, B.; Schimpf, E.; Jaeger, E.; Wirth, G.; Guenther, R.; Gregorich, K.E.; Hoffman, D.C.; Lee, D.M.; Sylwester, E.R.; Nagame, Y.; Oura, Y.

    1996-11-01

    For the first time, chemical separations of element 106 (Seaborgium, Sg) were performed in aqueous solutions. The isotopes 265 Sg and 266 Sg were produced in the 248 Cm+ 22 Ne reaction at a beam energy of 121 MeV. The reaction products were continuously transported by a He(KCl)-jet to the computer-controlled liquid chromatography system ARCA. In 0.1 M HNO 3 /5 x 10 -4 M HF, Sg was found to be eluted within 10 s from 1.6 x 8 mm cation-exchange columns (Aminex A6, 17.5±2 μm) together with the hexavalent Mo- and W-ions, while hexavalent U-ions and tetravalent Zr-, Hf-, and element 104 ions were strongly retained on the column. Element 106 was detected by measuring correlated α-decays of the daughter isotopes 78-s 261 104 and 26-s 257 102. For the isotope 266 Sg, we have evidence for a spontaneous fission branch. It yields a partial spontaneous-fission half-life which is in agreement with recent theoretical predictions. The chemical results show that the most stable oxidation state of Sg in aqueous solution is +6, and that like its homologs Mo and W, Sg forms neutral or anionic oxo- or oxohalide-compounds under the present condition. In these first experiments, Sg exhibits properties very characteristic of group 6 elements, and does not show U-like properties. (orig.)

  12. Voltage-gated sodium channel expression and action potential generation in differentiated NG108-15 cells.

    Science.gov (United States)

    Liu, Jinxu; Tu, Huiyin; Zhang, Dongze; Zheng, Hong; Li, Yu-Long

    2012-10-25

    The generation of action potential is required for stimulus-evoked neurotransmitter release in most neurons. Although various voltage-gated ion channels are involved in action potential production, the initiation of the action potential is mainly mediated by voltage-gated Na+ channels. In the present study, differentiation-induced changes of mRNA and protein expression of Na+ channels, Na+ currents, and cell membrane excitability were investigated in NG108-15 cells. Whole-cell patch-clamp results showed that differentiation (9 days) didn't change cell membrane excitability, compared to undifferentiated state. But differentiation (21 days) induced the action potential generation in 45.5% of NG108-15 cells (25/55 cells). In 9-day-differentiated cells, Na+ currents were mildly increased, which was also found in 21-day differentiated cells without action potential. In 21-day differentiated cells with action potential, Na+ currents were significantly enhanced. Western blot data showed that the expression of Na+ channels was increased with differentiated-time dependent manner. Single-cell real-time PCR data demonstrated that the expression of Na+ channel mRNA was increased by 21 days of differentiation in NG108-15 cells. More importantly, the mRNA level of Na+ channels in cells with action potential was higher than that in cells without action potential. Differentiation induces expression of voltage-gated Na+ channels and action potential generation in NG108-15 cells. A high level of the Na+ channel density is required for differentiation-triggered action potential generation.

  13. 9 CFR 108.7 - Filing of plot plans, blueprints, and legends.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Filing of plot plans, blueprints, and... REQUIREMENTS FOR LICENSED ESTABLISHMENTS § 108.7 Filing of plot plans, blueprints, and legends. Three copies of all plot plans, blueprints, and legends, including revisions, shall be submitted to Animal and Plant...

  14. 13 CFR 108.800 - Financings in the form of equity interests.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Financings in the form of equity... VENTURE CAPITAL (âNMVCâ) PROGRAM Financing of Small Businesses by NMVC Companies Structuring Nmvc Company's Financing of Eligible Small Businesses § 108.800 Financings in the form of equity interests. You...

  15. Alternatives to the Dirac equation

    International Nuclear Information System (INIS)

    Girvin, S.M.; Brownstein, K.R.

    1975-01-01

    Recent work by Biedenharn, Han, and van Dam (BHvD) has questioned the uniqueness of the Dirac equation. BHvD have obtained a two-component equation as an alternate to the Dirac equation. Although they later show their alternative to be unitarily equivalent to the Dirac equation, certain physical differences were claimed. BHvD attribute the existence of this alternate equation to the fact that their factorizing matrices were position-dependent. To investigate this, we factor the Klein-Gordon equation in spherical coordinates allowing the factorizing matrices to depend arbitrarily upon theta and phi. It is shown that despite this additional freedom, and without involving any relativistic covariance, the conventional four-component Dirac equation is the only possibility

  16. 5 CFR 5501.108 - Exception to the prohibition against assisting in the prosecution of claims against, or acting as...

    Science.gov (United States)

    2010-01-01

    ... regional or village corporations pursuant to the Intergovernmental Personnel Act. 5501.108 Section 5501.108... regional or village corporations pursuant to the Intergovernmental Personnel Act. (a) 18 U.S.C. 205... villages or regional or village corporations pursuant to the Intergovernmental Personnel Act...

