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Sample records for positive mini diagnosis

  1. [Comparison of endotracheal aspiration and mini-BAL culture results in the diagnosis of ventilator-associated pneumonia].

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    Artuk, Cumhur; Gül, Hanefi Cem; Mert, Gürkan; Karakaş, Ahmet; Bedir, Orhan; Eyigün, Can Polat

    2012-07-01

    The objective of this study was to compare the results of cultures obtained by mini-bronchoalveolar lavage (BAL) and endotracheal aspiration (ETA) techniques, used for rapid and accurate determination of pathogens causing ventilator-associated pneumonia (VAP) in intensive care units. Of the 92 patients on mechanical ventilation followed at the emergency intensive care unit of our hospital between June 2010 and June 2011, 30 (32.2%) patients were diagnosed as VAP and they were included in this study. VAP diagnosis were based on the clinical and radiological findings. Clinical pulmonary infection score (CPIS) of > 6 was accepted as the clinical criteria of VAP. Initially ETA samples were collected from the patients followed by mini-BAL sampling 15 minutes later, together with urine and two blood cultures. Microbiological evaluation and identification were performed by conventional methods and Phoenix 100 (BD Diagnostic Systems, ABD) automated system. In quantitative culture analysis, > 10.000 cfu/ml for BAL and > 100.000 cfu/ml for ETA were accepted as the positive result. The mean ages of VAP-developed (n= 30; 18 were male) and nondeveloped (n= 62; 39 were male) patients were 68.23 ± 16.19 and 52.16 ± 10.41 years, respectively, and the mean durations of mechanical ventilation were 29.57 ± 15.78 and 12.11 ± 6.01 days, respectively. Multivariate logistic regression analysis showed that older age (pVAP development. There was also a statistically significant difference in CPIS values between patients who developed VAP and not (6.8 ± 1.15 and 2.71 ± 1.06, respectively; pVAP diagnosis was found to be useful in patients on mechanical ventilation. In our study, a total of 16 strains (six A.baumannii, three P.aeruginosa, one K.pneumoniae, six S.aureus) were isolated from ETA cultures, while 34 strains (16 A.baumannii, six P.aeruginosa, four K.pneumoniae, two E.coli, six S.aureus) were isolated from mini-BAL cultures of 30 VAP patients. The contamination rate for ETA

  2. [Reliability and validity of the standardized Mini Mental State Examination in the diagnosis of mild dementia in Turkish population].

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    Güngen, Can; Ertan, Turan; Eker, Engin; Yaşar, Resmiye; Engin, Funda

    2002-01-01

    Reliability and validity of the Mini Mental State Examination in differentiating mild dementia from normal controls in Turkish population. The Standardized Mini Mental State Examination (SMMSE) and its instruction were translated into Turkish. A total of 212 subjects with mean age of 77 +/- 6, were recruited for the study. 71 were diagnosed to be demented and 141 were evaluated as normal controls. The scale total score was analysed for discriminant validity using Student's t-test. Sensitivity, specificity, positive and negative predictive values and kappa score were calculated for all of the scores between 18 and 29. Kappa value was calculated for the comparison of the dementia diagnosis between the two investigators using the best cut off score obtained in the analysis above. Statistical analysis revealed that the Turkish version of the SMMSE has high discriminant validity and interrater reliability in the diagnosis of mild dementia. The cut off score 23/24 was found to have the highest sensitivity (0.91), specificity (0.95), positive and negative predictive values (0.90 and 0.95) and kappa score (0.86). Interrater reliability analysis showed high correlation (r:0.99) and kappa value (0.92). The results of this study showed that the Turkish version of the SMMSE has high reliability and validity for the diagnosis of mild dementia in Turkish population.

  3. DIAGNOSIS OF FINANCIAL POSITION STRUCTURE

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    CĂRUNTU GENU ALEXANDRU

    2017-02-01

    Full Text Available The analysis of financial position structure aimed at issues that highlight on the one hand the economic relations between asset side and liability side and on the other hand the changes that are achieved as a result of internal and external factors. In order to establish the causes that led over time to changing the structure of financial position we analyze the structure of assets, liabilities and equity. The balance sheet is a summary representing only a snapshot at a certain time that changes continuously and through which are presented economic goods, rights and obligations of the company at year-end. The balance sheet is the universal working tool that contains information on the company's heritage and performance. To achieve its purpose, namely to generate profit in conditions of intense competition the firm constitutes a heritage structure, an economic fixed and circulating capital appropriate to future needs.

  4. Mini-hydropower development in human province of China and its position in the national economy

    International Nuclear Information System (INIS)

    Daogao, L.

    1991-01-01

    Hunan province is situated in the southern part of the middle reaches of Yangtze River. With a population of 61 million, it covers an area of about 211,800 km 2 , equivalent to forty percents of the territorial area of France. Throughout the province, there are more than 5300 rivers and 13000 reservoirs completed before 1991, of which over 7300 mini-hydropower stations are under operation. The theoretical hydropower potential is 15320 MW among them 12990 MW can be exploited with a total installed capacity of 1320 MW and an annual generation output of 4150 GWh. The paper will describe the general condition of the hydropower resources, development of mini-hydropower in Human province and its positive role in the national economy. Additionally, the standard of classification, the type of equipment for the medium and small-sized hydropower plants and market conditions in Hunan will be also involved in the paper. 5 tabs

  5. Maxillary anterior en masse retraction using different antero-posterior position of mini screw: a 3D finite element study

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    Zohreh Hedayati

    2016-10-01

    Full Text Available Abstract Background Nowadays, mini screws are used in orthodontic tooth movement to obtain maximum or absolute anchorage. They have gained popularity among orthodontists for en masse retraction of anterior teeth after first premolar extraction in maximum anchorage cases. The purpose of this study was to determine the type of anterior tooth movement during the time when force was applied from different mini screw placements to the anterior power arm with various heights. Methods A finite element method was used for modeling maxillary teeth and bone structure. Brackets, wire, and hooks were also designed for modeling. Two appropriate positions for mini screw in the mesial and distal of the second premolar were designed as fixed nodes. Forces were applied from the mini screw to four different levels of anterior hook height: 0, 3, 6, and 9 mm. Initial tooth movement in eight different conditions was analyzed and calculated with ANSYS software. Results Rotation of anterior dentition was decreased with a longer anterior power arm and the mesial placement of the mini screw. Bodily movements occurred with the 9-mm height of the power arm in both mini screw positions. Intrusion or extrusion of the anterior teeth segment depended on the level of the mini screw and the edge of the power arm on the Z axis. Conclusions According to the findings of this study, the best control in the sagittal plane during anterior en masse retraction was achieved by mesial placement of the mini screw and the 9-mm height of the anterior power arm. Where control in the vertical plane was concerned, distal placement of the mini screw with the 6-mm power arm height had minimum adverse effect on anterior dentition.

  6. [Positioning diagnosis of benign positional paroxysmal vertigo by VNG].

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    Wang, Na; Chen, Taisheng; Lin, Peng; Song, Wei; Dong, Hong

    2009-07-01

    To analyze the value of positioning diagnosis of VNG (Videonystagmograph) in patients with benign paroxysmal positional vertigo (BPPV). One hundred and twenty-six patients with BPPV were enrolled in this retrospective study. Their positional nystagmus recorded by VNG in Dix-Hallpike and roll tests were analyzed to summarize the characteristics of nystagmus on nystagmography of various BPPV. Of 126 patients with BPPV diagnosed in our center, the posterior semicircular canals (PSC) were involved in 98 patients (77.8%), whereas the horizontal semicircular canal (HSC) and anterior semicircular canal (ASC) were involved in 17 (13.5%) and 5 (3.9%), respectively. Six patients (4.8%) confirmed combined-BPPV had HSC-BPPV and ipsilateral PSC-BPPV. Twenty-eight patients with PSC-BPPV had reversal phase on nystagmography. The nystagmus of patients with P/ASC-canalithiasis showed upward/downward on the vertical phase of nystagmography and orientated the opposite side on horizontal phase in the head hanging position, and the nystagmus reversed when returned to sit. Nystagmus on horizontal phase could be provoked when the head turned to both sides of the roll tests in patients with HSC-BPPV. If the nystagmus and the head-turning shared the same direction, then HSC-canalithiasis was confirmed, and the direction of the head-turning which provoked the stronger nystagmus indicates the lesion side. If the nystagmus and the head-turning had the opposite direction, then HSC-cupulolithiasis was confirmed, and the direction of the head-turning which provoked the weaker nystagmus indicates the lesion side. Positional nystagmus can be recorded objectively using VNG, According to which positioning the semicircular canal involved would be easier and more accurate. The recording conserved also could be helpful for clinical diagnosis and repositioning of BPPV.

  7. Surgical positioning of orthodontic mini-implants with guides fabricated on models replicated with cone-beam computed tomography.

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    Kim, Seong-Hun; Choi, Yong-Suk; Hwang, Eui-Hwan; Chung, Kyu-Rhim; Kook, Yoon-Ah; Nelson, Gerald

    2007-04-01

    This article illustrates a new surgical guide system that uses cone-beam computed tomography (CBCT) images to replicate dental models; surgical guides for the proper positioning of orthodontic mini-implants were fabricated on the replicas, and the guides were used for precise placement. The indications, efficacy, and possible complications of this method are discussed. Patients who were planning to have orthodontic mini-implant treatment were recruited for this study. A CBCT system (PSR 9000N, Asahi Roentgen, Kyoto, Japan) was used to acquire virtual slices of the posterior maxilla that were 0.1 to 0.15 mm thick. Color 3-dimensional rapid prototyping was used to differentiate teeth, alveolus, and maxillary sinus wall. A surgical guide for the mini-implant was fabricated on the replica model. Proper positioning for mini-implants on the posterior maxilla was determined by viewing the CBCT images. The surgical guide was placed on the clinical site, and it allowed precise pilot drilling and accurate placement of the mini-implant. CBCT imaging allows remarkably lower radiation doses and thinner acquisition slices compared with medical computed tomography. Virtually reproduced replica models enable precise planning for mini-implant positions in anatomically complex sites.

  8. Validity of a short clinical interview for psychiatric diagnosis : the mini-SCAN

    NARCIS (Netherlands)

    Nienhuis, F. J.; van de Willige, G.; Rijnders, C. A. Th.; de Jonge, P.; Wiersma, D.

    Background To promote clinical application of the Schedules for Clinical Assessment in Neuropsychiatry (SCAN) system a shorter version (the mini-SCAN) was devised. Its psychometric properties were unknown. Aims To establish the validity and practical properties of the mini-SCAN. Method One hundred

  9. Supine or prone position for mini-PNL procedure: does it matter.

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    Tokatlı, Zafer; Gokce, Mehmet Ilker; Süer, Evren; Sağlam, Remzi

    2015-06-01

    In this study it is aimed to compare the success and complication rates of mini-PNL procedure in supine and prone positions. In this retrospective study data of 180 patients treated with MPNL either in supine (n = 54) or prone (n = 126) positions between May 2009 and August 2014 was investigated. Success was defined as no visible stones >2 mm. Perioperative complications were classified using the modified Clavien system. Groups were compared with Chi square test or Student t test and for statistical significance p value of 0.05 was accepted. Mean age of the population was 42.5 ± 8.2 years and mean stone size was 23.9 ± 4.1 mm. The two groups were similar with regard to demographic characteristics and stone related characteristics except the ASA status. Success rates of the supine and prone groups were 85.1 and 87.3%, respectively (p = 0.701). No statistically significant differences in terms of complications were observed. Mean operative time was the only parameter different between the two groups (55 vs 82 min, p = 0.001). Supine position for PNL seems to be promising and the complication and success rates are shown to be similar to the prone position with MPNL technique. The only significant benefit of this technique is shorter operative time.

  10. Validity of a short clinical interview for psychiatric diagnosis: the mini-SCAN.

    Science.gov (United States)

    Nienhuis, F J; van de Willige, G; Rijnders, C A Th; de Jonge, P; Wiersma, D

    2010-01-01

    To promote clinical application of the Schedules for Clinical Assessment in Neuropsychiatry (SCAN) system a shorter version (the mini-SCAN) was devised. Its psychometric properties were unknown. To establish the validity and practical properties of the mini-SCAN. One hundred and six participants were interviewed twice, once with the SCAN and once with the mini-SCAN. The level of agreement was established for the categories: no disorder, affective disorders, anxiety disorders, non-affective psychotic disorders, affective psychotic disorders. The mini-SCAN is a valid instrument. Most kappa values were around 0.90. Only for the class of affective psychotic disorders was the agreement moderate. Mean duration of the mini-SCAN interviews was 25 min shorter than the SCAN interviews. Participants and interviewers were generally satisfied with the interview format and questions. The mini-SCAN can be used as a diagnostic instrument for clinical purposes and for clinical studies when the present episode is the focus of attention.

  11. [Mini-Mental State Examination: Screening and Diagnosis of Cognitive Decline, Using New Normative Data].

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    Santana, Isabel; Duro, Diana; Lemos, Raquel; Costa, Vanessa; Pereira, Miguel; Simões, Mário R; Freitas, Sandra

    2016-04-01

    The Mini-Mental State Examination is the most commonly used cognitive screening test. In Portugal, the cut-off scores are defined according to literacy groups, but different proposals have been recommended by more representative studies. We therefore propose to confirm the influence of demographical variables, such as age and education, in the subjectâs performance; evaluating the discriminant ability of the new normative data; and to further examine the diagnostic acuity of the validated cut-off scoring for mild cognitive impairment and for the most prevalent types of dementia. Our study includes 1 441 educated subjects, divided into seven subgroups: Mild cognitive impairment, Alzheimer's disease, frontotemporal dementia, vascular dementia, dementia with Lewy bodies, community-controls and memory clinic-controls. Altogether age and education explain 10.4% of the Mini-Mental State Examination results variance, with both variables contributing significantly to the resultsâ prediction. The diagnostic acuity based on the most recent normative data was always higher than the one obtained through the validation cut-off scoring, revealing an overall excellent specificity (superior to 90%) and different sensitivity values: excellent for mild Alzheimer's disease (91%), good for dementia with Lewy Bodies (78%) and low for mild cognitive impairment (65%), frontotemporal dementia and vascular dementia (55%). The performance on the Mini-Mental State Examination is influenced by age and education, supporting the use of normative data that consider those variables. With this approach, the Mini-Mental State Examination could be a sensitive and specific instrument for the Alzheimer's disease screening among all healthcare levels. Nevertheless, its diagnostic acuity is limited in other conditions frequently seen in memory clinics, such as Mild Cognitive Impairment and other types of dementia.

  12. A positive diagnosis of functional (psychogenic) tics.

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    Demartini, B; Ricciardi, L; Parees, I; Ganos, C; Bhatia, K P; Edwards, M J

    2015-03-01

    Functional tics, also called psychogenic tics or pseudo-tics, are difficult to diagnose because of the lack of diagnostic criteria and their clinical similarities to organic tics. The aim of the present study was to report a case series of patients with documented functional tics and to describe their clinical characteristics, risk factors and psychiatric comorbidity. Also clinical tips are suggested which might help the differential diagnosis in clinical practice. Eleven patients (mean age at onset 37.2, SD 13.5; three females) were included with a documented or clinically established diagnosis of functional tics, according to consultant neurologists who have specific expertise in functional movement disorders or in tic disorders. Adult onset, absent family history of tics, inability to suppress the movements, lack of premonitory sensations, absence of pali-, echo- and copro-phenomena, presence of blocking tics, the lack of the typical rostrocaudal tic distribution and the coexistence of other functional movement disorders were common in our patients. Our data suggest that functional tics can be differentiated from organic tics on clinical grounds, although it is also accepted that this distinction can be difficult in certain cases. Clinical clues from history and examination described here might help to identify patients with functional tics. © 2014 EAN.

  13. Detection of EpCAM-positive microparticles in pleural fluid: A new approach to mini-invasively identify patients with malignant pleural effusions.

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    Roca, Elisa; Lacroix, Romaric; Judicone, Coralie; Laroumagne, Sophie; Robert, Stéphane; Cointe, Sylvie; Muller, Alexandre; Kaspi, Elise; Roll, Patrice; Brisson, Alain R; Tantucci, Claudio; Astoul, Philippe; Dignat-George, Françoise

    2016-01-19

    Pleural biomarkers allowing to mini-invasively discriminate benign from malignant pleural effusions are needed. Among potential candidates, microparticles (MPs) are extracellular vesicles that vectorize antigen derived from the parent cell. We hypothesized that tumor-derived MPs could be present in the pleural liquid and help to identify patients with malignant pleural effusions. Using highly sensitive flow cytometry and cryo-electron microscopy, we showed that large amounts of MPs from hematopoïetic and vascular origin could be detectable in pleural fluids. Their level did not differ between benign (n = 14) and malignant (n = 71) pleural effusions. Analysis of selected tumoral associated antigens (podoplanin, mucin 1 and EpCAM, epithelial-cell-adhesion-molecule) evidenced for the first time the presence of tumor-derived MPs expressing EpCAM in malignant pleural fluids only (Specificity = 93%, Sensitivity = 49% and 45% for flow cytometry and ELISA, respectively). The detection of EpCAM-positive-MPs (EpCAM + MPs) by flow cytometry showed a better specificity and sensitivity than ELISA to distinguish between pleural carcinoma and the others malignant pleural effusions (MPE; Sp: 96% vs 89%; Se: 79% vs 66%). Combining EpCAM+ MPs and cytology improved the diagnosis of MPE compared to cytology alone. This study establishes the basis for using EpCAM+ MPs as a promising new biomarker that could be added to the armamentarium to mini-invasively identify patients with malignant pleural effusions.

  14. Diagnosis and Treatment of Benign Paroxysmal Positional Vertigo

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    Muhammed Dagkiran

    2015-12-01

    Full Text Available Benign paroxysmal positional vertigo is the cause of peripheral vertigo, which only takes seconds posed by certain head and body position and led to severe attacks of vertigo. Therefore, it is a disturbance that causes a continuous fear of fall and anxiety in some patients. Although benign paroxysmal positional vertigo is the most common cause of peripheral vertigo, it may cause unnecessary tests, treatment costs and the loss of labor due to the result of the delay in the diagnosis and treatment stages. Diagnosis and treatment of this disease is easy. High success rates can be achieved with appropriate repositioning maneuvers after taking a detailed medical history and accurate assessment of accompanying nystagmus. The aim of this paper was to review the updated information about benign paroxysmal positional vertigo. [Archives Medical Review Journal 2015; 24(4.000: 555-564

  15. DIAGNOSIS OF FINANCIAL POSITION BY BALANCE SHEET ANALYSIS - CASE STUDY

    OpenAIRE

    Hada Teodor; Marginean Radu

    2013-01-01

    This study aims to elucidate and to exemplify an important technique for assessing the economic entities, namely the fundamental analysis of the balance sheet, in several significant aspects. The analysis of financial data reported in the balance sheet are, for an economic entity, the basis of a principle diagnosis by determining specific indicators of economic and financial analysis. This analysis aims to provide an insight into the companyâ€(tm)s financial position. The stated aim of this s...

  16. Reliability of an anamnestic questionnaire for the diagnosis of benign paroxysmal positional vertigo in the elderly.

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    Lapenna, Ruggero; Faralli, Mario; Del Zompo, Maria Rita; Cipriani, Laura; Mobaraki, Puya Dehgani; Ricci, Giampietro

    2016-10-01

    There is common agreement in the literature that it can result in an underestimation of benign paroxysmal positional vertigo (BPPV) in the elderly. The aim of this work was to analyze the role of anamnesis in the diagnosis of BPPV in patients of different ages through the development and validation of a scored questionnaire. The questionnaire is based on the presence/absence of six typical anamnestic features of BPPV. The Mini-Mental State Exam (MMS) was also administered to patients over 65 years of age. Bedsides, examination for BPPV was then carried out, assigning the outcome of the questionnaire and eventual MMS to the final diagnosis for each patient. The sensitivity and specificity of the questionnaire for high scores (>8) were found to be, respectively, 86 % and 80 % in all patients, 94 and 71 % in those under 65 years of age, 78 and 90 % in patients over 65, and, in particular, 63 and 83 % in those with MMS >24 and 100 and 100 % in those with MMS ≤24. The reliability and average score of the questionnaire were statistically significantly lower in the group of elderly patients without cognitive deficits. The lower reliability of the questionnaire in the geriatric population, rather than the presence of cognitive deterioration, seems to correlate with other comorbidities or simply to a lower mobility of the head triggering positional symptoms. The use of the questionnaire could however reduce the risk of a missed diagnosis of BPPV given its good reliability across all ages.

  17. High-resolution mini gamma camera for diagnosis and radio-guided surgery in diabetic foot infection

    International Nuclear Information System (INIS)

    Scopinaro, F.; Capriotti, G.; Di Santo, G.; Capotondi, C.; Micarelli, A.; Massari, R.; Trotta, C.; Soluri, A.

    2006-01-01

    The diagnosis of diabetic foot osteomyelitis is often difficult. 99m Tc-WBC (White Blood Cell) scintigraphy plays a key role in the diagnosis of bone infections. Spatial resolution of Anger camera is not always able to differentiate soft tissue from bone infection. Aim of present study is to verify if HRD (High-Resolution Detector) is able to improve diagnosis and to help surgery. Patients were studied by HRD showing 25.7x25.7 mm 2 FOV, 2 mm spatial resolution and 18% energy resolution. The patients were underwent to surgery and, when necessary, bone biopsy, both guided by HRD. Four patients were positive at Anger camera without specific signs of osteomyelitis. HRS (High-Resolution Scintigraphy) showed hot spots in the same patients. In two of them the hot spot was bar-shaped and it was localized in correspondence of the small phalanx. The presence of bone infection was confirmed at surgery, which was successfully guided by HRS. 99m Tc-WBC HRS was able to diagnose pedal infection and to guide the surgery of diabetic foot, opening a new way in the treatment of infected diabetic foot

  18. High-resolution mini gamma camera for diagnosis and radio-guided surgery in diabetic foot infection

    Energy Technology Data Exchange (ETDEWEB)

    Scopinaro, F. [Department of Radiological Sciences, University ' La Sapienza' Rome (Italy); Capriotti, G. [Department of Radiological Sciences, University ' La Sapienza' Rome (Italy); Di Santo, G. [Department of Radiological Sciences, University ' La Sapienza' Rome (Italy); Capotondi, C. [Unit of Radiology, S. Andrea Hospital, Rome (Italy); Micarelli, A. [Nuclear Medicine, Sulmona Hospital, Sulmona (AQ) (Italy); Massari, R. [Institute of Biomedical Engineering, ISIB-CNR, Rome-Li-tech srl, Lauzacco Pavia di Udine (UD) (Italy); Trotta, C. [Institute of Biomedical Engineering, ISIB-CNR, Rome-Li-tech srl, Lauzacco Pavia di Udine (UD) (Italy); Soluri, A. [Institute of Biomedical Engineering, ISIB-CNR, Rome-Li-tech srl, Lauzacco Pavia di Udine (UD) (Italy)]. E-mail: soluri@isib.cnr.it

    2006-12-20

    The diagnosis of diabetic foot osteomyelitis is often difficult. {sup 99m}Tc-WBC (White Blood Cell) scintigraphy plays a key role in the diagnosis of bone infections. Spatial resolution of Anger camera is not always able to differentiate soft tissue from bone infection. Aim of present study is to verify if HRD (High-Resolution Detector) is able to improve diagnosis and to help surgery. Patients were studied by HRD showing 25.7x25.7 mm{sup 2} FOV, 2 mm spatial resolution and 18% energy resolution. The patients were underwent to surgery and, when necessary, bone biopsy, both guided by HRD. Four patients were positive at Anger camera without specific signs of osteomyelitis. HRS (High-Resolution Scintigraphy) showed hot spots in the same patients. In two of them the hot spot was bar-shaped and it was localized in correspondence of the small phalanx. The presence of bone infection was confirmed at surgery, which was successfully guided by HRS. {sup 99m}Tc-WBC HRS was able to diagnose pedal infection and to guide the surgery of diabetic foot, opening a new way in the treatment of infected diabetic foot.

  19. Benign paroxysmal positional vertigo in outpatient practice: Diagnosis and treatment

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    N. V. Bestuzheva

    2014-01-01

    Full Text Available Dizziness is one of the common reasons for visits to physicians of various specialties; the data of foreign investigations show that benign paroxysmal positional vertigo (BPPV is most frequently encountered.Objective: to study the causes of dizziness, to analyze the frequency of BPPV and the efficiency of its treatment in outpatient practice.Patients and methods. The investigation enrolled 80 patients, including 55 (68.7% women and 25 (31.3% men, aged 18 to 75 years (mean age 53.8±12.8 years, who complained of dizziness and sought for medical advice in the Therapeutic-and-Diagnostic Unit, A.Ya. Kozhevnikov Clinic of Nervous System Diseases, I.M. Sechenov First Moscow State Medical University.Results. The most common causes of dizziness in outpatient practice were BPPV (46.2% and postural phobic vertigo (35%. The diagnosis of VPPV, if special positional testing (Dix-Hallpike and McClure-Pagnini tests was carried out, was shown to create no significant difficulties. The diagnosis was not established in the majority (97.5% of the patients; effective treatment was performed in one of the patients. Combined treatment, by performing the positional tests and using betaserc for 2 months, led to complete resolution of positional vertigo in most (97.3% patients.Discussion. The findings indicate the efficiency of examining patients with complaints of dizziness, by using the special otoneurological tests to detect BPPV. The purposeful questioning of patients with BPPV can suspect this disease in the majority of cases. Our investigation shows the high efficiency of rehabilitation maneuvers for BPPV, which agrees well with the data of other authors. Physicians’ poor awareness of BPPV among physicians and the high efficiency of its treatment in outpatient practice are noted.

  20. Insertion torque recordings for the diagnosis of contact between orthodontic mini implants and dental roots: protocol for a systematic review

    NARCIS (Netherlands)

    Meursinge Reynders, R.; Ladu, L.; Ronchi, L.; Di Girolama, N.; de Lange, J.; Roberts, N.; Plüddemann, A.

    2015-01-01

    Background Hitting a dental root during the insertion of orthodontic mini-implants (OMIs) is a common adverse effect of this intervention. This condition can permanently damage these structures and can cause implant instability. Increased torque levels (index test) recorded during the insertion of

  1. Insertion torque recordings for the diagnosis of contact between orthodontic mini-implants and dental roots: a systematic review

    NARCIS (Netherlands)

    Meursinge Reynders, Reint; Ladu, Luisa; Ronchi, Laura; Di Girolamo, Nicola; de Lange, Jan; Roberts, Nia; Plüddemann, Annette

    2016-01-01

    Most orthodontic mini-implants (OMIs) are inserted between dental roots. The prevalence of contacting these structures is high. Such contacts can cause permanent root damage and implant instability. Increased torque levels during implant insertion (the index test) could be a more accurate and

  2. DIAGNOSIS AND MANAGEMENT BENIGN PAROXYSMAL POSITIONAL VERTIGO (BPPV

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    Putu Prida Purnamasari

    2013-05-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 Benign Paroxysmal Positional Vertigo (BPPV is one of the most frequent Neurotology disorders. Benign Paroxysmal Positional Vertigo is a vestibular disorder in which 17% -20% of patients complained of vertigo. In the general population the prevalence of BPPV is between 11 to 64 per 100,000 (prevalence 2.4%. Benign Paroxysmal Positional Vertigo is a disturbance in the inner ear with positional vertigo symptoms that occur repeatedly with the typical nystagmus paroxysmal. The disorders can be caused either by canalithiasis or cupulolithiasis and could in theory be about three semicircular canals, although superior canal (anterior is very rare. The most common is the form of the posterior canal, followed by a lateral. The diagnosis of BPPV can be enforced based on history and physical examination, including some tests such as Dix-Hallpike test, caloric test, and Supine Roll test. The diagnosis of BPPV is also classified according to the types of channels. Management of BPPV include non-pharmacological, pharmacological and operations. Treatment is often used non-pharmacological includes several maneuvers such as Epley maneuver, Semount maneuver, Lempert maneuver, forced prolonged position and Brandt-Daroff exercises. /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}

  3. Non-invasive prenatal diagnosis of monogenic disorders: an optimized protocol using MEMO qPCR with miniSTR as internal control.

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    Guissart, Claire; Debant, Vanessa; Desgeorges, Marie; Bareil, Corinne; Raynal, Caroline; Toga, Caroline; Pritchard, Victoria; Koenig, Michel; Claustres, Mireille; Vincent, Marie-Claire

    2015-02-01

    Analysis of circulating cell-free fetal DNA (cffDNA) in maternal plasma is very promising for early diagnosis of monogenic diseases. However, this approach is not yet available for routine use and remains technically challenging because of the low concentration of cffDNA, which is swamped by the overwhelming maternal DNA. To make clinical applications more readily accessible, we propose a new approach based on mutant enrichment with 3'-modified oligonucleotides (MEMO) PCR along with real-time PCR to selectively amplify from the maternal blood the paternally inherited fetal allele that is not present in the maternal genome. The first proof of concept of this strategy was displayed for cystic fibrosis by the accuracy of our detection of the p.Gly542* mutation used as the initial developmental model. Subsequently, a retrospective study of plasmas originating from two pregnant women carrying a fetus with private mutation confirmed the effectiveness of our method. We confirmed the presence of cffDNA in the studied samples by the identification of a tri-allelic DNA profile using a miniSTR kit. This new non-invasive prenatal diagnosis test offers numerous advantages over current methods: it is simple, cost effective, time efficient and does not require complex equipment or bioinformatics settings. Moreover, our assays for different private mutations demonstrate the viability of this approach in clinical settings for monogenic disorders.

  4. Evaluation of the implantation position of mini-screws for orthodontic treatment in the maxillary molar area by a micro CT

    International Nuclear Information System (INIS)

    Ishii, Takenobu; Nojima, Kunihiko; Nishii, Yasushi; Takaki, Takashi; Yamaguchi, Hideharu

    2004-01-01

    The interalveolar septum between the upper first molar and the second premolar of the separated human maxillary bone was three-dimensionally observed by micro CT to evaluate the appropriate mini-screw type implant placement position by considering the relationship between the tooth roots and the maxillary sinus. After taking micro CTs of 5 human maxillary bones, horizontally sectioned images of the interalveolar septum area 2, 4, 6, 8, 10, and 12 mm deep from the crest of the alveolar ridge were reconstructed by three-dimensional reconstruction software. The bucco-lingual and mesio-distal lengths and area in each sectioned interalveolar septum were measured using digital image measurement software. Using the results, the interalveolar septum area between the upper first molar and the second premolar approximately 6-8 mm deep from the alveolar crest in the tooth root apical direction was determined to be the safest position for mini-screw implantation. Furthermore, lateral implantation from the palatal side was deduced to be the safest approach. (author)

  5. Insertion torque recordings for the diagnosis of contact between orthodontic mini-implants and dental roots: a systematic review.

    Science.gov (United States)

    Meursinge Reynders, Reint; Ladu, Luisa; Ronchi, Laura; Di Girolamo, Nicola; de Lange, Jan; Roberts, Nia; Plüddemann, Annette

    2016-03-31

    Most orthodontic mini-implants (OMIs) are inserted between dental roots. The prevalence of contacting these structures is high. Such contacts can cause permanent root damage and implant instability. Increased torque levels during implant insertion (the index test) could be a more accurate and immediate measure for diagnosing implant-root contact (the target condition) than radiographs (the reference standard) and could ultimately lead to a reduction or elimination of X-ray exposure. To address this issue, we asked three questions: (1) whether OMIs with root contact had higher insertion torque values than those without, (2) what is the accuracy of the index test compared with the reference standard to diagnose the target condition and what are the adverse effects of the index test, and (3) whether intermediate torque values have clinical diagnostic utility. Methods were conducted according to our published protocol, which was based on the PRISMA-P 2015 statement. We applied broad spectrum eligibility criteria that included randomized and non-randomized studies on clinical, animal, and cadaver models. Not including such models would be unethical because it could slow down knowledge creation on the adverse effects of implant insertion. We conducted searches in more than 40 electronic databases including MEDLINE and 10 journals were hand-searched. Grey literature and reference lists were also searched. All research procedures were conducted independently by three reviewers. Authors of selected studies were contacted to obtain additional information. Outcomes on the three different research models were analysed separately. Systematic error was assessed with the Cochrane 'Risk of bias tool' for non-randomized studies. One clinical, two animal, and two cadaver studies fulfilled the eligibility criteria of the first research question. All studies and subgroups demonstrated higher insertion torque values for OMIs with the target condition than those without. Mean

  6. Positive muscle phenomena-diagnosis, pathogenesis and associated disorders

    NARCIS (Netherlands)

    Kortman, Hans G.; Veldink, Jan H.; Drost, Gea

    Positive muscle phenomena arise owing to various forms of spontaneous muscle hyperactivity originating in motor neurons or in the muscle itself. Although they are common in a wide range of neurological and non-neurological diseases, clinical and scientific data on these phenomena are limited, and

  7. Investigating Initial Disclosures and Reactions to Unexpected, Positive HPV Diagnosis.

    Science.gov (United States)

    Smith, Rachel A; Hernandez, Rachael; Catona, Danielle

    2014-07-01

    Initial disclosures of health conditions are critical communication moments. Existing research focuses on disclosers; integrating confidants into studies of initial disclosures is needed. Guided by the disclosure decision-making model (DD-MM; Greene, 2009), this study examined what diagnosed persons and confidants may say when faced with unexpected test results and unexpected disclosures, respectively. Participants ( N = 151) recorded an audio-visual message for another person, after imagining that they or the other person had just received unexpected, positive HPV test results. The qualitative analysis revealed four themes: (1) impression management and social distance, (2) invisible symptoms and advice regarding future disclosures, (3) expressing and acknowledging emotional reactions, and (4) misunderstandings and lacking knowledge about HPV. These findings suggested that DD-MM may be a relevant framework for understanding not only when disclosers share, but what disclosers and confidants say in early conversations about new diagnoses. While disclosers' and confidants' messages showed marked similarities, important differences appeared. For example, confidants focused on assuaging disclosers' fear about the consequences, whereas disclosers expressed distress related to their uncertainty about the prognosis of an HPV infection and how to prepare for next steps. The discussion highlighted implications for the DD-MM, HPV disclosures, and future interventions.

  8. Prenatal radiographic diagnosis of alpha-fetoprotein positive malformations in early pregnancy

    International Nuclear Information System (INIS)

    Probst, F.P.; Sigurd, J.

    1980-01-01

    Early diagnosis of two malformed fetuses with positive alpha-fetoprotein test of the amniotic fluid with the aid of amniography is reported. Radiographic, diagnostic and prognostic aspects are discussed. (Auth.)

  9. Development of mini linac-based positron source and an efficient positronium convertor for positively charged antihydrogen production

    Science.gov (United States)

    Muranaka, T.; Debu, P.; Dupré, P.; Liszkay, L.; Mansoulie, B.; Pérez, P.; Rey, J. M.; Ruiz, N.; Sacquin, Y.; Crivelli, P.; Gendotti, U.; Rubbia, A.

    2010-04-01

    We have installed in Saclay a facility for an intense positron source in November 2008. It is based on a compact 5.5 MeV electron linac connected to a reaction chamber with a tungsten target inside to produce positrons via pair production. The expected production rate for fast positrons is 5·1011 per second. The study of moderation of fast positrons and the construction of a slow positron trap are underway. In parallel, we have investigated an efficient positron-positronium convertor using porous silica materials. These studies are parts of a project to produce positively charged antihydrogen ions aiming to demonstrate the feasibility of a free fall antigravity measurement of neutral antihydrogen.

  10. Development of mini linac-based positron source and an efficient positronium convertor for positively charged antihydrogen production

    International Nuclear Information System (INIS)

    Muranaka, T; Debu, P; Dupre, P; Liszkay, L; Mansoulie, B; Perez, P; Rey, J M; Ruiz, N; Sacquin, Y; Crivelli, P; Gendotti, U; Rubbia, A

    2010-01-01

    We have installed in Saclay a facility for an intense positron source in November 2008. It is based on a compact 5.5 MeV electron linac connected to a reaction chamber with a tungsten target inside to produce positrons via pair production. The expected production rate for fast positrons is 5·10 11 per second. The study of moderation of fast positrons and the construction of a slow positron trap are underway. In parallel, we have investigated an efficient positron-positronium convertor using porous silica materials. These studies are parts of a project to produce positively charged antihydrogen ions aiming to demonstrate the feasibility of a free fall antigravity measurement of neutral antihydrogen.

  11. Development of mini linac-based positron source and an efficient positronium convertor for positively charged antihydrogen production

    Energy Technology Data Exchange (ETDEWEB)

    Muranaka, T; Debu, P; Dupre, P; Liszkay, L; Mansoulie, B; Perez, P; Rey, J M; Ruiz, N; Sacquin, Y [Irfu, CEA-Saclay, F-91191 Gif-sur-Yvette Cedex (France); Crivelli, P; Gendotti, U; Rubbia, A, E-mail: tomoko.muranaka@cea.f [Institut fuer TelichenPhysik, ETHZ, CH-8093 Zuerich (Switzerland)

    2010-04-01

    We have installed in Saclay a facility for an intense positron source in November 2008. It is based on a compact 5.5 MeV electron linac connected to a reaction chamber with a tungsten target inside to produce positrons via pair production. The expected production rate for fast positrons is 5{center_dot}10{sup 11} per second. The study of moderation of fast positrons and the construction of a slow positron trap are underway. In parallel, we have investigated an efficient positron-positronium convertor using porous silica materials. These studies are parts of a project to produce positively charged antihydrogen ions aiming to demonstrate the feasibility of a free fall antigravity measurement of neutral antihydrogen.

  12. [Validity and Reliability Studies of Modified Mini Mental State Examination (MMSE-E) For Turkish Illiterate Patients With Diagnosis of Alzheimer Disease].

    Science.gov (United States)

    Babacan-Yıldız, Gülsen; Ur-Özçelik, Emel; Kolukısa, Mehmet; Işık, Ahmet Turan; Gürsoy, Esra; Kocaman, Gülşen; Çelebi, Arif

    2016-01-01

    To investigate the validity and reliability of modified Mini Mental State Examination (MMSE-E) for illiterate patients in a Turkish population with Alzheimer's disease (AD). A total of 107 illiterate patients with Alzheimer's Disease (women: 65, men: 42) and 68 illiterate healthy volunteer subjects (women: 36, men: 32) were included in the study. MMSE-I and Geriatrics Depression Scale were performed on all subjects, Alzheimer patients were also administered Basic Activities of Daily Living (B- ADL). Clinical Dementia Rating (CDR) was used to determine the severity of disease, while a receiver operating characteristic (ROC) analysis was performed to analyze the cut-off scores of MMSE-I, and the positive/negative predictive values that were calculated for the optimal cut-off scores. Internal consistency was measured using Cronbach's coefficient . Additionally, correlations between total MMSE-I score and the CDR, B-ADL, and GDS scores were examined. The MMSE-I scores significantly and inversely correlated with CDR (-0.82, p=0.000) and B-ADL scores (-0.051, p=0.000). The optimal cut-off points of MMSE-I were 23/24, which yielded a sensitivity of 99.0% - %100.0, a specificity of 98.5% - 97.0%, and an AUC of 1.0/1.0, respectively. Reliability of the MMSE-I was high α = 0.70). The total MMSE-I score was able to differentiate the AD group from the control group.

  13. Control rod position fault diagnosis and its software realization of pressurized water reactor

    International Nuclear Information System (INIS)

    Chang Zhengke; Shao Dinghong

    2004-11-01

    PLC software is adopted in the Rod Position Monitoring System of QS2NPS. By this software, the position of control rods can be monitored in real time, the abnormal phenomena can be identified immediately, the correctness and timeliness of fault diagnosis are improved remarkably. the identification and recordance of rod position fault, the performance validation of measure channel are realized also. The function and effect of this software are introduced. (authors)

  14. Insertion torque recordings for the diagnosis of contact between orthodontic mini-implants and dental roots: protocol for a systematic review.

    Science.gov (United States)

    Meursinge Reynders, Reint; Ladu, Luisa; Ronchi, Laura; Di Girolamo, Nicola; de Lange, Jan; Roberts, Nia; Plüddemann, Annette

    2015-04-02

    Hitting a dental root during the insertion of orthodontic mini-implants (OMIs) is a common adverse effect of this intervention. This condition can permanently damage these structures and can cause implant instability. Increased torque levels (index test) recorded during the insertion of OMIs may provide a more accurate and immediate diagnosis of implant-root contact (target condition) than radiographic imaging (reference standard). An accurate index test could reduce or eliminate X-ray exposure. These issues, the common use of OMIs, the high prevalence of the target condition, and because most OMIs are placed between roots warrant a systematic review. We will assess 1) the diagnostic accuracy and the adverse effects of the index test, 2) whether OMIs with root contact have higher insertion torque values than those without, and 3) whether intermediate torque values have clinical diagnostic utility. The Preferred Reporting Items for Systematic review and Meta-Analysis Protocols (PRISMA-P) 2015 statement was used as a the guideline for reporting this protocol. Inserting implants deliberately into dental roots of human participants would not be approved by ethical review boards and adverse effects of interventions are generally underreported. We will therefore apply broad spectrum eligibility criteria, which will include clinical, animal and cadaver models. Not including these models could slow down knowledge translation. Both randomized and non-randomized research studies will be included. Comparisons of interest and subgroups are pre-specified. We will conduct searches in MEDLINE and more than 40 other electronic databases. We will search the grey literature and reference lists and hand-search ten journals. All methodological procedures will be conducted by three reviewers. Study selection, data extraction and analyses, and protocols for contacting authors and resolving conflicts between reviewers are described. Designed specific risk of bias tools will be tailored

  15. The diagnosis of a fully flexed neck position MRI diagnosis in juvenile muscular atrophy of the distal upper extremity

    International Nuclear Information System (INIS)

    Liu Huaijun; Li Caiying; He Dan; Chi Chen; Cui Caixia; Huang Boyuan; Wang Guoshi; Zhu Qingfeng

    2006-01-01

    Objective: To investigate the value of the diagnosis of MRI during neck flexion in juvenile muscular atrophy of the distal upper extremity. Methods: Five young male patients (mean age 21 years old) with clinical and electrophysiological alterations were performed MR examination with routine neck position and a fully flexed neck position. Eight age-match young men were examined as control subjects. SE T 1 WI, T 2 WI, Fluid-attenuated inversion recovery (FLAIR) sequences were scanned. Results: A distinctive finding in the disorder was forward displacement of the cervical dural sac, compressive flattening of the lower cervical cord during neck flexion and flow void in the posterior epidural space. The forward displacement was significantly greater in patients than in age-matched control subjects. Conclusion: Flexed neck position MRI is helpful to find radiological abnormalities of the lower cervical dural sac and spinal cord, which were combined with clinical disorder to diagnose juvenile muscular atrophy of the distal upper extremity. (authors)

  16. Detection of dementia in primary care: comparison of the original and a modified Mini-Cog Assessment with the Mini-Mental State Examination.

    Science.gov (United States)

    Kamenski, Gustav; Dorner, Thomas; Lawrence, Kitty; Psota, Georg; Rieder, Anita; Schwarz, Franz; Sepandj, Asita; Spiegel, Wolfgang; Strotzka, Stefan

    2009-12-01

    Background Dementia is considered widely under-detected in primary care, and general practitioners (GPs) frequently ask for easy to use tools to assist in its early detection.Aim To determine the degree of correlation between the Mini-Cog Assessment (Mini-Cog) as performed by GPs and the Mini-Mental State Examination (MMSE).Design of study This was a prospective study (2005, 2006) comparing two cognitive screening instruments.Setting Ten general practices in Austria, with patients with a hitherto undiagnosed suspicion of dementia seen consecutively.Method Sensitivity, specificity and positive and negative predictive values (PPVs and NPVs) of the Mini-Cog (applying both a colour-coded and the original rating method) were assessed for degree of correlation with the MMSE. In phase one GPs examined patients suspected of having dementia using the Mini-Cog; in phase two a neurologist retested them applying the MMSE, a clock-drawing test (CDT) and a routine clinical examination. A questionnaire on the practicability of the Mini-Cog was answered by GPs.Results Of the 107 patients who participated 86 completed the whole study protocol. The Mini-Cog, as performed by the ten GPs, displayed a sensitivity of 0.85 (95% CI: 0.71, 0.98), a specificity of 0.58 (95% CI: 0.46, 0.71), a PPV of 0.47 (95% CI: 0.33, 0.61) and an NPV of 0.90 (95% CI: 0.80, 0.99) as against the MMSE carried out by neurologists. The GPs judged the Mini-Cog useful and time saving.Conclusion The Mini-Cog has a high sensitivity and acceptable specificity in the general practice setting and has proved to be a practicable tool for the diagnosis of dementia in primary care.

  17. Insertion torque recordings for the diagnosis of contact between orthodontic mini-implants and dental roots: protocol for a systematic review

    NARCIS (Netherlands)

    Meursinge Reynders, Reint; Ladu, Luisa; Ronchi, Laura; Di Girolamo, Nicola; de Lange, Jan; Roberts, Nia; Plüddemann, Annette

    2015-01-01

    Hitting a dental root during the insertion of orthodontic mini-implants (OMIs) is a common adverse effect of this intervention. This condition can permanently damage these structures and can cause implant instability. Increased torque levels (index test) recorded during the insertion of OMIs may

  18. Analysis of false positive and false negative cytological diagnosis of breast lesions

    International Nuclear Information System (INIS)

    Jamal, Awtif A.; Mansoor, I.

    2001-01-01

    To study the reasons for interpretive errors in false negative and false positive diagnosis of breast carcinoma on fine needle aspiration cytology material. We reviewed only those cases in which cytohistological discrepancies were found, where the cytologic material was abnormal and to some extent misinterpreted or both. There was only one false negative case (false negative fraction 0.32%) proved histologically as ductal carcinoma and four false positive cases (false positive fraction 1.2%); 2 fibroadenoma; 1 fibrocystic disease; and 1 stromal fibrosis. Smears of the two false positive fibroadenoma cases showed very high cellularity, overcrowded clusters and frequent stripped nuclei. The fibrocystic case showed tight clusters of apocrine cells and sheets of loosely aggregated macrophages that were over interpreted. Smears of the false negative ductal carcinoma was hypocellular overall, and the cells showed minimal nuclear pleomorphism. Overcrowded clusters and hypercellular smears should be carefully assessed for uniformity of cells and detailed nuclear and cytomorphological features. If the full-blown malignant cytomorphological changes are not visible, a diagnosis of suspicious or inconclusive should be made and frozen section recommended before surgery. Hypocellularity and relatively nuclear monomorphism are the reasons for failure to diagnose malignant breast lesions. Careful attention should be paid to extreme nuclear monomorphism and absence of naked bipolar cells. A cytologically atypical or suspicious diagnosis together with positive radiological and clinical findings should suggest a diagnosis of malignancy. (author)

  19. Imaging diagnosis--positive contrast peritoneographic features of true diaphragmatic hernia.

    Science.gov (United States)

    Choi, Jihye; Kim, Hyunwook; Kim, Mieun; Yoon, Junghee

    2009-01-01

    A true diaphragmatic hernia is a congenital diaphragmatic malformation that can appear identical to a peritoneopericardial diaphragmatic hernia (PPDH). True diaphragmatic hernias are rare in dogs. Herein we describe the use of positive contrast peritoneography for diagnosis of a true diaphragmatic hernia in two dogs.

  20. Validity and applicability of the Mini International Neuropsychiatric Interview administered by family medicine residents in primary health care in Brazil.

    Science.gov (United States)

    de Azevedo Marques, João Mazzoncini; Zuardi, Antonio W

    2008-01-01

    To evaluate the validity and applicability of the Mini International Neuropsychiatric Interview (MINI) used by family medicine residents in primary health care (PHC) in Brazil. Training for administrating the MINI was given as part of a broad psychiatry education program. Interviews were held with 120 PHC patients who were at least 15 years old. MINI was administered by 25 resident physicians, while the Structured Clinical Interview for Diagnosis (SCID) was administered by a psychiatrist blind to patients' results on the MINI, and the diagnoses on both interviews were compared. The resident physicians answered questions on the applicability of the MINI. Concordance levels for any mental disorder, the broader current diagnostic categories and the most common specific diagnoses were analyzed. Kappa coefficients ranged between 0.65 and 0.85; sensitivity, between 0.75 and 0.92; specificity, between 0.90 and 0.99; positive predictive values (PPV), between 0.60 and 0.86; negative predictive values (NPV), between 0.92 and 0.99; and accuracy, between 0.88 and 0.98. The resident physicians considered MINI comprehensibility and clinical relevance satisfactory. These good psychometric results in a real-world setting may be related to a special training program, which is more frequent, intensive and diversified. In these conditions, the MINI is a useful tool for general practitioners.

  1. Pre-Hospital Fast Positive Cases Identified by DFB Ambulance Paramedics – Final Clinical Diagnosis

    LENUS (Irish Health Repository)

    Feeney, A

    2016-04-01

    Ischaemic stroke clinical outcomes are improved by earlier treatment with intravenous thrombolysis. An existing pathway at the Mater University Hospital for assessment of suspected acute stroke in the Emergency Department was updated, aiming to shorten ‘door to needle time’. This study examines the final clinical diagnosis of Dublin Fire Brigade Ambulance Paramedic identified Face Arm Speech Test (FAST) positive patients presenting to the Emergency Department over a 7 month period. A retrospective analysis was carried out of 177 consecutive FAST positive patients presenting between March and November 2014. The final clinical diagnosis was acute stroke in 57.1% (n=101) of patients. Of these, 76 were ischaemic strokes of whom 56.5% (n=43) were thrombolysed. In the pre-hospital setting Ambulance Paramedics can identify, with reasonable accuracy, acute stroke using the FAST test. Over half of the ischaemic stroke patients presenting via this pathway can be treated with intravenous thrombolysis

  2. Positive predictive value of the infant respiratory distress syndrome diagnosis in the Danish National Patient Registry

    Directory of Open Access Journals (Sweden)

    Thygesen SK

    2013-08-01

    Full Text Available Sandra Kruchov Thygesen, Morten Olsen, Christian Fynbo ChristiansenDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, DenmarkBackground: Infant respiratory distress syndrome (IRDS is the most common respiratory disease in preterm infants, and is associated with considerable morbidity and mortality. Valid data on IRDS are important in clinical epidemiological research.Objectives: The objective of this study was to estimate the positive predictive value (PPV of the IRDS diagnosis registered in the population-based Danish National Patient Registry according to the International Classification of Diseases, 8th and 10th revisions.Methods: Between January 1, 1977 and December 31, 2008, we randomly selected three patients per year, 96 in total, who were registered with an IRDS diagnosis in the Danish National Patient Registry and living in the northern part of Denmark. Data on the infants included information on the presence of predefined clinical symptoms. We defined IRDS as the presence of at least two of four clinical symptoms (tachypnea, retractions or nasal flaring, grunting, and central cyanosis, which had to be present for more than 30 minutes. Using medical record review as the reference standard, we computed the positive predictive value of the registered IRDS diagnosis including 95% confidence intervals (CIs.Results: We located the medical record for 90 of the 96 patients (94%, and found an overall PPV of the IRDS diagnosis of 81% (95% CI 72%–88%. This did not vary substantially between primary and secondary diagnoses. The PPV was higher, at 89% (95% CI 80%–95%, for preterm infants born before 37 weeks of gestation.Conclusion: The PPV of the IRDS diagnosis in the Danish National Patient Registry is reasonable when compared with symptoms described in the corresponding medical records. The Danish National Patient Registry is a useful data source for studies of IRDS, particularly if restricted to preterm infants

  3. Detection of EpCAM-positive microparticles in pleural fluid: A new approach to mini-invasively identify patients with malignant pleural effusions

    OpenAIRE

    Roca, Elisa; Lacroix, Romaric; Judicone, Coralie; Laroumagne, Sophie; Robert, St?phane; Cointe, Sylvie; Muller, Alexandre; Kaspi, Elise; Roll, Patrice; Brisson, Alain R.; Tantucci, Claudio; Astoul, Philippe; Dignat-George, Fran?oise

    2015-01-01

    Pleural biomarkers allowing to mini-invasively discriminate benign from malignant pleural effusions are needed. Among potential candidates, microparticles (MPs) are extracellular vesicles that vectorize antigen derived from the parent cell. We hypothesized that tumor-derived MPs could be present in the pleural liquid and help to identify patients with malignant pleural effusions. Using highly sensitive flow cytometry and cryo-electron microscopy, we showed that large amounts of MPs from hemat...

  4. The diagnosis and management of food allergies. Position paper of the Food Allergy Section the Polish Society of Allergology.

    Science.gov (United States)

    Bartuzi, Zbigniew; Kaczmarski, Maciej; Czerwionka-Szaflarska, Mieczysława; Małaczyńska, Teresa; Krogulska, Aneta

    2017-10-01

    The paper concerns the current position of the Polish Society of Allergology Food Allergy Section on the diagnosis and management of food allergies. The aim of this position is to provide evidence-based recommendations on the diagnosis and management of patients with allergic hypersensitivity to foods. This position statement includes a systematic review of studies in three areas, namely, the epidemiology, diagnosis and management of food allergies. While taking into account the specific Polish setting, in this publication we also used the current European Academy of Allergy and Clinical Immunology (EAACI) position paper and other current position statements, including those of the United States National Institute of Allergy and Infectious Diseases (NIAID).

  5. Mini-FLOTAC, an innovative direct diagnostic technique for intestinal parasitic infections: experience from the field.

    Science.gov (United States)

    Barda, Beatrice Divina; Rinaldi, Laura; Ianniello, Davide; Zepherine, Henry; Salvo, Fulvio; Sadutshang, Tsetan; Cringoli, Giuseppe; Clementi, Massimo; Albonico, Marco

    2013-01-01

    Soil-transmitted helminths and intestinal protozoa infection are widespread in developing countries, yet an accurate diagnosis is rarely performed. The aim of this study was to evaluate the recently developed mini-FLOTAC method and to compare with currently more widely used techniques for the diagnosis of intestinal parasitic infections in different settings. The study was carried out in Dharamsala, Himachal Pradesh, India, and in Bukumbi, Tanzania. A total of 180 pupils from two primary schools had their stool analyzed (n = 80 in Dharamsala and n = 100 in Bukumbi) for intestinal parasitic infections with three diagnostic methods: direct fecal smear, formol-ether concentration method (FECM) and mini-FLOTAC. Overall, 72% of the pupils were positive for any intestinal parasitic infection, 24% carried dual infections and 11% three infections or more. The most frequently encountered intestinal parasites were Entamoeba coli, Entamoeba histolytica/dispar, Giardia intestinalis, hookworm, (and Schistosoma mansoni, in Tanzania). Statistically significant differences were found in the detection of parasitic infections among the three methods: mini-FLOTAC was the most sensitive method for helminth infections (90% mini-FLOTAC, 60% FECM, and 30% direct fecal smear), whereas FECM was most sensitive for intestinal protozoa infections (88% FECM, 70% direct fecal smear, and 68% mini-FLOTAC). We present the first experiences with the mini-FLOTAC for the diagnosis of intestinal helminths and protozoa. Our results suggest that it is a valid, sensitive and potentially low-cost alternative technique that could be used in resource-limited settings--particularly for helminth diagnosis.

  6. Socioeconomic position and stage at diagnosis of head and neck cancer - a nationwide study from DAHANCA

    DEFF Research Database (Denmark)

    Olsen, Maja Halgren; Bøje, Charlotte Rotbøl; Kjær, Trille Kristina

    2015-01-01

    socioeconomic position and advanced stage HNSCC at diagnosis. MATERIAL AND METHODS: Men and women with HNSCC diagnosed between 1992 and 2008 were identified in the Danish Head and Neck Cancer Group (DAHANCA) database, which contains detailed information on all cases of HNSCC treated in Denmark. Individual...... information on the following four socioeconomic indicators: highest attained educational level, cohabitation status, disposable income and degree of urbanisation were obtained from Statistics Denmark. For the 9683 cases on which there was full information, we estimated odds ratios (ORs) for a diagnosis...... for hypopharynx cancer patients living in rural areas or provincial cities. Having one or more comorbid conditions was associated with an increased OR for advanced stage oral cancer but with a decreased OR for oropharynx cancer. CONCLUSION: In this nationwide population-based study, socioeconomic differences...

  7. Study of false positives in 5-ALA induced photodynamic diagnosis of bladder carcinoma

    Science.gov (United States)

    Draga, Ronald O. P.; Grimbergen, Matthijs C. M.; Kok, Esther T.; Jonges, Trudy G. N.; Bosch, J. L. H. R.

    2009-02-01

    Photodynamic diagnosis (PDD) is a technique that enhances the detection of tumors during cystoscopy using a photosensitizer which accumulates primarily in cancerous cells and will fluoresce when illuminated by violetblue light. A disadvantage of PDD is the relatively low specificity. In this retrospective study we aimed to identify predictors for false positive findings in PDD. Factors such as gender, age, recent transurethral resection of bladder tumors (TURBT), previous intravesical therapy (IVT) and urinary tract infections (UTIs) were examined for association with the false positive rates in a multivariate analysis. Data of 366 procedures and 200 patients were collected. Patients were instilled with 5-aminolevulinic acid (5-ALA) intravesically and 1253 biopsies were taken from tumors and suspicious lesions. Female gender and TURBT are independent predictors of false positives in PDD. However, previous intravesical therapy with Bacille Calmette-Guérin is also an important predictor of false positives. The false positive rate decreases during the first 9-12 weeks after the latest TURBT and the latest intravesical chemotherapy. Although shortly after IVT and TURBT false positives increase, PDD improves the diagnostic sensitivity and results in more adequate treatment strategies in a significant number of patients.

  8. Distinct trajectories of positive and negative affect after colorectal cancer diagnosis.

    Science.gov (United States)

    Ciere, Yvette; Janse, Moniek; Almansa, Josué; Visser, Annemieke; Sanderman, Robbert; Sprangers, Mirjam A G; Ranchor, Adelita V; Fleer, Joke

    2017-06-01

    Insight into trajectories of positive affect (PA) and negative affect (NA) across the cancer continuum may improve understanding of the nature of adjustment problems. The primary aim of this study was to identify subgroups of patients with distinct trajectories of PA and NA following diagnosis of colorectal cancer (CRC). Secondary to this aim, the co-occurrence between trajectories and their association with goal-related processes was explored. CRC patients (n = 186) completed questionnaires within 1 month, 7 months, and 18 months after diagnosis. Multilevel models were used to study the trajectory of PA and NA, as measured with the Positive and Negative Affect Schedule (PANAS). Four classes with distinct PA trajectories were identified: low (18.8%), increasing (6.7%), moderate (68.2%), and high (6.3%); 2 trajectories of NA emerged: low (36.3%) and moderate (63.7%). There was no significant association between PA and NA trajectory class probabilities. The average trajectory of PA covaried with levels of goal disturbance and goal reengagement over time, while the average NA trajectory covaried with goal disturbance and goal disengagement. Compared with the general population, our sample of cancer patients suffered from a lack of positive emotions, but not a high presence of negative emotions. About one fifth of patients reported low PA up to 18 months after diagnosis and may benefit from supportive care. Furthermore, the trajectory of PA was independent of that of NA and related with a distinct goal adjustment process (i.e., goal disengagement vs. goal reengagement). This finding indicates the need to tailor psychological care to the nature of the adjustment problem. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  9. Disclosure of diagnosis of multiple sclerosis in the workplace positively affects employment status and job tenure.

    Science.gov (United States)

    Kirk-Brown, A K; Van Dijk, P A; Simmons, R D; Bourne, M P; Cooper, B K

    2014-06-01

    For many employees with multiple sclerosis (MS), disclosure of their diagnosis at work is seen as a high-risk strategy that might lead to diminished perceptions of their capabilities by supervisors and colleagues, if not outright discrimination. The consequence of this mistrust surrounding the disclosure process is that employees with MS may leave it until too late to effectively manage symptoms at work. The objective of this paper is to statistically evaluate the relationship between disclosure of diagnosis at work and maintenance of employment. Three annual, large-sample self-report surveys of MS patients prospectively examined the relationship between disclosure of diagnosis at work and employment status. A total of 1438 people responded to all three surveys. Of employed persons in 2010 (n = 946), 673 also responded to the 2012 survey. Of these 673 respondents 564 were still employed. People who had disclosed their MS status to an employer were more likely to remain in employment in Year 3. The effect of disclosure in predicting employment status remained after controlling for age, gender, hours worked and level of disability. This study provides the first empirical support for the positive role of disclosure in maintaining employment status, measured both as job retention and tenure in current employment. © The Author(s) 2013.

  10. Positive predictive value of peptic ulcer diagnosis codes in the Danish National Patient Registry.

    Science.gov (United States)

    Viborg, Søren; Søgaard, Kirstine Kobberøe; Jepsen, Peter

    2017-01-01

    Diagnoses of peptic ulcer are registered in the Danish National Patient Registry (DNPR) for administrative as well as research purposes, but it is unknown whether the coding validity depends on the location of the ulcer. To validate the International Classification of Diseases, 10 th revision diagnosis codes of peptic ulcer in the DNPR by estimating positive predictive values (PPVs) for gastric and duodenal ulcer diagnoses. We identified all patients registered with a hospital discharge diagnosis of peptic ulcer from Aarhus University Hospital, Denmark, in 1995-2006. Among them, we randomly selected 200 who had an outpatient gastroscopy at the time of ulcer diagnosis. We reviewed the findings from these gastroscopies to confirm the presence of peptic ulcer and its location. We calculated PPVs and corresponding 95% confidence intervals (CIs) of gastric and duodenal ulcer diagnoses, using descriptions from the gastroscopic examinations as standard reference. In total, 182 records (91%) were available for review. The overall PPV of peptic ulcer diagnoses in DNPR was 95.6% (95% CI 91.5-98.1), with PPVs of 90.3% (95% CI 82.4-95.5) for gastric ulcer diagnoses, and 94.4% (95% CI 87.4-98.2) for duodenal ulcer diagnoses. PPVs were constant over time. The PPV of uncomplicated peptic ulcer diagnoses in the DNPR is high, and the location of the ulcers is registered correctly in most cases, indicating that the diagnoses are useful for research purposes.

  11. Diagnosis and Fault-Tolerant Control for Thruster-Assisted Position Mooring System

    DEFF Research Database (Denmark)

    Nguyen, Trong Dong; Blanke, Mogens; Sørensen, Asgeir

    2007-01-01

    Development of fault-tolerant control systems is crucial to maintain safe operation of o®shore installations. The objective of this paper is to develop a fault- tolerant control for thruster-assisted position mooring (PM) system with faults occurring in the mooring lines. Faults in line......'s pretension or line breaks will degrade the performance of the positioning of the vessel. Faults will be detected and isolated through a fault diagnosis procedure. When faults are detected, they can be accommodated through the control action in which only parameter of the controlled plant has to be updated...... to cope with the faulty condition. Simulations will be carried out to verify the advantages of the fault-tolerant control strategy for the PM system....

  12. Importance of accurate diagnosis in benign paroxysmal positional vertigo (BPPV) therapy.

    Science.gov (United States)

    Maslovara, Siniša; Vešligaj, Tihana; Butković Soldo, Silva; Pajić-Penavić, Ivana; Maslovara, Karmela; Mirošević Zubonja, Tea; Soldo, Anamarija

    2014-08-01

    To determine the importance of accurate topological diagnostics of the otolith and the differentiation of certain clinical forms of benign paroxysmal positional vertigo (BPPV). A prospective study was conducted at the County General Hospital Vukovar in the period from January 2011 till January 2012. A total of 81 patients with BPPV, 59 females (72.84%) and 22 (27.16%) males (p less than 0.001), mean age 60.1 (± 12.1) were examined. The diagnosis was confirmed and documented by videonystagmography (VNG). The disability due to disease and risk of falling were monitored by filling in the Dizziness Handicap Inventory (DHI) and Activities-specific Balance Confidence Scale (ABC) questionnaires at the beginning and at the end of the repositioning treatment. In 79 (97.3%) patients posterior semicircular canal was affected, and in a small number of patients, two (2.47%) the lateral one. After the repositioning procedures were performed, there was a significant reduction or complete elimination of symptoms in the majority of subjects, 76 (93.82%). The median total DHI sum amounted to 50.5 (± 22.2) at the beginning and 20.4 (± 18.5) at the end of the study (p less than 0.00). Similarly, the results of ABC questionnaires at the beginning of the study demonstrated a result of 59.2% (± 22.4%), and at the end of the treatment the average result of examinees was significantly higher, 84.9% (± 15.2%) (p less than 0.00). Although a subjectively positive Dix-Hallpike or a "supine roll" test is sufficient for the diagnosis of BPPV, it is necessary perform the VNG as well in order to precisely determine the exact localization of the otolith, so that an appropriate repositioning procedure can be applied.

  13. The diagnosis and management of food allergies. Position paper of the Food Allergy Section the Polish Society of Allergology

    Directory of Open Access Journals (Sweden)

    Zbigniew Bartuzi

    2017-10-01

    Full Text Available The paper concerns the current position of the Polish Society of Allergology Food Allergy Section on the diagnosis and management of food allergies. The aim of this position is to provide evidence-based recommendations on the diagnosis and management of patients with allergic hypersensitivity to foods. This position statement includes a systematic review of studies in three areas, namely, the epidemiology, diagnosis and management of food allergies. While taking into account the specific Polish setting, in this publication we also used the current European Academy of Allergy and Clinical Immunology (EAACI position paper and other current position statements, including those of the United States National Institute of Allergy and Infectious Diseases (NIAID.

  14. P A Mini

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. P A Mini. Articles written in Bulletin of Materials Science. Volume 36 Issue 4 August 2013 pp 547-551. Composite supercapacitor electrodes made of activated carbon/PEDOT:PSS and activated carbon/doped PEDOT · T S Sonia P A Mini R Nandhini Kalluri Sujith Balakrishnan ...

  15. Horizontal canal benign paroxysmal positional vertigo: diagnosis and treatment of 37 patients

    Directory of Open Access Journals (Sweden)

    Eliana Teixeira Maranhão

    2015-06-01

    Full Text Available Benign paroxysmal positional vertigo (BPPV, the most frequent cause of vertigo is associated with high morbidity in the elderly population. The most common form is linked to debris in the posterior semicircular canal. However, there has been an increasing number of reported BPPV cases involving the horizontal canals. The purpose of this article is to highlight the clinical features, diagnosis, and treatment in 37 patients with horizontal canal BPPV; twenty-six with geotropic nystagmus, and eleven with the apogeotropic form. Treatment consisted of the Gufoni manoeuver in eighteen patients (48.6%, the barbecue 360° maneuver in twelve patients (32.4%, both manoeuvers in four patients (10.8%, both manoeuvers plus head shaking in one patient (2.7%, and the Gufoni maneuver plus head shaking in two patients. Cupulolithiasis patients were asked to sleep in a forced prolonged position. We obtained a complete resolution of vertigo and nystagmus in 30 patients (81.0% on the initial visit.

  16. Clinical significance of orthostatic dizziness in the diagnosis of benign paroxysmal positional vertigo and orthostatic intolerance.

    Science.gov (United States)

    Jeon, Eun-Ju; Park, Yong-Soo; Park, Shi-Nae; Park, Kyoung-Ho; Kim, Dong-Hyun; Nam, In-Chul; Chang, Ki-Hong

    2013-01-01

    Orthostatic dizziness (OD) and positional dizziness (PD) are considerably common conditions in dizziness clinic, whereas those two conditions are not clearly separated. We aimed to evaluate the clinical significance of simple OD and OD combined with PD for the diagnosis of benign paroxysmal positional vertigo (BPPV) and orthostatic intolerance (OI). Patients presenting with OD (n=102) were divided into two groups according to their symptoms: group PO, presenting with PD as well as OD; group O, presenting with OD. A thorough medical history, physical examination, and vestibular function tests were performed to identify the etiology of the dizziness. Orthostatic vital sign measurement (OVSM) was used to diagnose OI. The majority of patients were in group PO (87.3%). BPPV was the most common cause of OD for entire patients (36.3%) and group PO (37.1%), while OI was most common etiology for group O (38.5%). Total of 17 (16.7%) OI patients were identified by OVSM test. Orthostatic hypotension (n=10) was most frequently found, followed by orthostatic hypertension (n=5), and orthostatic tachycardia (n=2). Group O showed significantly higher percentage (38.5%) of OI than group PO (13.5%) (P=0.039). It is suggested that orthostatic testing such as OVSM or head-up tilt table test should be performed as an initial work up for the patients with simple OD. Positional tests for BPPV should be considered as an essential diagnostic test for patients with OD, even though their dizziness is not associated with PD. Copyright © 2013 Elsevier Inc. All rights reserved.

  17. Association of the position of a hospital-acquired condition diagnosis code with changes in medicare severity diagnosis-related group assignment.

    Science.gov (United States)

    Johnson, Tricia; Kane, Jason M; Odwazny, Richard; McNutt, Robert

    2014-11-01

    Incentives to improve quality include paying less for adverse events, including the Centers for Medicare and Medicaid Services' policy to not pay additionally for events classified as hospital-acquired conditions (HACs). This policy is controversial, as variable coding practices at hospitals may lead to differences in the inclusion and position of HACs in the list of codes used for Medicare Severity Diagnosis-Related Group (MS-DRG) assignment. Evaluate changes in MS-DRG assignment for patients with an HAC and test the association of the position of an HAC in the list of International Classification of Diseases, 9th Revision (ICD-9) diagnosis codes with change in MS-DRG assignment. Retrospective analysis of patients discharged from hospital members of the University HealthSystem Consortium's Clinical Data Base between October 2007 and April 2008. Comparisons were made between the MS-DRG assigned when the HAC was not included in the list of ICD-9 diagnosis codes and the MS-DRG that would have been assigned had the HAC code been included in the assignment. Of the 7027 patients with an HAC, 13.8% changed MS-DRG assignment when the HAC was removed. An HAC in the second position versus third position or lower was associated with a 40-fold increase in the likelihood of MS-DRG change. The position of an HAC in the list of diagnosis codes, rather than the presence of an HAC, is associated with a change in MS-DRG assignment. HACs have little effect on reimbursement unless the HAC is in the second position and patients have minor severity of illness. © 2014 Society of Hospital Medicine.

  18. Mini-mental Parkinson (MMP) as a dementia screening test: comparison with the Mini-Mental State Examination (MMSE).

    Science.gov (United States)

    Larner, Andrew J

    2012-07-01

    As populations age, screening instruments for cognitive impairment and dementia will become of increasing importance in clinical practice. Mini-Mental Parkinson (MMP), a derivative of the Mini-Mental State Examination (MMSE), was originally described as a cognitive screening instrument for use in Parkinson's disease. Its item content addresses some of the acknowledged shortcomings of the MMSE. Pragmatic use of MMP in general cognitive clinics has not previously been examined. To compare the performance of two scales, Mini-Mental Parkinson (MMP) and the Mini-Mental State Examination (MMSE), as cognitive screening instruments for dementia in a memory clinic population. MMP was administered prospectively to 201 consecutive new patient referrals independent of other tests used to establish dementia diagnosis according to standard diagnostic criteria (DSM-IV). Diagnostic utility of MMP for dementia was measured and compared with MMSE. MMP proved easy to use and acceptable to patients. Optimal test accuracy (0.86) was at MMP cutoff of ≤ 17/32, with sensitivity 0.51, specificity 0.97, positive predictive value 0.83, negative predictive value 0.87, and area under Receiver Operating Characteristic curve 0.89. Using a higher cutoff (≤ 29/32), MMP sensitivity was 1.00 with specificity 0.70. MMP scores correlated with MMSE (r = 0.93) and diagnostic agreement was high (κ = 0.85). MMP is a useful screening instrument in the memory clinic setting, with patients who fall below the designated cutoff requiring further investigation to ascertain a cause for their cognitive impairment.

  19. Return of the mini

    International Nuclear Information System (INIS)

    Ashmore, C.

    2001-01-01

    Partly as a result of the contentious nature of some large hydroelectric schemes, and continuing deregulation on a global scale, the mini hydro systems are enjoying unprecedented growth. This article discusses the reasons for the increase in demand for mini hydro systems, and describes Alstom Power Hydro's new, integrated 'water-to-wire' renewable energy solution which is a modular system which integrates the hydro-turbine, generator and controls to provide a single optimised product called the Mini-Aqua. The Mini-Aqua can be supplied inside a turnkey package including all civil works. The company is also looking to the future with development of its Powerformer technology for smaller-scale, grid-connected applications

  20. [Necessity of repeated roll test in horizontal semicircular canalithasis positioned diagnosis].

    Science.gov (United States)

    Lu, H H; Zhao, Y; Chen, T S; Xu, K X; Wang, W; Liu, Q; Wen, C; Li, S S; Li, X J; Han, X; Lin, P

    2016-04-07

    To investigate the influence of repeated roll test in horizontal semicircular canalithasis(HSC-Can) positioned diagnosis, so as to investigate the cecessity of repeated roll test. The patients with a chief complaint of positional vertigo accepted two consecutive cycles roll test, the evoked nystagmus characteristics of each cycle recorded by video-nystagmuograph(VNG), whose direction, intensity, time and other parameters characteristics were analyzed in 51 HSC-Can. Horizontal nystagmus in the same direction with turning were induced in HSC-Can roll test. In 51 HSC-Can, roll test cycle 1 and cycle 2 induced nystagmus same strength side in 26 cases(51.0%), of which 19 cases with stronger nystagmus intensity in cycle 2, another 7 cases were weaker; the opposite strength side of the two loops induced nystagmus, and cycle 1 evoked nystagmus intensity were weaker than cycle 2, based on cycle 2 results determined HSC-Can affected side in 25 cases (49.0%). Lesion and normal side in cycle 1 induced nystagmus duration (x±s, the same below) were (13.4±11.5)s and (14.1±9.9)s, respectively intensity (18.1±22.4)°/s and (13.0±12.0)°/s; as in cycle 2 induced nystagmus duration was (20.7±10.2)s and (18.0±12.0)s, strength respectively(40.4±28.0)°/s and (15.6 ±11.2)°/s. Cycle 2 ipsilateral rotor position evoked nystagmus showed longer duration and stronger intensity than cycle 1. Between two cycle induced ipsilateral nystagmus duration, intensity differences were statistically significant (t values were -4.233 and -5.154, P=0.000). 51 HSC-Can patients, 44 patients selected repositioning maneuver, after 1-2 times of maneuver, 41 cases (93.2%) showed complete resolution of symptoms, all cases's symptoms were improved; other 7 patients selected medication only. The proposed suspicious HSC-Can patients should receive at least two cycles roll test, and mainly in the second cycle could determine the location of the responsible semicircular canals.

  1. Positive predictive value of diagnosis coding for hemolytic anemias in the Danish National Patient Register

    DEFF Research Database (Denmark)

    Hansen, Dennis Lund; Overgaard, Ulrik Malthe; Pedersen, Lars

    2016-01-01

    . Patients with mechanical reason for hemolysis such as an artificial heart valve, and patients with vitamin-B12 or folic acid deficiency were excluded. RESULTS: We identified 412 eligible patients: 249 with a congenital hemolytic anemia diagnosis and 163 with acquired hemolytic anemia diagnosis. In all...

  2. Position of lung scintigraphy in emergency diagnosis and therapeutic indications in cases of severe pulmonary embolism

    International Nuclear Information System (INIS)

    Torquat, Sabine de.

    1975-01-01

    The position of lung scintigraphy in diagnostic strategy is discussed. This technique appears to afford the key examination in severe pulmonary embolism because of its qualities, which are: - speed of execution, - absolute harmlessness, - diagnostic safety. Taking these points in order: - speed of execution is ensured by the very rapid uptake of I 131-labelled albumin macroaggregates (usable immediately) and the existence of the gamma camera; - harmlessness of the examination by the use of non-allergenic radioactive tracers and doses not significantly restricting the vascular bed still perfused; whichever of the two possible techniques is employed (scanner and gamma camera) the examination can always be practised without getting the patient out of bed, which avoids the risk of clot migration due to movement; - certainty of the result by the fact that in the event of a surgical indication the circulation cut-off image is spectacular and obvious in fact a lung amputation image must be equal to or greater than 50% of the pulmonary field before an operation is decided upon all other images remaining within the scope of a hypocoagulant treatment. A study was carried out in a cardio-vascular surgery department on 28 patients hospitalised with a possible view to embolectomy. Lung scintigraphy allows a quick exploration of the minor circulation. In the special clinical situation of the patients, for whom the advisability of an embolectomy is discussed, the scintigraphic examination provides the key: if normal it eliminates the diagnosis absolutely; if not it reveals without extra risk the spectacular obliterations of the vascular bed on which any therapeutic decision, medical or surgical is based [fr

  3. [Validation of the portuguese version of the Mini-Social Phobia Inventory (Mini-SPIN)].

    Science.gov (United States)

    D'El Rey, Gustavo José Fonseca; Matos, Cláudia Wilmor

    2009-01-01

    Social phobia (also known as social anxiety disorder) is a severe mental disorder that brings distress and disability. The aim of this study was validate to the Portuguese language the Mini-Social Phobia Inventory (Mini-SPIN) in a populational sample. We performed a discriminative validity study of the Mini-SPIN in a sample of 644 subjects (Mini-SPIN positive group: n = 218 and control/negative group: n = 426) of a study of anxiety disorders' prevalence in the city of Santo André-SP. The Portuguese version of the Mini-SPIN (with score of 6 points, suggested in the original English version) demonstrated a sensitivity of 95.0%, specificity of 80.3%, positive predictive value of 52.8%, negative predictive value of 98.6% and incorrect classification rate of 16.9%. With score of 7 points, was observed an increase in the specificity and positive predictive value (88.6% and 62.7%), while the sensitivity and negative predictive value (84.8% and 96.2%) remained high. The Portuguese version of the Mini-SPIN showed satisfactory psychometric qualities in terms of discriminative validity. In this study, the cut-off of 7, was considered to be the most suitable to screening of the generalized social phobia.

  4. Optimal Design of the Absolute Positioning Sensor for a High-Speed Maglev Train and Research on Its Fault Diagnosis

    Directory of Open Access Journals (Sweden)

    Junge Zhang

    2012-08-01

    Full Text Available This paper studies an absolute positioning sensor for a high-speed maglev train and its fault diagnosis method. The absolute positioning sensor is an important sensor for the high-speed maglev train to accomplish its synchronous traction. It is used to calibrate the error of the relative positioning sensor which is used to provide the magnetic phase signal. On the basis of the analysis for the principle of the absolute positioning sensor, the paper describes the design of the sending and receiving coils and realizes the hardware and the software for the sensor. In order to enhance the reliability of the sensor, a support vector machine is used to recognize the fault characters, and the signal flow method is used to locate the faulty parts. The diagnosis information not only can be sent to an upper center control computer to evaluate the reliability of the sensors, but also can realize on-line diagnosis for debugging and the quick detection when the maglev train is off-line. The absolute positioning sensor we study has been used in the actual project.

  5. Optimal design of the absolute positioning sensor for a high-speed maglev train and research on its fault diagnosis.

    Science.gov (United States)

    Zhang, Dapeng; Long, Zhiqiang; Xue, Song; Zhang, Junge

    2012-01-01

    This paper studies an absolute positioning sensor for a high-speed maglev train and its fault diagnosis method. The absolute positioning sensor is an important sensor for the high-speed maglev train to accomplish its synchronous traction. It is used to calibrate the error of the relative positioning sensor which is used to provide the magnetic phase signal. On the basis of the analysis for the principle of the absolute positioning sensor, the paper describes the design of the sending and receiving coils and realizes the hardware and the software for the sensor. In order to enhance the reliability of the sensor, a support vector machine is used to recognize the fault characters, and the signal flow method is used to locate the faulty parts. The diagnosis information not only can be sent to an upper center control computer to evaluate the reliability of the sensors, but also can realize on-line diagnosis for debugging and the quick detection when the maglev train is off-line. The absolute positioning sensor we study has been used in the actual project.

  6. HIV Positive Diagnosis During Pregnancy Increases Risk of IPV Postpartum Among Women with No History of IPV in Their Relationship.

    Science.gov (United States)

    Groves, Allison K; Reyes, H Luz McNaughton; Moodley, Dhayendre; Maman, Suzanne

    2017-07-24

    There has been limited study of whether and for whom physical intimate partner violence (IPV) is a consequence of an HIV-positive diagnosis. Per the diathesis stress model, the consequences of HIV infection may be worse for women with a history of IPV. We hypothesize that the positive association between HIV diagnosis in pregnancy and postpartum IPV will be exacerbated for women with a history of IPV. Data come from a prospective cohort study with 1015 participants who completed a baseline antenatal and 9-month postpartum visit. Using logistic regression analyses, we found a statistically significant interaction between HIV diagnosis, history of IPV and postpartum IPV (AOR: 0.40, 95% CI 0.17-0.96). The findings were in the opposite direction as expected: HIV-diagnosis was not associated with IPV for women with a history of IPV (AOR: 2.17, 95% CI 1.06, 4.42). However, HIV-positive women without a history of IPV faced more than two times the risk of incident postpartum IPV than HIV-negative women (AOR: 2.17, 95% CI 1.06, 4.42). Interventions to reduce incident and ongoing IPV during the perinatal period are needed.

  7. Tourette Syndrome: A Mini-Review

    Directory of Open Access Journals (Sweden)

    Michal Novotny

    2018-03-01

    Full Text Available The purpose of this mini-review is to provide the latest information on epidemiology, pathophysiology, diagnosis, and treatment of Tourette syndrome (TS. The authors conducted a literature search of available sources describing the issue of tic disorders with special focus on TS and made a comparison and evaluation of relevant findings. The results of this mini-review indicate that TS is a complex disorder, which has a significant impact on the quality of life of both the patients and his/her family. Therefore, early and proper diagnosis and treatment are necessary in order to reduce or even eliminate both symptoms and social burden of the patient. This requires a multidisciplinary management approach in order to meet the patients’ special needs. Future research should focus on neuroimaging, new neurotransmitter targets, in functional neurosurgery, as well as the effect of non-pharmacological psychotherapies for these people.

  8. MiniDraw

    DEFF Research Database (Denmark)

    2018-01-01

    MiniDraw is a teaching-oriented 2D graphics direct manipulation framework in Java, inspired by JHotDraw. It is used in the book "Flexible, Reliable Software - using Patterns and Agile Development", by Henrik Bærbak Christensen, published by CRC Press 2010.......MiniDraw is a teaching-oriented 2D graphics direct manipulation framework in Java, inspired by JHotDraw. It is used in the book "Flexible, Reliable Software - using Patterns and Agile Development", by Henrik Bærbak Christensen, published by CRC Press 2010....

  9. A web-based delphi study for eliciting helpful criteria in the positive diagnosis of hemophagocytic syndrome in adult patients.

    Science.gov (United States)

    Hejblum, Gilles; Lambotte, Olivier; Galicier, Lionel; Coppo, Paul; Marzac, Christophe; Aumont, Cédric; Fardet, Laurence

    2014-01-01

    The diagnosis of the reactive form of hemophagocytic syndrome in adults remains particularly difficult since none of the clinical or laboratory manifestations are specific. We undertook a study in order to elicit which features constitute helpful criteria for a positive diagnosis. In this Delphi study, the features investigated in the questionnaire and the experts invited to participate in the survey were issued from a bibliographic search. The questionnaire was iteratively proposed to experts via a web-based application with a feedback of the results observed at the preceding Delphi round. Experts were asked to label each investigated criterion in one of the following categories: absolutely required, important, of minor interest, or not assessable in the routine practice environment. A positive consensus was a priori defined as at least 75% answers observed in the categories absolutely required and important. The questionnaire investigated 26 criteria and 24 experts originating from 13 countries participated in the second and final Delphi round. A positive consensus was reached for the nine following criteria: unilineage cytopenia, bicytopenia, pancytopenia, presence of hemophagocytosis pictures on a bone marrow aspirate or on a tissue biopsy, high ferritin level, fever, organomegaly, presence of a predisposing underlying disease, and high level of lactate dehydrogenase. A negative consensus was reached for 13 criteria, and an absence of consensus was observed for 4 criteria. The study constitutes the first initiative to date for defining international guidelines devoted to the positive diagnosis of the reactive form of hemophagocytic syndrome.

  10. The BaBar Mini

    International Nuclear Information System (INIS)

    Brown, David N.

    2003-01-01

    BaBar has recently deployed a new event data format referred to as the Mini. The mini uses efficient packing and aggressive noise suppression to represent the average reconstructed BaBar event in under 7 KBytes. The Mini packs detector information into simple transient data objects, which are then aggregated into roughly 10 composite persistent objects per event. The Mini currently uses Objectivity persistence, and it is being ported to use Root persistence. The Mini contains enough information to support detailed detector studies, while remaining small and fast enough to be used directly in physics analysis. Mini output is customizable, allowing users to both truncate unnecessary content or add content, depending on their needs. The Mini has now replaced three older formats as the primary output of BaBar event reconstruction. A reduced form of the Mini will soon replace the physics analysis format as well, giving BaBar a single, flexible event data format covering all its needs

  11. The BaBar mini

    International Nuclear Information System (INIS)

    Brown, David N.; BaBar Collaboration

    2003-01-01

    BaBar has recently deployed a new event data format referred to as the Mini. The mini uses efficient packing and aggressive noise suppression to represent the average reconstructed BaBar event in under 7 KBytes. The Mini packs detector information into simple transient data objects, which are then aggregated into roughly 10 composite persistent objects per event. The Mini currently uses Objectivity persistence, and it is being ported to use Root persistence. The Mini contains enough information to support detailed detector studies, while remaining small and fast enough to be used directly in physics analysis. Mini output is customizable, allowing users to both truncate unnecessary content or add content, depending on their needs. The Mini has now replaced three older formats as the primary output of BaBar event reconstruction. A reduced form of the Mini will soon replace the physics analysis format as well, giving BaBar a single, flexible event data format covering all its needs

  12. Mini mental state examination

    DEFF Research Database (Denmark)

    Kørner, Ejnar Alex; Lauritzen, Lise; Wang, August

    2008-01-01

    INTRODUCTION: The Mini Mental State Examination (MMSE) is widely used in Denmark, but often in non-validated versions. In 2000 a cross-sectional workgroup decided on a new common version of the MMSE with a corresponding manual, which is validated for the first time in the present study. MATERIALS...... the severity of dementia disorders. Udgivelsesdato: 2008-Feb-25...

  13. Berkeley mini-collider

    International Nuclear Information System (INIS)

    Schroeder, L.S.

    1984-06-01

    The Berkeley Mini-Collider, a heavy-ion collider being planned to provide uranium-uranium collisions at T/sub cm/ less than or equal to 4 GeV/nucleon, is described. The central physics to be studied at these energies and our early ideas for a collider detector are presented

  14. Diagnosis and treatment of hypoparathyroidism: a position statement from the Brazilian Society of Endocrinology and Metabolism.

    Science.gov (United States)

    Maeda, Sergio Setsuo; Moreira, Carolina Aguiar; Borba, Victória Zeghbi Cochenski; Bandeira, Francisco; Farias, Maria Lucia Fleiuss de; Borges, João Lindolfo Cunha; Paula, Francisco José Albuquerque de; Vanderlei, Felipe Augusto Brasileiro; Montenegro, Fábio Luiz de Menezes; Santos, Rodrigo Oliveira; Ferraz-de-Souza, Bruno; Lazaretti-Castro, Marise

    2018-02-01

    Objective To present an update on the diagnosis and treatment of hypoparathyroidism based on the most recent scientific evidence. Materials and methods The Department of Bone and Mineral Metabolism of the Sociedade Brasileira de Endocrinologia e Metabologia (SBEM; Brazilian Society of Endocrinology and Metabolism) was invited to prepare a document following the rules set by the Guidelines Program of the Associação Médica Brasileira (AMB; Brazilian Medical Association). Relevant papers were retrieved from the databases MEDLINE/PubMed, LILACS, and SciELO, and the evidence derived from each article was classified into recommendation levels according to scientific strength and study type. Conclusion An update on the recent scientific literature addressing hypoparathyroidism is presented to serve as a basis for the diagnosis and treatment of this condition in Brazil.

  15. Comparison between McMaster and Mini-FLOTAC methods for the enumeration of Eimeria maxima oocysts in poultry excreta.

    Science.gov (United States)

    Bortoluzzi, C; Paras, K L; Applegate, T J; Verocai, G G

    2018-04-30

    Monitoring Eimeria shedding has become more important due to the recent restrictions to the use of antibiotics within the poultry industry. Therefore, there is a need for the implementation of more precise and accurate quantitative diagnostic techniques. The objective of this study was to compare the precision and accuracy between the Mini-FLOTAC and the McMaster techniques for quantitative diagnosis of Eimeria maxima oocyst in poultry. Twelve pools of excreta samples of broiler chickens experimentally infected with E. maxima were analyzed for the comparison between Mini-FLOTAC and McMaster technique using, the detection limits (dl) of 23 and 25, respectively. Additionally, six excreta samples were used to compare the precision of different dl (5, 10, 23, and 46) using the Mini-FLOTAC technique. For precision comparisons, five technical replicates of each sample (five replicate slides on one excreta slurry) were read for calculating the mean oocyst per gram of excreta (OPG) count, standard deviation (SD), coefficient of variation (CV), and precision of both aforementioned comparisons. To compare accuracy between the methods (McMaster, and Mini-FLOTAC dl 5 and 23), excreta from uninfected chickens was spiked with 100, 500, 1,000, 5,000, or 10,000 OPG; additional samples remained unspiked (negative control). For each spiking level, three samples were read in triplicate, totaling nine reads per spiking level per technique. Data were transformed using log10 to obtain normality and homogeneity of variances. A significant correlation (R = 0.74; p = 0.006) was observed between the mean OPG of the McMaster dl 25 and the Mini-FLOTAC dl 23. Mean OPG, CV, SD, and precision were not statistically different between the McMaster dl 25 and Mini-FLOTAC dl 23. Despite the absence of statistical difference (p > 0.05), Mini-FLOTAC dl 5 showed a numerically lower SD and CV than Mini-FLOTAC dl 23. The Pearson correlation coefficient revealed significant and positive

  16. Significant changes in sexual behavior after a diagnosis of human papillomavirus-positive and human papillomavirus-negative oral cancer.

    Science.gov (United States)

    Taberna, Miren; Inglehart, Ronald C; Pickard, Robert K L; Fakhry, Carole; Agrawal, Amit; Katz, Mira L; Gillison, Maura L

    2017-04-01

    Sexual behavior and oral human papillomavirus (HPV) infection are risk factors for oral squamous cell carcinoma (OSCC). The effects of OSCC diagnosis and treatment on subsequent relationship stress and sexual behavior are unknown. Incident cases of HPV-positive or HPV-negative OSCC in patients who had a partnered relationship and partners of patients with oropharyngeal cancer were eligible for a study in which surveys were administered at diagnosis and at the 6-month follow-up time point to assess relationship distress, HPV transmission and concerns about health consequences, and sexual behavior. The frequency distributions of responses, stratified by tumor HPV status, were compared at baseline and follow-up. In total, 262 patients with OSCC and 81 partners were enrolled. Among the patients, 142 (54.2%) had HPV-positive OSCC, and 120 (45.8%) had HPV-negative OSCC. Relationship distress was infrequently reported, and 69% of patients felt that their relationship had strengthened since the cancer diagnosis. Both HPV-positive patients (25%) and their partners (14%) reported feelings of guilt or responsibility for the diagnosis of an HPV-caused cancer. Concern over sexual, but not nonsexual, HPV transmission to partners was reported by 50%. Significant declines in the frequency of vaginal and oral sexual behaviors were reported at follow-up, regardless of tumor HPV status. From baseline to 6 months, significant increases in abstinence from vaginal sex (from 10% to 34%; P oral sex (from 25% to 80%; P oral sex, regardless of tumor HPV status. Sexual behavior is an important quality-of-life outcome to assess within clinical trials. [See related editorial on pages 000-000, this issue.] Cancer 2017. © 2017 American Cancer Society. Cancer 2017;123:1156-1165. © 2016 American Cancer Society. © 2017 American Cancer Society.

  17. Diagnostic validity Polish language version of the questionnaire MINI-KID (Mini International Neuropsychiatry Interview for Children and Adolescent).

    Science.gov (United States)

    Adamowska, Sylwia; Sylwia, Adamowska; Adamowski, Tomasz; Tomasz, Adamowski; Frydecka, Dorota; Dorota, Frydecka; Kiejna, Andrzej; Andrzej, Kiejna

    2014-10-01

    Since over forty years structuralized interviews for clinical and epidemiological research in child and adolescent psychiatry are being developed that should increase validity and reliability of diagnoses according to classification systems (DSM and ICD). The aim of the study is to assess the validity of the Polish version of MINI-KID (Mini International Neuropsychiatric Interview for Children and Adolescents) in comparison to clinical diagnosis made by a specialist in the field of child and adolescent psychiatry. There were 140 patients included in the study (93 boys, 66.4%, mean age 11.8±3.0 and 47 girls 33.5%, mean age 14.0±2.9). All the patients were diagnosed by the specialist in the field of child and adolescent psychiatry according to ICD-10 criteria and by the independent interviewer with the Polish version of MINI-KID (version 2.0, 2001). There was higher agreement between clinical diagnoses and diagnoses based on MINI-KID interview with respect to eating disorders and externalizing disorders (κ 0.43-0.56) and lower in internalizing disorders (κ 0.13-0.45). In the clinical interview, there was smaller number of diagnostic categories (maximum 3 diagnoses per one patient) in comparison to MINI-KID (maximum 10 diagnoses per one patient), and the smaller percentage of patients with one diagnosis (65,7%) in comparison to MINI-KID interview (72%). Our study has shown satisfactory validity parameters of MINI-KID questionnaire, promoting its use for clinical and epidemiological settings. The Mini International Neuropsychiatry Interview for Children and Adolescent (MINI-KID) is the first structuralized diagnostic interview for assessing mental status in children and adolescents, which has been translated into Polish language. Our validation study demonstrated satisfactory psychometric properties of the questionnaire, enabling its use in clinical practice and in research projects. Copyright © 2014 Elsevier Inc. All rights reserved.

  18. Pulmonary aspergilloma: A rare differential diagnosis to lung cancer after positive FDG PET scan

    Directory of Open Access Journals (Sweden)

    Franziska Spycher

    2014-01-01

    Full Text Available Early diagnosis and treatment of lung cancer, one of the leading causes of cancer-related death, is important to improve morbidity and mortality. Therefore any suspect solitary pulmonary nodule should prompt the pursuit for a definitive histological diagnosis. We describe the case of a 55-years-old male ex-smoker, who was admitted to our hospital due to recurrent hemoptysis and dry cough. A CT scan showed an irregular nodule of increasing size (28 mm in diameter in the left lower lobe (LLL. A whole body PET-CT scan (643 MBq F-18 FDG i.v. was performed and confirmed an avid FDG uptake of the nodule in the LLL, highly suspicious of lung cancer, without any evidence of lymphogenic or hematogenic metastasis. Bronchoscopy was not diagnostic and due to severe adhesions after prior chest trauma and the central location of the nodule, a lobectomy of the LLL was performed. Surprisingly, histology showed a simple aspergilloma located in a circumscribed bronchiectasis with no evidence of malignancy. This is a report of an informative example of an aspergilloma, which presented with symptoms and radiological features of malignant lung cancer.

  19. TMJ ARTICULAR DISC POSITION AND CONFIGURATION 30 YEARS AFTER INITIAL DIAGNOSIS OF INTERNAL DERANGEMENT

    NARCIS (Netherlands)

    DELEEUW, R; BOERING, G; STEGENGA, B; DEBONT, LGM

    Purpose: This study evaluates disc position and configuration on magnetic resonance imaging (MRI) in temporomandibular joints (TMJs) with a long history of internal derangement. Patients and Methods: Sagittal T1-weighted MRIs of 55 TMJs that were diagnosed with internal derangement approximately 30

  20. Distinct trajectories of positive and negative affect after colorectal cancer diagnosis

    NARCIS (Netherlands)

    Ciere, Yvette; Janse, Moniek; Almansa, Josué; Visser, Annemieke; Sanderman, Robbert; Sprangers, Mirjam A.G.; Ranchor, Adelita V.; Fleer, Joke

    2017-01-01

    Objective: Insight into trajectories of positive affect (PA) and negative affect (NA) across the cancer continuum may improve understanding of the nature of adjustment problems. The primary aim of this study was to identify subgroups of patients with distinct trajectories of PA and NA following

  1. Distinct Trajectories of Positive and Negative Affect After Colorectal Cancer Diagnosis

    NARCIS (Netherlands)

    Ciere, Yvette; Janse, Moniek; Almansa, Josué; Visser, Annemieke; Sanderman, Robbert; Sprangers, Mirjam A G; Ranchor, Adelita V; Fleer, Joke

    OBJECTIVE: Insight into trajectories of positive affect (PA) and negative affect (NA) across the cancer continuum may improve understanding of the nature of adjustment problems. The primary aim of this study was to identify subgroups of patients with distinct trajectories of PA and NA following

  2. Usefulness of gastroesophageal reflux scintigraphy using the knee-chest position for the diagnosis of gastroesophageal reflux disease

    International Nuclear Information System (INIS)

    Asakura, Yasushi; Imai, Yukinori; Ota, Shinichi; Fujiwara, Kenji; Miyamae, Tatsuya

    2005-01-01

    The aim of this study is to evaluate the usefulness of gastroesophageal reflux (GER) scintigraphy using the knee-chest (KC) position for the diagnosis of gastroesophageal reflux disease (GERD). The study subjects were 37 patients with GERD and 8 healthy volunteers (control group). Endoscopically observed esophageal mucosal breaks were evaluated with the Los Angeles classification. For GER scintigraphy, the subjects ingested liquid yogurt labeled with 99m Tc-diethylene triamine pentaacetic acid ( 99m Tc-DTPA) and water. Imaging was performed in the supine and KC position, and GER was graded as 1-4 according to the extent of GER assessed by scintigraphy. GER scintigraphy revealed no reflux in the control group (specificity: 100%). In the supine position, gastroesophageal reflux was observed in 49% of the patients with GERD, compared to 76% in the KC position. 21 of 23 (91%) patients with erosive esophagitis were shown to have GER with scintigraphy. GER scintigraphy revealed severe reflux (grade 3 or 4) (83%, 10/12) in the patients who had severe mucosal breaks (the Los Angels classification grade C or D). GER scintigraphy detected grade 1 or 2 reflux in 7 of the 14 patients who were endoscopically negative. There was a correlation between the endoscopically determined severity of mucosa and the reflux grade which was determined with GER scintigraphy. GER scintigraphy can detect gastroesophageal reflux with a high sensitivity in the KC position and might be a useful method in the screening and assessment of the severity of this disease. This method would be useful for the diagnosis of GERD in endoscopically negative patients. (author)

  3. Diagnosis and Management of Paediatric Autoimmune Liver Disease: ESPGHAN Hepatology Committee Position Statement.

    Science.gov (United States)

    Mieli-Vergani, Giorgina; Vergani, Diego; Baumann, Ulrich; Czubkowski, Piotr; Debray, Dominique; Dezsofi, Antal; Fischler, Björn; Gupte, Girish; Hierro, Loreto; Indolfi, Giuseppe; Jahnel, Jörg; Smets, Françoise; Verkade, Henkjan J; Hadzic, Nedim

    2017-11-03

    Paediatric autoimmune liver disease is characterised by inflammatory liver histology, circulating autoantibodies and increased levels of IgG, in the absence of a known etiology. Three conditions have a likely autoimmune pathogenesis: autoimmune hepatitis (AIH), autoimmune sclerosing cholangitis (ASC), and de novo AIH after liver transplantation. Two types of paediatric AIH are recognized according to seropositivity for smooth muscle and/or antinuclear antibody (SMA/ANA, AIH-1) or liver kidney microsomal type 1 and/or anti-liver cytosol type 1 antibodies (anti-LKM-1/anti-LC-1; AIH-2).Pertinent issues addressing the diagnosis, treatment and long term follow up were formulated by a core group of ESPGHAN members. They have commissioned the first authors with execution of this project. Initially, they have performed a systematic literature search on MEDLINE, ResearchGate and Mendeley databases over the last 30 years and produced a document focusing on prospective and retrospective studies in children. The ESPGHAN core group and ESPGHAN Hepatology Committee members voted on each recommendation, using a formal voting technique.

  4. Evaluation of the 2007 WHO guideline to improve the diagnosis of tuberculosis in ambulatory HIV-positive adults.

    Science.gov (United States)

    Koole, Olivier; Thai, Sopheak; Khun, Kim Eam; Pe, Reaksmey; van Griensven, Johan; Apers, Ludwig; Van den Ende, Jef; Mao, Tan Eang; Lynen, Lutgarde

    2011-04-06

    In 2007 WHO issued a guideline to improve the diagnosis of smear-negative and extrapulmonary tuberculosis (EPTB) in HIV-positive patients. This guideline relies heavily on the acceptance of HIV-testing and availability of chest X-rays. Cohort study of TB suspects in four tuberculosis (TB) clinics in Phnom Penh, Cambodia. We assessed the operational performance of the guideline, the incremental yield of investigations, and the diagnostic accuracy for smear-negative tuberculosis in HIV-positive patients using culture positivity as reference standard. 1,147 (68.9%) of 1,665 TB suspects presented with unknown HIV status, 1,124 (98.0%) agreed to be tested, 79 (7.0%) were HIV-positive. Compliance with the guideline for chest X-rays and sputum culture requests was 97.1% and 98.3% respectively. Only 35 of 79 HIV-positive patients (44.3%) with a chest X-ray suggestive of TB started TB treatment within 10 days. 105 of 442 HIV-positive TB suspects started TB treatment (56.2% smear-negative pulmonary TB (PTB), 28.6% smear-positive PTB, 15.2% EPTB). The median time to TB treatment initiation was 5 days (IQR: 2-13 days), ranging from 2 days (IQR: 1-11.5 days) for EPTB, over 2.5 days (IQR: 1-4 days) for smear-positive PTB to 9 days (IQR: 3-17 days) for smear-negative PTB. Among the 34 smear-negative TB patients with a confirmed diagnosis, the incremental yield of chest X-ray, clinical suspicion or abdominal ultrasound, and culture was 41.2%, 17.6% and 41.2% respectively. The sensitivity and specificity of the algorithm to diagnose smear-negative TB in HIV-positive TB suspects was 58.8% (95%CI: 42.2%-73.6%) and 79.4% (95%CI: 74.8%-82.4%) respectively. Pending point-of-care rapid diagnostic tests for TB disease, diagnostic algorithms are needed. The diagnostic accuracy of the 2007 WHO guideline to diagnose smear-negative TB is acceptable. There is, however, reluctance to comply with the guideline in terms of immediate treatment initiation.

  5. Evaluation of the 2007 WHO guideline to improve the diagnosis of tuberculosis in ambulatory HIV-positive adults.

    Directory of Open Access Journals (Sweden)

    Olivier Koole

    Full Text Available BACKGROUND: In 2007 WHO issued a guideline to improve the diagnosis of smear-negative and extrapulmonary tuberculosis (EPTB in HIV-positive patients. This guideline relies heavily on the acceptance of HIV-testing and availability of chest X-rays. METHODS AND FINDINGS: Cohort study of TB suspects in four tuberculosis (TB clinics in Phnom Penh, Cambodia. We assessed the operational performance of the guideline, the incremental yield of investigations, and the diagnostic accuracy for smear-negative tuberculosis in HIV-positive patients using culture positivity as reference standard. 1,147 (68.9% of 1,665 TB suspects presented with unknown HIV status, 1,124 (98.0% agreed to be tested, 79 (7.0% were HIV-positive. Compliance with the guideline for chest X-rays and sputum culture requests was 97.1% and 98.3% respectively. Only 35 of 79 HIV-positive patients (44.3% with a chest X-ray suggestive of TB started TB treatment within 10 days. 105 of 442 HIV-positive TB suspects started TB treatment (56.2% smear-negative pulmonary TB (PTB, 28.6% smear-positive PTB, 15.2% EPTB. The median time to TB treatment initiation was 5 days (IQR: 2-13 days, ranging from 2 days (IQR: 1-11.5 days for EPTB, over 2.5 days (IQR: 1-4 days for smear-positive PTB to 9 days (IQR: 3-17 days for smear-negative PTB. Among the 34 smear-negative TB patients with a confirmed diagnosis, the incremental yield of chest X-ray, clinical suspicion or abdominal ultrasound, and culture was 41.2%, 17.6% and 41.2% respectively. The sensitivity and specificity of the algorithm to diagnose smear-negative TB in HIV-positive TB suspects was 58.8% (95%CI: 42.2%-73.6% and 79.4% (95%CI: 74.8%-82.4% respectively. CONCLUSIONS: Pending point-of-care rapid diagnostic tests for TB disease, diagnostic algorithms are needed. The diagnostic accuracy of the 2007 WHO guideline to diagnose smear-negative TB is acceptable. There is, however, reluctance to comply with the guideline in terms of immediate treatment

  6. Interval between injection of contrast material and positive contrast cheliography affects accurate diagnosis of diaphragmatic hernia

    Directory of Open Access Journals (Sweden)

    Ismail A. Sen

    2015-01-01

    Full Text Available The aim of this study was to evaluate the clinical, surgical and diagnostic imaging findings in 11 cats and 3 dogs with suspected acute and chronic traumatic diaphragmatic hernia, and to compare the results of positive contrast cheliography (peritoneography taken immediately and 5 min after the injection of contrast material. Thoracic and abdominal radiography, ultrasonography, and positive contrast cheliography of all animals were performed. Eight cases were considered as acute and six cases were considered chronic. The contrast images taken immediately after the injection of contrast material revealed the contrast material in the thoracic cavity in 8/8 acute trauma patients, but in none of the chronic cases. In 5/6 of these cases contrast material was seen in the thoracal cavity only in additional images taken after 5 min. One patient was diagnosed with FIP and excluded from the study. Twelve cases had complete resolution and one animal died during the early postoperative period. Our results suggest that positive contrast cheliography performed immediately after the injection of contrast material may not reveal chronic cases of diaphragmatic hernia and a second imaging (or imaging after 5 min is indicated in order not to overlook chronic cases.

  7. Mini-FLOTAC and Kato-Katz: helminth eggs watching on the shore of Lake Victoria.

    Science.gov (United States)

    Barda, Beatrice; Zepherine, Henry; Rinaldi, Laura; Cringoli, Giuseppe; Burioni, Roberto; Clementi, Massimo; Albonico, Marco

    2013-07-31

    One of the challenges for monitoring helminth control programmes based on preventive chemotherapy is the lack of a copro-parasitological gold-standard method that combines good sensitivity with quantitative performance, low cost, and easy-to-learn technique.The aim of our study was to evaluate and compare, the WHO recommended quantitative diagnostic technique (Kato-Katz) and the Mini-FLOTAC. Mini-FLOTAC is an innovative method based on floatation of helminths eggs with two different solutions (FS2 and FS7) using a close system (Fill-FLOTAC) with 5% fixative. Kato-Katz was performed following WHO recommendation. The study was carried out in a rural part of Tanzania, close to Lake Victoria, where the laboratory facilities are fairly scarce, and the basic technique used in the local laboratory (direct smear) was taken as reference standard. 201 children were screened for intestinal helminths and 91% of them were found to be positive. The agreement among the three techniques was calculated with k Cohen coefficient and was fairly good (k = 0.4), although the Mini-FLOTAC results were more sensitive for hookworm (98%) with FS2, and for S.mansoni (90%) with FS7 followed by Kato-Katz (91% and 60% respectively) and direct smear (30% and 10% respectively). A good agreement was found between Mini-FLOTAC and Kato-Katz (k = 0.81) with FS7 (k = 0.76) for hookworm diagnosis and a fairly good one for S.mansoni diagnosis (k = 0.5). For both infections we had a poor agreement between the two quantitative techniques and the direct smear (kMcMaster) and in different settings where other soil-transmitted helminths are also endemic.

  8. Dual diagnosis vs. triple diagnosis in HIV: a comparative study to evaluate the differences in psychopathology and suicidal risk in HIV positive male subjects.

    Science.gov (United States)

    Gupta, M; Kumar, K; Garg, P D

    2013-12-01

    The problem of triple diagnosis of HIV, substance abuse and psychiatric disorders is a complex one with difficult solutions. HIV disease progression is affected by substance use as well as psychiatric illness burden due to both direct as well as indirect factors. Continuing substance abuse with poor drug adherence coexists with psychiatric disorders leading to increased morbidity and mortality. A total of 100 HIV positive subjects comprising of two groups each having 50 subjects with and without substance abuse were assessed using detailed history, mental state examination, WHO schedule for clinical assessment in neuropsychiatry (SCAN 2.0) and Beck's Scale for Suicidal Ideation (BSS). Statistical analysis used Chi-Square test, Fischer's exact test, Student's t-test, Pearson's correlation coefficient, univariate and multiple regression analysis, univariate and multiple logistic regression analysis. p-Valueabuse, as compared to subjects without substance use. Suicidal risk was significantly increased (pabuse did not increase the risk. Substance abuse inflicts a much greater burden on HIV positive individuals as compared to subjects without substance use. Concomitant substance abuse resulted in significantly increased duration of illness and psychiatric morbidity. Copyright © 2013 Elsevier B.V. All rights reserved.

  9. Comparison of shoulder positions at MR arthrography: change of labroligamentous complex shape and diagnosis of labral tears

    International Nuclear Information System (INIS)

    Kwak, Jin Young; Ha, Doo Hoe; Kim, Jeung Sook; Lee, Young Soo

    2001-01-01

    To compare the neutral, internal, and external rotation positions of the glenohumeral joint during magnetic resonance (MR) arthrography performed to assess changes in the shape of the labroligamentous complex (LLC) and in the labral tear. MR arthrography of the shoulder was retrospectively evaluated in 36 patients aged 14-66 (mean, 40) years. Fourteen cases were confirmed by arthroscopic surgery (7 SLAP lesions, 2 Bankart lesions, 1 both SLAP and Bankart lesions). Axial fat-suppressed T1-weighted spin-echo images were acquired with each shoulder in the neutral position, and with internal and external rotations. In each position, we measured the angle of rotation between the perpendicular line on the glenoid fossa and the long axis of the humeral head, analyzing the relationship between the rotational angle and changes in the shape of the LLC at each internal and external rotation, relative to the neutral position. In addition, labral tears in 14 arthroscopically confirmed joints were evaluated in each position. Mean angles of rotation relative to the neutral position were 44.1 and 45.3 degrees in internal and external rotation, respectively. Changes in the anterior LLC occurred in 25 and 24 cases of internal and external rotation, respectively. There was a significantly meaningful relationship between rotational angle and changes in the shape of the anterior LLC during external rotation, and when this changes was noticed, the rotational angle was wider (p<0.05). The posterior LLC changed in shape in 13 and 16 cases of internal and external rotation, respectively, but changes according to the angle of rotation were not statistically significant. In arthroscopically confirmed joints, diagnosis of the eight SLAP lesions at external rotation tended to become more accurate, but no statistically significant differences were noted (p=0.07). Two Bankart lesions were interpreted as a tear in all three positions, and one other such lesion was interpreted as a tear in the

  10. Feelings of Women With Strong Family Histories Who Subsequent to Their Breast Cancer Diagnosis Tested BRCA Positive.

    Science.gov (United States)

    Joseph, Meera; Rab, Faiza; Panabaker, Karen; Nisker, Jeff

    2015-05-01

    Family physicians in Canada as reported in several studies do not recognize the importance of family history in relation to breast/ovarian cancer and thus Canadian women with strong family histories continue to develop early-onset breast cancer without the knowledge of or ability to make choices regarding increased surveillance or preventative strategies. This study explored the feelings of women who learned about their hereditary risk only after their diagnosis younger than 52 years and who eventually tested positive for a BRCA gene mutation. Thirty-four such women were mailed an invitation to participate in this research including a letter of information, consent form, and discussion prompts for their written narrative response. Rigorous mixed method analyses were performed using Charmaz-based qualitative analyses as well as quantitative analyses. Thirteen women (38.2%) responded with narratives for qualitative analysis from which 4 themes were coconstructed as follows: I, types of emotions; II, emotional response; III, coping with emotions; and IV, advice to women at similar risk. Women felt they should have learned about their hereditary risk from their family physician and through public education before their diagnosis. Although not experienced at the time of diagnosis, anger, frustration, and regret were experienced after receiving their BRCA results. These emotions arose from our research participants' lack of opportunity for prior genetic counseling and testing opportunity for genetic counseling and testing. With increased public and physician education, it is hoped that women with significant family histories of breast/ovarian cancer will be identified before diagnosis and given options regarding cancer surveillance and risk reduction strategies.

  11. Mini Project Programming Exams

    DEFF Research Database (Denmark)

    Nørmark, Kurt; Thomsen, Lone Leth; Torp, Kristian

    2008-01-01

    A number of different types of final programming exams used or considered at the Department of Computer Science, Aalborg University, are identified and analyzed. Based on this analysis, a new type of programming exam is introduced called a Mini Project Programming (MIP) exam. MIP is a group...... years. The MIP exam is a compromise between (1) a long problem-based project exam and (2) a short oral or written programming exam. It is concluded that the strengths of MIP are the high degree of realism in the exam assignment and comprehensiveness relative to the course syllabus. The main challenge...

  12. DIAGNOSIS OF CULTURE POSITIVE URINARY TRACT INFECTIONS AND THEIR ANTIMICROBIAL SENSITIVITY PROFILE IN TERTIARY CARE CENTRE

    Directory of Open Access Journals (Sweden)

    Prince Sreekumar Pius

    2016-12-01

    Full Text Available BACKGROUND Urinary tract infection is very common all over the world and in India more than 10 million cases are reported per year. It is one of the common infections diagnosed in the outpatients as well as the hospitalised patients. Empirical treatment of community acquired urinary tract infections are determined by the antibiotic sensitivity in a population. This study was conducted to determine the antimicrobial sensitivity amongst the uropathogens to help establish local guidelines on treatment of urinary tract infection. MATERIALS AND METHODS In this study, we collected 1306 samples from patients in whom we suspected to have urinary tract infection based on clinical signs and symptoms (e.g. with fever (greater than 38°C without another explanation or from a patient who had at least one urinary symptom (dysuria, urgency, frequency, or suprapubic pain or tenderness in our hospital during January 2016-June 2016. RESULTS Urine cultures were positive for 18% of the patients. Among these cultures, Klebsiella pneumonia (41%, Escherichia coli (35% and Pseudomonas aeruginosa (7% were the common organisms found. Highest antimicrobial sensitivity amongst these pathogens was found with cefoperazone/sulbactam and amikacin. CONCLUSION Cefoperazone/sulbactam and amikacin were the highly sensitive systemic antibiotics while ciprofloxacin and norfloxacin were the sensitive oral antibiotics in our locality.

  13. DETECTION OF MYCOBACTERIUM TUBERCULOSIS IN BLOOD FOR DIAGNOSIS OF GENERALISED TUBERCULOSIS IN HIV-POSITIVE PATIENTS

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    V. N. Zimina

    2017-01-01

    Full Text Available Objective: To study the informative value of the detection of mycobacteria in blood with the cultural method in patients with suspected tuberculous sepsis and to determine the most significant clinical and laboratory criteria for testing. Materials and methods: The investigation to detect M.tuberculosis was fulfilled in 159 HIV-positive patients with suspected tuberculosis sepsis. Blood culture was completed with culture medium Myco/F Lytic Culture Vials and analyzer BACTEC 9050. Results: Mycobacteria were detected in blood of 19 patients (11,9% of all patients: in 18 patients the growth of М. tuberculosis complex was detected (25,3% of all patients with diagnosed tuberculosis and in 1 patient it was Mycobacterium avium complex (0,6% of all patients. It was shown, that the probability of M.tuberculosis detection was especially associated with the severity of the disease, immunosupression (less than 100 cells/mkl, hemoglobin quantity less than 90 g/l (levels were determined through the seeking for the most significant cutoffs. It was not proofed, that meningoencephalitis develops more often in patients with proven bacteremia. There were no evident differences in detection frequency of mycobacteria in sputum between patients with tuberculous sepsis and without it.

  14. Positive predictive value and impact of misdiagnosis of a heart failure diagnosis in administrative registers among patients admitted to a University Hospital cardiac care unit

    DEFF Research Database (Denmark)

    Mard, Shan; Nielsen, Finn Erland

    2010-01-01

    To evaluate the positive predictive value (PPV) of a diagnosis of heart failure (HF) in the Danish National Registry of Patients (NRP) among patients admitted to a University Hospital cardiac care unit, and to evaluate the impact of misdiagnosing HF.......To evaluate the positive predictive value (PPV) of a diagnosis of heart failure (HF) in the Danish National Registry of Patients (NRP) among patients admitted to a University Hospital cardiac care unit, and to evaluate the impact of misdiagnosing HF....

  15. Top Differential Diagnosis Should Be Microscopic Polyangiitis in ANCA-Positive Patient with Diffuse Pulmonary Hemorrhage and Hemosiderosis

    Directory of Open Access Journals (Sweden)

    Nicholas D. Ward

    2014-01-01

    Full Text Available A rat model of antineutrophil cytoplasmic antibody (ANCA associated vasculitides reveals crescentic glomerulonephritis as seen in human renal biopsies and diffuse lung hemorrhage that is not well documented in human lung biopsies. A 64-year-old male, with shortness of breath and mild elevation of serum creatinine, was found to have a positive serum test for ANCA, but negative antiglomerular basement membrane antibody. A renal biopsy showed pauci-immune type of crescentic glomerulonephritis and focal arteritis. The prior lung wedge biopsy was retrospectively reviewed to show diffuse hemorrhage and hemosiderosis with focal giant cells. In addition, small arteries revealed subtle neutrophil aggregation, and margination along vascular endothelium, but no definitive vasculitis. The pathology of ANCA associated vasculitides results from activated neutrophils by ANCA and subsequent activation of the alternative complement cascade with endothelial injury, neutrophil aggregation and margination. Our findings, after the correlation between lung biopsy and renal biopsy, imply that the top differential diagnosis in the lung biopsy should be microscopic polyangiitis when diffuse pulmonary hemorrhage and hemosiderosis are present in this ANCA-positive patient.

  16. Moderating effects of sex on the impact of diagnosis and amyloid positivity on verbal memory and hippocampal volume.

    Science.gov (United States)

    Caldwell, Jessica Z K; Berg, Jody-Lynn; Cummings, Jeffrey L; Banks, Sarah J

    2017-09-12

    Alzheimer's disease (AD) impacts men and women differently, but the effect of sex on predementia stages is unclear. The objective of this study was to examine whether sex moderates the impact of florbetapir positron emission tomography (PET) amyloid positivity (A + ) on verbal learning and memory performance and hippocampal volume (HV) in normal cognition (NC) and early mild cognitive impairment (eMCI). Seven hundred forty-two participants with NC and participants with eMCI from the Alzheimer's Disease Neuroimaging Initiative (second cohort [ADNI2] and Grand Opportunity Cohort [ADNI-GO]) were included. All had baseline florbetapir PET measured, and 526 had screening visit HV measured. Regression moderation models were used to examine whether A + effects on Rey Auditory Verbal Learning Test learning and delayed recall and right and left HV (adjusted for total intracranial volume) were moderated by diagnosis and sex. Age, cognition at screening, education, and apolipoprotein E ε4 carrier status were controlled. Women with A + , but not those with florbetapir PET amyloid negative (A-),eMCI showed poorer learning. For women with NC, there was no relationship of A + with learning. In contrast, A + men trended toward poorer learning regardless of diagnosis. A similar trend was found for verbal delayed recall: Women with A + , but not A-, eMCI trended toward reduced delayed recall; no effects were observed for women with NC or for men. Hippocampal analyses indicated that women with A + , but not those with A - , eMCI, trended toward smaller right HV; no significant A + effects were observed for women with NC. Men showed similar, though nonsignificant, patterns of smaller right HV in A + eMCI, but not in men with A - eMCI or NC. No interactive effects of sex were noted for left HV. Women with NC showed verbal learning and memory scores robust to A + , and women with A + eMCI lost this advantage. In contrast, A + impacted men's scores less significantly or not at all, and

  17. Estimation of the frequency of positive biopsies for cancer in patients with diagnosis by images of breast lesion BIRADS 3, Hospital Mexico, 2007-2009

    International Nuclear Information System (INIS)

    Obando Valverde, Aiza

    2013-01-01

    The histopathological findings have been described in patients with diagnosis by images of BIRADS 3, at the Hospital Mexico during the years 2007-2009. The histopathological findings have enrolled patients with diagnosis by images of lesion probably benign. The percentage of positive biopsies for cancer in patients BIRADS 3 was determined and compared the finding, with data found in the international literature. The stadium has been determined at the time of positive histopathological diagnosis for cancer in patients with breast lesions scheduled by images as BIRADS 3. The findings of the present study have recollected without enough evidence to justify taking biopsies, suggesting that conservative management would be sufficient for diagnosis approach of lesions BIRADS 3 [es

  18. Role of mini-scleral lens in mucous membrane pemphigoid

    Directory of Open Access Journals (Sweden)

    Mukesh Kumar

    2017-01-01

    Full Text Available This study aims to report the use of mini-scleral contact lens in the management of mucous membrane pemphigoid (MMP with persistent epithelial defects. A 68-year-old male with a history of ocular pain and declining visual acuity was referred to our clinic with a diagnosis of MMP. His corrected distance visual acuity (CDVA was 20/200 in the right eye and 20/100 in the left eye. Despite being on lubricants, topical steroids and intravenous cyclophosphamide, the patient developed persistent corneal epithelial defects in both eyes. He was then given a trial of mini-scleral lenses. Within 4 weeks, corneal epithelial defects healed, and at 6 months, the CDVA had improved to 20/50 in the right eye and 20/40 in the left eye. By improving the corneal surface integrity and visual function, mini-scleral lenses can play a role in the visual rehabilitation of patients with MMP.

  19. A mini-UAV VTOL Platform for Surveying Applications

    Directory of Open Access Journals (Sweden)

    Kuldeep Rawat

    2014-05-01

    Full Text Available In this paper we discuss implementation of a mini-Unmanned Aerial Vehicle (UAV vertical take-off and landing (VTOL platform for surveying activities related to highway construction. Recent advances in sensor and communication technologies have allowed scaling sizes of unmanned aerial platforms, and explore them for tasks that are economical and safe over populated or inhabited areas. In highway construction the capability of mini-UAVs to survey in hostile and/or hardly accessible areas can greatly reduce human risks. The project focused on developing a cost effective, remotely controlled, fuel powered mini-UAV VTOL (helicopter platform with certain payload capacity and configuration and demonstrated its use in surveying and monitoring activities required for highway planning and construction. With an on-board flight recorder global positioning system (GPS device, memory storage card, telemetry, inertial navigation sensors, and a video camera the mini-UAV can record flying coordinates and relay live video images to a remote ground receiver and surveyor. After all necessary integration and flight tests were done the mini-UAV helicopter was tested to operate and relay video from the areas where construction was underway. The mini-UAV can provide a platform for a range of sensors and instruments that directly support the operational requirements of transportation sector.

  20. Social context surrounding HIV diagnosis and construction of masculinity: a qualitative study of stigma experiences of heterosexual HIV positive men in southwest Nigeria.

    Science.gov (United States)

    Okoror, Titilayo Ainegbesua; Falade, Catherine Olufunke; Walker, Ebunlomo Mary; Olorunlana, Adetayo; Anaele, Agaptus

    2016-06-13

    Though research has documented experiences of stigma and its effects on the lives of women living with HIV/AIDS, there is limited research on heterosexual positive HIV men experience of stigma in Nigeria. This study explored how social context surrounding HIV diagnosis impacts stigma experiences of heterosexual HIV positive men and their construction of masculinity in southwest Nigeria. Using purposive sampling, 17 heterosexual HIV positive men were recruited through community based organization to participate in two hours focus group discussions or 45 min in-depth interviews that were audio-recorded. Without using the word stigma, discussions and interviews were guided by four questions that explored participants' experiences of living with HIV/AIDS. Interviews and discussions were conducted in three languages: English, Yoruba and Pidgin English. Thematic data analysis approach was in coding transcribed data, while social constructivist thinking guided data analysis. Participants ranged in age from 30 to 57 years old, and all were receiving antiretroviral therapy. Findings indicated that participants' experiences of stigma might be moderated by the social context surrounding their HIV diagnosis, and whether they have met the socio-cultural construction of masculinity. Participants whose diagnosis were preceded by immediate family members' diagnosis were less likely to report experiencing HIV stigma and more likely to report "not feeling less than a man" and educating others about HIV/AIDS. Contrarily, participants whose diagnosis was preceded by their own sickness were more likely to report isolation, sigma and feeling of being less than a man. All participants reported limiting their sexual intimacy, and those with children reported adjusting how they performed their role as fathers. Social context surrounding HIV diagnosis impact how heterosexual HIV positive men experience HIV related stigma and how they perceive themselves as men, which may influence their

  1. Change in subjective social status following HIV diagnosis and associated effects on mental and physical health among HIV-positive gay men in Australia.

    Science.gov (United States)

    Heywood, Wendy; Lyons, Anthony

    2017-07-01

    This study investigates the impact of HIV diagnosis on subjective social status and if changes are linked to health outcomes. Two measures of subjective social status, socio-economic and standing in the community were examined in 342 Australian HIV-positive gay men in 2014. Participants recalled ratings at diagnosis were compared with current ratings. Self-reported mental (psychological distress, self-esteem, positive mental health and satisfaction with life) and physical health (self-rated health, CD4 count, viral load). Half of the participants reported improvements in subjective socio-economic status (59%) or standing in the community (52%) since diagnosis, yet one quarter reported socio-economic status (25%) or standing in the community had decreased (23%). Increases in either measure of subjective social status were linked to higher self-esteem, positive mental health, satisfaction with life and better self-rated health. Decreases in subjective social status, however, were strongly linked to poorer outcomes on all mental health measures. Decreases in standing in the community were also associated with poorer physical self-rated health. Most participants reported their subjective social status were the same or better since diagnosis. Changes in subjective social status following diagnosis were strongly linked to mental health outcomes. Those who reported a decrease in subjective social status were particularly vulnerable to mental health problems.

  2. Graphic software ''MiniG'' for the Mini-6

    International Nuclear Information System (INIS)

    Zen, J.

    1984-06-01

    MiniG is a set of subprograms, written and aimed at being used in Fortran for graphic applications in nuclear physics (histograms or point clouds). It includes three representation modes of axis scales (linear, semi-log and squared root), five types of vectors and numerous graphic symbols for spectra representation with or without notation (circle, cross, arrow, triangle, spiral, etc.). It offers also the possibilities of the software ''Plot-10'' of Tektronix, and accept all the types of graphic terminals of SATD connected to Mini-6 [fr

  3. In-house PCR with DNA extracted directly from positive slides to confirm or exclude the diagnosis of tuberculosis: focus on biosafety.

    Science.gov (United States)

    de Almeida, Isabela Neves; Aleixo, Agdemir Valéria; Carvalho, Wânia da Silva; de Miranda, Silvana Spindola

    2015-01-01

    The possibility to obtain DNA from smears is a valuable alternative to remedy the lack of samples when they are totally used for bacilloscopy; this technique solves the biosafety problem related to a possible accident with the transportation of flasks containing potentially transmissible clinical samples. Hence, the purpose of this study was to utilize the insertion sequence IS6110 for amplification of DNA from a smear-positive sample for tuberculosis (TB) diagnosis. Among the 52 positive bacilloscopies, sensitivity, specificity, positive predictive value and negative predictive value were 52.3%, 100%, 100% and 89.7%, respectively whereas accuracy was 90.7%. The IS6110-based PCR for TB diagnosis developed in DNA extracted from a positive smear is a fast, simple, specific, and safe method. Copyright © 2014 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.

  4. Positive predictive value and impact of misdiagnosis of a heart failure diagnosis in administrative registers among patients admitted to a University Hospital cardiac care unit

    DEFF Research Database (Denmark)

    Mard, Shan; Nielsen, Finn Erland

    2010-01-01

    OBJECTIVE: To evaluate the positive predictive value (PPV) of a diagnosis of heart failure (HF) in the Danish National Registry of Patients (NRP) among patients admitted to a University Hospital cardiac care unit, and to evaluate the impact of misdiagnosing HF. DESIGN: The NRP was used to identify...

  5. Biological false-positive venereal disease research laboratory test in cerebrospinal fluid in the diagnosis of neurosyphilis - a case-control study.

    Science.gov (United States)

    Zheng, S; Lin, R J; Chan, Y H; Ngan, C C L

    2018-03-01

    There is no clear consensus on the diagnosis of neurosyphilis. The Venereal Disease Research Laboratory (VDRL) test from cerebrospinal fluid (CSF) has traditionally been considered the gold standard for diagnosing neurosyphilis but is widely known to be insensitive. In this study, we compared the clinical and laboratory characteristics of true-positive VDRL-CSF cases with biological false-positive VDRL-CSF cases. We retrospectively identified cases of true and false-positive VDRL-CSF across a 3-year period received by the Immunology and Serology Laboratory, Singapore General Hospital. A biological false-positive VDRL-CSF is defined as a reactive VDRL-CSF with a non-reactive Treponema pallidum particle agglutination (TPPA)-CSF and/or negative Line Immuno Assay (LIA)-CSF IgG. A true-positive VDRL-CSF is a reactive VDRL-CSF with a concordant reactive TPPA-CSF and/or positive LIA-CSF IgG. During the study period, a total of 1254 specimens underwent VDRL-CSF examination. Amongst these, 60 specimens from 53 patients tested positive for VDRL-CSF. Of the 53 patients, 42 (79.2%) were true-positive cases and 11 (20.8%) were false-positive cases. In our setting, a positive non-treponemal serology has 97.6% sensitivity, 100% specificity, 100% positive predictive value and 91.7% negative predictive value for a true-positive VDRL-CSF based on our laboratory definition. HIV seropositivity was an independent predictor of a true-positive VDRL-CSF. Biological false-positive VDRL-CSF is common in a setting where patients are tested without first establishing a serological diagnosis of syphilis. Serological testing should be performed prior to CSF evaluation for neurosyphilis. © 2017 European Academy of Dermatology and Venereology.

  6. The value of high-resolution anoscopy in the diagnosis of anal cancer precursor lesions in hiv-positive patients

    Directory of Open Access Journals (Sweden)

    Felicidad Gimenez

    2011-06-01

    Full Text Available CONTEXT: Anal cancer, although a still rare disease, is being observed in ascending rates among some population segments known to be at risk for the development of the disease. Human papillomavirus (HPV infection, immunodepression and anal intercourse are some factors associated with the development of the malignancy. Its similarities to cervical cancer have led to many studies aiming to establish guidelines for detecting and treating precursor lesions of anal cancer, with the goal of prevention. High-resolution anoscopy is routinely used for the diagnosis of anal cancer precursor lesions in many centers but the medical literature is still deficient concerning the role of this diagnostic modality. OBJECTIVES: To evaluate diagnostic validation and precision measures of high-resolution anoscopy in comparison to histopathological results of anal biopsies performed in HIV-positive patients treated at the Tropical Medicine Foundation of Amazonas, AM, Brazil. To observe any possible association between some risk factors for the development of anal cancer and the presence of anal squamous intraepithelial lesions. METHODS: A hundred and twenty-eight HIV-positive patients were submitted to anal canal cytological sampling for the detection of HPV infection by a PCR based method. High-resolution anoscopy was then performed after topical application of acetic acid 3% in the anal canal for 2 minutes. Eventual acetowhite lesions that were detected were recorded in respect to location, and classified by their tinctorial pattern, distribution aspect, relief, surface and vascular pattern. Biopsies of acetowhite lesions were performed under local anesthesia and the specimens sent to histopathological analysis. The patients were interviewed for the presence of anal cancer risk factors. RESULTS: The prevalences of anal HPV infection and of anal squamous intraepithelial lesions in the studied population were, respectively, 79% and 39.1%. High-resolution anoscopy

  7. Urine-Based Nested PCR for the Diagnosis of Mycobacterium tuberculosis: A Comparative Study Between HIV-Positive and HIV-Negative Patients.

    Science.gov (United States)

    Jamshidi Makiani, Mahin; Davoodian, Parivash; Baghershiroodi, Mahnaz; Nejatizadeh, Abdol Azim; Fakkhar, Farideh; Zangeneh, Mehrangiz; Jahangiri, Nadia

    2016-08-01

    While tuberculosis (TB) can be diagnosed by microscopy and culture, the sensitivity of Ziehl-Neelsen staining is variable and culture results require 4 - 8 weeks to be determined. Polymerase chain reaction (PCR) and its modifications, including nested PCR, might be promising methods for the rapid diagnosis of TB. This study aimed to evaluate the performance of nested PCR on urine samples of human immunodeficiency virus (HIV)-positive and -negative patients with different manifestations of clinical TB. In a prospective study, three early-morning urine samples from 100 patients with pulmonary TB (PTB) or extrapulmonary TB (EPTB) were evaluated using a molecular target with insertion element IS6110, specific to the Mycobacterium tuberculosis genome, and nested PCR was performed. The results were analyzed with SPSS version 22. A total of 100 patients, including 74 (74%) with PTB and 26 (26%) with EPTB, were enrolled. Positive smears were seen in 38 patients (38%). Lymph nodes were the most commonly involved organ in 14 of the 26 (53.8%) EPTB patients (13.5%). Seven (23.1%) of the EPTB patients were HIV-positive. Urine PCR was positive in only 28 patients (28%). Seven HIV-positive patients with PTB showed positive urine PCR results. Moreover, PCR results were positive in only one of the seven HIV-positive subjects with EPTB. Positive PCR results were found in 20 of the 73 HIV-negative patients (27.4%) and in 8 of the 27 HIV-positive patients (29.6%). Therefore, there was no significant difference between the HIV-negative and HIV-positive patients for urine PCR (sensitivity 29.6%, specificity 72.6%; positive and negative predictive values 28% and 72%, respectively; P = 0.138). Nested PCR showed the same sensitivity in HIV-positive and HIV-negative patients. It can be applied as a rapid technique for the diagnosis of TB.

  8. Standardization of the Korean version of Mini-Mental Adjustment to Cancer (K-Mini-MAC) scale: factor structure, reliability and validity.

    Science.gov (United States)

    Kang, Jee In; Chung, Hyun Cheol; Kim, Se Joo; Choi, Hye Jin; Ahn, Joong Bae; Jeung, Hei-Cheul; Namkoong, Kee

    2008-06-01

    Mental adjustment and coping affect the physical outcome and survival as well as quality of life in cancer patients. The Mini-Mental Adjustment to Cancer (Mini-MAC) scale is a new refined, economical and reliable self-rating instrument measuring cognitive and behavioral responses to cancer. The aim of this study was to evaluate the psychometric properties of the Mini-MAC in Korean cancer patients. A total of 208 cancer patients recruited from the Yonsei Cancer Center were assessed with the Mini-MAC and the Hospital Anxiety and Depression Scale (HADS). Principal component analysis with varimax rotation for the Korean version of Mini-MAC (K-Mini-MAC) confirmed four factors. Three had psychometric properties similar to Helpless-Hopeless (HH), Anxious Preoccupation (AP) and Cognitive Avoidance (CA) of the original Mini-MAC. A novel factor, named Positive Attitude, included items of both Fatalism (FA) and Fighting Spirit (FS) from the original version. The five subscales from the original version (AP, HH, FS, FA and CA) and Positive Attitude had acceptable internal reliabilities in our sample (Cronbach's alpha coefficient 0.50-0.86; correlation coefficient of test-retest 0.68-0.88). For the validity, significant interscale correlation was observed in the original five subscales and Positive Attitude. Each subscale including Positive Attitude was also significantly related to Depression and Anxiety of HADS. As a whole, the K-Mini-MAC was a reliable, valid and acceptable tool for Korean cancer patients. These findings can provide information about the cross-cultural validity of Mini-MAC scale's factor structure. Cultural differences were also discussed.

  9. The Galactic Centre Mini-Spiral with CARMA

    Science.gov (United States)

    Kunneriath, D.; Eckart, A.; Vogel, S. N.; Teuben, P.; Muzic, K.; Schodel. R.; Garcia-Marin, M.; Moultaka, J.; Staguhn, J.; Straubmeier, C.; hide

    2012-01-01

    The Galactic centre mini-spiral region is a mixture of gas and dust with temperatures ranging from a few hundred K to 10(exp 4) K. We report results from 1.3 and 3mm radio interferometric observations of this region with CARMA, and present a spectral index map of this region. We find a range of emission mechanisms in the region, including the inverted synchrotron spectrum of Sgr A*, free-free emission from the mini-spiral arms, and a possible dust emission contribution indicated by a positive spectral index.

  10. Use of days of the week in a modified mini-mental state exam (M-MMSE) for detecting geriatric cognitive impairment.

    Science.gov (United States)

    Hamrick, Irene; Hafiz, Razia; Cummings, Doyle M

    2013-01-01

    The purpose of this study was to compare a modified version of the Mini-Mental State Examination (MMSE) with the standard MMSE and the Mini-Cog in patients ≥65 years old, stratified by education and literacy level. This cross-sectional exploratory study enrolled a convenience sample of 219 patients with a complaint of memory loss or a diagnosis of dementia from a geriatric outpatient clinic, nursing home, senior center, and university hospital. The MMSE was administered, and in addition to spelling and serial 7s backward, patients were asked to recite the days of the week backward with the intent to reduce educational bias. Scores on the modified MMSE were compared with scores of the MMSE and the Mini-Cog. Of the 219 patients, 157 were identified with cognitive impairment by the Mini-Cog. Using a cutoff of ≤23, the MMSE identified 118 patients and the modified MMSE identified 91 patients with cognitive impairment, and with a cutoff of ≤27 the MMSE identified 168 and the modified MMSE 149 patients. All cognitively intact subjects correctly recited the days of the week backward. Specificity of the modified MMSE was higher than the MMSE for most groups. The highest sensitivity and specificity (94% and 88%, respectively) as well as positive and negative predictive values (96% and 81%, respectively) were in patients with low levels of education for the modified MMSE using a cut off of ≤27. Using the days of the week in the MMSE among illiterate and semiliterate participants and with education less than high school, and using a cutoff of 27 of 30, correlates better with Mini-Cog for dementia screening, with fewer false positives.

  11. "Mini", "Midi" and the Student.

    Science.gov (United States)

    Edwards, Perry; Broadwell, Bruce

    Mini- and midi-computers have been introduced into the computer science program at Sierra College to afford students more direct contact with computers. The college's administration combined with the Science and Business departments to share the expense and utilization of the program. The National Cash Register Century 100 and the Data General…

  12. Steroid hormone analysis in diagnosis and treatment of DSD: position paper of EU COST Action BM 1303 'DSDnet'

    NARCIS (Netherlands)

    Kulle, A.; N.P. Krone (Nils); P-M. Holterhus (Paul-Martin); G. Schuler (Gerhard); Greaves, R.F.; A. Juul (Anders); Y.B. de Rijke (Yolanda); Hartmann, M.F.; Saba, A.; O. Hiort (Olaf); S.A. Wudy (Stefan)

    2017-01-01

    textabstractDisorders or differences in sex development (DSD) comprise a heterogeneous group of conditions with an atypical sex development. For optimal diagnosis, highly specialised laboratory analyses are required across European countries. Working group 3 of EU COST (European Cooperation in

  13. Diagnosis of pulmonary infection with Toxoplasma gondii in immunocompromised HIV-positive patients by real-time PCR

    DEFF Research Database (Denmark)

    Petersen, E; Edvinsson, B; Lundgren, B

    2006-01-01

    The aim of the study presented here was to evaluate the use of PCR for improving the diagnosis of Toxoplasma gondii infection in immunocompromised hosts. Three hundred thirty-two bronchoalveolar lavage (BAL) fluid samples were analyzed by real-time PCR targeting a 529 bp element of T. gondii. In ...

  14. Risk of Recurrence or Contralateral Breast Cancer More than 5 Years After Diagnosis of Hormone Receptor-Positive Early-Stage Breast Cancer.

    Science.gov (United States)

    Wilson, Sheridan; Speers, Caroline; Tyldesley, Scott; Chia, Stephen; Kennecke, Hagen; Ellard, Susan; Lohrisch, Caroline

    2016-08-01

    Three large studies have shown a survival benefit from 10 years of adjuvant hormone therapy (AHT). We evaluated the risk of an event 5 years after the initial breast cancer (BC) diagnosis and identified the prognostic factors to assist clinicians considering extended AHT. Patients newly referred to the BC Cancer Agency with stage I to III estrogen receptor-positive BC diagnosed from 1989 to 2004 who had undergone AHT were identified by the BC Cancer Agency's Breast Cancer Outcomes Unit. Cases with recurrence, death, or contralateral BC occurring within the first 5 years were excluded. The 10-year event-free survival (EFS) and 95% confidence intervals (CIs) were calculated using the Kaplan-Meier method. This provided estimates of recurrence risk after the fifth year following the diagnosis. The histopathologic and age variables were examined for prognostic value by univariate analysis. Within our cohort, 6615 women were postmenopausal and 1886 were premenopausal at the BC diagnosis. The median follow-up period was 11 years. The 10-year EFS for women aged cancer (any grade) and for stage II (node-negative and node-positive), grade I cancer. Our data have identified BCs associated with a very low recurrence risk 5 to 10 years after diagnosis, providing women with such cancers confidence about a decision to discontinue AHT after 5 years. Copyright © 2015 Elsevier Inc. All rights reserved.

  15. Social context surrounding HIV diagnosis and construction of masculinity: a qualitative study of stigma experiences of heterosexual HIV positive men in southwest Nigeria

    Directory of Open Access Journals (Sweden)

    Titilayo Ainegbesua Okoror

    2016-06-01

    Full Text Available Abstract Background Though research has documented experiences of stigma and its effects on the lives of women living with HIV/AIDS, there is limited research on heterosexual positive HIV men experience of stigma in Nigeria. This study explored how social context surrounding HIV diagnosis impacts stigma experiences of heterosexual HIV positive men and their construction of masculinity in southwest Nigeria. Methods Using purposive sampling, 17 heterosexual HIV positive men were recruited through community based organization to participate in two hours focus group discussions or 45 min in-depth interviews that were audio-recorded. Without using the word stigma, discussions and interviews were guided by four questions that explored participants’ experiences of living with HIV/AIDS. Interviews and discussions were conducted in three languages: English, Yoruba and Pidgin English. Thematic data analysis approach was in coding transcribed data, while social constructivist thinking guided data analysis. Results Participants ranged in age from 30 to 57 years old, and all were receiving antiretroviral therapy. Findings indicated that participants’ experiences of stigma might be moderated by the social context surrounding their HIV diagnosis, and whether they have met the socio-cultural construction of masculinity. Participants whose diagnosis were preceded by immediate family members’ diagnosis were less likely to report experiencing HIV stigma and more likely to report “not feeling less than a man” and educating others about HIV/AIDS. Contrarily, participants whose diagnosis was preceded by their own sickness were more likely to report isolation, sigma and feeling of being less than a man. All participants reported limiting their sexual intimacy, and those with children reported adjusting how they performed their role as fathers. Conclusions Social context surrounding HIV diagnosis impact how heterosexual HIV positive men experience HIV

  16. MiniGRAIL progress report 2004

    International Nuclear Information System (INIS)

    Waard, A de; Benzaim, Y; Frossati, G; Gottardi, L; Mark, H van der; Flokstra, J; Podt, M; Bassan, M; Minenkov, Y; Moleti, A; Rocchi, A; Fafone, V; Pallottino, G V

    2005-01-01

    The MiniGRAIL detector was improved. The sphere was replaced by a slightly larger one, having a diameter of 68 cm (instead of 65 cm), reducing the resonant frequency by about 200 Hz to around 2.9 kHz. The last four masses of the attenuation system were machined to increase their resonant frequency and improve the attenuation around the resonant frequency of the sphere. In the new sphere, six holes were machined on the TIGA positions for easy mounting of the transducers. During the last cryogenic run, two capacitive transducers and a calibrator were mounted on the sphere. The first transducer was coupled to a double-stage SQUID amplifier having a commercial quantum design SQUID as a first stage and a DROS as a second stage. The second transducer was read by a single-stage quantum design SQUID. During the cryogenic run, the sphere was cooled down to 4 K. The two-stage SQUID had a flux noise of about 1.6 μφ 0 Hz -1/2 . The detector was calibrated and the sensitivity curve of MiniGRAIL was determined

  17. Mini-Sniffer on Lakebed

    Science.gov (United States)

    1974-01-01

    The original Mini-Sniffer on Rogers Dry Lake, adjacent to NASA's Flight Research Center, Edwards AFB. This version of the remotely-piloted vehicle had swept-back wings, tip rudders, nose canards, and an air breathing engine. The Mini-Sniffer was a remotely controlled, propeller-driven vehicle developed at the NASA Flight Research Center (which became the Dryden Flight Research Center, Edwards, California, in 1976) as a potential platform to sample the upper atmosphere for pollution. The vehicle, flown from 1975 to 1977, was one of the earliest attempts by NASA to develop an aircraft that could sense turbulence and measure natural and human-produced atmospheric pollutants at altitudes above 80,000 feet with a variable-load propeller that was never flight-tested. Three Mini-Sniffer vehicles were built. The number 1 Mini-Sniffer vehicle had swept wings with a span of 18 feet and canards on the nose. It flew 12 flights with the gas-powered engine at low altitudes of around 2,500 feet. The number 1 vehicle was then modified into version number 2 by removing the canards and wing rudders and adding wing tips and tail booms. Twenty flights were made with this version, up to altitudes of 20,000 feet. The number 3 vehicle had a longer fuselage, was lighter in weight, and was powered by the non-air-breathing hydrazine engine designed by NASA's Johnson Space Center in Houston, Texas. This version was designed to fly a 25-pound payload to an altitude of 70,000 feet for one hour or to climb to 90,000 feet and glide back. The number 3 Mini-Sniffer made one flight to 20,000 feet and was not flown again because of a hydrazine leak problem. All three versions used a pusher propeller to free the nose area for an atmospheric-sampling payload. At various times the Mini-Sniffer has been considered for exploration in the carbon dioxide atmosphere of the planet Mars, where the gravity (38 percent of that on Earth) would reduce the horsepower needed for flight.

  18. Validity and Reliability of the Arabic Version of the Positive and Negative Syndrome Scale.

    Science.gov (United States)

    Yehya, Arij; Ghuloum, Suhaila; Mahfoud, Ziyad; Opler, Mark; Khan, Anzalee; Hammoudeh, Samer; Abdulhakam, Abdulmoneim; Al-Mujalli, Azza; Hani, Yahya; Elsherbiny, Reem; Al-Amin, Hassen

    The Positive and Negative Syndrome Scale (PANSS) is widely used for patients with schizophrenia. This scale is reliable and valid. The PANSS was translated and validated in several languages. The aim of this study was to translate and validate the PANSS in the Arab population. The PANSS was translated into formal Arabic language using the back-translation method. 101 Arab patients with schizophrenia and 98 Arabs with no diagnosis of any mental disorder were recruited. The Arabic version of the Mini International Neuropsychiatric Interview (MINI-6) was used as a diagnostic tool to confirm the diagnosis of schizophrenia or rule out any diagnosis for the healthy control group. Reliability of the scale was assessed by calculating internal consistency, interrater reliability and test-retest reliability. Construct validity was assessed using the Arabic version of the MINI-6. PANSS total scores were correlated with the Clinical Global Impression-Severity scale. Our findings showed that the internal consistency was good (0.92). Scores on the PANSS of the patients were much higher than those of the healthy controls. The PANSS showed good interrater reliability and test-retest reliability (0.92 and 0.75, respectively). In comparison with the MINI-6, the PANSS showed good sensitivity and specificity, which implies good construct validity of this version. In conclusion, the Arabic version of the PANSS is a reliable and valid instrument for the assessment of patients with schizophrenia in the Arab population. © 2016 S. Karger AG, Basel.

  19. Summer Mini Atomiade June 2016

    CERN Multimedia

    Staff Association

    2016-01-01

    The Mini Atomiade are coming to CERN! Members of Clubs supported by the CERN Staff Association and in conjunction with ASCERI (Association of the Sports Communities of the European Research Institutes) will be organising the summer games at the beginning of June. ASCERI aims to contribute to a united Europe through regular sports meetings, bringing together members of public Research Institutes at European level. The Association's members come from over 40 Research Institutes spanning 16 countries. Numerous sports and leisure activities are represented at regular events and each tournament is organised by a different research institute. Clubs in conjunction with the CERN Staff Association have sent teams to previous winter and summer games and now, the CERN Club’s Coordination Committee (CCC) has now taken on the challenge of organising a Mini Atomiade from Friday June 3rd to Monday June 6th 2016 in Divonne-les-Bains. The games are made up of four different tournaments/competitions: Small Fi...