  17. Influenza A virus NS1 gene mutations F103L and M106I increase replication and virulence

    Directory of Open Access Journals (Sweden)

    Ping Jihui

    2011-01-01

    Full Text Available Abstract Background To understand the evolutionary steps required for a virus to become virulent in a new host, a human influenza A virus (IAV, A/Hong Kong/1/68(H3N2 (HK-wt, was adapted to increased virulence in the mouse. Among eleven mutations selected in the NS1 gene, two mutations F103L and M106I had been previously detected in the highly virulent human H5N1 isolate, A/HK/156/97, suggesting a role for these mutations in virulence in mice and humans. Results To determine the selective advantage of these mutations, reverse genetics was used to rescue viruses containing each of the NS1 mouse adapted mutations into viruses possessing the HK-wt NS1 gene on the A/PR/8/34 genetic backbone. Both F103L and M106I NS1 mutations significantly enhanced growth in vitro (mouse and canine cells and in vivo (BALB/c mouse lungs as well as enhanced virulence in the mouse. Only the M106I NS1 mutation enhanced growth in human cells. Furthermore, these NS1 mutations enhanced early viral protein synthesis in MDCK cells and showed an increased ability to replicate in mouse interferon β (IFN-β pre-treated mouse cells relative to rPR8-HK-NS-wt NS1. The double mutant, rPR8-HK-NS-F103L + M106I, demonstrated growth attenuation late in infection due to increased IFN-β induction in mouse cells. We then generated a rPR8 virus possessing the A/HK/156/97 NS gene that possesses 103L + 106I, and then rescued the L103F + I106M mutant. The 103L + 106I mutations increased virulence by >10 fold in BALB/c mice. We also inserted the avian A/Ck/Beijing/1/95 NS1 gene (the source lineage of the A/HK/156/97 NS1 gene that possesses 103L + 106I, onto the A/WSN/33 backbone and then generated the L103F + I106M mutant. None of the H5N1 and H9N2 NS containing viruses resulted in increased IFN-β induction. The rWSN-A/Ck/Beijing/1/95-NS1 gene possessing 103L and 106I demonstrated 100 fold enhanced growth and >10 fold enhanced virulence that was associated with increased tropism for lung

  18. 29 CFR 780.106 - Employment in “primary” agriculture is farming regardless of why or where work is performed.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Employment in âprimaryâ agriculture is farming regardless of why or where work is performed. 780.106 Section 780.106 Labor Regulations Relating to Labor... for âprimaryâ Agriculture Generally § 780.106 Employment in “primary” agriculture is farming...

  19. Can scientific medicine incorporate alternative medicine?

    Science.gov (United States)

    Federspil, G; Vettor, R

    2000-06-01

    The authors examine the problem of defining alternative medicine, and after a brief analysis conclude that a satisfactory unifying definition of the different practices is not possible. Scientific knowledge is a function of scientific method. In turn the principle of falsifiability proposed by Karl Popper is used as a demarcation line between science and pseudoscience. They assert that the various alternative modalities do not represent authentic scientific disciplines, as they lack many of the minimum requirements of scientific discourse and, above all, because they violate the principle of falsifiability. Until they overcome these methodological shortcomings, alternative medical practices cannot become authentic scientific disciplines.

  20. K2-106, a system containing a metal-rich planet and a planet of lower density

    Science.gov (United States)

    Guenther, E. W.; Barragán, O.; Dai, F.; Gandolfi, D.; Hirano, T.; Fridlund, M.; Fossati, L.; Chau, A.; Helled, R.; Korth, J.; Prieto-Arranz, J.; Nespral, D.; Antoniciello, G.; Deeg, H.; Hjorth, M.; Grziwa, S.; Albrecht, S.; Hatzes, A. P.; Rauer, H.; Csizmadia, Sz.; Smith, A. M. S.; Cabrera, J.; Narita, N.; Arriagada, P.; Burt, J.; Butler, R. P.; Cochran, W. D.; Crane, J. D.; Eigmüller, Ph.; Erikson, A.; Johnson, J. A.; Kiilerich, A.; Kubyshkina, D.; Palle, E.; Persson, C. M.; Pätzold, M.; Sabotta, S.; Sato, B.; Shectman, St. A.; Teske, J. K.; Thompson, I. B.; Van Eylen, V.; Nowak, G.; Vanderburg, A.; Winn, J. N.; Wittenmyer, R. A.

    2017-12-01

    Aims: Planets in the mass range from 2 to 15 M⊕ are very diverse. Some of them have low densities, while others are very dense. By measuring the masses and radii, the mean densities, structure, and composition of the planets are constrained. These parameters also give us important information about their formation and evolution, and about possible processes for atmospheric loss. Methods: We determined the masses, radii, and mean densities for the two transiting planets orbiting K2-106. The inner planet has an ultra-short period of 0.57 days. The period of the outer planet is 13.3 days. Results: Although the two planets have similar masses, their densities are very different. For K2-106b we derive Mb=8.36-0.94+0.96 M⊕, Rb = 1.52 ± 0.16 R⊕, and a high density of 13.1-3.6+5.4 g cm-3. For K2-106c, we find Mc=5.8-3.0+3.3 M⊕, Rc=2.50-0.26+0.27 R⊕ and a relatively low density of 2.0-1.1+1.6 g cm-3. Conclusions: Since the system contains two planets of almost the same mass, but different distances from the host star, it is an excellent laboratory to study atmospheric escape. In agreement with the theory of atmospheric-loss processes, it is likely that the outer planet has a hydrogen-dominated atmosphere. The mass and radius of the inner planet is in agreement with theoretical models predicting an iron core containing 80-30+20% of its mass. Such a high metal content is surprising, particularly given that the star has an ordinary (solar) metal abundance. We discuss various possible formation scenarios for this unusual planet. The results are partly based on observations obtained at the European Southern Observatory at Paranal, Chile in program 098.C-0860(A). This paper includes data gathered with the 6.5 m Magellan Telescopes located at Las Campanas Observatory, Chile. The article is also partly based on observations with the TNG, NOT. This work has also made use of data from the European Space Agency (ESA) mission Gaia (http

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