  20. Mini-guide til DGNB

    DEFF Research Database (Denmark)

    Larsen, Tine Steen

    Guiden giver et kort indblik i formålet med de enkelte kriterier i en DGNB- bæredygtighedsvurdering, samt i hvordan der kan måles på kriterierne. Mini-guiden tager afsæt i systemet for certificering af Nybyggede kontor-og erhvervsbyggerier, som er det første og grundlæggende system i DGNB, som al...

  1. Development of mini VSAT system

    Science.gov (United States)

    Lu, Shyue-Ching; Chiu, Wu-Jhy; Lin, Hen-Dao; Shih, Mu-Piao

    1992-03-01

    This paper presents the mini VSAT (very small aperture terminal) system, which is a low cost networking system providing economical alternatives to the business world's datacom needs. The system is designed to achieve the highest possible performance/price ratio for private VSAT networks that range from a few tens of remote terminals to large networks of several thousands remote terminals. The paper describes the system architecture, major features, hardware and software structure, access protocol and performance of the developed system.

  2. Diagnosis of pulmonary infection with Toxoplasma gondii in immunocompromised HIV-positive patients by real-time PCR

    DEFF Research Database (Denmark)

    Petersen, E.; Edvinsson, B.; Lundgren, Bettina

    2006-01-01

    . In positive samples, the genotype of the parasite was determined by sequence analysis of the GRA6 gene. Positive results were achieved for 2% (7/332) of the samples tested. Genotyping was possible in two samples and revealed GRA6 type II T. gondii. PCR for detecting T. gondii in BAL samples should...... be performed in all immunosuppressed HIV-positive patients with symptoms of a systemic infection of unknown etiology. Trimethoprim-sulfamethoxazole prophylaxis does not exclude concomitant infection with T. gondii....

  3. Late diagnosis of positive HIV serology in pregnancy incidentally discovered by the widespread appearance of Kaposi's sarcoma.

    Science.gov (United States)

    Mian, D B; Itoua, C; Angoi, V; Gbary, E; Nguessan, K L P; Iloki, H; Boni, S

    2015-01-01

    The authors report a case of Kaposi's sarcoma (KS) found in a pregnant woman. On discovery, the condition had spread throughout her body as is characteristic in some cases of individuals with HIV-positive serology. She was unaware of her HIV positive status. Her HIV infection had been diagnosed at the same time as KS at her last prenatal consultation. The newborn was delivered by an uncomplicated cesarean section. Appropriate treatment and multidisciplinary management after childbirth resulted in complete remission.

  4. Disclosure, stigma of HIV positive child and access to early infant diagnosis in the rural communities of OR Tambo District, South Africa: a qualitative exploration of maternal perspective.

    Science.gov (United States)

    Adeniyi, Vincent Oladele; Thomson, Elza; Ter Goon, Daniel; Ajayi, Idowu Anthony

    2015-08-26

    Despite the overwhelming evidence confirming the morbidity and mortality benefits of early initiation of highly active anti-retroviral therapy (HAART) in HIV-infected infants, some children are still disadvantaged from gaining access to care. The understanding of the maternal perspective on early infant HIV diagnosis and prompt initiation of HAART has not been adequately explored, especially in the rural communities of South Africa. This study explores the perspectives of mothers of HIV-exposed infants with regard to early infant diagnosis (EID) through a lens of social and structural barriers to accessing primary healthcare in OR Tambo district, Eastern Cape Province, South Africa. In this qualitative study, we conducted semi-structured interviews at two primary healthcare centres in the King Sabata Dalindyebo Municipality of the OR Tambo district, South Africa. Twenty-four purposive sample of mothers of HIV-exposed infants took part in the study. Interviews were tape-recorded, transcribed and field notes were obtained. The findings were triangulated with two focus group discussions in order to enrich and validate the qualitative data. Thematic content analysis was employed to analyse the data. The participants have fairly good knowledge of mother-to-child transmission of HIV and the risks during pregnancy, delivery and breastfeeding. The majority of participants were confident of the protection offered by anti-retroviral drugs provided during pregnancy, however, lack knowledge of optimal time for early infant diagnosis of HIV. Reasons for not accessing EID included fear of finding out that their child is HIV positive, feelings of guilt and/or shame and embarrassment with respect to raising an HIV infected infant. Personal experiences of HIV diagnosis and HAART were associated with participants' attitudes and beliefs toward care-seeking behaviours. Stigma resulting from their own disclosure to others reduced their likelihood of recommending EID to other members of

  5. Small Intestinal Bacterial Overgrowth May Increase the Likelihood of Lactose and Sorbitol but not Fructose Intolerance False Positive Diagnosis.

    Science.gov (United States)

    Perets, Tsachi Tsadok; Hamouda, Dalal; Layfer, Olga; Ashorov, Olga; Boltin, Doron; Levy, Sigal; Niv, Yaron; Dickman, Ram

    2017-08-01

    Small intestinal bacterial overgrowth (SIBO) is defined as a bacterial count of more than 10 5 colony-forming units per milliliter in duodenal aspirate. It shares many symptoms with carbohydrate intolerance, which makes the clinical distinction of the disorders difficult. The aim of the study was to examine the relationship between a positive carbohydrate breath test and the presence of SIBO suggested by a positive lactulose hydrogen breath test. The electronic database of the gastroenterology laboratory of a tertiary medical center was searched for all patients clinically tested for SIBO in 2012-2013 for whom previous results for lactose, fructose, and/or sorbitol breath test were available. The correlation between positive findings for carbohydrate intolerance and for SIBO was statistically analyzed. The study group included 349 patients, 231 female and 118 male, of mean age 53±19 years. All had symptoms of abdominal bloating and gas. There was a statistically significant difference in rates of a positive breath test for lactose and sorbitol at ≤90 minutes between patients who were positive and negative for SIBO [χ 2 (1)=12.8, p <0.01 and χ 2 (1)=9.5, p <0.01 respectively]. Findings for fructose were not significant. There was no effect of age or gender. SIBO may represent an important reversible cause of carbohydrate intolerance. It may be especially prudent to exclude SIBO patients with an early peak (≤90 minutes) in H 2 excretion. © 2017 by the Association of Clinical Scientists, Inc.

  6. Office-based 3D-CT examined in the sitting position is useful for diagnosis of patulous eustachian tube (pET)

    International Nuclear Information System (INIS)

    Kikuchi, Toshiaki; Oshima, Takeshi; Kobayashi, Toshimitsu

    2010-01-01

    The pET symptoms are tended to be masked in the recumbent position. CT for pET should be examined in the sitting position. CT was performed under the resting and Valsalva's condition. Completely open ET was observed in 79.2% of the pET group (n=111), but in none of the control group (n=30). The average ET-gram showed an occlusive zone (OZ) in medial to the isthmus under both conditions in only control group. Trans-tympanic silicone plug insertion was thought to be reasonable technique because of obliteration approach to isthmus. Office-based CT examined in the sitting position is useful for diagnosis and evaluation of pET. (author)

  7. Model Documentation for the MiniCAM

    Energy Technology Data Exchange (ETDEWEB)

    Brenkert, Antoinette L.; Smith, Steven J.; Kim, Son H.; Pitcher, Hugh M.

    2003-07-17

    The MiniCAM, short for the Mini-Climate Assessment Model, is an integrated assessment model of moderate complexity focused on energy and agriculture sectors. The model produces emissions of greenhouse gases (carbon dioxide, methane and nitrous oxide) and other radiatively important substances such as sulfur dioxide. Through incorporation of the simple climate model MAGICC, the consequences of these emissions for climate change and sea-level rise can be examined. The MiniCAM is designed to be fast and flexible.

  8. The diagnosis of nonclassic congenital adrenal hyperplasia due to 21-hydroxylase deficiency, based on serum basal or post-ACTH stimulation 17-hydroxyprogesterone, can lead to false-positive diagnosis.

    Science.gov (United States)

    Ambroziak, Urszula; Kępczyńska-Nyk, Anna; Kuryłowicz, Alina; Małunowicz, Ewa Maria; Wójcicka, Anna; Miśkiewicz, Piotr; Macech, Magdalena

    2016-01-01

    As nonclassic congenital adrenal hyperplasia (NCCAH) needs to be taken into account in women with hyperandrogenism, we aimed to assess whether the recommended level of poststimulated 17OHP ≥30 nmol/l confirms NCCAH. Forty, consecutive women with biochemical and/or clinical hyperandrogenism (aged 25·4, 18-38) suspected of having NCCAH were recruited to the study. In patients with 17OHP level between 5·1 and 29·9 nmol/l an ACTH stimulation test was performed. In patients with basal or poststimulated 17OHP ≥30 nmol/l, twenty-four-hour urinary steroid profile (USP) analysis was performed and CYP21A2 mutation was assessed. In selected patients with poststimulated 17OHP basal or poststimulated 17OHP ≥30 nmol/l (group A) and with poststimulated 17OHP basal or poststimulated 17OHP ≥30 nmol/l was found in 21, but NCCAH was confirmed by USP followed by genetic testing only in 5 (24%). Four patients were diagnosed as heterozygotes, and in twelve, no CYP21A2 mutation was detected. The diagnosis of NCCAH based only on serum 17OHP measurements (basal or poststimulated) may lead to false-positive diagnosis when performed by immunoassay with a cut-off value of ≥30 nmol/l. The definitive diagnosis can be established based on USP and/or genetic testing. © 2015 John Wiley & Sons Ltd.

  9. Movimentação de molares inferiores ancorados em mini-parafusos Mandibular molar uprighting, using mini-screw as anchorage

    Directory of Open Access Journals (Sweden)

    Rosana Canteras Di Matteo

    2005-08-01

    Full Text Available Freqüentemente a movimentação ortodôntica exige recursos adicionais de ancoragem. Os mini-parafusos têm-se apresentado como uma possível solução. O propósito deste trabalho foi estabelecer um método para a verticalização de molares inferiores inclinados para mesial, utilizando ancoragem em mini-parafusos colocados na região de linha oblíqüa externa da mandíbula. Foram selecionados três pacientes entre 40 a 48 anos (dois do gênero feminino, um do gênero masculino, com molares inferiores inclinados para mesial e distalmente posicionados às áreas edêntulas. Os pacientes foram tratados ortodonticamente durante um período de 6 a 12 meses, com técnica ortodôntica MD3. Mini-parafusos de titânio foram colocados bilateralmente com anestesia local. Uma incisão sobre a linha oblíqüa externa da mandíbula, medindo aproximadamente 1 cm foi realizada em cada lado, distalmente aos molares inclinados. Após descolamento muco-periosteal, mini-parafusos foram implantados e foram realizadas suturas deixando suas cabeças exteriorizadas. Uma semana após a remoção das suturas, cargas ortodônticas (entre 150 a 200 gramas/força foram aplicadas através de forças elásticas. Verificamos que alguma inflamação foi observada ao redor dos mini-parafusos, mas foi controlada com procedimentos de higienização. O procedimento cirúrgico é simples, podendo ser realizado pelo ortodontista; as formas dimensionais dos mini-parafusos são adequadas e estes são de fácil remoção após uso. Concluímos que o uso de mini-parafusos representa uma alternativa efetiva de ancoragem ortodôntica na verticalização de molares inferiores.Tooth movement frequently requires additional anchorage resources. Mini-screws have been used as a possible solution to this matter. The purpose of this study was to establish a method of mandibular molar uprighting, using mini-screw as anchorage, positioned on the mandibular external oblique line, behind and

  10. iPad mini for dummies

    CERN Document Server

    Baig, Edward C

    2014-01-01

    Find out why the iPad mini has never been bigger This new edition of iPad mini For Dummies covers all the latest tips and tricks for getting an even bigger bang out of your iPad mini. Presented in full-color and written in the straightforward but fun language that has defined the For Dummies brand for more than twenty years, this friendly guide walks you through the multitouch interface, going online, getting connected, packing your iPad mini with apps, games, e-books, photos, music, and movies, synchronizing your data, texting with iMessage, working with Siri, importing pictures and launching

  11. Teach yourself visually Mac Mini

    CERN Document Server

    Hart-Davis, Guy

    2012-01-01

    The perfect how-to guide for visual learners Apple?s Mac Mini packs a powerful punch is in a small package, including both HDMI and Thunderbolt ports plus the acclaimed OS X. But if you want to get the very most from all this power and versatility, be sure to get this practical visual guide. With full-color, step-by-step instructions as well as screenshots and illustrations on every page, it clearly shows you how to accomplish tasks rather than burying you in pages of text. Discover helpful visuals and how-tos on the OS, hardware specs, Launchpad, the App Store, multimedia capabilities (such

  12. Diagnosis, management and treatment of glucometabolic disorders emerging after kidney transplantation: a position statement from the Nordic Transplantation Societies.

    Science.gov (United States)

    Hornum, Mads; Lindahl, Jørn P; von Zur-Mühlen, Bengt; Jenssen, Trond; Feldt-Rasmussen, Bo

    2013-11-01

    After successful solid organ transplantation, new-onset diabetes (NODAT) is reported to develop in about 15-40% of the patients. The variation in incidence may partly depend on differences in the populations that have been studied and partly depend on the different definitions of NODAT that have been used. The diagnosis was often based on 'the use of insulin postoperatively', 'oral agents used', random glucose monitoring and a fasting glucose value between 7 and 13 mmol/l (126-234 mg/dl). Only few have used a 2-h glucose tolerance test performed before transplantation. There is a huge variation in the literature regarding risk factors for developing NODAT. They can be divided into factors related to glucose metabolism or to patient demographics and the latter into modifiable and nonmodifiable. Screening for risk factors should start early and be re-evaluated while being on the waitlist. Patients on the waiting list for renal transplantation and transplanted patients share many characteristics in having hyperglycaemia, disturbed insulin secretion and increased insulin resistance. We present guidelines for early risk factor assessment and a screening/treatment strategy for disturbed glucose metabolism, both before and after transplantation. The aim was to avoid the increased cardiovascular disease and mortality rates associated with NODAT. © 2013 Steunstichting ESOT. Published by John Wiley & Sons Ltd.

  13. Position statement executive summary: guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus.

    Science.gov (United States)

    Sacks, David B; Arnold, Mark; Bakris, George L; Bruns, David E; Horvath, Andrea Rita; Kirkman, M Sue; Lernmark, Ake; Metzger, Boyd E; Nathan, David M

    2011-06-01

    Multiple laboratory tests are used in the diagnosis and management of patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these assays varies substantially. An expert committee compiled evidence-based recommendations for the use of laboratory analysis in patients with diabetes. A new system was developed to grade the overall quality of the evidence and the strength of the recommendations. A draft of the guidelines was posted on the Internet, and the document was modified in response to comments. The guidelines were reviewed by the joint Evidence-Based Laboratory Medicine Committee of the AACC and the National Academy of Clinical Biochemistry and were accepted after revisions by the Professional Practice Committee and subsequent approval by the Executive Committee of the American Diabetes Association. In addition to the long-standing criteria based on measurement of venous plasma glucose, diabetes can be diagnosed by demonstrating increased hemoglobin A(1c) (HbA(1c)) concentrations in the blood. Monitoring of glycemic control is performed by the patients measuring their own plasma or blood glucose with meters and by laboratory analysis of HbA(1c). The potential roles of noninvasive glucose monitoring, genetic testing, and measurement of autoantibodies, urine albumin, insulin, proinsulin, C-peptide, and other analytes are addressed. The guidelines provide specific recommendations based on published data or derived from expert consensus. Several analytes are found to have minimal clinical value at the present time, and measurement of them is not recommended.

  14. [Frequency of intestinal microsporidian infections in HIV-positive patients, as diagnosis by quick hot Gram chromotrope staining and PCR].

    Science.gov (United States)

    Botero, Jorge H; Montoya, Martha Nelly; Vanegas, Adriana Lucía; Díaz, Abel; Navarro-i-Martínez, Luis; Bornay, Fernando Jorge; Izquierdo, Fernando; del Aguila, Carmen; Agudelo, Sonia del Pilar

    2004-12-01

    Microsporidia are intracellular obligate parasites, today mainly associated with diarrhea in AIDS patients. Microsporidia prevalence ranges from 8% to 52% in different countries, as evaluated by several diagnostic methods, such as the stain test and PCR. In Medellín, Colombia, its frequency is unknown, and hence, a study was undertaken to determine the frequency of intestinal microsporidiosis in HIV patients, by means of the quick-hot Gram chromotrope test and the PCR. A prospective and descriptive study of an intentional population of all HIV-positive patients was sent to the Grupo Interdisciplinario para el Estudio de las Parasitosis Intestinales laboratory by institutions treating the HIV-positive patients of Medellín between August 2001 and September 2002. The clinical-epidemiological survey included a serial stool test with direct concentration and special stains for coccidiae and intestinal microsporidia. In addition, counts of lymphocytes TCD4+ and viral load were requested. One hundred and three patients with ages ranging from 2-74 years were evaluated. Seventy percent presented with diarrhea--mostly in men (83.5%). The overall frequency of intestinal microsporidiosis was 3.9% and that of other intestinal parasitic infections was 39.8%. Three of the four patients positive for microsporida were infected with Enterocytozoon bieneusi and one with Encephalitozoon intestinalis. The microsporidiosis frequency was relatively low with 3 of the 4 cases associated with protracted diarrhea, counts of LTCD4+ below 100 cel/microl and viral loads up to 100,000 copies.

  15. Mini-Open Latarjet Procedure for Recurrent Anterior Shoulder Instability

    Directory of Open Access Journals (Sweden)

    Numa Mercier

    2011-01-01

    Full Text Available Anterior shoulder instability is a common problem. The Latarjet procedure has been advocated as an option for the treatment of anteroinferior shoulder instability. The purpose of this paper is to explain our surgical procedure titled “Mini-open Latarjet Procedure.” We detailed patient positioning, skin incision, subscapularis approach, and coracoid fixation. Then, we reviewed the literature to evaluate the clinical outcomes of this procedure.

  16. False positive of the scintigraphy with octreoscan: a diagnosis of elimination; Faux positif de la scintigraphie a l'octreoscan: un diagnostic d'elimination

    Energy Technology Data Exchange (ETDEWEB)

    Charrier, N.; Brenot-Rossi, I.; Chuto, G.; Giovannini, M.; Delpero, J.R. [Institut Paoli-Calmettes, Marseille, (France)

    2009-05-15

    The imaging of receptors with somatostatin analogs by the pentetreotide-indium 111 (octreoscan) allows the detection of endocrine tumors essentially according to the density of S.S.T.2 receptors at the tumor level. The sensitivity of octreoscan for the detection of intestine endocrine tumors is included between 80 and 100% in the different studies. The clinical case presented here enlightens a case of false positive.We concluded to a physiological elimination of pentetreotide-indium 111 with intra pancreatic biliary stasis (perhaps a dysfunction of sphincter of ampulla of bile duct) and to the lack of tumor centre. It is here a diagnosis of elimination, supported by the different results of examination. all normal. This case of false positive induced expensive and traumatic explorations for the patient. (N.C.)

  17. Technology advanced mini-eyesafe rangefinder (TAMER)

    Science.gov (United States)

    Abousleman, Glen P.; Smeed, Bill

    1998-08-01

    The Technology Advanced Mini-Eyesafe Rangefinder (TAMER) module is a portable, lightweight (7 lbs), hand-held, target determination system. This rapid prototype program involved the integration of a Motorola 68360 microprocessor, electronic compass, laser range finder, GPS, 4 PCMCIA expansion slots, 0.7-inch micro display, digital camera, floating point unit, and various communications interfaces. The CPU computes an absolute target position based on laser range to target, C/VAM azimuth and inclination inputs, and absolute GPS position. This target position is automatically formatted into a standard military surveillance report and stored in local non- volatile memory. The operator can attach to a SINCGARS radio or to any RS232 compatible system (e.g., cellular telephone). To facilitate the above functionality, the TAMER system utilizes various power saving strategies including software- geared power reduction, power supply configuration, external device integration, and incorporation of low-power ICs. Additionally, TAMER utilizes state-of-the-art digital image compression technology. This custom image coder is based on wavelet decomposition and trellis-coded quantization (TCQ). The algorithm enables TAMER to transmit useful imagery over its severely disadvantaged wireless link.

  18. Understanding discontinuation of oral adjuvant endocrine therapy by women with hormone receptor-positive invasive breast cancer nearly 4 years from diagnosis.

    Science.gov (United States)

    Bell, Robin J; Fradkin, Pamela; Schwarz, Max; Davis, Susan R

    2013-01-01

    The aim of this study was to investigate the extent of discontinuation of oral adjuvant endocrine therapy (OAET) in women nearly 4 years from the diagnosis of their first episode of invasive breast cancer and the reasons for such discontinuation. We used a large, prospective cohort study of women who had been diagnosed with their first episode of invasive breast cancer between 2004 and 2006, recruited through a state-based cancer registry. All participants completed an enrollment questionnaire (EQ) within 12 months of diagnosis and annual follow-up questionnaires (FQs) thereafter. The data in this report were obtained from the EQ and the first three FQs. A total of 1,370 women with hormone receptor-positive disease completed the EQ. At the completion of the third FQ nearly 4 years from diagnosis, 1,193 women remained in the study. Use of OAET peaked by 2 years postdiagnosis. At nearly 4 years from diagnosis, 18% of the 1,193 women remaining in the study were not taking OAET. Of these women, just more than half had ceased therapy mainly owing to a range of adverse effects, predominantly estrogen deficiency symptoms, but the remainder (8% of women remaining in the study) had never used OAET. Our study confirms that early discontinuation of OAET due to estrogen deficiency symptoms remains an important issue despite calls for strategies to address this problem. The number of women potentially suitable for OAET but not receiving it was almost as great as the number of those who have discontinued therapy.

  19. Sensitivity, specificity and predictive probability values of serum agglutination test titres for the diagnosis of Salmonella Dublin culture-positive bovine abortion and stillbirth.

    Science.gov (United States)

    Sánchez-Miguel, C; Crilly, J; Grant, J; Mee, J F

    2018-06-01

    The objective of this study was to determine the diagnostic value of maternal serology for the diagnosis of Salmonella Dublin bovine abortion and stillbirth. A retrospective, unmatched, case-control study was carried out using twenty year's data (1989-2009) from bovine foetal submissions to an Irish government veterinary laboratory. Cases (n = 214) were defined as submissions with a S. Dublin culture-positive foetus from a S. Dublin unvaccinated dam where results of maternal S. Dublin serology were available. Controls (n = 415) were defined as submissions where an alternative diagnosis other than S. Dublin was made in a foetus from an S. Dublin unvaccinated dam where the results of maternal S. Dublin serology were available. A logistic regression model was fitted to the data: the dichotomous dependent variable was the S. Dublin foetal culture result, and the independent variables were the maternal serum agglutination test (SAT) titre results. Salmonella serology correctly classified 87% of S. Dublin culture-positive foetuses at a predicted probability threshold of 0.44 (cut-off at which sensitivity and specificity are at a maximum, J = 0.67). The sensitivity of the SAT at the same threshold was 73.8% (95% CI: 67.4%-79.5%), and the specificity was 93.2% (95% CI: 90.3%-95.4%). The positive and negative predictive values were 84.9% (95% CI: 79.3%-88.6%) and 87.3% (95% CI: 83.5%-91.3%), respectively. This study illustrates that the use of predicted probability values, rather than the traditional arbitrary breakpoints of negative, inconclusive and positive, increases the diagnostic value of the maternal SAT. Veterinary laboratory diagnosticians and veterinary practitioners can recover from the test results, information previously categorized, particularly from those results declared to be inconclusive. © 2017 Blackwell Verlag GmbH.

  20. MiniBooNE Oscillation Results

    International Nuclear Information System (INIS)

    Djurcic, Zelimir

    2009-01-01

    These proceedings summarize the MiniBooNE ν μ → ν e results, describe the first (bar ν) μ → (bar ν) e result, and current analysis effort with the NuMI neutrinos detected in the miniBooNE detector

  1. Design guidelines for mini-roundabouts

    CSIR Research Space (South Africa)

    Emslie, I

    1997-03-01

    Full Text Available Guidelines for Traffic Calming. Concepts and principles relating to the use of mini-roundabouts as a form of intersection control and in the traffic calming context are discussed. Warrants for the implementation of mini-roundabouts and design standards...

  2. Mini lathe machine converted to CNC

    Directory of Open Access Journals (Sweden)

    Alexandru Morar

    2012-06-01

    Full Text Available This paper presents the adaptation of a mechanical mini-lathing machine to a computerized numerical control (CNC lathing machine. This machine is composed of a ASIST mini-lathe and a two-degrees-of-freedom XZ stage designed specifically for this application. The whole system is controlled from a PC using adequate CNC control software.

  3. Direct typing of Canine parvovirus (CPV) from infected dog faeces by rapid mini sequencing technique.

    Science.gov (United States)

    V, Pavana Jyothi; S, Akila; Selvan, Malini K; Naidu, Hariprasad; Raghunathan, Shwethaa; Kota, Sathish; Sundaram, R C Raja; Rana, Samir Kumar; Raj, G Dhinakar; Srinivasan, V A; Mohana Subramanian, B

    2016-12-01

    Canine parvovirus (CPV) is a non-enveloped single stranded DNA virus with an icosahedral capsid. Mini-sequencing based CPV typing was developed earlier to detect and differentiate all the CPV types and FPV in a single reaction. This technique was further evaluated in the present study by performing the mini-sequencing directly from fecal samples which avoided tedious virus isolation steps by cell culture system. Fecal swab samples were collected from 84 dogs with enteritis symptoms, suggestive of parvoviral infection from different locations across India. Seventy six of these samples were positive by PCR; the subsequent mini-sequencing reaction typed 74 of them as type 2a virus, and 2 samples as type 2b. Additionally, 25 of the positive samples were typed by cycle sequencing of PCR products. Direct CPV typing from fecal samples using mini-sequencing showed 100% correlation with CPV typing by cycle sequencing. Moreover, CPV typing was achieved by mini-sequencing even with faintly positive PCR amplicons which was not possible by cycle sequencing. Therefore, the mini-sequencing technique is recommended for regular epidemiological follow up of CPV types, since the technique is rapid, highly sensitive and high capacity method for CPV typing. Copyright © 2016. Published by Elsevier B.V.

  4. Measuring mental health in the clinical setting: what is important to service users? The Mini-Service user Recovery Evaluation scale (Mini-SeRvE).

    Science.gov (United States)

    Barber, Joanna M; Parsons, Helen; Wilson, Carol A; Cook, Christopher C H

    2017-12-01

    Since 2001, a policy of positive mental health recovery has been promoted in the UK, with service user involvement. This has not been easy to implement in the clinical setting. To develop and validate a brief self-report, service user-designed, outcome measure (Mini-SeRvE), for clinical use, including spiritual and religious issues. From the previously developed Service user Recovery Evaluation scale (SeRvE), 15 questions were selected for Mini-SeRvE which was self-completed by 207 people; 100 service users and, for comparison, 107 staff. Results were analysed using SPSS software (SPSS Inc., Chicago, IL). Mini-SeRvE is reliable, Cronbach's alpha 0.852. Correlation with another recovery scale, Mental Health Recovery Measure, was high, r = 0.819. Three reliable subscales emerged; existential well-being (EWB), mental ill-being (MIB) and religious well-being (RWB). Scores of the EWB and MIB subscales were higher for staff, consistent with higher mental well-being. Religious well-being scores were higher in service users, who also rated religion as more important to them. Mini-SeRvE is a valid measure of service user recovery. The importance of religion/spiritual belief for our users is highlighted, this being reflected in the subject matter of Mini-SeRvE. Mini-SeRvE assessments could show individual priorities, evaluate therapy and aid clinical decision-making.

  5. Initial validation of the Mini-Mental Adjustment to Cancer (Mini-MAC) scale: study of Portuguese end-of-life cancer patients.

    Science.gov (United States)

    Pereira, Filomena Moreira Pinto; Santos, Célia Samarina Vilaça de Brito

    2014-10-01

    The Mini-Mental Adjustment to Cancer Scale (Mini-MAC) is a 29-item instrument designed to evaluate the responses developed by cancer patients during their mental adjustment to diagnosis and treatment. This study aims to validate the Mini-Mental Adjustment to Cancer Scale (Mini-MAC) translated and adapted to the Portuguese language and culture, in end-of-life cancer patients receiving palliative care. The instrument was administered to 346 Portuguese end-of-life cancer patients, receiving care through outpatient visits or admitted into palliative care units, without cognitive symptoms and with symptoms under control. A cross-sectional validation study using orthogonal rotation through the varimax method followed by convergent and discriminant validity. The analysis of the main components confirms the existence of five factors, demonstrating the validity of the construct, with good internal consistency in the subscales and Cronbach's alpha values between 0.78 and 0.93. Good test-retest reliability was also found, and r values for subscales ranged from 0.62 to 0.99. The instrument proved to be a reliable, valid and sensitive measure in the study of mental adjustment of Portuguese end-of-life patients with cancer receiving palliative care. Nurses can use the Mini-MAC Scale in research and clinical practice in order to evaluate the mental adjustment of Portuguese end-of-life cancer patients receiving palliative care. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. Positioning irrigation of contrast cystography for diagnosis of occult vesicoureteric reflux: association with technetium-99m dimercaptosuccinic acid scans.

    Science.gov (United States)

    Berger, Christoph; Becker, Tanja; Koen, Mark; Zeino, Mazen; Fitz, Friedrich; Beheshti, Mohsen; Wolf-Kohlmeier, Iris; Haim, Silke; Riccabona, Marcus

    2013-12-01

    Positioning irrigation of contrast (PIC) cystography identifies occult or PIC vesicoureteral reflux (PIC-VUR) in children with recurrent febrile urinary tract infections (UTI) but no vesicoureteric reflux (VUR) on standard voiding cystourethrogram (VCUG). We sought to identify the relationship between PIC-VUR and renal scarring in technetium-99m dimercaptosuccinic acid (DMSA) scans. We retrospectively analysed PIC cystograms and DMSA scans for 154 kidneys in 81 children (65 girls; 16 boys; median age, 4.7 years; range, 0.9-15.2). Renal scarring was graded on a scale of 0-3. DMSA scans were pathologic in 66 patients (81%). Children had experienced mean 3.8 febrile UTI (range 1-25). Forty-seven (58%) children had a history of reflux, including 15 (19%) with previous anti-reflux operations. Indications for PIC cystography were recurrence of febrile UTI after either bilateral negative VCUG (66 children) or unilateral VUR (15 children) with contralateral/bilateral scarring or reflux that had changed sides in subsequent VCUGs. PIC-VUR was bilateral in 63, unilateral in 12, and absent in 6 children. Statistically significant associations between PIC-VUR grade and severity of renal scarring were identified in inter-individual (n = 77, p = 0.017) and intra-individual (refluxing vs. nonrefluxing kidney; n = 12, p = 0.008) analyses. After excluding patients with history of VUR, statistical significance was maintained in inter-individual analysis (n = 49; p = 0.018). The data suggest an association between PIC-VUR and severity of renal scarring, and legitimise the use of PIC cystography in children with renal scarring due to recurrent febrile UTI but negative findings on VCUG. Copyright © 2012 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.

  7. The Mini-Social Phobia Inventory: psychometric properties in an adolescent general population sample.

    Science.gov (United States)

    Ranta, Klaus; Kaltiala-Heino, Riittakerttu; Rantanen, Päivi; Marttunen, Mauri

    2012-07-01

    Onset of social phobia (SP) typically occurs in adolescence. Short screening instruments for its assessment are needed for use in primary health and school settings. The 3-item Mini-Social Phobia Inventory (SPIN) has demonstrated effectiveness in screening for generalized SP (GSP) in adults. This study examined the psychometrics of the Mini-SPIN in an adolescent general population sample. Three hundred fifty adolescents aged 12 to 17 years were clinically interviewed using the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version for identification of SP and other Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Axis I disorders, blind to their Mini-SPIN status. Associations between SP; subclinical SP; other anxiety, depressive, and disruptive disorders; and Mini-SPIN scores were examined, and diagnostic efficiency statistics were calculated. The association between Mini-SPIN scores and the generalized subtype of SP was also examined. As in adults, the Mini-SPIN items differentiated subjects with SP from those without. A score of 6 points or greater was found optimal in predicting SP with a sensitivity of 86%, specificity of 84%, and positive and negative predictive values of 26% and 99%. The Mini-SPIN also possessed discriminative validity, as scores were higher for adolescents with SP than they were for those with depressive, disruptive, and other anxiety disorders. The Mini-SPIN was also able to differentiate adolescents with GSP from the rest of the sample. The Mini-SPIN has good psychometrics for screening SP in adolescents from general population and may have value in screening for GSP. Copyright © 2012 Elsevier Inc. All rights reserved.

  8. Positive predictive value of additional synchronous breast lesions in whole-breast ultrasonography at the diagnosis of breast cancer: clinical and imaging factors

    International Nuclear Information System (INIS)

    Kim, Ah Hyun; Kim, Min Jung; Kim, Eun Kyung; Moon, Hee Jung; Park, Hee Jung

    2014-01-01

    To evaluate the positive predictive value (PPV) of bilateral whole-breast ultrasonography (BWBU) for detection of synchronous breast lesions on initial diagnosis of breast cancer and evaluate factors affecting the PPV of BWBU according to varying clinicoimaging factors. A total of 75 patients who had synchronous lesions with pathologic confirmation at the initial diagnosis of breast cancer during January 2007 and December 2007 were included. The clinical factors of the patients were evaluated. One observer retrospectively reviewed the imaging studies of the index breast cancer lesion and the synchronous lesion. The PPV for additional biopsy was calculated for BWBU and various clinical and imaging factors affecting the PPV for BWBU were evaluated. The overall PPV for additional biopsy was 25.7% (18 of 70). The PPV for synchronous lesions detected both on mammography and BWBU, and detected only on BWBU, was 76.9% (10 of 13) and 14.3% (7 of 49), respectively. There was no clinical factor affecting the PPV for BWBU. Among the imaging factors, ipsilateral location of the synchronous lesion to the index lesion (P=0.06) showed a marginal statistically significant correlation with malignancy in the synchronous breast lesion. A mass with calcification on mammography presentation (P<0.01), presence of calcification among the ultrasonography findings (P<0.01), and high Breast Imaging Reporting and Data System final assessment (P<0.01) were imaging factors that were associated with malignancy in the additional synchronous lesion. BWBU can detect additional synchronous malignancy at the diagnosis of breast cancer with a relatively high PPV, especially when mammography findings are correlated with ultrasonographic findings.

  9. Beyond Screening: Can the Mini-Mental State Examination be Used as an Exclusion Tool in a Memory Clinic?

    Science.gov (United States)

    Xu, Xin; Chong, Eddie; Hilal, Saima; Ikram, Mohammad Kamran; Venketasubramanian, Narayanaswamy; Chen, Christopher

    2015-11-04

    This study explores whether the Mini-Mental State Examination (MMSE) could reliably exclude definite dementia and dementia-free cases from requiring more extensive neuropsychological investigations in memory clinic settings in Singapore. Patients with memory complaints referred for possible dementia underwent the MMSE, followed by standardized neuropsychological and clinical assessments which led to a consensus diagnosis. MMSE cut-off points were derived stratified for education (less and equal/above primary level). Results show that after education stratification, using an optimal Positive Likelihood Ratio (PLR) and optimal Negative Likelihood Ratio (NLR), a higher percentage of patients were correctly identified as having dementia or dementia-free, with minimal misclassification rate. The finding suggests the MMSE can be used to exclude patients not requiring full neuropsychological assessments in a memory clinic.

  10. Measurement of the square measure of the pharynx and the positional diagnosis of airway obstruction during obstructive sleep apnea syndrome by dynamic MRI

    International Nuclear Information System (INIS)

    Ozuki, Taizo; Ohkubo, Yasuo; Abe, Kimihiko

    2000-01-01

    The purpose of this study was to apply dynamic MRI for the positional diagnosis of airway obstruction during snoring and sleep apnea and to compare the apnea hypopnea index (AHI) and the square measure of the pharynx obtained before and after laser-assisted uvula-palate-pharyngoplasty (LAUP). From December 1997 to October 1998, dynamic MRI and overnight monitoring were performed at the hospital of Tokyo Medical University on 42 patients who complained of snoring and symptoms related to sleep apnea syndrome (SAS). Of the 42 patients, four exhibited collapse at the position of the soft palate (soft palate type) as diagnosed by dynamic MRI, and four exhibited collapse at the position of the soft palate as well as the tongue (complex type). LAUP was performed on these eight patients with obstructive SAS (OSAS). After LAUP, the AHI of these eight patients with OSAS decreased significantly (p<0.05). The square measure of the pharynx of these eight patients was increased (p<0.01). The AHI of all four patients with soft-palate obstruction decreased, and the square measure of the pharynx of three of these four patients increased. The AHI of three of four patients with the complex type decreased, while the square measure of the pharynx of two of these four patients increased. (author)

  11. High positive predictive value of Gram stain on catheter-drawn blood samples for the diagnosis of catheter-related bloodstream infection in intensive care neonates.

    Science.gov (United States)

    Deleers, M; Dodémont, M; Van Overmeire, B; Hennequin, Y; Vermeylen, D; Roisin, S; Denis, O

    2016-04-01

    Catheter-related bloodstream infections (CRBSIs) remain a leading cause of healthcare-associated infections in preterm infants. Rapid and accurate methods for the diagnosis of CRBSIs are needed in order to implement timely and appropriate treatment. A retrospective study was conducted during a 7-year period (2005-2012) in the neonatal intensive care unit of the University Hospital Erasme to assess the value of Gram stain on catheter-drawn blood samples (CDBS) to predict CRBSIs. Both peripheral samples and CDBS were obtained from neonates with clinically suspected CRBSI. Gram stain, automated culture and quantitative cultures on blood agar plates were performed for each sample. The paired quantitative blood culture was used as the standard to define CRBSI. Out of 397 episodes of suspected CRBSIs, 35 were confirmed by a positive ratio of quantitative culture (>5) or a colony count of CDBS culture >100 colony-forming units (CFU)/mL. All but two of the 30 patients who had a CDBS with a positive Gram stain were confirmed as having a CRBSI. Seven patients who had a CDBS with a negative Gram stain were diagnosed as CRBSI. The sensitivity, specificity, positive predictive value and negative predictive value of Gram stain on CDBS were 80, 99.4, 93.3 and 98.1 %, respectively. Gram staining on CDBS is a viable method for rapidly (<1 h) detecting CRBSI without catheter withdrawal.

  12. Measurement of the square measure of the pharynx and the positional diagnosis of airway obstruction during obstructive sleep apnea syndrome by dynamic MRI

    Energy Technology Data Exchange (ETDEWEB)

    Ozuki, Taizo; Ohkubo, Yasuo; Abe, Kimihiko [Tokyo Medical Coll. (Japan)

    2000-11-01

    The purpose of this study was to apply dynamic MRI for the positional diagnosis of airway obstruction during snoring and sleep apnea and to compare the apnea hypopnea index (AHI) and the square measure of the pharynx obtained before and after laser-assisted uvula-palate-pharyngoplasty (LAUP). From December 1997 to October 1998, dynamic MRI and overnight monitoring were performed at the hospital of Tokyo Medical University on 42 patients who complained of snoring and symptoms related to sleep apnea syndrome (SAS). Of the 42 patients, four exhibited collapse at the position of the soft palate (soft palate type) as diagnosed by dynamic MRI, and four exhibited collapse at the position of the soft palate as well as the tongue (complex type). LAUP was performed on these eight patients with obstructive SAS (OSAS). After LAUP, the AHI of these eight patients with OSAS decreased significantly (p<0.05). The square measure of the pharynx of these eight patients was increased (p<0.01). The AHI of all four patients with soft-palate obstruction decreased, and the square measure of the pharynx of three of these four patients increased. The AHI of three of four patients with the complex type decreased, while the square measure of the pharynx of two of these four patients increased. (author)

  13. Mini-implant-supported Molar Distalization

    Directory of Open Access Journals (Sweden)

    Amit Goyal

    2012-01-01

    Full Text Available Temporary anchorage devices popularly called mini-implants or miniscrews are the latest addition to an orthodontist′s armamentarium. The following case report describes the treatment of a 16-year-old girl with a pleasant profile, moderate crowding and Angle′s Class II molar relationship. Maxillary molar distalization was planned and mini-implants were used to preserve the anterior anchorage. After 13 months of treatment, Class I molar and canine relation was achieved bilaterally and there was no anterior proclination. Thus, mini-implants provide a viable option to the clinician to carry out difficult tooth movements without any side effects.

  14. The MiniBooNE detector

    International Nuclear Information System (INIS)

    Aguilar-Arevalo, A.A.; Anderson, C.E.; Bartoszek, L.M.; Bazarko, A.O.; Brice, S.J.; Brown, B.C.; Bugel, L.; Cao, J.; Coney, L.; Conrad, J.M.; Cox, D.C.; Curioni, A.; Djurcic, Z.; Finley, D.A.; Fleming, B.T.; Ford, R.; Garcia, F.G.; Garvey, G.T.; Green, C.; Green, J.A.

    2009-01-01

    The MiniBooNE neutrino detector was designed and built to look for ν μ →ν e oscillations in the (sin 2 2θ,Δm 2 ) parameter space region where the LSND experiment reported a signal. The MiniBooNE experiment used a beam energy and baseline that were an order of magnitude larger than those of LSND so that the backgrounds and systematic errors would be completely different. This paper provides a detailed description of the design, function, and performance of the MiniBooNE detector.

  15. The MiniBooNE Detector

    OpenAIRE

    MiniBooNE Collaboration

    2008-01-01

    The MiniBooNE neutrino detector was designed and built to look for muon-neutrino to electron-neutrino oscillations in the mixing parameter space region where the LSND experiment reported a signal. The MiniBooNE experiment used a beam energy and baseline that were an order of magnitude larger than those of LSND so that the backgrounds and systematic errors would be completely different. This paper provides a detailed description of the design, function, and performance of the MiniBooNE detector.

  16. Quality Assurance Framework for Mini-Grids

    Energy Technology Data Exchange (ETDEWEB)

    Esterly, Sean; Baring-Gould, Ian; Booth, Samuel

    2017-05-04

    To address the root challenges of providing quality power to remote consumers through financially viable mini-grids, the Global Lighting and Energy Access Partnership (Global LEAP) initiative of the Clean Energy Ministerial and the U.S. Department of Energy teamed with the National Renewable Energy Laboratory (NREL) and Power Africa to develop a Quality Assurance Framework (QAF) for isolated mini-grids. The framework addresses both alternating current (AC) and direct current (DC) mini-grids, and is applicable to renewable, fossil-fuel, and hybrid systems.

  17. Psychometric properties of a sign language version of the Mini International Neuropsychiatric Interview (MINI)

    OpenAIRE

    Øhre, Beate; Saltnes, Hege; von Tetzchner, Stephen; Falkum, Erik

    2014-01-01

    Background There is a need for psychiatric assessment instruments that enable reliable diagnoses in persons with hearing loss who have sign language as their primary language. The objective of this study was to assess the validity of the Norwegian Sign Language (NSL) version of the Mini International Neuropsychiatric Interview (MINI). Methods The MINI was translated into NSL. Forty-one signing patients consecutively referred to two specialised psychiatric units were assessed with a diagnos...

  18. Spurious RF signals emitted by mini-UAVs

    NARCIS (Netherlands)

    Schleijpen, R.; Voogt, V.; Zwamborn, P.; Oever, J. van den

    2016-01-01

    This paper presents experimental work on the detection of spurious RF emissions of mini Unmanned Aerial Vehicles (mini-UAV). Many recent events have shown that mini-UAVs can be considered as a potential threat for civil security. For this reason the detection of mini-UAVs has become of interest to

  19. MINI-SLAR delivery system

    International Nuclear Information System (INIS)

    Alstein, D.

    1996-01-01

    In the Spring of 1993, a need to complete Spacer Location and Repositioning (SLAR) on the Bruce 'A', Unit 1 Reactor was identified. An alternate SLAR delivery system was required due to conversion constraints that prevented the existing Bruce SLAR System from being used in Unit 1. A Portable SLAR Delivery System called MINI-SLAR Delivery System was developed, designed and fabricated in a 14 month period, then used to successfully SLAR 109 channels. The system is a portable remotely operated Nuclear Class 1 registered fitting that is independent of the Fuelling Machine, allowing the station to continue normal Fuelling and Maintenance activities. It is designed to a Level 'D' faulted condition of HPECI Pressure thus minimizing PHT Heat Sink configuration requirements and minimizing outage set-up times. The system is based on a modular design allowing for easy fabrication, assembly and repair. It consists of a Snout Assembly, a Closure Plug Assembly, Shield Plug Assembly, SLAR Ram assembly, Work Table Assembly and Control Panel. Controls are through a Programmable Logic Controller with software tested and certified to a Software Quality Assurance of Level Ill. (author). 2 refs., 2 figs

  20. MINI-SLAR delivery system

    Energy Technology Data Exchange (ETDEWEB)

    Alstein, D [Ontario Hydro, Tiverton, ON (Canada). Bruce Nuclear Generating Station-A; Dalton, K [Spectrum Engineering, Peterborough, ON (Canada)

    1997-12-31

    In the Spring of 1993, a need to complete Spacer Location and Repositioning (SLAR) on the Bruce `A`, Unit 1 Reactor was identified. An alternate SLAR delivery system was required due to conversion constraints that prevented the existing Bruce SLAR System from being used in Unit 1. A Portable SLAR Delivery System called MINI-SLAR Delivery System was developed, designed and fabricated in a 14 month period, then used to successfully SLAR 109 channels. The system is a portable remotely operated Nuclear Class 1 registered fitting that is independent of the Fuelling Machine, allowing the station to continue normal Fuelling and Maintenance activities. It is designed to a Level `D` faulted condition of HPECI Pressure thus minimizing PHT Heat Sink configuration requirements and minimizing outage set-up times. The system is based on a modular design allowing for easy fabrication, assembly and repair. It consists of a Snout Assembly, a Closure Plug Assembly, Shield Plug Assembly, SLAR Ram assembly, Work Table Assembly and Control Panel. Controls are through a Programmable Logic Controller with software tested and certified to a Software Quality Assurance of Level Ill. (author). 2 refs., 2 figs.

  1. Analysis of MINIE2013 Explosion Air-Blast Data

    Energy Technology Data Exchange (ETDEWEB)

    Schnurr, Julie M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Univ. of Hawaii, Manoa, HI (United States); Rodgers, Arthur J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Kim, Keehoon [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ford, Sean R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ramirez, Abelardo L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-10-14

    We report analysis of air-blast overpressure measurements from the MINIE2013 explosive experiments. The MINIE2013 experiment involved a series of nearly 70 near-surface (height-ofburst, HOB, ranging from -1 to +4 m) low-yield (W=2-20 kg TNT equivalent) chemical highexplosives tests that were recorded at local distances (230 m – 28.5 km). Many of the W and HOB combinations were repeated, allowing for quantification of the variability in air-blast features and corresponding yield estimates. We measured canonical signal features (peak overpressure, impulse per unit area, and positive pulse duration) from the air-blast data and compared these to existing air-blast models. Peak overpressure measurements showed good agreement with the models at close ranges but tended to attenuate more rapidly at longer range (~ 1 km), which is likely caused by upward refraction of acoustic waves due to a negative vertical gradient of sound speed. We estimated yields of the MINIE2013 explosions using the Integrated Yield Determination Tool (IYDT). Errors of the estimated yields were on average within 30% of the reported yields, and there were no significant differences in the accuracy of the IYDT predictions grouped by yield. IYDT estimates tend to be lower than ground truth yields, possibly because of reduced overpressure amplitudes by upward refraction. Finally, we report preliminary results on a development of a new parameterized air-blast waveform.

  2. Are Ducted Mini-Splits Worth It?

    Energy Technology Data Exchange (ETDEWEB)

    Winkler, Jonathan M [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Maguire, Jeffrey B [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Metzger, Cheryn E. [Pacific Northwest National Laboratory; Zhang, Jason [Pacific Northwest National Laboratory

    2018-02-01

    Ducted mini-split heat pumps are gaining popularity in some regions of the country due to their energy-efficient specifications and their ability to be hidden from sight. Although product and install costs are typically higher than the ductless mini-split heat pumps, this technology is well worth the premium for some homeowners who do not like to see an indoor unit in their living area. Due to the interest in this technology by local utilities and homeowners, the Bonneville Power Administration (BPA) has funded the Pacific Northwest National Laboratory (PNNL) and the National Renewable Energy Laboratory (NREL) to develop capabilities within the Building Energy Optimization (BEopt) tool to model ducted mini-split heat pumps. After the fundamental capabilities were added, energy-use results could be compared to other technologies that were already in BEopt, such as zonal electric resistance heat, central air source heat pumps, and ductless mini-split heat pumps. Each of these technologies was then compared using five prototype configurations in three different BPA heating zones to determine how the ducted mini-split technology would perform under different scenarios. The result of this project was a set of EnergyPlus models representing the various prototype configurations in each climate zone. Overall, the ducted mini-split heat pumps saved about 33-60% compared to zonal electric resistance heat (with window AC systems modeled in the summer). The results also showed that the ducted mini-split systems used about 4% more energy than the ductless mini-split systems, which saved about 37-64% compared to electric zonal heat (depending on the prototype and climate).

  3. Frontoplastia mini-invasiva Mini-invasive forehead-plasty

    Directory of Open Access Journals (Sweden)

    A. Fuente del Campo

    2009-06-01

    Full Text Available Una de las causas mas importantes de la flacidez y caída de la piel y de las partes blandas de la cara es la disminución del volumen de su estructura esquelética. Un factor fundamental en la restauración del envejecimiento facial seria el poder recuperar este volumen. Dado que en la actualidad no se cuenta con un recurso efectivo para recuperar el volumen óseo, lo indicado es restaurar la relación entre las partes blandas y el volumen óseo vigente. Esta es la meta mas importante de la ritidectomía subperióstica. Con una vasta experiencia en este método y buscando minimizar las cicatrices resultantes, hemos desarrollado el enfoque mini-invasivo de este procedimiento de restauración facial. En el presente trabajo describimos la aplicación de nuestro procedimiento para la restauración de la región frontal. Desde 1998 hemos realizado este procedimiento, con diversas combinaciones y variantes y dependiendo de las necesidades de cada caso, en un total de 521 pacientes: 419 mujeres y 102 hombres de edades comprendidas entre los 45 y los 73 años. Planteamos las metas y describimos los medios para realizar este procedimiento por vía frontal, transpalpebral y combinando ambas vías, a la vez que damos orientación para lograr los objetivos del procedimiento y evitar complicaciones basándonos en la Anatomía Quirúrgica. Referimos los procedimientos auxiliares que se pueden asociar a este método y describimos los detalles del manejo postoperatorio. Los resultados obtenidos han sido en general muy satisfactorios tanto para los pacientes como para el cirujano. Mencionamos también las complicaciones observadas. En conclusión, describimos las observaciones resultantes de nuestra experiencia con este método a lo largo de 10 años, con resultados tan buenos o mejores que con la ritidectomía subperióstica abierta y el porqué es actualmente nuestro procedimiento de elección.The reduction of the bony structure of the face is the main reason

  4. Examining the reliability and validity of the Hebrew version of the Mini Mental State Examination.

    Science.gov (United States)

    Werner, P; Heinik, J; Mendel, A; Reicher, B; Bleich, A

    1999-10-01

    The Mini Mental State Examination is used worldwide for the screening and diagnosis of dementia. The aim of the present study was to examine the reliability and validity of the Hebrew version of the Mini Mental State Examination. The Hebrew version of the Mini Mental State Examination was administered to 36 demented and 19 non-demented elderly persons. Test-retest reliability scores were calculated as exact agreement rates, and ranged from good to excellent for all the items. Strong convergent validity, as measured by the correlation between the MMSE and the CAM-COG (r = 0.94), was found. Good predictive value was observed as over three-quarters of the participants were correctly classified as demented or non-demented. The Hebrew version of the MMSE was found to be a useful and valid instrument for the determination of dementia in the elderly population.

  5. [Bone remodeling and modeling/mini-modeling.

    Science.gov (United States)

    Hasegawa, Tomoka; Amizuka, Norio

    Modeling, adapting structures to loading by changing bone size and shapes, often takes place in bone of the fetal and developmental stages, while bone remodeling-replacement of old bone into new bone-is predominant in the adult stage. Modeling can be divided into macro-modeling(macroscopic modeling)and mini-modeling(microscopic modeling). In the cellular process of mini-modeling, unlike bone remodeling, bone lining cells, i.e., resting flattened osteoblasts covering bone surfaces will become active form of osteoblasts, and then, deposit new bone onto the old bone without mediating osteoclastic bone resorption. Among the drugs for osteoporotic treatment, eldecalcitol(a vitamin D3 analog)and teriparatide(human PTH[1-34])could show mini-modeling based bone formation. Histologically, mature, active form of osteoblasts are localized on the new bone induced by mini-modeling, however, only a few cell layer of preosteoblasts are formed over the newly-formed bone, and accordingly, few osteoclasts are present in the region of mini-modeling. In this review, histological characteristics of bone remodeling and modeling including mini-modeling will be introduced.

  6. MiniCNT - A Tabletop Stellarator

    Science.gov (United States)

    Dugan, Chris; Pedersen, Thomas; Berkery, John

    2006-10-01

    MiniCNT is a scaled down version of the Columbia Non-Neutral Torus, a stellarator built to study confinement of non-neutral plasmas on magnetic surfaces. MiniCNT is a glass vacuum chamber capable of holding pressures six orders of magnitude below atmospheric pressure. Unlike CNT, in which plasmas are invisible, MiniCNT allows some collisions with neutrals, causing it to glow. Using two twelve-volt car batteries to power four magnetic coils, MiniCNT generates a 0.02 Tesla magnetic field. While CNT, being larger, is obviously more accurate, there are multiple benefits in MiniCNT. First, it is more flexible and can be adjusted to fit many scenarios easily. The car batteries can be switched for other power sources, the coils can be realigned, and the chamber can be pumped to various pressures of various gases. Also, it is visually accessible; while CNT has glass viewing ports and its plasma is dark, MiniCNT is made of glass and its plasma glows, allowing visualization of the magnetic surfaces.

  7. The Psychometrics of the Mini-K.

    Science.gov (United States)

    Richardson, George B; Chen, Ching-Chen; Dai, Chia-Liang; Brubaker, Michael D; Nedelec, Joseph L

    2017-01-01

    Many published studies have employed the Mini-K to measure a single fast-slow life history dimension. However, the internal structure of the Mini-K has not been determined and it is not clear that a single higher order K-factor fits the data. It is also not clear that the Mini-K is measurement invariant across groups such as the sexes. To establish the construct validity of K as well as the broader usefulness of applying life history theory to humans, it is crucial that these psychometric issues are addressed as a part of measure validation efforts. Here we report on three studies that used latent variable modeling and data drawn from two college student samples ( ns = 361 and 300) to elucidate the psychometrics of the Mini-K. We found that (a) the Mini-K had a six dimensional first-order structure, (b) the K-factor provided a parsimonious explanation of the associations among the lower order factors at no significant cost to fit, (c) the Mini-K measured the same K-factor across the sexes, (d) K-factor means did not have the same meaning across the sexes and thus the first-order factors should be used in studies of mean sex differences, and finally, (e) the K-factor was only associated with environment and aspects of mating competition in females. Implications and future directions for life history research are discussed.

  8. The Norwegian version of the Mini-Mental Adjustment to Cancer Scale: factor structure and psychometric properties.

    Science.gov (United States)

    Bredal, Inger Schou

    2010-02-01

    The object of the study was to examine the factor structure and the psychometric properties of the Mini-Mental Adjustment to Cancer Scale (Mini-MAC) among a large sample of Norwegian breast cancer patients. A total of 402 patients with breast cancer completed the Mini-MAC. Principal component analysis with varimax rotion confirmed four factors. Three had psychometric properties to the original Mini-MAC Helpless-Hopeless (HH), Anxious Preoccupation (AP) and Cognitive Avoidance (CA) subscales. The fourth, named Positive Attitude (PA) combined the Fighting Spirit (FS) and the Fatalism subscales of the original Mini-MAC. Construct validities were assessed by examining the interscale correlations as well as the correlations between the Mini-MAC subscales and the HADS subscales scores. Internal consistency of the five subscales was satisfactory for the original (HH, AP, CA, FA, coefficients=0.60-0.83), except for the FS subscale (coefficient=21). In view of the low internal reliability for the Norwegian Mini-MAC FS subscale coefficient; it appears to be more appropriate to use the Norwegian Mini-MAC as a four-factor model. If researcher or clinicians in Norway use the five-factor model, they should take great care when interpreting the fighting spirit subscale.

  9. Screening for Dementia in Older Adults: Comparison of Mini-Mental State Examination, Mini-Cog, Clock Drawing Test and AD8.

    Science.gov (United States)

    Yang, Li; Yan, Jing; Jin, Xiaoqing; Jin, Yu; Yu, Wei; Xu, Shanhu; Wu, Haibin

    2016-01-01

    This study was conducted to estimate screening performance of dementia screening tools including Mini-Mental State Examination (MMSE), Mini-Cog, Clock Drawing Test (CDT) and Ascertain Dementia 8 questionnaire (AD8) for older adults. 2015 participants aged 65 years or more in eastern China were enrolled. 4 screening tests were administered and scored by specifically trained psychiatrists. We used data from two-by-two tables to calculate the sensitivity, specificity, and positive and negative predictive values (PPV/NPV). Our study showed that dementia was highly prevalent among elderly in Zhejiang province. The Mini-Cog, with excellent screening characteristics and spending less time, could be considered to be used as a screening tool among communities to help to diagnose dementia early.

  10. Clock Drawing Test and the diagnosis of amnestic mild cognitive impairment: can more detailed scoring systems do the work?

    Science.gov (United States)

    Rubínová, Eva; Nikolai, Tomáš; Marková, Hana; Siffelová, Kamila; Laczó, Jan; Hort, Jakub; Vyhnálek, Martin

    2014-01-01

    The Clock Drawing Test is a frequently used cognitive screening test with several scoring systems in elderly populations. We compare simple and complex scoring systems and evaluate the usefulness of the combination of the Clock Drawing Test with the Mini-Mental State Examination to detect patients with mild cognitive impairment. Patients with amnestic mild cognitive impairment (n = 48) and age- and education-matched controls (n = 48) underwent neuropsychological examinations, including the Clock Drawing Test and the Mini-Mental State Examination. Clock drawings were scored by three blinded raters using one simple (6-point scale) and two complex (17- and 18-point scales) systems. The sensitivity and specificity of these scoring systems used alone and in combination with the Mini-Mental State Examination were determined. Complex scoring systems, but not the simple scoring system, were significant predictors of the amnestic mild cognitive impairment diagnosis in logistic regression analysis. At equal levels of sensitivity (87.5%), the Mini-Mental State Examination showed higher specificity (31.3%, compared with 12.5% for the 17-point Clock Drawing Test scoring scale). The combination of Clock Drawing Test and Mini-Mental State Examination scores increased the area under the curve (0.72; p Drawing Test did not differentiate between healthy elderly and patients with amnestic mild cognitive impairment in our sample. Complex scoring systems were slightly more efficient, yet still were characterized by high rates of false-positive results. We found psychometric improvement using combined scores from the Mini-Mental State Examination and the Clock Drawing Test when complex scoring systems were used. The results of this study support the benefit of using combined scores from simple methods.

  11. Canadian Sleep Society/Canadian Thoracic Society position paper on the use of portable monitoring for the diagnosis of obstructive sleep apnea/hypopnea in adults

    Directory of Open Access Journals (Sweden)

    Adam Blackman

    2010-01-01

    Full Text Available The present position paper on the use of portable monitoring (PM as a diagnostic tool for obstructive sleep apnea/hypopnea (OSAH in adults was based on consensus and expert opinion regarding best practice standards from stakeholders across Canada. These recommendations were prepared to guide appropriate clinical use of this new technology and to ensure that quality assurance standards are adhered to. Clinical guidelines for the use of PM for the diagnosis and management of OSAH as an alternative to in-laboratory polysomnography published by the American Academy of Sleep Medicine Portable Monitoring Task Force were used to tailor our recommendations to address the following: indications; methodology including physician involvement, physician and technical staff qualifications, and follow-up requirements; technical considerations; quality assurance; and conflict of interest guidelines. When used appropriately under the supervision of a physician with training in sleep medicine, and in conjunction with a comprehensive sleep evaluation, PM may expedite treatment when there is a high clinical suspicion of OSAH.

  12. Quality Assurance Framework for Mini-Grids

    Energy Technology Data Exchange (ETDEWEB)

    Baring-Gould, Ian [National Renewable Energy Lab. (NREL), Golden, CO (United States); Burman, Kari [National Renewable Energy Lab. (NREL), Golden, CO (United States); Singh, Mohit [National Renewable Energy Lab. (NREL), Golden, CO (United States); Esterly, Sean [National Renewable Energy Lab. (NREL), Golden, CO (United States); Mutiso, Rose [US Department of Energy, Washington, DC (United States); McGregor, Caroline [US Department of Energy, Washington, DC (United States)

    2016-11-01

    Providing clean and affordable energy services to the more than 1 billion people globally who lack access to electricity is a critical driver for poverty reduction, economic development, improved health, and social outcomes. More than 84% of populations without electricity are located in rural areas where traditional grid extension may not be cost-effective; therefore, distributed energy solutions such as mini-grids are critical. To address some of the root challenges of providing safe, quality, and financially viable mini-grid power systems to remote customers, the U.S. Department of Energy (DOE) teamed with the National Renewable Energy Laboratory (NREL) to develop a Quality Assurance Framework (QAF) for isolated mini-grids. The QAF for mini-grids aims to address some root challenges of providing safe, quality, and affordable power to remote customers via financially viable mini-grids through two key components: (1) Levels of service: Defines a standard set of tiers of end-user service and links them to technical parameters of power quality, power availability, and power reliability. These levels of service span the entire energy ladder, from basic energy service to high-quality, high-reliability, and high-availability service (often considered 'grid parity'); (2) Accountability and performance reporting framework: Provides a clear process of validating power delivery by providing trusted information to customers, funders, and/or regulators. The performance reporting protocol can also serve as a robust monitoring and evaluation tool for mini-grid operators and funding organizations. The QAF will provide a flexible alternative to rigid top-down standards for mini-grids in energy access contexts, outlining tiers of end-user service and linking them to relevant technical parameters. In addition, data generated through implementation of the QAF will provide the foundation for comparisons across projects, assessment of impacts, and greater confidence that

  13. Positive predictive value of additional synchronous breast lesions in whole-breast ultrasonography at the diagnosis of breast cancer: clinical and imaging factors

    Directory of Open Access Journals (Sweden)

    Ah Hyun Kim

    2014-07-01

    Conclusion: BWBU can detect additional synchronous malignancy at the diagnosis of breast cancer with a relatively high PPV, especially when mammography findings are correlated with ultrasonographic findings.

  14. Diagnosis of blood culture-negative endocarditis and clinical comparison between blood culture-negative and blood culture-positive cases.

    Science.gov (United States)

    Lamas, Cristiane C; Fournier, Pierre-Edouard; Zappa, Monica; Brandão, Tatiana J D; Januário-da-Silva, Carolina A; Correia, Marcelo G; Barbosa, Giovanna Ianini F; Golebiovski, Wilma F; Weksler, Clara; Lepidi, Hubert; Raoult, Didier

    2016-08-01

    To analyze the clinical characteristics of blood culture-negative endocarditis (BCNE) and how it compares to those of blood culture-positive endocarditis (BCPE) cases and show how molecular tools helped establish the etiology in BCNE. Adult patients with definite infective endocarditis (IE) and having valve surgery were included. Valves were studied by polymerase chain reaction (PCR). Statistical analysis compared BCNE and BCPE. One hundred and thirty-one patients were included; 53 (40 %) had BCNE. The mean age was 45 ± 16 years; 33 (62 %) were male. BCNE was community-acquired in 41 (79 %). Most patients were referred from other hospitals (38, 73 %). Presentation was subacute in 34 (65 %), with fever in 47/53 (90 %) and a new regurgitant murmur in 34/42 (81 %). Native valves were affected in 74 %, mostly left-sided. All echocardiograms showed major criteria for IE. Antibiotics were used prior to BC collection in 31/42 (74 %). Definite histological diagnosis was established for 35/50 (70 %) valves. PCR showed oralis group streptococci in 21 (54 %), S. aureus in 3 (7.7 %), gallolyticus group streptococci in 2 (5.1 %), Coxiella burnetii in 1 (2.5 %) and Rhizobium sp. in 1 (2.5 %). In-hospital mortality was 9/53 (17 %). Fever (p = 0.06, OR 4.7, CI 0.91-24.38) and embolic complications (p = 0.003, OR 3.3, CI 1.55-6.82) were more frequent in BCPE cases, while new acute regurgitation (p = 0.05, OR 0.3, CI 0.098-0.996) and heart failure (p = 0.02, OR 0.3, CI 0.13-0.79) were less so. BCNE resulted mostly from prior antibiotics and was associated with severe hemodynamic compromise. Valve histopathology and PCR were useful in confirming the diagnosis and pointing to the etiology of BCNE.

  15. Psychometric properties of a sign language version of the Mini International Neuropsychiatric Interview (MINI).

    Science.gov (United States)

    Øhre, Beate; Saltnes, Hege; von Tetzchner, Stephen; Falkum, Erik

    2014-05-22

    There is a need for psychiatric assessment instruments that enable reliable diagnoses in persons with hearing loss who have sign language as their primary language. The objective of this study was to assess the validity of the Norwegian Sign Language (NSL) version of the Mini International Neuropsychiatric Interview (MINI). The MINI was translated into NSL. Forty-one signing patients consecutively referred to two specialised psychiatric units were assessed with a diagnostic interview by clinical experts and with the MINI. Inter-rater reliability was assessed with Cohen's kappa and "observed agreement". There was 65% agreement between MINI diagnoses and clinical expert diagnoses. Kappa values indicated fair to moderate agreement, and observed agreement was above 76% for all diagnoses. The MINI diagnosed more co-morbid conditions than did the clinical expert interview (mean diagnoses: 1.9 versus 1.2). Kappa values indicated moderate to substantial agreement, and "observed agreement" was above 88%. The NSL version performs similarly to other MINI versions and demonstrates adequate reliability and validity as a diagnostic instrument for assessing mental disorders in persons who have sign language as their primary and preferred language.

  16. Psychometric properties of a sign language version of the Mini International Neuropsychiatric Interview (MINI)

    Science.gov (United States)

    2014-01-01

    Background There is a need for psychiatric assessment instruments that enable reliable diagnoses in persons with hearing loss who have sign language as their primary language. The objective of this study was to assess the validity of the Norwegian Sign Language (NSL) version of the Mini International Neuropsychiatric Interview (MINI). Methods The MINI was translated into NSL. Forty-one signing patients consecutively referred to two specialised psychiatric units were assessed with a diagnostic interview by clinical experts and with the MINI. Inter-rater reliability was assessed with Cohen’s kappa and “observed agreement”. Results There was 65% agreement between MINI diagnoses and clinical expert diagnoses. Kappa values indicated fair to moderate agreement, and observed agreement was above 76% for all diagnoses. The MINI diagnosed more co-morbid conditions than did the clinical expert interview (mean diagnoses: 1.9 versus 1.2). Kappa values indicated moderate to substantial agreement, and “observed agreement” was above 88%. Conclusion The NSL version performs similarly to other MINI versions and demonstrates adequate reliability and validity as a diagnostic instrument for assessing mental disorders in persons who have sign language as their primary and preferred language. PMID:24886297

  17. Fibrous mini-collagens in hydra nematocysts.

    Science.gov (United States)

    Holstein, T W; Benoit, M; Herder, G V; David, C N; Wanner, G; Gaub, H E

    1994-07-15

    Nematocysts (cnidocysts) are exocytotic organelles found in all cnidarians. Here, atomic force microscopy and field emission scanning electron microscopy reveal the structure of the nematocyst capsule wall. The outer wall consists of globular proteins of unknown function. The inner wall consists of bundles of collagen-like fibrils having a spacing of 50 to 100 nanometers and cross-striations at intervals of 32 nanometers. The fibrils consist of polymers of "mini-collagens," which are abundant in the nematocysts of Hydra. The distinct pattern of mini-collagen fibers in the inner wall can provide the tensile strength necessary to withstand the high osmotic pressure (15 megapascals) in the capsules.

  18. Development on mini X-ray diode

    International Nuclear Information System (INIS)

    Jiang Shaoen; Sun Kexu; Peng Nengling; Huang Tianxuan; Cui Yanli; Yi Rongqing; Chen Jiusen

    2004-01-01

    The mini X-ray diode (M-XRD) was developed, and was used in mini soft X-ray spectrometer. Compared with traditional XRD, M-XRD's volume reduces to 1/30. M-XRD's property was experimentally examined on Shenguang II laser facility. The experimental results indicated that the temporal response and sensitivity of M-XRD are basically consistent with traditional XRD. The equivalent circuit of XRD was analyzed, and its response time and linear saturated current were calculated. (authors)

  19. Circular RNAs as Promising Biomarkers: A mini-review

    Directory of Open Access Journals (Sweden)

    Nadiah Abu

    2016-08-01

    Full Text Available The interest in circular RNAs has resurfaced in the past few years. What was considered as junk for nearly two decades is now one of the most interesting molecules. Circular RNAs are non-coding RNAs that are formed by back-splicing events and have covalently closed loops with no poly-adenylated tails. The regulation of circular RNAs is distinctive and they are selectively abundant in different types of tissues. Based on the current knowledge of circular RNAs, these molecules have the potential to be the next big thing especially as biomarkers for different diseases. This mini-review attempts to concisely look at the biology of circular RNAs, the putative functional activities, the prevalence of circular RNAs, and the possible role of circular RNA as biomarkers for diagnosis or measuring drug response.

  20. Impact on ART initiation of point-of-care CD4 testing at HIV diagnosis among HIV-positive youth in Khayelitsha, South Africa.

    Science.gov (United States)

    Patten, Gabriela E M; Wilkinson, Lynne; Conradie, Karien; Isaakidis, Petros; Harries, Anthony D; Edginton, Mary E; De Azevedo, Virginia; van Cutsem, Gilles

    2013-07-04

    Despite the rapid expansion of antiretroviral therapy (ART) programmes in developing countries, pre-treatment losses from care remain a challenge to improving access to treatment. Youth and adolescents have been identified as a particularly vulnerable group, at greater risk of loss from both pre-ART and ART care. Point-of-care (POC) CD4 testing has shown promising results in improving linkage to ART care. In Khayelitsha township, South Africa, POC CD4 testing was implemented at a clinic designated for youth aged 12-25 years. We assessed whether there was an associated reduction in attrition between HIV testing, assessment for eligibility and ART initiation. A before-and-after observational study was conducted using routinely collected data. These were collected on patients from May 2010 to April 2011 (Group A) when baseline CD4 count testing was performed in a laboratory and results were returned to the clinic within two weeks. Same-day POC CD4 testing was implemented in June 2011, and data were collected on patients from August 2011 to July 2012 (Group B). A total of 272 and 304 youth tested HIV-positive in Group A and Group B, respectively. Group B patients were twice as likely to have their ART eligibility assessed compared to Group A patients: 275 (90%) vs. 183 (67%) [relative risk (RR)=2.4, 95% CI: 1.8-3.4, pART was 50% and 44% (p=0.6) in Groups B and A, respectively; and 50% and 43% (p=0.5) when restricted to patients with baseline CD4 count≤250 cells/µL. Time between HIV-testing and ART initiation was reduced from 36 to 28 days (p=0.6). POC CD4 testing significantly improved assessment for ART eligibility. The improvement in the proportion initiating ART and the reduction in time to initiation was not significant due to sample size limitations. POC CD4 testing reduced attrition between HIV-testing and assessment of ART eligibility. Strategies to improve uptake of ART are needed, possibly by improving patient support for HIV-positive youth immediately

  1. Low power consumption mini rotary actuator with SMA wires

    Science.gov (United States)

    Manfredi, Luigi; Huan, Yu; Cuschieri, Alfred

    2017-11-01

    Shape memory alloys (SMAs) are smart materials widely used as actuators for their high power to weight ratio despite their well-known low energy efficiency and limited mechanical bandwidth. For robotic applications, SMAs exhibit limitations due to high power consumption and limited stroke, varying from 4% to 7% of the total length. Hysteresis, during the contraction and extension cycle, requires a complex control algorithm. On the positive side, the small size and low weight are eminently suited for the design of mini actuators for robotic platforms. This paper describes the design and construction of a light weight and low power consuming mini rotary actuator with on-board contact-less position and force sensors. The design is specifically intended to reduce (i) energy consumption, (ii) dimensions of the sensory system, and (iii) provide a simple control without any need for SMA characterisation. The torque produced is controlled by on-board force sensors. Experiments were performed to investigate the energy consumption and performance (step and sinusoidal angle profiles with a frequency varying from 0.5 to 10 Hz and maximal amplitude of {15}\\circ ). We describe a transient capacitor effect related to the SMA wires during the sinusoidal profile when the active SMA wire is powered and the antagonist one switched-off, resulting in a transient current time varying from 300 to 400 ms.

  2. A t (11; 22 (p13; q12 EWS-WT 1 positive desmoplastic small round cell tumor of the maxilla: An unusual case indicating the role of molecular diagnosis in round cell sarcomas

    Directory of Open Access Journals (Sweden)

    Rekhi B

    2010-01-01

    Full Text Available A desmoplastic small round cell tumor (DSRCT is an uncommon tumor characterized by polyphenotypic expression and a specific reciprocal translocation t (11; 22 (p13; q12. It has been rarely identified in the head and neck region. Herein, we describe a DSRCT in the maxilla of a young man, who was initially diagnosed with a primitive neuroectodermal tumor (PNET, based on histopathological appearance of a round cell tumor, with MIC2 and -FLI-1 positivity, on immunohistochemistry (IHC. Diagnosis of a DSRCT was confirmed on molecular analysis with positive -RT-PCR and sequencing results for EWS-WT1 transcript and negativity for EWS-FL1. The case is presented to highlight the value of molecular diagnosis in round cell sarcomas at uncommon sites, especially when similar IHC markers can be expressed in a PNET and a DSRCT. An exact diagnosis of a round cell sarcoma has a therapeutic relevance.

  3. Current Status of the MiniBooNE Experiment

    OpenAIRE

    Ray, H.; collaboration, for the MiniBooNE

    2004-01-01

    MiniBooNE is an experiment designed to refute or confirm the LSND anti-nu_mu -> anti-nu_e oscillation result. MiniBooNE will look for oscillations of nu_mu -> nu_e in a closed-box appearance analysis. MiniBooNE began collecting data in 2002, and is expected to continue data taking through 2005. Current MiniBooNE results are presented.

  4. Mini-implantes ortodônticos como auxiliares da fase de retração anterior Orthodontic mini-implants assisting the anterior retraction phase

    Directory of Open Access Journals (Sweden)

    Carlo Marassi

    2008-10-01

    Full Text Available INTRODUÇÃO: os mini-implantes ortodônticos se estabeleceram como um importante método de ancoragem e vêm auxiliando os ortodontistas nas várias etapas do tratamento ortodôntico, eliminando, em grande parte, a necessidade de colaboração dos pacientes e tornando os resultados mais previsíveis. OBJETIVO: este artigo descreve os principais aspectos do uso dos mini-implantes como auxiliares da fase de retração anterior, trazendo considerações sobre suas indicações, quantidade de movimentação dos dentes anteriores, os vetores de força de retração, o controle vertical, o posicionamento dos mini-implantes, os tipos de apoio na região anterior e a força a ser utilizada. São citados os sítios de instalação mais usados para a retração anterior e abordados fatores que deverão ser controlados durante o fechamento de espaço. Por fim, são citadas algumas considerações clínicas sobre o uso dos mini-implantes nessa importante fase do tratamento ortodôntico.INTRODUCTION: The use of orthodontic mini-implants has settled as an important anchorage method and is aiding the orthodontists in the several stages of the treatment, largely eliminating the need of patients' compliance, and turning the results more predictable. AIM: This article describes the main aspects of the use of mini-implants as auxiliaries on the retraction phase of the anterior teeth, bringing considerations about their indications, amount of movement of the anterior teeth, the vectors of retraction force, the vertical control and evaluation of the incisors vestibulolingual tipping, the positioning of the mini-implants, the support types in the anterior area and the force to be applied. The placement sites best used for the anterior retraction are mentioned, and the factors that should be controlled during the space closure are approached. Lastly, some clinical considerations on the use of mini-implants in such important phase of the orthodontic treatment are

  5. Mini-Sniffer II in Flight

    Science.gov (United States)

    1976-01-01

    This photograph shows the second Mini-Sniffer undergoing flight testing over Rogers Dry Lake in Edwards, California. This version of the Mini-Sniffer lacked the canard of the original version and had wing tips and tail booms added. The Mini-Sniffer was a remotely controlled, propeller-driven vehicle developed at the NASA Flight Research Center (which became the Dryden Flight Research Center, Edwards, California, in 1976) as a potential platform to sample the upper atmosphere for pollution. The vehicle, flown from 1975 to 1977, was one of the earliest attempts by NASA to develop an aircraft that could sense turbulence and measure natural and human-produced atmospheric pollutants at altitudes above 80,000 feet with a variable-load propeller that was never flight-tested. Three Mini-Sniffer vehicles were built. The number 1 Mini-Sniffer vehicle had swept wings with a span of 18 feet and canards on the nose. It flew 12 flights with the gas-powered engine at low altitudes of around 2,500 feet. The number 1 vehicle was then modified into version number 2 by removing the canards and wing rudders and adding wing tips and tail booms. Twenty flights were made with this version, up to altitudes of 20,000 feet. The number 3 vehicle had a longer fuselage, was lighter in weight, and was powered by the non-air-breathing hydrazine engine designed by NASA's Johnson Space Center in Houston, Texas. This version was designed to fly a 25-pound payload to an altitude of 70,000 feet for one hour or to climb to 90,000 feet and glide back. The number 3 Mini-Sniffer made one flight to 20,000 feet and was not flown again because of a hydrazine leak problem. All three versions used a pusher propeller to free the nose area for an atmospheric-sampling payload. At various times the Mini-Sniffer has been considered for exploration in the carbon dioxide atmosphere of the planet Mars, where the gravity (38 percent of that on Earth) would reduce the horsepower needed for flight.

  6. Validação da versão em português do Mini-Inventário de Fobia Social (Mini-SPIN Validation of the portuguese version of the Mini-Social Phobia Inventory (Mini-SPIN

    Directory of Open Access Journals (Sweden)

    Gustavo José Fonseca D'El Rey

    2009-12-01

    Full Text Available A fobia social (também conhecida como transtorno de ansiedade social é um grave transtorno mental que traz sofrimento e incapacitação. O objetivo deste estudo foi validar para a língua portuguesa o Mini-Inventário de Fobia Social (Mini-SPIN em uma amostra da população. Foi realizado um estudo da validade discriminativa do Mini-SPIN em uma amostra de 644 pessoas (grupo positivo para o Mini-SPIN: n = 218 e grupo controle/negativo: n = 426 de um estudo de prevalência de transtornos de ansiedade na cidade de Santo André (SP. A versão em português do Mini-SPIN (com escore de 6 pontos, sugerido na versão original em inglês demonstrou uma sensibilidade de 95,0%, especificidade de 80,3%, valor preditivo positivo de 52,8%, valor preditivo negativo de 98,6% e taxa de classificação incorreta de 16,9%. Com escores de 7 pontos, foi observado um aumento na especificidade e no valor preditivo positivo (88,6% e 62,7%, sendo que a sensibilidade e o valor preditivo negativo (84,8% e 96,2% mantiveram-se altos. A versão em português do Mini-SPIN apresentou qualidades psicométricas satisfatórias em termos de validade discriminativa. Neste estudo, o ponto de corte igual a 7 mostrou-se mais adequado para a identificação da fobia social generalizada.Social phobia (also known as social anxiety disorder is a severe mental disorder that brings distress and disability. The aim of this study was validate to the Portuguese language the Mini-Social Phobia Inventory (Mini-SPIN in a populational sample. We performed a discriminative validity study of the Mini-SPIN in a sample of 644 subjects (Mini-SPIN positive group: n = 218 and control/negative group: n = 426 of a study of anxiety disorders' prevalence in the city of Santo André-SP. The Portuguese version of the Mini-SPIN (with score of 6 points, suggested in the original English version demonstrated a sensitivity of 95.0%, specificity of 80.3%, positive predictive value of 52.8%, negative predictive

  7. The Individual Features Of Indonesian-Chinese Mini-Novels

    Directory of Open Access Journals (Sweden)

    Ma Feng

    2011-11-01

    Full Text Available This article talks about mini-novels in the new period of Indonesian Chinese Literature. Through the overall developing trend of mini-novels’ corpuses, analyzes the individual creative features: firstly, the humor of Mo Mingmiao’s Mini-novels; secondly, the compassion of Xiao Xing’s Mini-novels; thirdly, Yuan Ni’s emotional sonata of The Lost Key-ring. By combination of themes and techniques of the three mini-novels corpuses, the article focuses on the analysis of three writers’ distinctive writing style.

  8. Functional Movements in Japanese Mini-Basketball Players

    Directory of Open Access Journals (Sweden)

    Kuzuhara Kenji

    2018-03-01

    Full Text Available Functional movement screen (FMS has been used to establish normative data and determine potential injury risk for young adults and athletes, but there are few data in elementary school-age children. The purpose of this study was to establish fundamental values for the FMS in elementary school-age mini-basketball players. Secondary purposes were to examine relationships between functional movement patterns and age, peak height velocity (PHV, and body mass index (BMI, and to compare functional movement patterns between boys and girls and between individuals with and without a history of injury. The mean composite FMS score was 16.5 ± 2.2 (16.5 ± 2.4 for boys, 16.5 ± 1.7 for girls. The composite FMS score was positively correlated with age (r = .312 and negatively correlated with the BMI (r = − .371. However, the FMS score was not correlated with PHV or with PHV age. The FMS score was not different between boys and girls or between individuals who reported a previous injury and those who did not. However, boys in the mini-basketball teams performed better than girls on the trunk stability push-up and rotary stability tests. Age and the body mass index were significantly associated with better and poorer functional movement, respectively.

  9. Mini-Sniffer III on Lakebed

    Science.gov (United States)

    1976-01-01

    The third remotely-piloted Mini-Sniffer research vehicle rests on the lakebed adjacent to the Dryden Flight Research Center, Edwards, California. This view shows the wing shape, hydrazine engine, and the tail booms. The Mini-Sniffer was a remotely controlled, propeller-driven vehicle developed at the NASA Flight Research Center (which became the Dryden Flight Research Center, Edwards, California, in 1976) as a potential platform to sample the upper atmosphere for pollution. The vehicle, flown from 1975 to 1977, was one of the earliest attempts by NASA to develop an aircraft that could sense turbulence and measure natural and human-produced atmospheric pollutants at altitudes above 80,000 feet with a variable-load propeller that was never flight-tested. Three Mini-Sniffer vehicles were built. The number 1 Mini-Sniffer vehicle had swept wings with a span of 18 feet and canards on the nose. It flew 12 flights with the gas-powered engine at low altitudes of around 2,500 feet. The number 1 vehicle was then modified into version number 2 by removing the canards and wing rudders and adding wing tips and tail booms. Twenty flights were made with this version, up to altitudes of 20,000 feet. The number 3 vehicle had a longer fuselage, was lighter in weight, and was powered by the non-air-breathing hydrazine engine designed by NASA's Johnson Space Center in Houston, Texas. This version was designed to fly a 25-pound payload to an altitude of 70,000 feet for one hour or to climb to 90,000 feet and glide back. The number 3 Mini-Sniffer made one flight to 20,000 feet and was not flown again because of a hydrazine leak problem. All three versions used a pusher propeller to free the nose area for an atmospheric-sampling payload. At various times the Mini-Sniffer has been considered for exploration in the carbon dioxide atmosphere of the planet Mars, where the gravity (38 percent of that on Earth) would reduce the horsepower needed for flight.

  10. 10-minute delayed recall from the modified mini-mental state test predicts Alzheimer's disease pathology.

    Science.gov (United States)

    Lyness, Scott A; Lee, Ae Young; Zarow, Chris; Teng, Evelyn L; Chui, Helena C

    2014-01-01

    We compared the sensitivity and specificity of two delayed recall scores from the Modified Mini-Mental State (3MS) test with consensus clinical diagnosis to differentiate cognitive impairment due to Alzheimer's disease (AD) versus non-AD pathologies. At a memory disorders clinic, 117 cognitively impaired patients were administered a baseline 3MS test and received a contemporaneous consensus clinical diagnosis. Their brains were examined after death about 5 years later. Using logistic regression with forward selection to predict pathologically defined AD versus non-AD, 10-min delayed recall entered first (p = 0.001), followed by clinical diagnosis (p = 0.02); 1-min delayed recall did not enter. 10-min delayed recall scores ≤4 (score range = 0-9) were 87% sensitive and 47% specific in predicting AD pathology; consensus clinical diagnosis was 82% sensitive and 45% specific. For the 57 patients whose initial Mini-Mental State Examination scores were ≥19 (the median), 3MS 10-min delayed recall scores ≤4 showed some loss of sensitivity (80%) but a substantial gain in specificity (77%). In conclusion, 10-min delayed recall score on the brief 3MS test distinguished between AD versus non-AD pathology about 5 years before death at least as well as consensus clinical diagnosis that requires much more comprehensive information and complex deliberation.

  11. Summer Mini Atomiade in June 2016

    CERN Multimedia

    2016-01-01

    The Mini Atomiade are coming to CERN! Members of Clubs supported by the CERN Staff Association and in conjunction with ASCERI (Association of the Sports Communities of the European Research Institutes) will be organising the summer games at the beginning of June.   ASCERI aims to contribute to a united Europe through regular sports meetings, bringing together members of public Research Institutes at European level. The Association's members come from over 40 Research Institutes spanning 16 countries. Numerous sports and leisure activities are represented at regular events and each tournament is organised by a different research institute.  Clubs in conjunction with the CERN Staff Association have sent teams to previous winter and summer games and now, the CERN Club’s Coordination Committee (CCC) has taken on the challenge of organising a Mini Atomiade from Friday 3 June to Monday 6 June 2016 in Divonne-les-Bains. The ga...

  12. ETFAD/EADV Eczema task force 2015 position paper on diagnosis and treatment of atopic dermatitis in adult and paediatric patients

    NARCIS (Netherlands)

    Wollenberg, A; Oranje, A; Deleuran, M; Simon, D; Szalai, Z; Kunz, B; Svensson, A; Barbarot, S; von Kobyletzki, L; Taieb, A; de Bruin-Weller, M; Werfel, T; Trzeciak, M; Vestergard, C; Ring, J; Darsow, U

    2016-01-01

    Atopic dermatitis (AD) is a clinically defined, highly pruritic, chronic inflammatory skin disease of children and adults. The diagnosis is made using evaluated clinical criteria. Disease activity is best measured with a composite score assessing both objective signs and subjective symptoms, such as

  13. 'Mini' total body irradiation and allogeneic bone marrow transplantation

    International Nuclear Information System (INIS)

    Gocheva, L.; Sergieva, K.; Koleva, I.; Avramova, V.; Vassileva, V.; Georgieva, S.; Sultanov, B.

    2006-01-01

    Full text: The total body irradiation (TBI) combined with intensive chemotherapy plays an important role in the preparation of patients for bone marrow transplantation (BMT). The first autologous BMT in Bulgaria was performed in 1997 in the Specialized Pediatric Hospital for Active Treatment (SPHAT) of oncohematological diseases. The first TBI, followed by allogeneic BMT, was carried out in 2002 in the 'Queen Giovanna' University Hospital, after which its routine application as a basic form of large field radiotherapy and a main stage of the conditioning regimen for BMT was started. Fourteen allogeneic BMTs including TBI as a basic conditioning regimen have been performed till May 2006. The objective of the present report is to present the first clinical observations in the Bulgarian oncological practice on 'mini' TBI followed by allogeneic blood stem cell transplantation. During the period October 2005 - May 2006, 'mini' TBI followed by allogeneic BMT was carried out for two patients of the age 43 and 50 years. The diagnosis of both patients was acute non-lymphoblastic leukemia, in the remission stage, after one relapse, respectively. Intensive preceding chemotherapy was applied for both patients. A conditioning regimen was applied including the fludarabine purine analogue (3 x 30 mg/m 2 ) and 200 cGy TBI. It was followed by transplantation of allogeneic cell concentrate containing 2.5 x10 6 /kg CD34+ and 4.0 x10 6 /kg CD34+ blood stem cells of partially compatible family donors (a sister and a son), which were tolerable for the patients without complications. Cyclosporine and mycophelonate mofetile were applied as post-transplantation treatment. Active antibiotic, antiviral, symptomatic and substituting therapy, as well as GvHD prophylaxis was applied for both patients. Good clinical tolerance was recorded for the applied low dose conditioning regimen. The patients were discharged within 30 days in good general condition and stable draft action, with

  14. Levan And Levansucrase-A Mini Review

    Directory of Open Access Journals (Sweden)

    Bruna Caroline Marques Goncalves

    2015-05-01

    Full Text Available Abstract Levansucrase is a fructosyltranferase that synthesizes levan and present great biotechnological interest. Its being widely used in therapeutic food cosmetic and pharmaceutical industries. Levansucrase is produced by many microorganisms such as the Bacillus subtilis Natto using the sucrose fermentation. In this mini-review we described some properties and functions of this important group of enzymes and the recent technologies used in the production and purification of levansucrase and levan.

  15. Mini-Cog and Mini-Mental State Examination: agreement in a cross-sectional study with an elderly sample.

    Science.gov (United States)

    Costa, Diogo; Severo, Milton; Fraga, Sílvia; Barros, Henrique

    2012-01-01

    We aimed to compare the Mini-Mental State Examination (MMSE) with the Mini-Cog, measuring agreement in participants' classification, using a general population sample. Cross-sectional evaluation of 609 community dwellers aged ≥60 years was performed by trained interviewers. Cohen's kappa and 95% confidence intervals (CI) were calculated to assess overall agreement, and Cronbach alphas computed to assess reliability. Two-parameter Item Response Theory models (difficulty and discrimination parameters) were used to assess discrimination. Considering MMSE cut-point for scores Mini-Cog's cut-point score Mini-Cog Mini-Cog Mini-Cog's alpha was 0.2776. Co-calibration according to inherent ability is graphically presented. Agreement between scales seems fragile in our sample. The discriminative and reliability analysis suggests a better performance for subsets of the MMSE compared with the Mini-Cog. Usefulness of calibrated scores is discussed. Copyright © 2012 S. Karger AG, Basel.

  16. RESPON LINGKUNGAN BELANJA SEBAGAI STIMULUS PEMBELIAN TIDAK BERENCANA PADA MINI MARKET MAMI MART PAINAN

    Directory of Open Access Journals (Sweden)

    Mareta Kemala Sari

    2014-10-01

    Full Text Available Research planning not purchase the mami mini market mart visits from customer response to environmental spending as a stimulus, a customer case study on mini market mart mom Painan. Research using response variables shopping environment consisting of Pleasure, Arousal, Dominance.as mediator variable, hedonic shopping value, utilitarian shopping value, resources expenditure on the purchase was not planned (Impulse Buying. Data were collected using questionnaires distributed during the 2 weeks to the respondents who never shop at mini market. The study population is that they all are a mini market mami mart customers aged 18-55 years and have never shopped with a minimum of 2 times the transaction, the methods used by the descriptive analysis, and processing research model with smartPLS program. Mengunggapkan research results that the response variable dominance shopping environment positive effect on resources expenditure. Shopping environment arousal response variable positive effect on resources expenditure. Also revealed that spending resources poengalaman variable expenditure not a mediator between the response variable shopping environment and other variables shopping experience, as well as the negative effect on the purchase was not planned. But the expenditure of resources affect the shopping experience more variables such as the hedonic shopping value, utilitarian shopping value, resources expenditure

  17. Assessment of functioning in patients with schizophrenia and schizoaffective disorder with the Mini-ICF-APP: a validation study in Italy.

    Science.gov (United States)

    Pinna, Federica; Fiorillo, Andrea; Tusconi, Massimo; Guiso, Beatrice; Carpiniello, Bernardo

    2015-01-01

    The aim of the study was to evaluate validity of the Italian Mini-ICF-APP (Mini-ICF Rating for Limitations of Activities and Participation in Psychological Disorders) in schizophrenia and related disorders. 74 outpatients affected by schizophrenia or schizoaffective disorders attending a University-based community mental health centre were recruited to the study. All participants underwent comprehensive evaluation using standardized instruments to assess clinical, neurocognitive and functional status. Concurrent validity of Mini-ICF-APP was evaluated and compared to severity scores obtained using the Clinical Global Impression-Schizophrenia scale (CGI-SCH), Positive and Negative Syndrome scale (PANSS), Mini Mental State Examination test (MMSE), Brief Assessment of Cognition in Schizophrenia scale (BACS) and Personal and Social Performance scale (PSP). Construct validity was evaluated by comparing scores obtained at Mini-ICF-APP by remitted versus non-remitted patients, and by recovered versus unrecovered patients. Discriminant validity was evaluated comparing scores on Mini-ICF-APP and Subjective Well-being (SWN) scale. the total score and 12 out of the 13 Mini-ICF-APP items correlated significantly with total score at PSP; Mini-ICF-App total score was moreover significantly correlated with total scores at CGI-SCH, PANSS, MMSE, as well as with several BACS items. Total scores obtained at Mini-ICF-APP were significantly higher among remitted and recovered patients. No relevant correlations were found between scores of Mini-ICF-APP and SWN scales. The total score and 12 out of the 13 Mini-ICF-APP items correlated significantly with total score at PSP; Mini-ICF-App total score was moreover significantly correlated with total scores at CGI-SCH, PANSS, MMSE, as well as with several BACS items. Total scores obtained at Mini-ICF-APP were significantly higher among remitted and recovered patients. No relevant correlations were found between scores of Mini-ICF-APP and SWN

  18. PV-hybrid and mini-grid

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    Within the 5th European PV-hybrid and mini-grid conference 29th and 30th April, 2010 in Tarragona (Spain) the following lectures were held: (1) Overview of IEA PVPS Task 11 PV-hybrid systems within mini grids; (2) Photovoltaic revolution for deployment in developing countries; (3) Legal and financial conditions for the sustainable operation of mini-grids; (4) EU instruments to promote renewable energies in developing countries; (5) PV hybridization of diesel electricity generators: Conditions of profitability and examples in differential power and storage size ranges; (6) Education suit of designing PV hybrid systems; (7) Sustainable renewable energy projects for intelligent rural electrification in Laos, Cambodia and Vietnam; (8) Techno-economic feasibility of energy supply of remote villages in Palestine by PV systems, diesel generators and electric grid (Case studies: Emnazeil and Atouf villages); (9) Technical, economical and sustainability considerations of a solar PV mini grid as a tool for rural electrification in Uganda; (10) Can we rate inverters for rural electrification on the basis of energy efficiency?; (11) Test procedures for MPPT charge controllers characterization; (12) Energy storage for mini-grid stabilization; (13) Redox flow batteries - Already an alternative storage solution for hybrid PV mini-grids?; (14) Control methods for PV hybrid mini-grids; (15) Partial AC-coupling in mini-grids; (15) Normative issues of small wind turbines in PV hybrid systems; (16) Communication solutions for PV hybrid systems; (17) Towards flexible control and communication of mini-grids; (18) PV/methanol fuel cell hybrid system for powering a highway security variable message board; (19) Polygeneration smartgrids: A solution for the supply of electricity, potable water and hydrogen as fuel for transportation in remote Areas; (20) Implementation of the Bronsbergen micro grid using FACDS; (21) A revisited approach for the design of PV wind hybrid systems; (22

  19. Maximum atmosphere at the Mini Atomiades

    CERN Multimedia

    Rachel Bray, Atomiades organizer team

    2016-01-01

    CERN Clubs Coordination Committee and CERN Staff Association host the ASCERI Mini Atomiades June 2016.   The CERN team won the tennis tournament for the Mini Atomiades 2016. (Photo: Erwin Van Hove) Over 180 participants from 10 different European Scientific Research Institutes came together on the first weekend of June in Divonne-les-Bains to take part in the ASCERI Sport & Science Mini Atomiades. Sports men and women from Belgium, Germany, France, Hungary, Russia and Switzerland battled it out in four different tournaments for medals, cups and, above all, lots of fun. The four disciplines included football, golf, tennis and a 10km race. CERN was victorious in tennis, golf and the men's and women's 10km, and despite the CERN football team putting up an excellent fight against some very strong teams they came almost last (we cannot win everything, can we?). But CERN were the clear winners for team spirit, community and camaraderie, as confirmed by all the comp...

  20. Psychometric Evaluation of the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID).

    Science.gov (United States)

    Duncan, Laura; Georgiades, Kathy; Wang, Li; Van Lieshout, Ryan J; MacMillan, Harriet L; Ferro, Mark A; Lipman, Ellen L; Szatmari, Peter; Bennett, Kathryn; Kata, Anna; Janus, Magdalena; Boyle, Michael H

    2017-12-04

    The goals of the study were to examine test-retest reliability, informant agreement and convergent and discriminant validity of nine DSM-IV-TR psychiatric disorders classified by parent and youth versions of the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID). Using samples drawn from the general population and child mental health outpatient clinics, 283 youth aged 9 to 18 years and their parents separately completed the MINI-KID with trained lay interviewers on two occasions 7 to 14 days apart. Test-retest reliability estimates based on kappa (κ) went from 0.33 to 0.79 across disorders, samples and informants. Parent-youth agreement on disorders was low (average κ = 0.20). Confirmatory factor analysis provided evidence supporting convergent and discriminant validity. The MINI-KID disorder classifications yielded estimates of test-retest reliability and validity comparable to other standardized diagnostic interviews in both general population and clinic samples. These findings, in addition to the brevity and low administration cost, make the MINI-KID a good candidate for use in epidemiological research and clinical practice. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  1. Caisson disease of bone: a study of the Göttingen mini-pig as an animal model.

    Science.gov (United States)

    Gregg, P J; Walder, D N; Rannie, I

    1980-02-01

    Investigation of the exact aetiology, early diagnosis and prevention of caisson disease of bone has been hindered by the inability to produce, by the use of realistic compression/decompression exposures, truly comparable lesions in animals. Four Gottingen mini-pigs were subjected to repeated exposures to pressures of 27 p.s.i.g. for 6 h over a period of 9 months and decompressed according to standard tables. Two mini-pigs acted as controls. In one animal radiological changes were recognised in the left lower femoral shaft 19 weeks after the exposures were started and subsequent examination of that bone confirmed the presence, at that site, of a lesion which macroscopically and microscopically resembled, in every way, the appearances of those seen in the shafts of long bones in man. It is concluded therefore that, properly used, the mini-pig may be a suitable animal model for the study of this condition in man.

  2. Re-examining the factor structure and psychometric properties of the Mini-Mental Adjustment to Cancer Scale in a sample of 364 Chinese cancer patients.

    Science.gov (United States)

    Fong, Ted C T; Ho, Rainbow T H

    2015-02-01

    The Mini-Mental Adjustment to Cancer Scale (Mini-MAC) is widely used to evaluate cancer patients' psychological responses. Validation studies of the scale have shown methodological shortcomings and inconsistency in the factor solutions. The aim of this study was to examine the factor structure and psychometric properties of the Mini-MAC. A large sample of 364 Chinese patients with breast or colorectal cancer completed the Mini-MAC and psychosocial measures (general health, perceived stress, anxiety, and depression). Exploratory factor analyses examined the relative fit of two- to six-factor models using robust weighted least square estimation and oblique target rotation. Convergent validity was evaluated via correlations between the Mini-MAC factor scores and the psychosocial outcomes. The five-factor model showed the best model fit and largely replicated the original Mini-MAC's helpless/hopeless (HH), anxious preoccupation (AP), fighting spirit (FS), fatalism (FA), and cognitive avoidance (CA) subscales. The five factors had acceptable reliability (Cronbach's α = 0.67-0.88) and 4-month test-retest reliability (r = 0.45-0.64). HH, AP, and CA were positively associated with the psychosocial outcomes (r = 0.19-0.60). Modest and negative correlations were found between the psychosocial outcomes and FS and FA. The results support the Mini-MAC's original five-factor structure with satisfactory reliability and convergent validity. The results demonstrate that the Mini-MAC is a valid measure for assessing psychological responses in cancer patients.

  3. Designing a mini subcritical nuclear reactor

    International Nuclear Information System (INIS)

    Escobedo G, C. R.; Vega C, H. R.; Davila H, V. M.

    2015-10-01

    In this work the design of a mini subcritical nuclear reactor formed by means of light water moderator, uranium as fuel, and isotopic neutron source of 239 PuBe was carried out. The design was done by Monte Carlo methods with the code MCNP5 in which uranium was modeled in an array of concentric holes cylinders of 8.5, 14.5, 20.5, 26.5, 32.5 cm of internal radius and 3 cm of thickness, 36 cm of height. Different models were made from a single fuel cylinder (natural uranium) to five. The neutron source of 239 PuBe was situated in the center of the mini reactor; in each arrangement was used water as moderator. Cross sections libraries Endf/Vi were used and the number of stories was large enough to ensure less uncertainty than 3%. For each case the effective multiplication factor k e -f f , the amplification factor and the power was calculated. Outside the mini reactor the ambient dose equivalent H (10) was calculated for different cases. The value of k eff , the amplification factor and power are directly related to the number of cylinders of uranium as fuel. Although the average energy of the neutrons 239 PuBe is between 4.5 and 5 MeV in the case of the mini reactor for a cylinder, in the neutron spectrum the presence of thermal neutrons does not exist, so that produced fissions are generated with fast neutrons, and in designs of two and three rings the neutron spectra shows the presence of thermal neutrons, however the fissions are being generated with fast neutrons. Finally in the four and five cases the amount of moderator is enough to thermalized the neutrons and thereby produce the fission. The maximum value for k eff was 0.82; this value is very close to the assembly of Universidad Autonoma de Zacatecas generating a k eff of 0.86. According to the safety and radiation protection standards for the design of mini reactor of one, two and three cylinders they comply with the established safety, while designs of four and five cylinders not met. (Author)

  4. The 'mini brain' appearance of plasmacytoma in the appendicular skeleton

    Energy Technology Data Exchange (ETDEWEB)

    Subhas, N.; Sundaram, M. [Cleveland Clinic, Department of Diagnostic Radiology, Cleveland, OH (United States); Bauer, T.W. [Cleveland Clinic, Department of Anatomic Pathology, Cleveland, OH (United States); Joyce, M.J. [Cleveland Clinic, Department of Orthopaedic Surgery, Cleveland, OH (United States)

    2008-08-15

    We report on the case of a 70-year-old woman presenting with right hip pain. Radiographs of the right hip demonstrated a well-defined large lytic lesion in the proximal right femur, with prominent trabeculae situated peripherally and extending into the lesion in a 'spoke-wheel' pattern. Magnetic resonance imaging (MRI) demonstrated solid enhancing marrow-replacing lesion, with intervening linear nonenhancing areas of low T2 signal intensity. The MRI appearance resembled that of a small brain or 'mini brain'. Biopsy specimen demonstrated predominantly mature plasma cells, with occasional admixed immature forms. A diagnosis of plasmacytosis, consistent with myeloma, was made. This case illustrates a rare but seemingly characteristic 'mini brain' appearance of plasmacytoma, which, to date, has only been reported in the spine and has not been observed in other bony lesions. (orig.)

  5. Noninvasive prenatal diagnosis. Use of density gradient centrifugation, magnetically activated cell sorting and in situ hybridization

    DEFF Research Database (Denmark)

    Campagnoli, C; Multhaupt, H A; Ludomirski, A

    1997-01-01

    OBJECTIVE: To develop a noninvasive method suitable for clinical prenatal diagnosis. STUDY DESIGN: Fetal nucleated erythrocytes were separated from peripheral blood of 17 healthy pregnant women using small magnetically activated cell sorting columns (MiniMACS) following density gradient centrifug...

  6. Magnet-Sleeve-Sealed Mini Trochoidal-Gear Pump Prototype with Polymer Composite Gear

    Directory of Open Access Journals (Sweden)

    Pedro Javier Gamez-Montero

    2017-09-01

    Full Text Available The trochoidal-gear technology has been growing in groundbreaking fields. Forthcoming applications are demanding to this technology a step forward in the conceiving stage of positive displacement machines. The compendium of the qualities and the inherent characteristics of trochoidal-gear technology, especially towards the gerotor pump, together with scale/size factor and magnetic-driven transmission has led to the idea of a magnet-sleeve-sealed variable flow mini trochoidal-gear pump. From its original concept, to the last phase of the design development, the proof of concept, this new product will intend to overcome problems such as noise, vibration, maintenance, materials, and dimensions. The paper aims to show the technological path followed from the concept, design, and model, to the manufacture of the first prototype, where the theoretical and numerical approaches are not always directly reflected in the prototype performance results. Early in the design process, from a standard-commercial sintered metal mini trochoidal-gear unit, fundamental characteristics and dimensional limitations have been evaluated becoming the strategic parameters that led to its configuration. The main technical challenge to confront is being sealed with non-exterior driveshaft, ensuring that the whole interior is filled and wetted with working fluid and helping the hydrodynamic film formation, the pumping effect, and the heat dissipation. Subsequently, the mini pump architecture, embodiment, methodology, materials, and manufacture are presented. The trend of applications of polymer composite materials and their benefits wanted to be examined with this new mini pump prototype, and a pure polyoxymethylene mini trochoidal-gear set has been designed and manufactured. Finally, both the sintered and the polymer trochoidal-gear units have been experimentally tested in an in-house full-instrumented mini test bench. Although the main goal of the presented work is the

  7. Mini-stop bands in single heterojunction photonic crystal waveguides

    KAUST Repository

    Shahid, N.; Amin, M.; Naureen, S.; Anand, S.

    2013-01-01

    Spectral characteristics of mini-stop bands (MSB) in line-defect photonic crystal (PhC) waveguides and in heterostructure PhC waveguides having one abrupt interface are investigated. Tunability of the MSB position by air-fill factor heterostructure PhC waveguides is utilized to demonstrate different filter functions, at optical communication wavelengths, ranging from resonance-like to wide band pass filters with high transmission. The narrowest filter realized has a resonance-like transmission peak with a full width at half maximum of 3.4 nm. These devices could be attractive for coarse wavelength selection (pass and drop) and for sensing applications. 2013 Copyright 2013 Author(s). This article is distributed under a Creative Commons Attribution 3.0 Unported License.

  8. Mini-Exame do Estado Mental: características psicométricas em idosos ambulatoriais Mini-Mental State Examination: psychometric characteristics in elderly outpatients

    Directory of Open Access Journals (Sweden)

    Roberto A Lourenço

    2006-08-01

    Full Text Available OBJETIVO: Avaliar as características de medida do Mini-Exame do Estado Mental em idosos atendidos em um ambulatório geral. MÉTODOS: O total de 303 indivíduos (>65 anos foi submetido à avaliação geriátrica com vários instrumentos, inclusive o Mini-Exame do Estado Mental. Foram calculadas a sensibilidade, a especificidade, os valores preditivos positivo e negativo e a curva ROC. RESULTADOS: A sensibilidade, a especificidade, os valores preditivos positivo e negativo e a área sob a curva ROC foram 80,8%, 65,3%, 44,7%, 90,7% e 0,807, respectivamente (ponto de corte 23/24. O melhor ponto de corte para indivíduos analfabetos foi 18/19 (sensibilidade =73,5%; especificidade =73,9%, e para aqueles com instrução escolar foi 24/25 (sensibilidade =75%; especificidade =69,7%. CONCLUSÕES: Para o rastreamento cognitivo de idosos atendidos em ambulatórios gerais pelo Mini-Exame do Estado Mental, a escolaridade deverá ser considerada para a adoção do ponto de corte mais adequado.OBJECTIVE: To assess the psychometric characteristics of the Mini-Mental State Examination in elderly outpatients who seek primary health care. METHODS: A total of 303 subjects (>65 years underwent comprehensive geriatric assessment with functional tools, including Mini-Mental State Examination. Sensitivity, specificity, positive predictive value, negative predictive value, and ROC curve were calculated. RESULTS: Sensitivity, specificity, positive and negative predictive values, and area under ROC curve were 80.8%, 65.3%, 44.7%, 90.7% and 0.807 respectively (cutoff point =23/24. The best cutoff point for illiterate was 18/19 (sensitivity =73.5%; specificity =73.9%; and for literate was 24/25 (sensitivity =75%; specificity =69.7%. CONCLUSIONS: While screening elderly outpatients for dementia, schooling must be considered in the choice of the best cutoff point in the Mini-Mental State Examination.

  9. The Saint Louis University Mental Status Examination Is Better than the Mini-Mental State Examination to Determine the Cognitive Impairment in Turkish Elderly People.

    Science.gov (United States)

    Kaya, Derya; Isik, Ahmet Turan; Usarel, Cansu; Soysal, Pinar; Ellidokuz, Hulya; Grossberg, George T

    2016-04-01

    Presence of detailed screening instruments to detect cognitive impairment in the older adults' culture and language is very essential. The Saint Louis University Mental Status Examination (SLUMS) is one of cognitive screening scales used. The aim of the study was to establish the validity and reliability of the Turkish version of SLUMS (SLUMS-T). Two hundred seventy-four participants aged 60 years and older admitted to our geriatric clinic were screened for cognitive impairment using SLUMS-T and Mini-Mental State Examination. Internal consistency was analyzed with Cronbach α test. Area under curves of receiver operating characteristic analyses were used to test the predictive accuracy of the SLUMS-T for detecting amnestic mild cognitive impairment (aMCI) and Alzheimer disease (AD) to set an appropriate cut-off point. The SLUMS-T scores were positively correlated with the Mini-Mental State Examination scores of the patients with aMCI and patients with AD and controls (r = 0.687, P < .001; r = 0.880, P < .001; respectively). Internal consistency of the SLUMS-T was Cronbach α = 0.85. It was found that SLUMS-T with a cut-off point of 23 had a sensitivity of 66.6% and a specificity of 72.3% for the diagnosis of aMCI, and with a cut-off point of 20 had a sensitivity of 83.8% and a specificity of 87.3% for the diagnosis of AD. SLUMS-T was demonstrated to have sufficient validity and reliability to evaluate cognitive impairment including MCI among Turkish elderly people. Copyright © 2016 AMDA – The Society for Post-Acute and Long-Term Care Medicine. All rights reserved.

  10. Prospects for Antineutrino Running at MiniBooNE

    OpenAIRE

    Wascko, M. O.

    2006-01-01

    MiniBooNE began running in antineutrino mode on 19 January, 2006. We describe the sensitivity of MiniBooNE to LSND-like nuebar oscillations and outline a program of antineutrino cross-section measurements necessary for the next generation of neutrino oscillation experiments. We describe three independent methods of constraining wrong-sign (neutrino) backgrounds in an antineutrino beam, and their application to the MiniBooNE antineutrino analyses.

  11. Imaging technique for the complete edentulous patient treated conventionally or with mini implant overdenture

    Science.gov (United States)

    Meleşcanu Imre, M; Preoteasa, E; Țâncu, AM; Preoteasa, CT

    2013-01-01

    Rationale. The imaging methods are more and more used in the clinical process of modern dentistry. Once the implant based treatment alternatives are nowadays seen as being the standard of care in edentulous patients, these techniques must be integrated in the complete denture treatment. Aim. The study presents some evaluation techniques for the edentulous patient treated by conventional dentures or mini dental implants (mini SKY Bredent) overdentures, using the profile teleradiography. These offer data useful for an optimal positioning of the artificial teeth and the mini dental implants, favoring to obtain an esthetic and functional treatment outcome. We proposed also a method to conceive a simple surgical guide that allows the prosthetically driven implants placement. Material and method. Clinical case reports were made, highlighting the importance of cephalometric evaluation on lateral teleradiographs in complete edentulous patients. A clinical case that gradually reports the surgical guide preparation (Bredent silicon radio opaque), in order to place the mini dental implants in the best prosthetic and anatomic conditions, was presented. Conclusions. The profile teleradiograph is a useful tool for the practitioner. It allows establishing the optimal site for implant placement, in a good relation with the overdenture. The conventional denture can be easily and relatively costless transformed in a surgical guide used during implant placement. PMID:23599828

  12. The ASTRI Mini-Array Science Case

    Science.gov (United States)

    Vercellone, Stefano; Catalano, O.; Maccarone, M.; Stamerra, A.; Di Pierro, F.; Vallania, P.; Canestrari, R.; Bonnoli, G.; Pareschi, G.; Tosti, G.; Caraveo, P.; ASTRI Collaboration

    2013-04-01

    ASTRI is a flagship project of the Italian Ministry of Education, University and Research. Within this framework, INAF is currently developing an end-to-end prototype of the CTA small-size telescope in a dual-mirror configuration (SST-2M) to be tested under field conditions, and scheduled to start data acquisition in 2014. A remarkable improvement in terms of performance could come from the operation, in 2016, of a SST-2M mini-array, composed by a few SST-2M telescopes and to be placed at final CTA Southern Site. The SST mini-array will be able to study in great detail relatively bright sources (a few x10E-12 erg/cm2/s at 10 TeV) with an angular resolution of a few arcmin and an energy resolution of about 10 - 15%. Moreover, thanks to the array approach, it will be possible to verify the wide FoV performance to detect very high energy showers with the core located at a distance up to 500 m, to compare the mini-array performance with the Monte Carlo expectations by means of deep observations of few selected targets, and to perform the first CTA science, with its first solid detections during the first year of operation. Prominent sources such as extreme blazars (1ES 0229+200), nearby well-known BL Lac objects (MKN 501) and radio-galaxies, galactic pulsar wind nebulae (Crab Nebula, Vela-X), supernovae remnants (Vela-junior, RX J1713.7-3946) and microquasars (LS 5039), as well as the Galactic Center can be observed in a previously unexplored energy range, in order to investigate the electron acceleration and cooling, relativistic and non relativistic shocks, the search for cosmic-ray (CR) Pevatrons, the study of the CR propagation, and the impact of the extragalactic background light on the spectra of the sources.

  13. Mini-marathon groups: psychological "first aid" following disasters.

    Science.gov (United States)

    Terr, L C

    1992-01-01

    Large group counseling sessions for soldiers following battle have been commonly used since World War II. The author conceptualizes and demonstrates how these mini-marathon sessions can be adapted to support all ages and types of civilians involved in disasters. Mini-marathons take about 3 hours and are divided into three sections: story sharing, symptom sharing, and suggestions for self-help, including sharing tales of heroism and survival. After an initial mini-marathon session, a second session may be held emphasizing creativity. The author also describes how mini-marathons can be adapted for therapists who will lead their own sessions.

  14. Mini-open transforaminal lumbar interbody fusion.

    Science.gov (United States)

    Tangviriyapaiboon, Teera

    2008-09-01

    To demonstrate the surgical technique and advantages of the mini-open transforaminal approach for lumbar interbody fusion (TLIF) combined with transpedicular screw fixation. Clinical and radiographic results were assessed to determine the clinical outcomes in twelve consecutive patients selected for minimally invasive access (mini-open technique) for TLIF in Prasat Neurological Institute. A retrospective analysis was performed on 12 patients (age range, 38-74 yr; mean, 54. 8 yr) who underwent mini-open transforaminal approach for lumbar interbody fusion (TLIF) combined with transpedicular screw fixation between September 2006 and June 2008. The titanium pedicle screws were introduced bilaterally through the 3.5 cm length, skin incisions with Spine Classics MLD- system retractor, autologous bone graft were inserted to perform TLIF in all patients. Eight patients were augmented anterior column support with titanium interbody cage, unilateral cage insertion in four patients and the others were inserted bilaterally interbody cages. Six patients presented with low back pain and associated radiculopathy, and six presented with low back pain only. Transforaminal lumbar interbody fusion was performed at L3-L4 in two patients, L4-L5 in four patients, L5-S1 in five patients, and two levels fusion in one patient. All patients were able to ambulate after spinal fusion. The patients were able to walk within 1.4 days (range 1-2 days). The hospital stay averaged 4.4 days (range 3-7 days). Periodic follow-up took place 1 to 21 months after surgery (mean, 7.4 months). The radiological fusion was archived in all nine patients who were operated on more than two months age. The other three patients who had been follow-up less than two months were probably fusion on the 1-month followed-up radiological examination. The use of mini-open technique for pedicle screw instrumentation with spinal fusion procedure provides excellent clinical results and may be an operation of choice for

  15. Mini-projects in Chemical Engineering Laboratory

    Directory of Open Access Journals (Sweden)

    Angeles Cancela

    2013-03-01

    Full Text Available Chemical engineering laboratory practices based in mini-projects were design and applied the students of forestry engineering in chemical subject. This way of practice reveals a more cooperative learning and a different style of experimentation. The stated goal was to design practices that motivate students and to enable them to develop different skills, including cross teamwork and communication. This paper describes how these practices were developed and the advantages and disadvantages of using this methodology of teaching.

  16. Review of mini-clinical evaluation exercise (mini-CEX in a psychiatry clerkship

    Directory of Open Access Journals (Sweden)

    Meresh E

    2018-04-01

    Full Text Available Edwin Meresh,1 David Daniels,2 Aparna Sharma,1 Murali Rao,1 Kaushal Mehta,3 David Schilling1 1Department of Psychiatry and Behavioral Neurosciences, Stritch School of Medicine, Loyola University Medical Center, Maywood, IL, USA; 2Department of Psychiatry, Medstar Georgetown University Hospital, Washington, DC, USA; 3School of Public Health, Stritch School of Medicine, Loyola University Medical Center, Maywood, IL USA Background: Direct observation of medical students with actual patients is important for the assessment of clinical skills including interviewing and counseling skills. This article describes medical students’ experience of mini-clinical evaluation exercise (mini-CEX during their clerkship in consultation psychiatry. Materials and methods: In our center during inpatient consultation psychiatry clerkship, all rotating students are expected to complete one mini-CEX assessment as part of their clinical training. We conducted retrospective analysis of mini-CEX ratings completed from 2013 to 2016. All evaluations took place at inpatient medical setting in patients admitted with medical conditions and psychiatric comorbidities. Results: A total of 113 evaluations were reviewed. The time examiner observed the interaction of a student with the patient was 14.24 minutes (mean, and the time spent in providing feedback to the student was 9.71 minutes. Complexity of problem was rated as low in 0.88% (n=1, moderate in 50.44% (n=57, and high in 48.67% (n=55. Highest ratings were for professionalism, similar to previous reports. Total score calculated by examiner showed no difference by the complexity of the patient; however, we observed a trend in higher counseling score for the high complexity group. Conclusion: Mini-CEX assessment during busy clerkship is feasible with good outcomes. Direct observation of medical trainees with actual patients is important for the assessment of performance-based clinical skills. Hospital psychiatry rotation

  17. La importancia del diagnóstico temprano en la supervivencia de los pacientes HIV positivos The importance of early diagnosis for the survival of HIV positive patients

    Directory of Open Access Journals (Sweden)

    Darío A. Dilernia

    2010-10-01

    Full Text Available En la Argentina, el diagnóstico del HIV se realiza por solicitud voluntaria de los individuos o a través de la detección de sintomatología asociada a la infección. Sin embargo, debido a la elevada proporción de sujetos portadores que desconocen su estado serológico son necesarias nuevas estrategias. En el presente artículo mostramos cómo un modelo matemático predice el impacto de la expansión de la prueba diagnóstica del HIV en la Argentina. El modelo se basa en matrices de Markov y utiliza probabilidades de transición dependientes de parámetros obtenidos de estudios de cohortes nacionales e internacionales. Las predicciones incluyen tiempo en estadios clínicos y tratamiento, conteo de CD4, carga viral, estadío de infección, edad, tasas de mortalidad y proporción de infección desconocida a nivel poblacional. Las simulaciones se desarrollaron para la situación actual y para un escenario hipotético con diagnóstico más temprano. Mostramos predicciones que sugieren que el diagnóstico realizado antes de la progresión a sida incrementaría la expectativa de vida en unos 10.7 años. También, mostramos cómo la reducción del tiempo al diagnóstico hasta 5 años o menos desde la infección reduciría la tasa de mortalidad en el primer año de HAART de 7.6% a 2.1%, la proporción de infección no reconocida de 43.2% a 23.8% y la proporción de individuos con infección desconocida y que requieren tratamiento de 12% a 0.2%. Basados en estas predicciones resaltamos la importancia de implementar políticas de salud destinadas a detectar la infección por HIV en estadios tempranos en la Argentina.In Argentina, HIV diagnosis is reached by voluntary testing or symptom-based case findings. However, because of the high proportion of infected individuals unaware of their serologic status new strategies are required. In this article we show how a mathematic model predicts the impact of expanding HIV testing in Argentina. The model is

  18. MSH6 and PMS2 mutation positive Australian Lynch syndrome families: novel mutations, cancer risk and age of diagnosis of colorectal cancer.

    Science.gov (United States)

    Talseth-Palmer, Bente A; McPhillips, Mary; Groombridge, Claire; Spigelman, Allan; Scott, Rodney J

    2010-05-21

    Approximately 10% of Lynch syndrome families have a mutation in MSH6 and fewer families have a mutation in PMS2. It is assumed that the cancer incidence is the same in families with mutations in MSH6 as in families with mutations in MLH1/MSH2 but that the disease tends to occur later in life, little is known about families with PMS2 mutations. This study reports on our findings on mutation type, cancer risk and age of diagnosis in MSH6 and PMS2 families. A total of 78 participants (from 29 families) with a mutation in MSH6 and 7 participants (from 6 families) with a mutation in PMS2 were included in the current study. A database of de-identified patient information was analysed to extract all relevant information such as mutation type, cancer incidence, age of diagnosis and cancer type in this Lynch syndrome cohort. Cumulative lifetime risk was calculated utilising Kaplan-Meier survival analysis. MSH6 and PMS2 mutations represent 10.3% and 1.9%, respectively, of the pathogenic mutations in our Australian Lynch syndrome families. We identified 26 different MSH6 and 4 different PMS2 mutations in the 35 families studied. We report 15 novel MSH6 and 1 novel PMS2 mutations. The estimated cumulative risk of CRC at age 70 years was 61% (similar in males and females) and 65% for endometrial cancer in MSH6 mutation carriers. The risk of developing CRC is different between males and females at age 50 years, which is 34% for males and 21% for females. Novel MSH6 and PMS2 mutations are being reported and submitted to the current databases for identified Lynch syndrome mutations. Our data provides additional information to add to the genotype-phenotype spectrum for both MSH6 and PMS2 mutations.

  19. MSH6 and PMS2 mutation positive Australian Lynch syndrome families: novel mutations, cancer risk and age of diagnosis of colorectal cancer

    Directory of Open Access Journals (Sweden)

    Talseth-Palmer Bente A

    2010-05-01

    Full Text Available Abstract Background Approximately 10% of Lynch syndrome families have a mutation in MSH6 and fewer families have a mutation in PMS2. It is assumed that the cancer incidence is the same in families with mutations in MSH6 as in families with mutations in MLH1/MSH2 but that the disease tends to occur later in life, little is known about families with PMS2 mutations. This study reports on our findings on mutation type, cancer risk and age of diagnosis in MSH6 and PMS2 families. Methods A total of 78 participants (from 29 families with a mutation in MSH6 and 7 participants (from 6 families with a mutation in PMS2 were included in the current study. A database of de-identified patient information was analysed to extract all relevant information such as mutation type, cancer incidence, age of diagnosis and cancer type in this Lynch syndrome cohort. Cumulative lifetime risk was calculated utilising Kaplan-Meier survival analysis. Results MSH6 and PMS2 mutations represent 10.3% and 1.9%, respectively, of the pathogenic mutations in our Australian Lynch syndrome families. We identified 26 different MSH6 and 4 different PMS2 mutations in the 35 families studied. We report 15 novel MSH6 and 1 novel PMS2 mutations. The estimated cumulative risk of CRC at age 70 years was 61% (similar in males and females and 65% for endometrial cancer in MSH6 mutation carriers. The risk of developing CRC is different between males and females at age 50 years, which is 34% for males and 21% for females. Conclusion Novel MSH6 and PMS2 mutations are being reported and submitted to the current databases for identified Lynch syndrome mutations. Our data provides additional information to add to the genotype-phenotype spectrum for both MSH6 and PMS2 mutations.

  20. A mini-exhibition with maximum content

    CERN Multimedia

    Laëtitia Pedroso

    2011-01-01

    The University of Budapest has been hosting a CERN mini-exhibition since 8 May. While smaller than the main travelling exhibition it has a number of major advantages: its compact design alleviates transport difficulties and makes it easier to find suitable venues in the Member States. Its content can be updated almost instantaneously and it will become even more interactive and high-tech as time goes by.   The exhibition on display in Budapest. The purpose of CERN's new mini-exhibition is to be more interactive and easier to install. Due to its size, the main travelling exhibition cannot be moved around quickly, which is why it stays in the same country for 4 to 6 months. But this means a long waiting list for the other Member States. To solve this problem, the Education Group has designed a new exhibition, which is smaller and thus easier to install. Smaller maybe, but no less rich in content, as the new exhibition conveys exactly the same messages as its larger counterpart. However, in the slimm...

  1. Premature pubarche before one year of age: distinguishing between mini-puberty variants and precocious puberty.

    Science.gov (United States)

    Bourayou, Rafik; Giabicani, Eloïse; Pouillot, Monique; Brailly-Tabard, Sylvie; Brauner, Raja

    2015-04-02

    The aim of this study was to facilitate the distinction between the benign "mini-puberty of early infancy" and precocious puberty (PP). We compared 59 patients (21 boys and 38 girls) seen for pubic hair development before one year of age diagnosed as mini-puberty to 13 patients (2 boys) in whom pubertal development before one year revealed a PP. The boys with mini-puberty presented with pubic hair development and prepubertal testicular volume, with low plasma testosterone concentrations. Their gonadotropin responses to gonadotropin releasing hormone (GnRH) test showed predominant luteinising hormone increase in 9/13. The girls presented with pubic hair development that was accompanied by breast development in 47% of cases, with low plasma estradiol concentrations. Their gonadotropin responses showed predominant follicle-stimulating hormone increase in the 17 evaluated. The patients with PP had organic central PP (5 hypothalamic hamartoma) or idiopathic central PP (n=6), or peripheral PP (one ovarian tumor and one congenital adrenal hyperplasia). The diagnosis was challenging only in 3 girls with idiopathic central PP presenting with prepubertal plasma estradiol concentrations and responses to GnRH test. The diagnosis of PP was easily determined based on the clinical presentation and the pubertal concentrations of testosterone in boys or of estradiol in girls, as was the diagnosis of central or peripheral origin of PP based on gonadotropin response to the GnRH test. Once PP is excluded, these patients need careful follow-up and physician consultation is needed if clinical pubertal signs progress.

  2. HIV diagnosis, linkage to HIV care, and HIV risk behaviors among newly diagnosed HIV-positive female sex workers in Kigali, Rwanda

    NARCIS (Netherlands)

    Braunstein, Sarah L.; Umulisa, Marie-Michèle; Veldhuijzen, Nienke J.; Kestelyn, Evelyne; Ingabire, Chantal M.; Nyinawabega, Jeanine; van de Wijgert, Janneke H. H. M.; Nash, Denis

    2011-01-01

    To evaluate linkage-to-care, sexual behavior change, and psychosocial experiences among newly HIV-diagnosed female sex workers (FSWs) in Rwanda. FSWs (n = 800) with unknown serostatus were screened for HIV during 2007/2008. Women testing HIV positive (n = 192) were referred to care and asked to

  3. Agreement between clinical and MINI diagnoses in outpatients with mood and anxiety disorders

    NARCIS (Netherlands)

    Verhoeven, F. E. A.; Swaab, L. S. M. A.; Carlier, I. V. E.; van Hemert, A. M.; Zitman, F. G.; Ruhé, H. G.; Schoevers, R. A.; Giltay, E. J.

    2017-01-01

    Background: Standardized Diagnostic Interviews (SDIs) such as the Mini International Neuropsychiatric Interview (MINI) are widely used to systematically screen for psychiatric disorders in research. To support generalizability of results to clinical practice, we assessed agreement between the MINI

  4. Surgical management of fractured orthodontic mini- implant- a case report.

    Science.gov (United States)

    Desai, Manthan; Jain, Anoop; Sumra, Nida

    2015-01-01

    The idea of absolute anchorage has always been an elusive goal for clinicians. Orthodontic mini-implants or temporary anchorage devices allow tooth movements previously thought to be impossible or difficult. Although extensive literature exists on use of temporary anchorage devices, their failures have been hardly focused upon, especially implant fracture. The following case report describes successful management of fractured orthodontic mini-implant.

  5. Paradigm shifts in orthodontic treatment with mini-implant anchorage

    Directory of Open Access Journals (Sweden)

    Johnny Joung-Lin Liaw

    2015-01-01

    Full Text Available After the applications of mini-implant anchorage, the envelope of orthodontic treatment was expanded and some treatment modes were changed because of more predictable tooth movement with empowered anchorage. The author tried to share his experience of TADs applications for clarifying the paradigm shifts of orthodontic treatment assisted with the mini-implant anchorage.

  6. Shear-wave elastography in the diagnosis of solid breast masses: what leads to false-negative or false-positive results?

    Science.gov (United States)

    Yoon, Jung Hyun; Jung, Hae Kyoung; Lee, Jong Tae; Ko, Kyung Hee

    2013-09-01

    To investigate the factors that have an effect on false-positive or false-negative shear-wave elastography (SWE) results in solid breast masses. From June to December 2012, 222 breast lesions of 199 consecutive women (mean age: 45.3 ± 10.1 years; range, 21 to 88 years) who had been scheduled for biopsy or surgical excision were included. Greyscale ultrasound and SWE were performed in all women before biopsy. Final ultrasound assessments and SWE parameters (pattern classification and maximum elasticity) were recorded and compared with histopathology results. Patient and lesion factors in the 'true' and 'false' groups were compared. Of the 222 masses, 175 (78.8 %) were benign, and 47 (21.2 %) were malignant. False-positive rates of benign masses were significantly higher than false-negative rates of malignancy in SWE patterns, 36.6 % to 6.4 % (P masses, factors showing significance among false SWE features were lesion size, breast thickness and lesion depth (all P breast masses had SWE images of good quality. False SWE features were more significantly seen in benign masses. Lesion size, breast thickness and lesion depth have significance in producing false results, and this needs consideration in SWE image acquisition. • Shear-wave elastography (SWE) is widely used during breast imaging • At SWE, false-positive rates were significantly higher than false-negative rates • Larger size, breast thickness, depth and fair quality influences false-positive SWE features • Smaller size, larger breast thickness and depth influences false-negative SWE features.

  7. De validiteit van de cognitieve screening-test en de 'mini-mental state examination' bij een groep oudere ziekenhuispatiënten

    NARCIS (Netherlands)

    Dautzenberg, P. L.; Schmand, B.; Vriens, M. T.; Deelman, B. G.; Hooijer, C.

    1991-01-01

    To study the validity of the cognitive screening test (CST) and of the mini-mental state examination (MMS). Prospective administration of both CST and MMS (in balanced order) by laymen as well as by experienced users, and retrospective comparison of the scores with the clinical diagnosis and with

  8. Psychometric Evaluation of a Dutch Version of the Mini PAS-ADD for Assessing Psychiatric Disorders in Adults with Different Levels of Intellectual Disability

    Science.gov (United States)

    Janssen, R.; Maes, B.

    2013-01-01

    Background: People with intellectual disabilities (ID) have an increased vulnerability to develop psychiatric problems. Moreover, the early recognition and the accurate diagnosis of psychiatric disorders in the population of persons with ID are challenging. Method: A Dutch version of the Mini PAS-ADD, which is a screening instrument for…

  9. A DNA mini-barcode for land plants.

    Science.gov (United States)

    Little, Damon P

    2014-05-01

    Small portions of the barcode region - mini-barcodes - may be used in place of full-length barcodes to overcome DNA degradation for samples with poor DNA preservation. 591,491,286 rbcL mini-barcode primer combinations were electronically evaluated for PCR universality, and two novel highly universal sets of priming sites were identified. Novel and published rbcL mini-barcode primers were evaluated for PCR amplification [determined with a validated electronic simulation (n = 2765) and empirically (n = 188)], Sanger sequence quality [determined empirically (n = 188)], and taxonomic discrimination [determined empirically (n = 30,472)]. PCR amplification for all mini-barcodes, as estimated by validated electronic simulation, was successful for 90.2-99.8% of species. Overall Sanger sequence quality for mini-barcodes was very low - the best mini-barcode tested produced sequences of adequate quality (B20 ≥ 0.5) for 74.5% of samples. The majority of mini-barcodes provide correct identifications of families in excess of 70.1% of the time. Discriminatory power noticeably decreased at lower taxonomic levels. At the species level, the discriminatory power of the best mini-barcode was less than 38.2%. For samples believed to contain DNA from only one species, an investigator should attempt to sequence, in decreasing order of utility and probability of success, mini-barcodes F (rbcL1/rbcLB), D (F52/R193) and K (F517/R604). For samples believed to contain DNA from more than one species, an investigator should amplify and sequence mini-barcode D (F52/R193). © 2013 John Wiley & Sons Ltd.

  10. Comparison of retrograde intrarenal surgery and mini-percutaneous nephrolithotomy in management of lower-pole renal stones with a diameter of smaller than 15 mm.

    Science.gov (United States)

    Kirac, Mustafa; Bozkurt, Ömer Faruk; Tunc, Lutfi; Guneri, Cagri; Unsal, Ali; Biri, Hasan

    2013-06-01

    The aim of this study was to compare the outcomes of retrograde intrarenal surgery (RIRS) and miniaturized percutaneous nephrolithotomy (mini-PNL) in management of lower-pole renal stones with a diameter smaller than 15 mm. Between December 2009 and July 2012, the patients with the diagnosis of lower-pole stones were evaluated by ultrasonography, intravenous pyelography and computed tomography. The records of 73 evaluable patients who underwent mini-PNL (n = 37) or RIRS (n = 36) for lower-pole (LP) stones with diameter smaller than 15 mm were reviewed retrospectively. Of the 73 patients, 37 underwent mini-PNL and 36 underwent RIRS. The stone-free rates were 89.1 and 88.8 % for mini-PNL and RIRS groups, respectively. The mean operation time was 53.7 ± 14.5 in the mini-PNL group but 66.4 ± 15.8 in the RIRS group (P = 0.01). The mean fluoroscopy times and hospitalization times were significantly higher in the mini-PNL group. There was no major complication in any patient. RIRS and mini-PNL are safe and effective methods for treatment of LP calculi with a diameter smaller than 15 mm. RIRS is a non-invasive and feasible treatment option, and has also short hospitalization time, low morbidity and complication rate. It may be an alternative of mini-PNL in the treatment LP calculi with smaller than 15 mm.

  11. Mini and Micro Propulsion for Medical Swimmers

    Directory of Open Access Journals (Sweden)

    JianFeng

    2014-02-01

    Full Text Available Mini and micro robots, which can swim in an underwater environment, have drawn widespread research interests because of their potential applicability to the medical or biological fields, including delivery and transportation of bio-materials and drugs, bio-sensing, and bio-surgery. This paper reviews the recent ideas and developments of these types of self-propelling devices, ranging from the millimeter scale down to the micro and even the nano scale. Specifically, this review article makes an emphasis on various propulsion principles, including methods of utilizing smart actuators, external magnetic/electric/acoustic fields, bacteria, chemical reactions, etc. In addition, we compare the propelling speed range, directional control schemes, and advantages of the above principles.

  12. Mini Review: Biomaterials for Enhancing Neuronal Repair

    Science.gov (United States)

    Cangellaris, Olivia V.; Gillette, Martha U.

    2018-04-01

    As they differentiate from neuroblasts, nascent neurons become highly polarized and elongate. Neurons extend and elaborate fine and fragile cellular extensions that form circuits enabling long-distance communication and signal integration within the body. While other organ systems are developing, projections of differentiating neurons find paths to distant targets. Subsequent post-developmental neuronal damage is catastrophic because the cues for reinnervation are no longer active. Advances in biomaterials are enabling fabrication of micro-environments that encourage neuronal regrowth and restoration of function by recreating these developmental cues. This mini-review considers new materials that employ topographical, chemical, electrical, and/or mechanical cues for use in neuronal repair. Manipulating and integrating these elements in different combinations will generate new technologies to enhance neural repair.

  13. Mini-mast CSI testbed user's guide

    Science.gov (United States)

    Tanner, Sharon E.; Pappa, Richard S.; Sulla, Jeffrey L.; Elliott, Kenny B.; Miserentino, Robert; Bailey, James P.; Cooper, Paul A.; Williams, Boyd L., Jr.; Bruner, Anne M.

    1992-01-01

    The Mini-Mast testbed is a 20 m generic truss highly representative of future deployable trusses for space applications. It is fully instrumented for system identification and active vibrations control experiments and is used as a ground testbed at NASA-Langley. The facility has actuators and feedback sensors linked via fiber optic cables to the Advanced Real Time Simulation (ARTS) system, where user defined control laws are incorporated into generic controls software. The object of the facility is to conduct comprehensive active vibration control experiments on a dynamically realistic large space structure. A primary goal is to understand the practical effects of simplifying theoretical assumptions. This User's Guide describes the hardware and its primary components, the dynamic characteristics of the test article, the control law implementation process, and the necessary safeguards employed to protect the test article. Suggestions for a strawman controls experiment are also included.

  14. Laser-Driven Mini-Thrusters

    International Nuclear Information System (INIS)

    Sterling, Enrique; Lin Jun; Sinko, John; Kodgis, Lisa; Porter, Simon; Pakhomov, Andrew V.; Larson, C. William; Mead, Franklin B. Jr.

    2006-01-01

    Laser-driven mini-thrusters were studied using Delrin registered and PVC (Delrin registered is a registered trademark of DuPont) as propellants. TEA CO2 laser (λ = 10.6 μm) was used as a driving laser. Coupling coefficients were deduced from two independent techniques: force-time curves measured with a piezoelectric sensor and ballistic pendulum. Time-resolved ICCD images of the expanding plasma and combustion products were analyzed in order to determine the main process that generates the thrust. The measurements were also performed in a nitrogen atmosphere in order to test the combustion effects on thrust. A pinhole transmission experiment was performed for the study of the cut-off time when the ablation/air breakdown plasma becomes opaque to the incoming laser pulse

  15. Laser-Driven Mini-Thrusters

    Science.gov (United States)

    Sterling, Enrique; Lin, Jun; Sinko, John; Kodgis, Lisa; Porter, Simon; Pakhomov, Andrew V.; Larson, C. William; Mead, Franklin B.

    2006-05-01

    Laser-driven mini-thrusters were studied using Delrin® and PVC (Delrin® is a registered trademark of DuPont) as propellants. TEA CO2 laser (λ = 10.6 μm) was used as a driving laser. Coupling coefficients were deduced from two independent techniques: force-time curves measured with a piezoelectric sensor and ballistic pendulum. Time-resolved ICCD images of the expanding plasma and combustion products were analyzed in order to determine the main process that generates the thrust. The measurements were also performed in a nitrogen atmosphere in order to test the combustion effects on thrust. A pinhole transmission experiment was performed for the study of the cut-off time when the ablation/air breakdown plasma becomes opaque to the incoming laser pulse.

  16. Characteristics of MINI ECR ion source

    Energy Technology Data Exchange (ETDEWEB)

    Saitoh, Yuichi; Yokota, Watalu [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    1997-03-01

    A very compact electron cyclotron resonance ion source (MINI ECR) was manufactured to extend available energy ranges of ion beams by applying multiply charged ions to electrostatic accelerators. The magnetic field to confine a plasma is formed only by small permanent magnets and the microwave power up to 15 W is generated by a compact transistor amplifier in order to install the ion source at a narrow high-voltage terminal where the electrical power feed is restricted. The magnet assembly is 12 cm in length and 11 cm in diameter, and forms a mirror field with the maximum strength of 0.55 T. The total power consumption of the source is below 160 W. The performance of the source was tested in a bench stand. The results of Ar, Xe, O, and N ion generation are reported in this paper. (author)

  17. A study of the flow boiling heat transfer in an annular heat exchanger with a mini gap

    Directory of Open Access Journals (Sweden)

    Musiał Tomasz

    2017-01-01

    Full Text Available In this paper the research on flow boiling heat transfer in an annular mini gap was discussed. A one- dimensional mathematical approach was proposed to describe stationary heat transfer in the gap. The mini gap 1 mm wide was created between a metal pipe with enhanced exterior surface and an external tempered glass pipe positioned along the same axis. The experimental test stand consists of several systems: the test loop in which distilled water circulates, the data and image acquisition system and the supply and control system. Known temperature distributions of the metal pipe with enhanced surface and of the working fluid helped to determine, from the Robin boundary condition, the local heat transfer coefficients at the fluid - heated surface contact. In the proposed mathematical model it is assumed that the cylindrical wall is a planar multilayer wall. The numerical results are presented on a chart as function of the heat transfer coefficient along the length of the mini gap.

  18. Relevance of the serial position effect in the differential diagnosis of mild cognitive impairment, Alzheimer-type dementia, and normal ageing.

    Science.gov (United States)

    Martín, M E; Sasson, Y; Crivelli, L; Roldán Gerschovich, E; Campos, J A; Calcagno, M L; Leiguarda, R; Sabe, L; Allegri, R F

    2013-05-01

    Serial position effects are observed when a person memorises a series of words exceeding his or her attention span. Cognitively normal individuals recall words at the beginning and end of the list more frequently than those in the middle, which reflects the way that short- and long-term episodic memory works. To study the serial position effect in patients with mild cognitive impairment (MCI) compared to subjects with Alzheimer-type dementia (AD) or normal ageing (NA). 30 AD, 25 MCI and 20 NA subjects underwent neurological and neuropsychological assessment. The Rey Auditory Verbal Learning Test (RAVLT) was used to study primacy, middle, and recency effects and delayed recall for each group. The general memory pattern of MCI subjects was very similar to that of AD subjects, and was characterised by reduced learning capacity, rapid forgetfulness and clear recency effect in learning. With regard to delayed recall, however, there were differences in performance; MCI subjects' ability to recall words at the beginning and middle of the list was similar to that of normal subjects, while their memory of words at the end of the list was poor, as in AD subjects. RAVLT is a tool permitting us to distinguish between MCI and NA subjects. The recency index for the delayed recall task is a valid indicator for distinguishing between MCI patients and patients with normal ageing. Copyright © 2011 Sociedad Española de Neurología. Published by Elsevier Espana. All rights reserved.

  19. Mini-grid Policy Tool-kit. Policy and business frameworks for successful mini-grid roll-outs

    International Nuclear Information System (INIS)

    Franz, Michael; Hayek, Niklas; Peterschmidt, Nico; Rohrer, Michael; Kondev, Bozhil; Adib, Rana; Cader, Catherina; Carter, Andrew; George, Peter; Gichungi, Henry; Hankins, Mark; Kappiah, Mahama; Mangwengwende, Simbarashe E.

    2014-01-01

    The Mini-grid Policy Tool-kit is for policy makers to navigate the mini-grid policy design process. It contains information on mini-grid operator models, the economics of mini-grids, and necessary policy and regulation that must be considered for successful implementation. The publication specifically focuses on Africa. Progress on extending the electricity grid in many countries has remained slow because of high costs of gird-extension and limited utility/state budgets for electrification. Mini-grids provide an affordable and cost-effective option to extend needed electricity services. Putting in place the right policy for min-grid deployment requires considerable effort but can yield significant improvement in electricity access rates as examples from Kenya, Senegal and Tanzania illustrate. The tool-kit is available in English, French and Portuguese

  20. Mini MAX-DOAS Measurements of Air Pollutants over China

    Science.gov (United States)

    Staadt, Steffen; Hao, Nan; Trautmann, Thomas

    2016-08-01

    This study continues the work of Clémer et al., (2010) and is aimed to improve trace gas retrievals with mini MAX-DOAS measurements in Nanjing. Based on that work, aerosol extinction vertical profiles are retrieved using the bePRO inversion algorithm developed by the Royal Belgian Institute for Space Aeronomy (BIRA- IASB). Afterwards, the tropospheric trace gas vertical profiles and vertical column densities (VCDs) are retrieved by applying the optimal estimation method to the O4 MAX-DOAS measurements. The Profiles for N O2 , S O2 , glyoxal, formaldehyde and nitrous acid are obtained with different results and different settings for the DOAS measurement. The AODs show small positive correlation against the AERONET values. For NO2, the retrieval shows reasonable concentrations in winter as opposed to summer and has small positive correlations with GOME-2 data. The SO2 VCDs are not correlated with the GOME-2 data, due to high uncertainties from MAX-DOAS and satellite retrievals, while the vertical mixing ratios (VMR) show good agreement with in-situ data (SORPES) at Nanjing. Nitrous acid shows a maximum in winter and a minimum in summer, while glyoxal has its maximum in August and September.

  1. Frontal EEG Asymmetry of Mood: A Mini-Review

    Directory of Open Access Journals (Sweden)

    Massimiliano Palmiero

    2017-11-01

    Full Text Available The present mini-review was aimed at exploring the frontal EEG asymmetry of mood. With respect to emotion, interpreted as a discrete affective process, mood is more controllable, more nebulous, and more related to mind/cognition; in addition, causes are less well-defined than those eliciting emotion. Therefore, firstly, the rational for the distinction between emotion and mood was provided. Then, the main frontal EEG asymmetry models were presented, such as the motivational approach/withdrawal, valence/arousal, capability, and inhibition asymmetric models. Afterward, the frontal EEG asymmetry of mood was investigated following three research lines, that is considering studies involving different mood induction procedures, dispositional mood (positive and negative affect, and mood alterations in both healthy and clinical populations. In general, results were found to be contradictory, no model is unequivocally supported regardless the research line considered. Different methodological issues were raised, such as: the composition of samples used across studies, in particular, gender and age were found to be critical variables that should be better addressed in future studies; the importance of third variables that might mediate the relationship between frontal EEG asymmetries and mood, for example bodily states and hormonal responses; the role of cognition, namely the interplay between mood and executive functions. In light of these issues, future research directions were proposed. Amongst others, the need to explore the neural connectivity that underpins EEG asymmetries, and the need to include both positive and negative mood conditions in the experimental designs have been highlighted.

  2. Accuracy of Korean-Mini-Mental Status Examination Based on Seoul Neuro-Psychological Screening Battery II Results.

    Science.gov (United States)

    Kang, In-Woong; Beom, In-Gyu; Cho, Ji-Yeon; Son, Hyo-Rim

    2016-05-01

    The Korean-Mini-Mental Status Examination (K-MMSE) is a dementia-screening test that can be easily applied in both community and clinical settings. However, in 20% to 30% of cases, the K-MMSE produces a false negative response. This suggests that it is necessary to evaluate the accuracy of K-MMSE as a screening test for dementia, which can be achieved through comparison of K-MMSE and Seoul Neuropsychological Screening Battery (SNSB)-II results. The study included 713 subjects (male 534, female 179; mean age, 69.3±6.9 years). All subjects were assessed using K-MMSE and SNSB-II tests, the results of which were divided into normal and abnormal in 15 percentile standards. The sensitivity of the K-MMSE was 48.7%, with a specificity of 89.9%. The incidence of false positive and negative results totaled 10.1% and 51.2%, respectively. In addition, the positive predictive value of the K-MMSE was 87.1%, while the negative predictive value was 55.6%. The false-negative group showed cognitive impairments in regions of memory and executive function. Subsequently, in the false-positive group, subjects demonstrated reduced performance in memory recall, time orientation, attention, and calculation of K-MMSE items. The results obtained in the study suggest that cognitive function might still be impaired even if an individual obtained a normal score on the K-MMSE. If the K-MMSE is combined with tests of memory or executive function, the accuracy of dementia diagnosis could be greatly improved.

  3. MENINGKATKAN HASIL BELAJAR BOLA VOLI MINI MELALUI TUTOR SEBAYA SISWA SEKOLAH DASAR

    Directory of Open Access Journals (Sweden)

    Efan Murtiyono

    2015-07-01

    Full Text Available The purpose of the study to determine the learning outcome volleyball mini through peer tutoring approach for fourth grade students Sabarwangi District Subdistrict Kajen Pekalongan.Reseach using action research. The subjects used were fourth grade students of SD Negeri 23 Sabarwangi the number of students consisting of 14 boys and 9 student daughter .Tecnic with observations and data collection dokumentasi.Instrumen used in the data collection was obtained from the test results that show student performance when implementation. Based on the above results, it can be concluded that the application of mini volleyball lessons through peer tutoring approach has a positive effect, which can increase the yield student learning that can facilitate students to understand and perform the movement correctly. Suggestion of this study can be used as an alternative learning materials if there were teachers who experience the same learning problems.

  4. Mini-implants: mechanical resource for molars uprighting

    Directory of Open Access Journals (Sweden)

    Susiane Allgayer

    2013-02-01

    Full Text Available INTRODUCTION: The early orthodontic treatment allows correction of skeletal discrepancies by growth control, and the elimination of deleterious habits, which are risk factors for the development of malocclusions, favoring for the correction of tooth positioning later in a second treatment stage. During development of teeth and occlusion, the mandibular second molars commonly erupt in the oral cavity after all other teeth of the anterior region. In their eruptive process there may be a condition known as tooth impaction, which precludes its complete eruption and requires proper uprighting treatment. The temporary anchorage devices allow disimpaction and movement of these teeth directly to their final position, without the need of patient compliance or reaction movements in other parts of the arch. OBJECTIVE: This paper aims at describing a case report of the treatment of a patient with Angle Class II malocclusion, performed in two phases, in which mini-implants were used for uprighting the impacted mandibular second molars.INTRODUÇÃO: o tratamento ortodôntico precoce permite a correção das discrepâncias esqueléticas por meio do controle de crescimento e a eliminação de hábitos deletérios, que são fatores de risco para o desenvolvimento de más oclusões, que favorecem a correção do posicionamento dentário mais tardiamente, em uma segunda fase do tratamento. Durante o desenvolvimento da dentição e da oclusão, normalmente o segundo molar inferior chega à cavidade bucal após todos os dentes posicionados anteriormente a ele. Durante seu processo eruptivo, pode ocorrer uma condição chamada "impacção dentária", em que sua erupção completa é interrompida, exigindo tratamento apropriado para verticalização. Os dispositivos temporários de ancoragem permitem a desimpacção e a movimentação desses dentes diretamente às suas posições finais, sem a necessidade de cooperação do paciente e sem movimento de reação nas

  5. Designing a mini subcritical nuclear reactor; Diseno de un mini reactor nuclear subcritico

    Energy Technology Data Exchange (ETDEWEB)

    Escobedo G, C. R.; Vega C, H. R.; Davila H, V. M., E-mail: rafelaescobedo@hotmail.com [Universidad Autonoma de Zacatecas, Unidad Academica de Estudios Nucleares, Jardin Juarez 147, Col. Centro, 98000 Zacatecas, Zac. (Mexico)

    2015-10-15

    In this work the design of a mini subcritical nuclear reactor formed by means of light water moderator, uranium as fuel, and isotopic neutron source of {sup 239}PuBe was carried out. The design was done by Monte Carlo methods with the code MCNP5 in which uranium was modeled in an array of concentric holes cylinders of 8.5, 14.5, 20.5, 26.5, 32.5 cm of internal radius and 3 cm of thickness, 36 cm of height. Different models were made from a single fuel cylinder (natural uranium) to five. The neutron source of {sup 239}PuBe was situated in the center of the mini reactor; in each arrangement was used water as moderator. Cross sections libraries Endf/Vi were used and the number of stories was large enough to ensure less uncertainty than 3%. For each case the effective multiplication factor k{sub e}-f{sub f}, the amplification factor and the power was calculated. Outside the mini reactor the ambient dose equivalent H (10) was calculated for different cases. The value of k{sub eff}, the amplification factor and power are directly related to the number of cylinders of uranium as fuel. Although the average energy of the neutrons {sup 239}PuBe is between 4.5 and 5 MeV in the case of the mini reactor for a cylinder, in the neutron spectrum the presence of thermal neutrons does not exist, so that produced fissions are generated with fast neutrons, and in designs of two and three rings the neutron spectra shows the presence of thermal neutrons, however the fissions are being generated with fast neutrons. Finally in the four and five cases the amount of moderator is enough to thermalized the neutrons and thereby produce the fission. The maximum value for k{sub eff} was 0.82; this value is very close to the assembly of Universidad Autonoma de Zacatecas generating a k{sub eff} of 0.86. According to the safety and radiation protection standards for the design of mini reactor of one, two and three cylinders they comply with the established safety, while designs of four and five

  6. Measurements of surgeons' exposure to ionizing radiation dose: comparison of conventional and mini C-arm fluoroscopy.

    Science.gov (United States)

    Sung, K H; Min, E; Chung, C Y; Jo, B C; Park, M S; Lee, K

    2016-03-01

    This study was performed to measure the equivalent scattered radiation dose delivered to susceptible organs while simulating orthopaedic surgery using conventional and mini C-arm fluoroscopy. In addition, shielding effects on the thyroid, thymus, and gonad, and the direct exposure delivered to the patient's hands were also compared. A conventional and mini C-arms were installed in an operating room, and a hand and an operator phantom were used to simulate a patient's hand and a surgeon. Photoluminescence dosimeters were used to measure the equivalent dose by scattered radiation arriving at the thyroid, thymus, and gonad on a whole-body phantom in the position of the surgeon. Equivalent scattered radiation doses were measured in four groups: (1) unshielded conventional C-arm group; (2) unshielded mini C-arm group; (3) lead-shielded conventional C-arm group; and (4) lead-shielded mini C-arm group. Equivalent scattered radiation doses to the unshielded group were significantly lower in the mini C-arm group than those in the conventional C-arm group for all organs. The gonad in the lead-shielded conventional C-arm group showed the highest equivalent dose among operator-susceptible organs, and radiation dose was reduced by approximately 96% compared with that in the unshielded group. Scattered radiation was not detected in any susceptible organ in the lead-shielded mini C-arm group. The direct radiation dose to the hand phantom measured from the mini C-arm was significantly lower than that measured from the conventional C-arm. The results show that the equivalent scattered radiation dose to the surgeon's susceptible organs and the direct radiation dose to a patient's hand can be decreased significantly by using a mini C-arm rather than a conventional C-arm. However, protective lead garments, such as a thyroid shield and apron, should be applied to minimize radiation exposure to susceptible organs, even during use of mini C-arm fluoroscopy. © The Author(s) 2015.

  7. Mini Tracheostomy for Obstructive Sleep Apnea: An Evidence Based Proposal

    Science.gov (United States)

    Camacho, Macario; Zaghi, Soroush; Chang, Edward T.; Song, Sungjin A.; Szelestey, Blake; Certal, Victor

    2016-01-01

    Objective. To search for articles evaluating the use of tracheostomies (either permanent stomas or tracheostomy tubes) in adult obstructive sleep apnea (OSA) patients and to evaluate the potential for the use of mini tracheostomies as treatment for OSA. Study Design. Systematic review. Methods. Nine databases were searched from inception through July 21, 2015. Results. The overall tracheostomy search yielded 516 articles, of which eighteen studies provided polysomnographic data. No study was identified (empty review) for the use of mini tracheostomies for treating OSA. The mini tracheostomy search yielded ninety-five articles which describe findings for either mini tracheostomy kits (inner cannula diameter of 4 mm) or the performance of mini tracheotomies. Six articles described the use of mini tracheostomies as a temporary procedure to relieve acute upper airway obstruction and none described the use for OSA. For tracheostomy stomal sites, suturing the skin directly to the tracheal rings with defatting can minimize stomal site collapse. The smallest tracheostomy stomal size that can successfully treat OSA has not been described. Conclusion. Mini tracheostomies as small as 4 mm have been successfully used in the short term to relieve upper airway obstruction. Given that polysomnography data are lacking, additional research is needed. PMID:26925105

  8. Virtual laboratory of electrical mini-grids with distributed generation

    International Nuclear Information System (INIS)

    Menezes Ramos, Vanessa; Barros Galhardo, Marcos André; Oliveira Barbosa, Claudomiro Fábio de; Tavares Pinho, João

    2015-01-01

    This paper presents a computing tool called Virtual Laboratory de Minirredes (Virtual Laboratory of Mini-grids). Using the virtual environment of the developed tool, it is possible to make remote connection/disconnection of switches and loads (resistive, inductive, capacitive and non-linear) at strategic points of the electric mini-grid with hybrid distributed generation systems (solar photovoltaic-diesel). The mini-grid has a length of about 1 km and is installed in the test area of the Grupo de Estudios e Desenvolvimento de Alternativas Exergética (GEDAE) of the Universidade Federal do Pará, located in the city of Belém, Pará, Brazil. The developed tool has communication functions with electric parameters transducers and programmable logic controllers (PLCs). This communication enables the opening and closing of contactors, resulting in different settings for the mini-grid. In addition to that, based on the proposed configuration by the user, the real-time operation status of mini-grid is presented in a graphic interface (for example, monitored electric parameters, distributed generators connected, status of disconnected switches, etc.) and the acquired data is stored. The use of the computing tool also focuses on the construction of a database, in order to obtain knowledge about the mini-grid performance under various conditions that can be set, depending on the operational strategy adopted, based on the choice of the layout, loads and power sources used in the mini-grid. (full text)

  9. Mini Tracheostomy for Obstructive Sleep Apnea: An Evidence Based Proposal

    Directory of Open Access Journals (Sweden)

    Macario Camacho

    2016-01-01

    Full Text Available Objective. To search for articles evaluating the use of tracheostomies (either permanent stomas or tracheostomy tubes in adult obstructive sleep apnea (OSA patients and to evaluate the potential for the use of mini tracheostomies as treatment for OSA. Study Design. Systematic review. Methods. Nine databases were searched from inception through July 21, 2015. Results. The overall tracheostomy search yielded 516 articles, of which eighteen studies provided polysomnographic data. No study was identified (empty review for the use of mini tracheostomies for treating OSA. The mini tracheostomy search yielded ninety-five articles which describe findings for either mini tracheostomy kits (inner cannula diameter of 4 mm or the performance of mini tracheotomies. Six articles described the use of mini tracheostomies as a temporary procedure to relieve acute upper airway obstruction and none described the use for OSA. For tracheostomy stomal sites, suturing the skin directly to the tracheal rings with defatting can minimize stomal site collapse. The smallest tracheostomy stomal size that can successfully treat OSA has not been described. Conclusion. Mini tracheostomies as small as 4 mm have been successfully used in the short term to relieve upper airway obstruction. Given that polysomnography data are lacking, additional research is needed.

  10. Rehabilitation of resorbed mandibular ridges using mini implant retained overdentures: A case series with 3 year follow-up

    Directory of Open Access Journals (Sweden)

    Pooja Kumari

    2016-01-01

    Full Text Available With the increasing average life expectancy of human beings, the need to cater geriatric patients is ever increasing. Complete dentures are an indispensable tool in this regard. The loose and unstable lower complete denture owing to residual ridge resorption is one of the most common problems faced by edentulous patients. Dental implant retained overdentures have emerged as an efficient treatment modality for such patients. Though useful, not every patient is a suitable candidate to go for conventional implant-borne prosthesis, limitation being the available bone width. In such cases, mini implants may be used for augmenting the retention of the dentures and improving the quality of life of patients. In this case series, rehabilitation of three compromised cases with mini implant retained overdentures have been described wherein patients are experiencing instability of lower denture due to thin resorbed mandibular ridges. In one of the cases, three mini implants placed in A, C, and E position were splinted using a cemented bar to retain the mandibular denture. The other two cases were rehabilitated using unsplinted ball type one piece mini implants placed in A, C, and E position in one case and B and D position in another case. Though splinted bar design should be preferred but the lack of available vertical space precluded the utilization of bar in other two cases. The results were found to be satisfactory with no complications reported during a follow-up period of over 3 years in all the cases.

  11. MINI-THESAURUS, Energy Data Base Subject Thesaurus Generator

    International Nuclear Information System (INIS)

    Paulk, J.W.

    2003-01-01

    1 - Description of program or function: MINI-THESAURUS allows the user to subset into highly-specialized 'mini-thesauri' the Energy Data Base (EDB) Subject Thesaurus, which contains the standard vocabulary of indexing terms (descriptors) developed and structured by the Office of Scientific and Technical Information (OSTI) for the building and maintenance of the U.S. Department of Energy (DOE) energy information databases. This structured vocabulary reflects the scope of DOE's research, development, and technological programs and encompasses terminology derived not only from the basic sciences but also from the areas of energy, conservation, safety, environmental impact, and regulation. Entire word blocks may be copied from the primary Subject Thesaurus, from another mini-thesaurus, or both, and subsequently modified through the addition of new terms, the deletion of existing terms, and changes to the internal relationships among the word blocks within the mini-thesaurus to create a new, special-purpose thesaurus. MINI-THESAURUS also provides the ability to copy the entire Subject Thesaurus and to treat the copy as a mini-thesaurus, thus allowing one to examine the effects of major changes to the thesaurus structure without having to modify the primary, on-line Thesaurus. The copy operation also optimizes the Subject Thesaurus structure. An interactive user having update privileges for a specific mini-thesaurus and access to the TeX and PostScript proprietary software can produce the mini-thesaurus in printed publication format. Once the mini-thesaurus has been published, periodic supplements may be generated based on date of entry or change maintained by the Thesaurus software. 2 Restrictions on the complexity of the problem: The system enforces the OSTI rules for Thesaurus development

  12. Review of the role of the sentinel node biopsy in neoadjuvant chemotherapy in women with breast cancer and negative or positive axillary node at diagnosis.

    Science.gov (United States)

    Ruano Pérez, R; Rebollo Aguirre, A C; García-Talavera San Miguel, P; Díaz Expósito, R; Vidal-Sicart, S; Cordero García, J M; Carrera Salazar, D; Rioja Martín, M E

    The role of the selective sentinel node biopsy (SNB) is increasing in relevance in breast cancer women with indication of neoadjuvant chemotherapy (NAC). The Radiosurgery Working Group of the SEMNIM is aware of the necessity of establishing the need for SNB before or after NAC, and also how to manage patients with axillary node-negative or node-positive. There is sufficient data to assess that the SNB with radioisotope techniques are feasible and safe in all these scenarios. An adequate axilla evaluation prior to surgery and the possibility of marking prior to NAC the nodes infiltrated must be the two main pillars to guarantee the success of the SNB. It has been shown that to incorporate the SNB in breast cancer women with indication of NAC increases the rate of a conservative treatment of the axilla that will be a clear benefit for these patients. Copyright © 2017 Elsevier España, S.L.U. y SEMNIM. All rights reserved.

  13. Mini-conference and Related Sessions on Laboratory Plasma Astrophysics

    International Nuclear Information System (INIS)

    Hantao Ji

    2004-01-01

    This paper provides a summary of some major physics issues and future perspectives discussed in the Mini-Conference on Laboratory Plasma Astrophysics. This Mini-conference, sponsored by the Topical Group on Plasma Astrophysics, was held as part of the American Physical Society's Division of Plasma Physics 2003 Annual Meeting (October 27-31, 2003). Also included are brief summaries of selected talks on the same topic presented at two invited paper sessions (including a tutorial) and two contributed focus oral sessions, which were organized in coordination with the Mini-Conference by the same organizers

  14. Mini-conference and Related Sessions on Laboratory Plasma Astrophysics

    Energy Technology Data Exchange (ETDEWEB)

    Hantao Ji

    2004-02-27

    This paper provides a summary of some major physics issues and future perspectives discussed in the Mini-Conference on Laboratory Plasma Astrophysics. This Mini-conference, sponsored by the Topical Group on Plasma Astrophysics, was held as part of the American Physical Society's Division of Plasma Physics 2003 Annual Meeting (October 27-31, 2003). Also included are brief summaries of selected talks on the same topic presented at two invited paper sessions (including a tutorial) and two contributed focus oral sessions, which were organized in coordination with the Mini-Conference by the same organizers.

  15. Mini-Implants: New Possibilities in Interdisciplinary Treatment Approaches

    Directory of Open Access Journals (Sweden)

    Biju Sebastian

    2014-01-01

    Full Text Available The introduction of mini-implants has broadened the range of tooth movements possible by fixed appliance therapy alone. The limits of fixed orthodontic treatment have become more a matter of facial appearance than anchorage. Many complex cases which would previously have required surgery or functional appliances can now be treated with fixed appliance therapy using mini-implants. A mutilated dentition case where mini-implants were used to provide anchorage for intrusion of molars and retraction of anterior teeth is reported here to illustrate this point.

  16. Orthodontic mechanics using mini-implant measured by FBG

    Science.gov (United States)

    Trannin, Pamela G.; Milczewski, Maura S.; de Oliveira, Walmir; Guariza Filho, Odilon; Lopes, Stephani C. P. S.; Kalinowski, Hypolito J.

    2015-07-01

    The magnitude of the force generated during orthodontic mechanics anchored in mini-implant in a maxilla model was analyzed. Data was collected during the insertion of the mini-implant and at the moment of applying forces to the structure of the maxilla and dentition. To obtain quantitative results, the Fibre Bragg Gratings (FBG) were inserted in an elastomeric material reproducing a maxilla model. It was observed levels of forces of approximately 3,78N next to the root of first premolar by the insertion of the mini-implant and different levels of the force to different orthodontic mechanics applied on the dental system.

  17. Additional value of 16{alpha}-[{sup 18}F]fluoro-17{beta}-oestradiol PET for differential diagnosis between uterine sarcoma and leiomyoma in patients with positive or equivocal findings on [{sup 18}F]fluorodeoxyglucose PET

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, Yoshio; Kurokawa, Tetsuji; Kotsuji, Fumikazu [University of Fukui, Department of Gynecology, Faculty of Medical Sciences, Fukui (Japan); Kiyono, Yasushi; Tsujikawa, Tetsuya; Okazawa, Hidehiko [University of Fukui, Biomedical Imaging Research Center, Fukui (Japan)

    2011-10-15

    Pathological data suggest that the rate of oestrogen receptor (ER) expression in uterine sarcoma is significantly lower than in leiomyoma. The present study aimed to investigate whether ER expression using ER imaging agents for positron emission tomography (PET), of which the most successful has been 16{alpha}-[{sup 18}F]-fluoro-17{beta}-oestradiol (FES), is able to add useful information to the differential diagnosis of uterine sarcoma and leiomyoma in patients with positive or equivocal findings on [{sup 18}F]fluorodeoxyglucose (FDG) PET. A total of 76 patients with suspected uterine sarcoma based on ultrasound and magnetic resonance imaging findings from 2007 to 2010 were enrolled. Twenty-four of the present patients were referred for FES PET because of FDG PET findings that showed equivocal or positive FDG uptake. PET images were quantitatively evaluated with reference to histopathological findings. Receiver-operating characteristic analysis was performed to determine the optimal cutoff value to differentiate uterine sarcoma and leiomyoma. Of the 24 patients, 11 had a final diagnosis of uterine sarcoma, while 13 had leiomyoma. The sensitivity, specificity and accuracy of an FDG to FES standardized uptake value (SUV) ratio greater than 2.0 were significantly higher using Cochran's Q test (p = 0.024) when compared with FDG PET greater than 3.0 alone (90.9 vs 81.8%, 92.3 vs 84.6% and 91.3 vs 83.3%, respectively). Additional FES PET findings confirmed uterine sarcoma in 91.3% of a selected group of patients with equivocal or positive FDG uptake. (orig.)

  18. What leads some people to think they are HIV-positive before knowing their diagnosis? A systematic review of psychological and behavioural correlates of HIV-risk perception.

    Science.gov (United States)

    Evangeli, Michael; Baker, Laura L E; Pady, Kirsten; Jones, Bethanie; Wroe, Abigail L

    2016-08-01

    Current HIV-risk perception refers to the extent to which individuals think they might be HIV-positive. This belief, distinct from the perceived risk about being infected with HIV in the future, is likely to have a range of important consequences. These consequences may include both psychological effects (e.g., impacts on well-being) and behavioural effects (e.g., HIV testing uptake). Given these possible outcomes, and the suggested importance of risk perception in health behaviour models, understanding the behavioural and psychological antecedents of current HIV-risk perception is crucial. This systematic review investigates the relationship between behavioural and psychological factors and current HIV-risk perception (in individuals who are unaware of their actual HIV status). Eight studies were eligible for inclusion in the review (five quantitative and three qualitative studies). Drug risk behaviour and sexual risk behaviour (both self and partner) were often associated with current HIV-risk perception, although other studies failed to show a relationship between one's own sexual risk behaviour and risk perception. Psychological factors were only rarely assessed in relation to current HIV-risk perception. Where these variables were included, there was evidence that experiencing symptoms perceived to be consistent with HIV and prompts to test were associated with increased current HIV-risk perception. These findings are consistent with the Common-Sense Model (CSM) of illness representation and self-regulation. Methodological quality criteria were rarely met for the included studies. In addition, it was often difficult to ascertain whether potentially includable studies were eligible due to imprecise definitions of HIV-risk perception. Research and practice implications are discussed, with particular emphasis on the role of risk appraisals as a potential mediator of the relationship between HIV-risk behaviour, symptoms and current HIV-risk perception.

  19. Mini-percutaneous nephrolithotomy for stones in anomalous-kidneys: a prospective study.

    Science.gov (United States)

    Khadgi, Sanjay; Shrestha, Babu; Ibrahim, Hamdy; Shrestha, Sunil; ElSheemy, Mohammed S; Al-Kandari, Ahmed M

    2017-08-01

    To evaluate safety and efficacy of minipercutaneous nephrolithotomy (Mini-PNL) in management of stones in different types of renal anomalies. Patients with stones ≥2 cm or SWL-resistant stones in anomalous-kidneys treated by Mini-PNL between March 2010 and September 2012 were included prospectively. Mini-PNL was done under regional anesthesia in prone position with fluoroscopic guidance through 18 Fr sheath using semirigid ureteroscope (8.5/11.5 Fr) and pneumatic lithotripter. All patients were followed-up for 2-3 years. Stone-free rate was defined as absence of residual fragments ≥2 mm. Student-T, Mann-Whitney, Chi square (χ 2 ), Fisher-exact, one way ANOVA or Kruskal-Wallis test were used for analysis. Mini-PNL was performed for 59 patients (20 horseshoe, 15 malrotated, 7 polycystic, 13 duplex and 4 ectopic pelvic-kidneys). Mean age was 40.18 ± 12.75 (14-78) years. Mean stone burden was 31.72 ± 21.43 (7.85-141.3) mm 2 . Two tracts were required in 7 (11.9 %) patients. Tubeless Mini-PNL with double-J insertion was performed in all patients except two. Operative time was 50.17 ± 18.73 (15-105) min. Hemoglobin loss was 0.44 ± 0.30 (0-1.4) g/dL. Complications were reported in 15 (25.4 %) patients. No pleural injury, sepsis, perinephric-collection or renal-pelvis perforation were reported. Stone-free rate was 89.8 % (converted to open-surgery in one patient, second-look PNL in two patients, auxiliary SWL in three patients). Stone-free rate improved to 98.3 % after retreatment and auxiliary SWL. Site of puncture was mostly upper calyceal in horseshoe-kidney (80 %), mid calyceal in polycystic-kidney (85.7 %) and lower calyceal in duplex-kidney (46.2 %). Punctures were also significantly infracostal in horseshoe-kidney (100 %) and supracostal in both duplex (53.8 %) and malrotated-kidneys (66.7 %). Mini-PNL is safe for management of stones in anomalous-kidney with SFR comparable to standard-PNL but with less complications.

  20. Morphometry, ultrastructure, myosin isoforms, and metabolic capacities of the "mini muscles" favoured by selection for high activity in house mice.

    Science.gov (United States)

    Guderley, Helga; Houle-Leroy, Philippe; Diffee, Gary M; Camp, Dana M; Garland, Theodore

    2006-07-01

    Prolonged selective breeding of mice (Mus musculus) for high levels of voluntary wheel running has favoured an unusual phenotype ("mini muscles"), apparently caused by a single Mendelian recessive allele, in which most hind-limb muscles are markedly reduced in mass, but have increased mass-specific activities of mitochondrial enzymes. We examined whether these changes reflect changes in fibre size, number or ultrastructure in normal and "mini-muscle" mice within the two (of four) selectively bred lines (lab designations L3 and L6) that exhibit the phenotype at generations 26 and 27. In both lines, the gastrocnemius and plantaris muscles are smaller in mass (by >50% and 20%, respectively) in affected individuals. The mass-specific activities of mitochondrial enzymes in the gastrocnemius and plantaris muscles were increased in the mini phenotype in both lines, with stronger effects in the gastrocnemius muscle. In the gastrocnemius, the % myosin heavy chain (MHC) IIb was reduced by 50% in L3 and by 30% in L6, whereas the % MHC IIa and I were higher, particularly in L3. Fibre number in the plantaris muscle did not significantly differ between mini and normal muscles, although muscle mass was a significant positive correlate of fibre number. Small fibres were more abundant in mini than normal muscles in L3. Mitochondrial volume density was significantly higher in mini than normal muscle fibres in L3, but not in L6. Microscopy revealed a surprising attribute of the mini muscles: an abundance of small, minimally differentiated, myofibril-containing cells positioned in a disorderly fashion, particularly in the surface layer. We hypothesise that these unusual cells may be satellite cells or type IIb fibres that did not complete their differentiation. Together, these observations suggest that mice with the mini phenotype have reduced numbers of type IIb fibres in many of their hind-limb muscles, leading to a decrease in mass and an increase in mass-specific aerobic capacity

  1. Autism: Diagnosis

    Science.gov (United States)

    ... Information Publications Awards Partners Contact Us ¿Qué es Autismo? Donate Home What is Autism? What is Autism? ... Information Publications Awards Partners Contact Us ¿Qué es Autismo? Diagnosis Home / What is Autism? / Diagnosis Expand Medical ...

  2. Internal Structure of Mini-CEX Scores for Internal Medicine Residents: Factor Analysis and Generalizability

    Science.gov (United States)

    Cook, David A.; Beckman, Thomas J.; Mandrekar, Jayawant N.; Pankratz, V. Shane

    2010-01-01

    The mini-CEX is widely used to rate directly observed resident-patient encounters. Although several studies have explored the reliability of mini-CEX scores, the dimensionality of mini-CEX scores is incompletely understood. Objective: Explore the dimensionality of mini-CEX scores through factor analysis and generalizability analysis. Design:…

  3. Low-Cost Mini Radar: Design Prototyping and Tests

    Directory of Open Access Journals (Sweden)

    Dario Tarchi

    2017-01-01

    Full Text Available Radar systems are largely employed for surveillance of wide and remote areas; the recent advent of drones gives the opportunity to exploit radar sensors on board of unmanned aerial platforms. Nevertheless, whereas drone radars are currently available for military applications, their employment in the civilian domain is still limited. The present research focuses on design, prototyping, and testing of an agile, low-cost, mini radar system, to be carried on board of Remotely Piloted Aircraft (RPAs or tethered aerostats. In particular, the paper faces the challenge to integrate the in-house developed radar sensor with a low-cost navigation board, which is used to estimate attitude and positioning data. In fact, a suitable synchronization between radar and navigation data is essential to properly reconstruct the radar picture whenever the platform is moving or the radar is scanning different azimuthal sectors. Preliminary results, relative to tests conducted in preoperational conditions, are provided and exploited to assert the suitable consistency of the obtained radar pictures. From the results, there is a high consistency between the radar images and the picture of the current environment emerges; finally, the comparison of radar images obtained in different scans shows the stability of the platform.

  4. Pulmonary vein isolation using the Rhythmia mapping system: Verification of intracardiac signals using the Orion mini-basket catheter.

    Science.gov (United States)

    Anter, Elad; Tschabrunn, Cory M; Contreras-Valdes, Fernando M; Li, Jianqing; Josephson, Mark E

    2015-09-01

    During pulmonary vein isolation (PVI), a circular lasso catheter is positioned at the junction between the left atrium (LA) and the pulmonary vein (PV) to confirm PVI. The Rhythmia mapping system uses the Orion mini-basket catheter with 64 electrodes instead of the lasso catheter. However, its feasibility to determine PVI has not been studied. The purpose of this study was to compare signals between the mini-basket and lasso catheters at the LA-PV junction. In 12 patients undergoing PVI using Rhythmia, the mini-basket and lasso catheters were placed simultaneously at the LA-PV junction for baseline and post-PVI signal assessment. Pacing from both catheters was performed to examine the presence of exit block. At baseline, recordings of LA and PV potentials were concordant in all PVs. However, after PVI, concordance between the catheters was only 68%. Discordance in all cases resulted from loss of PV potentials on the lasso catheter with persistence of PV potentials on the mini-basket catheter. In 9 of 13 PVs (69%), these potentials represented true PV potentials that were exclusively recorded with the smaller and closely spaced mini-basket electrodes. In the other 4 PVs (31%), these potentials originated from neighboring structures and resulted in underestimation of PVI. The use of the mini-basket catheter alone is sufficient to determine PVI. While it improves recording of PV potentials after incomplete ablation, it is also associated with frequent recording of "PV-like" potentials originating from neighboring structures. In these cases, pacing maneuvers are helpful to determine PVI and avoid excessive ablation. Copyright © 2015 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

  5. Economics of Mini tuber Seed Yam Production Technique in South ...

    African Journals Online (AJOL)

    Marcel

    Socio-economic studies on yam production conducted in Nigeria include Lageman (1977) .... the profitability of the mini tuber seed yam production technique as a guide .... production (with particular reference to Root Crops in the West Indies).

  6. Mini-chamber, an advanced protection concept for NIF

    International Nuclear Information System (INIS)

    Peterson, P.F.; Scott, J.M.

    1996-01-01

    Inertial confinement fusion (ICF) target debris and ablated near-target materials pose the primary threat to the National Ignition Facility (NIF) final optics debris shields, as well as a major challenge in future inertial fusion energy (IFE) power plants. This work discusses a NIF 'mini-chamber,' designed to mitigate the debris threat. Although the NIF base-line design protects against debris using a frost-protected target positioner and refractory first-wall coatings, the mini-chamber provides important flexibility in three areas: debris-shield protection from beyond-design basis shots (i.e. heavy hohlraums, special diagnostics, shields); fielding of large experiments with significant surface ablation; and studying key ablation and gas-dynamics issues for liquid-wall IFE power plants. Key mini-chamber modeling results are presented, followed by discussion of equipment requirements for fielding a NIF mini-chamber. 7 refs., 3 figs

  7. Development of mini-LIA and primary experiments

    International Nuclear Information System (INIS)

    Cheng Cheng; Liao Shuqing; Zheng Shuxin; Lin Yuzheng; Tang Chuanxiang; Jing Xiaobing; Mu Fan; Pan Haifeng; Zhang Kaizhi; Shi Jinshui; Deng Jianjun

    2009-01-01

    Mini-LIA is a miniature of a linear induction accelerator developed by China Academy of Engineering Physics and Tsinghua University in 2007. It has been constructed with a thermionic cathode in an electron injector and a metglas core in the induction accelerator cavities. A double-pulsed electron beam was produced for the first time in China on the Mini-LIA with a thermionic cathode in the electron gun and a metglas core in the induction accelerator cavities. A double-pulsed beam current of more than 1.1A was obtained on condition of 80 kV double-pulsed high voltage produced by pulsed power system supplying to the injector and accelerating modules. Some primary experiments for measuring the parameters of Mini-LIA has been performed, and some beam characterizations of Mini-LIA are presented. Further improvement is underway. (authors)

  8. Implementation of a linear mini accelerator for radiotherapy intraoperative

    International Nuclear Information System (INIS)

    Macias-Verde, D.; Yanez-Lopez, D.; Marti-Asenjo, J.; Sanchez-Carrascal, M.; Torres-Pozas, S.; Godoy-Cazorla, J. I.; Madan-Rodriguez, C.; Martin-Oliva, R.

    2013-01-01

    Has been defined the status initial reference of the lineal mini-accelerator Intrabeam PRS 500. The alternative worksheet in times of treatment provides an additional verification. The system is validated for clinical use. (Author)

  9. Mini-Split Heat Pumps Multifamily Retrofit Feasibility Study

    Energy Technology Data Exchange (ETDEWEB)

    Dentz, Jordan [ARIES Collaborative, New York, NY (United States); Podorson, David [ARIES Collaborative, New York, NY (United States); Varshney, Kapil [ARIES Collaborative, New York, NY (United States)

    2014-05-01

    Mini-split heat pumps can provide space heating and cooling in many climates and are relatively affordable. These and other features make them potentially suitable for retrofitting into multifamily buildings in cold climates to replace electric resistance heating or other outmoded heating systems. This report investigates the suitability of mini-split heat pumps for multifamily retrofits. Various technical and regulatory barriers are discussed and modeling was performed to compare long-term costs of substituting mini-splits for a variety of other heating and cooling options. A number of utility programs have retrofit mini-splits in both single family and multifamily residences. Two such multifamily programs are discussed in detail.

  10. Orthodontic intrusion : Conventional and mini-implant assisted intrusion mechanics

    Directory of Open Access Journals (Sweden)

    Anup Belludi

    2012-01-01

    intrusion has revolutionized orthodontic anchorage and biomechanics by making anchorage perfectly stable. This article addresses various conventional clinical intrusion mechanics and especially intrusion using mini-implants that have proven effective over the years for intrusion of maxillary anteriors.

  11. Mäo kolmnurka kerkib mini-Eesti / Rein Sikk

    Index Scriptorium Estoniae

    Sikk, Rein, 1961-

    2010-01-01

    Järvamaale Mäo kolmnurka kavandatavast Eestimaad vähendatuna näitavast teemapargist mini-Eesti, mis peaks valmima 2014. aastaks. Kavandatavast Narva vanalinna rekonstruktsioonist maketina, mis peaks tulema umber 200 korda 400 meetri suurune

  12. Micropropagation of Ajuga species: a mini review.

    Science.gov (United States)

    Park, Han Yong; Kim, Doo Hwan; Sivanesan, Iyyakkannu

    2017-09-01

    The genus Ajuga L., belonging to Lamiaceae family, is widespread. The demand for Ajuga species has risen sharply because of their medicinal, ornamental, and pharmacological properties. These wide-ranging plants are being rapidly depleted due to over-collection for ornamental and medicinal purposes, as well as by habitat destruction and deforestation. Ajuga boninsimae, A. bracteosa, A. ciliate, A. genevensis, A. incisa, A. makinoi, A. multiflora, A. pyramidalis, A. shikotanensis, A. reptans, and A. vestita are categorized and protected as endangered plants. In vitro plant culture has therefore emerged for the conservation and mass clonal propagation of rare plants. This mini-review covers the current in vitro scenario in the propagation of Ajuga species. Adventitious or axillary shoots are initiated on the leaf, petiole and internodes, as well as roots, nodes, and shoot tip explants. Shoot induction is predominantly dependent on plant growth regulators added to the culture medium. Full- or half-strength Murashige and Skoog medium with or without auxin is used for in vitro rooting. Rooted shoots need to be acclimatized in the greenhouse with an estimated 82-100% survival rate.

  13. Modelo cinematico del mini robot movil Ricimaf

    Directory of Open Access Journals (Sweden)

    Abelardo del Pozo Quintero

    2012-12-01

    Full Text Available El presente trabajo describe el modelo dinámico del mini robot móvil construido en el Icimaf, cuya  tracción se logra mediante dos motores de paso acoplados a dos ruedas plásticas forradas con una capa de goma para facilitar su  movimiento y una pequeña rueda direccional. Se elabora la estructura jacobiana necesaria para el desarrollo del modelo dinámico. Se incluye el análisis de un rasgo especial de estos robots, que  es su naturaleza no holonómica, en contraste  con los robots manipuladores, lo que da lugar a un tipo de restricción del movimiento. La elaboración del modelo dinámico originó el empleo de los multiplicadores de Lagrange. Para la obtención de las ecuaciones dinámicas se emplea el método de Euler-Lagrange

  14. Mini table de radionucléides

    CERN Document Server

    2015-01-01

    Cette table est un outil pratique et quotidien pour tous les travailleurs opérant au contact de radionucléides. Elle concerne tous les secteurs scientifiques et techniques, comme la médecine, la recherche ou l'industrie. La Mini Table de radionucléides a été conçue comme un instrument permettant de repérer et valider rapidement les principales caractéristiques des radionucléides les plus utilisés (environ 300) que l'on rencontre en milieu médical, industriel, nucléaire, gestion des déchets, etc. Présentée en format de poche, elle permet pour chaque radionucléide d'indiquer ses caractéristiques fondamentales : La période radioactive ; Le ou les principaux modes de désintégration ; Les principales émissions en termes d'énergie et d'intensité. Pour des caractéristiques complètes, l'ouvrage renvoie aux Tables de Données de référence. Au sein du CEA, le Laboratoire National Henri Becquerel (LNHB) est mandaté par le Laboratoire National de Métrologie et d'Essais (LNE) comme laboratoir...

  15. Invited Article: miniTimeCube

    Energy Technology Data Exchange (ETDEWEB)

    Li, V. A., E-mail: vli2@hawaii.edu; Dorrill, R.; Duvall, M. J.; Koblanski, J.; Sakai, M.; Learned, J. G.; Macchiarulo, L.; Matsuno, S.; Murillo, J.; Rosen, M.; Varner, G. S. [Department of Physics and Astronomy, University of Hawaii at Manoa, Honolulu, Hawaii 96822 (United States); Negrashov, S. [Department of Physics and Astronomy, University of Hawaii at Manoa, Honolulu, Hawaii 96822 (United States); Department of Information and Computer Sciences, University of Hawaii at Manoa, Honolulu, Hawaii 96822 (United States); Wipperfurth, S. A.; Engel, K.; McDonough, W. F. [Department of Geology, University of Maryland, College Park, Maryland 20742 (United States); Jocher, G. R.; Nishimura, K. [Ultralytics LLC, Arlington, Virginia 22203 (United States); Mumm, H. P. [National Institute of Standards and Technology, 100 Bureau Dr., Gaithersburg, Maryland 20899 (United States); Usman, S. M. [Exploratory Science and Technology Branch, National Geospatial-Intelligence Agency, Springfield, Virginia 22150 (United States); Department of Geography and Geoinformation Science, George Mason University, Fairfax, Virginia 22030 (United States)

    2016-02-15

    We present the development of the miniTimeCube (mTC), a novel compact neutrino  detector. The mTC is a multipurpose detector, aiming to detect not only neutrinos but also fast/thermal neutrons. Potential applications include the counterproliferation of nuclear materials and the investigation of antineutrino short-baseline effects. The mTC is a plastic 0.2% {sup 10}B–doped scintillator (13 cm){sup 3} cube surrounded by 24 Micro-Channel Plate (MCP) photon detectors, each with an 8 × 8 anode totaling 1536 individual channels/pixels viewing the scintillator. It uses custom-made electronics modules which mount on top of the MCPs, making our detector compact and able to both distinguish different types of events and reject noise in real time. The detector is currently deployed and being tested at the National Institute of Standards and Technology Center for Neutron Research nuclear reactor (20 MW{sub th}) in Gaithersburg MD. A shield for further tests is being constructed, and calibration and upgrades are ongoing. The mTC’s improved spatiotemporal resolution will allow for determination of incident particle directions beyond previous capabilities.

  16. Mini Smart Grid @ Copenhagen Business School

    DEFF Research Database (Denmark)

    Pedersen, Rasmus U.; Furtak, Simon J.; Häuser, Ivan

    2013-01-01

    Project Smart Grid: The Intelligent Electrical System Is the Way Forward In 2012 Peter Møllgaard from Department of Economics and Rasmus Pedersen from Department of IT Management initiated a new project supported by CBS Sustainability Platform. The purpose of the project is to establish an unders......Project Smart Grid: The Intelligent Electrical System Is the Way Forward In 2012 Peter Møllgaard from Department of Economics and Rasmus Pedersen from Department of IT Management initiated a new project supported by CBS Sustainability Platform. The purpose of the project is to establish...... an understanding of micro-economic and IT challenges related to Smart Grid technology. The mini-smart-grid project at Copenhagen Business School (MSC@CBS) project seeks to investigate the business opportunities and issues that arise from this new technology. The project revolves around the concepts of Smart Grids......, Smart Meters and prosumers. Smart Grids are a new method of managing electricity and power supply. It has not reached its full potential yet, but it offers a more interactive platform for both the consumer and the main supplier e.g. Dong Energy. The Smart Grid will collect and control the behavior...

  17. Classification of mini-dimmings associated with extreme ultraviolet eruptions by using graph theory

    Directory of Open Access Journals (Sweden)

    S Bazargan

    2016-09-01

    Full Text Available Coronal dimmings in both micro and macro scales, can be observed by extreme ultraviolet images, recorded from Solar Dynamics Observatory or Atmospheric Imaging Assembly (SDO/AIA. Mini-dimmings are sometimes associated with wave-like brightening, called coronal mass ejections. Here, the sun full disk images with 171 Å wavelenght, cadence of 2.5, and  0.6 arcsec cell size, were taken on 3 March 2012, then the obtained data were analyzed. Using Zernike Moment and Support Vector Machine (SVM, mini dimmings are detected. 538 active region events, 680 coronal hole events and 723 quiet sun events have been recognized using algorithm. The position, time duration and spatial expansion of these events were computed .The eruptive dimmings have a more spatial development than thermal dimmings after eruptions. This is evident in their graph characteristics length. Then, using graph theory, eruptive and thermal mini-dimmings were classified, with 13% error, for 200 dimmings. 68 dimmings were classified as thermal, and 132 as eruptive. To do this, evolution of graph characteristic length were used.

  18. Prosthetic Rehabilitation of Child Victim of Avulsion of Anterior Teeth with Orthodontic Mini-Implant

    Directory of Open Access Journals (Sweden)

    Natalice Sousa de Oliveira

    2017-01-01

    Full Text Available The treatment of choice in cases of avulsed permanent teeth is the immediate reimplantation. However, this conduct does not always work favorably, either by failures in the initial approach or by inappropriate interventions. In this sense, the aim of this study is to present an alternative prosthetic rehabilitation with the use of orthodontic mini-implants in the anterior region. This case reports a ten-year-old child with history of avulsion of superior central incisors. The therapeutic approach was planned to promote physiological teeth contacts and acceptable esthetics and phonetics. First, the occlusal-gingival insertion of two orthodontic mini-implants was performed in the alveolar ridge, and, immediately after that, two provisional crowns were attached to the implants. The interventions achieved satisfactory cosmetic and functional results. After one-year follow-up, the adjacent periodontal tissues remained without signs and/or symptoms of inflammation. The provisional crowns presented no mobility and fractures. During radiographic examination, a healthy bone tissue appearance was observed. The simplicity of mini-implant installation makes them a promising alternative for temporary prosthetic rehabilitation of patients undergoing growth and development. The technique provides positive aesthetic and functional results that may reflect on self-esteem and social inclusion of children and adolescents.

  19. Afrique : ressources minières, environnement et gouvernance ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    25 janv. 2011 ... ils regorgent de richesses inouïes », assure Bonnie Campbell, directrice du Groupe de recherche sur les activités minières en Afrique (GRAMA) et titulaire de la Chaire C.-A. Poissant de recherche sur la gouvernance et l'aide au développement, faisant référence aux ressources minières et pétrolières dont ...

  20. Mini-Membrane Evaporator for Contingency Spacesuit Cooling

    Science.gov (United States)

    Makinen, Janice V.; Bue, Grant C.; Campbell, Colin; Petty, Brian; Craft, Jesse; Lynch, William; Wilkes, Robert; Vogel, Matthew

    2015-01-01

    The next-generation Advanced Extravehicular Mobility Unit (AEMU) Portable Life Support System (PLSS) is integrating a number of new technologies to improve reliability and functionality. One of these improvements is the development of the Auxiliary Cooling Loop (ACL) for contingency crewmember cooling. The ACL is a completely redundant, independent cooling system that consists of a small evaporative cooler--the Mini Membrane Evaporator (Mini-ME), independent pump, independent feedwater assembly and independent Liquid Cooling Garment (LCG). The Mini-ME utilizes the same hollow fiber technology featured in the full-sized AEMU PLSS cooling device, the Spacesuit Water Membrane Evaporator (SWME), but Mini-ME occupies only approximately 25% of the volume of SWME, thereby providing only the necessary crewmember cooling in a contingency situation. The ACL provides a number of benefits when compared with the current EMU PLSS contingency cooling technology, which relies upon a Secondary Oxygen Vessel; contingency crewmember cooling can be provided for a longer period of time, more contingency situations can be accounted for, no reliance on a Secondary Oxygen Vessel (SOV) for contingency cooling--thereby allowing a reduction in SOV size and pressure, and the ACL can be recharged-allowing the AEMU PLSS to be reused, even after a contingency event. The first iteration of Mini-ME was developed and tested in-house. Mini-ME is currently packaged in AEMU PLSS 2.0, where it is being tested in environments and situations that are representative of potential future Extravehicular Activities (EVA's). The second iteration of Mini-ME, known as Mini-ME2, is currently being developed to offer more heat rejection capability. The development of this contingency evaporative cooling system will contribute to a more robust and comprehensive AEMU PLSS.

  1. Spurious RF signals emitted by mini-UAVs

    Science.gov (United States)

    Schleijpen, Ric (H. M. A.); Voogt, Vincent; Zwamborn, Peter; van den Oever, Jaap

    2016-10-01

    This paper presents experimental work on the detection of spurious RF emissions of mini Unmanned Aerial Vehicles (mini-UAV). Many recent events have shown that mini-UAVs can be considered as a potential threat for civil security. For this reason the detection of mini-UAVs has become of interest to the sensor community. The detection, classification and identification chain can take advantage of different sensor technologies. Apart from the signatures used by radar and electro-optical sensor systems, the UAV also emits RF signals. These RF signatures can be split in intentional signals for communication with the operator and un-intentional RF signals emitted by the UAV. These unintentional or spurious RF emissions are very weak but could be used to discriminate potential UAV detections from false alarms. The goal of this research was to assess the potential of exploiting spurious emissions in the classification and identification chain of mini-UAVs. It was already known that spurious signals are very weak, but the focus was on the question whether the emission pattern could be correlated to the behaviour of the UAV. In this paper experimental examples of spurious RF emission for different types of mini-UAVs and their correlation with the electronic circuits in the UAVs will be shown

  2. Congenital hypogonadotropic hypogonadism: implications of absent mini-puberty.

    Science.gov (United States)

    Dwyer, Andrew A; Jayasena, Channa N; Quinton, Richard

    2016-06-01

    The phenomenon known as "mini-puberty" refers to activation of the neonatal hypothalamo-pituitary axis causing serum concentrations of gonadotrophins and testosterone (T) to approach adult male levels. This early neonatal period is a key proliferative window for testicular germ cells and immature Sertoli cells. Although failure to spontaneously initiate (adolescent) puberty is the most evident consequence of a defective gonadotropin-releasing hormone (GnRH) neurosecretory network, absent mini-puberty is also likely to have a major impact on the reproductive phenotype of men with congenital hypogonadotrophic hypogonadism (CHH). Furthermore, the phase of male mini-puberty represents a key window-of-opportunity to identify congenital GnRH deficiency (either isolated CHH, or as part of combined pituitary hormone deficiency) in childhood. Among male neonates exhibiting "red flag" indicators for CHH (i.e. maldescended testes with or without cryptorchidism) a single serum sample (between 4-8 weeks of life) can pinpoint congenital GnRH deficiency far more rapidly and with much greater accuracy than dynamic tests performed in later childhood or adolescence. Potential consequences for missing absent mini-puberty in a male neonate include the lack of monitoring of pubertal progression/lack of progression, and the missed opportunity for early therapeutic intervention. This article will review our current understanding of the mechanisms and clinical consequences of mini-puberty. Furthermore, evidence for the optimal clinical management of patients with absent mini-puberty will be discussed.

  3. Perlindungan Hukum Hak Kekayaan Intelektual (Hki) Dalam Waralaba Retail Mini Market Di Yogyakarta Mini Market Di Yogyakarta

    OpenAIRE

    Hariyanto Hariyanto, S.H., M.KN

    2009-01-01

    The Law Protection Intellectual Property Right in Mini Market Retail Franchise in YogyakartaFranchise business is more happening in Indonesia. This fast development indicates an interesting investment which on the same time helps the business subjects in starting their own business with a low risk. The franchise business which commonly stable is retail business. One of retail business which serves the main needs and daily needs is mini market Alfamart and Indomaret.This research aims to ident...

  4. Mini and micro hydropower systems in India

    International Nuclear Information System (INIS)

    Kothari, D.P.

    1992-01-01

    Hydropower is one of the renewable sources of energy. In the field of hydropower, even though small/mini/micro hydropower systems make fractional increases in the overall energy production, their impact on the local areas in which they are sited can be significant in stimulating growth of rural industry and in meeting the basic energy needs of the local population for domestic and agricultural use. They also help in reducing demand on other non-renewable polluting resources like fossil fuels. Moreover as compared to big hydropower systems, small hydropower systems are cost competitive and minimally disruptive to the environment. They require less time for construction and reduce transmission losses. They can be designed to suit the limits of water resources available and can be tailored to the needs of the end-use market. Aspects of small hydropower projects which needs to be studied are listed. Modelling of turbines and generators for such projects, and factors to be considered in selection of suitable turbine and generator for a particular small hydropower system are discussed. The technology for small hydropower systems is well developed and available in India. The present estimated potential of such systems in India is 5000 MW out of which 207 MW is harnessed. These small hydropower plants are mostly located in the northern states like Jammu and Kashmir, Uttar Pradesh, Punjab, and Rajasthan. Construction works for 234 MW at 88 sites are going on. During the 8th plan period, 218.5 MW is planned to be developed with an outlay of Rs. 548.25 crores. It is suggested that special subsidies and liberal term loans should be made available for implementing such systems. (M.G.B.). 8 refs., 2 tabs., 1 fig

  5. Fecal specimens preparation methods for PCR diagnosis of human taeniosis

    Directory of Open Access Journals (Sweden)

    Nunes Cáris Maroni

    2006-01-01

    Full Text Available Sample preparation and DNA extraction protocols for DNA amplification by PCR, which can be applied in human fecal samples for taeniasis diagnosis, are described. DNA extracted from fecal specimens with phenol/chloroform/isoamilic alcohol and DNAzol® reagent had to be first purified to generate fragments of 170 pb and 600 pb by HDP2-PCR. This purification step was not necessary with the use of QIAmp DNA stool mini kit®. Best DNA extraction results were achieved after eggs disruption with glass beads, either with phenol/chloroform/isoamilic alcohol, DNAzol® reagent or QIAmp DNA stool mini kit®.

  6. Myosin heavy chain isoform expression in adult and juvenile mini-muscle mice bred for high-voluntary wheel running.

    Science.gov (United States)

    Talmadge, Robert J; Acosta, Wendy; Garland, Theodore

    2014-11-01

    The myosin heavy chain (MyHC) isoform composition of locomotor and non-locomotor muscles of mini-muscle mice were assessed at the protein and mRNA levels in both adult and juvenile (21 day old) mice. Mini-muscle mice are one outcome of a replicated artificial selection experiment in which four lines of mice were bred for high voluntary wheel running (HR lines). Two of the lines responded with an increase in frequency of a single nucleotide polymorphism in an intron in the MyHC-2b gene (myh4) that when homozygous causes a dramatic reduction in triceps surae mass. We found that both locomotor and non-locomotor muscles of adult mini-muscle mice displayed robust reductions, but not elimination, of the MyHC-2b isoform at both the protein and mRNA levels, with commensurate increases in MyHC-2x and sometimes MyHC-2a, as compared with either a line of HR mice that does not display the mini-muscle phenotype or inbred C57Bl6 mice. Immunohistochemical analyses revealed that locomotor muscles of mini-muscle mice contain fibers that express the MyHC-2b isoform, which migrates normally in SDS-PAGE gels. However, these MyHC-2b positive fibers are generally smaller than the surrounding fibers and smaller than the MyHC-2b positive fibers of non-mini-muscle mice, resulting in characteristically fast muscles that lack a substantial MyHC-2b positive (superficial) region. In contrast, the masseter, a non-locomotor muscle of mini-muscle mice contained MyHC-2b positive fibers that stained more lightly for MyHC-2b, but appeared normal in size and distribution. In adults, many of the MyHC-2b positive fibers in the mini-muscle mice also display central nuclei. Only a small proportion of small MyHC-2b fibers in mini-muscle mice stained positive for the neural cell adhesion molecule, suggesting that anatomical innervation was not compromised. In addition, weanling (21 day old), but not 5 day old mice, displayed alterations in MyHC isoform content at both the protein and mRNA levels, including

  7. The Factors of Local Energy Transition in the Seoul Metropolitan Government: The Case of Mini-PV Plants

    Directory of Open Access Journals (Sweden)

    Jae-Seung Lee

    2017-03-01

    Full Text Available As a way of enhancing urban sustainability, Seoul Special City, the capital of South Korea, has shown strong enthusiasm for urban energy transition by tackling climate change and expanding renewable energy. The Seoul Metropolitan Government (SMG has adopted the “One Less Nuclear Power Plant (OLNPP” strategy since April 2012 and specific policy measures, including a mini-photovoltaic (PV plant program, were introduced to facilitate the energy transition. However, varying degrees of success were achieved by 25 district-level local governments (Gu with mini-PV plant programs. This study explored the reason why those local governments showed different levels of performance despite the strong will of municipal government (SMG to implement urban energy transitions through the mini-PV plant program. The tested hypotheses were based on capacity, political context, public awareness and geographical diffusion. The findings indicated that institutional capacity, financial dependence, political orientation and public perception had positively affected the performance of mini-PV plant installation at each district level. Especially, the political will of each district mayor played an important role in the implementation of the policy.

  8. The influence of the noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) resection diagnosis on the false-positive thyroid cytology rate relates to quality assurance thresholds and the application of NIFTP criteria.

    Science.gov (United States)

    Ohori, N Paul; Wolfe, Jenna; Carty, Sally E; Yip, Linwah; LeBeau, Shane O; Berg, Aaron N; Schoedel, Karen E; Nikiforov, Yuri E; Seethala, Raja R

    2017-09-01

    Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is a newly defined entity and recent studies have suggested a decrease of a few percentage points in the rate of malignancy (ROM) for the positive-for-malignancy (PFM) cytology category as a result of NIFTP implementation. However, the distinction between a diagnosis of PFM and one of suspicious for malignancy (SFM) may depend on a variety of factors. In the current study, the authors investigated the ROM for the PFM and SFM diagnoses before and after histologic NIFTP reclassification. Cytology cases with PFM and SFM diagnoses and subsequent surgical resection specimens were searched in the files of the study institution from September 2008 to September 2016. The surgical pathology cases of noninvasive encapsulated follicular variant of papillary thyroid carcinoma were reexamined to determine whether they qualified for NIFTP. The distinct ROMs for the PFM and SFM cases were calculated accordingly. The authors' search identified 338 cases of PFM and 139 cases of SFM with a resection outcome. Before NIFTP reclassification, the PFM cases had a ROM of 99.4%; after NIFTP reclassification, the ROM was 99.1% (P = .6861). The ROM of the SFM cases decreased from 75.5% to 66.9% with NIFTP reclassification (P = .1402). One case in the PFM group and 6 cases in the SFM group could not be verified due to insufficient sampling. In the current large series, NIFTP reclassification did not appear to significantly alter the high ROM for the PFM diagnosis. The authors attribute this finding to a strict quality assurance policy, an emphasis on key cytologic criteria, and systematic application of the NIFTP criteria to follicular-patterned lesions. Cancer Cytopathol 2017;125:692-700. © 2017 American Cancer Society. © 2017 American Cancer Society.

  9. Recommended safety objectives, principles and requirements for mini-reactors

    International Nuclear Information System (INIS)

    1991-05-01

    Canadian and international publications containing objectives, principles and requirements for the safety of nuclear facilities in general and nuclear power plants in particular have been reviewed for their relevance to mini-reactors. Most of the individual recommendations, sometimes with minor wording changes, are applicable to mini-reactors. However, some prescriptive requirements for the shutdown, emergency core cooling and containment systems of power reactors are considered inappropriate for mini-reactors. The Advisory Committee on Nuclear Safety favours a generally non-prescriptive approach whereby the applicant for a mini-reactor license is free to propose any means of satisfying the fundamental objectives, but must convince the regulatory agency to that effect. To do so, a probabilistic safety assessment (PSA) would be the favoured procedure. A generic PSA for all mini-reactors of the same design would be acceptable. Notwithstanding this non-prescriptive approach, the ACNS considers that it would be prudent to require the existence of at least one independent shutdown system and two physically independent locations from which the reactor can be shut down and the shutdown condition monitored, and to require provision for an assumed loss of integrity of the primary cooling system's boundary unless convincing arguments to the contrary are presented. The ACNS endorses in general the objectives and fundamental principles proposed by the interorganizational Small Reactor Criteria working group, and intends to review and comment on the documents on specific applications to be issued by that working group

  10. Evaluation of mini super computers for nuclear design applications

    International Nuclear Information System (INIS)

    Altomare, S.; Baradari, F.

    1987-01-01

    The evolution of the mini super computers will force changes from the current environment of performing nuclear design calculations on mainframe computers (such as a CRAY) to mini super computers. This change will come about for a number of reasons. First, the mini super computers currently available in the marketplace offer the power and speed comparable to mainframes and can provide the capability to support highly computer intensive calculations. Second, the equipment is physically smaller and can easily be installed and operated without extensive investments in facilities and operations support. Third, the computer capacity can be acquired with as much needed memory, disk, and tape capacity as may be needed. Another reasons is that the performance/cost ratio has increased drastically as hardware costs have decreased. A study was conducted at the Westinghouse Commercial Nuclear Fuel Division (CNFD) to evaluate the mini super computers for use in nuclear core design. As a result of this evaluation, Westinghouse CNFD is offering a combined hardware/software technology transfer package for core design. This package provides the utility designer with a totally dedicated mini super computer comparable in speed to the CRAY 1S with sufficient capacity for a sizable design group to perform the engineering activities related to nuclear core design and operations support. This also assures the utility of being totally compatible with the CNFD design codes, thus assuring total update compatibility

  11. Mini AERCam Inspection Robot for Human Space Missions

    Science.gov (United States)

    Fredrickson, Steven E.; Duran, Steve; Mitchell, Jennifer D.

    2004-01-01

    The Engineering Directorate of NASA Johnson Space Center has developed a nanosatellite-class free-flyer intended for future external inspection and remote viewing of human spacecraft. The Miniature Autonomous Extravehicular Robotic Camera (Mini AERCam) technology demonstration unit has been integrated into the approximate form and function of a flight system. The spherical Mini AERCam free flyer is 7.5 inches in diameter and weighs approximately 10 pounds, yet it incorporates significant additional capabilities compared to the 35 pound, 14 inch AERCam Sprint that flew as a Shuttle flight experiment in 1997. Mini AERCam hosts a full suite of miniaturized avionics, instrumentation, communications, navigation, imaging, power, and propulsion subsystems, including digital video cameras and a high resolution still image camera. The vehicle is designed for either remotely piloted operations or supervised autonomous operations including automatic stationkeeping and point-to-point maneuvering. Mini AERCam is designed to fulfill the unique requirements and constraints associated with using a free flyer to perform external inspections and remote viewing of human spacecraft operations. This paper describes the application of Mini AERCam for stand-alone spacecraft inspection, as well as for roles on teams of humans and robots conducting future space exploration missions.

  12. Mini-mental state exam for children (MMC) in children with hemiplegic cerebral palsy.

    Science.gov (United States)

    Moura, Ricardo; Andrade, Peterson Marco Oliveira; Fontes, Patrícia Lemos Bueno; Ferreira, Fernanda Oliveira; Salvador, Larissa de Souza; Carvalho, Maria Raquel Santos; Haase, Vitor Geraldi

    2017-01-01

    Cognitive impairment is frequent in cerebral palsy (CP) and there is a lack of multiprofessional screening instruments. The aim of this study was to investigate the utility of the Mini-Mental State Examination for Children (MMC), an adapted version of the Mini-Mental State Examination, in screening for cognitive impairments in children with CP. We assessed 397 Brazilian children, 310 with typical development and 87 with CP (hemiplegic and quadriplegic forms), aged 5-16 years. Association between the MMC and general intelligence was assessed by the Colored Progressive Matrices instrument. Psychometric indexes for the MMC were adequate. ROC analyses revealed effective diagnostic accuracy in all ages assessed. Cut-off values are reported. Major difficulties on the MMC were observed in children with CP, particularly individuals with the quadriplegic form. Moreover, the MMC showed moderate correlation with the intelligence test, and was reliable in discriminating, among clinical cases, those with poorer cognitive abilities. The MMC could be useful as a multiprofessional screening instrument for cognitive impairment in children with hemiplegic CP. Results of the MMC in quadriplegic CP children should be interpreted with caution. Diagnosis should be confirmed by further psychological testing.

  13. Interrelationship between Mini-Mental State Examination scores and biochemical parameters in patients with mild cognitive impairment and Alzheimer's disease.

    Science.gov (United States)

    Vasantharekha, Ramasamy; Priyanka, Hannah P; Swarnalingam, Thangavel; Srinivasan, Avathvadi Venkatesan; ThyagaRajan, Srinivasan

    2017-10-01

    The aim of the present study was to provide first-hand information about the prevalence of mild cognitive impairment (MCI) and Alzheimer's disease (AD) in Tamil Nadu, a southern state in India, and examine if there exists a relationship between cognitive functions and biochemical parameters in these patients. Surveys were collected from adults, older men and women (n = 3126) from different regions of Tamil Nadu, which were followed up after 12 months for 1337 participants. Mini-Mental State Examination (MMSE) scores, lipid profile, and liver function tests were carried out in the elderly, MCI and AD patients. Based on the MMSE scores, the elderly population was classified into old control (28.97 ± 1.49; n = 1868), MCI (19.58 ± 1.17; n = 734) and AD (7.18 ± 1.38; n = 304) groups. Peripheral blood samples were collected after overnight fast from both male and female volunteers (n = 40 per group) who were categorized as young adult control, old control, MCI and AD. AD patients showed lower MMSE scores compared with the young adults, old and MCI groups, and MMSE further decreased at follow-up examination a year later. In the serum of AD patients, high-density lipoprotein, alkaline phosphatase activity and bilirubin levels were lower, whereas low-density lipoprotein, total cholesterol and triglycerides levels were higher. MMSE was positively correlated with high-density lipoprotein, and negatively correlated with other lipid parameters in AD. Hypercholesterolemia is a risk factor for AD that might result in neurotoxicity and cognitive impairment. Dysfunction of lipoprotein and heme metabolism might also provide additional targets for AD diagnosis. Geriatr Gerontol Int 2017; 17: 1737-1745. © 2016 Japan Geriatrics Society.

  14. Influence of different implant materials on the primary stability of orthodontic mini-implants

    OpenAIRE

    Chin-Yun Pan; Szu-Ting Chou; Yu-Chuan Tseng; Yi-Hsin Yang; Chao-Yi Wu; Ting-Hsun Lan; Pao-Hsin Liu; Hong-Po Chang

    2012-01-01

    This study evaluates the influence of different implant materials on the primary stability of orthodontic mini-implants by measuring the resonance frequency. Twenty-five orthodontic mini-implants with a diameter of 2 mm were used. The first group contained stainless steel mini-implants with two different lengths (10 and 12 mm). The second group included titanium alloy mini-implants with two different lengths (10 and 12 mm) and stainless steel mini-implants 10 mm in length. The mini-implants w...

  15. Concerning production and decay of mini black holes

    CERN Document Server

    Hajdukovic, D

    2007-01-01

    In the next few years, theories predicting possibility to create mini black holes will be tested at CERN. Either experimental verification or rejection of these theories is of great scientific importance. There is a large consensus that, if successfully created, these short living mini black holes will decay through thermal (Hawking's) radiation. In the present comment we point out, that under assumption of the gravitational repulsion between matter and antimatter (in short we call it antigravity), thermal radiation may be dominated by a non-thermal radiation (being the consequence of pair creation from the vacuum, by gravitational field, which in the case of antigravity, pushes particles and antiparticles in opposite directions). Thus, the eventual creation of mini black holes may turn to be an unexpected opportunity to test the existence of antigravity.

  16. Late time CMB anisotropies constrain mini-charged particles

    Energy Technology Data Exchange (ETDEWEB)

    Burrage, C.; Redondo, J.; Ringwald, A. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Jaeckel, J. [Univ. of Durham, Inst. for Particle Physics Phenomenology (United Kingdom)

    2009-09-15

    Observations of the temperature anisotropies induced as light from the CMB passes through large scale structures in the late universe are a sensitive probe of the interactions of photons in such environments. In extensions of the Standard Model which give rise to mini-charged particles, photons propagating through transverse magnetic fields can be lost to pair production of such particles. Such a decrement in the photon flux would occur as photons from the CMB traverse the magnetic fields of galaxy clusters. Therefore late time CMB anisotropies can be used to constrain the properties of mini- charged particles. We outline how this test is constructed, and present new constraints on mini-charged particles from observations of the Sunyaev-Zel'dovich effect in the Coma cluster. (orig.)

  17. A mini-microscope for in situ monitoring of cells.

    Science.gov (United States)

    Kim, Sang Bok; Koo, Kyo-in; Bae, Hojae; Dokmeci, Mehmet R; Hamilton, Geraldine A; Bahinski, Anthony; Kim, Sun Min; Ingber, Donald E; Khademhosseini, Ali

    2012-10-21

    A mini-microscope was developed for in situ monitoring of cells by modifying off-the-shelf components of a commercial webcam. The mini-microscope consists of a CMOS imaging module, a small plastic lens and a white LED illumination source. The CMOS imaging module was connected to a laptop computer through a USB port for image acquisition and analysis. Due to its compact size, 8 × 10 × 9 cm, the present microscope is portable and can easily fit inside a conventional incubator, and enables real-time monitoring of cellular behaviour. Moreover, the mini-microscope can be used for imaging cells in conventional cell culture flasks, such as Petri dishes and multi-well plates. To demonstrate the operation of the mini-microscope, we monitored the cellular migration of mouse 3T3 fibroblasts in a scratch assay in medium containing three different concentrations of fetal bovine serum (5, 10, and 20%) and demonstrated differential responses depending on serum levels. In addition, we seeded embryonic stem cells inside poly(ethylene glycol) microwells and monitored the formation of stem cell aggregates in real time using the mini-microscope. Furthermore, we also combined a lab-on-a-chip microfluidic device for microdroplet generation and analysis with the mini-microscope and observed the formation of droplets under different flow conditions. Given its cost effectiveness, robust imaging and portability, the presented platform may be useful for a range of applications for real-time cellular imaging using lab-on-a-chip devices at low cost.

  18. Complete overdentures retained by mini implants: A systematic review.

    Science.gov (United States)

    Lemos, Cleidiel Aparecido Araujo; Verri, Fellippo Ramos; Batista, Victor Eduardo de Souza; Júnior, Joel Ferreira Santiago; Mello, Caroline Cantieri; Pellizzer, Eduardo Piza

    2017-02-01

    The purpose of this systematic review was to evaluate the use of mini implants to retain complete overdentures in terms of survival rates of mini implants, marginal bone loss, satisfaction, and quality of life. This report followed the PRISMA Statement and PICO question. This review has been registered at PROSPERO under the number CRD42016036141. Two independent reviewers performed a comprehensive search of studies published until September 2016 and listed in the PubMed/MEDLINE, Embase, and The Cochrane Library databases. The focused question was: is the use of mini implants feasible for prosthodontic rehabilitation with complete overdentures? The 24 studies selected for review evaluated 1273 patients whose mean age was 65.93 years; these patients had received 2494 mini implants and 386 standard implants for retaining overdenture prosthesis. The mean follow-up time was 2.48 years (range: 1-7 years). There was a higher survival rate of mini implants (92.32%). More frequent failures for maxillary (31.71%) compared with mandibular arches (4.89%). The majority of studies revealed marginal bone loss values similar to those of standard implants (overdenture prosthesis is considered an alternative treatment when standard treatment is not possible, since it presents high survival rates, acceptable marginal bone loss, and improvements in variables related to satisfaction and quality of life. Based on the results of this study, the use of a minimum 4 and 6 mini implants can be considered a satisfactory treatment option for rehabilitation of the mandibular and maxillary arches respectively with a complete overdenture. Copyright © 2016. Published by Elsevier Ltd.

  19. MAT FOR LEPTOSPIROSIS DIAGNOSIS

    Directory of Open Access Journals (Sweden)

    Esti Rahardianingtyas.

    2014-06-01

    Full Text Available Leptospirosis is a disease caused by bacterial infection leptospira interrogans.Leptospira bacteria is a spiral bacterium with solid strands with two flagella periplasmik.Septicaemic phase patient samples taken from the blood and cerebrospinal fluid, whereassamples taken at phase immune extracted from urine. The diagnosis of leptospirosis occurdirectly or indirectly. Diagnosis is done by directly isolate and identify the causative agents ofthe agent. Diagnosis is done indirectly by detecting specific antibodies from the patient's body.Gold Standard of the diagnosis of leptospirosis is MAT. Mat made by reacting antibodies toleptospira antigen. Positive results seen with clump formed.Key words: Leptospirosis, Leptospirosis Diagnostic, MAT (Microscopic Agglutination Test Leptospirosis merupakan penyakit yang disebabkan karena infeksi bakteri leptospirainterrogans. Bakteri leptospira merupakan bakteri spiral dengan untaian yang padat dengan duaflagella periplasmik. Sampel pasien pada fase septicaemic diambil dari darah dan cairanserebrospinal, sedangkan sampel yang diambil pada fase immune diambil dari urine. Diagnosisleptospirosis dilakukan secara langsung maupun tidak langsung. Diagnosis secara langsungdilakukan dengan cara mengisolasi agen penyebab dan mengidentifikasi agen tersebut. Diagnosissecara tidak langsung dilakukan dengan cara mendeteksi antibodi spesiflk dari dalam tubuhpasien. Gold Standart dari diagnosis leptospirosis adalah MAT. Mat dilakukan dengan caramereaksikan antibodi dengan antigen leptospira. Hasil positif dilihat dengan terbentuk gumpalanagglutinasiKata kunci: Leptospirosis, Leptospira, Leptospirosis Diagnosis.

  20. Humanities mini-course curricula for midcareer health professionals at the Penn State Milton S. Hershey Medical Center.

    Science.gov (United States)

    Myers, Kimberly R; George, Daniel R

    2012-08-01

    The field of medical humanities has traditionally focused on medical students and, more recently, on premedical undergraduates. Comparatively little formal humanities pedagogy has been dedicated to midcareer health professionals. To address this lack, the Department of Humanities at the Pennsylvania State University College of Medicine and the Milton S. Hershey Medical Center designed eight annual humanities mini-courses for faculty and staff throughout the college and medical center.These mini-courses fell into four categories: reading, reflection, and discussion; creative expression; technology; and ethics. They were geared toward midcareer health professionals who were seeking new intellectual and creative stimulation and variety in daily routine. They also provided humanities faculty the opportunity to devote attention to topics that capitalize on their professional training and that interest them personally.Participants indicated a high degree of satisfaction with the mini-courses for four principal reasons: (1) learning the tools and methodologies of a new discipline or domain other than biomedicine, (2) using their minds and training in uncustomary ways, (3) forming new alliances with colleagues (which served to lessen the sense of professional isolation), and (4) enjoying a respite from the stressful flow of the workday. Humanities faculty facilitators provided more mixed responses but agreed that conducting the mini-courses had been a positive overall experience.Although this article provides a foundational framework for the development of a humanities mini-course series, the authors encourage others to replicate these curricula in other medical settings as an important step toward a robust pedagogy designed for midcareer health care professionals.

  1. Towards the theory of mini black holes with subplanckian mass

    International Nuclear Information System (INIS)

    Zeldovich, Y.B.

    1984-01-01

    This chapter phenomenologically examines the question of the decay (evaporation) and formation of mini black holes. Neutral black holes are considered, having neither electrical charge, nor color and weak charge, so that no long range vector field is present beyond gravitational radius. Topics considered include thermodynamic equilibrium and the formation of light black holes, the formation and decay of light black holes in the big bang, and the difficulties of the theory. It is emphasized that the existence of mini black holes has not yet been proven

  2. Model of competitive mini-hotel project life cycle

    OpenAIRE

    Левыкин, Виктор Макарович; Дэвон, Валерия Викторовна

    2014-01-01

    Having examined the situation in the hotel market of the city of Kharkov (Ukraine), it was found that one of the major shortcomings in the activities of mini-hotels is mediocre attitude towards customers, lack of proper attention and poor services. In this regard, there is the need to create a mini-hotel, the most important mission of which would be a genuine concern for guests and their comfort, as well as providing unique services of the highest class.For the success of this mission, it is ...

  3. Accelerated Tooth Movement with Orthodontic Mini-Screws

    Directory of Open Access Journals (Sweden)

    S. Aksakalli

    2017-01-01

    Full Text Available This case report outlines the possibility of accelerated tooth movement with the combination of microosteoperforation and mini-screws. A 14-year-old male patient presented Class II malocclusion with maxillary incisor protrusion. Upper first premolars were extracted, and after leveling, accelerated canine distalization started. For pre- and postdistalization times, amount of distalization, periodontal health, and root resorption were assessed. Within the limitations of this case report, micro-osteoperforations with mini-screw have a potential for shortening the treatment time.

  4. High-flying Mini-Sniffer RPV - Mars bound

    Science.gov (United States)

    Reed, R. D.

    1978-01-01

    The Mini-Sniffer is a small unmanned survey aircraft developed by NASA to conduct turbulence and atmospheric pollution measurements from ground level to an altitude of 90,000 ft. Carrying a 25-lb air sampling apparatus, the Mini-Sniffer typically cruises for one hour at 70,000 ft before being remotely piloted back to earth. A hydrazine monopropellant engine powers the craft, while a PCM telemetering system and a radar transponder provide control functions. Development of a high-performance low-Reynolds-number airfoil could make the research craft suitable for a low-altitude terrain-following mission on Mars.

  5. The use of mini-samples in palaeomagnetism

    Science.gov (United States)

    Böhnel, Harald; Michalk, Daniel; Nowaczyk, Norbert; Naranjo, Gildardo Gonzalez

    2009-10-01

    Rock cores of ~25 mm diameter are widely used in palaeomagnetism. Occasionally smaller diameters have been used as well which represents distinct advantages in terms of throughput, weight of equipment and core collections. How their orientation precision compares to 25 mm cores, however, has not been evaluated in detail before. Here we compare the site mean directions and their statistical parameters for 12 lava flows sampled with 25 mm cores (standard samples, typically 8 cores per site) and with 12 mm drill cores (mini-samples, typically 14 cores per site). The site-mean directions for both sample sizes appear to be indistinguishable in most cases. For the mini-samples, site dispersion parameters k on average are slightly lower than for the standard samples reflecting their larger orienting and measurement errors. Applying the Wilcoxon signed-rank test the probability that k or α95 have the same distribution for both sizes is acceptable only at the 17.4 or 66.3 per cent level, respectively. The larger mini-core numbers per site appears to outweigh the lower k values yielding also slightly smaller confidence limits α95. Further, both k and α95 are less variable for mini-samples than for standard size samples. This is interpreted also to result from the larger number of mini-samples per site, which better averages out the detrimental effect of undetected abnormal remanence directions. Sampling of volcanic rocks with mini-samples therefore does not present a disadvantage in terms of the overall obtainable uncertainty of site mean directions. Apart from this, mini-samples do present clear advantages during the field work, as about twice the number of drill cores can be recovered compared to 25 mm cores, and the sampled rock unit is then more widely covered, which reduces the contribution of natural random errors produced, for example, by fractures, cooling joints, and palaeofield inhomogeneities. Mini-samples may be processed faster in the laboratory, which is of

  6. Lexicography Problems and Theoretical Interpretation of Mini-Dictionaries

    Directory of Open Access Journals (Sweden)

    Jūratė Butkienė

    2011-04-01

    Full Text Available The article deals with principles of the word selection while compiling a mini-dictionary (containing a minimal number of words as well as with criteria and theoretical background thereof. The development of such principles is being analysed in Lithuania and abroad. The word selection while compiling a mini-dictionary of German language dedicated to the students of Civil engineering is being detailed. Furthermore, the article provides recommendations. The word selection has to be based on the linguistic statistics and on the thorough text analysis.

  7. Mini-open vacuum-assisted closure therapy with instillation for debilitated and septic patients with pleural empyema.

    Science.gov (United States)

    Sziklavari, Zsolt; Ried, Michael; Neu, Reiner; Schemm, Rudolf; Grosser, Christian; Szöke, Tamas; Hofmann, Hans-Stefan

    2015-08-01

    This prospective study is an evaluation of the mini-open vacuum-assisted closure with instillation (Mini-VAC-Instill) therapy for the treatment of complicated pleural empyema. We investigated septic patients in poor general physical condition (Karnofsky index ≤50%) with multimorbidity and/or immunosuppression who were treated by minimally invasive intrathoracic VAC-Instill therapy without the insertion of an open-window thoracostomy (OWT) between December 2012 and November 2014. All patients underwent mini-thoracotomy with position of a tissue retractor, surgical debridement and local decortication. Surgery was followed by intrathoracic vacuum therapy including periodic instillation using antiseptics. The VAC dressings were changed under general anaesthesia and the chest wall was closed during the same hospital stay. All patients received systemic antibiotic therapy. Fifteen patients (13 males, median age: 71 years) underwent intrathoracic Mini-VAC-Instill dressings for the management of pleural empyema without bronchopleural fistula. The median length of vacuum therapy was 9 days (5-25 days) and the median number of VAC changes per patient was 1 (1-5). In-hospital mortality was 6.7% (n = 1) and was not related to Mini-VAC-Instill therapy or intrathoracic infection. Control of intrathoracic infection and closure of the chest cavity was achieved in 85.7% of surviving patients (12 of 14). After the follow-up at an average of 13.2 months (range, 3-25 months), we observed recurrence once, 21 days after discharge. Two patients died in the late postoperative period (Day 43 and Day 100 after discharge) of fulminant urosepsis and carcinoma-related multiorgan failure, respectively. Analysis of the follow-up interviews in the outpatient clinic showed a good quality of life and a subjectively good long-term aesthetic result. Mini-VAC-Instill therapy is an upgrade of Mini-VAC, which guarantees the advantage of an open treatment, including flushing but without OWT. This

  8. SOFC mini-tubulares basadas en YSZ

    Directory of Open Access Journals (Sweden)

    Campana, R.

    2008-08-01

    Full Text Available Tubular SOFC have the advantage over planar SOFC of the low temperature sealing and more resistance to thermal shock. On the other hand the volumetric power density of tubular Fuel Cells goes with the inverse of the tube diameter which added to the faster warm-up kinetics makes low diameter tubular SOFC favorable for low power applications. Anode supported tubular SOFC of 3mm diameter and 150 mm length with YSZ electrolyte were fabricated and tested by V-I measurements using H2-Ar (5, 10, 100 vol% as fuel and air for the cathode. The NiO-YSZ tubes of about 400 μm thickness were produced by hydrostatic pressure and then coated with an YSZ film of 15-20 μm. The electrolyte was deposited using a manual aerograph. After sintering either Pt paste or LSF (with YSZ or SDC coatings of about 20-50 μm thickness were deposited for the cathode. The OCV of the cells were excellent, very close to the expected Nernst law prediction indicating that there were not gas leaks. The maximun electrical power of the cell was near to 500mW/cm2 at 850ºC operation temperature. Complex impedance measurements of the cells were performed in order to determine the resistance of the different cell components.

    La principal ventaja de las SOFC tubulares frente a las planares es el sellado de la cámara anódica y catódica a bajas temperaturas. Además la densidad de energía volumétrica de las pilas tubulares es inversamente proporcional al diámetro del tubo, que añadido a los tiempos cortos de encendido y apagado hacen que las mini-tubulares sean interesantes para usos de baja potencia. Se han fabricado y caracterizado SOFC tubulares soportadas en ánodo de 3mm de diámetro y de 150 mm de longitud, 400μm de espesor, con electrolito de YSZ depositado por spray de 15-20 μm. Los tubos de NiO-YSZ son producidos por prensado isostático. La caracterización eléctrica se ha realizado empleando H2-Ar como combustible an

  9. Anthrax: Diagnosis

    Science.gov (United States)

    ... Diagnosis Language: English (US) Español (Spanish) Recommend on Facebook Tweet Share Compartir Doctors in the United States rarely see a patient with anthrax. CDC Guidance and case definitions are available to help doctors diagnose anthrax, take ...

  10. [Performance of an abbreviated mini mental examination to detect dementia in older people].

    Science.gov (United States)

    Jiménez, Daniel; Lavados, Manuel; Rojas, Paula; Henríquez, Claudio; Silva, Fernando; Guillón, Marta

    2017-07-01

    The usefulness of the abbreviated Mini-Mental State Examination included in the Chilean Functional assessment of elderly people (MM-SE-EFAM) to detect Dementia has not been determined. To assess the performance of the MMSE-EFAM to detect dementia. We studied a non-probabilistic sample of subjects older than 65 years who had been assessed by the MMSE-EFAM in a Chilean primary care center during a period of 6 months. Patients underwent clinical evaluation by a neurologist blinded to MMSE-EFAM score, to establish the diagnosis of dementia using DSM-IV-TR criteria. Besides, the full Mini-Mental State Examination (MMSE) was applied. The clinical diagnosis of Dementia was established in 13 of the 54 peoples evaluated. MMSE-EFAM had a sensitivity of 30.8% (95% confidence intervals (CI); 9-61.4) and a specificity of 90.2% (95% CI; 76.9%-97.3%), while MMSE had a sensitivity of 84.6% (95% CI; 54.6-98.1) and a specificity of 58.5% (95% CI; 42.1-73.7). In a receiver operating characteristic (ROC) curve analysis, the areas under the curve (AUC) were 0.77 (95% CI; 0.61-0.93) and 0.82 (95% CI; 0.70-0.95) for MMSE-EFAM and MMSE, respectively. Socio-demographic variables did not influence test performance in both cases. MMSE-EFAM has a low sensitivity to detect patients with Dementia and it is not an effective screening tool. These results are in agreement with the evidence and international guidelines that do not support the use of cognitive screening tools to detect dementia in the older general population.

  11. Psychometric evaluation of a Dutch version of the Mini PAS-ADD for assessing psychiatric disorders in adults with different levels of intellectual disability

    OpenAIRE

    Janssen, Rianne; Maes, Bea

    2013-01-01

    Background People with intellectual disabilities (ID) have an increased vulnerability to develop psychiatric problems. Moreover, the early recognition and the accurate diagnosis of psychiatric disorders in the population of persons with ID are challenging. Method A Dutch version of the Mini PAS-ADD, which is a screening instrument for identification of mental health problems in people with ID, was evaluated in terms of internal consistency, interinformant reliability, item grouping and ...

  12. Elevated Radiation Exposure Associated With Above Surface Flat Detector Mini C-Arm Use.

    Science.gov (United States)

    Martin, Dennis P; Chapman, Talia; Williamson, Christopher; Tinsley, Brian; Ilyas, Asif M; Wang, Mark L

    2017-11-01

    This study aims to test the hypothesis that: (1) radiation exposure is increased with the intended use of Flat Surface Image Intensifier (FSII) units above the operative surface compared with the traditional below-table configuration; (2) this differential increases in a dose-dependent manner; and (3) radiation exposure varies with body part and proximity to the radiation source. A surgeon mannequin was seated at a radiolucent hand table, positioned for volar distal radius plating. Thermoluminescent dosimeters measured exposure to the eyes, thyroid, chest, hand, and groin, for 1- and 15-minute trials from a mini C-arm FSII unit positioned above and below the operating surface. Background radiation was measured by control dosimeters placed within the operating theater. At 1-minute of exposure, hand and eye dosages were significantly greater with the flat detector positioned above the table. At 15-minutes of exposure, hand radiation dosage exceeded that of all other anatomic sites with the FSII in both positions. Hand exposure was increased in a dose-dependent manner with the flat detector in either position, whereas groin exposure saw a dose-dependent only with the flat detector beneath the operating table. These findings suggest that the surgeon's hands and eyes may incur greater radiation exposure compared with other body parts, during routine mini C-arm FSII utilization in its intended position above the operating table. The clinical impact of these findings remains unclear, and future long-term radiation safety investigation is warranted. Surgeons should take precautions to protect critical body parts, particularly when using FSII technology above the operating with prolonged exposure time.

  13. Synthesis and stability test of radiogadolinium(III-DOTA-PAMAM G3.0-trastuzumab as SPECT-MRI molecular imaging agent for diagnosis of HER-2 positive breast cancer

    Directory of Open Access Journals (Sweden)

    Hardiani Rahmania

    2015-01-01

    Full Text Available Nonivasive diagnosis of cancer can be provided by molecular imaging using hybrid modality to obtain better sensitivity, specificity and depiction localization of the disease. In this study, we developed a new molecular imaging agent, radiogadolinium(III-DOTA-PAMAM G3.0-trastuzumab in the form of 147Gd-DOTA-PAMAM G3.0-trastuzumab, that can be both target-specific radiopharmaceutical in SPECT as well as targeted contrast agent in MRI for the purpose of diagnosis of HER-2 positive breast cancer. 147Gd radionuclide emits γ-rays that can be used in SPECT modality, but because of technical constraint, 147Gd radionuclide was simulated by its radioisotope, 153Gd. Gd-DOTA complex has also been known as good MRI contrast agent. PAMAM G3.0 is useful to concentrate Gd-DOTA compelexes in large quantities, thus minimizing the number of trastuzumab molecules used. Trastuzumab is human monoclonal antibody that can spesifically interact with HER-2. Synthesis of radiogadolinium(III-DOTA-PAMAM G3.0-trastuzumab was initiated by conjugating DOTA NHS ester ligand with PAMAM G3.0 dendrimer. The DOTA-PAMAM G3.0 produced was conjugated to trastuzumab molecule and labeled with 153Gd. Characterization DOTA-PAMAM G3.0-trastuzumab immunoconjugate was performed using HPLC system equipped with SEC. The formation of immunoconjugate was indicated by the shorter retention time (6.82 min compared to that of trastuzumab (7.06 min. Radiochemical purity of radiogadolinium(III-DOTA-PAMAM G3.0-trastuzumab was >99% after purification process by PD-10 desalting column. Radiogadolinium(III-DOTA-PAMAM G3.0-trastuzumab compound was stable at room temperature and at 2–8 0C as indicated by its radiochemical purity 97.6 ± 0.5%–99.1 ± 0.5% after 144 h storage.

  14. Cerebral perfusion imaging in HIV positive patients

    International Nuclear Information System (INIS)

    Kundley, Kshama; Chowdhury, D.; Lele, V.R.; Lele, R.D.

    1998-01-01

    Full text: Twelve human immunodeficiency virus (HIV) positive patients were studied by SPECT cerebral perfusion imaging 1 hour post injection of 15 mCi of 99m Tc-ECD under ideal conditions with a triple head gamma camera (Prism 3000 X P LEUHR), fanbeam collimators followed by Folstein Mini Mental Status Examination (FMMSE) and AIDS dementia complex (ADC) staging on the same day. All 12 patients were male, in the age range of 23-45 y (mean 31 y). The infected status was diagnosed by ELISA (10 patients) or Western blot (5 patients). The interval between diagnosis and imaging ranged from 1 month - 35 months (mean 15.3 months). Two patients were alcoholic and 2 were smokers. None of them had CNS disorder clinically. ADC staging and FMMSE could be performed in 4 patients. Two patients were normal (stage 0) and 2 were subclinical (stage 0.5) on ADC staging. FMMSE revealed normal or near normal status (mean score 35; maximum score 36). Cerebral perfusion images were interpreted simultaneously by 3 observers blind towards history and examination using semi-quantitative and quantitative methods by consensus. It revealed multiple areas of hypoperfusion, viz. temporal (11 patients (91 %), parietal 10 patients (83%), frontal 9 patients (75%, pre and post central gyrus 7 patients (58%), occipital 6 patients (50%) cingulate gyrus and cerebellum 5 patients (41%) and thalamic in 2 patients (16%). Hyper perfusion in caudate nuclei was noted in 10 patients (83%). The study reveals presence of multiple perfusion abnormalities on cerebral perfusion imaging in HIV positive patients who have normal/near normal mental status suggesting precedence of perfusion abnormality over clinically apparent mental deficit

  15. Presence of dual diagnosis between users and non-users of licit and illicit drugs in Brazil

    OpenAIRE

    Formiga,Mariana Bandeira; Vasconcelos,Selene Cordeiro; Galdino,Melyssa Kellyane Cavalcanti; Lima,Murilo Duarte da Costa

    2015-01-01

    ABSTRACT Objective Investigate the occurrence of dual diagnosis in users of legal and illegal drugs. Methods It is an analytical, cross-sectional study with a quantitative approach, non-probabilistic intentional sampling, carried out in two centers for drug addiction treatment, by means of individual interviews. A sociodemographic questionnaire, the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) and the Mini-International Neuropsychiatric Interview (MINI) were used. R...

  16. Mini soap operas foster financial education and inclusion of women ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-05-04

    May 4, 2016 ... Mini soap operas foster financial education and inclusion of women in Peru ... they are less vulnerable to external shocks and can invest in health, education, ... was launched to encourage saving among women who received benefits under ... Evaluating vocational training program for women in Brazil.

  17. Mini-Enterprise Projects: Friendship, Business and Learning

    Science.gov (United States)

    Riese, Hanne

    2013-01-01

    This article discusses how the mini-enterprise (ME) approach (Young Enterprise) can be understood as a tool for helping to achieve policy goals set for entrepreneurship. Analysis of 12 semi-structured interviews with 17-year-old students shows how social capital from friendship relations constitutes norms for interaction in MEs. To some extent,…

  18. Are mini DNA-barcodes sufficiently informative to resolve species ...

    Indian Academy of Sciences (India)

    ... between mini-barcode and the full- length DNA barcode was carried out in Microsoft Excel. (http://www.office.microsoft.com). ..... Received 15 June 2013, in final revised form 5 April 2014; accepted 3 June 2014. Unedited version published ...

  19. A magnetic-lens - mini-orange coincidence spectrometer

    International Nuclear Information System (INIS)

    Bargholtz, C.; Holmberg, L.; Ruus, N.; Tegner, P.E.; Weiss, G.

    1997-04-01

    A coincidence spectrometer consisting of a Gerholm type magnetic lens and a permanent magnet mini-orange spectrometer is described. Electron-electron or electron-positron coincidences may be registered in various angular settings. The spectrometer has been developed mainly to search for anomalous contributions to Bhabha scattering or positrons and is at present used for such studies. 6 refs

  20. Water Boiler Change-Over in Mini-TPP Mode

    Directory of Open Access Journals (Sweden)

    B. A. Bayrashevsky

    2011-01-01

    Full Text Available The paper considers water boiler modernization by its change-over in mini-TPP mode with an expansion tank and a heating turbine of small capacity.  A software complex permitting to evaluate competitive ability of such water boiler modernization in comparison with a cogeneration plant.

  1. Cooling down MiniGRAIL to milli-Kelvin temperatures

    NARCIS (Netherlands)

    de Waard, A.; de Waard, A.; Gottardi, L.; Bassan, M.; Coccia, E.; Fafone, V.; Flokstra, Jakob; Karbalai-Sadegh, A.; Minenkov, Y.; Moleti, A.; Pallottino, G.V.; Podt, M.; Pors, B.J.; Reincke, W; Rocchi, A.; Shumack, A.; Srinivas, S.; Visco, M.; Frossati, G.

    2004-01-01

    The latest developments in the construction of the ultra-cryogenic spherical detector MiniGRAIL are presented. The room temperature part of the vibration isolation system was improved and provided with an attenuation of about 60 dB around 3 kHz. The transfer function of the cryogenic stages gave

  2. Mini Games for Professional Awareness in Introductory Psychology

    NARCIS (Netherlands)

    Hummel, Hans; Nadolski, Rob; Eshuis, Jannes; Slootmaker, Aad

    2017-01-01

    Main problems with the current course Introduction to Psychology in our university is that students consider the content as too theoretical and insufficient in providing professional practice. Potential solutions are expected to come from mini-games that have proven to enable more active and

  3. Vacuum design for a superconducting mini-collider

    International Nuclear Information System (INIS)

    Barletta, W.A.; Monteiro, S.

    1991-01-01

    The phi factory (Superconducting Mini-Collider or SMC) proposed for construction at UCLA is a single storage ring with circulating currents of 2 A each of electrons and positrons. The small circumference exacerbates the difficulties of handling the gas load due to photodesorption from the chamber walls. The authors analyze the vacuum system for the phi factory to specify design choices

  4. Rational Design of Mini-Cas9 for Transcriptional Activation.

    Science.gov (United States)

    Ma, Dacheng; Peng, Shuguang; Huang, Weiren; Cai, Zhiming; Xie, Zhen

    2018-04-20

    Nuclease dead Cas9 (dCas9) has been widely used for modulating gene expression by fusing with different activation or repression domains. However, delivery of the CRISPR/Cas system fused with various effector domains in a single adeno-associated virus (AAV) remains challenging due to the payload limit. Here, we engineered a set of downsized variants of Cas9 including Staphylococcus aureus Cas9 (SaCas9) that retained DNA binding activity by deleting conserved functional domains. We demonstrated that fusing FokI nuclease domain to the N-terminal of the minimal SaCas9 (mini-SaCas9) or to the middle of the split mini-SaCas9 can trigger efficient DNA cleavage. In addition, we constructed a set of compact transactivation domains based on the tripartite VPR activation domain and self-assembled arrays of split SpyTag:SpyCatch peptides, which are suitable for fusing to the mini-SaCas9. Lastly, we produced a single AAV containing the mini-SaCas9 fused with a downsized transactivation domain along with an optimized gRNA expression cassette, which showed efficient transactivation activity. Our results highlighted a practical approach to generate down-sized CRISPR/Cas9 and gene activation systems for in vivo applications.

  5. From Rindler horizon to mini black holes at LHC

    Energy Technology Data Exchange (ETDEWEB)

    Ghaffary, Tooraj [Islamic Azad University, Department of Science, Shiraz Branch, Shiraz (Iran, Islamic Republic of)

    2017-02-15

    Recently researchers (A. Sepehri et al., Astrophys. Space Sci. 344, 79 (2013)) have considered the signature of superstring balls near mini black holes at LHC and calculate the information loss for these types of strings. Motivated by their work, we consider the evolution of events in high energy experiments from lower energies for which the Rindler horizon is formed to higher energies in which mini black holes and string balls are emerged. Extending the Gottesman and Preskill method to string theory, we find the information loss for excited strings ''string balls'' in mini black holes at LHC and calculate the information transformation from the collapsing matter to the state of outgoing Hawking radiation for strings. We come to the conclusion that information transformation for high energy strings is complete. Then the thermal distribution of excited strings near mini black holes at LHC is calculated. In order to obtain the total string cross section near black holes produced in proton-proton collision, we multiply the black hole production cross section by the thermal distribution of strings. It is observed that many high energy excited strings are produced near the event horizon of TeV black holes. These excited strings evaporate to standard model particles like Higgs boson and top quark at Hagedorn temperature. We derive the production cross section for these particles due to string ball decay at LHC and consider their decay to light particles like bottom quarks and gluons. (orig.)

  6. Experience in small hydropower indigenous manufacture of mini hydraulic turbines

    Energy Technology Data Exchange (ETDEWEB)

    Luo Gao Rong [Organization of the United Nations, Beijing (China). International Centre of Small Hydropowers

    1995-07-01

    This document reports the China experience with fabrication of mini hydraulic turbines for small hydroelectric power plants. The document presents the necessity of indigenous manufacture for MHP equipment, the standardized and serialized production, the planning of the series of turbines, the manufacturing of turbine runners, and as a case study the basic conditions for manufacturing MHP turbines.

  7. Model Pemberdayaan Laboratorium Bank Mini Syariah di Perguruan Tinggi

    Directory of Open Access Journals (Sweden)

    Eva Fauziah

    2018-03-01

    results showed that the model of empowerment of Mini Sharia Bank laboratory in Higher Education has four models; they are 1 model of secondary empowerment, 2 model primary internal empowerment of student, 3 model of primary internal empowerment of student and lecturer and 4 model of primary external empowerment. This laboratory empowerment model is based on observations at four universities in Java, namely Bandung Islamic University (UNISBA, Islamic University of Malang (UNISMA, UIN Malang and UIN Sunan Ampel Surabaya. Laboratorium Bank Mini Syariah merupakan sarana penunjang dan pelaksana program Tri Dharma Perguruan Tinggi yang diharapkan mampu memberikan kontribusi untuk mengakselerasi perkembangan syariah di Indonesia. Oleh karena itu, pemberdayaan laboratorium Bank Mini Syariah sebagai tempat mengembangkan kompetensi baik dalam bidang intelektual, ketrampilan motorik dan terampil memggunakan alat-alat media perbankan syariah untuk peningkatan kompetensi mahasiswa lulusan keuangan dan perbankan syariah perlu ditelaah. Metode penelitian menggunakan metode kualitatif dengan teknik pengumpulan data observasi mendalam. Analisis data menggunakan analisis domain model spradley. Hasil penelitian menunjukkan bahwa model pemberdayaan laboratorium Bank Mini Syariah di Perguruan Tinggi memiliki empat model yaitu 1. Model pemberdayaan sekunder, 2. Model pemberdayaan primer internal mahasiswa, 3. Model pemberdayaan primer internal mahasiswa dan dosen, dan 4. Model pemberdayaan primer eksternal. Model pemberdayaan laboratorium ini berdasarkan pengamatan pada empat perguruan tinggi di Jawa yaitu Universitas Islam Bandung, Universitas Islam Malang, UIN Malang dan UIN Sunan Ampel Surabaya.

  8. Mini mental state examination. Validering af en ny dansk udgave

    DEFF Research Database (Denmark)

    Korner, E.A.; Lauritzen, L.; Nilsson, F.M.

    2008-01-01

    INTRODUCTION: The Mini Mental State Examination (MMSE) is widely used in Denmark, but often in non-validated versions. In 2000 a cross-sectional workgroup decided on a new common version of the MMSE with a corresponding manual, which is validated for the first time in the present study. MATERIALS...

  9. Psychometric Properties of the Folstein Mini-Mental State Examination

    Science.gov (United States)

    Lopez, Michael N.; Charter, Richard A.; Mostafavi, Beeta; Nibut, Lorraine P.; Smith, Whitney E.

    2005-01-01

    Criterion-referenced (Livingston) and norm-referenced (Gilmer-Feldt) techniques were used to measure the internal consistency reliability of Folsteins Mini-Mental State Examination (MMSE) on a large sample (N = 418) of elderly medical patients. Two administration and scoring variants of the MMSE Attention and Calculation section (Serial 7s only…

  10. Alzheimer's Dementia: Performance on the Mini-Mental State Examination.

    Science.gov (United States)

    Teng, Evelyn Lee; And Others

    1987-01-01

    Analyzed the performance of Alzheimer's patients (N=141) on the Mini-Mental State Examination. Performance on all items showed significant negative correlation with the duration of the illness. The most difficult item was "recall," and the improvement in recall was obtained with cuing. (Author/ABB)

  11. SQUID developments for the gravitational wave antenna MiniGRAIL

    NARCIS (Netherlands)

    Pleikies, J.; Usenko, O.; Kuit, K.H.; Flokstra, Jakob; de Waard, A.; de Waard, A.; Frossati, G.

    2007-01-01

    We designed two different sensor SQUIDs for the readout of the resonant mass gravitational wave detector MiniGRAIL. Both designs have integrated input inductors in the order of 1.5 muH and are planned for operation in the mK temperature range. Cooling fins were added to the shunt resistors. The

  12. Mini transverse versus longitudinal incision in carpal tunnel syndrome

    International Nuclear Information System (INIS)

    Korkmaz, M.; Cepoglu, M.C.

    2013-01-01

    Objective: To evaluate the effectiveness of mini-transverse compared with mini-longitudinal incision for carpal tunnel release (CTR) with reference to postoperative functional capacity, symptom severity and complication rate. Study Design: Analytical study. Place and Duration of Study: Cumhuriyet University Medical Faculty, Department of Orthopaedics, Tokat State Hospital, Department of Orthopaedics and Medical Park Tokat Hospital, Department of Neurosurgery, from January 2007 to January 2009. Methodology: This study included 93 hands of 79 patients with carpal tunnel syndrome (CTS), which were operated between 2007 and 2009. Patients were divided according to incision types into Group-1 (undergoing mini-longitudinal incision) and Group-2 (undergoing mini-transverse incision). Patients were evaluated initially and at 3 weeks after treatment according to symptom severity and functional status of Boston Questionnaire (BQ). Demographic and clinical data were analyzed and compared statistically between two groups. Results: Statistically significant differences were observed in BQ symptom and functional scores between the pre- and postoperative period (p < 0.0001). BQ symptom and functional scores at postoperative period were better in Group-1 than Group-2 (p = 0.044 and p = 0.023 respectively). The scar hypersensitivity (p = 0.258) and tenderness (p = 1.00) associated with the incision sites were not statistically different. Conclusion: Longitudinal incision is more effective on symptom and functional conditions than transverse incision. However, there was less scar formation with transverse incision. (author)

  13. Could mini black holes provide a 'theory of everything'?

    CERN Multimedia

    Gribbin, J

    1990-01-01

    A Soviet astrophysicist is claiming that the Earth and other astronomical bodies may be riddled with mini black holes - objects smaller than atoms but with masses perhaps greater than planets. These could be responsible for a variety of phenomena inc the rings of Saturn (1/2 page).

  14. [In vivo digestibility of rice genetically modified with CpTI in WZS mini-pig].

    Science.gov (United States)

    Huang, Qiong; Liu, Haibo; Zhi, Yuan; Gao, Peng; Yy, Zhou; Liu, Shan; Xu, Haibin

    2011-11-01

    To establish a stable in vivo gastrointestinal model of WZS mini-pig to evaluate the digestibility of rice genetically modified with CpTI (Cowpea Trypsin Inhibitor). METHODS; Three WZS mini-pigs were surgically fitted with O-stomach cannula and T-ileum cannula, and fed with soybean (positive control), CpTI rice and its parental rice meals. The pH value of gastric and intestinal fluid was monitored at different time points. The digested protein products were measured with protein gel electrophoresis at different time points. The pH value of gastric contents was rapidly neutralized by the meal to approximately 6.0, then the pH was reduced by HCl secretion,and it subsequently was increased after 4-6 hours. Compared with rice,the increase or decrease of pH after soybean being fed was later. Soybean protein segments 13kD,17kD, 34kD and 50kD could be highly detected in gastric and intestinal fluid at 5-6h after soybean being introduced. The segment 13kD was digested in intestine. However, no any protein segment was found in the gastric fluid 0.25h after rice being fed. There was no any difference in digestibility between the rice genetically modified with CpTI and its parental rice. It is practicable to establish a in vivo model of WZS mini-pig for digestibility. The digestibility of CpTI rice and its parental rice in gastric and intestinal tract in vivo is equivalent.

  15. Detection and eradication of Spongospora subterranea in mini-tuber production tunnels

    Directory of Open Access Journals (Sweden)

    Jacquie E. van der Waals

    2012-05-01

    Full Text Available Powdery scab, a root and tuber disease caused by the pathogen Spongospora subterranea f.sp. subterranea (Sss, poses a major problem to potato producers worldwide because it affects potato quality. Inoculum can be seed-borne or originate from contaminated growing media or contaminated equipment. During 2006, a potato mini-tuber production facility in Ceres in the Western Cape Province of South Africa had an outbreak of powdery scab. The purpose of this study was to detect Sss in the production facility and identify the source or sources of contamination so that corrective measures could be taken to eradicate the pathogen. Swab samples were taken from numerous points in the facility in 2009 and Sss-specific primers (Sps1 and Sps2 were used in a polymerase chain reaction to detect Sss. Of 11 surfaces tested, 6 were positive for Sss. A second set of swab samples was taken after efforts were made to eradicate the pathogen through improved facility hygiene measures to determine whether these corrective measures were efficient. Corrective measures resulted in a disease-free harvest from 2009 onwards. This novel study has value for the mini-tuber industry as production tunnels can be tested for the presence of Sss and other pathogens before planting to ensure that, where suitable control measures are available, disease-free mini-tubers are produced.

  16. Refining MARGINS Mini-Lessons Using Classroom Observations

    Science.gov (United States)

    Iverson, E. A.; Manduca, C. A.; McDaris, J. R.; Lee, S.

    2009-12-01

    One of the challenges that we face in developing teaching materials or activities from research findings is testing the materials to determine that they work as intended. Traditionally faculty develop material for their own class, notice what worked and didn’t, and improve them the next year. However, as we move to a community process of creating and sharing teaching materials, a community-based process for testing materials is appropriate. The MARGINS project has piloted such a process for testing teaching materials and activities developed as part of its mini-lesson project (http://serc.carleton.edu/margins/index.html). Building on prior work developing mechanisms for community review of teaching resources (e.g. Kastens, 2002; Hancock and Manduca, 2005; Mayhew and Hall, 2007), the MARGINS evaluation team developed a structured classroom observation protocol. The goals of field testing are to a) gather structured, consistent feedback for the lesson authors based on classroom use; b) guide reviewers of these lessons to reflect on research-based educational practice as a framework for their comments; c) collect information on the data and observations that the reviewer used to underpin their review; d) determine which mini-lessons are ready to be made widely available on the website. The protocol guides faculty observations on why they used the activity, the effectiveness of the activity in their classroom, the success of the activity in leading to the desired learning, and what other faculty need to successfully use the activity. Available online (http://serc.carleton.edu/margins/protocol.html), the protocol can be downloaded and completed during instruction with the activity. In order to encourage review of mini-lessons using the protocol, a workshop focused on review and revision of activities was held in May 2009. In preparation for the workshop, 13 of the 28 participants chose to field test a mini-lesson prior to the workshop and reported that they found this

  17. Mini implants for definitive prosthodontic treatment: a systematic review.

    Science.gov (United States)

    Bidra, Avinash S; Almas, Khalid

    2013-03-01

    Mini implants are commonly used in orthodontics and for interim prosthodontic treatment, but evidence for their use in definitive prosthodontic treatment is not clear. This systematic review evaluated the mini-implant literature to analyze short-term (1 to 5 years), medium-term (5 to 10 years), and long-term (beyond 10 years) survival rates when used for definitive prosthodontic treatment. An electronic search of the English language literature for articles published between January 1974 and May 2012 was performed by using PubMed and Cochrane databases with predetermined inclusion criteria. Key terms included in the search were mini dental implants, narrow diameter implants, reduced diameter implants, small diameter implants, transitional implants, interim implants, and provisional implants. After a systematic filtering process, the selected articles were subjected to a detailed review, and the data collected were used to calculate the 1-year interval survival rate (ISR) and the cumulative survival rate (CSR). The electronic database search yielded 1807 titles. By scrutinizing the titles and abstracts with inclusion and exclusion criteria, the researchers identified 9 studies of mini implants for definitive prosthodontic treatment. Of the studies identified, 1 was a randomized controlled trial, 2 were prospective studies, and 6 were retrospective studies. The majority of mini implants were placed by using a flapless surgical technique in the mandibular anterior region to support an overdenture. The 1st year ISR was 94.7% and the CSR over a 9-year period, primarily attributed to data from 1 study, was 92.2%. Most implants were immediately loaded and almost all implant failures occurred during the first year after implant placement. For short-term survival, the first year ISR of 94.7% of mini dental implants appears encouraging, but the true 1-year survival rate is unknown, as the minimum follow-up period reported for several implants was less than a year

  18. Mini-Sniffer III on Lakebed with Ground Support Crew

    Science.gov (United States)

    1976-01-01

    The third version of the Mini-Sniffer remotely-piloted research vehicle on Rogers Dry Lake, adjacent to NASA's Dryden Flight Research Center, Edwards, California. The futuristic-looking ground crew are in white, self-contained suits, because the engine on this third version of the Mini-Sniffer was powered by hydrazine, which is a very hazardous material. The Mini-Sniffer was a remotely controlled, propeller-driven vehicle developed at the NASA Flight Research Center (which became the Dryden Flight Research Center, Edwards, California, in 1976) as a potential platform to sample the upper atmosphere for pollution. The vehicle, flown from 1975 to 1977, was one of the earliest attempts by NASA to develop an aircraft that could sense turbulence and measure natural and human-produced atmospheric pollutants at altitudes above 80,000 feet with a variable-load propeller that was never flight-tested. Three Mini-Sniffer vehicles were built. The number 1 Mini-Sniffer vehicle had swept wings with a span of 18 feet and canards on the nose. It flew 12 flights with the gas-powered engine at low altitudes of around 2,500 feet. The number 1 vehicle was then modified into version number 2 by removing the canards and wing rudders and adding wing tips and tail booms. Twenty flights were made with this version, up to altitudes of 20,000 feet. The number 3 vehicle had a longer fuselage, was lighter in weight, and was powered by the non-air-breathing hydrazine engine designed by NASA's Johnson Space Center in Houston, Texas. This version was designed to fly a 25-pound payload to an altitude of 70,000 feet for one hour or to climb to 90,000 feet and glide back. The number 3 Mini-Sniffer made one flight to 20,000 feet and was not flown again because of a hydrazine leak problem. All three versions used a pusher propeller to free the nose area for an atmospheric-sampling payload. At various times the Mini-Sniffer has been considered for exploration in the carbon dioxide atmosphere of the

  19. Revisiting the stability of mini-implants used for orthodontic anchorage

    Directory of Open Access Journals (Sweden)

    Chung-Chen Jane Yao

    2015-11-01

    Conclusion: This study revealed that once the dental surgeon becomes familiar with the procedure, the stability of orthodontic mini-implants depends on the type of mini-implant, age of the patient, implantation site, and the healing time of the mini-implant. Miniplates are a more feasible anchorage system when miniscrews fail repeatedly.

  20. Replacing the AMOR with the miniDOAS in the ammonia monitoring network in the Netherlands

    NARCIS (Netherlands)

    Berkhout, Augustinus J. C.; Swart, Daan P. J.; Volten, Hester; Gast, Lou F. L.; Haaima, Marty; Verboom, Hans; Stefess, Guus; Hafkenscheid, Theo; Hoogerbrugge, Ronald

    2017-01-01

    In this paper we present the continued development of the miniDOAS, an active differential optical absorption spectroscopy (DOAS) instrument used to measure ammonia concentrations in ambient air. The miniDOAS has been adapted for use in the Dutch National Air Quality Monitoring Network. The miniDOAS

  1. A Validation Study of the Web Screening Questionnaire (WSQ) Compared With the Mini-International Neuropsychiatric Interview-Plus (MINI-Plus)

    Science.gov (United States)

    Giltay, Erik J; Carlier, Ingrid VE; van Vliet, Irene M; van Hemert, Albert M; Zitman, Frans G

    2017-01-01

    Background There is a need for brief screening methods for psychiatric disorders in clinical practice. This study assesses the validity and accuracy of a brief self-report screening questionnaire, the Web Screening Questionnaire (WSQ), in detecting psychiatric disorders in a study group comprising the general population and psychiatric outpatients aged 18 years and older. Objective The aim of this study was to investigate whether the WSQ is an adequate test to screen for the presence of depressive and anxiety disorders in clinical practice. Methods Participants were 1292 adults (1117 subjects from the general population and 175 psychiatric outpatients), aged 18 to 65 years. The discriminant characteristics of the WSQ were examined in relation to the (“gold standard”) Mini-International Neuropsychiatric Interview-Plus (MINI-Plus) disorders, by means of sensitivity, specificity, area under the curve (AUC), and positive and negative predictive values (PPVs, NPVs). Results The specificity of the WSQ to individually detect depressive disorders, anxiety disorders, and alcohol abuse or dependence ranged from 0.89 to 0.97 for most disorders, with the exception of post-traumatic stress disorder (0.52) and specific phobia (0.73). The sensitivity values ranged from 0.67 to 1.00, with the exception of depressive disorder (0.56) and alcohol abuse or dependence (0.56). Given the low prevalence of separate disorders in the general population sample, NPVs were extremely high across disorders (≥0.97), whereas PPVs were of poor strength (range 0.02-0.33). Conclusions In this study group, the WSQ was a relatively good screening tool to identify individuals without a depressive or anxiety disorder, as it accurately identified those unlikely to suffer from these disorders (except for post-traumatic stress disorders and specific phobias). However, in case of a positive WSQ screening result, further diagnostic procedures are required. PMID:28851674

  2. Fault diagnosis

    Science.gov (United States)

    Abbott, Kathy

    1990-01-01

    The objective of the research in this area of fault management is to develop and implement a decision aiding concept for diagnosing faults, especially faults which are difficult for pilots to identify, and to develop methods for presenting the diagnosis information to the flight crew in a timely and comprehensible manner. The requirements for the diagnosis concept were identified by interviewing pilots, analyzing actual incident and accident cases, and examining psychology literature on how humans perform diagnosis. The diagnosis decision aiding concept developed based on those requirements takes abnormal sensor readings as input, as identified by a fault monitor. Based on these abnormal sensor readings, the diagnosis concept identifies the cause or source of the fault and all components affected by the fault. This concept was implemented for diagnosis of aircraft propulsion and hydraulic subsystems in a computer program called Draphys (Diagnostic Reasoning About Physical Systems). Draphys is unique in two important ways. First, it uses models of both functional and physical relationships in the subsystems. Using both models enables the diagnostic reasoning to identify the fault propagation as the faulted system continues to operate, and to diagnose physical damage. Draphys also reasons about behavior of the faulted system over time, to eliminate possibilities as more information becomes available, and to update the system status as more components are affected by the fault. The crew interface research is examining display issues associated with presenting diagnosis information to the flight crew. One study examined issues for presenting system status information. One lesson learned from that study was that pilots found fault situations to be more complex if they involved multiple subsystems. Another was pilots could identify the faulted systems more quickly if the system status was presented in pictorial or text format. Another study is currently under way to

  3. Cryopreservation of boar semen in mini- and maxi-straws.

    Science.gov (United States)

    Bwanga, C O; de Braganca, M M; Einarsson, S; Rodriguez-Martinez, H

    1990-10-01

    Split ejaculates from four boars were frozen with a programmable freezing machine, in mini- (0.25 ml) and maxi- (5 ml) plastic straws with an extender at either acidic (6.3) or alkaline (7.4) pH. Glycerol (3%) was used as cryoprotectant. The freezing of the semen was monitored by way of thermocouples placed in the straws. Post-thaw motility and acrosome integrity were evaluated; the latter using phase contrast microscopy, eosin-nigrosin stain and electron microscopy. Post-thaw sperm motility was significantly higher when semen was frozen in mini-straws than in maxi-straws. For the mini-straws, the motility was better when semen was exposed to an acidic environment during freezing, but this beneficial effect of the low extracellular pH was not evident when maxi-straws were thawed. The motility of the spermatozoa diminished significantly during the thermoresistance test (0 h and 2 h time) at 37 degrees C in a similar way for both straws and extracellular pH's. The freezing procedure, no matter the extracellular pH, did not cause major acrosomal damages, but significantly more normal apical ridges were present in the mini-straws than in the maxi-straws. This in vitro evaluation indicated that the freezing method employed was better for mini- than for maxi-straws since the freezing of the 5 ml volumes was not homogeneous, due to the large section area between the surface and the core of the straw.

  4. Photovoltaic energy mini-generation: Future perspectives for Portugal

    International Nuclear Information System (INIS)

    Carvalho, Duarte; Wemans, Joao; Lima, Joao; Malico, Isabel

    2011-01-01

    This paper evaluates the benefits of developing the mini-generation PV market in Portugal. It presents the legal framework and current status of the Portuguese PV electricity sector, and compares the country to other European nations: France, Germany, Greece, Italy, Spain and the United Kingdom. A model that combines PVGIS with a self-developed financial tool is used to assess the feasibility of a 150 kW mini-generation system using five different technologies: fixed mount, single-axis tracking, double-axis tracking, low concentration and medium concentration (MCPV). The profitability of the mini-generation systems in the seven countries studied is calculated and compared. According to this analysis, MCPV and, of the conventional technologies, the single-axis tracking systems are the most profitable technologies. Despite the attractiveness of the current Portuguese feed-in tariffs and of the abundant solar resource, investors are discouraged and the country's PV market is far from mature. Specific mini-generation regulations should focus on a fast and transparent licensing procedure and should promote the access to financing. This would attract new investments, which would result in the growth of the PV electricity produced, and would help Portugal to meet its European Union Renewable Energy targets. - Highlights: → This work promotes the development of a mini-generation PV market in Portugal. → The Portuguese current status and legal framework is compared to other EU countries. → The profitability of 5 different PV technologies is compared for 7 European countries. → The Portuguese growth potential for PV energy is still big. → Portugal, due to its radiation levels, presents excellent investment opportunities.

  5. Prenatal Diagnosis

    Directory of Open Access Journals (Sweden)

    Ozge Ozalp Yuregir

    2012-02-01

    Full Text Available Prenatal diagnosis is the process of determining the health or disease status of the fetus or embryo before birth. The purpose is early detection of diseases and early intervention when required. Prenatal genetic tests comprise of cytogenetic (chromosome assessment and molecular (DNA mutation analysis tests. Prenatal testing enables the early diagnosis of many diseases in risky pregnancies. Furthermore, in the event of a disease, diagnosing prenatally will facilitate the planning of necessary precautions and treatments, both before and after birth. Upon prenatal diagnosis of some diseases, termination of the pregnancy could be possible according to the family's wishes and within the legal frameworks. [Archives Medical Review Journal 2012; 21(1.000: 80-94

  6. Validity of a short clinical interview for psychiatric diagnosis: the mini-SCAN.

    NARCIS (Netherlands)

    Kaptein, K.I.; Jonge, P. de; Korf, J.; Spijker, J.; Graaf, R. de; Werf, S.Y. van der

    2007-01-01

    Background. It has recently been proposed that major depression disorder (MDD) may, in a heterogeneous population-based cohort, be interpreted in terms of a random-mood model. Mood fluctuations are thought to result from stressors that occur randomly in time. We have investigated whether this

  7. Mini-clinical evaluation exercise til evaluering af kommunikation og samarbejde i ambulatoriet

    DEFF Research Database (Denmark)

    Eriksen, Jesper Grau; Simonsen, Dorit; Bastholt, Lars

    2009-01-01

    INTRODUCTION: In the revised Danish medical specialist training increased focus has been placed on competences which are hard to evaluate such as communication skills. Mini-CEX seems promising as an evaluation tool. Our aim was to test: 1) whether mini-CEX was useable in the evaluation...... of communicative and cooperative skills and 2) whether mini-CEX would provide reproducible data. MATERIAL AND METHODS: Twenty-one residents were evaluated by mini-CEX by trained observers. Seventeen residents had at least two observations within a short period of time and these data were used to estimate the mini...

  8. SARS - Diagnosis

    Indian Academy of Sciences (India)

    SARS - Diagnosis. Mainly by exclusion of known causes of atypical pneumonia; * X ray Chest; * PCR on body fluids- primers defined by WHO centres available from website.-ve result does not exclude SARS. * Sequencing of amplicons; * Viral Cultures – demanding; * Antibody tests.

  9. GeMini: The Next Generation Mechanically-Cooled Germanium Spectrometer

    International Nuclear Information System (INIS)

    Burks, M.

    2008-01-01

    The next-generation mechanically-cooled germanium spectrometer has been developed. GeMini (GErmanium MINIature spectrometer) has been designed to bring high-resolution gamma-ray spectroscopy to a range of demanding field environments. Intended applications include short-notice and surprise inspections where positive nuclide identification of radioactive materials is required. GeMini weighs 2.75 kg (6 lbs) total including the detector, cryostat, cryocooler, batteries, electronics and readout. It is very low power allowing it to operate for 10 hours on a single set of rechargeable batteries. This instrument employs technology adapted from the gamma-ray spectrometer currently flying on NASA's Mercury MESSENGER spacecraft. Specifically, infrared shielding techniques allow for a vast reduction of thermal load. This in turn allows for a smaller, lighter-weight design, well-suited for a hand-held instrument. Two working prototypes have been built and tested in the lab. The target energy resolution is 3 keV fwhm or better for 1332 keV gamma-rays. The detectors currently achieve around 4.5 keV resolution, which is slightly higher than our goal due to microphonic noise. Our present work focuses on improving the resolution through mechanical and electronic means of reducing the microphonic noise. This paper will focus on the performance of the instrument and its applicability for inspectors in the field

  10. GeMini: The Next-Generation Mechanically-Cooled Germanium Spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Burks, M

    2008-11-12

    The next-generation mechanically-cooled germanium spectrometer has been developed. GeMini (MINIature GErmanium spectrometer) has been designed to bring high-resolution gamma-ray spectroscopy to a range of demanding field environments. Intended applications include short-notice inspections, border patrol, port monitoring and emergency response, where positive nuclide identification of radioactive materials is required but power and liquid cryogen are not easily available. GeMini weighs 2.75 kg for the basic instrument and 4.5 kg for the full instrument including user interface and ruggedized hermetic packaging. It is very low power allowing it to operate for 10 hours on a single set of rechargeable batteries. This instrument employs technology adapted from the gamma-ray spectrometer currently flying on NASA's Mercury MESSENGER spacecraft. Specifically, infrared shielding techniques allow for a vast reduction of thermal load. This in turn allows for a smaller, lighter-weight design, well-suited for a hand-held instrument. Three working prototypes have been built and tested in the lab. The measured energy resolution is 3 keV fwhm at 662 keV gamma-rays. This paper will focus on the design and performance of the instrument.

  11. Use of the mini-MAC scale in the evaluation of mental adjustment to cancer.

    Science.gov (United States)

    Czerw, Aleksandra Izabela; Marek, Ewelina; Deptała, Andrzej

    2015-01-01

    The objective of the study was to evaluate mental adjustment to cancer in patients diagnosed with an oncologic disease through identification of the coping strategies they had adopted. Seventy-four patients of the Clinic of Oncology and Haematology at the Central Clinical Hospital (CSK) of the Ministry of Interior (MSW) in Warsaw were included in the study. The degree of adaptation to cancer was evaluated with the use of the mini-Mental Adjustment to Cancer (mini-MAC) scale. The individual subscales, i.e. fighting spirit, positive redefinition, helplessness-hopelessness, and anxious preoccupation, were collated with socio-demographic characteristics. Study findings indicate that: 1) tumour patients typically manifest behaviour that allows one to identify their adjustment to cancer; 2) in malignant tumour patients constructive behaviour prevails over destructive behaviour; 3) the helplessness-hopelessness response is more pronounced in men than women; 4) metastatic patients manifest stronger helplessness-hopelessness response than patients with locally limited tumours; 5) pensioners more often than people of working age adopt the helplessness-hopelessness strategy; and 6) patients with the shortest disease period manifest the strongest fighting spirit. Cancer patients employ various strategies of coping with disease depending on socio-demographic factors.

  12. Feasibility of mini-tablets as a flexible drug delivery tool.

    Science.gov (United States)

    Mitra, Biplob; Chang, Jessica; Wu, Sy-Juen; Wolfe, Chad N; Ternik, Robert L; Gunter, Thomas Z; Victor, Michael C

    2017-06-15

    Mini-tablets have potential applications as a flexible drug delivery tool in addition to their generally perceived use as multi-particulates. That is, mini-tablets could provide flexibility in dose finding studies and/or allow for combination therapies in the clinic. Moreover, mini-tablets with well controlled quality attributes could be a prudent choice for administering solid dosage forms as a single unit or composite of multiple mini-tablets in patient populations with swallowing difficulties (e.g., pediatric and geriatric populations). This work demonstrated drug substance particle size and concentration ranges that achieve acceptable mini-tablet quality attributes for use as a single or composite dosage unit. Immediate release and orally disintegrating mini-tablet formulations with 30μm to 350μm (particle size d 90 ) acetaminophen and Compap™ L (90% acetaminophen) at concentrations equivalent to 6.7% and 26.7% acetaminophen were evaluated. Mini-tablets achieved acceptable weight variability, tensile strength, friability, and disintegration time at a reasonable solid fraction for each formulation. The content uniformity was acceptable for mini-tablets of 6.7% formulations with ≤170μm drug substance, mini-tablets of all 26.7% formulations, and composite dosage units containing five or more mini-tablets of any formulation. Results supported the manufacturing feasibility of quality mini-tablets, and their applicability as a flexible drug delivery tool. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Predicting everyday functional abilities of dementia patients with the Mini-Mental State Examination.

    Science.gov (United States)

    Razani, Jill; Wong, Jennifer T; Dafaeeboini, Natalia; Edwards-Lee, Terri; Lu, Po; Alessi, Cathy; Josephson, Karen

    2009-03-01

    The Mini-Mental State Examination is a widely used cognitive screening measure. The purpose of the present study was to assess how 5 specific clusters of Mini-Mental State Examination items (ie, subscores) correlate with and predict specific areas of daily functioning in dementia patients, 61 patients with varied forms of dementia were administered the Mini-Mental State Examination and an observation-based daily functional test (the Direct Assessment of Functional Status). The results revealed that the orientation and attention subscores of the Mini-Mental State Examination correlated most significantly with most functional domains. The Mini-Mental State Examination language items correlated with all but the shopping and time orientation tasks, while the Mini-Mental State Examination recall items correlated with the Direct Assessment of Functional Status time orientation and shopping tasks. Stepwise regression analyses found that among the Mini-Mental State Examination subscores, orientation was the single, best independent predictor of daily functioning.

  14. Trends in diagnosis and control of bovine mastitis: a review.

    Science.gov (United States)

    Deb, Rajib; Kumar, Amit; Chakraborty, Sandip; Verma, Amit Kumar; Tiwari, Ruchi; Dhama, Kuldeep; Singh, Umesh; Kumar, Sushil

    2013-12-01

    Mastitis (inflammation of mammary gland) is a most devastating disease condition in terms of economic losses occurring throughout the world. The etiological agents may vary from place to place depending on climate; animal species and animal husbandry and include wide variety of gram positive and gram negative bacteria; and fungi. They may be either contagious viz. Staphylococcus aureus; Streptococcus agalactiae or environmental viz. S. dysgalactiae, S. uberis, Corynebacterium bovis and Coagulase negative Staphylococcus. Conventional diagnostic tests viz. California Mastitis Test (CMT); R-mastitest and Mast-O-test methods are applied under field conditions; whereas somatic cell count and Bulk Tank Somatic Cell Count (BTSCC) are useful for early mastitis detection and detection of sub clinical or chronic mastitis respectively. In vitro culture based diagnosis require further study as they can detect only viable cells. The advent of Polymerase Chain Reaction (PCR) technology along with its various versions like multiplex and real time PCR has improved the rapidity and sensitivity of diagnosis. Circulating micro RNA (miRNA) based diagnosis; immune assay and proteomics based detection along with biochips and biosensors prove to be asset to diagnosticians for advanced diagnosis of this economically important condition. Improvement of milking hygiene; implementation of post-milking teat disinfection; regular control of the milking equipments; implementation of milking order; Improvement of bedding material are the general measures to prevent new cases of mastitis. The use of antibiotics (intramammary infusions; bacteriocins) and herbs (Terminalia spp.) are important for prophylaxis and therapeutics. Vaccines viz. cell based; Recombinant (staphylococcal enterotoxin type C mutant) or chimeric (pauA); live (S. uberis 0140J stain based) and bacterial surface extract based; DNA-based and DNA-protein based have greatly aided in management of bovine mastitis. Quorum sensing and

  15. Portable mini gamma camera for medical applications

    CERN Document Server

    Porras, E; Benlloch, J M; El-Djalil-Kadi-Hanifi, M; López, S; Pavon, N; Ruiz, J A; Sánchez, F; Sebastiá, A

    2002-01-01

    A small, portable and low-cost gamma camera for medical applications has been developed and clinically tested. This camera, based on a scintillator crystal and a Position Sensitive Photo-Multiplier Tube, has a useful field of view of 4.6 cm diameter and provides 2.2 mm of intrinsic spatial resolution. Its mobility and light weight allow to reach the patient from any desired direction. This camera images small organs with high efficiency and so addresses the demand for devices of specific clinical applications. In this paper, we present the camera and briefly describe the procedures that have led us to choose its configuration and the image reconstruction method. The clinical tests and diagnostic capability are also presented and discussed.

  16. Beta-spectrometer with magnetic filter of mini orange type

    International Nuclear Information System (INIS)

    Gorozhankin, V.M.; Gromov, K.Ya.; Kalinnikov, V.G.; Sereeter, Z.; Fominykh, V.I.; Malikov, Sh.R.; Yuldashev, M.B.

    1997-01-01

    At the ISOL facility YASNAPP-2 a β-spectrometer with a magnetic filter of the miniorange type is constructed to measure γ-ray internal conversion coefficients. The magnetic filter of the mini orange type is an assemblage of permanent magnets creating a toroidal magnetic field perpendicular to the electron trajectories from the source to the Si(Li) detector. The chosen profile of the permanent magnets allowed electron registration in the defined energy energy interval with some transmission increase. There are two sets of permanent magnets of the different thickness. Varying the type and number of permanent magnets one can set the detected electron energy intervals in a 50-2500 keV range. The efficiency of the spectrometer was investigated for different assemblages of the mini orange magnet. The facility can be used for the e-γ coincidence investigation. (A.A.D.)

  17. Mini-Uav LIDAR for Power Line Inspection

    Science.gov (United States)

    Teng, G. E.; Zhou, M.; Li, C. R.; Wu, H. H.; Li, W.; Meng, F. R.; Zhou, C. C.; Ma, L.

    2017-09-01

    Light detection and ranging (LIDAR) system based on unmanned aerial vehicles (UAVs) recently are in rapid advancement, meanwhile portable and flexible mini-UAV-borne laser scanners have been a hot research field, especially for the complex terrain survey in the mountains and other areas. This study proposes a power line inspection system solution based on mini-UAV-borne LIDAR system-AOEagle, developed by Academy of Opto-Electronics, Chinese Academy of Sciences, which mounted on a Multi-rotor unmanned aerial vehicle for complex terrain survey according to real test. Furthermore, the point cloud data was explored to validate its applicability for power line inspection, in terms of corridor and line laser point clouds; deformation detection of power towers, etc. The feasibility and advantages of AOEagle have been demonstrated by the promising results based on the real-measured data in the field of power line inspection.

  18. Toward Solution of the MiniBooNE-LSND Anomalies

    International Nuclear Information System (INIS)

    Karagiorgi, G.

    2012-01-01

    The LSND experiment has observed an anomalous excess of ν ¯ e events in a ν ¯ μ beam which can be interpreted as two-neutrino ν ¯ μ →ν ¯ e oscillations at Δm 2 ∼1 eV 2 , suggesting new physics. The MiniBooNE experiment has ruled out the LSND two-neutrino oscillation interpretation by looking for corresponding flavor oscillations in a neutrino beam, and assuming CP and CPT conservation. However, it has observed an anomalous excess of ν e events at low energy, which, to date, remains unexplained. The two excess signatures are discussed within the context of light sterile neutrino oscillations, and are further confronted with the latest results from a MiniBooNE search for ν ¯ μ →ν ¯ e oscillations in an antineutrino beam. Alternative interpretations are also referenced, along with possible future experimental tests.

  19. Methods for roof-top mini-arrays

    Science.gov (United States)

    Hazen, W. E.; Hazen, E. S.

    1985-08-01

    To test the idea of the Linsley effect mini array for the study of giant air showers, it is desirable to have a trigger that exploits the effect itself. In addition to the trigger, it is necessary to have a method for measuring the relative arrival times of the particle swarm selected by the trigger. Since the idea of mini arrays is likely to appeal to small research groups, it is desirable to try to design relatively simple and inexpensive methods, and methods that utilize existing detectors. Clusters of small detectors have been designed for operation in the local particle density realm where the probability of or = 2 particles per detector is small. Consequently, this method can discriminate pulses from each detector and thenceforth deal mainly with logic pulses.

  20. Validation Study of the Mini-Mental State Examination in Urdu Language for Pakistani Population.

    Science.gov (United States)

    Awan, Safia; Shahbaz, Naila; Akhtar, Syed Wasim; Ahmad, Arsalan; Iqbal, Sadaf; Ahmed, Sellal; Naqvi, Haider; Wasay, Mohammad

    2015-01-01

    Validation study of the Mini-Mental State Examination in Urdu language for Pakistani population. This study was conducted primarily to validate and determine the optimal cutoff score in the diagnosis of dementia among Pakistani's and study the effects of gender and education on the MMSE performance in our population. Four hundred participants took part in the study. Patient with dementia recruited from five major hospitals from Pakistan. The MMSE was translated into Urdu. There were 61 men and 39 women in dementia group and 225 men and 75 women in the control group. The mean score of Urdu MMSE were lower in patients with dementia 18.5 ± 5.6 (range 0-30) as compared to the controls 26.8 ± 2.6 (range 7-30). This difference between groups was statistically significant (p<0.001). Educational based MMSE score below 15 yielded perfect sensitivity and specificity for the diagnosis of dementia. These finding confirm the influence of level of education on MMSE score and education stratified cutoff scores should be used while screening for cognitive impairment in this population.

  1. Mini-Invasive floating metatarsal osteotomy for resistant or recurrent neuropathic plantar metatarsal head ulcers.

    Science.gov (United States)

    Tamir, Eran; Finestone, Aharon S; Avisar, Erez; Agar, Gabriel

    2016-07-11

    Patients with peripheral neuropathy and pressure under a relatively plantar deviated metatarsal head frequently develop plantar foot ulcers. When conservative management with orthotics and shoes does not cure the ulcer, surgical metatarsal osteotomy may be indicated to relieve the pressure and enable the ulcer to heal. The purpose of this study is to evaluate the use of a mini-invasive floating metatarsal osteotomy in treating recalcitrant ulcers or recurrent ulcers plantar to the metatarsal heads in patients with diabetes mellitus (DM) related neuropathy. Computerized medical files of patients with diabetic neuropathy treated with an osteotomy during 2013 and 2014 were retrospectively reviewed. There were 20 osteotomies performed on 17 patients (mean age 58 years). The patients had a diagnosis of DM for a mean of 17 years. All ulcers were University of Texas grade 1A; mean ulcer age was 19 months. After 17/20 operations, the ulcer completely resolved after 6 weeks and did not recur after a mean follow-up of 11.5 months. One patient developed an early post-operative infection with osteomyelitis at the osteotomy site (proximal shaft of the fifth metatarsal) that needed debridement and IV antibiotics. In the other 19 cases, the surgical wound healed within 1 week. Asymptomatic radiological non-union developed in six cases (30 %). Mini-invasive floating metatarsal osteotomy can cure resistant and recurrent University of Texas grade 1A ulcerations plantar to the metatarsal heads in neuropathic patients.

  2. The efficacy of maxillary protraction protocols with the micro-implant-assisted rapid palatal expander (MARPE) and the novel N2 mini-implant-a finite element study.

    Science.gov (United States)

    Moon, Won; Wu, Kimberley W; MacGinnis, Matthew; Sung, Jay; Chu, Howard; Youssef, George; Machado, Andre

    2015-01-01

    Maxillary protraction with the novel N2 mini-implant- and micro-implant-assisted rapid palatal expander (MARPE) can potentially provide significant skeletal effects without surgery, even in older patients where conventional facemask therapy has limited skeletal effects. However, the skeletal effects of altering the location and direction of force from mini-implant-assisted maxillary protraction have not been extensively analyzed. In this study, the application of the novel N2 mini-implant as an orthopedic anchorage device is explored in its ability to treat patients with class III malocclusions. A 3D cranial mesh model with associated sutures was developed from CT images and Mimics modeling software. Utilizing ANSYS simulation software, protraction forces were applied at different locations and directions to simulate conventional facemask therapy and seven maxillary protraction protocols utilizing the novel N2 mini-implant. Stress distribution and displacement were analyzed. Video animations and superimpositions were created. By changing the vector of force and location of N2 mini-implant, the maxilla was displaced differentially. Varying degrees of forward, downward, and rotational movements were observed in each case. For brachyfacial patients, anterior micro-implant-supported protraction at -45° or intermaxillary class III elastics at -45° are recommended. For dolicofacial patients, either anterior micro-implants at -15° or an intermaxillary spring at +30° is recommended. For mesofacial patients with favorable vertical maxillary position, palatal micro-implants at -30° are recommended; anterior micro-implants at -30° are preferred for shallow bites. For patients with a severe mid-facial deficiency, intermaxillary class III elastics at -30° are most effective in promoting anterior growth of the maxilla. By varying the location of N2 mini-implants and vector of class III mechanics, clinicians can differentially alter the magnitude of forward, downward, and

  3. Diagnosis of adrenal tumors

    Energy Technology Data Exchange (ETDEWEB)

    Richter, E.I.; Loesch, H.

    1987-09-01

    Of 155 patients with adrenal disorders, 120 (77%) were correctly diagnosed as negative. There were no correlations between the results of computer tomography and phlebography or between computer tomography and laboratory tests. In 31 patients (20%) a correct diagnosis was obtained and these patients were sent to surgery. Four cases (3%) were shown to be false positive. In these cases (with one exception), both the computer tomography and phlebography results had been overinterpreted. Computer tomography was shown to be a method of high sensitivity and almost as great specificity. Tumors cannot be distinguished by phlebography; only pheochromocytoma shows a characteristic alteration of vessels in arteriograms. In general, an accurate diagnosis requires positive angiography (arterio- or phlebography) results and clear evidence of elevated hormone levels. Only then is surgery indicated.

  4. Diagnosis of adrenal tumors

    International Nuclear Information System (INIS)

    Richter, E.I.; Loesch, H.

    1987-01-01

    Of 155 patients with adrenal disorders, 120 (77%) were correctly diagnosed as negative. There were no correlations between the results of computer tomography and phlebography or between computer tomography and laboratory tests. In 31 patients (20%) a correct diagnosis was obtained and these patients were sent to surgery. Four cases (3%) were shown to be false positive. In these cases (with one exception), both the computer tomography and phlebography results had been overinterpreted. Computer tomography was shown to be a method of high sensitivity and almost as great specificity. Tumors cannot be distinguished by phlebography; only pheochromocytoma shows a characteristic alteration of vessels in arteriograms. In general, an accurate diagnosis requires positive angiography (arterio- or phlebography) results and clear evidence of elevated hormone levels. Only then is surgery indicated. (orig.) [de

  5. Automated material interface (AMI) for mini-environment technology

    International Nuclear Information System (INIS)

    Wolf, M.; Fleming, J.; Mueller, R.; Pulaski, L.

    1993-01-01

    The Automated Material Inter-face or AMI presented here is a new method of automating the input/output of materials or products into mini-environments. The AMI concept and hardware, and preliminary data are presented to show that neither the automation hardware nor the product isolation carrier contribute any significant contamination to the product during the I/O process. Budgetary estimates are presented which support the AMI concept for cost effective manufacturing of advanced semiconductors and disk media

  6. Reliability and validity of revised Turkish version of Mini Mental State Examination (rMMSE-T) in community-dwelling educated and uneducated elderly.

    Science.gov (United States)

    Keskinoglu, Pembe; Ucku, Reyhan; Yener, Görsev; Yaka, Erdem; Kurt, Pinar; Tunca, Zeliha

    2009-11-01

    To evaluate the reliability and validity of the revised Turkish version of Mini Mental State Examination (rMMSE-T) in educated and uneducated community-dwelling elderly, to re-organize the present Turkish version of MMSE and to determine cut-off point of the revised test. This cross-sectional and analytical study involved totally 490 elderly subjects selected by cluster sampling method. Receiver operating characteristic (ROC) analysis, kappa analysis and Cronbach's alpha coefficients were used for statistical analysis. Areas under ROC curve in educated and uneducated elderly were found as 0.953 and 0.907. Cut-off point of 22/23 of rMMSE-T in educated elderly had the highest sensitivity (90.9), specificity (97.0) and positive likelihood ratio (30.3), whereas cut-off point of 18/19 of the test in uneducated elderly had the highest sensitivity (82.7), specificity (92.3) and positive likelihood ratio (10.7). The Cronbach's alpha values of the rMMSE-T for educated and uneducated elderly were higher than 0.7 (sign of good internal consistency of the test). A significant correlations between intrarater and interrater test-retest in educated elderly subjects were observed (0.966 (p = 0.000); 0.855 (p = 0.000), respectively), and also in uneducated elderly (0.988 (p = 0.000); 0.934 (p = 0.000), respectively). Kappa value of the test in educated and uneducated elderly showed a perfect agreement interraters (1.000) and a substantial agreement in intraraters (1.000, 0.784; 0.826, 0.656, respectively). rMMSE-T had a high reliability and validity. It will be more appropriate to use the revised test and the new cut-off point for the diagnosis and screening of dementia among community-dwelling Turkish elderly population. Copyright 2009 John Wiley & Sons, Ltd.

  7. Quantification of intrusive/retraction force and moment generated during en-masse retraction of maxillary anterior teeth using mini-implants: A conceptual approach

    Directory of Open Access Journals (Sweden)

    A. Sumathi Felicita

    Full Text Available ABSTRACT Objective: The aim of the present study was to clarify the biomechanics of en-masse retraction of the upper anterior teeth and attempt to quantify the different forces and moments generated using mini-implants and to calculate the amount of applied force optimal for en-masse intrusion and retraction using mini-implants. Methods: The optimum force required for en-masse intrusion and retraction can be calculated by using simple mathematical formulae. Depending on the position of the mini-implant and the relationship of the attachment to the center of resistance of the anterior segment, different clinical outcomes are encountered. Using certain mathematical formulae, accurate measurements of the magnitude of force and moment generated on the teeth can be calculated for each clinical outcome. Results: Optimum force for en-masse intrusion and retraction of maxillary anterior teeth is 212 grams per side. Force applied at an angle of 5o to 16o from the occlusal plane produce intrusive and retraction force components that are within the physiologic limit. Conclusion: Different clinical outcomes are encountered depending on the position of the mini-implant and the length of the attachment. It is possible to calculate the forces and moments generated for any given magnitude of applied force. The orthodontist can apply the basic biomechanical principles mentioned in this study to calculate the forces and moments for different hypothetical clinical scenarios.

  8. Mini-implants in the palatal slope – a retrospective analysis of implant survival and tissue reaction

    Directory of Open Access Journals (Sweden)

    Ziebura Thomas

    2012-11-01

    Full Text Available Abstract Background To identify insertion procedure and force application related complications in Jet Screw (JS type mini-implants when inserted in the palatal slope. Methods Setting and Sample Population: The Department of Orthodontics, the University Hospital Münster. Forty-one consecutively started patients treated using mini-implants in the palatal slope. In this retrospective study, 66 JS were evaluated. Patient records were used to obtain data on the mode of utilization and complications. Standardized photographs overlayed with a virtual grid served to test the hypothesis that deviations from the recommended insertion site or the type of mechanics applied might be related to complications regarding bleeding, gingival overgrowth or implant failure. Results Two implants (3% were lost, and two implants (3%, both loaded with a laterally directed force, exhibited loosening while still serving for anchorage. Complications that required treatment did not occur, the most severe problem observed being gingival proliferation which was attributable neither to patients’ age nor to applied mechanics or deviations from the ideal implant position. Conclusions The JS mini-implant is reliable for sagittal and vertical movements or anchorage purposes. Laterally directed forces might be unfavorable. The selection of implant length as well as the insertion procedure should account for the possibility of gingival overgrowth.

  9. Vaporization inside a mini microfin tube: experimental results and modeling

    Science.gov (United States)

    Diani, A.; Rossetto, L.

    2015-11-01

    This paper proposes a comparison among the common R134a and the extremely low GWP refrigerant R1234yf during vaporization inside a mini microfin tube. This microfin tube has an internal diameter of 2.4 mm, it has 40 fins, with a fin height of 0.12 mm. Due to the high heat transfer coefficients shown by this tube, this technology can lead to a refrigerant charge reduction. Tests were run in the Heat Transfer in Micro Geometries Lab of the Dipartimento di Ingegneria Industriale of the Università di Padova. Mass velocities range between 375 and 940 kg m-2 s-1, heat fluxes from 10 to 50 kW m-2, vapour qualities from 0.10 to 0.99, at a saturation temperature of 30°C. The comparison among the two fluids is proposed at the same operating conditions, in order to highlight the heat transfer and pressure drop differences among the two refrigerants. In addition, two correlations are proposed to estimate the heat transfer coefficient and frictional pressure drop during refrigerant flow boiling inside mini microfin tubes. These correlations well predict the experimental values, and thus they can be used as a useful tool to design evaporators based on these mini microfin tubes.

  10. Design of the MiniSLAR system for Bruce A

    International Nuclear Information System (INIS)

    Gray, M.G.

    1995-01-01

    Cancellation of Bruce A Retube created the need to perform SLAR on Unit 1. The existing SLAR system cannot reach Unit 1 and alternative systems had limitations. The concept and design of MiniSLAR were driven by the availability of existing components made for Retube. The MiniSLAR concept was developed by a team with members representing operators, technicians, and designers from various departments within Ontario Hydro and GE Canada. Overall project leadership was provided by Bruce A Projects and Modifications Department with assistance from Ontario Hydro Nuclear Technology Services. The responsibility for detailed design was assigned by Ontario Hydro to GE Canada. The detailed design proceeded with continual input and review by the team. The MiniSLAR delivery machine consists of a closure removal ram, a shield plug removal ram and a SLAR tool delivery ram attached to the sliding plate of a horizontal indexing mechanism. The moving plate is constrained by guide rails to a fixed plate and seals against it with o-rings. A snout and clamping mechanism mounts on the front of the fixed plate. The machine mounts atop a work table which provides the various motions required for endfitting engagement. Some operations are performed manually while others are remote and automatic. (author)

  11. The Mini-EUSO telescope on the ISS

    Energy Technology Data Exchange (ETDEWEB)

    Scotti, Valentina, E-mail: scottiv@na.infn.it; Osteria, Giuseppe

    2017-02-11

    The Mini-EUSO project aims to perform observations of the UV-light night emission from Earth. The UV background produced in atmosphere is a key measurement for any experiment aiming at the observation of Extreme Energy Cosmic Rays (EECR) from space, the most energetic component of the cosmic radiation. The Mini-EUSO instrument will be placed within the International Space Station (ISS) in the Russian Module and measures through a UV transparent window. The instrument comprises a compact telescope with a large field of view, based on an optical system employing two Fresnel lenses for increased light collection. The light is focused onto an array of photo-multipliers and the resulting signal is converted into digital, processed and stored via the electronics subsystems on-board. The instrument is designed and built by the members of the JEM-EUSO collaboration. JEM-EUSO is a wide-angle refractive UV telescope being proposed for attachment to the ISS, which has been designed to address basic problems of fundamental physics and high-energy astrophysics investigating the nature of cosmic rays with energies above 10{sup 20} eV. Mini-EUSO will be able to study beside EECRs a wide range of scientific phenomena including atmospheric physics, strange quark matter and bioluminescence. The mission is approved by the Italian Space Agency and the Russian Space Agency. Scientific, technical and programmatic aspects of this project will be described.

  12. A mini axial and a permanent maglev radial heart pump.

    Science.gov (United States)

    Qian, Kun-Xi; Ru, Wei-Min; Wang, Hao; Jing, Teng

    2007-05-31

    The implantability and durability have been for decades the focus of artificial heart R&D. A mini axial and a maglev radial pump have been developed to meet with such requirements.The mini axial pump weighing 27g (incl.5g rotor) has an outer diameter of 21mm and a length of 10mm in its largest point, but can produce a maximal blood flow of 6l/min with 50mmHg pressure increase. Therefore, it is suitable for the patients of 40-60kg body weight. For other patients of 60-80kg or 80-100kg body weight, the mini axial pumps of 23mm and 25mm outer diameter had been developed before, these devices were acknowledged to be the world smallest LVADs by Guinness World Record Center in 2004.The permanent maglev radial pump weighing 150g is a shaft-less centrifugal pump with permanent magnetic bearings developed by the author. It needs no second coil for suspension of the rotor except the motor coil, different from all other maglev pumps developed in USA, Japan, European, etc. Thus no detecting and controlling systems as well as no additional power supply for maglev are necessary. The pump can produce a blood flow up to as large as 10l/min against 100mmHg pressure.An implantable and durable blood pump will be a viable alternative to natural donor heart for transplantation.

  13. Support for designing waste sorting systems: A mini review.

    Science.gov (United States)

    Rousta, Kamran; Ordoñez, Isabel; Bolton, Kim; Dahlén, Lisa

    2017-11-01

    This article presents a mini review of research aimed at understanding material recovery from municipal solid waste. It focuses on two areas, waste sorting behaviour and collection systems, so that research on the link between these areas could be identified and evaluated. The main results presented and the methods used in the articles are categorised and appraised. The mini review reveals that most of the work that offered design guidelines for waste management systems was based on optimising technical aspects only. In contrast, most of the work that focused on user involvement did not consider developing the technical aspects of the system, but was limited to studies of user behaviour. The only clear consensus among the articles that link user involvement with the technical system is that convenient waste collection infrastructure is crucial for supporting source separation. This mini review reveals that even though the connection between sorting behaviour and technical infrastructure has been explored and described in some articles, there is still a gap when using this knowledge to design waste sorting systems. Future research in this field would benefit from being multidisciplinary and from using complementary methods, so that holistic solutions for material recirculation can be identified. It would be beneficial to actively involve users when developing sorting infrastructures, to be sure to provide a waste management system that will be properly used by them.

  14. Establishment and Efficiency Evaluation of a Simple Mini hatchery for production of Oreochromis niloticus (GIFT strain seeds

    Directory of Open Access Journals (Sweden)

    M.P.K.S.K. De Silva

    2015-06-01

    Full Text Available A simple technology mini hatchery was established for small scale farmers to meet their own GIFT seed requirements. Different shapes and sizes of jars were trialed for incubation of eggs and yolk-sac larvae. Concaved bottom round plastic bottles (4 L and rectangular (3 L plastic trays gave the best hatchability of eggs and survival of yolk-sac larvae respectively. The best stocking density was 500 eggs/larvae L-1. Optimised flow rate into the incubation bottles and rearing trays were 2.70±0.18 L min-1 and 5.40±0.14 L min-1 respectively. Two gravel filters (15 L and 20 L made with discarded and low cost material purified the water from the incubation containers and directed into a water recirculation system. Production efficiency of this mini hatchery was compared with a hapa breeding method. Two hapas having 10 m3 size and 1.6 mm mesh were positioned in an earthen pond. Each hapa was stocked with 40 GIFT broodfish at 1:1 female to male ratio. In Phase I of the study (60 days, eggs collected from Hapa I were placed in incubation bottles and hatchability and survival rate were determined. In parallel, free-swimming fry were collected and counted from the Hapa II at every 14 days. The study continued in the same way for Phase II (next 60 days by interchanging the brood fish between Hapa I and Hapa II. Yield from the mini hatchery (24,000 fry was significantly different (P≤0.05 from hapa method (4,879 fry indicating that this established mini hatchery could serve as a productive model to support small scale farmers in GIFT seed production.

  15. A mini-encyclopedia of nuclear energy

    International Nuclear Information System (INIS)

    Istenic, Radko; Stritar, Andrej

    2002-01-01

    Atlas of Nuclear Technology is a central publication for the public information activities of the Nuclear Society of Slovenia. We started inviting schoolchildren, students and general public to lectures about radioactivity and nuclear technology already in 1993. Since that time we published many information-nation materials in Slovenian language for our visitors and updated the technical content of the Information-nation Centre several times. After a few years we realized how important it would be that every visitor would leave the Information Centre with some lasting interesting and easily understandable information in a single booklet. Therefore we updated and compiled all the available information panels from the Information Centre, separate leaflets and view-graphs from the lectures and added some essential text that is easily understood also by non-technical persons. From the very beginning we decided that there would be a lot of illustrations and that the text would be in Slovenian and English language in parallel. What finally emerged was a booklet of 60 pages, which we call 'Atlas of Nuclear Technology'. Contents include chapters on physics, TRIGA research reactor, Slovenian energy production, greenhouse effect, nuclear energy in the world, Krsko nuclear power plant, radioactive waste and nuclear accidents. Some 10 000 booklets were printed and are being distributed to the visitors. We refer to the Atlas during the lectures that are typically attended by 50 - 60 8-graders (up to 8000 per year) accompanied by several teachers. The response is very favorable. We get a lot of positive feedback and samples of posters that the schoolchildren have prepared as their homework using the Atlas as the main source of information. Also our yearly poll shows a steady good acceptance of nuclear energy among the youngsters. (author)

  16. Heat transfer and pressure drop characteristics of mini-fin structures

    International Nuclear Information System (INIS)

    Jiang Peixue; Xu Ruina

    2007-01-01

    Forced convection heat transfer of air and water in bronze and pure copper mini-fin structures and mini-channel structures was investigated experimentally. The mini-fin dimensions were 0.7 mm x 0.2 mm and 0.8 mm x 0.4 mm. The tests included both staggered diamond-shaped and in-line square mini-fin arrangements. The tests investigated the effects of structures, mini-fin dimensions and arrangement, test section materials, and fluid properties on the convection heat transfer and heat transfer enhancement. For the tested conditions, the convection heat transfer coefficient was increased 9-21 fold for water and 12-38 fold for air in the mini-fin structures compared with an empty plate channel. The friction factor and flow resistance in the mini-channel structures and the in-line square mini-fin arrangement were much less than in the staggered diamond-shaped mini-fin arrangement. For the small channel width, W c = 0.2 mm, the convection heat transfer with the in-line square array structure was more intense than with the staggered diamond-shaped structure, the mini-channel structure or the porous media. For the larger channel width, W c = 0.4 mm, the convection heat transfer in the staggered diamond-shaped array structure was more intense than in the others systems while the in-line square structure had the best overall thermal-hydraulic performance

  17. Aspects of alcohol use disorder affecting social cognition as assessed using the Mini Social and Emotional Assessment (mini-SEA).

    Science.gov (United States)

    Cox, Sharon; Bertoux, Maxime; Turner, John J D; Moss, Antony; Locker, Kirsty; Riggs, Kevin

    2018-04-10

    Alcohol Use Disorder (AUD) is associated with problems with processing complex social scenarios. Little is known about the relationship between distinct AUD-related factors (e.g., years of problematic drinking), aspects of cognitive function and dysfunction in individuals diagnosed with AUD, and the relative impact these may have on social cognition. To explore differences in social cognition between a group of participants diagnosed with AUD and controls, using a clinical measure, the Mini Social and Emotional Assessment (mini-SEA). The mini-SEA was used to evaluate social and emotional understanding through a facial emotional recognition task and by utilising a series of social scenes some of which contain a faux pas (social error). Eighty-five participants (individuals with AUD and controls) completed demographic questions and a general cognitive and social cognitive test battery over three consecutive days. Between group analyses revealed that the participants with AUD performed less well on the faux pas test, and differences were also revealed in the emotional facial recognition task. Years of problematic alcohol consumption was the strongest predictor of poor ToM reasoning. These results suggest a strong link between AUD chronicity and social cognition, though the direction of this relationship needs further elucidation. This may be of clinical relevance to abstinence and relapse management, as basic social cognition skills and ability to maintain interpersonal relationships are likely to be crucial to recovery. Copyright © 2018 Elsevier B.V. All rights reserved.

  18. Styles of coping with cancer: the Italian version of the Mini-Mental Adjustment to Cancer (Mini-MAC) scale.

    Science.gov (United States)

    Grassi, Luigi; Buda, Patrizia; Cavana, Laura; Annunziata, Maria Antonietta; Torta, Riccardo; Varetto, Antonella

    2005-02-01

    Mental adjustment to cancer has been explored in a large body of the literature by using the Mental Adjustment to Cancer (MAC) scale. Problems in the factor structure of the scale and the need for refining the instrument have determined the development of the Mini-MAC. The aim of this study was to validate, according to a test-oriented approach, the Italian version of the Mini-MAC. Four hundred and thirty cancer patients in five centres in Northern Italy completed the Mini-MAC and the Brief Symptom Inventory (BSI). A subgroup of 153 patients filled out the instruments again within 3 months of the first assessment. The five original subscales (Fighting Spirit, Hopeless, Fatalism, Anxious Preoccupation and Cognitive Avoidance) showed acceptable levels of reliability (Cronbach alpha coefficients ranging from 0.55 to 0.80) although alphas were lower for the scales Fighting Spirit and Fatalism. Factor analysis (Varimax rotation) identified the same five factors with minor variations from the original version. Again, alpha coefficients were less robust for the factors Fighting Sprit and Fatalism. Hopeless and Anxious Preoccupation were significantly related to all the BSI psychological stress symptoms, including the Global Stress Index (GSI). Test-retest reliability showed no differences in the sub-scales scores between assessments. Copyright (c) 2004 John Wiley & Sons, Ltd.

  19. Corneal decompensation following filtering surgery with the Ex-PRESS® mini glaucoma shunt device

    Directory of Open Access Journals (Sweden)

    Tojo N

    2015-03-01

    Full Text Available Naoki Tojo, Atsushi Hayashi, Akio Miyakoshi Department of Ophthalmology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan Purpose: To report a case of corneal decompensation due to the Ex-PRESS® mini glaucoma shunt device (Ex-PRESS.Patient and methods: A 75-year-old man had pseudoexfoliation glaucoma in his right eye. He underwent filtration surgery with Ex-PRESS. His intraocular pressure was 7 mmHg after 9 months.Results: We observed partial decompensation of the corneal endothelium adjacent to the filtering bleb. Specular microscopy revealed a marked decrease in the endothelial cell density at the center of the cornea.Conclusion: Anterior segment optical coherence tomography is very useful for evaluating corneal edema and the position of Ex-PRESS. It is important to follow up with an examination of the corneal endothelial cells. Keywords: Ex-PRESS, bullous keratopathy, trabeculectomy, complication, cornea 

  20. Marginal ulcers after one anastomosis (mini) gastric bypass: a survey of surgeons.

    Science.gov (United States)

    Mahawar, K K; Reed, A N; Graham, Y N H

    2017-06-01

    Many surgeons believe that one anastomosis (mini) gastric bypass (OAGB/MGB) is associated with a high marginal ulcer (MU) rate and that this is associated with complications in a significant number of patients. The purpose of this survey was to find out the participant-reported incidence of MU after OAGB/MGB and its complications. We also aimed to understand practices in this cohort concerning prophylaxis, diagnosis, treatment and management of complications. Bariatric surgeons who perform OAGB/MGB procedures were invited to participate in a confidential, online survey using SurveyMonkey®. A total of 86 surgeons performing OAGB/MGB procedures participated in the survey. The total number of OAGB/MGB procedures reported was 27 672, revealing 622 MU, giving an MU rate of 2.24 %. Most participants (69/84, 82.4%) routinely use proton pump inhibitor (PPI) prophylaxis, but there was variation in drugs, dosages and duration. The majority (49/85, 57.6%) of participants 'always' use endoscopy for diagnosis, and 48.1% (39/81) 'always' perform an endoscopy to ensure healing. Most (49/55) perforated ulcers were treated with laparoscopic repair +/- omentoplasty +/- drainage. Most (55/59, 93.0%) of the bleeding ulcers were managed with PPI +/- blood transfusions +/- endoscopic intervention (23/59, 39.0%). Non-healing ulcers were treated by conversion to Roux-en-Y gastric bypass (RYGB) in 46.5% of patients (n = 20/43). The participants did not report any MU-related mortality but described a number of risk factors for it. This survey is the first detailed attempt to understand the incidence of MU following OAGB/MGB; its complications; and practices concerning prophylaxis, diagnosis, treatment and management of complications. © 2017 World Obesity Federation.

  1. Impact of Mini-drone based Video Surveillance on Invasion of Privacy

    OpenAIRE

    Korshunov, Pavel; Bonetto, Margherita; Ebrahimi, Touradj; Ramponi, Giovanni

    2015-01-01

    An increase in adoption of video surveillance, affecting many aspects of daily lives, raises public concern about an intrusion into individual privacy. New sensing and surveillance technologies, such as mini-drones, threaten to eradicate boundaries of private space even more. Therefore, it is important to study the effect of mini-drones on privacy intrusion and to understand how existing protection privacy filters perform on a video captured by a mini-drone. To this end, we have built a publi...

  2. Replacing a failed mini-implant with a miniplate to prevent interruption during orthodontic treatment.

    Science.gov (United States)

    Lee, Jin-Hwa; Choo, Hyeran; Kim, Seong-Hun; Chung, Kyu-Rhim; Giannuzzi, Lucille A; Ngan, Peter

    2011-06-01

    When mini-implants fail during orthodontic treatment, there is a need to have a backup plan to either replace the failed implant in the adjacent interradicular area or wait for the bone to heal before replacing the mini-implant. We propose a novel way to overcome this problem by replacement with a miniplate so as not to interrupt treatment or prolong treatment time. The indications, advantages, efficacy, and procedures for switching from a mini-implant to a miniplate are discussed. Two patients who required replacement of failed mini-implants are presented. In the first patient, because of the proximity of the buccal vestibule to the mini-implant, it was decided to replace the failed mini-implant by an I-shaped C-tube miniplate. In the second patient, radiolucencies were found around the failed mini-implants, making the adjacent alveolar bone unavailable for immediate placement of another mini-implant. In addition, the maxillary sinus pneumatization was expanded deeply into the interradicular spaces; this further mandated an alternative placement site. One failed mini-implant was examined under a scanning electron microscope for bone attachment. Treatment was completed in both patients after replacement with miniplates without interrupting the treatment mechanics or prolonging the treatments. Examination under the scanning electron microscope showed partial bone growth into the coating pores and titanium substrate interface even after thorough cleaning and sterilization. Replacement with a miniplate is a viable solution for failed mini-implants during orthodontic treatment. The results from microscopic evaluation of the failed mini-implant suggest that stringent guidelines are needed for recycling used mini-implants. Copyright © 2011 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  3. FINANCIAL DIAGNOSIS OF STOCKS

    Directory of Open Access Journals (Sweden)

    SUCIU GHEORGHE

    2014-12-01

    Full Text Available Financial diagnosis is a part of a company’s general diagnosis. The role of the financial diagnosis is to establish the situation of the company at a given time, to see if it is viable, to help the decision-makers to take the best measures to continue or cease the activity, or to sell, buy or liquidate the company. Each entity is unique and arbitrarily applying some analysis models used by other companies can lead to significant errors. One cannot analyze in the same way a company that produces household products and a trade company. In the first one, the working capital must be positive, because permanent capitals must finance the fixed assets which have a high value, and the working capital will finance the operating cycle. In case of a trade company, a negative working capital might represent a positive activity, because the duration of the operating cycle is much shorter, and short term sources can also finance the company’s tangible assets.

  4. [CONSISTENCY OF MINI NUTRITIONAL ASSESSMENT TO IDENTIFY SARCOPENIA IN OLDER ADULTS IN NURSING HOMES IN BOGOTA, COLOMBIA].

    Science.gov (United States)

    Díaz Muñoz, Gustavo Alfonso; Cárdenas Zuluaga, Diana María; Mesa Jimenez, Alfonso

    2015-07-01

    malnutrition and sarcopenia, which have similar physiological mechanisms and are both responsible for adverse health outcomes, are highly prevalent in the elderly. to measure the consistency of the MNA with the diagnosis of sarcopenia in older adults. cross-sectional study of consistency in four nursing homes in Bogotá. The nutritional screening and nutritional assessment were made with the Mini Nutritional Assessment in its long form; the diagnosis of sarcopenia was done with the algorithm and the breakpoints of the European Consensus (EWGSOP). Pearson Chi2, Mann-Whitney and consistency by Cohen's kappa coefficient. we included 108 patients, 62% women, mean age 80.4 years (SD 7.7). The prevalence of sarcopenia, malnutrition and risk of malnutrition were 38.9%, 33.3% and 2.8% respectively. The concordance of the MNA with the diagnosis of sarcopenia was slight (kappa 0.1908 95% CI 0.0025 to 0.3791, p sarcopenia, suggesting that it is not an appropriate tool for the diagnosis of sarcopenia in older institutionalized adults. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  5. A mini-library of TBA analogues containing 3'-3' and 5'-5' inversion of polarity sites.

    Science.gov (United States)

    Esposito, V; Galeone, A; Mayol, L; Randazzo, A; Virgilio, A; Virno, A

    2007-01-01

    Several researches have been devoted to structure-activity relationship and to post-SELEX modifications of the thrombin binding aptamer (TBA), one of the first aptamers discovered by the SELEX methodology. However, no studies on TBA dealing with the effects of introduction of inversion of polarity sites have been reported yet. In this frame, we have undertaken the synthesis and the study of a mini-library composed of several TBA analogues containing a 3'-3' or a 5'-5' inversion of polarity site at different positions into the sequence. Particularly, in this article, we present preliminary results about their structural and biological properties.

  6. The Mini-Cog, Clock Drawing Test, and the Mini-Mental State Examination in a German memory clinic: specificity of separation dementia from depression.

    Science.gov (United States)

    Milian, Monika; Leiherr, Anna-Maria; Straten, Guido; Müller, Stephan; Leyhe, Thomas; Eschweiler, Gerhard W

    2013-01-01

    The aim of this study was to assess the specificities of the Mini-Cog, the Clock Drawing Test (CDT), and the Mini-Mental State Examination (MMSE) against depression and healthy controls in a German Memory Clinic. Furthermore, we analyzed the specificities of all three screening instruments in dependence of actual depression severity. Data from 142 depressed elderly, 438 dementia patients, and 64 healthy controls were retrospectively analyzed. The CDT and an extraction of the three-item recall of the MMSE were used to constitute the Mini-Cog algorithm. Depression severity was rated by either the Beck Depression Inventory (BDI) or the Geriatric Depression Scale (GDS) depending on the age of the patients. The Mini-Cog achieved a specificity of 79.6% against depressed elderly and 100.0% against healthy subjects (p Mini-Cog and the CDT, but also showed the lowest sensitivity for the detection of dementia. Surprisingly, the depression severity had no effect on the specificity of the Mini-Cog and the CDT, only the MMSE was susceptible for the depression severity. Although the MMSE showed higher specificities, the weighting between the sensitivities and specificities in all tests prove again the Mini-Cog as a short, valid, and sensitive screening tool.

  7. Mini-clinical evaluation exercise til evaluering af kommunikation og samarbejde i ambulatoriet

    DEFF Research Database (Denmark)

    Eriksen, Jesper Grau; Simonsen, Dorit; Bastholt, Lars

    2009-01-01

    INTRODUCTION: In the revised Danish medical specialist training increased focus has been placed on competences which are hard to evaluate such as communication skills. Mini-CEX seems promising as an evaluation tool. Our aim was to test: 1) whether mini-CEX was useable in the evaluation of communi......INTRODUCTION: In the revised Danish medical specialist training increased focus has been placed on competences which are hard to evaluate such as communication skills. Mini-CEX seems promising as an evaluation tool. Our aim was to test: 1) whether mini-CEX was useable in the evaluation...

  8. Influence of different implant materials on the primary stability of orthodontic mini-implants.

    Science.gov (United States)

    Pan, Chin-Yun; Chou, Szu-Ting; Tseng, Yu-Chuan; Yang, Yi-Hsin; Wu, Chao-Yi; Lan, Ting-Hsun; Liu, Pao-Hsin; Chang, Hong-Po

    2012-12-01

    This study evaluates the influence of different implant materials on the primary stability of orthodontic mini-implants by measuring the resonance frequency. Twenty-five orthodontic mini-implants with a diameter of 2 mm were used. The first group contained stainless steel mini-implants with two different lengths (10 and 12 mm). The second group included titanium alloy mini-implants with two different lengths (10 and 12 mm) and stainless steel mini-implants 10 mm in length. The mini-implants were inserted into artificial bones with a 2-mm-thick cortical layer and 40 or 20 lb/ft(3) trabecular bone density at insertion depths of 2, 4, and 6 mm. The resonance frequency of the mini-implants in the artificial bone was detected with the Implomates(®) device. Data were analyzed by two-way analysis of variance followed by the Tukey honestly significant difference test (α = 0.05). Greater insertion depth resulted in higher resonance frequency, whereas longer mini-implants showed lower resonance frequency values. However, resonance frequency was not influenced by the implant materials titanium alloy or stainless steel. Therefore, the primary stability of a mini-implant is influenced by insertion depth and not by implant material. Insertion depth is extremely important for primary implant stability and is critical for treatment success. Copyright © 2012. Published by Elsevier B.V.

  9. Influence of different implant materials on the primary stability of orthodontic mini-implants

    Directory of Open Access Journals (Sweden)

    Chin-Yun Pan

    2012-12-01

    Full Text Available This study evaluates the influence of different implant materials on the primary stability of orthodontic mini-implants by measuring the resonance frequency. Twenty-five orthodontic mini-implants with a diameter of 2 mm were used. The first group contained stainless steel mini-implants with two different lengths (10 and 12 mm. The second group included titanium alloy mini-implants with two different lengths (10 and 12 mm and stainless steel mini-implants 10 mm in length. The mini-implants were inserted into artificial bones with a 2-mm-thick cortical layer and 40 or 20 lb/ft3 trabecular bone density at insertion depths of 2, 4, and 6 mm. The resonance frequency of the mini-implants in the artificial bone was detected with the Implomates® device. Data were analyzed by two-way analysis of variance followed by the Tukey honestly significant difference test (α = 0.05. Greater insertion depth resulted in higher resonance frequency, whereas longer mini-implants showed lower resonance frequency values. However, resonance frequency was not influenced by the implant materials titanium alloy or stainless steel. Therefore, the primary stability of a mini-implant is influenced by insertion depth and not by implant material. Insertion depth is extremely important for primary implant stability and is critical for treatment success.

  10. Validação da versão em português do Mini-Inventário de Fobia Social (Mini-SPIN) Validation of the portuguese version of the Mini-Social Phobia Inventory (Mini-SPIN)

    OpenAIRE

    Gustavo José Fonseca D'El Rey; Cláudia Wilmor Matos

    2009-01-01

    A fobia social (também conhecida como transtorno de ansiedade social) é um grave transtorno mental que traz sofrimento e incapacitação. O objetivo deste estudo foi validar para a língua portuguesa o Mini-Inventário de Fobia Social (Mini-SPIN) em uma amostra da população. Foi realizado um estudo da validade discriminativa do Mini-SPIN em uma amostra de 644 pessoas (grupo positivo para o Mini-SPIN: n = 218 e grupo controle/negativo: n = 426) de um estudo de prevalência de transtornos de ansieda...

  11. Effect of Recycling Protocol on Mechanical Strength of Used Mini-Implants

    OpenAIRE

    Estelita, Sérgio; Janson, Guilherme; Chiqueto, Kelly; Ferreira, Eduardo Silveira

    2014-01-01

    Purpose. This study evaluated the influence of recycling process on the torsional strength of mini-implants. Materials and Methods. Two hundred mini-implants were divided into 4 groups with 50 screws equally distributed in five diameters (1.3 to 1.7 mm): control group (CG): unused mini-implants, G1: mini-implants inserted in pig iliac bone and removed, G2: same protocol of group 1 followed by sonication for cleaning and autoclave sterilization, and G3: same insertion protocol of group 1 follo...

  12. Energy efficient mini bars in hotel rooms; Energieffektive minibarer til hotelvaerelser

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-12-15

    The project 'Energy-efficient mini bars for hotel rooms' is carried out from February December 2005. The project is financed by Elfor's PSO funds and also by the participants in the project, HORESTA and Teknologisk Institut. Mini bars consume up to 10% of the total electricity costs of a hotel. Therefore, the energy consumption of mini bars has been brought into focus in this project. The existing mini bar market has been analysed and measurements have been carried out on the type of mini bars that are used most often. In that way, energy consumption, net volume, energy efficiency, energy labelling, noise level and cooling capacity have been determined. In the course of the project, mini bars from IndelB, Domestic and Vibocold have been tested. With regard to energy consumption, the test results showed large deviations from the consumption stated by the manufacturer. Only 1 of the 6 tested mini bars received an energy label B - the others were labelled with F or G. Therefore, there is a great potential for developing more energy efficient mini bars. A list covering the energy consumption, energy labelling, noise level etc. of the tested mini bars and a guide to new purchases can be found on HORESTA's homepage www.horesta.dk. (au)

  13. Report on a 2009 mini-demonstration of the ARG-US Radio Frequency Identification (RFID) system in transportation

    International Nuclear Information System (INIS)

    Tsai, H.; Chen, K.; Jusko, M.; Craig, B.; Liu, Y.

    2009-01-01

    The Packaging Certification Program (PCP) of the U.S. Department of Energy (DOE) Environmental Management (EM), Office of Packaging and Transportation (EM-14), has developed a radio frequency identification (RFID) tracking and monitoring system for the management of nuclear materials during storage and transportation. The system, developed by the PCP team at Argonne National Laboratory, consists of hardware (Mk-series sensor tags, fixed and handheld readers, form factor for multiple drum types, seal integrity sensors, and enhanced battery management), software (application programming interface, ARG-US software for local and remote/web applications, secure server and database management), and cellular/satellite communication interfaces for vehicle tracking and item monitoring during transport. The ability of the above system to provide accurate, real-time tracking and monitoring of the status of multiple, certified containers of nuclear materials has been successfully demonstrated in a week-long, 1,700-mile DEMO performed in April 2008. While the feedback from the approximately fifty (50) stakeholders who participated in and/or observed the DEMO progression were very positive and encouraging, two major areas of further improvements - system integration and web application enhancement - were identified in the post-DEMO evaluation. The principal purpose of the MiniDemo described in this report was to verify these two specific improvements. The MiniDemo was conducted on August 28, 2009. In terms of system integration, a hybrid communication interface - combining the RFID item-monitoring features and a commercial vehicle tracking system by Qualcomm - was developed and implemented. In the MiniDemo, the new integrated system worked well in reporting tag status and vehicle location accurately and promptly. There was no incompatibility of components. The robust commercial communication gear, as expected, helped improve system reliability. The MiniDemo confirmed that system

  14. Report on a 2009 mini-demonstration of the ARG-US Radio Frequency Identification (RFID) system in transportation.

    Energy Technology Data Exchange (ETDEWEB)

    Tsai, H.; Chen, K.; Jusko, M.; Craig, B.; Liu, Y.; Decision and Information Sciences

    2009-11-23

    The Packaging Certification Program (PCP) of the U.S. Department of Energy (DOE) Environmental Management (EM), Office of Packaging and Transportation (EM-14), has developed a radio frequency identification (RFID) tracking and monitoring system for the management of nuclear materials during storage and transportation. The system, developed by the PCP team at Argonne National Laboratory, consists of hardware (Mk-series sensor tags, fixed and handheld readers, form factor for multiple drum types, seal integrity sensors, and enhanced battery management), software (application programming interface, ARG-US software for local and remote/web applications, secure server and database management), and cellular/satellite communication interfaces for vehicle tracking and item monitoring during transport. The ability of the above system to provide accurate, real-time tracking and monitoring of the status of multiple, certified containers of nuclear materials has been successfully demonstrated in a week-long, 1,700-mile DEMO performed in April 2008. While the feedback from the approximately fifty (50) stakeholders who participated in and/or observed the DEMO progression were very positive and encouraging, two major areas of further improvements - system integration and web application enhancement - were identified in the post-DEMO evaluation. The principal purpose of the MiniDemo described in this report was to verify these two specific improvements. The MiniDemo was conducted on August 28, 2009. In terms of system integration, a hybrid communication interface - combining the RFID item-monitoring features and a commercial vehicle tracking system by Qualcomm - was developed and implemented. In the MiniDemo, the new integrated system worked well in reporting tag status and vehicle location accurately and promptly. There was no incompatibility of components. The robust commercial communication gear, as expected, helped improve system reliability. The MiniDemo confirmed that system

  15. The Dream Of Becky Brandon Found In Mini Shopaholic

    OpenAIRE

    Ginting, Hetty Meilany

    2013-01-01

    This paper entitled. “The Dream of Becky Brandon Found in Mini Shopaholic”. Novel is one kind prose’s narrative portrays character and presenting and organized series of event of setting. Becky Brandon is the main character . She thinks that being a mother is easy , and his daughter will be a shopping friend for life ! But Minnie is only two years turned out to have a different approach to shopping . She often screamed " Mineee ! " Indiscriminately , creating chaos from Harrods to Harvey Nich...

  16. Mini-columns for Conducting Breakthrough Experiments. Design and Construction

    Energy Technology Data Exchange (ETDEWEB)

    Dittrich, Timothy M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Reimus, Paul William [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Ware, Stuart Douglas [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-06-11

    Experiments with moderately and strongly sorbing radionuclides (i.e., U, Cs, Am) have shown that sorption between experimental solutions and traditional column materials must be accounted for to accurately determine stationary phase or porous media sorption properties (i.e., sorption site density, sorption site reaction rate coefficients, and partition coefficients or Kd values). This report details the materials and construction of mini-columns for use in breakthrough columns to allow for accurate measurement and modeling of sorption parameters. Material selection, construction techniques, wet packing of columns, tubing connections, and lessons learned are addressed.

  17. Efficacy of biofeedback therapy via a mini wireless device on sleep bruxism contrasted with occlusal splint: a pilot study

    Science.gov (United States)

    Gu, WeiPing; Yang, Jie; Zhang, FeiMin; Yin, XinMin; Wei, XiaoLong; Wang, Chen

    2015-01-01

    Abstract The putative causes of bruxism are multifactorial and there are no definite measures for bruxism management. The aim of this study was to evaluate the efficacy of biofeedback therapy on sleep bruxism, compared with occlusal splint. Twenty-four volunteers with sleep bruxism were divided into two groups: the GTB group that were treated with biofeedback therapy (n  = 12) and the GTO group that were treated with occlusal splint (n  = 12). A mini pressure sensor integrated with a monitoring circuit by use of a maxillary biofeedback splint was fabricated. To foster the relaxation of the masticatory muscles and the nervous system, the wireless device received signals from bruxism events and vibrations alerted the bruxer when the threshold was exceeded. Total episodes and average duration of bruxism events during 8 hours of sleep were analyzed with the monitoring program (TRMY1.0). After 6 and 12 weeks, the episodes (P  =  0.001) and duration (P 0.05). Furthermore, the episodes had significant differences between the GTB group and the GTO group after the same period of treatment (P  =  0.000). The results suggest that biofeedback therapy may be an effective and convenient measure for mild bruxers, when compared with occlusal splint therapy. The mini wireless biofeedback method may be of value for the diagnosis and management of bruxism in the future. PMID:25859272

  18. The role of electrocardiogram in the diagnosis of dextrocardia with mirror image atrial arrangement and ventricular position in a young adult Nigerian in Ile-Ife: a case report.

    Science.gov (United States)

    Ogunlade, Oluwadare; Ayoka, Abiodun O; Akomolafe, Rufus O; Akinsomisoye, Olumide S; Irinoye, Adedayo I; Ajao, Adewale; Asafa, Muritala A

    2015-09-28

    Dextrocardia with situs inversus is a rare congenital disease. In patients with this condition, the heart is presented as a mirror image of itself with its apex pointing to the right. The pulmonary and abdominal anatomies are reversed. Dextrocardia with situs inversus occurs at birth but its diagnosis may be in adulthood. This case advances knowledge by graphically describing the unusual electrocardiographic features of dextrocardia in a young adult. We report a case of a 22-year-old Nigerian man of Yoruba ethnicity who presented himself for preadmission medical test. He had a standard 12-lead electrocardiogram which revealed uncommon features: inversion of P waves in leads I, aVL and aVR; dominantly negative QRS waves in leads I, V1 to V6; reverse R wave progression in chest leads; low voltage in V4 to V6; extreme QRS axis; flattened T waves in V4 to V6 and aVR; and inverted T waves in lead I and aVL. An electrocardiogram diagnosis of dextrocardia was made. The differential diagnosis considered was right ventricular hypertrophy. A cardiovascular examination showed pulse rate of 70 beats per minute, blood pressure of 119/62mmHg, visible cardiac impulse at right precordium, apex beat was located at his fifth right intercostal space mid-clavicular line. A chest X-ray (posterior anterior view) including upper abdomen showed dextrocardia; his aortic arch was located on the right. His stomach bubble was located below his right hemidiaphragm. His trachea was slightly deviated to the left. The findings in his lung fields were not remarkable. Abdominopelvic ultrasonography showed that right-sided intra-abdominal organs (liver, gallbladder) were located on the left while left-sided organs (stomach, spleen) were located on the right. His abdominal aorta was on the right while his inferior vena cava was located on the left. A diagnosis of dextrocardia with situs inversus was made ultrasonographically. A properly interpreted electrocardiogram was useful in suspecting the

  19. Negative ion beam characterisation in BATMAN by mini-STRIKE: Improved design and new measurements

    Science.gov (United States)

    Serianni, G.; Bonomo, F.; Brombin, M.; Cervaro, V.; Chitarin, G.; Cristofaro, S.; Delogu, R.; De Muri, M.; Fasolo, D.; Fonnesu, N.; Franchin, L.; Franzen, P.; Ghiraldelli, R.; Molon, F.; Muraro, A.; Pasqualotto, R.; Ruf, B.; Schiesko, L.; Tollin, M.; Veltri, P.

    2015-04-01

    The ITER project requires additional heating provided by two injectors of neutral beams resulting from the neutralisation of accelerated negative ions. To study and optimise negative ion production, the SPIDER test facility (particle energy 100keV; beam current 50A) is under construction in Padova, with the aim of testing beam characteristics and to verify the source proper operation. The SPIDER beam will be characterised by the instrumented calorimeter STRIKE, whose main components are one-directional carbon fibre carbon composite tiles. Some prototype tiles have been employed in 2012 as a small-scale version (mini-STRIKE) of the entire system to investigate the features of the beam from BATMAN at IPP-Garching. As the BATMAN beamlets are superposed at the measurement position, about 1m from the grounded grid, an actively cooled copper mask is located in front of the tiles; holes in the mask create an artificial beamlet structure. Recently the mini-STRIKE has been updated, taking into account the results obtained in the first campaign. In particular the spatial resolution of the system has been improved by increasing the number of the copper mask holes. Moreover a custom measurement system has been realized for the thermocouple signals and employed in BATMAN in view of its use in SPIDER. The present contribution gives a description of the new design of the system as well as of the thermocouple measurements system and its field test. A new series of measurements has been carried out in BATMAN. The BATMAN beam characterisation in different experimental conditions is presented.

  20. Negative ion beam characterisation in BATMAN by mini-STRIKE: Improved design and new measurements

    International Nuclear Information System (INIS)

    Serianni, G.; Brombin, M.; Cervaro, V.; Chitarin, G.; Delogu, R.; Fasolo, D.; Fonnesu, N.; Franchin, L.; Ghiraldelli, R.; Molon, F.; Pasqualotto, R.; Tollin, M.; Veltri, P.; Bonomo, F.; Cristofaro, S.; De Muri, M.; Franzen, P.; Ruf, B.; Schiesko, L.; Muraro, A.

    2015-01-01

    The ITER project requires additional heating provided by two injectors of neutral beams resulting from the neutralisation of accelerated negative ions. To study and optimise negative ion production, the SPIDER test facility (particle energy 100keV; beam current 50A) is under construction in Padova, with the aim of testing beam characteristics and to verify the source proper operation. The SPIDER beam will be characterised by the instrumented calorimeter STRIKE, whose main components are one-directional carbon fibre carbon composite tiles. Some prototype tiles have been employed in 2012 as a small-scale version (mini-STRIKE) of the entire system to investigate the features of the beam from BATMAN at IPP-Garching. As the BATMAN beamlets are superposed at the measurement position, about 1m from the grounded grid, an actively cooled copper mask is located in front of the tiles; holes in the mask create an artificial beamlet structure. Recently the mini-STRIKE has been updated, taking into account the results obtained in the first campaign. In particular the spatial resolution of the system has been improved by increasing the number of the copper mask holes. Moreover a custom measurement system has been realized for the thermocouple signals and employed in BATMAN in view of its use in SPIDER. The present contribution gives a description of the new design of the system as well as of the thermocouple measurements system and its field test. A new series of measurements has been carried out in BATMAN. The BATMAN beam characterisation in different experimental conditions is presented

  1. Omnidirectional configuration and control approach on mini heavy loaded forklift autonomous guided vehicle

    Directory of Open Access Journals (Sweden)

    Adam Norsharimie

    2017-01-01

    Full Text Available This paper presents the omnidirectional configuration and control approach on Mini Heavy Loaded Forklift Autonomous Guided Vehicle (MHeLFAGV for flexibility maneuverability in confine and narrow area. The issue in turning motion for nonholonomic vehicle in confine area becoming a motivation in MHeLFAGV design to provide holonomic vehicle with flexible movement. Therefore an omni-wheeled named Mecanum wheel has been configured in this vehicle design as well as omnidirectional control algorithm. MHeLFAGV system is developed with collaboration and inspired from Vacuumshmelze (M Sdn. Bhd. Pekan, Pahang in order to have a customized mini forklift that able to work in a very confined warehouse (170cm × 270cm square with heavy payload in a range of 20-200kg. In electronics control design, two stages of controller boards are developed namely as Board 1 and 2 that specifically for movement controller board and monitoring controller board respectively. In addition separate module of left, right, forward, backward, diagonal and zigzagging movement is developed as embedded modules for MHeLFAGV system’s control architecture. A few experiments are done to verify the algorithm for each omnidirectional movement of MHeLFAGV system in the wide area. The waypoint of MHeLFAGV movement is plotted using Global Positioning System (GPS as well as a digital compass by mapping the longitude and latitude of the vehicle. There are slightly different between the targeted movements with recorded data since Mecanum wheeled affected by the uneven surface of the landscape. The experiment is also further on moving in confine are on the actual targeted warehouse.

  2. Probing of miniPEGγ-PNA-DNA Hybrid Duplex Stability with AFM Force Spectroscopy.

    Science.gov (United States)

    Dutta, Samrat; Armitage, Bruce A; Lyubchenko, Yuri L

    2016-03-15

    Peptide nucleic acids (PNA) are synthetic polymers, the neutral peptide backbone of which provides elevated stability to PNA-PNA and PNA-DNA hybrid duplexes. It was demonstrated that incorporation of diethylene glycol (miniPEG) at the γ position of the peptide backbone increased the thermal stability of the hybrid duplexes (Sahu, B. et al. J. Org. Chem. 2011, 76, 5614-5627). Here, we applied atomic force microscopy (AFM) based single molecule force spectroscopy and dynamic force spectroscopy (DFS) to test the strength and stability of the hybrid 10 bp duplex. This hybrid duplex consisted of miniPEGγ-PNA and DNA of the same length (γ(MP)PNA-DNA), which we compared to a DNA duplex with a homologous sequence. AFM force spectroscopy data obtained at the same conditions showed that the γ(MP)PNA-DNA hybrid is more stable than the DNA counterpart, 65 ± 15 pN vs 47 ± 15 pN, respectively. The DFS measurements performed in a range of pulling speeds analyzed in the framework of the Bell-Evans approach yielded a dissociation constant, koff ≈ 0.030 ± 0.01 s⁻¹ for γ(MP)PNA-DNA hybrid duplex vs 0.375 ± 0.18 s⁻¹ for the DNA-DNA duplex suggesting that the hybrid duplex is much more stable. Correlating the high affinity of γ(MP)PNA-DNA to slow dissociation kinetics is consistent with prior bulk characterization by surface plasmon resonance. Given the growing interest in γ(MP)PNA as well as other synthetic DNA analogues, the use of single molecule experiments along with computational analysis of force spectroscopy data will provide direct characterization of various modifications as well as higher order structures such as triplexes and quadruplexes.

  3. Parasitic infections on the shore of Lake Victoria (East Africa) detected by Mini-FLOTAC and standard techniques.

    Science.gov (United States)

    Barda, Beatrice; Ianniello, Davide; Zepheryne, Henry; Rinaldi, Laura; Cringoli, Giuseppe; Burioni, Roberto; Albonico, Marco

    2014-09-01

    Helminths and protozoa infections pose a great burden especially in developing countries, due to morbidity caused by both acute and chronic infection. The aim of our survey was to analyze the intestinal parasitic burden in communities from Mwanza region, Tanzania. Subjects (n=251) from four villages on the South of Lake Victoria have been analyzed for intestinal parasites with direct smear (DS), formol-ether concentration method (FECM) and the newly developed Mini-FLOTAC technique; urinary schistosomiasis was also assessed in a subsample (n=151); symptoms were registered and correlation between clinic and infections was calculated by chi-squared test and logistical regression. Out of the subjects screened for intestinal and for urinary parasites, 87% (218/251) were found positive for any infection, 69% (174/251) carried a helminthic and 67% (167/251) a protozoan infection, almost half of them had a double or triple infection. The most common helminths were hookworms, followed by Schistosoma mansoni and Schistosoma haematobium. Among protozoa, the most common was Entamoeba coli followed by Entamoeba histolytica/dispar and Giardia intestinalis. Mini-FLOTAC detected a number of helminth infections (61.7%) higher than FECM (38.6%) and DS (17.9%). Some positive associations with abdominal symptoms were found and previous treatment was negatively correlated with infection. Despite the limited size of the examined population the current study indicates a high prevalence of intestinal parasitic infection in Bukumbi area, Tanzania, and Mini-FLOTAC showed to be a promising diagnostic tool for helminth infections. This high parasitic burden calls for starting a regular deworming programme and other preventive interventions in schools and in the community. Copyright © 2014 Elsevier B.V. All rights reserved.

  4. Mini-grid for sustainable integrated coastal development

    International Nuclear Information System (INIS)

    Bala, B.K.; Islam, M.M.

    2005-01-01

    Power grid cannot reach everywhere. Yet there are alternatives. Renewable energy can offer an ideal source of electricity for the communities far from a grid- on an island, or other isolated situations. Design and economics of a solar-diesel hybrid mini-grid system for 132 families in an isolated island-Sandwip are presented. The electrical load is considered based on the local needs and the electrical load demand is 20 kWh. The sizing of the hybrid system consists of 31 solar modules, 10 number of 24 V batteries, 2 Inverters having a total capacity of 24 kW, 24 V DC/220 V AC. A diesel generator set of 10 kW capacity is selected for back up during shortfall. The life cycle cost (LCC) is estimated and LCC is found to be Tk.15.51 / kWh compared to electricity price of Tk.4.00/kWh. Finally, the sustainability of solar-diesel hybrid mini-grid for an isolated island -Sandwip is discussed. (author)

  5. Mini-beam collimator applications at the Advanced Photon Source

    Energy Technology Data Exchange (ETDEWEB)

    Xu Shenglan, E-mail: sxu@anl.gov [GM/CA CAT, Biosciences Division, Argonne National Laboratory, Argonne, IL 60439 (United States); Keefe, Lisa J.; Mulichak, Anne [IMCA CAT, Argonne National Laboratory, Argonne, IL 60439 (United States); Yan Lifen; Alp, Ercan E.; Zhao Jiyong [X-ray Sciences Division, Argonne National Laboratory, Argonne, IL 60439 (United States); Fischetti, Robert F. [GM/CA CAT, Biosciences Division, Argonne National Laboratory, Argonne, IL 60439 (United States)

    2011-09-01

    In 2007, the General Medicine and Cancer Institutes Collaborative Access Team (GM/CA CAT, Sector 23, Advanced Photon Source) began providing mini-beam collimators to its users. These collimators contained individual, 5- or 10-{mu}m pinholes and were rapidly exchangeable, thereby allowing users to tailor the beam size to their experimental needs. The use of these collimators provided a reduction in background noise, and thus improved the signal-to-noise ratio . Recent improvements in the collimator design include construction of the device from a monolithic piece of molybdenum with multiple pinholes mounted inside . This allows users to select from various size options from within the beamline control software without the realignment that was previously necessary. In addition, a new, 20-{mu}m pinhole has been added to create a 'quad-collimator', resulting in greater flexibility for the users. The mini-beam collimator is now available at multiple crystallographic beamlines and also is a part of the first Moessbauer Microscopic system at sector 3-ID.

  6. Mini-beam collimator applications at the Advanced Photon Source

    International Nuclear Information System (INIS)

    Xu Shenglan; Keefe, Lisa J.; Mulichak, Anne; Yan Lifen; Alp, Ercan E.; Zhao Jiyong; Fischetti, Robert F.

    2011-01-01

    In 2007, the General Medicine and Cancer Institutes Collaborative Access Team (GM/CA CAT, Sector 23, Advanced Photon Source) began providing mini-beam collimators to its users. These collimators contained individual, 5- or 10-μm pinholes and were rapidly exchangeable, thereby allowing users to tailor the beam size to their experimental needs. The use of these collimators provided a reduction in background noise, and thus improved the signal-to-noise ratio . Recent improvements in the collimator design include construction of the device from a monolithic piece of molybdenum with multiple pinholes mounted inside . This allows users to select from various size options from within the beamline control software without the realignment that was previously necessary. In addition, a new, 20-μm pinhole has been added to create a 'quad-collimator', resulting in greater flexibility for the users. The mini-beam collimator is now available at multiple crystallographic beamlines and also is a part of the first Moessbauer Microscopic system at sector 3-ID.

  7. Fuel performance analysis for the HAMP-1 mini plate test

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Byoung Jin; Tahka, Y. W.; Yim, J. S.; Lee, B. H. [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    U-7wt%Mo/Al- 5wt%Si dispersion fuel with 8gU/cm{sup 3} is chosen to achieve more efficiency and higher performance than the conventional U{sub 3}Si{sub 2} fuel. As part of the fuel qualification program for the KiJang research reactor (KJRR), three irradiation tests with mini-plates are on the way at the High-flux Advanced Neutron Application Reactor (HANARO). The first test among three HANARO Mini-Plate Irradiation tests (HAMP-1, 2, 3) has completed. PLATE code has been initially developed to analyze the thermal performance of high density U-Mo/Al dispersion fuel plates during irradiation [1]. We upgraded the PLATE code with the latest irradiation results which were implemented by corrosion, thermal conductivity and swelling model. Fuel performance analysis for HAMP-1 was conducted with updated PLATE. This paper presents results of performance evaluation of the HAMP-1. Maximum fuel temperature was obtained 136 .deg., which is far below the preset limit of 200 .deg. for the irradiation test. The meat swelling and corrosion thickness was also confirmed that the developed fuel would behave as anticipated.

  8. Cooling down MiniGRAIL to milli-Kelvin temperatures

    International Nuclear Information System (INIS)

    Waard, A de; Gottardi, L; Bassan, M; Coccia, E; Fafone, V; Flokstra, J; Karbalai-Sadegh, A; Minenkov, Y; Moleti, A; Pallottino, G V; Podt, M; Pors, B J; Reincke, W; Rocchi, A; Shumack, A; Srinivas, S; Visco, M; Frossati, G

    2004-01-01

    The latest developments in the construction of the ultra-cryogenic spherical detector MiniGRAIL are presented. The room temperature part of the vibration isolation system was improved and provided with an attenuation of about 60 dB around 3 kHz. The transfer function of the cryogenic stages gave about 20 dB per stage, at the resonant frequency of the sphere. The latest results of three cryogenic tests at ultra-low temperature of the spherical detector MiniGRAIL, using several thermal anchorings, are presented. Minimum temperatures of 20 mK on the mixing chamber of the dilution refrigerator and 79 mK on the surface of the sphere were reached. During the last cool down, two capacitive transducers were mounted on the sphere. The first was coupled to a room temperature FET amplifier and the second to a transformer and a double stage SQUID amplifier. Unfortunately the SQUID did not work, so only the first resonator could be used. An equivalent temperature of about 20 K was measured during an acquisition run of 7 h, using the first transducer corresponding to the FET white noise

  9. Micro and mini hydroelectric power assessment in Uruguay

    International Nuclear Information System (INIS)

    Nunes, V.; Genta, J.L.

    1996-01-01

    The School of Engineering in Montevideo, Uruguay, within the framework of Agreements made with the National Utility, has carried out an assessment of the potential and studies of the feasibility of the use of renewable energy for the generation of electrical power, both at the industrial level and the autonomous level for rural electrification. Original assessment methodologies were developed, including calculation tools which allow, for example, to analyze historical meteorological data, to calculate the available energy in different kinds of energy generators and also to stimulate the operation and design of autonomous systems with established load requirements and service quality. At the micro and mini hydropower assessment, the main role was placed on the census of potential users and the preliminary analysis of the representative places for the different technical solutions adequate to the variety of topographic conditions and load requirements. For power above 1 MW and up to 5 MW, the generating potential was assessed all over the country. If power lower than 1 MW or lower than 100kW (mini and micro) is considered, the information available in maps with contour lines, including in those of a 1:50,000 scale, is not enough to identify the most adequate places. Instead, knowledge of the place is indispensable in these cases. A preliminary plan of several installations was worked out. (Author)

  10. A multiplex PCR mini-barcode assay to identify processed shark products in the global trade.

    Directory of Open Access Journals (Sweden)

    Diego Cardeñosa

    Full Text Available Protecting sharks from overexploitation has become global priority after widespread population declines have occurred. Tracking catches and trade on a species-specific basis has proven challenging, in part due to difficulties in identifying processed shark products such as fins, meat, and liver oil. This has hindered efforts to implement regulations aimed at promoting sustainable use of commercially important species and protection of imperiled species. Genetic approaches to identify shark products exist but are typically based on sequencing or amplifying large DNA regions and may fail to work on heavily processed products in which DNA is degraded. Here, we describe a novel multiplex PCR mini-barcode assay based on two short fragments of the cytochrome oxidase I (COI gene. This assay can identify to species all sharks currently listed on the Convention of International Trade of Endangered Species (CITES and most shark species present in the international trade. It achieves species diagnosis based on a single PCR and one to two downstream DNA sequencing reactions. The assay is capable of identifying highly processed shark products including fins, cooked shark fin soup, and skin-care products containing liver oil. This is a straightforward and reliable identification method for data collection and enforcement of regulations implemented for certain species at all governance levels.

  11. Mini outbreak of Kaposi′s varicelliform eruption in skin ward: A study of five cases

    Directory of Open Access Journals (Sweden)

    Rao GRR

    2007-01-01

    Full Text Available Background: Kaposi`s varicelliform eruption (KVE represents widespread cutaneous herpes simplex virus (HSV infection in patients with preexisting dermatoses. Occasionally, this infection can present as a nosocomial infection in skin wards, if adequate bed-spacing and barrier nursing methods are not followed. We are reporting five cases of KVE; four cases acquired the infection in a makeshift ward after admission of the first case in May 2005, due to the renovation work of the regular skin ward. Aim: The purpose of this study is to create clinical awareness about this uncommon dermatologic entity and to stress upon the importance of bed-spacing and barrier nursing in skin wards. Methods: Five cases of KVE, three females and two males with different primary dermatoses (pemphigus foliaceus - one, pemphigus vulgaris - two, paraneoplastic pemphigus - one and toxic epidemal necrolysis - one were included in this study. Diagnosis was made clinically and supported with Tzanck smear and HSV serology. All the cases were treated with oral acyclovir. Results: Four out of five cases of KVE recovered with treatment, one case of extensive pemphigus vulgaris with KVE succumbed to death. Conclusion: Mini outbreaks of KVE can occur in skin wards with inadequate bed-spacing and overcrowding of patients. Therefore adequate bed-spacing, barrier nursing and isolation of suspected cases are mandatory to prevent such life-threatening infections.

  12. Cognitive Deficits in Healthy Elderly Population With "Normal" Scores on the Mini-Mental State Examination.

    Science.gov (United States)

    Votruba, Kristen L; Persad, Carol; Giordani, Bruno

    2016-05-01

    This study investigated whether healthy older adults with Mini-Mental State Examination (MMSE) scores above 23 exhibit cognitive impairment on neuropsychological tests. Participants completed the MMSE and a neuropsychological battery including tests of 10 domains. Results were compared to published normative data. On neuropsychological testing, participants performed well on measures of naming and recall but showed mild to moderate impairment in working memory and processing speed and marked impairment in inhibition, sustained attention, and executive functioning. Almost everyone (91%) scored at least 1 standard deviation (SD) below the mean in at least 1 domain. The median number of domains in which individuals scored below 1 SD was 3.0 of 10.0, whereas over 21% scored below 1 SD in 5 domains or more. With the strictest of definitions for impairment, 20% of this population scored below 2.0 SDs below the norm in at least 2 domains, a necessary condition for a diagnosis of dementia. The finding that cognitive impairment, particularly in attention and executive functioning, is found in healthy older persons who perform well on the MMSE has clinical and research implications in terms of emphasizing normal variability in performance and early identification of possible impairment. © The Author(s) 2016.

  13. Social media use of older adults: a mini-review.

    Science.gov (United States)

    Leist, Anja K

    2013-01-01

    Maintaining social relationships has been defined as a core element of aging well. With a considerable amount of older adults living alone, social media provides the possibility to engage in meaningful social contact, e.g. by joining online social networks and online discussion forums. The review encompasses current knowledge of prerequisites in social media use of older adults such as functional capacity, information and communications technology-related knowledge, and favorable attitudes towards social media. Then, the potential of social media use for clinical practice and possible negative consequences are outlined. Literature on social media use from a gerontological perspective was reviewed in July and August 2012. Online communities are suitable for providing and receiving social support when confronted with a difficult life situation, regardless of geographical location or time. From a practitioner's perspective, social media can be used to advance health-related knowledge such as information on prevention, diagnosis, and treatment of specific conditions and disorders. Further positive consequences have been shown to be overcoming loneliness, relieving stress, and raising feelings of control and self-efficacy. Possible negative consequences could be misuse of personal data as well as the distribution and uncritical adoption of potentially harmful information via online communities. The potential of social media in clinical practice is reflected in a wide range of intervention possibilities for older adults. However, with the rise of social media, new threats emerge for older adults as well. Copyright © 2013 S. Karger AG, Basel.

  14. Position Information

    Data.gov (United States)

    Social Security Administration — The Position Information Data Asset provides the ability to search for active SSA position descriptions using various search criteria. An individual may search by PD...

  15. Psychometric evaluation of a Dutch version of the Mini PAS-ADD for assessing psychiatric disorders in adults with different levels of intellectual disability.

    Science.gov (United States)

    Janssen, R; Maes, B

    2013-08-01

    People with intellectual disabilities (ID) have an increased vulnerability to develop psychiatric problems. Moreover, the early recognition and the accurate diagnosis of psychiatric disorders in the population of persons with ID are challenging. A Dutch version of the Mini PAS-ADD, which is a screening instrument for identification of mental health problems in people with ID, was evaluated in terms of internal consistency, interinformant reliability, item grouping and criterion validity based on a large-scale random sample (n = 377) and a clinical sample (n = 99) of adults with ID. The Dutch version of the Mini PAS-ADD showed moderate internal consistency, and moderate concordance among informants. Both aspects of the reliability were comparable for different levels of ID. A factor analysis largely confirmed the scale structure. Concurrent validity with the Reiss Screen for Maladaptive Behavior was high for the Depression, Psychosis and Autism scale. The outcome of the criterion-validity analysis indicated high specificity. The sensitivity for specific psychiatric disorders by the corresponding scales was moderate, but the general sensitivity for the presence of psychopathology on the basis of any of the scales was satisfying. The present research reconfirmed the use of the Mini PAS-ADD as a primary screening device for the identification of mental health problems among people with ID. © 2012 The Authors. Journal of Intellectual Disability Research © 2012 John Wiley & Sons Ltd, MENCAP & IASSID.

  16. [The "Mini-ICF-Rating for Mental Disorders (Mini-ICF-P)". A short instrument for the assessment of disabilities in mental disorders].

    Science.gov (United States)

    Linden, M; Baron, S

    2005-06-01

    Supplementary to the description of diseases at symptom level, the International Classification of Functioning, Disability and Health (ICF), edited by the WHO, for the first time enables a systematic description also at the level of disabilities and impairments. The Mini-ICF-Rating for Mental Disorders (Mini-ICF-P) is a short observer rating instrument for the assessment of disabilities, especially with regard to occupational functioning. The Mini-ICF-P was first evaluated empirically in 125 patients of a Department of Behavioural Medicine and Psychosomatics. Parallel-test reliability was r = 0.59. Correlates were found with cognitive and motivational variables and duration of sick leave from work. In summary, the Mini-ICF-P is a quick and practicable instrument.

  17. Mesialização de molares com ancoragem em mini-implantes Mesial movement of molars with mini-implants anchorage

    Directory of Open Access Journals (Sweden)

    Marcos Janson

    2008-10-01

    Full Text Available INTRODUÇÃO: é muito comum, na rotina do consultório odontológico, especialmente em Ortodontia, o paciente, após avaliar o plano de tratamento proposto, questionar sobre a possibilidade de fechamento de espaços presentes, ocasionados pela perda de dentes permanentes. O ortodontista, frente a essa questão, tem que avaliar diversos fatores, tais como a má oclusão presente, a integridade do osso e das raízes, o tempo de tratamento e a geometria do posicionamento dentário, que é o que permite avaliar se, com o fechamento dos espaços e, conseqüentemente, a perda de ancoragem dos segmentos anteriores, a finalização estará de acordo com os ideais que regem a especialidade. Com o advento dos mini-implantes, as possibilidades desta abordagem terapêutica aumentaram, pois o efeito adverso da perda de ancoragem pode ser eliminado e, com isso, o paciente pode ser beneficiado. No entanto, os outros fatores envolvidos, assim como a mecânica do movimento, requerem especial atenção. OBJETIVOS: no presente artigo serão abordados os fatores envolvidos neste tipo de tratamento, o raciocínio na tomada de decisões e os detalhes importantes que devem ser observados durante a condução da mecânica, ilustrados com casos clínicos.INTRODUCTION: It's routine, especially at the orthodontic office, the patient, after the assessment of the proposed treatment plan, answer about the possibility of closing their edentulous spaces caused by missed permanent teeth. In these situations, several factors must be evaluated, like the present malocclusion, the bone and roots integrity, the treatment time and the geometry of teeth positioning, that is what permits to assess if the loss of anchorage from the anterior segments, during the space closure, would permit the occlusion to end within the orthodontic ideals. With the mini-implants, the possibilities of this therapeutic approach have been improved, since the adverse effects are eliminated with the

  18. Position paper

    DEFF Research Database (Denmark)

    van den Heuvel-Eibrink, Marry M; Hol, Janna A; Pritchard-Jones, Kathy

    2017-01-01

    The Renal Tumour Study Group of the International Society of Paediatric Oncology (SIOP-RTSG) has developed a new protocol for the diagnosis and treatment of childhood renal tumours, the UMBRELLA SIOP-RTSG 2016 (the UMBRELLA protocol), to continue international collaboration in the treatment of ch...

  19. Position paper

    DEFF Research Database (Denmark)

    Christiansen, Peer; Vejborg, Ilse Merete Munk; Kroman, Niels Thorndahl

    2014-01-01

    BACKGROUND: During the last decades the diagnosis, treatment, and prognosis of breast cancer have changed and improved in Denmark. The first mammography screening programme started in 1991. However, for many years only about 20% of Danish women aged 50-69 were offered screening. The national roll...

  20. Differential diagnosis

    Directory of Open Access Journals (Sweden)

    Abdallah Adra

    2016-09-01

    Full Text Available Abnormal uterine bleeding may be acute or chronic accounting for up to 30% of outpatient visits to gynecologists. Hyperprolactinemia is one of the most common endocrine disorders associated with ovulatory dysfunction that results in menstrual irregularities. Prior to initiating treatment, the various causes (physiologic, pathologic, pharmacologic, or idiopathic of hyperprolactinemia must be elucidated. Prolactin is a stress hormone that increases in response to stressful conditions; therefore, while collecting samples it is necessary to reduce venipuncture stress. A thorough patient history and physical examination will help to identify the cause and to direct therapy. Imaging results must always be assessed along with a patient’s clinical history and biochemical parameters when a pituitary tumor is suspected. Magnetic resonance imaging is the method of choice for the diagnosis of microprolactinomas and macroprolactinomas in both initial assessment and follow-up. Several drugs may cause a significant increase in serum prolactin concentration. If clinically feasible, the drug should be discontinued; if this is not possible, it should be substituted with a drug of similar action that does not cause hyperprolactinemia. Prolactinomas are the most common cause of pituitary adenomas affecting women of fertile age leading to significant elevations in prolactin that warrant treatment. Idiopathic hyperprolactinemia may be observed in the presence of elevated serum prolactin levels and in the absence of any other recognized cause of increased prolactin secretion. Dopamine agonists are the mainstay of therapy in prolactinomas and symptomatic idiopathic hyperprolactinemia because they normalize serum prolactin, effectively shrink prolactinomas and normalize gonadal function (i.e. menstruation.

  1. Positive Psychology

    Science.gov (United States)

    Peterson, Christopher

    2009-01-01

    Positive psychology is a deliberate correction to the focus of psychology on problems. Positive psychology does not deny the difficulties that people may experience but does suggest that sole attention to disorder leads to an incomplete view of the human condition. Positive psychologists concern themselves with four major topics: (1) positive…

  2. A multi-level modeling approach examining PTSD symptom reduction during prolonged exposure therapy: moderating effects of number of trauma types experienced, having an HIV-related index trauma, and years since HIV diagnosis among HIV-positive adults.

    Science.gov (United States)

    Junglen, Angela G; Smith, Brian C; Coleman, Jennifer A; Pacella, Maria L; Boarts, Jessica M; Jones, Tracy; Feeny, Norah C; Ciesla, Jeffrey A; Delahanty, Douglas L

    2017-11-01

    People living with HIV (PLWH) have extensive interpersonal trauma histories and higher rates of posttraumatic stress disorder (PTSD) than the general population. Prolonged exposure (PE) therapy is efficacious in reducing PTSD across a variety of trauma samples; however, research has not examined factors that influence how PTSD symptoms change during PE for PLWH. Using multi-level modeling, we examined the potential moderating effect of number of previous trauma types experienced, whether the index trauma was HIV-related or not, and years since HIV diagnosis on PTSD symptom reduction during a 10-session PE protocol in a sample of 51 PLWH. In general, PTSD symptoms decreased linearly throughout the PE sessions. Experiencing more previous types of traumatic events was associated with a slower rate of PTSD symptom change. In addition, LOCF analyses found that participants with a non-HIV-related versus HIV-related index trauma had a slower rate of change for PTSD symptoms over the course of PE. However, analyses of raw data decreased this finding to marginal. Years since HIV diagnosis did not impact PTSD symptom change. These results provide a better understanding of how to tailor PE to individual clients and aid clinicians in approximating the rate of symptom alleviation. Specifically, these findings underscore the importance of accounting for trauma history and index trauma type when implementing a treatment plan for PTSD in PLWH.

  3. Gender and Self-Employment: The Role of Mini-Companies

    Science.gov (United States)

    Johansen, Vegard

    2016-01-01

    Purpose: The purpose of this paper is to evaluate to what degree participation in mini-companies impact young women and men with regard to the perceived desirability and perceived feasibility of self-employment. The Company Programme (CP) is the largest mini-company scheme in European secondary school. Design/methodology/approach: The data derived…

  4. Case Study: Mini-Case Studies: Small Infusions of Active Learning for Large-Lecture Courses

    Science.gov (United States)

    Carloye, Lisa

    2017-01-01

    In this article, the author introduces the usage of case studies to be an excellent method for engaging students through stories. The author notes she developed a series of mini-case studies that can be implemented, with a little advance preparation, within a 10- to 15-minute window during lecture. What makes them "mini" case studies?…

  5. The MiniBIOS model (version 1A4) at the RIVM

    NARCIS (Netherlands)

    Uijt de Haag PAM; Laheij GMH

    1993-01-01

    This report is the user's guide of the MiniBIOS model, version 1A4. The model is operational at the Laboratory of Radiation Research of the RIVM. MiniBIOS is a simulation model for calculating the transport of radionuclides in the biosphere and the consequential radiation dose to humans. The

  6. Mini-tablets versus pellets as promising multiparticulate modified release delivery systems for highly soluble drugs.

    Science.gov (United States)

    Gaber, Dina M; Nafee, Noha; Abdallah, Osama Y

    2015-07-05

    Whether mini-tablets (tablets, diameters ≤6mm) belong to single- or multiple-unit dosage forms is still questionable. Accordingly, Pharmacopoeial evaluation procedures for mini-tablets are lacking. In this study, the aforementioned points were discussed. Moreover, their potential for oral controlled delivery was assessed. The antidepressant venlafaxine hydrochloride (Vx), a highly soluble drug undergoing first pass effect, low bioavailability and short half-life was selected as a challenging payload. In an attempt to weigh up mini-tablets versus pellets as multiparticulate carriers, Vx-loaded mini-tablets were compared to formulated pellets of the same composition and the innovator Effexor(®)XR pellets. Formulations were prepared using various polymer hydrogels in the core and ethyl cellulose film coating with increasing thickness. Mini-tablets (diameter 2mm) showed extended Vx release (<60%, 8h). Indeed, release profiles comparable to Effexor(®)XR pellets were obtained. Remarkably higher coating thickness was required for pellets to provide equivalent retardation. Ethyl cellulose in the core ensured faster release due to polymer migration to the surface and pore formation in the coat. mini-tablets showed higher stability to pellets upon storage. Industrially speaking, mini-tablets proved to be superior to pellets in terms of manufacturing, product quality and economical aspects. Results point out the urgent need for standardized evaluation procedures for mini-tablets. Copyright © 2015. Published by Elsevier B.V.

  7. Two mini-preparation protocols to DNA extraction from plants with ...

    African Journals Online (AJOL)

    Were standardized two previously reported standard plant DNA extraction methods, but improved them on mini preparations to use the samples for population genetic analysis. The combination of CTAB lysis procedure-solvent extraction and DNA column purification (DNeasy plant mini kit modification) enables a faster and ...

  8. Consistência interna da versão em português do Mini-Inventário de Fobia Social (Mini-SPIN Internal consistency of the Portuguese version of the Mini-Social Phobia Inventory (Mini-SPIN

    Directory of Open Access Journals (Sweden)

    Gustavo J. Fonseca D'El Rey

    2007-01-01

    Full Text Available CONTEXTO: A fobia social é um grave transtorno de ansiedade que traz incapacitação e sofrimento. OBJETIVOS: Investigar a consistência interna da versão em português do Mini-Inventário de Fobia Social (Mini-SPIN. MÉTODOS: Foi realizado um estudo da consistência interna do Mini-SPIN em uma amostra de 206 estudantes universitários da cidade de São Paulo, SP. RESULTADOS: A consistência interna do instrumento, analisada pelo coeficiente alfa de Cronbach, foi de 0,81. CONCLUSÕES: Esses achados permitiram concluir que a versão em português do Mini-SPIN exibiu resultados de boa consistência interna, semelhantes aos da versão original em inglês.BACKGROUND: Social phobia is a severe anxiety disorder that brings disability and distress. OBJECTIVES: To investigate the internal consistency of the Portuguese version of the Mini-Social Phobia Inventory (Mini-SPIN. METHODS: We conducted a study of internal consistency of the Mini-SPIN in a sample of 206 college students of the city of São Paulo, SP. RESULTS: The internal consistency of the instrument, analyzed by Cronbach's alpha coefficient, was 0.81. CONCLUSIONS: These findings suggest that the Portuguese version of the Mini-SPIN has a good internal consistency, similar to those obtained with the original English version.

  9. A preliminary study of the mini-mental state examination in a Spanish child population.

    Science.gov (United States)

    Rubial-Alvarez, Sandra; Machado, María-Clara; Sintas, Elena; de Sola, Susana; Böhm, Peter; Peña-Casanova, Jordi

    2007-11-01

    The Mini-Mental State Examination is one of the most widely used screening tests for the adult population in daily neurologic practice. The aim of this study was to describe and to analyze the results of the Mini-Mental State Examination administered to Spanish children and to assess the relationship between Mini-Mental State Examination scores and the child's mental age/intelligence quotient. The study population included 181 children whose ages ranged between 4 and 12 years. The neuropsychologic battery consisted of the Mini-Mental State Examination and Kaufman Brief Intelligence Test. Percentiles were obtained for the Mini-Mental State Examination total score according to age ranges. Performance gradually increased from 4 to 10 years of age when a plateau in the total Mini-Mental State Examination score was reached. At the age of 6 years, results exceeded 24 on average. Pairwise mean comparisons showed statistically significant differences between the age groups (P Mini-Mental State Examination score correlated significantly with the child's chronologic (r = 0.80, P mental (r = 0.76, P Mini-Mental State Examination in a Spanish child population as well as a first step for the assessment of the usefulness of this instrument as a cognitive screening tool for children's development.

  10. [White House Conference on Aging, 1981: Reports of the Mini-Conferences, MCR 1-42.

    Science.gov (United States)

    White House Conference on Aging, Washington, DC.

    This document contains the 42 reports from mini-conferences held in various nationwide locations prior to the 1981 White House Conference on Aging. Each report presents an overview of the topic, descriptions of particular problems, and statements of recommendations, based on the views of mini-conference participants, and made available to the…

  11. Mini-Grids for the Base of the Pyramid Market: A Critical Review

    Directory of Open Access Journals (Sweden)

    Subhes C. Bhattacharyya

    2018-04-01

    Full Text Available The lack of access to electricity of more than 1.1 billion people around the world remains a major developmental challenge and Goal 7 of the Sustainable Development Goals (SDG as well as Sustainable Energy for All (SE4ALL have set a target of universal electrification by 2030. Various studies have identified mini-grid-based electrification as a possible solution. There is a growing body of literature available now that has explored the feasibility, practical application and policy interventions required to support mini-grids. Through a review of available literature, this paper explores whether mini-grids can be a solution for the base of the pyramid (BoP market and the challenges faced in deploying mini-grids in such markets. Interventions to support the mini-grid deployment are also discussed. The paper finds that the mini-grids are targeting the BoP market but the business is not attractive in profitability terms and requires financial support. Lack of regulatory clarity and non-coordinated policies affect the financial viability of projects, which requires careful support. Mini-grid electrification has hardly been embedded in rural development agenda and hence they have not contributed significantly to livelihood generation. Careful realignment of policies, regulatory frameworks and support systems can better support mini-grid deployment in developing countries.

  12. Neutrinos from the NuMI beamline in the MiniBooNE detector

    International Nuclear Information System (INIS)

    Aguilar-Arevalo, Alexis A.

    2006-01-01

    With the startup of the NuMI beamline early in 2005, the MiniBooNE detector has the unique opportunity to be the first user of an off-axis neutrino beam (110 mrad off-axis). MiniBooNE is assembling a rich sample of neutrino interactions from this source

  13. Mini-Digest of Education Statistics, 2008. NCES 2009-021

    Science.gov (United States)

    Snyder, Thomas D.

    2009-01-01

    This publication is the 14th edition of the "Mini-Digest of Education Statistics," a pocket-sized compilation of statistical information covering the broad field of American education from kindergarten through graduate school. The "Mini-Digest" is designed as an easy reference for materials found in much greater detail in the…

  14. Ubiquitous positioning

    CERN Document Server

    Mannings, Robin

    2008-01-01

    This groundbreaking resource offers a practical, in-depth understanding of Ubiquitous Positioning - positioning systems that identify the location and position of people, vehicles and objects in time and space in the digitized networked economy. The future and growth of ubiquitous positioning will be fueled by the convergence of many other areas of technology, from mobile telematics, Internet technology, and location systems, to sensing systems, geographic information systems, and the semantic web. This first-of-its-kind volume explores ubiquitous positioning from a convergence perspective, of

  15. Imaging diagnosis of hepatoma

    International Nuclear Information System (INIS)

    Ashizawa, Tatsuto

    1984-01-01

    Nuclear medicine (NM), ultrasonography (US), and computed tomography (CT) were evaluated as screening methods for hepatoma, and the characteristics of each modality were compared. Qualitative diagnosis of hepatoma by measuring the quantitative time-lapse changes in 67 Ga-citrate accumulation was also investigated. A prospective analysis using the above modalities was conducted for 70 patients with hepatoma, with the following results: sensitivities of NM, US and CT were 91.1% ; 91.8% ; and 96.9% respectively. In comparing the characteristics of the three modalities, however, it was concluded that the combined use of NM and US was recommended for screening, and that CT should be used for more detailed examination of a tumor indicated by NM and/or US. In the diagnosis of hepatoma by 67 Ga-citrate, a sensitivity rate of 73.7% and a specificity rate of 92.5% were obtained, indicating 67 Ga-citrate's considerable significance for qualitative diagnosis of hepatoma. A decision tree was also made for those patients with chronic liver disease in whom positive hepatitis B virus (HBV) infection was detected or in whom serum alpha-fetoprotein (AFP) showed an increasing tendency. (author)

  16. Positioning consumption

    DEFF Research Database (Denmark)

    Halkier, Bente; Keller, Margit

    2014-01-01

    positionings emerges based on empirical examples of research in parent–children consumption. Positionings are flexible discursive fixations of the relationship between the performances of the practitioner, other practitioners, media discourse and consumption activities. The basic positioning types...... are the practice maintenance and the practice change position, with different sorts of adapting in between. Media discourse can become a resource for a resistant position against social control or for an appropriating position in favour of space for action. Regardless of the current relation to a particular media......This article analyses the ways in which media discourses become a part of contested consumption activities. We apply a positioning perspective with practice theory to focus on how practitioners relate to media discourse as a symbolic resource in their everyday practices. A typology of performance...

  17. Why are mini-implants lost: the value of the implantation technique!

    Science.gov (United States)

    Romano, Fabio Lourenço; Consolaro, Alberto

    2015-01-01

    The use of mini-implants have made a major contribution to orthodontic treatment. Demand has aroused scientific curiosity about implant placement procedures and techniques. However, the reasons for instability have not yet been made totally clear. The aim of this article is to establish a relationship between implant placement technique and mini-implant success rates by means of examining the following hypotheses: 1) Sites of poor alveolar bone and little space between roots lead to inadequate implant placement; 2) Different sites require mini-implants of different sizes! Implant size should respect alveolar bone diameter; 3) Properly determining mini-implant placement site provides ease for implant placement and contributes to stability; 4) The more precise the lancing procedures, the better the implant placement technique; 5) Self-drilling does not mean higher pressures; 6) Knowing where implant placement should end decreases the risk of complications and mini-implant loss.

  18. Why are mini-implants lost: The value of the implantation technique!

    Directory of Open Access Journals (Sweden)

    Fabio Lourenço Romano

    2015-02-01

    Full Text Available The use of mini-implants have made a major contribution to orthodontic treatment. Demand has aroused scientific curiosity about implant placement procedures and techniques. However, the reasons for instability have not yet been made totally clear. The aim of this article is to establish a relationship between implant placement technique and mini-implant success rates by means of examining the following hypotheses: 1 Sites of poor alveolar bone and little space between roots lead to inadequate implant placement; 2 Different sites require mini-implants of different sizes! Implant size should respect alveolar bone diameter; 3 Properly determining mini-implant placement site provides ease for implant placement and contributes to stability; 4 The more precise the lancing procedures, the better the implant placement technique; 5 Self-drilling does not mean higher pressures; 6 Knowing where implant placement should end decreases the risk of complications and mini-implant loss.

  19. Psychometric Properties of the Persian Adaptation of Mini-Cog Test in Iranian Older Adults.

    Science.gov (United States)

    Rezaei, Mohammad; Rashedi, Vahid; Lotfi, Gohar; Shirinbayan, Peymaneh; Foroughan, Mahshid

    2018-04-01

    The aim of this study was to assess the psychometric properties of the Mini-Cog in Iranian older adults. It was a cross-sectional study; 50 older people with dementia and 50 without dementia who matched for age, gender, and education entered the study. The diagnostic and statistical manual of mental disorders criteria for dementia were used as gold standard. A battery of scales included the abbreviated mental test score (AMTS), the Geriatric Depression Scale, and the Mini-Cog was performed. Validity and reliability of the Mini-Cog determined using the Pearson product-moment correlation coefficient (Pearson's r), Cronbach's alpha, and Receiver Operating Characteristic (ROC) curve analysis. The Persian version of Mini-Cog showed a good inter-rater reliability ( K = 0.76, p Mini-Cog have an acceptable sensitivity, specificity, and substantial overall agreement with the AMTS.

  20. Review of Strategies and Technologies for Demand-Side Management on Isolated Mini-Grids

    Energy Technology Data Exchange (ETDEWEB)

    Harper, Meg [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2013-03-01

    This review provides an overview of strategies and currently available technologies used for demandside management (DSM) on mini-grids throughout the world. For the purposes of this review, mini-grids are defined as village-scale electricity distribution systems powered by small local generation sources and not connected to a main grid.1 Mini-grids range in size from less than 1 kW to several hundred kW of installed generation capacity and may utilize different generation technologies, such as micro-hydro, biomass gasification, solar, wind, diesel generators, or a hybrid combination of any of these. This review will primarily refer to AC mini-grids, though much of the discussion could apply to DC grids as well. Many mini-grids include energy storage, though some rely solely on real-time generation.

  1. Validity and inter-rater reliability of medio-lateral knee motion observed during a single-limb mini squat

    Directory of Open Access Journals (Sweden)

    Simic Milena

    2010-11-01

    Full Text Available Abstract Background Muscle function may influence the risk of knee injury and outcomes following injury. Clinical tests, such as a single-limb mini squat, resemble conditions of daily life and are easy to administer. Fewer squats per 30 seconds indicate poorer function. However, the quality of movement, such as the medio-lateral knee motion may also be important. The aim was to validate an observational clinical test of assessing the medio-lateral knee motion, using a three-dimensional (3-D motion analysis system. In addition, the inter-rater reliability was evaluated. Methods Twenty-five (17 women non-injured participants (mean age 25.6 years, range 18-37 were included. Visual analysis of the medio-lateral knee motion, scored as knee-over-foot or knee-medial-to-foot by two raters, and 3-D kinematic data were collected simultaneously during a single-limb mini squat. Frontal plane 2-D peak tibial, thigh, and knee varus-valgus angles, and 3-D peak hip internal-external rotation, and knee varus-valgus angles were calculated. Results Ten subjects were scored as having a knee-medial-to-foot position and 15 subjects a knee-over-foot position assessed by visual inspection. In 2-D, the peak tibial angle (mean 89.0 (SE 0.7 vs mean 86.3 (SE 0.4 degrees, p = 0.001 and peak thigh angle (mean 77.4 (SE 1.0 vs mean 81.2 (SE 0.5 degrees, p = 0.001 with respect to the horizontal, indicated that the knee was more medially placed than the ankle and thigh, respectively. Thus, the knee was in more valgus (mean 11.6 (SE 1.5 vs 5.0 (SE 0.8 degrees, p 0.90 and 96 between raters. Conclusions Medio-lateral motion of the knee can reliably be assessed during a single-leg mini-squat. The test is valid in 2-D, while the actual movement, in 3-D, is mainly exhibited as increased internal hip rotation. The single-limb mini squat is feasible and easy to administer in the clinical setting and in research to address lower extremity movement quality.

  2. Mini-mental state examination as a predictor of mortality among older people referred to secondary mental healthcare.

    Science.gov (United States)

    Su, Yu-Ping; Chang, Chin-Kuo; Hayes, Richard D; Perera, Gayan; Broadbent, Matthew; To, David; Hotopf, Matthew; Stewart, Robert

    2014-01-01

    Lower levels of cognitive function have been found to be associated with higher mortality in older people, particularly in dementia, but the association in people with other mental disorders is still inconclusive. Data were analysed from a large mental health case register serving a geographic catchment of 1.23 million residents, and associations were investigated between cognitive function measured by the Mini-Mental State Examination (MMSE) and survival in patients aged 65 years old and over. Cox regressions were carried out, adjusting for age, gender, psychiatric diagnosis, ethnicity, marital status, and area-level socioeconomic index. A total of 6,704 subjects were involved, including 3,368 of them having a dementia diagnosis and 3,336 of them with depression or other diagnoses. Descriptive outcomes by Kaplan-Meier curves showed significant differences between those with normal and impaired cognitive function (MMSE scoremental health services regardless of a dementia diagnosis. Causal pathways between this exposure and outcome (for example, suboptimal healthcare) need further investigation.

  3. Validity of the mini-mental state examination and the montreal cognitive assessment in the prediction of driving test outcome.

    Science.gov (United States)

    Hollis, Ann M; Duncanson, Haley; Kapust, Lissa R; Xi, Patricia M; O'Connor, Margaret G

    2015-05-01

    To evaluate the effectiveness of two cognitive screening measures, the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA), in predicting driving test outcome for individuals with and without cognitive impairment. Retrospective cohort study. A clinical driving evaluation program at a teaching hospital in the United States. Adult drivers who underwent assessment with the MMSE and MoCA as part of a comprehensive driving evaluation between 2010 and 2014 (N=92). MMSE and MoCA total scores were independent variables. The outcome measure was performance on a standardized road test. A preestablished diagnosis of cognitive impairment enhanced the validity of cognitive screening measures in the identification of at-risk drivers. In individuals with cognitive impairment there was a significant relationship between MoCA score and on-road outcome. Specifically, an individual was 1.36 times as likely to fail the road test with each 1-point decrease in MoCA score. No such relationship was detected in those without a diagnosis of cognitive impairment. For individuals who have not been diagnosed with cognitive impairment, neither the MMSE nor the MoCA can be reliably used as an indicator of driving risk, but for individuals with a preestablished diagnosis of cognitive impairment, the MoCA is a useful tool in this regard. A score on the MoCA of 18 or less should raise concerns about driving safety. © 2015, Copyright the Authors Journal compilation © 2015, The American Geriatrics Society.

  4. A system and a method for detecting the position of an object

    International Nuclear Information System (INIS)

    Brown, M.H.; Harrison, J.G.

    1982-01-01

    The position of an object e.g. a manipulator, in an enclosure is detected by two video cameras from which signals representative of images in the cameras are supplied to a mini-computer. The mini-computer scans the signals to detect the position of the object in the signals, and relates this position to the spatial coordinates of the object in the enclosure. Means are provided for controlling the movement of the object within the enclosure, which may be a hostile environment e.g. radio-active. (author)

  5. Technology of forming a positive attitude to physical training students of special medical group

    Directory of Open Access Journals (Sweden)

    Mukhamediarov N.N.

    2013-04-01

    Full Text Available Defined effective technology stages of forming a positive attitude towards physical education of students in special medical groups, stimulate motivation, epistemologically, informative, content-procedural, analytical and adjustment. For each stage technology offered special tools: lectures, seminars, analysis articles, mini conference on improving technique, racing games, mini-competitions, diagnostic interviews, questionnaires, analysis of log data on attendance. Selected criteria forming positive attitudes towards physical education: theoretical and practical, formed groups for research: experimental and control, analyzed results introduction of technology, efficiency of the proposed technology and means forming a positive attitude towards physical education students in special medical groups.

  6. Reasons for mini-implants failure: choosing installation site should be valued!

    Directory of Open Access Journals (Sweden)

    Alberto Consolaro

    2014-04-01

    Full Text Available Mini-implant loss is often associated with physical and mechanical aspects that result from choosing an inappropriate placement site. It is worth highlighting that: a Interdental alveolar bone crests are flexible and deformable. For this reason, they may not offer the ideal absolute anchorage. The more cervical the structures, the more delicate they are, thus offering less physical support for mini-implant placement; b Alveolar bone crests of triangular shape are more deformable, whereas those of rectangular shape are more flexible; c The bases of the alveolar processes of the maxilla and the mandible are not flexible, for this reason, they are more likely to receive mini-implants; d The more cervical a mini-implant is placed, the higher the risk of loss; the more apical a mini-implant is placed, the better its prognosis will be; e 3D evaluations play a major role in planning the use of mini-implants. Based on the aforementioned considerations, the hypotheses about mini-implant loss are as follows: 1 Deflection of maxillary and mandibular alveolar processes when mini-implants are more cervically placed; 2 Mini-implants placed too near the periodontal ligament, with normal intra-alveolar tooth movement; 3 Low bone density, low thickness and low alveolar bone volume; 4 Low alveolar cortical bone thickness; 5 Excessive pressure inducing trabecular bone microfracture; 6 Sites of higher anatomical weakness in the mandible and the maxilla; 7 Thicker gingival tissue not considered when choosing the mini-implant.

  7. Early diagnosis of leptospirosis

    Directory of Open Access Journals (Sweden)

    Andrea Babic-Erceg

    2014-06-01

    Full Text Available A 25-years old man from Zagreb, Croatia, was admitted to the University Hospital for Infectious Diseases four days after the onset of symptoms such as fever, intense pain in the calves and anuria. The patient owned a rabbit and, before the onset of the disease, repaired some rubber pipes damaged by rodents. At admission, he had a severe clinical picture with fever, hypotension, jaundice, immobility, and pain in leg muscles. Treatment with ceftriaxone was initiated in combination with volume restitution. Renal failure soon ensued. Consequently continuous venovenous hemodiaphiltration therapy was performed. Due to acute respiratory distress syndrome, the patient was mechanically ventilated. The patient’s condition gradually improved and he recovered fully from multi-organ failure. Diagnosis was confirmed by a microscopic agglutination test (MAT covering 15 leptospira serovars and real-time polymerase-chain reaction (PCR. The first serum sample taken on day 6 tested negative for leptospira, while PCR showed positive results for leptospiral DNA. The second serum sample taken on day 13 tested positive for serovar Canicola serogroup Canicola, serovar Patoc, serovar Grippotyphosa serogroup Grippotyphosa and serovar Tarassovi serogroup Tarassovi (titre 4000, 4000, 1000 and 2000, respectively, while PCR was negative. This report highlights the benefits of combining MAT and PCR methods in early diagnosis of leptospirosis.

  8. Radionuclide diagnosis of Meckel's diverticulum

    International Nuclear Information System (INIS)

    Conway, J.J.; Northwestern Univ., Chicago, IL

    1980-01-01

    Meckel's diverticulum can be detected with a high degree of accuracy by radionuclide scintigraphy using technetium-99m pertechnetate. The technique is without risk and should precede roentgenographic studies when the diagnosis is suspected. The method is described and the causes for false positive and false negative examinations are discussed. False negatives are rare and false positives are usually secondary to other surgical entities. Overall accuracy is 85 to 90%. (orig.) [de

  9. Mini Tuber Production in Potato Via Aeroponic System

    Directory of Open Access Journals (Sweden)

    Hussein Abdullah Ahmed AHMED

    2018-02-01

    Full Text Available The aeroponic production system is one of the new applications in soilless agriculture. This system is also an alternative seed production system for mini-tuber production of potato in terms of providing optimum growth conditions, enabling potato production to be free from diseases and pests and to make economic use of agricultural inputs. This system, which is independent of climatic conditions, has the advantage of improving the vegetative growth, delaying tuber formation, prolonging the vegetative period, increasing the tuber yield per plant and total tuber yield while decreasing the tuber weight. Due to the problems experienced in potato seedling tuber production in recent years, it emerged as an alternative production system for our country.

  10. Alcohol consumption and prostate cancer: a mini review.

    Science.gov (United States)

    Rizos, Ch; Papassava, M; Golias, Ch; Charalabopoulos, K

    2010-07-01

    Prostate cancer has become a major public health problem worldwide although the etiology of prostate cancer remains largely unknown. Dietary factors, dietary supplements, and physical activity might be important in the prevention of the disease. In the majority of studies published, it was observed that high consumption of meat, alcohol and dairy products has been linked to a greater risk. Specifically, alcohol use, and particularly heavy use, may cause cancers of liver, esophagus, larynx, pharynx and oral cavity, with risks for the aero-digestive cancers. Moderate use among women has been related with increases in breast cancer. Alcohol consumption is a modifiable lifestyle factor that may affect prostate cancer risk. Alcohol alters the hormonal environment and in parallel, containing chemical substances such as flavonoids (red wine), may alter tumor cell growth. In this mini review, the relation between alcohol consumption and prostate cancer risk is analyzed.

  11. The Dynamic Characteristic Analysis of Mini Gamma Calorimeter

    International Nuclear Information System (INIS)

    Setiyanto

    2004-01-01

    The gamma calorimeter is a facility to measure the gamma heating in the nuclear reactor. The dimensions of the conventional calorimeters are in general too large, that is an inconvenience if those calorimeters will be applied in the high temperature reactor as a nuclear power plant. To avoid that inconvenience, it is necessary to propose the innovation on the feature of the existing calorimeter. The basic idea of the innovation is to create the small type of calorimeter without the absorbed material. The last analysis was realized to determine of the static calorimeter characteristic or sensitivities as a function of the dimension and the material of gas isolations. Based on those results, the analyses is reasonably to be continued to determine the dynamic characteristic or period of calorimeter. The analysis was performed using the finite difference method, two dimension simplified. It can be concluded that the mini gamma calorimeter proposed is reasonable to be made. (author)

  12. Real time simulation of large systems on mini-computer

    International Nuclear Information System (INIS)

    Nakhle, Michel; Roux, Pierre.

    1979-01-01

    Most simulation languages will only accept an explicit formulation of differential equations, and logical variables hold no special status therein. The pace of the suggested methods of integration is limited by the smallest time constant of the model submitted. The NEPTUNIX 2 simulation software has a language that will take implicit equations and an integration method of which the variable pace is not limited by the time constants of the model. This, together with high time and memory ressources optimization of the code generated, makes NEPTUNIX 2 a basic tool for simulation on mini-computers. Since the logical variables are specific entities under centralized control, correct processing of discontinuities and synchronization with a real process are feasible. The NEPTUNIX 2 is the industrial version of NEPTUNIX 1 [fr

  13. Four Channel Mini Wire Chamber to Study Cosmic Rays

    Science.gov (United States)

    Felix, J.; Rodriguez, G. J.

    2018-01-01

    Multiwire proportional chamber is a conventional technique to study radiation in general, and cosmic rays in particular. To study cosmic rays, it was planned, designed, constructed, characterized, and tested a four channel mini wire chamber, based on two 3 cm × 3 cm × 0.6 cm Aluminum frames, two 3 cm × 3 cm × 0.6 cm plastic frames, two 3 cm × 3 cm × 0.3 cm Aluminum frames, two electronic planes each with two Tungsten Gold plated 1 mil diameter wires, parallel and 1 cm apart each other at 25 g stretched-each plane was 90° rotated each other in the final assemble- and two Aluminum foil window to define the gas volume; it was operated with Argon 90%-CH4 10% gas mixture at 1 atmosphere and ambient temperature (20°C in the average). It is presented technical details, results on characterization, and preliminary results on cosmic rays detection.

  14. Report of the transition crossing mini-workshop

    International Nuclear Information System (INIS)

    Martin, P.; Chou, W.

    1996-07-01

    This was the first in a series of mini-workshops on high intensity, high brightness hadron beams. Twenty five people from CERN, KEK, BNL, Fermilab and University of Houston attended the workshop. The first day was a plenary session with nine presentations. On the second day, three working groups (WG) were formed: WG-I was on theory, simulation and measurements, led by J.P. Riunaud (CERN) and P.L. Colestock (Fermilab); WG-II was on γ t -jump systems, led by T. Roser (BNL) and W. Chou (Fermilab); WG-III was on new schemes, led by Y. Mori (KEK) and J. Griffin (Fermilab). Each group gave a presentation at the final plenary session. The summaries from the three working groups are included in this report. During the workshop, P. Martin gave a guided tour to the Main Injector tunnel, which is under construction at Fermilab

  15. Heterotic Mini-landscape in blow-up

    CERN Document Server

    Bizet, Nana Geraldine Cabo

    2013-01-01

    Localization properties of fields in compact extra dimensions are crucial ingredients for string model building, particularly in the framework of orbifold compactifications. Realistic models often require a slight deviation from the orbifold point, that can be analyzed using field theoretic methods considering (singlet) fields with nontrivial vacuum expectation values. Some of these fields correspond to blow-up modes that represent the resolution of orbifold singularities. Improving on previous analyses we give here an explicit example of the blow-up of a model from the heterotic Mini-landscape. An exact identification of the blow-up modes at various fixed points and fixed tori with orbifold twisted fields is given. We match the massless spectra and identify the blow-up modes as non-universal axions of compactified string theory. We stress the important role of the Green-Schwarz anomaly polynomial for the description of the resolution of orbifold singularities.

  16. PV-HYBRID and MINI-GRID. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    Within the 3rd European Conference at the Centre de Congres in Aix en Provence (France) between 11th and 12th May, 2006, the following lessons were held: (1) Small electric networks: European drivers and projects for the integration of RES and DG into the electricity grids of the future (Manuel Sanchez-Jimenez); (2) PV hybrid system within mini grids - IEA PVPS programme (Meuch Konraf); (3) Renewables for the developing world (Alvaro Ponce Plaza); (4) Rural electicity supply using photovoltaic / - Diesel hybrid systems: Attractive for investors in the renewable energy sector? (Andreas Hahn); (5) Economic analysis of stand-alone and grid-connected photovoltaic systems under current tariff structure of Taiwan (Yaw-Juen Wang); (6) Using wind-PV-diesel hybrid system for electrification of remote village in Western Libya (N.M. Kreama); (7) Venezuela's renewable energy program for small towns and rural areas ''Sembrando Luz'' (Jorge Torres); (8) AeroSmart5, the professional, sysem-compatible small-scale wind energy converter will be tested in field tests (Fabian Jochem); (9) Lifetime, test procedures and recommendations for optimal operating strategies for lead-acid-batteries in renewable energy systems - A survey on results from European projects from the 5th framework programme (Rudi Kaiser); (10) Prototype of a reversible fuel cell system for autonomous power supplies (Tom Smolinska); (11) Interconnection management in microgrids (Michel Vandenbergh); (12) Control strategy for a small-scale stand-alone power system based on renewable energy and hydrogen (Harald Miland); (13) Standard renewable electricity supply for people in rural areas - mini-grids in western provinces of China (Michael Wollny); (14) The Brava island a ''100% renewable energy'' project (Jean-Christian Marcel); (15) Breakthrough to a new era of PV-hybrid systems with the help of standardised components communication? (Michael Mueller); (16) Standardized

  17. Investigation of a robust tendon-sheath mechanism for flexible membrane wing application in mini-UAV

    Science.gov (United States)

    Lee, Shian; Tjahjowidodo, Tegoeh; Lee, Hsuchew; Lai, Benedict

    2017-02-01

    Two inherent issues manifest themselves in flying mini-unmanned aerial vehicles (mini-UAV) in the dense area at tropical climate regions, namely disturbances from gusty winds and limited space for deployment tasks. Flexible membrane wing (FMW) UAVs are seen to be potentials to mitigate these problems. FMWs are adaptable to gusty airflow as the wings are able to flex according to the gust load to reduce the effective angle-of-attack, thus, reducing the aerodynamic loads on the wing. On the other hand, the flexible structure is allowing the UAV to fold in a compact package, and later on, the mini-UAV can be deployed instantly from the storage tube, e.g. through a catapult mechanism. This paper discusses the development of an FMW UAV actuated by a tendon-sheath mechanism (TSM). This approach allows the wing to morph to generate a rolling moment, while still allowing the wing to fold. Dynamic characteristics of the mechanism that exhibits the strong nonlinear phenomenon of friction on TSM are modeled and compensated for. A feed-forward controller was implemented based on the identified nonlinear behavior to control the warping position of the wing. The proposed strategy is validated experimentally in a wind tunnel facility by creating a gusty environment that is imitating a realistic gusty condition based upon the results of computational fluid dynamics (CFD) simulation. The results demonstrate a stable and robust wing-warping actuation, even in gusty conditions. Accurate wing-warping can be achieved via the TSM, while also allowing the wings to fold.

  18. [Molecular tests in diagnosis of Cytomegalovirus (CMV), human herpesvirus 6 (HHV-6) and Epstein-Barr virus (EBV) using real-time PCR in HIV positive and HIV-negative pregnant women in Ouagadougou, Burkina Faso].

    Science.gov (United States)

    Ouedraogo, Alice Rogomenoma; Kabre, Madeleine; Bisseye, Cyrille; Zohoncon, Théodora Mahoukèdè; Asshi, Maleki; Soubeiga, Serge Théophile; Diarra, Birama; Traore, Lassina; Djigma, Florencia Wendkuuni; Ouermi, Djénéba; Pietra, Virginio; Barro, Nicolas; Simpore, Jacques

    2016-01-01

    Herpesvirus EBV, CMV and HHV-6 are viruses that evolve based on pandemic modeling and are responsible for congenital infections causing severe sequelae in infants. This study aims to determine the prevalence of CMV, EBV and HHV-6 among HIV (+) and HIV (-) pregnant women in Ouagadougou. In this study 200 blood plasma samples taken from pregnant women, of whom 100 with HIV(+) and 100 with HIV(-), were analyzed using multiplex real-time PCR which detected three infections (EBV, CMV and HHV-6). Out of the 200 samples tested, 18(9.0%) were positive for at least one of the three viruses, 12(6.0%) were positive for EBV, 13(6.5%) were positive for CMV and 12(6.0%) were positive for HHV-6. Among the 18 cases with infections, 10 cases (55.6%) had co-infections of whom 90.0% (9/10) with multiple EBV/CMV/HHV6 infection and 10.0% with EBV/HHV6 co-infection. HHVs infection rate was higher among HIV (-) pregnant women than among HIV (+) pregnant women (12.0% versus 6.0%). Among HIV (+) pregnant women, PCR showed 7.1% (6/85) of HHVs infection in patients who were not treated with ARV against 0% in those treated with ARVs. Herpes virus infections are a common condition in pregnant women in Burkina Faso. They may represent a real threat to pregnant women because of complications and risks of infection in infants.

  19. Where are the mini Kreutz-family comets?

    International Nuclear Information System (INIS)

    Ye, Quan-Zhi; Wiegert, Paul A.; Hui, Man-To; Kracht, Rainer

    2014-01-01

    The Kreutz family of sungrazing comets contains over 2000 known members, many of which are believed to be under ∼100 m sizes (mini comets) and have only been studied at small heliocentric distances (r H ) with space-based SOHO/STEREO spacecraft. To understand the brightening process of mini Kreutz comets, we conducted a survey using CFHT/MegaCam at moderate r H guided by SOHO/STEREO observations. We identify two comets that should be in our search area but are not detected, indicating that the comets have either followed a steeper brightening rate within the previously reported rapid brightening stage (the brightening burst), or the brightening burst starts earlier than expected. We present a composite analysis of the pre-perihelion light curves of five Kreutz comets that cover to ∼1 AU. We observe significant diversity in the light curves that can be used to grossly classify them into two types: C/Ikeya-Seki and C/SWAN follow the canonical r H −4 while the others follow r H −7 . In particular, C/SWAN seems to have undergone an outburst (Δm > 5 mag) or a rapid brightening (n ≳ 11) between r H = 1.06 AU and 0.52 AU, and shows hints of structural/compositional differences compared to other bright Kreutz comets. We also find evidence that the Kreutz comets as a population lose their mass less efficiently than the dynamically new comet, C/ISON, and are relatively devoid of species that drive C/ISON's activity at large r H . Concurrent observations of C/STEREO in different wavelengths also suggest that a blueward species such as CN may be the main driver for brightening bursts, instead of sodium as previously thought

  20. Superparticle phenomenology from the natural mini-landscape

    Science.gov (United States)

    Baer, Howard; Barger, Vernon; Savoy, Michael; Serce, Hasan; Tata, Xerxes

    2017-06-01

    The methodology of the heterotic mini-landscape attempts to zero in on phenomenologically viable corners of the string landscape where the effective low energy theory is the Minimal Supersymmetric Standard Model with localized grand unification. The gaugino mass pattern is that of mirage-mediation. The magnitudes of various SM Yukawa couplings point to a picture where scalar soft SUSY breaking terms are related to the geography of fields in the compactified dimensions. Higgs fields and third generation scalars extend to the bulk and occur in split multiplets with TeV scale soft masses. First and second generation scalars, localized at orbifold fixed points or tori with enhanced symmetry, occur in complete GUT multiplets and have much larger masses. This picture can be matched onto the parameter space of generalized mirage mediation. Naturalness considerations, the requirement of the observed electroweak symmetry breaking pattern, and LHC bounds on m g together limit the gravitino mass to the m 3/2 ˜ 5-60 TeV range. The mirage unification scale is bounded from below with the limit depending on the ratio of squark to gravitino masses. We show that while natural SUSY in this realization may escape detection even at the high luminosity LHC, the high energy LHC with √{s}=33 TeV could unequivocally confirm or exclude this scenario. It should be possible to detect the expected light higgsinos at the ILC if these are kinematically accessible, and possibly also discriminate the expected compression of gaugino masses in the natural mini-landscape picture from the mass pattern expected in models with gaugino mass unification. The thermal WIMP signal should be accessible via direct detection searches at the multi-ton noble liquid detectors such as XENONnT or LZ.

  1. Hydrological assessment for mini hydropower potential at Sungai Pahang - Temerloh

    International Nuclear Information System (INIS)

    Sidek, L M; Zaki, A Z A; Muda, Z C; Basri, H; Mustaffa, Z; Ibrahim, M I H; Thiruchelvam, S

    2013-01-01

    Sg Pahang at Temerloh was considered for assessment of hydropower potential using hydrological analysis method and hydrological model. The available data related to topography, soil, land use, weather and discharge pertaining to the study catchment were used to characterize the catchment. The characterization was required for water resources hence hydropower assessment. The hydrology of the study catchment was simulated through the model. This hydrological study is required due to the proposed mini hydroelectric power plant at Pulau Temerloh. It is essential to evaluate the existing river flow characteristic and to model the environmental flow assessment of the river. Two rainfalll stations, JPS Temerloh and Pintu Kawalan Paya Kertam Station are selected to develop the Rainfall Intensity Duration frequency (RIDF) Curve to determine the rainfall intensity of the area. Daily river flow were recorded at Sg Pahang at Temerloh and Sg Pahang at Lubok Paku were used to develop the Flow Duration Curve (FDC) to study the characteristic of Sungai Pahang flow. The 7 days low flow with 10 years return period (7Q10 low flow) was obtained using both Gumbel Method and Log Pearson Type III Method. The results from FDC shows that 50% percentage of time the Sg Pahang - Temerloh is exceeded over a historical period is 400 m 3 /s and 50% percentage of time the Sg Pahang - Lubok Paku is exceeded over a historical period is 650 m 3 /s. The required environmental flow are set to be 7Q10 low flow which is 64.215 m 3 /s for Sg Pahang at Temerloh and 79.24 m 3 /s for Sg Pahang at Lubok Paku. The results show the water resources are abundant and hence boost the mini hydropower potentiality at Sg Pahang.

  2. Dancing as an Intervention Tool for People with Dementia: A Mini-Review Dancing and Dementia.

    Science.gov (United States)

    Klimova, Blanka; Valis, Martin; Kuca, Kamil

    2017-01-01

    Research studies show a positive impact of physical activities such as dancing on the improvement of cognitive reserves of people with dementia. The purpose of this study is to explore dancing efficacy on people with dementia and list the key benefits and limitations of dancing therapy for these people. The methods used in this study include a method of literature review of available Englishwritten sources with respect to the dancing therapy and dementia in the acknowledged databases Pub- Med, Web of Science, Springer, and Scopus, and a method of comparison and evaluation of their findings. The findings of this mini review confirm positive efficacy of dancing therapy on cognitive, physical, emotional and social performance of people with dementia. More randomized controlled clinical trials should be conducted in this field, as well as other non-pharmacological therapies should be employed in order to holistically contribute to the prevention and treatment of dementia. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  3. Reconciling results of LSND, MiniBooNE and other experiments with soft decoherence

    CERN Document Server

    Farzan, Yasaman; Smirnov, Alexei Yu

    2008-01-01

    We propose an explanation of the LSND signal via quantum-decoherence of the mass states, which leads to damping of the interference terms in the oscillation probabilities. The decoherence parameters as well as their energy dependence are chosen in such a way that the damping affects only oscillations with the large (atmospheric) $\\Delta m^2$ and rapidly decreases with the neutrino energy. This allows us to reconcile the positive LSND signal with MiniBooNE and other null-result experiments. The standard explanations of solar, atmospheric, KamLAND and MINOS data are not affected. No new particles, and in particular, no sterile neutrinos are needed. The LSND signal is controlled by the 1-3 mixing angle $\\theta_{13}$ and, depending on the degree of damping, yields $0.0014 < \\sin^2\\theta_{13} < 0.034$ at $3\\sigma$. The scenario can be tested at upcoming $\\theta_{13}$ searches: while the comparison of near and far detector measurements at reactors should lead to a null-result a positive signal for $\\theta_{13...

  4. [Our experience with mini tapes (TVT Secur and MiniArc) in the surgery for stress urinary incontinence].

    Science.gov (United States)

    Jiménez Calvo, J; Hualde Alfaro, A; Raigoso Ortega, O; Cebrian Lostal, J L; Alvarez Bandres, S; Jiménez Parra, J; Montesino Semper, M; Santiago Gonzalez de Garibay, A

    2008-01-01

    The purpose of this publication is to describe the surgical technique, assess complications and short-term results of TVT secur and MiniArc tapes. From October 2006 to August 2007 it was carried out the surgical correction with TVT Secur,Women's Health & Urology, Ethicon, Johnson & Johnson, placing the tape as a hammock, to 51 patients, 38 of them with pure stress incontinence and 13 with mixed incontinence and with an average age of 57 years. From September 2007 to February 2008 41 patients, 33 of them with pure stress incontinence and 8 with mixed incontinence, with an average of age of 58 years were operated with AMS Miniarc swing system tape, posted on hammock. All procedures were performed with sedoanalgesia and Ambulatory Surgery regime. Patients were monitored in outpatient visits one month, 3 months and one year after surgical procedure. Medical history and questionnaire and ICIQ-SF, to which we added a question to quantify the degree of satisfaction, as well as physical examination, were done. We compared the results of both technical procedures and statistical survey was conducted by Student test. [Analysis with SPSS software (V14.0)]. The median follow-up in TVT secur group was 328 days (range 163-522 days) and 101 days (range 41-209 days) inthe MiniArc group. We only had one (TVT secur group) surgical complication in all the series (92 patients) being a bladder perforation. Taking into account that we read a negative test effort as an objective cure in the TVT secur group, 80.4% patients are cured and 90.2% inthe MiniArc group without significant difference between both groups (p 0095). To assess the subjective healing we utilized the ICIQ-SF test and the satisfaction extra-question and we noted that there is no significant difference between the first and third month controls. (90% of patients satisfied). 80% of patients were completely satisfied in the first year control that was only performed to TVT secur group. These new tapes show fewer

  5. Negative Suction Drain Through a Mini Periareolar Incision for the Treatment of Lactational Breast Abscess Shortens Hospital Stay and Increases Breastfeeding Rates.

    Science.gov (United States)

    Wei, Jinli; Zhang, Jiaxin; Fu, Deyuan

    2016-06-01

    Although breast abscess is a serious uncommon complication of mastitis with high morbidity rate, there is a lack of high-quality randomized trial to demonstrate the best treatments. We reported a novel way of applying negative suction drain through a mini periareolar incision. We retrospectively analyzed and compared the clinical characteristics of 62 patients with lactational breast abscess in our department from August 2012 to April 2015. Thirty-two patients went through traditional incision and drainage (Group A) and 30 patients were placed on negative suction drain through mini periareolar incision (Group B). There is no significant difference between the two groups in terms of age, white blood cell (WBC) count, size of the abscess cavity, and positive rate of Staphylococcus aureus (SA) or methicillin-resistant Staphylococcus aureus (MRSA). Patients in Group B had a shorter hospitalized stay (p = 0.003) and had a higher rate of continuation of breastfeeding (p breast abscess and maintaining breastfeeding.

  6. First case report of staghorn calculi successfully removed by mini-endoscopic combined intrarenal surgery in a 2-year-old boy.

    Science.gov (United States)

    Taguchi, Kazumi; Hamamoto, Shuzo; Okada, Atsushi; Mizuno, Kentaro; Tozawa, Keiichi; Hayashi, Yutaro; Kohri, Kenjiro; Yasui, Takahiro

    2015-10-01

    Less-invasive therapy for pediatric urolithiasis is available due to the miniaturization of equipment and improved optics; however, surgical treatment strategies, especially for large calculi, remain controversial. We describe here our experience of treating a 2-year-old boy with left renal staghorn calculi with a single session of mini-endoscopic combined intrarenal surgery in the prone split-leg position with pre-ureteral stenting and the directional enhanced flow imaging ultrasound technique. This is the first report of successful pediatric mini-endoscopic combined intrarenal surgery without any major complications. We believe this technique provides an important therapeutic option for large renal calculus in pediatric patients. © 2015 The Japanese Urological Association.

  7. Correlation between the Mini Mental State Examination-Korean version and the Measurement of Quality of the Environment in the institutionalized elderly.

    Science.gov (United States)

    Kim, Myoung-Kwon; Kim, Tae Hoon; Kim, Seong-Gil

    2015-11-01

    [Purpose] This study aimed to investigate the correlation between the cognitive level of the elderly and their attitude towards the living environment. [Subjects and Methods] A total of 80 elderly people hospitalized in a nursing home in K city, South Korea, participated in this study. Pearson correlation analysis was used to test the relationships between scores on the Mini Mental State Examination-Korean Version and Measurement of Quality of the Environment (facilitators and obstacles). [Results] A positive and moderately strong correlation (r = 0.462) was found between scores on the Mini Mental State Examination and the Measurement of Quality of the Environment (obstacle). [Conclusion] In a nursing home, patients with relatively higher cognitive levels can perceive more obstacles in the surrounding environment.

  8. The Mini-Cog versus the Mini-Mental State Examination and the Clock Drawing Test in daily clinical practice: screening value in a German Memory Clinic.

    Science.gov (United States)

    Milian, Monika; Leiherr, Anna-Maria; Straten, Guido; Müller, Stephan; Leyhe, Thomas; Eschweiler, Gerhard W

    2012-05-01

    The aim of this study was to compare the screening value of the Mini-Cog, Clock Drawing Test (CDT), Mini-Mental State Examination (MMSE) and the algorithm MMSE and/or CDT to separate elderly people with dementia from healthy depending on test time, type and severity of dementia, and demographic variables in a German Memory Clinic. Data from a heterogeneous patient sample and healthy participants (n = 502) were retrospectively analyzed. Of the 438 patients with dementia, 49.1% of the dementia diagnoses were Alzheimer's dementia and 50.9% were non-Alzheimer's dementia. Sixty-four participants were classified as cognitively unimpaired. The CDT and an extraction of the 3-item recall of the MMSE were used to constitute the Mini-Cog algorithm. Overall, the Mini-Cog showed significantly higher discriminatory power (86.8%) than the MMSE (72.6% at a cut-off ≤ 24 and 79.2% at ≤ 25, respectively) and CDT (78.1%) (each p 0.05). The specificity of the Mini-Cog (100.0%) was similar to that of the MMSE (100.0% for both cut-offs) and CDT (96.9%) (p = 0.154). For all age and educational groups the Mini-Cog outmatched the CDT and MMSE, and was less affected by education than MMSE and less susceptible for the dementia stage than the CDT. The Mini-Cog proved to have superior discriminatory power than either CDT or MMSE and is demonstrated to be a valid "short" screening instrument taking 3 to 4 minutes to administer in the geriatric setting.

  9. Protective factor screening for prevention practice: Sensitivity and specificity of the DESSA-Mini.

    Science.gov (United States)

    Shapiro, Valerie B; Kim, B K Elizabeth; Robitaille, Jennifer L; LeBuffe, Paul A

    2017-12-01

    The Devereux Student Strengths Assessment Mini (DESSA-Mini; Naglieri, LeBuffe, & Shapiro, 2011/2014) was designed to overcome practical obstacles to universal prevention screening. This article seeks to determine whether an entirely strength-based, 8-item screening instrument achieves technical accuracy in routine practice. Data come from a district-wide implementation of a new social emotional learning (SEL) initiative designed to promote students' social-emotional competence. All students, kindergarten through Grade 8, were screened using the DESSA-Mini. A random 5 students per classroom received additional assessment. Concurrent and predictive criterion studies were conducted using the full DESSA as well as administrative records of serious disciplinary infraction. The DESSA-Mini showed excellent internal reliability, exceeding .90. Negligible to small differences were found between scores on the DESSA-Mini screen and the DESSA full assessment. Classification consistency between the DESSA-Mini and the DESSA was high (87%-94%) in routine practice, with sensitivity and specificity estimates exceeding Glascoe's (2005) standards. Finally, predictive validity of the DESSA-Mini was reliable; students screened as having a Need for SEL Instruction at the beginning of the year were 4.5 times more likely to have a record of serious disciplinary infraction at the end of the school year compared with those who were not identified (p mental, emotional, and behavioral problems. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  10. Impact of implant design on primary stability of orthodontic mini-implants.

    Science.gov (United States)

    Wilmes, Benedict; Ottenstreuer, Stephanie; Su, Yu-Yu; Drescher, Dieter

    2008-01-01

    Skeletal anchorage with mini-implants has greatly broadened the treatment possibilities in orthodontics over the last few years. To reduce implant failure rates, it is advisable to obtain adequate primary stability. The aim of this study was to quantitatively analyze the impact of implant design and dimension on primary stability. Forty-two porcine iliac bone segments were prepared and embedded in resin. To evaluate the primary stability, we documented insertion torques of the following mini-implants: Aarhus Screw, AbsoAnchor, LOMAS, Micro-Anchorage-System, ORLUS and Spider Screw. In each bone, five Dual Top Screws were inserted for reference purposes to achieve comparability among the specimens. We observed wide variation in insertion torques and hence primary stability, depending on mini-implant design and dimension; the great impact that mini-implant diameter has on insertion torques was particularly conspicuous. Conical mini-implants achieved higher primary stabilities than cylindrical designs. The diameter and design of the mini-implant thread have a distinctive impact on primary stability. Depending on the region of insertion and local bone quality, the choice of the mini-implant design and size is crucial to establish sufficient primary stability.

  11. Purification and characterization of mutant miniPlasmin for thrombolytic therapy

    Directory of Open Access Journals (Sweden)

    Lin Xiaotao

    2013-01-01

    Full Text Available Abstract Background Previous animal studies by us and others have indicated that catheter-administered plasmin or its des-kringle derivatives may be more appropriate alternatives to plasminogen activators for treating thrombolytic diseases, since it has a very short serum half-life and therefore does not result in hemorrhaging. We have previously produced recombinant miniPlasmin (mPlasmin that was proven suitable for treating peripheral arterial occlusion in animal models. However, our previous results showed that non-specific cleavage at position K698 of mPlasmin during activation hindered the further development of this promising therapeutic candidate. In order to minimize or eliminate the non-specific cleavage problem, we performed saturation mutagenesis at the K698 position to develop a mutant form of mPlasmin for thrombolytic therapy. Methods We changed K698 to 16 other amino acids, with preferred E. coli codons. Each of these mutants were expressed in E. coli as inclusion bodies and then refolded, purified, and subsequently characterized by detailed kinetic assays/experiments/studies which identified highly active mutants devoid of non-specific cleavage. Results Activation studies indicated that at those conditions in which the wild type enzyme is cut at the non-specific position K698, the active mutants can be activated without being cleaved at this position. Conclusions From the above results, we selected two mutants, K698Q and K698N, as our lead candidates for further thrombolytic drug developments. The selected mutants are potentially better therapeutic candidates for thrombolytic therapy.

  12. Researcher positioning

    DEFF Research Database (Denmark)

    Mørck, Line Lerche; Khawaja, Iram

    2009-01-01

    abstract  This article focuses on the complex and multi-layered process of researcher positioning, specifically in relation to the politically sensitive study of marginalised and ‘othered' groups such as Muslims living in Denmark. We discuss the impact of different ethnic, religious and racial...... political and personal involvement by the researcher, which challenges traditional perspectives on research and researcher positioning. A key point in this regard is the importance of constant awareness of and reflection on the multiple ways in which one's positioning as a researcher influences the research...

  13. The Lagrangian structure of ozone mini-holes and potential vorticity anomalies in the Northern Hemisphere

    Directory of Open Access Journals (Sweden)

    P. M. James

    2002-06-01

    Full Text Available An ozone mini-hole is a synoptic-scale area of strongly reduced column total ozone, which undergoes a growth-decay cycle in association with baroclinic weather systems. The tracks of mini-hole events recorded during the TOMS observation period over the Northern Hemisphere provide a database for building anomaly fields of various meteorological parameters, following each mini-hole center in a Lagrangian sense. The resulting fields provide, for the first time, a complete mean Lagrangian picture of the three-dimensional structure of typical ozone mini-holes in the Northern Hemisphere. Mini-holes are shown to be associated with anomalous warm anticyclonic flow in the upper troposphere and cold cyclonic anomalies in the middle stratosphere. Ascending air columns occur upstream and descent downstream of the mini-hole centers. Band-pass filtering is used to reveal the transient synoptic nature of mini-holes embedded within larger scale circulation anomalies. Significant correlations between ozone and Ertel’s potential vorticity on isentropes (IPV both near the tropopause and in the middle stratosphere are shown and then utilized by reconstructing the Lagrangian analysis to follow local IPV anomalies instead of ozone minima. By using IPV as a proxy for ozone, the geopotential anomaly dipolar structure in the vertical characteristic of mini-holes is shown to result from a superposition of two largely independent dynamical components, stratospheric and tropospheric, typically operating on different time scales. Hence, ozone mini-holes may be viewed primarily as phenomena of coincidence.Key words. Meteorology and atmospheric dynamics (middle atmosphere dynamics; synoptic-scale meteorology

  14. The Lagrangian structure of ozone mini-holes and potential vorticity anomalies in the Northern Hemisphere

    Directory of Open Access Journals (Sweden)

    P. M. James

    Full Text Available An ozone mini-hole is a synoptic-scale area of strongly reduced column total ozone, which undergoes a growth-decay cycle in association with baroclinic weather systems. The tracks of mini-hole events recorded during the TOMS observation period over the Northern Hemisphere provide a database for building anomaly fields of various meteorological parameters, following each mini-hole center in a Lagrangian sense. The resulting fields provide, for the first time, a complete mean Lagrangian picture of the three-dimensional structure of typical ozone mini-holes in the Northern Hemisphere. Mini-holes are shown to be associated with anomalous warm anticyclonic flow in the upper troposphere and cold cyclonic anomalies in the middle stratosphere. Ascending air columns occur upstream and descent downstream of the mini-hole centers. Band-pass filtering is used to reveal the transient synoptic nature of mini-holes embedded within larger scale circulation anomalies. Significant correlations between ozone and Ertel’s potential vorticity on isentropes (IPV both near the tropopause and in the middle stratosphere are shown and then utilized by reconstructing the Lagrangian analysis to follow local IPV anomalies instead of ozone minima. By using IPV as a proxy for ozone, the geopotential anomaly dipolar structure in the vertical characteristic of mini-holes is shown to result from a superposition of two largely independent dynamical components, stratospheric and tropospheric, typically operating on different time scales. Hence, ozone mini-holes may be viewed primarily as phenomena of coincidence.

    Key words. Meteorology and atmospheric dynamics (middle atmosphere dynamics; synoptic-scale meteorology

  15. Mandibular Overdentures Retained by Two Mini-Implants: A Seven-Year Retention and Satisfaction Study.

    Science.gov (United States)

    Catalán, Alfonso; Martínez, Alejandra; Marchesani, Francisco; González, Urcesino

    2016-07-01

    Patients with atrophic edentulous ridges generally have problems with retention, therapeutic satisfaction, and comfort with their complete dentures. An alternative treatment to assist in improving retention and stability involves the use of mini-implants. The aim of this study was to evaluate the retention of mandibular overdentures connected to two mini-implants and overall patient satisfaction with them. Seven patients with atrophic mandibular ridges (Type 4D Misch classification), aged 62 to 74 years old were rehabilitated with complete dentures. In each patient, two mini-implants measuring 15 or 13 mm in length and 1.8 mm in diameter were placed. After 15 days, overdentures were connected to the mini-implants with O-ring attachments. In each patient, retention of the overdentures was measured, and a survey of therapeutic satisfaction before and after connection to the mini-implants was administered. Prosthesis retention was measured with a digital dynamometer at 1 month, 6 months, and 2, 3, 5, and 7 years after mini-implant placement. Patient satisfaction was assessed with a survey. Data were analyzed with Student's t-test (satisfaction survey) and the Friedman test (retention measurements and satisfaction survey). The initial retention values (0.34 to 0.63 N without mini-implants) varied significantly (p ≤ 0.050). These values were less than the subsequent measurements of 3.92 to 9.64 N, taken after placement of the mini-implants and connecting them to the dentures. Satisfaction was good to very good over the 7-year observation period. Mucosa and peri-implant bone showed no pathological changes. In this limited sample size clinical study the results indicated that after connecting mandibular overdentures to two mini-implants, patient satisfaction significantly increased and retention significantly improved during the 7-year observation period. © 2015 by the American College of Prosthodontists.

  16. Differential diagnosis of disseminated periventricular calcifications

    International Nuclear Information System (INIS)

    Rieger, P.; Piepgras, U.

    1986-01-01

    Juvenile disseminated periventricular calcifications may occur in tuberous sclerosis, toxoplasmosis, cytomegaly, and in tuberculous meningitis. Cysticercosis, by contrast, does not result in corresponding intracerebral foci until an older age. Differential diagnosis is no problem if clinical findings are typical (tuberous sclerosis) or if serological verification is positive. However, any unclear clinical diagnosis can often be secured by CT. (orig.) [de

  17. Differential diagnosis of disseminated periventricular calcifications

    Energy Technology Data Exchange (ETDEWEB)

    Rieger, P.; Piepgras, U.

    1986-08-01

    Juvenile disseminated periventricular calcifications may occur in tuberous sclerosis, toxoplasmosis, cytomegaly, and in tuberculous meningitis. Cysticercosis, by contrast, does not result in corresponding intracerebral foci until an older age. Differential diagnosis is no problem if clinical findings are typical (tuberous sclerosis) or if serological verification is positive. However, any unclear clinical diagnosis can often be secured by CT.

  18. Entrepreneur and Establishment of a Mini Hotel in XiChang, China

    OpenAIRE

    Hu, Mingsong

    2013-01-01

    Mini Hotel, is a new hotel will be opened in China in this year. I and 4 of my friends will be the shareholders of this Mini Hotel. The hotel is planned to be operating from the autumn of 2013. Now, everything in this thesis is on process. The main objective of this thesis was to draft an effective approach to ensure this is a right plan which is worth to invest. By using benchmarking and SWOT analysis we defined the strength and weakness of this Mini Hotel business plan. This thesis will ...

  19. Investigation of Heat Transfer in Mini Channels using Planar Laser Induced Fluorescence

    DEFF Research Database (Denmark)

    Bøgild, Morten Ryge; Poulsen, Jonas Lundsted; Rath, Emil Zacho

    2012-01-01

    In this paper an experimental investigation of the heat transfer in mini channels with a hydraulic diameter of 889 m is conducted. The method used is planar laser induceduorescence (PLIF), which uses the principle of laser excitation of rhodamine B in water. The goal of this study is to validate...... the applicability of PLIF to determine the convective heat transfer coecient in mini channels against conventional correlations of the convective heat transfer coecient. The applicability of the conventional theory in micro and mini channels has been discussed by several researchers, but to the authors knowledge...

  20. Characterization of surface topography and chemical composition of mini-implants

    OpenAIRE

    Knop, Luegya Amorim Henriques; Soares, Ana Prates; Shintcovsk, Ricardo Lima; Martins, Lidia Parsekian; Gandini Jr., Luiz Gonzaga

    2015-01-01

    Abstract Aim : To assess the surface topography and chemical composition of three brands of as-received mini-implants (SIN(r), Morelli(r), and Conexao(r)). Methods: Twelve mini-implants of each brand were analyzed by scanning electron microscopy and energy dispersive X-ray (EDX). Results: There was no significant differences among SIN(r), Morelli(r), and Conexao(r) mini-implants comparing their surface topography by visualization of SEM micrographs and analysis of scores. The EDX analysis ...

  1. Radiographic positioning

    International Nuclear Information System (INIS)

    Eisenberg, R.L.; Dennis, C.A.; May, C.

    1989-01-01

    This book concentrates on the routine radiographic examinations commonly performed. It details the wide variety of examinations possible and their place in initial learning and in the radiology department as references for those occasions when an unusual examination is requested. This book provides information ranging from basic terminology to skeletal positioning to special procedures. Positions are discussed and supplemented with a picture of a patient, the resulting radiograph, and a labeled diagram. Immobilization and proper shielding of the patient are also shown

  2. Position encoder

    International Nuclear Information System (INIS)

    Goursky, Vsevolod

    1975-01-01

    A circuitry for deriving the quotient of signal delivered by position-sensitive detectors is described. Digital output is obtained in the form of 10- to 12-bit words. Impact position may be determined with 0.25% accuracy when the dynamic range of the energy signal is less 1:10, and 0.5% accuracy when the dynamic range is 1:20. The division requires an average time of 5μs for 10-bit words

  3. Position encoder

    International Nuclear Information System (INIS)

    Goursky, V.

    1975-05-01

    This paper describes circuitry for deriving the quotient of signals delivered by position-sensitive detectors. Digital output is obtained in the form of 10 to 12 bit words. Impact position may be determined with 0.25% accuracy when the dynamic range of the energy signal is less than 1:10, and 0.5% accuracy when the dynamic range is 1:20. The division requires an average time of 5μs for 10-bit words [fr

  4. Estimation of diagnostic performance of dementia screening tests: Mini-Mental State Examination, Mini-Cog, Clock Drawing test and Ascertain Dementia 8 questionnaire.

    Science.gov (United States)

    Yang, Li; Yan, Jing; Jin, Xiaoqing; Jin, Yu; Yu, Wei; Xu, Shanhu; Wu, Haibin; Xu, Ying; Liu, Caixia

    2017-05-09

    Dementia is one of the leading causes of dependence in the elderly. This study was conducted to estimate diagnostic performance of dementia screening tests including Mini-Mental State Examination (MMSE), Mini-Cog, Clock Drawing Test (CDT) and Ascertain Dementia 8 questionnaire (AD8) by Bayesian models. A total of 2015 participants aged 65 years or more in eastern China were enrolled. The four screening tests were administered and scored by specifically trained psychiatrists. The prior information of sensitivity and specificity of every screening test was updated via Bayes' theorem to a posterior distribution. Then the results were compared with the estimation based on National Institute of Aging-Alzheimer's Association criteria (NIA-AA). The diagnostic characteristics of Mini-Cog, including sensitivity, specificity, PPV, NPV, especially the Youden index, performed well, even better than the combinations of several screening tests. The Mini-Cog with excellent screening characteristics, spending less time, could be considered to be used as a screening test to help to screen patients with cognitive impairment or dementia early. And Bayesian method was shown to be a suitable tool for evaluating dementia screening tests. The Mini-Cog with excellent screening characteristics, spending less time, could be considered to be used as a screening test to help to screen patients with cognitive impairment or dementia early. And Bayesian method was shown to be a suitable tool for evaluating dementia screening tests.

  5. The Utility of the Mini-Addenbrooke's Cognitive Examination as a Screen for Cognitive Impairment in Elderly Patients with Chronic Kidney Disease and Diabetes.

    Science.gov (United States)

    Hobson, Peter; Rohoma, Kamel H; Wong, Stephen P; Kumwenda, Mick J

    2016-01-01

    We tested the utility of the Mini-Addenbrooke's Cognitive Examination (M-ACE) in a cohort of older adults with chronic kidney disease (CKD) and diabetes. The M-ACE was administered to 112 CKD and diabetes patients attending a nephrology clinic. Cognitive impairment was based upon patient, informant, and case review, neuropsychological assessment, and application of criteria for mild cognitive impairment (MCI) and the Diagnostic and Statistical Manual of Mental Disorders, fifth edition for dementia. The M-ACE was also compared to the Mini-Mental State Examination (MMSE). Upon assessment, 52 patients had normal cognitive function, 33 had MCI, and 27 had dementia. The area under the receiver operating curve for the M-ACE was 0.96 (95% CI 0.95-1.00). The sensitivity and specificity for a dementia diagnosis were 0.96 and 0.84 at the cut point <25 and 0.70 and 1.00 at the cut point <21. Mean M-ACE scores differed significantly between normal, demented, and MCI groups ( p < 0.001), and compared to the MMSE, the M-ACE did not suffer from ceiling effects. The M-ACE is an easily administered test with good sensitivity and specificity to capture and assist in the diagnosis of MCI or dementia in patients with CKD and diabetes.

  6. Active Ester Containing Surfmer for One-Stage Polymer Nanoparticle Surface Functionalization in Mini-Emulsion Polymerization

    Directory of Open Access Journals (Sweden)

    Vanessa L. Albernaz

    2018-04-01

    Full Text Available Functional surface active monomers (surfmers are molecules that combine the functionalities of surface activity, polymerizability, and reactive groups. This study presents an improved pathway for the synthesis of the active ester containing surfmer p-(11-acrylamidoundecanoyloxyphenyl dimethylsulfonium methyl sulfate (AUPDS. Further, the preparation of poly(methyl methacrylate and polystyrene nanoparticles (NPs by mini-emulsion polymerization using AUPDS is investigated, leading to NPs with active ester groups on their surface. By systematically varying reaction parameters and reagent concentrations, it was found that AUPDS feed concentrations between 2–4 mol% yielded narrowly distributed and stable spherical particles with average sizes between 83 and 134 nm for non-cross-linked NPs, and up to 163 nm for cross-linked NPs. By basic hydrolysis of the active ester groups in aqueous dispersion, the positive ζ-potential (ZP was converted into a negative ZP and charge quantities determined by polyelectrolyte titrations before and after hydrolysis were in the same range, indicating that the active ester groups were indeed accessible in aqueous suspension. Increasing cross-linker amounts over 10 mol% also led to a decrease of ZP of NPs, probably due to internalization of the AUPDS during polymerization. In conclusion, by using optimized reaction conditions, it is possible to prepare active ester functionalized NPs in one stage using AUPDS as a surfmer in mini-emulsion polymerization.

  7. False positive diagnosis of malignancy in a case of cryptogenic organising pneumonia presenting as a pulmonary mass with mediastinal nodes detected on fluorodeoxyglucose-positron emission tomography: a case report

    Science.gov (United States)

    2009-01-01

    Introduction We report the case of a patient with positive findings on a lung emission tomography/computed tomography (PET/CT) scan, with possible contra lateral mediastinal involvement, which strongly suggested an inoperable lung carcinoma. The lung mass proved to be a cryptogenic organising pneumonia. While the latter has previously been shown to be PET/CT positive, mediastinal involvement simulating malignant spread has not been previously reported. Case presentation A 50-year-old Caucasian woman presented with a history of unproductive cough and was found to have a mass in the right upper lobe as shown on chest X-ray and a computed tomography scan. A subsequent PET/CT scan showed strong uptake in the right upper lobe (maximum standard uptake values (SUVmax) 9.6) with increased uptake in the adjacent mediastinum and contralateral mediastinal nodes. Surgical resection and mediastinoscopy revealed cryptogenic organising pneumonia, with enlarged reactive mediastinal lymph nodes. Conclusion The case illustrates the limits of PET/CT scanning as a diagnostic tool, and emphasizes the importance of obtaining histological confirmation of malignant diseases whenever possible. PMID:19946541

  8. Diagnosis and management of iatrogenic endoscopic perforations

    DEFF Research Database (Denmark)

    Paspatis, Gregorios A; Dumonceau, Jean-Marc; Barthet, Marc

    2014-01-01

    This Position Paper is an official statement of the European Society of Gastrointestinal Endoscopy (ESGE). It addresses the diagnosis and management of iatrogenic perforation occurring during diagnostic or therapeutic digestive endoscopic procedures. Main recommendations 1 ESGE recommends that ea...

  9. Molecular Diagnosis of Phytoplasmas

    Directory of Open Access Journals (Sweden)

    C. Marzachì

    2004-08-01

    Full Text Available Phytoplasmas are wall-less prokaryotes associated with diseases in numerous plant species worldwide. In nature they are transmitted by phloem-sucking insects. Yellowing, decline, witches’ broom, leaf curl, floral virescence and phyllody are the most conspicuous symptoms associated with phytoplasmas, although infections are sometimes asymptomatic. Since phytoplasmas cannot be cultured in vitro, molecular techniques are needed for their diagnosis and characterization. The titer of phytoplasma cells in the phloem of infected plants may vary according to the season and the plant species, and it is often very low in woody hosts. Different DNA extraction procedures have therefore been tried out to obtain phytoplasma DNA at a concentration and purity high enough for effective diagnosis. DNA/DNA hybridization methods were reported in the nineties to be appropriate for the detection of phytoplasmas, but at present PCR is considered the most suitable. Universal and group-specific primers have been designed on the rRNA operon of the phytoplasma genome and on plasmid sequences. RFLP analysis of the obtained amplicons has classified these pathogens into major 16Sr RNA groups. Group-specific primers have also been designed on other genomic sequences. PCR is a very sensitive technique, but due to the low titre of phytoplasmas a further increase in sensitivity may be required for accurate diagnosis. This is routinely obtained with a second round of PCR (nested PCR. The drawback of nested PCR is that there is a greater chance of obtaining false positives due to contamination. Many authors have therefore developed protocols based on hybridization (PCR/dot blot or serological approaches (PCR/ELISA to increase the sensitivity and specificity of the direct PCR, reducing the risks due to nested PCR. Real time PCR protocols may also improve the sensitivity and specificity of the direct PCR assay.

  10. Targeting MicroRNA Function in Respiratory Diseases: Mini-review

    Directory of Open Access Journals (Sweden)

    Steven eMaltby

    2016-02-01

    Full Text Available MicroRNAs (miRNAs are small non-coding RNA molecules that modulate expression of the majority of genes by inhibiting protein translation. Growing literature has identified functional roles for miRNAs across a broad range of biological processes. As such, miRNAs are recognised as potential disease biomarkers and novel targets for therapies. While several miRNA-targeted therapies are currently in clinical trials (e.g. for the treatment of hepatitis C virus infection and cancer, no therapies have targeted miRNAs in respiratory diseases in the clinic. In this mini-review, we review the current knowledge on miRNA expression and function in respiratory diseases, intervention strategies to target miRNA function and considerations specific to respiratory diseases. Altered miRNA expression profiles have been reported in a number of respiratory diseases, including asthma, chronic obstructive pulmonary disease, cystic fibrosis and idiopathic pulmonary fibrosis. These include alterations in isolated lung tissue, as well as sputum, bronchoalveolar lavage fluids and peripheral blood or serum. The observed alterations in easily accessible body fluids (e.g. serum have been proposed as new biomarkers that may inform disease diagnosis and patient management. In a subset of studies, miRNA-targeted interventions also improved disease outcomes, indicating functional roles for altered miRNA expression in disease pathogenesis. In fact, direct administration of miRNA-targeting molecules to the lung has yielded promising results in a number of animal models. The ability to directly administer compounds to the lung holds considerable promise and may limit potential off-target effects and side effects caused by the systemic administration required to treat other diseases.

  11. [Effectiveness of the Mini-Mental State for detection of cognitive impairment in primary care].

    Science.gov (United States)

    Carnero Pardo, Cristóbal; Cruz Orduña, Isabel; Espejo Martínez, Beatriz; Cárdenas Viedma, Salvador; Torrero García, Pedro; Olazarán Rodríguez, Javier

    2013-10-01

    To evaluate the diagnostic accuracy (DA) of the Mini-Mental State (MMS) for the detection of cognitive impairment (CI) in Primary Care (PC) and to determine the best conditions of use for that purpose. Pooled analysis of two prospective, double blind, studies on the evaluation of diagnostic tools with complete verification that were conducted in Madrid and Granada (Spain). The MMS was administered in PC and the final cognitive diagnosis (gold standard) was made in Specialized Care. Subjects with cognitive complaints or suspected of having CI were consecutively recruited in the PC clinic. The DA of the MMS was evaluated using the area under the receiver operating characteristic (ROC) curve (AUC). The best cut-off point was selected according to the ratio of cases correctly classified (RCC) and to the kappa index. Direct (MMSd) and age- and education-adjusted (MMSa) total scores were analyzed separately. In the total sample of 360 subjects (214 CI), the DA of the MMSd was significantly superior to that of the MMSa (0.84±0.02 vs 0.82±0.02, p≤.001). The yield obtained by the best cut-off point of the MMSd (22/23) was modest (RCC 0.77, kappa 0.52±0.05) and was not improved by any MMSa cut-off point. The DA of the MMS for detection of CI in PC was modest and did not improve with adjustment of the score by age and education. The best cut-off point was 22/23, inferior to the usually recommended cut-off. Copyright © 2013 Elsevier España, S.L. All rights reserved.

  12. Montreal Cognitive Assessment and Mini-Mental State Examination are both valid cognitive tools in stroke.

    Science.gov (United States)

    Cumming, T B; Churilov, L; Linden, T; Bernhardt, J

    2013-08-01

    To determine the validity of the Montreal Cognitive Assessment (MoCA) and the Mini-Mental State Examination (MMSE) as screening tools for cognitive impairment after stroke. Cognitive assessments were administered over 2 sessions (1 week apart) at 3 months post-stroke. Scores on the MoCA and MMSE were evaluated against a diagnosis of cognitive impairment derived from a comprehensive neuropsychological battery (the criterion standard). Sixty patients participated in the study [mean age 72.1 years (SD = 13.9), mean education 10.5 years (SD = 3.9), median acute NIHSS score 5 (IQR 3-7)]. The MoCA yielded lower scores (median = 21, IQR = 17-24; mean = 20.0, SD = 5.4) than the MMSE (median = 26, IQR = 22-27; mean = 24.2, SD = 4.5). MMSE data were more skewed towards ceiling than MoCA data (skewness = -1.09 vs -0.73). Area under the receiver operator curve was higher for MoCA than for MMSE (0.87 vs 0.84), although this difference was not significant (χ(2) = 0.48, P = 0.49). At their optimal cut-offs, the MoCA had better sensitivity than the MMSE (0.92 vs 0.82) but poorer specificity (0.67 vs 0.76). The MoCA is a valid screening tool for post-stroke cognitive impairment; it is more sensitive but less specific than the MMSE. Contrary to the prevailing view, the MMSE also exhibited acceptable validity in this setting. © 2013 John Wiley & Sons A/S.

  13. Mini Nutritional Assessment for Hospitalized Patients in King Khalid Hospital at Hail city in Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Rafia Bano

    2016-12-01

    Full Text Available Introduction: The Mini Nutritional Assessment (MNA has been developed to assess malnutrition in elderly  and to filter those who might get benefited from early diagnosis and treatment. The objective of the present study was to examine the nutritional profile of old age hospitalized individuals through the use of the MNA in King Khalid Hospital at Hail city of Saudi Arabia. Methods: Demographic data was gathered through a questionnaire and a modified version of MNA, which was translated into Arabic and applied to 100 elderly females aged ≥ 45 years to assess their nutritional status . The MNA version modified by  Nestle and translated into Arabic was used to evaluate the patients for this study. The descriptive analysis of variables is shown as the average ± one standard deviation. Results: Mean age of the participants was 61.12±12.4 years ranging from 45 to 92 years. The mean body mass index of total population was found to be 26.9±5.2 ranging from 18.3 to 46.5 kg/m2. The assessment scores and total malnutrition score was found to be decreasing with increasing age, showing a significant inverse correlation (P<0.01. Furthermore, the difference in the screening scores according to the age was found to be statistically insignificant. Conclusion: Because of the high prevalence of elderly patients that were malnourished or at risk of malnutrition, a more detailed evaluation of nutritional status, along with a regular follow up and dietary intervention to reverse the situation, of these patients is recommended.

  14. Positional games

    CERN Document Server

    Hefetz, Dan; Stojaković, Miloš; Szabó, Tibor

    2014-01-01

    This text serves as a thorough introduction to the rapidly developing field of positional games. This area constitutes an important branch of combinatorics, whose aim it is to systematically develop an extensive mathematical basis for a variety of two-player perfect information games. These range from such popular games as Tic-Tac-Toe and Hex to purely abstract games played on graphs and hypergraphs. The subject of positional games is strongly related to several other branches of combinatorics such as Ramsey theory, extremal graph and set theory, and the probabilistic method. These notes cover a variety of topics in positional games, including both classical results and recent important developments. They are presented in an accessible way and are accompanied by exercises of varying difficulty, helping the reader to better understand the theory. The text will benefit both researchers and graduate students in combinatorics and adjacent fields.

  15. Diagnosis of Clostridium difficile

    DEFF Research Database (Denmark)

    Jensen, M B F; Olsen, K E P; Nielsen, X C

    2015-01-01

    The diagnosis of Clostridium difficile infection (CDI) requires the detection of toxigenic C. difficile or its toxins and a clinical assessment. We evaluated the performance of four nucleic acid amplification tests (NAATs) detecting toxigenic C. difficile directly from faeces compared to routine...... ribotyping and toxinotyping (TT) were performed on culture-positive samples. In parallel, the samples were analysed by four NAATs; two targeting tcdA or tcdB (illumigene® C. difficile and PCRFast® C. difficile A/B) and two multi-target real-time (RT) PCR assays also targeting cdt and tcdC alleles...... characteristic of epidemic and potentially more virulent PCR ribotypes 027, 066 and 078 (GeneXpert® C. difficile/Epi and an 'in-house RT PCR' two-step algorithm). The multi-target assays were significantly more sensitive compared to routine toxigenic culture (p 

  16. A new mini-extrapolation chamber for beta source uniformity measurements

    International Nuclear Information System (INIS)

    Oliveira, M.L.; Caldas, L.V.E.

    2006-01-01

    According to recent international recommendations, beta particle sources should be specified in terms of absorbed dose rates to water at the reference point. However, because of the clinical use of these sources, additional information should be supplied in the calibration reports. This additional information include the source uniformity. A new small volume extrapolation chamber was designed and constructed at the Calibration Laboratory at Instituto de Pesquisas Energeticas e Nucleares, IPEN, Brazil, for the calibration of 90 Sr+ 90 Y ophthalmic plaques. This chamber can be used as a primary standard for the calibration of this type of source. Recent additional studies showed the feasibility of the utilization of this chamber to perform source uniformity measurements. Because of the small effective electrode area, it is possible to perform independent measurements by varying the chamber position by small steps. The aim of the present work was to study the uniformity of a 90 Sr+ 90 Y plane ophthalmic plaque utilizing the mini extrapolation chamber developed at IPEN. The uniformity measurements were performed by varying the chamber position by steps of 2 mm in the source central axis (x-and y-directions) and by varying the chamber position off-axis by 3 mm steps. The results obtained showed that this small volume chamber can be used for this purpose with a great advantage: it is a direct method, being unnecessary a previously calibration of the measurement device in relation to a reference instrument, and it provides real -time results, reducing the time necessary for the study and the determination of the uncertainties related to the measurements. (authors)

  17. Early hemi-diaphragmatic plication through a video assisted mini-thoracotomy in postcardiotomy phrenic nerve paresis

    Science.gov (United States)

    Tsakiridis, Kosmas; Visouli, Aikaterini N.; Machairiotis, Nikolaos; Christofis, Christos; Stylianaki, Aikaterini; Katsikogiannis, Nikolaos; Mpakas, Andreas; Courcoutsakis, Nicolaos; Zarogoulidis, Konstantinos

    2012-01-01

    New symptom onset of respiratory distress without other cause, and new hemi-diaphragmatic elevation on chest radiography postcardiotomy, are usually adequate for the diagnosis of phrenic nerve paresis. The symptom severity varies (asymptomatic state to severe respiratory failure) depending on the degree of the lesion (paresis vs. paralysis), the laterality (unilateral or bilateral), the age, and the co-morbidity (respiratory, cardiac disease, morbid obesity, etc). Surgical treatment (hemi-diaphragmatic plication) is indicated only in the presence of symptoms. The established surgical treatment is plication of the affected hemidiaphragm which is generally considered safe and effective. Several techniques and approaches are employed for diaphragmatic plication (thoracotomy, video-assisted thoracoscopic surgery, video-assisted mini-thoracotomy, laparoscopic surgery). The timing of surgery depends on the severity and the progression of symptoms. In infants and young children with postcardiotomy phrenic nerve paresis the clinical status is usually severe (failure to wean from mechanical ventilation), and early plication is indicated. Adults with postcardiotomy phrenic nerve paresis usually suffer from chronic dyspnoea, and, in the absence of respiratory distress, conservative treatment is recommended for 6 months -2 years, since improvement is often observed. Nevertheless, earlier surgical treatment may be indicated in non-resolving respiratory failure. We present early (25th day postcardiotomy) right hemi-diaphragm plication, through a video assisted mini-thoracotomy in a high risk patient with postcardiotomy phrenic nerve paresis and respiratory distress. Early surgery with minimal surgical trauma, short operative time, minimal blood loss and postoperative pain, led to fast rehabilitation and avoidance of prolonged hospitalization complications. The relevant literature is discussed. PMID:23304442

  18. Modeling Image Patches with a Generic Dictionary of Mini-Epitomes

    Science.gov (United States)

    Papandreou, George; Chen, Liang-Chieh; Yuille, Alan L.

    2015-01-01

    The goal of this paper is to question the necessity of features like SIFT in categorical visual recognition tasks. As an alternative, we develop a generative model for the raw intensity of image patches and show that it can support image classification performance on par with optimized SIFT-based techniques in a bag-of-visual-words setting. Key ingredient of the proposed model is a compact dictionary of mini-epitomes, learned in an unsupervised fashion on a large collection of images. The use of epitomes allows us to explicitly account for photometric and position variability in image appearance. We show that this flexibility considerably increases the capacity of the dictionary to accurately approximate the appearance of image patches and support recognition tasks. For image classification, we develop histogram-based image encoding methods tailored to the epitomic representation, as well as an “epitomic footprint” encoding which is easy to visualize and highlights the generative nature of our model. We discuss in detail computational aspects and develop efficient algorithms to make the model scalable to large tasks. The proposed techniques are evaluated with experiments on the challenging PASCAL VOC 2007 image classification benchmark. PMID:26321859

  19. Why is Mini-Mental state examination performance correlated with estimated premorbid cognitive ability?

    Science.gov (United States)

    Dykiert, D; Der, G; Starr, J M; Deary, I J

    2016-09-01

    Tests requiring the pronunciation of irregular words are used to estimate premorbid cognitive ability in patients with clinical diagnoses, and prior cognitive ability in normal ageing. However, scores on these word-reading tests correlate with scores on the Mini-Mental State Examination (MMSE), a widely used screening test for possible cognitive pathology. This study aimed to test whether the word-reading tests' correlations with MMSE scores in healthy older people are explained by childhood IQ or education. Wechsler Test of Adult Reading (WTAR), National Adult Reading Test (NART), MMSE scores and information about education were obtained from 1024 70-year-olds, for whom childhood intelligence test scores were available. WTAR and NART were positively correlated with the MMSE (r ≈ 0.40, p < 0.001). The shared variance of WTAR and NART with MMSE was significantly attenuated by ~70% after controlling for childhood intelligence test scores. Education explained little additional variance in the association between the reading tests and the MMSE. MMSE, which is often used to index cognitive impairment, is associated with prior cognitive ability. MMSE score is related to scores on WTAR and NART largely due to their shared association with prior ability. Obtained MMSE scores should be interpreted in the context of prior ability (or WTAR/NART score as its proxy).

  20. Minimally invasive mini open split-muscular percutaneous pedicle screw fixation of the thoracolumbar spine

    Directory of Open Access Journals (Sweden)

    Murat Ulutaş

    2015-03-01

    Full Text Available We prospectively assessed the feasibility and safety of a new percutaneous pedicle screw (PPS fixation technique for instrumentation of the thoracic and lumbar spine in this study. All patients were operated in the prone position under general anesthesia. A 6 to 8 cm midline skin incision was made and wide sub-cutaneous dissection was performed. The paravertebral muscles were first dissected subperiosteally into the midline incision of the fascia for lumbar microdiscectomy with transforaminal lumbar interbody fusion cage implantation. After the secondary paramedian incisions on the fascia, the PPSs were inserted via cleavage of the multifidus muscles directly into the pedicles under fluoroscopy visualization. A total of 35 patients underwent surgery with this new surgical technique. The control group for operative time, blood loss and analgesic usage consisted of 35 randomly selected cases from our department. The control group underwent surgery via conventional pedicle screw instrumentation with paramedian fusion. All patients in the minimal invasive surgery series were ambulatory with minimal pain on the first postoperative day. The operation time and blood loss and the postoperative analgesic consumption were significantly less with this new technique. In conclusion, the minimal invasive mini open split-muscular percutaneous pedicle screw fixation technique is safe and feasible. It can be performed via a short midline skin incision and can also be combined with interbody fusion, causing minimal pain without severe muscle damage.